DC74_RS31730 88c6dac75347aeca079efb65d8bb209a 271 Pfam PF01909 Nucleotidyltransferase domain 12 45 4.3E-6 T 23-04-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DC74_RS31730 88c6dac75347aeca079efb65d8bb209a 271 SUPERFAMILY SSF81301 2 72 3.6E-11 T 23-04-2016 DC74_RS31730 88c6dac75347aeca079efb65d8bb209a 271 Gene3D G3DSA:3.30.460.10 3 65 1.0E-11 T 23-04-2016 DC74_RS31570 537de4b5b95199966cc9fda525fd4a6b 344 PANTHER PTHR32419 21 334 8.6E-145 T 23-04-2016 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 DC74_RS31570 537de4b5b95199966cc9fda525fd4a6b 344 Pfam PF13409 Glutathione S-transferase, N-terminal domain 54 147 7.6E-9 T 23-04-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 DC74_RS31570 537de4b5b95199966cc9fda525fd4a6b 344 Gene3D G3DSA:3.40.30.10 29 168 7.6E-12 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS31570 537de4b5b95199966cc9fda525fd4a6b 344 SUPERFAMILY SSF47616 163 332 1.67E-33 T 23-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like DC74_RS31570 537de4b5b95199966cc9fda525fd4a6b 344 SUPERFAMILY SSF52833 30 142 2.46E-5 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS31570 537de4b5b95199966cc9fda525fd4a6b 344 Gene3D G3DSA:1.20.1050.10 169 279 3.4E-23 T 23-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like DC74_RS31570 537de4b5b95199966cc9fda525fd4a6b 344 PIRSF PIRSF015753 13 316 8.4E-104 T 23-04-2016 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 DC74_RS31570 537de4b5b95199966cc9fda525fd4a6b 344 Pfam PF13410 Glutathione S-transferase, C-terminal domain 196 265 1.6E-11 T 23-04-2016 DC74_RS31570 537de4b5b95199966cc9fda525fd4a6b 344 PANTHER PTHR32419:SF6 21 334 8.6E-145 T 23-04-2016 DC74_RS34195 ac175d1d98deebb41c4d5b4f4e13c837 1093 SUPERFAMILY SSF48452 392 516 2.85E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS34195 ac175d1d98deebb41c4d5b4f4e13c837 1093 SUPERFAMILY SSF48452 549 600 2.85E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS34195 ac175d1d98deebb41c4d5b4f4e13c837 1093 Gene3D G3DSA:1.25.40.10 391 534 4.4E-11 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS34195 ac175d1d98deebb41c4d5b4f4e13c837 1093 Gene3D G3DSA:1.25.40.10 569 599 4.4E-11 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS34195 ac175d1d98deebb41c4d5b4f4e13c837 1093 Pfam PF12770 CHAT domain 804 1092 1.1E-39 T 23-04-2016 IPR024983 CHAT domain DC74_RS22720 20f8af9e11e211e7a7f3b78ebc6ff383 310 PANTHER PTHR30005 1 305 9.3E-89 T 23-04-2016 DC74_RS22720 20f8af9e11e211e7a7f3b78ebc6ff383 310 Gene3D G3DSA:3.30.420.150 124 305 3.3E-48 T 23-04-2016 DC74_RS22720 20f8af9e11e211e7a7f3b78ebc6ff383 310 Gene3D G3DSA:3.30.420.40 1 123 2.0E-34 T 23-04-2016 DC74_RS22720 20f8af9e11e211e7a7f3b78ebc6ff383 310 Pfam PF02541 Ppx/GppA phosphatase family 30 305 1.8E-74 T 23-04-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40|UniPathway: UPA00908 DC74_RS22720 20f8af9e11e211e7a7f3b78ebc6ff383 310 SUPERFAMILY SSF53067 129 306 1.9E-36 T 23-04-2016 DC74_RS22720 20f8af9e11e211e7a7f3b78ebc6ff383 310 SUPERFAMILY SSF53067 2 125 2.33E-31 T 23-04-2016 DC74_RS12255 9286bf628b27c03974aa53ee895f9bb7 263 Pfam PF12840 Helix-turn-helix domain 19 78 2.2E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS12255 9286bf628b27c03974aa53ee895f9bb7 263 SMART SM00418 19 98 1.0E-14 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS12255 9286bf628b27c03974aa53ee895f9bb7 263 PANTHER PTHR39168:SF1 1 240 3.1E-50 T 23-04-2016 DC74_RS12255 9286bf628b27c03974aa53ee895f9bb7 263 Gene3D G3DSA:1.10.10.10 9 98 1.2E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS12255 9286bf628b27c03974aa53ee895f9bb7 263 SUPERFAMILY SSF46785 10 98 6.06E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS12255 9286bf628b27c03974aa53ee895f9bb7 263 PANTHER PTHR39168 1 240 3.1E-50 T 23-04-2016 DC74_RS04110 f94db53376c7cb85c86771534b76bfde 189 Gene3D G3DSA:1.20.120.450 21 188 9.0E-36 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS04110 f94db53376c7cb85c86771534b76bfde 189 Pfam PF04978 Protein of unknown function (DUF664) 42 185 1.3E-35 T 23-04-2016 IPR007061 Protein of unknown function DUF664 DC74_RS04110 f94db53376c7cb85c86771534b76bfde 189 SUPERFAMILY SSF109854 14 184 1.68E-35 T 23-04-2016 DC74_RS12160 a047730110606949a4ce83497f83120a 291 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 220 262 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS12160 a047730110606949a4ce83497f83120a 291 Gene3D G3DSA:1.10.10.60 173 220 3.9E-4 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS12160 a047730110606949a4ce83497f83120a 291 SUPERFAMILY SSF51215 6 160 3.01E-22 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS12160 a047730110606949a4ce83497f83120a 291 PANTHER PTHR11019 38 274 1.1E-26 T 23-04-2016 DC74_RS12160 a047730110606949a4ce83497f83120a 291 Gene3D G3DSA:2.60.120.280 35 161 8.6E-20 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS12160 a047730110606949a4ce83497f83120a 291 SMART SM00342 183 266 7.3E-24 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS12160 a047730110606949a4ce83497f83120a 291 PANTHER PTHR11019:SF45 38 274 1.1E-26 T 23-04-2016 DC74_RS12160 a047730110606949a4ce83497f83120a 291 Pfam PF02311 AraC-like ligand binding domain 35 146 7.4E-11 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS12160 a047730110606949a4ce83497f83120a 291 SUPERFAMILY SSF46689 219 270 1.34E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS12160 a047730110606949a4ce83497f83120a 291 Gene3D G3DSA:1.10.10.60 221 269 9.6E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS12160 a047730110606949a4ce83497f83120a 291 Pfam PF12833 Helix-turn-helix domain 190 268 3.6E-19 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS12160 a047730110606949a4ce83497f83120a 291 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 250 266 1.4E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS12160 a047730110606949a4ce83497f83120a 291 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 235 250 1.4E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Gene3D G3DSA:3.40.47.10 355 518 8.2E-58 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 103 341 1.6E-83 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SMART SM00823 Phosphopantetheine attachment site 14 85 0.012 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SMART SM00823 Phosphopantetheine attachment site 1420 1491 1.3E-10 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SUPERFAMILY SSF55048 1154 1217 2.22E-8 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 PANTHER PTHR11712 1 527 0.0 T 23-04-2016 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 PANTHER PTHR11712 938 1413 0.0 T 23-04-2016 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 PANTHER PTHR11712 2007 2015 0.0 T 23-04-2016 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Gene3D G3DSA:3.40.366.10 1217 1330 3.9E-67 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Gene3D G3DSA:3.40.366.10 1023 1149 3.9E-67 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Pfam PF00668 Condensation domain 1581 1870 6.4E-54 T 23-04-2016 IPR001242 Condensation domain DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 350 465 2.9E-41 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Gene3D G3DSA:1.10.1200.10 13 108 4.2E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SMART SM00825 Beta-ketoacyl synthase 105 518 4.4E-184 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SUPERFAMILY SSF47336 1414 1511 3.53E-17 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 603 891 2.6E-84 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1030 1326 5.5E-86 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 ProSitePatterns PS00012 Phosphopantetheine attachment site. 40 55 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1446 1461 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Gene3D G3DSA:3.40.366.10 787 904 7.1E-66 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Gene3D G3DSA:3.40.366.10 592 721 7.1E-66 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Pfam PF13745 HxxPF-repeated domain 1892 1994 1.6E-11 T 23-04-2016 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SUPERFAMILY SSF47336 10 117 1.96E-16 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SUPERFAMILY SSF52777 1760 2012 1.45E-40 T 23-04-2016 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Pfam PF00550 Phosphopantetheine attachment site 1422 1487 1.2E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Pfam PF00550 Phosphopantetheine attachment site 16 81 2.1E-8 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SUPERFAMILY SSF52151 1026 1155 2.88E-60 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SUPERFAMILY SSF52151 1219 1317 2.88E-60 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SUPERFAMILY SSF52777 1584 1752 4.67E-41 T 23-04-2016 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Gene3D G3DSA:1.10.1200.10 1421 1489 2.7E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 468 522 5.3E-9 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Pfam PF00698 Acyl transferase domain 1030 1340 5.4E-66 T 23-04-2016 IPR014043 Acyl transferase DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Pfam PF00698 Acyl transferase domain 602 899 4.1E-68 T 23-04-2016 IPR014043 Acyl transferase DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SUPERFAMILY SSF52151 788 884 1.02E-59 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SUPERFAMILY SSF52151 599 726 1.02E-59 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 Gene3D G3DSA:3.40.47.10 109 354 3.3E-94 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SUPERFAMILY SSF53901 493 514 8.87E-95 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SUPERFAMILY SSF53901 238 461 8.87E-95 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS05985 7cc14ceae29a6e825dde98283436677a 2028 SUPERFAMILY SSF53901 101 211 8.87E-95 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS34855 8441ef0e998c248a3274ac47eeb20cae 501 SMART SM00345 40 99 5.9E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS34855 8441ef0e998c248a3274ac47eeb20cae 501 PANTHER PTHR11751 106 480 1.4E-81 T 23-04-2016 DC74_RS34855 8441ef0e998c248a3274ac47eeb20cae 501 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 73 89 4.3E-9 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS34855 8441ef0e998c248a3274ac47eeb20cae 501 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 73 4.3E-9 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS34855 8441ef0e998c248a3274ac47eeb20cae 501 PANTHER PTHR11751:SF294 106 480 1.4E-81 T 23-04-2016 DC74_RS34855 8441ef0e998c248a3274ac47eeb20cae 501 Gene3D G3DSA:3.90.1150.10 351 482 2.5E-20 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS34855 8441ef0e998c248a3274ac47eeb20cae 501 SUPERFAMILY SSF53383 118 482 7.79E-76 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS34855 8441ef0e998c248a3274ac47eeb20cae 501 Gene3D G3DSA:1.10.10.10 33 98 8.3E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34855 8441ef0e998c248a3274ac47eeb20cae 501 SUPERFAMILY SSF46785 33 103 4.38E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34855 8441ef0e998c248a3274ac47eeb20cae 501 Gene3D G3DSA:3.40.640.10 136 350 2.6E-43 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS34855 8441ef0e998c248a3274ac47eeb20cae 501 Pfam PF00392 Bacterial regulatory proteins, gntR family 37 96 9.4E-15 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS34855 8441ef0e998c248a3274ac47eeb20cae 501 Pfam PF00155 Aminotransferase class I and II 161 478 1.2E-30 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SMART SM00826 908 1072 6.8E-61 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Pfam PF00698 Acyl transferase domain 552 860 2.6E-57 T 23-04-2016 IPR014043 Acyl transferase DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 1.6E-46 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 5.3E-85 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Gene3D G3DSA:3.40.366.10 735 855 4.8E-80 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Gene3D G3DSA:3.40.366.10 541 669 4.8E-80 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1663 1678 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SUPERFAMILY SSF53901 32 409 1.74E-103 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Gene3D G3DSA:3.40.47.10 37 297 6.0E-91 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 PANTHER PTHR11712 31 1704 0.0 T 23-04-2016 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 PANTHER PTHR11712:SF242 31 1704 0.0 T 23-04-2016 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SUPERFAMILY SSF55048 673 734 5.89E-11 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Pfam PF08659 KR domain 1354 1530 9.2E-57 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SUPERFAMILY SSF51735 1350 1587 5.67E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Pfam PF14765 Polyketide synthase dehydratase 908 1169 5.5E-41 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Gene3D G3DSA:3.40.50.720 1354 1550 3.8E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 509 6.8E-12 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SUPERFAMILY SSF47336 1630 1718 1.57E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SMART SM00823 Phosphopantetheine attachment site 1636 1708 1.1E-31 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SMART SM00825 Beta-ketoacyl synthase 37 463 8.7E-215 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Gene3D G3DSA:3.40.47.10 298 463 2.7E-65 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SUPERFAMILY SSF51735 1185 1340 3.66E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SMART SM01294 1637 1704 2.4E-5 T 23-04-2016 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Pfam PF00550 Phosphopantetheine attachment site 1638 1704 2.2E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Gene3D G3DSA:1.10.1200.10 1635 1708 2.6E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SUPERFAMILY SSF52151 549 674 1.62E-73 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SUPERFAMILY SSF52151 735 831 1.62E-73 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1354 1532 3.8E-57 T 23-04-2016 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 Gene3D G3DSA:3.30.70.250 673 734 2.0E-7 T 23-04-2016 DC74_RS06830 f7729f89284d72fed7406b17d5e3d1b9 1793 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 552 841 8.3E-126 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.1E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.1E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.1E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.1E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.1E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 PANTHER PTHR24322 148 179 2.6E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 PANTHER PTHR24322 2 132 2.6E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 SUPERFAMILY SSF51735 2 244 7.84E-75 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 199 0.0097 T 23-04-2016 DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.4E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.4E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.4E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 Gene3D G3DSA:3.40.50.720 1 244 2.8E-77 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 4 243 1.1E-62 T 23-04-2016 DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 PANTHER PTHR24322:SF330 148 179 2.6E-48 T 23-04-2016 DC74_RS37240 bce6cf6d43acc781b0a5fe60eca5d4e6 245 PANTHER PTHR24322:SF330 2 132 2.6E-48 T 23-04-2016 DC74_RS19810 e2d22b06d75ed1cf4e633e2d4e2103cd 513 SMART SM00220 33 286 1.8E-48 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS19810 e2d22b06d75ed1cf4e633e2d4e2103cd 513 PANTHER PTHR24362:SF247 26 325 4.4E-99 T 23-04-2016 DC74_RS19810 e2d22b06d75ed1cf4e633e2d4e2103cd 513 Pfam PF00069 Protein kinase domain 33 283 2.4E-42 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS19810 e2d22b06d75ed1cf4e633e2d4e2103cd 513 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 39 61 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS19810 e2d22b06d75ed1cf4e633e2d4e2103cd 513 SUPERFAMILY SSF56112 29 294 2.53E-65 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS19810 e2d22b06d75ed1cf4e633e2d4e2103cd 513 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 151 163 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS19810 e2d22b06d75ed1cf4e633e2d4e2103cd 513 PANTHER PTHR24362 26 325 4.4E-99 T 23-04-2016 DC74_RS19810 e2d22b06d75ed1cf4e633e2d4e2103cd 513 Gene3D G3DSA:3.30.200.20 26 109 1.3E-14 T 23-04-2016 DC74_RS19810 e2d22b06d75ed1cf4e633e2d4e2103cd 513 Gene3D G3DSA:1.10.510.10 116 305 1.7E-44 T 23-04-2016 DC74_RS35290 3ef9d6ff22989bc04632be7293dd5fc4 182 Gene3D G3DSA:3.40.470.10 16 176 1.4E-54 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like DC74_RS35290 3ef9d6ff22989bc04632be7293dd5fc4 182 SMART SM00986 17 180 1.7E-8 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like DC74_RS35290 3ef9d6ff22989bc04632be7293dd5fc4 182 SUPERFAMILY SSF52141 16 175 6.21E-44 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like DC74_RS35290 3ef9d6ff22989bc04632be7293dd5fc4 182 SMART SM00987 17 180 1.7E-8 T 23-04-2016 DC74_RS35290 3ef9d6ff22989bc04632be7293dd5fc4 182 Pfam PF03167 Uracil DNA glycosylase superfamily 20 163 7.4E-27 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like DC74_RS35290 3ef9d6ff22989bc04632be7293dd5fc4 182 PANTHER PTHR12159 14 175 8.4E-63 T 23-04-2016 IPR015637 G/U mismatch-specific DNA glycosylase GO:0006281|GO:0019104 DC74_RS09415 5aa9a53856881f793100721c4f258954 206 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 19 195 9.2E-70 T 23-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 DC74_RS09415 5aa9a53856881f793100721c4f258954 206 ProSitePatterns PS00856 Guanylate kinase-like signature. 52 69 - T 23-04-2016 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 DC74_RS09415 5aa9a53856881f793100721c4f258954 206 PANTHER PTHR23117 9 197 1.5E-86 T 23-04-2016 DC74_RS09415 5aa9a53856881f793100721c4f258954 206 SMART SM00072 17 199 1.6E-61 T 23-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit DC74_RS09415 5aa9a53856881f793100721c4f258954 206 Pfam PF00625 Guanylate kinase 18 194 7.1E-44 T 23-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit DC74_RS09415 5aa9a53856881f793100721c4f258954 206 Gene3D G3DSA:3.30.63.10 48 99 4.2E-27 T 23-04-2016 DC74_RS09415 5aa9a53856881f793100721c4f258954 206 Gene3D G3DSA:3.40.50.300 16 40 2.4E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09415 5aa9a53856881f793100721c4f258954 206 Gene3D G3DSA:3.40.50.300 100 197 2.4E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09415 5aa9a53856881f793100721c4f258954 206 SUPERFAMILY SSF52540 16 196 6.32E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09415 5aa9a53856881f793100721c4f258954 206 Hamap MF_00328 Guanylate kinase [gmk]. 16 199 35.735 T 23-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 DC74_RS21985 72b6611196bfc9f3b0eb282769dd6547 675 Gene3D G3DSA:1.20.1050.40 11 138 3.2E-15 T 23-04-2016 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal DC74_RS21985 72b6611196bfc9f3b0eb282769dd6547 675 SUPERFAMILY SSF55486 11 669 3.4E-146 T 23-04-2016 DC74_RS21985 72b6611196bfc9f3b0eb282769dd6547 675 PANTHER PTHR11804:SF47 2 670 1.2E-290 T 23-04-2016 DC74_RS21985 72b6611196bfc9f3b0eb282769dd6547 675 Gene3D G3DSA:1.10.1370.10 495 672 9.5E-93 T 23-04-2016 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 DC74_RS21985 72b6611196bfc9f3b0eb282769dd6547 675 Gene3D G3DSA:1.10.1370.10 144 342 9.5E-93 T 23-04-2016 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 DC74_RS21985 72b6611196bfc9f3b0eb282769dd6547 675 Gene3D G3DSA:3.40.390.10 352 494 1.7E-47 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 DC74_RS21985 72b6611196bfc9f3b0eb282769dd6547 675 Pfam PF01432 Peptidase family M3 230 667 2.1E-98 T 23-04-2016 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 DC74_RS21985 72b6611196bfc9f3b0eb282769dd6547 675 PANTHER PTHR11804 2 670 1.2E-290 T 23-04-2016 DC74_RS05115 d1ff47d9f6627eab4e48b88850032898 118 PANTHER PTHR35174:SF3 3 113 1.0E-13 T 23-04-2016 DC74_RS05115 d1ff47d9f6627eab4e48b88850032898 118 Pfam PF03795 YCII-related domain 49 113 1.7E-8 T 23-04-2016 IPR005545 YCII-related DC74_RS05115 d1ff47d9f6627eab4e48b88850032898 118 SUPERFAMILY SSF54909 25 113 1.1E-14 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS05115 d1ff47d9f6627eab4e48b88850032898 118 Gene3D G3DSA:3.30.70.1060 1 115 1.5E-20 T 23-04-2016 DC74_RS05115 d1ff47d9f6627eab4e48b88850032898 118 PANTHER PTHR35174 3 113 1.0E-13 T 23-04-2016 DC74_RS01215 b8b6cd753c01214edfb227c6355e2a6d 227 Pfam PF00571 CBS domain 8 59 4.3E-8 T 23-04-2016 IPR000644 CBS domain DC74_RS01215 b8b6cd753c01214edfb227c6355e2a6d 227 Pfam PF00571 CBS domain 89 143 2.3E-15 T 23-04-2016 IPR000644 CBS domain DC74_RS01215 b8b6cd753c01214edfb227c6355e2a6d 227 PANTHER PTHR11911 7 149 2.1E-28 T 23-04-2016 DC74_RS01215 b8b6cd753c01214edfb227c6355e2a6d 227 PIRSF PIRSF036990 6 223 1.5E-60 T 23-04-2016 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON DC74_RS01215 b8b6cd753c01214edfb227c6355e2a6d 227 Gene3D G3DSA:3.20.20.70 4 219 8.0E-30 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS01215 b8b6cd753c01214edfb227c6355e2a6d 227 Pfam PF04972 BON domain 146 211 1.9E-12 T 23-04-2016 IPR007055 BON domain DC74_RS01215 b8b6cd753c01214edfb227c6355e2a6d 227 SUPERFAMILY SSF54631 6 148 3.77E-32 T 23-04-2016 DC74_RS01215 b8b6cd753c01214edfb227c6355e2a6d 227 SMART SM00116 96 144 4.5E-11 T 23-04-2016 IPR000644 CBS domain DC74_RS01215 b8b6cd753c01214edfb227c6355e2a6d 227 SMART SM00116 15 63 0.071 T 23-04-2016 IPR000644 CBS domain DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 Pfam PF00571 CBS domain 199 256 5.3E-8 T 23-04-2016 IPR000644 CBS domain DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 Pfam PF00571 CBS domain 272 321 3.7E-7 T 23-04-2016 IPR000644 CBS domain DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 SUPERFAMILY SSF56176 335 397 1.42E-10 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 PANTHER PTHR22777 4 435 1.1E-203 T 23-04-2016 DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 Gene3D G3DSA:3.30.465.10 329 424 1.8E-18 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 SUPERFAMILY SSF54631 194 337 1.12E-34 T 23-04-2016 DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 Pfam PF03471 Transporter associated domain 338 422 1.9E-12 T 23-04-2016 IPR005170 Transporter-associated domain DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 SMART SM00116 273 321 1.4 T 23-04-2016 IPR000644 CBS domain DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 SMART SM00116 208 257 0.0022 T 23-04-2016 IPR000644 CBS domain DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 SMART SM01091 336 428 5.8E-13 T 23-04-2016 IPR005170 Transporter-associated domain DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 Gene3D G3DSA:3.10.580.10 185 328 9.8E-24 T 23-04-2016 DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 PANTHER PTHR22777:SF17 4 435 1.1E-203 T 23-04-2016 DC74_RS14955 beb808746416e9a43d4dca2c2314de92 439 Pfam PF01595 Domain of unknown function DUF21 7 184 1.3E-30 T 23-04-2016 IPR002550 Domain of unknown function DUF21 DC74_RS06845 4c0cc17f78b545e8347c07d126e35cdc 902 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 853 869 1.1E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06845 4c0cc17f78b545e8347c07d126e35cdc 902 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 839 853 1.1E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06845 4c0cc17f78b545e8347c07d126e35cdc 902 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 869 881 1.1E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06845 4c0cc17f78b545e8347c07d126e35cdc 902 PANTHER PTHR16305 2 429 6.5E-18 T 23-04-2016 DC74_RS06845 4c0cc17f78b545e8347c07d126e35cdc 902 PANTHER PTHR16305 750 808 6.5E-18 T 23-04-2016 DC74_RS06845 4c0cc17f78b545e8347c07d126e35cdc 902 Pfam PF00196 Bacterial regulatory proteins, luxR family 838 889 1.8E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06845 4c0cc17f78b545e8347c07d126e35cdc 902 Pfam PF13191 AAA ATPase domain 2 140 7.2E-18 T 23-04-2016 DC74_RS06845 4c0cc17f78b545e8347c07d126e35cdc 902 Gene3D G3DSA:1.10.10.10 833 889 7.5E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06845 4c0cc17f78b545e8347c07d126e35cdc 902 SUPERFAMILY SSF52540 5 208 1.66E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06845 4c0cc17f78b545e8347c07d126e35cdc 902 SUPERFAMILY SSF46894 830 889 8.16E-14 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS06845 4c0cc17f78b545e8347c07d126e35cdc 902 SMART SM00421 836 893 4.9E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 PANTHER PTHR23115 7 182 0.0 T 23-04-2016 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 PANTHER PTHR23115 266 294 0.0 T 23-04-2016 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 PANTHER PTHR23115 315 703 0.0 T 23-04-2016 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 184 2.2E-33 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 Pfam PF03764 Elongation factor G, domain IV 491 610 1.3E-48 T 23-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 Gene3D G3DSA:3.30.230.10 496 608 3.7E-48 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 Gene3D G3DSA:3.30.70.240 609 703 1.8E-34 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 23-04-2016 IPR031157 Tr-type G domain, conserved site DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 SUPERFAMILY SSF52540 7 293 8.88E-103 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 PANTHER PTHR23115:SF66 7 182 0.0 T 23-04-2016 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 PANTHER PTHR23115:SF66 266 294 0.0 T 23-04-2016 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 PANTHER PTHR23115:SF66 315 703 0.0 T 23-04-2016 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 Pfam PF00679 Elongation factor G C-terminus 613 698 3.2E-30 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 Gene3D G3DSA:3.30.70.870 417 492 2.4E-38 T 23-04-2016 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 Pfam PF03144 Elongation factor Tu domain 2 336 403 6.4E-16 T 23-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 SUPERFAMILY SSF54211 491 611 1.54E-41 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 Gene3D G3DSA:3.40.50.300 7 298 9.9E-104 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 TIGRFAM TIGR00484 EF-G: translation elongation factor G 5 704 0.0 T 23-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 Hamap MF_00054_B Elongation factor G [fusA]. 7 703 110.027 T 23-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 SUPERFAMILY SSF50447 276 416 2.59E-36 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 SMART SM00838 612 699 6.6E-59 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 Pfam PF14492 Elongation Factor G, domain II 416 490 3.3E-34 T 23-04-2016 IPR009022 Elongation factor G, III-V domain DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.1E-16 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.1E-16 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.1E-16 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.1E-16 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 PRINTS PR00315 GTP-binding elongation factor signature 59 67 4.1E-16 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 SMART SM00889 492 610 4.2E-73 T 23-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 Pfam PF00009 Elongation factor Tu GTP binding domain 10 293 1.3E-65 T 23-04-2016 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 Gene3D G3DSA:2.40.30.10 317 416 1.4E-38 T 23-04-2016 DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 SUPERFAMILY SSF54980 615 702 1.44E-30 T 23-04-2016 IPR009022 Elongation factor G, III-V domain DC74_RS18750 17c83748f1d5f08719d54bb5bb5ec3d2 706 SUPERFAMILY SSF54980 416 493 6.12E-25 T 23-04-2016 IPR009022 Elongation factor G, III-V domain DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 Gene3D G3DSA:3.30.390.30 337 409 3.5E-19 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 PANTHER PTHR22912:SF180 9 432 1.9E-89 T 23-04-2016 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 Pfam PF14759 Reductase C-terminal 337 408 5.7E-11 T 23-04-2016 IPR028202 Reductase, C-terminal DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 4.6E-12 T 23-04-2016 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 283 290 4.6E-12 T 23-04-2016 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 237 251 4.6E-12 T 23-04-2016 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 4.6E-12 T 23-04-2016 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 SUPERFAMILY SSF51905 8 322 4.24E-41 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 SUPERFAMILY SSF55424 329 409 3.85E-20 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 314 2.1E-44 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 Gene3D G3DSA:3.50.50.60 107 322 2.8E-39 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 2.0E-12 T 23-04-2016 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 2.0E-12 T 23-04-2016 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 2.0E-12 T 23-04-2016 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.0E-12 T 23-04-2016 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 PANTHER PTHR22912 9 432 1.9E-89 T 23-04-2016 DC74_RS03965 da72036f2df47d5a09fc38f69032e413 455 Gene3D G3DSA:3.50.50.60 9 106 5.4E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS34655 651e7e83e46aad8da0cdee255a1f18ab 102 PRINTS PR00155 Amicyanin family signature 29 48 1.8E-10 T 23-04-2016 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 DC74_RS34655 651e7e83e46aad8da0cdee255a1f18ab 102 PRINTS PR00155 Amicyanin family signature 69 84 1.8E-10 T 23-04-2016 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 DC74_RS34655 651e7e83e46aad8da0cdee255a1f18ab 102 PRINTS PR00155 Amicyanin family signature 85 100 1.8E-10 T 23-04-2016 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 DC74_RS34655 651e7e83e46aad8da0cdee255a1f18ab 102 PANTHER PTHR36507:SF1 21 102 1.2E-22 T 23-04-2016 DC74_RS34655 651e7e83e46aad8da0cdee255a1f18ab 102 Pfam PF13473 Cupredoxin-like domain 20 98 7.6E-10 T 23-04-2016 IPR028096 EfeO-type cupredoxin-like domain DC74_RS34655 651e7e83e46aad8da0cdee255a1f18ab 102 PANTHER PTHR36507 21 102 1.2E-22 T 23-04-2016 DC74_RS34655 651e7e83e46aad8da0cdee255a1f18ab 102 Gene3D G3DSA:2.60.40.420 11 101 2.8E-26 T 23-04-2016 IPR008972 Cupredoxin DC74_RS34655 651e7e83e46aad8da0cdee255a1f18ab 102 SUPERFAMILY SSF49503 10 100 1.47E-24 T 23-04-2016 IPR008972 Cupredoxin DC74_RS10485 0fa4458b40020e35de1ad1ed1d35edb0 349 Gene3D G3DSA:3.20.20.30 1 337 2.1E-76 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10485 0fa4458b40020e35de1ad1ed1d35edb0 349 PANTHER PTHR30011 12 337 5.6E-161 T 23-04-2016 DC74_RS10485 0fa4458b40020e35de1ad1ed1d35edb0 349 PANTHER PTHR30011:SF4 12 337 5.6E-161 T 23-04-2016 DC74_RS10485 0fa4458b40020e35de1ad1ed1d35edb0 349 Pfam PF00296 Luciferase-like monooxygenase 17 318 1.5E-79 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10485 0fa4458b40020e35de1ad1ed1d35edb0 349 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 322 2.4E-116 T 23-04-2016 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- DC74_RS10485 0fa4458b40020e35de1ad1ed1d35edb0 349 SUPERFAMILY SSF51679 1 337 2.36E-70 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS26930 178dc4681c22d6a67b0126f2f2274c35 271 Pfam PF00213 ATP synthase delta (OSCP) subunit 109 268 2.3E-33 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 DC74_RS26930 178dc4681c22d6a67b0126f2f2274c35 271 Gene3D G3DSA:1.10.520.20 110 197 2.8E-5 T 23-04-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain DC74_RS26930 178dc4681c22d6a67b0126f2f2274c35 271 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 231 250 - T 23-04-2016 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 DC74_RS26930 178dc4681c22d6a67b0126f2f2274c35 271 PRINTS PR00125 ATP synthase delta subunit signature 244 262 5.5E-7 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 DC74_RS26930 178dc4681c22d6a67b0126f2f2274c35 271 PRINTS PR00125 ATP synthase delta subunit signature 229 244 5.5E-7 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 DC74_RS26930 178dc4681c22d6a67b0126f2f2274c35 271 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 111 268 3.9E-21 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 DC74_RS26930 178dc4681c22d6a67b0126f2f2274c35 271 PANTHER PTHR11910 110 270 1.3E-34 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 DC74_RS26930 178dc4681c22d6a67b0126f2f2274c35 271 Hamap MF_01416 ATP synthase subunit delta [atpD]. 87 271 15.237 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 DC74_RS26930 178dc4681c22d6a67b0126f2f2274c35 271 SUPERFAMILY SSF47928 110 198 3.01E-5 T 23-04-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 189 4.0E-5 T 23-04-2016 DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 SUPERFAMILY SSF51735 9 244 1.85E-68 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 PANTHER PTHR24322 14 138 1.5E-36 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 PANTHER PTHR24322 154 184 1.5E-36 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 Gene3D G3DSA:3.40.50.720 6 244 2.1E-72 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.7E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 6.7E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 6.7E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.7E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 6.7E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.7E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 6.4E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 6.4E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 6.4E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36380 e7189f6c357cc3a78d00e72373189d3f 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 244 2.3E-51 T 23-04-2016 DC74_RS05025 79a94ab3ddae36f605038716af50dea2 530 SUPERFAMILY SSF51645 9 521 4.45E-169 T 23-04-2016 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 DC74_RS05025 79a94ab3ddae36f605038716af50dea2 530 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 23 519 1.8E-211 T 23-04-2016 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 DC74_RS05025 79a94ab3ddae36f605038716af50dea2 530 PANTHER PTHR21631:SF1 1 527 4.1E-248 T 23-04-2016 DC74_RS05025 79a94ab3ddae36f605038716af50dea2 530 Gene3D G3DSA:1.20.1220.12 415 514 1.4E-25 T 23-04-2016 DC74_RS05025 79a94ab3ddae36f605038716af50dea2 530 ProSitePatterns PS00510 Malate synthase signature. 266 281 - T 23-04-2016 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 DC74_RS05025 79a94ab3ddae36f605038716af50dea2 530 PIRSF PIRSF001363 1 523 9.9E-225 T 23-04-2016 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 DC74_RS05025 79a94ab3ddae36f605038716af50dea2 530 PANTHER PTHR21631 1 527 4.1E-248 T 23-04-2016 DC74_RS05025 79a94ab3ddae36f605038716af50dea2 530 Gene3D G3DSA:3.20.20.360 73 408 3.2E-113 T 23-04-2016 DC74_RS05025 79a94ab3ddae36f605038716af50dea2 530 Pfam PF01274 Malate synthase 14 519 1.7E-172 T 23-04-2016 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 DC74_RS13530 98983d99e47a122106a02c01fab9dfed 494 PANTHER PTHR23355 29 232 4.0E-41 T 23-04-2016 DC74_RS13530 98983d99e47a122106a02c01fab9dfed 494 SUPERFAMILY SSF50249 22 427 2.68E-85 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS13530 98983d99e47a122106a02c01fab9dfed 494 Pfam PF00773 RNB domain 65 374 1.3E-43 T 23-04-2016 DC74_RS13530 98983d99e47a122106a02c01fab9dfed 494 SMART SM00955 63 383 7.8E-56 T 23-04-2016 DC74_RS10450 cb80f46b973cf40755e1858975bb9a8b 443 PANTHER PTHR13794 188 443 4.7E-172 T 23-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 DC74_RS10450 cb80f46b973cf40755e1858975bb9a8b 443 PANTHER PTHR13794 4 152 4.7E-172 T 23-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 DC74_RS10450 cb80f46b973cf40755e1858975bb9a8b 443 SUPERFAMILY SSF54826 6 140 6.19E-34 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS10450 cb80f46b973cf40755e1858975bb9a8b 443 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 246 277 - T 23-04-2016 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 DC74_RS10450 cb80f46b973cf40755e1858975bb9a8b 443 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 38 137 5.3E-9 T 23-04-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain DC74_RS10450 cb80f46b973cf40755e1858975bb9a8b 443 Pfam PF13378 Enolase C-terminal domain-like 203 416 5.2E-62 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS10450 cb80f46b973cf40755e1858975bb9a8b 443 Gene3D G3DSA:3.20.20.120 183 426 1.1E-89 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS10450 cb80f46b973cf40755e1858975bb9a8b 443 SUPERFAMILY SSF51604 185 430 1.1E-67 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS10450 cb80f46b973cf40755e1858975bb9a8b 443 PANTHER PTHR13794:SF58 188 443 4.7E-172 T 23-04-2016 DC74_RS10450 cb80f46b973cf40755e1858975bb9a8b 443 PANTHER PTHR13794:SF58 4 152 4.7E-172 T 23-04-2016 DC74_RS10450 cb80f46b973cf40755e1858975bb9a8b 443 Gene3D G3DSA:3.30.390.10 6 179 6.8E-75 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS10450 cb80f46b973cf40755e1858975bb9a8b 443 SMART SM00922 200 296 5.9E-25 T 23-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DC74_RS19340 5bc8a7d7a275aff04a3e1eff80e0f20d 176 SUPERFAMILY SSF51182 13 168 1.72E-40 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS19340 5bc8a7d7a275aff04a3e1eff80e0f20d 176 Pfam PF06172 Cupin superfamily (DUF985) 14 152 1.1E-35 T 23-04-2016 IPR009327 Cupin domain of unknown function DUF985 DC74_RS19340 5bc8a7d7a275aff04a3e1eff80e0f20d 176 Gene3D G3DSA:2.60.120.10 8 174 1.5E-43 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS19340 5bc8a7d7a275aff04a3e1eff80e0f20d 176 PANTHER PTHR33387:SF3 1 175 8.1E-41 T 23-04-2016 DC74_RS19340 5bc8a7d7a275aff04a3e1eff80e0f20d 176 PANTHER PTHR33387 1 175 8.1E-41 T 23-04-2016 DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 Pfam PF13185 GAF domain 415 508 7.0E-9 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 SMART SM00065 340 517 3.1E-6 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 SUPERFAMILY SSF55781 420 518 3.27E-15 T 23-04-2016 IPR029016 GAF domain-like DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 Gene3D G3DSA:3.30.450.40 338 515 6.4E-32 T 23-04-2016 IPR029016 GAF domain-like DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 SMART SM00331 542 766 2.0E-29 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 SUPERFAMILY SSF55874 811 888 8.32E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 Pfam PF13581 Histidine kinase-like ATPase domain 779 887 6.8E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 PANTHER PTHR21021:SF19 459 619 5.6E-63 T 23-04-2016 DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 PANTHER PTHR21021:SF19 635 775 5.6E-63 T 23-04-2016 DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 Pfam PF17203 Single cache domain 3 45 177 7.2E-25 T 23-04-2016 IPR033463 Single cache domain 3 DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 SUPERFAMILY SSF103190 49 177 9.42E-32 T 23-04-2016 IPR029151 Periplasmic sensor domain-like DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 PANTHER PTHR21021 459 619 5.6E-63 T 23-04-2016 DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 PANTHER PTHR21021 635 775 5.6E-63 T 23-04-2016 DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 SUPERFAMILY SSF81606 555 766 4.45E-12 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 568 766 1.2E-52 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS36005 607dfe6ab4c1e2367fa65a94a6c2a5f8 907 Gene3D G3DSA:3.30.450.20 41 178 5.5E-42 T 23-04-2016 DC74_RS26145 099398b907853940ee03bda5d6344e0f 319 PANTHER PTHR10366:SF427 274 312 5.5E-91 T 23-04-2016 DC74_RS26145 099398b907853940ee03bda5d6344e0f 319 PANTHER PTHR10366:SF427 2 252 5.5E-91 T 23-04-2016 DC74_RS26145 099398b907853940ee03bda5d6344e0f 319 Gene3D G3DSA:3.90.25.10 282 311 5.7E-5 T 23-04-2016 DC74_RS26145 099398b907853940ee03bda5d6344e0f 319 Gene3D G3DSA:3.90.25.10 184 201 5.7E-5 T 23-04-2016 DC74_RS26145 099398b907853940ee03bda5d6344e0f 319 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 222 2.7E-32 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS26145 099398b907853940ee03bda5d6344e0f 319 Gene3D G3DSA:3.40.50.720 1 160 2.2E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26145 099398b907853940ee03bda5d6344e0f 319 Gene3D G3DSA:3.40.50.720 202 241 2.2E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26145 099398b907853940ee03bda5d6344e0f 319 SUPERFAMILY SSF51735 283 312 3.56E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26145 099398b907853940ee03bda5d6344e0f 319 SUPERFAMILY SSF51735 1 256 3.56E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26145 099398b907853940ee03bda5d6344e0f 319 PANTHER PTHR10366 274 312 5.5E-91 T 23-04-2016 DC74_RS26145 099398b907853940ee03bda5d6344e0f 319 PANTHER PTHR10366 2 252 5.5E-91 T 23-04-2016 DC74_RS11790 5565ca1a846b09fa3954caae66a7f650 349 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 1 300 1.0E-97 T 23-04-2016 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA DC74_RS11790 5565ca1a846b09fa3954caae66a7f650 349 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 51 299 5.4E-84 T 23-04-2016 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA DC74_RS11790 5565ca1a846b09fa3954caae66a7f650 349 PANTHER PTHR38658:SF1 1 312 3.6E-96 T 23-04-2016 DC74_RS11790 5565ca1a846b09fa3954caae66a7f650 349 PANTHER PTHR38658 1 312 3.6E-96 T 23-04-2016 DC74_RS04400 67e5b90d466f49b088c9ef92ab0b726e 429 SMART SM00382 194 329 7.1E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS04400 67e5b90d466f49b088c9ef92ab0b726e 429 Pfam PF00583 Acetyltransferase (GNAT) family 51 105 1.5E-5 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS04400 67e5b90d466f49b088c9ef92ab0b726e 429 SUPERFAMILY SSF55729 3 105 1.51E-12 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS04400 67e5b90d466f49b088c9ef92ab0b726e 429 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 199 325 2.1E-24 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS04400 67e5b90d466f49b088c9ef92ab0b726e 429 Gene3D G3DSA:3.40.630.30 5 105 2.1E-14 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS04400 67e5b90d466f49b088c9ef92ab0b726e 429 PANTHER PTHR23077 160 381 2.3E-41 T 23-04-2016 DC74_RS04400 67e5b90d466f49b088c9ef92ab0b726e 429 SUPERFAMILY SSF52540 155 379 1.18E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04400 67e5b90d466f49b088c9ef92ab0b726e 429 Gene3D G3DSA:3.40.50.300 156 361 7.3E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04400 67e5b90d466f49b088c9ef92ab0b726e 429 ProSitePatterns PS00674 AAA-protein family signature. 297 315 - T 23-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DC74_RS39575 556850a5b48ddc1bba0a5d9a5bd42d57 380 PANTHER PTHR13833 56 360 1.9E-55 T 23-04-2016 DC74_RS39575 556850a5b48ddc1bba0a5d9a5bd42d57 380 SUPERFAMILY SSF50974 143 377 3.14E-24 T 23-04-2016 IPR011045 Nitrous oxide reductase, N-terminal DC74_RS39575 556850a5b48ddc1bba0a5d9a5bd42d57 380 Gene3D G3DSA:2.130.10.10 242 372 2.0E-12 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS39575 556850a5b48ddc1bba0a5d9a5bd42d57 380 PANTHER PTHR13833:SF51 56 360 1.9E-55 T 23-04-2016 DC74_RS39575 556850a5b48ddc1bba0a5d9a5bd42d57 380 SUPERFAMILY SSF63829 50 162 6.98E-10 T 23-04-2016 DC74_RS39575 556850a5b48ddc1bba0a5d9a5bd42d57 380 Gene3D G3DSA:2.130.10.10 46 214 1.0E-19 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 Pfam PF12848 ABC transporter 198 265 6.3E-8 T 23-04-2016 IPR032781 ABC-transporter extension domain DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 Gene3D G3DSA:3.40.50.300 289 488 2.1E-40 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 Gene3D G3DSA:3.40.50.300 7 251 4.3E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 PANTHER PTHR19211 1 543 0.0 T 23-04-2016 DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 SMART SM00382 30 213 6.9E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 SMART SM00382 315 491 6.9E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 Pfam PF00005 ABC transporter 21 159 3.5E-22 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 Pfam PF00005 ABC transporter 306 447 2.1E-19 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 SUPERFAMILY SSF52540 281 489 3.31E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 Pfam PF16326 ABC transporter C-terminal domain 536 598 1.0E-9 T 23-04-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 SUPERFAMILY SSF52540 6 208 4.0E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 ProSitePatterns PS00211 ABC transporters family signature. 419 433 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS17580 34918ead51bb285091914b5a9a2d4e3a 600 PANTHER PTHR19211:SF55 1 543 0.0 T 23-04-2016 DC74_RS22775 6a7a85e37ea6b0e5d9eb77ab9a5e3c39 345 Pfam PF00579 tRNA synthetases class I (W and Y) 11 295 4.6E-63 T 23-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS22775 6a7a85e37ea6b0e5d9eb77ab9a5e3c39 345 Gene3D G3DSA:3.40.50.620 11 226 1.3E-74 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS22775 6a7a85e37ea6b0e5d9eb77ab9a5e3c39 345 SUPERFAMILY SSF52374 13 340 1.83E-75 T 23-04-2016 DC74_RS22775 6a7a85e37ea6b0e5d9eb77ab9a5e3c39 345 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 12 340 1.5E-90 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 DC74_RS22775 6a7a85e37ea6b0e5d9eb77ab9a5e3c39 345 Gene3D G3DSA:1.10.240.10 227 330 2.6E-11 T 23-04-2016 DC74_RS22775 6a7a85e37ea6b0e5d9eb77ab9a5e3c39 345 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 20 29 - T 23-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS22775 6a7a85e37ea6b0e5d9eb77ab9a5e3c39 345 PANTHER PTHR10055:SF10 13 344 1.9E-146 T 23-04-2016 DC74_RS22775 6a7a85e37ea6b0e5d9eb77ab9a5e3c39 345 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 11 341 35.815 T 23-04-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2 DC74_RS22775 6a7a85e37ea6b0e5d9eb77ab9a5e3c39 345 PANTHER PTHR10055 13 344 1.9E-146 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 DC74_RS22775 6a7a85e37ea6b0e5d9eb77ab9a5e3c39 345 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 24 40 1.2E-19 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 DC74_RS22775 6a7a85e37ea6b0e5d9eb77ab9a5e3c39 345 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 152 173 1.2E-19 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 DC74_RS22775 6a7a85e37ea6b0e5d9eb77ab9a5e3c39 345 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 75 94 1.2E-19 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 DC74_RS37620 3663ee0fb64805159df16ad7f8d3381d 424 PANTHER PTHR30521:SF4 49 424 6.4E-129 T 23-04-2016 DC74_RS37620 3663ee0fb64805159df16ad7f8d3381d 424 Pfam PF04261 Dyp-type peroxidase family 66 410 5.0E-104 T 23-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- DC74_RS37620 3663ee0fb64805159df16ad7f8d3381d 424 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 15 421 2.0E-141 T 23-04-2016 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 KEGG: 00480+1.11.1.- DC74_RS37620 3663ee0fb64805159df16ad7f8d3381d 424 SUPERFAMILY SSF54909 59 416 6.61E-92 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS37620 3663ee0fb64805159df16ad7f8d3381d 424 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 66 410 5.2E-95 T 23-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- DC74_RS37620 3663ee0fb64805159df16ad7f8d3381d 424 PANTHER PTHR30521 49 424 6.4E-129 T 23-04-2016 DC74_RS26790 76462ea47916748b879e1dda4acfa74b 287 Pfam PF12697 Alpha/beta hydrolase family 53 270 3.5E-15 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS26790 76462ea47916748b879e1dda4acfa74b 287 SUPERFAMILY SSF53474 24 286 2.43E-35 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS26790 76462ea47916748b879e1dda4acfa74b 287 PANTHER PTHR10992 24 287 3.7E-32 T 23-04-2016 DC74_RS26790 76462ea47916748b879e1dda4acfa74b 287 Gene3D G3DSA:3.40.50.1820 6 285 7.1E-43 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS26790 76462ea47916748b879e1dda4acfa74b 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 7.3E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS26790 76462ea47916748b879e1dda4acfa74b 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 136 149 7.3E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS26790 76462ea47916748b879e1dda4acfa74b 287 PANTHER PTHR10992:SF771 24 287 3.7E-32 T 23-04-2016 DC74_RS36020 736c0e981ff1c49224ca63372b56518a 360 PANTHER PTHR30004 20 356 2.9E-122 T 23-04-2016 DC74_RS36020 736c0e981ff1c49224ca63372b56518a 360 Gene3D G3DSA:3.40.718.10 21 342 7.9E-108 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS36020 736c0e981ff1c49224ca63372b56518a 360 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 20 344 31.736 T 23-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 DC74_RS36020 736c0e981ff1c49224ca63372b56518a 360 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 55 340 1.1E-87 T 23-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 DC74_RS36020 736c0e981ff1c49224ca63372b56518a 360 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 24 342 7.4E-95 T 23-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 DC74_RS36020 736c0e981ff1c49224ca63372b56518a 360 SUPERFAMILY SSF53659 22 343 4.07E-93 T 23-04-2016 DC74_RS36020 736c0e981ff1c49224ca63372b56518a 360 PANTHER PTHR30004:SF6 20 356 2.9E-122 T 23-04-2016 DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 Gene3D G3DSA:3.30.200.20 4 94 1.1E-29 T 23-04-2016 DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 PANTHER PTHR24362 1 287 1.0E-116 T 23-04-2016 DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 Pfam PF00069 Protein kinase domain 11 265 1.5E-51 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 Pfam PF03793 PASTA domain 514 576 4.1E-15 T 23-04-2016 IPR005543 PASTA domain DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 Pfam PF03793 PASTA domain 446 508 3.9E-14 T 23-04-2016 IPR005543 PASTA domain DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 Pfam PF03793 PASTA domain 582 642 4.3E-9 T 23-04-2016 IPR005543 PASTA domain DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 Pfam PF03793 PASTA domain 379 439 5.9E-12 T 23-04-2016 IPR005543 PASTA domain DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 SMART SM00220 11 277 5.8E-69 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 SMART SM00740 509 576 2.6E-18 T 23-04-2016 IPR005543 PASTA domain DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 SMART SM00740 442 508 2.7E-12 T 23-04-2016 IPR005543 PASTA domain DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 SMART SM00740 374 441 1.2E-12 T 23-04-2016 IPR005543 PASTA domain DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 SMART SM00740 577 644 5.0E-11 T 23-04-2016 IPR005543 PASTA domain DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 SUPERFAMILY SSF56112 7 273 1.21E-78 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 SUPERFAMILY SSF54184 378 439 1.44E-5 T 23-04-2016 DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 PANTHER PTHR24362:SF160 1 287 1.0E-116 T 23-04-2016 DC74_RS20570 34c076d2ba7b5ba8e5a2724b394557ef 666 Gene3D G3DSA:1.10.510.10 98 274 6.0E-50 T 23-04-2016 DC74_RS25960 899f43d15a298dfefcd93112934de03a 201 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 13 192 5.1E-70 T 23-04-2016 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 DC74_RS25960 899f43d15a298dfefcd93112934de03a 201 SUPERFAMILY SSF48150 12 194 3.3E-65 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS25960 899f43d15a298dfefcd93112934de03a 201 Pfam PF03352 Methyladenine glycosylase 24 191 6.4E-66 T 23-04-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 DC74_RS25960 899f43d15a298dfefcd93112934de03a 201 Gene3D G3DSA:1.10.340.30 12 193 1.9E-69 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS25960 899f43d15a298dfefcd93112934de03a 201 PANTHER PTHR30037 1 198 1.5E-95 T 23-04-2016 DC74_RS25960 899f43d15a298dfefcd93112934de03a 201 PANTHER PTHR30037:SF4 1 198 1.5E-95 T 23-04-2016 DC74_RS38310 1b4288a47d900bb446afb581a5c4a789 221 Gene3D G3DSA:1.10.3720.10 11 218 6.9E-28 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38310 1b4288a47d900bb446afb581a5c4a789 221 PANTHER PTHR30450 1 221 6.7E-90 T 23-04-2016 DC74_RS38310 1b4288a47d900bb446afb581a5c4a789 221 SUPERFAMILY SSF161098 10 204 2.22E-33 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38310 1b4288a47d900bb446afb581a5c4a789 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 218 2.9E-11 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38310 1b4288a47d900bb446afb581a5c4a789 221 PANTHER PTHR30450:SF3 1 221 6.7E-90 T 23-04-2016 DC74_RS17860 ebd62063f32f6d128f76f9386c65b301 504 Gene3D G3DSA:3.30.70.1450 395 452 7.3E-7 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 DC74_RS17860 ebd62063f32f6d128f76f9386c65b301 504 PANTHER PTHR32507:SF7 1 474 1.5E-192 T 23-04-2016 IPR030151 K(+)/H(+) antiporter NhaP GO:0005451|GO:0006813|GO:0016021 DC74_RS17860 ebd62063f32f6d128f76f9386c65b301 504 SUPERFAMILY SSF116726 389 459 1.7E-10 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 DC74_RS17860 ebd62063f32f6d128f76f9386c65b301 504 PANTHER PTHR32507 1 474 1.5E-192 T 23-04-2016 DC74_RS17860 ebd62063f32f6d128f76f9386c65b301 504 Pfam PF00999 Sodium/hydrogen exchanger family 6 365 7.3E-48 T 23-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 DC74_RS17860 ebd62063f32f6d128f76f9386c65b301 504 Pfam PF02080 TrkA-C domain 397 450 1.4E-10 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 PANTHER PTHR13812 1 448 4.4E-83 T 23-04-2016 DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 PANTHER PTHR13812:SF18 1 448 4.4E-83 T 23-04-2016 DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 Gene3D G3DSA:3.40.50.720 183 319 7.0E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 184 319 1.6E-25 T 23-04-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 429 25.352 T 23-04-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 SUPERFAMILY SSF69075 330 432 9.29E-16 T 23-04-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 432 3.0E-112 T 23-04-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 332 431 5.8E-20 T 23-04-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 PIRSF PIRSF000445 1 445 4.3E-133 T 23-04-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 SUPERFAMILY SSF51735 179 317 1.97E-19 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 23-04-2016 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 SUPERFAMILY SSF69742 1 158 3.92E-45 T 23-04-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 DC74_RS19445 d3941137954959e4653e3ceae0a2b279 456 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 1.3E-44 T 23-04-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.50.720 3248 3432 9.4E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF08659 KR domain 1734 1912 2.7E-60 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF08659 KR domain 3248 3425 1.8E-59 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM01294 2019 2086 1.5E-5 T 23-04-2016 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM01294 3532 3599 4.7E-8 T 23-04-2016 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.47.10 40 300 7.9E-88 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF53901 2108 2480 3.32E-103 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF47336 2014 2126 2.09E-25 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM00823 Phosphopantetheine attachment site 2018 2090 4.8E-33 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM00823 Phosphopantetheine attachment site 3531 3603 2.6E-30 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF53901 3622 3995 3.85E-103 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.50.720 1733 1916 3.3E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.50.720 1554 1651 1.3E-18 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1441 1496 2.5E-5 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF47336 3529 3640 1.14E-23 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1549 1570 - T 23-04-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF53901 35 408 1.41E-100 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF51735 1520 1663 1.38E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM00825 Beta-ketoacyl synthase 40 464 6.2E-211 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM00825 Beta-ketoacyl synthase 2113 2535 6.2E-215 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM00825 Beta-ketoacyl synthase 3627 4050 3.6E-215 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM00826 928 1091 4.1E-81 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4000 4058 8.7E-10 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 530 6.4E-15 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2485 2584 2.0E-16 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF51735 3032 3236 5.68E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 571 861 1.3E-122 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2626 2924 9.2E-109 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF51735 1210 1399 7.09E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 PANTHER PTHR11712:SF242 10 2086 0.0 T 23-04-2016 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 PANTHER PTHR11712:SF242 4016 4033 0.0 T 23-04-2016 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF14765 Polyketide synthase dehydratase 928 1198 3.4E-57 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF00550 Phosphopantetheine attachment site 3533 3599 2.4E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF00550 Phosphopantetheine attachment site 2020 2086 6.4E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 201 217 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3785 3801 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2270 2286 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:1.10.1200.10 3529 3604 4.0E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:1.10.1200.10 2017 2090 6.9E-23 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.366.10 566 689 1.7E-77 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.366.10 755 864 1.7E-77 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.366.10 2816 2927 2.4E-79 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.366.10 2621 2750 2.4E-79 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.47.10 3623 3884 4.6E-91 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.47.10 2108 2369 3.3E-89 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.47.10 301 464 1.2E-65 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.47.10 3885 4050 1.2E-65 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.40.47.10 2370 2535 2.4E-67 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF52151 2817 2920 7.59E-73 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF52151 2622 2756 7.59E-73 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF55048 2755 2816 5.36E-11 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 PANTHER PTHR11712 10 2086 0.0 T 23-04-2016 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 PANTHER PTHR11712 4016 4033 0.0 T 23-04-2016 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM00829 1421 1724 1.3E-170 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF51735 3244 3460 6.5E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3625 3872 9.0E-88 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2111 2357 5.3E-84 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 38 288 1.6E-86 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF52151 748 858 1.6E-73 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF52151 568 689 1.6E-73 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF55048 694 755 6.67E-13 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1734 1914 1.3E-65 T 23-04-2016 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3248 3427 6.9E-56 T 23-04-2016 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2045 2060 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3558 3573 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3880 3997 1.3E-45 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2365 2482 2.0E-45 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 296 411 2.4E-44 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF51735 1730 1927 1.53E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.30.70.250 2755 2815 1.7E-7 T 23-04-2016 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.30.70.250 695 754 5.8E-9 T 23-04-2016 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF00107 Zinc-binding dehydrogenase 1560 1652 7.0E-15 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 SUPERFAMILY SSF50129 1433 1554 5.5E-27 T 23-04-2016 IPR011032 GroES-like DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF00698 Acyl transferase domain 2626 2943 3.6E-61 T 23-04-2016 IPR014043 Acyl transferase DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Pfam PF00698 Acyl transferase domain 571 879 1.2E-59 T 23-04-2016 IPR014043 Acyl transferase DC74_RS38705 fb382187a6bb80d0f9604d278e843d34 4191 Gene3D G3DSA:3.90.180.10 1430 1553 1.7E-41 T 23-04-2016 IPR011032 GroES-like DC74_RS35840 be51676ff27985a23c4e9936ab455358 359 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 229 307 2.3E-24 T 23-04-2016 IPR027394 Cytochrome-c3 hydrogenase, C-terminal DC74_RS35840 be51676ff27985a23c4e9936ab455358 359 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 186 209 1.3E-7 T 23-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 DC74_RS35840 be51676ff27985a23c4e9936ab455358 359 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 253 279 1.3E-7 T 23-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 DC74_RS35840 be51676ff27985a23c4e9936ab455358 359 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 135 149 1.3E-7 T 23-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 DC74_RS35840 be51676ff27985a23c4e9936ab455358 359 Gene3D G3DSA:3.40.50.700 20 227 9.4E-44 T 23-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 DC74_RS35840 be51676ff27985a23c4e9936ab455358 359 PIRSF PIRSF000310 1 358 2.9E-92 T 23-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 DC74_RS35840 be51676ff27985a23c4e9936ab455358 359 Gene3D G3DSA:4.10.480.10 229 308 6.3E-27 T 23-04-2016 IPR027394 Cytochrome-c3 hydrogenase, C-terminal DC74_RS35840 be51676ff27985a23c4e9936ab455358 359 SUPERFAMILY SSF56770 22 308 7.59E-65 T 23-04-2016 DC74_RS35840 be51676ff27985a23c4e9936ab455358 359 PANTHER PTHR30013 17 309 8.9E-48 T 23-04-2016 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 DC74_RS35840 be51676ff27985a23c4e9936ab455358 359 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 33 206 6.9E-26 T 23-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 DC74_RS19540 25926285385724ce824721332f8f9b5f 454 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 340 2.4E-36 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19540 25926285385724ce824721332f8f9b5f 454 Gene3D G3DSA:3.50.50.60 3 118 3.2E-18 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19540 25926285385724ce824721332f8f9b5f 454 PANTHER PTHR10632:SF8 3 149 4.4E-15 T 23-04-2016 DC74_RS19540 25926285385724ce824721332f8f9b5f 454 SUPERFAMILY SSF51905 181 400 1.22E-17 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19540 25926285385724ce824721332f8f9b5f 454 SUPERFAMILY SSF51905 3 62 1.22E-17 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19540 25926285385724ce824721332f8f9b5f 454 PANTHER PTHR10632 3 149 4.4E-15 T 23-04-2016 DC74_RS19540 25926285385724ce824721332f8f9b5f 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 6.2E-10 T 23-04-2016 DC74_RS19540 25926285385724ce824721332f8f9b5f 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 6.2E-10 T 23-04-2016 DC74_RS19540 25926285385724ce824721332f8f9b5f 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 128 6.2E-10 T 23-04-2016 DC74_RS19540 25926285385724ce824721332f8f9b5f 454 Gene3D G3DSA:3.50.50.60 119 352 1.3E-23 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19540 25926285385724ce824721332f8f9b5f 454 SUPERFAMILY SSF51905 3 219 8.64E-24 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 SMART SM00382 99 303 4.7E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 448 33.368 T 23-04-2016 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 SMART SM00962 100 298 7.1E-106 T 23-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 430 2.0E-172 T 23-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 SUPERFAMILY SSF52540 42 358 2.05E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 8.2E-21 T 23-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 PANTHER PTHR11564:SF7 1 436 3.5E-239 T 23-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 Gene3D G3DSA:1.10.260.30 331 433 3.2E-37 T 23-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 SUPERFAMILY SSF47446 331 432 4.25E-33 T 23-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 Pfam PF02978 Signal peptide binding domain 331 429 4.9E-31 T 23-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 PANTHER PTHR11564 1 436 3.5E-239 T 23-04-2016 DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 Gene3D G3DSA:3.40.50.300 94 299 1.1E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 Gene3D G3DSA:1.20.120.140 2 89 1.4E-33 T 23-04-2016 DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 1.7E-67 T 23-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 DC74_RS28095 759ad230196c1b5c29a9516b8336499e 517 SMART SM00963 1 86 6.4E-33 T 23-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 DC74_RS32695 b99d6ab7efcc478ff96e9a1db3feaa07 260 PANTHER PTHR12905 10 226 1.7E-37 T 23-04-2016 DC74_RS32695 b99d6ab7efcc478ff96e9a1db3feaa07 260 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 9 257 34.612 T 23-04-2016 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 DC74_RS32695 b99d6ab7efcc478ff96e9a1db3feaa07 260 Gene3D G3DSA:3.60.21.10 11 227 2.0E-37 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS32695 b99d6ab7efcc478ff96e9a1db3feaa07 260 SUPERFAMILY SSF56300 11 248 1.61E-47 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS32695 b99d6ab7efcc478ff96e9a1db3feaa07 260 PANTHER PTHR12905:SF7 10 226 1.7E-37 T 23-04-2016 DC74_RS32695 b99d6ab7efcc478ff96e9a1db3feaa07 260 Pfam PF00149 Calcineurin-like phosphoesterase 11 198 1.0E-13 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS30635 b15a5ad9173c2d8f3bd4338846243b00 386 PANTHER PTHR11228:SF7 13 373 1.2E-44 T 23-04-2016 DC74_RS30635 b15a5ad9173c2d8f3bd4338846243b00 386 SUPERFAMILY SSF102114 17 342 1.57E-34 T 23-04-2016 DC74_RS30635 b15a5ad9173c2d8f3bd4338846243b00 386 Gene3D G3DSA:3.20.20.70 18 353 6.3E-39 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS30635 b15a5ad9173c2d8f3bd4338846243b00 386 PANTHER PTHR11228 13 373 1.2E-44 T 23-04-2016 DC74_RS30635 b15a5ad9173c2d8f3bd4338846243b00 386 Pfam PF04055 Radical SAM superfamily 25 177 1.2E-15 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS25350 e1a530790ad9f4fdfe63c6eef30171eb 543 SUPERFAMILY SSF51338 477 529 1.32E-20 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS25350 e1a530790ad9f4fdfe63c6eef30171eb 543 SUPERFAMILY SSF51338 1 59 1.32E-20 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS25350 e1a530790ad9f4fdfe63c6eef30171eb 543 PANTHER PTHR22935 278 543 1.4E-103 T 23-04-2016 DC74_RS25350 e1a530790ad9f4fdfe63c6eef30171eb 543 Gene3D G3DSA:3.20.20.140 401 461 2.8E-112 T 23-04-2016 DC74_RS25350 e1a530790ad9f4fdfe63c6eef30171eb 543 Gene3D G3DSA:3.20.20.140 73 296 2.8E-112 T 23-04-2016 DC74_RS25350 e1a530790ad9f4fdfe63c6eef30171eb 543 Gene3D G3DSA:2.30.40.10 462 527 1.1E-9 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS25350 e1a530790ad9f4fdfe63c6eef30171eb 543 SUPERFAMILY SSF51556 59 304 8.01E-73 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS25350 e1a530790ad9f4fdfe63c6eef30171eb 543 SUPERFAMILY SSF51556 347 477 8.01E-73 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS25350 e1a530790ad9f4fdfe63c6eef30171eb 543 Pfam PF07969 Amidohydrolase family 47 522 8.6E-62 T 23-04-2016 IPR013108 Amidohydrolase 3 DC74_RS25350 e1a530790ad9f4fdfe63c6eef30171eb 543 Gene3D G3DSA:2.30.40.10 1 72 1.9E-17 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS25350 e1a530790ad9f4fdfe63c6eef30171eb 543 PANTHER PTHR22935:SF55 278 543 1.4E-103 T 23-04-2016 DC74_RS03195 3c125832fab94b256be36c0a85a48bd5 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 153 1.1E-17 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03195 3c125832fab94b256be36c0a85a48bd5 165 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 31 62 - T 23-04-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03195 3c125832fab94b256be36c0a85a48bd5 165 Gene3D G3DSA:1.10.1740.10 4 96 1.2E-16 T 23-04-2016 DC74_RS03195 3c125832fab94b256be36c0a85a48bd5 165 Pfam PF04542 Sigma-70 region 2 10 76 5.7E-11 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03195 3c125832fab94b256be36c0a85a48bd5 165 Pfam PF08281 Sigma-70, region 4 98 150 1.4E-16 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03195 3c125832fab94b256be36c0a85a48bd5 165 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 155 1.2E-45 T 23-04-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 DC74_RS03195 3c125832fab94b256be36c0a85a48bd5 165 SUPERFAMILY SSF88946 4 72 1.26E-15 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03195 3c125832fab94b256be36c0a85a48bd5 165 PANTHER PTHR30173:SF17 4 160 2.3E-38 T 23-04-2016 DC74_RS03195 3c125832fab94b256be36c0a85a48bd5 165 Gene3D G3DSA:1.10.10.10 99 156 3.0E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03195 3c125832fab94b256be36c0a85a48bd5 165 PANTHER PTHR30173 4 160 2.3E-38 T 23-04-2016 DC74_RS03195 3c125832fab94b256be36c0a85a48bd5 165 SUPERFAMILY SSF88659 98 155 1.21E-14 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS24965 c73497d4aae632b3fb93b26634dbf04a 386 PANTHER PTHR11409:SF43 10 358 1.5E-99 T 23-04-2016 DC74_RS24965 c73497d4aae632b3fb93b26634dbf04a 386 Pfam PF00962 Adenosine/AMP deaminase 17 354 2.2E-84 T 23-04-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 DC74_RS24965 c73497d4aae632b3fb93b26634dbf04a 386 Hamap MF_00540 Adenosine deaminase [add]. 12 357 54.168 T 23-04-2016 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 DC74_RS24965 c73497d4aae632b3fb93b26634dbf04a 386 Gene3D G3DSA:3.20.20.140 14 356 7.6E-103 T 23-04-2016 DC74_RS24965 c73497d4aae632b3fb93b26634dbf04a 386 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 18 354 1.6E-70 T 23-04-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 DC74_RS24965 c73497d4aae632b3fb93b26634dbf04a 386 PANTHER PTHR11409 10 358 1.5E-99 T 23-04-2016 DC74_RS24965 c73497d4aae632b3fb93b26634dbf04a 386 SUPERFAMILY SSF51556 13 351 6.81E-72 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS39380 c4f616ff336911b2e23b5820339bd851 462 PANTHER PTHR24095:SF123 11 455 5.3E-136 T 23-04-2016 DC74_RS39380 c4f616ff336911b2e23b5820339bd851 462 Gene3D G3DSA:3.40.50.980 190 213 1.2E-23 T 23-04-2016 DC74_RS39380 c4f616ff336911b2e23b5820339bd851 462 Gene3D G3DSA:3.40.50.980 28 141 1.2E-23 T 23-04-2016 DC74_RS39380 c4f616ff336911b2e23b5820339bd851 462 Gene3D G3DSA:2.30.38.10 372 446 5.9E-20 T 23-04-2016 DC74_RS39380 c4f616ff336911b2e23b5820339bd851 462 SUPERFAMILY SSF56801 11 456 1.7E-86 T 23-04-2016 DC74_RS39380 c4f616ff336911b2e23b5820339bd851 462 PANTHER PTHR24095 11 455 5.3E-136 T 23-04-2016 DC74_RS39380 c4f616ff336911b2e23b5820339bd851 462 Gene3D G3DSA:3.40.50.980 214 351 1.5E-27 T 23-04-2016 DC74_RS39380 c4f616ff336911b2e23b5820339bd851 462 Pfam PF00501 AMP-binding enzyme 40 449 1.6E-66 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS03645 9a30d69c26cf47e52c234e617b2562a9 544 PANTHER PTHR19211:SF6 292 538 5.6E-231 T 23-04-2016 DC74_RS03645 9a30d69c26cf47e52c234e617b2562a9 544 PANTHER PTHR19211:SF6 1 252 5.6E-231 T 23-04-2016 DC74_RS03645 9a30d69c26cf47e52c234e617b2562a9 544 PANTHER PTHR19211 292 538 5.6E-231 T 23-04-2016 DC74_RS03645 9a30d69c26cf47e52c234e617b2562a9 544 PANTHER PTHR19211 1 252 5.6E-231 T 23-04-2016 DC74_RS03645 9a30d69c26cf47e52c234e617b2562a9 544 SUPERFAMILY SSF52540 7 222 3.7E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS03645 9a30d69c26cf47e52c234e617b2562a9 544 Gene3D G3DSA:3.40.50.300 8 262 8.3E-48 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS03645 9a30d69c26cf47e52c234e617b2562a9 544 Gene3D G3DSA:3.40.50.300 348 543 5.2E-36 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS03645 9a30d69c26cf47e52c234e617b2562a9 544 Pfam PF00005 ABC transporter 25 171 5.6E-20 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS03645 9a30d69c26cf47e52c234e617b2562a9 544 Pfam PF00005 ABC transporter 360 489 8.6E-19 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS03645 9a30d69c26cf47e52c234e617b2562a9 544 SMART SM00382 30 215 9.9E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS03645 9a30d69c26cf47e52c234e617b2562a9 544 SMART SM00382 367 539 2.3E-8 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS03645 9a30d69c26cf47e52c234e617b2562a9 544 SUPERFAMILY SSF52540 357 542 5.13E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25510 5304f628bb340c6d8e91a69ae4a87bba 319 PANTHER PTHR30419 10 315 9.6E-98 T 23-04-2016 DC74_RS25510 5304f628bb340c6d8e91a69ae4a87bba 319 SUPERFAMILY SSF53850 102 314 9.64E-39 T 23-04-2016 DC74_RS25510 5304f628bb340c6d8e91a69ae4a87bba 319 Gene3D G3DSA:1.10.10.10 14 93 6.5E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25510 5304f628bb340c6d8e91a69ae4a87bba 319 PANTHER PTHR30419:SF4 10 315 9.6E-98 T 23-04-2016 DC74_RS25510 5304f628bb340c6d8e91a69ae4a87bba 319 Pfam PF03466 LysR substrate binding domain 101 309 4.7E-44 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS25510 5304f628bb340c6d8e91a69ae4a87bba 319 SUPERFAMILY SSF46785 14 123 1.13E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25510 5304f628bb340c6d8e91a69ae4a87bba 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 75 2.0E-19 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS25510 5304f628bb340c6d8e91a69ae4a87bba 319 Gene3D G3DSA:3.40.190.10 103 188 9.6E-19 T 23-04-2016 DC74_RS25510 5304f628bb340c6d8e91a69ae4a87bba 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 5.3E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS25510 5304f628bb340c6d8e91a69ae4a87bba 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 5.3E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS25510 5304f628bb340c6d8e91a69ae4a87bba 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 5.3E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS25510 5304f628bb340c6d8e91a69ae4a87bba 319 Gene3D G3DSA:3.40.190.10 189 283 3.5E-25 T 23-04-2016 DC74_RS35375 3fe80f41a3a6f47e39e9dc0e73c33885 318 PANTHER PTHR30126 3 310 1.2E-81 T 23-04-2016 DC74_RS35375 3fe80f41a3a6f47e39e9dc0e73c33885 318 SUPERFAMILY SSF46785 3 113 5.45E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35375 3fe80f41a3a6f47e39e9dc0e73c33885 318 SUPERFAMILY SSF53850 91 296 6.52E-44 T 23-04-2016 DC74_RS35375 3fe80f41a3a6f47e39e9dc0e73c33885 318 Gene3D G3DSA:3.40.190.10 179 266 1.3E-18 T 23-04-2016 DC74_RS35375 3fe80f41a3a6f47e39e9dc0e73c33885 318 Pfam PF03466 LysR substrate binding domain 90 296 1.3E-45 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS35375 3fe80f41a3a6f47e39e9dc0e73c33885 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.1E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS35375 3fe80f41a3a6f47e39e9dc0e73c33885 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.1E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS35375 3fe80f41a3a6f47e39e9dc0e73c33885 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.1E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS35375 3fe80f41a3a6f47e39e9dc0e73c33885 318 Gene3D G3DSA:3.40.190.10 90 178 2.2E-20 T 23-04-2016 DC74_RS35375 3fe80f41a3a6f47e39e9dc0e73c33885 318 Gene3D G3DSA:1.10.10.10 3 88 2.1E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35375 3fe80f41a3a6f47e39e9dc0e73c33885 318 PANTHER PTHR30126:SF11 3 310 1.2E-81 T 23-04-2016 DC74_RS35375 3fe80f41a3a6f47e39e9dc0e73c33885 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 8.0E-20 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS02580 ca25eb8c178bd66ee53295c1edd83b1c 204 PANTHER PTHR11002 1 190 4.0E-58 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS02580 ca25eb8c178bd66ee53295c1edd83b1c 204 Gene3D G3DSA:3.40.1050.10 3 194 2.7E-66 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS02580 ca25eb8c178bd66ee53295c1edd83b1c 204 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 83 103 - T 23-04-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS02580 ca25eb8c178bd66ee53295c1edd83b1c 204 SUPERFAMILY SSF53056 3 192 8.37E-57 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS02580 ca25eb8c178bd66ee53295c1edd83b1c 204 Pfam PF00484 Carbonic anhydrase 34 186 1.1E-47 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS02580 ca25eb8c178bd66ee53295c1edd83b1c 204 SMART SM00947 27 191 6.7E-57 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS02580 ca25eb8c178bd66ee53295c1edd83b1c 204 PANTHER PTHR11002:SF13 1 190 4.0E-58 T 23-04-2016 DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 SUPERFAMILY SSF55874 311 474 1.96E-41 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 SMART SM00388 255 322 6.1E-22 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 Gene3D G3DSA:1.10.287.130 246 307 7.8E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 474 8.0E-23 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 SUPERFAMILY SSF47384 243 323 2.35E-18 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 SMART SM00304 187 247 1.5E-6 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 SMART SM00387 365 476 1.3E-37 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 Gene3D G3DSA:3.30.565.10 308 475 1.6E-44 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 7.9E-10 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 7.9E-10 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 Pfam PF00512 His Kinase A (phospho-acceptor) domain 256 322 3.0E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 Pfam PF00672 HAMP domain 169 241 3.6E-12 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS05920 867be4b47ab4f76ac7b96135dcf0bfcc 482 PANTHER PTHR24423 181 475 5.0E-77 T 23-04-2016 DC74_RS20180 41b8846d711710b37228f4fe441cdc08 255 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 23-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 DC74_RS20180 41b8846d711710b37228f4fe441cdc08 255 SUPERFAMILY SSF53790 2 233 1.96E-62 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS20180 41b8846d711710b37228f4fe441cdc08 255 PANTHER PTHR21091 1 208 3.6E-56 T 23-04-2016 DC74_RS20180 41b8846d711710b37228f4fe441cdc08 255 Gene3D G3DSA:3.40.1010.10 2 110 6.6E-35 T 23-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 DC74_RS20180 41b8846d711710b37228f4fe441cdc08 255 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 243 1.5E-88 T 23-04-2016 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 DC74_RS20180 41b8846d711710b37228f4fe441cdc08 255 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 23-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 DC74_RS20180 41b8846d711710b37228f4fe441cdc08 255 Gene3D G3DSA:3.30.950.10 111 232 2.1E-33 T 23-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 DC74_RS20180 41b8846d711710b37228f4fe441cdc08 255 PANTHER PTHR21091:SF17 1 208 3.6E-56 T 23-04-2016 DC74_RS20180 41b8846d711710b37228f4fe441cdc08 255 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 208 9.3E-40 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS17980 ba39e5cf43ca8255dffbb0425d67a4aa 314 Pfam PF00294 pfkB family carbohydrate kinase 24 289 1.8E-37 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS17980 ba39e5cf43ca8255dffbb0425d67a4aa 314 Gene3D G3DSA:3.40.1190.20 32 294 5.3E-71 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS17980 ba39e5cf43ca8255dffbb0425d67a4aa 314 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 294 1.6E-96 T 23-04-2016 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 DC74_RS17980 ba39e5cf43ca8255dffbb0425d67a4aa 314 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 294 5.0E-97 T 23-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 DC74_RS17980 ba39e5cf43ca8255dffbb0425d67a4aa 314 PIRSF PIRSF000535 1 294 3.9E-72 T 23-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 DC74_RS17980 ba39e5cf43ca8255dffbb0425d67a4aa 314 PANTHER PTHR10584 2 293 1.2E-85 T 23-04-2016 DC74_RS17980 ba39e5cf43ca8255dffbb0425d67a4aa 314 SUPERFAMILY SSF53613 3 290 1.06E-60 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS17980 ba39e5cf43ca8255dffbb0425d67a4aa 314 PANTHER PTHR10584:SF170 2 293 1.2E-85 T 23-04-2016 DC74_RS13190 921d95e485b286cffae7f3896426225d 215 Pfam PF00072 Response regulator receiver domain 3 120 2.3E-12 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS13190 921d95e485b286cffae7f3896426225d 215 Gene3D G3DSA:1.10.10.10 149 214 3.5E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13190 921d95e485b286cffae7f3896426225d 215 Gene3D G3DSA:3.40.50.2300 2 148 9.6E-25 T 23-04-2016 DC74_RS13190 921d95e485b286cffae7f3896426225d 215 PANTHER PTHR26402 1 209 1.3E-101 T 23-04-2016 DC74_RS13190 921d95e485b286cffae7f3896426225d 215 SMART SM00421 148 210 3.0E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13190 921d95e485b286cffae7f3896426225d 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 194 1.4E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13190 921d95e485b286cffae7f3896426225d 215 PANTHER PTHR26402:SF582 1 209 1.3E-101 T 23-04-2016 DC74_RS13190 921d95e485b286cffae7f3896426225d 215 SUPERFAMILY SSF52172 2 167 2.3E-19 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS13190 921d95e485b286cffae7f3896426225d 215 SMART SM00448 1 120 2.3E-9 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS13190 921d95e485b286cffae7f3896426225d 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 5.6E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13190 921d95e485b286cffae7f3896426225d 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 5.6E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13190 921d95e485b286cffae7f3896426225d 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 5.6E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 PANTHER PTHR11712 679 1577 4.9E-264 T 23-04-2016 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Gene3D G3DSA:3.40.50.980 25 189 1.3E-38 T 23-04-2016 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Gene3D G3DSA:3.40.47.10 946 1111 2.5E-50 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1061 1150 1.4E-9 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Gene3D G3DSA:3.40.366.10 1414 1527 2.2E-74 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Gene3D G3DSA:3.40.366.10 1218 1349 2.2E-74 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SUPERFAMILY SSF51735 1836 2079 2.85E-29 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Pfam PF08659 KR domain 1839 2040 1.3E-34 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Gene3D G3DSA:3.30.70.250 1353 1407 5.9E-5 T 23-04-2016 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1225 1525 6.1E-100 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Pfam PF00550 Phosphopantetheine attachment site 547 610 1.5E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Pfam PF00550 Phosphopantetheine attachment site 2130 2193 1.3E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Gene3D G3DSA:3.40.50.720 1837 2078 6.6E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 PANTHER PTHR11712:SF288 679 1577 4.9E-264 T 23-04-2016 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Gene3D G3DSA:3.40.50.980 190 339 1.4E-26 T 23-04-2016 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Gene3D G3DSA:3.30.300.30 422 523 8.9E-31 T 23-04-2016 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 846 862 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1839 2042 3.0E-22 T 23-04-2016 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Gene3D G3DSA:2.30.38.10 356 420 5.8E-8 T 23-04-2016 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SUPERFAMILY SSF56801 23 556 4.06E-118 T 23-04-2016 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SUPERFAMILY SSF55048 1353 1409 5.75E-8 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Pfam PF00698 Acyl transferase domain 1225 1521 4.1E-49 T 23-04-2016 IPR014043 Acyl transferase DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 942 1057 6.0E-36 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SUPERFAMILY SSF52151 1416 1510 1.99E-66 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SUPERFAMILY SSF52151 1222 1355 1.99E-66 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Gene3D G3DSA:3.40.47.10 680 945 1.4E-72 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SUPERFAMILY SSF53901 675 794 1.71E-77 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SUPERFAMILY SSF53901 1086 1105 1.71E-77 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SUPERFAMILY SSF53901 829 1053 1.71E-77 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SMART SM00825 Beta-ketoacyl synthase 680 1111 9.6E-144 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SUPERFAMILY SSF51735 1598 1824 1.73E-14 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Gene3D G3DSA:1.10.1200.10 539 615 1.0E-17 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Gene3D G3DSA:1.10.1200.10 2124 2198 1.0E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SUPERFAMILY SSF47336 2124 2207 1.83E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Pfam PF00501 AMP-binding enzyme 31 427 6.8E-69 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Pfam PF13193 AMP-binding enzyme C-terminal domain 436 511 6.8E-10 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2152 2167 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 679 933 3.6E-70 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SMART SM00823 Phosphopantetheine attachment site 2128 2197 1.1E-6 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SMART SM00823 Phosphopantetheine attachment site 545 614 0.014 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS01915 37389d16db6a4ad70dda71c0de87141d 2244 SUPERFAMILY SSF47336 541 610 5.63E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 SUPERFAMILY SSF52540 519 757 7.23E-74 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 Pfam PF03412 Peptidase C39 family 48 180 1.2E-36 T 23-04-2016 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 Pfam PF00005 ABC transporter 542 691 6.4E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 Gene3D G3DSA:3.90.70.10 55 179 4.2E-18 T 23-04-2016 DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 Gene3D G3DSA:3.40.50.300 523 753 1.4E-69 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 SUPERFAMILY SSF90123 199 511 1.31E-45 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 TIGRFAM TIGR03796 NHLM_micro_ABC1: NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein 47 757 0.0 T 23-04-2016 IPR022514 NHPM bacteriocin system ABC transporter, peptidase/ATP-binding protein DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 PANTHER PTHR24221 8 758 2.5E-240 T 23-04-2016 DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 Gene3D G3DSA:1.20.1560.10 199 499 5.1E-46 T 23-04-2016 DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 ProSitePatterns PS00211 ABC transporters family signature. 663 677 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 PANTHER PTHR24221:SF161 8 758 2.5E-240 T 23-04-2016 DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 SMART SM00382 550 741 2.3E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS07150 de1765aa41686678bb697dfe18486f9e 759 Pfam PF00664 ABC transporter transmembrane region 207 475 1.5E-21 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS28845 f624641f90c8a4b86f96491d2ba127ff 204 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 186 4.7E-27 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS28845 f624641f90c8a4b86f96491d2ba127ff 204 Gene3D G3DSA:1.20.120.450 2 50 7.4E-9 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS28845 f624641f90c8a4b86f96491d2ba127ff 204 SUPERFAMILY SSF109854 2 125 1.76E-17 T 23-04-2016 DC74_RS28845 f624641f90c8a4b86f96491d2ba127ff 204 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 8 93 8.9E-13 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS24780 523fc6ef255ea4760accbd2cf3979e38 257 Pfam PF13183 4Fe-4S dicluster domain 167 239 1.1E-11 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS24780 523fc6ef255ea4760accbd2cf3979e38 257 SUPERFAMILY SSF46548 128 253 1.71E-32 T 23-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 DC74_RS24780 523fc6ef255ea4760accbd2cf3979e38 257 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 169 180 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS24780 523fc6ef255ea4760accbd2cf3979e38 257 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 30 249 1.0E-79 T 23-04-2016 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 DC74_RS24780 523fc6ef255ea4760accbd2cf3979e38 257 Gene3D G3DSA:3.10.20.30 22 127 3.8E-39 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS24780 523fc6ef255ea4760accbd2cf3979e38 257 Gene3D G3DSA:1.10.1060.10 128 255 1.7E-39 T 23-04-2016 DC74_RS24780 523fc6ef255ea4760accbd2cf3979e38 257 PANTHER PTHR11921:SF15 7 257 5.0E-115 T 23-04-2016 DC74_RS24780 523fc6ef255ea4760accbd2cf3979e38 257 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 27 132 2.1E-35 T 23-04-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 DC74_RS24780 523fc6ef255ea4760accbd2cf3979e38 257 SUPERFAMILY SSF54292 24 127 5.82E-29 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS24780 523fc6ef255ea4760accbd2cf3979e38 257 PANTHER PTHR11921 7 257 5.0E-115 T 23-04-2016 DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 SUPERFAMILY SSF55874 466 557 2.23E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 SMART SM00387 461 558 2.7E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 Pfam PF07730 Histidine kinase 357 418 2.0E-11 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 Gene3D G3DSA:3.30.450.40 26 182 6.4E-33 T 23-04-2016 IPR029016 GAF domain-like DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 SMART SM00065 37 185 4.1E-23 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 SMART SM00065 206 349 2.4E-17 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 SUPERFAMILY SSF55781 206 352 5.45E-23 T 23-04-2016 IPR029016 GAF domain-like DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 PANTHER PTHR11347 24 350 9.6E-42 T 23-04-2016 DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 PANTHER PTHR11347 428 436 9.6E-42 T 23-04-2016 DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 SUPERFAMILY SSF55781 23 193 2.4E-34 T 23-04-2016 IPR029016 GAF domain-like DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 PANTHER PTHR11347:SF114 24 350 9.6E-42 T 23-04-2016 IPR027035 Hypoxia/Redox sensor histidine kinase response regulator DosT/DevS GO:0004673|GO:0046777|GO:0070483 DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 PANTHER PTHR11347:SF114 428 436 9.6E-42 T 23-04-2016 IPR027035 Hypoxia/Redox sensor histidine kinase response regulator DosT/DevS GO:0004673|GO:0046777|GO:0070483 DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 Pfam PF13185 GAF domain 36 175 2.8E-23 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 Pfam PF13185 GAF domain 205 339 3.6E-19 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 Gene3D G3DSA:3.30.565.10 464 515 1.1E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21025 21970a595d32f2d8cb8b089af1a8072d 558 Gene3D G3DSA:3.30.450.40 185 352 2.1E-22 T 23-04-2016 IPR029016 GAF domain-like DC74_RS33250 3cfe0d3978510c2fb9558fd083019de2 269 SUPERFAMILY SSF52799 15 267 8.99E-51 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS33250 3cfe0d3978510c2fb9558fd083019de2 269 PANTHER PTHR31126:SF21 126 201 6.6E-71 T 23-04-2016 DC74_RS33250 3cfe0d3978510c2fb9558fd083019de2 269 PANTHER PTHR31126 219 269 6.6E-71 T 23-04-2016 DC74_RS33250 3cfe0d3978510c2fb9558fd083019de2 269 PANTHER PTHR31126 1 93 6.6E-71 T 23-04-2016 DC74_RS33250 3cfe0d3978510c2fb9558fd083019de2 269 PANTHER PTHR31126:SF21 219 269 6.6E-71 T 23-04-2016 DC74_RS33250 3cfe0d3978510c2fb9558fd083019de2 269 PANTHER PTHR31126:SF21 1 93 6.6E-71 T 23-04-2016 DC74_RS33250 3cfe0d3978510c2fb9558fd083019de2 269 Gene3D G3DSA:3.90.190.10 135 194 1.4E-17 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS33250 3cfe0d3978510c2fb9558fd083019de2 269 Gene3D G3DSA:3.90.190.10 17 100 1.4E-17 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS33250 3cfe0d3978510c2fb9558fd083019de2 269 Pfam PF13350 Tyrosine phosphatase family 14 267 1.5E-62 T 23-04-2016 IPR026893 Tyrosine/serine-protein phosphatase IphP-type DC74_RS33250 3cfe0d3978510c2fb9558fd083019de2 269 PANTHER PTHR31126 126 201 6.6E-71 T 23-04-2016 DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 PANTHER PTHR22855 53 435 9.1E-162 T 23-04-2016 DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 PANTHER PTHR22855 16 34 9.1E-162 T 23-04-2016 DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 Gene3D G3DSA:3.90.226.10 14 242 1.4E-36 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 Pfam PF01039 Carboxyl transferase domain 62 218 6.5E-15 T 23-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 Pfam PF01039 Carboxyl transferase domain 321 436 8.2E-11 T 23-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 SUPERFAMILY SSF52096 262 466 3.45E-50 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 Gene3D G3DSA:3.90.226.10 266 467 5.7E-34 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 PANTHER PTHR22855:SF42 53 435 9.1E-162 T 23-04-2016 DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 PANTHER PTHR22855:SF42 16 34 9.1E-162 T 23-04-2016 DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 SUPERFAMILY SSF52096 14 241 3.37E-42 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 193 204 1.5E-13 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 93 107 1.5E-13 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 127 145 1.5E-13 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 DC74_RS07965 d2a2c33219b6382f00ce4dc4ab9aac34 472 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 164 181 1.5E-13 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 Pfam PF12344 Ultra-violet resistance protein B 559 600 9.9E-22 T 23-04-2016 IPR024759 UvrB, YAD/RRR-motif-containing domain DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 SUPERFAMILY SSF52540 42 91 2.32E-34 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 SUPERFAMILY SSF52540 466 588 2.32E-34 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 Pfam PF02151 UvrB/uvrC motif 673 705 1.3E-6 T 23-04-2016 IPR001943 UVR domain GO:0005515 DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 PANTHER PTHR24029 8 611 0.0 T 23-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 PANTHER PTHR24029 644 709 0.0 T 23-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 SUPERFAMILY SSF46600 665 708 1.28E-9 T 23-04-2016 IPR001943 UVR domain GO:0005515 DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 Hamap MF_00204 UvrABC system protein B [uvrB]. 12 705 42.468 T 23-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 SMART SM00487 18 433 7.1E-26 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 Pfam PF04851 Type III restriction enzyme, res subunit 22 134 4.7E-8 T 23-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 Gene3D G3DSA:3.40.50.300 396 417 3.3E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 Gene3D G3DSA:3.40.50.300 15 98 3.3E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 Gene3D G3DSA:3.40.50.300 286 346 3.3E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 Gene3D G3DSA:3.40.50.300 426 588 3.7E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 14 703 0.0 T 23-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 Gene3D G3DSA:3.30.2060.10 170 237 5.1E-11 T 23-04-2016 DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 Pfam PF00271 Helicase conserved C-terminal domain 439 552 1.1E-19 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 Gene3D G3DSA:4.10.860.10 661 709 9.3E-14 T 23-04-2016 IPR001943 UVR domain GO:0005515 DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 SMART SM00490 467 553 2.8E-18 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS11935 1463ea2140eb79481aee54e3ec9fa8dd 715 SUPERFAMILY SSF52540 13 422 2.28E-134 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23700 84bfcdd6e27247948efb2749b3d5db61 283 Gene3D G3DSA:3.40.190.10 79 182 3.1E-14 T 23-04-2016 DC74_RS23700 84bfcdd6e27247948efb2749b3d5db61 283 SUPERFAMILY SSF53850 5 272 1.36E-81 T 23-04-2016 DC74_RS23700 84bfcdd6e27247948efb2749b3d5db61 283 Pfam PF02621 Menaquinone biosynthesis 5 267 1.0E-87 T 23-04-2016 IPR003773 Menaquinone biosynthesis enzyme UniPathway: UPA00079 DC74_RS23700 84bfcdd6e27247948efb2749b3d5db61 283 PANTHER PTHR37167 3 283 3.8E-104 T 23-04-2016 DC74_RS23700 84bfcdd6e27247948efb2749b3d5db61 283 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 4 273 40.604 T 23-04-2016 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 UniPathway: UPA00079 DC74_RS36155 37754f3a24aee11318bd8963b962ef67 165 SUPERFAMILY SSF109854 3 157 3.36E-32 T 23-04-2016 DC74_RS36155 37754f3a24aee11318bd8963b962ef67 165 Pfam PF04978 Protein of unknown function (DUF664) 8 158 9.8E-34 T 23-04-2016 IPR007061 Protein of unknown function DUF664 DC74_RS36155 37754f3a24aee11318bd8963b962ef67 165 Gene3D G3DSA:1.20.120.450 3 159 9.1E-31 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS14940 106cbdb533d629cfea9389004d570c39 456 TIGRFAM TIGR03356 BGL: beta-galactosidase 18 448 1.4E-164 T 23-04-2016 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 DC74_RS14940 106cbdb533d629cfea9389004d570c39 456 PANTHER PTHR10353 17 455 4.5E-185 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DC74_RS14940 106cbdb533d629cfea9389004d570c39 456 SUPERFAMILY SSF51445 17 455 4.16E-153 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS14940 106cbdb533d629cfea9389004d570c39 456 PANTHER PTHR10353:SF36 17 455 4.5E-185 T 23-04-2016 DC74_RS14940 106cbdb533d629cfea9389004d570c39 456 Pfam PF00232 Glycosyl hydrolase family 1 17 455 8.4E-137 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DC74_RS14940 106cbdb533d629cfea9389004d570c39 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 293 307 6.0E-20 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DC74_RS14940 106cbdb533d629cfea9389004d570c39 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 403 420 6.0E-20 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DC74_RS14940 106cbdb533d629cfea9389004d570c39 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 382 393 6.0E-20 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DC74_RS14940 106cbdb533d629cfea9389004d570c39 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 427 439 6.0E-20 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DC74_RS14940 106cbdb533d629cfea9389004d570c39 456 PRINTS PR00131 Glycosyl hydrolase family 1 signature 368 376 6.0E-20 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DC74_RS14940 106cbdb533d629cfea9389004d570c39 456 Gene3D G3DSA:3.20.20.80 17 455 2.6E-149 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS02675 bc1344825bf70fe15fbdcc21911dac84 294 PANTHER PTHR13600:SF20 76 211 9.5E-65 T 23-04-2016 DC74_RS02675 bc1344825bf70fe15fbdcc21911dac84 294 PANTHER PTHR13600:SF20 2 55 9.5E-65 T 23-04-2016 DC74_RS02675 bc1344825bf70fe15fbdcc21911dac84 294 SUPERFAMILY SSF53335 13 280 6.41E-65 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS02675 bc1344825bf70fe15fbdcc21911dac84 294 Pfam PF04072 Leucine carboxyl methyltransferase 17 198 8.0E-53 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS02675 bc1344825bf70fe15fbdcc21911dac84 294 PANTHER PTHR13600 76 211 9.5E-65 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS02675 bc1344825bf70fe15fbdcc21911dac84 294 PANTHER PTHR13600 2 55 9.5E-65 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS02675 bc1344825bf70fe15fbdcc21911dac84 294 Gene3D G3DSA:3.40.50.150 20 206 1.4E-9 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS02675 bc1344825bf70fe15fbdcc21911dac84 294 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 15 274 1.4E-76 T 23-04-2016 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 Gene3D G3DSA:3.40.50.80 262 403 2.3E-28 T 23-04-2016 DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 Pfam PF00175 Oxidoreductase NAD-binding domain 272 381 1.1E-8 T 23-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 Pfam PF00042 Globin 10 105 2.1E-9 T 23-04-2016 IPR000971 Globin GO:0019825|GO:0020037 DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 Gene3D G3DSA:1.10.490.10 2 146 2.6E-44 T 23-04-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 PRINTS PR00410 Phenol hydroxylase reductase family signature 269 288 2.5E-5 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 PRINTS PR00410 Phenol hydroxylase reductase family signature 186 198 2.5E-5 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 PRINTS PR00410 Phenol hydroxylase reductase family signature 368 376 2.5E-5 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 SUPERFAMILY SSF63380 154 261 9.44E-30 T 23-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 Gene3D G3DSA:2.40.30.10 154 261 7.2E-35 T 23-04-2016 DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 SUPERFAMILY SSF52343 262 402 1.26E-30 T 23-04-2016 DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 SUPERFAMILY SSF46458 2 144 1.83E-32 T 23-04-2016 IPR009050 Globin-like DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 Pfam PF00970 Oxidoreductase FAD-binding domain 158 259 8.3E-10 T 23-04-2016 IPR008333 Oxidoreductase, FAD-binding domain DC74_RS03830 0d022dc9e232891863ad355bc01b6c6d 409 PANTHER PTHR22924 2 406 5.8E-96 T 23-04-2016 DC74_RS21350 f14e0d6387d475c8d11d8163e1d4ed2c 402 PANTHER PTHR10909 6 402 1.2E-102 T 23-04-2016 DC74_RS21350 f14e0d6387d475c8d11d8163e1d4ed2c 402 SUPERFAMILY SSF56645 5 250 6.68E-57 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS21350 f14e0d6387d475c8d11d8163e1d4ed2c 402 SUPERFAMILY SSF47203 236 399 7.41E-22 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS21350 f14e0d6387d475c8d11d8163e1d4ed2c 402 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 116 220 4.5E-19 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS21350 f14e0d6387d475c8d11d8163e1d4ed2c 402 Gene3D G3DSA:1.10.540.10 6 113 8.9E-20 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS21350 f14e0d6387d475c8d11d8163e1d4ed2c 402 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 390 3.7E-29 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS21350 f14e0d6387d475c8d11d8163e1d4ed2c 402 Gene3D G3DSA:2.40.110.10 115 226 1.3E-32 T 23-04-2016 DC74_RS21350 f14e0d6387d475c8d11d8163e1d4ed2c 402 PANTHER PTHR10909:SF229 6 402 1.2E-102 T 23-04-2016 DC74_RS21350 f14e0d6387d475c8d11d8163e1d4ed2c 402 Gene3D G3DSA:1.20.140.10 227 399 1.5E-33 T 23-04-2016 DC74_RS21350 f14e0d6387d475c8d11d8163e1d4ed2c 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 112 8.7E-19 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS12885 1b4339a13aa6b8cf2bb561a510231926 545 SUPERFAMILY SSF81342 23 300 8.16E-63 T 23-04-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 DC74_RS12885 1b4339a13aa6b8cf2bb561a510231926 545 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 124 297 3.4E-58 T 23-04-2016 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 DC74_RS12885 1b4339a13aa6b8cf2bb561a510231926 545 PANTHER PTHR19271:SF7 96 473 5.6E-224 T 23-04-2016 DC74_RS12885 1b4339a13aa6b8cf2bb561a510231926 545 PANTHER PTHR19271:SF7 19 78 5.6E-224 T 23-04-2016 DC74_RS12885 1b4339a13aa6b8cf2bb561a510231926 545 Gene3D G3DSA:1.20.810.10 23 444 6.6E-92 T 23-04-2016 IPR027387 Cytochrome b/b6-like domain DC74_RS12885 1b4339a13aa6b8cf2bb561a510231926 545 PANTHER PTHR19271 96 473 5.6E-224 T 23-04-2016 DC74_RS12885 1b4339a13aa6b8cf2bb561a510231926 545 PANTHER PTHR19271 19 78 5.6E-224 T 23-04-2016 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 38 642 4.8E-193 T 23-04-2016 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969|UniPathway: UPA00223 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 549 615 3.4E-6 T 23-04-2016 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 Gene3D G3DSA:3.40.50.920 548 647 2.7E-9 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 Gene3D G3DSA:3.40.920.10 38 237 2.7E-23 T 23-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 SUPERFAMILY SSF52518 260 528 1.91E-58 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 PANTHER PTHR32154 281 447 1.8E-258 T 23-04-2016 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 PANTHER PTHR32154 30 258 1.8E-258 T 23-04-2016 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 PANTHER PTHR32154 483 648 1.8E-258 T 23-04-2016 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 PANTHER PTHR32154:SF14 483 648 1.8E-258 T 23-04-2016 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 PANTHER PTHR32154:SF14 281 447 1.8E-258 T 23-04-2016 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 PANTHER PTHR32154:SF14 30 258 1.8E-258 T 23-04-2016 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 46 234 5.1E-25 T 23-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 289 503 7.6E-51 T 23-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 SUPERFAMILY SSF53323 40 260 9.02E-17 T 23-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 SUPERFAMILY SSF52922 548 649 1.83E-12 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS18965 43c3b32b57eb0a3fb7d25761471ce34c 650 Gene3D G3DSA:3.40.50.970 258 452 1.0E-71 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS37430 cc35ac0c6dafbba130f7b9fa9493360a 661 Gene3D G3DSA:3.40.710.10 265 631 1.9E-69 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS37430 cc35ac0c6dafbba130f7b9fa9493360a 661 Pfam PF00912 Transglycosylase 87 263 5.0E-58 T 23-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 DC74_RS37430 cc35ac0c6dafbba130f7b9fa9493360a 661 SUPERFAMILY SSF56601 247 267 1.87E-56 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS37430 cc35ac0c6dafbba130f7b9fa9493360a 661 SUPERFAMILY SSF56601 297 627 1.87E-56 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS37430 cc35ac0c6dafbba130f7b9fa9493360a 661 PANTHER PTHR32282:SF8 16 627 7.5E-156 T 23-04-2016 DC74_RS37430 cc35ac0c6dafbba130f7b9fa9493360a 661 SUPERFAMILY SSF53955 75 286 1.04E-64 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS37430 cc35ac0c6dafbba130f7b9fa9493360a 661 Gene3D G3DSA:1.10.3810.10 88 264 6.9E-62 T 23-04-2016 DC74_RS37430 cc35ac0c6dafbba130f7b9fa9493360a 661 PANTHER PTHR32282 16 627 7.5E-156 T 23-04-2016 DC74_RS37430 cc35ac0c6dafbba130f7b9fa9493360a 661 Pfam PF00905 Penicillin binding protein transpeptidase domain 442 624 9.1E-15 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS35770 d1ddddbd7f660fea87c75bfc5b75fc5b 590 Gene3D G3DSA:3.40.50.970 1 179 1.4E-58 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS35770 d1ddddbd7f660fea87c75bfc5b75fc5b 590 Gene3D G3DSA:3.40.50.1220 183 357 1.7E-48 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS35770 d1ddddbd7f660fea87c75bfc5b75fc5b 590 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 1 586 0.0 T 23-04-2016 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47|UniPathway: UPA00864 DC74_RS35770 d1ddddbd7f660fea87c75bfc5b75fc5b 590 PANTHER PTHR18968:SF14 1 574 0.0 T 23-04-2016 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47|UniPathway: UPA00864 DC74_RS35770 d1ddddbd7f660fea87c75bfc5b75fc5b 590 SUPERFAMILY SSF52518 1 181 3.47E-47 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS35770 d1ddddbd7f660fea87c75bfc5b75fc5b 590 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 324 2.0E-33 T 23-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DC74_RS35770 d1ddddbd7f660fea87c75bfc5b75fc5b 590 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 549 3.7E-34 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS35770 d1ddddbd7f660fea87c75bfc5b75fc5b 590 Gene3D G3DSA:3.40.50.970 358 564 6.9E-60 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS35770 d1ddddbd7f660fea87c75bfc5b75fc5b 590 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 169 2.1E-49 T 23-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DC74_RS35770 d1ddddbd7f660fea87c75bfc5b75fc5b 590 SUPERFAMILY SSF52467 158 337 4.36E-46 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS35770 d1ddddbd7f660fea87c75bfc5b75fc5b 590 PANTHER PTHR18968 1 574 0.0 T 23-04-2016 DC74_RS35770 d1ddddbd7f660fea87c75bfc5b75fc5b 590 SUPERFAMILY SSF52518 366 561 2.14E-51 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS18175 2e53118268214317493d89eed477c7bd 528 PANTHER PTHR11785 503 509 1.7E-24 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS18175 2e53118268214317493d89eed477c7bd 528 PANTHER PTHR11785 78 434 1.7E-24 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS18175 2e53118268214317493d89eed477c7bd 528 PIRSF PIRSF006060 18 513 6.8E-52 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS18175 2e53118268214317493d89eed477c7bd 528 Pfam PF13520 Amino acid permease 44 440 4.8E-28 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 PANTHER PTHR24322 11 142 1.0E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 PANTHER PTHR24322 159 193 1.0E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.3E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.3E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 8.3E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 Gene3D G3DSA:3.40.50.720 6 258 2.5E-57 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 SUPERFAMILY SSF51735 5 207 2.79E-54 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 SUPERFAMILY SSF51735 235 269 2.79E-54 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 Pfam PF00106 short chain dehydrogenase 7 193 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.4E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.4E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.4E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11395 3d7914930cbbeb7bac1633ddc94967d2 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.4E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18575 3ebd0cc0472f4d94cb566a61600996a7 170 SUPERFAMILY SSF54211 46 170 1.37E-41 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS18575 3ebd0cc0472f4d94cb566a61600996a7 170 Gene3D G3DSA:3.30.230.10 46 170 1.4E-46 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS18575 3ebd0cc0472f4d94cb566a61600996a7 170 Pfam PF00380 Ribosomal protein S9/S16 49 170 7.6E-43 T 23-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 DC74_RS18575 3ebd0cc0472f4d94cb566a61600996a7 170 PANTHER PTHR21569 43 170 1.9E-56 T 23-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 DC74_RS18575 3ebd0cc0472f4d94cb566a61600996a7 170 ProSitePatterns PS00360 Ribosomal protein S9 signature. 108 126 - T 23-04-2016 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 DC74_RS18575 3ebd0cc0472f4d94cb566a61600996a7 170 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 40 170 32.463 T 23-04-2016 IPR023035 Ribosomal protein S9, bacterial/plastid DC74_RS23725 7493ce53eb4af154e8ea134f31afd2c4 1076 SUPERFAMILY SSF55874 51 149 4.1E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23725 7493ce53eb4af154e8ea134f31afd2c4 1076 Gene3D G3DSA:3.30.565.10 29 240 7.8E-16 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23725 7493ce53eb4af154e8ea134f31afd2c4 1076 PANTHER PTHR32387:SF5 18 649 8.0E-249 T 23-04-2016 DC74_RS23725 7493ce53eb4af154e8ea134f31afd2c4 1076 PANTHER PTHR32387 18 649 8.0E-249 T 23-04-2016 DC74_RS17585 9fe4a4204c5d617cf32cb3ab3460586c 196 PANTHER PTHR35400 11 194 1.6E-28 T 23-04-2016 DC74_RS17585 9fe4a4204c5d617cf32cb3ab3460586c 196 SUPERFAMILY SSF52980 12 149 3.59E-17 T 23-04-2016 IPR011335 Restriction endonuclease type II-like DC74_RS17585 9fe4a4204c5d617cf32cb3ab3460586c 196 PANTHER PTHR35400:SF1 11 194 1.6E-28 T 23-04-2016 DC74_RS17585 9fe4a4204c5d617cf32cb3ab3460586c 196 Gene3D G3DSA:3.90.1570.10 14 148 2.0E-14 T 23-04-2016 IPR012296 Nuclease, putative, TT1808 DC74_RS17585 9fe4a4204c5d617cf32cb3ab3460586c 196 Pfam PF05685 Putative restriction endonuclease 23 183 9.7E-24 T 23-04-2016 IPR008538 Domain of unknown function DUF820 DC74_RS29815 a7f17557e249961ee5b8a044fdd2c405 485 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 14 474 1.2E-62 T 23-04-2016 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|UniPathway: UPA00251 DC74_RS29815 a7f17557e249961ee5b8a044fdd2c405 485 Pfam PF01593 Flavin containing amine oxidoreductase 22 474 2.1E-46 T 23-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 DC74_RS29815 a7f17557e249961ee5b8a044fdd2c405 485 Gene3D G3DSA:1.10.3110.10 115 208 3.4E-25 T 23-04-2016 DC74_RS29815 a7f17557e249961ee5b8a044fdd2c405 485 SUPERFAMILY SSF54373 314 424 1.33E-27 T 23-04-2016 DC74_RS29815 a7f17557e249961ee5b8a044fdd2c405 485 SUPERFAMILY SSF51905 14 330 4.4E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS29815 a7f17557e249961ee5b8a044fdd2c405 485 SUPERFAMILY SSF51905 441 475 4.4E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS29815 a7f17557e249961ee5b8a044fdd2c405 485 Gene3D G3DSA:3.90.660.20 251 424 3.4E-35 T 23-04-2016 IPR027418 Protoporphyrinogen oxidase, C-terminal domain KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|UniPathway: UPA00251 DC74_RS29815 a7f17557e249961ee5b8a044fdd2c405 485 PANTHER PTHR10742 12 477 3.9E-209 T 23-04-2016 DC74_RS29815 a7f17557e249961ee5b8a044fdd2c405 485 Gene3D G3DSA:3.40.50.720 12 54 8.8E-11 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29815 a7f17557e249961ee5b8a044fdd2c405 485 PANTHER PTHR10742:SF262 12 477 3.9E-209 T 23-04-2016 DC74_RS08580 402f615ca7458e7c047ef70ba24bc4db 458 TIGRFAM TIGR03173 pbuX: xanthine permease 29 439 6.6E-155 T 23-04-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 DC74_RS08580 402f615ca7458e7c047ef70ba24bc4db 458 PANTHER PTHR11119 14 440 2.9E-108 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS08580 402f615ca7458e7c047ef70ba24bc4db 458 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 21 436 1.6E-109 T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 DC74_RS08580 402f615ca7458e7c047ef70ba24bc4db 458 PANTHER PTHR11119:SF3 14 440 2.9E-108 T 23-04-2016 DC74_RS08580 402f615ca7458e7c047ef70ba24bc4db 458 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 354 374 - T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 DC74_RS08580 402f615ca7458e7c047ef70ba24bc4db 458 Pfam PF00860 Permease family 24 407 3.0E-96 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 148 495 5.0E-122 T 23-04-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 24 144 1.1E-18 T 23-04-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 PANTHER PTHR22600:SF21 225 545 4.1E-212 T 23-04-2016 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 PANTHER PTHR22600:SF21 80 208 4.1E-212 T 23-04-2016 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 SUPERFAMILY SSF51445 148 511 7.09E-120 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 PIRSF PIRSF001093 81 539 8.2E-74 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 Gene3D G3DSA:3.30.379.10 6 145 1.3E-23 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 SUPERFAMILY SSF55545 5 147 1.19E-17 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 PANTHER PTHR22600 80 208 4.1E-212 T 23-04-2016 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 PANTHER PTHR22600 225 545 4.1E-212 T 23-04-2016 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 293 311 3.4E-37 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 98 118 3.4E-37 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 477 494 3.4E-37 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 459 475 3.4E-37 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 171 192 3.4E-37 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 315 328 3.4E-37 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 PRINTS PR00738 Glycosyl hydrolase family 20 signature 242 259 3.4E-37 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS16575 54ce492335ac2e5bdeca7237d26abc38 552 Gene3D G3DSA:3.20.20.80 146 529 1.3E-137 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS05245 449c6399233483e158f24a89d2c939a8 266 PANTHER PTHR10108 5 148 3.8E-19 T 23-04-2016 DC74_RS05245 449c6399233483e158f24a89d2c939a8 266 PANTHER PTHR10108 193 228 3.8E-19 T 23-04-2016 DC74_RS05245 449c6399233483e158f24a89d2c939a8 266 Gene3D G3DSA:3.40.50.150 17 228 5.5E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS05245 449c6399233483e158f24a89d2c939a8 266 SUPERFAMILY SSF53335 21 241 4.71E-35 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS05245 449c6399233483e158f24a89d2c939a8 266 Pfam PF13649 Methyltransferase domain 42 134 1.5E-17 T 23-04-2016 DC74_RS16105 67821b8d0045ce1959c24716d549f2f9 246 SUPERFAMILY SSF161098 9 198 2.88E-39 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16105 67821b8d0045ce1959c24716d549f2f9 246 PANTHER PTHR30614:SF9 1 218 8.1E-96 T 23-04-2016 DC74_RS16105 67821b8d0045ce1959c24716d549f2f9 246 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 107 4.5E-23 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 DC74_RS16105 67821b8d0045ce1959c24716d549f2f9 246 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 10 216 2.3E-69 T 23-04-2016 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC DC74_RS16105 67821b8d0045ce1959c24716d549f2f9 246 Gene3D G3DSA:1.10.3720.10 10 212 8.8E-42 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16105 67821b8d0045ce1959c24716d549f2f9 246 PANTHER PTHR30614 1 218 8.1E-96 T 23-04-2016 DC74_RS16105 67821b8d0045ce1959c24716d549f2f9 246 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 211 2.6E-18 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 PANTHER PTHR12592 5 474 2.5E-100 T 23-04-2016 DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 PIRSF PIRSF017184 1 477 3.2E-100 T 23-04-2016 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 SUPERFAMILY SSF64153 4 234 4.32E-49 T 23-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 Gene3D G3DSA:3.40.1190.20 220 473 1.5E-79 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 217 468 6.1E-47 T 23-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 213 476 20.241 T 23-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 296 306 - T 23-04-2016 IPR017953 Carbohydrate kinase, predicted, conserved site DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 Pfam PF01256 Carbohydrate kinase 236 456 6.7E-50 T 23-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 Pfam PF03853 YjeF-related protein N-terminus 25 181 8.2E-40 T 23-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 Gene3D G3DSA:3.40.50.10260 3 219 1.4E-57 T 23-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 SUPERFAMILY SSF53613 214 472 4.62E-54 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 20 202 9.9E-29 T 23-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 PANTHER PTHR12592:SF0 5 474 2.5E-100 T 23-04-2016 DC74_RS18545 19d2ea516c714a5a20a2cffadfe0d36b 477 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 3 202 20.434 T 23-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 DC74_RS35985 26afe384b67714402b35abea8456adbf 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS35985 26afe384b67714402b35abea8456adbf 514 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 497 2.5E-13 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS35985 26afe384b67714402b35abea8456adbf 514 Pfam PF00501 AMP-binding enzyme 19 413 7.2E-86 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS35985 26afe384b67714402b35abea8456adbf 514 PANTHER PTHR24096 9 506 4.0E-136 T 23-04-2016 DC74_RS35985 26afe384b67714402b35abea8456adbf 514 PANTHER PTHR24096:SF232 9 506 4.0E-136 T 23-04-2016 DC74_RS35985 26afe384b67714402b35abea8456adbf 514 SUPERFAMILY SSF56801 9 509 3.79E-123 T 23-04-2016 DC74_RS35985 26afe384b67714402b35abea8456adbf 514 Gene3D G3DSA:3.30.300.30 408 507 2.7E-22 T 23-04-2016 DC74_RS35985 26afe384b67714402b35abea8456adbf 514 Gene3D G3DSA:2.30.38.10 332 404 3.6E-28 T 23-04-2016 DC74_RS35985 26afe384b67714402b35abea8456adbf 514 Gene3D G3DSA:3.40.50.980 173 323 8.5E-28 T 23-04-2016 DC74_RS35985 26afe384b67714402b35abea8456adbf 514 Gene3D G3DSA:3.40.50.980 18 172 3.2E-26 T 23-04-2016 DC74_RS34440 f3161b678bbb23d8126002385e9d93c1 441 Gene3D G3DSA:3.40.640.10 66 323 5.7E-74 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS34440 f3161b678bbb23d8126002385e9d93c1 441 PANTHER PTHR11986 29 441 4.5E-101 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS34440 f3161b678bbb23d8126002385e9d93c1 441 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS34440 f3161b678bbb23d8126002385e9d93c1 441 Pfam PF00202 Aminotransferase class-III 29 433 1.4E-86 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS34440 f3161b678bbb23d8126002385e9d93c1 441 SUPERFAMILY SSF53383 28 436 1.73E-100 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS34440 f3161b678bbb23d8126002385e9d93c1 441 Gene3D G3DSA:3.90.1150.10 324 436 8.7E-22 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS30680 11b2c31fd9018ab0e0f8ac1e0a0efb24 166 Pfam PF05713 Bacterial mobilisation protein (MobC) 115 155 3.3E-5 T 23-04-2016 IPR008687 Bacterial mobilisation DC74_RS32180 3124913102490a039e37599fc15b1314 99 SUPERFAMILY SSF46785 4 93 4.34E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32180 3124913102490a039e37599fc15b1314 99 Pfam PF13601 Winged helix DNA-binding domain 15 92 2.8E-19 T 23-04-2016 IPR027395 Winged helix DNA-binding domain DC74_RS32180 3124913102490a039e37599fc15b1314 99 Gene3D G3DSA:1.10.10.10 6 93 1.1E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32180 3124913102490a039e37599fc15b1314 99 PANTHER PTHR37318 1 97 1.3E-15 T 23-04-2016 DC74_RS00255 161dcb2effb36369d2d1ac5c9cc36ade 230 Pfam PF13649 Methyltransferase domain 52 145 2.7E-11 T 23-04-2016 DC74_RS00255 161dcb2effb36369d2d1ac5c9cc36ade 230 Gene3D G3DSA:3.40.50.150 42 210 1.1E-23 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS00255 161dcb2effb36369d2d1ac5c9cc36ade 230 PANTHER PTHR10108 40 209 5.0E-14 T 23-04-2016 DC74_RS00255 161dcb2effb36369d2d1ac5c9cc36ade 230 SUPERFAMILY SSF53335 41 211 3.41E-25 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS36315 9e46c3bdd28938c0fe4afac8301fe1a6 356 PANTHER PTHR10909 1 354 8.4E-88 T 23-04-2016 DC74_RS36315 9e46c3bdd28938c0fe4afac8301fe1a6 356 Gene3D G3DSA:1.10.540.10 9 98 2.6E-11 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS36315 9e46c3bdd28938c0fe4afac8301fe1a6 356 SUPERFAMILY SSF47203 200 346 5.48E-39 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS36315 9e46c3bdd28938c0fe4afac8301fe1a6 356 Gene3D G3DSA:1.20.140.10 187 340 1.1E-36 T 23-04-2016 DC74_RS36315 9e46c3bdd28938c0fe4afac8301fe1a6 356 Gene3D G3DSA:2.40.110.10 111 186 3.3E-10 T 23-04-2016 DC74_RS36315 9e46c3bdd28938c0fe4afac8301fe1a6 356 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 89 1.7E-9 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS36315 9e46c3bdd28938c0fe4afac8301fe1a6 356 PANTHER PTHR10909:SF302 1 354 8.4E-88 T 23-04-2016 DC74_RS36315 9e46c3bdd28938c0fe4afac8301fe1a6 356 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 200 345 1.5E-27 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS36315 9e46c3bdd28938c0fe4afac8301fe1a6 356 SUPERFAMILY SSF56645 3 197 8.77E-35 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS12475 18064264496f687194d16c5203e9dcf3 530 PANTHER PTHR10110 4 408 4.7E-95 T 23-04-2016 IPR018422 Cation/H+ exchanger, CPA1 family GO:0006812|GO:0015299|GO:0016021 Reactome: REACT_15518 DC74_RS12475 18064264496f687194d16c5203e9dcf3 530 PANTHER PTHR10110 425 501 4.7E-95 T 23-04-2016 IPR018422 Cation/H+ exchanger, CPA1 family GO:0006812|GO:0015299|GO:0016021 Reactome: REACT_15518 DC74_RS12475 18064264496f687194d16c5203e9dcf3 530 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 9 524 1.4E-95 T 23-04-2016 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 DC74_RS12475 18064264496f687194d16c5203e9dcf3 530 PANTHER PTHR10110:SF86 425 501 4.7E-95 T 23-04-2016 DC74_RS12475 18064264496f687194d16c5203e9dcf3 530 Pfam PF00999 Sodium/hydrogen exchanger family 9 405 4.4E-57 T 23-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 DC74_RS12475 18064264496f687194d16c5203e9dcf3 530 PANTHER PTHR10110:SF86 4 408 4.7E-95 T 23-04-2016 DC74_RS27570 145af68ea53f0b59e24f5e058e983b7a 431 PANTHER PTHR23501:SF54 1 395 1.4E-161 T 23-04-2016 DC74_RS27570 145af68ea53f0b59e24f5e058e983b7a 431 SUPERFAMILY SSF103473 2 175 1.05E-51 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS27570 145af68ea53f0b59e24f5e058e983b7a 431 SUPERFAMILY SSF103473 225 430 1.05E-51 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS27570 145af68ea53f0b59e24f5e058e983b7a 431 PANTHER PTHR23501 1 395 1.4E-161 T 23-04-2016 DC74_RS27570 145af68ea53f0b59e24f5e058e983b7a 431 Gene3D G3DSA:1.20.1250.20 246 421 1.1E-14 T 23-04-2016 DC74_RS27570 145af68ea53f0b59e24f5e058e983b7a 431 Pfam PF07690 Major Facilitator Superfamily 3 387 9.6E-39 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS27570 145af68ea53f0b59e24f5e058e983b7a 431 Gene3D G3DSA:1.20.1250.20 3 165 3.8E-19 T 23-04-2016 DC74_RS09155 13b9824f8c73b5e360a3e7b5bc148087 420 SUPERFAMILY SSF56059 91 336 1.56E-37 T 23-04-2016 DC74_RS09155 13b9824f8c73b5e360a3e7b5bc148087 420 Gene3D G3DSA:3.30.470.20 104 334 4.1E-31 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS09155 13b9824f8c73b5e360a3e7b5bc148087 420 Pfam PF13535 ATP-grasp domain 144 301 2.0E-17 T 23-04-2016 DC74_RS06250 24327b654ed5af36c2d0d193c885f148 472 PANTHER PTHR11785 11 465 9.8E-193 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS06250 24327b654ed5af36c2d0d193c885f148 472 ProSitePatterns PS00218 Amino acid permeases signature. 56 86 - T 23-04-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 DC74_RS06250 24327b654ed5af36c2d0d193c885f148 472 Pfam PF00324 Amino acid permease 31 436 2.4E-101 T 23-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 DC74_RS06250 24327b654ed5af36c2d0d193c885f148 472 PANTHER PTHR11785:SF386 11 465 9.8E-193 T 23-04-2016 DC74_RS06250 24327b654ed5af36c2d0d193c885f148 472 PIRSF PIRSF006060 2 466 9.9E-69 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS25845 b2e0c9eb679d5731e3a64f7eae29c1d8 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 321 3.9E-32 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS25845 b2e0c9eb679d5731e3a64f7eae29c1d8 323 PANTHER PTHR30465:SF56 1 322 4.8E-149 T 23-04-2016 DC74_RS25845 b2e0c9eb679d5731e3a64f7eae29c1d8 323 PANTHER PTHR30465 1 322 4.8E-149 T 23-04-2016 DC74_RS25845 b2e0c9eb679d5731e3a64f7eae29c1d8 323 SUPERFAMILY SSF161098 98 307 2.18E-12 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS25845 b2e0c9eb679d5731e3a64f7eae29c1d8 323 Gene3D G3DSA:1.10.3720.10 95 314 7.3E-12 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS07185 aed969d627b62ce54d92a5df8f73b648 933 Gene3D G3DSA:3.40.50.2300 601 702 1.3E-7 T 23-04-2016 DC74_RS07185 aed969d627b62ce54d92a5df8f73b648 933 SUPERFAMILY SSF53822 602 882 6.48E-12 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS39740 1e64a37d3ff01ab1cd54f4394dcd13ab 380 SUPERFAMILY SSF51679 4 363 2.22E-90 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS39740 1e64a37d3ff01ab1cd54f4394dcd13ab 380 Gene3D G3DSA:3.20.20.30 294 361 1.2E-97 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS39740 1e64a37d3ff01ab1cd54f4394dcd13ab 380 Gene3D G3DSA:3.20.20.30 3 260 1.2E-97 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS39740 1e64a37d3ff01ab1cd54f4394dcd13ab 380 PANTHER PTHR30011:SF1 1 356 3.7E-131 T 23-04-2016 DC74_RS39740 1e64a37d3ff01ab1cd54f4394dcd13ab 380 Pfam PF00296 Luciferase-like monooxygenase 4 332 1.6E-85 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS39740 1e64a37d3ff01ab1cd54f4394dcd13ab 380 PANTHER PTHR30011 1 356 3.7E-131 T 23-04-2016 DC74_RS29120 ef5b9820438f8dfc1d9315a26152c7ab 446 SUPERFAMILY SSF56176 18 195 7.36E-45 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS29120 ef5b9820438f8dfc1d9315a26152c7ab 446 PANTHER PTHR13878 18 445 1.6E-100 T 23-04-2016 DC74_RS29120 ef5b9820438f8dfc1d9315a26152c7ab 446 Gene3D G3DSA:3.30.43.10 17 86 1.1E-21 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS29120 ef5b9820438f8dfc1d9315a26152c7ab 446 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 30 63 - T 23-04-2016 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 DC74_RS29120 ef5b9820438f8dfc1d9315a26152c7ab 446 Pfam PF04030 D-arabinono-1,4-lactone oxidase 190 442 6.5E-78 T 23-04-2016 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 DC74_RS29120 ef5b9820438f8dfc1d9315a26152c7ab 446 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 19 445 1.1E-117 T 23-04-2016 DC74_RS29120 ef5b9820438f8dfc1d9315a26152c7ab 446 PANTHER PTHR13878:SF63 18 445 1.6E-100 T 23-04-2016 DC74_RS29120 ef5b9820438f8dfc1d9315a26152c7ab 446 Gene3D G3DSA:3.30.465.10 87 195 5.0E-29 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS29120 ef5b9820438f8dfc1d9315a26152c7ab 446 PIRSF PIRSF000136 13 446 3.4E-109 T 23-04-2016 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 DC74_RS29120 ef5b9820438f8dfc1d9315a26152c7ab 446 Pfam PF01565 FAD binding domain 30 165 1.9E-30 T 23-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DC74_RS32090 f7a8b423f9cf79c3d7c210b83dfc0ac4 572 SUPERFAMILY SSF52518 382 564 4.98E-48 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS32090 f7a8b423f9cf79c3d7c210b83dfc0ac4 572 Gene3D G3DSA:3.40.50.970 378 563 6.3E-51 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS32090 f7a8b423f9cf79c3d7c210b83dfc0ac4 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 212 338 9.9E-24 T 23-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DC74_RS32090 f7a8b423f9cf79c3d7c210b83dfc0ac4 572 SUPERFAMILY SSF52518 22 195 4.49E-46 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS32090 f7a8b423f9cf79c3d7c210b83dfc0ac4 572 SUPERFAMILY SSF52467 207 387 8.47E-34 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS32090 f7a8b423f9cf79c3d7c210b83dfc0ac4 572 Gene3D G3DSA:3.40.50.970 22 191 1.2E-57 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS32090 f7a8b423f9cf79c3d7c210b83dfc0ac4 572 PANTHER PTHR18968:SF6 1 572 9.2E-153 T 23-04-2016 DC74_RS32090 f7a8b423f9cf79c3d7c210b83dfc0ac4 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 22 188 1.1E-49 T 23-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DC74_RS32090 f7a8b423f9cf79c3d7c210b83dfc0ac4 572 Gene3D G3DSA:3.40.50.1220 203 347 1.8E-35 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS32090 f7a8b423f9cf79c3d7c210b83dfc0ac4 572 PANTHER PTHR18968 1 572 9.2E-153 T 23-04-2016 DC74_RS32090 f7a8b423f9cf79c3d7c210b83dfc0ac4 572 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 442 461 - T 23-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 DC74_RS32090 f7a8b423f9cf79c3d7c210b83dfc0ac4 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 406 554 1.1E-28 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS29665 a4572ea371fbf9a850cc6287d1872823 406 PANTHER PTHR22683:SF41 145 397 3.5E-34 T 23-04-2016 DC74_RS29665 a4572ea371fbf9a850cc6287d1872823 406 PANTHER PTHR22683 145 397 3.5E-34 T 23-04-2016 DC74_RS29665 a4572ea371fbf9a850cc6287d1872823 406 Pfam PF00589 Phage integrase family 186 388 1.8E-14 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS29665 a4572ea371fbf9a850cc6287d1872823 406 SUPERFAMILY SSF56349 74 391 1.3E-46 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DC74_RS29665 a4572ea371fbf9a850cc6287d1872823 406 Gene3D G3DSA:1.10.443.10 175 392 1.4E-31 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS29665 a4572ea371fbf9a850cc6287d1872823 406 Gene3D G3DSA:1.10.150.130 79 159 3.8E-10 T 23-04-2016 IPR023109 Integrase/recombinase, N-terminal DC74_RS03640 8dedab94e265291d119cbe6e6d4cf29e 270 Pfam PF08241 Methyltransferase domain 55 145 2.2E-9 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS03640 8dedab94e265291d119cbe6e6d4cf29e 270 SUPERFAMILY SSF53335 16 206 1.26E-21 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS03640 8dedab94e265291d119cbe6e6d4cf29e 270 Gene3D G3DSA:3.40.50.150 36 210 1.9E-17 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 Gene3D G3DSA:3.30.365.10 195 299 8.5E-29 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 Gene3D G3DSA:3.90.1170.50 16 130 8.4E-40 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 PANTHER PTHR11908:SF95 615 792 3.2E-254 T 23-04-2016 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 PANTHER PTHR11908:SF95 474 594 3.2E-254 T 23-04-2016 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 PANTHER PTHR11908:SF95 21 458 3.2E-254 T 23-04-2016 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 SUPERFAMILY SSF56003 134 792 1.06E-152 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 Gene3D G3DSA:3.30.365.10 302 376 7.8E-40 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 Gene3D G3DSA:3.30.365.10 131 194 7.8E-40 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 35 142 1.0E-33 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 SMART SM01008 35 142 9.5E-45 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 Gene3D G3DSA:3.30.365.10 481 625 1.5E-26 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 173 737 3.2E-145 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 Gene3D G3DSA:3.30.365.10 653 792 3.3E-55 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 Gene3D G3DSA:3.30.365.10 378 480 3.3E-55 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 SUPERFAMILY SSF54665 19 163 1.57E-41 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 PANTHER PTHR11908 615 792 3.2E-254 T 23-04-2016 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 PANTHER PTHR11908 474 594 3.2E-254 T 23-04-2016 DC74_RS31165 6dc64e22916a8c8edb6f24ef4d3e05c9 795 PANTHER PTHR11908 21 458 3.2E-254 T 23-04-2016 DC74_RS20835 a250c2c8c48725e471c5ef6e0f1ba4c2 148 Gene3D G3DSA:3.40.5.10 1 51 7.8E-22 T 23-04-2016 IPR020070 Ribosomal protein L9, N-terminal DC74_RS20835 a250c2c8c48725e471c5ef6e0f1ba4c2 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.608 T 23-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20835 a250c2c8c48725e471c5ef6e0f1ba4c2 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 147 7.6E-29 T 23-04-2016 IPR020069 Ribosomal protein L9, C-terminal DC74_RS20835 a250c2c8c48725e471c5ef6e0f1ba4c2 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.8E-39 T 23-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20835 a250c2c8c48725e471c5ef6e0f1ba4c2 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 23-04-2016 IPR020070 Ribosomal protein L9, N-terminal DC74_RS20835 a250c2c8c48725e471c5ef6e0f1ba4c2 148 SUPERFAMILY SSF55653 58 147 2.22E-25 T 23-04-2016 IPR020069 Ribosomal protein L9, C-terminal DC74_RS20835 a250c2c8c48725e471c5ef6e0f1ba4c2 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 4.7E-21 T 23-04-2016 IPR020070 Ribosomal protein L9, N-terminal DC74_RS20835 a250c2c8c48725e471c5ef6e0f1ba4c2 148 SUPERFAMILY SSF55658 1 56 5.76E-17 T 23-04-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal DC74_RS20835 a250c2c8c48725e471c5ef6e0f1ba4c2 148 PANTHER PTHR21368 1 147 2.2E-46 T 23-04-2016 IPR000244 Ribosomal protein L9 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20835 a250c2c8c48725e471c5ef6e0f1ba4c2 148 Gene3D G3DSA:3.10.430.100 62 147 3.4E-30 T 23-04-2016 IPR020069 Ribosomal protein L9, C-terminal DC74_RS20435 68b6412e781ecd09f02bbf3cd7d44e3f 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 4.8E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS20435 68b6412e781ecd09f02bbf3cd7d44e3f 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 4.8E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS20435 68b6412e781ecd09f02bbf3cd7d44e3f 196 PANTHER PTHR30055:SF57 9 170 2.2E-67 T 23-04-2016 DC74_RS20435 68b6412e781ecd09f02bbf3cd7d44e3f 196 SUPERFAMILY SSF46689 2 86 1.59E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS20435 68b6412e781ecd09f02bbf3cd7d44e3f 196 PANTHER PTHR30055 9 170 2.2E-67 T 23-04-2016 DC74_RS20435 68b6412e781ecd09f02bbf3cd7d44e3f 196 SUPERFAMILY SSF48498 82 194 1.88E-19 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS20435 68b6412e781ecd09f02bbf3cd7d44e3f 196 Gene3D G3DSA:1.10.357.10 60 195 4.8E-47 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS20435 68b6412e781ecd09f02bbf3cd7d44e3f 196 Gene3D G3DSA:1.10.10.60 2 59 3.1E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS20435 68b6412e781ecd09f02bbf3cd7d44e3f 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 9.0E-16 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS17245 f29beeaf7a98c6ea9a5b0d6d15152aa1 282 Pfam PF12698 ABC-2 family transporter protein 58 252 2.8E-21 T 23-04-2016 DC74_RS17245 f29beeaf7a98c6ea9a5b0d6d15152aa1 282 PRINTS PR00164 ABC-2 type transport system membrane protein signature 102 127 4.9E-5 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS17245 f29beeaf7a98c6ea9a5b0d6d15152aa1 282 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 4.9E-5 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS17245 f29beeaf7a98c6ea9a5b0d6d15152aa1 282 PRINTS PR00164 ABC-2 type transport system membrane protein signature 195 214 4.9E-5 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS17245 f29beeaf7a98c6ea9a5b0d6d15152aa1 282 PRINTS PR00164 ABC-2 type transport system membrane protein signature 175 194 4.9E-5 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS17245 f29beeaf7a98c6ea9a5b0d6d15152aa1 282 PIRSF PIRSF006648 12 263 1.8E-18 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS17245 f29beeaf7a98c6ea9a5b0d6d15152aa1 282 PANTHER PTHR30294 14 268 3.1E-26 T 23-04-2016 DC74_RS22635 94236a013ac49d3bb5802ceba99ab84c 230 PANTHER PTHR10245 16 223 1.9E-37 T 23-04-2016 DC74_RS22635 94236a013ac49d3bb5802ceba99ab84c 230 PANTHER PTHR10245:SF7 16 223 1.9E-37 T 23-04-2016 DC74_RS25955 2514c5183afa87fe9c43a3583de1e3ec 147 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 54 84 1.3E-7 T 23-04-2016 IPR019933 DivIVA domain DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 Pfam PF00498 FHA domain 189 255 2.1E-16 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 SMART SM00382 302 496 8.7E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 Gene3D G3DSA:2.60.200.20 13 90 2.6E-22 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 SUPERFAMILY SSF49879 12 90 4.59E-22 T 23-04-2016 IPR008984 SMAD/FHA domain GO:0005515 DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 Pfam PF00005 ABC transporter 293 440 2.2E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 SUPERFAMILY SSF49879 131 283 3.25E-30 T 23-04-2016 IPR008984 SMAD/FHA domain GO:0005515 DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 SMART SM00240 24 74 7.1E-11 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 SMART SM00240 187 238 1.2E-14 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 PANTHER PTHR19241:SF189 263 838 7.0E-100 T 23-04-2016 DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 SUPERFAMILY SSF52540 271 511 1.02E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 Pfam PF01061 ABC-2 type transporter 565 779 7.3E-17 T 23-04-2016 IPR013525 ABC-2 type transporter GO:0016020 DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 Gene3D G3DSA:2.60.200.20 125 278 5.7E-26 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 ProSitePatterns PS00211 ABC transporters family signature. 412 426 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 Gene3D G3DSA:3.40.50.300 279 503 3.3E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 13 89 9.4E-17 T 23-04-2016 IPR032030 YscD, cytoplasmic domain DC74_RS11285 b407ad131c465ecb77cd1925c0d74e3a 839 PANTHER PTHR19241 263 838 7.0E-100 T 23-04-2016 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 PRINTS PR00463 E-class P450 group I signature 263 280 3.6E-18 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 PRINTS PR00463 E-class P450 group I signature 283 309 3.6E-18 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 PRINTS PR00463 E-class P450 group I signature 369 393 3.6E-18 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 PRINTS PR00463 E-class P450 group I signature 414 437 3.6E-18 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 PRINTS PR00463 E-class P450 group I signature 404 414 3.6E-18 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 PRINTS PR00463 E-class P450 group I signature 40 59 3.6E-18 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 Pfam PF00067 Cytochrome P450 32 458 3.4E-70 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 Pfam PF00667 FAD binding domain 692 878 1.3E-24 T 23-04-2016 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 SUPERFAMILY SSF52343 907 1061 1.44E-36 T 23-04-2016 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 SUPERFAMILY SSF48264 30 465 1.44E-91 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 Gene3D G3DSA:1.10.630.10 30 469 4.8E-99 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 Pfam PF00175 Oxidoreductase NAD-binding domain 919 1025 2.2E-11 T 23-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 Gene3D G3DSA:2.40.30.10 854 917 1.0E-13 T 23-04-2016 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 Gene3D G3DSA:2.40.30.10 691 726 1.0E-13 T 23-04-2016 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 Gene3D G3DSA:3.40.50.360 511 653 1.5E-30 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 Gene3D G3DSA:3.40.50.80 918 1062 8.4E-42 T 23-04-2016 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 SUPERFAMILY SSF63380 690 902 5.88E-44 T 23-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 Gene3D G3DSA:1.20.990.10 727 853 3.0E-18 T 23-04-2016 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 Pfam PF00258 Flavodoxin 514 644 8.4E-20 T 23-04-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 407 416 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 PIRSF PIRSF000209 13 1064 5.4E-302 T 23-04-2016 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 PANTHER PTHR19384 405 1062 8.6E-128 T 23-04-2016 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 PRINTS PR00385 P450 superfamily signature 329 340 1.9E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 PRINTS PR00385 P450 superfamily signature 405 414 1.9E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 PRINTS PR00385 P450 superfamily signature 274 291 1.9E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 PRINTS PR00385 P450 superfamily signature 414 425 1.9E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33680 c948f6f69b6509b60ea2b4a8dd631028 1064 SUPERFAMILY SSF52218 509 654 2.65E-30 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS38875 c30dc48349dd530352e90e6bd76976c5 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS38875 c30dc48349dd530352e90e6bd76976c5 347 PANTHER PTHR11695 12 347 4.0E-104 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS38875 c30dc48349dd530352e90e6bd76976c5 347 Gene3D G3DSA:3.90.180.10 1 174 8.1E-47 T 23-04-2016 IPR011032 GroES-like DC74_RS38875 c30dc48349dd530352e90e6bd76976c5 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 133 3.1E-25 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS38875 c30dc48349dd530352e90e6bd76976c5 347 PANTHER PTHR11695:SF601 12 347 4.0E-104 T 23-04-2016 DC74_RS38875 c30dc48349dd530352e90e6bd76976c5 347 Pfam PF00107 Zinc-binding dehydrogenase 183 292 4.3E-17 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS38875 c30dc48349dd530352e90e6bd76976c5 347 SUPERFAMILY SSF50129 1 176 6.85E-49 T 23-04-2016 IPR011032 GroES-like DC74_RS38875 c30dc48349dd530352e90e6bd76976c5 347 Gene3D G3DSA:3.40.50.720 175 292 1.1E-29 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38875 c30dc48349dd530352e90e6bd76976c5 347 SUPERFAMILY SSF51735 152 310 9.7E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 Pfam PF00970 Oxidoreductase FAD-binding domain 41 107 1.4E-5 T 23-04-2016 IPR008333 Oxidoreductase, FAD-binding domain DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 SUPERFAMILY SSF52343 103 233 5.11E-24 T 23-04-2016 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 255 323 2.2E-9 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 SUPERFAMILY SSF54292 217 329 2.75E-23 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 Gene3D G3DSA:3.40.50.80 107 224 4.7E-21 T 23-04-2016 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 281 289 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 PANTHER PTHR22924 26 288 2.8E-67 T 23-04-2016 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 SUPERFAMILY SSF63380 21 105 2.87E-25 T 23-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 195 203 8.9E-29 T 23-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 116 135 8.9E-29 T 23-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 35 45 8.9E-29 T 23-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 81 95 8.9E-29 T 23-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 57 71 8.9E-29 T 23-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 45 57 8.9E-29 T 23-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 Gene3D G3DSA:2.40.30.10 21 106 1.2E-30 T 23-04-2016 DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 Gene3D G3DSA:3.10.20.30 225 329 1.8E-23 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS38565 9ea80be80396fb6db94d24e7e4968fe1 332 PANTHER PTHR22924:SF20 26 288 2.8E-67 T 23-04-2016 DC74_RS26355 ec943553b62ccbfb577a3f902bb2f43c 276 SUPERFAMILY SSF143081 2 265 5.23E-64 T 23-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS26355 ec943553b62ccbfb577a3f902bb2f43c 276 PANTHER PTHR13604 2 268 7.8E-73 T 23-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS26355 ec943553b62ccbfb577a3f902bb2f43c 276 Gene3D G3DSA:3.90.1680.10 1 266 5.0E-73 T 23-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS26355 ec943553b62ccbfb577a3f902bb2f43c 276 Pfam PF02586 SOS response associated peptidase (SRAP) 1 256 1.6E-64 T 23-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS35870 70e3e3d5ed5a4d3432245e877607703f 193 Pfam PF01750 Hydrogenase maturation protease 32 165 1.5E-15 T 23-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DC74_RS35870 70e3e3d5ed5a4d3432245e877607703f 193 PANTHER PTHR30302 9 183 1.8E-32 T 23-04-2016 DC74_RS35870 70e3e3d5ed5a4d3432245e877607703f 193 Gene3D G3DSA:3.40.50.1450 13 168 4.5E-44 T 23-04-2016 IPR023430 Peptidase HybD-like domain DC74_RS35870 70e3e3d5ed5a4d3432245e877607703f 193 SUPERFAMILY SSF53163 13 168 1.83E-34 T 23-04-2016 IPR023430 Peptidase HybD-like domain DC74_RS35870 70e3e3d5ed5a4d3432245e877607703f 193 PRINTS PR00446 Hydrogen uptake protein signature 45 62 9.5E-14 T 23-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DC74_RS35870 70e3e3d5ed5a4d3432245e877607703f 193 PRINTS PR00446 Hydrogen uptake protein signature 26 37 9.5E-14 T 23-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DC74_RS35870 70e3e3d5ed5a4d3432245e877607703f 193 PRINTS PR00446 Hydrogen uptake protein signature 14 26 9.5E-14 T 23-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DC74_RS35870 70e3e3d5ed5a4d3432245e877607703f 193 PRINTS PR00446 Hydrogen uptake protein signature 78 94 9.5E-14 T 23-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DC74_RS35870 70e3e3d5ed5a4d3432245e877607703f 193 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 15 165 1.1E-34 T 23-04-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DC74_RS01715 fc87ba690cae1d049fc13ea6ed82c3bb 206 PANTHER PTHR30055:SF54 6 195 1.5E-45 T 23-04-2016 DC74_RS01715 fc87ba690cae1d049fc13ea6ed82c3bb 206 SUPERFAMILY SSF46689 12 85 9.98E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01715 fc87ba690cae1d049fc13ea6ed82c3bb 206 Gene3D G3DSA:1.10.357.10 66 194 1.0E-13 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS01715 fc87ba690cae1d049fc13ea6ed82c3bb 206 Gene3D G3DSA:1.10.10.60 13 65 9.4E-22 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01715 fc87ba690cae1d049fc13ea6ed82c3bb 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 68 6.3E-17 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01715 fc87ba690cae1d049fc13ea6ed82c3bb 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 2.3E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01715 fc87ba690cae1d049fc13ea6ed82c3bb 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.3E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01715 fc87ba690cae1d049fc13ea6ed82c3bb 206 PANTHER PTHR30055 6 195 1.5E-45 T 23-04-2016 DC74_RS02775 b83535fa05d14ac36bc413956344240a 499 SUPERFAMILY SSF56601 45 369 1.39E-80 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS02775 b83535fa05d14ac36bc413956344240a 499 PANTHER PTHR22935 10 380 4.2E-72 T 23-04-2016 DC74_RS02775 b83535fa05d14ac36bc413956344240a 499 Pfam PF00144 Beta-lactamase 47 359 5.3E-73 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS02775 b83535fa05d14ac36bc413956344240a 499 Gene3D G3DSA:3.40.710.10 31 373 6.8E-81 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS06130 b92eb1f0adb00085b9f4821d29238390 344 Pfam PF01032 FecCD transport family 32 339 1.1E-85 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS06130 b92eb1f0adb00085b9f4821d29238390 344 PANTHER PTHR30472:SF31 9 344 2.7E-112 T 23-04-2016 DC74_RS06130 b92eb1f0adb00085b9f4821d29238390 344 PANTHER PTHR30472 9 344 2.7E-112 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS06130 b92eb1f0adb00085b9f4821d29238390 344 Gene3D G3DSA:1.10.3470.10 15 341 1.4E-91 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS06130 b92eb1f0adb00085b9f4821d29238390 344 SUPERFAMILY SSF81345 14 339 4.84E-73 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS00340 486d4057158254fc535093edc22198fe 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.1E-5 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00340 486d4057158254fc535093edc22198fe 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.1E-5 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00340 486d4057158254fc535093edc22198fe 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.1E-5 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00340 486d4057158254fc535093edc22198fe 300 Gene3D G3DSA:1.10.10.10 8 84 3.3E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00340 486d4057158254fc535093edc22198fe 300 Gene3D G3DSA:3.40.190.10 173 267 3.7E-11 T 23-04-2016 DC74_RS00340 486d4057158254fc535093edc22198fe 300 Pfam PF03466 LysR substrate binding domain 96 295 1.1E-6 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS00340 486d4057158254fc535093edc22198fe 300 PANTHER PTHR30118 11 291 4.1E-57 T 23-04-2016 DC74_RS00340 486d4057158254fc535093edc22198fe 300 PANTHER PTHR30118:SF4 11 291 4.1E-57 T 23-04-2016 DC74_RS00340 486d4057158254fc535093edc22198fe 300 SUPERFAMILY SSF46785 8 84 2.01E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00340 486d4057158254fc535093edc22198fe 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 2.2E-15 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00340 486d4057158254fc535093edc22198fe 300 Gene3D G3DSA:3.40.190.10 90 172 1.5E-13 T 23-04-2016 DC74_RS00340 486d4057158254fc535093edc22198fe 300 Gene3D G3DSA:3.40.190.10 273 298 1.5E-13 T 23-04-2016 DC74_RS00340 486d4057158254fc535093edc22198fe 300 SUPERFAMILY SSF53850 90 297 9.23E-22 T 23-04-2016 DC74_RS27400 c00afbbd749a105115f3623c80c3e4de 276 TIGRFAM TIGR00552 nadE: NAD+ synthetase 26 273 2.0E-61 T 23-04-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 DC74_RS27400 c00afbbd749a105115f3623c80c3e4de 276 PANTHER PTHR23090:SF7 10 276 6.0E-140 T 23-04-2016 DC74_RS27400 c00afbbd749a105115f3623c80c3e4de 276 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 23 276 32.088 T 23-04-2016 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 DC74_RS27400 c00afbbd749a105115f3623c80c3e4de 276 Gene3D G3DSA:3.40.50.620 11 273 2.8E-67 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS27400 c00afbbd749a105115f3623c80c3e4de 276 SUPERFAMILY SSF52402 10 274 1.62E-71 T 23-04-2016 DC74_RS27400 c00afbbd749a105115f3623c80c3e4de 276 PANTHER PTHR23090 10 276 6.0E-140 T 23-04-2016 DC74_RS27400 c00afbbd749a105115f3623c80c3e4de 276 Pfam PF02540 NAD synthase 29 273 1.2E-61 T 23-04-2016 IPR022310 NAD/GMP synthase DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 SUPERFAMILY SSF54909 75 147 7.51E-6 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 Gene3D G3DSA:1.10.10.10 200 244 1.0E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 SUPERFAMILY SSF46785 13 59 5.65E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 PANTHER PTHR30154 193 336 1.1E-29 T 23-04-2016 DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 198 214 1.8E-7 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 225 244 1.8E-7 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 214 225 1.8E-7 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 SUPERFAMILY SSF46785 198 247 8.54E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 SMART SM00344 198 303 4.4E-8 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 SMART SM00344 13 117 2.5E-4 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 Pfam PF13404 AsnC-type helix-turn-helix domain 14 52 1.3E-15 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 Pfam PF13404 AsnC-type helix-turn-helix domain 199 239 1.6E-11 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 Gene3D G3DSA:3.30.70.920 77 149 3.5E-8 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 Gene3D G3DSA:3.30.70.920 263 335 5.4E-10 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 PANTHER PTHR30154:SF12 193 336 1.1E-29 T 23-04-2016 DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 SUPERFAMILY SSF54909 257 336 4.42E-10 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 Gene3D G3DSA:1.10.10.10 13 52 3.1E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21155 eb136bbb0690830a71f595b89a046ca1 353 Pfam PF01037 Lrp/AsnC ligand binding domain 266 329 5.0E-10 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 60 74 1.4E-7 T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 191 211 1.4E-7 T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 149 171 1.4E-7 T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 SMART SM00839 163 389 1.0E-40 T 23-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 SUPERFAMILY SSF51735 158 378 4.51E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 158 324 9.9E-34 T 23-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 Gene3D G3DSA:3.40.50.720 166 324 1.1E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 PANTHER PTHR11606 38 324 2.9E-33 T 23-04-2016 DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 PIRSF PIRSF000185 5 386 2.4E-77 T 23-04-2016 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 Gene3D G3DSA:3.40.192.10 9 125 2.5E-19 T 23-04-2016 DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 68 81 - T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 16 100 1.1E-8 T 23-04-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 DC74_RS29520 10b11a31776a20c71d26871e9e541f88 390 SUPERFAMILY SSF53223 3 127 6.08E-21 T 23-04-2016 DC74_RS24060 9da2091521d154e982f6b87ea2764731 152 SMART SM01007 32 152 2.3E-12 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal DC74_RS24060 9da2091521d154e982f6b87ea2764731 152 PANTHER PTHR10672 10 152 8.5E-74 T 23-04-2016 DC74_RS24060 9da2091521d154e982f6b87ea2764731 152 Gene3D G3DSA:3.40.225.10 26 150 7.7E-41 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal DC74_RS24060 9da2091521d154e982f6b87ea2764731 152 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 33 149 3.1E-33 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal DC74_RS24060 9da2091521d154e982f6b87ea2764731 152 PANTHER PTHR10672:SF17 10 152 8.5E-74 T 23-04-2016 DC74_RS24060 9da2091521d154e982f6b87ea2764731 152 SUPERFAMILY SSF53639 25 152 3.14E-41 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal DC74_RS09570 798feadbf236f9ec4dda35c3bc602570 238 SMART SM00849 12 202 6.8E-37 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS09570 798feadbf236f9ec4dda35c3bc602570 238 Pfam PF00753 Metallo-beta-lactamase superfamily 9 202 4.3E-29 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS09570 798feadbf236f9ec4dda35c3bc602570 238 Gene3D G3DSA:3.60.15.10 9 220 2.9E-50 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS09570 798feadbf236f9ec4dda35c3bc602570 238 SUPERFAMILY SSF56281 6 226 1.19E-49 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS09570 798feadbf236f9ec4dda35c3bc602570 238 PANTHER PTHR11935 1 220 6.6E-55 T 23-04-2016 DC74_RS09570 798feadbf236f9ec4dda35c3bc602570 238 PANTHER PTHR11935:SF8 1 220 6.6E-55 T 23-04-2016 DC74_RS38625 414f1dfeba2b099fd4aee53c3da66e5c 311 PANTHER PTHR12128 13 304 4.3E-75 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS38625 414f1dfeba2b099fd4aee53c3da66e5c 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 142 159 1.3E-6 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS38625 414f1dfeba2b099fd4aee53c3da66e5c 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 118 134 1.3E-6 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS38625 414f1dfeba2b099fd4aee53c3da66e5c 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 50 71 1.3E-6 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS38625 414f1dfeba2b099fd4aee53c3da66e5c 311 SMART SM01130 10 302 3.2E-83 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS38625 414f1dfeba2b099fd4aee53c3da66e5c 311 SUPERFAMILY SSF51569 11 300 2.93E-75 T 23-04-2016 DC74_RS38625 414f1dfeba2b099fd4aee53c3da66e5c 311 Gene3D G3DSA:3.20.20.70 10 303 1.8E-80 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS38625 414f1dfeba2b099fd4aee53c3da66e5c 311 Pfam PF00701 Dihydrodipicolinate synthetase family 33 299 4.9E-45 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS38625 414f1dfeba2b099fd4aee53c3da66e5c 311 PIRSF PIRSF001365 12 310 5.0E-71 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SUPERFAMILY SSF50978 1081 1302 3.84E-68 T 23-04-2016 IPR017986 WD40-repeat-containing domain GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SUPERFAMILY SSF50978 1039 1054 3.84E-68 T 23-04-2016 IPR017986 WD40-repeat-containing domain GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SUPERFAMILY SSF50978 862 999 3.84E-68 T 23-04-2016 IPR017986 WD40-repeat-containing domain GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Gene3D G3DSA:2.130.10.10 863 1026 1.8E-42 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Gene3D G3DSA:2.130.10.10 679 860 2.3E-54 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 745 759 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Gene3D G3DSA:3.40.50.300 149 197 2.5E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 PRINTS PR00320 G protein beta WD-40 repeat signature 882 896 9.9E-9 T 23-04-2016 IPR020472 G-protein beta WD-40 repeat DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 PRINTS PR00320 G protein beta WD-40 repeat signature 745 759 9.9E-9 T 23-04-2016 IPR020472 G-protein beta WD-40 repeat DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 PRINTS PR00320 G protein beta WD-40 repeat signature 1196 1210 9.9E-9 T 23-04-2016 IPR020472 G-protein beta WD-40 repeat DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 PANTHER PTHR22847 689 1050 5.3E-145 T 23-04-2016 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 699 713 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1150 1164 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 882 896 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 PANTHER PTHR22847 1101 1299 5.3E-145 T 23-04-2016 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1196 1210 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SUPERFAMILY SSF50978 673 1021 2.75E-84 T 23-04-2016 IPR017986 WD40-repeat-containing domain GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 719 758 2.8E-10 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 1082 1117 0.05 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 1264 1301 4.0 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 1027 1069 28.0 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 856 895 3.0E-11 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 902 941 4.4E-8 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 765 804 1.2E-5 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 673 712 3.6E-8 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 1170 1209 1.6E-8 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 810 849 6.0E-10 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 1124 1163 1.8E-10 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 948 987 1.6E-5 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 990 1020 10.0 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SMART SM00320 1216 1255 1.0E-7 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Gene3D G3DSA:2.130.10.10 1037 1319 5.4E-65 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 836 850 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Pfam PF00400 WD domain, G-beta repeat 680 712 1.4E-5 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Pfam PF00400 WD domain, G-beta repeat 963 987 0.0037 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Pfam PF00400 WD domain, G-beta repeat 1223 1255 1.3E-6 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Pfam PF00400 WD domain, G-beta repeat 1131 1163 1.5E-8 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Pfam PF00400 WD domain, G-beta repeat 725 758 2.2E-8 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Pfam PF00400 WD domain, G-beta repeat 814 849 3.5E-7 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Pfam PF00400 WD domain, G-beta repeat 1177 1209 1.0E-7 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Pfam PF00400 WD domain, G-beta repeat 862 895 1.2E-9 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Pfam PF00400 WD domain, G-beta repeat 773 804 0.0014 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Pfam PF00400 WD domain, G-beta repeat 1095 1117 0.23 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 Pfam PF00400 WD domain, G-beta repeat 908 941 7.6E-6 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 SUPERFAMILY SSF52540 153 385 1.65E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 PANTHER PTHR22847:SF50 1101 1299 5.3E-145 T 23-04-2016 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 PANTHER PTHR22847 34 63 5.3E-145 T 23-04-2016 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 928 942 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 PANTHER PTHR22847:SF50 34 63 5.3E-145 T 23-04-2016 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 PANTHER PTHR22847:SF50 689 1050 5.3E-145 T 23-04-2016 DC74_RS21990 4b5ac98dfe490ac7bf005a47bf164912 1339 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1242 1256 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS04135 f6cbb08b544f379f1e856cc9109356ca 207 PANTHER PTHR19372 15 201 1.2E-54 T 23-04-2016 DC74_RS04135 f6cbb08b544f379f1e856cc9109356ca 207 SUPERFAMILY SSF56524 16 204 3.66E-53 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS04135 f6cbb08b544f379f1e856cc9109356ca 207 Pfam PF00174 Oxidoreductase molybdopterin binding domain 34 182 1.5E-28 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS04135 f6cbb08b544f379f1e856cc9109356ca 207 Gene3D G3DSA:3.90.420.10 11 199 4.7E-44 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 Pfam PF00365 Phosphofructokinase 2 297 2.5E-102 T 23-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 PANTHER PTHR13697 1 336 1.7E-133 T 23-04-2016 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 23-04-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 SUPERFAMILY SSF53784 1 332 4.84E-120 T 23-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 Gene3D G3DSA:3.40.50.450 1 213 2.2E-74 T 23-04-2016 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 5.3E-75 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 5.3E-75 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 5.3E-75 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 5.3E-75 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 5.3E-75 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 5.3E-75 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 5.3E-75 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 5.3E-75 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 5.3E-75 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 42.882 T 23-04-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 PIRSF PIRSF000532 1 339 4.3E-116 T 23-04-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS35675 d806926cc38c3a6990794d1cbd201f3d 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 4.3E-146 T 23-04-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS05975 39cfd4e057451463dc2a8d2b060417ed 382 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 2.6E-9 T 23-04-2016 DC74_RS05975 39cfd4e057451463dc2a8d2b060417ed 382 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.6E-9 T 23-04-2016 DC74_RS05975 39cfd4e057451463dc2a8d2b060417ed 382 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 157 2.4E-5 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS05975 39cfd4e057451463dc2a8d2b060417ed 382 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 2.4E-5 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS05975 39cfd4e057451463dc2a8d2b060417ed 382 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 93 101 2.4E-5 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS05975 39cfd4e057451463dc2a8d2b060417ed 382 Gene3D G3DSA:3.50.50.60 146 294 1.7E-12 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS05975 39cfd4e057451463dc2a8d2b060417ed 382 PANTHER PTHR10632:SF8 3 141 1.0E-11 T 23-04-2016 DC74_RS05975 39cfd4e057451463dc2a8d2b060417ed 382 PANTHER PTHR10632 3 141 1.0E-11 T 23-04-2016 DC74_RS05975 39cfd4e057451463dc2a8d2b060417ed 382 SUPERFAMILY SSF51905 3 294 6.79E-24 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS05975 39cfd4e057451463dc2a8d2b060417ed 382 Gene3D G3DSA:3.50.50.60 3 145 8.2E-22 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS05975 39cfd4e057451463dc2a8d2b060417ed 382 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 271 4.6E-27 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 PANTHER PTHR11908 1 119 1.6E-140 T 23-04-2016 DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 Gene3D G3DSA:3.30.465.10 157 219 2.7E-35 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 Gene3D G3DSA:3.30.465.10 57 113 2.7E-35 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 Gene3D G3DSA:3.30.43.10 2 51 1.7E-19 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 SMART SM01092 226 324 6.5E-24 T 23-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 219 5.0E-53 T 23-04-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 227 322 1.6E-15 T 23-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 SUPERFAMILY SSF56176 2 219 1.85E-60 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 Gene3D G3DSA:3.30.390.50 224 327 3.7E-30 T 23-04-2016 DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 PANTHER PTHR11908:SF97 1 119 1.6E-140 T 23-04-2016 DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 PANTHER PTHR11908:SF97 162 330 1.6E-140 T 23-04-2016 DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 PANTHER PTHR11908 162 330 1.6E-140 T 23-04-2016 DC74_RS30955 b39fac46892c1633de991f8e0ff36efe 337 SUPERFAMILY SSF55447 224 325 1.44E-24 T 23-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal DC74_RS33670 7ea93c00ca4b6bb42c138e46bad08247 153 PRINTS PR01438 Universal stress protein signature 131 153 1.7E-6 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS33670 7ea93c00ca4b6bb42c138e46bad08247 153 PRINTS PR01438 Universal stress protein signature 16 34 1.7E-6 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS33670 7ea93c00ca4b6bb42c138e46bad08247 153 SUPERFAMILY SSF52402 19 153 3.1E-25 T 23-04-2016 DC74_RS33670 7ea93c00ca4b6bb42c138e46bad08247 153 PANTHER PTHR31964 1 153 8.2E-22 T 23-04-2016 DC74_RS33670 7ea93c00ca4b6bb42c138e46bad08247 153 Gene3D G3DSA:3.40.50.620 17 153 5.2E-26 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS33670 7ea93c00ca4b6bb42c138e46bad08247 153 Pfam PF00582 Universal stress protein family 17 153 9.1E-25 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS10610 66ed30088fcc15eee6fbcd3e15c5184f 203 SUPERFAMILY SSF48498 90 202 3.89E-19 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS10610 66ed30088fcc15eee6fbcd3e15c5184f 203 SUPERFAMILY SSF46689 19 94 8.72E-22 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS10610 66ed30088fcc15eee6fbcd3e15c5184f 203 Gene3D G3DSA:1.10.357.10 66 203 1.0E-39 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS10610 66ed30088fcc15eee6fbcd3e15c5184f 203 PANTHER PTHR30055 6 203 4.5E-65 T 23-04-2016 DC74_RS10610 66ed30088fcc15eee6fbcd3e15c5184f 203 Gene3D G3DSA:1.10.10.60 19 65 5.7E-24 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS10610 66ed30088fcc15eee6fbcd3e15c5184f 203 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 65 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS10610 66ed30088fcc15eee6fbcd3e15c5184f 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 6.7E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10610 66ed30088fcc15eee6fbcd3e15c5184f 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 6.7E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10610 66ed30088fcc15eee6fbcd3e15c5184f 203 PANTHER PTHR30055:SF33 6 203 4.5E-65 T 23-04-2016 DC74_RS10610 66ed30088fcc15eee6fbcd3e15c5184f 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 1.5E-22 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 SUPERFAMILY SSF46785 4 70 6.43E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 3.5E-18 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 3.4E-5 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 3.4E-5 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 Pfam PF07729 FCD domain 92 213 4.8E-24 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 SUPERFAMILY SSF48008 89 221 1.91E-26 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 PANTHER PTHR11751 86 108 4.2E-25 T 23-04-2016 DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 PANTHER PTHR11751 1 69 4.2E-25 T 23-04-2016 DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 PANTHER PTHR11751:SF342 86 108 4.2E-25 T 23-04-2016 DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 PANTHER PTHR11751:SF342 1 69 4.2E-25 T 23-04-2016 DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 Gene3D G3DSA:1.20.120.530 88 221 9.5E-27 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 SMART SM00345 7 66 8.6E-15 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 SMART SM00895 92 214 3.0E-19 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS10410 bc2c8a3663f22b788c4f12abebb6bcf9 223 Gene3D G3DSA:1.10.10.10 4 71 6.8E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09970 3aaedec3eaf96bea872686a6b1d8c5e4 471 PANTHER PTHR11751 77 466 4.7E-105 T 23-04-2016 DC74_RS09970 3aaedec3eaf96bea872686a6b1d8c5e4 471 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 49 1.6E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS09970 3aaedec3eaf96bea872686a6b1d8c5e4 471 SUPERFAMILY SSF46785 3 54 2.12E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09970 3aaedec3eaf96bea872686a6b1d8c5e4 471 Pfam PF00155 Aminotransferase class I and II 114 454 7.3E-21 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS09970 3aaedec3eaf96bea872686a6b1d8c5e4 471 Gene3D G3DSA:3.90.1150.10 355 459 6.1E-13 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS09970 3aaedec3eaf96bea872686a6b1d8c5e4 471 Gene3D G3DSA:1.10.10.10 3 56 3.0E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09970 3aaedec3eaf96bea872686a6b1d8c5e4 471 PANTHER PTHR11751:SF119 77 466 4.7E-105 T 23-04-2016 DC74_RS09970 3aaedec3eaf96bea872686a6b1d8c5e4 471 SMART SM00345 2 50 2.4E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS09970 3aaedec3eaf96bea872686a6b1d8c5e4 471 SUPERFAMILY SSF53383 93 465 2.18E-74 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS09970 3aaedec3eaf96bea872686a6b1d8c5e4 471 Gene3D G3DSA:3.40.640.10 134 348 6.0E-52 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS23950 204e3a49e91607d2a7744fb9fe1687e1 231 SMART SM00943 33 214 1.0E-29 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal DC74_RS23950 204e3a49e91607d2a7744fb9fe1687e1 231 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 33 202 5.9E-24 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal DC74_RS05030 f009a506e839bb0ff12e9ebf947c0124 289 PANTHER PTHR23309:SF24 1 289 2.7E-156 T 23-04-2016 DC74_RS05030 f009a506e839bb0ff12e9ebf947c0124 289 Gene3D G3DSA:1.10.1040.10 192 287 2.3E-33 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS05030 f009a506e839bb0ff12e9ebf947c0124 289 PANTHER PTHR23309 1 289 2.7E-156 T 23-04-2016 DC74_RS05030 f009a506e839bb0ff12e9ebf947c0124 289 SUPERFAMILY SSF48179 190 287 6.04E-31 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS05030 f009a506e839bb0ff12e9ebf947c0124 289 PIRSF PIRSF000105 1 289 3.6E-80 T 23-04-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 DC74_RS05030 f009a506e839bb0ff12e9ebf947c0124 289 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 284 1.6E-31 T 23-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS05030 f009a506e839bb0ff12e9ebf947c0124 289 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 187 1.7E-57 T 23-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS05030 f009a506e839bb0ff12e9ebf947c0124 289 Gene3D G3DSA:3.40.50.720 4 191 7.8E-57 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05030 f009a506e839bb0ff12e9ebf947c0124 289 SUPERFAMILY SSF51735 5 187 6.47E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02715 2b027b3ef7d9cdd26f41fc96ae7b4d91 408 SUPERFAMILY SSF51556 66 372 6.81E-56 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS02715 2b027b3ef7d9cdd26f41fc96ae7b4d91 408 Gene3D G3DSA:3.20.20.140 67 361 3.1E-79 T 23-04-2016 DC74_RS02715 2b027b3ef7d9cdd26f41fc96ae7b4d91 408 PANTHER PTHR32027:SF9 29 402 4.7E-72 T 23-04-2016 DC74_RS02715 2b027b3ef7d9cdd26f41fc96ae7b4d91 408 Gene3D G3DSA:2.30.40.10 10 66 8.2E-6 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS02715 2b027b3ef7d9cdd26f41fc96ae7b4d91 408 Gene3D G3DSA:2.30.40.10 363 403 8.2E-6 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS02715 2b027b3ef7d9cdd26f41fc96ae7b4d91 408 Pfam PF07969 Amidohydrolase family 168 402 2.3E-15 T 23-04-2016 IPR013108 Amidohydrolase 3 DC74_RS02715 2b027b3ef7d9cdd26f41fc96ae7b4d91 408 SUPERFAMILY SSF51338 363 406 2.29E-5 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS02715 2b027b3ef7d9cdd26f41fc96ae7b4d91 408 SUPERFAMILY SSF51338 26 64 2.29E-5 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS02715 2b027b3ef7d9cdd26f41fc96ae7b4d91 408 PANTHER PTHR32027 29 402 4.7E-72 T 23-04-2016 DC74_RS09955 6ba641ab27aee711c4dea50ec2a0ec6c 367 PANTHER PTHR10108 170 301 1.7E-21 T 23-04-2016 DC74_RS09955 6ba641ab27aee711c4dea50ec2a0ec6c 367 Pfam PF13847 Methyltransferase domain 187 301 5.6E-20 T 23-04-2016 IPR025714 Methyltransferase domain DC74_RS09955 6ba641ab27aee711c4dea50ec2a0ec6c 367 SUPERFAMILY SSF53335 156 295 1.75E-32 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS09955 6ba641ab27aee711c4dea50ec2a0ec6c 367 SUPERFAMILY SSF46785 42 111 1.44E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09955 6ba641ab27aee711c4dea50ec2a0ec6c 367 Gene3D G3DSA:3.40.50.150 166 350 4.6E-30 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS30770 400041b45ea708284be25b908e443c48 295 SUPERFAMILY SSF56112 46 293 1.83E-13 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS30770 400041b45ea708284be25b908e443c48 295 Gene3D G3DSA:3.30.200.20 48 135 5.8E-4 T 23-04-2016 DC74_RS30770 400041b45ea708284be25b908e443c48 295 Gene3D G3DSA:1.10.510.10 136 290 1.0E-4 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 SUPERFAMILY SSF56784 450 470 1.35E-57 T 23-04-2016 IPR023214 HAD-like domain DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 SUPERFAMILY SSF56784 515 755 1.35E-57 T 23-04-2016 IPR023214 HAD-like domain DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 655 671 1.8E-5 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 686 711 1.8E-5 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 PANTHER PTHR24093 1 771 4.7E-205 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 454 460 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 559 742 4.2E-39 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 227 496 8.3E-36 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 Pfam PF00702 haloacid dehalogenase-like hydrolase 448 669 8.1E-35 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 Gene3D G3DSA:3.40.50.1000 425 468 8.5E-51 T 23-04-2016 IPR023214 HAD-like domain DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 Gene3D G3DSA:3.40.50.1000 583 723 8.5E-51 T 23-04-2016 IPR023214 HAD-like domain DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 Gene3D G3DSA:3.30.70.100 1 59 3.0E-17 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 ProSitePatterns PS01229 Hypothetical cof family signature 2. 655 677 - T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 Gene3D G3DSA:3.40.1110.10 473 582 7.8E-9 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 452 466 4.0E-24 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 302 316 4.0E-24 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 580 591 4.0E-24 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 602 612 4.0E-24 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 678 690 4.0E-24 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 655 674 4.0E-24 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 Pfam PF00403 Heavy-metal-associated domain 1 53 5.2E-9 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 SUPERFAMILY SSF81653 263 352 7.59E-19 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 PANTHER PTHR24093:SF50 1 771 4.7E-205 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 Gene3D G3DSA:2.70.150.10 218 353 1.1E-18 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 Pfam PF00122 E1-E2 ATPase 225 443 4.4E-55 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 SUPERFAMILY SSF81665 704 732 3.66E-10 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 SUPERFAMILY SSF81665 353 446 3.66E-10 T 23-04-2016 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 SUPERFAMILY SSF55008 1 59 4.19E-12 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 DC74_RS07125 3329f4219455785053e2802a9bc1a485 787 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 170 757 1.7E-168 T 23-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 DC74_RS38780 2d9d4a7a932f7bf28841df1986573e67 193 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 2 84 4.4E-7 T 23-04-2016 IPR000014 PAS domain DC74_RS38780 2d9d4a7a932f7bf28841df1986573e67 193 Pfam PF08448 PAS fold 3 77 2.9E-10 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS38780 2d9d4a7a932f7bf28841df1986573e67 193 Gene3D G3DSA:3.30.450.20 3 93 1.1E-9 T 23-04-2016 DC74_RS38780 2d9d4a7a932f7bf28841df1986573e67 193 Pfam PF00196 Bacterial regulatory proteins, luxR family 118 171 1.1E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38780 2d9d4a7a932f7bf28841df1986573e67 193 SUPERFAMILY SSF46894 112 179 6.12E-12 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS38780 2d9d4a7a932f7bf28841df1986573e67 193 SUPERFAMILY SSF55785 3 98 1.23E-10 T 23-04-2016 IPR000014 PAS domain DC74_RS38780 2d9d4a7a932f7bf28841df1986573e67 193 SMART SM00421 115 172 2.2E-6 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38780 2d9d4a7a932f7bf28841df1986573e67 193 Gene3D G3DSA:1.10.10.10 116 177 1.3E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS40560 d60e254215b2748d04ce58d11e86eaba 68 Gene3D G3DSA:3.60.21.10 18 65 5.0E-5 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS40560 d60e254215b2748d04ce58d11e86eaba 68 SUPERFAMILY SSF56300 17 62 1.03E-6 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS11525 86f7eb0c2ba4db57caeb1415742ca177 199 Gene3D G3DSA:3.40.50.300 10 199 1.1E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11525 86f7eb0c2ba4db57caeb1415742ca177 199 PIRSF PIRSF015617 1 199 5.1E-65 T 23-04-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 DC74_RS11525 86f7eb0c2ba4db57caeb1415742ca177 199 SUPERFAMILY SSF52540 12 199 2.0E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11525 86f7eb0c2ba4db57caeb1415742ca177 199 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 19 199 5.1E-71 T 23-04-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 DC74_RS11525 86f7eb0c2ba4db57caeb1415742ca177 199 PANTHER PTHR30069 7 199 3.1E-53 T 23-04-2016 DC74_RS11525 86f7eb0c2ba4db57caeb1415742ca177 199 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 22 199 1.2E-59 T 23-04-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 DC74_RS11950 60a441a8c7a26a9d799105d4e8c0dac4 180 SUPERFAMILY SSF160379 1 179 3.92E-47 T 23-04-2016 DC74_RS11950 60a441a8c7a26a9d799105d4e8c0dac4 180 Pfam PF08002 Protein of unknown function (DUF1697) 1 138 2.7E-36 T 23-04-2016 IPR012545 Protein of unknown function DUF1697 DC74_RS11950 60a441a8c7a26a9d799105d4e8c0dac4 180 PANTHER PTHR36439 1 180 6.1E-35 T 23-04-2016 DC74_RS11950 60a441a8c7a26a9d799105d4e8c0dac4 180 Gene3D G3DSA:3.30.70.1280 1 88 5.8E-21 T 23-04-2016 DC74_RS11950 60a441a8c7a26a9d799105d4e8c0dac4 180 PIRSF PIRSF008502 1 180 2.5E-45 T 23-04-2016 IPR012545 Protein of unknown function DUF1697 DC74_RS11950 60a441a8c7a26a9d799105d4e8c0dac4 180 PANTHER PTHR36439:SF1 1 180 6.1E-35 T 23-04-2016 DC74_RS05765 f541e11c64677e225299c95474fb713a 136 Pfam PF01740 STAS domain 22 101 5.6E-7 T 23-04-2016 IPR002645 STAS domain DC74_RS05765 f541e11c64677e225299c95474fb713a 136 Gene3D G3DSA:3.30.750.24 13 115 9.5E-14 T 23-04-2016 IPR002645 STAS domain DC74_RS05765 f541e11c64677e225299c95474fb713a 136 PANTHER PTHR33745 9 130 1.5E-36 T 23-04-2016 DC74_RS05765 f541e11c64677e225299c95474fb713a 136 SUPERFAMILY SSF52091 9 118 1.57E-17 T 23-04-2016 IPR002645 STAS domain DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 33 477 7.3E-144 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 Gene3D G3DSA:1.20.210.10 14 543 1.1E-188 T 23-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 SUPERFAMILY SSF81442 23 532 4.45E-170 T 23-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PANTHER PTHR10422:SF6 10 545 4.1E-282 T 23-04-2016 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 24 49 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 298 313 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 141 153 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 231 252 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 202 221 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 320 341 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 98 122 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 355 373 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 173 191 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 433 454 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 402 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 71 94 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PRINTS PR01165 Cytochrome c oxidase subunit I signature 252 273 8.9E-97 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 PANTHER PTHR10422 10 545 4.1E-282 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 254 308 - T 23-04-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS10970 7440250f4d72cf625b2317ab04608ff9 559 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 25 529 6.3E-207 T 23-04-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS16640 25bce0c015c0a4c5ebcef7c22a5e46d0 394 SMART SM00862 310 380 1.0E-13 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS16640 25bce0c015c0a4c5ebcef7c22a5e46d0 394 Gene3D G3DSA:3.40.50.10090 153 288 1.1E-36 T 23-04-2016 DC74_RS16640 25bce0c015c0a4c5ebcef7c22a5e46d0 394 Gene3D G3DSA:3.40.50.10090 21 150 1.0E-33 T 23-04-2016 DC74_RS16640 25bce0c015c0a4c5ebcef7c22a5e46d0 394 SUPERFAMILY SSF46894 294 380 3.12E-13 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS16640 25bce0c015c0a4c5ebcef7c22a5e46d0 394 Pfam PF00486 Transcriptional regulatory protein, C terminal 317 380 5.0E-13 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS16640 25bce0c015c0a4c5ebcef7c22a5e46d0 394 PANTHER PTHR40082 15 296 3.4E-28 T 23-04-2016 DC74_RS16640 25bce0c015c0a4c5ebcef7c22a5e46d0 394 Pfam PF02602 Uroporphyrinogen-III synthase HemD 37 279 4.3E-43 T 23-04-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS16640 25bce0c015c0a4c5ebcef7c22a5e46d0 394 Gene3D G3DSA:1.10.10.10 298 381 7.0E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16640 25bce0c015c0a4c5ebcef7c22a5e46d0 394 SUPERFAMILY SSF69618 25 286 1.01E-58 T 23-04-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS11165 8b00c2dfcf3d191b8d690befdea9b84a 515 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 93 112 6.3E-9 T 23-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 DC74_RS11165 8b00c2dfcf3d191b8d690befdea9b84a 515 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 368 383 6.3E-9 T 23-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 DC74_RS11165 8b00c2dfcf3d191b8d690befdea9b84a 515 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 411 430 6.3E-9 T 23-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 DC74_RS11165 8b00c2dfcf3d191b8d690befdea9b84a 515 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 133 152 6.3E-9 T 23-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 DC74_RS11165 8b00c2dfcf3d191b8d690befdea9b84a 515 PANTHER PTHR11999:SF87 24 495 2.3E-240 T 23-04-2016 DC74_RS11165 8b00c2dfcf3d191b8d690befdea9b84a 515 Gene3D G3DSA:3.40.640.10 103 382 8.9E-95 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS11165 8b00c2dfcf3d191b8d690befdea9b84a 515 PANTHER PTHR11999 24 495 2.3E-240 T 23-04-2016 DC74_RS11165 8b00c2dfcf3d191b8d690befdea9b84a 515 Gene3D G3DSA:1.20.1650.10 9 92 1.1E-23 T 23-04-2016 DC74_RS11165 8b00c2dfcf3d191b8d690befdea9b84a 515 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 91 429 7.3E-66 T 23-04-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 DC74_RS11165 8b00c2dfcf3d191b8d690befdea9b84a 515 SUPERFAMILY SSF53383 46 498 1.95E-118 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS11165 8b00c2dfcf3d191b8d690befdea9b84a 515 Gene3D G3DSA:3.90.1150.10 383 497 1.6E-42 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS24395 c52122605bdd5add3c9c4668a8460c76 375 Pfam PF07728 AAA domain (dynein-related subfamily) 93 231 1.2E-35 T 23-04-2016 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 DC74_RS24395 c52122605bdd5add3c9c4668a8460c76 375 SUPERFAMILY SSF52540 70 346 1.74E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24395 c52122605bdd5add3c9c4668a8460c76 375 PANTHER PTHR22908 57 311 1.3E-118 T 23-04-2016 DC74_RS24395 c52122605bdd5add3c9c4668a8460c76 375 PANTHER PTHR22908:SF67 57 311 1.3E-118 T 23-04-2016 DC74_RS24395 c52122605bdd5add3c9c4668a8460c76 375 Gene3D G3DSA:3.40.50.300 75 248 7.5E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22710 153df08dd5191794e6b31e120599dc43 582 PRINTS PR01217 Proline rich extensin signature 535 560 5.4E-9 T 23-04-2016 DC74_RS22710 153df08dd5191794e6b31e120599dc43 582 PRINTS PR01217 Proline rich extensin signature 515 532 5.4E-9 T 23-04-2016 DC74_RS22710 153df08dd5191794e6b31e120599dc43 582 PRINTS PR01217 Proline rich extensin signature 573 582 5.4E-9 T 23-04-2016 DC74_RS22710 153df08dd5191794e6b31e120599dc43 582 PRINTS PR01217 Proline rich extensin signature 387 403 5.4E-9 T 23-04-2016 DC74_RS22710 153df08dd5191794e6b31e120599dc43 582 PRINTS PR01217 Proline rich extensin signature 414 426 5.4E-9 T 23-04-2016 DC74_RS22710 153df08dd5191794e6b31e120599dc43 582 Gene3D G3DSA:2.60.40.360 436 499 1.5E-4 T 23-04-2016 IPR008962 PapD-like DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 Gene3D G3DSA:2.60.200.20 133 222 2.5E-22 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 Gene3D G3DSA:2.60.200.20 7 94 2.2E-19 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 Pfam PF00498 FHA domain 142 214 1.9E-15 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 Pfam PF01061 ABC-2 type transporter 526 732 5.6E-19 T 23-04-2016 IPR013525 ABC-2 type transporter GO:0016020 DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 Pfam PF00005 ABC transporter 255 402 3.3E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 26 94 1.7E-15 T 23-04-2016 IPR032030 YscD, cytoplasmic domain DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 SUPERFAMILY SSF49879 108 237 1.28E-25 T 23-04-2016 IPR008984 SMAD/FHA domain GO:0005515 DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 PANTHER PTHR19241:SF189 231 788 2.5E-95 T 23-04-2016 DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 ProSitePatterns PS00211 ABC transporters family signature. 374 388 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 Gene3D G3DSA:3.40.50.300 230 461 3.1E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 SMART SM00240 29 79 1.7E-10 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 SMART SM00240 141 200 2.2E-15 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 PANTHER PTHR19241 231 788 2.5E-95 T 23-04-2016 DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 SMART SM00382 264 457 1.7E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 SUPERFAMILY SSF49879 11 95 1.87E-20 T 23-04-2016 IPR008984 SMAD/FHA domain GO:0005515 DC74_RS31010 defb84756cd6806d2ce66e1affd1f1d5 789 SUPERFAMILY SSF52540 229 466 5.53E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 SUPERFAMILY SSF55681 5 369 1.63E-120 T 23-04-2016 DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 157 333 2.6E-10 T 23-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 234 7.9E-82 T 23-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 PANTHER PTHR10745 7 453 5.9E-210 T 23-04-2016 IPR027031 Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 KEGG: 00970+6.1.1.14 DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 Gene3D G3DSA:3.30.930.10 7 361 1.1E-144 T 23-04-2016 DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 Pfam PF03129 Anticodon binding domain 366 453 9.3E-22 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 403 422 1.9E-50 T 23-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 190 207 1.9E-50 T 23-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 137 149 1.9E-50 T 23-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 1.9E-50 T 23-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 207 217 1.9E-50 T 23-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 158 175 1.9E-50 T 23-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 317 329 1.9E-50 T 23-04-2016 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 SUPERFAMILY SSF52954 353 456 1.09E-32 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 Gene3D G3DSA:3.40.50.800 362 456 2.8E-39 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS14840 e1070f0081fed6320a30a360ff2b2876 460 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 458 49.788 T 23-04-2016 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 DC74_RS17575 5b6fb12f80c0168612f599eb435426ae 228 Gene3D G3DSA:1.10.10.10 124 217 2.3E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17575 5b6fb12f80c0168612f599eb435426ae 228 Gene3D G3DSA:3.40.50.2300 2 123 4.3E-13 T 23-04-2016 DC74_RS17575 5b6fb12f80c0168612f599eb435426ae 228 SMART SM00421 153 210 9.0E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS17575 5b6fb12f80c0168612f599eb435426ae 228 PANTHER PTHR26402 3 218 7.6E-67 T 23-04-2016 DC74_RS17575 5b6fb12f80c0168612f599eb435426ae 228 Pfam PF00072 Response regulator receiver domain 6 104 2.6E-6 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS17575 5b6fb12f80c0168612f599eb435426ae 228 SUPERFAMILY SSF46894 138 216 2.52E-17 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS17575 5b6fb12f80c0168612f599eb435426ae 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 3.0E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS17575 5b6fb12f80c0168612f599eb435426ae 228 PANTHER PTHR26402:SF547 3 218 7.6E-67 T 23-04-2016 DC74_RS17575 5b6fb12f80c0168612f599eb435426ae 228 SUPERFAMILY SSF52172 2 125 3.42E-12 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS17575 5b6fb12f80c0168612f599eb435426ae 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 4.6E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS17575 5b6fb12f80c0168612f599eb435426ae 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 4.6E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS17575 5b6fb12f80c0168612f599eb435426ae 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 4.6E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 Gene3D G3DSA:3.50.50.60 2 112 1.6E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 SUPERFAMILY SSF51905 2 190 1.89E-37 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 Pfam PF14759 Reductase C-terminal 327 398 1.8E-14 T 23-04-2016 IPR028202 Reductase, C-terminal DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 Gene3D G3DSA:3.30.390.30 327 397 1.3E-18 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 SUPERFAMILY SSF55424 319 396 2.33E-19 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 7.5E-21 T 23-04-2016 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 7.5E-21 T 23-04-2016 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 7.5E-21 T 23-04-2016 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 7.5E-21 T 23-04-2016 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 7.5E-21 T 23-04-2016 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 SUPERFAMILY SSF51905 152 316 6.16E-27 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 7.8E-15 T 23-04-2016 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 7.8E-15 T 23-04-2016 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 282 289 7.8E-15 T 23-04-2016 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 257 7.8E-15 T 23-04-2016 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 PANTHER PTHR22912 2 398 3.2E-86 T 23-04-2016 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 PANTHER PTHR22912:SF180 2 398 3.2E-86 T 23-04-2016 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 306 2.7E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06710 f84906d0434ad87e16bd83cf6e3f9a17 400 Gene3D G3DSA:3.50.50.60 113 314 4.4E-38 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14705 f45a57265ad29317bd97e8929be32f50 399 Gene3D G3DSA:3.30.70.360 185 300 1.9E-36 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS14705 f45a57265ad29317bd97e8929be32f50 399 SUPERFAMILY SSF55031 187 299 3.53E-28 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS14705 f45a57265ad29317bd97e8929be32f50 399 Pfam PF01546 Peptidase family M20/M25/M40 72 389 1.5E-30 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS14705 f45a57265ad29317bd97e8929be32f50 399 Gene3D G3DSA:3.40.630.10 301 396 1.1E-84 T 23-04-2016 DC74_RS14705 f45a57265ad29317bd97e8929be32f50 399 Gene3D G3DSA:3.40.630.10 4 181 1.1E-84 T 23-04-2016 DC74_RS14705 f45a57265ad29317bd97e8929be32f50 399 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 379 5.7E-86 T 23-04-2016 IPR017439 Amidohydrolase GO:0016787 DC74_RS14705 f45a57265ad29317bd97e8929be32f50 399 PANTHER PTHR11014:SF63 3 397 8.9E-120 T 23-04-2016 DC74_RS14705 f45a57265ad29317bd97e8929be32f50 399 Pfam PF07687 Peptidase dimerisation domain 190 268 8.5E-10 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS14705 f45a57265ad29317bd97e8929be32f50 399 SUPERFAMILY SSF53187 301 394 1.79E-68 T 23-04-2016 DC74_RS14705 f45a57265ad29317bd97e8929be32f50 399 SUPERFAMILY SSF53187 5 200 1.79E-68 T 23-04-2016 DC74_RS14705 f45a57265ad29317bd97e8929be32f50 399 PANTHER PTHR11014 3 397 8.9E-120 T 23-04-2016 DC74_RS14705 f45a57265ad29317bd97e8929be32f50 399 PIRSF PIRSF005962 2 397 7.0E-102 T 23-04-2016 IPR017439 Amidohydrolase GO:0016787 DC74_RS37790 6db73993861866d97ee5bf6ab5bd7adc 496 PANTHER PTHR34704 13 361 1.1E-33 T 23-04-2016 DC74_RS37790 6db73993861866d97ee5bf6ab5bd7adc 496 SUPERFAMILY SSF52540 9 208 3.72E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37790 6db73993861866d97ee5bf6ab5bd7adc 496 Gene3D G3DSA:3.40.50.300 11 184 1.2E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37790 6db73993861866d97ee5bf6ab5bd7adc 496 SUPERFAMILY SSF46785 271 335 4.55E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37790 6db73993861866d97ee5bf6ab5bd7adc 496 Gene3D G3DSA:1.10.10.10 271 328 6.9E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 SUPERFAMILY SSF49503 206 251 2.17E-28 T 23-04-2016 IPR008972 Cupredoxin DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 SUPERFAMILY SSF49503 284 385 2.17E-28 T 23-04-2016 IPR008972 Cupredoxin DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 Gene3D G3DSA:2.60.40.420 208 399 2.1E-42 T 23-04-2016 IPR008972 Cupredoxin DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 Pfam PF00394 Multicopper oxidase 282 386 1.6E-23 T 23-04-2016 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 SUPERFAMILY SSF49503 417 532 1.4E-34 T 23-04-2016 IPR008972 Cupredoxin DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 Pfam PF07731 Multicopper oxidase 424 533 1.3E-27 T 23-04-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 PANTHER PTHR11709 79 243 4.0E-97 T 23-04-2016 DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 PANTHER PTHR11709 285 533 4.0E-97 T 23-04-2016 DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 SUPERFAMILY SSF49503 85 222 5.52E-33 T 23-04-2016 IPR008972 Cupredoxin DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 Gene3D G3DSA:2.60.40.420 81 206 4.7E-33 T 23-04-2016 IPR008972 Cupredoxin DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 Gene3D G3DSA:2.60.40.420 414 536 2.4E-43 T 23-04-2016 IPR008972 Cupredoxin DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 Pfam PF07732 Multicopper oxidase 104 204 1.1E-29 T 23-04-2016 IPR011707 Multicopper oxidase, type 3 GO:0005507 DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 PANTHER PTHR11709:SF33 79 243 4.0E-97 T 23-04-2016 DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 PANTHER PTHR11709:SF33 285 533 4.0E-97 T 23-04-2016 DC74_RS05305 a8d105bbf569a1f796a92426a872eb19 539 ProSitePatterns PS00080 Multicopper oxidases signature 2. 518 529 - T 23-04-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 DC74_RS11840 08d789686de6959c42566ec79f6eb6a8 353 Gene3D G3DSA:3.40.50.10680 101 344 1.0E-43 T 23-04-2016 DC74_RS11840 08d789686de6959c42566ec79f6eb6a8 353 Hamap MF_00973 Gluconeogenesis factor. 24 345 32.337 T 23-04-2016 IPR010119 Gluconeogenesis factor DC74_RS11840 08d789686de6959c42566ec79f6eb6a8 353 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 28 341 9.2E-85 T 23-04-2016 IPR010119 Gluconeogenesis factor DC74_RS11840 08d789686de6959c42566ec79f6eb6a8 353 PANTHER PTHR30135:SF3 19 353 2.4E-120 T 23-04-2016 DC74_RS11840 08d789686de6959c42566ec79f6eb6a8 353 SUPERFAMILY SSF142338 26 338 1.83E-81 T 23-04-2016 DC74_RS11840 08d789686de6959c42566ec79f6eb6a8 353 Pfam PF01933 Uncharacterised protein family UPF0052 28 291 3.9E-74 T 23-04-2016 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 DC74_RS11840 08d789686de6959c42566ec79f6eb6a8 353 PANTHER PTHR30135 19 353 2.4E-120 T 23-04-2016 DC74_RS37195 4514dcdb73e82234b2d90a79bcf60b7a 243 Pfam PF00106 short chain dehydrogenase 4 201 2.9E-33 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37195 4514dcdb73e82234b2d90a79bcf60b7a 243 Gene3D G3DSA:3.40.50.720 1 236 3.8E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37195 4514dcdb73e82234b2d90a79bcf60b7a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.8E-16 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37195 4514dcdb73e82234b2d90a79bcf60b7a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 2.8E-16 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37195 4514dcdb73e82234b2d90a79bcf60b7a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.8E-16 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37195 4514dcdb73e82234b2d90a79bcf60b7a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.8E-16 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37195 4514dcdb73e82234b2d90a79bcf60b7a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 2.8E-16 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37195 4514dcdb73e82234b2d90a79bcf60b7a 243 PANTHER PTHR24322 165 196 4.2E-33 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37195 4514dcdb73e82234b2d90a79bcf60b7a 243 PANTHER PTHR24322 8 141 4.2E-33 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37195 4514dcdb73e82234b2d90a79bcf60b7a 243 SUPERFAMILY SSF51735 4 235 1.11E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS28760 2c6fd2ae9923b8156ec4a0532343d662 508 PANTHER PTHR33392:SF1 162 506 9.1E-94 T 23-04-2016 DC74_RS28760 2c6fd2ae9923b8156ec4a0532343d662 508 PANTHER PTHR33392:SF1 6 143 9.1E-94 T 23-04-2016 DC74_RS28760 2c6fd2ae9923b8156ec4a0532343d662 508 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 94 268 1.7E-39 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS28760 2c6fd2ae9923b8156ec4a0532343d662 508 PANTHER PTHR33392 162 506 9.1E-94 T 23-04-2016 DC74_RS28760 2c6fd2ae9923b8156ec4a0532343d662 508 PANTHER PTHR33392 6 143 9.1E-94 T 23-04-2016 DC74_RS28760 2c6fd2ae9923b8156ec4a0532343d662 508 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 374 458 2.9E-12 T 23-04-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain DC74_RS28760 2c6fd2ae9923b8156ec4a0532343d662 508 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 94 268 2.1E-28 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 Gene3D G3DSA:1.10.10.10 12 84 6.1E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 80 6.6E-15 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 SMART SM00866 101 241 4.9E-17 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 PANTHER PTHR11751:SF333 222 245 1.4E-14 T 23-04-2016 DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 SUPERFAMILY SSF46785 12 89 1.14E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 Gene3D G3DSA:3.40.1410.10 92 245 7.0E-33 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 PANTHER PTHR11751 11 82 1.4E-14 T 23-04-2016 DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 SMART SM00345 21 80 6.5E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 Pfam PF07702 UTRA domain 105 240 2.7E-24 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 PANTHER PTHR11751:SF333 11 82 1.4E-14 T 23-04-2016 DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 PANTHER PTHR11751 222 245 1.4E-14 T 23-04-2016 DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 SUPERFAMILY SSF64288 68 247 5.65E-33 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 3.7E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10735 7ff094dc6b08b71c76972753338564fa 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 3.7E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS27200 61c62fb94291622cb4d9cbf0ec145cdf 442 Gene3D G3DSA:1.20.1250.20 35 209 6.7E-5 T 23-04-2016 DC74_RS27200 61c62fb94291622cb4d9cbf0ec145cdf 442 SUPERFAMILY SSF103473 38 414 9.42E-22 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS27200 61c62fb94291622cb4d9cbf0ec145cdf 442 PANTHER PTHR23513 18 442 8.3E-29 T 23-04-2016 DC74_RS27200 61c62fb94291622cb4d9cbf0ec145cdf 442 Pfam PF05977 Transmembrane secretion effector 33 407 1.0E-6 T 23-04-2016 IPR010290 Transmembrane secretion effector DC74_RS32000 583665286499baf5c74de10e8a4016bd 357 Gene3D G3DSA:3.40.50.1820 43 342 1.1E-26 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS32000 583665286499baf5c74de10e8a4016bd 357 Pfam PF00561 alpha/beta hydrolase fold 71 334 3.9E-7 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS32000 583665286499baf5c74de10e8a4016bd 357 PANTHER PTHR10992 243 343 6.9E-13 T 23-04-2016 DC74_RS32000 583665286499baf5c74de10e8a4016bd 357 PANTHER PTHR10992 90 222 6.9E-13 T 23-04-2016 DC74_RS32000 583665286499baf5c74de10e8a4016bd 357 SUPERFAMILY SSF53474 46 343 1.52E-27 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS18680 1fe2fa823880a373493cfd5f0e9d7985 107 Gene3D G3DSA:2.30.30.30 1 95 1.1E-25 T 23-04-2016 IPR014722 Ribosomal protein L2 domain 2 DC74_RS18680 1fe2fa823880a373493cfd5f0e9d7985 107 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 101 21.249 T 23-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18680 1fe2fa823880a373493cfd5f0e9d7985 107 Pfam PF00467 KOW motif 5 36 1.1E-7 T 23-04-2016 IPR005824 KOW DC74_RS18680 1fe2fa823880a373493cfd5f0e9d7985 107 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 107 1.7E-35 T 23-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18680 1fe2fa823880a373493cfd5f0e9d7985 107 SMART SM00739 2 29 1.0E-5 T 23-04-2016 IPR005824 KOW DC74_RS18680 1fe2fa823880a373493cfd5f0e9d7985 107 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 107 4.4E-23 T 23-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18680 1fe2fa823880a373493cfd5f0e9d7985 107 PANTHER PTHR12903 1 107 6.0E-43 T 23-04-2016 DC74_RS18680 1fe2fa823880a373493cfd5f0e9d7985 107 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 23-04-2016 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18680 1fe2fa823880a373493cfd5f0e9d7985 107 SUPERFAMILY SSF50104 1 105 4.51E-30 T 23-04-2016 IPR008991 Translation protein SH3-like domain DC74_RS36680 d8e6d4576e4d6c1120df068247b1dd8d 396 PANTHER PTHR21021 110 396 1.7E-41 T 23-04-2016 DC74_RS36680 d8e6d4576e4d6c1120df068247b1dd8d 396 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 212 393 5.0E-43 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS36680 d8e6d4576e4d6c1120df068247b1dd8d 396 SUPERFAMILY SSF81606 198 394 1.46E-9 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS36680 d8e6d4576e4d6c1120df068247b1dd8d 396 PANTHER PTHR21021:SF19 110 396 1.7E-41 T 23-04-2016 DC74_RS36680 d8e6d4576e4d6c1120df068247b1dd8d 396 Gene3D G3DSA:3.30.450.40 18 159 4.1E-13 T 23-04-2016 IPR029016 GAF domain-like DC74_RS36680 d8e6d4576e4d6c1120df068247b1dd8d 396 SMART SM00331 181 393 7.3E-33 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS36680 d8e6d4576e4d6c1120df068247b1dd8d 396 SUPERFAMILY SSF55781 35 165 9.81E-8 T 23-04-2016 IPR029016 GAF domain-like DC74_RS23140 63a693c4f93e972f776546c25ffb8e0b 347 PANTHER PTHR30472:SF32 2 344 9.4E-140 T 23-04-2016 DC74_RS23140 63a693c4f93e972f776546c25ffb8e0b 347 PANTHER PTHR30472 2 344 9.4E-140 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS23140 63a693c4f93e972f776546c25ffb8e0b 347 SUPERFAMILY SSF81345 5 339 8.76E-77 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS23140 63a693c4f93e972f776546c25ffb8e0b 347 Pfam PF01032 FecCD transport family 19 338 2.6E-87 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS23140 63a693c4f93e972f776546c25ffb8e0b 347 Gene3D G3DSA:1.10.3470.10 5 340 2.0E-98 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS24905 9fca71f9cf1084cc73693e3932b417b7 317 Pfam PF03102 NeuB family 41 277 2.8E-82 T 23-04-2016 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 DC74_RS24905 9fca71f9cf1084cc73693e3932b417b7 317 Gene3D G3DSA:3.20.20.70 10 277 7.3E-101 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS24905 9fca71f9cf1084cc73693e3932b417b7 317 PANTHER PTHR23416:SF1 8 302 1.2E-120 T 23-04-2016 DC74_RS24905 9fca71f9cf1084cc73693e3932b417b7 317 PANTHER PTHR23416 8 302 1.2E-120 T 23-04-2016 DC74_RS24905 9fca71f9cf1084cc73693e3932b417b7 317 SUPERFAMILY SSF51569 10 290 1.04E-86 T 23-04-2016 DC74_RS29555 599cf2f9807a148736da6aaff45e8dbf 582 Gene3D G3DSA:1.10.540.10 38 125 3.9E-10 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS29555 599cf2f9807a148736da6aaff45e8dbf 582 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 386 1.3E-18 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS29555 599cf2f9807a148736da6aaff45e8dbf 582 SUPERFAMILY SSF47203 234 387 7.89E-24 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS29555 599cf2f9807a148736da6aaff45e8dbf 582 Gene3D G3DSA:2.40.110.10 127 224 9.3E-20 T 23-04-2016 DC74_RS29555 599cf2f9807a148736da6aaff45e8dbf 582 Gene3D G3DSA:1.20.140.10 225 387 5.7E-28 T 23-04-2016 DC74_RS29555 599cf2f9807a148736da6aaff45e8dbf 582 PANTHER PTHR10909 36 387 1.4E-52 T 23-04-2016 DC74_RS29555 599cf2f9807a148736da6aaff45e8dbf 582 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 124 2.5E-6 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS29555 599cf2f9807a148736da6aaff45e8dbf 582 SUPERFAMILY SSF56645 35 234 9.42E-39 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS29555 599cf2f9807a148736da6aaff45e8dbf 582 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 221 2.8E-11 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS22905 6ade6148655a2fb5f3106c82209a4f80 235 SMART SM00014 67 178 3.5E-11 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS22905 6ade6148655a2fb5f3106c82209a4f80 235 PANTHER PTHR14969 10 182 2.1E-40 T 23-04-2016 DC74_RS22905 6ade6148655a2fb5f3106c82209a4f80 235 Gene3D G3DSA:1.20.144.10 17 178 4.4E-27 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS22905 6ade6148655a2fb5f3106c82209a4f80 235 SUPERFAMILY SSF48317 10 183 1.44E-32 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS22905 6ade6148655a2fb5f3106c82209a4f80 235 Pfam PF01569 PAP2 superfamily 74 182 4.1E-15 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS22905 6ade6148655a2fb5f3106c82209a4f80 235 PANTHER PTHR14969:SF20 10 182 2.1E-40 T 23-04-2016 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 Pfam PF00128 Alpha amylase, catalytic domain 232 321 2.6E-6 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 SUPERFAMILY SSF81296 164 182 1.36E-37 T 23-04-2016 IPR014756 Immunoglobulin E-set DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 SUPERFAMILY SSF81296 23 135 1.36E-37 T 23-04-2016 IPR014756 Immunoglobulin E-set DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 SUPERFAMILY SSF51011 634 751 4.17E-17 T 23-04-2016 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 PANTHER PTHR10357:SF74 141 624 0.0 T 23-04-2016 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 Gene3D G3DSA:3.20.20.80 197 622 4.9E-123 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 28 119 4.8E-21 T 23-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 SMART SM00642 202 613 1.6E-7 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 24 750 9.2E-301 T 23-04-2016 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 UniPathway: UPA00165 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 SUPERFAMILY SSF51445 179 514 1.58E-131 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 SUPERFAMILY SSF51445 543 621 1.58E-131 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 PANTHER PTHR10357:SF74 6 118 0.0 T 23-04-2016 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 PANTHER PTHR10357:SF74 643 751 0.0 T 23-04-2016 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 Gene3D G3DSA:2.60.40.10 23 133 3.0E-49 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 Gene3D G3DSA:2.60.40.10 170 196 3.0E-49 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 PANTHER PTHR10357 141 624 0.0 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 PANTHER PTHR10357 6 118 0.0 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 PANTHER PTHR10357 643 751 0.0 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS27355 d5ef5a5253b149f417ec550f0885f835 754 Gene3D G3DSA:2.60.40.1180 634 751 2.2E-22 T 23-04-2016 IPR013780 Glycosyl hydrolase, all-beta DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 PANTHER PTHR24095 108 813 2.1E-170 T 23-04-2016 DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 SUPERFAMILY SSF56801 196 758 9.29E-149 T 23-04-2016 DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 Gene3D G3DSA:2.30.38.10 547 626 7.1E-22 T 23-04-2016 DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 PANTHER PTHR24095:SF137 108 813 2.1E-170 T 23-04-2016 DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 SMART SM00823 Phosphopantetheine attachment site 745 812 0.0099 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 Gene3D G3DSA:3.40.50.1820 820 936 2.3E-18 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 Gene3D G3DSA:3.40.50.1820 1006 1049 2.3E-18 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 Pfam PF00501 AMP-binding enzyme 233 636 5.8E-91 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 Pfam PF13193 AMP-binding enzyme C-terminal domain 644 717 2.8E-11 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 SUPERFAMILY SSF53474 774 1065 2.58E-33 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 Pfam PF00975 Thioesterase domain 832 933 2.8E-17 T 23-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 SUPERFAMILY SSF52777 27 201 2.11E-15 T 23-04-2016 DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 Pfam PF00550 Phosphopantetheine attachment site 747 808 3.0E-8 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 Gene3D G3DSA:1.10.1200.10 748 813 1.4E-20 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 ProSitePatterns PS00455 Putative AMP-binding domain signature. 378 389 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 Gene3D G3DSA:3.30.300.30 632 747 1.5E-35 T 23-04-2016 DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 254 660 6.8E-116 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 Gene3D G3DSA:3.40.50.980 385 535 1.8E-44 T 23-04-2016 DC74_RS38840 96db09bc09c4f94fd663d9686b9edc0d 1073 Gene3D G3DSA:3.40.50.980 226 384 1.6E-48 T 23-04-2016 DC74_RS37370 586170fe562cb4627f94a05cf77ac376 303 SUPERFAMILY SSF53167 10 276 6.4E-89 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS37370 586170fe562cb4627f94a05cf77ac376 303 PANTHER PTHR11904 1 299 2.3E-130 T 23-04-2016 IPR001369 PNP/MTAP phosphorylase DC74_RS37370 586170fe562cb4627f94a05cf77ac376 303 Pfam PF01048 Phosphorylase superfamily 12 252 5.5E-44 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS37370 586170fe562cb4627f94a05cf77ac376 303 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 10 272 44.181 T 23-04-2016 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 DC74_RS37370 586170fe562cb4627f94a05cf77ac376 303 PANTHER PTHR11904:SF1 1 299 2.3E-130 T 23-04-2016 DC74_RS37370 586170fe562cb4627f94a05cf77ac376 303 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 58 98 - T 23-04-2016 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 DC74_RS37370 586170fe562cb4627f94a05cf77ac376 303 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 12 250 5.4E-96 T 23-04-2016 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 DC74_RS37370 586170fe562cb4627f94a05cf77ac376 303 Gene3D G3DSA:3.40.50.1580 9 268 2.4E-92 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS02360 94708c727623fc652c81ecd6afd15561 239 SUPERFAMILY SSF53335 10 209 2.3E-33 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS02360 94708c727623fc652c81ecd6afd15561 239 Gene3D G3DSA:3.40.50.150 14 201 4.1E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS02360 94708c727623fc652c81ecd6afd15561 239 Pfam PF13649 Methyltransferase domain 50 148 4.8E-20 T 23-04-2016 DC74_RS02360 94708c727623fc652c81ecd6afd15561 239 PANTHER PTHR10108 48 154 2.8E-22 T 23-04-2016 DC74_RS37140 066043b4387e4cb969770270ced80356 589 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS37140 066043b4387e4cb969770270ced80356 589 Gene3D G3DSA:3.40.50.300 338 568 9.3E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37140 066043b4387e4cb969770270ced80356 589 SUPERFAMILY SSF52540 330 572 1.38E-85 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37140 066043b4387e4cb969770270ced80356 589 Pfam PF00664 ABC transporter transmembrane region 23 289 2.2E-40 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS37140 066043b4387e4cb969770270ced80356 589 PANTHER PTHR24221 7 572 6.2E-202 T 23-04-2016 DC74_RS37140 066043b4387e4cb969770270ced80356 589 Pfam PF00005 ABC transporter 357 503 2.2E-33 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS37140 066043b4387e4cb969770270ced80356 589 Gene3D G3DSA:1.20.1560.10 7 326 1.3E-76 T 23-04-2016 DC74_RS37140 066043b4387e4cb969770270ced80356 589 SUPERFAMILY SSF90123 8 326 1.16E-72 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS37140 066043b4387e4cb969770270ced80356 589 SMART SM00382 364 550 2.2E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS05980 0eda9903cd22da7d72bae04174a527a3 448 SUPERFAMILY SSF103473 243 447 1.13E-59 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05980 0eda9903cd22da7d72bae04174a527a3 448 SUPERFAMILY SSF103473 7 197 1.13E-59 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05980 0eda9903cd22da7d72bae04174a527a3 448 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS05980 0eda9903cd22da7d72bae04174a527a3 448 PANTHER PTHR23501 8 447 1.3E-107 T 23-04-2016 DC74_RS05980 0eda9903cd22da7d72bae04174a527a3 448 Gene3D G3DSA:1.20.1250.20 260 447 1.9E-19 T 23-04-2016 DC74_RS05980 0eda9903cd22da7d72bae04174a527a3 448 Gene3D G3DSA:1.20.1250.20 16 190 1.1E-27 T 23-04-2016 DC74_RS05980 0eda9903cd22da7d72bae04174a527a3 448 Pfam PF07690 Major Facilitator Superfamily 22 406 1.2E-46 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS15525 81387f935bc17e0a6be35b607cecf114 230 SUPERFAMILY SSF46785 7 78 2.93E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS15525 81387f935bc17e0a6be35b607cecf114 230 Pfam PF07729 FCD domain 97 214 1.9E-20 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS15525 81387f935bc17e0a6be35b607cecf114 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 6.8E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS15525 81387f935bc17e0a6be35b607cecf114 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 6.8E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS15525 81387f935bc17e0a6be35b607cecf114 230 SMART SM00895 95 219 1.0E-16 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS15525 81387f935bc17e0a6be35b607cecf114 230 Gene3D G3DSA:1.10.10.10 7 76 6.9E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS15525 81387f935bc17e0a6be35b607cecf114 230 PANTHER PTHR11751:SF342 8 111 5.0E-29 T 23-04-2016 DC74_RS15525 81387f935bc17e0a6be35b607cecf114 230 PANTHER PTHR11751 8 111 5.0E-29 T 23-04-2016 DC74_RS15525 81387f935bc17e0a6be35b607cecf114 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 1.4E-16 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS15525 81387f935bc17e0a6be35b607cecf114 230 SMART SM00345 15 74 1.0E-16 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS15525 81387f935bc17e0a6be35b607cecf114 230 SUPERFAMILY SSF48008 92 221 1.12E-22 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS15525 81387f935bc17e0a6be35b607cecf114 230 Gene3D G3DSA:1.20.120.530 90 217 2.5E-23 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS22465 0b6ef37d8a4432876e316abdb7881117 162 Pfam PF13474 SnoaL-like domain 10 135 1.7E-30 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS22465 0b6ef37d8a4432876e316abdb7881117 162 Gene3D G3DSA:3.10.450.50 5 145 4.7E-47 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS22465 0b6ef37d8a4432876e316abdb7881117 162 PANTHER PTHR34957 3 146 7.5E-46 T 23-04-2016 DC74_RS22465 0b6ef37d8a4432876e316abdb7881117 162 SUPERFAMILY SSF54427 5 135 3.21E-37 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS07470 7b828e21308ef006730d6934abe1f0a3 353 Gene3D G3DSA:1.10.10.10 18 107 4.8E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07470 7b828e21308ef006730d6934abe1f0a3 353 Pfam PF00891 O-methyltransferase 119 330 1.0E-37 T 23-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 DC74_RS07470 7b828e21308ef006730d6934abe1f0a3 353 PANTHER PTHR11746:SF63 19 349 9.5E-76 T 23-04-2016 DC74_RS07470 7b828e21308ef006730d6934abe1f0a3 353 PANTHER PTHR11746 19 349 9.5E-76 T 23-04-2016 DC74_RS07470 7b828e21308ef006730d6934abe1f0a3 353 Gene3D G3DSA:3.40.50.150 108 348 2.4E-56 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS07470 7b828e21308ef006730d6934abe1f0a3 353 SUPERFAMILY SSF46785 21 104 3.99E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07470 7b828e21308ef006730d6934abe1f0a3 353 PIRSF PIRSF005739 5 347 4.7E-43 T 23-04-2016 IPR016461 O-methyltransferase COMT-type GO:0008168 DC74_RS07470 7b828e21308ef006730d6934abe1f0a3 353 SUPERFAMILY SSF53335 105 347 7.91E-45 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS34355 f2b985c4aef47160156c81c588f908aa 367 PANTHER PTHR22893 1 366 4.2E-162 T 23-04-2016 DC74_RS34355 f2b985c4aef47160156c81c588f908aa 367 SUPERFAMILY SSF51395 2 355 3.1E-114 T 23-04-2016 DC74_RS34355 f2b985c4aef47160156c81c588f908aa 367 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 352 3.1E-73 T 23-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 DC74_RS34355 f2b985c4aef47160156c81c588f908aa 367 Gene3D G3DSA:3.20.20.70 2 361 4.2E-131 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS34355 f2b985c4aef47160156c81c588f908aa 367 PANTHER PTHR22893:SF7 1 366 4.2E-162 T 23-04-2016 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 PIRSF PIRSF002560 1 157 1.8E-65 T 23-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 23-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 Pfam PF00210 Ferritin-like domain 8 143 6.1E-32 T 23-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 PANTHER PTHR30295 1 156 2.5E-44 T 23-04-2016 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 Gene3D G3DSA:1.20.1260.10 1 156 2.0E-53 T 23-04-2016 IPR012347 Ferritin-related DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 SUPERFAMILY SSF47240 1 155 5.23E-45 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 PANTHER PTHR30295:SF0 1 156 2.5E-44 T 23-04-2016 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 6.0E-65 T 23-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 PRINTS PR00601 Bacterioferritin signature 23 43 9.0E-57 T 23-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 PRINTS PR00601 Bacterioferritin signature 86 106 9.0E-57 T 23-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 PRINTS PR00601 Bacterioferritin signature 44 64 9.0E-57 T 23-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 PRINTS PR00601 Bacterioferritin signature 3 22 9.0E-57 T 23-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 PRINTS PR00601 Bacterioferritin signature 128 149 9.0E-57 T 23-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 PRINTS PR00601 Bacterioferritin signature 65 85 9.0E-57 T 23-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 DC74_RS12705 e76f1f37f2840c7059e3f0613a71f336 158 PRINTS PR00601 Bacterioferritin signature 107 127 9.0E-57 T 23-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 DC74_RS36925 f11d8b1a9519f3636bc816e18ba74254 584 Pfam PF00005 ABC transporter 365 513 1.5E-20 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS36925 f11d8b1a9519f3636bc816e18ba74254 584 PANTHER PTHR24221:SF161 11 580 7.8E-114 T 23-04-2016 DC74_RS36925 f11d8b1a9519f3636bc816e18ba74254 584 Gene3D G3DSA:3.40.50.300 350 573 8.2E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36925 f11d8b1a9519f3636bc816e18ba74254 584 SMART SM00382 374 566 1.9E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS36925 f11d8b1a9519f3636bc816e18ba74254 584 SUPERFAMILY SSF90123 39 334 2.62E-40 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS36925 f11d8b1a9519f3636bc816e18ba74254 584 SUPERFAMILY SSF52540 347 572 2.33E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36925 f11d8b1a9519f3636bc816e18ba74254 584 PANTHER PTHR24221 11 580 7.8E-114 T 23-04-2016 DC74_RS36925 f11d8b1a9519f3636bc816e18ba74254 584 Gene3D G3DSA:1.20.1560.10 39 334 9.6E-38 T 23-04-2016 DC74_RS36925 f11d8b1a9519f3636bc816e18ba74254 584 Pfam PF00664 ABC transporter transmembrane region 41 300 3.4E-21 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS22560 44899a9c5d589fd5d82adc7b74f4aa13 400 PANTHER PTHR21299:SF1 19 241 1.1E-107 T 23-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 DC74_RS22560 44899a9c5d589fd5d82adc7b74f4aa13 400 PANTHER PTHR21299:SF1 287 358 1.1E-107 T 23-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 DC74_RS22560 44899a9c5d589fd5d82adc7b74f4aa13 400 SUPERFAMILY SSF52374 22 237 2.06E-81 T 23-04-2016 DC74_RS22560 44899a9c5d589fd5d82adc7b74f4aa13 400 Gene3D G3DSA:3.30.1300.10 287 346 1.8E-30 T 23-04-2016 DC74_RS22560 44899a9c5d589fd5d82adc7b74f4aa13 400 Gene3D G3DSA:3.30.1300.10 193 237 1.8E-30 T 23-04-2016 DC74_RS22560 44899a9c5d589fd5d82adc7b74f4aa13 400 PANTHER PTHR21299 19 241 1.1E-107 T 23-04-2016 DC74_RS22560 44899a9c5d589fd5d82adc7b74f4aa13 400 PANTHER PTHR21299 287 358 1.1E-107 T 23-04-2016 DC74_RS22560 44899a9c5d589fd5d82adc7b74f4aa13 400 Pfam PF02569 Pantoate-beta-alanine ligase 22 342 1.1E-85 T 23-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 DC74_RS22560 44899a9c5d589fd5d82adc7b74f4aa13 400 Hamap MF_00158 Pantothenate synthetase [panC]. 20 344 37.954 T 23-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 DC74_RS22560 44899a9c5d589fd5d82adc7b74f4aa13 400 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 34 239 1.9E-69 T 23-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 DC74_RS22560 44899a9c5d589fd5d82adc7b74f4aa13 400 SUPERFAMILY SSF52374 291 345 5.81E-5 T 23-04-2016 DC74_RS22560 44899a9c5d589fd5d82adc7b74f4aa13 400 Gene3D G3DSA:3.40.50.620 23 191 7.1E-68 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS37315 3335a416de10ac16fc40abc641a8a480 162 Gene3D G3DSA:1.10.357.10 1 154 6.6E-16 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS37315 3335a416de10ac16fc40abc641a8a480 162 SUPERFAMILY SSF48498 42 155 1.09E-8 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PANTHER PTHR24322 11 144 8.8E-53 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PANTHER PTHR24322 160 191 8.8E-53 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PANTHER PTHR24322:SF390 11 144 8.8E-53 T 23-04-2016 DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PANTHER PTHR24322:SF390 160 191 8.8E-53 T 23-04-2016 DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 SUPERFAMILY SSF51735 6 253 6.25E-73 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.4E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.4E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.4E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.4E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.4E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.4E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 2.3E-53 T 23-04-2016 DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 Gene3D G3DSA:3.40.50.720 1 253 2.5E-78 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.0E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.0E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02070 a99e982115198e343f0179e19eed9df1 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.0E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07695 67a952c0669fde68fd788e05263ec27b 212 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 6 198 38.084 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS07695 67a952c0669fde68fd788e05263ec27b 212 Pfam PF00574 Clp protease 25 197 1.8E-72 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA DC74_RS07695 67a952c0669fde68fd788e05263ec27b 212 SUPERFAMILY SSF52096 26 198 1.25E-62 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS07695 67a952c0669fde68fd788e05263ec27b 212 Gene3D G3DSA:3.90.226.10 25 197 4.6E-72 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS07695 67a952c0669fde68fd788e05263ec27b 212 PANTHER PTHR10381:SF22 28 197 3.0E-98 T 23-04-2016 DC74_RS07695 67a952c0669fde68fd788e05263ec27b 212 PRINTS PR00127 Clp protease catalytic subunit P signature 64 84 2.2E-42 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS07695 67a952c0669fde68fd788e05263ec27b 212 PRINTS PR00127 Clp protease catalytic subunit P signature 95 112 2.2E-42 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS07695 67a952c0669fde68fd788e05263ec27b 212 PRINTS PR00127 Clp protease catalytic subunit P signature 24 39 2.2E-42 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS07695 67a952c0669fde68fd788e05263ec27b 212 PRINTS PR00127 Clp protease catalytic subunit P signature 116 135 2.2E-42 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS07695 67a952c0669fde68fd788e05263ec27b 212 PRINTS PR00127 Clp protease catalytic subunit P signature 173 192 2.2E-42 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS07695 67a952c0669fde68fd788e05263ec27b 212 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 117 130 - T 23-04-2016 IPR033135 ClpP, histidine active site DC74_RS07695 67a952c0669fde68fd788e05263ec27b 212 PANTHER PTHR10381 28 197 3.0E-98 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA DC74_RS14005 502b55fa6455916c52b61fa8de4a2f1f 340 PANTHER PTHR11732:SF225 7 334 6.7E-165 T 23-04-2016 DC74_RS14005 502b55fa6455916c52b61fa8de4a2f1f 340 SUPERFAMILY SSF51430 8 320 1.7E-90 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS14005 502b55fa6455916c52b61fa8de4a2f1f 340 Gene3D G3DSA:3.20.20.100 7 332 4.3E-105 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS14005 502b55fa6455916c52b61fa8de4a2f1f 340 PANTHER PTHR11732 7 334 6.7E-165 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS14005 502b55fa6455916c52b61fa8de4a2f1f 340 Pfam PF00248 Aldo/keto reductase family 23 318 6.3E-67 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS02800 74b6dd1f6b0f3adecb3b6e1e57b7b5de 245 SUPERFAMILY SSF52317 35 212 3.32E-22 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS02800 74b6dd1f6b0f3adecb3b6e1e57b7b5de 245 Pfam PF03575 Peptidase family S51 24 209 3.4E-29 T 23-04-2016 IPR005320 Peptidase S51 GO:0006508|GO:0008236 DC74_RS02800 74b6dd1f6b0f3adecb3b6e1e57b7b5de 245 Gene3D G3DSA:3.40.50.880 8 235 1.5E-42 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS02800 74b6dd1f6b0f3adecb3b6e1e57b7b5de 245 PANTHER PTHR20842:SF1 1 241 5.0E-72 T 23-04-2016 DC74_RS02800 74b6dd1f6b0f3adecb3b6e1e57b7b5de 245 PANTHER PTHR20842 1 241 5.0E-72 T 23-04-2016 DC74_RS09745 31701f6718e0f8c2864b2c208c0da09c 274 SUPERFAMILY SSF56752 1 263 1.7E-70 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS09745 31701f6718e0f8c2864b2c208c0da09c 274 Gene3D G3DSA:3.20.10.10 124 258 7.2E-43 T 23-04-2016 DC74_RS09745 31701f6718e0f8c2864b2c208c0da09c 274 Pfam PF01063 Amino-transferase class IV 29 243 1.1E-48 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS09745 31701f6718e0f8c2864b2c208c0da09c 274 Gene3D G3DSA:3.30.470.10 1 102 1.2E-31 T 23-04-2016 DC74_RS09745 31701f6718e0f8c2864b2c208c0da09c 274 PANTHER PTHR11825 3 271 2.1E-75 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS09745 31701f6718e0f8c2864b2c208c0da09c 274 ProSitePatterns PS00770 Aminotransferases class-IV signature. 174 203 - T 23-04-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS09745 31701f6718e0f8c2864b2c208c0da09c 274 PANTHER PTHR11825:SF55 3 271 2.1E-75 T 23-04-2016 DC74_RS37615 5e0750b9767e8359f9b1088e0f9bf5b9 729 Pfam PF09375 Imelysin 487 704 1.1E-15 T 23-04-2016 DC74_RS37615 5e0750b9767e8359f9b1088e0f9bf5b9 729 PANTHER PTHR31632 1 331 1.4E-57 T 23-04-2016 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 DC74_RS37615 5e0750b9767e8359f9b1088e0f9bf5b9 729 Pfam PF03239 Iron permease FTR1 family 6 258 1.5E-43 T 23-04-2016 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 Gene3D G3DSA:3.40.50.280 728 858 1.2E-46 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 TIGRFAM TIGR02082 metH: methionine synthase 18 1162 0.0 T 23-04-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 SUPERFAMILY SSF52242 725 860 2.22E-38 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 SUPERFAMILY SSF47644 642 724 2.48E-24 T 23-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 PANTHER PTHR21091 15 388 8.1E-119 T 23-04-2016 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 966 1164 7.7E-40 T 23-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 PANTHER PTHR21091:SF97 15 388 8.1E-119 T 23-04-2016 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 Gene3D G3DSA:3.20.20.330 8 352 7.3E-105 T 23-04-2016 IPR003726 Homocysteine-binding domain DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 Pfam PF02574 Homocysteine S-methyltransferase 22 313 5.7E-66 T 23-04-2016 IPR003726 Homocysteine-binding domain DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 Gene3D G3DSA:3.20.20.20 353 615 2.8E-84 T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 SUPERFAMILY SSF82282 12 387 6.67E-104 T 23-04-2016 IPR003726 Homocysteine-binding domain DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 SUPERFAMILY SSF51717 345 616 7.33E-74 T 23-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 Pfam PF02310 B12 binding domain 731 847 2.0E-20 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 Pfam PF02607 B12 binding domain 646 718 1.3E-24 T 23-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 Pfam PF00809 Pterin binding enzyme 348 584 5.5E-45 T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 SUPERFAMILY SSF56507 886 1164 1.7E-93 T 23-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 SMART SM01018 643 725 7.0E-42 T 23-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 Gene3D G3DSA:1.10.1240.10 637 722 1.7E-31 T 23-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 PIRSF PIRSF000381 6 1165 0.0 T 23-04-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 DC74_RS37255 bc429eba04bbef4718a56a9779473c97 1167 Gene3D G3DSA:3.10.196.10 943 1164 6.5E-70 T 23-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 DC74_RS17620 99f06451507624fc6e2831ca10814964 299 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 28 290 48.575 T 23-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 DC74_RS17620 99f06451507624fc6e2831ca10814964 299 Gene3D G3DSA:3.40.50.150 16 219 1.0E-65 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS17620 99f06451507624fc6e2831ca10814964 299 SUPERFAMILY SSF53335 28 287 4.34E-63 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS17620 99f06451507624fc6e2831ca10814964 299 PANTHER PTHR11727 18 287 5.3E-81 T 23-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm DC74_RS17620 99f06451507624fc6e2831ca10814964 299 SMART SM00650 44 218 9.9E-69 T 23-04-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 DC74_RS17620 99f06451507624fc6e2831ca10814964 299 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 60 87 - T 23-04-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 DC74_RS17620 99f06451507624fc6e2831ca10814964 299 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 28 287 2.9E-71 T 23-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 DC74_RS17620 99f06451507624fc6e2831ca10814964 299 Gene3D G3DSA:1.10.8.100 225 287 2.7E-20 T 23-04-2016 IPR023165 rRNA adenine dimethylase-like DC74_RS17620 99f06451507624fc6e2831ca10814964 299 Pfam PF00398 Ribosomal RNA adenine dimethylase 32 287 1.5E-43 T 23-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm DC74_RS03815 d50c2f35d5f86113d545b4b24c9fc27f 221 Gene3D G3DSA:3.40.1050.10 28 208 8.1E-41 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS03815 d50c2f35d5f86113d545b4b24c9fc27f 221 Pfam PF00484 Carbonic anhydrase 43 195 2.5E-32 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS03815 d50c2f35d5f86113d545b4b24c9fc27f 221 SUPERFAMILY SSF53056 25 208 6.28E-39 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS03815 d50c2f35d5f86113d545b4b24c9fc27f 221 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 48 55 - T 23-04-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS03815 d50c2f35d5f86113d545b4b24c9fc27f 221 SMART SM00947 36 200 1.2E-38 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS03815 d50c2f35d5f86113d545b4b24c9fc27f 221 PANTHER PTHR11002:SF13 40 215 1.6E-33 T 23-04-2016 DC74_RS03815 d50c2f35d5f86113d545b4b24c9fc27f 221 PANTHER PTHR11002 40 215 1.6E-33 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS02235 fbac34217698aa6e5f7835381ae2d70d 384 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 122 191 1.3E-10 T 23-04-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 DC74_RS02235 fbac34217698aa6e5f7835381ae2d70d 384 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 110 1.9E-16 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 DC74_RS02235 fbac34217698aa6e5f7835381ae2d70d 384 PANTHER PTHR22604 226 372 5.0E-66 T 23-04-2016 DC74_RS02235 fbac34217698aa6e5f7835381ae2d70d 384 PANTHER PTHR22604 7 195 5.0E-66 T 23-04-2016 DC74_RS02235 fbac34217698aa6e5f7835381ae2d70d 384 PANTHER PTHR22604:SF123 226 372 5.0E-66 T 23-04-2016 DC74_RS02235 fbac34217698aa6e5f7835381ae2d70d 384 PANTHER PTHR22604:SF123 7 195 5.0E-66 T 23-04-2016 DC74_RS02235 fbac34217698aa6e5f7835381ae2d70d 384 Gene3D G3DSA:3.30.360.10 127 362 3.3E-38 T 23-04-2016 DC74_RS02235 fbac34217698aa6e5f7835381ae2d70d 384 Gene3D G3DSA:3.40.50.720 15 126 8.8E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02235 fbac34217698aa6e5f7835381ae2d70d 384 SUPERFAMILY SSF51735 16 139 2.96E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02235 fbac34217698aa6e5f7835381ae2d70d 384 SUPERFAMILY SSF55347 116 331 1.16E-26 T 23-04-2016 DC74_RS16805 932c6452d27bedb5b196120fc28ea315 313 PANTHER PTHR30294 27 312 6.3E-61 T 23-04-2016 DC74_RS16805 932c6452d27bedb5b196120fc28ea315 313 PANTHER PTHR30294:SF14 27 312 6.3E-61 T 23-04-2016 DC74_RS16805 932c6452d27bedb5b196120fc28ea315 313 Pfam PF01061 ABC-2 type transporter 68 268 3.8E-13 T 23-04-2016 IPR013525 ABC-2 type transporter GO:0016020 DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 157 6.1E-15 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 PANTHER PTHR30173 4 286 1.2E-87 T 23-04-2016 DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 Pfam PF08281 Sigma-70, region 4 105 155 9.6E-12 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 PANTHER PTHR30173:SF25 4 286 1.2E-87 T 23-04-2016 DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 SUPERFAMILY SSF54427 166 283 4.29E-15 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 Pfam PF12680 SnoaL-like domain 175 256 6.4E-7 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 Gene3D G3DSA:3.10.450.50 166 283 4.3E-15 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 SUPERFAMILY SSF88659 80 158 3.55E-11 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 Pfam PF04542 Sigma-70 region 2 7 69 4.2E-11 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 Gene3D G3DSA:1.10.10.10 109 158 4.9E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 5 286 1.0E-108 T 23-04-2016 IPR014303 RNA polymerase sigma-70, ECF type DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 Gene3D G3DSA:1.10.1740.10 7 77 4.7E-10 T 23-04-2016 DC74_RS03900 8f1781af792441ceea2a54b8cf104a2e 308 SUPERFAMILY SSF88946 7 82 1.33E-11 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS06065 db911aad63ccbaf9840636c9d1af0631 480 PANTHER PTHR30572 437 479 3.7E-23 T 23-04-2016 DC74_RS06065 db911aad63ccbaf9840636c9d1af0631 480 PANTHER PTHR30572 176 404 3.7E-23 T 23-04-2016 DC74_RS06065 db911aad63ccbaf9840636c9d1af0631 480 Pfam PF02687 FtsX-like permease family 322 472 3.9E-13 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS06065 db911aad63ccbaf9840636c9d1af0631 480 PANTHER PTHR30572:SF11 437 479 3.7E-23 T 23-04-2016 DC74_RS06065 db911aad63ccbaf9840636c9d1af0631 480 PANTHER PTHR30572:SF11 176 404 3.7E-23 T 23-04-2016 DC74_RS25400 94557a26bff40c774b8cf30bdafdbf75 479 PANTHER PTHR13696 93 413 5.5E-92 T 23-04-2016 DC74_RS25400 94557a26bff40c774b8cf30bdafdbf75 479 SUPERFAMILY SSF52540 167 401 2.1E-32 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25400 94557a26bff40c774b8cf30bdafdbf75 479 PANTHER PTHR13696:SF68 93 413 5.5E-92 T 23-04-2016 DC74_RS25400 94557a26bff40c774b8cf30bdafdbf75 479 Gene3D G3DSA:3.40.50.300 166 401 2.4E-36 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25400 94557a26bff40c774b8cf30bdafdbf75 479 SUPERFAMILY SSF52172 4 42 1.46E-8 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS25400 94557a26bff40c774b8cf30bdafdbf75 479 SUPERFAMILY SSF52172 70 145 1.46E-8 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS25400 94557a26bff40c774b8cf30bdafdbf75 479 Gene3D G3DSA:3.40.50.2300 3 144 1.9E-9 T 23-04-2016 DC74_RS25400 94557a26bff40c774b8cf30bdafdbf75 479 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 168 347 2.8E-21 T 23-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DC74_RS09935 11ef7de469b04f3dfdb7e23c11aaf959 123 Gene3D G3DSA:3.10.180.10 7 118 2.5E-13 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS09935 11ef7de469b04f3dfdb7e23c11aaf959 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 118 4.1E-6 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS09935 11ef7de469b04f3dfdb7e23c11aaf959 123 SUPERFAMILY SSF54593 8 119 8.53E-16 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 SUPERFAMILY SSF88946 31 127 4.32E-31 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 PRINTS PR00046 Major sigma-70 factor signature 82 95 2.3E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 PRINTS PR00046 Major sigma-70 factor signature 246 261 2.3E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 PRINTS PR00046 Major sigma-70 factor signature 229 241 2.3E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 Pfam PF04542 Sigma-70 region 2 58 127 1.2E-17 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 82 95 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 SUPERFAMILY SSF88659 194 276 1.38E-17 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 55 275 3.7E-36 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 PANTHER PTHR30385 24 279 1.6E-132 T 23-04-2016 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 PANTHER PTHR30385:SF4 24 279 1.6E-132 T 23-04-2016 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 Pfam PF04539 Sigma-70 region 3 139 204 1.7E-10 T 23-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 Gene3D G3DSA:1.10.10.10 126 181 9.3E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 53 275 1.2E-94 T 23-04-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 SUPERFAMILY SSF88659 131 206 1.09E-13 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 Gene3D G3DSA:1.10.601.10 49 125 3.8E-24 T 23-04-2016 DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 Gene3D G3DSA:1.10.10.10 217 276 1.7E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21585 845f667c0ecb557fb0546aa0f366b470 279 Pfam PF04545 Sigma-70, region 4 225 274 1.1E-18 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS01350 d2de89d8ee951659a94a4215eed6a53e 532 SUPERFAMILY SSF52518 4 174 3.35E-37 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS01350 d2de89d8ee951659a94a4215eed6a53e 532 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 170 2.0E-37 T 23-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DC74_RS01350 d2de89d8ee951659a94a4215eed6a53e 532 Gene3D G3DSA:3.40.50.970 4 172 3.1E-40 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS01350 d2de89d8ee951659a94a4215eed6a53e 532 Gene3D G3DSA:3.40.50.1220 182 335 6.2E-40 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS01350 d2de89d8ee951659a94a4215eed6a53e 532 SUPERFAMILY SSF52518 349 526 4.29E-43 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS01350 d2de89d8ee951659a94a4215eed6a53e 532 Gene3D G3DSA:3.40.50.970 345 527 2.4E-45 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS01350 d2de89d8ee951659a94a4215eed6a53e 532 PANTHER PTHR18968 4 526 1.4E-169 T 23-04-2016 DC74_RS01350 d2de89d8ee951659a94a4215eed6a53e 532 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 384 519 9.3E-27 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS01350 d2de89d8ee951659a94a4215eed6a53e 532 SUPERFAMILY SSF52467 183 337 1.05E-50 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS01350 d2de89d8ee951659a94a4215eed6a53e 532 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 188 320 1.6E-14 T 23-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DC74_RS01350 d2de89d8ee951659a94a4215eed6a53e 532 PANTHER PTHR18968:SF133 4 526 1.4E-169 T 23-04-2016 DC74_RS05285 9adcb21082ce5ed969328f8e0da10594 354 Pfam PF01513 ATP-NAD kinase 35 301 2.6E-45 T 23-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS05285 9adcb21082ce5ed969328f8e0da10594 354 PANTHER PTHR20275 37 134 1.3E-62 T 23-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS05285 9adcb21082ce5ed969328f8e0da10594 354 PANTHER PTHR20275 166 315 1.3E-62 T 23-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS05285 9adcb21082ce5ed969328f8e0da10594 354 SUPERFAMILY SSF111331 168 316 4.97E-65 T 23-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain DC74_RS05285 9adcb21082ce5ed969328f8e0da10594 354 SUPERFAMILY SSF111331 5 134 4.97E-65 T 23-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain DC74_RS05285 9adcb21082ce5ed969328f8e0da10594 354 Gene3D G3DSA:3.40.50.10330 2 176 3.0E-26 T 23-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS05285 9adcb21082ce5ed969328f8e0da10594 354 Hamap MF_00361 NAD kinase [nadK]. 4 316 28.132 T 23-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS05285 9adcb21082ce5ed969328f8e0da10594 354 Gene3D G3DSA:2.60.200.30 177 291 7.3E-33 T 23-04-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS35140 02089e25b847bce184f9822028cbde04 247 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 156 190 5.3E-7 T 23-04-2016 IPR001451 Hexapeptide repeat DC74_RS35140 02089e25b847bce184f9822028cbde04 247 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 99 133 0.0012 T 23-04-2016 IPR001451 Hexapeptide repeat DC74_RS35140 02089e25b847bce184f9822028cbde04 247 PANTHER PTHR23416 86 231 1.3E-32 T 23-04-2016 DC74_RS35140 02089e25b847bce184f9822028cbde04 247 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 164 192 - T 23-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 DC74_RS35140 02089e25b847bce184f9822028cbde04 247 PANTHER PTHR23416:SF50 86 231 1.3E-32 T 23-04-2016 DC74_RS35140 02089e25b847bce184f9822028cbde04 247 SUPERFAMILY SSF51161 54 212 3.21E-35 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS35140 02089e25b847bce184f9822028cbde04 247 Gene3D G3DSA:2.160.10.10 62 213 3.4E-38 T 23-04-2016 DC74_RS34990 0ef85849f8be299dc9b476ada5fdb084 232 Pfam PF01464 Transglycosylase SLT domain 157 229 4.3E-11 T 23-04-2016 IPR008258 Transglycosylase SLT domain 1 DC74_RS34990 0ef85849f8be299dc9b476ada5fdb084 232 SUPERFAMILY SSF53955 141 226 4.22E-15 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS34990 0ef85849f8be299dc9b476ada5fdb084 232 Gene3D G3DSA:1.10.530.10 153 229 3.0E-10 T 23-04-2016 DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 SUPERFAMILY SSF55031 303 340 1.02E-8 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 SUPERFAMILY SSF55031 213 255 1.02E-8 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 Gene3D G3DSA:3.40.630.10 389 452 4.4E-57 T 23-04-2016 DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 Gene3D G3DSA:3.40.630.10 22 222 4.4E-57 T 23-04-2016 DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 Pfam PF01546 Peptidase family M20/M25/M40 93 452 7.1E-36 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 PANTHER PTHR11014:SF106 11 268 1.4E-105 T 23-04-2016 DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 PANTHER PTHR11014:SF106 291 456 1.4E-105 T 23-04-2016 DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 Gene3D G3DSA:3.30.70.360 223 262 2.3E-21 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 Gene3D G3DSA:3.30.70.360 304 340 2.3E-21 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 127 166 - T 23-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 SUPERFAMILY SSF53187 21 213 1.14E-53 T 23-04-2016 DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 SUPERFAMILY SSF53187 364 452 1.14E-53 T 23-04-2016 DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 Pfam PF07687 Peptidase dimerisation domain 211 340 1.7E-13 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 92 101 - T 23-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 PANTHER PTHR11014 11 268 1.4E-105 T 23-04-2016 DC74_RS31850 27a4a4cb8b6052af36f8abc707f63f8e 458 PANTHER PTHR11014 291 456 1.4E-105 T 23-04-2016 DC74_RS07410 9b88d96a2a36fe7d0955119c244a0890 609 Pfam PF14863 Alkyl sulfatase dimerisation 337 473 9.9E-55 T 23-04-2016 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 DC74_RS07410 9b88d96a2a36fe7d0955119c244a0890 609 Gene3D G3DSA:3.60.15.10 66 164 1.1E-37 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS07410 9b88d96a2a36fe7d0955119c244a0890 609 Gene3D G3DSA:3.60.15.10 206 330 1.1E-37 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS07410 9b88d96a2a36fe7d0955119c244a0890 609 Pfam PF00753 Metallo-beta-lactamase superfamily 77 300 1.5E-31 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS07410 9b88d96a2a36fe7d0955119c244a0890 609 SMART SM00849 81 300 1.3E-20 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS07410 9b88d96a2a36fe7d0955119c244a0890 609 PANTHER PTHR11935 33 166 1.8E-151 T 23-04-2016 DC74_RS07410 9b88d96a2a36fe7d0955119c244a0890 609 SUPERFAMILY SSF55718 491 609 9.81E-19 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS07410 9b88d96a2a36fe7d0955119c244a0890 609 PANTHER PTHR11935 190 425 1.8E-151 T 23-04-2016 DC74_RS07410 9b88d96a2a36fe7d0955119c244a0890 609 Pfam PF14864 Alkyl sulfatase C-terminal 490 609 1.8E-28 T 23-04-2016 IPR029229 Alkyl sulfatase, C-terminal DC74_RS07410 9b88d96a2a36fe7d0955119c244a0890 609 PANTHER PTHR11935:SF93 33 166 1.8E-151 T 23-04-2016 DC74_RS07410 9b88d96a2a36fe7d0955119c244a0890 609 SUPERFAMILY SSF56281 2 475 3.36E-136 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS07410 9b88d96a2a36fe7d0955119c244a0890 609 PANTHER PTHR11935:SF93 190 425 1.8E-151 T 23-04-2016 DC74_RS19755 69536f2a8245930bb529e946463dcca2 299 ProSitePatterns PS01058 SAICAR synthetase signature 2. 204 212 - T 23-04-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 DC74_RS19755 69536f2a8245930bb529e946463dcca2 299 PANTHER PTHR11609:SF6 11 295 7.4E-114 T 23-04-2016 DC74_RS19755 69536f2a8245930bb529e946463dcca2 299 Gene3D G3DSA:3.30.470.20 117 247 1.2E-55 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS19755 69536f2a8245930bb529e946463dcca2 299 Gene3D G3DSA:3.30.200.20 11 116 2.7E-43 T 23-04-2016 DC74_RS19755 69536f2a8245930bb529e946463dcca2 299 Pfam PF01259 SAICAR synthetase 18 268 1.9E-101 T 23-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 DC74_RS19755 69536f2a8245930bb529e946463dcca2 299 SUPERFAMILY SSF56104 12 298 1.86E-100 T 23-04-2016 DC74_RS19755 69536f2a8245930bb529e946463dcca2 299 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 16 295 26.015 T 23-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 DC74_RS19755 69536f2a8245930bb529e946463dcca2 299 ProSitePatterns PS01057 SAICAR synthetase signature 1. 105 119 - T 23-04-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 DC74_RS19755 69536f2a8245930bb529e946463dcca2 299 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 18 297 5.4E-72 T 23-04-2016 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 DC74_RS19755 69536f2a8245930bb529e946463dcca2 299 PANTHER PTHR11609 11 295 7.4E-114 T 23-04-2016 DC74_RS00900 5b7b18fabaf708f395d947b2e2b44e72 283 SUPERFAMILY SSF53335 13 269 6.98E-63 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS00900 5b7b18fabaf708f395d947b2e2b44e72 283 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 15 263 1.1E-84 T 23-04-2016 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS00900 5b7b18fabaf708f395d947b2e2b44e72 283 PANTHER PTHR13600 1 203 1.1E-57 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS00900 5b7b18fabaf708f395d947b2e2b44e72 283 Pfam PF04072 Leucine carboxyl methyltransferase 17 193 2.5E-55 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS00900 5b7b18fabaf708f395d947b2e2b44e72 283 PANTHER PTHR13600:SF12 1 203 1.1E-57 T 23-04-2016 DC74_RS00900 5b7b18fabaf708f395d947b2e2b44e72 283 Gene3D G3DSA:3.40.50.150 22 197 6.8E-20 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS26005 b6f2605db1339de52262a0b89208d992 203 PANTHER PTHR41386 30 203 2.5E-54 T 23-04-2016 DC74_RS26005 b6f2605db1339de52262a0b89208d992 203 Pfam PF06210 Protein of unknown function (DUF1003) 71 172 1.9E-40 T 23-04-2016 IPR010406 Protein of unknown function DUF1003 DC74_RS26005 b6f2605db1339de52262a0b89208d992 203 PANTHER PTHR41386:SF1 30 203 2.5E-54 T 23-04-2016 DC74_RS17825 bbbf5c6c2224663916b91377e1b92b6f 207 SUPERFAMILY SSF55729 2 179 9.19E-42 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS17825 bbbf5c6c2224663916b91377e1b92b6f 207 Gene3D G3DSA:3.40.630.30 2 185 5.6E-59 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS17825 bbbf5c6c2224663916b91377e1b92b6f 207 PANTHER PTHR13256 1 202 3.7E-39 T 23-04-2016 DC74_RS17825 bbbf5c6c2224663916b91377e1b92b6f 207 PANTHER PTHR13256:SF24 1 202 3.7E-39 T 23-04-2016 DC74_RS17825 bbbf5c6c2224663916b91377e1b92b6f 207 Pfam PF13302 Acetyltransferase (GNAT) domain 9 155 3.3E-16 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS22960 b87c3a832aa4d40fdff515323d056bec 375 PANTHER PTHR30570:SF0 39 373 4.7E-102 T 23-04-2016 DC74_RS22960 b87c3a832aa4d40fdff515323d056bec 375 Gene3D G3DSA:3.40.190.10 236 373 1.2E-15 T 23-04-2016 DC74_RS22960 b87c3a832aa4d40fdff515323d056bec 375 Gene3D G3DSA:3.40.190.10 54 209 5.9E-45 T 23-04-2016 DC74_RS22960 b87c3a832aa4d40fdff515323d056bec 375 Pfam PF12849 PBP superfamily domain 54 344 1.3E-57 T 23-04-2016 IPR024370 PBP domain DC74_RS22960 b87c3a832aa4d40fdff515323d056bec 375 PANTHER PTHR30570 39 373 4.7E-102 T 23-04-2016 DC74_RS22960 b87c3a832aa4d40fdff515323d056bec 375 PIRSF PIRSF002756 11 375 9.0E-122 T 23-04-2016 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 DC74_RS22960 b87c3a832aa4d40fdff515323d056bec 375 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 58 373 1.4E-79 T 23-04-2016 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 DC74_RS22960 b87c3a832aa4d40fdff515323d056bec 375 SUPERFAMILY SSF53850 56 375 3.12E-87 T 23-04-2016 DC74_RS25665 64aa81d1234bed020325617de66d2e6d 60 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 9 56 2.7E-8 T 23-04-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 DC74_RS25665 64aa81d1234bed020325617de66d2e6d 60 Pfam PF12728 Helix-turn-helix domain 9 58 3.7E-13 T 23-04-2016 DC74_RS25665 64aa81d1234bed020325617de66d2e6d 60 SUPERFAMILY SSF46955 8 58 1.5E-6 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS25665 64aa81d1234bed020325617de66d2e6d 60 Gene3D G3DSA:1.10.10.10 9 58 5.0E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10370 e331bca225f987fc85a5c880cd6e22a4 535 PANTHER PTHR30290:SF7 1 531 7.0E-165 T 23-04-2016 DC74_RS10370 e331bca225f987fc85a5c880cd6e22a4 535 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 451 4.6E-75 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain DC74_RS10370 e331bca225f987fc85a5c880cd6e22a4 535 Gene3D G3DSA:3.40.190.10 144 299 3.5E-35 T 23-04-2016 DC74_RS10370 e331bca225f987fc85a5c880cd6e22a4 535 SUPERFAMILY SSF53850 48 518 1.63E-97 T 23-04-2016 DC74_RS10370 e331bca225f987fc85a5c880cd6e22a4 535 Gene3D G3DSA:3.10.105.10 300 501 4.1E-45 T 23-04-2016 DC74_RS10370 e331bca225f987fc85a5c880cd6e22a4 535 PANTHER PTHR30290 1 531 7.0E-165 T 23-04-2016 DC74_RS10370 e331bca225f987fc85a5c880cd6e22a4 535 PIRSF PIRSF002741 1 529 1.5E-76 T 23-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 Gene3D G3DSA:1.10.1200.10 1 53 1.7E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 SUPERFAMILY SSF47336 92 122 7.07E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 SUPERFAMILY SSF47336 2 55 7.07E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 109 355 1.1E-81 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 SUPERFAMILY SSF53901 106 473 5.46E-87 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 SUPERFAMILY SSF53901 514 534 5.46E-87 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 Pfam PF00550 Phosphopantetheine attachment site 4 50 2.5E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 483 572 1.5E-14 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 SMART SM00825 Beta-ketoacyl synthase 110 538 4.9E-192 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 PANTHER PTHR11712:SF288 105 573 1.3E-191 T 23-04-2016 DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 363 480 2.3E-41 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 SMART SM00823 Phosphopantetheine attachment site 2 54 0.0053 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 PANTHER PTHR11712 105 573 1.3E-191 T 23-04-2016 DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 Gene3D G3DSA:3.40.47.10 111 367 3.2E-87 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40530 e78843dc34791ad1f576f5d6e533f5aa 649 Gene3D G3DSA:3.40.47.10 368 538 4.7E-60 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22275 a4794a6488f585dc35d25a790c7b7256 77 Pfam PF03777 Small secreted domain (DUF320) 21 76 1.6E-29 T 23-04-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species DC74_RS29540 36ac370fc8a391308e1c1817f9953657 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 484 6.2E-6 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS29540 36ac370fc8a391308e1c1817f9953657 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 147 158 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS29540 36ac370fc8a391308e1c1817f9953657 511 Gene3D G3DSA:3.40.50.980 154 306 4.5E-26 T 23-04-2016 DC74_RS29540 36ac370fc8a391308e1c1817f9953657 511 Pfam PF00501 AMP-binding enzyme 20 400 5.0E-49 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS29540 36ac370fc8a391308e1c1817f9953657 511 PANTHER PTHR24096 15 492 6.8E-40 T 23-04-2016 DC74_RS29540 36ac370fc8a391308e1c1817f9953657 511 Gene3D G3DSA:2.30.38.10 310 399 8.7E-11 T 23-04-2016 DC74_RS29540 36ac370fc8a391308e1c1817f9953657 511 SUPERFAMILY SSF56801 12 496 9.55E-75 T 23-04-2016 DC74_RS29540 36ac370fc8a391308e1c1817f9953657 511 Gene3D G3DSA:3.30.300.30 422 496 1.9E-12 T 23-04-2016 DC74_RS29540 36ac370fc8a391308e1c1817f9953657 511 Gene3D G3DSA:3.40.50.980 19 153 4.7E-13 T 23-04-2016 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 21 74 0.002 T 23-04-2016 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 PANTHER PTHR21342 6 166 6.1E-82 T 23-04-2016 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 PANTHER PTHR21342:SF1 6 166 6.1E-82 T 23-04-2016 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 95 111 1.8E-49 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 121 143 1.8E-49 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 30 51 1.8E-49 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 59 83 1.8E-49 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 12 30 1.8E-49 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 Pfam PF01467 Cytidylyltransferase-like 16 142 2.0E-18 T 23-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 SUPERFAMILY SSF52374 12 164 2.36E-45 T 23-04-2016 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 12 167 34.743 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 13 165 9.9E-59 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 69 4.0E-15 T 23-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DC74_RS27990 87246ebb474a515dfadf80f88c48c5ef 170 Gene3D G3DSA:3.40.50.620 6 165 1.2E-52 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS26035 b62a753f48499a25cb459ca9b9564076 437 PRINTS PR01035 Tetracycline resistance protein signature 170 192 7.4E-12 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 DC74_RS26035 b62a753f48499a25cb459ca9b9564076 437 PRINTS PR01035 Tetracycline resistance protein signature 56 72 7.4E-12 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 DC74_RS26035 b62a753f48499a25cb459ca9b9564076 437 PRINTS PR01035 Tetracycline resistance protein signature 198 218 7.4E-12 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 DC74_RS26035 b62a753f48499a25cb459ca9b9564076 437 PANTHER PTHR23501 38 433 1.0E-190 T 23-04-2016 DC74_RS26035 b62a753f48499a25cb459ca9b9564076 437 Pfam PF07690 Major Facilitator Superfamily 53 298 5.8E-28 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS26035 b62a753f48499a25cb459ca9b9564076 437 Gene3D G3DSA:1.20.1250.20 245 412 4.6E-14 T 23-04-2016 DC74_RS26035 b62a753f48499a25cb459ca9b9564076 437 Gene3D G3DSA:1.20.1250.20 46 227 3.3E-27 T 23-04-2016 DC74_RS26035 b62a753f48499a25cb459ca9b9564076 437 PANTHER PTHR23501:SF72 38 433 1.0E-190 T 23-04-2016 DC74_RS26035 b62a753f48499a25cb459ca9b9564076 437 SUPERFAMILY SSF103473 34 412 5.49E-55 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS34170 753db85e8c7c8b46038720b6fb4884dc 359 ProSitePatterns PS01095 Chitinases family 18 active site. 167 175 - T 23-04-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 DC74_RS34170 753db85e8c7c8b46038720b6fb4884dc 359 PANTHER PTHR11177 24 352 3.6E-29 T 23-04-2016 DC74_RS34170 753db85e8c7c8b46038720b6fb4884dc 359 SMART SM00636 53 342 0.0013 T 23-04-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 DC74_RS34170 753db85e8c7c8b46038720b6fb4884dc 359 Gene3D G3DSA:3.20.20.80 53 349 2.5E-41 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS34170 753db85e8c7c8b46038720b6fb4884dc 359 PANTHER PTHR11177:SF195 24 352 3.6E-29 T 23-04-2016 DC74_RS34170 753db85e8c7c8b46038720b6fb4884dc 359 SUPERFAMILY SSF51445 52 349 1.19E-43 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS34170 753db85e8c7c8b46038720b6fb4884dc 359 Pfam PF00704 Glycosyl hydrolases family 18 55 342 3.0E-20 T 23-04-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 DC74_RS20720 3ce4bcc816c7666aca9a9e755ced1143 241 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 15 210 24.528 T 23-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 DC74_RS20720 3ce4bcc816c7666aca9a9e755ced1143 241 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 28 197 1.6E-38 T 23-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 DC74_RS20720 3ce4bcc816c7666aca9a9e755ced1143 241 Pfam PF02527 rRNA small subunit methyltransferase G 25 199 7.6E-56 T 23-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 DC74_RS20720 3ce4bcc816c7666aca9a9e755ced1143 241 PANTHER PTHR31760 17 195 1.2E-56 T 23-04-2016 DC74_RS20720 3ce4bcc816c7666aca9a9e755ced1143 241 PANTHER PTHR31760:SF0 17 195 1.2E-56 T 23-04-2016 DC74_RS20720 3ce4bcc816c7666aca9a9e755ced1143 241 SUPERFAMILY SSF53335 27 208 1.51E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS20720 3ce4bcc816c7666aca9a9e755ced1143 241 Gene3D G3DSA:3.40.50.150 27 213 3.0E-62 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 Pfam PF01590 GAF domain 339 434 2.4E-8 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 Pfam PF13426 PAS domain 22 109 9.1E-7 T 23-04-2016 IPR000014 PAS domain DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 SUPERFAMILY SSF55781 367 447 1.92E-12 T 23-04-2016 IPR029016 GAF domain-like DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 SUPERFAMILY SSF81606 482 683 3.92E-5 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 SUPERFAMILY SSF55874 729 806 1.16E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 Gene3D G3DSA:3.30.450.20 128 247 8.0E-19 T 23-04-2016 DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 SMART SM00065 252 444 4.5E-5 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 492 684 3.0E-44 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 Gene3D G3DSA:3.30.450.40 258 442 1.3E-31 T 23-04-2016 IPR029016 GAF domain-like DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 Pfam PF08448 PAS fold 138 249 5.1E-20 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 128 254 1.3E-8 T 23-04-2016 IPR000014 PAS domain DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 112 1.1E-11 T 23-04-2016 IPR000014 PAS domain DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 PANTHER PTHR21021:SF19 390 693 5.4E-48 T 23-04-2016 DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 PANTHER PTHR21021 390 693 5.4E-48 T 23-04-2016 DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 Pfam PF13581 Histidine kinase-like ATPase domain 698 805 5.6E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 SMART SM00091 10 76 0.046 T 23-04-2016 IPR000014 PAS domain DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 SMART SM00091 130 196 1.4E-4 T 23-04-2016 IPR000014 PAS domain DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 SUPERFAMILY SSF55785 14 115 7.73E-17 T 23-04-2016 IPR000014 PAS domain DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 Gene3D G3DSA:3.30.450.20 16 115 3.6E-16 T 23-04-2016 DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 SUPERFAMILY SSF55785 128 245 4.54E-14 T 23-04-2016 IPR000014 PAS domain DC74_RS36500 28e4889e5783bbc696a5972fb7efaeb3 811 SMART SM00331 465 684 6.0E-34 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 SUPERFAMILY SSF55060 211 388 1.98E-45 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 Gene3D G3DSA:3.30.70.890 215 387 3.6E-49 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 ProSitePatterns PS00106 Galactokinase signature. 31 42 - T 23-04-2016 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 TIGRFAM TIGR00131 gal_kin: galactokinase 11 366 2.1E-81 T 23-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 PANTHER PTHR10457 9 390 2.6E-116 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 Pfam PF08544 GHMP kinases C terminal 292 367 2.0E-11 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 Gene3D G3DSA:3.30.230.10 10 214 3.2E-71 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 PIRSF PIRSF000530 1 390 4.5E-118 T 23-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 PRINTS PR00473 Galactokinase signature 116 134 3.6E-22 T 23-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 PRINTS PR00473 Galactokinase signature 272 286 3.6E-22 T 23-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 PRINTS PR00473 Galactokinase signature 31 49 3.6E-22 T 23-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 PRINTS PR00473 Galactokinase signature 96 107 3.6E-22 T 23-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 PRINTS PR00959 Mevalonate kinase family signature 166 185 2.2E-40 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 PRINTS PR00959 Mevalonate kinase family signature 335 352 2.2E-40 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 PRINTS PR00959 Mevalonate kinase family signature 29 53 2.2E-40 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 PRINTS PR00959 Mevalonate kinase family signature 123 145 2.2E-40 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 Hamap MF_00246 Galactokinase [galK]. 29 388 40.986 T 23-04-2016 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 SUPERFAMILY SSF54211 10 206 4.17E-61 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 Pfam PF00288 GHMP kinases N terminal domain 118 184 7.9E-17 T 23-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 125 136 - T 23-04-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 PANTHER PTHR10457:SF6 9 390 2.6E-116 T 23-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17550 39cb19c2d4eeb7d7c1acc133109f0bc2 391 Pfam PF10509 Galactokinase galactose-binding signature 14 62 1.3E-20 T 23-04-2016 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS16170 0ab61dfcddd0a986e3a38586bfd70030 259 Pfam PF13242 HAD-hyrolase-like 182 255 8.2E-23 T 23-04-2016 DC74_RS16170 0ab61dfcddd0a986e3a38586bfd70030 259 PIRSF PIRSF000915 3 259 3.3E-52 T 23-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA DC74_RS16170 0ab61dfcddd0a986e3a38586bfd70030 259 Gene3D G3DSA:3.40.50.1000 182 258 7.8E-43 T 23-04-2016 IPR023214 HAD-like domain DC74_RS16170 0ab61dfcddd0a986e3a38586bfd70030 259 Gene3D G3DSA:3.40.50.1000 6 83 7.8E-43 T 23-04-2016 IPR023214 HAD-like domain DC74_RS16170 0ab61dfcddd0a986e3a38586bfd70030 259 SUPERFAMILY SSF56784 7 257 8.41E-70 T 23-04-2016 IPR023214 HAD-like domain DC74_RS16170 0ab61dfcddd0a986e3a38586bfd70030 259 PANTHER PTHR19288:SF40 1 259 2.2E-151 T 23-04-2016 DC74_RS16170 0ab61dfcddd0a986e3a38586bfd70030 259 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 231 5.2E-46 T 23-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA DC74_RS16170 0ab61dfcddd0a986e3a38586bfd70030 259 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 109 1.8E-25 T 23-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA DC74_RS16170 0ab61dfcddd0a986e3a38586bfd70030 259 Gene3D G3DSA:3.40.50.10410 88 181 1.6E-33 T 23-04-2016 IPR023215 Nitrophenylphosphatase-like domain DC74_RS16170 0ab61dfcddd0a986e3a38586bfd70030 259 PANTHER PTHR19288 1 259 2.2E-151 T 23-04-2016 DC74_RS15490 952bc22b1d5c51606c9da8002c075acc 378 PANTHER PTHR18964 47 372 1.8E-65 T 23-04-2016 DC74_RS15490 952bc22b1d5c51606c9da8002c075acc 378 Gene3D G3DSA:1.10.10.10 6 64 3.5E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS15490 952bc22b1d5c51606c9da8002c075acc 378 Gene3D G3DSA:3.30.420.40 67 210 8.5E-38 T 23-04-2016 DC74_RS15490 952bc22b1d5c51606c9da8002c075acc 378 SUPERFAMILY SSF46785 1 64 6.31E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS15490 952bc22b1d5c51606c9da8002c075acc 378 Gene3D G3DSA:3.30.420.40 211 348 2.3E-29 T 23-04-2016 DC74_RS15490 952bc22b1d5c51606c9da8002c075acc 378 Pfam PF00480 ROK family 81 327 3.6E-31 T 23-04-2016 IPR000600 ROK family DC74_RS15490 952bc22b1d5c51606c9da8002c075acc 378 PANTHER PTHR18964:SF108 47 372 1.8E-65 T 23-04-2016 DC74_RS15490 952bc22b1d5c51606c9da8002c075acc 378 Pfam PF12802 MarR family 5 49 6.3E-8 T 23-04-2016 DC74_RS15490 952bc22b1d5c51606c9da8002c075acc 378 SUPERFAMILY SSF53067 80 370 4.21E-39 T 23-04-2016 DC74_RS32610 67cb1cc91d7f77d1aa706f670d618676 351 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 351 75.657 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 DC74_RS32610 67cb1cc91d7f77d1aa706f670d618676 351 Gene3D G3DSA:3.40.440.10 3 95 2.0E-41 T 23-04-2016 DC74_RS32610 67cb1cc91d7f77d1aa706f670d618676 351 Gene3D G3DSA:3.40.440.10 142 217 2.0E-41 T 23-04-2016 DC74_RS32610 67cb1cc91d7f77d1aa706f670d618676 351 Gene3D G3DSA:3.90.170.10 294 329 1.7E-4 T 23-04-2016 DC74_RS32610 67cb1cc91d7f77d1aa706f670d618676 351 Gene3D G3DSA:3.90.170.10 218 287 8.0E-20 T 23-04-2016 DC74_RS32610 67cb1cc91d7f77d1aa706f670d618676 351 PANTHER PTHR11846 4 334 7.6E-73 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 DC74_RS32610 67cb1cc91d7f77d1aa706f670d618676 351 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-04-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 DC74_RS32610 67cb1cc91d7f77d1aa706f670d618676 351 Pfam PF00709 Adenylosuccinate synthetase 4 146 5.0E-30 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 DC74_RS32610 67cb1cc91d7f77d1aa706f670d618676 351 Pfam PF00709 Adenylosuccinate synthetase 148 287 5.7E-36 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 DC74_RS32610 67cb1cc91d7f77d1aa706f670d618676 351 SUPERFAMILY SSF52540 2 329 5.31E-84 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32610 67cb1cc91d7f77d1aa706f670d618676 351 SMART SM00788 3 330 1.7E-88 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 DC74_RS39315 8faa4240bfa6ecc48e4c0e7de281851b 281 SUPERFAMILY SSF56281 55 246 1.13E-25 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS39315 8faa4240bfa6ecc48e4c0e7de281851b 281 Gene3D G3DSA:3.60.15.10 58 242 4.3E-29 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS39315 8faa4240bfa6ecc48e4c0e7de281851b 281 Pfam PF00753 Metallo-beta-lactamase superfamily 79 206 2.9E-7 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS39315 8faa4240bfa6ecc48e4c0e7de281851b 281 PANTHER PTHR36839:SF1 3 280 8.9E-81 T 23-04-2016 DC74_RS39315 8faa4240bfa6ecc48e4c0e7de281851b 281 SMART SM00849 74 245 4.0E-4 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS39315 8faa4240bfa6ecc48e4c0e7de281851b 281 PANTHER PTHR36839 3 280 8.9E-81 T 23-04-2016 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 Pfam PF01494 FAD binding domain 9 361 5.1E-110 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 PANTHER PTHR13789:SF219 8 365 1.4E-146 T 23-04-2016 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 Gene3D G3DSA:3.50.50.60 309 337 3.9E-51 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 Gene3D G3DSA:3.50.50.60 4 193 3.9E-51 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 SUPERFAMILY SSF51905 9 190 4.45E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 SUPERFAMILY SSF51905 286 369 4.45E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 332 350 7.0E-42 T 23-04-2016 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 314 7.0E-42 T 23-04-2016 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 169 184 7.0E-42 T 23-04-2016 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 7.0E-42 T 23-04-2016 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 330 7.0E-42 T 23-04-2016 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 350 366 7.0E-42 T 23-04-2016 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 Gene3D G3DSA:3.30.9.10 252 308 9.7E-4 T 23-04-2016 DC74_RS07510 d6e8075d3b912f96039eeeab72f957e1 544 PANTHER PTHR13789 8 365 1.4E-146 T 23-04-2016 DC74_RS32990 eb9283908b042fb61634e93fba01ba08 395 SUPERFAMILY SSF51735 14 165 2.46E-13 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32990 eb9283908b042fb61634e93fba01ba08 395 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 14 140 1.1E-10 T 23-04-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 DC74_RS32990 eb9283908b042fb61634e93fba01ba08 395 PANTHER PTHR12286:SF4 1 392 1.2E-112 T 23-04-2016 DC74_RS32990 eb9283908b042fb61634e93fba01ba08 395 PANTHER PTHR12286 1 392 1.2E-112 T 23-04-2016 DC74_RS32990 eb9283908b042fb61634e93fba01ba08 395 Gene3D G3DSA:3.40.50.720 14 163 1.9E-15 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06215 1ad9109ca55f33cb04cb88080f8038d8 519 PANTHER PTHR24362:SF247 1 268 1.1E-76 T 23-04-2016 DC74_RS06215 1ad9109ca55f33cb04cb88080f8038d8 519 SUPERFAMILY SSF56112 12 268 3.99E-59 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS06215 1ad9109ca55f33cb04cb88080f8038d8 519 Gene3D G3DSA:3.30.200.20 10 70 1.5E-10 T 23-04-2016 DC74_RS06215 1ad9109ca55f33cb04cb88080f8038d8 519 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS06215 1ad9109ca55f33cb04cb88080f8038d8 519 Gene3D G3DSA:1.10.510.10 71 264 8.8E-40 T 23-04-2016 DC74_RS06215 1ad9109ca55f33cb04cb88080f8038d8 519 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 42 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS06215 1ad9109ca55f33cb04cb88080f8038d8 519 PANTHER PTHR24362 1 268 1.1E-76 T 23-04-2016 DC74_RS06215 1ad9109ca55f33cb04cb88080f8038d8 519 SMART SM00220 14 265 2.1E-35 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS06215 1ad9109ca55f33cb04cb88080f8038d8 519 Pfam PF00069 Protein kinase domain 14 262 4.0E-35 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 SUPERFAMILY SSF52210 129 287 1.44E-46 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 1.6E-34 T 23-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 1.6E-34 T 23-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 1.6E-34 T 23-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 1.6E-34 T 23-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 23-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 Gene3D G3DSA:3.40.50.261 126 290 1.2E-65 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 PIRSF PIRSF001553 1 293 1.6E-113 T 23-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 Gene3D G3DSA:3.40.50.720 3 125 3.0E-47 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS24530 17cb92376d282841691737acfb9877ba 294 SUPERFAMILY SSF51735 1 128 1.67E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS24530 17cb92376d282841691737acfb9877ba 294 Pfam PF00549 CoA-ligase 158 275 4.5E-13 T 23-04-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 Pfam PF02629 CoA binding domain 6 103 6.6E-26 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 23-04-2016 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site DC74_RS24530 17cb92376d282841691737acfb9877ba 294 SMART SM00881 4 104 8.4E-30 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 292 4.9E-126 T 23-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 DC74_RS24530 17cb92376d282841691737acfb9877ba 294 PANTHER PTHR11117 1 292 2.1E-146 T 23-04-2016 DC74_RS32905 46f78ba42bc66fb138c958e7a0f13bec 136 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 22 119 4.4E-31 T 23-04-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 DC74_RS39595 e0fdeadd9ba88e1828321dbd6c6472e1 266 PANTHER PTHR11695:SF605 20 265 1.3E-22 T 23-04-2016 DC74_RS39595 e0fdeadd9ba88e1828321dbd6c6472e1 266 SMART SM00829 15 262 1.2E-6 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS39595 e0fdeadd9ba88e1828321dbd6c6472e1 266 Pfam PF13602 Zinc-binding dehydrogenase 136 262 5.8E-12 T 23-04-2016 DC74_RS39595 e0fdeadd9ba88e1828321dbd6c6472e1 266 PANTHER PTHR11695 20 265 1.3E-22 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS39595 e0fdeadd9ba88e1828321dbd6c6472e1 266 Gene3D G3DSA:3.90.180.10 7 214 1.6E-28 T 23-04-2016 IPR011032 GroES-like DC74_RS39595 e0fdeadd9ba88e1828321dbd6c6472e1 266 SUPERFAMILY SSF50129 6 132 2.36E-26 T 23-04-2016 IPR011032 GroES-like DC74_RS39595 e0fdeadd9ba88e1828321dbd6c6472e1 266 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 97 6.4E-5 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS36695 239f164e1efd8d94cd4d93c9e11ff44f 436 SMART SM00327 51 241 7.4E-20 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS36695 239f164e1efd8d94cd4d93c9e11ff44f 436 Gene3D G3DSA:3.40.50.410 55 238 2.6E-13 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS36695 239f164e1efd8d94cd4d93c9e11ff44f 436 Pfam PF13519 von Willebrand factor type A domain 55 170 4.5E-12 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS36695 239f164e1efd8d94cd4d93c9e11ff44f 436 SUPERFAMILY SSF53300 54 238 1.54E-24 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS36695 239f164e1efd8d94cd4d93c9e11ff44f 436 PANTHER PTHR10579 56 231 1.2E-23 T 23-04-2016 DC74_RS31465 a224bdd51a9f2054b17b74339ee082e2 222 PANTHER PTHR30246:SF4 1 209 1.0E-64 T 23-04-2016 DC74_RS31465 a224bdd51a9f2054b17b74339ee082e2 222 PANTHER PTHR30246 1 209 1.0E-64 T 23-04-2016 DC74_RS31465 a224bdd51a9f2054b17b74339ee082e2 222 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 12 206 6.4E-48 T 23-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 DC74_RS31465 a224bdd51a9f2054b17b74339ee082e2 222 Pfam PF01081 KDPG and KHG aldolase 13 188 8.9E-39 T 23-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 DC74_RS31465 a224bdd51a9f2054b17b74339ee082e2 222 SUPERFAMILY SSF51569 5 197 2.56E-54 T 23-04-2016 DC74_RS31465 a224bdd51a9f2054b17b74339ee082e2 222 Gene3D G3DSA:3.20.20.70 8 203 2.9E-63 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS08845 cc0bcb3a21f2b64d1701d2f0ea968718 415 SUPERFAMILY SSF55874 285 403 1.55E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS08845 cc0bcb3a21f2b64d1701d2f0ea968718 415 PANTHER PTHR24421 78 415 7.0E-98 T 23-04-2016 DC74_RS08845 cc0bcb3a21f2b64d1701d2f0ea968718 415 Gene3D G3DSA:3.30.565.10 286 404 6.1E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS08845 cc0bcb3a21f2b64d1701d2f0ea968718 415 PANTHER PTHR24421:SF26 78 415 7.0E-98 T 23-04-2016 DC74_RS08845 cc0bcb3a21f2b64d1701d2f0ea968718 415 Pfam PF07730 Histidine kinase 205 270 3.6E-20 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 SUPERFAMILY SSF144010 12 223 5.75E-64 T 23-04-2016 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 Gene3D G3DSA:3.90.1660.10 68 128 4.1E-22 T 23-04-2016 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 11 218 4.4E-71 T 23-04-2016 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199|UniPathway: UPA00071 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 Pfam PF01996 F420-0:Gamma-glutamyl ligase 18 76 2.8E-10 T 23-04-2016 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199|UniPathway: UPA00071 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 Pfam PF01996 F420-0:Gamma-glutamyl ligase 91 214 3.5E-33 T 23-04-2016 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199|UniPathway: UPA00071 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 267 460 2.3E-95 T 23-04-2016 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199|UniPathway: UPA00071 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 SUPERFAMILY SSF55469 265 459 2.22E-38 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 15 460 51.196 T 23-04-2016 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199|UniPathway: UPA00071 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 Pfam PF00881 Nitroreductase family 272 440 9.3E-27 T 23-04-2016 IPR029479 Nitroreductase DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 PANTHER PTHR21712 11 231 1.0E-51 T 23-04-2016 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 Gene3D G3DSA:3.40.109.10 262 458 8.6E-39 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 Gene3D G3DSA:3.30.1330.100 129 218 2.8E-56 T 23-04-2016 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 Gene3D G3DSA:3.30.1330.100 11 62 2.8E-56 T 23-04-2016 DC74_RS17000 4c696fce2c6171f59c719bc64a09981d 460 PANTHER PTHR21712:SF30 11 231 1.0E-51 T 23-04-2016 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 SUPERFAMILY SSF55973 250 401 2.24E-68 T 23-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 SUPERFAMILY SSF55973 119 248 1.18E-45 T 23-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 1.1E-40 T 23-04-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 400 57.222 T 23-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 276 284 - T 23-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 Gene3D G3DSA:3.30.300.10 11 143 1.7E-44 T 23-04-2016 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 250 389 3.6E-68 T 23-04-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 PIRSF PIRSF000497 1 401 4.8E-165 T 23-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 Gene3D G3DSA:3.30.300.10 144 250 4.3E-39 T 23-04-2016 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 PANTHER PTHR11964 3 395 8.2E-250 T 23-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 Gene3D G3DSA:3.30.300.10 261 400 6.5E-70 T 23-04-2016 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 Pfam PF02772 S-adenosylmethionine synthetase, central domain 125 248 1.2E-44 T 23-04-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 399 6.3E-171 T 23-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 SUPERFAMILY SSF55973 3 109 5.89E-45 T 23-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS09400 33449f697d1f0fdc70f27ec158772a0c 402 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 23-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4997 5243 2.7E-90 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1578 1828 2.6E-92 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 5.5E-84 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3301 3549 8.9E-92 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF14765 Polyketide synthase dehydratase 2466 2734 7.8E-60 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF14765 Polyketide synthase dehydratase 4191 4457 3.4E-54 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF14765 Polyketide synthase dehydratase 5891 6160 3.9E-55 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00825 Beta-ketoacyl synthase 4999 5421 3.6E-220 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00825 Beta-ketoacyl synthase 1580 2006 1.6E-229 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00825 Beta-ketoacyl synthase 36 462 8.3E-211 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00825 Beta-ketoacyl synthase 3303 3727 5.1E-218 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6653 6668 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1514 1529 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3234 3249 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF51735 6344 6582 9.16E-49 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF53901 1576 1951 1.25E-105 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF101173 3 34 3.66E-5 T 23-04-2016 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF08659 KR domain 4630 4804 3.9E-57 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF08659 KR domain 2929 3103 5.1E-59 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF08659 KR domain 1204 1382 1.5E-62 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF08659 KR domain 6347 6521 9.9E-59 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF47336 1482 1593 3.93E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1741 1757 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3462 3478 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5156 5172 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF51735 2749 2915 1.26E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.366.10 3825 3950 7.7E-83 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.366.10 2291 2400 4.2E-82 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.366.10 5716 5825 3.5E-81 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.366.10 565 694 2.2E-71 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.366.10 5523 5650 3.5E-81 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.366.10 4016 4125 7.7E-83 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.366.10 763 874 2.2E-71 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.366.10 2102 2225 4.2E-82 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF55048 3955 4016 1.7E-11 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.30.70.250 3955 4015 3.2E-8 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.30.70.250 2230 2290 4.3E-8 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.30.70.250 700 762 2.2E-5 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.30.70.250 5655 5715 6.5E-7 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF00550 Phosphopantetheine attachment site 6628 6694 8.7E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF00550 Phosphopantetheine attachment site 4907 4973 6.1E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF00550 Phosphopantetheine attachment site 3209 3275 3.4E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF00550 Phosphopantetheine attachment site 1489 1555 6.1E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF52151 2105 2225 3.14E-77 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF52151 2284 2397 3.14E-77 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 PANTHER PTHR11712 4097 4788 0.0 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 PANTHER PTHR11712 6273 6704 0.0 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 PANTHER PTHR11712 1137 2761 0.0 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5371 5494 8.2E-16 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 536 3.9E-15 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1956 2067 1.7E-16 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3677 3793 8.4E-13 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1204 1383 1.7E-61 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4630 4806 3.6E-57 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6347 6523 2.9E-59 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2929 3105 8.7E-61 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF52151 3829 3950 1.26E-76 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF52151 4009 4119 1.26E-76 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5532 5823 1.5E-122 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2107 2398 1.5E-130 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 572 872 6.4E-111 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3832 4123 1.1E-126 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF51735 1200 1433 1.46E-49 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF55048 2230 2291 3.01E-11 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.50.720 6345 6555 1.2E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.50.720 2929 3142 1.7E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.50.720 4629 4838 4.2E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.50.720 1204 1385 1.6E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5251 5368 6.4E-44 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 1.1E-43 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1836 1953 1.9E-43 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3557 3674 1.2E-44 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF52151 5529 5650 7.06E-76 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF52151 5709 5817 7.06E-76 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF53901 30 406 3.49E-101 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF51735 6164 6333 3.94E-26 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF51735 4461 4619 3.07E-27 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF47336 4899 5012 1.31E-26 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF47336 6619 6705 7.46E-24 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF51735 990 1190 3.74E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM01294 4906 4973 5.6E-8 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM01294 6627 6694 4.8E-7 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM01294 1488 1555 8.3E-4 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM01294 3208 3275 3.9E-6 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:1.10.1200.10 6623 6699 9.3E-25 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:1.10.1200.10 4903 4977 5.1E-24 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:1.10.1200.10 1485 1559 1.3E-19 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:1.10.1200.10 3203 3279 7.1E-23 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF53901 5396 5410 3.15E-102 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF53901 4995 5364 3.15E-102 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF55048 5655 5716 1.7E-10 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF47336 3201 3316 9.42E-25 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF52151 764 859 5.75E-67 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF52151 569 700 5.75E-67 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 PANTHER PTHR11712:SF242 4097 4788 0.0 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 PANTHER PTHR11712:SF242 6273 6704 0.0 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 PANTHER PTHR11712:SF242 1137 2761 0.0 T 23-04-2016 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF51735 2927 3161 2.89E-47 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.47.10 3303 3561 1.1E-91 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.47.10 1580 1840 6.2E-94 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.47.10 36 296 3.1E-86 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.47.10 4999 5255 2.3E-92 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00826 5891 6052 1.4E-81 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00826 2466 2632 3.5E-85 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00826 4191 4351 1.7E-80 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00823 Phosphopantetheine attachment site 4905 4977 1.2E-33 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00823 Phosphopantetheine attachment site 1487 1559 3.0E-27 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00823 Phosphopantetheine attachment site 6626 6698 7.1E-33 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SMART SM00823 Phosphopantetheine attachment site 3207 3279 2.6E-31 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF55048 699 762 3.01E-11 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF51735 4624 4862 1.22E-49 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 SUPERFAMILY SSF53901 3298 3672 7.0E-103 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF00698 Acyl transferase domain 3831 4141 6.3E-59 T 23-04-2016 IPR014043 Acyl transferase DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF00698 Acyl transferase domain 5531 5841 5.0E-58 T 23-04-2016 IPR014043 Acyl transferase DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF00698 Acyl transferase domain 571 857 1.4E-53 T 23-04-2016 IPR014043 Acyl transferase DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF00698 Acyl transferase domain 2107 2417 5.6E-58 T 23-04-2016 IPR014043 Acyl transferase DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.47.10 297 463 5.6E-65 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.47.10 5256 5421 1.6E-64 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.47.10 3562 3726 3.3E-64 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Gene3D G3DSA:3.40.47.10 1841 2007 8.7E-64 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06815 6f309987f0802c1c04fbc62203177aa3 6786 Pfam PF08990 Erythronolide synthase docking 2 27 1.7E-10 T 23-04-2016 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 DC74_RS03070 76d616b129b13444189d17683c8c6958 251 SMART SM01134 73 233 8.5E-63 T 23-04-2016 DC74_RS03070 76d616b129b13444189d17683c8c6958 251 SMART SM00420 6 58 2.6E-14 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS03070 76d616b129b13444189d17683c8c6958 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 4.5E-14 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS03070 76d616b129b13444189d17683c8c6958 251 SUPERFAMILY SSF100950 77 234 2.85E-26 T 23-04-2016 DC74_RS03070 76d616b129b13444189d17683c8c6958 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.3E-7 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS03070 76d616b129b13444189d17683c8c6958 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.3E-7 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS03070 76d616b129b13444189d17683c8c6958 251 PANTHER PTHR30363 1 251 3.8E-61 T 23-04-2016 DC74_RS03070 76d616b129b13444189d17683c8c6958 251 SUPERFAMILY SSF46785 4 69 2.26E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03070 76d616b129b13444189d17683c8c6958 251 Gene3D G3DSA:3.40.50.1360 84 218 8.9E-9 T 23-04-2016 DC74_RS03070 76d616b129b13444189d17683c8c6958 251 PANTHER PTHR30363:SF13 1 251 3.8E-61 T 23-04-2016 DC74_RS03070 76d616b129b13444189d17683c8c6958 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 23-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 DC74_RS03070 76d616b129b13444189d17683c8c6958 251 Gene3D G3DSA:1.10.10.10 4 83 8.1E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03070 76d616b129b13444189d17683c8c6958 251 Pfam PF00455 DeoR C terminal sensor domain 77 231 1.5E-42 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain DC74_RS02735 599464fc3715149013e36698d1a73929 365 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 5 352 7.3E-94 T 23-04-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 DC74_RS02735 599464fc3715149013e36698d1a73929 365 SUPERFAMILY SSF54593 4 343 3.53E-64 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS02735 599464fc3715149013e36698d1a73929 365 Gene3D G3DSA:3.10.180.10 161 351 3.4E-50 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS02735 599464fc3715149013e36698d1a73929 365 PIRSF PIRSF009283 1 356 3.3E-104 T 23-04-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 DC74_RS02735 599464fc3715149013e36698d1a73929 365 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 108 2.8E-5 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS02735 599464fc3715149013e36698d1a73929 365 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 164 279 3.5E-11 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS02735 599464fc3715149013e36698d1a73929 365 Gene3D G3DSA:3.10.180.10 4 144 1.1E-33 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS02735 599464fc3715149013e36698d1a73929 365 PANTHER PTHR11959 7 351 2.2E-98 T 23-04-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 DC74_RS14670 a118dcac1e131018273c32e8944313be 119 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 52 94 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS14670 a118dcac1e131018273c32e8944313be 119 SUPERFAMILY SSF46689 2 49 1.61E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS14670 a118dcac1e131018273c32e8944313be 119 Gene3D G3DSA:1.10.10.60 53 100 1.3E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS14670 a118dcac1e131018273c32e8944313be 119 Pfam PF12833 Helix-turn-helix domain 21 99 1.2E-26 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS14670 a118dcac1e131018273c32e8944313be 119 SMART SM00342 15 98 3.5E-32 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS14670 a118dcac1e131018273c32e8944313be 119 Gene3D G3DSA:1.10.10.60 2 52 9.1E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS14670 a118dcac1e131018273c32e8944313be 119 PANTHER PTHR11019 3 106 4.8E-30 T 23-04-2016 DC74_RS14670 a118dcac1e131018273c32e8944313be 119 SUPERFAMILY SSF46689 51 102 8.51E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS14670 a118dcac1e131018273c32e8944313be 119 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 82 98 9.6E-6 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS14670 a118dcac1e131018273c32e8944313be 119 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 67 82 9.6E-6 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS22400 00194fd6e479d7b12439839c1a64d98c 122 PANTHER PTHR34068:SF2 14 122 4.8E-33 T 23-04-2016 DC74_RS22400 00194fd6e479d7b12439839c1a64d98c 122 PANTHER PTHR34068 14 122 4.8E-33 T 23-04-2016 DC74_RS22400 00194fd6e479d7b12439839c1a64d98c 122 Pfam PF01906 Putative heavy-metal-binding 16 117 2.3E-33 T 23-04-2016 IPR002765 Uncharacterised protein family UPF0145 DC74_RS22400 00194fd6e479d7b12439839c1a64d98c 122 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 16 118 21.483 T 23-04-2016 IPR002765 Uncharacterised protein family UPF0145 DC74_RS22400 00194fd6e479d7b12439839c1a64d98c 122 Gene3D G3DSA:3.30.110.70 17 117 6.8E-32 T 23-04-2016 IPR002765 Uncharacterised protein family UPF0145 DC74_RS22400 00194fd6e479d7b12439839c1a64d98c 122 SUPERFAMILY SSF117782 17 120 2.22E-31 T 23-04-2016 IPR002765 Uncharacterised protein family UPF0145 DC74_RS07895 1e73f445edfc47495dc9c75ca539101a 262 Gene3D G3DSA:3.40.1410.10 102 244 1.1E-5 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS07895 1e73f445edfc47495dc9c75ca539101a 262 SUPERFAMILY SSF64288 62 252 1.69E-10 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS07895 1e73f445edfc47495dc9c75ca539101a 262 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 74 6.6E-18 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS07895 1e73f445edfc47495dc9c75ca539101a 262 Gene3D G3DSA:1.10.10.10 9 79 1.1E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07895 1e73f445edfc47495dc9c75ca539101a 262 SMART SM00345 15 74 2.2E-19 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS07895 1e73f445edfc47495dc9c75ca539101a 262 SUPERFAMILY SSF46785 8 78 3.59E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07895 1e73f445edfc47495dc9c75ca539101a 262 PANTHER PTHR11751 14 101 5.2E-21 T 23-04-2016 DC74_RS07895 1e73f445edfc47495dc9c75ca539101a 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.1E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS07895 1e73f445edfc47495dc9c75ca539101a 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.1E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 Gene3D G3DSA:2.40.10.10 153 181 4.2E-7 T 23-04-2016 DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 SUPERFAMILY SSF49899 603 784 7.07E-29 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 SUPERFAMILY SSF49899 384 566 3.06E-28 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 SMART SM00020 137 348 4.4E-6 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 Gene3D G3DSA:2.40.10.10 182 351 9.1E-13 T 23-04-2016 DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 Pfam PF00089 Trypsin 152 348 2.9E-18 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 SMART SM00560 855 994 4.9E-23 T 23-04-2016 IPR006558 LamG-like jellyroll fold DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 SMART SM00560 418 557 1.2E-19 T 23-04-2016 IPR006558 LamG-like jellyroll fold DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 SMART SM00560 636 775 1.2E-19 T 23-04-2016 IPR006558 LamG-like jellyroll fold DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 Gene3D G3DSA:2.60.120.200 827 998 7.7E-33 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 Gene3D G3DSA:2.60.120.200 390 564 5.1E-32 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 Gene3D G3DSA:2.60.120.200 608 782 4.3E-32 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 PANTHER PTHR24278 158 360 2.7E-33 T 23-04-2016 DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 SUPERFAMILY SSF50494 152 351 2.24E-23 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 PANTHER PTHR24278:SF22 158 360 2.7E-33 T 23-04-2016 DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 SUPERFAMILY SSF49899 817 998 3.06E-28 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 174 189 1.3E-7 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 296 308 1.3E-7 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 226 240 1.3E-7 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 838 997 2.7E-27 T 23-04-2016 DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 401 558 7.3E-26 T 23-04-2016 DC74_RS40580 bdcfce8941068a306d57825da5aafb76 1005 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 619 776 2.3E-26 T 23-04-2016 DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 SUPERFAMILY SSF81891 177 488 5.49E-69 T 23-04-2016 DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 PANTHER PTHR13734:SF5 38 489 3.1E-115 T 23-04-2016 DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 Gene3D G3DSA:1.10.3090.10 179 365 5.5E-60 T 23-04-2016 DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 Gene3D G3DSA:1.10.3090.10 433 455 5.5E-60 T 23-04-2016 DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 TIGRFAM TIGR00277 HDIG: HDIG domain 278 355 6.7E-18 T 23-04-2016 IPR006675 HDIG domain DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 PANTHER PTHR13734 38 489 3.1E-115 T 23-04-2016 DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 207 267 1.3E-20 T 23-04-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 SUPERFAMILY SSF81301 37 176 9.48E-36 T 23-04-2016 DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 Pfam PF01966 HD domain 281 371 7.6E-16 T 23-04-2016 IPR006674 HD domain DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 29 488 3.8E-245 T 23-04-2016 IPR014065 tRNA adenylyltransferase DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 SMART SM00471 277 445 1.3E-5 T 23-04-2016 IPR003607 HD/PDEase domain DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 Gene3D G3DSA:3.30.460.10 37 178 1.1E-43 T 23-04-2016 DC74_RS20770 c6264d84684fb35a6fb5c07d5fb13b0b 491 Pfam PF01743 Poly A polymerase head domain 57 179 1.8E-31 T 23-04-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 DC74_RS27605 ac143e85a24972f64a1cc84130d60b4e 502 PANTHER PTHR11659 9 501 4.3E-213 T 23-04-2016 IPR017959 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E GO:0016884 DC74_RS27605 ac143e85a24972f64a1cc84130d60b4e 502 Pfam PF02637 GatB domain 353 498 1.4E-40 T 23-04-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 DC74_RS27605 ac143e85a24972f64a1cc84130d60b4e 502 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 15 499 35.791 T 23-04-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 DC74_RS27605 ac143e85a24972f64a1cc84130d60b4e 502 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 15 498 7.0E-139 T 23-04-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 DC74_RS27605 ac143e85a24972f64a1cc84130d60b4e 502 SUPERFAMILY SSF89095 352 498 4.58E-25 T 23-04-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 DC74_RS27605 ac143e85a24972f64a1cc84130d60b4e 502 SMART SM00845 351 498 2.0E-58 T 23-04-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 DC74_RS27605 ac143e85a24972f64a1cc84130d60b4e 502 Gene3D G3DSA:1.10.10.410 443 498 1.7E-4 T 23-04-2016 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal DC74_RS27605 ac143e85a24972f64a1cc84130d60b4e 502 SUPERFAMILY SSF55931 18 320 5.62E-110 T 23-04-2016 DC74_RS27605 ac143e85a24972f64a1cc84130d60b4e 502 Pfam PF02934 GatB/GatE catalytic domain 19 313 2.5E-102 T 23-04-2016 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 DC74_RS27605 ac143e85a24972f64a1cc84130d60b4e 502 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 164 178 - T 23-04-2016 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 DC74_RS27605 ac143e85a24972f64a1cc84130d60b4e 502 PANTHER PTHR11659:SF0 9 501 4.3E-213 T 23-04-2016 DC74_RS12725 a83c26175ba70806251a832cda79d633 338 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 23-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site DC74_RS12725 a83c26175ba70806251a832cda79d633 338 SUPERFAMILY SSF51735 101 297 2.94E-53 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS12725 a83c26175ba70806251a832cda79d633 338 PANTHER PTHR10996 8 322 2.1E-136 T 23-04-2016 DC74_RS12725 a83c26175ba70806251a832cda79d633 338 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 296 2.3E-52 T 23-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DC74_RS12725 a83c26175ba70806251a832cda79d633 338 Gene3D G3DSA:3.40.50.720 118 299 5.5E-56 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS12725 a83c26175ba70806251a832cda79d633 338 Gene3D G3DSA:3.40.50.720 10 117 9.4E-23 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS12725 a83c26175ba70806251a832cda79d633 338 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 324 3.8E-25 T 23-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 DC74_RS12725 a83c26175ba70806251a832cda79d633 338 PANTHER PTHR10996:SF161 8 322 2.1E-136 T 23-04-2016 DC74_RS12725 a83c26175ba70806251a832cda79d633 338 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 146 173 - T 23-04-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 DC74_RS12725 a83c26175ba70806251a832cda79d633 338 SUPERFAMILY SSF52283 2 133 1.42E-30 T 23-04-2016 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 5.3E-17 T 23-04-2016 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 5.3E-17 T 23-04-2016 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 5.3E-17 T 23-04-2016 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 5.3E-17 T 23-04-2016 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 SUPERFAMILY SSF55424 326 418 9.61E-27 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 313 3.7E-65 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 SUPERFAMILY SSF51905 153 323 1.62E-30 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 Gene3D G3DSA:3.50.50.60 4 112 1.8E-35 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 Gene3D G3DSA:3.50.50.60 113 323 1.8E-51 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 SUPERFAMILY SSF51905 7 198 7.17E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 PANTHER PTHR22912 3 398 1.5E-141 T 23-04-2016 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 Pfam PF14759 Reductase C-terminal 333 418 1.8E-16 T 23-04-2016 IPR028202 Reductase, C-terminal DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 3.0E-24 T 23-04-2016 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 3.0E-24 T 23-04-2016 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 3.0E-24 T 23-04-2016 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.0E-24 T 23-04-2016 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 3.0E-24 T 23-04-2016 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 Gene3D G3DSA:3.30.390.30 333 418 3.6E-30 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS39410 675a5bf384255b28ad355125424deb9d 419 PANTHER PTHR22912:SF180 3 398 1.5E-141 T 23-04-2016 DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.3E-16 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 Gene3D G3DSA:3.40.50.2300 58 173 9.9E-56 T 23-04-2016 DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 PANTHER PTHR30146 1 332 3.2E-176 T 23-04-2016 DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 Gene3D G3DSA:1.10.260.40 2 57 5.2E-23 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 Pfam PF13377 Periplasmic binding protein-like domain 167 328 5.0E-40 T 23-04-2016 DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 SUPERFAMILY SSF53822 60 331 1.48E-75 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 SMART SM00354 1 71 7.1E-28 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 SUPERFAMILY SSF47413 1 59 8.13E-17 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 PANTHER PTHR30146:SF59 1 332 3.2E-176 T 23-04-2016 DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.3E-5 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.3E-5 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS11885 7b424e36c421bfd0ec83c0fcf4be3267 334 Gene3D G3DSA:3.40.50.2300 174 307 5.1E-47 T 23-04-2016 DC74_RS02820 4f0308eacc2c274e1354754e1d88d890 611 SMART SM00382 181 320 6.9E-23 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS02820 4f0308eacc2c274e1354754e1d88d890 611 SUPERFAMILY SSF52540 142 388 1.69E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02820 4f0308eacc2c274e1354754e1d88d890 611 Pfam PF06480 FtsH Extracellular 3 86 3.4E-9 T 23-04-2016 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 DC74_RS02820 4f0308eacc2c274e1354754e1d88d890 611 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 185 317 1.1E-42 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS02820 4f0308eacc2c274e1354754e1d88d890 611 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 2 608 33.388 T 23-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 DC74_RS02820 4f0308eacc2c274e1354754e1d88d890 611 ProSitePatterns PS00674 AAA-protein family signature. 288 306 - T 23-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DC74_RS02820 4f0308eacc2c274e1354754e1d88d890 611 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 97 591 4.7E-190 T 23-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 DC74_RS02820 4f0308eacc2c274e1354754e1d88d890 611 Gene3D G3DSA:3.40.50.300 144 326 1.1E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02820 4f0308eacc2c274e1354754e1d88d890 611 PANTHER PTHR23076 1 595 1.0E-250 T 23-04-2016 DC74_RS02820 4f0308eacc2c274e1354754e1d88d890 611 Gene3D G3DSA:1.10.8.60 327 390 1.9E-22 T 23-04-2016 DC74_RS02820 4f0308eacc2c274e1354754e1d88d890 611 SUPERFAMILY SSF140990 402 597 2.09E-56 T 23-04-2016 DC74_RS02820 4f0308eacc2c274e1354754e1d88d890 611 Pfam PF01434 Peptidase family M41 379 589 2.8E-58 T 23-04-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 DC74_RS33245 21b0b44275b220e5e3f2ca64d945e9a9 459 Gene3D G3DSA:3.40.640.10 75 321 2.2E-71 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS33245 21b0b44275b220e5e3f2ca64d945e9a9 459 PANTHER PTHR11986:SF15 4 443 2.6E-270 T 23-04-2016 DC74_RS33245 21b0b44275b220e5e3f2ca64d945e9a9 459 SUPERFAMILY SSF53383 31 436 4.12E-108 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS33245 21b0b44275b220e5e3f2ca64d945e9a9 459 Gene3D G3DSA:3.90.1150.10 322 436 3.0E-33 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS33245 21b0b44275b220e5e3f2ca64d945e9a9 459 Gene3D G3DSA:3.90.1150.10 22 74 3.0E-33 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS33245 21b0b44275b220e5e3f2ca64d945e9a9 459 Pfam PF00202 Aminotransferase class-III 40 434 7.4E-90 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS33245 21b0b44275b220e5e3f2ca64d945e9a9 459 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 232 270 - T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS33245 21b0b44275b220e5e3f2ca64d945e9a9 459 PANTHER PTHR11986 4 443 2.6E-270 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 PANTHER PTHR11712:SF242 1382 2940 0.0 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 PANTHER PTHR11712:SF242 4299 4425 0.0 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 PANTHER PTHR11712:SF242 4525 5605 0.0 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.30.70.250 669 728 2.8E-8 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.30.70.250 8084 8144 1.1E-5 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.30.70.250 2414 2474 9.4E-7 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.30.70.250 6316 6376 9.2E-7 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.30.70.250 9869 9929 5.0E-6 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.30.70.250 4157 4217 3.1E-6 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF55048 4157 4218 1.96E-10 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 5071 5092 - T 23-04-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF55048 2414 2475 1.44E-11 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 405 5.8E-42 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2014 2131 2.2E-44 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 7685 7802 7.3E-45 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3758 3875 9.2E-44 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5890 6007 2.4E-45 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 9467 9584 7.3E-45 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 5251 5492 1.03E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 8813 9027 2.05E-47 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 7059 7295 1.84E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF53901 1754 2127 2.43E-99 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF52151 543 663 1.54E-74 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF52151 722 826 1.54E-74 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF47336 3403 3517 9.42E-24 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 PANTHER PTHR11712 1382 2940 0.0 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 PANTHER PTHR11712 4299 4425 0.0 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 PANTHER PTHR11712 4525 5605 0.0 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 6837 7041 4.72E-23 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF53901 9209 9582 3.99E-101 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:1.10.1200.10 9114 9190 3.2E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:1.10.1200.10 1660 1737 9.7E-26 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:1.10.1200.10 3405 3481 5.2E-23 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:1.10.1200.10 7332 7408 1.8E-20 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:1.10.1200.10 10925 11000 1.9E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:1.10.1200.10 5533 5609 1.4E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF50129 4952 5076 4.09E-28 T 23-04-2016 IPR011032 GroES-like DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF53901 3500 3873 5.92E-99 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF55048 668 729 1.83E-11 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF55048 8084 8145 5.49E-10 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00698 Acyl transferase domain 9744 10055 3.6E-55 T 23-04-2016 IPR014043 Acyl transferase DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00698 Acyl transferase domain 545 855 2.1E-56 T 23-04-2016 IPR014043 Acyl transferase DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00698 Acyl transferase domain 6191 6502 6.0E-54 T 23-04-2016 IPR014043 Acyl transferase DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00698 Acyl transferase domain 7959 8270 1.1E-52 T 23-04-2016 IPR014043 Acyl transferase DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00698 Acyl transferase domain 2290 2585 1.8E-58 T 23-04-2016 IPR014043 Acyl transferase DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00698 Acyl transferase domain 4032 4358 6.1E-55 T 23-04-2016 IPR014043 Acyl transferase DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 10399 10626 4.07E-31 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.366.10 9740 9864 1.0E-79 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.366.10 6377 6487 4.2E-78 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.366.10 729 837 1.2E-76 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.366.10 9930 10040 1.0E-79 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.366.10 8145 8254 2.3E-77 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.366.10 2475 2585 7.3E-82 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.366.10 538 663 1.2E-76 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.366.10 2282 2409 7.3E-82 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.366.10 4024 4152 4.2E-79 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.366.10 7952 8079 2.3E-77 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.366.10 6186 6311 4.2E-78 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.366.10 4218 4342 4.2E-79 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00825 Beta-ketoacyl synthase 37 458 4.4E-210 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00825 Beta-ketoacyl synthase 7431 7855 1.8E-213 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00825 Beta-ketoacyl synthase 9213 9637 1.4E-216 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00825 Beta-ketoacyl synthase 5636 6060 1.5E-212 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00825 Beta-ketoacyl synthase 3504 3928 6.7E-212 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00825 Beta-ketoacyl synthase 1760 2184 1.8E-212 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF52151 6188 6311 9.94E-73 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF52151 6370 6477 9.94E-73 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF52151 7956 8079 5.75E-73 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF52151 8138 8244 5.75E-73 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5256 5436 4.4E-49 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3124 3304 4.4E-49 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10645 10825 1.5E-56 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7058 7234 1.3E-51 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8815 8991 1.1E-53 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1382 1562 3.6E-59 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF47336 9112 9226 4.71E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 2927 3112 1.85E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.90.180.10 4948 5075 9.5E-42 T 23-04-2016 IPR011032 GroES-like DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF08659 KR domain 10645 10823 2.9E-59 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF08659 KR domain 5256 5434 3.0E-55 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF08659 KR domain 7058 7232 3.7E-55 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF08659 KR domain 3124 3302 3.0E-55 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF08659 KR domain 1382 1560 2.7E-59 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF08659 KR domain 8815 8989 3.1E-56 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF47336 7329 7444 9.68E-24 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF52151 9931 10034 5.75E-76 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF52151 9742 9870 5.75E-76 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.50.720 10643 10842 1.4E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF52151 2468 2573 3.66E-76 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF52151 2288 2409 3.66E-76 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF53901 33 396 1.92E-100 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4032 4339 7.7E-124 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 545 836 1.6E-124 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 9744 10038 9.3E-126 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6191 6484 2.0E-121 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7959 8252 2.6E-120 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2291 2582 4.2E-125 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF55048 6316 6377 2.09E-10 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF47336 5531 5648 3.01E-23 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.50.720 1381 1594 2.6E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.50.720 8814 9026 5.8E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.50.720 5255 5468 2.9E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.50.720 7059 7238 2.6E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.50.720 3123 3306 1.6E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00550 Phosphopantetheine attachment site 10935 10996 2.1E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00550 Phosphopantetheine attachment site 5541 5605 5.7E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00550 Phosphopantetheine attachment site 1666 1732 3.7E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00550 Phosphopantetheine attachment site 9121 9186 1.8E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00550 Phosphopantetheine attachment site 3412 3477 6.2E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00550 Phosphopantetheine attachment site 7338 7404 5.6E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7363 7378 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 ProSitePatterns PS00012 Phosphopantetheine attachment site. 9145 9160 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1691 1706 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3436 3451 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5564 5579 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00826 903 1067 3.3E-87 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00826 2650 2812 3.1E-84 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00826 10106 10272 1.5E-72 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00826 8320 8486 6.5E-73 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00826 6551 6716 1.2E-84 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00826 4406 4572 9.1E-84 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 3119 3360 4.57E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 5042 5183 1.42E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF53901 7427 7800 1.26E-101 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 1377 1625 4.35E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5634 5882 7.2E-84 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7429 7677 5.1E-87 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 282 4.5E-86 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 9211 9459 4.9E-87 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3502 3750 8.3E-87 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1758 2006 1.7E-87 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00829 4943 5246 5.3E-175 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF55048 9869 9930 3.01E-10 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF53901 5632 6006 8.25E-102 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 4963 5022 5.3E-6 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF47336 1658 1773 3.93E-27 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF52151 4029 4152 8.37E-75 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF52151 4211 4313 8.37E-75 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF14765 Polyketide synthase dehydratase 6551 6830 1.4E-53 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF14765 Polyketide synthase dehydratase 2650 2920 1.9E-51 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF14765 Polyketide synthase dehydratase 903 1176 1.0E-54 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF14765 Polyketide synthase dehydratase 8320 8606 6.8E-47 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF14765 Polyketide synthase dehydratase 4406 4685 3.1E-56 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF14765 Polyketide synthase dehydratase 10106 10392 4.8E-48 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.47.10 5630 5894 2.5E-88 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.47.10 3500 3762 9.1E-88 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.47.10 9209 9471 4.1E-88 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF00107 Zinc-binding dehydrogenase 5082 5173 2.0E-14 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.50.720 5076 5172 1.5E-17 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM01294 10929 10996 4.0E-6 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM01294 1665 1732 1.3E-9 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM01294 7337 7404 7.0E-7 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM01294 3410 3477 1.3E-9 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM01294 5538 5605 2.6E-7 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM01294 9119 9186 1.7E-6 T 23-04-2016 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 1185 1372 7.48E-26 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3878 3995 2.1E-12 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 6010 6154 9.2E-13 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 9587 9704 6.5E-15 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 7805 7922 9.7E-15 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2134 2254 1.3E-13 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 408 523 9.3E-14 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 8613 8800 3.66E-29 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00823 Phosphopantetheine attachment site 9118 9190 2.3E-29 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00823 Phosphopantetheine attachment site 1664 1736 3.5E-34 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00823 Phosphopantetheine attachment site 7336 7408 2.3E-28 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00823 Phosphopantetheine attachment site 3409 3481 8.4E-32 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00823 Phosphopantetheine attachment site 5537 5609 1.1E-32 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SMART SM00823 Phosphopantetheine attachment site 10928 11000 2.1E-30 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 4691 4921 1.57E-25 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF51735 10644 10858 1.81E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 SUPERFAMILY SSF47336 10921 11002 9.03E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 9372 9388 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1919 1935 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3663 3679 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 7590 7606 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5795 5811 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.47.10 1760 2018 9.2E-88 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.47.10 37 294 6.2E-91 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.47.10 7431 7689 1.1E-87 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.47.10 2019 2182 1.1E-62 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.47.10 3763 3927 1.3E-62 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.47.10 5895 6059 7.4E-64 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.47.10 7690 7854 2.0E-64 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.47.10 295 458 1.4E-62 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38755 05b0baa628bb7fc99578fdd7a82cc206 11084 Gene3D G3DSA:3.40.47.10 9472 9637 2.2E-64 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Pfam PF01571 Aminomethyltransferase folate-binding domain 449 720 2.1E-78 T 23-04-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Gene3D G3DSA:3.30.1360.120 592 697 2.0E-22 T 23-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Gene3D G3DSA:3.30.1360.120 443 530 1.6E-12 T 23-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 PANTHER PTHR13847:SF181 4 468 8.1E-166 T 23-04-2016 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Pfam PF16350 FAD dependent oxidoreductase central domain 391 446 1.6E-19 T 23-04-2016 IPR032503 FAD dependent oxidoreductase, central domain DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Gene3D G3DSA:3.30.70.1400 531 591 7.8E-21 T 23-04-2016 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Gene3D G3DSA:3.50.50.60 146 225 1.6E-58 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Gene3D G3DSA:3.50.50.60 352 432 1.6E-58 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Gene3D G3DSA:3.50.50.60 10 82 1.6E-58 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 SUPERFAMILY SSF101790 744 830 1.54E-21 T 23-04-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Gene3D G3DSA:2.40.30.110 742 816 7.7E-24 T 23-04-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Gene3D G3DSA:3.30.9.10 93 145 1.1E-45 T 23-04-2016 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Gene3D G3DSA:3.30.9.10 226 351 1.1E-45 T 23-04-2016 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 SUPERFAMILY SSF103025 441 735 5.34E-96 T 23-04-2016 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Pfam PF01266 FAD dependent oxidoreductase 12 388 8.6E-48 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 SUPERFAMILY SSF54373 226 351 1.18E-22 T 23-04-2016 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 PANTHER PTHR13847 4 468 8.1E-166 T 23-04-2016 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 726 818 1.1E-14 T 23-04-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 SUPERFAMILY SSF51905 11 226 4.1E-62 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06690 6ecd7e4888b8d781587ad168ec09c1c9 831 SUPERFAMILY SSF51905 352 435 4.1E-62 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS22730 4ead6d7f2d3c8eb827e7f16c1d89ca32 616 SUPERFAMILY SSF52016 426 612 7.69E-62 T 23-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel DC74_RS22730 4ead6d7f2d3c8eb827e7f16c1d89ca32 616 PANTHER PTHR21000:SF11 411 616 0.0 T 23-04-2016 DC74_RS22730 4ead6d7f2d3c8eb827e7f16c1d89ca32 616 Pfam PF00920 Dehydratase family 34 608 5.1E-216 T 23-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS22730 4ead6d7f2d3c8eb827e7f16c1d89ca32 616 PANTHER PTHR21000 3 375 0.0 T 23-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS22730 4ead6d7f2d3c8eb827e7f16c1d89ca32 616 PANTHER PTHR21000 411 616 0.0 T 23-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS22730 4ead6d7f2d3c8eb827e7f16c1d89ca32 616 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 23-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS22730 4ead6d7f2d3c8eb827e7f16c1d89ca32 616 PANTHER PTHR21000:SF11 3 375 0.0 T 23-04-2016 DC74_RS22730 4ead6d7f2d3c8eb827e7f16c1d89ca32 616 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 514 525 - T 23-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS22730 4ead6d7f2d3c8eb827e7f16c1d89ca32 616 SUPERFAMILY SSF143975 4 425 2.35E-132 T 23-04-2016 DC74_RS22730 4ead6d7f2d3c8eb827e7f16c1d89ca32 616 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 611 2.0E-240 T 23-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS22730 4ead6d7f2d3c8eb827e7f16c1d89ca32 616 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 611 45.287 T 23-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS26925 e0ed85acc44e93eb5e46724e22a04d90 188 Pfam PF00430 ATP synthase B/B' CF(0) 23 152 6.4E-29 T 23-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 DC74_RS26925 e0ed85acc44e93eb5e46724e22a04d90 188 Hamap MF_01398 ATP synthase subunit b [atpF]. 5 173 12.069 T 23-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 DC74_RS26925 e0ed85acc44e93eb5e46724e22a04d90 188 SUPERFAMILY SSF81573 79 137 6.8E-11 T 23-04-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain DC74_RS26925 e0ed85acc44e93eb5e46724e22a04d90 188 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 27 173 8.4E-26 T 23-04-2016 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 DC74_RS26925 e0ed85acc44e93eb5e46724e22a04d90 188 Gene3D G3DSA:1.20.5.620 79 138 3.1E-12 T 23-04-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain DC74_RS26925 e0ed85acc44e93eb5e46724e22a04d90 188 PANTHER PTHR33445 2 179 5.9E-44 T 23-04-2016 DC74_RS02150 b193a9a78e8f3a9a49fd02358b78eebf 354 PANTHER PTHR13812 12 348 3.5E-32 T 23-04-2016 DC74_RS02150 b193a9a78e8f3a9a49fd02358b78eebf 354 Gene3D G3DSA:3.30.1780.10 19 158 5.1E-39 T 23-04-2016 IPR023401 Ornithine cyclodeaminase, N-terminal DC74_RS02150 b193a9a78e8f3a9a49fd02358b78eebf 354 PIRSF PIRSF001439 14 346 7.7E-79 T 23-04-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin DC74_RS02150 b193a9a78e8f3a9a49fd02358b78eebf 354 PANTHER PTHR13812:SF19 12 348 3.5E-32 T 23-04-2016 DC74_RS02150 b193a9a78e8f3a9a49fd02358b78eebf 354 SUPERFAMILY SSF51735 19 345 1.78E-65 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02150 b193a9a78e8f3a9a49fd02358b78eebf 354 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 36 335 5.8E-33 T 23-04-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin DC74_RS02150 b193a9a78e8f3a9a49fd02358b78eebf 354 Gene3D G3DSA:3.40.50.720 159 316 9.2E-17 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02150 b193a9a78e8f3a9a49fd02358b78eebf 354 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 20 346 1.3E-127 T 23-04-2016 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 Pfam PF02151 UvrB/uvrC motif 462 494 5.9E-7 T 23-04-2016 IPR001943 UVR domain GO:0005515 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 634 652 2.6E-41 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 663 681 2.6E-41 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 696 710 2.6E-41 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 589 607 2.6E-41 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 SUPERFAMILY SSF52540 534 850 2.05E-77 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 PANTHER PTHR11638 198 860 0.0 T 23-04-2016 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 PANTHER PTHR11638 38 179 0.0 T 23-04-2016 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 762 842 1.1E-23 T 23-04-2016 IPR019489 Clp ATPase, C-terminal DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 SUPERFAMILY SSF81923 50 117 8.37E-7 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 131 174 1.1E-8 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 60 107 2.6E-8 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 246 363 1.4E-11 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 SUPERFAMILY SSF52540 202 474 2.74E-69 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 SMART SM01086 762 851 1.7E-33 T 23-04-2016 IPR019489 Clp ATPase, C-terminal DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 Pfam PF07724 AAA domain (Cdc48 subfamily) 584 756 3.0E-51 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 Gene3D G3DSA:3.40.50.300 203 388 1.2E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 Gene3D G3DSA:3.40.50.300 745 772 3.8E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 Gene3D G3DSA:3.40.50.300 539 711 3.8E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 Gene3D G3DSA:1.10.8.60 773 854 5.3E-28 T 23-04-2016 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 SMART SM00382 241 389 6.8E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 SMART SM00382 585 763 7.5E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 SUPERFAMILY SSF81923 121 196 1.16E-7 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 Gene3D G3DSA:1.10.1780.10 51 173 2.1E-22 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 Gene3D G3DSA:1.10.8.60 390 473 1.1E-33 T 23-04-2016 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 PANTHER PTHR11638:SF108 198 860 0.0 T 23-04-2016 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 PANTHER PTHR11638:SF108 38 179 0.0 T 23-04-2016 DC74_RS06500 0bc34a2a2f73c6d5e91688dfe9e55b08 860 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 619 637 - T 23-04-2016 IPR028299 ClpA/B, conserved site 2 DC74_RS32765 94d769ceb6e809cf1b4f4298efd962bb 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 4.4E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32765 94d769ceb6e809cf1b4f4298efd962bb 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 4.4E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32765 94d769ceb6e809cf1b4f4298efd962bb 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 4.4E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32765 94d769ceb6e809cf1b4f4298efd962bb 151 SUPERFAMILY SSF46785 4 141 4.01E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32765 94d769ceb6e809cf1b4f4298efd962bb 151 SMART SM00347 32 128 6.6E-19 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32765 94d769ceb6e809cf1b4f4298efd962bb 151 Gene3D G3DSA:1.10.10.10 4 141 1.5E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32765 94d769ceb6e809cf1b4f4298efd962bb 151 PANTHER PTHR33164 4 151 3.8E-26 T 23-04-2016 DC74_RS32765 94d769ceb6e809cf1b4f4298efd962bb 151 Pfam PF01047 MarR family 39 94 1.2E-14 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS29045 1da33da67757c51771e97d55978df1db 372 SMART SM00833 257 348 1.0E-10 T 23-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal DC74_RS29045 1da33da67757c51771e97d55978df1db 372 PANTHER PTHR13748:SF10 231 362 3.4E-101 T 23-04-2016 IPR012824 Cobalamin (vitamin B12) biosynthesis CobW GO:0009236 UniPathway: UPA00148 DC74_RS29045 1da33da67757c51771e97d55978df1db 372 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 258 348 1.2E-21 T 23-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal DC74_RS29045 1da33da67757c51771e97d55978df1db 372 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 181 2.5E-45 T 23-04-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain DC74_RS29045 1da33da67757c51771e97d55978df1db 372 SUPERFAMILY SSF90002 258 348 3.4E-17 T 23-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal DC74_RS29045 1da33da67757c51771e97d55978df1db 372 PANTHER PTHR13748:SF10 4 208 3.4E-101 T 23-04-2016 IPR012824 Cobalamin (vitamin B12) biosynthesis CobW GO:0009236 UniPathway: UPA00148 DC74_RS29045 1da33da67757c51771e97d55978df1db 372 PANTHER PTHR13748 231 362 3.4E-101 T 23-04-2016 DC74_RS29045 1da33da67757c51771e97d55978df1db 372 SUPERFAMILY SSF52540 5 176 1.08E-29 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29045 1da33da67757c51771e97d55978df1db 372 Gene3D G3DSA:3.30.1220.10 244 348 4.3E-19 T 23-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal DC74_RS29045 1da33da67757c51771e97d55978df1db 372 PANTHER PTHR13748 4 208 3.4E-101 T 23-04-2016 DC74_RS29045 1da33da67757c51771e97d55978df1db 372 Gene3D G3DSA:3.40.50.300 4 196 4.2E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20210 0ae266930bcb045cd7082a5409493dac 385 SUPERFAMILY SSF52540 1 239 1.6E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20210 0ae266930bcb045cd7082a5409493dac 385 Gene3D G3DSA:3.40.50.300 1 237 2.3E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20210 0ae266930bcb045cd7082a5409493dac 385 SUPERFAMILY SSF54631 258 366 2.24E-10 T 23-04-2016 DC74_RS20210 0ae266930bcb045cd7082a5409493dac 385 PANTHER PTHR24220:SF350 3 258 1.3E-141 T 23-04-2016 DC74_RS20210 0ae266930bcb045cd7082a5409493dac 385 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS20210 0ae266930bcb045cd7082a5409493dac 385 PANTHER PTHR24220 3 258 1.3E-141 T 23-04-2016 DC74_RS20210 0ae266930bcb045cd7082a5409493dac 385 Gene3D G3DSA:3.10.580.10 258 363 2.1E-10 T 23-04-2016 DC74_RS20210 0ae266930bcb045cd7082a5409493dac 385 SMART SM00382 27 214 1.9E-18 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS20210 0ae266930bcb045cd7082a5409493dac 385 Pfam PF00005 ABC transporter 19 164 8.5E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS09495 5c8d52bc1c494492586504ac691ddcc2 363 Gene3D G3DSA:3.40.50.1970 14 176 4.4E-53 T 23-04-2016 DC74_RS09495 5c8d52bc1c494492586504ac691ddcc2 363 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 8 360 36.151 T 23-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 DC74_RS09495 5c8d52bc1c494492586504ac691ddcc2 363 SUPERFAMILY SSF56796 16 357 1.57E-97 T 23-04-2016 DC74_RS09495 5c8d52bc1c494492586504ac691ddcc2 363 PANTHER PTHR21090 1 357 5.2E-136 T 23-04-2016 DC74_RS09495 5c8d52bc1c494492586504ac691ddcc2 363 Gene3D G3DSA:1.20.1090.10 177 355 1.6E-57 T 23-04-2016 DC74_RS09495 5c8d52bc1c494492586504ac691ddcc2 363 Pfam PF01761 3-dehydroquinate synthase 71 327 1.2E-91 T 23-04-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 DC74_RS09495 5c8d52bc1c494492586504ac691ddcc2 363 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 19 346 1.4E-104 T 23-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 DC74_RS09495 5c8d52bc1c494492586504ac691ddcc2 363 PIRSF PIRSF001455 13 359 4.8E-98 T 23-04-2016 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 DC74_RS22450 51fb1111634e41b171102037ed9e4847 371 PANTHER PTHR10907 109 285 7.1E-25 T 23-04-2016 DC74_RS22450 51fb1111634e41b171102037ed9e4847 371 Pfam PF00756 Putative esterase 133 317 2.2E-10 T 23-04-2016 IPR000801 Putative esterase DC74_RS22450 51fb1111634e41b171102037ed9e4847 371 Gene3D G3DSA:3.40.50.1820 112 370 4.7E-35 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS22450 51fb1111634e41b171102037ed9e4847 371 SUPERFAMILY SSF53474 116 370 1.36E-24 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS22450 51fb1111634e41b171102037ed9e4847 371 PANTHER PTHR10907:SF33 109 285 7.1E-25 T 23-04-2016 DC74_RS28890 5eff8ce9539429ac903a1a2e6130cc88 495 Pfam PF13167 GTP-binding GTPase N-terminal 92 180 3.4E-31 T 23-04-2016 IPR025121 GTPase HflX, N-terminal DC74_RS28890 5eff8ce9539429ac903a1a2e6130cc88 495 PANTHER PTHR10229 37 480 1.9E-163 T 23-04-2016 IPR016496 GTPase HflX GO:0005525 DC74_RS28890 5eff8ce9539429ac903a1a2e6130cc88 495 Gene3D G3DSA:3.40.50.300 274 438 3.4E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28890 5eff8ce9539429ac903a1a2e6130cc88 495 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 344 362 1.1E-6 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS28890 5eff8ce9539429ac903a1a2e6130cc88 495 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 277 297 1.1E-6 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS28890 5eff8ce9539429ac903a1a2e6130cc88 495 Pfam PF01926 50S ribosome-binding GTPase 277 395 1.4E-20 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS28890 5eff8ce9539429ac903a1a2e6130cc88 495 Pfam PF16360 GTP-binding GTPase Middle Region 182 269 1.3E-28 T 23-04-2016 IPR032305 GTP-binding protein, middle domain DC74_RS28890 5eff8ce9539429ac903a1a2e6130cc88 495 Hamap MF_00900 GTPase HflX [hflX]. 95 465 47.379 T 23-04-2016 IPR016496 GTPase HflX GO:0005525 DC74_RS28890 5eff8ce9539429ac903a1a2e6130cc88 495 PIRSF PIRSF006809 68 494 2.1E-158 T 23-04-2016 IPR016496 GTPase HflX GO:0005525 DC74_RS28890 5eff8ce9539429ac903a1a2e6130cc88 495 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 76 435 6.8E-130 T 23-04-2016 IPR016496 GTPase HflX GO:0005525 DC74_RS28890 5eff8ce9539429ac903a1a2e6130cc88 495 SUPERFAMILY SSF52540 276 466 2.55E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28890 5eff8ce9539429ac903a1a2e6130cc88 495 PANTHER PTHR10229:SF0 37 480 1.9E-163 T 23-04-2016 DC74_RS18215 b36137fb2b173ad0ec049da899747dfc 425 Pfam PF04909 Amidohydrolase 117 412 1.7E-36 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS18215 b36137fb2b173ad0ec049da899747dfc 425 SUPERFAMILY SSF51556 113 412 3.22E-67 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS18215 b36137fb2b173ad0ec049da899747dfc 425 SUPERFAMILY SSF51556 21 49 3.22E-67 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS18215 b36137fb2b173ad0ec049da899747dfc 425 Gene3D G3DSA:3.20.20.140 22 49 1.5E-62 T 23-04-2016 DC74_RS18215 b36137fb2b173ad0ec049da899747dfc 425 Gene3D G3DSA:3.20.20.140 100 413 1.5E-62 T 23-04-2016 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 Pfam PF14759 Reductase C-terminal 343 414 1.6E-8 T 23-04-2016 IPR028202 Reductase, C-terminal DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 Gene3D G3DSA:3.50.50.60 12 111 8.8E-28 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 SUPERFAMILY SSF55424 335 414 1.26E-18 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 Gene3D G3DSA:3.50.50.60 112 327 2.3E-35 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 PANTHER PTHR22912:SF180 1 388 7.6E-81 T 23-04-2016 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 9.2E-12 T 23-04-2016 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 9.2E-12 T 23-04-2016 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 9.2E-12 T 23-04-2016 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 9.2E-12 T 23-04-2016 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 9.2E-12 T 23-04-2016 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 Gene3D G3DSA:3.30.390.30 343 414 4.4E-17 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 SUPERFAMILY SSF51905 155 327 1.98E-22 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 PANTHER PTHR22912 1 388 7.6E-81 T 23-04-2016 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 320 1.9E-44 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 1.1E-14 T 23-04-2016 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 289 296 1.1E-14 T 23-04-2016 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 257 1.1E-14 T 23-04-2016 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 1.1E-14 T 23-04-2016 DC74_RS04770 03324997a9e6290017ea40c8418d8492 463 SUPERFAMILY SSF51905 14 191 3.46E-36 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03270 f2aff072fc85b3c4e2c19c614a1c53fc 161 Gene3D G3DSA:2.60.40.420 40 137 3.3E-15 T 23-04-2016 IPR008972 Cupredoxin DC74_RS03270 f2aff072fc85b3c4e2c19c614a1c53fc 161 SUPERFAMILY SSF49503 21 134 3.37E-11 T 23-04-2016 IPR008972 Cupredoxin DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 SUPERFAMILY SSF53474 113 169 2.87E-21 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 SUPERFAMILY SSF53474 409 516 2.87E-21 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 SUPERFAMILY SSF53474 204 258 2.87E-21 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 PANTHER PTHR10992:SF878 89 167 2.5E-58 T 23-04-2016 DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 PANTHER PTHR10992:SF878 403 518 2.5E-58 T 23-04-2016 DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 PANTHER PTHR10992:SF878 201 291 2.5E-58 T 23-04-2016 DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 PANTHER PTHR10992 89 167 2.5E-58 T 23-04-2016 DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 PANTHER PTHR10992 403 518 2.5E-58 T 23-04-2016 DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 PANTHER PTHR10992 201 291 2.5E-58 T 23-04-2016 DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 Gene3D G3DSA:3.40.50.1820 202 325 3.8E-56 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 Gene3D G3DSA:3.40.50.1820 84 168 3.8E-56 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 Gene3D G3DSA:3.40.50.1820 396 516 3.8E-56 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08505 02f1629af7adb4eae22e9f681593a3b8 529 Pfam PF00561 alpha/beta hydrolase fold 119 501 4.8E-34 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS10180 fd41f3c12e95ef6571dbd3d264780899 377 SUPERFAMILY SSF50998 27 84 1.54E-15 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS10180 fd41f3c12e95ef6571dbd3d264780899 377 SUPERFAMILY SSF50998 156 337 1.54E-15 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS10180 fd41f3c12e95ef6571dbd3d264780899 377 Pfam PF14269 Arylsulfotransferase (ASST) 105 336 3.5E-17 T 23-04-2016 DC74_RS10180 fd41f3c12e95ef6571dbd3d264780899 377 PANTHER PTHR35340 15 374 1.2E-90 T 23-04-2016 DC74_RS10180 fd41f3c12e95ef6571dbd3d264780899 377 Gene3D G3DSA:2.140.10.10 103 339 4.7E-9 T 23-04-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain DC74_RS10180 fd41f3c12e95ef6571dbd3d264780899 377 PANTHER PTHR35340:SF3 15 374 1.2E-90 T 23-04-2016 DC74_RS33030 19df264fb45ad296e5d28be1870a9773 260 Gene3D G3DSA:1.10.1660.10 9 113 3.9E-20 T 23-04-2016 DC74_RS33030 19df264fb45ad296e5d28be1870a9773 260 PANTHER PTHR30204:SF13 1 236 5.4E-39 T 23-04-2016 DC74_RS33030 19df264fb45ad296e5d28be1870a9773 260 SUPERFAMILY SSF46955 8 93 4.03E-18 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS33030 19df264fb45ad296e5d28be1870a9773 260 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 3.6E-10 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS33030 19df264fb45ad296e5d28be1870a9773 260 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 3.6E-10 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS33030 19df264fb45ad296e5d28be1870a9773 260 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 64 3.6E-10 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS33030 19df264fb45ad296e5d28be1870a9773 260 PANTHER PTHR30204 1 236 5.4E-39 T 23-04-2016 DC74_RS33030 19df264fb45ad296e5d28be1870a9773 260 SMART SM00422 8 77 3.0E-20 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS33030 19df264fb45ad296e5d28be1870a9773 260 Pfam PF13411 MerR HTH family regulatory protein 9 76 4.3E-19 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 9 207 38.063 T 23-04-2016 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 76 92 - T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 SUPERFAMILY SSF53182 10 220 1.83E-67 T 23-04-2016 DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 PANTHER PTHR23402:SF1 9 220 3.0E-60 T 23-04-2016 DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 Gene3D G3DSA:3.40.630.20 9 217 3.5E-65 T 23-04-2016 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 PANTHER PTHR23402 9 220 3.0E-60 T 23-04-2016 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 PIRSF PIRSF015592 8 219 4.2E-78 T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 137 151 - T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 69 81 4.8E-45 T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 169 181 4.8E-45 T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 87 107 4.8E-45 T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 11 34 4.8E-45 T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 139 155 4.8E-45 T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 Pfam PF01470 Pyroglutamyl peptidase 10 208 4.2E-73 T 23-04-2016 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like DC74_RS08275 7e286b5028c90d4ddf0e363ab15cf4ed 221 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 10 218 3.0E-77 T 23-04-2016 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 DC74_RS12490 7668afe0b52c8d4d77aee08a96119176 158 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 122 157 1.6E-12 T 23-04-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 DC74_RS12490 7668afe0b52c8d4d77aee08a96119176 158 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 127 151 - T 23-04-2016 IPR020458 Zinc finger, DksA/TraR C4-type conserved site DC74_RS12490 7668afe0b52c8d4d77aee08a96119176 158 PANTHER PTHR33823 17 158 1.1E-83 T 23-04-2016 DC74_RS12490 7668afe0b52c8d4d77aee08a96119176 158 SUPERFAMILY SSF57716 124 157 1.71E-9 T 23-04-2016 DC74_RS12490 7668afe0b52c8d4d77aee08a96119176 158 SUPERFAMILY SSF109635 25 123 1.83E-10 T 23-04-2016 DC74_RS12490 7668afe0b52c8d4d77aee08a96119176 158 PRINTS PR00618 DksA/TraR zinc finger signature 127 138 2.7E-5 T 23-04-2016 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria DC74_RS12490 7668afe0b52c8d4d77aee08a96119176 158 PRINTS PR00618 DksA/TraR zinc finger signature 139 151 2.7E-5 T 23-04-2016 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria DC74_RS12490 7668afe0b52c8d4d77aee08a96119176 158 PANTHER PTHR33823:SF7 17 158 1.1E-83 T 23-04-2016 DC74_RS16405 1933deb1be890d8bb4445a479bb0b66a 442 SUPERFAMILY SSF54675 13 144 1.88E-43 T 23-04-2016 DC74_RS16405 1933deb1be890d8bb4445a479bb0b66a 442 PIRSF PIRSF000484 9 441 6.9E-98 T 23-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 DC74_RS16405 1933deb1be890d8bb4445a479bb0b66a 442 SUPERFAMILY SSF51690 146 437 2.8E-76 T 23-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 DC74_RS16405 1933deb1be890d8bb4445a479bb0b66a 442 PANTHER PTHR11098:SF8 5 437 4.1E-243 T 23-04-2016 DC74_RS16405 1933deb1be890d8bb4445a479bb0b66a 442 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 16 385 1.0E-125 T 23-04-2016 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 DC74_RS16405 1933deb1be890d8bb4445a479bb0b66a 442 Gene3D G3DSA:3.20.140.10 13 379 2.5E-88 T 23-04-2016 DC74_RS16405 1933deb1be890d8bb4445a479bb0b66a 442 PANTHER PTHR11098 5 437 4.1E-243 T 23-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 DC74_RS36780 b417387c34cb721670b6b437e83a2248 247 Gene3D G3DSA:3.40.50.300 14 214 6.5E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36780 b417387c34cb721670b6b437e83a2248 247 SMART SM00382 40 207 3.2E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS36780 b417387c34cb721670b6b437e83a2248 247 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS36780 b417387c34cb721670b6b437e83a2248 247 PANTHER PTHR24220:SF365 17 224 6.8E-83 T 23-04-2016 IPR017875 Aliphatic sulfonates import ATP-binding protein SsuB GO:0005215|GO:0005524|GO:0005886|GO:0006810 DC74_RS36780 b417387c34cb721670b6b437e83a2248 247 SUPERFAMILY SSF52540 16 216 1.09E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36780 b417387c34cb721670b6b437e83a2248 247 Pfam PF00005 ABC transporter 31 157 2.9E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS36780 b417387c34cb721670b6b437e83a2248 247 PANTHER PTHR24220 17 224 6.8E-83 T 23-04-2016 DC74_RS28865 45f074c6bd37aa7b2b075ccaa697aa60 312 PANTHER PTHR11088 1 288 6.7E-111 T 23-04-2016 DC74_RS28865 45f074c6bd37aa7b2b075ccaa697aa60 312 Pfam PF01715 IPP transferase 43 285 3.4E-74 T 23-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 DC74_RS28865 45f074c6bd37aa7b2b075ccaa697aa60 312 Gene3D G3DSA:1.10.287.890 201 282 2.3E-27 T 23-04-2016 DC74_RS28865 45f074c6bd37aa7b2b075ccaa697aa60 312 Gene3D G3DSA:3.40.50.300 7 176 3.0E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28865 45f074c6bd37aa7b2b075ccaa697aa60 312 SUPERFAMILY SSF52540 10 152 2.17E-15 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28865 45f074c6bd37aa7b2b075ccaa697aa60 312 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 10 307 27.487 T 23-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 DC74_RS28865 45f074c6bd37aa7b2b075ccaa697aa60 312 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 289 4.1E-73 T 23-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 DC74_RS34945 57ad95a38440c06af60e69c7932c8051 363 PANTHER PTHR30146 14 361 3.8E-123 T 23-04-2016 DC74_RS34945 57ad95a38440c06af60e69c7932c8051 363 SMART SM00354 15 85 3.3E-18 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS34945 57ad95a38440c06af60e69c7932c8051 363 SUPERFAMILY SSF47413 14 72 5.04E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS34945 57ad95a38440c06af60e69c7932c8051 363 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 62 9.2E-15 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS34945 57ad95a38440c06af60e69c7932c8051 363 ProSitePatterns PS00356 LacI-type HTH domain signature. 18 36 - T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS34945 57ad95a38440c06af60e69c7932c8051 363 SUPERFAMILY SSF53822 90 341 2.36E-47 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS34945 57ad95a38440c06af60e69c7932c8051 363 Gene3D G3DSA:3.40.50.2300 203 337 1.7E-34 T 23-04-2016 DC74_RS34945 57ad95a38440c06af60e69c7932c8051 363 Gene3D G3DSA:3.40.50.2300 65 202 1.5E-19 T 23-04-2016 DC74_RS34945 57ad95a38440c06af60e69c7932c8051 363 Gene3D G3DSA:1.10.260.40 14 64 7.5E-23 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS34945 57ad95a38440c06af60e69c7932c8051 363 Pfam PF13377 Periplasmic binding protein-like domain 197 356 7.0E-31 T 23-04-2016 DC74_RS34945 57ad95a38440c06af60e69c7932c8051 363 PANTHER PTHR30146:SF45 14 361 3.8E-123 T 23-04-2016 DC74_RS38845 4063c3a324493adb1debe4adb24ec70a 880 SUPERFAMILY SSF51161 722 840 6.1E-20 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS38845 4063c3a324493adb1debe4adb24ec70a 880 SUPERFAMILY SSF47336 30 119 4.06E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38845 4063c3a324493adb1debe4adb24ec70a 880 Gene3D G3DSA:2.160.10.10 755 844 6.0E-27 T 23-04-2016 DC74_RS38845 4063c3a324493adb1debe4adb24ec70a 880 Gene3D G3DSA:2.160.10.10 534 583 6.0E-27 T 23-04-2016 DC74_RS38845 4063c3a324493adb1debe4adb24ec70a 880 Gene3D G3DSA:1.10.1200.10 29 100 4.3E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38845 4063c3a324493adb1debe4adb24ec70a 880 Gene3D G3DSA:2.160.10.10 194 346 2.4E-18 T 23-04-2016 DC74_RS38845 4063c3a324493adb1debe4adb24ec70a 880 SUPERFAMILY SSF51161 229 346 4.85E-15 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS38845 4063c3a324493adb1debe4adb24ec70a 880 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 789 814 0.0019 T 23-04-2016 IPR001451 Hexapeptide repeat DC74_RS38845 4063c3a324493adb1debe4adb24ec70a 880 Pfam PF00550 Phosphopantetheine attachment site 35 96 4.2E-8 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38845 4063c3a324493adb1debe4adb24ec70a 880 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 135 835 2.3E-230 T 23-04-2016 IPR012728 Non-ribosomal peptide synthetase, C-terminal DC74_RS11315 753de7f9f5007d2ea9adebfd0e3344fe 259 PIRSF PIRSF000094 5 259 2.5E-83 T 23-04-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 DC74_RS11315 753de7f9f5007d2ea9adebfd0e3344fe 259 Gene3D G3DSA:3.40.50.720 6 258 1.8E-56 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11315 753de7f9f5007d2ea9adebfd0e3344fe 259 PANTHER PTHR24322:SF317 15 193 7.5E-54 T 23-04-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 DC74_RS11315 753de7f9f5007d2ea9adebfd0e3344fe 259 SUPERFAMILY SSF51735 10 257 9.6E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11315 753de7f9f5007d2ea9adebfd0e3344fe 259 PANTHER PTHR24322 15 193 7.5E-54 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11315 753de7f9f5007d2ea9adebfd0e3344fe 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 255 1.4E-64 T 23-04-2016 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 ProSitePatterns PS01166 RNA polymerases beta chain signature. 868 880 - T 23-04-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Gene3D G3DSA:3.90.1100.10 354 502 1.9E-144 T 23-04-2016 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Gene3D G3DSA:3.90.1100.10 571 625 1.9E-144 T 23-04-2016 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Gene3D G3DSA:3.90.1100.10 30 169 1.9E-144 T 23-04-2016 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 PANTHER PTHR20856 71 933 0.0 T 23-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Gene3D G3DSA:2.40.50.100 627 697 4.7E-26 T 23-04-2016 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 492 1.7E-28 T 23-04-2016 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 PANTHER PTHR20856 957 1129 0.0 T 23-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Gene3D G3DSA:2.40.50.150 734 864 3.9E-56 T 23-04-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 PANTHER PTHR20856:SF20 71 933 0.0 T 23-04-2016 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Pfam PF10385 RNA polymerase beta subunit external 1 domain 502 568 1.7E-25 T 23-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 SUPERFAMILY SSF64484 22 1133 0.0 T 23-04-2016 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 23 1125 12.324 T 23-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Gene3D G3DSA:2.30.150.10 503 568 1.8E-27 T 23-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Pfam PF00562 RNA polymerase Rpb2, domain 6 630 1047 1.6E-155 T 23-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Pfam PF04560 RNA polymerase Rpb2, domain 7 1049 1123 4.0E-27 T 23-04-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 PANTHER PTHR20856 10 49 0.0 T 23-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Gene3D G3DSA:2.40.270.10 865 1025 2.5E-76 T 23-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Gene3D G3DSA:2.40.270.10 698 725 2.5E-76 T 23-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 236 842 0.0 T 23-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Pfam PF04561 RNA polymerase Rpb2, domain 2 169 365 2.5E-29 T 23-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Gene3D G3DSA:3.90.1110.10 171 340 1.1E-68 T 23-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 Pfam PF04563 RNA polymerase beta subunit 70 409 1.3E-21 T 23-04-2016 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 PANTHER PTHR20856:SF20 10 49 0.0 T 23-04-2016 DC74_RS18775 111247c5365290c396b4af25f5464968 1161 PANTHER PTHR20856:SF20 957 1129 0.0 T 23-04-2016 DC74_RS09865 0add2492438dec659472b95faff5cfe3 523 PANTHER PTHR23501:SF65 2 505 9.0E-203 T 23-04-2016 DC74_RS09865 0add2492438dec659472b95faff5cfe3 523 Gene3D G3DSA:1.20.1250.20 4 194 4.1E-30 T 23-04-2016 DC74_RS09865 0add2492438dec659472b95faff5cfe3 523 SUPERFAMILY SSF103473 4 196 3.01E-63 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS09865 0add2492438dec659472b95faff5cfe3 523 SUPERFAMILY SSF103473 468 493 3.01E-63 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS09865 0add2492438dec659472b95faff5cfe3 523 SUPERFAMILY SSF103473 246 417 3.01E-63 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS09865 0add2492438dec659472b95faff5cfe3 523 Pfam PF07690 Major Facilitator Superfamily 16 407 1.7E-51 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS09865 0add2492438dec659472b95faff5cfe3 523 PANTHER PTHR23501 2 505 9.0E-203 T 23-04-2016 DC74_RS09865 0add2492438dec659472b95faff5cfe3 523 Gene3D G3DSA:1.20.1250.20 258 417 1.1E-16 T 23-04-2016 DC74_RS09865 0add2492438dec659472b95faff5cfe3 523 Gene3D G3DSA:1.20.1250.20 468 494 1.1E-16 T 23-04-2016 DC74_RS28010 b810518e3b83f7e93af55f6f5191046a 271 Pfam PF00035 Double-stranded RNA binding motif 177 240 3.4E-17 T 23-04-2016 IPR014720 Double-stranded RNA-binding domain DC74_RS28010 b810518e3b83f7e93af55f6f5191046a 271 PANTHER PTHR11207 15 245 6.0E-90 T 23-04-2016 DC74_RS28010 b810518e3b83f7e93af55f6f5191046a 271 Hamap MF_00104 Ribonuclease 3 [rnc]. 26 239 30.488 T 23-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 DC74_RS28010 b810518e3b83f7e93af55f6f5191046a 271 Pfam PF14622 Ribonuclease-III-like 36 161 2.6E-37 T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 DC74_RS28010 b810518e3b83f7e93af55f6f5191046a 271 Gene3D G3DSA:1.10.1520.10 24 167 4.1E-46 T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 DC74_RS28010 b810518e3b83f7e93af55f6f5191046a 271 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 29 241 4.2E-72 T 23-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 DC74_RS28010 b810518e3b83f7e93af55f6f5191046a 271 ProSitePatterns PS00517 Ribonuclease III family signature. 59 67 - T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 DC74_RS28010 b810518e3b83f7e93af55f6f5191046a 271 SMART SM00358 177 243 4.5E-24 T 23-04-2016 IPR014720 Double-stranded RNA-binding domain DC74_RS28010 b810518e3b83f7e93af55f6f5191046a 271 SUPERFAMILY SSF69065 17 179 3.66E-49 T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 DC74_RS28010 b810518e3b83f7e93af55f6f5191046a 271 Gene3D G3DSA:3.30.160.20 175 242 5.3E-26 T 23-04-2016 IPR014720 Double-stranded RNA-binding domain DC74_RS28010 b810518e3b83f7e93af55f6f5191046a 271 SMART SM00535 37 170 4.9E-60 T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 DC74_RS28010 b810518e3b83f7e93af55f6f5191046a 271 SUPERFAMILY SSF54768 131 242 1.73E-26 T 23-04-2016 DC74_RS03705 c0e2cc342602b690592e516da3c6e010 530 PANTHER PTHR21021:SF15 252 520 1.4E-108 T 23-04-2016 DC74_RS03705 c0e2cc342602b690592e516da3c6e010 530 SMART SM00331 288 511 1.1E-30 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS03705 c0e2cc342602b690592e516da3c6e010 530 SUPERFAMILY SSF55781 124 271 1.72E-10 T 23-04-2016 IPR029016 GAF domain-like DC74_RS03705 c0e2cc342602b690592e516da3c6e010 530 Gene3D G3DSA:3.30.450.40 111 268 1.9E-16 T 23-04-2016 IPR029016 GAF domain-like DC74_RS03705 c0e2cc342602b690592e516da3c6e010 530 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 321 510 1.6E-37 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS03705 c0e2cc342602b690592e516da3c6e010 530 SUPERFAMILY SSF81606 304 509 1.83E-6 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS03705 c0e2cc342602b690592e516da3c6e010 530 SMART SM00065 119 270 0.0042 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS03705 c0e2cc342602b690592e516da3c6e010 530 PANTHER PTHR21021 252 520 1.4E-108 T 23-04-2016 DC74_RS13230 8eb5e28f595f00aa2be74305f62fd450 345 SMART SM00354 9 76 6.6E-18 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS13230 8eb5e28f595f00aa2be74305f62fd450 345 PANTHER PTHR30146:SF4 9 340 6.3E-98 T 23-04-2016 DC74_RS13230 8eb5e28f595f00aa2be74305f62fd450 345 Gene3D G3DSA:1.10.260.40 10 54 5.0E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS13230 8eb5e28f595f00aa2be74305f62fd450 345 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS13230 8eb5e28f595f00aa2be74305f62fd450 345 Gene3D G3DSA:3.40.50.2300 65 177 6.3E-28 T 23-04-2016 DC74_RS13230 8eb5e28f595f00aa2be74305f62fd450 345 Gene3D G3DSA:3.40.50.2300 178 342 1.2E-52 T 23-04-2016 DC74_RS13230 8eb5e28f595f00aa2be74305f62fd450 345 Pfam PF13377 Periplasmic binding protein-like domain 178 340 1.3E-34 T 23-04-2016 DC74_RS13230 8eb5e28f595f00aa2be74305f62fd450 345 SUPERFAMILY SSF47413 10 56 4.45E-10 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS13230 8eb5e28f595f00aa2be74305f62fd450 345 SUPERFAMILY SSF53822 66 342 6.67E-67 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS13230 8eb5e28f595f00aa2be74305f62fd450 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 54 5.1E-12 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS13230 8eb5e28f595f00aa2be74305f62fd450 345 PANTHER PTHR30146 9 340 6.3E-98 T 23-04-2016 DC74_RS32375 32ac0a8d87f9f5c171ec12e0ef635d27 267 Pfam PF04672 S-adenosyl methyltransferase 9 267 8.2E-80 T 23-04-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type DC74_RS32375 32ac0a8d87f9f5c171ec12e0ef635d27 267 SUPERFAMILY SSF53335 17 249 2.88E-38 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS32375 32ac0a8d87f9f5c171ec12e0ef635d27 267 Gene3D G3DSA:3.40.50.150 6 267 1.4E-94 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS32375 32ac0a8d87f9f5c171ec12e0ef635d27 267 PIRSF PIRSF017393 1 267 4.6E-88 T 23-04-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type DC74_RS09820 96eab8942cfa4c728787d3cb809dea5a 285 PIRSF PIRSF002854 2 280 1.0E-95 T 23-04-2016 IPR004872 Lipoprotein NlpA family DC74_RS09820 96eab8942cfa4c728787d3cb809dea5a 285 PANTHER PTHR30429:SF0 4 281 2.7E-116 T 23-04-2016 DC74_RS09820 96eab8942cfa4c728787d3cb809dea5a 285 SUPERFAMILY SSF53850 43 280 6.4E-74 T 23-04-2016 DC74_RS09820 96eab8942cfa4c728787d3cb809dea5a 285 PANTHER PTHR30429 4 281 2.7E-116 T 23-04-2016 IPR004872 Lipoprotein NlpA family DC74_RS09820 96eab8942cfa4c728787d3cb809dea5a 285 Pfam PF03180 NLPA lipoprotein 43 280 7.2E-84 T 23-04-2016 IPR004872 Lipoprotein NlpA family DC74_RS09820 96eab8942cfa4c728787d3cb809dea5a 285 Gene3D G3DSA:3.40.190.10 42 172 1.8E-51 T 23-04-2016 DC74_RS11005 e0364fbe064158a310e93c221b916dac 247 Gene3D G3DSA:3.40.50.300 16 235 8.5E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11005 e0364fbe064158a310e93c221b916dac 247 Hamap MF_00238 Cytidylate kinase [cmk]. 16 238 30.189 T 23-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 DC74_RS11005 e0364fbe064158a310e93c221b916dac 247 TIGRFAM TIGR00017 cmk: cytidylate kinase 16 232 1.3E-57 T 23-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 DC74_RS11005 e0364fbe064158a310e93c221b916dac 247 PANTHER PTHR21299 17 246 5.0E-54 T 23-04-2016 DC74_RS11005 e0364fbe064158a310e93c221b916dac 247 Pfam PF02224 Cytidylate kinase 18 234 8.3E-62 T 23-04-2016 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 DC74_RS11005 e0364fbe064158a310e93c221b916dac 247 SUPERFAMILY SSF52540 16 236 1.47E-33 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00448 1668 1782 7.3E-35 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00388 1313 1381 4.3E-23 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SUPERFAMILY SSF52172 1666 1787 1.17E-35 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 Pfam PF00672 HAMP domain 638 688 2.1E-6 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 Pfam PF00672 HAMP domain 545 596 1.1E-6 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 Pfam PF00672 HAMP domain 269 320 3.0E-8 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SUPERFAMILY SSF47384 1299 1383 9.81E-21 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00304 180 232 2.0E-7 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00304 824 876 5.4E-8 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00304 364 416 2.6E-8 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00304 640 692 6.2E-11 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00304 732 784 1.7E-8 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00304 77 140 0.0061 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00304 456 508 1.2E-9 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00304 272 324 5.1E-11 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00304 916 968 3.7E-9 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00304 1008 1060 5.1E-7 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00304 548 600 3.7E-11 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SUPERFAMILY SSF58104 660 840 1.49E-15 T 23-04-2016 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SUPERFAMILY SSF58104 568 658 8.89E-6 T 23-04-2016 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00065 1084 1238 5.9E-6 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 Gene3D G3DSA:3.40.50.2300 1668 1788 1.5E-38 T 23-04-2016 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1428 1559 2.2E-26 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SUPERFAMILY SSF58104 476 567 3.66E-6 T 23-04-2016 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 Pfam PF13185 GAF domain 1083 1226 2.6E-16 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SUPERFAMILY SSF58104 115 288 1.65E-8 T 23-04-2016 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SUPERFAMILY SSF55874 1370 1559 4.06E-44 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 Gene3D G3DSA:1.10.287.130 1304 1366 6.1E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SUPERFAMILY SSF55781 1047 1228 5.1E-27 T 23-04-2016 IPR029016 GAF domain-like DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 Pfam PF00072 Response regulator receiver domain 1670 1781 8.3E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 Gene3D G3DSA:3.30.450.40 1064 1228 2.2E-21 T 23-04-2016 IPR029016 GAF domain-like DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1486 1500 1.4E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1521 1539 1.4E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1545 1558 1.4E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1504 1514 1.4E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 PANTHER PTHR24423 1292 1460 1.2E-138 T 23-04-2016 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 PANTHER PTHR24423 1476 1789 1.2E-138 T 23-04-2016 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 PANTHER PTHR24423 8 17 1.2E-138 T 23-04-2016 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 PANTHER PTHR24423 450 486 1.2E-138 T 23-04-2016 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 Gene3D G3DSA:3.30.565.10 1367 1559 2.5E-43 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SUPERFAMILY SSF58104 936 1058 4.45E-10 T 23-04-2016 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SMART SM00387 1428 1561 8.2E-36 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SUPERFAMILY SSF58104 292 425 3.92E-10 T 23-04-2016 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1314 1381 9.3E-18 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS28650 13d42ae65c67fd8bc78c7e1c28515fd7 1789 SUPERFAMILY SSF58104 844 933 2.62E-5 T 23-04-2016 DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 Pfam PF13581 Histidine kinase-like ATPase domain 774 881 6.3E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 SUPERFAMILY SSF55781 410 524 4.8E-14 T 23-04-2016 IPR029016 GAF domain-like DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 PANTHER PTHR21021:SF19 467 769 1.3E-60 T 23-04-2016 DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 Gene3D G3DSA:3.30.450.20 229 326 1.9E-8 T 23-04-2016 DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 SMART SM00091 227 292 0.0017 T 23-04-2016 IPR000014 PAS domain DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 Pfam PF13185 GAF domain 402 511 4.3E-7 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 Gene3D G3DSA:3.30.450.40 347 520 1.9E-31 T 23-04-2016 IPR029016 GAF domain-like DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 SUPERFAMILY SSF55874 805 882 3.37E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 SUPERFAMILY SSF81606 555 758 2.28E-11 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 SUPERFAMILY SSF103190 56 183 9.42E-26 T 23-04-2016 IPR029151 Periplasmic sensor domain-like DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 SMART SM00331 541 760 5.0E-42 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 Gene3D G3DSA:3.30.450.20 48 184 2.7E-31 T 23-04-2016 DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 SMART SM00065 347 522 4.0E-4 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 Pfam PF17203 Single cache domain 3 55 183 5.7E-19 T 23-04-2016 IPR033463 Single cache domain 3 DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 567 760 5.8E-51 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 Pfam PF13188 PAS domain 229 290 6.0E-5 T 23-04-2016 IPR000014 PAS domain DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 PANTHER PTHR21021 467 769 1.3E-60 T 23-04-2016 DC74_RS01120 af5e0fa7ce4a9020610981e0e9dd9ecc 890 SUPERFAMILY SSF55785 222 326 1.09E-6 T 23-04-2016 IPR000014 PAS domain DC74_RS38375 5935097341c903cd345431c505698817 837 Gene3D G3DSA:1.10.1200.10 759 824 1.4E-17 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38375 5935097341c903cd345431c505698817 837 Pfam PF00501 AMP-binding enzyme 244 647 2.2E-91 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS38375 5935097341c903cd345431c505698817 837 Gene3D G3DSA:3.40.50.980 399 547 2.2E-43 T 23-04-2016 DC74_RS38375 5935097341c903cd345431c505698817 837 Gene3D G3DSA:3.30.300.30 643 758 4.8E-32 T 23-04-2016 DC74_RS38375 5935097341c903cd345431c505698817 837 SUPERFAMILY SSF56801 233 769 7.59E-144 T 23-04-2016 DC74_RS38375 5935097341c903cd345431c505698817 837 SUPERFAMILY SSF52777 6 208 3.11E-20 T 23-04-2016 DC74_RS38375 5935097341c903cd345431c505698817 837 Pfam PF00550 Phosphopantetheine attachment site 758 819 7.2E-6 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38375 5935097341c903cd345431c505698817 837 Pfam PF13193 AMP-binding enzyme C-terminal domain 656 728 1.1E-9 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS38375 5935097341c903cd345431c505698817 837 Gene3D G3DSA:2.30.38.10 558 637 1.1E-21 T 23-04-2016 DC74_RS38375 5935097341c903cd345431c505698817 837 Gene3D G3DSA:3.40.50.980 237 398 5.4E-48 T 23-04-2016 DC74_RS38375 5935097341c903cd345431c505698817 837 PANTHER PTHR24095:SF173 160 728 6.4E-163 T 23-04-2016 DC74_RS38375 5935097341c903cd345431c505698817 837 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 265 671 1.0E-114 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS38375 5935097341c903cd345431c505698817 837 ProSitePatterns PS00455 Putative AMP-binding domain signature. 389 400 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS38375 5935097341c903cd345431c505698817 837 PANTHER PTHR24095 160 728 6.4E-163 T 23-04-2016 DC74_RS38375 5935097341c903cd345431c505698817 837 SUPERFAMILY SSF47336 749 820 5.63E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS20675 50341f23118ceb947bad4fe4a40ccd4d 378 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 378 96.32 T 23-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 DC74_RS20675 50341f23118ceb947bad4fe4a40ccd4d 378 PANTHER PTHR32182 1 352 3.6E-67 T 23-04-2016 DC74_RS20675 50341f23118ceb947bad4fe4a40ccd4d 378 PANTHER PTHR32182:SF0 1 352 3.6E-67 T 23-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 DC74_RS20675 50341f23118ceb947bad4fe4a40ccd4d 378 ProSitePatterns PS00618 RecF protein signature 2. 319 337 - T 23-04-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 DC74_RS20675 50341f23118ceb947bad4fe4a40ccd4d 378 SUPERFAMILY SSF52540 1 223 8.86E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20675 50341f23118ceb947bad4fe4a40ccd4d 378 SUPERFAMILY SSF52540 255 350 8.86E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20675 50341f23118ceb947bad4fe4a40ccd4d 378 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 351 2.2E-18 T 23-04-2016 IPR003395 RecF/RecN/SMC, N-terminal DC74_RS20675 50341f23118ceb947bad4fe4a40ccd4d 378 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 361 1.8E-126 T 23-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 DC74_RS20675 50341f23118ceb947bad4fe4a40ccd4d 378 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 23-04-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 DC74_RS20675 50341f23118ceb947bad4fe4a40ccd4d 378 Gene3D G3DSA:3.40.50.300 245 350 2.3E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20675 50341f23118ceb947bad4fe4a40ccd4d 378 Gene3D G3DSA:3.40.50.300 1 167 2.3E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22100 bc6dd85bd9725a672f80a6f96ae12f9b 329 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 223 2.2E-11 T 23-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DC74_RS22100 bc6dd85bd9725a672f80a6f96ae12f9b 329 Gene3D G3DSA:3.40.50.300 1 251 8.4E-30 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22100 bc6dd85bd9725a672f80a6f96ae12f9b 329 PANTHER PTHR13696 1 284 2.2E-49 T 23-04-2016 DC74_RS22100 bc6dd85bd9725a672f80a6f96ae12f9b 329 PANTHER PTHR13696:SF64 1 284 2.2E-49 T 23-04-2016 DC74_RS22100 bc6dd85bd9725a672f80a6f96ae12f9b 329 SUPERFAMILY SSF52540 89 244 2.68E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22100 bc6dd85bd9725a672f80a6f96ae12f9b 329 SUPERFAMILY SSF52540 1 51 2.68E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36580 d7f5f43b44d3a436106ec4e7aca1a1b8 357 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 199 341 5.5E-12 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS36580 d7f5f43b44d3a436106ec4e7aca1a1b8 357 PANTHER PTHR10909 100 311 3.4E-16 T 23-04-2016 DC74_RS36580 d7f5f43b44d3a436106ec4e7aca1a1b8 357 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 92 185 1.3E-16 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS36580 d7f5f43b44d3a436106ec4e7aca1a1b8 357 SUPERFAMILY SSF47203 199 341 3.06E-10 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS36580 d7f5f43b44d3a436106ec4e7aca1a1b8 357 SUPERFAMILY SSF56645 8 202 1.83E-29 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS36580 d7f5f43b44d3a436106ec4e7aca1a1b8 357 Gene3D G3DSA:2.40.110.10 92 186 3.5E-21 T 23-04-2016 DC74_RS36580 d7f5f43b44d3a436106ec4e7aca1a1b8 357 Gene3D G3DSA:1.20.140.10 187 341 2.7E-18 T 23-04-2016 DC74_RS11410 2d7f3c959b6a3164aa96bc3991145076 328 PANTHER PTHR30231 19 288 6.8E-49 T 23-04-2016 DC74_RS11410 2d7f3c959b6a3164aa96bc3991145076 328 Gene3D G3DSA:3.30.420.10 21 183 3.4E-44 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS11410 2d7f3c959b6a3164aa96bc3991145076 328 Gene3D G3DSA:3.40.50.10190 242 319 2.2E-10 T 23-04-2016 IPR001357 BRCT domain DC74_RS11410 2d7f3c959b6a3164aa96bc3991145076 328 PANTHER PTHR30231:SF4 19 288 6.8E-49 T 23-04-2016 DC74_RS11410 2d7f3c959b6a3164aa96bc3991145076 328 Pfam PF00929 Exonuclease 24 176 1.6E-20 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III DC74_RS11410 2d7f3c959b6a3164aa96bc3991145076 328 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 22 181 2.6E-23 T 23-04-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS11410 2d7f3c959b6a3164aa96bc3991145076 328 SUPERFAMILY SSF52113 240 318 5.89E-10 T 23-04-2016 IPR001357 BRCT domain DC74_RS11410 2d7f3c959b6a3164aa96bc3991145076 328 SMART SM00479 21 185 1.8E-32 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III DC74_RS11410 2d7f3c959b6a3164aa96bc3991145076 328 SUPERFAMILY SSF53098 20 185 1.37E-40 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS22850 9b8262f6356c3c79fcc2dab1fc94196c 967 Pfam PF00202 Aminotransferase class-III 26 510 1.2E-57 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS22850 9b8262f6356c3c79fcc2dab1fc94196c 967 Gene3D G3DSA:3.40.640.10 65 139 5.5E-57 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS22850 9b8262f6356c3c79fcc2dab1fc94196c 967 Gene3D G3DSA:3.40.640.10 205 399 5.5E-57 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS22850 9b8262f6356c3c79fcc2dab1fc94196c 967 SUPERFAMILY SSF53383 24 135 2.63E-69 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS22850 9b8262f6356c3c79fcc2dab1fc94196c 967 SUPERFAMILY SSF53383 201 514 2.63E-69 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS22850 9b8262f6356c3c79fcc2dab1fc94196c 967 PANTHER PTHR11986:SF79 25 140 1.5E-108 T 23-04-2016 DC74_RS22850 9b8262f6356c3c79fcc2dab1fc94196c 967 PANTHER PTHR11986:SF79 198 522 1.5E-108 T 23-04-2016 DC74_RS22850 9b8262f6356c3c79fcc2dab1fc94196c 967 PANTHER PTHR11986 25 140 1.5E-108 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS22850 9b8262f6356c3c79fcc2dab1fc94196c 967 PANTHER PTHR11986 198 522 1.5E-108 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS22850 9b8262f6356c3c79fcc2dab1fc94196c 967 Gene3D G3DSA:3.90.1150.10 25 64 1.8E-17 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS22850 9b8262f6356c3c79fcc2dab1fc94196c 967 Gene3D G3DSA:3.90.1150.10 404 514 1.8E-17 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS08705 6486746367a9b0a6c796c942cd773f10 165 Pfam PF00293 NUDIX domain 22 138 4.2E-20 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS08705 6486746367a9b0a6c796c942cd773f10 165 Gene3D G3DSA:3.90.79.10 22 143 4.3E-28 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS08705 6486746367a9b0a6c796c942cd773f10 165 PANTHER PTHR22769:SF17 22 132 1.6E-28 T 23-04-2016 DC74_RS08705 6486746367a9b0a6c796c942cd773f10 165 PANTHER PTHR22769 22 132 1.6E-28 T 23-04-2016 DC74_RS08705 6486746367a9b0a6c796c942cd773f10 165 SUPERFAMILY SSF55811 11 134 1.62E-29 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS32345 27bd4161eb6138575c1ed7e8cac5c9fe 350 PANTHER PTHR11732:SF217 1 333 1.8E-113 T 23-04-2016 DC74_RS32345 27bd4161eb6138575c1ed7e8cac5c9fe 350 PANTHER PTHR11732 1 333 1.8E-113 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS32345 27bd4161eb6138575c1ed7e8cac5c9fe 350 Pfam PF00248 Aldo/keto reductase family 16 307 3.3E-61 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS32345 27bd4161eb6138575c1ed7e8cac5c9fe 350 Gene3D G3DSA:3.20.20.100 9 311 2.4E-83 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS32345 27bd4161eb6138575c1ed7e8cac5c9fe 350 SUPERFAMILY SSF51430 1 309 8.51E-85 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS24715 b1a8164b12f39d4f2aac07d7deb049c0 425 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 225 241 - T 23-04-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS24715 b1a8164b12f39d4f2aac07d7deb049c0 425 PIRSF PIRSF000412 3 422 5.0E-161 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS24715 b1a8164b12f39d4f2aac07d7deb049c0 425 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 10 420 48.991 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS24715 b1a8164b12f39d4f2aac07d7deb049c0 425 Gene3D G3DSA:3.90.1150.10 287 420 6.6E-52 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS24715 b1a8164b12f39d4f2aac07d7deb049c0 425 Gene3D G3DSA:3.40.640.10 40 286 3.2E-91 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS24715 b1a8164b12f39d4f2aac07d7deb049c0 425 Pfam PF00464 Serine hydroxymethyltransferase 12 387 9.3E-152 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS24715 b1a8164b12f39d4f2aac07d7deb049c0 425 PANTHER PTHR11680 11 425 2.4E-217 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS24715 b1a8164b12f39d4f2aac07d7deb049c0 425 SUPERFAMILY SSF53383 11 420 1.03E-161 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS32600 4c707f3382d2f9f48ffb15767610bc27 376 SMART SM01240 3 358 2.4E-156 T 23-04-2016 DC74_RS32600 4c707f3382d2f9f48ffb15767610bc27 376 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 4 358 2.3E-118 T 23-04-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 DC74_RS32600 4c707f3382d2f9f48ffb15767610bc27 376 Gene3D G3DSA:3.20.20.70 2 366 1.1E-107 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS32600 4c707f3382d2f9f48ffb15767610bc27 376 PANTHER PTHR11911 183 358 6.5E-68 T 23-04-2016 DC74_RS32600 4c707f3382d2f9f48ffb15767610bc27 376 PANTHER PTHR11911:SF6 94 165 6.5E-68 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 DC74_RS32600 4c707f3382d2f9f48ffb15767610bc27 376 SUPERFAMILY SSF51412 2 361 5.49E-105 T 23-04-2016 DC74_RS32600 4c707f3382d2f9f48ffb15767610bc27 376 PANTHER PTHR11911:SF6 183 358 6.5E-68 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 DC74_RS32600 4c707f3382d2f9f48ffb15767610bc27 376 PANTHER PTHR11911 94 165 6.5E-68 T 23-04-2016 DC74_RS11735 f9d6e7dfa428ab58afc727cd57228fac 473 PANTHER PTHR30508 17 473 3.5E-242 T 23-04-2016 DC74_RS11735 f9d6e7dfa428ab58afc727cd57228fac 473 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 17 464 2.7E-219 T 23-04-2016 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 DC74_RS11735 f9d6e7dfa428ab58afc727cd57228fac 473 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 6.9E-75 T 23-04-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 DC74_RS11735 f9d6e7dfa428ab58afc727cd57228fac 473 PANTHER PTHR30508:SF1 17 473 3.5E-242 T 23-04-2016 DC74_RS11735 f9d6e7dfa428ab58afc727cd57228fac 473 SUPERFAMILY SSF101960 40 470 5.89E-139 T 23-04-2016 DC74_RS25870 e30fe5f866a6fe20eec5ecf374f45aae 330 Pfam PF02585 GlcNAc-PI de-N-acetylase 26 176 9.4E-25 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS25870 e30fe5f866a6fe20eec5ecf374f45aae 330 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 25 310 41.214 T 23-04-2016 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 DC74_RS25870 e30fe5f866a6fe20eec5ecf374f45aae 330 PANTHER PTHR12993:SF13 21 315 2.2E-68 T 23-04-2016 DC74_RS25870 e30fe5f866a6fe20eec5ecf374f45aae 330 SUPERFAMILY SSF102588 23 310 2.35E-67 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS25870 e30fe5f866a6fe20eec5ecf374f45aae 330 PANTHER PTHR12993 21 315 2.2E-68 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS25870 e30fe5f866a6fe20eec5ecf374f45aae 330 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 26 310 5.0E-121 T 23-04-2016 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 DC74_RS25870 e30fe5f866a6fe20eec5ecf374f45aae 330 Gene3D G3DSA:3.40.50.10320 22 314 2.4E-88 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS18955 cc2ff41a8982bbcb1ef2cd74dc2b60e5 456 SUPERFAMILY SSF55874 331 454 1.95E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS18955 cc2ff41a8982bbcb1ef2cd74dc2b60e5 456 Pfam PF07730 Histidine kinase 254 318 7.5E-13 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS18955 cc2ff41a8982bbcb1ef2cd74dc2b60e5 456 Pfam PF13796 Putative sensor 38 226 1.2E-40 T 23-04-2016 IPR025828 Putative sensor domain DC74_RS18955 cc2ff41a8982bbcb1ef2cd74dc2b60e5 456 PANTHER PTHR24421 113 455 2.6E-150 T 23-04-2016 DC74_RS18955 cc2ff41a8982bbcb1ef2cd74dc2b60e5 456 PANTHER PTHR24421:SF13 113 455 2.6E-150 T 23-04-2016 DC74_RS10605 a9ef2f2845dcd4d66d03f99abe7a6a61 404 Gene3D G3DSA:1.10.540.10 1 132 3.0E-34 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS10605 a9ef2f2845dcd4d66d03f99abe7a6a61 404 SUPERFAMILY SSF47203 247 403 4.35E-42 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS10605 a9ef2f2845dcd4d66d03f99abe7a6a61 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 237 1.3E-21 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS10605 a9ef2f2845dcd4d66d03f99abe7a6a61 404 Gene3D G3DSA:2.40.110.10 133 238 2.0E-40 T 23-04-2016 DC74_RS10605 a9ef2f2845dcd4d66d03f99abe7a6a61 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 130 2.1E-15 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS10605 a9ef2f2845dcd4d66d03f99abe7a6a61 404 Gene3D G3DSA:1.20.140.10 239 402 5.0E-47 T 23-04-2016 DC74_RS10605 a9ef2f2845dcd4d66d03f99abe7a6a61 404 PANTHER PTHR10909 1 403 3.6E-205 T 23-04-2016 DC74_RS10605 a9ef2f2845dcd4d66d03f99abe7a6a61 404 SUPERFAMILY SSF56645 1 262 1.7E-65 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS10605 a9ef2f2845dcd4d66d03f99abe7a6a61 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 399 1.9E-34 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS10605 a9ef2f2845dcd4d66d03f99abe7a6a61 404 PANTHER PTHR10909:SF195 1 403 3.6E-205 T 23-04-2016 DC74_RS38425 22c43c467dec2eaa26161cdd8cc44a21 192 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 48 141 1.9E-19 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS38425 22c43c467dec2eaa26161cdd8cc44a21 192 PANTHER PTHR30212:SF4 27 182 5.3E-35 T 23-04-2016 DC74_RS38425 22c43c467dec2eaa26161cdd8cc44a21 192 PANTHER PTHR30212 27 182 5.3E-35 T 23-04-2016 DC74_RS38425 22c43c467dec2eaa26161cdd8cc44a21 192 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 27 188 9.3E-66 T 23-04-2016 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent DC74_RS38425 22c43c467dec2eaa26161cdd8cc44a21 192 SUPERFAMILY SSF50475 48 168 7.66E-20 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS38425 22c43c467dec2eaa26161cdd8cc44a21 192 Gene3D G3DSA:2.30.110.10 40 166 2.3E-30 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS33285 e0e5ca54b9ae2b28ef2f62b0381b4356 466 SMART SM00729 54 276 5.1E-36 T 23-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 DC74_RS33285 e0e5ca54b9ae2b28ef2f62b0381b4356 466 Pfam PF04055 Radical SAM superfamily 60 231 4.1E-14 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS33285 e0e5ca54b9ae2b28ef2f62b0381b4356 466 Gene3D G3DSA:3.80.30.20 55 271 1.6E-22 T 23-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe DC74_RS33285 e0e5ca54b9ae2b28ef2f62b0381b4356 466 SUPERFAMILY SSF102114 19 452 3.14E-72 T 23-04-2016 DC74_RS33285 e0e5ca54b9ae2b28ef2f62b0381b4356 466 PANTHER PTHR13932 24 462 6.9E-70 T 23-04-2016 DC74_RS20220 c1d27171083de715eaa31541c340170b 224 Gene3D G3DSA:1.10.3720.10 8 213 3.5E-24 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS20220 c1d27171083de715eaa31541c340170b 224 SUPERFAMILY SSF161098 22 206 1.57E-32 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS20220 c1d27171083de715eaa31541c340170b 224 PANTHER PTHR30177:SF4 16 218 8.2E-44 T 23-04-2016 DC74_RS20220 c1d27171083de715eaa31541c340170b 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 214 8.5E-23 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS20220 c1d27171083de715eaa31541c340170b 224 PANTHER PTHR30177 16 218 8.2E-44 T 23-04-2016 DC74_RS33225 a40b981aa4421ae90d55c8bfb2295262 371 PANTHER PTHR12001 44 371 3.7E-183 T 23-04-2016 IPR017446 Polyprenyl synthetase-related DC74_RS33225 a40b981aa4421ae90d55c8bfb2295262 371 Pfam PF00348 Polyprenyl synthetase 77 308 7.3E-51 T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 DC74_RS33225 a40b981aa4421ae90d55c8bfb2295262 371 SUPERFAMILY SSF48576 49 369 6.4E-73 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS33225 a40b981aa4421ae90d55c8bfb2295262 371 Gene3D G3DSA:1.10.600.10 77 370 2.4E-79 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS33225 a40b981aa4421ae90d55c8bfb2295262 371 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 116 130 - T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 DC74_RS33225 a40b981aa4421ae90d55c8bfb2295262 371 PANTHER PTHR12001:SF51 44 371 3.7E-183 T 23-04-2016 DC74_RS09930 7d6007cd69514494acd319217cf4bde3 275 SUPERFAMILY SSF51735 1 273 4.69E-53 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09930 7d6007cd69514494acd319217cf4bde3 275 Pfam PF04321 RmlD substrate binding domain 1 269 1.5E-40 T 23-04-2016 IPR029903 RmlD-like substrate binding domain DC74_RS09930 7d6007cd69514494acd319217cf4bde3 275 PANTHER PTHR10491 1 273 1.1E-96 T 23-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family DC74_RS09930 7d6007cd69514494acd319217cf4bde3 275 PANTHER PTHR10491:SF6 1 273 1.1E-96 T 23-04-2016 DC74_RS09930 7d6007cd69514494acd319217cf4bde3 275 Gene3D G3DSA:3.40.50.720 1 218 7.0E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09740 3276eb01c7e45ee8ccd627a2f9f235ab 276 PANTHER PTHR23091 99 267 7.3E-17 T 23-04-2016 DC74_RS09740 3276eb01c7e45ee8ccd627a2f9f235ab 276 SUPERFAMILY SSF55729 128 273 3.31E-20 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS09740 3276eb01c7e45ee8ccd627a2f9f235ab 276 Gene3D G3DSA:3.40.630.30 129 270 1.3E-20 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS09740 3276eb01c7e45ee8ccd627a2f9f235ab 276 Pfam PF00583 Acetyltransferase (GNAT) family 193 265 2.3E-12 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS09740 3276eb01c7e45ee8ccd627a2f9f235ab 276 Pfam PF00583 Acetyltransferase (GNAT) family 32 105 2.0E-5 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS09740 3276eb01c7e45ee8ccd627a2f9f235ab 276 SUPERFAMILY SSF55729 20 109 1.39E-10 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS09740 3276eb01c7e45ee8ccd627a2f9f235ab 276 Gene3D G3DSA:3.40.630.30 25 110 1.6E-11 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS09740 3276eb01c7e45ee8ccd627a2f9f235ab 276 PANTHER PTHR23091:SF71 99 267 7.3E-17 T 23-04-2016 DC74_RS17560 baeab5f9a335c14ef9c65454b4fad245 348 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 154 171 - T 23-04-2016 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17560 baeab5f9a335c14ef9c65454b4fad245 348 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 103 345 3.9E-40 T 23-04-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17560 baeab5f9a335c14ef9c65454b4fad245 348 PIRSF PIRSF000808 34 347 1.3E-105 T 23-04-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17560 baeab5f9a335c14ef9c65454b4fad245 348 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 102 178 9.4E-27 T 23-04-2016 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17560 baeab5f9a335c14ef9c65454b4fad245 348 Gene3D G3DSA:3.30.428.10 180 345 1.8E-50 T 23-04-2016 IPR011146 HIT-like domain GO:0003824 DC74_RS17560 baeab5f9a335c14ef9c65454b4fad245 348 Gene3D G3DSA:3.30.428.10 67 178 9.4E-34 T 23-04-2016 IPR011146 HIT-like domain GO:0003824 DC74_RS17560 baeab5f9a335c14ef9c65454b4fad245 348 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 195 342 5.5E-14 T 23-04-2016 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17560 baeab5f9a335c14ef9c65454b4fad245 348 PANTHER PTHR11943 25 347 8.1E-114 T 23-04-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS17560 baeab5f9a335c14ef9c65454b4fad245 348 SUPERFAMILY SSF54197 182 345 7.83E-36 T 23-04-2016 IPR011146 HIT-like domain GO:0003824 DC74_RS17560 baeab5f9a335c14ef9c65454b4fad245 348 SUPERFAMILY SSF54197 38 179 3.56E-48 T 23-04-2016 IPR011146 HIT-like domain GO:0003824 DC74_RS11650 9b049f9cbe75bd6fa437b2f3dd321894 270 PANTHER PTHR10366:SF476 6 217 2.0E-60 T 23-04-2016 DC74_RS11650 9b049f9cbe75bd6fa437b2f3dd321894 270 Gene3D G3DSA:3.40.50.720 4 215 1.7E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11650 9b049f9cbe75bd6fa437b2f3dd321894 270 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 167 6.9E-19 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS11650 9b049f9cbe75bd6fa437b2f3dd321894 270 SUPERFAMILY SSF51735 5 235 1.13E-42 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11650 9b049f9cbe75bd6fa437b2f3dd321894 270 PANTHER PTHR10366 6 217 2.0E-60 T 23-04-2016 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 115 127 1.2E-11 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 247 265 1.2E-11 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 154 1.2E-11 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 93 101 1.2E-11 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 Gene3D G3DSA:3.50.50.60 236 279 6.6E-28 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 Gene3D G3DSA:3.50.50.60 1 117 6.6E-28 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 PANTHER PTHR22912 1 282 1.3E-95 T 23-04-2016 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 Gene3D G3DSA:3.50.50.60 118 216 4.7E-39 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 SUPERFAMILY SSF51905 1 281 5.94E-37 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 9.0E-11 T 23-04-2016 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 92 110 9.0E-11 T 23-04-2016 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 259 9.0E-11 T 23-04-2016 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 271 3.7E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07995 9bb6c9f1aed4351608a6c4f46637bcf6 303 PANTHER PTHR22912:SF159 1 282 1.3E-95 T 23-04-2016 DC74_RS30835 39e95a28a6cfeb0268eb969f3009e21e 369 SUPERFAMILY SSF53850 51 283 8.39E-40 T 23-04-2016 DC74_RS30835 39e95a28a6cfeb0268eb969f3009e21e 369 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 52 349 9.3E-61 T 23-04-2016 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 DC74_RS30835 39e95a28a6cfeb0268eb969f3009e21e 369 PANTHER PTHR30024:SF1 50 289 8.6E-45 T 23-04-2016 DC74_RS30835 39e95a28a6cfeb0268eb969f3009e21e 369 Pfam PF13379 NMT1-like family 50 280 4.6E-28 T 23-04-2016 DC74_RS30835 39e95a28a6cfeb0268eb969f3009e21e 369 PANTHER PTHR30024 50 289 8.6E-45 T 23-04-2016 DC74_RS30835 39e95a28a6cfeb0268eb969f3009e21e 369 Gene3D G3DSA:3.40.190.10 138 268 4.6E-19 T 23-04-2016 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 Gene3D G3DSA:1.10.630.10 11 390 1.2E-114 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 332 341 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 Pfam PF00067 Cytochrome P450 193 360 1.6E-26 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 SUPERFAMILY SSF48264 13 391 8.12E-94 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00359 B-class P450 signature 339 350 1.3E-49 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00359 B-class P450 signature 128 144 1.3E-49 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00359 B-class P450 signature 181 203 1.3E-49 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00359 B-class P450 signature 330 339 1.3E-49 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00359 B-class P450 signature 309 324 1.3E-49 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00359 B-class P450 signature 82 93 1.3E-49 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00359 B-class P450 signature 281 308 1.3E-49 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00359 B-class P450 signature 263 274 1.3E-49 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00359 B-class P450 signature 145 160 1.3E-49 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00385 P450 superfamily signature 339 350 3.8E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00385 P450 superfamily signature 263 274 3.8E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00385 P450 superfamily signature 330 339 3.8E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PRINTS PR00385 P450 superfamily signature 228 245 3.8E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS22810 3e32a42b263296d85dbcb2814f6d128c 395 PANTHER PTHR11712 14 390 3.0E-87 T 23-04-2016 DC74_RS04630 6e23c2f6311e13594ba29c25ac3d69a0 69 PANTHER PTHR38444 1 68 4.4E-18 T 23-04-2016 DC74_RS04630 6e23c2f6311e13594ba29c25ac3d69a0 69 Gene3D G3DSA:3.90.820.10 9 66 5.1E-27 T 23-04-2016 DC74_RS04630 6e23c2f6311e13594ba29c25ac3d69a0 69 Pfam PF03621 MbtH-like protein 3 51 2.5E-19 T 23-04-2016 IPR005153 MbtH-like protein DC74_RS04630 6e23c2f6311e13594ba29c25ac3d69a0 69 SUPERFAMILY SSF160582 4 66 1.44E-23 T 23-04-2016 DC74_RS04630 6e23c2f6311e13594ba29c25ac3d69a0 69 SMART SM00923 1 51 8.8E-19 T 23-04-2016 IPR005153 MbtH-like protein DC74_RS04630 6e23c2f6311e13594ba29c25ac3d69a0 69 PANTHER PTHR38444:SF1 1 68 4.4E-18 T 23-04-2016 DC74_RS08930 992a18b9e7baf2adb2e3efcea9e465a6 274 Gene3D G3DSA:3.40.50.720 30 269 8.6E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS08930 992a18b9e7baf2adb2e3efcea9e465a6 274 Pfam PF00106 short chain dehydrogenase 36 205 5.4E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08930 992a18b9e7baf2adb2e3efcea9e465a6 274 PANTHER PTHR24322 39 170 7.8E-16 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08930 992a18b9e7baf2adb2e3efcea9e465a6 274 PANTHER PTHR24322 186 201 7.8E-16 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08930 992a18b9e7baf2adb2e3efcea9e465a6 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 123 9.8E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08930 992a18b9e7baf2adb2e3efcea9e465a6 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 176 9.8E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08930 992a18b9e7baf2adb2e3efcea9e465a6 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 36 53 9.8E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08930 992a18b9e7baf2adb2e3efcea9e465a6 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 205 9.8E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08930 992a18b9e7baf2adb2e3efcea9e465a6 274 SUPERFAMILY SSF51735 31 271 1.25E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS08930 992a18b9e7baf2adb2e3efcea9e465a6 274 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 173 201 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS01800 44ab658c84c52fa394b8088b0a8c68f9 554 PANTHER PTHR30607 4 553 2.5E-268 T 23-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 DC74_RS01800 44ab658c84c52fa394b8088b0a8c68f9 554 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 554 32.289 T 23-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 DC74_RS01800 44ab658c84c52fa394b8088b0a8c68f9 554 Pfam PF03814 Potassium-transporting ATPase A subunit 14 553 1.4E-225 T 23-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 DC74_RS01800 44ab658c84c52fa394b8088b0a8c68f9 554 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 5 553 4.9E-213 T 23-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 DC74_RS01800 44ab658c84c52fa394b8088b0a8c68f9 554 PIRSF PIRSF001294 3 554 1.7E-216 T 23-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 DC74_RS18210 dbc772c00169a6c9d6d3c6dbf2ef10a1 372 Pfam PF01381 Helix-turn-helix 2 55 7.9E-11 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS18210 dbc772c00169a6c9d6d3c6dbf2ef10a1 372 SMART SM00530 1 55 2.2E-10 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS18210 dbc772c00169a6c9d6d3c6dbf2ef10a1 372 Gene3D G3DSA:1.10.260.40 2 91 2.2E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS18210 dbc772c00169a6c9d6d3c6dbf2ef10a1 372 SUPERFAMILY SSF47413 3 61 2.7E-12 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS38075 963db68dcbb1dae0d62ec137f4b7a7f4 198 Pfam PF01338 Bacillus thuringiensis toxin 7 194 9.5E-23 T 23-04-2016 IPR001615 Delta-endotoxin CytB GO:0005576|GO:0009405 DC74_RS38075 963db68dcbb1dae0d62ec137f4b7a7f4 198 ProDom PD009844 CYTOLYTIC TOXIN DELTA-ENDOTOXIN SPORULATION PLASMID TYPE-1AA TOCIN 3D-STRUCTURE CRYET29 TYPE-1BA 5 197 4.0E-22 T 23-04-2016 IPR001615 Delta-endotoxin CytB GO:0005576|GO:0009405 DC74_RS38075 963db68dcbb1dae0d62ec137f4b7a7f4 198 Gene3D G3DSA:3.40.198.10 7 195 2.7E-38 T 23-04-2016 IPR001615 Delta-endotoxin CytB GO:0005576|GO:0009405 DC74_RS38075 963db68dcbb1dae0d62ec137f4b7a7f4 198 SUPERFAMILY SSF55676 6 195 3.92E-26 T 23-04-2016 IPR001615 Delta-endotoxin CytB GO:0005576|GO:0009405 DC74_RS32470 1c6c32dd449efed65c7521f45676dc00 299 PANTHER PTHR23200 1 276 8.8E-87 T 23-04-2016 DC74_RS32470 1c6c32dd449efed65c7521f45676dc00 299 SMART SM00849 58 274 1.4E-22 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS32470 1c6c32dd449efed65c7521f45676dc00 299 Gene3D G3DSA:3.60.15.10 4 288 3.9E-49 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS32470 1c6c32dd449efed65c7521f45676dc00 299 Pfam PF00753 Metallo-beta-lactamase superfamily 59 274 9.5E-22 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS32470 1c6c32dd449efed65c7521f45676dc00 299 SUPERFAMILY SSF56281 52 290 4.32E-41 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS32470 1c6c32dd449efed65c7521f45676dc00 299 PANTHER PTHR23200:SF43 1 276 8.8E-87 T 23-04-2016 DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 SUPERFAMILY SSF50249 130 186 1.8E-18 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 SUPERFAMILY SSF50104 2 64 3.19E-18 T 23-04-2016 IPR008991 Translation protein SH3-like domain DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 Gene3D G3DSA:2.40.50.140 130 186 1.9E-28 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 SUPERFAMILY SSF50249 66 130 6.43E-18 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 9.0E-19 T 23-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 23-04-2016 IPR013852 Translation elongation factor P/YeiP, conserved site UniPathway: UPA00345 DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 61 5.2E-25 T 23-04-2016 IPR013185 Translation elongation factor, KOW-like UniPathway: UPA00345 DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 SMART SM01185 68 122 1.2E-23 T 23-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 Gene3D G3DSA:2.40.50.140 66 128 5.6E-23 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 TIGRFAM TIGR00038 efp: translation elongation factor P 3 186 1.7E-73 T 23-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 PANTHER PTHR30053 3 187 1.8E-85 T 23-04-2016 DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 Gene3D G3DSA:2.30.30.30 3 64 7.5E-30 T 23-04-2016 IPR014722 Ribosomal protein L2 domain 2 DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 Hamap MF_00141 Elongation factor P [efp]. 1 186 49.27 T 23-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 PIRSF PIRSF005901 1 187 9.3E-66 T 23-04-2016 IPR020599 Translation elongation factor P/YeiP UniPathway: UPA00345 DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 SMART SM00841 130 185 1.1E-32 T 23-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 DC74_RS09475 70762749b3119e8e0fe097891cc99b87 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 3.3E-26 T 23-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 DC74_RS17900 2c467db6ce9088c9a9d3e20b4c8bbc99 269 Gene3D G3DSA:3.40.1410.10 96 249 2.2E-37 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS17900 2c467db6ce9088c9a9d3e20b4c8bbc99 269 Gene3D G3DSA:1.10.10.10 19 87 1.9E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17900 2c467db6ce9088c9a9d3e20b4c8bbc99 269 SUPERFAMILY SSF64288 75 251 1.73E-36 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS17900 2c467db6ce9088c9a9d3e20b4c8bbc99 269 SMART SM00345 30 87 5.8E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS17900 2c467db6ce9088c9a9d3e20b4c8bbc99 269 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 6.6E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS17900 2c467db6ce9088c9a9d3e20b4c8bbc99 269 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 6.6E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS17900 2c467db6ce9088c9a9d3e20b4c8bbc99 269 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 85 2.1E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS17900 2c467db6ce9088c9a9d3e20b4c8bbc99 269 Pfam PF07702 UTRA domain 109 245 3.3E-31 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS17900 2c467db6ce9088c9a9d3e20b4c8bbc99 269 SUPERFAMILY SSF46785 19 91 1.08E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17900 2c467db6ce9088c9a9d3e20b4c8bbc99 269 SMART SM00866 108 246 6.2E-29 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS25470 950cadffae0407d34246430566c85c24 245 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 106 123 7.1E-6 T 23-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS25470 950cadffae0407d34246430566c85c24 245 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 163 173 7.1E-6 T 23-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS25470 950cadffae0407d34246430566c85c24 245 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 174 185 7.1E-6 T 23-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS25470 950cadffae0407d34246430566c85c24 245 PANTHER PTHR30487 3 240 6.1E-24 T 23-04-2016 DC74_RS25470 950cadffae0407d34246430566c85c24 245 PANTHER PTHR30487:SF0 3 240 6.1E-24 T 23-04-2016 DC74_RS25470 950cadffae0407d34246430566c85c24 245 Pfam PF01478 Type IV leader peptidase family 100 197 3.8E-11 T 23-04-2016 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 DC74_RS18650 38269069d33ab50fc10143e6cb6193bb 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.546 T 23-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 DC74_RS18650 38269069d33ab50fc10143e6cb6193bb 60 Gene3D G3DSA:3.30.1390.20 1 59 3.0E-27 T 23-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain DC74_RS18650 38269069d33ab50fc10143e6cb6193bb 60 PANTHER PTHR15892:SF2 1 60 1.2E-22 T 23-04-2016 DC74_RS18650 38269069d33ab50fc10143e6cb6193bb 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 2.0E-25 T 23-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 DC74_RS18650 38269069d33ab50fc10143e6cb6193bb 60 PIRSF PIRSF002211 1 60 4.7E-28 T 23-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 DC74_RS18650 38269069d33ab50fc10143e6cb6193bb 60 PANTHER PTHR15892 1 60 1.2E-22 T 23-04-2016 DC74_RS18650 38269069d33ab50fc10143e6cb6193bb 60 SUPERFAMILY SSF55129 1 60 3.66E-21 T 23-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain DC74_RS18650 38269069d33ab50fc10143e6cb6193bb 60 Pfam PF00327 Ribosomal protein L30p/L7e 5 54 9.3E-18 T 23-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain DC74_RS07660 465427b5cff50cbbbf17b4639c74a2c1 132 SUPERFAMILY SSF46785 14 125 1.05E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07660 465427b5cff50cbbbf17b4639c74a2c1 132 Pfam PF01638 HxlR-like helix-turn-helix 26 113 9.4E-28 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS07660 465427b5cff50cbbbf17b4639c74a2c1 132 Gene3D G3DSA:1.10.10.10 9 125 1.3E-43 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07660 465427b5cff50cbbbf17b4639c74a2c1 132 PANTHER PTHR33204 4 127 6.1E-61 T 23-04-2016 DC74_RS07660 465427b5cff50cbbbf17b4639c74a2c1 132 PANTHER PTHR33204:SF6 4 127 6.1E-61 T 23-04-2016 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 120 131 - T 23-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 Gene3D G3DSA:3.30.1490.20 186 240 6.5E-21 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 PANTHER PTHR23132 2 373 1.6E-175 T 23-04-2016 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 11 370 1.9E-104 T 23-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 Gene3D G3DSA:3.30.470.20 243 374 8.5E-47 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 10 371 41.253 T 23-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 PANTHER PTHR23132:SF8 2 373 1.6E-175 T 23-04-2016 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 SUPERFAMILY SSF56059 153 373 2.83E-53 T 23-04-2016 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 PIRSF PIRSF039102 7 377 9.5E-110 T 23-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 Pfam PF01820 D-ala D-ala ligase N-terminus 11 143 2.2E-34 T 23-04-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 Pfam PF07478 D-ala D-ala ligase C-terminus 161 368 3.6E-66 T 23-04-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 Gene3D G3DSA:3.40.50.20 9 142 2.1E-37 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 313 341 - T 23-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS27945 0bfa31cae983721ce64b20d3707877a1 378 SUPERFAMILY SSF52440 9 151 2.59E-35 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS07825 267a80a10243752b8154071cc9d05474 793 PANTHER PTHR32282:SF10 17 793 0.0 T 23-04-2016 DC74_RS07825 267a80a10243752b8154071cc9d05474 793 Gene3D G3DSA:1.20.1580.10 552 674 1.7E-34 T 23-04-2016 DC74_RS07825 267a80a10243752b8154071cc9d05474 793 SUPERFAMILY SSF52540 302 455 3.86E-33 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07825 267a80a10243752b8154071cc9d05474 793 SUPERFAMILY SSF52540 21 69 3.86E-33 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07825 267a80a10243752b8154071cc9d05474 793 PANTHER PTHR32282 17 793 0.0 T 23-04-2016 DC74_RS07825 267a80a10243752b8154071cc9d05474 793 Pfam PF00005 ABC transporter 504 712 3.4E-11 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS07825 267a80a10243752b8154071cc9d05474 793 SUPERFAMILY SSF52540 497 765 4.28E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07825 267a80a10243752b8154071cc9d05474 793 Gene3D G3DSA:1.20.1580.10 110 184 2.1E-31 T 23-04-2016 DC74_RS07825 267a80a10243752b8154071cc9d05474 793 Gene3D G3DSA:1.20.1580.10 298 363 2.1E-31 T 23-04-2016 DC74_RS07825 267a80a10243752b8154071cc9d05474 793 Gene3D G3DSA:3.40.50.300 364 479 1.6E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07825 267a80a10243752b8154071cc9d05474 793 Gene3D G3DSA:3.40.50.300 675 788 2.5E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07825 267a80a10243752b8154071cc9d05474 793 Gene3D G3DSA:3.40.50.300 488 548 2.5E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07825 267a80a10243752b8154071cc9d05474 793 Gene3D G3DSA:3.40.50.300 9 77 1.6E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07825 267a80a10243752b8154071cc9d05474 793 Gene3D G3DSA:1.10.8.280 187 297 2.1E-7 T 23-04-2016 DC74_RS08390 d761c2c361650a78e89212ae55c40b72 315 SUPERFAMILY SSF50249 162 290 1.71E-30 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS08390 d761c2c361650a78e89212ae55c40b72 315 PANTHER PTHR34075:SF1 124 309 5.1E-36 T 23-04-2016 DC74_RS08390 d761c2c361650a78e89212ae55c40b72 315 PANTHER PTHR34075 124 309 5.1E-36 T 23-04-2016 DC74_RS08390 d761c2c361650a78e89212ae55c40b72 315 SUPERFAMILY SSF50249 2 136 2.06E-26 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS08390 d761c2c361650a78e89212ae55c40b72 315 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 188 219 5.9E-9 T 23-04-2016 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DC74_RS08390 d761c2c361650a78e89212ae55c40b72 315 Gene3D G3DSA:2.40.50.140 83 132 4.4E-4 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS08390 d761c2c361650a78e89212ae55c40b72 315 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 225 288 2.2E-12 T 23-04-2016 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal DC74_RS08390 d761c2c361650a78e89212ae55c40b72 315 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 64 127 2.9E-11 T 23-04-2016 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal DC74_RS34310 0d1ea61d402e9b4c093277473a6b4209 195 SUPERFAMILY SSF88659 126 191 3.05E-15 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS34310 0d1ea61d402e9b4c093277473a6b4209 195 Gene3D G3DSA:1.10.10.10 128 192 5.0E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34310 0d1ea61d402e9b4c093277473a6b4209 195 PANTHER PTHR30173:SF16 7 191 1.1E-71 T 23-04-2016 DC74_RS34310 0d1ea61d402e9b4c093277473a6b4209 195 SUPERFAMILY SSF88946 17 104 1.88E-21 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS34310 0d1ea61d402e9b4c093277473a6b4209 195 Pfam PF04542 Sigma-70 region 2 36 103 1.4E-16 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS34310 0d1ea61d402e9b4c093277473a6b4209 195 Gene3D G3DSA:1.10.1740.10 19 115 1.1E-22 T 23-04-2016 DC74_RS34310 0d1ea61d402e9b4c093277473a6b4209 195 PANTHER PTHR30173 7 191 1.1E-71 T 23-04-2016 DC74_RS34310 0d1ea61d402e9b4c093277473a6b4209 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 191 7.1E-23 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS34310 0d1ea61d402e9b4c093277473a6b4209 195 Pfam PF08281 Sigma-70, region 4 134 187 2.4E-13 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS18555 ee6308a23e8f1fefcfd501ae8051dfc4 615 PANTHER PTHR10937:SF0 1 615 0.0 T 23-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 DC74_RS18555 ee6308a23e8f1fefcfd501ae8051dfc4 615 PANTHER PTHR10937 1 615 0.0 T 23-04-2016 DC74_RS18555 ee6308a23e8f1fefcfd501ae8051dfc4 615 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 615 1.7E-248 T 23-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 DC74_RS18555 ee6308a23e8f1fefcfd501ae8051dfc4 615 Gene3D G3DSA:3.40.50.10490 446 615 2.5E-60 T 23-04-2016 DC74_RS18555 ee6308a23e8f1fefcfd501ae8051dfc4 615 SUPERFAMILY SSF53697 247 615 6.87E-108 T 23-04-2016 DC74_RS18555 ee6308a23e8f1fefcfd501ae8051dfc4 615 Pfam PF13522 Glutamine amidotransferase domain 66 195 1.2E-23 T 23-04-2016 DC74_RS18555 ee6308a23e8f1fefcfd501ae8051dfc4 615 Gene3D G3DSA:3.60.20.10 2 242 3.7E-76 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS18555 ee6308a23e8f1fefcfd501ae8051dfc4 615 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 615 41.463 T 23-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 DC74_RS18555 ee6308a23e8f1fefcfd501ae8051dfc4 615 Gene3D G3DSA:3.40.50.10490 246 445 6.7E-75 T 23-04-2016 DC74_RS18555 ee6308a23e8f1fefcfd501ae8051dfc4 615 SUPERFAMILY SSF56235 2 234 8.15E-67 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS18555 ee6308a23e8f1fefcfd501ae8051dfc4 615 Pfam PF01380 SIS domain 292 418 9.2E-34 T 23-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 DC74_RS18555 ee6308a23e8f1fefcfd501ae8051dfc4 615 Pfam PF01380 SIS domain 464 596 2.0E-24 T 23-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 DC74_RS03085 a7d39046bddb9ec568870d1650cd0dd5 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 57 6.7E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03085 a7d39046bddb9ec568870d1650cd0dd5 214 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS03085 a7d39046bddb9ec568870d1650cd0dd5 214 Pfam PF13977 Bacterial transcriptional repressor 97 202 4.6E-22 T 23-04-2016 DC74_RS03085 a7d39046bddb9ec568870d1650cd0dd5 214 SUPERFAMILY SSF48498 96 203 1.96E-20 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS03085 a7d39046bddb9ec568870d1650cd0dd5 214 SUPERFAMILY SSF46689 5 77 1.28E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03085 a7d39046bddb9ec568870d1650cd0dd5 214 PANTHER PTHR30055 8 203 5.6E-15 T 23-04-2016 DC74_RS03085 a7d39046bddb9ec568870d1650cd0dd5 214 Gene3D G3DSA:1.10.357.10 1 203 2.8E-47 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS28300 68ce137a8b9d3637d1f45d64aba1c3cc 340 PANTHER PTHR11409 1 332 2.4E-152 T 23-04-2016 DC74_RS28300 68ce137a8b9d3637d1f45d64aba1c3cc 340 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 11 330 7.3E-84 T 23-04-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 DC74_RS28300 68ce137a8b9d3637d1f45d64aba1c3cc 340 Gene3D G3DSA:3.20.20.140 7 334 3.3E-95 T 23-04-2016 DC74_RS28300 68ce137a8b9d3637d1f45d64aba1c3cc 340 PANTHER PTHR11409:SF36 1 332 2.4E-152 T 23-04-2016 DC74_RS28300 68ce137a8b9d3637d1f45d64aba1c3cc 340 SUPERFAMILY SSF51556 7 334 3.84E-78 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS28300 68ce137a8b9d3637d1f45d64aba1c3cc 340 Pfam PF00962 Adenosine/AMP deaminase 11 327 3.7E-89 T 23-04-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 DC74_RS39455 9675e68e588e2f5645865973734c6066 196 Pfam PF00881 Nitroreductase family 22 74 3.3E-13 T 23-04-2016 IPR029479 Nitroreductase DC74_RS39455 9675e68e588e2f5645865973734c6066 196 Pfam PF00881 Nitroreductase family 101 164 2.6E-11 T 23-04-2016 IPR029479 Nitroreductase DC74_RS39455 9675e68e588e2f5645865973734c6066 196 PANTHER PTHR23026 16 191 2.6E-37 T 23-04-2016 DC74_RS39455 9675e68e588e2f5645865973734c6066 196 Gene3D G3DSA:3.40.109.10 17 190 2.3E-43 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS39455 9675e68e588e2f5645865973734c6066 196 SUPERFAMILY SSF55469 16 189 4.45E-45 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 SUPERFAMILY SSF52540 296 444 3.32E-28 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 SUPERFAMILY SSF52540 19 67 3.32E-28 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 PANTHER PTHR32282 15 536 0.0 T 23-04-2016 DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 ProSitePatterns PS00211 ABC transporters family signature. 718 732 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 SUPERFAMILY SSF52540 572 801 1.13E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 SUPERFAMILY SSF52540 492 534 1.13E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 Gene3D G3DSA:3.40.50.300 709 827 2.2E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 Gene3D G3DSA:3.40.50.300 19 66 6.6E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 Gene3D G3DSA:3.40.50.300 354 470 6.6E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 Gene3D G3DSA:3.40.50.300 474 544 2.2E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 140 813 7.3E-221 T 23-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 SMART SM00382 38 431 7.9 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 SMART SM00382 505 796 8.1E-5 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 Gene3D G3DSA:1.10.8.280 164 283 4.2E-24 T 23-04-2016 DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 Pfam PF00005 ABC transporter 497 748 2.1E-8 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 Gene3D G3DSA:1.20.1580.10 284 353 1.8E-29 T 23-04-2016 DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 Gene3D G3DSA:1.20.1580.10 108 162 1.8E-29 T 23-04-2016 DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 ProSitePatterns PS00211 ABC transporters family signature. 363 377 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 PANTHER PTHR32282 562 826 0.0 T 23-04-2016 DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 PANTHER PTHR32282:SF4 562 826 0.0 T 23-04-2016 DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 PANTHER PTHR32282:SF4 15 536 0.0 T 23-04-2016 DC74_RS33620 86e67449d3d62d0a2a749be275532848 834 Gene3D G3DSA:1.20.1580.10 582 708 1.7E-45 T 23-04-2016 DC74_RS34395 570bec4eff227b2b970d900a80d4f46c 250 Gene3D G3DSA:3.40.50.1000 121 237 1.4E-44 T 23-04-2016 IPR023214 HAD-like domain DC74_RS34395 570bec4eff227b2b970d900a80d4f46c 250 Gene3D G3DSA:3.40.50.1000 14 29 1.4E-44 T 23-04-2016 IPR023214 HAD-like domain DC74_RS34395 570bec4eff227b2b970d900a80d4f46c 250 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 109 216 7.0E-19 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34395 570bec4eff227b2b970d900a80d4f46c 250 PANTHER PTHR18901 4 234 3.5E-51 T 23-04-2016 DC74_RS34395 570bec4eff227b2b970d900a80d4f46c 250 Pfam PF13419 Haloacid dehalogenase-like hydrolase 18 217 3.1E-26 T 23-04-2016 IPR023214 HAD-like domain DC74_RS34395 570bec4eff227b2b970d900a80d4f46c 250 SUPERFAMILY SSF56784 16 238 1.96E-48 T 23-04-2016 IPR023214 HAD-like domain DC74_RS34395 570bec4eff227b2b970d900a80d4f46c 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 15 26 2.7E-9 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34395 570bec4eff227b2b970d900a80d4f46c 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 179 199 2.7E-9 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34395 570bec4eff227b2b970d900a80d4f46c 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 206 219 2.7E-9 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34395 570bec4eff227b2b970d900a80d4f46c 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 177 2.7E-9 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34395 570bec4eff227b2b970d900a80d4f46c 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 130 143 2.7E-9 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 Pfam PF13380 CoA binding domain 6 126 1.1E-14 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 PANTHER PTHR33303 2 672 1.2E-125 T 23-04-2016 DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 Pfam PF13549 ATP-grasp domain 472 668 6.4E-51 T 23-04-2016 DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 Gene3D G3DSA:3.40.50.720 2 120 1.6E-23 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 SMART SM00881 2 97 9.7E-15 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 SUPERFAMILY SSF56059 471 668 1.77E-30 T 23-04-2016 DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 Gene3D G3DSA:3.30.470.20 471 557 1.2E-6 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 SUPERFAMILY SSF51735 2 127 1.31E-22 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 SUPERFAMILY SSF52210 285 446 5.63E-21 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 Gene3D G3DSA:3.40.50.261 121 277 9.1E-27 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 142 278 4.5E-40 T 23-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 PANTHER PTHR33303:SF3 2 672 1.2E-125 T 23-04-2016 DC74_RS03225 75ee4daf5627c89787e0d406de55a14e 673 SUPERFAMILY SSF52210 137 280 2.75E-32 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS18320 94b8e1dafe4878afe17d9b47a866b53a 211 PIRSF PIRSF000190 8 211 4.2E-55 T 23-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS18320 94b8e1dafe4878afe17d9b47a866b53a 211 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 32 112 7.6E-21 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS18320 94b8e1dafe4878afe17d9b47a866b53a 211 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 170 211 2.0E-8 T 23-04-2016 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS18320 94b8e1dafe4878afe17d9b47a866b53a 211 SUPERFAMILY SSF50475 14 211 1.52E-46 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS18320 94b8e1dafe4878afe17d9b47a866b53a 211 PANTHER PTHR10851 17 211 2.2E-59 T 23-04-2016 DC74_RS18320 94b8e1dafe4878afe17d9b47a866b53a 211 PANTHER PTHR10851:SF0 17 211 2.2E-59 T 23-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS18320 94b8e1dafe4878afe17d9b47a866b53a 211 Gene3D G3DSA:2.30.110.10 16 211 9.1E-59 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS20945 3c77a9038543535cb2787cf4b81c7f99 188 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 50 66 7.6E-16 T 23-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 DC74_RS20945 3c77a9038543535cb2787cf4b81c7f99 188 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 7 24 7.6E-16 T 23-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 DC74_RS20945 3c77a9038543535cb2787cf4b81c7f99 188 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 107 120 7.6E-16 T 23-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 DC74_RS20945 3c77a9038543535cb2787cf4b81c7f99 188 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 83 98 7.6E-16 T 23-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 DC74_RS20945 3c77a9038543535cb2787cf4b81c7f99 188 SMART SM00226 5 160 2.1E-54 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS20945 3c77a9038543535cb2787cf4b81c7f99 188 PANTHER PTHR11717 6 164 1.4E-50 T 23-04-2016 DC74_RS20945 3c77a9038543535cb2787cf4b81c7f99 188 Gene3D G3DSA:3.40.50.270 5 164 6.4E-53 T 23-04-2016 DC74_RS20945 3c77a9038543535cb2787cf4b81c7f99 188 PANTHER PTHR11717:SF7 6 164 1.4E-50 T 23-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 DC74_RS20945 3c77a9038543535cb2787cf4b81c7f99 188 SUPERFAMILY SSF52788 4 161 1.31E-47 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS20945 3c77a9038543535cb2787cf4b81c7f99 188 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 158 1.3E-46 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS14740 0318257d5e40224ae3e5b2b860692fce 630 PANTHER PTHR11785:SF125 532 546 2.5E-117 T 23-04-2016 DC74_RS14740 0318257d5e40224ae3e5b2b860692fce 630 PANTHER PTHR11785:SF125 40 493 2.5E-117 T 23-04-2016 DC74_RS14740 0318257d5e40224ae3e5b2b860692fce 630 Pfam PF13520 Amino acid permease 69 443 5.2E-27 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS14740 0318257d5e40224ae3e5b2b860692fce 630 PANTHER PTHR11785 532 546 2.5E-117 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS14740 0318257d5e40224ae3e5b2b860692fce 630 PANTHER PTHR11785 40 493 2.5E-117 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS18615 367195bad337d2f4ef51b9953765a899 126 PIRSF PIRSF002134 1 125 5.3E-41 T 23-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18615 367195bad337d2f4ef51b9953765a899 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.9E-30 T 23-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18615 367195bad337d2f4ef51b9953765a899 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 26.888 T 23-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18615 367195bad337d2f4ef51b9953765a899 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 23-04-2016 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 DC74_RS18615 367195bad337d2f4ef51b9953765a899 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.6E-50 T 23-04-2016 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18615 367195bad337d2f4ef51b9953765a899 126 PANTHER PTHR10871 1 122 7.2E-68 T 23-04-2016 DC74_RS18615 367195bad337d2f4ef51b9953765a899 126 SUPERFAMILY SSF46946 2 122 3.14E-43 T 23-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 DC74_RS18615 367195bad337d2f4ef51b9953765a899 126 Gene3D G3DSA:4.10.910.10 73 124 3.8E-25 T 23-04-2016 IPR027437 30s ribosomal protein S13, C-terminal DC74_RS18615 367195bad337d2f4ef51b9953765a899 126 Gene3D G3DSA:1.10.8.50 1 72 7.9E-29 T 23-04-2016 DC74_RS05085 b328b20750cf2812798ac7d5cc5f189a 130 Gene3D G3DSA:1.10.10.10 4 127 9.6E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05085 b328b20750cf2812798ac7d5cc5f189a 130 ProSitePatterns PS01117 MarR-type HTH domain signature. 53 88 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS05085 b328b20750cf2812798ac7d5cc5f189a 130 Pfam PF01047 MarR family 22 79 1.0E-10 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS05085 b328b20750cf2812798ac7d5cc5f189a 130 PANTHER PTHR33164 1 130 6.6E-23 T 23-04-2016 DC74_RS05085 b328b20750cf2812798ac7d5cc5f189a 130 SUPERFAMILY SSF46785 2 127 2.68E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05085 b328b20750cf2812798ac7d5cc5f189a 130 SMART SM00347 15 115 2.5E-21 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS34895 51f9d8cf5eee0e52909ebb8ac30cc9be 70 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.2E-29 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS34895 51f9d8cf5eee0e52909ebb8ac30cc9be 70 PIRSF PIRSF002599 1 70 6.8E-26 T 23-04-2016 IPR012156 Cold shock, CspA GO:0003676 DC74_RS34895 51f9d8cf5eee0e52909ebb8ac30cc9be 70 SUPERFAMILY SSF50249 1 66 2.86E-24 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS34895 51f9d8cf5eee0e52909ebb8ac30cc9be 70 PRINTS PR00050 Cold shock protein signature 40 58 7.1E-17 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS34895 51f9d8cf5eee0e52909ebb8ac30cc9be 70 PRINTS PR00050 Cold shock protein signature 4 19 7.1E-17 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS34895 51f9d8cf5eee0e52909ebb8ac30cc9be 70 PRINTS PR00050 Cold shock protein signature 25 34 7.1E-17 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS34895 51f9d8cf5eee0e52909ebb8ac30cc9be 70 Gene3D G3DSA:2.40.50.140 1 68 4.6E-30 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS34895 51f9d8cf5eee0e52909ebb8ac30cc9be 70 PANTHER PTHR11544 1 67 1.0E-36 T 23-04-2016 DC74_RS34895 51f9d8cf5eee0e52909ebb8ac30cc9be 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 23-04-2016 IPR019844 Cold-shock conserved site DC74_RS34895 51f9d8cf5eee0e52909ebb8ac30cc9be 70 SMART SM00357 3 67 4.3E-30 T 23-04-2016 IPR011129 Cold shock protein GO:0003676 DC74_RS04895 19a664958276948c66ff9f65716bcd80 322 PANTHER PTHR11019:SF50 73 316 3.4E-29 T 23-04-2016 DC74_RS04895 19a664958276948c66ff9f65716bcd80 322 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 292 308 1.8E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS04895 19a664958276948c66ff9f65716bcd80 322 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 277 292 1.8E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS04895 19a664958276948c66ff9f65716bcd80 322 Pfam PF14525 AraC-binding-like domain 16 187 5.2E-21 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS04895 19a664958276948c66ff9f65716bcd80 322 Gene3D G3DSA:1.10.10.60 208 259 2.3E-6 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04895 19a664958276948c66ff9f65716bcd80 322 Pfam PF12833 Helix-turn-helix domain 229 310 7.9E-23 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS04895 19a664958276948c66ff9f65716bcd80 322 SUPERFAMILY SSF46689 259 310 2.02E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04895 19a664958276948c66ff9f65716bcd80 322 PANTHER PTHR11019 73 316 3.4E-29 T 23-04-2016 DC74_RS04895 19a664958276948c66ff9f65716bcd80 322 Gene3D G3DSA:1.10.10.60 260 307 1.7E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04895 19a664958276948c66ff9f65716bcd80 322 Gene3D G3DSA:2.60.120.10 28 105 9.7E-4 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS04895 19a664958276948c66ff9f65716bcd80 322 SMART SM00342 223 308 4.4E-26 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS25175 b02395a8958a5ac7e1040117dd433e2c 423 Pfam PF10979 Protein of unknown function (DUF2786) 187 226 1.2E-16 T 23-04-2016 IPR024498 Domain of unknown function DUF2786 DC74_RS25175 b02395a8958a5ac7e1040117dd433e2c 423 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 189 414 3.0E-59 T 23-04-2016 DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 PANTHER PTHR24321 6 249 4.4E-56 T 23-04-2016 DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 PANTHER PTHR24321:SF6 6 249 4.4E-56 T 23-04-2016 DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 Gene3D G3DSA:3.40.50.720 4 248 2.3E-88 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.9E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 4.9E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.9E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.9E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.9E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.9E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 SUPERFAMILY SSF51735 9 248 1.46E-83 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.3E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.3E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.3E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36290 dff5c540661b127aaed10a63a8c113b3 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 248 2.7E-67 T 23-04-2016 DC74_RS04215 29e7e6fc173197463c55a3628a6bf03d 388 PANTHER PTHR24421 42 382 1.4E-69 T 23-04-2016 DC74_RS04215 29e7e6fc173197463c55a3628a6bf03d 388 SUPERFAMILY SSF55874 247 362 8.61E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS04215 29e7e6fc173197463c55a3628a6bf03d 388 Gene3D G3DSA:3.30.565.10 245 315 1.3E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS04215 29e7e6fc173197463c55a3628a6bf03d 388 Pfam PF07730 Histidine kinase 161 224 5.9E-14 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS04215 29e7e6fc173197463c55a3628a6bf03d 388 PANTHER PTHR24421:SF26 42 382 1.4E-69 T 23-04-2016 DC74_RS35200 c8fbc6b674749f44dac1a9cb9a63d9f6 283 SUPERFAMILY SSF52402 5 139 5.53E-25 T 23-04-2016 DC74_RS35200 c8fbc6b674749f44dac1a9cb9a63d9f6 283 Gene3D G3DSA:3.40.50.620 4 137 5.7E-29 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS35200 c8fbc6b674749f44dac1a9cb9a63d9f6 283 PANTHER PTHR31964:SF42 6 152 5.7E-25 T 23-04-2016 DC74_RS35200 c8fbc6b674749f44dac1a9cb9a63d9f6 283 Pfam PF00582 Universal stress protein family 5 137 3.5E-21 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS35200 c8fbc6b674749f44dac1a9cb9a63d9f6 283 PANTHER PTHR31964 6 152 5.7E-25 T 23-04-2016 DC74_RS35200 c8fbc6b674749f44dac1a9cb9a63d9f6 283 PRINTS PR01438 Universal stress protein signature 115 137 1.6E-10 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS35200 c8fbc6b674749f44dac1a9cb9a63d9f6 283 PRINTS PR01438 Universal stress protein signature 2 20 1.6E-10 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS35200 c8fbc6b674749f44dac1a9cb9a63d9f6 283 PRINTS PR01438 Universal stress protein signature 97 109 1.6E-10 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS40635 5c96bf4fc05a5aa932bd99835e9c58b5 173 Gene3D G3DSA:3.40.50.2020 15 159 3.4E-24 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS40635 5c96bf4fc05a5aa932bd99835e9c58b5 173 Pfam PF00156 Phosphoribosyl transferase domain 22 159 2.2E-20 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 DC74_RS40635 5c96bf4fc05a5aa932bd99835e9c58b5 173 SUPERFAMILY SSF53271 14 156 5.11E-23 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS15245 f1c2ba9d5f3ae091efe87d6811d12099 535 SUPERFAMILY SSF55154 5 227 3.92E-40 T 23-04-2016 IPR033469 CYTH-like domain DC74_RS15245 f1c2ba9d5f3ae091efe87d6811d12099 535 Gene3D G3DSA:2.40.320.10 5 223 3.6E-51 T 23-04-2016 IPR023577 CYTH domain DC74_RS15245 f1c2ba9d5f3ae091efe87d6811d12099 535 Pfam PF01928 CYTH domain 40 195 5.7E-14 T 23-04-2016 IPR023577 CYTH domain DC74_RS15245 f1c2ba9d5f3ae091efe87d6811d12099 535 PANTHER PTHR39339:SF1 8 534 8.4E-61 T 23-04-2016 DC74_RS15245 f1c2ba9d5f3ae091efe87d6811d12099 535 Pfam PF05235 CHAD domain 251 483 1.3E-50 T 23-04-2016 IPR007899 CHAD domain DC74_RS15245 f1c2ba9d5f3ae091efe87d6811d12099 535 SMART SM00880 251 517 2.7E-58 T 23-04-2016 IPR007899 CHAD domain DC74_RS15245 f1c2ba9d5f3ae091efe87d6811d12099 535 SMART SM01118 5 218 2.2E-19 T 23-04-2016 IPR023577 CYTH domain DC74_RS15245 f1c2ba9d5f3ae091efe87d6811d12099 535 PANTHER PTHR39339 8 534 8.4E-61 T 23-04-2016 DC74_RS31440 7441e6ce7ef0c451b319a46660c84d90 638 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 48 186 5.0E-21 T 23-04-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS31440 7441e6ce7ef0c451b319a46660c84d90 638 SUPERFAMILY SSF51445 190 507 4.53E-102 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS31440 7441e6ce7ef0c451b319a46660c84d90 638 PANTHER PTHR13170 135 484 1.1E-87 T 23-04-2016 DC74_RS31440 7441e6ce7ef0c451b319a46660c84d90 638 Gene3D G3DSA:3.30.379.10 45 186 1.2E-17 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like DC74_RS31440 7441e6ce7ef0c451b319a46660c84d90 638 Pfam PF07555 beta-N-acetylglucosaminidase 192 500 1.2E-110 T 23-04-2016 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 DC74_RS31440 7441e6ce7ef0c451b319a46660c84d90 638 PANTHER PTHR13170:SF20 135 484 1.1E-87 T 23-04-2016 DC74_RS31440 7441e6ce7ef0c451b319a46660c84d90 638 SUPERFAMILY SSF55545 47 187 3.44E-17 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 SMART SM00825 Beta-ketoacyl synthase 431 835 2.4E-106 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 Gene3D G3DSA:3.40.47.10 674 835 4.3E-40 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 SUPERFAMILY SSF51735 30 237 3.66E-21 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 574 590 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 SMART SM00823 Phosphopantetheine attachment site 277 349 9.2E-5 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 SMART SM00823 Phosphopantetheine attachment site 1163 1234 8.7E-10 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 SUPERFAMILY SSF47336 413 442 2.75E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 SUPERFAMILY SSF47336 271 350 2.75E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 Pfam PF00550 Phosphopantetheine attachment site 279 345 1.4E-9 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 Pfam PF00550 Phosphopantetheine attachment site 1166 1230 1.7E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 669 782 2.0E-31 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 174 8.4E-11 T 23-04-2016 DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 Gene3D G3DSA:3.40.50.720 30 177 6.4E-22 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 430 661 6.2E-62 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 Gene3D G3DSA:3.40.47.10 431 673 4.9E-67 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 Pfam PF14765 Polyketide synthase dehydratase 872 1126 2.7E-28 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 Pfam PF08659 KR domain 2 173 8.2E-28 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 PANTHER PTHR11712:SF285 421 837 7.7E-119 T 23-04-2016 DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 PANTHER PTHR11712:SF285 248 379 7.7E-119 T 23-04-2016 DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 SMART SM00826 854 1014 5.3E-4 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 SUPERFAMILY SSF53901 429 780 2.95E-69 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 Gene3D G3DSA:1.10.1200.10 1164 1234 4.5E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 Gene3D G3DSA:1.10.1200.10 278 350 7.4E-8 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 SUPERFAMILY SSF47336 1164 1252 1.57E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 PANTHER PTHR11712 421 837 7.7E-119 T 23-04-2016 DC74_RS40510 388750f2ad5c9a7df86fd07c0c76920f 1421 PANTHER PTHR11712 248 379 7.7E-119 T 23-04-2016 DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 Pfam PF00501 AMP-binding enzyme 18 415 6.4E-82 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 ProSitePatterns PS00455 Putative AMP-binding domain signature. 158 169 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 PANTHER PTHR24095 13 1000 1.7E-191 T 23-04-2016 DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 Pfam PF00550 Phosphopantetheine attachment site 533 596 3.2E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 SUPERFAMILY SSF52777 796 1029 1.45E-35 T 23-04-2016 DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 498 1.3E-8 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 Pfam PF13745 HxxPF-repeated domain 924 995 1.8E-13 T 23-04-2016 DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 Gene3D G3DSA:3.40.50.980 186 326 1.2E-26 T 23-04-2016 DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 Gene3D G3DSA:1.10.1200.10 525 602 4.5E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 SUPERFAMILY SSF56801 13 510 1.31E-125 T 23-04-2016 DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 ProSitePatterns PS00012 Phosphopantetheine attachment site. 555 570 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 PANTHER PTHR24095:SF137 13 1000 1.7E-191 T 23-04-2016 DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 SUPERFAMILY SSF52777 617 789 2.45E-25 T 23-04-2016 DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 Gene3D G3DSA:3.40.50.980 13 181 5.3E-37 T 23-04-2016 DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 39 439 3.0E-110 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 Gene3D G3DSA:3.30.300.30 409 510 2.5E-25 T 23-04-2016 DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 Gene3D G3DSA:2.30.38.10 327 408 2.2E-23 T 23-04-2016 DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 SUPERFAMILY SSF47336 528 609 1.01E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 Pfam PF00668 Condensation domain 614 902 3.2E-32 T 23-04-2016 IPR001242 Condensation domain DC74_RS01880 a1200826250016b5be1019ce2a65a227 1032 SMART SM00823 Phosphopantetheine attachment site 530 600 1.1E-9 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 1.0E-9 T 23-04-2016 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.0E-9 T 23-04-2016 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 1.0E-9 T 23-04-2016 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 1.0E-9 T 23-04-2016 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 321 1.0E-39 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 Pfam PF14759 Reductase C-terminal 344 415 2.4E-8 T 23-04-2016 IPR028202 Reductase, C-terminal DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 Gene3D G3DSA:3.50.50.60 14 136 1.5E-27 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 SUPERFAMILY SSF51905 14 329 1.44E-34 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 Gene3D G3DSA:3.30.390.30 344 415 8.8E-18 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 SUPERFAMILY SSF55424 336 415 1.79E-17 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 PANTHER PTHR22912 6 389 4.3E-78 T 23-04-2016 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 Gene3D G3DSA:3.50.50.60 155 332 1.1E-30 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 2.5E-11 T 23-04-2016 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 2.5E-11 T 23-04-2016 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 2.5E-11 T 23-04-2016 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 244 258 2.5E-11 T 23-04-2016 DC74_RS06405 ff5b7ccc04a94e6a6f3956611dd13dab 464 PANTHER PTHR22912:SF180 6 389 4.3E-78 T 23-04-2016 DC74_RS13260 534f1915b67f027030097eb2cb279abb 350 Gene3D G3DSA:1.10.260.40 3 47 8.3E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS13260 534f1915b67f027030097eb2cb279abb 350 SMART SM00354 2 69 1.1E-22 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS13260 534f1915b67f027030097eb2cb279abb 350 Gene3D G3DSA:3.40.50.2300 58 170 4.5E-26 T 23-04-2016 DC74_RS13260 534f1915b67f027030097eb2cb279abb 350 SUPERFAMILY SSF47413 3 49 5.07E-12 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS13260 534f1915b67f027030097eb2cb279abb 350 Gene3D G3DSA:3.40.50.2300 171 334 8.1E-54 T 23-04-2016 DC74_RS13260 534f1915b67f027030097eb2cb279abb 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 3.9E-14 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS13260 534f1915b67f027030097eb2cb279abb 350 PANTHER PTHR30146 1 339 1.6E-109 T 23-04-2016 DC74_RS13260 534f1915b67f027030097eb2cb279abb 350 SUPERFAMILY SSF53822 59 337 5.89E-67 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS13260 534f1915b67f027030097eb2cb279abb 350 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS13260 534f1915b67f027030097eb2cb279abb 350 PANTHER PTHR30146:SF4 1 339 1.6E-109 T 23-04-2016 DC74_RS13260 534f1915b67f027030097eb2cb279abb 350 Pfam PF13377 Periplasmic binding protein-like domain 171 333 4.0E-37 T 23-04-2016 DC74_RS32530 bf621ee379d15c1be72d6e59f5029360 514 Gene3D G3DSA:3.50.50.60 5 225 7.5E-52 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS32530 bf621ee379d15c1be72d6e59f5029360 514 Gene3D G3DSA:3.50.50.60 332 473 5.2E-7 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS32530 bf621ee379d15c1be72d6e59f5029360 514 Pfam PF00743 Flavin-binding monooxygenase-like 90 229 5.1E-12 T 23-04-2016 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 DC74_RS32530 bf621ee379d15c1be72d6e59f5029360 514 SUPERFAMILY SSF51905 11 398 8.37E-51 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS32530 bf621ee379d15c1be72d6e59f5029360 514 PANTHER PTHR23023 11 476 3.7E-192 T 23-04-2016 DC74_RS32530 bf621ee379d15c1be72d6e59f5029360 514 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 3.8E-5 T 23-04-2016 DC74_RS32530 bf621ee379d15c1be72d6e59f5029360 514 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 188 213 3.8E-5 T 23-04-2016 DC74_RS32530 bf621ee379d15c1be72d6e59f5029360 514 PANTHER PTHR23023:SF30 11 476 3.7E-192 T 23-04-2016 DC74_RS32530 bf621ee379d15c1be72d6e59f5029360 514 Pfam PF13450 NAD(P)-binding Rossmann-like domain 18 75 2.5E-7 T 23-04-2016 DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 PRINTS PR00338 Transcription termination factor NUSG signature 159 171 4.4E-18 T 23-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 PRINTS PR00338 Transcription termination factor NUSG signature 252 267 4.4E-18 T 23-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 PRINTS PR00338 Transcription termination factor NUSG signature 270 286 4.4E-18 T 23-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 SMART SM00738 104 212 1.6E-45 T 23-04-2016 IPR006645 NusG, N-terminal GO:0006355 DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 104 294 22.649 T 23-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 PANTHER PTHR30265 20 293 3.4E-63 T 23-04-2016 DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 SMART SM00739 240 267 3.5E-4 T 23-04-2016 IPR005824 KOW DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 107 293 1.9E-54 T 23-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 SUPERFAMILY SSF82679 106 212 3.66E-35 T 23-04-2016 IPR006645 NusG, N-terminal GO:0006355 DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 ProSitePatterns PS01014 Transcription termination factor nusG signature. 277 286 - T 23-04-2016 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 SUPERFAMILY SSF50104 239 293 5.01E-15 T 23-04-2016 IPR008991 Translation protein SH3-like domain DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 Pfam PF02357 Transcription termination factor nusG 106 208 1.6E-22 T 23-04-2016 IPR006645 NusG, N-terminal GO:0006355 DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 Gene3D G3DSA:2.30.30.30 239 293 2.0E-25 T 23-04-2016 IPR014722 Ribosomal protein L2 domain 2 DC74_RS18805 a8a811b19fe3dd6c1730122c1126e905 294 Gene3D G3DSA:3.30.70.940 106 214 1.7E-41 T 23-04-2016 IPR006645 NusG, N-terminal GO:0006355 DC74_RS08630 607c542a7219e0be4a5184887683dc2d 303 SUPERFAMILY SSF161098 57 285 2.62E-51 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS08630 607c542a7219e0be4a5184887683dc2d 303 PANTHER PTHR30406:SF2 1 303 3.3E-101 T 23-04-2016 DC74_RS08630 607c542a7219e0be4a5184887683dc2d 303 Gene3D G3DSA:1.10.3720.10 8 288 1.2E-54 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS08630 607c542a7219e0be4a5184887683dc2d 303 PANTHER PTHR30406 1 303 3.3E-101 T 23-04-2016 DC74_RS08630 607c542a7219e0be4a5184887683dc2d 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 297 4.0E-17 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS19165 e9b0d78087dd0d8dc00da6f3d033f7df 97 Pfam PF06013 Proteins of 100 residues with WXG 7 91 2.9E-16 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS19165 e9b0d78087dd0d8dc00da6f3d033f7df 97 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 7 94 2.9E-20 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS19165 e9b0d78087dd0d8dc00da6f3d033f7df 97 Gene3D G3DSA:1.10.287.1060 6 97 2.3E-22 T 23-04-2016 DC74_RS19165 e9b0d78087dd0d8dc00da6f3d033f7df 97 SUPERFAMILY SSF140453 7 97 1.57E-20 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS18135 0d11f5faf415df09a8b98bcb45f7e0a0 516 PANTHER PTHR11819 2 496 3.2E-162 T 23-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS18135 0d11f5faf415df09a8b98bcb45f7e0a0 516 PANTHER PTHR11819:SF141 2 496 3.2E-162 T 23-04-2016 DC74_RS18135 0d11f5faf415df09a8b98bcb45f7e0a0 516 Pfam PF00474 Sodium:solute symporter family 33 417 5.0E-28 T 23-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS28325 432e3954b2e2068bbfb579d09a77b184 312 PANTHER PTHR30193 5 310 1.8E-122 T 23-04-2016 DC74_RS28325 432e3954b2e2068bbfb579d09a77b184 312 PANTHER PTHR30193:SF10 5 310 1.8E-122 T 23-04-2016 DC74_RS28325 432e3954b2e2068bbfb579d09a77b184 312 SUPERFAMILY SSF161098 27 305 2.49E-50 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28325 432e3954b2e2068bbfb579d09a77b184 312 Gene3D G3DSA:1.10.3720.10 23 302 2.3E-49 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28325 432e3954b2e2068bbfb579d09a77b184 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 299 2.6E-11 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 Gene3D G3DSA:3.30.70.920 245 293 5.7E-4 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 Gene3D G3DSA:3.30.70.920 69 141 8.2E-13 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 SMART SM00344 179 284 2.1E-5 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 PANTHER PTHR30154 1 167 7.7E-17 T 23-04-2016 DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 SUPERFAMILY SSF46785 179 220 2.73E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 SUPERFAMILY SSF54909 238 317 3.08E-6 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 Gene3D G3DSA:1.10.10.10 10 51 1.9E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 195 206 5.5E-6 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 179 195 5.5E-6 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 206 225 5.5E-6 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 Pfam PF13404 AsnC-type helix-turn-helix domain 179 219 1.1E-12 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 Pfam PF13404 AsnC-type helix-turn-helix domain 9 48 1.0E-7 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 Gene3D G3DSA:1.10.10.10 177 220 1.7E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 Pfam PF01037 Lrp/AsnC ligand binding domain 251 299 3.4E-6 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 Pfam PF01037 Lrp/AsnC ligand binding domain 72 138 5.1E-11 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS02690 7b612011c388ffb6838c58f64497a091 346 SUPERFAMILY SSF54909 68 149 1.34E-12 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS12110 80026a800bc554d56cfd82ccc36c0983 238 Gene3D G3DSA:3.40.50.300 2 233 1.5E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12110 80026a800bc554d56cfd82ccc36c0983 238 SMART SM00382 29 214 3.3E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS12110 80026a800bc554d56cfd82ccc36c0983 238 PANTHER PTHR24220 6 238 1.4E-128 T 23-04-2016 DC74_RS12110 80026a800bc554d56cfd82ccc36c0983 238 SUPERFAMILY SSF52540 3 235 2.66E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12110 80026a800bc554d56cfd82ccc36c0983 238 PIRSF PIRSF039137 1 238 8.5E-108 T 23-04-2016 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 DC74_RS12110 80026a800bc554d56cfd82ccc36c0983 238 PANTHER PTHR24220:SF568 6 238 1.4E-128 T 23-04-2016 DC74_RS12110 80026a800bc554d56cfd82ccc36c0983 238 Pfam PF00005 ABC transporter 21 165 4.8E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS12110 80026a800bc554d56cfd82ccc36c0983 238 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS16780 84135a04d85bb473cfe82aebea65a3ab 328 SUPERFAMILY SSF53448 1 176 2.56E-36 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS16780 84135a04d85bb473cfe82aebea65a3ab 328 PANTHER PTHR10859:SF81 1 306 1.6E-157 T 23-04-2016 DC74_RS16780 84135a04d85bb473cfe82aebea65a3ab 328 Gene3D G3DSA:3.90.550.10 1 117 1.5E-23 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS16780 84135a04d85bb473cfe82aebea65a3ab 328 PANTHER PTHR10859 1 306 1.6E-157 T 23-04-2016 DC74_RS16780 84135a04d85bb473cfe82aebea65a3ab 328 Pfam PF00535 Glycosyl transferase family 2 4 166 1.4E-27 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS38365 14738a80e161947517e2fd7db9c1f24c 356 PIRSF PIRSF001439 17 348 4.7E-77 T 23-04-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin DC74_RS38365 14738a80e161947517e2fd7db9c1f24c 356 SUPERFAMILY SSF51735 22 347 1.14E-63 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38365 14738a80e161947517e2fd7db9c1f24c 356 Gene3D G3DSA:3.30.1780.10 22 162 1.3E-38 T 23-04-2016 IPR023401 Ornithine cyclodeaminase, N-terminal DC74_RS38365 14738a80e161947517e2fd7db9c1f24c 356 PANTHER PTHR13812 15 350 1.2E-30 T 23-04-2016 DC74_RS38365 14738a80e161947517e2fd7db9c1f24c 356 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 23 348 7.0E-125 T 23-04-2016 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB DC74_RS38365 14738a80e161947517e2fd7db9c1f24c 356 Gene3D G3DSA:3.40.50.720 163 317 3.6E-14 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38365 14738a80e161947517e2fd7db9c1f24c 356 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 40 337 3.5E-29 T 23-04-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 PANTHER PTHR11748:SF35 243 569 7.5E-128 T 23-04-2016 DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 PANTHER PTHR11748:SF35 6 184 7.5E-128 T 23-04-2016 DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 SUPERFAMILY SSF46548 496 638 7.32E-9 T 23-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 Gene3D G3DSA:3.30.465.10 96 270 9.4E-36 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 SUPERFAMILY SSF56176 7 270 1.59E-54 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 PANTHER PTHR11748 243 569 7.5E-128 T 23-04-2016 DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 PANTHER PTHR11748 6 184 7.5E-128 T 23-04-2016 DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 Gene3D G3DSA:3.30.43.10 11 95 7.7E-19 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 Pfam PF13183 4Fe-4S dicluster domain 557 634 5.2E-9 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 Pfam PF01565 FAD binding domain 41 177 1.0E-39 T 23-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 Pfam PF02913 FAD linked oxidases, C-terminal domain 270 520 9.0E-54 T 23-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 Gene3D G3DSA:1.10.1060.10 497 643 2.3E-13 T 23-04-2016 DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 Pfam PF02754 Cysteine-rich domain 860 936 0.012 T 23-04-2016 IPR004017 Cysteine-rich domain DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 SUPERFAMILY SSF55103 245 522 3.6E-54 T 23-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DC74_RS01085 24b7d82e7e67a25c849402d895be31d0 983 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 620 631 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 SUPERFAMILY SSF51306 93 141 4.71E-45 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 SUPERFAMILY SSF51306 168 275 4.71E-45 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 PANTHER PTHR12383:SF14 68 140 5.4E-66 T 23-04-2016 DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 PANTHER PTHR12383:SF14 171 275 5.4E-66 T 23-04-2016 DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 80 270 1.4E-38 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 Pfam PF00717 Peptidase S24-like 101 197 9.7E-15 T 23-04-2016 IPR019759 Peptidase S24/S26A/S26B DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 ProSitePatterns PS00761 Signal peptidases I signature 3. 228 241 - T 23-04-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 Gene3D G3DSA:2.10.109.10 223 275 1.7E-39 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 Gene3D G3DSA:2.10.109.10 90 183 1.7E-39 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 173 185 1.2E-19 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 223 242 1.2E-19 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 94 110 1.2E-19 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 PANTHER PTHR12383 68 140 5.4E-66 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28145 3fd914e6a5c047cd68c3d2dea034ffce 320 PANTHER PTHR12383 171 275 5.4E-66 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS06635 6cd35a471432818b2f5639f0de2cbb1e 198 Pfam PF00583 Acetyltransferase (GNAT) family 97 164 2.7E-13 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS06635 6cd35a471432818b2f5639f0de2cbb1e 198 SUPERFAMILY SSF55729 27 186 1.11E-24 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06635 6cd35a471432818b2f5639f0de2cbb1e 198 PANTHER PTHR23091 55 190 1.3E-13 T 23-04-2016 DC74_RS06635 6cd35a471432818b2f5639f0de2cbb1e 198 Gene3D G3DSA:3.40.630.30 36 184 2.7E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31360 dea46d4d3d113c6c27c510f2a5e94f5e 467 PANTHER PTHR11271:SF37 13 462 2.8E-227 T 23-04-2016 DC74_RS31360 dea46d4d3d113c6c27c510f2a5e94f5e 467 PANTHER PTHR11271 13 462 2.8E-227 T 23-04-2016 DC74_RS31360 dea46d4d3d113c6c27c510f2a5e94f5e 467 SUPERFAMILY SSF51556 72 387 1.53E-88 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS31360 dea46d4d3d113c6c27c510f2a5e94f5e 467 Pfam PF01979 Amidohydrolase family 69 433 2.6E-57 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS31360 dea46d4d3d113c6c27c510f2a5e94f5e 467 Gene3D G3DSA:2.30.40.10 12 74 2.2E-15 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS31360 dea46d4d3d113c6c27c510f2a5e94f5e 467 Gene3D G3DSA:2.30.40.10 396 435 2.2E-15 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS31360 dea46d4d3d113c6c27c510f2a5e94f5e 467 SUPERFAMILY SSF51338 343 464 2.4E-27 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS31360 dea46d4d3d113c6c27c510f2a5e94f5e 467 Gene3D G3DSA:3.20.20.140 75 395 1.5E-100 T 23-04-2016 DC74_RS31360 dea46d4d3d113c6c27c510f2a5e94f5e 467 SUPERFAMILY SSF51338 14 86 1.81E-10 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS11085 3f839253566ab5b07f5675b8609d1008 541 Pfam PF07905 Purine catabolism regulatory protein-like family 16 136 1.2E-36 T 23-04-2016 IPR012914 Purine catabolism PurC-like domain DC74_RS11085 3f839253566ab5b07f5675b8609d1008 541 Pfam PF13556 PucR C-terminal helix-turn-helix domain 477 535 8.0E-18 T 23-04-2016 IPR025736 PucR C-terminal helix-turn-helix domain DC74_RS11085 3f839253566ab5b07f5675b8609d1008 541 Gene3D G3DSA:1.10.10.60 482 512 4.4E-6 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS11085 3f839253566ab5b07f5675b8609d1008 541 PANTHER PTHR33744:SF5 13 538 1.5E-162 T 23-04-2016 DC74_RS11085 3f839253566ab5b07f5675b8609d1008 541 PANTHER PTHR33744 13 538 1.5E-162 T 23-04-2016 DC74_RS23580 4b26f6e82b877ce30dfddf3199e1fd0c 270 SUPERFAMILY SSF46689 2 58 1.38E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS23580 4b26f6e82b877ce30dfddf3199e1fd0c 270 Gene3D G3DSA:1.10.10.10 2 59 8.9E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23580 4b26f6e82b877ce30dfddf3199e1fd0c 270 PANTHER PTHR30514:SF1 2 249 1.5E-63 T 23-04-2016 DC74_RS23580 4b26f6e82b877ce30dfddf3199e1fd0c 270 SUPERFAMILY SSF53697 80 262 2.37E-39 T 23-04-2016 DC74_RS23580 4b26f6e82b877ce30dfddf3199e1fd0c 270 Gene3D G3DSA:3.40.50.10490 82 250 4.4E-40 T 23-04-2016 DC74_RS23580 4b26f6e82b877ce30dfddf3199e1fd0c 270 PANTHER PTHR30514 2 249 1.5E-63 T 23-04-2016 DC74_RS23580 4b26f6e82b877ce30dfddf3199e1fd0c 270 Pfam PF01418 Helix-turn-helix domain, rpiR family 2 59 9.0E-12 T 23-04-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 DC74_RS23580 4b26f6e82b877ce30dfddf3199e1fd0c 270 Pfam PF01380 SIS domain 112 241 1.1E-22 T 23-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 DC74_RS18845 631d9add34f5e934b4d255f9d1543173 54 PANTHER PTHR15238 3 53 3.3E-21 T 23-04-2016 DC74_RS18845 631d9add34f5e934b4d255f9d1543173 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 4.5E-22 T 23-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18845 631d9add34f5e934b4d255f9d1543173 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 23-04-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18845 631d9add34f5e934b4d255f9d1543173 54 PANTHER PTHR15238:SF3 3 53 3.3E-21 T 23-04-2016 DC74_RS18845 631d9add34f5e934b4d255f9d1543173 54 SUPERFAMILY SSF57829 4 54 7.94E-20 T 23-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 DC74_RS18845 631d9add34f5e934b4d255f9d1543173 54 Pfam PF00471 Ribosomal protein L33 9 54 3.4E-23 T 23-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18845 631d9add34f5e934b4d255f9d1543173 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 19.492 T 23-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS27920 67bf63bb235419dad8723fa29cb7eb4f 219 Pfam PF00216 Bacterial DNA-binding protein 1 88 1.7E-22 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS27920 67bf63bb235419dad8723fa29cb7eb4f 219 SUPERFAMILY SSF47729 1 92 8.68E-24 T 23-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 DC74_RS27920 67bf63bb235419dad8723fa29cb7eb4f 219 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 23-04-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 DC74_RS27920 67bf63bb235419dad8723fa29cb7eb4f 219 PANTHER PTHR33175 1 97 3.6E-44 T 23-04-2016 DC74_RS27920 67bf63bb235419dad8723fa29cb7eb4f 219 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 4.6E-13 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS27920 67bf63bb235419dad8723fa29cb7eb4f 219 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 4.6E-13 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS27920 67bf63bb235419dad8723fa29cb7eb4f 219 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 4.6E-13 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS27920 67bf63bb235419dad8723fa29cb7eb4f 219 PANTHER PTHR33175:SF3 1 97 3.6E-44 T 23-04-2016 DC74_RS27920 67bf63bb235419dad8723fa29cb7eb4f 219 Gene3D G3DSA:4.10.520.10 1 89 8.8E-27 T 23-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 DC74_RS27920 67bf63bb235419dad8723fa29cb7eb4f 219 SMART SM00411 1 89 4.0E-37 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS11220 e63e0f786c058b3681a48968ae99336b 179 PANTHER PTHR30289 3 177 4.9E-85 T 23-04-2016 DC74_RS11220 e63e0f786c058b3681a48968ae99336b 179 Pfam PF01161 Phosphatidylethanolamine-binding protein 40 173 3.7E-38 T 23-04-2016 IPR008914 Phosphatidylethanolamine-binding protein DC74_RS11220 e63e0f786c058b3681a48968ae99336b 179 SUPERFAMILY SSF49777 8 167 1.96E-51 T 23-04-2016 IPR008914 Phosphatidylethanolamine-binding protein DC74_RS11220 e63e0f786c058b3681a48968ae99336b 179 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 42 170 3.7E-40 T 23-04-2016 IPR005247 YbhB/YbcL DC74_RS11220 e63e0f786c058b3681a48968ae99336b 179 Gene3D G3DSA:3.90.280.10 19 174 1.7E-54 T 23-04-2016 IPR008914 Phosphatidylethanolamine-binding protein DC74_RS11220 e63e0f786c058b3681a48968ae99336b 179 PANTHER PTHR30289:SF0 3 177 4.9E-85 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 176 186 - T 23-04-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 28 103 2.0E-19 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 SMART SM00929 113 153 3.7E-19 T 23-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 Gene3D G3DSA:3.40.50.740 303 376 8.4E-45 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 Gene3D G3DSA:3.40.50.740 510 713 8.4E-45 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 SUPERFAMILY SSF54862 106 241 1.55E-31 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 59 76 - T 23-04-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 32 683 5.6E-187 T 23-04-2016 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 Gene3D G3DSA:3.30.70.20 168 233 9.7E-4 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 Gene3D G3DSA:2.20.25.90 250 299 6.8E-11 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 Pfam PF00384 Molybdopterin oxidoreductase 303 437 4.6E-9 T 23-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 Pfam PF00384 Molybdopterin oxidoreductase 534 670 1.4E-9 T 23-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 250 298 6.2E-5 T 23-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 128 140 - T 23-04-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 SUPERFAMILY SSF50692 757 832 2.68E-9 T 23-04-2016 IPR009010 Aspartate decarboxylase-like domain DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 SUPERFAMILY SSF53706 237 708 2.36E-77 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 SUPERFAMILY SSF54292 30 102 8.56E-20 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 PANTHER PTHR11615:SF166 522 832 0.0 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 PANTHER PTHR11615:SF166 31 336 0.0 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 PANTHER PTHR11615:SF166 396 455 0.0 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 Pfam PF01568 Molydopterin dinucleotide binding domain 756 834 2.1E-9 T 23-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 PANTHER PTHR11615 522 832 0.0 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 PANTHER PTHR11615 31 336 0.0 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 PANTHER PTHR11615 396 455 0.0 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 113 147 2.8E-16 T 23-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 Gene3D G3DSA:3.10.20.30 30 84 4.0E-6 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 Gene3D G3DSA:2.40.40.20 757 824 1.4E-7 T 23-04-2016 DC74_RS19045 c65bfab6f5eaf1a024b10d25da47a8ec 855 SMART SM00926 246 300 6.6E-8 T 23-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 PANTHER PTHR18934:SF109 84 714 0.0 T 23-04-2016 DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 PANTHER PTHR18934:SF109 749 877 0.0 T 23-04-2016 DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 SMART SM00382 100 393 4.8E-5 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 Gene3D G3DSA:3.40.50.300 283 425 3.5E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 SUPERFAMILY SSF52540 82 610 1.91E-111 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 SMART SM00490 313 413 3.1E-15 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 22 1327 0.0 T 23-04-2016 IPR010222 RNA helicase HrpA GO:0004004 DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 605 708 2.5E-15 T 23-04-2016 IPR011709 Domain of unknown function DUF1605 DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 PANTHER PTHR18934 84 714 0.0 T 23-04-2016 DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 PANTHER PTHR18934 749 877 0.0 T 23-04-2016 DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 SMART SM00487 80 267 2.1E-27 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 Pfam PF00270 DEAD/DEAH box helicase 93 241 4.8E-7 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 SMART SM00847 473 568 7.4E-38 T 23-04-2016 IPR007502 Helicase-associated domain GO:0004386 DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 Gene3D G3DSA:3.40.50.300 84 241 1.2E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 Pfam PF04408 Helicase associated domain (HA2) 476 566 7.3E-18 T 23-04-2016 IPR007502 Helicase-associated domain GO:0004386 DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 Pfam PF00271 Helicase conserved C-terminal domain 295 412 8.0E-11 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS19650 38e6e2fd0b1e154c1bcacecd2f2d2163 1331 Pfam PF11898 Domain of unknown function (DUF3418) 722 1327 3.1E-231 T 23-04-2016 IPR024590 RNA helicase HrpA, C-terminal DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 PANTHER PTHR21060:SF11 4 408 4.3E-204 T 23-04-2016 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 Gene3D G3DSA:3.30.420.40 218 407 2.5E-77 T 23-04-2016 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 TIGRFAM TIGR00016 ackA: acetate kinase 5 408 4.3E-142 T 23-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 216 233 - T 23-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 Hamap MF_00020 Acetate kinase [ackA]. 1 411 176.102 T 23-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 PIRSF PIRSF000722 4 411 5.9E-142 T 23-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 Gene3D G3DSA:3.30.420.40 118 217 9.4E-11 T 23-04-2016 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 8 19 - T 23-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 PRINTS PR00471 Acetate kinase family signature 312 325 2.9E-44 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 PRINTS PR00471 Acetate kinase family signature 334 350 2.9E-44 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 PRINTS PR00471 Acetate kinase family signature 186 199 2.9E-44 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 PRINTS PR00471 Acetate kinase family signature 8 19 2.9E-44 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 PRINTS PR00471 Acetate kinase family signature 216 237 2.9E-44 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 PRINTS PR00471 Acetate kinase family signature 389 401 2.9E-44 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 Pfam PF00871 Acetokinase family 8 402 4.1E-147 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 SUPERFAMILY SSF53067 7 209 5.05E-60 T 23-04-2016 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 PANTHER PTHR21060 4 408 4.3E-204 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 DC74_RS27270 1c75d90d5537615ea4eb93aeeda08820 411 SUPERFAMILY SSF53067 171 408 2.47E-84 T 23-04-2016 DC74_RS40015 a7952d46a5a7f548a69ced64c33bff61 282 PANTHER PTHR11487 32 276 1.2E-31 T 23-04-2016 IPR012223 Thioesterase type II, NRPS/PKS/S-FAS GO:0009058 DC74_RS40015 a7952d46a5a7f548a69ced64c33bff61 282 PANTHER PTHR11487:SF0 32 276 1.2E-31 T 23-04-2016 DC74_RS40015 a7952d46a5a7f548a69ced64c33bff61 282 Pfam PF00975 Thioesterase domain 36 259 4.0E-28 T 23-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 DC74_RS40015 a7952d46a5a7f548a69ced64c33bff61 282 Gene3D G3DSA:3.40.50.1820 198 250 2.3E-27 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS40015 a7952d46a5a7f548a69ced64c33bff61 282 Gene3D G3DSA:3.40.50.1820 20 142 2.3E-27 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS40015 a7952d46a5a7f548a69ced64c33bff61 282 SUPERFAMILY SSF53474 20 258 2.15E-34 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS10345 8fba7b3a76fca41c127ca8b28ea51847 326 Gene3D G3DSA:3.10.330.20 2 75 7.1E-33 T 23-04-2016 DC74_RS10345 8fba7b3a76fca41c127ca8b28ea51847 326 PANTHER PTHR12133:SF1 2 279 3.6E-98 T 23-04-2016 DC74_RS10345 8fba7b3a76fca41c127ca8b28ea51847 326 Gene3D G3DSA:3.40.50.150 77 282 1.3E-65 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS10345 8fba7b3a76fca41c127ca8b28ea51847 326 SUPERFAMILY SSF53335 13 266 1.31E-72 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS10345 8fba7b3a76fca41c127ca8b28ea51847 326 PANTHER PTHR12133 2 279 3.6E-98 T 23-04-2016 DC74_RS10345 8fba7b3a76fca41c127ca8b28ea51847 326 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 11 61 1.7E-28 T 23-04-2016 DC74_RS10345 8fba7b3a76fca41c127ca8b28ea51847 326 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 80 244 3.3E-23 T 23-04-2016 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 DC74_RS12480 7c4b553da1db622ab5fc82e81dc308c8 313 Pfam PF00849 RNA pseudouridylate synthase 93 247 1.8E-31 T 23-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS12480 7c4b553da1db622ab5fc82e81dc308c8 313 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 139 153 - T 23-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS12480 7c4b553da1db622ab5fc82e81dc308c8 313 SUPERFAMILY SSF55120 82 309 5.55E-68 T 23-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS12480 7c4b553da1db622ab5fc82e81dc308c8 313 PANTHER PTHR11079:SF73 2 311 1.1E-102 T 23-04-2016 DC74_RS12480 7c4b553da1db622ab5fc82e81dc308c8 313 SUPERFAMILY SSF55174 19 69 6.06E-7 T 23-04-2016 DC74_RS12480 7c4b553da1db622ab5fc82e81dc308c8 313 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 308 5.9E-86 T 23-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS12480 7c4b553da1db622ab5fc82e81dc308c8 313 Pfam PF01479 S4 domain 19 62 5.8E-6 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS12480 7c4b553da1db622ab5fc82e81dc308c8 313 PANTHER PTHR11079 2 311 1.1E-102 T 23-04-2016 DC74_RS12480 7c4b553da1db622ab5fc82e81dc308c8 313 Gene3D G3DSA:3.10.290.10 19 59 2.5E-8 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS08230 88f4b140aa43f9d12852f58052b2d06d 137 Gene3D G3DSA:1.10.10.10 61 115 7.9E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08230 88f4b140aa43f9d12852f58052b2d06d 137 SUPERFAMILY SSF46785 72 114 2.33E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08230 88f4b140aa43f9d12852f58052b2d06d 137 Pfam PF05331 Protein of unknown function (DUF742) 21 137 3.6E-39 T 23-04-2016 IPR007995 Protein of unknown function DUF742 DC74_RS08230 88f4b140aa43f9d12852f58052b2d06d 137 PANTHER PTHR36221 1 137 2.1E-36 T 23-04-2016 DC74_RS15740 428ea129b406147c85f6da57d8f150fd 341 SMART SM00354 1 68 3.2E-23 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS15740 428ea129b406147c85f6da57d8f150fd 341 PANTHER PTHR30146 1 329 7.9E-91 T 23-04-2016 DC74_RS15740 428ea129b406147c85f6da57d8f150fd 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 6.3E-15 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS15740 428ea129b406147c85f6da57d8f150fd 341 Pfam PF13377 Periplasmic binding protein-like domain 165 326 1.2E-35 T 23-04-2016 DC74_RS15740 428ea129b406147c85f6da57d8f150fd 341 Gene3D G3DSA:3.40.50.2300 171 307 2.9E-40 T 23-04-2016 DC74_RS15740 428ea129b406147c85f6da57d8f150fd 341 Gene3D G3DSA:3.40.50.2300 51 170 3.9E-37 T 23-04-2016 DC74_RS15740 428ea129b406147c85f6da57d8f150fd 341 SUPERFAMILY SSF47413 2 56 1.88E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS15740 428ea129b406147c85f6da57d8f150fd 341 Gene3D G3DSA:1.10.260.40 1 50 3.5E-22 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS15740 428ea129b406147c85f6da57d8f150fd 341 SUPERFAMILY SSF53822 58 330 5.81E-62 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS12930 719f9fc93d7b4a9d28c5773b0f26b300 473 SUPERFAMILY SSF64307 401 471 3.92E-16 T 23-04-2016 IPR001455 TusA-like domain DC74_RS12930 719f9fc93d7b4a9d28c5773b0f26b300 473 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 404 428 - T 23-04-2016 IPR001455 TusA-like domain DC74_RS12930 719f9fc93d7b4a9d28c5773b0f26b300 473 Gene3D G3DSA:3.90.1150.10 243 367 1.1E-32 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS12930 719f9fc93d7b4a9d28c5773b0f26b300 473 Pfam PF01206 Sulfurtransferase TusA 403 470 2.3E-14 T 23-04-2016 IPR001455 TusA-like domain DC74_RS12930 719f9fc93d7b4a9d28c5773b0f26b300 473 PANTHER PTHR11601 3 404 5.0E-90 T 23-04-2016 DC74_RS12930 719f9fc93d7b4a9d28c5773b0f26b300 473 PANTHER PTHR11601:SF20 3 404 5.0E-90 T 23-04-2016 DC74_RS12930 719f9fc93d7b4a9d28c5773b0f26b300 473 Pfam PF00266 Aminotransferase class-V 3 361 7.0E-37 T 23-04-2016 IPR000192 Aminotransferase class V domain DC74_RS12930 719f9fc93d7b4a9d28c5773b0f26b300 473 SUPERFAMILY SSF53383 3 370 6.38E-73 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS12930 719f9fc93d7b4a9d28c5773b0f26b300 473 Gene3D G3DSA:3.40.640.10 14 242 1.3E-49 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS12930 719f9fc93d7b4a9d28c5773b0f26b300 473 Gene3D G3DSA:3.30.110.40 402 471 1.6E-19 T 23-04-2016 IPR001455 TusA-like domain DC74_RS37120 157635f8915675de124c755495f1bf50 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.4E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37120 157635f8915675de124c755495f1bf50 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.4E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37120 157635f8915675de124c755495f1bf50 208 PANTHER PTHR30055:SF47 2 195 1.8E-46 T 23-04-2016 DC74_RS37120 157635f8915675de124c755495f1bf50 208 SUPERFAMILY SSF46689 15 80 3.44E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS37120 157635f8915675de124c755495f1bf50 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 4.7E-16 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37120 157635f8915675de124c755495f1bf50 208 Gene3D G3DSA:1.10.357.10 17 194 5.8E-28 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS37120 157635f8915675de124c755495f1bf50 208 SUPERFAMILY SSF48498 87 188 2.84E-10 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS37120 157635f8915675de124c755495f1bf50 208 PANTHER PTHR30055 2 195 1.8E-46 T 23-04-2016 DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 PANTHER PTHR11014:SF106 12 259 1.3E-112 T 23-04-2016 DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 PANTHER PTHR11014:SF106 278 440 1.3E-112 T 23-04-2016 DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 Gene3D G3DSA:3.40.630.10 13 213 2.3E-58 T 23-04-2016 DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 Gene3D G3DSA:3.40.630.10 376 440 2.3E-58 T 23-04-2016 DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 SUPERFAMILY SSF55031 204 249 2.22E-10 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 SUPERFAMILY SSF55031 290 330 2.22E-10 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 83 92 - T 23-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 Pfam PF01546 Peptidase family M20/M25/M40 84 440 5.0E-37 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 SUPERFAMILY SSF53187 351 439 7.11E-53 T 23-04-2016 DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 SUPERFAMILY SSF53187 13 186 7.11E-53 T 23-04-2016 DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 Gene3D G3DSA:3.30.70.360 214 253 8.9E-23 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 Gene3D G3DSA:3.30.70.360 291 336 8.9E-23 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 PANTHER PTHR11014 12 259 1.3E-112 T 23-04-2016 DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 PANTHER PTHR11014 278 440 1.3E-112 T 23-04-2016 DC74_RS10520 b4a01313bfb81dc918f9f4e005333b83 441 Pfam PF07687 Peptidase dimerisation domain 201 329 1.4E-15 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS30600 366e59d842e0d72a3d97faeea6aa8102 342 SUPERFAMILY SSF49478 60 116 7.85E-8 T 23-04-2016 DC74_RS30600 366e59d842e0d72a3d97faeea6aa8102 342 Gene3D G3DSA:2.60.40.10 62 115 2.4E-4 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS30600 366e59d842e0d72a3d97faeea6aa8102 342 Pfam PF05738 Cna protein B-type domain 67 109 1.6E-6 T 23-04-2016 IPR008454 Collagen-binding surface protein Cna-like, B-type domain DC74_RS19465 04e409fb2322c25431ba277c69b87c75 262 TIGRFAM TIGR02952 Sig70_famx2: RNA polymerase sigma-70 factor, TIGR02952 family 88 257 2.4E-78 T 23-04-2016 IPR014298 RNA polymerase sigma-X type DC74_RS19465 04e409fb2322c25431ba277c69b87c75 262 Pfam PF04542 Sigma-70 region 2 103 170 1.1E-17 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS19465 04e409fb2322c25431ba277c69b87c75 262 Gene3D G3DSA:1.10.1740.10 87 195 7.2E-29 T 23-04-2016 DC74_RS19465 04e409fb2322c25431ba277c69b87c75 262 SUPERFAMILY SSF88659 187 257 1.7E-13 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS19465 04e409fb2322c25431ba277c69b87c75 262 SUPERFAMILY SSF88946 81 189 5.89E-27 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS19465 04e409fb2322c25431ba277c69b87c75 262 Pfam PF08281 Sigma-70, region 4 202 253 5.6E-14 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS19465 04e409fb2322c25431ba277c69b87c75 262 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 98 255 2.2E-29 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS19465 04e409fb2322c25431ba277c69b87c75 262 PANTHER PTHR30173 71 260 5.6E-58 T 23-04-2016 DC74_RS19465 04e409fb2322c25431ba277c69b87c75 262 PANTHER PTHR30173:SF13 71 260 5.6E-58 T 23-04-2016 DC74_RS19465 04e409fb2322c25431ba277c69b87c75 262 Gene3D G3DSA:1.10.10.10 196 258 7.1E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00035 a9d2e9ef30f2fa219bf3226f7402546d 327 Gene3D G3DSA:3.40.50.880 22 199 1.2E-39 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS00035 a9d2e9ef30f2fa219bf3226f7402546d 327 SUPERFAMILY SSF52317 22 200 8.46E-35 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS00035 a9d2e9ef30f2fa219bf3226f7402546d 327 SUPERFAMILY SSF46689 271 321 2.4E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00035 a9d2e9ef30f2fa219bf3226f7402546d 327 Pfam PF01965 DJ-1/PfpI family 94 179 1.6E-13 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS00035 a9d2e9ef30f2fa219bf3226f7402546d 327 Gene3D G3DSA:1.10.10.60 272 321 5.7E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00035 a9d2e9ef30f2fa219bf3226f7402546d 327 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 271 313 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS00035 a9d2e9ef30f2fa219bf3226f7402546d 327 Pfam PF12833 Helix-turn-helix domain 240 318 7.2E-21 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS00035 a9d2e9ef30f2fa219bf3226f7402546d 327 PANTHER PTHR11019 22 325 2.3E-107 T 23-04-2016 DC74_RS00035 a9d2e9ef30f2fa219bf3226f7402546d 327 SUPERFAMILY SSF46689 220 268 1.16E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00035 a9d2e9ef30f2fa219bf3226f7402546d 327 SMART SM00342 234 317 5.6E-29 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS00035 a9d2e9ef30f2fa219bf3226f7402546d 327 PANTHER PTHR11019:SF68 22 325 2.3E-107 T 23-04-2016 DC74_RS00035 a9d2e9ef30f2fa219bf3226f7402546d 327 Gene3D G3DSA:1.10.10.60 216 271 1.7E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS12435 dbccbbf181f68358286f6f0b1a72acf7 1185 PANTHER PTHR32294:SF0 5 1184 0.0 T 23-04-2016 DC74_RS12435 dbccbbf181f68358286f6f0b1a72acf7 1185 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 319 758 3.7E-164 T 23-04-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12435 dbccbbf181f68358286f6f0b1a72acf7 1185 PANTHER PTHR32294 5 1184 0.0 T 23-04-2016 DC74_RS12435 dbccbbf181f68358286f6f0b1a72acf7 1185 Gene3D G3DSA:2.40.50.140 1019 1103 2.8E-4 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS12435 dbccbbf181f68358286f6f0b1a72acf7 1185 Gene3D G3DSA:3.20.20.140 10 271 5.3E-40 T 23-04-2016 DC74_RS12435 dbccbbf181f68358286f6f0b1a72acf7 1185 SUPERFAMILY SSF89550 10 272 2.88E-30 T 23-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 DC74_RS12435 dbccbbf181f68358286f6f0b1a72acf7 1185 SMART SM00481 10 77 1.4E-29 T 23-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 DC74_RS12435 dbccbbf181f68358286f6f0b1a72acf7 1185 Pfam PF14579 Helix-hairpin-helix motif 832 920 7.3E-24 T 23-04-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12435 dbccbbf181f68358286f6f0b1a72acf7 1185 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 9 1063 0.0 T 23-04-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12435 dbccbbf181f68358286f6f0b1a72acf7 1185 Pfam PF02811 PHP domain 11 197 5.4E-44 T 23-04-2016 IPR004013 PHP domain GO:0003824 DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 SMART SM00421 175 232 8.6E-25 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 Pfam PF00196 Bacterial regulatory proteins, luxR family 177 231 8.3E-19 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 Pfam PF00072 Response regulator receiver domain 23 138 8.3E-24 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 SUPERFAMILY SSF46894 169 235 4.08E-20 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 PANTHER PTHR26402 21 231 2.0E-68 T 23-04-2016 DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 PANTHER PTHR26402:SF151 21 231 2.0E-68 T 23-04-2016 DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 208 8.2E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 208 220 8.2E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 192 8.2E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 Gene3D G3DSA:3.40.50.2300 20 178 3.5E-36 T 23-04-2016 DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 Gene3D G3DSA:1.10.10.10 179 234 3.0E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 SUPERFAMILY SSF52172 20 156 3.7E-28 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 SMART SM00448 21 138 2.2E-22 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS03880 b396ebbb5c6fab1bb81588503cb6b59f 241 ProSitePatterns PS00622 LuxR-type HTH domain signature. 192 219 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 SUPERFAMILY SSF48264 10 401 1.44E-91 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 PANTHER PTHR24286 38 401 2.5E-155 T 23-04-2016 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 Gene3D G3DSA:1.10.630.10 8 401 2.6E-111 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 Pfam PF00067 Cytochrome P450 31 369 1.1E-33 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 PANTHER PTHR24286:SF32 38 401 2.5E-155 T 23-04-2016 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 PRINTS PR00359 B-class P450 signature 123 139 6.2E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 PRINTS PR00359 B-class P450 signature 184 206 6.2E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 PRINTS PR00359 B-class P450 signature 282 309 6.2E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 PRINTS PR00359 B-class P450 signature 310 325 6.2E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 PRINTS PR00359 B-class P450 signature 341 350 6.2E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 PRINTS PR00359 B-class P450 signature 350 361 6.2E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 PRINTS PR00359 B-class P450 signature 140 155 6.2E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23755 2e6dc5bcf12bd3832fc99cdbe90a0c80 403 PRINTS PR00359 B-class P450 signature 265 276 6.2E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33035 9de3bb1fc5050ba4633f4051748e13f2 613 SUPERFAMILY SSF56801 13 301 8.24E-113 T 23-04-2016 DC74_RS33035 9de3bb1fc5050ba4633f4051748e13f2 613 SUPERFAMILY SSF56801 353 611 8.24E-113 T 23-04-2016 DC74_RS33035 9de3bb1fc5050ba4633f4051748e13f2 613 ProSitePatterns PS00455 Putative AMP-binding domain signature. 198 209 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS33035 9de3bb1fc5050ba4633f4051748e13f2 613 PANTHER PTHR24096 5 612 1.0E-149 T 23-04-2016 DC74_RS33035 9de3bb1fc5050ba4633f4051748e13f2 613 Gene3D G3DSA:3.40.50.980 14 204 3.8E-31 T 23-04-2016 DC74_RS33035 9de3bb1fc5050ba4633f4051748e13f2 613 Gene3D G3DSA:2.30.38.10 420 477 2.6E-15 T 23-04-2016 DC74_RS33035 9de3bb1fc5050ba4633f4051748e13f2 613 Gene3D G3DSA:3.30.300.30 480 602 1.8E-7 T 23-04-2016 DC74_RS33035 9de3bb1fc5050ba4633f4051748e13f2 613 Pfam PF00501 AMP-binding enzyme 22 483 4.0E-85 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS33035 9de3bb1fc5050ba4633f4051748e13f2 613 Gene3D G3DSA:3.40.50.980 350 415 3.5E-29 T 23-04-2016 DC74_RS33035 9de3bb1fc5050ba4633f4051748e13f2 613 Gene3D G3DSA:3.40.50.980 205 296 3.5E-29 T 23-04-2016 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 SUPERFAMILY SSF52029 184 374 2.09E-82 T 23-04-2016 IPR027409 GroEL-like apical domain DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 SUPERFAMILY SSF48592 6 133 3.08E-75 T 23-04-2016 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 SUPERFAMILY SSF48592 404 518 3.08E-75 T 23-04-2016 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 Gene3D G3DSA:3.50.7.10 195 368 3.9E-92 T 23-04-2016 IPR027409 GroEL-like apical domain DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.9E-97 T 23-04-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 PANTHER PTHR11353 1 541 4.6E-219 T 23-04-2016 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 9.9E-249 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 PRINTS PR00298 60kDa chaperonin signature 26 52 3.8E-70 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 PRINTS PR00298 60kDa chaperonin signature 82 109 3.8E-70 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 PRINTS PR00298 60kDa chaperonin signature 266 289 3.8E-70 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 PRINTS PR00298 60kDa chaperonin signature 396 417 3.8E-70 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 PRINTS PR00298 60kDa chaperonin signature 348 373 3.8E-70 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 23-04-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 41.505 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 SUPERFAMILY SSF54849 136 202 8.93E-27 T 23-04-2016 DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 Gene3D G3DSA:1.10.560.10 369 515 1.8E-39 T 23-04-2016 IPR027413 GroEL-like equatorial domain DC74_RS23545 74f035f320315296345c28ad6f8cf3d2 541 Gene3D G3DSA:1.10.560.10 6 194 4.1E-48 T 23-04-2016 IPR027413 GroEL-like equatorial domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SMART SM00824 Thioesterase 2124 2336 1.6E-71 T 23-04-2016 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Gene3D G3DSA:3.40.50.720 1512 1607 5.4E-15 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 280 3.5E-86 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Gene3D G3DSA:3.40.47.10 294 457 3.1E-64 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Gene3D G3DSA:3.40.47.10 30 292 1.1E-90 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SMART SM00829 1377 1678 2.0E-102 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Pfam PF00107 Zinc-binding dehydrogenase 1516 1607 2.5E-10 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Gene3D G3DSA:3.90.180.10 1390 1511 2.1E-32 T 23-04-2016 IPR011032 GroES-like DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 193 209 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 408 516 5.3E-13 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Pfam PF14765 Polyketide synthase dehydratase 906 1167 6.3E-50 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 PANTHER PTHR11712:SF242 2318 2330 0.0 T 23-04-2016 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 PANTHER PTHR11712:SF242 6 2038 0.0 T 23-04-2016 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SUPERFAMILY SSF53474 2000 2038 2.23E-26 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SUPERFAMILY SSF53474 2099 2336 2.23E-26 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 553 839 6.0E-124 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1397 1452 8.0E-6 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SMART SM00823 Phosphopantetheine attachment site 1970 2042 3.3E-26 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 288 405 4.6E-45 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Gene3D G3DSA:3.40.50.1820 2069 2338 9.8E-49 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Pfam PF08990 Erythronolide synthase docking 3 27 3.4E-11 T 23-04-2016 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 PANTHER PTHR11712 2318 2330 0.0 T 23-04-2016 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 PANTHER PTHR11712 6 2038 0.0 T 23-04-2016 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SUPERFAMILY SSF51735 1477 1649 3.56E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Pfam PF00975 Thioesterase domain 2128 2232 4.5E-10 T 23-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Gene3D G3DSA:1.10.1200.10 1966 2042 2.0E-19 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SUPERFAMILY SSF47336 1964 2053 7.36E-18 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SUPERFAMILY SSF50129 1390 1510 1.89E-26 T 23-04-2016 IPR011032 GroES-like DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SMART SM01294 1971 2038 0.0019 T 23-04-2016 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Pfam PF00698 Acyl transferase domain 553 857 3.2E-61 T 23-04-2016 IPR014043 Acyl transferase DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1997 2012 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SUPERFAMILY SSF51735 1184 1354 3.05E-25 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Pfam PF08659 KR domain 1688 1866 7.6E-60 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Gene3D G3DSA:3.40.50.720 1687 1870 3.2E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Gene3D G3DSA:3.30.70.250 671 731 3.2E-7 T 23-04-2016 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SUPERFAMILY SSF53901 31 404 4.98E-101 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Pfam PF00550 Phosphopantetheine attachment site 1972 2038 1.7E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SUPERFAMILY SSF55048 671 732 5.23E-11 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1688 1868 5.8E-61 T 23-04-2016 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SUPERFAMILY SSF52151 549 672 2.38E-74 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SUPERFAMILY SSF52151 733 830 2.38E-74 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SMART SM00825 Beta-ketoacyl synthase 36 458 2.8E-215 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Gene3D G3DSA:3.40.366.10 547 666 1.0E-79 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 Gene3D G3DSA:3.40.366.10 732 841 1.0E-79 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SMART SM00826 906 1063 6.5E-74 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS06825 be37a3968bc555367c00c8d972c1f707 2342 SUPERFAMILY SSF51735 1680 1898 3.12E-47 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 3.3E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 3.3E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 3.3E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 3.3E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.3E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 Gene3D G3DSA:3.40.50.720 4 246 1.0E-60 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 PANTHER PTHR24322 8 133 5.1E-81 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 Pfam PF00106 short chain dehydrogenase 7 189 2.6E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 PANTHER PTHR24322:SF386 149 181 5.1E-81 T 23-04-2016 DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 SUPERFAMILY SSF51735 4 243 3.4E-58 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 PANTHER PTHR24322 149 181 5.1E-81 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 PANTHER PTHR24322:SF386 8 133 5.1E-81 T 23-04-2016 DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 4.2E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 4.2E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05665 8a7f38c89e3ed32037927fe8a3f89165 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 4.2E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08300 e010ca229a1946413c6c3d66d890c1df 247 PANTHER PTHR34698:SF2 13 221 7.5E-77 T 23-04-2016 DC74_RS08300 e010ca229a1946413c6c3d66d890c1df 247 Pfam PF02682 Allophanate hydrolase subunit 1 20 209 1.0E-62 T 23-04-2016 IPR003833 Carboxyltransferase domain, subdomain C and D DC74_RS08300 e010ca229a1946413c6c3d66d890c1df 247 SUPERFAMILY SSF50891 98 222 2.24E-43 T 23-04-2016 IPR029000 Cyclophilin-like domain DC74_RS08300 e010ca229a1946413c6c3d66d890c1df 247 SMART SM00796 18 209 3.8E-79 T 23-04-2016 IPR003833 Carboxyltransferase domain, subdomain C and D DC74_RS08300 e010ca229a1946413c6c3d66d890c1df 247 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 24 218 4.2E-47 T 23-04-2016 IPR010016 KipI family DC74_RS08300 e010ca229a1946413c6c3d66d890c1df 247 PANTHER PTHR34698 13 221 7.5E-77 T 23-04-2016 DC74_RS08300 e010ca229a1946413c6c3d66d890c1df 247 Gene3D G3DSA:2.40.100.10 97 222 8.2E-52 T 23-04-2016 IPR029000 Cyclophilin-like domain DC74_RS30930 4ce739b9db57f2891ecc23c2d25a376b 401 PANTHER PTHR10566 94 198 9.2E-46 T 23-04-2016 DC74_RS30930 4ce739b9db57f2891ecc23c2d25a376b 401 SUPERFAMILY SSF56601 10 391 1.13E-77 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS30930 4ce739b9db57f2891ecc23c2d25a376b 401 PANTHER PTHR10566:SF94 94 198 9.2E-46 T 23-04-2016 DC74_RS30930 4ce739b9db57f2891ecc23c2d25a376b 401 Pfam PF00144 Beta-lactamase 22 385 4.5E-75 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS30930 4ce739b9db57f2891ecc23c2d25a376b 401 Gene3D G3DSA:3.40.710.10 11 394 2.5E-87 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 Gene3D G3DSA:3.40.50.720 238 370 6.4E-25 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 SUPERFAMILY SSF51735 204 398 2.75E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 119 196 7.9E-6 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 Pfam PF00107 Zinc-binding dehydrogenase 242 386 4.0E-39 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 SMART SM00829 55 421 4.7E-11 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 Gene3D G3DSA:3.90.180.10 53 237 1.9E-30 T 23-04-2016 IPR011032 GroES-like DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 37 434 5.0E-181 T 23-04-2016 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 SUPERFAMILY SSF50129 45 236 6.29E-28 T 23-04-2016 IPR011032 GroES-like DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 PANTHER PTHR11695 60 100 6.1E-91 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 PANTHER PTHR11695 119 151 6.1E-91 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 PANTHER PTHR11695 170 280 6.1E-91 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 PANTHER PTHR11695 297 433 6.1E-91 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 PANTHER PTHR11695:SF294 60 100 6.1E-91 T 23-04-2016 DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 PANTHER PTHR11695:SF294 119 151 6.1E-91 T 23-04-2016 DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 PANTHER PTHR11695:SF294 170 280 6.1E-91 T 23-04-2016 DC74_RS06875 836fb3a35954afedb3318b42c69efef9 449 PANTHER PTHR11695:SF294 297 433 6.1E-91 T 23-04-2016 DC74_RS15720 f431953a3f02530b34db3232ec1300f3 323 SUPERFAMILY SSF51735 2 139 1.22E-32 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15720 f431953a3f02530b34db3232ec1300f3 323 SUPERFAMILY SSF55347 119 269 1.8E-10 T 23-04-2016 DC74_RS15720 f431953a3f02530b34db3232ec1300f3 323 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 112 5.1E-18 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 DC74_RS15720 f431953a3f02530b34db3232ec1300f3 323 Gene3D G3DSA:3.40.50.720 1 133 1.1E-31 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15720 f431953a3f02530b34db3232ec1300f3 323 Gene3D G3DSA:3.30.360.10 134 250 5.2E-30 T 23-04-2016 DC74_RS15720 f431953a3f02530b34db3232ec1300f3 323 Hamap MF_01671 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase [iolG]. 1 323 45.014 T 23-04-2016 IPR023794 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase GO:0019310|GO:0050112|GO:0055114 KEGG: 00521+1.1.1.18|KEGG: 00562+1.1.1.18|MetaCyc: PWY-5940|MetaCyc: PWY-7237|MetaCyc: PWY-7241 DC74_RS15720 f431953a3f02530b34db3232ec1300f3 323 PANTHER PTHR22604:SF103 1 323 3.0E-141 T 23-04-2016 DC74_RS15720 f431953a3f02530b34db3232ec1300f3 323 PANTHER PTHR22604 1 323 3.0E-141 T 23-04-2016 DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 SUPERFAMILY SSF52540 20 243 4.53E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 PANTHER PTHR23115 71 319 5.1E-61 T 23-04-2016 DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 PANTHER PTHR23115 22 55 5.1E-61 T 23-04-2016 DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 SUPERFAMILY SSF50465 327 428 1.58E-23 T 23-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 21 428 3.0E-165 T 23-04-2016 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 Gene3D G3DSA:2.40.30.10 232 360 2.0E-20 T 23-04-2016 DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 Pfam PF00009 Elongation factor Tu GTP binding domain 21 204 2.9E-40 T 23-04-2016 DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 74 89 - T 23-04-2016 IPR031157 Tr-type G domain, conserved site DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 PRINTS PR00315 GTP-binding elongation factor signature 22 35 2.6E-12 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 PRINTS PR00315 GTP-binding elongation factor signature 154 163 2.6E-12 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 PRINTS PR00315 GTP-binding elongation factor signature 81 89 2.6E-12 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 PRINTS PR00315 GTP-binding elongation factor signature 117 128 2.6E-12 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 PRINTS PR00315 GTP-binding elongation factor signature 101 111 2.6E-12 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 SUPERFAMILY SSF50447 231 321 4.48E-19 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS30840 37d5410ca699322801f6b9befbcbcd03 453 Gene3D G3DSA:3.40.50.300 19 225 2.9E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23830 1664798b40dec6229beed45bd3afd822 448 SUPERFAMILY SSF56176 4 188 8.88E-43 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS23830 1664798b40dec6229beed45bd3afd822 448 Gene3D G3DSA:3.30.465.10 80 187 3.4E-12 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS23830 1664798b40dec6229beed45bd3afd822 448 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 24 57 - T 23-04-2016 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 DC74_RS23830 1664798b40dec6229beed45bd3afd822 448 PANTHER PTHR11748 1 280 9.4E-55 T 23-04-2016 DC74_RS23830 1664798b40dec6229beed45bd3afd822 448 Gene3D G3DSA:3.30.43.10 21 79 3.9E-7 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS23830 1664798b40dec6229beed45bd3afd822 448 Pfam PF01565 FAD binding domain 24 156 1.3E-25 T 23-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DC74_RS36440 039e08cea8b0b549bcaa74e407c3ee3f 162 SMART SM00903 14 158 1.9E-52 T 23-04-2016 IPR002563 Flavin reductase like domain GO:0010181 DC74_RS36440 039e08cea8b0b549bcaa74e407c3ee3f 162 SUPERFAMILY SSF50475 5 157 1.47E-45 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS36440 039e08cea8b0b549bcaa74e407c3ee3f 162 Pfam PF01613 Flavin reductase like domain 15 158 3.7E-35 T 23-04-2016 IPR002563 Flavin reductase like domain GO:0010181 DC74_RS36440 039e08cea8b0b549bcaa74e407c3ee3f 162 PANTHER PTHR30466 5 156 1.8E-33 T 23-04-2016 DC74_RS36440 039e08cea8b0b549bcaa74e407c3ee3f 162 Gene3D G3DSA:2.30.110.10 5 157 1.7E-52 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS09575 db05e3f6365e039f7e50b4a7088e10ff 276 SUPERFAMILY SSF50891 107 272 8.86E-33 T 23-04-2016 IPR029000 Cyclophilin-like domain DC74_RS09575 db05e3f6365e039f7e50b4a7088e10ff 276 PANTHER PTHR11071:SF165 24 250 5.0E-45 T 23-04-2016 DC74_RS09575 db05e3f6365e039f7e50b4a7088e10ff 276 PANTHER PTHR11071 24 250 5.0E-45 T 23-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 DC74_RS09575 db05e3f6365e039f7e50b4a7088e10ff 276 Gene3D G3DSA:2.40.100.10 102 273 8.6E-33 T 23-04-2016 IPR029000 Cyclophilin-like domain DC74_RS09575 db05e3f6365e039f7e50b4a7088e10ff 276 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 110 269 1.1E-25 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 SUPERFAMILY SSF52172 1 129 7.97E-28 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.4E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.4E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.4E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 SMART SM00448 1 114 6.1E-20 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 Gene3D G3DSA:3.40.50.2300 1 119 1.3E-29 T 23-04-2016 DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 SMART SM00421 153 210 1.8E-24 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 PANTHER PTHR26402:SF564 1 219 4.9E-78 T 23-04-2016 DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 Pfam PF00072 Response regulator receiver domain 1 115 6.6E-23 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 PANTHER PTHR26402 1 219 4.9E-78 T 23-04-2016 DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 SUPERFAMILY SSF46894 150 216 5.1E-21 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 Gene3D G3DSA:1.10.10.10 120 216 2.2E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06895 551102cf98e1968094aaf64363c5af87 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.9E-17 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 Pfam PF13740 ACT domain 19 92 2.2E-5 T 23-04-2016 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 SUPERFAMILY SSF55021 17 97 2.0E-20 T 23-04-2016 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 PANTHER PTHR10520:SF7 14 289 9.9E-157 T 23-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 19 295 6.2E-103 T 23-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 Gene3D G3DSA:3.30.70.260 15 96 5.7E-31 T 23-04-2016 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 247 269 3.107916E-51 T 23-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 101 123 3.107916E-51 T 23-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 20 46 3.107916E-51 T 23-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 269 294 3.107916E-51 T 23-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 52 64 3.107916E-51 T 23-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 123 150 3.107916E-51 T 23-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 15 295 47.997 T 23-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 PIRSF PIRSF036480 15 296 3.7E-114 T 23-04-2016 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 Gene3D G3DSA:3.40.50.170 100 294 2.3E-55 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 Pfam PF00551 Formyl transferase 100 277 6.6E-37 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 PANTHER PTHR10520 14 289 9.9E-157 T 23-04-2016 DC74_RS23975 fc53e4ceba2e974adafdbce10261e38e 296 SUPERFAMILY SSF53328 100 295 4.19E-62 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 Hamap MF_00259 Aminomethyltransferase [gcvT]. 4 370 44.773 T 23-04-2016 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 Gene3D G3DSA:2.40.30.110 288 372 1.6E-29 T 23-04-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 PANTHER PTHR13847 6 367 8.2E-53 T 23-04-2016 DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 PANTHER PTHR13847:SF5 6 367 8.2E-53 T 23-04-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 SUPERFAMILY SSF101790 282 371 4.41E-25 T 23-04-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 Gene3D G3DSA:3.30.1360.120 144 238 2.0E-54 T 23-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 Gene3D G3DSA:3.30.1360.120 6 55 2.0E-54 T 23-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 6 370 1.4E-106 T 23-04-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 Pfam PF01571 Aminomethyltransferase folate-binding domain 11 260 1.7E-91 T 23-04-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 268 364 2.4E-25 T 23-04-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 SUPERFAMILY SSF103025 6 280 7.06E-96 T 23-04-2016 DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 PIRSF PIRSF006487 1 372 1.3E-100 T 23-04-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 DC74_RS27470 01b2db144ae876f1dbb27dc59c2c9023 372 Gene3D G3DSA:3.30.70.1400 56 143 1.4E-26 T 23-04-2016 DC74_RS22010 e67963050842d0cf9e583288edcfab9d 729 SUPERFAMILY SSF53955 63 286 1.07E-68 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS22010 e67963050842d0cf9e583288edcfab9d 729 Gene3D G3DSA:3.40.710.10 264 700 1.8E-110 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS22010 e67963050842d0cf9e583288edcfab9d 729 PANTHER PTHR32282:SF0 1 682 2.8E-184 T 23-04-2016 DC74_RS22010 e67963050842d0cf9e583288edcfab9d 729 Pfam PF00912 Transglycosylase 78 261 7.5E-62 T 23-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 DC74_RS22010 e67963050842d0cf9e583288edcfab9d 729 SUPERFAMILY SSF56601 243 265 1.22E-96 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS22010 e67963050842d0cf9e583288edcfab9d 729 SUPERFAMILY SSF56601 299 675 1.22E-96 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS22010 e67963050842d0cf9e583288edcfab9d 729 Gene3D G3DSA:1.10.3810.10 77 263 1.2E-69 T 23-04-2016 DC74_RS22010 e67963050842d0cf9e583288edcfab9d 729 Pfam PF00905 Penicillin binding protein transpeptidase domain 361 626 7.8E-34 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS22010 e67963050842d0cf9e583288edcfab9d 729 PANTHER PTHR32282 1 682 2.8E-184 T 23-04-2016 DC74_RS27755 f90d6d03e586915297a3cab7c4aed7c2 235 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 101 8.0E-32 T 23-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27755 f90d6d03e586915297a3cab7c4aed7c2 235 Pfam PF00699 Urease beta subunit 128 208 1.2E-27 T 23-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27755 f90d6d03e586915297a3cab7c4aed7c2 235 Gene3D G3DSA:2.10.150.10 126 233 1.7E-35 T 23-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27755 f90d6d03e586915297a3cab7c4aed7c2 235 Pfam PF00547 Urease, gamma subunit 1 99 4.9E-36 T 23-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27755 f90d6d03e586915297a3cab7c4aed7c2 235 PIRSF PIRSF001225 1 231 3.5E-81 T 23-04-2016 IPR008223 Urease, gamma-beta subunit GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27755 f90d6d03e586915297a3cab7c4aed7c2 235 PANTHER PTHR33569 2 235 3.7E-96 T 23-04-2016 DC74_RS27755 f90d6d03e586915297a3cab7c4aed7c2 235 Gene3D G3DSA:3.30.280.10 1 99 1.5E-36 T 23-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27755 f90d6d03e586915297a3cab7c4aed7c2 235 SUPERFAMILY SSF51278 114 233 1.57E-35 T 23-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27755 f90d6d03e586915297a3cab7c4aed7c2 235 SUPERFAMILY SSF54111 1 101 9.16E-33 T 23-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27755 f90d6d03e586915297a3cab7c4aed7c2 235 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 31 99 6.0E-28 T 23-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27755 f90d6d03e586915297a3cab7c4aed7c2 235 PANTHER PTHR33569:SF1 2 235 3.7E-96 T 23-04-2016 DC74_RS34255 764923222af6583d32f010d1200250a5 160 Gene3D G3DSA:3.30.70.920 55 148 1.2E-22 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS34255 764923222af6583d32f010d1200250a5 160 Gene3D G3DSA:1.10.10.10 2 53 2.6E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34255 764923222af6583d32f010d1200250a5 160 Pfam PF01037 Lrp/AsnC ligand binding domain 69 138 8.3E-20 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS34255 764923222af6583d32f010d1200250a5 160 SUPERFAMILY SSF54909 64 148 2.41E-20 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS34255 764923222af6583d32f010d1200250a5 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 3.6E-10 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS34255 764923222af6583d32f010d1200250a5 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 3.6E-10 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS34255 764923222af6583d32f010d1200250a5 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 3.6E-10 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS34255 764923222af6583d32f010d1200250a5 160 SMART SM00344 3 109 5.8E-31 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS34255 764923222af6583d32f010d1200250a5 160 PANTHER PTHR30154:SF12 1 154 4.5E-55 T 23-04-2016 DC74_RS34255 764923222af6583d32f010d1200250a5 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 2.9E-13 T 23-04-2016 DC74_RS34255 764923222af6583d32f010d1200250a5 160 PANTHER PTHR30154 1 154 4.5E-55 T 23-04-2016 DC74_RS34255 764923222af6583d32f010d1200250a5 160 SUPERFAMILY SSF46785 3 86 1.59E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14090 6f95f37b44c7ceff69064440381554a5 305 PANTHER PTHR32196 31 295 1.2E-84 T 23-04-2016 DC74_RS14090 6f95f37b44c7ceff69064440381554a5 305 Gene3D G3DSA:3.40.50.2300 28 144 6.3E-37 T 23-04-2016 DC74_RS14090 6f95f37b44c7ceff69064440381554a5 305 SUPERFAMILY SSF53822 5 303 9.82E-89 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS14090 6f95f37b44c7ceff69064440381554a5 305 Pfam PF13407 Periplasmic binding protein domain 31 282 4.3E-61 T 23-04-2016 IPR025997 Periplasmic binding protein DC74_RS14090 6f95f37b44c7ceff69064440381554a5 305 PANTHER PTHR32196:SF9 31 295 1.2E-84 T 23-04-2016 DC74_RS14090 6f95f37b44c7ceff69064440381554a5 305 Gene3D G3DSA:3.40.50.2300 145 302 1.0E-57 T 23-04-2016 DC74_RS21505 245fc4a9003831cfaf567ce59ce2bf16 774 PANTHER PTHR33908 496 695 1.3E-91 T 23-04-2016 DC74_RS21505 245fc4a9003831cfaf567ce59ce2bf16 774 PANTHER PTHR33908 315 466 1.3E-91 T 23-04-2016 DC74_RS21505 245fc4a9003831cfaf567ce59ce2bf16 774 PANTHER PTHR33908 26 298 1.3E-91 T 23-04-2016 DC74_RS21505 245fc4a9003831cfaf567ce59ce2bf16 774 PANTHER PTHR33908:SF3 496 695 1.3E-91 T 23-04-2016 DC74_RS21505 245fc4a9003831cfaf567ce59ce2bf16 774 PANTHER PTHR33908:SF3 315 466 1.3E-91 T 23-04-2016 DC74_RS21505 245fc4a9003831cfaf567ce59ce2bf16 774 PANTHER PTHR33908:SF3 26 298 1.3E-91 T 23-04-2016 DC74_RS21505 245fc4a9003831cfaf567ce59ce2bf16 774 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 97 255 2.2E-30 T 23-04-2016 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 Pfam PF00689 Cation transporting ATPase, C-terminus 745 910 1.6E-13 T 23-04-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 SMART SM00831 42 112 6.2E-15 T 23-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 383 389 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 SUPERFAMILY SSF56784 551 703 3.31E-37 T 23-04-2016 IPR023214 HAD-like domain DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 244 417 1.0E-21 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 630 749 5.4E-27 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 PANTHER PTHR24093:SF128 20 920 0.0 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 Pfam PF00702 haloacid dehalogenase-like hydrolase 377 675 2.0E-19 T 23-04-2016 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 SUPERFAMILY SSF81660 348 564 5.17E-40 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 PANTHER PTHR24093 20 920 0.0 T 23-04-2016 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 Pfam PF00690 Cation transporter/ATPase, N-terminus 45 109 1.0E-15 T 23-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 32 920 0.0 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 SUPERFAMILY SSF81665 282 375 2.75E-92 T 23-04-2016 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 SUPERFAMILY SSF81665 43 161 2.75E-92 T 23-04-2016 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 SUPERFAMILY SSF81665 710 918 2.75E-92 T 23-04-2016 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 SUPERFAMILY SSF81653 177 280 2.22E-22 T 23-04-2016 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 Pfam PF00122 E1-E2 ATPase 129 372 4.8E-50 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 Gene3D G3DSA:1.20.1110.10 630 910 2.5E-59 T 23-04-2016 IPR023298 P-type ATPase, transmembrane domain DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 Gene3D G3DSA:1.20.1110.10 95 155 2.5E-59 T 23-04-2016 IPR023298 P-type ATPase, transmembrane domain DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 PRINTS PR01836 Magnesium-transporting ATPase signature 719 734 3.2E-78 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 PRINTS PR01836 Magnesium-transporting ATPase signature 789 805 3.2E-78 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 PRINTS PR01836 Magnesium-transporting ATPase signature 824 845 3.2E-78 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 PRINTS PR01836 Magnesium-transporting ATPase signature 415 428 3.2E-78 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 PRINTS PR01836 Magnesium-transporting ATPase signature 311 330 3.2E-78 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 PRINTS PR01836 Magnesium-transporting ATPase signature 737 748 3.2E-78 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 PRINTS PR01836 Magnesium-transporting ATPase signature 294 310 3.2E-78 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 PRINTS PR01836 Magnesium-transporting ATPase signature 769 782 3.2E-78 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 PRINTS PR01836 Magnesium-transporting ATPase signature 874 895 3.2E-78 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 Gene3D G3DSA:3.40.1110.10 373 568 2.0E-37 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 Gene3D G3DSA:2.70.150.10 60 94 2.1E-27 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS31180 66fac86857a1c7a0d20eb5fb775a6093 921 Gene3D G3DSA:2.70.150.10 156 280 2.1E-27 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS39905 0cd396ee5954b25fe51f08788caacbc4 224 Gene3D G3DSA:1.10.3210.10 33 129 5.5E-8 T 23-04-2016 IPR006674 HD domain DC74_RS39905 0cd396ee5954b25fe51f08788caacbc4 224 SMART SM00471 32 176 0.0012 T 23-04-2016 IPR003607 HD/PDEase domain DC74_RS39905 0cd396ee5954b25fe51f08788caacbc4 224 SUPERFAMILY SSF109604 15 143 7.71E-16 T 23-04-2016 DC74_RS39905 0cd396ee5954b25fe51f08788caacbc4 224 PANTHER PTHR35569 3 224 3.9E-31 T 23-04-2016 DC74_RS39905 0cd396ee5954b25fe51f08788caacbc4 224 Pfam PF01966 HD domain 36 142 2.7E-7 T 23-04-2016 IPR006674 HD domain DC74_RS27415 00487503905e70d064650dbb1d4f1ea2 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 237 8.5E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS27415 00487503905e70d064650dbb1d4f1ea2 240 Pfam PF00072 Response regulator receiver domain 1 110 9.1E-31 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS27415 00487503905e70d064650dbb1d4f1ea2 240 PANTHER PTHR26402 1 121 9.1E-85 T 23-04-2016 DC74_RS27415 00487503905e70d064650dbb1d4f1ea2 240 SMART SM00448 1 110 1.1E-38 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS27415 00487503905e70d064650dbb1d4f1ea2 240 SUPERFAMILY SSF46894 139 238 1.5E-26 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS27415 00487503905e70d064650dbb1d4f1ea2 240 PANTHER PTHR26402:SF556 139 240 9.1E-85 T 23-04-2016 DC74_RS27415 00487503905e70d064650dbb1d4f1ea2 240 PANTHER PTHR26402:SF556 1 121 9.1E-85 T 23-04-2016 DC74_RS27415 00487503905e70d064650dbb1d4f1ea2 240 SMART SM00862 162 237 4.5E-23 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS27415 00487503905e70d064650dbb1d4f1ea2 240 Gene3D G3DSA:1.10.10.10 139 239 1.6E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27415 00487503905e70d064650dbb1d4f1ea2 240 PANTHER PTHR26402 139 240 9.1E-85 T 23-04-2016 DC74_RS27415 00487503905e70d064650dbb1d4f1ea2 240 Gene3D G3DSA:3.40.50.2300 1 122 1.0E-42 T 23-04-2016 DC74_RS27415 00487503905e70d064650dbb1d4f1ea2 240 SUPERFAMILY SSF52172 1 118 5.98E-41 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS14200 a6c5b8ea23ab9c519309a633676e2c6f 137 PRINTS PR00421 Thioredoxin family signature 68 79 2.2E-7 T 23-04-2016 DC74_RS14200 a6c5b8ea23ab9c519309a633676e2c6f 137 PRINTS PR00421 Thioredoxin family signature 29 38 2.2E-7 T 23-04-2016 DC74_RS14200 a6c5b8ea23ab9c519309a633676e2c6f 137 PRINTS PR00421 Thioredoxin family signature 21 29 2.2E-7 T 23-04-2016 DC74_RS14200 a6c5b8ea23ab9c519309a633676e2c6f 137 Gene3D G3DSA:3.40.30.10 3 101 1.0E-30 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS14200 a6c5b8ea23ab9c519309a633676e2c6f 137 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 23-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 DC74_RS14200 a6c5b8ea23ab9c519309a633676e2c6f 137 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 9.7E-31 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DC74_RS14200 a6c5b8ea23ab9c519309a633676e2c6f 137 PANTHER PTHR10438:SF266 4 128 1.9E-41 T 23-04-2016 DC74_RS14200 a6c5b8ea23ab9c519309a633676e2c6f 137 SUPERFAMILY SSF52833 3 102 1.01E-30 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS14200 a6c5b8ea23ab9c519309a633676e2c6f 137 Pfam PF00085 Thioredoxin 3 100 1.6E-25 T 23-04-2016 IPR013766 Thioredoxin domain GO:0045454 DC74_RS14200 a6c5b8ea23ab9c519309a633676e2c6f 137 PANTHER PTHR10438 4 128 1.9E-41 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 270 345 3.0E-23 T 23-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 PANTHER PTHR13779:SF25 12 350 1.6E-162 T 23-04-2016 DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 22 253 4.6E-109 T 23-04-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 42 344 4.8E-135 T 23-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 271 344 2.0E-29 T 23-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 362 162.654 T 23-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 Gene3D G3DSA:3.40.50.300 38 83 6.1E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 PANTHER PTHR13779 12 350 1.6E-162 T 23-04-2016 DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 SUPERFAMILY SSF52540 38 269 2.6E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 Gene3D G3DSA:1.10.10.10 275 345 5.6E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 Gene3D G3DSA:3.40.50.300 84 206 1.9E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 SUPERFAMILY SSF46785 275 348 6.26E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 SMART SM00382 69 202 5.2E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS09610 413c7d7be864011b748faf1c7f2619b7 362 Gene3D G3DSA:1.10.8.60 207 273 2.1E-32 T 23-04-2016 DC74_RS38920 1c0a4aedadd7a675c4be87bbef75f7d7 208 PANTHER PTHR11002 9 200 2.0E-67 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS38920 1c0a4aedadd7a675c4be87bbef75f7d7 208 SUPERFAMILY SSF53056 3 200 1.2E-47 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS38920 1c0a4aedadd7a675c4be87bbef75f7d7 208 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 54 61 - T 23-04-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS38920 1c0a4aedadd7a675c4be87bbef75f7d7 208 Pfam PF00484 Carbonic anhydrase 49 196 2.4E-32 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS38920 1c0a4aedadd7a675c4be87bbef75f7d7 208 Gene3D G3DSA:3.40.1050.10 8 201 9.8E-45 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS38920 1c0a4aedadd7a675c4be87bbef75f7d7 208 PANTHER PTHR11002:SF17 9 200 2.0E-67 T 23-04-2016 DC74_RS38920 1c0a4aedadd7a675c4be87bbef75f7d7 208 SMART SM00947 42 201 4.8E-40 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS29465 55679147a8441d9371736548845ca1a2 256 Gene3D G3DSA:3.40.50.720 2 241 1.1E-68 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29465 55679147a8441d9371736548845ca1a2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 9.3E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS29465 55679147a8441d9371736548845ca1a2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 9.3E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS29465 55679147a8441d9371736548845ca1a2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 9.3E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS29465 55679147a8441d9371736548845ca1a2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 9.3E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS29465 55679147a8441d9371736548845ca1a2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 9.3E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS29465 55679147a8441d9371736548845ca1a2 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 9.3E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS29465 55679147a8441d9371736548845ca1a2 256 SUPERFAMILY SSF51735 2 239 1.76E-67 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29465 55679147a8441d9371736548845ca1a2 256 PANTHER PTHR24322 149 184 1.8E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS29465 55679147a8441d9371736548845ca1a2 256 PANTHER PTHR24322 6 132 1.8E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS29465 55679147a8441d9371736548845ca1a2 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS29465 55679147a8441d9371736548845ca1a2 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 237 7.3E-54 T 23-04-2016 DC74_RS29465 55679147a8441d9371736548845ca1a2 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 7.3E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS29465 55679147a8441d9371736548845ca1a2 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 7.3E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS29465 55679147a8441d9371736548845ca1a2 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 7.3E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36435 c78ce9075edb2780ec9173a48c2363c7 298 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 247 268 - T 23-04-2016 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 DC74_RS36435 c78ce9075edb2780ec9173a48c2363c7 298 Gene3D G3DSA:3.10.180.10 135 297 5.5E-49 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS36435 c78ce9075edb2780ec9173a48c2363c7 298 SUPERFAMILY SSF54593 1 127 8.11E-20 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS36435 c78ce9075edb2780ec9173a48c2363c7 298 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 143 269 1.3E-21 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS36435 c78ce9075edb2780ec9173a48c2363c7 298 SUPERFAMILY SSF54593 142 296 2.28E-33 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS36435 c78ce9075edb2780ec9173a48c2363c7 298 Gene3D G3DSA:3.10.180.10 1 128 2.3E-28 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 Gene3D G3DSA:3.40.50.620 351 568 2.4E-137 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 Gene3D G3DSA:3.40.50.620 18 206 2.4E-137 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 Gene3D G3DSA:1.10.730.10 571 754 5.7E-56 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 Pfam PF08264 Anticodon-binding domain of tRNA 612 762 3.8E-36 T 23-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 SUPERFAMILY SSF50677 204 344 1.16E-51 T 23-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 Hamap MF_02004 Valine--tRNA ligase [valS]. 15 880 15.134 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 Gene3D G3DSA:1.10.287.380 808 878 1.2E-6 T 23-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 815 879 4.0E-14 T 23-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 PANTHER PTHR11946 6 873 0.0 T 23-04-2016 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 TIGRFAM TIGR00422 valS: valine--tRNA ligase 16 859 3.8E-303 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 PRINTS PR00986 Valyl-tRNA synthetase signature 356 369 1.4E-37 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 PRINTS PR00986 Valyl-tRNA synthetase signature 481 499 1.4E-37 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 PRINTS PR00986 Valyl-tRNA synthetase signature 450 471 1.4E-37 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 PRINTS PR00986 Valyl-tRNA synthetase signature 49 60 1.4E-37 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 PRINTS PR00986 Valyl-tRNA synthetase signature 241 258 1.4E-37 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 566 8.5E-189 T 23-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 SUPERFAMILY SSF46589 815 879 1.57E-12 T 23-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 PANTHER PTHR11946:SF5 6 873 0.0 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 SUPERFAMILY SSF47323 582 828 3.36E-50 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 56 67 - T 23-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 Gene3D G3DSA:3.90.740.10 207 344 3.6E-44 T 23-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 SUPERFAMILY SSF52374 351 580 2.95E-134 T 23-04-2016 DC74_RS15305 dc5aab938181cd6f8affea41aebe051b 882 SUPERFAMILY SSF52374 15 205 2.95E-134 T 23-04-2016 DC74_RS19300 c09a318d80e4b4510517335170590d8f 609 PANTHER PTHR31566 9 428 2.7E-119 T 23-04-2016 DC74_RS19300 c09a318d80e4b4510517335170590d8f 609 PANTHER PTHR31566 444 589 2.7E-119 T 23-04-2016 DC74_RS19300 c09a318d80e4b4510517335170590d8f 609 PANTHER PTHR31566:SF0 9 428 2.7E-119 T 23-04-2016 DC74_RS19300 c09a318d80e4b4510517335170590d8f 609 PANTHER PTHR31566:SF0 444 589 2.7E-119 T 23-04-2016 DC74_RS19300 c09a318d80e4b4510517335170590d8f 609 Pfam PF05140 ResB-like family 57 559 4.2E-130 T 23-04-2016 IPR007816 ResB-like domain DC74_RS27160 86fd8ac503bb1a20290095ab89099965 319 SUPERFAMILY SSF52540 3 311 2.22E-76 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27160 86fd8ac503bb1a20290095ab89099965 319 Gene3D G3DSA:3.40.50.300 47 251 2.0E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27160 86fd8ac503bb1a20290095ab89099965 319 PANTHER PTHR23408 3 312 8.5E-104 T 23-04-2016 DC74_RS27160 86fd8ac503bb1a20290095ab89099965 319 PANTHER PTHR23408:SF3 3 312 8.5E-104 T 23-04-2016 DC74_RS27160 86fd8ac503bb1a20290095ab89099965 319 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 15 312 2.4E-104 T 23-04-2016 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 DC74_RS27160 86fd8ac503bb1a20290095ab89099965 319 Pfam PF03308 ArgK protein 20 280 2.2E-97 T 23-04-2016 DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PANTHER PTHR24322:SF328 155 187 1.1E-55 T 23-04-2016 DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PANTHER PTHR24322:SF328 10 139 1.1E-55 T 23-04-2016 DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.0E-14 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.0E-14 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.0E-14 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 Gene3D G3DSA:3.40.50.720 2 247 1.4E-84 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PANTHER PTHR24322 155 187 1.1E-55 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PANTHER PTHR24322 10 139 1.1E-55 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 177 1.5E-6 T 23-04-2016 DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 245 5.7E-62 T 23-04-2016 DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.7E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 2.7E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.7E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.7E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.7E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.7E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22855 2de96bb5be41b328fb2c2b2068234426 248 SUPERFAMILY SSF51735 5 246 1.09E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07935 9849c89781b469d0c5a5a64034e978ea 414 PANTHER PTHR24421 119 410 1.1E-80 T 23-04-2016 DC74_RS07935 9849c89781b469d0c5a5a64034e978ea 414 PANTHER PTHR24421:SF19 119 410 1.1E-80 T 23-04-2016 DC74_RS07935 9849c89781b469d0c5a5a64034e978ea 414 Pfam PF07730 Histidine kinase 220 286 2.4E-15 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS07935 9849c89781b469d0c5a5a64034e978ea 414 SUPERFAMILY SSF55874 296 408 2.56E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS07935 9849c89781b469d0c5a5a64034e978ea 414 Gene3D G3DSA:3.30.565.10 324 408 1.9E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS07935 9849c89781b469d0c5a5a64034e978ea 414 SMART SM00387 320 410 6.4E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS13285 0569ce85482df7a7e86e197477421d28 1007 SUPERFAMILY SSF81593 854 1005 1.49E-35 T 23-04-2016 DC74_RS13285 0569ce85482df7a7e86e197477421d28 1007 Gene3D G3DSA:3.30.460.10 174 334 1.2E-56 T 23-04-2016 DC74_RS13285 0569ce85482df7a7e86e197477421d28 1007 Gene3D G3DSA:3.30.460.10 689 848 1.5E-50 T 23-04-2016 DC74_RS13285 0569ce85482df7a7e86e197477421d28 1007 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 91 325 2.8E-51 T 23-04-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 DC74_RS13285 0569ce85482df7a7e86e197477421d28 1007 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 593 839 7.3E-41 T 23-04-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 DC74_RS13285 0569ce85482df7a7e86e197477421d28 1007 SUPERFAMILY SSF81301 565 848 9.81E-59 T 23-04-2016 DC74_RS13285 0569ce85482df7a7e86e197477421d28 1007 SUPERFAMILY SSF81301 74 334 5.89E-69 T 23-04-2016 DC74_RS13285 0569ce85482df7a7e86e197477421d28 1007 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 87 995 17.093 T 23-04-2016 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 DC74_RS13285 0569ce85482df7a7e86e197477421d28 1007 SUPERFAMILY SSF81593 340 489 6.59E-40 T 23-04-2016 DC74_RS13285 0569ce85482df7a7e86e197477421d28 1007 PANTHER PTHR30621 3 1006 2.5E-298 T 23-04-2016 DC74_RS13285 0569ce85482df7a7e86e197477421d28 1007 Pfam PF08335 GlnD PII-uridylyltransferase 862 1004 2.6E-20 T 23-04-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 DC74_RS13285 0569ce85482df7a7e86e197477421d28 1007 Pfam PF08335 GlnD PII-uridylyltransferase 348 488 1.9E-38 T 23-04-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 DC74_RS21075 ba96b15f5d0a3da064c358755ca8e8fe 305 PIRSF PIRSF007580 1 296 2.2E-119 T 23-04-2016 IPR016516 Uncharacterised conserved protein UCP07580 DC74_RS21075 ba96b15f5d0a3da064c358755ca8e8fe 305 Pfam PF10118 Predicted metal-dependent hydrolase 14 276 8.3E-77 T 23-04-2016 IPR016516 Uncharacterised conserved protein UCP07580 DC74_RS21075 ba96b15f5d0a3da064c358755ca8e8fe 305 PANTHER PTHR39456:SF1 1 299 1.8E-133 T 23-04-2016 DC74_RS21075 ba96b15f5d0a3da064c358755ca8e8fe 305 PANTHER PTHR39456 1 299 1.8E-133 T 23-04-2016 DC74_RS35425 475f25d52fd55eec9cef4cce1f8b6f8b 211 Gene3D G3DSA:3.90.226.10 10 197 9.8E-72 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS35425 475f25d52fd55eec9cef4cce1f8b6f8b 211 SUPERFAMILY SSF52096 17 199 1.13E-60 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS35425 475f25d52fd55eec9cef4cce1f8b6f8b 211 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 118 131 - T 23-04-2016 IPR033135 ClpP, histidine active site DC74_RS35425 475f25d52fd55eec9cef4cce1f8b6f8b 211 PRINTS PR00127 Clp protease catalytic subunit P signature 96 113 7.1E-42 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS35425 475f25d52fd55eec9cef4cce1f8b6f8b 211 PRINTS PR00127 Clp protease catalytic subunit P signature 25 40 7.1E-42 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS35425 475f25d52fd55eec9cef4cce1f8b6f8b 211 PRINTS PR00127 Clp protease catalytic subunit P signature 176 195 7.1E-42 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS35425 475f25d52fd55eec9cef4cce1f8b6f8b 211 PRINTS PR00127 Clp protease catalytic subunit P signature 117 136 7.1E-42 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS35425 475f25d52fd55eec9cef4cce1f8b6f8b 211 PRINTS PR00127 Clp protease catalytic subunit P signature 65 85 7.1E-42 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS35425 475f25d52fd55eec9cef4cce1f8b6f8b 211 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 9 201 38.12 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS35425 475f25d52fd55eec9cef4cce1f8b6f8b 211 PANTHER PTHR10381 9 201 1.2E-111 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA DC74_RS35425 475f25d52fd55eec9cef4cce1f8b6f8b 211 Pfam PF00574 Clp protease 19 198 1.2E-71 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA DC74_RS35425 475f25d52fd55eec9cef4cce1f8b6f8b 211 PANTHER PTHR10381:SF7 9 201 1.2E-111 T 23-04-2016 DC74_RS40365 3cf2abf4e71369f692878e6982fec2a6 231 PANTHER PTHR30327:SF1 1 97 2.9E-25 T 23-04-2016 DC74_RS40365 3cf2abf4e71369f692878e6982fec2a6 231 PANTHER PTHR30327 1 97 2.9E-25 T 23-04-2016 DC74_RS40365 3cf2abf4e71369f692878e6982fec2a6 231 Pfam PF02622 Uncharacterized ACR, COG1678 16 78 1.3E-17 T 23-04-2016 IPR003774 Protein of unknown function UPF0301 DC74_RS40365 3cf2abf4e71369f692878e6982fec2a6 231 SUPERFAMILY SSF143456 4 86 3.27E-23 T 23-04-2016 DC74_RS40365 3cf2abf4e71369f692878e6982fec2a6 231 Gene3D G3DSA:3.40.1740.10 2 44 6.7E-14 T 23-04-2016 DC74_RS12240 2ea3b6c0fc9408e8a8978246b577f212 158 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 15 97 2.5E-12 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS12240 2ea3b6c0fc9408e8a8978246b577f212 158 PANTHER PTHR35176 1 140 4.2E-35 T 23-04-2016 DC74_RS12240 2ea3b6c0fc9408e8a8978246b577f212 158 Gene3D G3DSA:2.30.110.10 14 144 1.5E-27 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS12240 2ea3b6c0fc9408e8a8978246b577f212 158 PANTHER PTHR35176:SF3 1 140 4.2E-35 T 23-04-2016 DC74_RS12240 2ea3b6c0fc9408e8a8978246b577f212 158 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 141 1.5E-37 T 23-04-2016 IPR019920 F420-binding domain, putative DC74_RS12240 2ea3b6c0fc9408e8a8978246b577f212 158 SUPERFAMILY SSF50475 15 140 1.04E-28 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 SUPERFAMILY SSF55103 297 553 1.26E-47 T 23-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 572 583 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 SUPERFAMILY SSF56176 34 293 1.5E-50 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 Pfam PF01565 FAD binding domain 69 205 1.2E-31 T 23-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 SUPERFAMILY SSF46548 526 651 1.69E-14 T 23-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 PANTHER PTHR11748 248 594 6.1E-268 T 23-04-2016 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 Gene3D G3DSA:1.10.1060.10 536 652 1.5E-16 T 23-04-2016 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 Gene3D G3DSA:1.10.45.10 509 535 2.5E-6 T 23-04-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 PANTHER PTHR11748:SF65 1 211 6.1E-268 T 23-04-2016 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 Pfam PF13183 4Fe-4S dicluster domain 570 640 1.7E-7 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 PANTHER PTHR11748:SF65 248 594 6.1E-268 T 23-04-2016 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 Pfam PF02754 Cysteine-rich domain 871 949 0.0058 T 23-04-2016 IPR004017 Cysteine-rich domain DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 Gene3D G3DSA:3.30.465.10 124 293 4.0E-18 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 PANTHER PTHR11748 1 211 6.1E-268 T 23-04-2016 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 Pfam PF02913 FAD linked oxidases, C-terminal domain 295 545 2.0E-54 T 23-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 DC74_RS34035 d46ae521c1b8f48cf76141100088dc5b 982 Gene3D G3DSA:3.30.43.10 17 119 5.0E-16 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 Gene3D G3DSA:3.40.50.2300 12 143 1.1E-23 T 23-04-2016 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 SMART SM00448 10 132 4.2E-12 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 SUPERFAMILY SSF52172 12 137 2.42E-22 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PANTHER PTHR22912 219 495 1.2E-162 T 23-04-2016 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PANTHER PTHR22912 515 557 1.2E-162 T 23-04-2016 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 SUPERFAMILY SSF51905 227 555 2.43E-39 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 233 544 9.9E-28 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 Gene3D G3DSA:3.50.50.60 233 337 2.8E-30 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PANTHER PTHR22912:SF138 219 495 1.2E-162 T 23-04-2016 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PANTHER PTHR22912:SF138 515 557 1.2E-162 T 23-04-2016 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 256 1.3E-32 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 267 282 1.3E-32 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 288 298 1.3E-32 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 465 486 1.3E-32 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 373 397 1.3E-32 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 427 443 1.3E-32 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 335 343 1.3E-32 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 Gene3D G3DSA:3.50.50.60 338 549 3.6E-25 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 463 479 3.6E-23 T 23-04-2016 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 377 395 3.6E-23 T 23-04-2016 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 254 3.6E-23 T 23-04-2016 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 334 352 3.6E-23 T 23-04-2016 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 508 530 3.6E-23 T 23-04-2016 DC74_RS04725 b6eef148b2f0d64a47786f99b071757a 558 Pfam PF00072 Response regulator receiver domain 12 125 2.5E-14 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.9E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.9E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.9E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 SUPERFAMILY SSF52172 2 139 7.4E-17 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 PANTHER PTHR26402 1 214 2.4E-91 T 23-04-2016 DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 PANTHER PTHR26402:SF582 1 214 2.4E-91 T 23-04-2016 DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 Gene3D G3DSA:3.40.50.2300 2 153 1.6E-25 T 23-04-2016 DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 200 1.9E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 Gene3D G3DSA:1.10.10.10 154 217 1.4E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 SMART SM00448 1 125 4.5E-10 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 SMART SM00421 153 215 2.2E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 Pfam PF00072 Response regulator receiver domain 3 113 6.4E-14 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS18960 fc1d1d0fe2af7663e7b1e7b04d4216cc 219 SUPERFAMILY SSF46894 138 201 3.74E-15 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Pfam PF00668 Condensation domain 31 324 1.8E-61 T 23-04-2016 IPR001242 Condensation domain DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 512 908 4.1E-134 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 PANTHER PTHR24095 28 1067 8.9E-269 T 23-04-2016 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 SUPERFAMILY SSF47336 1006 1136 1.57E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 SUPERFAMILY SSF56801 449 979 1.7E-149 T 23-04-2016 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Gene3D G3DSA:1.10.1200.10 1006 1130 3.9E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Pfam PF00550 Phosphopantetheine attachment site 1011 1075 2.2E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Gene3D G3DSA:2.30.38.10 795 873 3.0E-28 T 23-04-2016 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Pfam PF13745 HxxPF-repeated domain 347 437 5.8E-13 T 23-04-2016 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 SMART SM00825 Beta-ketoacyl synthase 1125 1572 1.9E-196 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 SMART SM00823 Phosphopantetheine attachment site 1009 1080 2.0E-9 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1035 1050 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Gene3D G3DSA:3.40.50.980 484 642 5.1E-48 T 23-04-2016 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Gene3D G3DSA:3.30.300.30 878 977 2.2E-27 T 23-04-2016 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Gene3D G3DSA:3.40.47.10 1397 1571 6.8E-57 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Gene3D G3DSA:3.30.559.10 62 193 4.0E-5 T 23-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 SMART SM00826 1745 1929 9.1E-15 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Pfam PF00501 AMP-binding enzyme 492 884 5.0E-99 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 SMART SM01294 1010 1076 0.0011 T 23-04-2016 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1294 1310 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 SUPERFAMILY SSF52777 33 206 3.34E-42 T 23-04-2016 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Gene3D G3DSA:3.40.50.980 643 794 6.6E-34 T 23-04-2016 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 SUPERFAMILY SSF53901 1548 1567 2.54E-91 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 SUPERFAMILY SSF53901 1121 1506 2.54E-91 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1389 1513 7.7E-40 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 SUPERFAMILY SSF52777 214 477 1.03E-56 T 23-04-2016 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Pfam PF14765 Polyketide synthase dehydratase 1746 2039 9.0E-52 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1517 1623 2.5E-14 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 PANTHER PTHR24095:SF137 28 1067 8.9E-269 T 23-04-2016 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Gene3D G3DSA:3.40.47.10 1131 1393 4.5E-97 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1124 1378 1.1E-88 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS26995 e801c75afc910e70bc67d9f2cc18496c 2295 ProSitePatterns PS00455 Putative AMP-binding domain signature. 633 644 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS36400 11f6b898bd1d5a807930e4b99f6123b4 341 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 9 340 1.2E-150 T 23-04-2016 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 DC74_RS36400 11f6b898bd1d5a807930e4b99f6123b4 341 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 341 172.438 T 23-04-2016 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 DC74_RS36400 11f6b898bd1d5a807930e4b99f6123b4 341 PANTHER PTHR10277 9 270 9.9E-120 T 23-04-2016 DC74_RS36400 11f6b898bd1d5a807930e4b99f6123b4 341 SUPERFAMILY SSF51569 9 275 1.17E-58 T 23-04-2016 DC74_RS36400 11f6b898bd1d5a807930e4b99f6123b4 341 PANTHER PTHR10277:SF3 9 270 9.9E-120 T 23-04-2016 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 DC74_RS36400 11f6b898bd1d5a807930e4b99f6123b4 341 Pfam PF00682 HMGL-like 10 268 1.4E-49 T 23-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 DC74_RS36400 11f6b898bd1d5a807930e4b99f6123b4 341 Pfam PF07836 DmpG-like communication domain 277 338 2.5E-27 T 23-04-2016 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 DC74_RS36400 11f6b898bd1d5a807930e4b99f6123b4 341 Gene3D G3DSA:3.20.20.70 9 268 9.2E-48 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS36400 11f6b898bd1d5a807930e4b99f6123b4 341 Gene3D G3DSA:1.10.8.60 280 341 2.2E-26 T 23-04-2016 DC74_RS36400 11f6b898bd1d5a807930e4b99f6123b4 341 SUPERFAMILY SSF89000 292 340 1.65E-15 T 23-04-2016 DC74_RS36400 11f6b898bd1d5a807930e4b99f6123b4 341 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 279 337 3.0E-20 T 23-04-2016 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 Gene3D G3DSA:3.30.450.20 34 171 1.0E-42 T 23-04-2016 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 SUPERFAMILY SSF55785 218 302 3.43E-7 T 23-04-2016 IPR000014 PAS domain DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 414 527 7.5E-21 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 Gene3D G3DSA:3.30.450.20 215 308 4.3E-8 T 23-04-2016 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 SUPERFAMILY SSF103190 39 171 4.71E-29 T 23-04-2016 IPR029151 Periplasmic sensor domain-like DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 Pfam PF17203 Single cache domain 3 40 169 1.6E-22 T 23-04-2016 IPR033463 Single cache domain 3 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 SUPERFAMILY SSF55890 318 367 9.81E-10 T 23-04-2016 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 SUPERFAMILY SSF55874 381 525 3.54E-31 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 PANTHER PTHR24423 1 160 1.7E-112 T 23-04-2016 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 PANTHER PTHR24423 193 548 1.7E-112 T 23-04-2016 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 Gene3D G3DSA:3.30.565.10 389 526 3.9E-32 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 Pfam PF00989 PAS fold 216 253 2.9E-5 T 23-04-2016 IPR013767 PAS fold GO:0006355 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 Gene3D G3DSA:1.10.287.130 309 367 1.6E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 SMART SM00387 413 528 5.6E-32 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 318 365 1.2E-10 T 23-04-2016 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 PANTHER PTHR24423:SF523 1 160 1.7E-112 T 23-04-2016 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 PANTHER PTHR24423:SF523 193 548 1.7E-112 T 23-04-2016 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 506 3.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 468 3.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS06565 7f7c8f7611a1ee22cb7908fc1f6dc860 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 525 3.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS11820 759c8d7b896910b9567b7ef0471e3c0a 258 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 4 256 39.528 T 23-04-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 DC74_RS11820 759c8d7b896910b9567b7ef0471e3c0a 258 Pfam PF00121 Triosephosphate isomerase 7 253 6.9E-89 T 23-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 DC74_RS11820 759c8d7b896910b9567b7ef0471e3c0a 258 Gene3D G3DSA:3.20.20.70 4 255 8.2E-107 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS11820 759c8d7b896910b9567b7ef0471e3c0a 258 SUPERFAMILY SSF51351 4 255 5.11E-92 T 23-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 DC74_RS11820 759c8d7b896910b9567b7ef0471e3c0a 258 ProSitePatterns PS00171 Triosephosphate isomerase active site. 171 181 - T 23-04-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 DC74_RS11820 759c8d7b896910b9567b7ef0471e3c0a 258 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 247 3.3E-55 T 23-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 DC74_RS11820 759c8d7b896910b9567b7ef0471e3c0a 258 PANTHER PTHR21139 4 256 5.4E-114 T 23-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 DC74_RS09565 709c3b412c66526bcec7caa69e7d8dd8 420 SUPERFAMILY SSF52954 325 419 2.13E-20 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS09565 709c3b412c66526bcec7caa69e7d8dd8 420 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 417 30.569 T 23-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 DC74_RS09565 709c3b412c66526bcec7caa69e7d8dd8 420 Gene3D G3DSA:3.40.50.800 326 417 3.7E-26 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS09565 709c3b412c66526bcec7caa69e7d8dd8 420 Pfam PF13393 Histidyl-tRNA synthetase 9 309 1.5E-39 T 23-04-2016 DC74_RS09565 709c3b412c66526bcec7caa69e7d8dd8 420 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 407 2.8E-130 T 23-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 DC74_RS09565 709c3b412c66526bcec7caa69e7d8dd8 420 Gene3D G3DSA:3.30.930.10 219 319 1.7E-79 T 23-04-2016 DC74_RS09565 709c3b412c66526bcec7caa69e7d8dd8 420 Gene3D G3DSA:3.30.930.10 3 185 1.7E-79 T 23-04-2016 DC74_RS09565 709c3b412c66526bcec7caa69e7d8dd8 420 PANTHER PTHR11476:SF9 3 420 1.8E-185 T 23-04-2016 DC74_RS09565 709c3b412c66526bcec7caa69e7d8dd8 420 SUPERFAMILY SSF55681 4 315 1.31E-80 T 23-04-2016 DC74_RS09565 709c3b412c66526bcec7caa69e7d8dd8 420 Pfam PF03129 Anticodon binding domain 329 416 8.4E-10 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS09565 709c3b412c66526bcec7caa69e7d8dd8 420 PIRSF PIRSF001549 1 419 1.7E-100 T 23-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 DC74_RS09565 709c3b412c66526bcec7caa69e7d8dd8 420 PANTHER PTHR11476 3 420 1.8E-185 T 23-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 DC74_RS39125 ef39429ff94e22c6bd2bba90501861d5 280 Gene3D G3DSA:3.40.50.720 2 211 3.8E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39125 ef39429ff94e22c6bd2bba90501861d5 280 Pfam PF13460 NAD(P)H-binding 6 179 8.0E-23 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39125 ef39429ff94e22c6bd2bba90501861d5 280 PANTHER PTHR14194 1 279 6.9E-65 T 23-04-2016 DC74_RS39125 ef39429ff94e22c6bd2bba90501861d5 280 PANTHER PTHR14194:SF21 1 279 6.9E-65 T 23-04-2016 DC74_RS39125 ef39429ff94e22c6bd2bba90501861d5 280 SUPERFAMILY SSF51735 2 243 1.34E-50 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15175 a82940f00406549dd7faa81a6f16539f 363 Gene3D G3DSA:3.30.2010.10 70 156 2.7E-21 T 23-04-2016 DC74_RS15175 a82940f00406549dd7faa81a6f16539f 363 Pfam PF01435 Peptidase family M48 75 270 8.4E-25 T 23-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DC74_RS15175 a82940f00406549dd7faa81a6f16539f 363 PANTHER PTHR22726 11 295 3.4E-41 T 23-04-2016 DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 1.5E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 Gene3D G3DSA:1.10.10.60 4 64 3.4E-23 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 SUPERFAMILY SSF46689 5 66 6.31E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 53 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 82 219 2.1E-26 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 PRINTS PR00400 Tetracycline repressor protein signature 22 45 7.1E-10 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 PRINTS PR00400 Tetracycline repressor protein signature 139 158 7.1E-10 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 PANTHER PTHR30055:SF36 4 103 6.1E-23 T 23-04-2016 DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 Gene3D G3DSA:1.10.357.10 81 220 6.7E-32 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 PANTHER PTHR30055 4 103 6.1E-23 T 23-04-2016 DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.2E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.2E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS24875 3c825ab37d823d84ca3e9ded2f5314f9 226 SUPERFAMILY SSF48498 81 219 3.34E-24 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS14985 fb7d6f8b92b81bc5f5daeb71d44b0300 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 147 4.7E-26 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS14985 fb7d6f8b92b81bc5f5daeb71d44b0300 361 Pfam PF00107 Zinc-binding dehydrogenase 190 319 5.7E-30 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS14985 fb7d6f8b92b81bc5f5daeb71d44b0300 361 Gene3D G3DSA:3.90.180.10 3 182 1.3E-53 T 23-04-2016 IPR011032 GroES-like DC74_RS14985 fb7d6f8b92b81bc5f5daeb71d44b0300 361 PANTHER PTHR11695:SF417 17 361 1.5E-245 T 23-04-2016 DC74_RS14985 fb7d6f8b92b81bc5f5daeb71d44b0300 361 SMART SM00829 12 361 1.0E-4 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS14985 fb7d6f8b92b81bc5f5daeb71d44b0300 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 361 1.8E-208 T 23-04-2016 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 DC74_RS14985 fb7d6f8b92b81bc5f5daeb71d44b0300 361 PANTHER PTHR11695 17 361 1.5E-245 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS14985 fb7d6f8b92b81bc5f5daeb71d44b0300 361 Gene3D G3DSA:3.40.50.720 183 302 1.7E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS14985 fb7d6f8b92b81bc5f5daeb71d44b0300 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS14985 fb7d6f8b92b81bc5f5daeb71d44b0300 361 SUPERFAMILY SSF51735 154 326 1.42E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS14985 fb7d6f8b92b81bc5f5daeb71d44b0300 361 SUPERFAMILY SSF50129 4 186 4.41E-54 T 23-04-2016 IPR011032 GroES-like DC74_RS14985 fb7d6f8b92b81bc5f5daeb71d44b0300 361 SUPERFAMILY SSF50129 310 360 1.65E-6 T 23-04-2016 IPR011032 GroES-like DC74_RS27750 45a2ec24b95732fd4c8b3da92ea0674e 483 PANTHER PTHR31806:SF2 1 468 6.5E-165 T 23-04-2016 DC74_RS27750 45a2ec24b95732fd4c8b3da92ea0674e 483 PANTHER PTHR31806 1 468 6.5E-165 T 23-04-2016 DC74_RS27750 45a2ec24b95732fd4c8b3da92ea0674e 483 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 10 439 4.6E-76 T 23-04-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 DC74_RS27750 45a2ec24b95732fd4c8b3da92ea0674e 483 PIRSF PIRSF002744 1 468 6.3E-68 T 23-04-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 PANTHER PTHR10992:SF878 45 140 2.3E-58 T 23-04-2016 DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 PANTHER PTHR10992:SF878 184 303 2.3E-58 T 23-04-2016 DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 Pfam PF00561 alpha/beta hydrolase fold 91 513 5.6E-23 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 Gene3D G3DSA:3.40.50.1820 363 531 5.4E-49 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 Gene3D G3DSA:3.40.50.1820 56 141 5.4E-49 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 Gene3D G3DSA:3.40.50.1820 185 311 5.4E-49 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 SUPERFAMILY SSF53474 187 241 9.14E-23 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 SUPERFAMILY SSF53474 373 531 9.14E-23 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 SUPERFAMILY SSF53474 86 142 9.14E-23 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 PANTHER PTHR10992 472 533 2.3E-58 T 23-04-2016 DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 PANTHER PTHR10992 45 140 2.3E-58 T 23-04-2016 DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 PANTHER PTHR10992:SF878 472 533 2.3E-58 T 23-04-2016 DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 SUPERFAMILY SSF53474 160 329 6.61E-6 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS29825 703e92039c00add4d600e3787fc2c6cd 569 PANTHER PTHR10992 184 303 2.3E-58 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2539 2554 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 ProSitePatterns PS00012 Phosphopantetheine attachment site. 988 1003 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2023 2430 1.8E-137 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 487 881 1.3E-132 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 SUPERFAMILY SSF52777 1727 1989 6.23E-52 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 SUPERFAMILY SSF52777 191 430 1.45E-44 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Gene3D G3DSA:3.40.50.980 2161 2317 4.8E-48 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Pfam PF00550 Phosphopantetheine attachment site 2517 2580 1.0E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Pfam PF00550 Phosphopantetheine attachment site 966 1028 4.0E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Pfam PF00501 AMP-binding enzyme 467 856 8.5E-91 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Pfam PF00501 AMP-binding enzyme 2003 2406 3.6E-103 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2152 2163 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 ProSitePatterns PS00455 Putative AMP-binding domain signature. 606 617 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Gene3D G3DSA:2.30.38.10 2318 2396 1.2E-25 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Gene3D G3DSA:2.30.38.10 770 847 2.9E-27 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Gene3D G3DSA:3.30.300.30 2401 2519 5.6E-39 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Gene3D G3DSA:3.30.300.30 852 968 5.1E-39 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1376 1533 1.3E-30 T 23-04-2016 IPR010060 Non-ribosomal peptide synthase DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 SUPERFAMILY SSF47336 958 1029 2.22E-18 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 SUPERFAMILY SSF56801 451 977 2.62E-150 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Pfam PF13193 AMP-binding enzyme C-terminal domain 865 940 9.2E-16 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Pfam PF13193 AMP-binding enzyme C-terminal domain 2414 2489 8.6E-11 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 PANTHER PTHR24095 1488 1501 0.0 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 PANTHER PTHR24095 1518 2489 0.0 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 PANTHER PTHR24095 1 1019 0.0 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Pfam PF00668 Condensation domain 1068 1361 9.5E-34 T 23-04-2016 IPR001242 Condensation domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Pfam PF00668 Condensation domain 9 302 1.7E-53 T 23-04-2016 IPR001242 Condensation domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Pfam PF00668 Condensation domain 1541 1841 3.1E-61 T 23-04-2016 IPR001242 Condensation domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 SUPERFAMILY SSF52777 11 185 5.78E-35 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 SUPERFAMILY SSF56801 1962 2527 1.44E-165 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 SUPERFAMILY SSF52777 1238 1509 1.67E-25 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Gene3D G3DSA:1.10.1200.10 969 1034 7.3E-26 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Gene3D G3DSA:1.10.1200.10 2520 2582 2.0E-25 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 SMART SM00823 Phosphopantetheine attachment site 2515 2584 1.6E-5 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 SMART SM00823 Phosphopantetheine attachment site 964 1032 1.3E-8 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 SUPERFAMILY SSF52777 1540 1742 1.56E-43 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 SUPERFAMILY SSF47336 2509 2580 2.22E-19 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Gene3D G3DSA:3.40.50.980 629 769 2.9E-39 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 PANTHER PTHR24095:SF137 1488 1501 0.0 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 PANTHER PTHR24095:SF137 1518 2489 0.0 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 PANTHER PTHR24095:SF137 1 1019 0.0 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 SUPERFAMILY SSF52777 1046 1251 3.11E-31 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Gene3D G3DSA:3.40.50.980 459 628 5.1E-41 T 23-04-2016 DC74_RS04640 c57945737332ee3efa29bedaece47f92 2615 Gene3D G3DSA:3.40.50.980 1995 2160 5.6E-50 T 23-04-2016 DC74_RS10725 9217ea6544520436e976c1087cf0bc36 217 Gene3D G3DSA:1.10.357.10 16 194 3.9E-27 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS10725 9217ea6544520436e976c1087cf0bc36 217 PANTHER PTHR30055 2 215 2.0E-49 T 23-04-2016 DC74_RS10725 9217ea6544520436e976c1087cf0bc36 217 PANTHER PTHR30055:SF74 2 215 2.0E-49 T 23-04-2016 DC74_RS10725 9217ea6544520436e976c1087cf0bc36 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 5.2E-14 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10725 9217ea6544520436e976c1087cf0bc36 217 SUPERFAMILY SSF46689 6 79 3.09E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS10725 9217ea6544520436e976c1087cf0bc36 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.5E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10725 9217ea6544520436e976c1087cf0bc36 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.5E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13205 a20bce6d9bc34d78ae0ec6da2571fb8e 301 PANTHER PTHR39456 8 300 3.1E-179 T 23-04-2016 DC74_RS13205 a20bce6d9bc34d78ae0ec6da2571fb8e 301 PIRSF PIRSF007580 4 297 2.1E-123 T 23-04-2016 IPR016516 Uncharacterised conserved protein UCP07580 DC74_RS13205 a20bce6d9bc34d78ae0ec6da2571fb8e 301 PANTHER PTHR39456:SF1 8 300 3.1E-179 T 23-04-2016 DC74_RS13205 a20bce6d9bc34d78ae0ec6da2571fb8e 301 Pfam PF10118 Predicted metal-dependent hydrolase 20 277 1.6E-80 T 23-04-2016 IPR016516 Uncharacterised conserved protein UCP07580 DC74_RS20425 810b095615de80c4935492bac54a557b 399 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 44 369 2.1E-127 T 23-04-2016 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 DC74_RS20425 810b095615de80c4935492bac54a557b 399 SUPERFAMILY SSF52518 46 374 1.66E-90 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS20425 810b095615de80c4935492bac54a557b 399 PANTHER PTHR11516:SF1 49 386 6.2E-112 T 23-04-2016 DC74_RS20425 810b095615de80c4935492bac54a557b 399 Gene3D G3DSA:3.40.50.970 38 369 6.7E-115 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS20425 810b095615de80c4935492bac54a557b 399 PANTHER PTHR11516 49 386 6.2E-112 T 23-04-2016 DC74_RS20425 810b095615de80c4935492bac54a557b 399 Pfam PF00676 Dehydrogenase E1 component 72 321 7.2E-71 T 23-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 DC74_RS12010 4ca7c3a5e2d984bb37625f461df9b4e2 980 SUPERFAMILY SSF52540 731 977 2.06E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12010 4ca7c3a5e2d984bb37625f461df9b4e2 980 Pfam PF00176 SNF2 family N-terminal domain 536 792 3.8E-49 T 23-04-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 DC74_RS12010 4ca7c3a5e2d984bb37625f461df9b4e2 980 Gene3D G3DSA:3.40.50.300 518 679 7.9E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12010 4ca7c3a5e2d984bb37625f461df9b4e2 980 Pfam PF12419 SNF2 Helicase protein 348 462 3.3E-32 T 23-04-2016 IPR022138 Helicase SWF/SNF-related DC74_RS12010 4ca7c3a5e2d984bb37625f461df9b4e2 980 SMART SM00487 516 693 1.0E-25 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS12010 4ca7c3a5e2d984bb37625f461df9b4e2 980 Pfam PF00271 Helicase conserved C-terminal domain 809 920 5.4E-18 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS12010 4ca7c3a5e2d984bb37625f461df9b4e2 980 SUPERFAMILY SSF52540 509 724 7.6E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12010 4ca7c3a5e2d984bb37625f461df9b4e2 980 PANTHER PTHR10799 513 973 5.0E-161 T 23-04-2016 DC74_RS12010 4ca7c3a5e2d984bb37625f461df9b4e2 980 Gene3D G3DSA:3.40.50.300 806 956 5.2E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12010 4ca7c3a5e2d984bb37625f461df9b4e2 980 SMART SM00490 838 920 1.2E-24 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS15470 822da0255bf01ae1de4d0e96aa93ccd3 988 Gene3D G3DSA:2.60.120.260 848 986 1.5E-25 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS15470 822da0255bf01ae1de4d0e96aa93ccd3 988 SUPERFAMILY SSF49785 853 983 5.53E-20 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS15470 822da0255bf01ae1de4d0e96aa93ccd3 988 SUPERFAMILY SSF55545 47 196 1.22E-13 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like DC74_RS15470 822da0255bf01ae1de4d0e96aa93ccd3 988 Pfam PF00754 F5/8 type C domain 866 978 3.5E-21 T 23-04-2016 IPR000421 Coagulation factor 5/8 C-terminal domain DC74_RS15470 822da0255bf01ae1de4d0e96aa93ccd3 988 Pfam PF07555 beta-N-acetylglucosaminidase 201 509 3.3E-99 T 23-04-2016 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 DC74_RS15470 822da0255bf01ae1de4d0e96aa93ccd3 988 PANTHER PTHR13170 139 493 4.8E-66 T 23-04-2016 DC74_RS15470 822da0255bf01ae1de4d0e96aa93ccd3 988 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 47 195 1.7E-19 T 23-04-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS15470 822da0255bf01ae1de4d0e96aa93ccd3 988 SUPERFAMILY SSF51445 200 504 5.69E-85 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS15470 822da0255bf01ae1de4d0e96aa93ccd3 988 PANTHER PTHR13170:SF20 139 493 4.8E-66 T 23-04-2016 DC74_RS15470 822da0255bf01ae1de4d0e96aa93ccd3 988 Gene3D G3DSA:3.30.379.10 37 195 2.8E-18 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like DC74_RS15470 822da0255bf01ae1de4d0e96aa93ccd3 988 SUPERFAMILY SSF140657 519 648 2.09E-14 T 23-04-2016 DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 Pfam PF00570 HRDC domain 552 618 1.2E-22 T 23-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 Pfam PF00270 DEAD/DEAH box helicase 38 196 1.8E-16 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 Pfam PF09382 RQC domain 416 530 3.9E-35 T 23-04-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 Gene3D G3DSA:1.10.10.10 355 530 1.4E-54 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 Gene3D G3DSA:3.40.50.300 21 208 1.6E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 Pfam PF00271 Helicase conserved C-terminal domain 235 341 5.7E-14 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 Pfam PF16124 RecQ zinc-binding 353 414 1.5E-15 T 23-04-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 PANTHER PTHR13710 21 619 1.5E-278 T 23-04-2016 DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 SMART SM00487 31 225 5.4E-26 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 24 618 1.7E-230 T 23-04-2016 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 SMART SM00490 260 341 2.9E-23 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 25 477 7.7E-149 T 23-04-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 SMART SM00341 548 628 1.1E-15 T 23-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 SUPERFAMILY SSF47819 545 620 6.98E-22 T 23-04-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 SUPERFAMILY SSF52540 217 469 1.12E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 Gene3D G3DSA:1.10.150.80 554 618 1.8E-16 T 23-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 SMART SM00956 421 527 1.9E-45 T 23-04-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 Gene3D G3DSA:3.40.50.300 216 354 1.6E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 PANTHER PTHR13710:SF81 21 619 1.5E-278 T 23-04-2016 DC74_RS18065 a7ebb085f8bc75f48035fdeec9cc5ed2 685 SUPERFAMILY SSF52540 21 206 1.74E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36510 77fcb3ac11978484c3cfbcdaa1a0c2a7 701 Gene3D G3DSA:3.30.450.40 303 455 2.0E-20 T 23-04-2016 IPR029016 GAF domain-like DC74_RS36510 77fcb3ac11978484c3cfbcdaa1a0c2a7 701 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 506 690 2.4E-47 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS36510 77fcb3ac11978484c3cfbcdaa1a0c2a7 701 SUPERFAMILY SSF81606 493 689 6.28E-6 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS36510 77fcb3ac11978484c3cfbcdaa1a0c2a7 701 Gene3D G3DSA:3.30.450.20 179 271 7.4E-10 T 23-04-2016 DC74_RS36510 77fcb3ac11978484c3cfbcdaa1a0c2a7 701 SUPERFAMILY SSF55785 179 267 3.81E-9 T 23-04-2016 IPR000014 PAS domain DC74_RS36510 77fcb3ac11978484c3cfbcdaa1a0c2a7 701 Pfam PF13185 GAF domain 312 449 4.4E-15 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS36510 77fcb3ac11978484c3cfbcdaa1a0c2a7 701 Pfam PF08448 PAS fold 179 262 1.2E-6 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS36510 77fcb3ac11978484c3cfbcdaa1a0c2a7 701 SUPERFAMILY SSF55781 313 461 2.03E-20 T 23-04-2016 IPR029016 GAF domain-like DC74_RS36510 77fcb3ac11978484c3cfbcdaa1a0c2a7 701 PANTHER PTHR21021 408 701 2.1E-63 T 23-04-2016 DC74_RS36510 77fcb3ac11978484c3cfbcdaa1a0c2a7 701 SMART SM00065 311 458 1.6E-9 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS36510 77fcb3ac11978484c3cfbcdaa1a0c2a7 701 PANTHER PTHR21021:SF19 408 701 2.1E-63 T 23-04-2016 DC74_RS36510 77fcb3ac11978484c3cfbcdaa1a0c2a7 701 SMART SM00331 476 692 1.3E-34 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS37725 1e3631ad54255d1995ee9648461488f8 320 SUPERFAMILY SSF51412 2 314 2.9E-46 T 23-04-2016 DC74_RS37725 1e3631ad54255d1995ee9648461488f8 320 PANTHER PTHR32332:SF17 2 316 3.1E-81 T 23-04-2016 DC74_RS37725 1e3631ad54255d1995ee9648461488f8 320 Gene3D G3DSA:3.20.20.70 2 268 5.0E-47 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS37725 1e3631ad54255d1995ee9648461488f8 320 Pfam PF03060 Nitronate monooxygenase 81 308 8.9E-33 T 23-04-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 DC74_RS37725 1e3631ad54255d1995ee9648461488f8 320 PANTHER PTHR32332 2 316 3.1E-81 T 23-04-2016 DC74_RS01625 d18c85d8390e70725eba39e7f71f5f51 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 5.3E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01625 d18c85d8390e70725eba39e7f71f5f51 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 5.3E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01625 d18c85d8390e70725eba39e7f71f5f51 188 PANTHER PTHR30055:SF75 1 177 7.2E-33 T 23-04-2016 DC74_RS01625 d18c85d8390e70725eba39e7f71f5f51 188 Gene3D G3DSA:1.10.10.60 9 54 1.5E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01625 d18c85d8390e70725eba39e7f71f5f51 188 Gene3D G3DSA:1.10.357.10 55 182 3.9E-15 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS01625 d18c85d8390e70725eba39e7f71f5f51 188 PANTHER PTHR30055 1 177 7.2E-33 T 23-04-2016 DC74_RS01625 d18c85d8390e70725eba39e7f71f5f51 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS01625 d18c85d8390e70725eba39e7f71f5f51 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 57 9.6E-16 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01625 d18c85d8390e70725eba39e7f71f5f51 188 SUPERFAMILY SSF46689 6 74 1.23E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS16745 e0d49997ab94be24f6e10b05ab2a9756 1189 Gene3D G3DSA:3.90.550.10 3 239 3.0E-25 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS16745 e0d49997ab94be24f6e10b05ab2a9756 1189 SUPERFAMILY SSF53756 905 1188 1.57E-12 T 23-04-2016 DC74_RS16745 e0d49997ab94be24f6e10b05ab2a9756 1189 PANTHER PTHR22916 1 475 3.8E-41 T 23-04-2016 DC74_RS16745 e0d49997ab94be24f6e10b05ab2a9756 1189 Pfam PF00535 Glycosyl transferase family 2 8 131 7.3E-14 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS16745 e0d49997ab94be24f6e10b05ab2a9756 1189 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 825 1188 8.3E-85 T 23-04-2016 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 DC74_RS16745 e0d49997ab94be24f6e10b05ab2a9756 1189 SUPERFAMILY SSF53448 1 225 2.65E-26 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS16745 e0d49997ab94be24f6e10b05ab2a9756 1189 PANTHER PTHR22916:SF23 1 475 3.8E-41 T 23-04-2016 DC74_RS17125 fccb5d3f8986c187401606d5e23ea1b3 390 SUPERFAMILY SSF56645 12 247 2.23E-78 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS17125 fccb5d3f8986c187401606d5e23ea1b3 390 PANTHER PTHR10909 13 389 1.4E-171 T 23-04-2016 DC74_RS17125 fccb5d3f8986c187401606d5e23ea1b3 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 124 3.6E-29 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS17125 fccb5d3f8986c187401606d5e23ea1b3 390 Gene3D G3DSA:1.20.140.10 224 389 1.1E-67 T 23-04-2016 DC74_RS17125 fccb5d3f8986c187401606d5e23ea1b3 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 389 6.5E-49 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS17125 fccb5d3f8986c187401606d5e23ea1b3 390 Gene3D G3DSA:1.10.540.10 13 124 7.1E-33 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS17125 fccb5d3f8986c187401606d5e23ea1b3 390 PANTHER PTHR10909:SF10 13 389 1.4E-171 T 23-04-2016 DC74_RS17125 fccb5d3f8986c187401606d5e23ea1b3 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 348 367 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS17125 fccb5d3f8986c187401606d5e23ea1b3 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 223 4.2E-27 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS17125 fccb5d3f8986c187401606d5e23ea1b3 390 Gene3D G3DSA:2.40.110.10 128 223 2.0E-40 T 23-04-2016 DC74_RS17125 fccb5d3f8986c187401606d5e23ea1b3 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS17125 fccb5d3f8986c187401606d5e23ea1b3 390 SUPERFAMILY SSF47203 234 389 3.14E-57 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS06125 19410aad0e829b87442511df30c3bd05 358 PANTHER PTHR30472:SF24 27 357 1.9E-83 T 23-04-2016 DC74_RS06125 19410aad0e829b87442511df30c3bd05 358 SUPERFAMILY SSF81345 29 351 2.09E-56 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS06125 19410aad0e829b87442511df30c3bd05 358 Gene3D G3DSA:1.10.3470.10 35 355 2.1E-68 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS06125 19410aad0e829b87442511df30c3bd05 358 PANTHER PTHR30472 27 357 1.9E-83 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS06125 19410aad0e829b87442511df30c3bd05 358 Pfam PF01032 FecCD transport family 47 351 1.3E-63 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS06170 47f33a491b87c750ea91411a14267b26 398 PIRSF PIRSF036794 20 398 5.1E-76 T 23-04-2016 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type DC74_RS06170 47f33a491b87c750ea91411a14267b26 398 Pfam PF05139 Erythromycin esterase 52 394 8.5E-65 T 23-04-2016 IPR007815 Erythromycin esterase GO:0046677 DC74_RS06170 47f33a491b87c750ea91411a14267b26 398 PANTHER PTHR31299 24 326 1.8E-50 T 23-04-2016 DC74_RS06170 47f33a491b87c750ea91411a14267b26 398 PANTHER PTHR31299:SF0 24 326 1.8E-50 T 23-04-2016 DC74_RS06170 47f33a491b87c750ea91411a14267b26 398 Gene3D G3DSA:3.40.1660.10 279 326 9.9E-13 T 23-04-2016 DC74_RS06170 47f33a491b87c750ea91411a14267b26 398 Gene3D G3DSA:3.40.1660.10 24 53 9.9E-13 T 23-04-2016 DC74_RS06170 47f33a491b87c750ea91411a14267b26 398 Gene3D G3DSA:3.30.1870.10 54 127 4.2E-17 T 23-04-2016 DC74_RS06170 47f33a491b87c750ea91411a14267b26 398 SUPERFAMILY SSF159501 4 397 1.54E-81 T 23-04-2016 DC74_RS20935 9c4e1fcadc225a92a164c0a9d9d5f585 298 PANTHER PTHR30126 1 298 6.2E-71 T 23-04-2016 DC74_RS20935 9c4e1fcadc225a92a164c0a9d9d5f585 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.0E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS20935 9c4e1fcadc225a92a164c0a9d9d5f585 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.0E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS20935 9c4e1fcadc225a92a164c0a9d9d5f585 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.0E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS20935 9c4e1fcadc225a92a164c0a9d9d5f585 298 SUPERFAMILY SSF53850 81 296 7.6E-23 T 23-04-2016 DC74_RS20935 9c4e1fcadc225a92a164c0a9d9d5f585 298 SUPERFAMILY SSF46785 1 79 7.63E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20935 9c4e1fcadc225a92a164c0a9d9d5f585 298 Gene3D G3DSA:3.40.190.10 90 168 3.7E-5 T 23-04-2016 DC74_RS20935 9c4e1fcadc225a92a164c0a9d9d5f585 298 Pfam PF03466 LysR substrate binding domain 86 295 3.4E-22 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS20935 9c4e1fcadc225a92a164c0a9d9d5f585 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.9E-20 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS20935 9c4e1fcadc225a92a164c0a9d9d5f585 298 Gene3D G3DSA:3.40.190.10 169 261 4.8E-13 T 23-04-2016 DC74_RS20935 9c4e1fcadc225a92a164c0a9d9d5f585 298 Gene3D G3DSA:1.10.10.10 1 80 4.8E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20935 9c4e1fcadc225a92a164c0a9d9d5f585 298 PANTHER PTHR30126:SF31 1 298 6.2E-71 T 23-04-2016 DC74_RS02930 7da06d60d3e4f44f8cc58bf047ac2a74 179 Pfam PF00583 Acetyltransferase (GNAT) family 69 139 3.1E-12 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS02930 7da06d60d3e4f44f8cc58bf047ac2a74 179 Gene3D G3DSA:3.40.630.30 11 171 2.4E-27 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS02930 7da06d60d3e4f44f8cc58bf047ac2a74 179 SUPERFAMILY SSF55729 10 151 3.72E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS02930 7da06d60d3e4f44f8cc58bf047ac2a74 179 PANTHER PTHR23091 4 139 6.5E-18 T 23-04-2016 DC74_RS30505 038a6a18840da3609768ecbc5dd5e9bd 453 PANTHER PTHR22574:SF14 75 449 3.9E-79 T 23-04-2016 DC74_RS30505 038a6a18840da3609768ecbc5dd5e9bd 453 PANTHER PTHR22574 75 449 3.9E-79 T 23-04-2016 DC74_RS12995 a636203c98da62f25860eea16aca46bd 452 Pfam PF07730 Histidine kinase 234 300 2.1E-18 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS12995 a636203c98da62f25860eea16aca46bd 452 Gene3D G3DSA:3.30.565.10 350 443 3.6E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS12995 a636203c98da62f25860eea16aca46bd 452 SUPERFAMILY SSF55874 327 443 1.26E-17 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS12995 a636203c98da62f25860eea16aca46bd 452 PANTHER PTHR24421 94 443 9.6E-105 T 23-04-2016 DC74_RS12995 a636203c98da62f25860eea16aca46bd 452 PANTHER PTHR24421:SF26 94 443 9.6E-105 T 23-04-2016 DC74_RS12995 a636203c98da62f25860eea16aca46bd 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 443 4.9E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28900 236d81d07df4abdfe6a8af68db7bed86 464 SUPERFAMILY SSF53383 27 441 3.25E-111 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS28900 236d81d07df4abdfe6a8af68db7bed86 464 Pfam PF00202 Aminotransferase class-III 36 441 1.2E-86 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS28900 236d81d07df4abdfe6a8af68db7bed86 464 Gene3D G3DSA:3.90.1150.10 316 443 3.9E-53 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS28900 236d81d07df4abdfe6a8af68db7bed86 464 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS28900 236d81d07df4abdfe6a8af68db7bed86 464 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 19 446 5.1E-153 T 23-04-2016 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|UniPathway: UPA00067 DC74_RS28900 236d81d07df4abdfe6a8af68db7bed86 464 PANTHER PTHR11986 12 449 9.8E-164 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS28900 236d81d07df4abdfe6a8af68db7bed86 464 Gene3D G3DSA:3.40.640.10 74 315 1.3E-59 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS28900 236d81d07df4abdfe6a8af68db7bed86 464 PANTHER PTHR11986:SF7 12 449 9.8E-164 T 23-04-2016 DC74_RS39185 4cf2d49fb6636ce71275a1c8bbd497a4 871 PANTHER PTHR36932 512 766 5.3E-27 T 23-04-2016 DC74_RS39185 4cf2d49fb6636ce71275a1c8bbd497a4 871 PANTHER PTHR36932:SF1 512 766 5.3E-27 T 23-04-2016 DC74_RS39185 4cf2d49fb6636ce71275a1c8bbd497a4 871 Pfam PF05893 Acyl-CoA reductase (LuxC) 82 464 2.5E-79 T 23-04-2016 IPR008670 Acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723|UniPathway: UPA00569 DC74_RS39185 4cf2d49fb6636ce71275a1c8bbd497a4 871 Gene3D G3DSA:3.40.605.10 116 284 1.7E-8 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS39185 4cf2d49fb6636ce71275a1c8bbd497a4 871 Gene3D G3DSA:3.40.50.980 564 679 7.9E-10 T 23-04-2016 DC74_RS39185 4cf2d49fb6636ce71275a1c8bbd497a4 871 Pfam PF00501 AMP-binding enzyme 509 720 9.3E-9 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS39185 4cf2d49fb6636ce71275a1c8bbd497a4 871 SUPERFAMILY SSF56801 423 827 6.28E-28 T 23-04-2016 DC74_RS39185 4cf2d49fb6636ce71275a1c8bbd497a4 871 SUPERFAMILY SSF53720 77 338 7.29E-14 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS10125 15742c63bd9f1f3be4a695db90b052ba 390 Gene3D G3DSA:3.40.50.200 26 327 6.5E-79 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS10125 15742c63bd9f1f3be4a695db90b052ba 390 PANTHER PTHR10795:SF419 5 334 7.7E-61 T 23-04-2016 DC74_RS10125 15742c63bd9f1f3be4a695db90b052ba 390 PANTHER PTHR10795 5 334 7.7E-61 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS10125 15742c63bd9f1f3be4a695db90b052ba 390 PRINTS PR00723 Subtilisin serine protease family (S8) signature 264 280 1.8E-14 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS10125 15742c63bd9f1f3be4a695db90b052ba 390 PRINTS PR00723 Subtilisin serine protease family (S8) signature 52 71 1.8E-14 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS10125 15742c63bd9f1f3be4a695db90b052ba 390 PRINTS PR00723 Subtilisin serine protease family (S8) signature 92 105 1.8E-14 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS10125 15742c63bd9f1f3be4a695db90b052ba 390 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 57 68 - T 23-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site DC74_RS10125 15742c63bd9f1f3be4a695db90b052ba 390 Pfam PF00082 Subtilase family 52 315 5.3E-44 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS10125 15742c63bd9f1f3be4a695db90b052ba 390 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 42 381 2.2E-93 T 23-04-2016 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 DC74_RS10125 15742c63bd9f1f3be4a695db90b052ba 390 SUPERFAMILY SSF52743 34 329 3.53E-79 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS16700 0a9a8f0b020f8e64af20024f0e41c343 368 PANTHER PTHR11075 25 367 5.2E-144 T 23-04-2016 DC74_RS16700 0a9a8f0b020f8e64af20024f0e41c343 368 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 363 9.1E-155 T 23-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 DC74_RS16700 0a9a8f0b020f8e64af20024f0e41c343 368 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 23-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 DC74_RS16700 0a9a8f0b020f8e64af20024f0e41c343 368 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 364 38.312 T 23-04-2016 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 DC74_RS16700 0a9a8f0b020f8e64af20024f0e41c343 368 PANTHER PTHR11075:SF6 25 367 5.2E-144 T 23-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 DC74_RS16700 0a9a8f0b020f8e64af20024f0e41c343 368 SMART SM00937 84 194 9.6E-43 T 23-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 DC74_RS16700 0a9a8f0b020f8e64af20024f0e41c343 368 Pfam PF03462 PCRF domain 30 219 1.9E-54 T 23-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 DC74_RS16700 0a9a8f0b020f8e64af20024f0e41c343 368 Gene3D G3DSA:1.20.58.410 4 115 1.7E-32 T 23-04-2016 DC74_RS16700 0a9a8f0b020f8e64af20024f0e41c343 368 Gene3D G3DSA:3.30.160.20 227 305 1.0E-35 T 23-04-2016 IPR014720 Double-stranded RNA-binding domain DC74_RS16700 0a9a8f0b020f8e64af20024f0e41c343 368 SUPERFAMILY SSF75620 31 365 2.09E-121 T 23-04-2016 DC74_RS16700 0a9a8f0b020f8e64af20024f0e41c343 368 Pfam PF00472 RF-1 domain 228 336 3.6E-38 T 23-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 SUPERFAMILY SSF51735 8 222 1.27E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 PANTHER PTHR24320:SF45 1 302 4.9E-116 T 23-04-2016 DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 Pfam PF00106 short chain dehydrogenase 16 218 7.3E-31 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 Gene3D G3DSA:3.40.50.720 5 248 2.8E-58 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 1.8E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 1.8E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 176 195 1.8E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 9.1E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 9.1E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 9.1E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 9.1E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 9.1E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14735 19fe4e72d43733772d007e84f33a13de 312 PANTHER PTHR24320 1 302 4.9E-116 T 23-04-2016 DC74_RS33085 640e589f003f4c4fa1f62e5fd70c2647 305 PANTHER PTHR36151:SF3 25 296 1.4E-66 T 23-04-2016 DC74_RS33085 640e589f003f4c4fa1f62e5fd70c2647 305 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 29 265 3.1E-53 T 23-04-2016 IPR018713 Domain of unknown function DUF2236 DC74_RS33085 640e589f003f4c4fa1f62e5fd70c2647 305 PANTHER PTHR36151 25 296 1.4E-66 T 23-04-2016 DC74_RS16610 6ba96f06e902c8f8d1f8736e1fdfb379 448 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 8 440 3.9E-131 T 23-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS16610 6ba96f06e902c8f8d1f8736e1fdfb379 448 SUPERFAMILY SSF55205 8 442 2.45E-112 T 23-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 DC74_RS16610 6ba96f06e902c8f8d1f8736e1fdfb379 448 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 12 432 8.0E-59 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 DC74_RS16610 6ba96f06e902c8f8d1f8736e1fdfb379 448 Gene3D G3DSA:3.65.10.10 230 440 6.3E-49 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 DC74_RS16610 6ba96f06e902c8f8d1f8736e1fdfb379 448 PANTHER PTHR21090 6 357 1.6E-136 T 23-04-2016 DC74_RS16610 6ba96f06e902c8f8d1f8736e1fdfb379 448 PANTHER PTHR21090 374 440 1.6E-136 T 23-04-2016 DC74_RS16610 6ba96f06e902c8f8d1f8736e1fdfb379 448 Gene3D G3DSA:3.65.10.10 26 229 2.1E-52 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 DC74_RS13625 7fbc45b1d0ef7e951b7b4d8a962340af 278 Pfam PF07398 MDMPI C-terminal domain 165 269 6.9E-14 T 23-04-2016 IPR010872 MDMPI C-terminal DC74_RS13625 7fbc45b1d0ef7e951b7b4d8a962340af 278 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 27 251 1.4E-23 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS13625 7fbc45b1d0ef7e951b7b4d8a962340af 278 SUPERFAMILY SSF109854 19 158 1.44E-9 T 23-04-2016 DC74_RS13625 7fbc45b1d0ef7e951b7b4d8a962340af 278 PANTHER PTHR40758 15 278 9.2E-65 T 23-04-2016 DC74_RS13625 7fbc45b1d0ef7e951b7b4d8a962340af 278 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 25 152 6.3E-22 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS22355 240ef5ac281ea828d5e9f95110460ad6 169 Pfam PF13581 Histidine kinase-like ATPase domain 36 162 6.9E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS22355 240ef5ac281ea828d5e9f95110460ad6 169 SUPERFAMILY SSF55874 64 156 4.4E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32830 d7c4f42bf9790afb9e5c6e081eabaf64 247 Pfam PF00005 ABC transporter 21 173 4.2E-15 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS32830 d7c4f42bf9790afb9e5c6e081eabaf64 247 SMART SM00382 30 222 8.5E-6 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS32830 d7c4f42bf9790afb9e5c6e081eabaf64 247 Gene3D G3DSA:3.40.50.300 4 229 2.2E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32830 d7c4f42bf9790afb9e5c6e081eabaf64 247 PANTHER PTHR24220 3 230 3.6E-38 T 23-04-2016 DC74_RS32830 d7c4f42bf9790afb9e5c6e081eabaf64 247 SUPERFAMILY SSF52540 3 229 4.93E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 555 1.2E-93 T 23-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 PANTHER PTHR22594:SF5 2 303 1.2E-210 T 23-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 PANTHER PTHR22594:SF5 367 569 1.2E-210 T 23-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 516 530 1.3E-21 T 23-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 1.3E-21 T 23-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 1.3E-21 T 23-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 472 488 1.3E-21 T 23-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 PANTHER PTHR22594 2 303 1.2E-210 T 23-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 PANTHER PTHR22594 367 569 1.2E-210 T 23-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 Gene3D G3DSA:3.30.930.10 410 582 1.2E-95 T 23-04-2016 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 Gene3D G3DSA:3.30.930.10 136 282 1.2E-95 T 23-04-2016 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 SUPERFAMILY SSF50249 4 107 4.5E-27 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 580 8.8E-186 T 23-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 4 561 32.694 T 23-04-2016 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 Pfam PF02938 GAD domain 315 403 2.8E-20 T 23-04-2016 IPR029351 GAD domain DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 Pfam PF01336 OB-fold nucleic acid binding domain 21 104 1.5E-15 T 23-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 Gene3D G3DSA:3.30.1360.30 283 409 5.6E-42 T 23-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 SUPERFAMILY SSF55681 422 582 4.21E-93 T 23-04-2016 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 SUPERFAMILY SSF55681 118 298 4.21E-93 T 23-04-2016 DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 Gene3D G3DSA:2.40.50.140 4 108 4.7E-33 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS20250 5f0820e31543e25b3185538f2cce511a 595 SUPERFAMILY SSF55261 296 414 8.5E-35 T 23-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 DC74_RS20255 a0e53e4826d9a7e46d70f10c0b29b51b 728 Gene3D G3DSA:3.30.450.20 3 111 3.6E-7 T 23-04-2016 DC74_RS20255 a0e53e4826d9a7e46d70f10c0b29b51b 728 SUPERFAMILY SSF81606 334 493 2.88E-6 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS20255 a0e53e4826d9a7e46d70f10c0b29b51b 728 Pfam PF13185 GAF domain 172 290 1.7E-10 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS20255 a0e53e4826d9a7e46d70f10c0b29b51b 728 SMART SM00331 318 559 6.4E-37 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS20255 a0e53e4826d9a7e46d70f10c0b29b51b 728 PANTHER PTHR21021 241 568 1.5E-56 T 23-04-2016 DC74_RS20255 a0e53e4826d9a7e46d70f10c0b29b51b 728 SUPERFAMILY SSF55781 155 303 8.29E-15 T 23-04-2016 IPR029016 GAF domain-like DC74_RS20255 a0e53e4826d9a7e46d70f10c0b29b51b 728 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 347 559 2.0E-47 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS20255 a0e53e4826d9a7e46d70f10c0b29b51b 728 Gene3D G3DSA:3.30.450.40 135 293 3.9E-14 T 23-04-2016 IPR029016 GAF domain-like DC74_RS20255 a0e53e4826d9a7e46d70f10c0b29b51b 728 PANTHER PTHR21021:SF19 241 568 1.5E-56 T 23-04-2016 DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 SMART SM00760 521 590 3.8E-36 T 23-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 Pfam PF00308 Bacterial dnaA protein 275 492 7.3E-104 T 23-04-2016 IPR013317 Chromosomal replication initiator protein DnaA DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 SUPERFAMILY SSF48295 517 613 5.49E-34 T 23-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 3 612 32.66 T 23-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 PANTHER PTHR30050 275 614 6.3E-196 T 23-04-2016 DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 PANTHER PTHR30050:SF2 275 614 6.3E-196 T 23-04-2016 DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 524 590 2.0E-29 T 23-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 Gene3D G3DSA:1.10.1750.10 516 613 1.7E-38 T 23-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 Gene3D G3DSA:3.40.50.300 272 439 1.4E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 Gene3D G3DSA:1.10.8.60 441 510 1.9E-28 T 23-04-2016 DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 270 611 9.8E-150 T 23-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 ProSitePatterns PS01008 DnaA protein signature. 571 590 - T 23-04-2016 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 SMART SM00382 307 435 2.2E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 SUPERFAMILY SSF52540 274 486 9.21E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 571 590 5.3E-52 T 23-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 372 386 5.3E-52 T 23-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 308 328 5.3E-52 T 23-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 340 354 5.3E-52 T 23-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like DC74_RS20690 a986ec00ce1099058e12b4d249162fae 614 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 406 433 5.3E-52 T 23-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like DC74_RS00760 7a6f609afb613728afc4dc31c059a607 555 Pfam PF16861 Carbamoyltransferase C-terminus 396 534 7.9E-43 T 23-04-2016 IPR031730 Carbamoyltransferase, C-terminal DC74_RS00760 7a6f609afb613728afc4dc31c059a607 555 PANTHER PTHR34847 1 539 2.3E-63 T 23-04-2016 DC74_RS00760 7a6f609afb613728afc4dc31c059a607 555 Pfam PF02543 Carbamoyltransferase N-terminus 3 344 1.1E-53 T 23-04-2016 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 DC74_RS00760 7a6f609afb613728afc4dc31c059a607 555 SUPERFAMILY SSF53067 126 205 3.63E-7 T 23-04-2016 DC74_RS00760 7a6f609afb613728afc4dc31c059a607 555 SUPERFAMILY SSF53067 242 345 3.63E-7 T 23-04-2016 DC74_RS00760 7a6f609afb613728afc4dc31c059a607 555 SUPERFAMILY SSF53067 18 77 3.63E-7 T 23-04-2016 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Gene3D G3DSA:1.10.1030.10 406 538 1.2E-45 T 23-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 SUPERFAMILY SSF52440 558 678 5.32E-43 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 SMART SM00851 974 1065 9.1E-28 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 430 547 1.4E-36 T 23-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 303 332 9.9E-63 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 385 403 9.9E-63 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 9.9E-63 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 9.9E-63 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 210 229 9.9E-63 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 174 186 9.9E-63 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 245 262 9.9E-63 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 SMART SM01096 426 547 7.0E-62 T 23-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 303 310 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 170 184 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Gene3D G3DSA:3.30.470.20 206 405 7.2E-77 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Gene3D G3DSA:3.30.470.20 750 952 3.2E-60 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1086 12.961 T 23-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 SUPERFAMILY SSF52335 960 1094 3.4E-32 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 SUPERFAMILY SSF52440 2 127 1.12E-46 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 SUPERFAMILY SSF56059 678 951 1.52E-88 T 23-04-2016 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 SUPERFAMILY SSF56059 128 406 5.66E-100 T 23-04-2016 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 713 727 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Gene3D G3DSA:3.40.50.1380 957 1096 3.5E-40 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1074 0.0 T 23-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 SUPERFAMILY SSF48108 402 553 6.15E-46 T 23-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Gene3D G3DSA:3.30.1490.20 149 205 1.0E-18 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Gene3D G3DSA:3.30.1490.20 690 749 3.3E-24 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Gene3D G3DSA:3.40.50.20 539 666 9.0E-57 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 PANTHER PTHR11405:SF5 1 1092 0.0 T 23-04-2016 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 340 9.0E-67 T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 680 879 1.4E-30 T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 842 849 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Gene3D G3DSA:3.40.50.20 3 107 2.8E-42 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 Pfam PF02142 MGS-like domain 975 1065 4.8E-21 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain DC74_RS09435 a6f807116fe6e02bc625ec0cd49a8f30 1103 PANTHER PTHR11405 1 1092 0.0 T 23-04-2016 DC74_RS06570 30f4519ec95c69087c462623cbcd870f 230 PIRSF PIRSF006171 1 230 1.5E-78 T 23-04-2016 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 DC74_RS06570 30f4519ec95c69087c462623cbcd870f 230 Pfam PF00072 Response regulator receiver domain 4 115 3.5E-24 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS06570 30f4519ec95c69087c462623cbcd870f 230 Gene3D G3DSA:3.40.50.2300 2 123 1.1E-28 T 23-04-2016 DC74_RS06570 30f4519ec95c69087c462623cbcd870f 230 SUPERFAMILY SSF52172 3 126 5.12E-33 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS06570 30f4519ec95c69087c462623cbcd870f 230 Gene3D G3DSA:1.10.10.10 165 210 9.2E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06570 30f4519ec95c69087c462623cbcd870f 230 SMART SM00448 2 115 1.0E-27 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS06570 30f4519ec95c69087c462623cbcd870f 230 Pfam PF09339 IclR helix-turn-helix domain 171 206 1.2E-6 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS06570 30f4519ec95c69087c462623cbcd870f 230 PANTHER PTHR26402 2 199 2.7E-72 T 23-04-2016 DC74_RS06570 30f4519ec95c69087c462623cbcd870f 230 PANTHER PTHR26402:SF434 2 199 2.7E-72 T 23-04-2016 DC74_RS06570 30f4519ec95c69087c462623cbcd870f 230 SUPERFAMILY SSF46785 168 212 6.07E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08385 a002f37bba0add8f2df0e5402b142f23 348 PANTHER PTHR18919 1 347 9.7E-57 T 23-04-2016 DC74_RS08385 a002f37bba0add8f2df0e5402b142f23 348 PANTHER PTHR18919:SF102 1 347 9.7E-57 T 23-04-2016 DC74_RS08385 a002f37bba0add8f2df0e5402b142f23 348 SUPERFAMILY SSF53901 9 128 3.03E-12 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS08385 a002f37bba0add8f2df0e5402b142f23 348 SUPERFAMILY SSF53901 188 215 3.03E-12 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS08385 a002f37bba0add8f2df0e5402b142f23 348 Gene3D G3DSA:3.40.47.10 244 330 4.6E-6 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS08385 a002f37bba0add8f2df0e5402b142f23 348 SUPERFAMILY SSF53901 220 336 2.25E-13 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS08385 a002f37bba0add8f2df0e5402b142f23 348 Gene3D G3DSA:3.40.47.10 31 136 4.4E-5 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS08385 a002f37bba0add8f2df0e5402b142f23 348 Gene3D G3DSA:3.40.47.10 191 211 4.4E-5 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 SUPERFAMILY SSF52151 518 646 1.36E-71 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 SUPERFAMILY SSF52151 707 806 1.36E-71 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8 255 2.3E-81 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 Gene3D G3DSA:3.30.70.250 644 705 5.1E-9 T 23-04-2016 DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 263 380 2.1E-39 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 383 497 8.6E-17 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 SUPERFAMILY SSF53901 6 375 9.34E-89 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 522 814 2.1E-113 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 Gene3D G3DSA:3.40.47.10 268 433 8.1E-59 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 SUPERFAMILY SSF55048 645 706 1.12E-10 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 PANTHER PTHR11712:SF242 5 1167 0.0 T 23-04-2016 DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 PANTHER PTHR11712 5 1167 0.0 T 23-04-2016 DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 Gene3D G3DSA:3.40.47.10 10 267 5.5E-85 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 Pfam PF00698 Acyl transferase domain 522 832 1.6E-57 T 23-04-2016 IPR014043 Acyl transferase DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 SMART SM00825 Beta-ketoacyl synthase 10 433 5.3E-188 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 Gene3D G3DSA:3.40.366.10 706 817 5.6E-75 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 Gene3D G3DSA:3.40.366.10 514 640 5.6E-75 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 Pfam PF14765 Polyketide synthase dehydratase 877 1158 1.4E-44 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38745 4e47ab482b790ca113d340bc350ae2b9 1307 SMART SM00826 877 1054 8.7E-66 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS22205 89196e976664a9bb25c8875f224baefb 1078 Gene3D G3DSA:3.40.50.300 519 719 6.5E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22205 89196e976664a9bb25c8875f224baefb 1078 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 519 707 4.2E-51 T 23-04-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 DC74_RS22205 89196e976664a9bb25c8875f224baefb 1078 Gene3D G3DSA:1.20.1250.20 302 486 2.2E-13 T 23-04-2016 DC74_RS22205 89196e976664a9bb25c8875f224baefb 1078 PANTHER PTHR10344 91 905 0.0 T 23-04-2016 DC74_RS22205 89196e976664a9bb25c8875f224baefb 1078 SUPERFAMILY SSF103473 296 485 4.58E-11 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS22205 89196e976664a9bb25c8875f224baefb 1078 Pfam PF02223 Thymidylate kinase 524 707 3.6E-46 T 23-04-2016 DC74_RS22205 89196e976664a9bb25c8875f224baefb 1078 PANTHER PTHR10344:SF0 91 905 0.0 T 23-04-2016 DC74_RS22205 89196e976664a9bb25c8875f224baefb 1078 Hamap MF_00165 Thymidylate kinase [tmk]. 520 719 30.419 T 23-04-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 DC74_RS22205 89196e976664a9bb25c8875f224baefb 1078 SUPERFAMILY SSF52540 519 717 5.4E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22205 89196e976664a9bb25c8875f224baefb 1078 ProSitePatterns PS01331 Thymidylate kinase signature. 609 621 - T 23-04-2016 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 137 149 4.8E-51 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 11 24 4.8E-51 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 82 102 4.8E-51 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 274 283 4.8E-51 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 161 182 4.8E-51 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 103 122 4.8E-51 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 PANTHER PTHR11735:SF6 9 337 4.7E-138 T 23-04-2016 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 PANTHER PTHR11735 9 337 4.7E-138 T 23-04-2016 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 ProSitePatterns PS01016 Glycoprotease family signature. 102 122 - T 23-04-2016 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 10 324 5.8E-127 T 23-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 8 343 61.567 T 23-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 Pfam PF00814 Glycoprotease family 30 317 4.3E-98 T 23-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 Gene3D G3DSA:3.30.420.40 9 166 3.0E-46 T 23-04-2016 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 11 317 2.2E-98 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS18505 1efb1bc01a50922af494e204857a4387 385 SUPERFAMILY SSF53067 9 319 1.64E-38 T 23-04-2016 DC74_RS15280 37615ce0395e91076486af22c77ab055 137 SUPERFAMILY SSF54919 3 134 3.01E-52 T 23-04-2016 DC74_RS15280 37615ce0395e91076486af22c77ab055 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 31.843 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS15280 37615ce0395e91076486af22c77ab055 137 Gene3D G3DSA:3.30.70.141 3 134 4.1E-54 T 23-04-2016 DC74_RS15280 37615ce0395e91076486af22c77ab055 137 Pfam PF00334 Nucleoside diphosphate kinase 3 134 9.5E-52 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS15280 37615ce0395e91076486af22c77ab055 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.0E-41 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS15280 37615ce0395e91076486af22c77ab055 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.0E-41 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS15280 37615ce0395e91076486af22c77ab055 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 1.0E-41 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS15280 37615ce0395e91076486af22c77ab055 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.0E-41 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS15280 37615ce0395e91076486af22c77ab055 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.0E-41 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS15280 37615ce0395e91076486af22c77ab055 137 SMART SM00562 2 137 3.3E-72 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS15280 37615ce0395e91076486af22c77ab055 137 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 23-04-2016 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS15280 37615ce0395e91076486af22c77ab055 137 PANTHER PTHR11349 3 134 1.1E-64 T 23-04-2016 DC74_RS21420 c1133b8b102bd7a5400b8e694073a6df 182 SUPERFAMILY SSF55399 76 176 4.84E-23 T 23-04-2016 IPR023549 Subtilisin inhibitor GO:0004867 DC74_RS21420 c1133b8b102bd7a5400b8e694073a6df 182 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 86 167 1.0E-10 T 23-04-2016 IPR023549 Subtilisin inhibitor GO:0004867 DC74_RS21420 c1133b8b102bd7a5400b8e694073a6df 182 Pfam PF00720 Subtilisin inhibitor-like 77 156 1.2E-9 T 23-04-2016 IPR023549 Subtilisin inhibitor GO:0004867 DC74_RS21420 c1133b8b102bd7a5400b8e694073a6df 182 Gene3D G3DSA:3.30.350.10 74 175 2.3E-29 T 23-04-2016 IPR023549 Subtilisin inhibitor GO:0004867 DC74_RS26575 dc180f2a88a694b25093994569d912aa 259 Gene3D G3DSA:1.20.120.530 95 231 1.0E-29 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS26575 dc180f2a88a694b25093994569d912aa 259 SUPERFAMILY SSF46785 6 78 5.75E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26575 dc180f2a88a694b25093994569d912aa 259 PANTHER PTHR11751 4 111 7.2E-33 T 23-04-2016 DC74_RS26575 dc180f2a88a694b25093994569d912aa 259 Gene3D G3DSA:1.10.10.10 7 77 1.2E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26575 dc180f2a88a694b25093994569d912aa 259 PANTHER PTHR11751:SF342 4 111 7.2E-33 T 23-04-2016 DC74_RS26575 dc180f2a88a694b25093994569d912aa 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 6.8E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS26575 dc180f2a88a694b25093994569d912aa 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 6.8E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS26575 dc180f2a88a694b25093994569d912aa 259 SMART SM00345 15 74 7.6E-16 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS26575 dc180f2a88a694b25093994569d912aa 259 SUPERFAMILY SSF48008 95 228 3.14E-29 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS26575 dc180f2a88a694b25093994569d912aa 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 2.0E-15 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS26575 dc180f2a88a694b25093994569d912aa 259 SMART SM00895 95 222 2.0E-25 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS26575 dc180f2a88a694b25093994569d912aa 259 Pfam PF07729 FCD domain 95 221 5.5E-28 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS12470 9161a66e12daf54cf909c76874e872f2 342 Pfam PF00924 Mechanosensitive ion channel 134 331 8.8E-35 T 23-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 DC74_RS12470 9161a66e12daf54cf909c76874e872f2 342 PANTHER PTHR30566:SF10 4 341 4.7E-136 T 23-04-2016 DC74_RS12470 9161a66e12daf54cf909c76874e872f2 342 Gene3D G3DSA:2.30.30.60 195 243 1.8E-12 T 23-04-2016 DC74_RS12470 9161a66e12daf54cf909c76874e872f2 342 SUPERFAMILY SSF50182 179 244 3.27E-16 T 23-04-2016 IPR010920 LSM domain DC74_RS12470 9161a66e12daf54cf909c76874e872f2 342 PANTHER PTHR30566 4 341 4.7E-136 T 23-04-2016 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 PANTHER PTHR23115 80 441 5.9E-187 T 23-04-2016 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 PANTHER PTHR23115 466 609 5.9E-187 T 23-04-2016 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 PANTHER PTHR23115:SF184 80 441 5.9E-187 T 23-04-2016 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 PANTHER PTHR23115:SF184 466 609 5.9E-187 T 23-04-2016 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 27 72 3.5E-7 T 23-04-2016 IPR006847 Translation initiation factor IF-2, N-terminal DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 Gene3D G3DSA:2.40.30.10 515 612 2.9E-31 T 23-04-2016 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 109 269 4.9E-31 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 Pfam PF11987 Translation-initiation factor 2 402 503 1.2E-34 T 23-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 18 612 4.1E-230 T 23-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 Pfam PF00009 Elongation factor Tu GTP binding domain 111 271 5.6E-33 T 23-04-2016 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 SUPERFAMILY SSF52156 391 520 1.2E-36 T 23-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 SUPERFAMILY SSF50447 514 612 6.87E-26 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 Gene3D G3DSA:3.40.50.10050 412 492 8.5E-24 T 23-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 Gene3D G3DSA:2.40.30.10 282 376 4.8E-23 T 23-04-2016 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 Gene3D G3DSA:3.40.50.300 107 270 1.3E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 SUPERFAMILY SSF50447 283 367 1.67E-24 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 SMART SM00173 133 276 0.0076 T 23-04-2016 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 PRINTS PR00315 GTP-binding elongation factor signature 162 172 1.7E-10 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 PRINTS PR00315 GTP-binding elongation factor signature 110 123 1.7E-10 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 PRINTS PR00315 GTP-binding elongation factor signature 178 189 1.7E-10 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 PRINTS PR00315 GTP-binding elongation factor signature 214 223 1.7E-10 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 2 612 15.914 T 23-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 ProSitePatterns PS01176 Initiation factor 2 signature. 565 587 - T 23-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 DC74_RS28435 0331b8f5d55987f6686a2922fcb49e69 613 SUPERFAMILY SSF52540 103 273 1.31E-48 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11600 547904832a2b1b4a459aed21f0901290 357 PANTHER PTHR11601:SF31 14 355 1.9E-56 T 23-04-2016 DC74_RS11600 547904832a2b1b4a459aed21f0901290 357 Gene3D G3DSA:3.40.640.10 30 267 3.1E-30 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS11600 547904832a2b1b4a459aed21f0901290 357 Pfam PF00266 Aminotransferase class-V 17 205 3.0E-12 T 23-04-2016 IPR000192 Aminotransferase class V domain DC74_RS11600 547904832a2b1b4a459aed21f0901290 357 SUPERFAMILY SSF53383 14 355 5.33E-48 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS11600 547904832a2b1b4a459aed21f0901290 357 PANTHER PTHR11601 14 355 1.9E-56 T 23-04-2016 DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 PANTHER PTHR34218:SF2 327 748 1.4E-284 T 23-04-2016 DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 PANTHER PTHR34218:SF2 769 933 1.4E-284 T 23-04-2016 DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 PANTHER PTHR34218:SF2 19 281 1.4E-284 T 23-04-2016 DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 Gene3D G3DSA:3.60.20.10 754 771 8.0E-116 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 Gene3D G3DSA:3.60.20.10 331 412 8.0E-116 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 Gene3D G3DSA:3.60.20.10 504 709 8.0E-116 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 Pfam PF01804 Penicillin amidase 63 922 6.1E-249 T 23-04-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 SUPERFAMILY SSF56235 319 933 3.34E-216 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 SUPERFAMILY SSF56235 59 253 3.34E-216 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 PANTHER PTHR34218 327 748 1.4E-284 T 23-04-2016 DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 PANTHER PTHR34218 769 933 1.4E-284 T 23-04-2016 DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 PANTHER PTHR34218 19 281 1.4E-284 T 23-04-2016 DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 PIRSF PIRSF001227 20 933 1.3E-271 T 23-04-2016 IPR014395 Penicillin acylase GO:0016811 DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 Gene3D G3DSA:2.30.120.10 413 495 1.1E-26 T 23-04-2016 DC74_RS17855 49d34cf9acbf0ea09d05d5c7cc99255d 933 Gene3D G3DSA:1.10.439.10 47 223 5.5E-63 T 23-04-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 DC74_RS08635 ff4432b1b457454a8dfd9d2a5398cfc5 283 Gene3D G3DSA:1.10.3720.10 6 270 4.8E-46 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS08635 ff4432b1b457454a8dfd9d2a5398cfc5 283 PANTHER PTHR32243:SF11 5 283 3.9E-115 T 23-04-2016 DC74_RS08635 ff4432b1b457454a8dfd9d2a5398cfc5 283 PANTHER PTHR32243 5 283 3.9E-115 T 23-04-2016 DC74_RS08635 ff4432b1b457454a8dfd9d2a5398cfc5 283 SUPERFAMILY SSF161098 10 283 1.5E-50 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS08635 ff4432b1b457454a8dfd9d2a5398cfc5 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 269 2.7E-12 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26760 4e61e2f170678be4bce1d2b617ac0340 166 Pfam PF08534 Redoxin 21 162 1.6E-26 T 23-04-2016 IPR013740 Redoxin GO:0016491 DC74_RS26760 4e61e2f170678be4bce1d2b617ac0340 166 PANTHER PTHR10681 3 166 1.6E-48 T 23-04-2016 DC74_RS26760 4e61e2f170678be4bce1d2b617ac0340 166 SUPERFAMILY SSF52833 1 163 1.36E-41 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS26760 4e61e2f170678be4bce1d2b617ac0340 166 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 166 39.583 T 23-04-2016 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 DC74_RS26760 4e61e2f170678be4bce1d2b617ac0340 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 23-04-2016 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 DC74_RS26760 4e61e2f170678be4bce1d2b617ac0340 166 Gene3D G3DSA:3.40.30.10 2 166 1.8E-45 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS26760 4e61e2f170678be4bce1d2b617ac0340 166 PANTHER PTHR10681:SF81 3 166 1.6E-48 T 23-04-2016 DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 Gene3D G3DSA:2.30.38.10 332 411 4.6E-26 T 23-04-2016 DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 Gene3D G3DSA:3.40.50.980 176 330 2.8E-28 T 23-04-2016 DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 PANTHER PTHR24095 23 606 1.1E-182 T 23-04-2016 DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 Gene3D G3DSA:3.30.300.30 417 542 2.9E-36 T 23-04-2016 DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 SUPERFAMILY SSF47336 533 604 1.57E-19 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 SUPERFAMILY SSF56801 15 551 5.23E-135 T 23-04-2016 DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 Pfam PF13193 AMP-binding enzyme C-terminal domain 429 507 2.0E-11 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 ProSitePatterns PS00455 Putative AMP-binding domain signature. 165 176 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 Pfam PF00501 AMP-binding enzyme 28 421 1.0E-88 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 Pfam PF00550 Phosphopantetheine attachment site 542 604 1.8E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 Gene3D G3DSA:3.40.50.980 23 175 1.1E-41 T 23-04-2016 DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 48 445 1.1E-116 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 SMART SM00823 Phosphopantetheine attachment site 539 608 1.0E-10 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 ProSitePatterns PS00012 Phosphopantetheine attachment site. 563 578 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 Gene3D G3DSA:1.10.1200.10 543 609 1.3E-26 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05725 05ae32e696f445d99e497aef4bd5cf35 611 PANTHER PTHR24095:SF137 23 606 1.1E-182 T 23-04-2016 DC74_RS07560 070d427655068b735fafba10a5a7bfe7 403 Gene3D G3DSA:3.50.50.60 279 360 2.3E-36 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07560 070d427655068b735fafba10a5a7bfe7 403 Gene3D G3DSA:3.50.50.60 6 183 2.3E-36 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07560 070d427655068b735fafba10a5a7bfe7 403 PANTHER PTHR13789 1 384 1.0E-85 T 23-04-2016 DC74_RS07560 070d427655068b735fafba10a5a7bfe7 403 PANTHER PTHR13789:SF186 1 384 1.0E-85 T 23-04-2016 DC74_RS07560 070d427655068b735fafba10a5a7bfe7 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 1.9E-16 T 23-04-2016 DC74_RS07560 070d427655068b735fafba10a5a7bfe7 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.9E-16 T 23-04-2016 DC74_RS07560 070d427655068b735fafba10a5a7bfe7 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 1.9E-16 T 23-04-2016 DC74_RS07560 070d427655068b735fafba10a5a7bfe7 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 1.9E-16 T 23-04-2016 DC74_RS07560 070d427655068b735fafba10a5a7bfe7 403 SUPERFAMILY SSF51905 6 178 1.94E-56 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07560 070d427655068b735fafba10a5a7bfe7 403 SUPERFAMILY SSF51905 278 383 1.94E-56 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07560 070d427655068b735fafba10a5a7bfe7 403 Pfam PF01494 FAD binding domain 6 354 5.2E-21 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS26565 86c23e0bbb6e016015e4950adec12540 361 Gene3D G3DSA:1.20.58.340 285 361 3.1E-27 T 23-04-2016 DC74_RS26565 86c23e0bbb6e016015e4950adec12540 361 PANTHER PTHR21535 52 361 2.6E-65 T 23-04-2016 DC74_RS26565 86c23e0bbb6e016015e4950adec12540 361 Gene3D G3DSA:3.30.460.20 16 171 1.6E-42 T 23-04-2016 DC74_RS26565 86c23e0bbb6e016015e4950adec12540 361 Pfam PF01544 CorA-like Mg2+ transporter protein 63 357 1.7E-64 T 23-04-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 DC74_RS26565 86c23e0bbb6e016015e4950adec12540 361 PANTHER PTHR21535:SF33 52 361 2.6E-65 T 23-04-2016 DC74_RS26565 86c23e0bbb6e016015e4950adec12540 361 SUPERFAMILY SSF144083 297 358 9.15E-20 T 23-04-2016 DC74_RS26565 86c23e0bbb6e016015e4950adec12540 361 Gene3D G3DSA:1.20.58.340 172 283 3.6E-37 T 23-04-2016 DC74_RS26565 86c23e0bbb6e016015e4950adec12540 361 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 64 361 1.2E-61 T 23-04-2016 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 DC74_RS26565 86c23e0bbb6e016015e4950adec12540 361 SUPERFAMILY SSF143865 32 294 7.32E-65 T 23-04-2016 DC74_RS31560 ab6a602493bbe99f2c4577073d7fdc48 272 SUPERFAMILY SSF53474 4 261 3.78E-69 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31560 ab6a602493bbe99f2c4577073d7fdc48 272 PANTHER PTHR10992 4 263 2.2E-63 T 23-04-2016 DC74_RS31560 ab6a602493bbe99f2c4577073d7fdc48 272 Gene3D G3DSA:3.40.50.1820 3 262 4.1E-70 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31560 ab6a602493bbe99f2c4577073d7fdc48 272 PRINTS PR00412 Epoxide hydrolase signature 238 260 1.5E-12 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS31560 ab6a602493bbe99f2c4577073d7fdc48 272 PRINTS PR00412 Epoxide hydrolase signature 26 44 1.5E-12 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS31560 ab6a602493bbe99f2c4577073d7fdc48 272 PRINTS PR00412 Epoxide hydrolase signature 46 61 1.5E-12 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS31560 ab6a602493bbe99f2c4577073d7fdc48 272 PRINTS PR00412 Epoxide hydrolase signature 104 117 1.5E-12 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS31560 ab6a602493bbe99f2c4577073d7fdc48 272 Pfam PF12697 Alpha/beta hydrolase family 22 256 1.6E-20 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS31560 ab6a602493bbe99f2c4577073d7fdc48 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 4.5E-12 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS31560 ab6a602493bbe99f2c4577073d7fdc48 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 207 221 4.5E-12 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS31560 ab6a602493bbe99f2c4577073d7fdc48 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 4.5E-12 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS31560 ab6a602493bbe99f2c4577073d7fdc48 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 4.5E-12 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS26915 7946f23e4156970e786e2ed7bfd76bb3 264 Gene3D G3DSA:1.20.120.220 92 263 1.7E-38 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 DC74_RS26915 7946f23e4156970e786e2ed7bfd76bb3 264 Hamap MF_01393 ATP synthase subunit a [atpB]. 22 263 12.886 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 DC74_RS26915 7946f23e4156970e786e2ed7bfd76bb3 264 ProSitePatterns PS00449 ATP synthase a subunit signature. 188 197 - T 23-04-2016 IPR023011 ATPase, F0 complex, subunit A, active site DC74_RS26915 7946f23e4156970e786e2ed7bfd76bb3 264 SUPERFAMILY SSF81336 92 256 2.75E-34 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 DC74_RS26915 7946f23e4156970e786e2ed7bfd76bb3 264 Pfam PF00119 ATP synthase A chain 42 256 7.9E-49 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 DC74_RS26915 7946f23e4156970e786e2ed7bfd76bb3 264 PANTHER PTHR11410:SF7 5 264 4.5E-68 T 23-04-2016 DC74_RS26915 7946f23e4156970e786e2ed7bfd76bb3 264 PANTHER PTHR11410 5 264 4.5E-68 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 DC74_RS26915 7946f23e4156970e786e2ed7bfd76bb3 264 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 27 258 1.6E-41 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 DC74_RS26915 7946f23e4156970e786e2ed7bfd76bb3 264 PRINTS PR00123 ATP synthase A subunit signature 243 258 7.1E-16 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 DC74_RS26915 7946f23e4156970e786e2ed7bfd76bb3 264 PRINTS PR00123 ATP synthase A subunit signature 185 207 7.1E-16 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 DC74_RS26915 7946f23e4156970e786e2ed7bfd76bb3 264 PRINTS PR00123 ATP synthase A subunit signature 100 116 7.1E-16 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 DC74_RS09470 095d7fdda276a1ac31e0beff7b07dd73 145 SUPERFAMILY SSF48013 4 131 9.42E-41 T 23-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 DC74_RS09470 095d7fdda276a1ac31e0beff7b07dd73 145 PANTHER PTHR11078 3 143 6.6E-47 T 23-04-2016 IPR011605 NusB antitermination factor GO:0006353 DC74_RS09470 095d7fdda276a1ac31e0beff7b07dd73 145 Gene3D G3DSA:1.10.940.10 2 132 3.3E-44 T 23-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 DC74_RS09470 095d7fdda276a1ac31e0beff7b07dd73 145 Pfam PF01029 NusB family 6 132 7.6E-35 T 23-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 DC74_RS09470 095d7fdda276a1ac31e0beff7b07dd73 145 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 137 22.541 T 23-04-2016 IPR011605 NusB antitermination factor GO:0006353 DC74_RS09470 095d7fdda276a1ac31e0beff7b07dd73 145 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 133 4.9E-41 T 23-04-2016 IPR011605 NusB antitermination factor GO:0006353 DC74_RS04875 dc6c24f39fd6736ee6f6ab3e2403799b 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 8.1E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04875 dc6c24f39fd6736ee6f6ab3e2403799b 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 27 44 8.1E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04875 dc6c24f39fd6736ee6f6ab3e2403799b 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 222 8.1E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04875 dc6c24f39fd6736ee6f6ab3e2403799b 310 Pfam PF00106 short chain dehydrogenase 27 224 6.7E-30 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04875 dc6c24f39fd6736ee6f6ab3e2403799b 310 SUPERFAMILY SSF51735 23 274 1.64E-55 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04875 dc6c24f39fd6736ee6f6ab3e2403799b 310 PANTHER PTHR24320 7 307 1.9E-96 T 23-04-2016 DC74_RS04875 dc6c24f39fd6736ee6f6ab3e2403799b 310 Gene3D G3DSA:3.40.50.720 21 266 1.7E-56 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19800 a99cc82f36a95ba9d66fca69dde8b60d 452 SUPERFAMILY SSF53383 16 444 1.95E-118 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS19800 a99cc82f36a95ba9d66fca69dde8b60d 452 Gene3D G3DSA:3.40.640.10 69 321 2.7E-81 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS19800 a99cc82f36a95ba9d66fca69dde8b60d 452 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS19800 a99cc82f36a95ba9d66fca69dde8b60d 452 Gene3D G3DSA:3.90.1150.10 322 445 2.0E-31 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS19800 a99cc82f36a95ba9d66fca69dde8b60d 452 Pfam PF00202 Aminotransferase class-III 35 444 3.4E-99 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS19800 a99cc82f36a95ba9d66fca69dde8b60d 452 PANTHER PTHR11986 16 452 2.0E-144 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS36335 12c1ecc8e9afc34abffde86bd94e1119 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 225 6.1E-24 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS36335 12c1ecc8e9afc34abffde86bd94e1119 394 Gene3D G3DSA:1.10.540.10 9 126 2.7E-21 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS36335 12c1ecc8e9afc34abffde86bd94e1119 394 PANTHER PTHR10909:SF229 10 393 5.6E-141 T 23-04-2016 DC74_RS36335 12c1ecc8e9afc34abffde86bd94e1119 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 386 1.5E-29 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS36335 12c1ecc8e9afc34abffde86bd94e1119 394 Gene3D G3DSA:1.20.140.10 225 391 1.9E-27 T 23-04-2016 DC74_RS36335 12c1ecc8e9afc34abffde86bd94e1119 394 Gene3D G3DSA:2.40.110.10 130 224 2.3E-29 T 23-04-2016 DC74_RS36335 12c1ecc8e9afc34abffde86bd94e1119 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 125 1.5E-18 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS36335 12c1ecc8e9afc34abffde86bd94e1119 394 SUPERFAMILY SSF47203 237 388 3.74E-25 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS36335 12c1ecc8e9afc34abffde86bd94e1119 394 SUPERFAMILY SSF56645 13 248 3.14E-60 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS36335 12c1ecc8e9afc34abffde86bd94e1119 394 PANTHER PTHR10909 10 393 5.6E-141 T 23-04-2016 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 Pfam PF00486 Transcriptional regulatory protein, C terminal 38 87 3.6E-5 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 SUPERFAMILY SSF46894 13 89 1.19E-8 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 Pfam PF00931 NB-ARC domain 314 558 7.7E-9 T 23-04-2016 IPR002182 NB-ARC GO:0043531 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 PANTHER PTHR22845:SF4 163 635 2.0E-79 T 23-04-2016 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 SUPERFAMILY SSF48452 113 273 2.11E-36 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 Gene3D G3DSA:1.25.40.10 760 990 2.0E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 SMART SM01043 118 262 6.1E-48 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 PANTHER PTHR22845 163 635 2.0E-79 T 23-04-2016 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 SUPERFAMILY SSF48452 880 990 5.06E-10 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 PRINTS PR00364 Disease resistance protein signature 328 343 8.9E-9 T 23-04-2016 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 PRINTS PR00364 Disease resistance protein signature 489 503 8.9E-9 T 23-04-2016 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 PRINTS PR00364 Disease resistance protein signature 405 419 8.9E-9 T 23-04-2016 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 Gene3D G3DSA:3.40.50.300 308 420 2.3E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 Gene3D G3DSA:1.10.10.10 38 114 3.9E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 Gene3D G3DSA:1.25.40.10 127 245 1.3E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 SUPERFAMILY SSF52540 296 555 2.03E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 SMART SM00862 27 111 3.9E-6 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS05700 8e42676b29c51ce83bb425ed9b41ad7d 1002 Pfam PF03704 Bacterial transcriptional activator domain 118 262 6.4E-40 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS03365 0bd0da8e08f69934800b16fa9ff3f408 385 Pfam PF01494 FAD binding domain 16 59 1.2E-8 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS03365 0bd0da8e08f69934800b16fa9ff3f408 385 Pfam PF01494 FAD binding domain 143 326 5.0E-8 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS03365 0bd0da8e08f69934800b16fa9ff3f408 385 SUPERFAMILY SSF51905 16 172 6.79E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03365 0bd0da8e08f69934800b16fa9ff3f408 385 SUPERFAMILY SSF51905 271 345 6.79E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03365 0bd0da8e08f69934800b16fa9ff3f408 385 Gene3D G3DSA:3.30.9.10 167 320 3.8E-26 T 23-04-2016 DC74_RS03365 0bd0da8e08f69934800b16fa9ff3f408 385 Gene3D G3DSA:3.40.50.720 109 166 6.8E-18 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03365 0bd0da8e08f69934800b16fa9ff3f408 385 Gene3D G3DSA:3.40.50.720 16 67 6.8E-18 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03365 0bd0da8e08f69934800b16fa9ff3f408 385 PANTHER PTHR10617 17 317 6.4E-30 T 23-04-2016 DC74_RS03365 0bd0da8e08f69934800b16fa9ff3f408 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 17 39 1.5E-14 T 23-04-2016 DC74_RS03365 0bd0da8e08f69934800b16fa9ff3f408 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 1.5E-14 T 23-04-2016 DC74_RS03365 0bd0da8e08f69934800b16fa9ff3f408 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.5E-14 T 23-04-2016 DC74_RS30570 11583296fd4087322611e63c61c7c1d9 279 SUPERFAMILY SSF46785 120 207 3.8E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS30570 11583296fd4087322611e63c61c7c1d9 279 PANTHER PTHR33204:SF8 2 165 1.5E-70 T 23-04-2016 DC74_RS30570 11583296fd4087322611e63c61c7c1d9 279 Pfam PF01638 HxlR-like helix-turn-helix 24 109 2.3E-12 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS30570 11583296fd4087322611e63c61c7c1d9 279 PANTHER PTHR33204 2 165 1.5E-70 T 23-04-2016 DC74_RS30570 11583296fd4087322611e63c61c7c1d9 279 SUPERFAMILY SSF46785 13 109 2.53E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS30570 11583296fd4087322611e63c61c7c1d9 279 Gene3D G3DSA:1.10.10.10 15 110 3.9E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS30570 11583296fd4087322611e63c61c7c1d9 279 Gene3D G3DSA:1.10.10.10 118 207 5.7E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39700 96156aeb6193633092214c49cac75153 285 Pfam PF13560 Helix-turn-helix domain 5 81 3.4E-14 T 23-04-2016 DC74_RS39700 96156aeb6193633092214c49cac75153 285 PANTHER PTHR35010:SF2 1 278 6.1E-83 T 23-04-2016 DC74_RS39700 96156aeb6193633092214c49cac75153 285 Gene3D G3DSA:1.10.260.40 4 79 5.3E-19 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS39700 96156aeb6193633092214c49cac75153 285 PANTHER PTHR35010 1 278 6.1E-83 T 23-04-2016 DC74_RS39700 96156aeb6193633092214c49cac75153 285 SUPERFAMILY SSF47413 28 74 3.13E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS39700 96156aeb6193633092214c49cac75153 285 SMART SM00530 5 80 4.4E-4 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS29755 fa1bef832349c22d3d043deaf0375b89 495 PIRSF PIRSF006060 2 495 7.3E-93 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS29755 fa1bef832349c22d3d043deaf0375b89 495 Pfam PF13520 Amino acid permease 24 463 8.1E-54 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS29755 fa1bef832349c22d3d043deaf0375b89 495 PANTHER PTHR11785 240 488 1.1E-164 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS29755 fa1bef832349c22d3d043deaf0375b89 495 PANTHER PTHR11785 2 213 1.1E-164 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS29755 fa1bef832349c22d3d043deaf0375b89 495 PANTHER PTHR11785:SF342 240 488 1.1E-164 T 23-04-2016 DC74_RS29755 fa1bef832349c22d3d043deaf0375b89 495 PANTHER PTHR11785:SF342 2 213 1.1E-164 T 23-04-2016 DC74_RS01565 0fdbb6af51975dbf6d0c4485ede8ad04 256 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 13 137 8.7E-10 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS01565 0fdbb6af51975dbf6d0c4485ede8ad04 256 SUPERFAMILY SSF109854 11 137 9.16E-11 T 23-04-2016 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 SUPERFAMILY SSF82171 19 377 1.83E-30 T 23-04-2016 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 Gene3D G3DSA:3.40.50.1820 469 714 3.5E-76 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 PANTHER PTHR11731 409 717 3.2E-118 T 23-04-2016 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 PANTHER PTHR11731 82 384 3.2E-118 T 23-04-2016 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 PANTHER PTHR11731 22 41 3.2E-118 T 23-04-2016 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 554 584 - T 23-04-2016 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 577 597 5.6E-7 T 23-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 648 670 5.6E-7 T 23-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 519 543 5.6E-7 T 23-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 Pfam PF00326 Prolyl oligopeptidase family 513 715 5.7E-46 T 23-04-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 Pfam PF07676 WD40-like Beta Propeller Repeat 25 51 0.016 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 Gene3D G3DSA:2.140.10.30 19 392 2.9E-63 T 23-04-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 111 349 1.2E-29 T 23-04-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 PANTHER PTHR11731:SF110 409 717 3.2E-118 T 23-04-2016 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 PANTHER PTHR11731:SF110 82 384 3.2E-118 T 23-04-2016 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 PANTHER PTHR11731:SF110 22 41 3.2E-118 T 23-04-2016 DC74_RS25860 f8afd18b0bb17850cd0dce399ae65ffb 717 SUPERFAMILY SSF53474 468 715 1.99E-60 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS20235 2515b938674d135d5ac0fb0d67865ed1 426 Pfam PF00756 Putative esterase 144 362 1.9E-13 T 23-04-2016 IPR000801 Putative esterase DC74_RS20235 2515b938674d135d5ac0fb0d67865ed1 426 SUPERFAMILY SSF53474 141 377 1.48E-21 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS20235 2515b938674d135d5ac0fb0d67865ed1 426 Gene3D G3DSA:3.40.50.1820 123 383 3.4E-35 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS20235 2515b938674d135d5ac0fb0d67865ed1 426 PANTHER PTHR10907:SF33 149 295 2.2E-22 T 23-04-2016 DC74_RS20235 2515b938674d135d5ac0fb0d67865ed1 426 PANTHER PTHR10907 149 295 2.2E-22 T 23-04-2016 DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SUPERFAMILY SSF81901 34 138 2.35E-15 T 23-04-2016 DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Pfam PF08238 Sel1 repeat 107 138 0.62 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Pfam PF08238 Sel1 repeat 359 375 8.7 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Pfam PF08238 Sel1 repeat 377 407 0.004 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Pfam PF08238 Sel1 repeat 222 246 3.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Pfam PF08238 Sel1 repeat 157 169 6.8 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Pfam PF08238 Sel1 repeat 440 479 9.6E-4 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Pfam PF08238 Sel1 repeat 250 279 0.65 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Pfam PF08238 Sel1 repeat 528 543 1.1 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Pfam PF08238 Sel1 repeat 171 215 3.6E-4 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Pfam PF08238 Sel1 repeat 494 511 7.3 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SUPERFAMILY SSF81901 465 577 4.97E-20 T 23-04-2016 DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Pfam PF13432 Tetratricopeptide repeat 285 340 0.0023 T 23-04-2016 DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 440 479 27.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 376 407 0.18 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 107 138 0.053 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 139 169 39.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 512 543 1.5 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 75 106 220.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 43 74 35.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 312 343 47.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 480 511 22.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 248 279 0.62 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 170 215 40.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 216 247 25.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 280 311 30.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SMART SM00671 344 375 16.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 SUPERFAMILY SSF81901 262 449 7.85E-27 T 23-04-2016 DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 PANTHER PTHR11102:SF11 226 423 1.1E-49 T 23-04-2016 DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Gene3D G3DSA:1.25.40.10 196 406 6.9E-44 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Gene3D G3DSA:1.25.40.10 34 184 5.5E-27 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 PANTHER PTHR11102:SF11 461 553 1.1E-49 T 23-04-2016 DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Gene3D G3DSA:1.25.40.10 465 581 3.4E-19 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 Pfam PF13374 Tetratricopeptide repeat 44 71 0.013 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 PANTHER PTHR11102 226 423 1.1E-49 T 23-04-2016 DC74_RS26285 2206143bc8a4ba6fd4599c69e71b5a96 595 PANTHER PTHR11102 461 553 1.1E-49 T 23-04-2016 DC74_RS24940 babcb9cfbd4cd90497faaccb50d7e83c 135 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 16 105 2.3E-9 T 23-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 DC74_RS24940 babcb9cfbd4cd90497faaccb50d7e83c 135 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 61 101 - T 23-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 DC74_RS24940 babcb9cfbd4cd90497faaccb50d7e83c 135 SUPERFAMILY SSF53927 10 133 3.01E-38 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS24940 babcb9cfbd4cd90497faaccb50d7e83c 135 Gene3D G3DSA:3.40.140.10 10 134 5.5E-41 T 23-04-2016 DC74_RS24940 babcb9cfbd4cd90497faaccb50d7e83c 135 PANTHER PTHR11644 9 135 4.6E-44 T 23-04-2016 DC74_RS39495 690c3b579b04b2bc380a1c37cfdc5cea 536 SUPERFAMILY SSF52467 183 339 2.4E-54 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS39495 690c3b579b04b2bc380a1c37cfdc5cea 536 Gene3D G3DSA:3.40.50.970 6 169 1.4E-38 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS39495 690c3b579b04b2bc380a1c37cfdc5cea 536 SUPERFAMILY SSF52518 7 169 5.16E-34 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS39495 690c3b579b04b2bc380a1c37cfdc5cea 536 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 382 527 5.6E-26 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS39495 690c3b579b04b2bc380a1c37cfdc5cea 536 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 169 7.6E-38 T 23-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DC74_RS39495 690c3b579b04b2bc380a1c37cfdc5cea 536 PANTHER PTHR18968:SF133 1 529 7.0E-181 T 23-04-2016 DC74_RS39495 690c3b579b04b2bc380a1c37cfdc5cea 536 SUPERFAMILY SSF52518 348 532 2.86E-42 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS39495 690c3b579b04b2bc380a1c37cfdc5cea 536 Gene3D G3DSA:3.40.50.1220 181 333 1.6E-40 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS39495 690c3b579b04b2bc380a1c37cfdc5cea 536 Gene3D G3DSA:3.40.50.970 348 533 1.1E-45 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS39495 690c3b579b04b2bc380a1c37cfdc5cea 536 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 324 1.3E-19 T 23-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DC74_RS39495 690c3b579b04b2bc380a1c37cfdc5cea 536 PANTHER PTHR18968 1 529 7.0E-181 T 23-04-2016 DC74_RS36425 1830319109e07a7334fa4b49c4c5f2d1 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 82 7.5E-9 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS36425 1830319109e07a7334fa4b49c4c5f2d1 389 Gene3D G3DSA:2.40.110.10 110 196 4.3E-30 T 23-04-2016 DC74_RS36425 1830319109e07a7334fa4b49c4c5f2d1 389 PANTHER PTHR10909:SF275 13 363 2.2E-93 T 23-04-2016 DC74_RS36425 1830319109e07a7334fa4b49c4c5f2d1 389 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 235 367 6.8E-36 T 23-04-2016 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain DC74_RS36425 1830319109e07a7334fa4b49c4c5f2d1 389 Gene3D G3DSA:1.20.140.10 197 387 9.7E-48 T 23-04-2016 DC74_RS36425 1830319109e07a7334fa4b49c4c5f2d1 389 Gene3D G3DSA:1.10.540.10 2 107 4.1E-43 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS36425 1830319109e07a7334fa4b49c4c5f2d1 389 SUPERFAMILY SSF47203 225 367 2.47E-15 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS36425 1830319109e07a7334fa4b49c4c5f2d1 389 PANTHER PTHR10909 13 363 2.2E-93 T 23-04-2016 DC74_RS36425 1830319109e07a7334fa4b49c4c5f2d1 389 SUPERFAMILY SSF56645 8 204 1.02E-39 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS36425 1830319109e07a7334fa4b49c4c5f2d1 389 PIRSF PIRSF016578 1 389 5.9E-134 T 23-04-2016 DC74_RS10645 b293074bb958e52695887c762ec3b5bb 1352 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 931 1091 5.2E-27 T 23-04-2016 DC74_RS10645 b293074bb958e52695887c762ec3b5bb 1352 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1152 1332 2.4E-15 T 23-04-2016 DC74_RS10645 b293074bb958e52695887c762ec3b5bb 1352 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 709 870 2.3E-29 T 23-04-2016 DC74_RS10645 b293074bb958e52695887c762ec3b5bb 1352 Gene3D G3DSA:2.60.120.200 920 1095 4.9E-32 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS10645 b293074bb958e52695887c762ec3b5bb 1352 SUPERFAMILY SSF49899 1104 1335 2.19E-17 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS10645 b293074bb958e52695887c762ec3b5bb 1352 SUPERFAMILY SSF49899 665 876 3.05E-35 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS10645 b293074bb958e52695887c762ec3b5bb 1352 SMART SM00560 948 1089 1.2E-8 T 23-04-2016 IPR006558 LamG-like jellyroll fold DC74_RS10645 b293074bb958e52695887c762ec3b5bb 1352 SMART SM00560 726 868 9.3E-22 T 23-04-2016 IPR006558 LamG-like jellyroll fold DC74_RS10645 b293074bb958e52695887c762ec3b5bb 1352 SUPERFAMILY SSF49899 909 1096 1.22E-26 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS10645 b293074bb958e52695887c762ec3b5bb 1352 Gene3D G3DSA:2.60.120.200 1102 1334 4.1E-18 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS10645 b293074bb958e52695887c762ec3b5bb 1352 Gene3D G3DSA:2.60.120.200 653 874 3.9E-38 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 267 343 2.3E-15 T 23-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 SMART SM00322 579 643 7.6E-12 T 23-04-2016 IPR004087 K Homology domain GO:0003676 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 PANTHER PTHR11252 1 740 0.0 T 23-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 SUPERFAMILY SSF55666 474 573 2.13E-24 T 23-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 SUPERFAMILY SSF54791 576 688 2.13E-19 T 23-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 SUPERFAMILY SSF54211 6 151 3.09E-46 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 Pfam PF00575 S1 RNA binding domain 648 718 8.5E-12 T 23-04-2016 IPR003029 S1 domain GO:0003676 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 Pfam PF00013 KH domain 583 639 4.8E-11 T 23-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 SUPERFAMILY SSF46915 264 344 1.78E-16 T 23-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 Gene3D G3DSA:3.30.1370.10 579 652 1.3E-23 T 23-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 SUPERFAMILY SSF54211 321 492 1.21E-41 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 Gene3D G3DSA:1.10.10.400 263 335 5.9E-23 T 23-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 Gene3D G3DSA:3.30.230.70 8 249 1.2E-84 T 23-04-2016 IPR027408 PNPase/RNase PH domain DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 Gene3D G3DSA:3.30.230.70 336 570 1.0E-80 T 23-04-2016 IPR027408 PNPase/RNase PH domain DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 PANTHER PTHR11252:SF0 1 740 0.0 T 23-04-2016 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 SMART SM00316 649 723 4.1E-17 T 23-04-2016 IPR022967 RNA-binding domain, S1 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 Pfam PF01138 3' exoribonuclease family, domain 1 348 480 6.3E-14 T 23-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 Pfam PF01138 3' exoribonuclease family, domain 1 20 151 7.9E-18 T 23-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 SUPERFAMILY SSF55666 152 260 3.44E-29 T 23-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 PIRSF PIRSF005499 7 740 5.4E-284 T 23-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 5 722 0.0 T 23-04-2016 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 17 720 6.0E-262 T 23-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 9 726 26.912 T 23-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 DC74_RS28575 c098b943d71dac7240bc8e06d2147107 740 Gene3D G3DSA:2.40.50.140 653 720 9.4E-17 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS33000 ccb4d85525b0c279352bdded993ba480 244 Pfam PF02308 MgtC family 23 151 8.0E-37 T 23-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 DC74_RS33000 ccb4d85525b0c279352bdded993ba480 244 PANTHER PTHR33778 17 168 6.3E-50 T 23-04-2016 DC74_RS33000 ccb4d85525b0c279352bdded993ba480 244 PRINTS PR01837 MgtC/SapB protein signature 45 63 4.0E-43 T 23-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 DC74_RS33000 ccb4d85525b0c279352bdded993ba480 244 PRINTS PR01837 MgtC/SapB protein signature 79 101 4.0E-43 T 23-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 DC74_RS33000 ccb4d85525b0c279352bdded993ba480 244 PRINTS PR01837 MgtC/SapB protein signature 26 45 4.0E-43 T 23-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 DC74_RS33000 ccb4d85525b0c279352bdded993ba480 244 PRINTS PR01837 MgtC/SapB protein signature 106 130 4.0E-43 T 23-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 DC74_RS23145 783d51f07582a74ce95c01c85f8c15ed 195 PANTHER PTHR15854:SF6 2 167 5.3E-86 T 23-04-2016 DC74_RS23145 783d51f07582a74ce95c01c85f8c15ed 195 SUPERFAMILY SSF50814 7 165 5.41E-43 T 23-04-2016 IPR011038 Calycin-like DC74_RS23145 783d51f07582a74ce95c01c85f8c15ed 195 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 4 166 32.471 T 23-04-2016 IPR022939 Uncharacterised protein family UPF0678 DC74_RS23145 783d51f07582a74ce95c01c85f8c15ed 195 PANTHER PTHR15854 2 167 5.3E-86 T 23-04-2016 DC74_RS23145 783d51f07582a74ce95c01c85f8c15ed 195 Pfam PF08768 Domain of unknown function (DUF1794) 12 164 1.8E-50 T 23-04-2016 IPR014878 Domain of unknown function DUF1794 DC74_RS39725 fdac61577d9c4369e03b47f961034488 405 PANTHER PTHR10909 8 380 9.6E-139 T 23-04-2016 DC74_RS39725 fdac61577d9c4369e03b47f961034488 405 SUPERFAMILY SSF47203 242 403 3.06E-18 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS39725 fdac61577d9c4369e03b47f961034488 405 Gene3D G3DSA:2.40.110.10 139 217 6.3E-13 T 23-04-2016 DC74_RS39725 fdac61577d9c4369e03b47f961034488 405 PIRSF PIRSF016578 7 399 2.9E-29 T 23-04-2016 DC74_RS39725 fdac61577d9c4369e03b47f961034488 405 SUPERFAMILY SSF56645 28 221 3.27E-37 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS39725 fdac61577d9c4369e03b47f961034488 405 Gene3D G3DSA:1.10.540.10 10 115 3.6E-30 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS39725 fdac61577d9c4369e03b47f961034488 405 Gene3D G3DSA:1.20.140.10 232 404 3.4E-54 T 23-04-2016 DC74_RS39725 fdac61577d9c4369e03b47f961034488 405 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 245 379 9.2E-16 T 23-04-2016 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain DC74_RS39725 fdac61577d9c4369e03b47f961034488 405 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 29 116 4.6E-7 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS39725 fdac61577d9c4369e03b47f961034488 405 PANTHER PTHR10909:SF274 8 380 9.6E-139 T 23-04-2016 DC74_RS37105 de832b14fde82ae789f86f651118348b 545 PANTHER PTHR19211 317 524 5.4E-128 T 23-04-2016 DC74_RS37105 de832b14fde82ae789f86f651118348b 545 PANTHER PTHR19211 16 287 5.4E-128 T 23-04-2016 DC74_RS37105 de832b14fde82ae789f86f651118348b 545 Gene3D G3DSA:3.40.50.300 367 523 7.5E-35 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37105 de832b14fde82ae789f86f651118348b 545 Pfam PF00005 ABC transporter 26 194 7.8E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS37105 de832b14fde82ae789f86f651118348b 545 Pfam PF00005 ABC transporter 368 494 2.9E-22 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS37105 de832b14fde82ae789f86f651118348b 545 SUPERFAMILY SSF52540 368 527 3.58E-36 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37105 de832b14fde82ae789f86f651118348b 545 SUPERFAMILY SSF52540 16 239 1.01E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37105 de832b14fde82ae789f86f651118348b 545 SMART SM00382 375 539 2.3E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS37105 de832b14fde82ae789f86f651118348b 545 SMART SM00382 35 239 6.8E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS37105 de832b14fde82ae789f86f651118348b 545 Gene3D G3DSA:3.40.50.300 140 276 3.6E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37105 de832b14fde82ae789f86f651118348b 545 Gene3D G3DSA:3.40.50.300 11 107 3.6E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37105 de832b14fde82ae789f86f651118348b 545 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 19 903 0.0 T 23-04-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 Gene3D G3DSA:3.40.50.920 730 902 3.1E-68 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 Gene3D G3DSA:3.40.50.970 488 726 1.8E-109 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 PANTHER PTHR11624:SF67 487 548 0.0 T 23-04-2016 DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 PANTHER PTHR11624:SF67 87 308 0.0 T 23-04-2016 DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 PANTHER PTHR11624 377 466 0.0 T 23-04-2016 IPR033247 Transketolase family DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 PIRSF PIRSF000156 10 910 0.0 T 23-04-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 PANTHER PTHR11624 569 790 0.0 T 23-04-2016 IPR033247 Transketolase family DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 SUPERFAMILY SSF52518 70 482 8.11E-125 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 SUPERFAMILY SSF52922 726 900 3.49E-53 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 PANTHER PTHR11624:SF67 569 790 0.0 T 23-04-2016 DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 PANTHER PTHR11624:SF67 809 892 0.0 T 23-04-2016 DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 PANTHER PTHR11624 809 892 0.0 T 23-04-2016 IPR033247 Transketolase family DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 PANTHER PTHR11624 487 548 0.0 T 23-04-2016 IPR033247 Transketolase family DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 PANTHER PTHR11624 87 308 0.0 T 23-04-2016 IPR033247 Transketolase family DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 Gene3D G3DSA:3.40.50.970 70 483 1.8E-146 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 PANTHER PTHR11624:SF67 377 466 0.0 T 23-04-2016 DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 150 307 4.0E-9 T 23-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS13955 b1c3f6d8a3a49c1cc1b0b0d01bf2ae94 915 SUPERFAMILY SSF52518 488 722 7.36E-86 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS04830 3c4a23ab26bda411b4b9cbd08715e232 442 PANTHER PTHR19372 283 441 3.2E-100 T 23-04-2016 DC74_RS04830 3c4a23ab26bda411b4b9cbd08715e232 442 SUPERFAMILY SSF56524 306 441 3.01E-29 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS04830 3c4a23ab26bda411b4b9cbd08715e232 442 PANTHER PTHR19372 15 267 3.2E-100 T 23-04-2016 DC74_RS04830 3c4a23ab26bda411b4b9cbd08715e232 442 Pfam PF00174 Oxidoreductase molybdopterin binding domain 310 441 1.6E-20 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS04830 3c4a23ab26bda411b4b9cbd08715e232 442 PANTHER PTHR19372:SF2 15 267 3.2E-100 T 23-04-2016 DC74_RS04830 3c4a23ab26bda411b4b9cbd08715e232 442 Gene3D G3DSA:3.90.420.10 300 441 6.1E-28 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS04830 3c4a23ab26bda411b4b9cbd08715e232 442 PANTHER PTHR19372:SF2 283 441 3.2E-100 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 444 450 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 ProSitePatterns PS01047 Heavy-metal-associated domain. 14 42 - T 23-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 ProSitePatterns PS01229 Hypothetical cof family signature 2. 644 666 - T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 207 747 1.7E-149 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 SUPERFAMILY SSF81653 248 342 4.71E-25 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 Gene3D G3DSA:3.40.50.1000 572 712 1.4E-49 T 23-04-2016 IPR023214 HAD-like domain DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 Gene3D G3DSA:3.40.50.1000 413 457 1.4E-49 T 23-04-2016 IPR023214 HAD-like domain DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 Pfam PF00702 haloacid dehalogenase-like hydrolase 438 658 6.6E-46 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 Pfam PF00403 Heavy-metal-associated domain 13 72 2.3E-15 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 SUPERFAMILY SSF56784 440 460 3.96E-54 T 23-04-2016 IPR023214 HAD-like domain DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 SUPERFAMILY SSF56784 501 744 3.96E-54 T 23-04-2016 IPR023214 HAD-like domain DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 644 660 1.1E-7 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 616 632 1.1E-7 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 675 700 1.1E-7 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 Gene3D G3DSA:2.70.150.10 210 343 6.1E-28 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 PANTHER PTHR24093:SF50 10 750 8.7E-237 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 SUPERFAMILY SSF81665 693 715 4.05E-10 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 SUPERFAMILY SSF81665 230 246 4.05E-10 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 SUPERFAMILY SSF81665 343 436 4.05E-10 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 SUPERFAMILY SSF55008 9 78 4.19E-17 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 Gene3D G3DSA:3.40.1110.10 458 571 1.4E-17 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 PANTHER PTHR24093 10 750 8.7E-237 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 Gene3D G3DSA:3.30.70.100 10 75 1.8E-21 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 591 601 2.0E-22 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 667 679 2.0E-22 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 442 456 2.0E-22 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 292 306 2.0E-22 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 663 2.0E-22 T 23-04-2016 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 216 463 5.4E-43 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 550 725 2.1E-36 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 Pfam PF00122 E1-E2 ATPase 215 433 3.7E-65 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS26550 f3c13fa7f0f1ca2157f46eb5ab763c4a 753 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 161 746 4.7E-175 T 23-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 753 771 5.0E-51 T 23-04-2016 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 619 635 5.0E-51 T 23-04-2016 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 700 719 5.0E-51 T 23-04-2016 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 730 749 5.0E-51 T 23-04-2016 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 374 393 5.0E-51 T 23-04-2016 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 PANTHER PTHR10046:SF24 1 803 0.0 T 23-04-2016 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 703 711 - T 23-04-2016 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 Gene3D G3DSA:3.40.50.300 312 518 6.5E-33 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 SMART SM00464 12 205 7.0E-22 T 23-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 SUPERFAMILY SSF88697 12 204 2.73E-25 T 23-04-2016 IPR015947 PUA-like domain DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 PIRSF PIRSF001174 1 801 2.1E-243 T 23-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 12 203 6.1E-18 T 23-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 SMART SM00382 366 511 8.6E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 SUPERFAMILY SSF52540 312 596 1.74E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 SUPERFAMILY SSF54211 619 797 4.17E-53 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 Gene3D G3DSA:1.10.8.60 519 601 1.5E-25 T 23-04-2016 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 Hamap MF_01973 Lon protease [lon]. 13 799 58.882 T 23-04-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 Gene3D G3DSA:3.30.230.10 614 798 3.6E-70 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 371 506 8.5E-20 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 TIGRFAM TIGR00763 lon: endopeptidase La 14 798 3.4E-238 T 23-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 593 799 1.8E-75 T 23-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 DC74_RS26710 d4e265b9f2fff6f6733a977d9319672c 813 PANTHER PTHR10046 1 803 0.0 T 23-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 DC74_RS27690 864b20ab38d5549c20eba1fde12416b0 174 Gene3D G3DSA:3.30.70.260 1 78 2.7E-33 T 23-04-2016 DC74_RS27690 864b20ab38d5549c20eba1fde12416b0 174 Gene3D G3DSA:3.30.70.1150 84 163 2.5E-31 T 23-04-2016 DC74_RS27690 864b20ab38d5549c20eba1fde12416b0 174 PANTHER PTHR30239 3 172 2.3E-88 T 23-04-2016 DC74_RS27690 864b20ab38d5549c20eba1fde12416b0 174 SUPERFAMILY SSF55021 81 161 2.32E-26 T 23-04-2016 DC74_RS27690 864b20ab38d5549c20eba1fde12416b0 174 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 1.6E-60 T 23-04-2016 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS27690 864b20ab38d5549c20eba1fde12416b0 174 Pfam PF13710 ACT domain 13 74 7.3E-16 T 23-04-2016 DC74_RS27690 864b20ab38d5549c20eba1fde12416b0 174 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 3.0E-34 T 23-04-2016 DC74_RS27690 864b20ab38d5549c20eba1fde12416b0 174 SUPERFAMILY SSF55021 3 75 8.08E-22 T 23-04-2016 DC74_RS27690 864b20ab38d5549c20eba1fde12416b0 174 Pfam PF10369 Small subunit of acetolactate synthase 85 158 3.0E-29 T 23-04-2016 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS22030 82187ae8a232636078f73b83d0f26186 154 PANTHER PTHR11803:SF2 4 154 1.5E-50 T 23-04-2016 DC74_RS22030 82187ae8a232636078f73b83d0f26186 154 Gene3D G3DSA:3.30.1330.40 3 152 3.5E-68 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS22030 82187ae8a232636078f73b83d0f26186 154 SUPERFAMILY SSF55298 3 152 8.8E-56 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS22030 82187ae8a232636078f73b83d0f26186 154 PANTHER PTHR11803 4 154 1.5E-50 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS22030 82187ae8a232636078f73b83d0f26186 154 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 152 7.2E-32 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS34790 70ef4763fa67fbea09a64b6733104489 392 Gene3D G3DSA:3.40.50.1100 144 386 6.0E-44 T 23-04-2016 DC74_RS34790 70ef4763fa67fbea09a64b6733104489 392 PANTHER PTHR10314 59 381 2.5E-49 T 23-04-2016 DC74_RS34790 70ef4763fa67fbea09a64b6733104489 392 SUPERFAMILY SSF53686 65 384 2.1E-64 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS34790 70ef4763fa67fbea09a64b6733104489 392 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 66 374 2.0E-61 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS34790 70ef4763fa67fbea09a64b6733104489 392 PANTHER PTHR10314:SF5 59 381 2.5E-49 T 23-04-2016 DC74_RS32860 ae193993e121c1844c77553d06ab8784 333 Gene3D G3DSA:3.40.50.300 56 258 2.0E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32860 ae193993e121c1844c77553d06ab8784 333 SUPERFAMILY SSF52540 4 325 1.18E-91 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32860 ae193993e121c1844c77553d06ab8784 333 Pfam PF03308 ArgK protein 22 294 2.3E-111 T 23-04-2016 DC74_RS32860 ae193993e121c1844c77553d06ab8784 333 Gene3D G3DSA:1.20.5.170 4 55 1.8E-22 T 23-04-2016 DC74_RS32860 ae193993e121c1844c77553d06ab8784 333 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 17 321 1.7E-113 T 23-04-2016 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 DC74_RS32860 ae193993e121c1844c77553d06ab8784 333 PANTHER PTHR23408:SF17 7 325 6.3E-153 T 23-04-2016 DC74_RS32860 ae193993e121c1844c77553d06ab8784 333 PANTHER PTHR23408 7 325 6.3E-153 T 23-04-2016 DC74_RS04975 126f3c657abbc14363cfdaa37f451cd9 223 SUPERFAMILY SSF50090 1 221 1.88E-56 T 23-04-2016 IPR008990 Electron transport accessory protein-like domain DC74_RS04975 126f3c657abbc14363cfdaa37f451cd9 223 TIGRFAM TIGR03888 nitrile_beta: nitrile hydratase, beta subunit 1 221 5.1E-54 T 23-04-2016 IPR003168 Nitrile hydratase, beta subunit GO:0006807|GO:0018822|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 DC74_RS04975 126f3c657abbc14363cfdaa37f451cd9 223 Gene3D G3DSA:1.10.472.20 1 138 6.3E-30 T 23-04-2016 DC74_RS04975 126f3c657abbc14363cfdaa37f451cd9 223 PIRSF PIRSF001427 1 222 2.3E-56 T 23-04-2016 IPR003168 Nitrile hydratase, beta subunit GO:0006807|GO:0018822|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 DC74_RS04975 126f3c657abbc14363cfdaa37f451cd9 223 Gene3D G3DSA:2.30.30.50 139 221 6.1E-33 T 23-04-2016 DC74_RS04975 126f3c657abbc14363cfdaa37f451cd9 223 Pfam PF02211 Nitrile hydratase beta subunit 1 220 9.5E-65 T 23-04-2016 IPR024690 Nitrile hydratase beta subunit domain GO:0018822 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 DC74_RS01975 c391400e107d4a6b8e494727a8bd38ce 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 139 3.4E-30 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS01975 c391400e107d4a6b8e494727a8bd38ce 346 Pfam PF00107 Zinc-binding dehydrogenase 182 304 5.9E-22 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS01975 c391400e107d4a6b8e494727a8bd38ce 346 Gene3D G3DSA:3.90.180.10 1 174 3.3E-51 T 23-04-2016 IPR011032 GroES-like DC74_RS01975 c391400e107d4a6b8e494727a8bd38ce 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS01975 c391400e107d4a6b8e494727a8bd38ce 346 PANTHER PTHR11695:SF280 13 345 2.0E-99 T 23-04-2016 DC74_RS01975 c391400e107d4a6b8e494727a8bd38ce 346 SUPERFAMILY SSF51735 142 312 1.47E-32 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01975 c391400e107d4a6b8e494727a8bd38ce 346 PANTHER PTHR11695 13 345 2.0E-99 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS01975 c391400e107d4a6b8e494727a8bd38ce 346 SUPERFAMILY SSF50129 1 187 4.72E-44 T 23-04-2016 IPR011032 GroES-like DC74_RS01975 c391400e107d4a6b8e494727a8bd38ce 346 Gene3D G3DSA:3.40.50.720 175 278 7.7E-26 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01975 c391400e107d4a6b8e494727a8bd38ce 346 SMART SM00829 10 342 1.4E-5 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS09590 f7f15d585ee2ba5fe686528a7bc5b078 182 Pfam PF00156 Phosphoribosyl transferase domain 34 156 5.4E-16 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 DC74_RS09590 f7f15d585ee2ba5fe686528a7bc5b078 182 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 12 169 2.8E-61 T 23-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 DC74_RS09590 f7f15d585ee2ba5fe686528a7bc5b078 182 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 11 182 36.212 T 23-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 DC74_RS09590 f7f15d585ee2ba5fe686528a7bc5b078 182 PANTHER PTHR32315 1 169 3.1E-74 T 23-04-2016 DC74_RS09590 f7f15d585ee2ba5fe686528a7bc5b078 182 Gene3D G3DSA:3.40.50.2020 8 181 1.2E-64 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS09590 f7f15d585ee2ba5fe686528a7bc5b078 182 SUPERFAMILY SSF53271 14 168 6.11E-50 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS21485 1070817d7102f539338e53004431987f 201 PANTHER PTHR30543 1 178 7.2E-38 T 23-04-2016 DC74_RS21485 1070817d7102f539338e53004431987f 201 SUPERFAMILY SSF52218 2 172 2.1E-31 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS21485 1070817d7102f539338e53004431987f 201 PANTHER PTHR30543:SF6 1 178 7.2E-38 T 23-04-2016 DC74_RS21485 1070817d7102f539338e53004431987f 201 Gene3D G3DSA:3.40.50.360 1 176 8.7E-39 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS21485 1070817d7102f539338e53004431987f 201 Pfam PF03358 NADPH-dependent FMN reductase 3 139 1.6E-27 T 23-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 DC74_RS24535 7285ea867acfeab5788f10b7ad39f724 323 PANTHER PTHR30173:SF17 6 184 2.5E-26 T 23-04-2016 DC74_RS24535 7285ea867acfeab5788f10b7ad39f724 323 PANTHER PTHR30173 6 184 2.5E-26 T 23-04-2016 DC74_RS24535 7285ea867acfeab5788f10b7ad39f724 323 SUPERFAMILY SSF88946 28 98 7.46E-6 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS24535 7285ea867acfeab5788f10b7ad39f724 323 Gene3D G3DSA:1.10.1740.10 29 99 5.8E-6 T 23-04-2016 DC74_RS24535 7285ea867acfeab5788f10b7ad39f724 323 SUPERFAMILY SSF88659 125 181 5.49E-6 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS24535 7285ea867acfeab5788f10b7ad39f724 323 Gene3D G3DSA:1.10.10.10 125 183 7.4E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26740 c20d42f1f39a918b86da6bb51b3054f4 141 PANTHER PTHR36222 1 140 3.0E-46 T 23-04-2016 DC74_RS26740 c20d42f1f39a918b86da6bb51b3054f4 141 Gene3D G3DSA:3.30.450.30 50 125 1.4E-9 T 23-04-2016 DC74_RS26740 c20d42f1f39a918b86da6bb51b3054f4 141 SUPERFAMILY SSF103196 1 129 7.85E-19 T 23-04-2016 DC74_RS26740 c20d42f1f39a918b86da6bb51b3054f4 141 SMART SM00960 2 101 9.4E-11 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS26740 c20d42f1f39a918b86da6bb51b3054f4 141 Pfam PF03259 Roadblock/LC7 domain 50 99 1.5E-7 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS08330 3cea8436453b65cd964149fd969b2517 377 Pfam PF00534 Glycosyl transferases group 1 196 347 1.0E-26 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 DC74_RS08330 3cea8436453b65cd964149fd969b2517 377 PANTHER PTHR12526 1 370 7.1E-73 T 23-04-2016 DC74_RS08330 3cea8436453b65cd964149fd969b2517 377 Pfam PF13439 Glycosyltransferase Family 4 14 184 2.8E-23 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain DC74_RS08330 3cea8436453b65cd964149fd969b2517 377 PANTHER PTHR12526:SF363 1 370 7.1E-73 T 23-04-2016 DC74_RS08330 3cea8436453b65cd964149fd969b2517 377 Gene3D G3DSA:3.40.50.2000 174 347 3.5E-27 T 23-04-2016 DC74_RS08330 3cea8436453b65cd964149fd969b2517 377 SUPERFAMILY SSF53756 1 369 2.24E-75 T 23-04-2016 DC74_RS06785 3aa91c2cd826f5a6f102a52640f1c42f 352 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 346 1.1E-99 T 23-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase DC74_RS06785 3aa91c2cd826f5a6f102a52640f1c42f 352 PANTHER PTHR30244:SF16 1 352 5.8E-118 T 23-04-2016 DC74_RS06785 3aa91c2cd826f5a6f102a52640f1c42f 352 SUPERFAMILY SSF53383 5 349 1.01E-101 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS06785 3aa91c2cd826f5a6f102a52640f1c42f 352 PANTHER PTHR30244 1 352 5.8E-118 T 23-04-2016 DC74_RS06785 3aa91c2cd826f5a6f102a52640f1c42f 352 Gene3D G3DSA:3.90.1150.10 237 350 8.0E-18 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS06785 3aa91c2cd826f5a6f102a52640f1c42f 352 PIRSF PIRSF000390 1 351 2.0E-96 T 23-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase DC74_RS06785 3aa91c2cd826f5a6f102a52640f1c42f 352 Gene3D G3DSA:3.40.640.10 6 234 2.0E-78 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 PANTHER PTHR21021 467 772 1.9E-58 T 23-04-2016 DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 Gene3D G3DSA:3.30.450.20 49 184 6.0E-42 T 23-04-2016 DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 Pfam PF13581 Histidine kinase-like ATPase domain 777 884 4.2E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 Pfam PF17203 Single cache domain 3 52 186 2.3E-23 T 23-04-2016 IPR033463 Single cache domain 3 DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 Pfam PF13185 GAF domain 363 516 8.6E-9 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 Gene3D G3DSA:3.30.450.20 227 329 4.2E-6 T 23-04-2016 DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 Gene3D G3DSA:3.30.450.40 347 523 2.9E-36 T 23-04-2016 IPR029016 GAF domain-like DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 SUPERFAMILY SSF81606 557 762 1.12E-10 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 SMART SM00065 349 525 1.9E-7 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 SUPERFAMILY SSF103190 54 183 2.12E-31 T 23-04-2016 IPR029151 Periplasmic sensor domain-like DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 SMART SM00331 543 763 4.7E-38 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 571 763 2.2E-54 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 SUPERFAMILY SSF55781 400 519 2.18E-15 T 23-04-2016 IPR029016 GAF domain-like DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 PANTHER PTHR21021:SF19 467 772 1.9E-58 T 23-04-2016 DC74_RS06395 316744ba0d0adda9d1235f38becce354 907 SUPERFAMILY SSF55874 807 885 6.88E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 Gene3D G3DSA:3.40.710.10 45 301 1.6E-98 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 PRINTS PR00118 Beta-lactamase class A signature 217 232 9.0E-68 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 PRINTS PR00118 Beta-lactamase class A signature 119 144 9.0E-68 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 PRINTS PR00118 Beta-lactamase class A signature 78 95 9.0E-68 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 PRINTS PR00118 Beta-lactamase class A signature 47 71 9.0E-68 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 PRINTS PR00118 Beta-lactamase class A signature 155 179 9.0E-68 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 PRINTS PR00118 Beta-lactamase class A signature 181 206 9.0E-68 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 PRINTS PR00118 Beta-lactamase class A signature 234 249 9.0E-68 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 SUPERFAMILY SSF56601 44 298 1.38E-74 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 PANTHER PTHR35333:SF2 24 302 5.3E-91 T 23-04-2016 DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 Pfam PF13354 Beta-lactamase enzyme family 68 274 1.6E-36 T 23-04-2016 DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 ProSitePatterns PS00146 Beta-lactamase class-A active site. 80 95 - T 23-04-2016 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 DC74_RS06195 ce08ca7711a8ea1694457a3f1785021a 305 PANTHER PTHR35333 24 302 5.3E-91 T 23-04-2016 DC74_RS28885 e398fa6a1d1ee07820f78fdee6b830f5 544 Pfam PF01433 Peptidase family M1 83 393 5.3E-33 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS28885 e398fa6a1d1ee07820f78fdee6b830f5 544 Gene3D G3DSA:1.10.390.10 363 505 4.6E-17 T 23-04-2016 DC74_RS28885 e398fa6a1d1ee07820f78fdee6b830f5 544 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 194 209 1.8E-10 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS28885 e398fa6a1d1ee07820f78fdee6b830f5 544 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 349 364 1.8E-10 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS28885 e398fa6a1d1ee07820f78fdee6b830f5 544 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 368 380 1.8E-10 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS28885 e398fa6a1d1ee07820f78fdee6b830f5 544 PANTHER PTHR11533 1 505 2.9E-128 T 23-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 DC74_RS28885 e398fa6a1d1ee07820f78fdee6b830f5 544 SUPERFAMILY SSF63737 68 257 2.35E-34 T 23-04-2016 DC74_RS28885 e398fa6a1d1ee07820f78fdee6b830f5 544 SUPERFAMILY SSF55486 267 504 2.01E-47 T 23-04-2016 DC74_RS28885 e398fa6a1d1ee07820f78fdee6b830f5 544 PANTHER PTHR11533:SF185 1 505 2.9E-128 T 23-04-2016 DC74_RS23850 0804c3fc7560151574fbadf9ad76ed9d 299 PANTHER PTHR22911 4 299 2.2E-66 T 23-04-2016 DC74_RS23850 0804c3fc7560151574fbadf9ad76ed9d 299 PANTHER PTHR22911:SF37 4 299 2.2E-66 T 23-04-2016 DC74_RS23850 0804c3fc7560151574fbadf9ad76ed9d 299 SUPERFAMILY SSF103481 60 153 2.48E-6 T 23-04-2016 DC74_RS23850 0804c3fc7560151574fbadf9ad76ed9d 299 Pfam PF00892 EamA-like transporter family 161 291 1.9E-12 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS23850 0804c3fc7560151574fbadf9ad76ed9d 299 SUPERFAMILY SSF103481 202 297 1.57E-6 T 23-04-2016 DC74_RS37040 37640cfb476cb416319a5278291dec96 260 PANTHER PTHR35005:SF1 3 250 9.5E-28 T 23-04-2016 DC74_RS37040 37640cfb476cb416319a5278291dec96 260 Gene3D G3DSA:3.40.50.10310 12 250 7.2E-60 T 23-04-2016 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167|UniPathway: UPA00071|UniPathway: UPA00275 DC74_RS37040 37640cfb476cb416319a5278291dec96 260 Pfam PF02633 Creatinine amidohydrolase 14 247 1.8E-47 T 23-04-2016 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167|UniPathway: UPA00071|UniPathway: UPA00275 DC74_RS37040 37640cfb476cb416319a5278291dec96 260 SUPERFAMILY SSF102215 15 248 9.68E-57 T 23-04-2016 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167|UniPathway: UPA00071|UniPathway: UPA00275 DC74_RS37040 37640cfb476cb416319a5278291dec96 260 PANTHER PTHR35005 3 250 9.5E-28 T 23-04-2016 DC74_RS03090 e0e71ae893bc8b7124b85c80ceda4d01 300 Pfam PF03466 LysR substrate binding domain 88 294 2.7E-31 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS03090 e0e71ae893bc8b7124b85c80ceda4d01 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.96E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS03090 e0e71ae893bc8b7124b85c80ceda4d01 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.96E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS03090 e0e71ae893bc8b7124b85c80ceda4d01 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.96E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS03090 e0e71ae893bc8b7124b85c80ceda4d01 300 Gene3D G3DSA:1.10.10.10 1 86 5.0E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03090 e0e71ae893bc8b7124b85c80ceda4d01 300 Gene3D G3DSA:3.40.190.10 88 191 5.6E-13 T 23-04-2016 DC74_RS03090 e0e71ae893bc8b7124b85c80ceda4d01 300 SUPERFAMILY SSF53850 90 295 6.11E-28 T 23-04-2016 DC74_RS03090 e0e71ae893bc8b7124b85c80ceda4d01 300 Gene3D G3DSA:3.40.190.10 192 266 1.6E-12 T 23-04-2016 DC74_RS03090 e0e71ae893bc8b7124b85c80ceda4d01 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.6E-23 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS03090 e0e71ae893bc8b7124b85c80ceda4d01 300 SUPERFAMILY SSF46785 1 84 7.23E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03090 e0e71ae893bc8b7124b85c80ceda4d01 300 PANTHER PTHR30346 1 294 2.5E-60 T 23-04-2016 DC74_RS38050 46aaa12b8275d5c388307e57bb275b37 370 PANTHER PTHR11228 33 323 2.9E-22 T 23-04-2016 DC74_RS38050 46aaa12b8275d5c388307e57bb275b37 370 Pfam PF04055 Radical SAM superfamily 40 190 2.3E-15 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS38050 46aaa12b8275d5c388307e57bb275b37 370 SUPERFAMILY SSF102114 33 321 8.44E-31 T 23-04-2016 DC74_RS38050 46aaa12b8275d5c388307e57bb275b37 370 Gene3D G3DSA:3.20.20.70 31 334 2.0E-29 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS20785 b9bc07be77550f8ca0e547981daf4a5f 360 PANTHER PTHR11510 4 356 1.3E-143 T 23-04-2016 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|UniPathway: UPA00823 DC74_RS20785 b9bc07be77550f8ca0e547981daf4a5f 360 Gene3D G3DSA:3.40.50.720 1 189 1.7E-115 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20785 b9bc07be77550f8ca0e547981daf4a5f 360 Gene3D G3DSA:3.40.50.720 301 355 1.7E-115 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20785 b9bc07be77550f8ca0e547981daf4a5f 360 Pfam PF01658 Myo-inositol-1-phosphate synthase 191 300 6.8E-32 T 23-04-2016 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|UniPathway: UPA00823 DC74_RS20785 b9bc07be77550f8ca0e547981daf4a5f 360 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 4 354 4.8E-222 T 23-04-2016 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria DC74_RS20785 b9bc07be77550f8ca0e547981daf4a5f 360 PIRSF PIRSF015578 1 359 7.5E-92 T 23-04-2016 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|UniPathway: UPA00823 DC74_RS20785 b9bc07be77550f8ca0e547981daf4a5f 360 Gene3D G3DSA:3.30.360.10 190 300 7.7E-48 T 23-04-2016 DC74_RS20785 b9bc07be77550f8ca0e547981daf4a5f 360 SUPERFAMILY SSF51735 3 185 7.88E-92 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20785 b9bc07be77550f8ca0e547981daf4a5f 360 SUPERFAMILY SSF51735 297 356 7.88E-92 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20785 b9bc07be77550f8ca0e547981daf4a5f 360 SUPERFAMILY SSF55347 190 299 1.44E-34 T 23-04-2016 DC74_RS20785 b9bc07be77550f8ca0e547981daf4a5f 360 PANTHER PTHR11510:SF9 4 356 1.3E-143 T 23-04-2016 DC74_RS04765 4642ce7d424e99864caf319d6969837f 79 Gene3D G3DSA:3.30.70.20 1 63 4.7E-13 T 23-04-2016 DC74_RS04765 4642ce7d424e99864caf319d6969837f 79 SUPERFAMILY SSF54862 1 60 2.97E-11 T 23-04-2016 DC74_RS04765 4642ce7d424e99864caf319d6969837f 79 PANTHER PTHR36923 1 70 9.4E-14 T 23-04-2016 DC74_RS04765 4642ce7d424e99864caf319d6969837f 79 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 3.2E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS04765 4642ce7d424e99864caf319d6969837f 79 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 3.2E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS04765 4642ce7d424e99864caf319d6969837f 79 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 3.2E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS04765 4642ce7d424e99864caf319d6969837f 79 Pfam PF13459 4Fe-4S single cluster domain 4 60 7.4E-12 T 23-04-2016 DC74_RS38665 7c2095e67d05af1ff49d58eb85fbdb52 185 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 106 121 5.3E-14 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS38665 7c2095e67d05af1ff49d58eb85fbdb52 185 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 64 72 5.3E-14 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS38665 7c2095e67d05af1ff49d58eb85fbdb52 185 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 144 160 5.3E-14 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS38665 7c2095e67d05af1ff49d58eb85fbdb52 185 TIGRFAM TIGR00077 lspA: signal peptidase II 19 163 1.3E-24 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS38665 7c2095e67d05af1ff49d58eb85fbdb52 185 PANTHER PTHR33695:SF1 1 167 3.5E-39 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS38665 7c2095e67d05af1ff49d58eb85fbdb52 185 Pfam PF01252 Signal peptidase (SPase) II 25 163 5.5E-28 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS38665 7c2095e67d05af1ff49d58eb85fbdb52 185 PANTHER PTHR33695 1 167 3.5E-39 T 23-04-2016 DC74_RS38665 7c2095e67d05af1ff49d58eb85fbdb52 185 ProSitePatterns PS00855 Signal peptidases II signature. 109 121 - T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS38665 7c2095e67d05af1ff49d58eb85fbdb52 185 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 17 169 13.983 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 PANTHER PTHR11070 1 567 0.0 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 Pfam PF00580 UvrD/REP helicase N-terminal domain 5 76 1.9E-19 T 23-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 Pfam PF00580 UvrD/REP helicase N-terminal domain 158 267 3.6E-26 T 23-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 Gene3D G3DSA:3.40.50.300 3 273 6.7E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 SMART SM00341 631 721 6.7E-10 T 23-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 Gene3D G3DSA:1.10.150.80 634 698 7.1E-12 T 23-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 PANTHER PTHR11070:SF21 1 567 0.0 T 23-04-2016 DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 SUPERFAMILY SSF52540 3 567 2.28E-117 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 Gene3D G3DSA:3.40.50.300 279 392 5.2E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 Gene3D G3DSA:3.40.50.300 484 567 5.2E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 SUPERFAMILY SSF47819 624 703 2.4E-19 T 23-04-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 Pfam PF13361 UvrD-like helicase C-terminal domain 275 391 5.7E-13 T 23-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 Pfam PF13361 UvrD-like helicase C-terminal domain 439 546 4.8E-24 T 23-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 DC74_RS26195 03c101dc1631c172ad5bdd0cc7424d99 728 Pfam PF00570 HRDC domain 635 700 3.4E-19 T 23-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 DC74_RS27390 987084e51d3ca0853fd570a00574aa79 294 PANTHER PTHR31272:SF4 3 230 1.8E-47 T 23-04-2016 DC74_RS27390 987084e51d3ca0853fd570a00574aa79 294 PANTHER PTHR31272 3 230 1.8E-47 T 23-04-2016 DC74_RS27390 987084e51d3ca0853fd570a00574aa79 294 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 10 182 3.1E-22 T 23-04-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 DC74_RS18110 4940de1b03fe5a4f0694a107015948da 288 Pfam PF13560 Helix-turn-helix domain 13 69 2.7E-17 T 23-04-2016 DC74_RS18110 4940de1b03fe5a4f0694a107015948da 288 PANTHER PTHR10245:SF20 4 284 6.8E-104 T 23-04-2016 DC74_RS18110 4940de1b03fe5a4f0694a107015948da 288 SMART SM00530 17 72 3.4E-13 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS18110 4940de1b03fe5a4f0694a107015948da 288 Gene3D G3DSA:1.10.260.40 6 73 7.7E-19 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS18110 4940de1b03fe5a4f0694a107015948da 288 SUPERFAMILY SSF47413 7 73 1.23E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS18110 4940de1b03fe5a4f0694a107015948da 288 PANTHER PTHR10245 4 284 6.8E-104 T 23-04-2016 DC74_RS35270 f9822398681b1d1e40109181b822c93e 220 Gene3D G3DSA:3.40.50.1860 38 106 5.3E-4 T 23-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS08310 0666c21ad8fd72dc4134049d690b04e6 1206 PANTHER PTHR11365 1 1204 0.0 T 23-04-2016 DC74_RS08310 0666c21ad8fd72dc4134049d690b04e6 1206 Pfam PF02538 Hydantoinase B/oxoprolinase 699 1204 9.8E-196 T 23-04-2016 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 DC74_RS08310 0666c21ad8fd72dc4134049d690b04e6 1206 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 7 185 2.5E-57 T 23-04-2016 IPR008040 Hydantoinaseoxoprolinase, N-terminal DC74_RS08310 0666c21ad8fd72dc4134049d690b04e6 1206 Pfam PF01968 Hydantoinase/oxoprolinase 205 499 1.5E-106 T 23-04-2016 IPR002821 Hydantoinase/oxoprolinase GO:0016787 DC74_RS08310 0666c21ad8fd72dc4134049d690b04e6 1206 PANTHER PTHR11365:SF2 1 1204 0.0 T 23-04-2016 DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 Pfam PF13620 Carboxypeptidase regulatory-like domain 632 705 5.7E-12 T 23-04-2016 DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 Pfam PF13620 Carboxypeptidase regulatory-like domain 723 799 4.1E-14 T 23-04-2016 DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 Pfam PF13620 Carboxypeptidase regulatory-like domain 547 625 2.7E-11 T 23-04-2016 DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 Gene3D G3DSA:1.20.1250.20 41 215 6.7E-27 T 23-04-2016 DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 PANTHER PTHR23501 556 574 2.1E-216 T 23-04-2016 DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 PANTHER PTHR23501 38 505 2.1E-216 T 23-04-2016 DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 Gene3D G3DSA:1.20.1250.20 286 489 2.5E-20 T 23-04-2016 DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 SUPERFAMILY SSF103473 15 222 4.97E-58 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 SUPERFAMILY SSF103473 270 487 4.97E-58 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 SUPERFAMILY SSF49452 627 706 2.35E-9 T 23-04-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 SUPERFAMILY SSF49464 723 800 3.49E-10 T 23-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 Pfam PF07690 Major Facilitator Superfamily 41 435 3.7E-40 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 Gene3D G3DSA:2.60.40.10 633 698 3.1E-8 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 Gene3D G3DSA:2.60.40.1120 723 801 1.9E-10 T 23-04-2016 IPR014766 Carboxypeptidase, regulatory domain DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 Gene3D G3DSA:2.60.40.1120 547 630 1.4E-11 T 23-04-2016 IPR014766 Carboxypeptidase, regulatory domain DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 SUPERFAMILY SSF49464 547 624 2.2E-11 T 23-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 PANTHER PTHR23501:SF15 556 574 2.1E-216 T 23-04-2016 DC74_RS35830 c71db0d33728ecbf76abe391d6b1a00f 808 PANTHER PTHR23501:SF15 38 505 2.1E-216 T 23-04-2016 DC74_RS17305 84de31da8e06261a1cb5ee90859f339d 276 PANTHER PTHR41282:SF1 11 276 2.8E-66 T 23-04-2016 DC74_RS17305 84de31da8e06261a1cb5ee90859f339d 276 PIRSF PIRSF009160 1 276 9.6E-85 T 23-04-2016 IPR010539 Protein of unknown function UCP009160 DC74_RS17305 84de31da8e06261a1cb5ee90859f339d 276 Pfam PF12811 Bax inhibitor 1 like 40 275 3.5E-81 T 23-04-2016 IPR010539 Protein of unknown function UCP009160 DC74_RS17305 84de31da8e06261a1cb5ee90859f339d 276 PANTHER PTHR41282 11 276 2.8E-66 T 23-04-2016 DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 67 3.5E-7 T 23-04-2016 IPR000014 PAS domain DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 Pfam PF08448 PAS fold 140 257 1.0E-17 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 SUPERFAMILY SSF55785 15 104 1.54E-13 T 23-04-2016 IPR000014 PAS domain DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 Pfam PF13581 Histidine kinase-like ATPase domain 680 788 4.0E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 SUPERFAMILY SSF81606 457 666 1.88E-6 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 Gene3D G3DSA:3.30.450.40 266 418 1.7E-16 T 23-04-2016 IPR029016 GAF domain-like DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 PANTHER PTHR21021 536 676 7.2E-47 T 23-04-2016 DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 PANTHER PTHR21021 402 519 7.2E-47 T 23-04-2016 DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 Pfam PF00989 PAS fold 20 66 4.2E-8 T 23-04-2016 IPR013767 PAS fold GO:0006355 DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 SMART SM00331 442 667 7.5E-28 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 PANTHER PTHR21021:SF19 536 676 7.2E-47 T 23-04-2016 DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 PANTHER PTHR21021:SF19 402 519 7.2E-47 T 23-04-2016 DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 Gene3D G3DSA:3.30.450.20 126 255 3.4E-14 T 23-04-2016 DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 Gene3D G3DSA:3.30.450.20 9 117 2.6E-11 T 23-04-2016 DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 SUPERFAMILY SSF55874 708 781 5.65E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 469 667 3.7E-49 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 SUPERFAMILY SSF55781 257 418 3.6E-6 T 23-04-2016 IPR029016 GAF domain-like DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 SMART SM00091 11 78 3.7E-8 T 23-04-2016 IPR000014 PAS domain DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 SMART SM00091 133 200 0.48 T 23-04-2016 IPR000014 PAS domain DC74_RS07195 ff9e356a8e92f8ef9e5aad27b4886156 805 SUPERFAMILY SSF55785 133 246 5.06E-11 T 23-04-2016 IPR000014 PAS domain DC74_RS36840 ab3781a68401bc1aec28cc06129e3fbc 329 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 276 318 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS36840 ab3781a68401bc1aec28cc06129e3fbc 329 SUPERFAMILY SSF52317 8 204 3.7E-48 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS36840 ab3781a68401bc1aec28cc06129e3fbc 329 SUPERFAMILY SSF46689 223 272 1.13E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS36840 ab3781a68401bc1aec28cc06129e3fbc 329 Pfam PF01965 DJ-1/PfpI family 8 184 2.6E-26 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS36840 ab3781a68401bc1aec28cc06129e3fbc 329 PANTHER PTHR11019:SF58 1 329 1.7E-85 T 23-04-2016 DC74_RS36840 ab3781a68401bc1aec28cc06129e3fbc 329 PANTHER PTHR11019 1 329 1.7E-85 T 23-04-2016 DC74_RS36840 ab3781a68401bc1aec28cc06129e3fbc 329 Gene3D G3DSA:1.10.10.60 278 326 2.0E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS36840 ab3781a68401bc1aec28cc06129e3fbc 329 SUPERFAMILY SSF46689 276 326 5.83E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS36840 ab3781a68401bc1aec28cc06129e3fbc 329 Pfam PF12833 Helix-turn-helix domain 245 324 1.1E-23 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS36840 ab3781a68401bc1aec28cc06129e3fbc 329 SMART SM00342 239 322 8.9E-27 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS36840 ab3781a68401bc1aec28cc06129e3fbc 329 Gene3D G3DSA:3.40.50.880 8 228 5.2E-55 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS36840 ab3781a68401bc1aec28cc06129e3fbc 329 Gene3D G3DSA:1.10.10.60 229 277 1.4E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39590 3892584a49e83ad08d5db0ee19ee15b7 153 Pfam PF01047 MarR family 32 90 1.7E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS39590 3892584a49e83ad08d5db0ee19ee15b7 153 PANTHER PTHR33164 1 149 1.6E-20 T 23-04-2016 DC74_RS39590 3892584a49e83ad08d5db0ee19ee15b7 153 SMART SM00347 24 128 3.3E-13 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS39590 3892584a49e83ad08d5db0ee19ee15b7 153 Gene3D G3DSA:1.10.10.10 3 138 9.8E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39590 3892584a49e83ad08d5db0ee19ee15b7 153 SUPERFAMILY SSF46785 5 138 8.93E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 Gene3D G3DSA:3.30.450.20 173 281 2.1E-6 T 23-04-2016 DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 SMART SM00387 382 486 4.2E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 Pfam PF07568 Histidine kinase 290 360 1.4E-22 T 23-04-2016 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 484 6.5E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 PANTHER PTHR24423:SF472 156 489 4.3E-169 T 23-04-2016 DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 PANTHER PTHR24423:SF472 1 125 4.3E-169 T 23-04-2016 DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 Pfam PF12282 Signal transduction histidine kinase 1 144 4.0E-60 T 23-04-2016 IPR022066 Signal transduction histidine kinase DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 Gene3D G3DSA:3.30.565.10 345 488 3.1E-17 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 SUPERFAMILY SSF55785 173 281 1.9E-6 T 23-04-2016 IPR000014 PAS domain DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 Pfam PF08448 PAS fold 172 276 4.0E-14 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 SUPERFAMILY SSF55874 351 484 9.95E-18 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 PANTHER PTHR24423 156 489 4.3E-169 T 23-04-2016 DC74_RS26470 f8ce3456a12858c66c480fa7f1417014 490 PANTHER PTHR24423 1 125 4.3E-169 T 23-04-2016 DC74_RS04665 a5986b9bf1d5c415f1f308445d86bc1c 184 Gene3D G3DSA:1.10.357.10 5 183 2.8E-32 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS04665 a5986b9bf1d5c415f1f308445d86bc1c 184 SUPERFAMILY SSF48498 81 182 1.19E-9 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS04665 a5986b9bf1d5c415f1f308445d86bc1c 184 SUPERFAMILY SSF46689 3 81 2.0E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04665 a5986b9bf1d5c415f1f308445d86bc1c 184 PANTHER PTHR30055 1 183 2.1E-34 T 23-04-2016 DC74_RS04665 a5986b9bf1d5c415f1f308445d86bc1c 184 PANTHER PTHR30055:SF19 1 183 2.1E-34 T 23-04-2016 DC74_RS04665 a5986b9bf1d5c415f1f308445d86bc1c 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 2.7E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS04805 b5989df6142c116a4c03f9e9ca01e035 277 Gene3D G3DSA:3.40.50.1820 5 271 3.4E-45 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS04805 b5989df6142c116a4c03f9e9ca01e035 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 4.0E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS04805 b5989df6142c116a4c03f9e9ca01e035 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 4.0E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS04805 b5989df6142c116a4c03f9e9ca01e035 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 214 228 4.0E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS04805 b5989df6142c116a4c03f9e9ca01e035 277 PANTHER PTHR10992 1 117 2.0E-31 T 23-04-2016 DC74_RS04805 b5989df6142c116a4c03f9e9ca01e035 277 PANTHER PTHR10992 155 271 2.0E-31 T 23-04-2016 DC74_RS04805 b5989df6142c116a4c03f9e9ca01e035 277 PRINTS PR00412 Epoxide hydrolase signature 54 69 3.3E-5 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS04805 b5989df6142c116a4c03f9e9ca01e035 277 PRINTS PR00412 Epoxide hydrolase signature 34 52 3.3E-5 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS04805 b5989df6142c116a4c03f9e9ca01e035 277 PRINTS PR00412 Epoxide hydrolase signature 246 268 3.3E-5 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS04805 b5989df6142c116a4c03f9e9ca01e035 277 SUPERFAMILY SSF53474 3 268 4.84E-46 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS04805 b5989df6142c116a4c03f9e9ca01e035 277 Pfam PF12146 Serine aminopeptidase, S33 30 249 1.6E-16 T 23-04-2016 IPR022742 Serine aminopeptidase, S33 DC74_RS03065 91b95048e6721f0d364db0c171f4ba45 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.7E-13 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS03065 91b95048e6721f0d364db0c171f4ba45 289 SUPERFAMILY SSF53850 87 287 2.79E-22 T 23-04-2016 DC74_RS03065 91b95048e6721f0d364db0c171f4ba45 289 Gene3D G3DSA:3.40.190.10 86 195 2.0E-12 T 23-04-2016 DC74_RS03065 91b95048e6721f0d364db0c171f4ba45 289 Pfam PF03466 LysR substrate binding domain 86 282 6.5E-24 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS03065 91b95048e6721f0d364db0c171f4ba45 289 SUPERFAMILY SSF46785 1 109 8.47E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03065 91b95048e6721f0d364db0c171f4ba45 289 Gene3D G3DSA:1.10.10.10 1 83 4.3E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03065 91b95048e6721f0d364db0c171f4ba45 289 Gene3D G3DSA:3.40.190.10 196 264 1.6E-12 T 23-04-2016 DC74_RS03065 91b95048e6721f0d364db0c171f4ba45 289 PANTHER PTHR30346 1 289 4.7E-52 T 23-04-2016 DC74_RS03065 91b95048e6721f0d364db0c171f4ba45 289 PANTHER PTHR30346:SF2 1 289 4.7E-52 T 23-04-2016 DC74_RS01615 80aaf128e5b7c01328b5a377a13962d9 365 Gene3D G3DSA:3.40.50.2300 231 351 1.2E-34 T 23-04-2016 DC74_RS01615 80aaf128e5b7c01328b5a377a13962d9 365 PANTHER PTHR26402:SF563 233 351 7.5E-42 T 23-04-2016 DC74_RS01615 80aaf128e5b7c01328b5a377a13962d9 365 SUPERFAMILY SSF57997 101 216 1.9E-5 T 23-04-2016 DC74_RS01615 80aaf128e5b7c01328b5a377a13962d9 365 Pfam PF00072 Response regulator receiver domain 235 348 9.6E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS01615 80aaf128e5b7c01328b5a377a13962d9 365 PANTHER PTHR26402 233 351 7.5E-42 T 23-04-2016 DC74_RS01615 80aaf128e5b7c01328b5a377a13962d9 365 SMART SM00448 233 348 7.7E-32 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS01615 80aaf128e5b7c01328b5a377a13962d9 365 SUPERFAMILY SSF52172 232 358 6.12E-35 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS30400 b8024af668b9915613e26a576b1052bb 276 Pfam PF03771 Domain of unknown function (DUF317) 59 115 5.2E-15 T 23-04-2016 IPR005523 Domain of unknown function DUF317 DC74_RS07445 2532f6352385d9b289e719be53718e3c 334 PANTHER PTHR11695 17 303 1.3E-13 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS07445 2532f6352385d9b289e719be53718e3c 334 Gene3D G3DSA:3.40.50.720 150 256 2.4E-12 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07445 2532f6352385d9b289e719be53718e3c 334 Gene3D G3DSA:3.90.180.10 12 149 1.6E-8 T 23-04-2016 IPR011032 GroES-like DC74_RS07445 2532f6352385d9b289e719be53718e3c 334 SUPERFAMILY SSF50129 5 155 1.45E-15 T 23-04-2016 IPR011032 GroES-like DC74_RS07445 2532f6352385d9b289e719be53718e3c 334 SUPERFAMILY SSF51735 121 263 3.95E-17 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37740 b1f48a4887d909467e436e5b177880ce 516 PANTHER PTHR23088:SF29 269 497 9.3E-18 T 23-04-2016 DC74_RS37740 b1f48a4887d909467e436e5b177880ce 516 PANTHER PTHR23088 269 497 9.3E-18 T 23-04-2016 DC74_RS37740 b1f48a4887d909467e436e5b177880ce 516 SUPERFAMILY SSF56317 270 481 4.84E-29 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS37740 b1f48a4887d909467e436e5b177880ce 516 Gene3D G3DSA:3.60.110.10 270 482 3.6E-24 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS37740 b1f48a4887d909467e436e5b177880ce 516 Pfam PF00795 Carbon-nitrogen hydrolase 275 462 4.6E-10 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS28185 f6e4ce8efd87fc872172b031744f5877 179 PANTHER PTHR30055:SF2 1 179 2.2E-38 T 23-04-2016 DC74_RS28185 f6e4ce8efd87fc872172b031744f5877 179 SUPERFAMILY SSF46689 3 69 6.48E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS28185 f6e4ce8efd87fc872172b031744f5877 179 PANTHER PTHR30055 1 179 2.2E-38 T 23-04-2016 DC74_RS28185 f6e4ce8efd87fc872172b031744f5877 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 52 5.5E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS28185 f6e4ce8efd87fc872172b031744f5877 179 SUPERFAMILY SSF48498 73 178 9.49E-7 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS28185 f6e4ce8efd87fc872172b031744f5877 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 50 2.7E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS28185 f6e4ce8efd87fc872172b031744f5877 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 6 19 2.7E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS28185 f6e4ce8efd87fc872172b031744f5877 179 Gene3D G3DSA:1.10.357.10 3 178 5.1E-26 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS27765 fa24e7d2402d8e022577b05dfe435526 346 Hamap MF_01841 Agmatine deiminase [aguA]. 2 345 48.951 T 23-04-2016 IPR017754 Agmatine deiminase GO:0009446|GO:0047632 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 DC74_RS27765 fa24e7d2402d8e022577b05dfe435526 346 PANTHER PTHR31377:SF0 1 344 1.2E-126 T 23-04-2016 DC74_RS27765 fa24e7d2402d8e022577b05dfe435526 346 Gene3D G3DSA:3.75.10.10 2 345 2.1E-121 T 23-04-2016 DC74_RS27765 fa24e7d2402d8e022577b05dfe435526 346 SUPERFAMILY SSF55909 3 345 1.68E-119 T 23-04-2016 DC74_RS27765 fa24e7d2402d8e022577b05dfe435526 346 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 10 344 2.0E-105 T 23-04-2016 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 DC74_RS27765 fa24e7d2402d8e022577b05dfe435526 346 PANTHER PTHR31377 1 344 1.2E-126 T 23-04-2016 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 Pfam PF03704 Bacterial transcriptional activator domain 110 254 2.7E-42 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 PANTHER PTHR22845 155 640 8.4E-186 T 23-04-2016 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 SMART SM00028 927 960 2.9 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 SMART SM00028 767 800 42.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 SMART SM00028 847 880 15.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 SMART SM00028 807 840 24.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 SMART SM00028 115 148 370.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 SMART SM00862 26 100 4.1E-7 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 Pfam PF13424 Tetratricopeptide repeat 771 837 3.7E-9 T 23-04-2016 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 PRINTS PR00364 Disease resistance protein signature 474 488 1.7E-8 T 23-04-2016 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 PRINTS PR00364 Disease resistance protein signature 389 403 1.7E-8 T 23-04-2016 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 PRINTS PR00364 Disease resistance protein signature 312 327 1.7E-8 T 23-04-2016 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 SUPERFAMILY SSF48452 769 956 5.87E-14 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 SMART SM01043 110 254 5.8E-49 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 Gene3D G3DSA:1.10.10.10 33 101 1.3E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 SUPERFAMILY SSF46894 13 99 2.52E-12 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 SUPERFAMILY SSF48452 107 275 7.59E-34 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 Pfam PF00486 Transcriptional regulatory protein, C terminal 33 90 8.2E-8 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 Pfam PF00931 NB-ARC domain 295 533 2.3E-14 T 23-04-2016 IPR002182 NB-ARC GO:0043531 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 SUPERFAMILY SSF52540 276 541 1.07E-26 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 Gene3D G3DSA:1.25.40.10 701 723 1.1E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 Gene3D G3DSA:1.25.40.10 108 227 1.1E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 Gene3D G3DSA:1.25.40.10 598 599 1.1E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 Gene3D G3DSA:1.25.40.10 724 960 3.5E-20 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 Gene3D G3DSA:3.40.50.300 311 405 3.0E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18220 cd0c216fcfb8c1e86aff218e492952a4 978 PANTHER PTHR22845:SF4 155 640 8.4E-186 T 23-04-2016 DC74_RS04350 9afcbb57197123386fc88ba5ccbb7be6 311 Gene3D G3DSA:3.30.1490.20 141 183 1.7E-6 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS04350 9afcbb57197123386fc88ba5ccbb7be6 311 Gene3D G3DSA:3.30.470.20 184 308 2.5E-39 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS04350 9afcbb57197123386fc88ba5ccbb7be6 311 Gene3D G3DSA:3.30.470.20 92 109 2.5E-39 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS04350 9afcbb57197123386fc88ba5ccbb7be6 311 PANTHER PTHR23132 59 309 1.0E-58 T 23-04-2016 DC74_RS04350 9afcbb57197123386fc88ba5ccbb7be6 311 Pfam PF07478 D-ala D-ala ligase C-terminus 142 306 2.3E-36 T 23-04-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS04350 9afcbb57197123386fc88ba5ccbb7be6 311 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 252 280 - T 23-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS04350 9afcbb57197123386fc88ba5ccbb7be6 311 Gene3D G3DSA:3.40.50.20 44 91 2.4E-10 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS04350 9afcbb57197123386fc88ba5ccbb7be6 311 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 69 80 - T 23-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS04350 9afcbb57197123386fc88ba5ccbb7be6 311 SUPERFAMILY SSF52440 38 101 2.4E-12 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS04350 9afcbb57197123386fc88ba5ccbb7be6 311 SUPERFAMILY SSF56059 103 306 1.04E-40 T 23-04-2016 DC74_RS04350 9afcbb57197123386fc88ba5ccbb7be6 311 Pfam PF01820 D-ala D-ala ligase N-terminus 36 92 1.9E-9 T 23-04-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS10120 8e6aa454e9a2076b451f095aeceb9ad4 255 Gene3D G3DSA:1.20.1080.10 5 225 3.1E-60 T 23-04-2016 IPR023271 Aquaporin-like DC74_RS10120 8e6aa454e9a2076b451f095aeceb9ad4 255 SUPERFAMILY SSF81338 7 228 2.88E-56 T 23-04-2016 IPR023271 Aquaporin-like DC74_RS10120 8e6aa454e9a2076b451f095aeceb9ad4 255 ProSitePatterns PS00221 MIP family signature. 61 69 - T 23-04-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 DC74_RS10120 8e6aa454e9a2076b451f095aeceb9ad4 255 TIGRFAM TIGR00861 MIP: MIP family channel proteins 11 222 2.2E-51 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10120 8e6aa454e9a2076b451f095aeceb9ad4 255 PRINTS PR00783 Major intrinsic protein family signature 80 99 6.6E-54 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10120 8e6aa454e9a2076b451f095aeceb9ad4 255 PRINTS PR00783 Major intrinsic protein family signature 43 67 6.6E-54 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10120 8e6aa454e9a2076b451f095aeceb9ad4 255 PRINTS PR00783 Major intrinsic protein family signature 205 225 6.6E-54 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10120 8e6aa454e9a2076b451f095aeceb9ad4 255 PRINTS PR00783 Major intrinsic protein family signature 166 188 6.6E-54 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10120 8e6aa454e9a2076b451f095aeceb9ad4 255 PRINTS PR00783 Major intrinsic protein family signature 136 154 6.6E-54 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10120 8e6aa454e9a2076b451f095aeceb9ad4 255 PRINTS PR00783 Major intrinsic protein family signature 7 26 6.6E-54 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10120 8e6aa454e9a2076b451f095aeceb9ad4 255 Pfam PF00230 Major intrinsic protein 4 222 6.7E-51 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10120 8e6aa454e9a2076b451f095aeceb9ad4 255 PANTHER PTHR19139 7 224 6.3E-64 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS39290 947cea8419b56f461491189e8d85345b 290 PANTHER PTHR23309 3 281 2.6E-107 T 23-04-2016 DC74_RS39290 947cea8419b56f461491189e8d85345b 290 SUPERFAMILY SSF48179 184 285 3.23E-30 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS39290 947cea8419b56f461491189e8d85345b 290 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 182 1.4E-54 T 23-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS39290 947cea8419b56f461491189e8d85345b 290 Gene3D G3DSA:3.40.50.720 2 186 1.2E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39290 947cea8419b56f461491189e8d85345b 290 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 185 281 6.0E-30 T 23-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS39290 947cea8419b56f461491189e8d85345b 290 PIRSF PIRSF000105 1 290 7.1E-83 T 23-04-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 DC74_RS39290 947cea8419b56f461491189e8d85345b 290 Gene3D G3DSA:1.10.1040.10 187 281 3.8E-28 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS39290 947cea8419b56f461491189e8d85345b 290 SUPERFAMILY SSF51735 2 184 7.09E-49 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38355 c49b9ac1c60dcba8e063d100072feb0a 338 Pfam PF13285 Domain of unknown function (DUF4073) 251 329 7.2E-11 T 23-04-2016 IPR025142 Domain of unknown function DUF4073 DC74_RS38355 c49b9ac1c60dcba8e063d100072feb0a 338 SUPERFAMILY SSF56300 37 323 2.81E-34 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS38355 c49b9ac1c60dcba8e063d100072feb0a 338 Gene3D G3DSA:3.60.21.10 36 330 1.2E-25 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS38355 c49b9ac1c60dcba8e063d100072feb0a 338 Pfam PF00149 Calcineurin-like phosphoesterase 39 250 1.7E-16 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 PANTHER PTHR23501 25 515 1.0E-93 T 23-04-2016 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 Gene3D G3DSA:1.20.1250.20 55 231 8.0E-23 T 23-04-2016 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 SUPERFAMILY SSF49464 577 654 1.45E-9 T 23-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 Gene3D G3DSA:2.60.40.10 746 799 2.3E-11 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 Gene3D G3DSA:1.20.1250.20 299 450 4.5E-6 T 23-04-2016 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 SUPERFAMILY SSF49452 654 738 2.75E-12 T 23-04-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 Gene3D G3DSA:2.60.40.1120 660 740 1.5E-12 T 23-04-2016 IPR014766 Carboxypeptidase, regulatory domain DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 Gene3D G3DSA:2.60.40.1120 578 654 1.2E-8 T 23-04-2016 IPR014766 Carboxypeptidase, regulatory domain DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 Pfam PF07690 Major Facilitator Superfamily 56 448 4.2E-28 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 PRINTS PR01035 Tetracycline resistance protein signature 61 77 8.6E-8 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 PRINTS PR01035 Tetracycline resistance protein signature 117 141 8.6E-8 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 PRINTS PR01035 Tetracycline resistance protein signature 175 197 8.6E-8 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 SUPERFAMILY SSF49478 744 811 4.32E-11 T 23-04-2016 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 Pfam PF13620 Carboxypeptidase regulatory-like domain 744 820 3.3E-12 T 23-04-2016 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 Pfam PF13620 Carboxypeptidase regulatory-like domain 579 654 1.7E-9 T 23-04-2016 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 Pfam PF13620 Carboxypeptidase regulatory-like domain 660 738 7.1E-15 T 23-04-2016 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 PANTHER PTHR23501:SF73 25 515 1.0E-93 T 23-04-2016 DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 SUPERFAMILY SSF103473 487 510 2.09E-39 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 SUPERFAMILY SSF103473 285 455 2.09E-39 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS31820 e4bc43d7d83db74e12b49ca7ef8a0a10 824 SUPERFAMILY SSF103473 32 233 2.09E-39 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS00490 35844f80bd16381296a762d0d286759c 366 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 19 348 1.6E-130 T 23-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 DC74_RS00490 35844f80bd16381296a762d0d286759c 366 PIRSF PIRSF005508 6 364 1.1E-138 T 23-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 DC74_RS00490 35844f80bd16381296a762d0d286759c 366 Pfam PF01758 Sodium Bile acid symporter family 64 261 4.4E-60 T 23-04-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 DC74_RS00490 35844f80bd16381296a762d0d286759c 366 PANTHER PTHR10361:SF31 5 365 2.7E-166 T 23-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 DC74_RS00490 35844f80bd16381296a762d0d286759c 366 PANTHER PTHR10361 5 365 2.7E-166 T 23-04-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 DC74_RS26715 1f9e6c42c7c97b0f64ed98861068cc76 286 SMART SM00641 81 190 2.9E-46 T 23-04-2016 IPR018077 Glycoside hydrolase, family 25 subgroup DC74_RS26715 1f9e6c42c7c97b0f64ed98861068cc76 286 PANTHER PTHR34135:SF2 79 275 1.5E-68 T 23-04-2016 DC74_RS26715 1f9e6c42c7c97b0f64ed98861068cc76 286 PANTHER PTHR34135 79 275 1.5E-68 T 23-04-2016 DC74_RS26715 1f9e6c42c7c97b0f64ed98861068cc76 286 Gene3D G3DSA:3.20.20.80 80 285 5.9E-69 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS26715 1f9e6c42c7c97b0f64ed98861068cc76 286 Pfam PF01183 Glycosyl hydrolases family 25 84 268 2.5E-49 T 23-04-2016 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 DC74_RS26715 1f9e6c42c7c97b0f64ed98861068cc76 286 SUPERFAMILY SSF51445 80 285 1.16E-61 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS26190 010eb94cea1361807b142b3352b46c13 81 Pfam PF00462 Glutaredoxin 5 60 3.2E-13 T 23-04-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 DC74_RS26190 010eb94cea1361807b142b3352b46c13 81 SUPERFAMILY SSF52833 4 74 1.81E-16 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS26190 010eb94cea1361807b142b3352b46c13 81 PANTHER PTHR34386 3 81 1.1E-18 T 23-04-2016 DC74_RS26190 010eb94cea1361807b142b3352b46c13 81 PANTHER PTHR34386:SF1 3 81 1.1E-18 T 23-04-2016 DC74_RS26190 010eb94cea1361807b142b3352b46c13 81 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 4 79 3.1E-33 T 23-04-2016 IPR011915 Glutaredoxin-like protein, actinobacteria DC74_RS26190 010eb94cea1361807b142b3352b46c13 81 Gene3D G3DSA:3.40.30.10 4 79 2.2E-20 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS07255 93a26a2bd5c97bbdae4741e7a1d89a38 483 ProSitePatterns PS00218 Amino acid permeases signature. 41 72 - T 23-04-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 DC74_RS07255 93a26a2bd5c97bbdae4741e7a1d89a38 483 Pfam PF13520 Amino acid permease 14 449 5.0E-59 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS07255 93a26a2bd5c97bbdae4741e7a1d89a38 483 PANTHER PTHR11785 1 469 4.4E-125 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS07255 93a26a2bd5c97bbdae4741e7a1d89a38 483 PIRSF PIRSF006060 1 481 1.3E-50 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS07255 93a26a2bd5c97bbdae4741e7a1d89a38 483 PANTHER PTHR11785:SF286 1 469 4.4E-125 T 23-04-2016 DC74_RS34340 832069f38afcdf1eb1f1225d5e6f3730 332 PANTHER PTHR23248 36 90 1.1E-26 T 23-04-2016 IPR005552 Scramblase DC74_RS34340 832069f38afcdf1eb1f1225d5e6f3730 332 PANTHER PTHR23248 109 321 1.1E-26 T 23-04-2016 IPR005552 Scramblase DC74_RS34340 832069f38afcdf1eb1f1225d5e6f3730 332 PANTHER PTHR23248:SF9 36 90 1.1E-26 T 23-04-2016 DC74_RS34340 832069f38afcdf1eb1f1225d5e6f3730 332 PANTHER PTHR23248:SF9 109 321 1.1E-26 T 23-04-2016 DC74_RS34340 832069f38afcdf1eb1f1225d5e6f3730 332 Pfam PF03803 Scramblase 140 322 3.5E-18 T 23-04-2016 IPR005552 Scramblase DC74_RS34340 832069f38afcdf1eb1f1225d5e6f3730 332 Pfam PF10708 Protein of unknown function (DUF2510) 8 42 5.3E-15 T 23-04-2016 IPR018929 Domain of unknown function DUF2510 DC74_RS34340 832069f38afcdf1eb1f1225d5e6f3730 332 SUPERFAMILY SSF54518 154 321 4.18E-9 T 23-04-2016 IPR025659 Tubby C-terminal-like domain DC74_RS31770 5f191dbd01cb13457a077a95bfd63104 659 Gene3D G3DSA:3.20.20.240 1 480 1.0E-182 T 23-04-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 DC74_RS31770 5f191dbd01cb13457a077a95bfd63104 659 SUPERFAMILY SSF52242 499 642 2.22E-44 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS31770 5f191dbd01cb13457a077a95bfd63104 659 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 1 485 1.4E-136 T 23-04-2016 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 DC74_RS31770 5f191dbd01cb13457a077a95bfd63104 659 SUPERFAMILY SSF51703 1 481 3.92E-158 T 23-04-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 DC74_RS31770 5f191dbd01cb13457a077a95bfd63104 659 Pfam PF02310 B12 binding domain 523 629 3.7E-18 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS31770 5f191dbd01cb13457a077a95bfd63104 659 PANTHER PTHR23408 1 626 0.0 T 23-04-2016 DC74_RS31770 5f191dbd01cb13457a077a95bfd63104 659 PANTHER PTHR23408:SF15 1 626 0.0 T 23-04-2016 DC74_RS31770 5f191dbd01cb13457a077a95bfd63104 659 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 520 648 1.1E-39 T 23-04-2016 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 DC74_RS31770 5f191dbd01cb13457a077a95bfd63104 659 Gene3D G3DSA:3.40.50.280 498 646 1.6E-49 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS31770 5f191dbd01cb13457a077a95bfd63104 659 Pfam PF01642 Methylmalonyl-CoA mutase 1 479 8.0E-128 T 23-04-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 Pfam PF01225 Mur ligase family, catalytic domain 32 94 1.2E-9 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 PANTHER PTHR23135:SF3 16 469 1.0E-160 T 23-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 Gene3D G3DSA:3.40.1390.10 3 81 1.1E-21 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 406 5.7E-19 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 34 464 7.3E-128 T 23-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 SUPERFAMILY SSF63418 3 98 1.44E-21 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 SUPERFAMILY SSF53623 103 313 1.02E-54 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 Gene3D G3DSA:3.40.1190.10 84 313 9.8E-72 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 Pfam PF08245 Mur ligase middle domain 108 297 3.4E-45 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 SUPERFAMILY SSF53244 320 464 8.01E-34 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 Gene3D G3DSA:3.90.190.20 319 465 3.0E-41 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 465 32.452 T 23-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS12560 f29fb4b426004df08855bb01beb957ca 480 PANTHER PTHR23135 16 469 1.0E-160 T 23-04-2016 DC74_RS09600 9a30f4bf784b41c7d6f312eb1639fa88 578 Pfam PF02355 Protein export membrane protein 365 541 6.4E-11 T 23-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial DC74_RS09600 9a30f4bf784b41c7d6f312eb1639fa88 578 PANTHER PTHR30081 256 570 9.9E-220 T 23-04-2016 DC74_RS09600 9a30f4bf784b41c7d6f312eb1639fa88 578 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 9 551 38.363 T 23-04-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 DC74_RS09600 9a30f4bf784b41c7d6f312eb1639fa88 578 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 290 528 1.4E-62 T 23-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial DC74_RS09600 9a30f4bf784b41c7d6f312eb1639fa88 578 PANTHER PTHR30081:SF4 16 129 9.9E-220 T 23-04-2016 DC74_RS09600 9a30f4bf784b41c7d6f312eb1639fa88 578 Gene3D G3DSA:1.20.1640.10 345 544 3.8E-22 T 23-04-2016 DC74_RS09600 9a30f4bf784b41c7d6f312eb1639fa88 578 PANTHER PTHR30081:SF4 256 570 9.9E-220 T 23-04-2016 DC74_RS09600 9a30f4bf784b41c7d6f312eb1639fa88 578 SUPERFAMILY SSF82866 342 543 2.49E-33 T 23-04-2016 DC74_RS09600 9a30f4bf784b41c7d6f312eb1639fa88 578 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 45 536 1.3E-106 T 23-04-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 DC74_RS09600 9a30f4bf784b41c7d6f312eb1639fa88 578 PANTHER PTHR30081 16 129 9.9E-220 T 23-04-2016 DC74_RS35400 b38409b87aa895d22b911a57da078d70 383 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 232 321 3.9E-14 T 23-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 DC74_RS35400 b38409b87aa895d22b911a57da078d70 383 PIRSF PIRSF001619 3 329 3.8E-105 T 23-04-2016 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 DC74_RS35400 b38409b87aa895d22b911a57da078d70 383 PANTHER PTHR22976:SF1 1 356 1.4E-143 T 23-04-2016 DC74_RS35400 b38409b87aa895d22b911a57da078d70 383 Pfam PF04055 Radical SAM superfamily 65 220 1.3E-11 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS35400 b38409b87aa895d22b911a57da078d70 383 SUPERFAMILY SSF102114 18 321 2.75E-74 T 23-04-2016 DC74_RS35400 b38409b87aa895d22b911a57da078d70 383 Gene3D G3DSA:3.20.20.70 17 322 3.7E-86 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS35400 b38409b87aa895d22b911a57da078d70 383 TIGRFAM TIGR00433 bioB: biotin synthase 28 321 5.5E-113 T 23-04-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 DC74_RS35400 b38409b87aa895d22b911a57da078d70 383 PANTHER PTHR22976 1 356 1.4E-143 T 23-04-2016 DC74_RS35400 b38409b87aa895d22b911a57da078d70 383 SMART SM00729 55 261 4.4E-36 T 23-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 DC74_RS35400 b38409b87aa895d22b911a57da078d70 383 SMART SM00876 232 322 9.3E-33 T 23-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 DC74_RS35400 b38409b87aa895d22b911a57da078d70 383 Hamap MF_01694 Biotin synthase [bioB]. 15 323 39.361 T 23-04-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 DC74_RS02510 0a044435116cc4d0320424819c452ec6 287 Pfam PF13714 Phosphoenolpyruvate phosphomutase 15 245 1.6E-33 T 23-04-2016 DC74_RS02510 0a044435116cc4d0320424819c452ec6 287 SUPERFAMILY SSF51621 5 267 1.61E-59 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS02510 0a044435116cc4d0320424819c452ec6 287 PANTHER PTHR21631:SF4 6 248 2.1E-39 T 23-04-2016 DC74_RS02510 0a044435116cc4d0320424819c452ec6 287 Gene3D G3DSA:3.20.20.60 5 255 9.5E-56 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS02510 0a044435116cc4d0320424819c452ec6 287 PANTHER PTHR21631 6 248 2.1E-39 T 23-04-2016 DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 PANTHER PTHR10992:SF878 393 508 1.5E-64 T 23-04-2016 DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 PANTHER PTHR10992:SF878 52 158 1.5E-64 T 23-04-2016 DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 Gene3D G3DSA:3.40.50.1820 204 330 2.8E-55 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 Gene3D G3DSA:3.40.50.1820 71 159 2.8E-55 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 Gene3D G3DSA:3.40.50.1820 386 506 2.8E-55 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 SUPERFAMILY SSF53474 339 487 7.94E-23 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 SUPERFAMILY SSF53474 99 160 7.94E-23 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 SUPERFAMILY SSF53474 206 260 7.94E-23 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 Pfam PF00561 alpha/beta hydrolase fold 107 486 3.6E-29 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 PANTHER PTHR10992 206 295 1.5E-64 T 23-04-2016 DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 PANTHER PTHR10992:SF878 206 295 1.5E-64 T 23-04-2016 DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 PANTHER PTHR10992 393 508 1.5E-64 T 23-04-2016 DC74_RS35655 a0777c6f5a957ff9af431659949955db 535 PANTHER PTHR10992 52 158 1.5E-64 T 23-04-2016 DC74_RS20350 82731ff3fe61bd892e42940acc323b1e 327 Gene3D G3DSA:3.40.50.970 5 196 9.4E-74 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS20350 82731ff3fe61bd892e42940acc323b1e 327 Pfam PF02779 Transketolase, pyrimidine binding domain 6 181 1.1E-46 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain DC74_RS20350 82731ff3fe61bd892e42940acc323b1e 327 PANTHER PTHR11624:SF79 5 327 2.3E-194 T 23-04-2016 DC74_RS20350 82731ff3fe61bd892e42940acc323b1e 327 SUPERFAMILY SSF52922 193 325 2.49E-39 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS20350 82731ff3fe61bd892e42940acc323b1e 327 Gene3D G3DSA:3.40.50.920 199 321 2.0E-43 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS20350 82731ff3fe61bd892e42940acc323b1e 327 PANTHER PTHR11624 5 327 2.3E-194 T 23-04-2016 IPR033247 Transketolase family DC74_RS20350 82731ff3fe61bd892e42940acc323b1e 327 SUPERFAMILY SSF52518 6 184 3.34E-66 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS20350 82731ff3fe61bd892e42940acc323b1e 327 SMART SM00861 7 182 2.7E-67 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain DC74_RS20350 82731ff3fe61bd892e42940acc323b1e 327 Pfam PF02780 Transketolase, C-terminal domain 197 316 3.0E-39 T 23-04-2016 IPR033248 Transketolase, C-terminal domain DC74_RS21685 36d38949c77f23baf6b84dd53f9df449 418 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 213 6.2E-58 T 23-04-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain DC74_RS21685 36d38949c77f23baf6b84dd53f9df449 418 PANTHER PTHR13748:SF4 2 324 1.9E-171 T 23-04-2016 DC74_RS21685 36d38949c77f23baf6b84dd53f9df449 418 PANTHER PTHR13748 349 384 1.9E-171 T 23-04-2016 DC74_RS21685 36d38949c77f23baf6b84dd53f9df449 418 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 259 372 1.0E-21 T 23-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal DC74_RS21685 36d38949c77f23baf6b84dd53f9df449 418 SMART SM00833 259 372 1.7E-30 T 23-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal DC74_RS21685 36d38949c77f23baf6b84dd53f9df449 418 Gene3D G3DSA:3.40.50.300 6 232 7.6E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21685 36d38949c77f23baf6b84dd53f9df449 418 SUPERFAMILY SSF52540 5 314 8.06E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21685 36d38949c77f23baf6b84dd53f9df449 418 PANTHER PTHR13748 2 324 1.9E-171 T 23-04-2016 DC74_RS21685 36d38949c77f23baf6b84dd53f9df449 418 PANTHER PTHR13748:SF4 349 384 1.9E-171 T 23-04-2016 DC74_RS21685 36d38949c77f23baf6b84dd53f9df449 418 Gene3D G3DSA:3.30.1220.10 247 372 1.8E-12 T 23-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 PANTHER PTHR19211 1 523 2.3E-255 T 23-04-2016 DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 ProSitePatterns PS00211 ABC transporters family signature. 437 451 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 PANTHER PTHR19211:SF53 1 523 2.3E-255 T 23-04-2016 DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 SUPERFAMILY SSF52540 324 507 4.69E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 Gene3D G3DSA:3.40.50.300 324 507 7.4E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 Gene3D G3DSA:3.40.50.300 4 94 1.0E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 Gene3D G3DSA:3.40.50.300 128 268 1.0E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 Pfam PF00005 ABC transporter 335 465 2.3E-21 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 Pfam PF00005 ABC transporter 9 181 6.0E-22 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 SMART SM00382 18 226 1.4E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 SMART SM00382 344 511 1.5E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 Pfam PF12848 ABC transporter 225 303 1.6E-6 T 23-04-2016 IPR032781 ABC-transporter extension domain DC74_RS02615 15cc2abad55e6401686d8390153999dc 526 SUPERFAMILY SSF52540 4 224 4.57E-37 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17785 7da545404068737ab59256679f543f1f 441 Gene3D G3DSA:1.10.287.130 189 243 2.8E-10 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS17785 7da545404068737ab59256679f543f1f 441 SUPERFAMILY SSF55874 322 427 3.67E-18 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17785 7da545404068737ab59256679f543f1f 441 Pfam PF00672 HAMP domain 127 193 6.8E-14 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS17785 7da545404068737ab59256679f543f1f 441 PANTHER PTHR24423:SF427 306 426 1.2E-32 T 23-04-2016 DC74_RS17785 7da545404068737ab59256679f543f1f 441 PANTHER PTHR24423:SF427 140 282 1.2E-32 T 23-04-2016 DC74_RS17785 7da545404068737ab59256679f543f1f 441 SMART SM00387 327 430 2.0E-17 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17785 7da545404068737ab59256679f543f1f 441 SUPERFAMILY SSF47384 182 256 8.83E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS17785 7da545404068737ab59256679f543f1f 441 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 327 424 2.2E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17785 7da545404068737ab59256679f543f1f 441 Pfam PF00512 His Kinase A (phospho-acceptor) domain 201 256 5.7E-8 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS17785 7da545404068737ab59256679f543f1f 441 SMART SM00304 146 198 9.6E-11 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS17785 7da545404068737ab59256679f543f1f 441 SMART SM00388 199 257 1.3E-9 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS17785 7da545404068737ab59256679f543f1f 441 PANTHER PTHR24423 306 426 1.2E-32 T 23-04-2016 DC74_RS17785 7da545404068737ab59256679f543f1f 441 PANTHER PTHR24423 140 282 1.2E-32 T 23-04-2016 DC74_RS17785 7da545404068737ab59256679f543f1f 441 SUPERFAMILY SSF158472 148 194 2.22E-8 T 23-04-2016 DC74_RS17785 7da545404068737ab59256679f543f1f 441 Gene3D G3DSA:3.30.565.10 244 426 5.9E-20 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23900 7b010820faeab04aecadd3cf3b60c888 211 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 4 211 40.098 T 23-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS23900 7b010820faeab04aecadd3cf3b60c888 211 Gene3D G3DSA:2.30.110.10 11 211 1.4E-86 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS23900 7b010820faeab04aecadd3cf3b60c888 211 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 2 211 7.4E-82 T 23-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS23900 7b010820faeab04aecadd3cf3b60c888 211 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 177 190 - T 23-04-2016 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS23900 7b010820faeab04aecadd3cf3b60c888 211 PANTHER PTHR10851 1 211 1.4E-103 T 23-04-2016 DC74_RS23900 7b010820faeab04aecadd3cf3b60c888 211 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 28 113 2.4E-26 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS23900 7b010820faeab04aecadd3cf3b60c888 211 PIRSF PIRSF000190 1 211 5.7E-82 T 23-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS23900 7b010820faeab04aecadd3cf3b60c888 211 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 167 211 6.3E-19 T 23-04-2016 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS23900 7b010820faeab04aecadd3cf3b60c888 211 SUPERFAMILY SSF50475 8 211 7.0E-69 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS23900 7b010820faeab04aecadd3cf3b60c888 211 PANTHER PTHR10851:SF0 1 211 1.4E-103 T 23-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS11245 03c2c79fea7185d86bfd5834f5051bf9 270 SMART SM00382 35 228 6.3E-8 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS11245 03c2c79fea7185d86bfd5834f5051bf9 270 PANTHER PTHR24220:SF383 12 245 3.0E-108 T 23-04-2016 DC74_RS11245 03c2c79fea7185d86bfd5834f5051bf9 270 Gene3D G3DSA:3.40.50.300 12 236 2.7E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11245 03c2c79fea7185d86bfd5834f5051bf9 270 Pfam PF00005 ABC transporter 27 177 6.2E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS11245 03c2c79fea7185d86bfd5834f5051bf9 270 PANTHER PTHR24220 12 245 3.0E-108 T 23-04-2016 DC74_RS11245 03c2c79fea7185d86bfd5834f5051bf9 270 SUPERFAMILY SSF52540 10 236 3.79E-48 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33755 a7047cfa47c487cdd831ed743dee93ec 394 Gene3D G3DSA:1.10.540.10 25 108 4.0E-18 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS33755 a7047cfa47c487cdd831ed743dee93ec 394 Gene3D G3DSA:2.40.110.10 110 207 3.1E-32 T 23-04-2016 DC74_RS33755 a7047cfa47c487cdd831ed743dee93ec 394 PANTHER PTHR10909 3 394 7.5E-155 T 23-04-2016 DC74_RS33755 a7047cfa47c487cdd831ed743dee93ec 394 Gene3D G3DSA:1.20.140.10 208 385 9.1E-25 T 23-04-2016 DC74_RS33755 a7047cfa47c487cdd831ed743dee93ec 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 28 107 1.2E-11 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS33755 a7047cfa47c487cdd831ed743dee93ec 394 SUPERFAMILY SSF56645 21 231 8.25E-63 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS33755 a7047cfa47c487cdd831ed743dee93ec 394 PANTHER PTHR10909:SF242 3 394 7.5E-155 T 23-04-2016 DC74_RS33755 a7047cfa47c487cdd831ed743dee93ec 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 111 195 1.1E-20 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS33755 a7047cfa47c487cdd831ed743dee93ec 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 218 375 1.4E-15 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS33755 a7047cfa47c487cdd831ed743dee93ec 394 SUPERFAMILY SSF47203 218 377 1.05E-14 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS31530 b5718a293683ed0ef2c19cc7fc949df5 212 PANTHER PTHR15032 1 182 4.3E-60 T 23-04-2016 DC74_RS31530 b5718a293683ed0ef2c19cc7fc949df5 212 PANTHER PTHR15032:SF14 1 182 4.3E-60 T 23-04-2016 DC74_RS31530 b5718a293683ed0ef2c19cc7fc949df5 212 Pfam PF13483 Beta-lactamase superfamily domain 2 176 1.2E-21 T 23-04-2016 DC74_RS31530 b5718a293683ed0ef2c19cc7fc949df5 212 SUPERFAMILY SSF56281 87 190 4.98E-17 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS31530 b5718a293683ed0ef2c19cc7fc949df5 212 SUPERFAMILY SSF56281 1 60 4.98E-17 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS31530 b5718a293683ed0ef2c19cc7fc949df5 212 Gene3D G3DSA:3.60.15.10 1 177 6.9E-24 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS31530 b5718a293683ed0ef2c19cc7fc949df5 212 SMART SM00849 7 176 9.3E-4 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS31070 f33fcd039a0d6af5fedc6b12c657cfb8 474 Gene3D G3DSA:3.40.640.10 102 349 3.5E-84 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS31070 f33fcd039a0d6af5fedc6b12c657cfb8 474 Pfam PF00266 Aminotransferase class-V 91 460 1.2E-133 T 23-04-2016 IPR000192 Aminotransferase class V domain DC74_RS31070 f33fcd039a0d6af5fedc6b12c657cfb8 474 PANTHER PTHR11601:SF17 75 466 1.6E-174 T 23-04-2016 DC74_RS31070 f33fcd039a0d6af5fedc6b12c657cfb8 474 SUPERFAMILY SSF53383 71 467 1.33E-119 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS31070 f33fcd039a0d6af5fedc6b12c657cfb8 474 PANTHER PTHR11601 75 466 1.6E-174 T 23-04-2016 DC74_RS31070 f33fcd039a0d6af5fedc6b12c657cfb8 474 Gene3D G3DSA:3.90.1150.10 350 466 6.4E-25 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS31070 f33fcd039a0d6af5fedc6b12c657cfb8 474 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 75 469 3.0E-156 T 23-04-2016 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 DC74_RS26045 fd543a9996a7f65a3d313fdbdc133b27 284 SUPERFAMILY SSF89550 2 80 4.51E-43 T 23-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 DC74_RS26045 fd543a9996a7f65a3d313fdbdc133b27 284 SUPERFAMILY SSF89550 163 255 4.51E-43 T 23-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 DC74_RS26045 fd543a9996a7f65a3d313fdbdc133b27 284 SMART SM00481 3 67 1.9E-15 T 23-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 DC74_RS26045 fd543a9996a7f65a3d313fdbdc133b27 284 PANTHER PTHR30007 1 259 5.6E-70 T 23-04-2016 DC74_RS26045 fd543a9996a7f65a3d313fdbdc133b27 284 Pfam PF02811 PHP domain 4 129 3.4E-8 T 23-04-2016 IPR004013 PHP domain GO:0003824 DC74_RS26045 fd543a9996a7f65a3d313fdbdc133b27 284 Gene3D G3DSA:3.20.20.140 155 254 3.9E-36 T 23-04-2016 DC74_RS26045 fd543a9996a7f65a3d313fdbdc133b27 284 Gene3D G3DSA:3.20.20.140 2 85 3.9E-36 T 23-04-2016 DC74_RS26045 fd543a9996a7f65a3d313fdbdc133b27 284 PANTHER PTHR30007:SF4 1 259 5.6E-70 T 23-04-2016 DC74_RS34385 9340e5b2579d7b1db80d5191bb670375 210 PANTHER PTHR26402:SF151 104 210 3.4E-18 T 23-04-2016 DC74_RS34385 9340e5b2579d7b1db80d5191bb670375 210 Gene3D G3DSA:1.10.10.10 106 209 1.9E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34385 9340e5b2579d7b1db80d5191bb670375 210 SUPERFAMILY SSF46894 136 209 2.82E-19 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS34385 9340e5b2579d7b1db80d5191bb670375 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 2.3E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34385 9340e5b2579d7b1db80d5191bb670375 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 2.3E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34385 9340e5b2579d7b1db80d5191bb670375 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 2.3E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34385 9340e5b2579d7b1db80d5191bb670375 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 1.1E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34385 9340e5b2579d7b1db80d5191bb670375 210 SMART SM00421 147 204 5.8E-21 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34385 9340e5b2579d7b1db80d5191bb670375 210 PANTHER PTHR26402 104 210 3.4E-18 T 23-04-2016 DC74_RS34385 9340e5b2579d7b1db80d5191bb670375 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37735 23a8b9415eb770838dff9b9955ee46f5 423 PANTHER PTHR24421 207 422 8.2E-73 T 23-04-2016 DC74_RS37735 23a8b9415eb770838dff9b9955ee46f5 423 PANTHER PTHR24421 53 188 8.2E-73 T 23-04-2016 DC74_RS37735 23a8b9415eb770838dff9b9955ee46f5 423 SUPERFAMILY SSF55874 324 420 3.72E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS37735 23a8b9415eb770838dff9b9955ee46f5 423 Pfam PF07730 Histidine kinase 212 275 1.5E-15 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS37735 23a8b9415eb770838dff9b9955ee46f5 423 PANTHER PTHR24421:SF26 207 422 8.2E-73 T 23-04-2016 DC74_RS37735 23a8b9415eb770838dff9b9955ee46f5 423 PANTHER PTHR24421:SF26 53 188 8.2E-73 T 23-04-2016 DC74_RS31845 ddbba0a4a6b3193598e143b253878404 277 Gene3D G3DSA:3.30.1360.130 217 268 3.5E-8 T 23-04-2016 DC74_RS31845 ddbba0a4a6b3193598e143b253878404 277 Pfam PF04951 D-aminopeptidase 2 262 5.2E-89 T 23-04-2016 IPR007035 Peptidase M55, D-aminopeptidase DC74_RS31845 ddbba0a4a6b3193598e143b253878404 277 Gene3D G3DSA:3.40.50.10780 2 204 5.2E-72 T 23-04-2016 IPR027476 D-aminopeptidase, N-terminal DC74_RS31845 ddbba0a4a6b3193598e143b253878404 277 PIRSF PIRSF015853 1 274 9.9E-91 T 23-04-2016 IPR007035 Peptidase M55, D-aminopeptidase DC74_RS31845 ddbba0a4a6b3193598e143b253878404 277 SUPERFAMILY SSF63992 2 267 1.16E-78 T 23-04-2016 IPR007035 Peptidase M55, D-aminopeptidase DC74_RS16635 354cab6711e118be0cfd2995383abcba 257 Gene3D G3DSA:3.40.50.150 90 251 9.9E-19 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS16635 354cab6711e118be0cfd2995383abcba 257 Pfam PF08242 Methyltransferase domain 97 198 7.2E-14 T 23-04-2016 IPR013217 Methyltransferase type 12 DC74_RS16635 354cab6711e118be0cfd2995383abcba 257 SUPERFAMILY SSF53335 84 245 6.78E-22 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS19910 4608770b95547735e1e3fbef567ca23f 392 Gene3D G3DSA:3.40.640.10 43 259 4.6E-73 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS19910 4608770b95547735e1e3fbef567ca23f 392 PANTHER PTHR11751 4 392 2.2E-140 T 23-04-2016 DC74_RS19910 4608770b95547735e1e3fbef567ca23f 392 Gene3D G3DSA:3.90.1150.10 260 392 1.1E-26 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS19910 4608770b95547735e1e3fbef567ca23f 392 PANTHER PTHR11751:SF428 4 392 2.2E-140 T 23-04-2016 DC74_RS19910 4608770b95547735e1e3fbef567ca23f 392 Pfam PF00155 Aminotransferase class I and II 31 388 1.8E-64 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS19910 4608770b95547735e1e3fbef567ca23f 392 SUPERFAMILY SSF53383 4 391 2.26E-106 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 Gene3D G3DSA:1.10.580.10 52 281 9.7E-95 T 23-04-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 PRINTS PR00143 Citrate synthase signature 297 317 2.7E-54 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 PRINTS PR00143 Citrate synthase signature 380 394 2.7E-54 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 PRINTS PR00143 Citrate synthase signature 219 234 2.7E-54 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 PRINTS PR00143 Citrate synthase signature 165 178 2.7E-54 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 PRINTS PR00143 Citrate synthase signature 241 269 2.7E-54 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 PRINTS PR00143 Citrate synthase signature 360 376 2.7E-54 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 14 423 1.2E-182 T 23-04-2016 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 UniPathway: UPA00223 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 ProSitePatterns PS00480 Citrate synthase signature. 304 316 - T 23-04-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 SUPERFAMILY SSF48256 3 429 1.57E-159 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 PIRSF PIRSF001369 37 429 7.8E-155 T 23-04-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 Pfam PF00285 Citrate synthase, C-terminal domain 46 412 2.3E-134 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 PANTHER PTHR11739 19 429 4.7E-196 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS15765 cffae4f7dcac34623f5c0605a4303ad5 429 Gene3D G3DSA:1.10.230.10 282 374 4.0E-36 T 23-04-2016 IPR016143 Citrate synthase-like, small alpha subdomain DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 SUPERFAMILY SSF47781 579 689 1.43E-24 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 SUPERFAMILY SSF82771 17 101 3.92E-23 T 23-04-2016 IPR000305 GIY-YIG nuclease superfamily DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 Gene3D G3DSA:3.40.1440.10 18 95 9.6E-10 T 23-04-2016 IPR027299 GIY-YIG domain DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 SMART SM00278 636 655 7.2 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 SMART SM00278 668 687 0.12 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 Pfam PF02151 UvrB/uvrC motif 211 242 2.7E-9 T 23-04-2016 IPR001943 UVR domain GO:0005515 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 Pfam PF01541 GIY-YIG catalytic domain 19 92 8.1E-11 T 23-04-2016 IPR000305 GIY-YIG nuclease superfamily DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 Gene3D G3DSA:1.10.150.20 636 688 3.0E-22 T 23-04-2016 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 393 621 8.5E-50 T 23-04-2016 IPR001162 UvrC family homology region DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 PANTHER PTHR30562:SF1 548 688 1.5E-267 T 23-04-2016 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 PANTHER PTHR30562:SF1 1 475 1.5E-267 T 23-04-2016 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 SUPERFAMILY SSF46600 194 246 9.29E-13 T 23-04-2016 IPR001943 UVR domain GO:0005515 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 SMART SM00465 17 99 1.4E-20 T 23-04-2016 IPR000305 GIY-YIG nuclease superfamily DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 11 477 2.7E-126 T 23-04-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 687 30.326 T 23-04-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 Gene3D G3DSA:4.10.860.10 187 246 2.1E-18 T 23-04-2016 IPR001943 UVR domain GO:0005515 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 Pfam PF14520 Helix-hairpin-helix domain 638 688 3.1E-10 T 23-04-2016 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 PANTHER PTHR30562 548 688 1.5E-267 T 23-04-2016 DC74_RS11850 0b93649b4cfc2842ecf2794579ee30fa 724 PANTHER PTHR30562 1 475 1.5E-267 T 23-04-2016 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF51735 976 1184 1.18E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 PANTHER PTHR11712 2994 3003 0.0 T 23-04-2016 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 PANTHER PTHR11712 1198 2572 0.0 T 23-04-2016 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 570 868 1.8E-120 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2118 2419 3.7E-128 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF47336 1480 1591 1.96E-19 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:3.30.70.250 693 758 8.0E-10 T 23-04-2016 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:3.30.70.250 2241 2305 5.9E-9 T 23-04-2016 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Pfam PF00550 Phosphopantetheine attachment site 1486 1551 1.5E-8 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF53901 1575 1949 1.56E-104 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Pfam PF08990 Erythronolide synthase docking 12 35 1.8E-8 T 23-04-2016 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF55048 694 759 2.35E-14 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF51735 2750 2984 2.5E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Pfam PF08659 KR domain 2751 2929 6.3E-58 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Pfam PF08659 KR domain 1198 1376 1.0E-53 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 200 216 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1740 1756 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF51735 1194 1438 2.43E-42 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:3.40.50.720 2751 2934 5.9E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:3.40.50.720 1198 1380 2.6E-32 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SMART SM00823 Phosphopantetheine attachment site 1483 1555 4.9E-25 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:3.40.47.10 300 465 1.9E-63 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:3.40.47.10 1840 2006 2.1E-64 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF52151 566 695 4.45E-66 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF52151 760 860 4.45E-66 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1835 1952 1.1E-43 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 295 412 1.1E-42 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:3.40.47.10 1574 1839 3.5E-93 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:3.40.47.10 37 299 8.8E-86 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF55048 2241 2306 1.7E-14 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 PANTHER PTHR11712:SF242 2994 3003 0.0 T 23-04-2016 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 PANTHER PTHR11712:SF242 1198 2572 0.0 T 23-04-2016 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF53901 39 410 1.41E-98 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 415 530 1.6E-13 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1955 2080 2.0E-12 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SMART SM00825 Beta-ketoacyl synthase 44 465 8.8E-206 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SMART SM00825 Beta-ketoacyl synthase 1579 2005 8.2E-223 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF51735 2532 2737 4.33E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1510 1525 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:3.40.366.10 2115 2237 9.4E-76 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:3.40.366.10 2306 2421 9.4E-76 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:3.40.366.10 759 870 4.3E-71 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:3.40.366.10 564 689 4.3E-71 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF52151 2116 2243 2.54E-70 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SUPERFAMILY SSF52151 2307 2401 2.54E-70 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SMART SM01294 1484 1551 2.5E-4 T 23-04-2016 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Pfam PF00698 Acyl transferase domain 568 887 7.5E-83 T 23-04-2016 IPR014043 Acyl transferase DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Pfam PF00698 Acyl transferase domain 2116 2437 3.2E-91 T 23-04-2016 IPR014043 Acyl transferase DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2751 2931 4.0E-50 T 23-04-2016 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1198 1378 1.1E-40 T 23-04-2016 DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Gene3D G3DSA:1.10.1200.10 1481 1553 1.2E-18 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 42 287 1.8E-79 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS38750 ec34eff874c65dfbe2278508706f143a 3199 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1577 1827 1.5E-91 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS32320 991e6715a6b708bea1e8763080465342 497 SUPERFAMILY SSF51905 266 379 1.11E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS32320 991e6715a6b708bea1e8763080465342 497 SUPERFAMILY SSF51905 8 169 1.11E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS32320 991e6715a6b708bea1e8763080465342 497 Gene3D G3DSA:3.50.50.60 258 335 2.2E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS32320 991e6715a6b708bea1e8763080465342 497 Gene3D G3DSA:3.50.50.60 7 174 2.2E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS32320 991e6715a6b708bea1e8763080465342 497 PANTHER PTHR13789:SF90 7 343 6.4E-73 T 23-04-2016 DC74_RS32320 991e6715a6b708bea1e8763080465342 497 PANTHER PTHR13789 7 343 6.4E-73 T 23-04-2016 DC74_RS32320 991e6715a6b708bea1e8763080465342 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 321 1.3E-39 T 23-04-2016 DC74_RS32320 991e6715a6b708bea1e8763080465342 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 337 1.3E-39 T 23-04-2016 DC74_RS32320 991e6715a6b708bea1e8763080465342 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 1.3E-39 T 23-04-2016 DC74_RS32320 991e6715a6b708bea1e8763080465342 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.3E-39 T 23-04-2016 DC74_RS32320 991e6715a6b708bea1e8763080465342 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 1.3E-39 T 23-04-2016 DC74_RS32320 991e6715a6b708bea1e8763080465342 497 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 301 1.3E-39 T 23-04-2016 DC74_RS32320 991e6715a6b708bea1e8763080465342 497 Pfam PF01494 FAD binding domain 7 333 1.1E-76 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS19535 ee0d3a72b2910e522bbc12058c6dd90c 588 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 268 450 1.7E-47 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS19535 ee0d3a72b2910e522bbc12058c6dd90c 588 Pfam PF13581 Histidine kinase-like ATPase domain 475 566 1.1E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS19535 ee0d3a72b2910e522bbc12058c6dd90c 588 SUPERFAMILY SSF55874 500 583 2.75E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS19535 ee0d3a72b2910e522bbc12058c6dd90c 588 SUPERFAMILY SSF81606 254 450 8.37E-7 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS19535 ee0d3a72b2910e522bbc12058c6dd90c 588 Gene3D G3DSA:3.30.450.20 80 204 4.6E-5 T 23-04-2016 DC74_RS19535 ee0d3a72b2910e522bbc12058c6dd90c 588 PANTHER PTHR21021:SF19 200 460 4.0E-51 T 23-04-2016 DC74_RS19535 ee0d3a72b2910e522bbc12058c6dd90c 588 PANTHER PTHR21021 200 460 4.0E-51 T 23-04-2016 DC74_RS19535 ee0d3a72b2910e522bbc12058c6dd90c 588 Pfam PF08448 PAS fold 85 173 1.3E-5 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS19535 ee0d3a72b2910e522bbc12058c6dd90c 588 SMART SM00331 238 451 1.4E-34 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 SUPERFAMILY SSF47336 552 662 4.06E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Pfam PF00501 AMP-binding enzyme 18 445 1.8E-81 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Gene3D G3DSA:3.30.70.250 1331 1394 2.1E-10 T 23-04-2016 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Gene3D G3DSA:3.30.300.30 441 538 4.6E-25 T 23-04-2016 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1201 1556 3.8E-106 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 SMART SM00823 Phosphopantetheine attachment site 557 628 2.7E-18 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 SUPERFAMILY SSF55048 1331 1394 2.62E-13 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 SUPERFAMILY SSF56801 9 540 2.22E-128 T 23-04-2016 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Pfam PF00550 Phosphopantetheine attachment site 560 624 3.3E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 906 1022 4.6E-45 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1025 1162 2.0E-13 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Gene3D G3DSA:3.40.366.10 1192 1326 2.9E-69 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Gene3D G3DSA:3.40.366.10 1395 1490 2.9E-69 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Gene3D G3DSA:1.10.1200.10 554 629 5.6E-18 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 SMART SM01294 558 624 0.0037 T 23-04-2016 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 811 827 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 SUPERFAMILY SSF52151 1199 1326 2.88E-64 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 SUPERFAMILY SSF52151 1388 1489 2.88E-64 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 PANTHER PTHR11712:SF242 1109 1488 0.0 T 23-04-2016 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 PANTHER PTHR11712 556 1084 0.0 T 23-04-2016 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Gene3D G3DSA:3.40.50.980 198 361 2.6E-26 T 23-04-2016 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Gene3D G3DSA:3.40.50.980 11 197 2.0E-33 T 23-04-2016 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Gene3D G3DSA:3.40.47.10 650 910 1.2E-92 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 PANTHER PTHR11712 1109 1488 0.0 T 23-04-2016 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 SUPERFAMILY SSF53901 644 1019 3.92E-104 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Gene3D G3DSA:3.40.47.10 911 1074 6.5E-64 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Gene3D G3DSA:2.30.38.10 365 436 8.2E-21 T 23-04-2016 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 PANTHER PTHR11712:SF242 556 1084 0.0 T 23-04-2016 DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 SMART SM00825 Beta-ketoacyl synthase 650 1075 7.4E-218 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Pfam PF00698 Acyl transferase domain 1201 1489 2.8E-53 T 23-04-2016 IPR014043 Acyl transferase DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 648 898 2.1E-92 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS01090 24613d99b568f9836680d6827ac71bb7 1644 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 530 3.0E-14 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS38605 437d568829275e10fb90819db36257e6 231 Gene3D G3DSA:1.10.260.40 11 85 1.4E-19 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS38605 437d568829275e10fb90819db36257e6 231 SUPERFAMILY SSF51182 69 190 1.78E-17 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS38605 437d568829275e10fb90819db36257e6 231 Pfam PF07883 Cupin domain 133 180 4.6E-9 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS38605 437d568829275e10fb90819db36257e6 231 SUPERFAMILY SSF47413 14 79 2.34E-15 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS38605 437d568829275e10fb90819db36257e6 231 PANTHER PTHR10245:SF9 1 190 1.2E-28 T 23-04-2016 DC74_RS38605 437d568829275e10fb90819db36257e6 231 SMART SM00530 21 76 1.8E-13 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS38605 437d568829275e10fb90819db36257e6 231 PANTHER PTHR10245 1 190 1.2E-28 T 23-04-2016 DC74_RS38605 437d568829275e10fb90819db36257e6 231 Pfam PF01381 Helix-turn-helix 22 76 2.7E-13 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS38605 437d568829275e10fb90819db36257e6 231 Gene3D G3DSA:2.60.120.10 105 189 4.2E-15 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS00110 ab13cf0984ae202b2c48c76d1c303004 105 PANTHER PTHR33164 1 97 2.3E-15 T 23-04-2016 DC74_RS00110 ab13cf0984ae202b2c48c76d1c303004 105 PRINTS PR00598 Bacterial regulatory protein MarR family signature 28 43 3.3E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS00110 ab13cf0984ae202b2c48c76d1c303004 105 PRINTS PR00598 Bacterial regulatory protein MarR family signature 11 27 3.3E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS00110 ab13cf0984ae202b2c48c76d1c303004 105 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 3.3E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS00110 ab13cf0984ae202b2c48c76d1c303004 105 Pfam PF01047 MarR family 1 51 1.0E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS00110 ab13cf0984ae202b2c48c76d1c303004 105 PANTHER PTHR33164:SF16 1 97 2.3E-15 T 23-04-2016 DC74_RS00110 ab13cf0984ae202b2c48c76d1c303004 105 SUPERFAMILY SSF46785 1 98 2.3E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00110 ab13cf0984ae202b2c48c76d1c303004 105 Gene3D G3DSA:1.10.10.10 1 95 6.7E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00110 ab13cf0984ae202b2c48c76d1c303004 105 SMART SM00347 1 87 6.8E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 PANTHER PTHR11958:SF59 21 439 1.3E-203 T 23-04-2016 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 SUPERFAMILY SSF118215 27 415 2.48E-102 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 Gene3D G3DSA:1.10.3860.10 21 419 1.2E-109 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 Pfam PF00375 Sodium:dicarboxylate symporter family 27 414 3.7E-112 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 PRINTS PR00173 Glutamate-aspartate symporter signature 97 122 1.1E-27 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 PRINTS PR00173 Glutamate-aspartate symporter signature 309 335 1.1E-27 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 PRINTS PR00173 Glutamate-aspartate symporter signature 67 87 1.1E-27 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 PRINTS PR00173 Glutamate-aspartate symporter signature 242 261 1.1E-27 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 PRINTS PR00173 Glutamate-aspartate symporter signature 370 390 1.1E-27 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 PRINTS PR00173 Glutamate-aspartate symporter signature 207 226 1.1E-27 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 PRINTS PR00173 Glutamate-aspartate symporter signature 25 45 1.1E-27 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 PRINTS PR00173 Glutamate-aspartate symporter signature 344 363 1.1E-27 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS19205 391b8f5ffd32feb511387c5818eb42b0 458 PANTHER PTHR11958 21 439 1.3E-203 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS23480 c68d930fd9cd64345878e1a42d528f90 309 Gene3D G3DSA:3.40.1190.20 34 304 2.6E-83 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS23480 c68d930fd9cd64345878e1a42d528f90 309 Pfam PF00294 pfkB family carbohydrate kinase 12 286 1.8E-51 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS23480 c68d930fd9cd64345878e1a42d528f90 309 PANTHER PTHR10584:SF170 1 296 6.2E-98 T 23-04-2016 DC74_RS23480 c68d930fd9cd64345878e1a42d528f90 309 PANTHER PTHR10584 1 296 6.2E-98 T 23-04-2016 DC74_RS23480 c68d930fd9cd64345878e1a42d528f90 309 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 302 1.5E-96 T 23-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 DC74_RS23480 c68d930fd9cd64345878e1a42d528f90 309 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 23-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 DC74_RS23480 c68d930fd9cd64345878e1a42d528f90 309 PIRSF PIRSF000535 1 305 6.3E-87 T 23-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 DC74_RS23480 c68d930fd9cd64345878e1a42d528f90 309 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 23-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 DC74_RS23480 c68d930fd9cd64345878e1a42d528f90 309 SUPERFAMILY SSF53613 1 283 1.54E-66 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS18100 34f25afaf015768418f89bf45acae6c0 939 PANTHER PTHR21581:SF3 299 378 2.0E-97 T 23-04-2016 DC74_RS18100 34f25afaf015768418f89bf45acae6c0 939 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 600 808 4.4E-28 T 23-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 DC74_RS18100 34f25afaf015768418f89bf45acae6c0 939 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 606 617 3.9E-13 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 DC74_RS18100 34f25afaf015768418f89bf45acae6c0 939 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 694 707 3.9E-13 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 DC74_RS18100 34f25afaf015768418f89bf45acae6c0 939 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 665 682 3.9E-13 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 DC74_RS18100 34f25afaf015768418f89bf45acae6c0 939 PANTHER PTHR21581 299 378 2.0E-97 T 23-04-2016 DC74_RS18100 34f25afaf015768418f89bf45acae6c0 939 PANTHER PTHR21581 452 801 2.0E-97 T 23-04-2016 DC74_RS18100 34f25afaf015768418f89bf45acae6c0 939 SUPERFAMILY SSF56601 529 812 1.67E-35 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS18100 34f25afaf015768418f89bf45acae6c0 939 Gene3D G3DSA:3.40.710.10 599 811 2.2E-48 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS18100 34f25afaf015768418f89bf45acae6c0 939 PANTHER PTHR21581:SF3 452 801 2.0E-97 T 23-04-2016 DC74_RS05240 827bd7846607402ce3ce4519c4c6f2de 535 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 108 440 3.9E-70 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain DC74_RS05240 827bd7846607402ce3ce4519c4c6f2de 535 Gene3D G3DSA:3.10.105.10 310 497 9.1E-34 T 23-04-2016 DC74_RS05240 827bd7846607402ce3ce4519c4c6f2de 535 PANTHER PTHR30290 14 535 8.3E-90 T 23-04-2016 DC74_RS05240 827bd7846607402ce3ce4519c4c6f2de 535 Gene3D G3DSA:3.40.190.10 172 309 4.5E-34 T 23-04-2016 DC74_RS05240 827bd7846607402ce3ce4519c4c6f2de 535 PIRSF PIRSF002741 22 533 5.1E-70 T 23-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DC74_RS05240 827bd7846607402ce3ce4519c4c6f2de 535 SUPERFAMILY SSF53850 58 534 1.18E-103 T 23-04-2016 DC74_RS03020 bce164305ac477c94ad7f51d637e7969 366 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 331 2.1E-26 T 23-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS03020 bce164305ac477c94ad7f51d637e7969 366 Gene3D G3DSA:3.40.47.10 7 164 2.0E-50 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS03020 bce164305ac477c94ad7f51d637e7969 366 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 190 8.2E-27 T 23-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS03020 bce164305ac477c94ad7f51d637e7969 366 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 6 331 57.554 T 23-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS03020 bce164305ac477c94ad7f51d637e7969 366 PANTHER PTHR34069 7 338 2.4E-114 T 23-04-2016 DC74_RS03020 bce164305ac477c94ad7f51d637e7969 366 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 8 331 1.9E-90 T 23-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS03020 bce164305ac477c94ad7f51d637e7969 366 PANTHER PTHR34069:SF2 7 338 2.4E-114 T 23-04-2016 DC74_RS03020 bce164305ac477c94ad7f51d637e7969 366 Gene3D G3DSA:3.40.47.10 165 332 4.6E-43 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS03020 bce164305ac477c94ad7f51d637e7969 366 SUPERFAMILY SSF53901 6 331 8.73E-57 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SUPERFAMILY SSF58104 153 326 8.11E-6 T 23-04-2016 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1058 1182 3.1E-25 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 PANTHER PTHR24423 28 54 4.9E-134 T 23-04-2016 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 PANTHER PTHR24423 914 1187 4.9E-134 T 23-04-2016 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 PANTHER PTHR24423 1300 1426 4.9E-134 T 23-04-2016 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 PANTHER PTHR24423 1214 1282 4.9E-134 T 23-04-2016 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SMART SM00448 1301 1415 5.9E-36 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 Gene3D G3DSA:3.30.565.10 997 1183 6.9E-43 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 Gene3D G3DSA:3.40.50.2300 1300 1425 1.9E-39 T 23-04-2016 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 Pfam PF00072 Response regulator receiver domain 1303 1412 3.7E-24 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SUPERFAMILY SSF55781 717 893 2.35E-22 T 23-04-2016 IPR029016 GAF domain-like DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SMART SM00388 942 1010 1.1E-20 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 Pfam PF13185 GAF domain 749 892 4.1E-15 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 Gene3D G3DSA:1.10.287.130 937 996 3.7E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SUPERFAMILY SSF58104 513 642 3.14E-11 T 23-04-2016 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SUPERFAMILY SSF58104 329 510 2.28E-12 T 23-04-2016 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SUPERFAMILY SSF52172 1298 1420 9.53E-38 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SMART SM00304 309 361 2.6E-8 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SMART SM00304 120 177 0.0063 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SMART SM00304 23 80 91.0 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SMART SM00304 677 729 2.5E-7 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SMART SM00304 217 269 1.3E-8 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SMART SM00304 401 453 2.7E-7 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SMART SM00304 585 637 7.4E-9 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SMART SM00304 493 545 7.8E-10 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SMART SM00387 1057 1184 1.4E-35 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 943 1010 6.6E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 Gene3D G3DSA:3.30.450.40 725 893 6.8E-17 T 23-04-2016 IPR029016 GAF domain-like DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SMART SM00065 750 902 0.0017 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SUPERFAMILY SSF55874 999 1185 3.93E-43 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1109 1123 9.68E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1144 1162 9.68E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1127 1137 9.68E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1168 1181 9.68E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS21395 4cfb8d4492f8d47f474f70da3956ae96 1467 SUPERFAMILY SSF47384 929 1011 2.94E-18 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS11725 d147bcda76bd682b70b27563436d778c 105 PANTHER PTHR21496 1 99 2.5E-31 T 23-04-2016 DC74_RS11725 d147bcda76bd682b70b27563436d778c 105 Pfam PF00355 Rieske [2Fe-2S] domain 5 89 1.2E-20 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS11725 d147bcda76bd682b70b27563436d778c 105 Gene3D G3DSA:2.102.10.10 1 103 4.5E-34 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS11725 d147bcda76bd682b70b27563436d778c 105 SUPERFAMILY SSF50022 1 103 3.8E-31 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS23505 127e73ada082d5a140eca63241931ae9 324 PANTHER PTHR10788 49 301 3.1E-15 T 23-04-2016 DC74_RS23505 127e73ada082d5a140eca63241931ae9 324 SUPERFAMILY SSF56784 46 297 3.47E-31 T 23-04-2016 IPR023214 HAD-like domain DC74_RS23505 127e73ada082d5a140eca63241931ae9 324 Pfam PF02358 Trehalose-phosphatase 49 269 8.5E-22 T 23-04-2016 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 DC74_RS23505 127e73ada082d5a140eca63241931ae9 324 Gene3D G3DSA:3.40.50.1000 45 125 1.2E-35 T 23-04-2016 IPR023214 HAD-like domain DC74_RS23505 127e73ada082d5a140eca63241931ae9 324 Gene3D G3DSA:3.40.50.1000 210 301 1.2E-35 T 23-04-2016 IPR023214 HAD-like domain DC74_RS23505 127e73ada082d5a140eca63241931ae9 324 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 44 297 3.3E-31 T 23-04-2016 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 DC74_RS17200 e1ca033072bddfe41865cd95d450c4cb 122 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 14 117 2.5E-27 T 23-04-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 DC74_RS17200 e1ca033072bddfe41865cd95d450c4cb 122 SUPERFAMILY SSF52091 15 121 2.16E-28 T 23-04-2016 IPR002645 STAS domain DC74_RS17200 e1ca033072bddfe41865cd95d450c4cb 122 Pfam PF13466 STAS domain 27 105 5.2E-18 T 23-04-2016 IPR002645 STAS domain DC74_RS17200 e1ca033072bddfe41865cd95d450c4cb 122 Gene3D G3DSA:3.30.750.24 14 121 1.3E-36 T 23-04-2016 IPR002645 STAS domain DC74_RS17200 e1ca033072bddfe41865cd95d450c4cb 122 PANTHER PTHR33495 1 122 8.6E-40 T 23-04-2016 DC74_RS17200 e1ca033072bddfe41865cd95d450c4cb 122 PANTHER PTHR33495:SF2 1 122 8.6E-40 T 23-04-2016 DC74_RS34235 cda7b33a0e96e102f5387f63ce711742 251 PANTHER PTHR13832:SF278 7 247 1.8E-34 T 23-04-2016 DC74_RS34235 cda7b33a0e96e102f5387f63ce711742 251 SMART SM00332 6 247 9.1E-18 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS34235 cda7b33a0e96e102f5387f63ce711742 251 Gene3D G3DSA:3.60.40.10 9 248 3.9E-49 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS34235 cda7b33a0e96e102f5387f63ce711742 251 PANTHER PTHR13832 7 247 1.8E-34 T 23-04-2016 IPR015655 Protein phosphatase 2C family GO:0004722|GO:0006470 KEGG: 04660+3.1.3.16 DC74_RS34235 cda7b33a0e96e102f5387f63ce711742 251 SUPERFAMILY SSF81606 9 249 3.27E-44 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS34235 cda7b33a0e96e102f5387f63ce711742 251 SMART SM00331 34 249 2.0E-4 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS34235 cda7b33a0e96e102f5387f63ce711742 251 Pfam PF13672 Protein phosphatase 2C 55 212 7.7E-16 T 23-04-2016 DC74_RS19450 8b8a48cb46f910cdd6f3d41d321f116e 264 Pfam PF02629 CoA binding domain 91 188 6.9E-21 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS19450 8b8a48cb46f910cdd6f3d41d321f116e 264 PANTHER PTHR35786 3 225 9.7E-117 T 23-04-2016 DC74_RS19450 8b8a48cb46f910cdd6f3d41d321f116e 264 Pfam PF06971 Putative DNA-binding protein N-terminus 16 63 3.9E-19 T 23-04-2016 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 DC74_RS19450 8b8a48cb46f910cdd6f3d41d321f116e 264 Gene3D G3DSA:3.40.50.720 88 221 2.2E-50 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19450 8b8a48cb46f910cdd6f3d41d321f116e 264 PANTHER PTHR35786:SF1 3 225 9.7E-117 T 23-04-2016 DC74_RS19450 8b8a48cb46f910cdd6f3d41d321f116e 264 SUPERFAMILY SSF51735 93 214 9.84E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19450 8b8a48cb46f910cdd6f3d41d321f116e 264 SMART SM00881 89 190 1.5E-16 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS19450 8b8a48cb46f910cdd6f3d41d321f116e 264 Gene3D G3DSA:1.10.10.10 15 85 2.5E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19450 8b8a48cb46f910cdd6f3d41d321f116e 264 SUPERFAMILY SSF46785 17 89 1.33E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19450 8b8a48cb46f910cdd6f3d41d321f116e 264 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 11 219 36.517 T 23-04-2016 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 Pfam PF03144 Elongation factor Tu domain 2 350 426 7.8E-10 T 23-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 Pfam PF00679 Elongation factor G C-terminus 637 722 5.7E-19 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 SMART SM00838 636 724 1.3E-14 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 Gene3D G3DSA:3.30.70.240 639 725 9.9E-21 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 SUPERFAMILY SSF54980 637 729 4.08E-20 T 23-04-2016 IPR009022 Elongation factor G, III-V domain DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 Pfam PF14492 Elongation Factor G, domain II 440 512 8.8E-25 T 23-04-2016 IPR009022 Elongation factor G, III-V domain DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 Pfam PF00009 Elongation factor Tu GTP binding domain 24 170 1.0E-28 T 23-04-2016 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 SUPERFAMILY SSF52540 21 307 7.71E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 Gene3D G3DSA:3.30.70.870 441 512 2.7E-25 T 23-04-2016 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 Pfam PF03764 Elongation factor G, domain IV 516 632 2.7E-38 T 23-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 PANTHER PTHR23115 329 728 5.8E-263 T 23-04-2016 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 PANTHER PTHR23115 276 309 5.8E-263 T 23-04-2016 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 PANTHER PTHR23115 7 195 5.8E-263 T 23-04-2016 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 PANTHER PTHR23115:SF98 329 728 5.8E-263 T 23-04-2016 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 PANTHER PTHR23115:SF98 276 309 5.8E-263 T 23-04-2016 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 PANTHER PTHR23115:SF98 7 195 5.8E-263 T 23-04-2016 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 SUPERFAMILY SSF54980 440 517 2.37E-18 T 23-04-2016 IPR009022 Elongation factor G, III-V domain DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 PRINTS PR00315 GTP-binding elongation factor signature 92 102 5.0E-6 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 PRINTS PR00315 GTP-binding elongation factor signature 108 119 5.0E-6 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 PRINTS PR00315 GTP-binding elongation factor signature 26 39 5.0E-6 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 SUPERFAMILY SSF50447 326 437 5.81E-23 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 SUPERFAMILY SSF54211 516 632 5.56E-34 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 Gene3D G3DSA:3.40.50.300 19 313 1.4E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 SMART SM00889 516 634 1.6E-55 T 23-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 Gene3D G3DSA:2.40.30.10 330 440 2.5E-27 T 23-04-2016 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 160 2.0E-14 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 DC74_RS09660 bdcdb78c3f88660d5d2be52a90d7fe6a 732 Gene3D G3DSA:3.30.230.10 520 638 9.5E-45 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS22365 7d7ed71ce9f2f26685f40fb3f2694813 485 SUPERFAMILY SSF53720 10 479 9.42E-145 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS22365 7d7ed71ce9f2f26685f40fb3f2694813 485 PANTHER PTHR11699 1 485 3.8E-263 T 23-04-2016 DC74_RS22365 7d7ed71ce9f2f26685f40fb3f2694813 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS22365 7d7ed71ce9f2f26685f40fb3f2694813 485 PANTHER PTHR11699:SF203 1 485 3.8E-263 T 23-04-2016 DC74_RS22365 7d7ed71ce9f2f26685f40fb3f2694813 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS22365 7d7ed71ce9f2f26685f40fb3f2694813 485 Gene3D G3DSA:3.40.605.10 11 267 6.7E-76 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS22365 7d7ed71ce9f2f26685f40fb3f2694813 485 Pfam PF00171 Aldehyde dehydrogenase family 18 474 3.2E-147 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS22365 7d7ed71ce9f2f26685f40fb3f2694813 485 Gene3D G3DSA:3.40.309.10 268 450 2.0E-62 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS21295 b9b8cd1cd0418865bc5b7fd66ffe8859 322 Gene3D G3DSA:3.10.450.50 13 44 4.0E-8 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS21295 b9b8cd1cd0418865bc5b7fd66ffe8859 322 SUPERFAMILY SSF103642 25 44 1.1E-6 T 23-04-2016 DC74_RS21295 b9b8cd1cd0418865bc5b7fd66ffe8859 322 Pfam PF02810 SEC-C motif 28 44 5.4E-8 T 23-04-2016 IPR004027 SEC-C motif DC74_RS04810 7255caf6484fa3015fa4f5be8e7c8b3e 102 Pfam PF01161 Phosphatidylethanolamine-binding protein 1 99 2.2E-17 T 23-04-2016 IPR008914 Phosphatidylethanolamine-binding protein DC74_RS04810 7255caf6484fa3015fa4f5be8e7c8b3e 102 Gene3D G3DSA:3.90.280.10 2 102 6.4E-22 T 23-04-2016 IPR008914 Phosphatidylethanolamine-binding protein DC74_RS04810 7255caf6484fa3015fa4f5be8e7c8b3e 102 SUPERFAMILY SSF49777 3 99 3.53E-20 T 23-04-2016 IPR008914 Phosphatidylethanolamine-binding protein DC74_RS29635 eb71a3dfc7516bc216f9be72756798c8 292 Pfam PF02195 ParB-like nuclease domain 6 50 3.8E-5 T 23-04-2016 IPR003115 ParB/Sulfiredoxin DC74_RS29635 eb71a3dfc7516bc216f9be72756798c8 292 Gene3D G3DSA:3.90.1530.10 5 50 4.6E-7 T 23-04-2016 DC74_RS29635 eb71a3dfc7516bc216f9be72756798c8 292 SUPERFAMILY SSF110849 5 90 1.2E-10 T 23-04-2016 IPR003115 ParB/Sulfiredoxin DC74_RS16130 cf419776afc4dd87a8af342bf0f64647 613 SUPERFAMILY SSF56801 32 555 1.83E-97 T 23-04-2016 DC74_RS16130 cf419776afc4dd87a8af342bf0f64647 613 Gene3D G3DSA:3.30.300.30 455 550 8.8E-13 T 23-04-2016 DC74_RS16130 cf419776afc4dd87a8af342bf0f64647 613 Pfam PF00501 AMP-binding enzyme 35 454 6.2E-64 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS16130 cf419776afc4dd87a8af342bf0f64647 613 Pfam PF13193 AMP-binding enzyme C-terminal domain 465 541 1.1E-7 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS16130 cf419776afc4dd87a8af342bf0f64647 613 Gene3D G3DSA:3.40.50.980 36 199 4.6E-17 T 23-04-2016 DC74_RS16130 cf419776afc4dd87a8af342bf0f64647 613 Gene3D G3DSA:3.40.50.980 200 352 1.4E-21 T 23-04-2016 DC74_RS16130 cf419776afc4dd87a8af342bf0f64647 613 Gene3D G3DSA:2.30.38.10 353 445 1.8E-19 T 23-04-2016 DC74_RS16130 cf419776afc4dd87a8af342bf0f64647 613 PANTHER PTHR24096:SF192 32 552 3.5E-96 T 23-04-2016 IPR030310 Long-chain-fatty-acid--CoA ligase FadD17 GO:0004467|GO:0006633 DC74_RS16130 cf419776afc4dd87a8af342bf0f64647 613 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS16130 cf419776afc4dd87a8af342bf0f64647 613 PANTHER PTHR24096 32 552 3.5E-96 T 23-04-2016 DC74_RS27810 7a21fb1782d5831b84e8e75e1cbe22c3 596 SUPERFAMILY SSF82549 10 344 5.49E-101 T 23-04-2016 DC74_RS27810 7a21fb1782d5831b84e8e75e1cbe22c3 596 Gene3D G3DSA:3.30.1180.20 196 344 1.2E-44 T 23-04-2016 DC74_RS27810 7a21fb1782d5831b84e8e75e1cbe22c3 596 SMART SM01120 413 593 1.2E-38 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 DC74_RS27810 7a21fb1782d5831b84e8e75e1cbe22c3 596 Pfam PF02733 Dak1 domain 21 342 2.7E-104 T 23-04-2016 IPR004006 DhaK domain GO:0004371|GO:0006071 DC74_RS27810 7a21fb1782d5831b84e8e75e1cbe22c3 596 SUPERFAMILY SSF101473 392 591 1.09E-37 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 DC74_RS27810 7a21fb1782d5831b84e8e75e1cbe22c3 596 Gene3D G3DSA:3.40.50.10440 18 193 7.0E-56 T 23-04-2016 DC74_RS27810 7a21fb1782d5831b84e8e75e1cbe22c3 596 PANTHER PTHR28629 12 596 5.1E-159 T 23-04-2016 DC74_RS27810 7a21fb1782d5831b84e8e75e1cbe22c3 596 Pfam PF02734 DAK2 domain 414 591 2.2E-35 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 DC74_RS02535 f0923977db33746960416575f9ee01fe 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02535 f0923977db33746960416575f9ee01fe 219 PANTHER PTHR26402 15 216 6.8E-73 T 23-04-2016 DC74_RS02535 f0923977db33746960416575f9ee01fe 219 PANTHER PTHR26402:SF151 15 216 6.8E-73 T 23-04-2016 DC74_RS02535 f0923977db33746960416575f9ee01fe 219 Pfam PF00072 Response regulator receiver domain 18 129 2.6E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS02535 f0923977db33746960416575f9ee01fe 219 Gene3D G3DSA:3.40.50.2300 14 133 1.6E-34 T 23-04-2016 DC74_RS02535 f0923977db33746960416575f9ee01fe 219 SUPERFAMILY SSF46894 146 218 7.48E-21 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS02535 f0923977db33746960416575f9ee01fe 219 SMART SM00448 15 129 3.9E-32 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS02535 f0923977db33746960416575f9ee01fe 219 SUPERFAMILY SSF52172 15 147 1.08E-31 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS02535 f0923977db33746960416575f9ee01fe 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 211 7.3E-17 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02535 f0923977db33746960416575f9ee01fe 219 Gene3D G3DSA:1.10.10.10 134 218 3.2E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02535 f0923977db33746960416575f9ee01fe 219 SMART SM00421 155 212 2.0E-22 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02535 f0923977db33746960416575f9ee01fe 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.1E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02535 f0923977db33746960416575f9ee01fe 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.1E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02535 f0923977db33746960416575f9ee01fe 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.1E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS33185 10524c319b232b8096fe52cdab33dd28 353 PIRSF PIRSF000112 1 353 4.6E-99 T 23-04-2016 DC74_RS33185 10524c319b232b8096fe52cdab33dd28 353 Gene3D G3DSA:3.40.50.1970 7 157 7.6E-28 T 23-04-2016 DC74_RS33185 10524c319b232b8096fe52cdab33dd28 353 PANTHER PTHR11496:SF67 1 353 1.4E-176 T 23-04-2016 DC74_RS33185 10524c319b232b8096fe52cdab33dd28 353 SUPERFAMILY SSF56796 2 344 2.62E-58 T 23-04-2016 DC74_RS33185 10524c319b232b8096fe52cdab33dd28 353 Gene3D G3DSA:1.20.1090.10 159 347 1.4E-59 T 23-04-2016 DC74_RS33185 10524c319b232b8096fe52cdab33dd28 353 PANTHER PTHR11496 1 353 1.4E-176 T 23-04-2016 DC74_RS33185 10524c319b232b8096fe52cdab33dd28 353 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 270 6.4E-55 T 23-04-2016 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|KEGG: 00630+1.1.1.26|MetaCyc: PWY-6349|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00940 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2113 2293 1.2E-49 T 23-04-2016 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SUPERFAMILY SSF51735 1574 1757 9.84E-15 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SUPERFAMILY SSF53901 8 379 4.94E-82 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SUPERFAMILY SSF53901 411 429 4.94E-82 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 172 188 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SUPERFAMILY SSF53335 1365 1551 1.13E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1796 1859 6.3E-6 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SUPERFAMILY SSF55048 661 725 2.09E-10 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SUPERFAMILY SSF51735 2111 2340 1.27E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 538 838 4.2E-102 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Pfam PF00107 Zinc-binding dehydrogenase 1921 2036 6.3E-25 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SMART SM00829 1778 2092 5.9E-151 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Pfam PF14765 Polyketide synthase dehydratase 902 1172 2.7E-51 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 267 383 4.5E-36 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Gene3D G3DSA:3.40.50.720 1917 2009 2.6E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Gene3D G3DSA:3.40.366.10 725 836 1.3E-68 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Gene3D G3DSA:3.40.366.10 535 657 1.3E-68 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2416 2431 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SUPERFAMILY SSF52151 727 828 6.28E-64 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SUPERFAMILY SSF52151 535 663 6.28E-64 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Pfam PF08242 Methyltransferase domain 1394 1494 3.6E-17 T 23-04-2016 IPR013217 Methyltransferase type 12 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SUPERFAMILY SSF51735 1886 2050 5.41E-47 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 387 499 1.8E-16 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SUPERFAMILY SSF50129 1772 1919 7.7E-29 T 23-04-2016 IPR011032 GroES-like DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Gene3D G3DSA:3.40.47.10 273 436 3.1E-52 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Gene3D G3DSA:1.10.1200.10 2385 2457 1.2E-9 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Gene3D G3DSA:3.30.70.250 660 719 1.8E-6 T 23-04-2016 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 PANTHER PTHR11712 11 2444 0.0 T 23-04-2016 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 258 1.1E-71 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Gene3D G3DSA:3.90.180.10 1782 1916 1.7E-41 T 23-04-2016 IPR011032 GroES-like DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SMART SM00826 901 1062 1.6E-28 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Gene3D G3DSA:3.40.47.10 10 271 4.6E-86 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SMART SM00823 Phosphopantetheine attachment site 2389 2448 9.6E-4 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Gene3D G3DSA:3.40.50.150 1366 1549 1.6E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SMART SM00825 Beta-ketoacyl synthase 11 435 2.3E-172 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 SUPERFAMILY SSF47336 2387 2460 3.01E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Gene3D G3DSA:3.40.50.720 2115 2295 8.0E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Pfam PF08659 KR domain 2113 2291 1.3E-58 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Pfam PF00550 Phosphopantetheine attachment site 2393 2454 8.0E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04530 f3d8d010b9b6281e189dad4d6a330074 2465 Pfam PF00698 Acyl transferase domain 537 828 4.9E-62 T 23-04-2016 IPR014043 Acyl transferase DC74_RS20710 89e08438ee1b232524783acba36ed96d 376 Pfam PF02096 60Kd inner membrane protein 35 252 9.0E-58 T 23-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 DC74_RS20710 89e08438ee1b232524783acba36ed96d 376 PANTHER PTHR12428 4 141 2.9E-64 T 23-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 DC74_RS20710 89e08438ee1b232524783acba36ed96d 376 PANTHER PTHR12428:SF14 4 141 2.9E-64 T 23-04-2016 DC74_RS20710 89e08438ee1b232524783acba36ed96d 376 PANTHER PTHR12428:SF14 171 371 2.9E-64 T 23-04-2016 DC74_RS20710 89e08438ee1b232524783acba36ed96d 376 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 35 252 9.5E-62 T 23-04-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal DC74_RS20710 89e08438ee1b232524783acba36ed96d 376 PANTHER PTHR12428 171 371 2.9E-64 T 23-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 DC74_RS34050 af2f9e260798af5b0972ec9a1964d0c1 392 PANTHER PTHR30383 31 389 1.3E-86 T 23-04-2016 DC74_RS34050 af2f9e260798af5b0972ec9a1964d0c1 392 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 187 382 1.1E-25 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS34050 af2f9e260798af5b0972ec9a1964d0c1 392 Gene3D G3DSA:3.40.50.1110 185 387 8.5E-29 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS34050 af2f9e260798af5b0972ec9a1964d0c1 392 SUPERFAMILY SSF52266 181 389 8.99E-42 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS34050 af2f9e260798af5b0972ec9a1964d0c1 392 PANTHER PTHR30383:SF3 31 389 1.3E-86 T 23-04-2016 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 PANTHER PTHR22845:SF4 143 625 2.0E-54 T 23-04-2016 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 Pfam PF00931 NB-ARC domain 306 525 3.2E-10 T 23-04-2016 IPR002182 NB-ARC GO:0043531 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 Pfam PF03704 Bacterial transcriptional activator domain 101 245 1.0E-21 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 SUPERFAMILY SSF48452 709 858 4.93E-13 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 Pfam PF13424 Tetratricopeptide repeat 888 951 6.3E-9 T 23-04-2016 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 Pfam PF13181 Tetratricopeptide repeat 810 838 0.099 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 SUPERFAMILY SSF46894 4 87 1.76E-10 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 85 6.3E-6 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 SUPERFAMILY SSF48452 96 264 3.8E-24 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 Gene3D G3DSA:3.40.50.300 307 398 7.7E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 SUPERFAMILY SSF52540 271 534 3.07E-28 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 PRINTS PR00364 Disease resistance protein signature 304 319 6.8E-9 T 23-04-2016 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 PRINTS PR00364 Disease resistance protein signature 383 397 6.8E-9 T 23-04-2016 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 PRINTS PR00364 Disease resistance protein signature 467 481 6.8E-9 T 23-04-2016 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 SMART SM00028 970 1003 230.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 SMART SM00028 730 763 45.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 SMART SM00028 850 883 0.0017 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 SMART SM00028 810 843 3.7 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 SMART SM00028 930 963 27.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 SMART SM01043 101 245 5.7E-24 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 Gene3D G3DSA:1.25.40.10 706 763 1.1E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 Gene3D G3DSA:1.25.40.10 784 1002 5.8E-30 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 SUPERFAMILY SSF48452 845 1005 8.39E-23 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 Pfam PF13176 Tetratricopeptide repeat 852 884 1.3E-4 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 PANTHER PTHR22845 143 625 2.0E-54 T 23-04-2016 DC74_RS20060 9a410cf8049840a6087fe6e98be2177a 1029 Gene3D G3DSA:1.10.10.10 12 89 3.4E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 SUPERFAMILY SSF46894 120 189 5.1E-20 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 128 183 2.2E-18 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 PANTHER PTHR26402 6 184 1.9E-44 T 23-04-2016 DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 SMART SM00448 2 99 2.1E-8 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 SMART SM00421 126 183 1.1E-23 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 Gene3D G3DSA:3.40.50.2300 3 131 4.9E-23 T 23-04-2016 DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 Pfam PF00072 Response regulator receiver domain 6 100 9.4E-16 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 143 170 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 Gene3D G3DSA:1.10.10.10 132 188 4.2E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 159 1.0E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 171 1.0E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 129 143 1.0E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 PANTHER PTHR26402:SF151 6 184 1.9E-44 T 23-04-2016 DC74_RS37280 cb7e790a1aa45791b6b06251394fd3ab 200 SUPERFAMILY SSF52172 4 103 7.4E-20 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 PANTHER PTHR30627 510 695 9.0E-203 T 23-04-2016 DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 PANTHER PTHR30627 2 475 9.0E-203 T 23-04-2016 DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 Pfam PF00905 Penicillin binding protein transpeptidase domain 298 657 2.9E-86 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 246 3.1E-38 T 23-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 Gene3D G3DSA:3.40.710.10 511 662 4.2E-92 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 Gene3D G3DSA:3.40.710.10 261 473 4.2E-92 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 SUPERFAMILY SSF56519 53 261 3.4E-36 T 23-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 16 661 1.9E-176 T 23-04-2016 IPR017790 Penicillin-binding protein 2 GO:0016020 UniPathway: UPA00219 DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 Gene3D G3DSA:3.90.1310.10 137 259 1.1E-28 T 23-04-2016 DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 PANTHER PTHR30627:SF2 510 695 9.0E-203 T 23-04-2016 DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 PANTHER PTHR30627:SF2 2 475 9.0E-203 T 23-04-2016 DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 SUPERFAMILY SSF56601 213 459 1.36E-84 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS15260 6648b15129c60729f86cba43186de9aa 713 SUPERFAMILY SSF56601 516 664 1.36E-84 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS19760 0532ed81c86da598186f18ecd5b7504f 411 Pfam PF07690 Major Facilitator Superfamily 36 368 4.8E-22 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS19760 0532ed81c86da598186f18ecd5b7504f 411 SUPERFAMILY SSF103473 20 406 1.07E-31 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS19760 0532ed81c86da598186f18ecd5b7504f 411 Gene3D G3DSA:1.20.1250.20 248 405 9.1E-8 T 23-04-2016 DC74_RS19760 0532ed81c86da598186f18ecd5b7504f 411 Gene3D G3DSA:1.20.1250.20 28 202 1.9E-15 T 23-04-2016 DC74_RS35810 26f72dea5b29c87d7eb304d57386b269 169 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 82 162 6.2E-31 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS35810 26f72dea5b29c87d7eb304d57386b269 169 SUPERFAMILY SSF46767 81 164 4.45E-29 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS35810 26f72dea5b29c87d7eb304d57386b269 169 PANTHER PTHR10815 4 164 2.9E-45 T 23-04-2016 DC74_RS35810 26f72dea5b29c87d7eb304d57386b269 169 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 83 163 1.4E-30 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS35810 26f72dea5b29c87d7eb304d57386b269 169 Gene3D G3DSA:1.10.10.10 81 166 1.0E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35810 26f72dea5b29c87d7eb304d57386b269 169 SUPERFAMILY SSF53155 3 87 5.1E-13 T 23-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 DC74_RS35810 26f72dea5b29c87d7eb304d57386b269 169 PANTHER PTHR10815:SF5 4 164 2.9E-45 T 23-04-2016 DC74_RS24870 add8e3771d159c389f72c3bc7cdf16d1 499 Pfam PF01494 FAD binding domain 1 338 6.2E-75 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS24870 add8e3771d159c389f72c3bc7cdf16d1 499 PANTHER PTHR13789:SF90 1 345 3.1E-84 T 23-04-2016 DC74_RS24870 add8e3771d159c389f72c3bc7cdf16d1 499 Gene3D G3DSA:3.50.50.60 262 345 9.1E-54 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24870 add8e3771d159c389f72c3bc7cdf16d1 499 Gene3D G3DSA:3.50.50.60 1 177 9.1E-54 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24870 add8e3771d159c389f72c3bc7cdf16d1 499 PANTHER PTHR13789 1 345 3.1E-84 T 23-04-2016 DC74_RS24870 add8e3771d159c389f72c3bc7cdf16d1 499 SUPERFAMILY SSF51905 261 352 1.95E-57 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24870 add8e3771d159c389f72c3bc7cdf16d1 499 SUPERFAMILY SSF51905 1 172 1.95E-57 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24870 add8e3771d159c389f72c3bc7cdf16d1 499 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 7.8E-33 T 23-04-2016 DC74_RS24870 add8e3771d159c389f72c3bc7cdf16d1 499 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 341 7.8E-33 T 23-04-2016 DC74_RS24870 add8e3771d159c389f72c3bc7cdf16d1 499 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 325 7.8E-33 T 23-04-2016 DC74_RS24870 add8e3771d159c389f72c3bc7cdf16d1 499 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 7.8E-33 T 23-04-2016 DC74_RS24870 add8e3771d159c389f72c3bc7cdf16d1 499 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 305 7.8E-33 T 23-04-2016 DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 Gene3D G3DSA:2.40.50.140 293 373 2.4E-41 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 Gene3D G3DSA:2.40.50.140 38 78 2.4E-41 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 SMART SM00382 414 599 3.6E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 Pfam PF07498 Rho termination factor, N-terminal domain 39 75 3.3E-10 T 23-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 Pfam PF07497 Rho termination factor, RNA-binding domain 298 372 2.8E-29 T 23-04-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 PANTHER PTHR15184 220 647 4.0E-169 T 23-04-2016 DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 403 607 4.9E-20 T 23-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 SUPERFAMILY SSF52540 336 614 6.6E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 TIGRFAM TIGR00767 rho: transcription termination factor Rho 39 661 2.6E-198 T 23-04-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 Hamap MF_01884 Transcription termination factor Rho [rho]. 283 663 201.414 T 23-04-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 Gene3D G3DSA:3.40.50.300 378 661 7.0E-98 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 SMART SM00959 38 80 3.5E-10 T 23-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 SUPERFAMILY SSF50249 298 372 2.57E-17 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 SMART SM00357 299 365 1.1E-11 T 23-04-2016 IPR011129 Cold shock protein GO:0003676 DC74_RS26865 2f9fc8ade217438e5e1f108b7c687aff 672 PANTHER PTHR15184:SF34 220 647 4.0E-169 T 23-04-2016 DC74_RS08915 66de4d5b7f0e5cd33e9dd602d6002be0 126 Gene3D G3DSA:3.40.30.10 38 89 8.0E-11 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS08915 66de4d5b7f0e5cd33e9dd602d6002be0 126 Pfam PF00085 Thioredoxin 38 112 1.3E-8 T 23-04-2016 IPR013766 Thioredoxin domain GO:0045454 DC74_RS08915 66de4d5b7f0e5cd33e9dd602d6002be0 126 SUPERFAMILY SSF52833 36 119 8.36E-15 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS08915 66de4d5b7f0e5cd33e9dd602d6002be0 126 Gene3D G3DSA:3.40.30.10 90 124 1.7E-4 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS29010 b99d15fdb6ea138e374b7551aaf013b1 269 Gene3D G3DSA:2.40.10.10 67 129 4.5E-19 T 23-04-2016 DC74_RS29010 b99d15fdb6ea138e374b7551aaf013b1 269 SUPERFAMILY SSF50494 12 260 2.48E-63 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS29010 b99d15fdb6ea138e374b7551aaf013b1 269 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 71 76 - T 23-04-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 DC74_RS29010 b99d15fdb6ea138e374b7551aaf013b1 269 PANTHER PTHR24276 1 261 3.6E-74 T 23-04-2016 DC74_RS29010 b99d15fdb6ea138e374b7551aaf013b1 269 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 124 138 2.8E-12 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS29010 b99d15fdb6ea138e374b7551aaf013b1 269 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 217 229 2.8E-12 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS29010 b99d15fdb6ea138e374b7551aaf013b1 269 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 61 76 2.8E-12 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS29010 b99d15fdb6ea138e374b7551aaf013b1 269 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 218 229 - T 23-04-2016 IPR033116 Serine proteases, trypsin family, serine active site DC74_RS29010 b99d15fdb6ea138e374b7551aaf013b1 269 Pfam PF00089 Trypsin 28 261 1.2E-54 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS29010 b99d15fdb6ea138e374b7551aaf013b1 269 Gene3D G3DSA:2.40.10.10 28 66 3.4E-13 T 23-04-2016 DC74_RS29010 b99d15fdb6ea138e374b7551aaf013b1 269 Gene3D G3DSA:2.40.10.10 130 260 1.1E-39 T 23-04-2016 DC74_RS29010 b99d15fdb6ea138e374b7551aaf013b1 269 SMART SM00020 27 263 1.7E-68 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PANTHER PTHR24322:SF649 177 208 3.0E-43 T 23-04-2016 DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PANTHER PTHR24322:SF649 34 161 3.0E-43 T 23-04-2016 DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 Gene3D G3DSA:3.40.50.720 26 269 3.0E-82 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 164 192 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 31 48 1.07E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 230 250 1.07E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 214 1.07E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 167 1.07E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 196 1.07E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 105 116 1.07E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 30 220 4.0E-5 T 23-04-2016 DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 36 267 1.5E-64 T 23-04-2016 DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PANTHER PTHR24322 177 208 3.0E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PANTHER PTHR24322 34 161 3.0E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 177 196 3.13E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 105 116 3.13E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 165 3.13E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17535 9e783902d6420ad01425db38dbcccecf 273 SUPERFAMILY SSF51735 29 268 1.33E-77 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS35415 2ef29a7ba8cc786eab683c68c74d9508 157 Gene3D G3DSA:3.90.1720.10 37 153 7.4E-39 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS35415 2ef29a7ba8cc786eab683c68c74d9508 157 PANTHER PTHR21666 47 155 7.0E-30 T 23-04-2016 DC74_RS35415 2ef29a7ba8cc786eab683c68c74d9508 157 Pfam PF00877 NlpC/P60 family 56 140 4.2E-24 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS35415 2ef29a7ba8cc786eab683c68c74d9508 157 SUPERFAMILY SSF54001 40 154 1.57E-36 T 23-04-2016 DC74_RS37840 cd5da447914d8bd376f3ee0e74bbf2b4 148 SMART SM00347 24 124 3.6E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS37840 cd5da447914d8bd376f3ee0e74bbf2b4 148 Pfam PF01047 MarR family 33 88 2.6E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS37840 cd5da447914d8bd376f3ee0e74bbf2b4 148 SUPERFAMILY SSF46785 9 136 4.97E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37840 cd5da447914d8bd376f3ee0e74bbf2b4 148 Gene3D G3DSA:1.10.10.10 10 136 2.4E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37840 cd5da447914d8bd376f3ee0e74bbf2b4 148 PANTHER PTHR39515 5 139 7.0E-21 T 23-04-2016 DC74_RS24025 fbd6675c3c44d93483a7c0aeda995e52 594 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 44 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS24025 fbd6675c3c44d93483a7c0aeda995e52 594 Pfam PF00069 Protein kinase domain 17 263 2.2E-46 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS24025 fbd6675c3c44d93483a7c0aeda995e52 594 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS24025 fbd6675c3c44d93483a7c0aeda995e52 594 Gene3D G3DSA:3.30.200.20 8 84 6.5E-24 T 23-04-2016 DC74_RS24025 fbd6675c3c44d93483a7c0aeda995e52 594 PANTHER PTHR24362 7 358 1.7E-78 T 23-04-2016 DC74_RS24025 fbd6675c3c44d93483a7c0aeda995e52 594 PANTHER PTHR24362 402 479 1.7E-78 T 23-04-2016 DC74_RS24025 fbd6675c3c44d93483a7c0aeda995e52 594 Gene3D G3DSA:1.10.510.10 85 265 6.8E-45 T 23-04-2016 DC74_RS24025 fbd6675c3c44d93483a7c0aeda995e52 594 SUPERFAMILY SSF56112 11 264 8.88E-66 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS24025 fbd6675c3c44d93483a7c0aeda995e52 594 PANTHER PTHR24362:SF160 7 358 1.7E-78 T 23-04-2016 DC74_RS24025 fbd6675c3c44d93483a7c0aeda995e52 594 PANTHER PTHR24362:SF160 402 479 1.7E-78 T 23-04-2016 DC74_RS24025 fbd6675c3c44d93483a7c0aeda995e52 594 SMART SM00220 15 277 3.2E-62 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 SUPERFAMILY SSF51735 10 256 3.21E-77 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 Gene3D G3DSA:3.40.50.720 10 257 4.6E-83 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 PANTHER PTHR24322 160 192 9.8E-55 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 PANTHER PTHR24322 14 144 9.8E-55 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.7E-14 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.7E-14 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.7E-14 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 7.5E-45 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 7.5E-45 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 7.5E-45 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 7.5E-45 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 7.5E-45 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 7.5E-45 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 255 2.6E-65 T 23-04-2016 DC74_RS37270 56f208e4ef72b1817ae504febfc06866 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS06070 3537771b34283dbc91a2ee0322385cb0 225 Gene3D G3DSA:3.40.50.300 4 224 1.9E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06070 3537771b34283dbc91a2ee0322385cb0 225 SMART SM00382 34 220 5.5E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS06070 3537771b34283dbc91a2ee0322385cb0 225 Pfam PF00005 ABC transporter 26 171 3.6E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS06070 3537771b34283dbc91a2ee0322385cb0 225 SUPERFAMILY SSF52540 4 224 2.66E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06070 3537771b34283dbc91a2ee0322385cb0 225 PANTHER PTHR24220:SF587 7 217 9.2E-89 T 23-04-2016 DC74_RS06070 3537771b34283dbc91a2ee0322385cb0 225 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS06070 3537771b34283dbc91a2ee0322385cb0 225 PANTHER PTHR24220 7 217 9.2E-89 T 23-04-2016 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 338 438 2.8E-14 T 23-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 Gene3D G3DSA:2.40.37.10 315 462 1.6E-48 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 PANTHER PTHR11482:SF5 31 460 2.4E-154 T 23-04-2016 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 93 111 - T 23-04-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 SUPERFAMILY SSF50621 303 462 5.44E-49 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 429 451 3.4E-24 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 346 364 3.4E-24 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 200 209 3.4E-24 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 PRINTS PR01181 Diaminopimelate decarboxylase signature 111 128 3.4E-24 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 42 461 5.0E-145 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 SUPERFAMILY SSF51419 63 328 1.05E-78 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 52 462 39.879 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 419 432 1.7E-17 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 317 336 1.7E-17 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 113 125 1.7E-17 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 93 111 1.7E-17 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 228 241 1.7E-17 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 Gene3D G3DSA:3.20.20.10 72 314 3.5E-94 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 PANTHER PTHR11482 31 460 2.4E-154 T 23-04-2016 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 71 327 8.7E-66 T 23-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 DC74_RS26845 b2ee342f7b33e59c7f42280d4aa8708e 463 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 267 280 - T 23-04-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Reactome: REACT_13 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 SUPERFAMILY SSF54211 476 572 1.29E-14 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 SUPERFAMILY SSF50447 236 366 1.21E-7 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 Pfam PF03764 Elongation factor G, domain IV 477 571 1.5E-17 T 23-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 Gene3D G3DSA:2.40.30.10 266 366 6.5E-8 T 23-04-2016 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 SUPERFAMILY SSF52540 3 249 1.98E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 544 561 4.9E-16 T 23-04-2016 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 495 509 4.9E-16 T 23-04-2016 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 112 135 4.9E-16 T 23-04-2016 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 510 532 4.9E-16 T 23-04-2016 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 SUPERFAMILY SSF54980 377 452 9.35E-8 T 23-04-2016 IPR009022 Elongation factor G, III-V domain DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 Gene3D G3DSA:3.40.50.300 3 155 3.5E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 Gene3D G3DSA:3.40.50.300 174 253 3.0E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 150 5.2E-29 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 SMART SM00889 465 572 1.2E-9 T 23-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 Gene3D G3DSA:3.30.70.870 379 451 4.5E-7 T 23-04-2016 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 Pfam PF00009 Elongation factor Tu GTP binding domain 6 249 4.6E-52 T 23-04-2016 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PANTHER PTHR23115:SF91 4 156 5.6E-109 T 23-04-2016 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PANTHER PTHR23115:SF91 219 641 5.6E-109 T 23-04-2016 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 23-04-2016 IPR031157 Tr-type G domain, conserved site DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PANTHER PTHR23115 4 156 5.6E-109 T 23-04-2016 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PANTHER PTHR23115 219 641 5.6E-109 T 23-04-2016 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 Gene3D G3DSA:3.30.230.10 477 575 7.2E-25 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PRINTS PR00315 GTP-binding elongation factor signature 54 62 1.4E-15 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.4E-15 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.4E-15 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.4E-15 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS38230 69a27ad6ad0b3a8c7aa5932124b45ed5 663 PRINTS PR00315 GTP-binding elongation factor signature 8 21 1.4E-15 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 35 45 - T 23-04-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 Gene3D G3DSA:3.20.20.10 14 227 2.3E-70 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 Pfam PF01168 Alanine racemase, N-terminal domain 12 234 8.9E-64 T 23-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 Hamap MF_01201 Alanine racemase. 5 376 32.48 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 TIGRFAM TIGR00492 alr: alanine racemase 8 377 2.9E-94 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 PANTHER PTHR30511:SF0 2 381 2.0E-147 T 23-04-2016 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 Gene3D G3DSA:2.40.37.10 228 378 3.5E-59 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 SMART SM01005 249 376 4.8E-67 T 23-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 SUPERFAMILY SSF50621 241 378 1.81E-48 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 PRINTS PR00992 Alanine racemase signature 207 234 4.4E-58 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 PRINTS PR00992 Alanine racemase signature 358 371 4.4E-58 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 PRINTS PR00992 Alanine racemase signature 282 297 4.4E-58 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 PRINTS PR00992 Alanine racemase signature 66 84 4.4E-58 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 PRINTS PR00992 Alanine racemase signature 265 280 4.4E-58 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 PRINTS PR00992 Alanine racemase signature 127 139 4.4E-58 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 PRINTS PR00992 Alanine racemase signature 30 46 4.4E-58 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 PRINTS PR00992 Alanine racemase signature 164 175 4.4E-58 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 PRINTS PR00992 Alanine racemase signature 303 320 4.4E-58 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 SUPERFAMILY SSF51419 12 250 3.2E-63 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 PANTHER PTHR30511 2 381 2.0E-147 T 23-04-2016 DC74_RS18540 37295a68b3a41a96ebda03279dcbf164 399 Pfam PF00842 Alanine racemase, C-terminal domain 249 375 3.2E-39 T 23-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS38025 78fdd9b9f98ee55c0c32fb5c931e1a14 243 SUPERFAMILY SSF56784 12 228 8.12E-33 T 23-04-2016 IPR023214 HAD-like domain DC74_RS38025 78fdd9b9f98ee55c0c32fb5c931e1a14 243 PANTHER PTHR12725 8 243 8.4E-29 T 23-04-2016 DC74_RS38025 78fdd9b9f98ee55c0c32fb5c931e1a14 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 12 23 1.6E-7 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS38025 78fdd9b9f98ee55c0c32fb5c931e1a14 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 173 193 1.6E-7 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS38025 78fdd9b9f98ee55c0c32fb5c931e1a14 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 171 1.6E-7 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS38025 78fdd9b9f98ee55c0c32fb5c931e1a14 243 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 105 211 4.0E-8 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS38025 78fdd9b9f98ee55c0c32fb5c931e1a14 243 Pfam PF13419 Haloacid dehalogenase-like hydrolase 106 210 7.9E-13 T 23-04-2016 IPR023214 HAD-like domain DC74_RS38025 78fdd9b9f98ee55c0c32fb5c931e1a14 243 Gene3D G3DSA:3.40.50.1000 12 220 9.6E-32 T 23-04-2016 IPR023214 HAD-like domain DC74_RS17180 3025f2c69f29d53659af9b56eac30dfe 358 SUPERFAMILY SSF49319 31 116 1.7E-7 T 23-04-2016 IPR027273 Neocarzinostatin-like DC74_RS17180 3025f2c69f29d53659af9b56eac30dfe 358 Gene3D G3DSA:2.60.40.230 31 100 5.4E-6 T 23-04-2016 IPR027273 Neocarzinostatin-like DC74_RS31395 5156475b22ac7fff32bfb1b03dc8309b 546 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 26 545 9.6E-250 T 23-04-2016 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 DC74_RS31395 5156475b22ac7fff32bfb1b03dc8309b 546 PANTHER PTHR21631 1 146 4.3E-257 T 23-04-2016 DC74_RS31395 5156475b22ac7fff32bfb1b03dc8309b 546 PANTHER PTHR21631 162 546 4.3E-257 T 23-04-2016 DC74_RS31395 5156475b22ac7fff32bfb1b03dc8309b 546 Gene3D G3DSA:3.20.20.360 75 418 1.1E-117 T 23-04-2016 DC74_RS31395 5156475b22ac7fff32bfb1b03dc8309b 546 PIRSF PIRSF001363 9 546 2.2E-239 T 23-04-2016 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 DC74_RS31395 5156475b22ac7fff32bfb1b03dc8309b 546 SUPERFAMILY SSF51645 22 545 1.18E-176 T 23-04-2016 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 DC74_RS31395 5156475b22ac7fff32bfb1b03dc8309b 546 Gene3D G3DSA:1.20.1220.12 422 539 4.8E-25 T 23-04-2016 DC74_RS31395 5156475b22ac7fff32bfb1b03dc8309b 546 PANTHER PTHR21631:SF1 1 146 4.3E-257 T 23-04-2016 DC74_RS31395 5156475b22ac7fff32bfb1b03dc8309b 546 PANTHER PTHR21631:SF1 162 546 4.3E-257 T 23-04-2016 DC74_RS31395 5156475b22ac7fff32bfb1b03dc8309b 546 Pfam PF01274 Malate synthase 21 546 7.5E-199 T 23-04-2016 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 DC74_RS31395 5156475b22ac7fff32bfb1b03dc8309b 546 ProSitePatterns PS00510 Malate synthase signature. 272 287 - T 23-04-2016 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 PANTHER PTHR24322:SF330 8 112 1.9E-16 T 23-04-2016 DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 PANTHER PTHR24322:SF330 153 186 1.9E-16 T 23-04-2016 DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 Gene3D G3DSA:3.40.50.720 4 249 6.1E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 166 0.0014 T 23-04-2016 DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 249 9.8E-22 T 23-04-2016 DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.2E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.2E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.2E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.2E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 63 74 1.2E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 PANTHER PTHR24322 8 112 1.9E-16 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 PANTHER PTHR24322 153 186 1.9E-16 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32955 5aac6615e35dd03cf3130594f1d7055f 259 SUPERFAMILY SSF51735 4 251 1.19E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS22945 1ee2cffb60c8ac25d258164d054b2240 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 2.9E-113 T 23-04-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 DC74_RS22945 1ee2cffb60c8ac25d258164d054b2240 258 Gene3D G3DSA:3.40.50.300 4 251 2.0E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22945 1ee2cffb60c8ac25d258164d054b2240 258 Pfam PF00005 ABC transporter 21 176 3.8E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS22945 1ee2cffb60c8ac25d258164d054b2240 258 SUPERFAMILY SSF52540 5 246 3.43E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22945 1ee2cffb60c8ac25d258164d054b2240 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS22945 1ee2cffb60c8ac25d258164d054b2240 258 SMART SM00382 29 229 7.9E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS22945 1ee2cffb60c8ac25d258164d054b2240 258 PANTHER PTHR24220:SF585 6 256 4.9E-127 T 23-04-2016 DC74_RS22945 1ee2cffb60c8ac25d258164d054b2240 258 PANTHER PTHR24220 6 256 4.9E-127 T 23-04-2016 DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 234 247 - T 23-04-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Reactome: REACT_13 DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 Gene3D G3DSA:2.40.37.10 244 258 8.1E-26 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 Gene3D G3DSA:2.40.37.10 315 475 8.1E-26 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 53 268 2.8E-27 T 23-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 89 101 7.4E-7 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 69 87 7.4E-7 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 337 356 7.4E-7 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 PANTHER PTHR11482 21 249 1.1E-31 T 23-04-2016 DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 PANTHER PTHR11482 320 449 1.1E-31 T 23-04-2016 DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 Gene3D G3DSA:3.20.20.10 45 243 1.0E-46 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 Gene3D G3DSA:3.20.20.10 301 314 1.0E-46 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 SUPERFAMILY SSF51419 36 253 4.07E-38 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 SUPERFAMILY SSF51419 301 349 4.07E-38 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS36715 c6865d0290862e18d533394f36e6fe5f 492 SUPERFAMILY SSF50621 334 466 4.19E-15 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS25780 8a884f6de9a9bb295c6739138e4d4060 265 PANTHER PTHR11921 17 265 1.9E-176 T 23-04-2016 DC74_RS25780 8a884f6de9a9bb295c6739138e4d4060 265 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 63 71 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS25780 8a884f6de9a9bb295c6739138e4d4060 265 PANTHER PTHR11921:SF10 17 265 1.9E-176 T 23-04-2016 DC74_RS25780 8a884f6de9a9bb295c6739138e4d4060 265 SUPERFAMILY SSF46548 133 235 2.44E-18 T 23-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 DC74_RS25780 8a884f6de9a9bb295c6739138e4d4060 265 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 26 234 6.1E-42 T 23-04-2016 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 DC74_RS25780 8a884f6de9a9bb295c6739138e4d4060 265 Gene3D G3DSA:3.10.20.30 9 113 7.0E-29 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS25780 8a884f6de9a9bb295c6739138e4d4060 265 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 17 115 9.2E-26 T 23-04-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 DC74_RS25780 8a884f6de9a9bb295c6739138e4d4060 265 Pfam PF13183 4Fe-4S dicluster domain 150 231 2.0E-14 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS25780 8a884f6de9a9bb295c6739138e4d4060 265 Gene3D G3DSA:1.10.1060.10 119 249 1.8E-18 T 23-04-2016 DC74_RS25780 8a884f6de9a9bb295c6739138e4d4060 265 SUPERFAMILY SSF54292 15 113 2.75E-22 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS03435 c4f22a642aeb84b0a58fb55379bf4888 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.8E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03435 c4f22a642aeb84b0a58fb55379bf4888 203 PANTHER PTHR30055 1 191 5.5E-24 T 23-04-2016 DC74_RS03435 c4f22a642aeb84b0a58fb55379bf4888 203 Gene3D G3DSA:1.10.357.10 8 195 1.8E-29 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS03435 c4f22a642aeb84b0a58fb55379bf4888 203 SUPERFAMILY SSF48498 89 189 3.11E-5 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS03435 c4f22a642aeb84b0a58fb55379bf4888 203 PANTHER PTHR30055:SF37 1 191 5.5E-24 T 23-04-2016 DC74_RS03435 c4f22a642aeb84b0a58fb55379bf4888 203 SUPERFAMILY SSF46689 8 78 5.64E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS13380 c45e69ee8ff84825487660dd309e5181 446 PANTHER PTHR30061 13 443 8.4E-47 T 23-04-2016 DC74_RS13380 c45e69ee8ff84825487660dd309e5181 446 Gene3D G3DSA:3.40.190.10 173 359 3.4E-29 T 23-04-2016 DC74_RS13380 c45e69ee8ff84825487660dd309e5181 446 SUPERFAMILY SSF53850 47 430 1.09E-50 T 23-04-2016 DC74_RS13380 c45e69ee8ff84825487660dd309e5181 446 PANTHER PTHR30061:SF25 13 443 8.4E-47 T 23-04-2016 DC74_RS13380 c45e69ee8ff84825487660dd309e5181 446 Pfam PF01547 Bacterial extracellular solute-binding protein 58 341 1.9E-23 T 23-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 DC74_RS13380 c45e69ee8ff84825487660dd309e5181 446 Gene3D G3DSA:3.40.190.10 45 172 6.4E-14 T 23-04-2016 DC74_RS05385 e80185ceecd329a3d159baf79ec4992c 512 Gene3D G3DSA:3.40.50.980 168 317 1.8E-23 T 23-04-2016 DC74_RS05385 e80185ceecd329a3d159baf79ec4992c 512 Gene3D G3DSA:2.30.38.10 327 401 4.3E-19 T 23-04-2016 DC74_RS05385 e80185ceecd329a3d159baf79ec4992c 512 SUPERFAMILY SSF56801 21 504 7.72E-121 T 23-04-2016 DC74_RS05385 e80185ceecd329a3d159baf79ec4992c 512 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 491 6.7E-18 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS05385 e80185ceecd329a3d159baf79ec4992c 512 Gene3D G3DSA:3.30.300.30 402 500 1.8E-33 T 23-04-2016 DC74_RS05385 e80185ceecd329a3d159baf79ec4992c 512 Pfam PF00501 AMP-binding enzyme 22 407 4.3E-70 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS05385 e80185ceecd329a3d159baf79ec4992c 512 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS05385 e80185ceecd329a3d159baf79ec4992c 512 PANTHER PTHR24095 28 504 8.7E-110 T 23-04-2016 DC74_RS05385 e80185ceecd329a3d159baf79ec4992c 512 Gene3D G3DSA:3.40.50.980 22 167 1.4E-25 T 23-04-2016 DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 SUPERFAMILY SSF52172 2 130 2.56E-28 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 PANTHER PTHR26402:SF151 2 212 9.4E-65 T 23-04-2016 DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 SUPERFAMILY SSF46894 141 212 4.08E-18 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 PANTHER PTHR26402 2 212 9.4E-65 T 23-04-2016 DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 Gene3D G3DSA:1.10.10.10 152 211 2.4E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 1.3E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 Gene3D G3DSA:3.40.50.2300 2 151 1.8E-33 T 23-04-2016 DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 Pfam PF00072 Response regulator receiver domain 4 114 4.5E-22 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 SMART SM00421 149 206 4.1E-20 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 SMART SM00448 2 114 2.0E-23 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 6.4E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 6.4E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS24000 14c50d7bd030b258da7cd97c523b8494 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 6.4E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS23860 fa2c8e19d473a484cf9beb88e192c25a 567 PANTHER PTHR13943:SF41 44 555 4.2E-251 T 23-04-2016 DC74_RS23860 fa2c8e19d473a484cf9beb88e192c25a 567 PANTHER PTHR13943 44 555 4.2E-251 T 23-04-2016 DC74_RS23860 fa2c8e19d473a484cf9beb88e192c25a 567 Pfam PF07287 Protein of unknown function (DUF1446) 10 343 1.2E-126 T 23-04-2016 IPR010839 Protein of unknown function DUF1446 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 PANTHER PTHR11374 1 396 2.6E-221 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 SUPERFAMILY SSF51735 1 197 1.1E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 Gene3D G3DSA:3.40.50.720 238 427 6.6E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 Gene3D G3DSA:1.20.5.100 207 236 5.2E-11 T 23-04-2016 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 191 2.8E-52 T 23-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 405 2.4E-113 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 PIRSF PIRSF500135 1 441 1.8E-211 T 23-04-2016 IPR028358 GDP-mannose 6-dehydrogenase GO:0042121|GO:0047919 KEGG: 00040+1.1.1.13|KEGG: 00051+1.1.1.132|KEGG: 00520+1.1.1.132|MetaCyc: PWY-6073|MetaCyc: PWY-6082|UniPathway: UPA00286 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 SUPERFAMILY SSF52413 310 430 9.68E-20 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 321 405 7.9E-10 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 SUPERFAMILY SSF48179 207 301 2.79E-25 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 SMART SM00984 320 427 2.8E-18 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 208 301 7.6E-28 T 23-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 PIRSF PIRSF000124 1 441 1.8E-130 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 PANTHER PTHR11374:SF22 1 396 2.6E-221 T 23-04-2016 DC74_RS05435 9d994681db7c8d7338333b284c68feec 441 Gene3D G3DSA:3.40.50.720 1 203 1.1E-67 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 Pfam PF01556 DnaJ C terminal domain 145 358 3.0E-35 T 23-04-2016 IPR002939 Chaperone DnaJ, C-terminal DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 SUPERFAMILY SSF49493 139 193 2.35E-20 T 23-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 SUPERFAMILY SSF49493 238 291 2.35E-20 T 23-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 SUPERFAMILY SSF57938 159 233 8.5E-13 T 23-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 Pfam PF00226 DnaJ domain 10 72 9.7E-26 T 23-04-2016 IPR001623 DnaJ domain DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 392 36.874 T 23-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 Gene3D G3DSA:2.10.230.10 167 234 4.5E-15 T 23-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 SUPERFAMILY SSF49493 284 369 6.02E-21 T 23-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 Gene3D G3DSA:2.60.260.20 235 278 8.8E-22 T 23-04-2016 DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 Gene3D G3DSA:2.60.260.20 120 166 8.8E-22 T 23-04-2016 DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 375 2.6E-120 T 23-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 PANTHER PTHR24078:SF255 1 384 8.9E-115 T 23-04-2016 DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 Gene3D G3DSA:2.60.260.20 281 359 1.9E-20 T 23-04-2016 DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 SMART SM00271 9 67 1.9E-28 T 23-04-2016 IPR001623 DnaJ domain DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 Pfam PF00684 DnaJ central domain 172 232 7.1E-9 T 23-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 ProSitePatterns PS00636 Nt-dnaJ domain signature. 52 71 - T 23-04-2016 IPR018253 DnaJ domain, conserved site DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 Gene3D G3DSA:1.10.287.110 4 93 5.7E-30 T 23-04-2016 IPR001623 DnaJ domain DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 PRINTS PR00625 DnaJ domain signature 12 30 2.4E-21 T 23-04-2016 IPR001623 DnaJ domain DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 PRINTS PR00625 DnaJ domain signature 67 86 2.4E-21 T 23-04-2016 IPR001623 DnaJ domain DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 PRINTS PR00625 DnaJ domain signature 30 45 2.4E-21 T 23-04-2016 IPR001623 DnaJ domain DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 PRINTS PR00625 DnaJ domain signature 47 67 2.4E-21 T 23-04-2016 IPR001623 DnaJ domain DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 SUPERFAMILY SSF46565 9 108 1.14E-29 T 23-04-2016 IPR001623 DnaJ domain DC74_RS19945 087a39d77ddb3bf32306f41f285f39ac 392 PANTHER PTHR24078 1 384 8.9E-115 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:3.30.300.30 902 1019 1.8E-38 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:3.30.300.30 3023 3141 1.4E-33 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:3.30.300.30 1959 2081 2.5E-37 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF47336 1009 1081 2.36E-18 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:3.40.50.980 1555 1714 2.5E-53 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:3.40.50.980 506 661 9.2E-44 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:3.40.50.980 2622 2793 2.2E-47 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF13193 AMP-binding enzyme C-terminal domain 914 989 1.2E-10 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF13193 AMP-binding enzyme C-terminal domain 3036 3109 1.1E-7 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF13193 AMP-binding enzyme C-terminal domain 1972 2052 9.2E-9 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF56801 471 1027 1.96E-147 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2772 2783 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF52777 2353 2614 2.67E-65 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF52777 1286 1526 3.0E-67 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF47336 3129 3200 1.16E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF00501 AMP-binding enzyme 2631 3028 1.8E-97 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF00501 AMP-binding enzyme 512 906 9.8E-90 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF00501 AMP-binding enzyme 1563 1964 1.0E-100 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1583 1988 4.7E-138 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 533 930 3.5E-123 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2650 3051 9.5E-136 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SMART SM00823 Phosphopantetheine attachment site 3135 3204 0.024 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SMART SM00823 Phosphopantetheine attachment site 1015 1084 8.3E-4 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SMART SM00823 Phosphopantetheine attachment site 2078 2147 4.0E-8 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:1.10.1200.10 1020 1084 1.2E-25 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:1.10.1200.10 3142 3201 1.2E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:1.10.1200.10 2082 2147 9.7E-29 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 PANTHER PTHR24095:SF137 680 3109 0.0 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:3.40.50.1820 3403 3473 5.1E-43 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:3.40.50.1820 3208 3324 5.1E-43 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF47336 2070 2144 6.94E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:2.30.38.10 818 896 4.1E-25 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:2.30.38.10 1876 1953 1.9E-27 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:2.30.38.10 2941 3017 3.0E-29 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SMART SM00824 Thioesterase 3232 3472 1.8E-5 T 23-04-2016 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF00668 Condensation domain 52 347 1.5E-72 T 23-04-2016 IPR001242 Condensation domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF00668 Condensation domain 2159 2462 7.2E-67 T 23-04-2016 IPR001242 Condensation domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF00668 Condensation domain 1098 1397 1.3E-67 T 23-04-2016 IPR001242 Condensation domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF53474 3208 3472 2.46E-52 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1039 1054 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2102 2117 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:3.40.50.980 662 817 9.6E-32 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:3.40.50.980 1715 1875 1.5E-39 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF00550 Phosphopantetheine attachment site 1017 1080 8.0E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF00550 Phosphopantetheine attachment site 2080 2143 3.2E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF00550 Phosphopantetheine attachment site 3139 3199 8.5E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Gene3D G3DSA:3.40.50.980 2794 2940 2.4E-37 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF56801 1523 2090 2.35E-157 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF52777 2164 2345 8.45E-47 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF00975 Thioesterase domain 3221 3459 1.7E-31 T 23-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF52777 235 500 2.22E-65 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF52777 53 229 2.0E-48 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF52777 1102 1279 1.89E-44 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF13745 HxxPF-repeated domain 1419 1509 1.8E-33 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF13745 HxxPF-repeated domain 370 459 5.1E-28 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 Pfam PF13745 HxxPF-repeated domain 2485 2575 3.4E-33 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 PANTHER PTHR24095 680 3109 0.0 T 23-04-2016 DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 ProSitePatterns PS00455 Putative AMP-binding domain signature. 653 664 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS04635 19fcda200f6405fa865081afcb709bf5 3475 SUPERFAMILY SSF56801 2588 3148 3.92E-152 T 23-04-2016 DC74_RS35280 01f8cf7af452309539692dc757826870 385 Gene3D G3DSA:3.30.420.40 84 225 2.1E-39 T 23-04-2016 DC74_RS35280 01f8cf7af452309539692dc757826870 385 Pfam PF00480 ROK family 89 367 4.3E-35 T 23-04-2016 IPR000600 ROK family DC74_RS35280 01f8cf7af452309539692dc757826870 385 SUPERFAMILY SSF53067 86 373 1.22E-45 T 23-04-2016 DC74_RS35280 01f8cf7af452309539692dc757826870 385 PANTHER PTHR18964:SF108 61 373 1.1E-82 T 23-04-2016 DC74_RS35280 01f8cf7af452309539692dc757826870 385 Gene3D G3DSA:1.10.10.10 11 81 8.3E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35280 01f8cf7af452309539692dc757826870 385 PANTHER PTHR18964 61 373 1.1E-82 T 23-04-2016 DC74_RS35280 01f8cf7af452309539692dc757826870 385 SUPERFAMILY SSF46785 12 80 3.57E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35280 01f8cf7af452309539692dc757826870 385 Pfam PF12802 MarR family 20 68 7.5E-7 T 23-04-2016 DC74_RS35280 01f8cf7af452309539692dc757826870 385 Gene3D G3DSA:3.30.420.40 226 351 3.2E-24 T 23-04-2016 DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 Gene3D G3DSA:3.40.140.20 372 513 1.9E-48 T 23-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 Gene3D G3DSA:3.40.140.20 249 366 5.8E-44 T 23-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 Pfam PF01808 AICARFT/IMPCHase bienzyme 142 456 7.2E-111 T 23-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 12 523 5.1E-170 T 23-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 Pfam PF02142 MGS-like domain 23 136 1.4E-23 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 PANTHER PTHR11692:SF2 9 523 5.2E-263 T 23-04-2016 DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 PANTHER PTHR11692 9 523 5.2E-263 T 23-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 SUPERFAMILY SSF52335 11 201 8.09E-63 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 SMART SM00851 23 137 1.2E-48 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 11 523 41.273 T 23-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 SMART SM00798 142 457 2.0E-179 T 23-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 Gene3D G3DSA:3.40.50.1380 9 192 9.3E-76 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 PIRSF PIRSF000414 5 523 2.3E-193 T 23-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 DC74_RS24555 1a5905797d0ccf8f00adb97ab5e92673 523 SUPERFAMILY SSF53927 219 523 8.42E-115 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS28120 7079a0250e5d4c3d740a8f3c3433f432 181 Pfam PF01782 RimM N-terminal domain 5 83 1.1E-22 T 23-04-2016 IPR002676 RimM protein GO:0006364 DC74_RS28120 7079a0250e5d4c3d740a8f3c3433f432 181 Pfam PF05239 PRC-barrel domain 94 166 7.7E-10 T 23-04-2016 IPR027275 PRC-barrel domain DC74_RS28120 7079a0250e5d4c3d740a8f3c3433f432 181 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 166 23.107 T 23-04-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 DC74_RS28120 7079a0250e5d4c3d740a8f3c3433f432 181 Gene3D G3DSA:2.30.30.240 96 166 5.2E-19 T 23-04-2016 DC74_RS28120 7079a0250e5d4c3d740a8f3c3433f432 181 PANTHER PTHR33692 3 181 7.3E-50 T 23-04-2016 DC74_RS28120 7079a0250e5d4c3d740a8f3c3433f432 181 Gene3D G3DSA:2.40.30.60 3 83 2.4E-21 T 23-04-2016 IPR002676 RimM protein GO:0006364 DC74_RS28120 7079a0250e5d4c3d740a8f3c3433f432 181 SUPERFAMILY SSF50447 3 84 1.59E-18 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS28120 7079a0250e5d4c3d740a8f3c3433f432 181 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 166 5.9E-42 T 23-04-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 DC74_RS28120 7079a0250e5d4c3d740a8f3c3433f432 181 SUPERFAMILY SSF50346 96 166 1.04E-17 T 23-04-2016 IPR011033 PRC-barrel-like DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 Gene3D G3DSA:1.20.120.620 408 505 7.8E-12 T 23-04-2016 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 SUPERFAMILY SSF52402 245 360 3.77E-5 T 23-04-2016 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 Gene3D G3DSA:3.30.565.10 712 881 1.7E-36 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 SUPERFAMILY SSF55874 714 883 4.71E-37 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 Pfam PF00512 His Kinase A (phospho-acceptor) domain 658 725 2.8E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 SUPERFAMILY SSF47384 649 725 1.02E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 Gene3D G3DSA:3.40.50.300 16 222 2.8E-89 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 SMART SM00388 657 725 4.1E-12 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 Pfam PF00582 Universal stress protein family 244 370 7.0E-5 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 772 879 7.8E-17 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 Pfam PF13493 Domain of unknown function (DUF4118) 411 515 8.1E-16 T 23-04-2016 IPR025201 Sensor protein KdpD, transmembrane domain DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 SMART SM00387 771 881 1.4E-28 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 17 224 4.0E-89 T 23-04-2016 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 Gene3D G3DSA:3.40.50.620 240 380 4.8E-7 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 PANTHER PTHR24423 17 191 2.7E-108 T 23-04-2016 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 PANTHER PTHR24423 597 878 2.7E-108 T 23-04-2016 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 PANTHER PTHR24423:SF562 17 191 2.7E-108 T 23-04-2016 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 PANTHER PTHR24423:SF562 597 878 2.7E-108 T 23-04-2016 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 808 822 8.8E-10 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 841 859 8.8E-10 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 826 836 8.8E-10 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 865 878 8.8E-10 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS37970 5d5bd0e4d700fda6665e0d29fa147125 917 Gene3D G3DSA:1.10.287.130 651 711 3.3E-14 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS02340 01de8e96b42af0a899d25e0974bd150b 260 Gene3D G3DSA:3.40.1080.10 3 232 3.0E-96 T 23-04-2016 DC74_RS02340 01de8e96b42af0a899d25e0974bd150b 260 Pfam PF01144 Coenzyme A transferase 7 233 5.2E-69 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 DC74_RS02340 01de8e96b42af0a899d25e0974bd150b 260 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 17 32 - T 23-04-2016 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 DC74_RS02340 01de8e96b42af0a899d25e0974bd150b 260 SMART SM00882 5 234 6.4E-80 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 DC74_RS02340 01de8e96b42af0a899d25e0974bd150b 260 PANTHER PTHR13707 1 249 1.8E-126 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 DC74_RS02340 01de8e96b42af0a899d25e0974bd150b 260 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 139 6.2E-40 T 23-04-2016 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 DC74_RS02340 01de8e96b42af0a899d25e0974bd150b 260 SUPERFAMILY SSF100950 2 237 7.67E-83 T 23-04-2016 DC74_RS27165 472f0aabc85d0bc3380d5c917f635187 158 Gene3D G3DSA:1.10.10.10 3 154 1.3E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27165 472f0aabc85d0bc3380d5c917f635187 158 PANTHER PTHR33164:SF1 9 158 5.4E-47 T 23-04-2016 DC74_RS27165 472f0aabc85d0bc3380d5c917f635187 158 PANTHER PTHR33164 9 158 5.4E-47 T 23-04-2016 DC74_RS27165 472f0aabc85d0bc3380d5c917f635187 158 SMART SM00347 34 137 5.4E-15 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS27165 472f0aabc85d0bc3380d5c917f635187 158 Pfam PF12802 MarR family 40 100 2.0E-11 T 23-04-2016 DC74_RS27165 472f0aabc85d0bc3380d5c917f635187 158 SUPERFAMILY SSF46785 5 151 1.34E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05880 dee7565d45724f353ed61a2ccb121e97 158 Gene3D G3DSA:1.10.150.120 77 155 3.0E-23 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS05880 dee7565d45724f353ed61a2ccb121e97 158 PANTHER PTHR11908:SF66 3 141 8.7E-15 T 23-04-2016 DC74_RS05880 dee7565d45724f353ed61a2ccb121e97 158 SUPERFAMILY SSF54292 4 81 6.69E-21 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS05880 dee7565d45724f353ed61a2ccb121e97 158 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 55 3.0E-7 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS05880 dee7565d45724f353ed61a2ccb121e97 158 Pfam PF01799 [2Fe-2S] binding domain 75 151 3.2E-22 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS05880 dee7565d45724f353ed61a2ccb121e97 158 Gene3D G3DSA:3.10.20.30 4 76 3.7E-21 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS05880 dee7565d45724f353ed61a2ccb121e97 158 PANTHER PTHR11908 3 141 8.7E-15 T 23-04-2016 DC74_RS05880 dee7565d45724f353ed61a2ccb121e97 158 SUPERFAMILY SSF47741 88 156 2.49E-24 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS06450 bb547fde43226a853f69c757e025591b 324 Gene3D G3DSA:3.30.470.20 190 284 2.1E-21 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS06450 bb547fde43226a853f69c757e025591b 324 Pfam PF08443 RimK-like ATP-grasp domain 114 284 4.3E-30 T 23-04-2016 IPR013651 ATP-grasp fold, RimK-type DC74_RS06450 bb547fde43226a853f69c757e025591b 324 PANTHER PTHR21621 1 284 2.3E-62 T 23-04-2016 DC74_RS06450 bb547fde43226a853f69c757e025591b 324 SUPERFAMILY SSF56059 104 299 5.77E-29 T 23-04-2016 DC74_RS06450 bb547fde43226a853f69c757e025591b 324 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 68 285 2.6E-50 T 23-04-2016 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 DC74_RS06450 bb547fde43226a853f69c757e025591b 324 Gene3D G3DSA:3.40.50.20 24 118 2.8E-19 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS06450 bb547fde43226a853f69c757e025591b 324 Gene3D G3DSA:3.30.1490.20 119 189 7.2E-6 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS01500 88470ca0b67c951012568f735c7aa5a2 285 SUPERFAMILY SSF53850 88 284 3.74E-37 T 23-04-2016 DC74_RS01500 88470ca0b67c951012568f735c7aa5a2 285 PANTHER PTHR30346 1 283 2.4E-75 T 23-04-2016 DC74_RS01500 88470ca0b67c951012568f735c7aa5a2 285 Gene3D G3DSA:3.40.190.10 90 178 1.3E-18 T 23-04-2016 DC74_RS01500 88470ca0b67c951012568f735c7aa5a2 285 Pfam PF03466 LysR substrate binding domain 87 283 3.8E-39 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS01500 88470ca0b67c951012568f735c7aa5a2 285 Gene3D G3DSA:1.10.10.10 1 83 2.4E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01500 88470ca0b67c951012568f735c7aa5a2 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.1E-23 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS01500 88470ca0b67c951012568f735c7aa5a2 285 SUPERFAMILY SSF46785 1 86 1.63E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01500 88470ca0b67c951012568f735c7aa5a2 285 Gene3D G3DSA:3.40.190.10 179 263 1.6E-20 T 23-04-2016 DC74_RS01500 88470ca0b67c951012568f735c7aa5a2 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.5E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS01500 88470ca0b67c951012568f735c7aa5a2 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.5E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS01500 88470ca0b67c951012568f735c7aa5a2 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.5E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS09545 f8f6459f941ce18cc046e54ea3c08d2a 203 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 5 203 1.8E-61 T 23-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 DC74_RS09545 f8f6459f941ce18cc046e54ea3c08d2a 203 PANTHER PTHR11831 2 203 8.1E-60 T 23-04-2016 IPR022801 Ribosomal protein S4/S9 DC74_RS09545 f8f6459f941ce18cc046e54ea3c08d2a 203 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 5 90 7.1E-18 T 23-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 DC74_RS09545 f8f6459f941ce18cc046e54ea3c08d2a 203 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 23-04-2016 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 DC74_RS09545 f8f6459f941ce18cc046e54ea3c08d2a 203 PANTHER PTHR11831:SF4 2 203 8.1E-60 T 23-04-2016 DC74_RS09545 f8f6459f941ce18cc046e54ea3c08d2a 203 SUPERFAMILY SSF55174 5 203 1.96E-55 T 23-04-2016 DC74_RS09545 f8f6459f941ce18cc046e54ea3c08d2a 203 Pfam PF01479 S4 domain 91 138 1.1E-17 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS09545 f8f6459f941ce18cc046e54ea3c08d2a 203 SMART SM01390 2 90 7.2E-33 T 23-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 DC74_RS09545 f8f6459f941ce18cc046e54ea3c08d2a 203 Gene3D G3DSA:1.10.1050.10 4 96 4.0E-27 T 23-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 DC74_RS09545 f8f6459f941ce18cc046e54ea3c08d2a 203 SMART SM00363 91 157 2.2E-15 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS09545 f8f6459f941ce18cc046e54ea3c08d2a 203 Gene3D G3DSA:3.10.290.10 97 187 3.6E-24 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS09545 f8f6459f941ce18cc046e54ea3c08d2a 203 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 203 29.137 T 23-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 630 29.561 T 23-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 Gene3D G3DSA:3.30.565.10 4 241 6.0E-75 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 SUPERFAMILY SSF54211 234 487 7.21E-89 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 SMART SM00387 26 183 6.2E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 49 156 3.5E-12 T 23-04-2016 DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 PIRSF PIRSF002583 1 633 2.7E-203 T 23-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 Pfam PF00183 Hsp90 protein 227 629 9.4E-123 T 23-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 PANTHER PTHR11528 2 623 9.7E-295 T 23-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 24 33 - T 23-04-2016 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 SUPERFAMILY SSF55874 3 217 2.23E-58 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 PRINTS PR00775 90kDa heat shock protein signature 74 91 6.9E-54 T 23-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 PRINTS PR00775 90kDa heat shock protein signature 4 24 6.9E-54 T 23-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 PRINTS PR00775 90kDa heat shock protein signature 194 212 6.9E-54 T 23-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 PRINTS PR00775 90kDa heat shock protein signature 171 188 6.9E-54 T 23-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 PRINTS PR00775 90kDa heat shock protein signature 121 143 6.9E-54 T 23-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 PRINTS PR00775 90kDa heat shock protein signature 92 109 6.9E-54 T 23-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 PRINTS PR00775 90kDa heat shock protein signature 25 47 6.9E-54 T 23-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 SUPERFAMILY SSF110942 514 629 1.02E-29 T 23-04-2016 DC74_RS02630 18879e6ea1c6c78b701e81e1b3516de3 633 PANTHER PTHR11528:SF44 2 623 9.7E-295 T 23-04-2016 DC74_RS15165 8fbe9861b14f67521ed8c1985204608c 203 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 10 200 29.988 T 23-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 DC74_RS15165 8fbe9861b14f67521ed8c1985204608c 203 PANTHER PTHR12039 10 202 9.6E-54 T 23-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 DC74_RS15165 8fbe9861b14f67521ed8c1985204608c 203 Pfam PF01467 Cytidylyltransferase-like 14 174 1.4E-29 T 23-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DC74_RS15165 8fbe9861b14f67521ed8c1985204608c 203 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 76 8.7E-11 T 23-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DC74_RS15165 8fbe9861b14f67521ed8c1985204608c 203 Gene3D G3DSA:3.40.50.620 10 202 6.5E-66 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS15165 8fbe9861b14f67521ed8c1985204608c 203 SUPERFAMILY SSF52374 10 202 4.07E-53 T 23-04-2016 DC74_RS15165 8fbe9861b14f67521ed8c1985204608c 203 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 14 199 6.8E-55 T 23-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 1.4E-73 T 23-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 SUPERFAMILY SSF56053 1 83 5.37E-26 T 23-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 Pfam PF00347 Ribosomal protein L6 11 83 2.1E-19 T 23-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 Pfam PF00347 Ribosomal protein L6 92 165 9.1E-20 T 23-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 PIRSF PIRSF002162 1 178 8.2E-49 T 23-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 PANTHER PTHR11655:SF14 1 179 3.7E-87 T 23-04-2016 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 Gene3D G3DSA:3.90.930.12 84 178 3.3E-38 T 23-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 Gene3D G3DSA:3.90.930.12 2 83 1.2E-29 T 23-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 23-04-2016 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.383 T 23-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 SUPERFAMILY SSF56053 84 177 2.22E-35 T 23-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 PANTHER PTHR11655 1 179 3.7E-87 T 23-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 2.1E-32 T 23-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 2.1E-32 T 23-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS18665 e83b2efbcea5a7c30ddd354f3af4996f 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 2.1E-32 T 23-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS15015 93671d8c3d4eea243de1084812d41f28 250 Pfam PF03803 Scramblase 53 240 7.4E-7 T 23-04-2016 IPR005552 Scramblase DC74_RS15015 93671d8c3d4eea243de1084812d41f28 250 SUPERFAMILY SSF54518 103 224 3.14E-8 T 23-04-2016 IPR025659 Tubby C-terminal-like domain DC74_RS23785 8c20a5baf43e3776750668feea0705b9 452 PANTHER PTHR23513 9 438 3.3E-144 T 23-04-2016 DC74_RS23785 8c20a5baf43e3776750668feea0705b9 452 Pfam PF05977 Transmembrane secretion effector 19 409 7.2E-55 T 23-04-2016 IPR010290 Transmembrane secretion effector DC74_RS23785 8c20a5baf43e3776750668feea0705b9 452 Gene3D G3DSA:1.20.1250.20 31 210 1.4E-17 T 23-04-2016 DC74_RS23785 8c20a5baf43e3776750668feea0705b9 452 Gene3D G3DSA:1.20.1250.20 234 411 1.0E-12 T 23-04-2016 DC74_RS23785 8c20a5baf43e3776750668feea0705b9 452 SUPERFAMILY SSF103473 27 411 3.27E-46 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS23785 8c20a5baf43e3776750668feea0705b9 452 PANTHER PTHR23513:SF6 9 438 3.3E-144 T 23-04-2016 DC74_RS17770 548953db7e5a3c251e5c16ac83df47d0 312 Pfam PF00005 ABC transporter 24 160 2.1E-25 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS17770 548953db7e5a3c251e5c16ac83df47d0 312 SUPERFAMILY SSF52540 8 222 4.14E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17770 548953db7e5a3c251e5c16ac83df47d0 312 SMART SM00382 33 217 1.0E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS17770 548953db7e5a3c251e5c16ac83df47d0 312 PANTHER PTHR24220 262 289 1.5E-66 T 23-04-2016 DC74_RS17770 548953db7e5a3c251e5c16ac83df47d0 312 PANTHER PTHR24220 10 239 1.5E-66 T 23-04-2016 DC74_RS17770 548953db7e5a3c251e5c16ac83df47d0 312 Gene3D G3DSA:3.40.50.300 4 222 1.7E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17770 548953db7e5a3c251e5c16ac83df47d0 312 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS02425 2cbe25881b85388059d85e0065872e02 260 SUPERFAMILY SSF52540 19 235 1.16E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02425 2cbe25881b85388059d85e0065872e02 260 SMART SM00382 45 231 4.0E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS02425 2cbe25881b85388059d85e0065872e02 260 Pfam PF00005 ABC transporter 36 182 2.4E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS02425 2cbe25881b85388059d85e0065872e02 260 PANTHER PTHR24220 18 254 5.2E-145 T 23-04-2016 DC74_RS02425 2cbe25881b85388059d85e0065872e02 260 PANTHER PTHR24220:SF484 18 254 5.2E-145 T 23-04-2016 DC74_RS02425 2cbe25881b85388059d85e0065872e02 260 Gene3D G3DSA:3.40.50.300 18 235 8.1E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02425 2cbe25881b85388059d85e0065872e02 260 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS15555 744cfbc5a2c2171af6018dc10028f4b6 457 SMART SM00332 182 445 3.7E-8 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS15555 744cfbc5a2c2171af6018dc10028f4b6 457 SUPERFAMILY SSF81606 193 447 3.27E-39 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS15555 744cfbc5a2c2171af6018dc10028f4b6 457 Gene3D G3DSA:3.60.40.10 193 447 7.2E-51 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS15555 744cfbc5a2c2171af6018dc10028f4b6 457 Pfam PF13672 Protein phosphatase 2C 200 402 2.1E-13 T 23-04-2016 DC74_RS15555 744cfbc5a2c2171af6018dc10028f4b6 457 SMART SM00331 203 447 0.0016 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS15555 744cfbc5a2c2171af6018dc10028f4b6 457 PANTHER PTHR10994 177 361 1.6E-21 T 23-04-2016 DC74_RS15555 744cfbc5a2c2171af6018dc10028f4b6 457 PANTHER PTHR10994:SF7 177 361 1.6E-21 T 23-04-2016 DC74_RS27540 be2ce78226bb50ef0387d06ffd7c1b02 383 PANTHER PTHR11933:SF10 8 371 3.2E-159 T 23-04-2016 DC74_RS27540 be2ce78226bb50ef0387d06ffd7c1b02 383 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 12 365 4.8E-88 T 23-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 DC74_RS27540 be2ce78226bb50ef0387d06ffd7c1b02 383 Gene3D G3DSA:2.40.30.10 291 369 5.0E-20 T 23-04-2016 DC74_RS27540 be2ce78226bb50ef0387d06ffd7c1b02 383 Pfam PF03054 tRNA methyl transferase 11 365 1.7E-118 T 23-04-2016 DC74_RS27540 be2ce78226bb50ef0387d06ffd7c1b02 383 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 10 366 36.604 T 23-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 DC74_RS27540 be2ce78226bb50ef0387d06ffd7c1b02 383 PANTHER PTHR11933 8 371 3.2E-159 T 23-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 DC74_RS27540 be2ce78226bb50ef0387d06ffd7c1b02 383 Gene3D G3DSA:2.30.30.280 224 285 1.0E-16 T 23-04-2016 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 DC74_RS27540 be2ce78226bb50ef0387d06ffd7c1b02 383 SUPERFAMILY SSF52402 11 254 1.32E-46 T 23-04-2016 DC74_RS27540 be2ce78226bb50ef0387d06ffd7c1b02 383 Gene3D G3DSA:3.40.50.620 7 221 3.4E-76 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS36200 b49851d5e7ee2cadae05b7b27f396bb0 168 PANTHER PTHR30007 1 158 2.2E-46 T 23-04-2016 DC74_RS36200 b49851d5e7ee2cadae05b7b27f396bb0 168 Pfam PF13586 Transposase DDE domain 62 158 6.9E-17 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS36200 b49851d5e7ee2cadae05b7b27f396bb0 168 PANTHER PTHR30007:SF22 1 158 2.2E-46 T 23-04-2016 DC74_RS04370 b49851d5e7ee2cadae05b7b27f396bb0 168 PANTHER PTHR30007 1 158 2.2E-46 T 23-04-2016 DC74_RS04370 b49851d5e7ee2cadae05b7b27f396bb0 168 Pfam PF13586 Transposase DDE domain 62 158 6.9E-17 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS04370 b49851d5e7ee2cadae05b7b27f396bb0 168 PANTHER PTHR30007:SF22 1 158 2.2E-46 T 23-04-2016 DC74_RS02400 e8580c32894f43b4400e1743cbfd8569 229 Gene3D G3DSA:1.10.357.10 6 218 1.0E-53 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS02400 e8580c32894f43b4400e1743cbfd8569 229 PRINTS PR00400 Tetracycline repressor protein signature 83 102 3.9E-10 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS02400 e8580c32894f43b4400e1743cbfd8569 229 PRINTS PR00400 Tetracycline repressor protein signature 200 214 3.9E-10 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS02400 e8580c32894f43b4400e1743cbfd8569 229 PRINTS PR00400 Tetracycline repressor protein signature 31 54 3.9E-10 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS02400 e8580c32894f43b4400e1743cbfd8569 229 SUPERFAMILY SSF46689 14 73 2.57E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02400 e8580c32894f43b4400e1743cbfd8569 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 63 4.8E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS02400 e8580c32894f43b4400e1743cbfd8569 229 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 75 217 9.8E-17 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS02400 e8580c32894f43b4400e1743cbfd8569 229 PANTHER PTHR30055:SF36 2 132 3.8E-24 T 23-04-2016 DC74_RS02400 e8580c32894f43b4400e1743cbfd8569 229 PANTHER PTHR30055 2 132 3.8E-24 T 23-04-2016 DC74_RS02400 e8580c32894f43b4400e1743cbfd8569 229 SUPERFAMILY SSF48498 81 217 3.41E-24 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS11400 bfb366f815ff42148942dc277e09753b 265 Gene3D G3DSA:2.40.400.10 30 252 7.0E-52 T 23-04-2016 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 DC74_RS11400 bfb366f815ff42148942dc277e09753b 265 Pfam PF06314 Acetoacetate decarboxylase (ADC) 17 225 5.8E-45 T 23-04-2016 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 DC74_RS11400 bfb366f815ff42148942dc277e09753b 265 SUPERFAMILY SSF160104 27 224 4.45E-42 T 23-04-2016 DC74_RS22540 c79b72637fa7557e784d8944dfdf7581 369 SMART SM00418 287 365 8.1E-22 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS22540 c79b72637fa7557e784d8944dfdf7581 369 Pfam PF12840 Helix-turn-helix domain 286 345 5.2E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22540 c79b72637fa7557e784d8944dfdf7581 369 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 321 336 1.6E-8 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS22540 c79b72637fa7557e784d8944dfdf7581 369 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 336 351 1.6E-8 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS22540 c79b72637fa7557e784d8944dfdf7581 369 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 289 304 1.6E-8 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS22540 c79b72637fa7557e784d8944dfdf7581 369 PANTHER PTHR33154:SF11 26 369 4.6E-135 T 23-04-2016 DC74_RS22540 c79b72637fa7557e784d8944dfdf7581 369 SUPERFAMILY SSF46785 282 360 1.43E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22540 c79b72637fa7557e784d8944dfdf7581 369 PANTHER PTHR33154 26 369 4.6E-135 T 23-04-2016 DC74_RS22540 c79b72637fa7557e784d8944dfdf7581 369 Gene3D G3DSA:1.10.10.10 280 364 2.0E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04560 5d4c238495f2682ef5301d099397d65a 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 68 2.3E-15 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS04560 5d4c238495f2682ef5301d099397d65a 319 PANTHER PTHR30126 8 313 4.8E-80 T 23-04-2016 DC74_RS04560 5d4c238495f2682ef5301d099397d65a 319 Gene3D G3DSA:3.40.190.10 99 183 1.4E-19 T 23-04-2016 DC74_RS04560 5d4c238495f2682ef5301d099397d65a 319 Gene3D G3DSA:3.40.190.10 184 270 8.2E-22 T 23-04-2016 DC74_RS04560 5d4c238495f2682ef5301d099397d65a 319 Gene3D G3DSA:1.10.10.10 9 92 1.5E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04560 5d4c238495f2682ef5301d099397d65a 319 SUPERFAMILY SSF46785 7 117 5.44E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04560 5d4c238495f2682ef5301d099397d65a 319 SUPERFAMILY SSF53850 99 301 2.61E-37 T 23-04-2016 DC74_RS04560 5d4c238495f2682ef5301d099397d65a 319 PANTHER PTHR30126:SF11 8 313 4.8E-80 T 23-04-2016 DC74_RS04560 5d4c238495f2682ef5301d099397d65a 319 Pfam PF03466 LysR substrate binding domain 97 301 5.4E-44 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS15010 84419adab46e4b0cc0e88d03483ace4a 143 Pfam PF02566 OsmC-like protein 44 132 4.0E-19 T 23-04-2016 IPR003718 OsmC/Ohr family DC74_RS15010 84419adab46e4b0cc0e88d03483ace4a 143 PANTHER PTHR33797 1 143 2.8E-47 T 23-04-2016 DC74_RS15010 84419adab46e4b0cc0e88d03483ace4a 143 Gene3D G3DSA:3.30.300.20 4 141 2.0E-43 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta DC74_RS15010 84419adab46e4b0cc0e88d03483ace4a 143 SUPERFAMILY SSF82784 4 139 1.11E-32 T 23-04-2016 IPR003718 OsmC/Ohr family DC74_RS15010 84419adab46e4b0cc0e88d03483ace4a 143 PANTHER PTHR33797:SF1 1 143 2.8E-47 T 23-04-2016 DC74_RS15010 84419adab46e4b0cc0e88d03483ace4a 143 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 138 1.3E-49 T 23-04-2016 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 DC74_RS34935 07e4ece05c38d97012277211ff060eaa 304 SUPERFAMILY SSF161098 70 294 1.14E-52 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS34935 07e4ece05c38d97012277211ff060eaa 304 Gene3D G3DSA:1.10.3720.10 74 301 2.3E-53 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS34935 07e4ece05c38d97012277211ff060eaa 304 PANTHER PTHR30193 1 304 3.2E-119 T 23-04-2016 DC74_RS34935 07e4ece05c38d97012277211ff060eaa 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 295 1.8E-11 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS34935 07e4ece05c38d97012277211ff060eaa 304 Gene3D G3DSA:1.20.58.370 25 56 9.7E-5 T 23-04-2016 DC74_RS34935 07e4ece05c38d97012277211ff060eaa 304 SUPERFAMILY SSF160964 25 63 6.41E-6 T 23-04-2016 DC74_RS34935 07e4ece05c38d97012277211ff060eaa 304 PANTHER PTHR30193:SF2 1 304 3.2E-119 T 23-04-2016 DC74_RS37070 4c2d833a1d9c185f42a628032eb41535 127 Pfam PF07977 FabA-like domain 15 108 1.2E-5 T 23-04-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 DC74_RS37070 4c2d833a1d9c185f42a628032eb41535 127 SUPERFAMILY SSF54637 7 111 2.85E-11 T 23-04-2016 IPR029069 HotDog domain DC74_RS37070 4c2d833a1d9c185f42a628032eb41535 127 Gene3D G3DSA:3.10.129.10 9 111 5.0E-12 T 23-04-2016 IPR029069 HotDog domain DC74_RS27635 de9c68ddb9d8879d0b1ed12eec728f77 705 Pfam PF05506 Domain of unknown function (DUF756) 619 695 1.0E-13 T 23-04-2016 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 DC74_RS27635 de9c68ddb9d8879d0b1ed12eec728f77 705 Pfam PF05506 Domain of unknown function (DUF756) 521 604 9.8E-17 T 23-04-2016 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 DC74_RS27635 de9c68ddb9d8879d0b1ed12eec728f77 705 Pfam PF04185 Phosphoesterase family 53 458 1.8E-98 T 23-04-2016 IPR007312 Phosphoesterase GO:0016788 DC74_RS27635 de9c68ddb9d8879d0b1ed12eec728f77 705 PANTHER PTHR31956:SF6 6 299 1.6E-118 T 23-04-2016 DC74_RS27635 de9c68ddb9d8879d0b1ed12eec728f77 705 PANTHER PTHR31956:SF6 327 528 1.6E-118 T 23-04-2016 DC74_RS27635 de9c68ddb9d8879d0b1ed12eec728f77 705 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 6 704 6.1E-220 T 23-04-2016 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 DC74_RS27635 de9c68ddb9d8879d0b1ed12eec728f77 705 PANTHER PTHR31956 6 299 1.6E-118 T 23-04-2016 DC74_RS27635 de9c68ddb9d8879d0b1ed12eec728f77 705 PANTHER PTHR31956 327 528 1.6E-118 T 23-04-2016 DC74_RS40505 9f476932ca2632ac795781310b5ee712 657 Gene3D G3DSA:3.40.47.10 287 464 1.1E-58 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40505 9f476932ca2632ac795781310b5ee712 657 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 403 523 1.6E-15 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS40505 9f476932ca2632ac795781310b5ee712 657 PANTHER PTHR11712:SF288 26 498 4.5E-194 T 23-04-2016 DC74_RS40505 9f476932ca2632ac795781310b5ee712 657 SMART SM00825 Beta-ketoacyl synthase 28 463 1.1E-193 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS40505 9f476932ca2632ac795781310b5ee712 657 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 187 203 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS40505 9f476932ca2632ac795781310b5ee712 657 SUPERFAMILY SSF53901 24 393 1.69E-93 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40505 9f476932ca2632ac795781310b5ee712 657 SUPERFAMILY SSF53901 439 458 1.69E-93 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40505 9f476932ca2632ac795781310b5ee712 657 PANTHER PTHR11712 26 498 4.5E-194 T 23-04-2016 DC74_RS40505 9f476932ca2632ac795781310b5ee712 657 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 26 274 9.4E-86 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS40505 9f476932ca2632ac795781310b5ee712 657 Gene3D G3DSA:3.40.47.10 28 286 7.4E-90 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40505 9f476932ca2632ac795781310b5ee712 657 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 282 399 7.5E-42 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS32075 edd4bb36ad27e75d85a83dd13f7253ad 467 PANTHER PTHR11360 51 444 2.4E-60 T 23-04-2016 DC74_RS32075 edd4bb36ad27e75d85a83dd13f7253ad 467 Gene3D G3DSA:1.20.1250.20 44 228 1.3E-15 T 23-04-2016 DC74_RS32075 edd4bb36ad27e75d85a83dd13f7253ad 467 PANTHER PTHR11360:SF3 51 444 2.4E-60 T 23-04-2016 DC74_RS32075 edd4bb36ad27e75d85a83dd13f7253ad 467 SUPERFAMILY SSF103473 35 452 1.96E-52 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS32075 edd4bb36ad27e75d85a83dd13f7253ad 467 Pfam PF07690 Major Facilitator Superfamily 50 352 7.9E-25 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS32075 edd4bb36ad27e75d85a83dd13f7253ad 467 Gene3D G3DSA:1.20.1250.20 271 452 1.5E-23 T 23-04-2016 DC74_RS05955 26dc81e115bf5bbcf4fba2a98d472df2 247 PANTHER PTHR10108 4 205 9.1E-20 T 23-04-2016 DC74_RS05955 26dc81e115bf5bbcf4fba2a98d472df2 247 SUPERFAMILY SSF53335 23 242 1.05E-35 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS05955 26dc81e115bf5bbcf4fba2a98d472df2 247 PANTHER PTHR10108:SF705 4 205 9.1E-20 T 23-04-2016 DC74_RS05955 26dc81e115bf5bbcf4fba2a98d472df2 247 Gene3D G3DSA:3.40.50.150 19 242 2.1E-38 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS05955 26dc81e115bf5bbcf4fba2a98d472df2 247 Pfam PF13847 Methyltransferase domain 36 142 3.5E-16 T 23-04-2016 IPR025714 Methyltransferase domain DC74_RS19930 91bea643e332c330732544fbdf726045 190 Pfam PF05685 Putative restriction endonuclease 17 184 9.3E-18 T 23-04-2016 IPR008538 Domain of unknown function DUF820 DC74_RS19930 91bea643e332c330732544fbdf726045 190 PANTHER PTHR35400:SF1 23 190 1.3E-25 T 23-04-2016 DC74_RS19930 91bea643e332c330732544fbdf726045 190 SUPERFAMILY SSF52980 9 170 1.18E-13 T 23-04-2016 IPR011335 Restriction endonuclease type II-like DC74_RS19930 91bea643e332c330732544fbdf726045 190 PANTHER PTHR35400 23 190 1.3E-25 T 23-04-2016 DC74_RS19930 91bea643e332c330732544fbdf726045 190 Gene3D G3DSA:3.90.1570.10 10 170 7.0E-13 T 23-04-2016 IPR012296 Nuclease, putative, TT1808 DC74_RS07435 3385166c54d660c8f26eae31a97523a6 370 PANTHER PTHR12526:SF353 125 368 2.3E-41 T 23-04-2016 DC74_RS07435 3385166c54d660c8f26eae31a97523a6 370 PANTHER PTHR12526 125 368 2.3E-41 T 23-04-2016 DC74_RS07435 3385166c54d660c8f26eae31a97523a6 370 SUPERFAMILY SSF53756 26 363 3.61E-51 T 23-04-2016 DC74_RS07435 3385166c54d660c8f26eae31a97523a6 370 Gene3D G3DSA:3.40.50.2000 183 340 1.7E-24 T 23-04-2016 DC74_RS07435 3385166c54d660c8f26eae31a97523a6 370 Pfam PF00534 Glycosyl transferases group 1 183 340 3.2E-25 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 DC74_RS01935 9f26cbc631588eb0093d6d1deb27fc87 485 ProSitePatterns PS00885 EPSP synthase signature 2. 389 407 - T 23-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS01935 9f26cbc631588eb0093d6d1deb27fc87 485 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 41 470 4.1E-67 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 DC74_RS01935 9f26cbc631588eb0093d6d1deb27fc87 485 Gene3D G3DSA:3.65.10.10 276 477 1.9E-38 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 DC74_RS01935 9f26cbc631588eb0093d6d1deb27fc87 485 PANTHER PTHR21090 41 485 1.6E-98 T 23-04-2016 DC74_RS01935 9f26cbc631588eb0093d6d1deb27fc87 485 SUPERFAMILY SSF55205 40 477 1.5E-82 T 23-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 DC74_RS01935 9f26cbc631588eb0093d6d1deb27fc87 485 PANTHER PTHR21090:SF5 41 485 1.6E-98 T 23-04-2016 DC74_RS01935 9f26cbc631588eb0093d6d1deb27fc87 485 Gene3D G3DSA:3.65.10.10 48 275 1.9E-34 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 DC74_RS01935 9f26cbc631588eb0093d6d1deb27fc87 485 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 36 478 24.387 T 23-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS01935 9f26cbc631588eb0093d6d1deb27fc87 485 PIRSF PIRSF000505 31 482 1.7E-80 T 23-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 Pfam PF02056 Family 4 glycosyl hydrolase 5 176 3.3E-40 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 PANTHER PTHR32092 329 441 1.0E-127 T 23-04-2016 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 PANTHER PTHR32092 1 309 1.0E-127 T 23-04-2016 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 429 9.2E-44 T 23-04-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 Gene3D G3DSA:3.90.110.10 163 440 3.1E-87 T 23-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 70 86 5.5E-37 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 91 104 5.5E-37 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 105 125 5.5E-37 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 134 151 5.5E-37 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 159 170 5.5E-37 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 5.5E-37 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 5.5E-37 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 SUPERFAMILY SSF56327 163 439 5.7E-53 T 23-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 134 164 - T 23-04-2016 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 PANTHER PTHR32092:SF5 329 441 1.0E-127 T 23-04-2016 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 PANTHER PTHR32092:SF5 1 309 1.0E-127 T 23-04-2016 DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 Gene3D G3DSA:3.40.50.720 1 162 2.8E-53 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS14975 295ca692ae933bcdb55b4958daa6eafd 446 SUPERFAMILY SSF51735 1 162 8.2E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02095 3f7cb914ad5d45e720c916d6c4c2b6b4 225 Hamap MF_00042 Ribonuclease H [rnhA]. 2 154 31.694 T 23-04-2016 IPR022892 Ribonuclease H GO:0004523 DC74_RS02095 3f7cb914ad5d45e720c916d6c4c2b6b4 225 Gene3D G3DSA:3.30.420.10 2 148 2.4E-43 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS02095 3f7cb914ad5d45e720c916d6c4c2b6b4 225 Pfam PF00075 RNase H 6 145 3.4E-30 T 23-04-2016 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 DC74_RS02095 3f7cb914ad5d45e720c916d6c4c2b6b4 225 SUPERFAMILY SSF53098 4 145 4.55E-39 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS02095 3f7cb914ad5d45e720c916d6c4c2b6b4 225 PANTHER PTHR10642 1 145 2.1E-35 T 23-04-2016 DC74_RS25370 c845a3d6cb93b2bbd0f6bdad41c41deb 136 SUPERFAMILY SSF55298 5 135 1.49E-30 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS25370 c845a3d6cb93b2bbd0f6bdad41c41deb 136 Pfam PF01042 Endoribonuclease L-PSP 15 134 1.9E-25 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS25370 c845a3d6cb93b2bbd0f6bdad41c41deb 136 Gene3D G3DSA:3.30.1330.40 2 135 5.3E-36 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS25370 c845a3d6cb93b2bbd0f6bdad41c41deb 136 PANTHER PTHR11803 15 135 2.0E-32 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS24550 b8ef0ac73ecbf48e32cdc26739816059 214 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 148 171 - T 23-04-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS24550 b8ef0ac73ecbf48e32cdc26739816059 214 Pfam PF00551 Formyl transferase 14 196 2.8E-54 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS24550 b8ef0ac73ecbf48e32cdc26739816059 214 Gene3D G3DSA:3.40.50.170 13 209 1.3E-70 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS24550 b8ef0ac73ecbf48e32cdc26739816059 214 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 13 206 1.8E-70 T 23-04-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 DC74_RS24550 b8ef0ac73ecbf48e32cdc26739816059 214 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 14 202 30.018 T 23-04-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 DC74_RS24550 b8ef0ac73ecbf48e32cdc26739816059 214 PANTHER PTHR10520 14 203 6.0E-82 T 23-04-2016 DC74_RS24550 b8ef0ac73ecbf48e32cdc26739816059 214 SUPERFAMILY SSF53328 14 210 7.59E-60 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS14015 ff7fefdf7a5ac9b424a15374f89be1e4 273 Gene3D G3DSA:3.40.710.10 7 265 7.6E-47 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS14015 ff7fefdf7a5ac9b424a15374f89be1e4 273 PANTHER PTHR22935:SF57 1 256 5.9E-130 T 23-04-2016 DC74_RS14015 ff7fefdf7a5ac9b424a15374f89be1e4 273 Pfam PF00144 Beta-lactamase 13 261 1.3E-39 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS14015 ff7fefdf7a5ac9b424a15374f89be1e4 273 SUPERFAMILY SSF56601 6 265 2.32E-55 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS14015 ff7fefdf7a5ac9b424a15374f89be1e4 273 PANTHER PTHR22935 1 256 5.9E-130 T 23-04-2016 DC74_RS30490 20c98e2aa47476bcbaa03d04dcb4dd84 504 Gene3D G3DSA:3.40.50.300 317 482 7.8E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30490 20c98e2aa47476bcbaa03d04dcb4dd84 504 Gene3D G3DSA:3.40.50.300 136 211 7.8E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30490 20c98e2aa47476bcbaa03d04dcb4dd84 504 SUPERFAMILY SSF52540 87 489 6.29E-36 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 5.3E-29 T 23-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 5.3E-29 T 23-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 5.3E-29 T 23-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 5.3E-29 T 23-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 5.3E-29 T 23-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 SUPERFAMILY SSF101353 249 443 2.48E-59 T 23-04-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7|Reactome: REACT_71 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 SUPERFAMILY SSF50447 462 561 5.3E-17 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 SMART SM00863 662 705 6.5E-21 T 23-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 Gene3D G3DSA:3.30.930.10 1 244 2.4E-95 T 23-04-2016 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 662 705 1.4E-17 T 23-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 SUPERFAMILY SSF55681 2 248 2.98E-90 T 23-04-2016 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 PANTHER PTHR11777 1 888 0.0 T 23-04-2016 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 SUPERFAMILY SSF55186 561 720 3.66E-42 T 23-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 868 9.5E-257 T 23-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 PANTHER PTHR11777:SF9 1 888 0.0 T 23-04-2016 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 889 167.831 T 23-04-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 Pfam PF02272 DHHA1 domain 814 882 4.3E-10 T 23-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 DC74_RS09525 ced915b9fd04088aa9faf3212599f153 889 Pfam PF01411 tRNA synthetases class II (A) 5 564 1.7E-192 T 23-04-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 DC74_RS37900 b4407625fb574aa2c6d9ddd7a8ad6620 332 Gene3D G3DSA:3.40.50.720 164 277 2.2E-23 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37900 b4407625fb574aa2c6d9ddd7a8ad6620 332 PANTHER PTHR11695:SF429 12 326 5.1E-98 T 23-04-2016 DC74_RS37900 b4407625fb574aa2c6d9ddd7a8ad6620 332 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS37900 b4407625fb574aa2c6d9ddd7a8ad6620 332 Pfam PF00107 Zinc-binding dehydrogenase 172 292 8.6E-13 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS37900 b4407625fb574aa2c6d9ddd7a8ad6620 332 PANTHER PTHR11695 12 326 5.1E-98 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS37900 b4407625fb574aa2c6d9ddd7a8ad6620 332 SUPERFAMILY SSF50129 301 328 2.28E-54 T 23-04-2016 IPR011032 GroES-like DC74_RS37900 b4407625fb574aa2c6d9ddd7a8ad6620 332 SUPERFAMILY SSF50129 1 139 2.28E-54 T 23-04-2016 IPR011032 GroES-like DC74_RS37900 b4407625fb574aa2c6d9ddd7a8ad6620 332 SUPERFAMILY SSF51735 134 296 6.08E-27 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37900 b4407625fb574aa2c6d9ddd7a8ad6620 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 130 2.2E-32 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS37900 b4407625fb574aa2c6d9ddd7a8ad6620 332 Gene3D G3DSA:3.90.180.10 1 163 1.7E-54 T 23-04-2016 IPR011032 GroES-like DC74_RS37900 b4407625fb574aa2c6d9ddd7a8ad6620 332 SMART SM00829 7 328 0.0089 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS30250 09a740b37f8fdaeb023d9e2518f0708e 167 PANTHER PTHR11002 1 154 4.2E-55 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS30250 09a740b37f8fdaeb023d9e2518f0708e 167 Pfam PF00484 Carbonic anhydrase 3 150 2.1E-33 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS30250 09a740b37f8fdaeb023d9e2518f0708e 167 SMART SM00947 1 155 1.0E-34 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS30250 09a740b37f8fdaeb023d9e2518f0708e 167 SUPERFAMILY SSF53056 1 154 1.31E-39 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS30250 09a740b37f8fdaeb023d9e2518f0708e 167 PANTHER PTHR11002:SF17 1 154 4.2E-55 T 23-04-2016 DC74_RS30250 09a740b37f8fdaeb023d9e2518f0708e 167 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 8 15 - T 23-04-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS30250 09a740b37f8fdaeb023d9e2518f0708e 167 Gene3D G3DSA:3.40.1050.10 1 155 1.7E-38 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS04195 2b104d6ba75d37b8353eb435afce86c8 218 PANTHER PTHR30055 3 179 2.4E-52 T 23-04-2016 DC74_RS04195 2b104d6ba75d37b8353eb435afce86c8 218 Gene3D G3DSA:1.10.10.60 5 58 3.6E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04195 2b104d6ba75d37b8353eb435afce86c8 218 PANTHER PTHR30055:SF81 3 179 2.4E-52 T 23-04-2016 DC74_RS04195 2b104d6ba75d37b8353eb435afce86c8 218 SUPERFAMILY SSF46689 7 81 1.65E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04195 2b104d6ba75d37b8353eb435afce86c8 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 61 1.7E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS04195 2b104d6ba75d37b8353eb435afce86c8 218 Gene3D G3DSA:1.10.357.10 67 209 5.4E-14 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS33135 869291e3a1bdf87ba06901451db408df 319 Pfam PF01965 DJ-1/PfpI family 5 172 2.2E-30 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS33135 869291e3a1bdf87ba06901451db408df 319 SUPERFAMILY SSF52317 5 192 2.03E-52 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS33135 869291e3a1bdf87ba06901451db408df 319 SUPERFAMILY SSF46689 212 260 1.32E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS33135 869291e3a1bdf87ba06901451db408df 319 SMART SM00342 227 310 6.1E-29 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS33135 869291e3a1bdf87ba06901451db408df 319 Pfam PF12833 Helix-turn-helix domain 233 312 2.6E-24 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS33135 869291e3a1bdf87ba06901451db408df 319 Gene3D G3DSA:3.40.50.880 5 217 2.4E-61 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS33135 869291e3a1bdf87ba06901451db408df 319 PANTHER PTHR11019:SF58 53 318 8.7E-118 T 23-04-2016 DC74_RS33135 869291e3a1bdf87ba06901451db408df 319 PANTHER PTHR11019 53 318 8.7E-118 T 23-04-2016 DC74_RS33135 869291e3a1bdf87ba06901451db408df 319 SUPERFAMILY SSF46689 263 314 4.39E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS33135 869291e3a1bdf87ba06901451db408df 319 Gene3D G3DSA:1.10.10.60 218 264 2.5E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS33135 869291e3a1bdf87ba06901451db408df 319 Gene3D G3DSA:1.10.10.60 265 314 6.0E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS20895 be5c015e6a3e87b61e4a666419e34621 239 SUPERFAMILY SSF48498 65 181 3.56E-7 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS20895 be5c015e6a3e87b61e4a666419e34621 239 PANTHER PTHR30055 1 140 9.0E-20 T 23-04-2016 DC74_RS20895 be5c015e6a3e87b61e4a666419e34621 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 44 6.0E-14 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS20895 be5c015e6a3e87b61e4a666419e34621 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 44 5.9E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS20895 be5c015e6a3e87b61e4a666419e34621 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 13 5.9E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS20895 be5c015e6a3e87b61e4a666419e34621 239 PANTHER PTHR30055:SF19 1 140 9.0E-20 T 23-04-2016 DC74_RS20895 be5c015e6a3e87b61e4a666419e34621 239 Gene3D G3DSA:1.10.357.10 1 182 3.5E-35 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS20895 be5c015e6a3e87b61e4a666419e34621 239 SUPERFAMILY SSF46689 1 67 1.55E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS36575 f2b00bc8384a325f0f831a803554cf60 386 Gene3D G3DSA:2.40.110.10 117 215 1.5E-5 T 23-04-2016 DC74_RS36575 f2b00bc8384a325f0f831a803554cf60 386 PIRSF PIRSF016578 1 372 1.2E-22 T 23-04-2016 DC74_RS36575 f2b00bc8384a325f0f831a803554cf60 386 Gene3D G3DSA:1.20.140.10 216 378 3.8E-16 T 23-04-2016 DC74_RS36575 f2b00bc8384a325f0f831a803554cf60 386 Gene3D G3DSA:1.10.540.10 13 110 9.7E-24 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS36575 f2b00bc8384a325f0f831a803554cf60 386 PANTHER PTHR10909:SF121 13 358 1.8E-20 T 23-04-2016 DC74_RS36575 f2b00bc8384a325f0f831a803554cf60 386 PANTHER PTHR10909 13 358 1.8E-20 T 23-04-2016 DC74_RS36575 f2b00bc8384a325f0f831a803554cf60 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 110 1.7E-18 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS36575 f2b00bc8384a325f0f831a803554cf60 386 SUPERFAMILY SSF56645 12 219 1.7E-36 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS36575 f2b00bc8384a325f0f831a803554cf60 386 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 238 361 1.7E-7 T 23-04-2016 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain DC74_RS36575 f2b00bc8384a325f0f831a803554cf60 386 SUPERFAMILY SSF47203 228 371 5.23E-8 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 SUPERFAMILY SSF50486 191 282 1.88E-9 T 23-04-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 593 991 1.2E-127 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 Pfam PF02911 Formyl transferase, C-terminal domain 191 282 3.4E-5 T 23-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 PANTHER PTHR24095 500 1184 1.2E-216 T 23-04-2016 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 ProSitePatterns PS00455 Putative AMP-binding domain signature. 717 728 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 SMART SM00823 Phosphopantetheine attachment site 1076 1145 0.0037 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 Gene3D G3DSA:1.10.1200.10 1082 1145 5.6E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 Gene3D G3DSA:3.40.50.170 2 181 2.5E-37 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 Gene3D G3DSA:3.40.50.980 565 726 1.4E-48 T 23-04-2016 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 Gene3D G3DSA:3.30.300.30 962 1081 1.0E-39 T 23-04-2016 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 Pfam PF13193 AMP-binding enzyme C-terminal domain 975 1049 7.4E-16 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 Pfam PF00550 Phosphopantetheine attachment site 1078 1141 1.2E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 PANTHER PTHR24095:SF137 500 1184 1.2E-216 T 23-04-2016 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 Pfam PF00501 AMP-binding enzyme 572 966 1.6E-101 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 Gene3D G3DSA:2.30.38.10 878 957 6.7E-27 T 23-04-2016 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 SUPERFAMILY SSF56801 538 1089 1.44E-157 T 23-04-2016 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 SUPERFAMILY SSF53328 2 185 3.66E-42 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 Gene3D G3DSA:3.40.50.980 727 877 2.6E-37 T 23-04-2016 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 Gene3D G3DSA:3.10.25.10 191 293 1.7E-9 T 23-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 SUPERFAMILY SSF47336 1073 1142 1.57E-16 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS26970 ca2594a394d63ba1fbad82471cccaa62 1195 Pfam PF00551 Formyl transferase 45 155 1.9E-21 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS32595 53e4e56b9edd74f00b2a8a108ec90514 198 Gene3D G3DSA:3.30.1130.10 72 193 1.2E-41 T 23-04-2016 DC74_RS32595 53e4e56b9edd74f00b2a8a108ec90514 198 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 122 132 - T 23-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 DC74_RS32595 53e4e56b9edd74f00b2a8a108ec90514 198 SUPERFAMILY SSF55620 18 192 1.11E-51 T 23-04-2016 DC74_RS32595 53e4e56b9edd74f00b2a8a108ec90514 198 PANTHER PTHR11109 21 188 5.8E-52 T 23-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 DC74_RS32595 53e4e56b9edd74f00b2a8a108ec90514 198 Gene3D G3DSA:1.10.286.10 21 57 5.3E-14 T 23-04-2016 DC74_RS32595 53e4e56b9edd74f00b2a8a108ec90514 198 Pfam PF01227 GTP cyclohydrolase I 23 192 1.1E-51 T 23-04-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 DC74_RS29790 89599740e16aa3e753759a8e11a3e066 355 Gene3D G3DSA:3.20.20.210 11 351 8.4E-148 T 23-04-2016 DC74_RS29790 89599740e16aa3e753759a8e11a3e066 355 PANTHER PTHR21091 17 350 5.0E-128 T 23-04-2016 DC74_RS29790 89599740e16aa3e753759a8e11a3e066 355 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 17 353 48.528 T 23-04-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 DC74_RS29790 89599740e16aa3e753759a8e11a3e066 355 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 17 351 1.4E-132 T 23-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 DC74_RS29790 89599740e16aa3e753759a8e11a3e066 355 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 33 42 - T 23-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 DC74_RS29790 89599740e16aa3e753759a8e11a3e066 355 PANTHER PTHR21091:SF2 17 350 5.0E-128 T 23-04-2016 DC74_RS29790 89599740e16aa3e753759a8e11a3e066 355 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 20 350 7.9E-124 T 23-04-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 DC74_RS29790 89599740e16aa3e753759a8e11a3e066 355 SUPERFAMILY SSF51726 15 351 7.06E-111 T 23-04-2016 DC74_RS29790 89599740e16aa3e753759a8e11a3e066 355 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 150 166 - T 23-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 DC74_RS06380 e353c203c0dd8c19e767f4a5bac438d7 354 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 51 266 9.4E-10 T 23-04-2016 IPR008775 Phytanoyl-CoA dioxygenase DC74_RS06380 e353c203c0dd8c19e767f4a5bac438d7 354 PANTHER PTHR31630 3 337 9.2E-82 T 23-04-2016 DC74_RS06380 e353c203c0dd8c19e767f4a5bac438d7 354 SUPERFAMILY SSF51197 40 333 5.4E-56 T 23-04-2016 DC74_RS06380 e353c203c0dd8c19e767f4a5bac438d7 354 Gene3D G3DSA:2.60.120.620 28 279 1.3E-32 T 23-04-2016 DC74_RS06380 e353c203c0dd8c19e767f4a5bac438d7 354 PANTHER PTHR31630:SF6 3 337 9.2E-82 T 23-04-2016 DC74_RS31705 bc87e9ffac23b1e57f5c116efe35adc0 176 PANTHER PTHR11106 1 175 5.9E-70 T 23-04-2016 DC74_RS31705 bc87e9ffac23b1e57f5c116efe35adc0 176 SUPERFAMILY SSF52949 2 174 4.37E-57 T 23-04-2016 DC74_RS31705 bc87e9ffac23b1e57f5c116efe35adc0 176 Gene3D G3DSA:3.40.220.10 2 174 1.3E-62 T 23-04-2016 DC74_RS31705 bc87e9ffac23b1e57f5c116efe35adc0 176 Pfam PF01661 Macro domain 21 138 1.9E-38 T 23-04-2016 IPR002589 Macro domain DC74_RS31705 bc87e9ffac23b1e57f5c116efe35adc0 176 SMART SM00506 4 138 9.2E-48 T 23-04-2016 IPR002589 Macro domain DC74_RS08585 957917df421c6ae7c59110a083776b53 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 5.9E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS08585 957917df421c6ae7c59110a083776b53 194 PANTHER PTHR30055:SF89 1 194 2.9E-72 T 23-04-2016 DC74_RS08585 957917df421c6ae7c59110a083776b53 194 SUPERFAMILY SSF48498 81 188 4.85E-17 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS08585 957917df421c6ae7c59110a083776b53 194 Gene3D G3DSA:1.10.357.10 68 189 1.1E-18 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS08585 957917df421c6ae7c59110a083776b53 194 Gene3D G3DSA:1.10.10.60 4 66 8.5E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS08585 957917df421c6ae7c59110a083776b53 194 SUPERFAMILY SSF46689 4 74 8.72E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS08585 957917df421c6ae7c59110a083776b53 194 PANTHER PTHR30055 1 194 2.9E-72 T 23-04-2016 DC74_RS17365 41d82c6b885c3ed0b59085237104102e 227 Gene3D G3DSA:3.10.350.10 180 227 1.0E-15 T 23-04-2016 IPR018392 LysM domain DC74_RS17365 41d82c6b885c3ed0b59085237104102e 227 Gene3D G3DSA:1.10.530.10 19 118 2.3E-40 T 23-04-2016 DC74_RS17365 41d82c6b885c3ed0b59085237104102e 227 Pfam PF01476 LysM domain 182 227 1.2E-12 T 23-04-2016 IPR018392 LysM domain DC74_RS17365 41d82c6b885c3ed0b59085237104102e 227 Pfam PF06737 Transglycosylase-like domain 41 116 6.0E-33 T 23-04-2016 IPR010618 Transglycosylase-like DC74_RS17365 41d82c6b885c3ed0b59085237104102e 227 SUPERFAMILY SSF53955 43 117 1.04E-30 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS17365 41d82c6b885c3ed0b59085237104102e 227 SMART SM00257 181 227 1.1E-8 T 23-04-2016 IPR018392 LysM domain DC74_RS17365 41d82c6b885c3ed0b59085237104102e 227 SUPERFAMILY SSF54106 180 227 3.66E-10 T 23-04-2016 IPR018392 LysM domain DC74_RS28375 7d89e4b95de618716399e0d0dc01c6c1 639 SUPERFAMILY SSF47203 280 437 9.02E-35 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS28375 7d89e4b95de618716399e0d0dc01c6c1 639 Gene3D G3DSA:2.40.110.10 169 266 6.6E-34 T 23-04-2016 DC74_RS28375 7d89e4b95de618716399e0d0dc01c6c1 639 PANTHER PTHR10909:SF145 28 457 1.3E-142 T 23-04-2016 DC74_RS28375 7d89e4b95de618716399e0d0dc01c6c1 639 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 278 436 2.4E-30 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS28375 7d89e4b95de618716399e0d0dc01c6c1 639 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 60 166 2.8E-20 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS28375 7d89e4b95de618716399e0d0dc01c6c1 639 PANTHER PTHR10909 28 457 1.3E-142 T 23-04-2016 DC74_RS28375 7d89e4b95de618716399e0d0dc01c6c1 639 Gene3D G3DSA:1.20.140.10 267 440 1.2E-48 T 23-04-2016 DC74_RS28375 7d89e4b95de618716399e0d0dc01c6c1 639 Gene3D G3DSA:1.10.540.10 30 168 4.1E-29 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS28375 7d89e4b95de618716399e0d0dc01c6c1 639 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 170 266 4.3E-22 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS28375 7d89e4b95de618716399e0d0dc01c6c1 639 SUPERFAMILY SSF56645 36 288 2.88E-61 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS03680 e168be55632f4b2e08bf40d349959a2c 495 SUPERFAMILY SSF53474 4 485 4.63E-99 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS03680 e168be55632f4b2e08bf40d349959a2c 495 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 166 181 - T 23-04-2016 IPR019826 Carboxylesterase type B, active site DC74_RS03680 e168be55632f4b2e08bf40d349959a2c 495 PANTHER PTHR11559 3 490 3.0E-120 T 23-04-2016 DC74_RS03680 e168be55632f4b2e08bf40d349959a2c 495 Gene3D G3DSA:3.40.50.1820 2 486 5.5E-110 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS03680 e168be55632f4b2e08bf40d349959a2c 495 PANTHER PTHR11559:SF142 3 490 3.0E-120 T 23-04-2016 DC74_RS03680 e168be55632f4b2e08bf40d349959a2c 495 Pfam PF00135 Carboxylesterase family 12 452 6.4E-79 T 23-04-2016 IPR002018 Carboxylesterase, type B DC74_RS02265 1121f4ecbe09b4221fe17d20e89c44a0 352 Gene3D G3DSA:3.30.470.20 200 335 1.7E-25 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS02265 1121f4ecbe09b4221fe17d20e89c44a0 352 SUPERFAMILY SSF52440 39 117 1.29E-5 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS02265 1121f4ecbe09b4221fe17d20e89c44a0 352 Pfam PF07478 D-ala D-ala ligase C-terminus 125 327 4.1E-24 T 23-04-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS02265 1121f4ecbe09b4221fe17d20e89c44a0 352 SUPERFAMILY SSF56059 119 327 8.37E-35 T 23-04-2016 DC74_RS02265 1121f4ecbe09b4221fe17d20e89c44a0 352 PANTHER PTHR23132 64 335 5.2E-46 T 23-04-2016 DC74_RS02265 1121f4ecbe09b4221fe17d20e89c44a0 352 Gene3D G3DSA:3.30.1490.20 110 199 1.2E-10 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS10015 1b2718cc0b53a7f330f7e7bd01757016 594 PANTHER PTHR24221 76 592 1.1E-152 T 23-04-2016 DC74_RS10015 1b2718cc0b53a7f330f7e7bd01757016 594 Gene3D G3DSA:1.20.1560.10 23 296 4.4E-14 T 23-04-2016 DC74_RS10015 1b2718cc0b53a7f330f7e7bd01757016 594 SUPERFAMILY SSF90123 19 296 1.57E-18 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS10015 1b2718cc0b53a7f330f7e7bd01757016 594 SMART SM00382 368 559 1.4E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS10015 1b2718cc0b53a7f330f7e7bd01757016 594 PANTHER PTHR24221:SF157 76 592 1.1E-152 T 23-04-2016 DC74_RS10015 1b2718cc0b53a7f330f7e7bd01757016 594 Pfam PF00005 ABC transporter 359 513 5.6E-33 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS10015 1b2718cc0b53a7f330f7e7bd01757016 594 SUPERFAMILY SSF52540 335 583 3.97E-77 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10015 1b2718cc0b53a7f330f7e7bd01757016 594 Gene3D G3DSA:3.40.50.300 342 577 1.7E-74 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10015 1b2718cc0b53a7f330f7e7bd01757016 594 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS07115 d1f62a8a0029731ee9bef7690607543e 180 SUPERFAMILY SSF88659 120 177 3.05E-13 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS07115 d1f62a8a0029731ee9bef7690607543e 180 Pfam PF08281 Sigma-70, region 4 122 173 1.3E-15 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS07115 d1f62a8a0029731ee9bef7690607543e 180 Gene3D G3DSA:1.10.10.10 122 179 2.3E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07115 d1f62a8a0029731ee9bef7690607543e 180 SUPERFAMILY SSF88946 2 102 7.06E-25 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS07115 d1f62a8a0029731ee9bef7690607543e 180 Gene3D G3DSA:1.10.1740.10 10 107 1.4E-25 T 23-04-2016 DC74_RS07115 d1f62a8a0029731ee9bef7690607543e 180 Pfam PF04542 Sigma-70 region 2 26 90 2.2E-16 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS07115 d1f62a8a0029731ee9bef7690607543e 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 173 2.2E-23 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS07115 d1f62a8a0029731ee9bef7690607543e 180 PANTHER PTHR30173:SF2 1 179 1.5E-82 T 23-04-2016 DC74_RS07115 d1f62a8a0029731ee9bef7690607543e 180 PANTHER PTHR30173 1 179 1.5E-82 T 23-04-2016 DC74_RS07115 d1f62a8a0029731ee9bef7690607543e 180 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 23-04-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS18510 e8d62cf8458db5a80b27a531faf7c6f1 157 Pfam PF00583 Acetyltransferase (GNAT) family 47 122 1.5E-14 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS18510 e8d62cf8458db5a80b27a531faf7c6f1 157 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 5 141 4.0E-32 T 23-04-2016 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 DC74_RS18510 e8d62cf8458db5a80b27a531faf7c6f1 157 Gene3D G3DSA:3.40.630.30 2 144 5.1E-32 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS18510 e8d62cf8458db5a80b27a531faf7c6f1 157 PANTHER PTHR23091:SF264 1 144 1.9E-31 T 23-04-2016 DC74_RS18510 e8d62cf8458db5a80b27a531faf7c6f1 157 PANTHER PTHR23091 1 144 1.9E-31 T 23-04-2016 DC74_RS18510 e8d62cf8458db5a80b27a531faf7c6f1 157 SUPERFAMILY SSF55729 2 146 5.85E-30 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS35235 156ff425399d9e2d5906e5312e3d48e8 388 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 2 244 1.9E-55 T 23-04-2016 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 DC74_RS35235 156ff425399d9e2d5906e5312e3d48e8 388 Gene3D G3DSA:3.60.21.10 2 265 2.3E-75 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS35235 156ff425399d9e2d5906e5312e3d48e8 388 PANTHER PTHR30337 1 274 2.6E-85 T 23-04-2016 DC74_RS35235 156ff425399d9e2d5906e5312e3d48e8 388 PANTHER PTHR30337:SF0 1 274 2.6E-85 T 23-04-2016 DC74_RS35235 156ff425399d9e2d5906e5312e3d48e8 388 SUPERFAMILY SSF56300 2 306 1.99E-56 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS35235 156ff425399d9e2d5906e5312e3d48e8 388 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 267 355 2.0E-10 T 23-04-2016 IPR026843 Nuclease SbcCD subunit D, C-terminal domain DC74_RS35235 156ff425399d9e2d5906e5312e3d48e8 388 Pfam PF00149 Calcineurin-like phosphoesterase 2 91 1.3E-11 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS39385 c11f487a2a261ae1f4f24fed3d50f48c 536 PANTHER PTHR11559 263 501 7.2E-130 T 23-04-2016 DC74_RS39385 c11f487a2a261ae1f4f24fed3d50f48c 536 PANTHER PTHR11559 1 247 7.2E-130 T 23-04-2016 DC74_RS39385 c11f487a2a261ae1f4f24fed3d50f48c 536 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 204 219 - T 23-04-2016 IPR019826 Carboxylesterase type B, active site DC74_RS39385 c11f487a2a261ae1f4f24fed3d50f48c 536 Pfam PF00135 Carboxylesterase family 39 503 3.4E-100 T 23-04-2016 IPR002018 Carboxylesterase, type B DC74_RS39385 c11f487a2a261ae1f4f24fed3d50f48c 536 SUPERFAMILY SSF53474 38 533 6.39E-110 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS39385 c11f487a2a261ae1f4f24fed3d50f48c 536 Gene3D G3DSA:3.40.50.1820 33 533 1.0E-128 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS40220 2bce15b44ea9e1abc1b4613f98466abe 606 Pfam PF16640 Bacterial Ig-like domain (group 3) 349 431 2.9E-17 T 23-04-2016 IPR032109 Bacterial Ig-like domain (group 3) DC74_RS40220 2bce15b44ea9e1abc1b4613f98466abe 606 Pfam PF12810 Glycine rich protein 82 334 5.3E-11 T 23-04-2016 DC74_RS34920 251f4db730140f9540610811bf4bae37 1020 Gene3D G3DSA:1.20.1270.50 522 620 1.7E-24 T 23-04-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 DC74_RS34920 251f4db730140f9540610811bf4bae37 1020 SUPERFAMILY SSF74650 660 1014 2.95E-58 T 23-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 DC74_RS34920 251f4db730140f9540610811bf4bae37 1020 SUPERFAMILY SSF88713 251 517 4.09E-76 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS34920 251f4db730140f9540610811bf4bae37 1020 SMART SM00872 519 597 4.9E-39 T 23-04-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 DC74_RS34920 251f4db730140f9540610811bf4bae37 1020 PANTHER PTHR11607:SF15 169 992 3.4E-300 T 23-04-2016 DC74_RS34920 251f4db730140f9540610811bf4bae37 1020 SUPERFAMILY SSF88688 518 621 3.92E-28 T 23-04-2016 IPR028995 Glycoside hydrolase families 57/38, central domain DC74_RS34920 251f4db730140f9540610811bf4bae37 1020 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 658 1009 6.6E-58 T 23-04-2016 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 DC74_RS34920 251f4db730140f9540610811bf4bae37 1020 Pfam PF09261 Alpha mannosidase middle domain 519 596 1.5E-27 T 23-04-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 DC74_RS34920 251f4db730140f9540610811bf4bae37 1020 PANTHER PTHR11607 169 992 3.4E-300 T 23-04-2016 DC74_RS34920 251f4db730140f9540610811bf4bae37 1020 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 255 509 1.1E-83 T 23-04-2016 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 DC74_RS34920 251f4db730140f9540610811bf4bae37 1020 Gene3D G3DSA:3.20.110.10 203 521 4.3E-85 T 23-04-2016 IPR027291 Glycoside hydrolase 38/57, N-terminal domain DC74_RS31945 0180797f3bca24d028e46eb4de263d89 234 Pfam PF09335 SNARE associated Golgi protein 51 180 2.5E-13 T 23-04-2016 IPR032816 SNARE associated Golgi protein DC74_RS31945 0180797f3bca24d028e46eb4de263d89 234 PANTHER PTHR30353 4 215 8.7E-27 T 23-04-2016 IPR032818 DedA family DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 PANTHER PTHR10668:SF68 236 623 3.7E-234 T 23-04-2016 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 PANTHER PTHR10668:SF68 40 202 3.7E-234 T 23-04-2016 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 PANTHER PTHR10668 236 623 3.7E-234 T 23-04-2016 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 PANTHER PTHR10668 40 202 3.7E-234 T 23-04-2016 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 Pfam PF00732 GMC oxidoreductase 259 347 2.0E-5 T 23-04-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 Pfam PF05199 GMC oxidoreductase 538 595 1.4E-13 T 23-04-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 Pfam PF00890 FAD binding domain 42 75 4.6E-5 T 23-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 SUPERFAMILY SSF51905 259 348 1.17E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 SUPERFAMILY SSF51905 40 191 1.17E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 SUPERFAMILY SSF51905 540 596 1.17E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 SUPERFAMILY SSF51905 402 413 1.17E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 Gene3D G3DSA:3.50.50.60 39 161 4.9E-82 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 Gene3D G3DSA:3.50.50.60 472 473 4.9E-82 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 Gene3D G3DSA:3.50.50.60 265 370 4.9E-82 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24035 79dfd177990c4f044b7410c438ef5a35 650 Gene3D G3DSA:3.50.50.60 534 602 4.9E-82 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 SUPERFAMILY SSF52540 307 515 9.46E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 SMART SM00382 30 242 2.3E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 SMART SM00382 346 516 3.3E-8 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 Pfam PF00005 ABC transporter 338 471 1.5E-21 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 Pfam PF00005 ABC transporter 21 188 3.7E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 Gene3D G3DSA:3.40.50.300 8 284 6.5E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 PANTHER PTHR19211:SF7 3 553 0.0 T 23-04-2016 DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 Gene3D G3DSA:3.40.50.300 319 534 1.2E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 Pfam PF12848 ABC transporter 227 297 6.6E-12 T 23-04-2016 IPR032781 ABC-transporter extension domain DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 PANTHER PTHR19211 3 553 0.0 T 23-04-2016 DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 SUPERFAMILY SSF52540 8 239 1.11E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15590 87ff8a1fc81e4199d1ce775fb5c9eed9 554 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 551 2.0E-272 T 23-04-2016 IPR022374 ABC transporter, ATP-binding protein, ChvD DC74_RS05060 83b8b314f940b8f32f9aa331e45c2108 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 304 328 4.3E-10 T 23-04-2016 DC74_RS05060 83b8b314f940b8f32f9aa331e45c2108 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 117 137 4.3E-10 T 23-04-2016 DC74_RS05060 83b8b314f940b8f32f9aa331e45c2108 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 26 50 4.3E-10 T 23-04-2016 DC74_RS05060 83b8b314f940b8f32f9aa331e45c2108 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 4.3E-10 T 23-04-2016 DC74_RS05060 83b8b314f940b8f32f9aa331e45c2108 469 Gene3D G3DSA:1.20.1250.20 275 447 1.3E-21 T 23-04-2016 DC74_RS05060 83b8b314f940b8f32f9aa331e45c2108 469 PANTHER PTHR23501 3 455 1.0E-79 T 23-04-2016 DC74_RS05060 83b8b314f940b8f32f9aa331e45c2108 469 Gene3D G3DSA:1.20.1250.20 20 200 3.3E-29 T 23-04-2016 DC74_RS05060 83b8b314f940b8f32f9aa331e45c2108 469 SUPERFAMILY SSF103473 10 204 3.79E-58 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05060 83b8b314f940b8f32f9aa331e45c2108 469 SUPERFAMILY SSF103473 250 453 3.79E-58 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05060 83b8b314f940b8f32f9aa331e45c2108 469 Pfam PF07690 Major Facilitator Superfamily 30 243 1.0E-30 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS05060 83b8b314f940b8f32f9aa331e45c2108 469 Pfam PF07690 Major Facilitator Superfamily 281 463 5.7E-15 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS31215 201552b4674a8cb10d8fb3bd83614e5a 75 Pfam PF03777 Small secreted domain (DUF320) 21 75 6.7E-29 T 23-04-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 PANTHER PTHR30603:SF0 29 325 2.6E-128 T 23-04-2016 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 Gene3D G3DSA:1.10.10.10 174 225 5.7E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 PRINTS PR00046 Major sigma-70 factor signature 309 320 2.3E-24 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 PRINTS PR00046 Major sigma-70 factor signature 294 309 2.3E-24 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 PRINTS PR00046 Major sigma-70 factor signature 149 157 2.3E-24 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 PRINTS PR00046 Major sigma-70 factor signature 273 285 2.3E-24 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 PRINTS PR00046 Major sigma-70 factor signature 125 138 2.3E-24 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 97 322 4.7E-33 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 Pfam PF04539 Sigma-70 region 3 180 256 1.9E-23 T 23-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 125 138 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 Gene3D G3DSA:1.10.601.10 24 170 1.1E-55 T 23-04-2016 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 Pfam PF04545 Sigma-70, region 4 270 321 1.6E-13 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 Gene3D G3DSA:1.10.10.10 264 327 6.1E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 Pfam PF04542 Sigma-70 region 2 101 171 1.3E-20 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 Pfam PF00140 Sigma-70 factor, region 1.2 33 66 4.7E-11 T 23-04-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 SUPERFAMILY SSF88946 33 171 8.86E-48 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 SUPERFAMILY SSF88659 232 327 3.66E-23 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 294 320 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 SUPERFAMILY SSF88659 174 247 6.41E-16 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17990 9870d235587215e6150bbae51bbba6e2 333 PANTHER PTHR30603 29 325 2.6E-128 T 23-04-2016 DC74_RS24135 71a716869aefacc6e461504c4e15878c 810 SMART SM00885 355 501 1.4E-30 T 23-04-2016 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal DC74_RS24135 71a716869aefacc6e461504c4e15878c 810 Pfam PF13155 Toprim-like 217 301 7.3E-5 T 23-04-2016 DC74_RS24135 71a716869aefacc6e461504c4e15878c 810 PANTHER PTHR35372:SF2 329 752 3.5E-64 T 23-04-2016 DC74_RS24135 71a716869aefacc6e461504c4e15878c 810 SUPERFAMILY SSF56731 110 319 2.54E-8 T 23-04-2016 DC74_RS24135 71a716869aefacc6e461504c4e15878c 810 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 451 760 3.2E-55 T 23-04-2016 IPR006500 DNA primase, phage/plasmid DC74_RS24135 71a716869aefacc6e461504c4e15878c 810 Pfam PF08706 D5 N terminal like 355 499 1.1E-29 T 23-04-2016 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal DC74_RS24135 71a716869aefacc6e461504c4e15878c 810 PANTHER PTHR35372 329 752 3.5E-64 T 23-04-2016 DC74_RS24135 71a716869aefacc6e461504c4e15878c 810 Pfam PF03288 Poxvirus D5 protein-like 714 765 2.8E-7 T 23-04-2016 IPR004968 DNA primase/nucleoside triphosphatase, C-terminal DC74_RS24135 71a716869aefacc6e461504c4e15878c 810 Gene3D G3DSA:3.40.1360.10 202 312 8.3E-7 T 23-04-2016 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 SUPERFAMILY SSF51569 39 349 1.01E-94 T 23-04-2016 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 SUPERFAMILY SSF110921 482 582 4.05E-36 T 23-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 57 73 - T 23-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 Pfam PF00682 HMGL-like 50 330 1.6E-73 T 23-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 25 585 54.217 T 23-04-2016 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 PANTHER PTHR10277 15 365 3.4E-270 T 23-04-2016 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 PANTHER PTHR10277 386 585 3.4E-270 T 23-04-2016 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 262 275 - T 23-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 Gene3D G3DSA:3.20.20.70 27 422 4.8E-144 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 SUPERFAMILY SSF89000 417 466 1.73E-15 T 23-04-2016 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 24 585 6.2E-259 T 23-04-2016 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 PANTHER PTHR10277:SF28 15 365 3.4E-270 T 23-04-2016 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 PANTHER PTHR10277:SF28 386 585 3.4E-270 T 23-04-2016 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 Pfam PF08502 LeuA allosteric (dimerisation) domain 451 582 6.1E-35 T 23-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS14925 b3f4fe16e991386314c9d522ee166294 585 SMART SM00917 451 584 5.8E-38 T 23-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS35160 921cb28219c8d99d8e32df89ddf2599a 154 Pfam PF13508 Acetyltransferase (GNAT) domain 55 132 1.1E-7 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS35160 921cb28219c8d99d8e32df89ddf2599a 154 SUPERFAMILY SSF55729 1 136 4.29E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS35160 921cb28219c8d99d8e32df89ddf2599a 154 Gene3D G3DSA:3.40.630.30 1 136 6.5E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS07905 279fe4f7e1029cec61efe5e578944fdd 194 Pfam PF01169 Uncharacterized protein family UPF0016 9 80 9.9E-16 T 23-04-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 DC74_RS07905 279fe4f7e1029cec61efe5e578944fdd 194 Pfam PF01169 Uncharacterized protein family UPF0016 111 183 8.9E-17 T 23-04-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 DC74_RS07905 279fe4f7e1029cec61efe5e578944fdd 194 PANTHER PTHR12608 7 194 8.7E-27 T 23-04-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 DC74_RS01990 66e48c620b32bf929659cd6203c6df71 315 SUPERFAMILY SSF53448 13 268 1.77E-50 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS01990 66e48c620b32bf929659cd6203c6df71 315 Gene3D G3DSA:3.90.550.10 17 266 1.6E-46 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS01990 66e48c620b32bf929659cd6203c6df71 315 Pfam PF02709 N-terminal domain of galactosyltransferase 182 237 1.4E-9 T 23-04-2016 IPR027791 Galactosyltransferase, C-terminal UniPathway: UPA00378 DC74_RS01990 66e48c620b32bf929659cd6203c6df71 315 Pfam PF00535 Glycosyl transferase family 2 18 145 1.7E-26 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS01990 66e48c620b32bf929659cd6203c6df71 315 PANTHER PTHR22916 8 160 5.3E-45 T 23-04-2016 DC74_RS01990 66e48c620b32bf929659cd6203c6df71 315 PANTHER PTHR22916 180 306 5.3E-45 T 23-04-2016 DC74_RS29430 43b95c7683c825c88821a66ce1bee3fd 123 Pfam PF02261 Aspartate decarboxylase 1 114 8.8E-55 T 23-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 DC74_RS29430 43b95c7683c825c88821a66ce1bee3fd 123 PANTHER PTHR21012:SF0 2 120 7.2E-70 T 23-04-2016 DC74_RS29430 43b95c7683c825c88821a66ce1bee3fd 123 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 123 74.473 T 23-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 DC74_RS29430 43b95c7683c825c88821a66ce1bee3fd 123 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 3.0E-33 T 23-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 DC74_RS29430 43b95c7683c825c88821a66ce1bee3fd 123 SUPERFAMILY SSF50692 1 118 2.86E-51 T 23-04-2016 IPR009010 Aspartate decarboxylase-like domain DC74_RS29430 43b95c7683c825c88821a66ce1bee3fd 123 PANTHER PTHR21012 2 120 7.2E-70 T 23-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 DC74_RS29430 43b95c7683c825c88821a66ce1bee3fd 123 Gene3D G3DSA:2.40.40.20 1 117 2.8E-58 T 23-04-2016 DC74_RS29430 43b95c7683c825c88821a66ce1bee3fd 123 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 5.4E-53 T 23-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 DC74_RS29430 43b95c7683c825c88821a66ce1bee3fd 123 PIRSF PIRSF006246 1 123 5.6E-55 T 23-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 DC74_RS07250 03edf09d57e621259536acd232a7f299 292 SUPERFAMILY SSF55729 20 271 1.12E-40 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS07250 03edf09d57e621259536acd232a7f299 292 Gene3D G3DSA:3.40.630.30 195 259 1.8E-4 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS07250 03edf09d57e621259536acd232a7f299 292 Gene3D G3DSA:3.40.630.30 146 194 4.0E-4 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS07250 03edf09d57e621259536acd232a7f299 292 Gene3D G3DSA:3.40.630.30 16 134 3.5E-12 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS07250 03edf09d57e621259536acd232a7f299 292 PANTHER PTHR21471 14 292 1.2E-49 T 23-04-2016 DC74_RS07250 03edf09d57e621259536acd232a7f299 292 PANTHER PTHR21471:SF52 14 292 1.2E-49 T 23-04-2016 DC74_RS25150 37b54c5bfc630d68a09672ca8c4bc36b 370 SMART SM00065 6 178 0.0084 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS25150 37b54c5bfc630d68a09672ca8c4bc36b 370 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 179 335 4.2E-24 T 23-04-2016 IPR000160 GGDEF domain DC74_RS25150 37b54c5bfc630d68a09672ca8c4bc36b 370 Pfam PF00990 Diguanylate cyclase, GGDEF domain 181 333 2.2E-26 T 23-04-2016 IPR000160 GGDEF domain DC74_RS25150 37b54c5bfc630d68a09672ca8c4bc36b 370 Gene3D G3DSA:3.30.450.40 3 173 1.8E-11 T 23-04-2016 IPR029016 GAF domain-like DC74_RS25150 37b54c5bfc630d68a09672ca8c4bc36b 370 Gene3D G3DSA:3.30.70.270 183 335 8.0E-33 T 23-04-2016 DC74_RS25150 37b54c5bfc630d68a09672ca8c4bc36b 370 SMART SM00267 170 340 8.7E-42 T 23-04-2016 IPR000160 GGDEF domain DC74_RS25150 37b54c5bfc630d68a09672ca8c4bc36b 370 SUPERFAMILY SSF55781 9 171 8.07E-12 T 23-04-2016 IPR029016 GAF domain-like DC74_RS25150 37b54c5bfc630d68a09672ca8c4bc36b 370 SUPERFAMILY SSF55073 186 336 5.1E-29 T 23-04-2016 IPR029787 Nucleotide cyclase DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.2E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 5.2E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 5.2E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 SUPERFAMILY SSF51735 7 257 1.61E-78 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 Pfam PF00106 short chain dehydrogenase 7 200 1.4E-63 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 Gene3D G3DSA:3.40.50.720 5 257 3.1E-82 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 PANTHER PTHR24322 156 188 2.3E-56 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 PANTHER PTHR24322 10 140 2.3E-56 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.2E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.2E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.2E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.2E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.2E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32310 c81827c7b58b7d86b9c2d261bc58d7e1 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.2E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13850 42f2bc2e8aa8893f43a35d43a2b1f255 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 7.8E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS13850 42f2bc2e8aa8893f43a35d43a2b1f255 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 7.8E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS13850 42f2bc2e8aa8893f43a35d43a2b1f255 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 7.8E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS13850 42f2bc2e8aa8893f43a35d43a2b1f255 282 Gene3D G3DSA:3.40.50.1820 10 278 9.2E-48 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS13850 42f2bc2e8aa8893f43a35d43a2b1f255 282 SUPERFAMILY SSF53474 13 278 7.82E-51 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS13850 42f2bc2e8aa8893f43a35d43a2b1f255 282 PANTHER PTHR10992:SF771 15 279 5.6E-40 T 23-04-2016 DC74_RS13850 42f2bc2e8aa8893f43a35d43a2b1f255 282 PRINTS PR00412 Epoxide hydrolase signature 58 73 3.8E-5 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS13850 42f2bc2e8aa8893f43a35d43a2b1f255 282 PRINTS PR00412 Epoxide hydrolase signature 113 126 3.8E-5 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS13850 42f2bc2e8aa8893f43a35d43a2b1f255 282 PRINTS PR00412 Epoxide hydrolase signature 254 276 3.8E-5 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS13850 42f2bc2e8aa8893f43a35d43a2b1f255 282 Pfam PF12697 Alpha/beta hydrolase family 34 265 1.5E-17 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS13850 42f2bc2e8aa8893f43a35d43a2b1f255 282 PANTHER PTHR10992 15 279 5.6E-40 T 23-04-2016 DC74_RS11125 87fb5c977750d87923f14e99dd52e6a0 115 SUPERFAMILY SSF55718 7 115 4.0E-17 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS11125 87fb5c977750d87923f14e99dd52e6a0 115 Pfam PF02036 SCP-2 sterol transfer family 30 103 3.7E-5 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS11125 87fb5c977750d87923f14e99dd52e6a0 115 Gene3D G3DSA:3.30.1050.10 7 115 4.9E-16 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS34215 e932728d48de75b852b60b6847214f3e 389 PANTHER PTHR21021 116 380 8.5E-26 T 23-04-2016 DC74_RS34215 e932728d48de75b852b60b6847214f3e 389 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 191 379 8.6E-34 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS34215 e932728d48de75b852b60b6847214f3e 389 SMART SM00331 161 381 2.2E-15 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS34215 e932728d48de75b852b60b6847214f3e 389 SUPERFAMILY SSF81606 224 330 1.22E-8 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS03160 2b2f3ca43cc5c79f238ac787cb45f08f 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.64E-5 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS03160 2b2f3ca43cc5c79f238ac787cb45f08f 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.64E-5 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS03160 2b2f3ca43cc5c79f238ac787cb45f08f 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.64E-5 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS03160 2b2f3ca43cc5c79f238ac787cb45f08f 301 Gene3D G3DSA:1.10.10.10 7 83 3.6E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03160 2b2f3ca43cc5c79f238ac787cb45f08f 301 SUPERFAMILY SSF46785 6 97 1.75E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03160 2b2f3ca43cc5c79f238ac787cb45f08f 301 PANTHER PTHR30126 1 145 9.1E-19 T 23-04-2016 DC74_RS03160 2b2f3ca43cc5c79f238ac787cb45f08f 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 3.7E-16 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 SUPERFAMILY SSF46894 149 219 2.07E-18 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 PANTHER PTHR26402 19 219 1.0E-132 T 23-04-2016 DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 PANTHER PTHR26402:SF523 19 219 1.0E-132 T 23-04-2016 DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 SUPERFAMILY SSF52172 17 121 1.99E-11 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 2.5E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 Pfam PF00072 Response regulator receiver domain 26 116 2.2E-5 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 2.8E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 2.8E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 2.8E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 Gene3D G3DSA:3.40.50.2300 20 117 2.5E-9 T 23-04-2016 DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 SMART SM00421 156 213 1.0E-21 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS29780 57a728ab5f449b09fd8d8acfc20683cb 220 Gene3D G3DSA:1.10.10.10 144 218 2.5E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16085 48b7e44eee76187fb96dfb655d3109c5 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 33 314 4.2E-6 T 23-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 DC74_RS16085 48b7e44eee76187fb96dfb655d3109c5 324 SUPERFAMILY SSF51735 103 284 4.22E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16085 48b7e44eee76187fb96dfb655d3109c5 324 SUPERFAMILY SSF52283 34 131 1.34E-9 T 23-04-2016 DC74_RS16085 48b7e44eee76187fb96dfb655d3109c5 324 Gene3D G3DSA:3.40.50.720 111 284 4.8E-53 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16085 48b7e44eee76187fb96dfb655d3109c5 324 PANTHER PTHR10996 1 322 5.9E-140 T 23-04-2016 DC74_RS16085 48b7e44eee76187fb96dfb655d3109c5 324 PANTHER PTHR10996:SF122 1 322 5.9E-140 T 23-04-2016 DC74_RS16085 48b7e44eee76187fb96dfb655d3109c5 324 Gene3D G3DSA:3.40.50.720 9 110 3.4E-7 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16085 48b7e44eee76187fb96dfb655d3109c5 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 283 9.6E-45 T 23-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DC74_RS12870 50c7555f3ac1c5e6da8f541c690fb305 85 Gene3D G3DSA:1.10.10.10 4 76 7.9E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS12870 50c7555f3ac1c5e6da8f541c690fb305 85 PANTHER PTHR11751 13 78 4.0E-15 T 23-04-2016 DC74_RS12870 50c7555f3ac1c5e6da8f541c690fb305 85 SUPERFAMILY SSF46785 3 76 1.32E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS12870 50c7555f3ac1c5e6da8f541c690fb305 85 SMART SM00345 14 72 4.0E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS12870 50c7555f3ac1c5e6da8f541c690fb305 85 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 72 2.1E-14 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS12870 50c7555f3ac1c5e6da8f541c690fb305 85 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.2E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS12870 50c7555f3ac1c5e6da8f541c690fb305 85 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.2E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS26500 c90666f47833e9fbc1f76c523f71e4b5 162 SUPERFAMILY SSF55729 1 148 1.41E-38 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS26500 c90666f47833e9fbc1f76c523f71e4b5 162 Gene3D G3DSA:3.40.630.30 2 154 9.7E-60 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS26500 c90666f47833e9fbc1f76c523f71e4b5 162 Pfam PF00583 Acetyltransferase (GNAT) family 53 134 6.8E-16 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS26500 c90666f47833e9fbc1f76c523f71e4b5 162 PANTHER PTHR10545 2 157 2.5E-62 T 23-04-2016 DC74_RS02080 8f521efadbd897d0265a6cf5b60cd538 404 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 254 369 1.1E-10 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS02080 8f521efadbd897d0265a6cf5b60cd538 404 PANTHER PTHR11926 1 391 3.2E-19 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS02080 8f521efadbd897d0265a6cf5b60cd538 404 PANTHER PTHR11926:SF16 1 391 3.2E-19 T 23-04-2016 DC74_RS02080 8f521efadbd897d0265a6cf5b60cd538 404 Gene3D G3DSA:3.40.50.2000 1 220 4.5E-14 T 23-04-2016 DC74_RS02080 8f521efadbd897d0265a6cf5b60cd538 404 SUPERFAMILY SSF53756 1 399 1.53E-58 T 23-04-2016 DC74_RS02080 8f521efadbd897d0265a6cf5b60cd538 404 Gene3D G3DSA:3.40.50.2000 221 381 5.1E-35 T 23-04-2016 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 SMART SM00846 3 153 2.0E-94 T 23-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 SUPERFAMILY SSF51735 2 179 9.01E-63 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 Gene3D G3DSA:3.30.360.10 162 315 9.9E-75 T 23-04-2016 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 PANTHER PTHR10836:SF50 2 330 2.3E-212 T 23-04-2016 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 1.2E-137 T 23-04-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 9.6E-41 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 9.6E-41 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 9.6E-41 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 9.6E-41 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 9.6E-41 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 153 6.0E-60 T 23-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 SUPERFAMILY SSF55347 153 314 4.76E-70 T 23-04-2016 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 PIRSF PIRSF000149 1 332 7.1E-135 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 313 2.1E-68 T 23-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 Gene3D G3DSA:3.40.50.720 3 161 7.8E-75 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11830 d17de8edccfd4968cd7a06daf16ff001 334 PANTHER PTHR10836 2 330 2.3E-212 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS14260 9fb94a7f5cfd8a232f9dcad57873a225 110 SUPERFAMILY SSF47729 1 90 8.98E-22 T 23-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 DC74_RS14260 9fb94a7f5cfd8a232f9dcad57873a225 110 SMART SM00411 1 89 7.5E-26 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS14260 9fb94a7f5cfd8a232f9dcad57873a225 110 Pfam PF00216 Bacterial DNA-binding protein 1 88 6.7E-22 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS14260 9fb94a7f5cfd8a232f9dcad57873a225 110 Gene3D G3DSA:4.10.520.10 1 89 8.4E-24 T 23-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 DC74_RS14260 9fb94a7f5cfd8a232f9dcad57873a225 110 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 2.5E-8 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS14260 9fb94a7f5cfd8a232f9dcad57873a225 110 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 2.5E-8 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS14260 9fb94a7f5cfd8a232f9dcad57873a225 110 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 2.5E-8 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS14260 9fb94a7f5cfd8a232f9dcad57873a225 110 PANTHER PTHR33175 1 110 1.4E-27 T 23-04-2016 DC74_RS18160 935589fb2307db1ef56c47cac9a0f45e 133 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 99 119 - T 23-04-2016 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 DC74_RS18160 935589fb2307db1ef56c47cac9a0f45e 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 120 7.1E-5 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS18160 935589fb2307db1ef56c47cac9a0f45e 133 Gene3D G3DSA:3.10.180.10 3 127 1.5E-18 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS18160 935589fb2307db1ef56c47cac9a0f45e 133 SUPERFAMILY SSF54593 3 125 1.47E-17 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 PANTHER PTHR11689 8 439 6.9E-55 T 23-04-2016 DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 PANTHER PTHR11689:SF14 8 439 6.9E-55 T 23-04-2016 DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 PRINTS PR00762 Chloride channel signature 155 174 1.9E-23 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 PRINTS PR00762 Chloride channel signature 348 364 1.9E-23 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 PRINTS PR00762 Chloride channel signature 366 385 1.9E-23 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 PRINTS PR00762 Chloride channel signature 319 339 1.9E-23 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 PRINTS PR00762 Chloride channel signature 104 123 1.9E-23 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 Gene3D G3DSA:3.10.580.10 463 514 2.2E-7 T 23-04-2016 DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 SMART SM00116 463 513 6.0E-6 T 23-04-2016 IPR000644 CBS domain DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 SUPERFAMILY SSF81340 3 419 1.2E-87 T 23-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 Gene3D G3DSA:1.10.3080.10 8 419 5.1E-68 T 23-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 SUPERFAMILY SSF54631 463 514 8.78E-8 T 23-04-2016 DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 Pfam PF00571 CBS domain 439 512 4.2E-7 T 23-04-2016 IPR000644 CBS domain DC74_RS38940 d823bd92712bcb760598fcedb901e428 539 Pfam PF00654 Voltage gated chloride channel 61 397 6.6E-69 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 DC74_RS15745 b5aa84dc51784bcc71fa08018c6108b2 344 Gene3D G3DSA:3.40.50.720 1 129 8.9E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15745 b5aa84dc51784bcc71fa08018c6108b2 344 SUPERFAMILY SSF55347 125 280 1.28E-26 T 23-04-2016 DC74_RS15745 b5aa84dc51784bcc71fa08018c6108b2 344 PANTHER PTHR22604 1 338 4.4E-100 T 23-04-2016 DC74_RS15745 b5aa84dc51784bcc71fa08018c6108b2 344 SUPERFAMILY SSF51735 1 146 2.24E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15745 b5aa84dc51784bcc71fa08018c6108b2 344 Gene3D G3DSA:3.30.360.10 130 329 2.3E-51 T 23-04-2016 DC74_RS15745 b5aa84dc51784bcc71fa08018c6108b2 344 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 161 234 4.9E-8 T 23-04-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 DC74_RS15745 b5aa84dc51784bcc71fa08018c6108b2 344 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 118 3.6E-18 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 DC74_RS15745 b5aa84dc51784bcc71fa08018c6108b2 344 PANTHER PTHR22604:SF92 1 338 4.4E-100 T 23-04-2016 DC74_RS20465 39395c3cd343edadb7f0137d293848c7 327 Pfam PF05138 Phenylacetic acid catabolic protein 25 299 9.4E-106 T 23-04-2016 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 UniPathway: UPA00930 DC74_RS20465 39395c3cd343edadb7f0137d293848c7 327 PANTHER PTHR30458:SF0 1 310 1.3E-166 T 23-04-2016 DC74_RS20465 39395c3cd343edadb7f0137d293848c7 327 Gene3D G3DSA:1.20.1260.10 25 280 2.5E-108 T 23-04-2016 IPR012347 Ferritin-related DC74_RS20465 39395c3cd343edadb7f0137d293848c7 327 PANTHER PTHR30458 1 310 1.3E-166 T 23-04-2016 DC74_RS20465 39395c3cd343edadb7f0137d293848c7 327 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 15 303 1.3E-159 T 23-04-2016 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149+1.14.13.14|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176|UniPathway: UPA00930 DC74_RS20465 39395c3cd343edadb7f0137d293848c7 327 SUPERFAMILY SSF47240 35 277 2.76E-84 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS18800 9a68676810b991cfd3f98af8dd2cdb9f 144 Gene3D G3DSA:3.30.1550.10 5 74 9.9E-39 T 23-04-2016 IPR020784 Ribosomal protein L11, N-terminal DC74_RS18800 9a68676810b991cfd3f98af8dd2cdb9f 144 SUPERFAMILY SSF46906 70 143 5.23E-27 T 23-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 DC74_RS18800 9a68676810b991cfd3f98af8dd2cdb9f 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 142 1.8E-25 T 23-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 DC74_RS18800 9a68676810b991cfd3f98af8dd2cdb9f 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 6 143 1.1E-63 T 23-04-2016 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 DC74_RS18800 9a68676810b991cfd3f98af8dd2cdb9f 144 SUPERFAMILY SSF54747 5 75 3.53E-30 T 23-04-2016 IPR020784 Ribosomal protein L11, N-terminal DC74_RS18800 9a68676810b991cfd3f98af8dd2cdb9f 144 PANTHER PTHR11661 1 144 2.7E-74 T 23-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 DC74_RS18800 9a68676810b991cfd3f98af8dd2cdb9f 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 23-04-2016 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 DC74_RS18800 9a68676810b991cfd3f98af8dd2cdb9f 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 12 69 1.5E-29 T 23-04-2016 IPR020784 Ribosomal protein L11, N-terminal DC74_RS18800 9a68676810b991cfd3f98af8dd2cdb9f 144 SMART SM00649 12 143 1.7E-86 T 23-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 DC74_RS18800 9a68676810b991cfd3f98af8dd2cdb9f 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 76 2.0E-16 T 23-04-2016 DC74_RS18800 9a68676810b991cfd3f98af8dd2cdb9f 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 8 144 31.82 T 23-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 DC74_RS18800 9a68676810b991cfd3f98af8dd2cdb9f 144 Gene3D G3DSA:1.10.10.250 75 143 1.4E-32 T 23-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 DC74_RS19035 5a8076dbd678346bde9d606bc95a00c7 214 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 143 28.612 T 23-04-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 DC74_RS19035 5a8076dbd678346bde9d606bc95a00c7 214 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 10 137 2.0E-44 T 23-04-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 DC74_RS19035 5a8076dbd678346bde9d606bc95a00c7 214 PANTHER PTHR10849:SF13 3 139 4.4E-60 T 23-04-2016 DC74_RS19035 5a8076dbd678346bde9d606bc95a00c7 214 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS19035 5a8076dbd678346bde9d606bc95a00c7 214 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 54 65 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS19035 5a8076dbd678346bde9d606bc95a00c7 214 Pfam PF12838 4Fe-4S dicluster domain 53 113 4.1E-11 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS19035 5a8076dbd678346bde9d606bc95a00c7 214 PANTHER PTHR10849 3 139 4.4E-60 T 23-04-2016 DC74_RS19035 5a8076dbd678346bde9d606bc95a00c7 214 Gene3D G3DSA:1.10.1060.10 10 126 2.4E-20 T 23-04-2016 DC74_RS19035 5a8076dbd678346bde9d606bc95a00c7 214 SUPERFAMILY SSF54862 27 145 7.53E-28 T 23-04-2016 DC74_RS28410 8b1c31a9cc6d9050a0fa227a802f4b27 302 SUPERFAMILY SSF56112 30 281 2.4E-11 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS28410 8b1c31a9cc6d9050a0fa227a802f4b27 302 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 42 284 3.7E-56 T 23-04-2016 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 407 4.3E-119 T 23-04-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 Gene3D G3DSA:3.40.1160.10 3 245 9.9E-72 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 PANTHER PTHR21499 3 418 4.7E-181 T 23-04-2016 DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 407 2.5E-127 T 23-04-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 23-04-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 Pfam PF01842 ACT domain 269 331 6.9E-9 T 23-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 PANTHER PTHR21499:SF27 3 418 4.7E-181 T 23-04-2016 DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 SUPERFAMILY SSF55021 335 410 2.15E-22 T 23-04-2016 DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 Pfam PF13840 ACT domain 342 404 1.1E-13 T 23-04-2016 IPR027795 GATS-like ACT domain DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 SUPERFAMILY SSF55021 251 330 3.77E-19 T 23-04-2016 DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 SUPERFAMILY SSF53633 4 244 9.69E-72 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 Pfam PF00696 Amino acid kinase family 3 231 2.6E-55 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 DC74_RS21945 fb3d2db76c00f6268c4c8471759ae27d 423 PIRSF PIRSF000726 59 415 3.0E-129 T 23-04-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 Gene3D G3DSA:1.10.510.10 113 283 3.2E-37 T 23-04-2016 DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 149 161 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 SMART SM00220 30 294 9.1E-44 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 Gene3D G3DSA:1.20.1250.20 845 870 1.1E-16 T 23-04-2016 DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 Gene3D G3DSA:1.20.1250.20 646 800 1.1E-16 T 23-04-2016 DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 SUPERFAMILY SSF56112 27 360 9.85E-61 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 PANTHER PTHR23501 327 869 3.7E-108 T 23-04-2016 DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 SUPERFAMILY SSF103473 386 581 2.49E-57 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 SUPERFAMILY SSF103473 627 799 2.49E-57 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 SUPERFAMILY SSF103473 844 869 2.49E-57 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 36 58 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 Pfam PF07690 Major Facilitator Superfamily 395 790 2.1E-44 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 Gene3D G3DSA:3.30.200.20 22 105 1.2E-14 T 23-04-2016 DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 Pfam PF00069 Protein kinase domain 30 282 2.9E-37 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS40240 e8b8e38cec6b905a1b1433aa896c5b92 897 Gene3D G3DSA:1.20.1250.20 385 574 3.9E-31 T 23-04-2016 DC74_RS34320 6f31577e886020e6cbfef02c4b67f399 363 PANTHER PTHR30344 21 345 6.3E-99 T 23-04-2016 DC74_RS34320 6f31577e886020e6cbfef02c4b67f399 363 SUPERFAMILY SSF51004 30 352 1.05E-41 T 23-04-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain DC74_RS34320 6f31577e886020e6cbfef02c4b67f399 363 PANTHER PTHR30344:SF1 21 345 6.3E-99 T 23-04-2016 DC74_RS34320 6f31577e886020e6cbfef02c4b67f399 363 Gene3D G3DSA:2.130.10.10 22 363 2.0E-98 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS34320 6f31577e886020e6cbfef02c4b67f399 363 Pfam PF10282 Lactonase, 7-bladed beta-propeller 23 362 7.0E-97 T 23-04-2016 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31|UniPathway: UPA00115 DC74_RS05550 6982b3c2a75c3f02e72d99d0dd61f3a0 234 Gene3D G3DSA:3.90.230.10 18 170 1.1E-8 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS05550 6982b3c2a75c3f02e72d99d0dd61f3a0 234 Pfam PF00557 Metallopeptidase family M24 20 163 2.2E-12 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS05550 6982b3c2a75c3f02e72d99d0dd61f3a0 234 SUPERFAMILY SSF55920 21 174 1.96E-13 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS02485 84e5703e232810be1991810003fcbb6d 389 PANTHER PTHR13794:SF55 4 321 4.7E-52 T 23-04-2016 DC74_RS02485 84e5703e232810be1991810003fcbb6d 389 SMART SM00922 163 260 1.2E-11 T 23-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DC74_RS02485 84e5703e232810be1991810003fcbb6d 389 Gene3D G3DSA:3.30.390.10 9 134 5.6E-24 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS02485 84e5703e232810be1991810003fcbb6d 389 SUPERFAMILY SSF51604 162 379 1.57E-36 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS02485 84e5703e232810be1991810003fcbb6d 389 PANTHER PTHR13794 4 321 4.7E-52 T 23-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 DC74_RS02485 84e5703e232810be1991810003fcbb6d 389 Gene3D G3DSA:3.20.20.120 158 379 2.1E-36 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS02485 84e5703e232810be1991810003fcbb6d 389 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 11 132 1.2E-7 T 23-04-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain DC74_RS02485 84e5703e232810be1991810003fcbb6d 389 SUPERFAMILY SSF54826 9 134 1.29E-17 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS02485 84e5703e232810be1991810003fcbb6d 389 Pfam PF13378 Enolase C-terminal domain-like 174 379 2.0E-32 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS26380 b6ac78445b7a9f22dac292d7887f3066 412 SUPERFAMILY SSF109604 260 405 3.87E-12 T 23-04-2016 DC74_RS26380 b6ac78445b7a9f22dac292d7887f3066 412 Gene3D G3DSA:1.10.3210.10 261 367 1.9E-7 T 23-04-2016 IPR006674 HD domain DC74_RS26380 b6ac78445b7a9f22dac292d7887f3066 412 Pfam PF01966 HD domain 262 300 8.5E-5 T 23-04-2016 IPR006674 HD domain DC74_RS17380 4d6413415d253fd1551c0f53403047fd 291 Pfam PF03466 LysR substrate binding domain 87 284 5.3E-43 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS17380 4d6413415d253fd1551c0f53403047fd 291 Gene3D G3DSA:3.40.190.10 177 261 1.8E-27 T 23-04-2016 DC74_RS17380 4d6413415d253fd1551c0f53403047fd 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.6E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS17380 4d6413415d253fd1551c0f53403047fd 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.6E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS17380 4d6413415d253fd1551c0f53403047fd 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.6E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS17380 4d6413415d253fd1551c0f53403047fd 291 Gene3D G3DSA:3.40.190.10 90 176 4.9E-19 T 23-04-2016 DC74_RS17380 4d6413415d253fd1551c0f53403047fd 291 PANTHER PTHR30346 1 284 9.0E-76 T 23-04-2016 DC74_RS17380 4d6413415d253fd1551c0f53403047fd 291 Gene3D G3DSA:1.10.10.10 1 85 8.7E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17380 4d6413415d253fd1551c0f53403047fd 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-23 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS17380 4d6413415d253fd1551c0f53403047fd 291 SUPERFAMILY SSF53850 86 284 3.26E-40 T 23-04-2016 DC74_RS17380 4d6413415d253fd1551c0f53403047fd 291 SUPERFAMILY SSF46785 1 86 7.3E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 ProSitePatterns PS00450 Aconitase family signature 1. 437 453 - T 23-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 SUPERFAMILY SSF52016 641 901 1.51E-84 T 23-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PANTHER PTHR11670 677 722 0.0 T 23-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PANTHER PTHR11670:SF1 763 904 0.0 T 23-04-2016 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 Gene3D G3DSA:3.20.19.10 647 901 2.2E-76 T 23-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 Pfam PF00330 Aconitase family (aconitate hydratase) 64 572 1.4E-181 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 ProSitePatterns PS01244 Aconitase family signature 2. 503 516 - T 23-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 Gene3D G3DSA:3.40.1060.10 241 358 1.1E-35 T 23-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 SUPERFAMILY SSF53732 4 637 7.32E-220 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PANTHER PTHR11670:SF1 1 384 0.0 T 23-04-2016 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PANTHER PTHR11670 1 384 0.0 T 23-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 26 901 0.0 T 23-04-2016 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PANTHER PTHR11670:SF1 426 661 0.0 T 23-04-2016 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 Pfam PF00694 Aconitase C-terminal domain 702 831 4.5E-44 T 23-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 Gene3D G3DSA:3.30.499.10 360 384 8.1E-64 T 23-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 Gene3D G3DSA:3.30.499.10 429 584 8.1E-64 T 23-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PANTHER PTHR11670 426 661 0.0 T 23-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PANTHER PTHR11670 763 904 0.0 T 23-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PRINTS PR00415 Aconitase family signature 270 283 3.4E-42 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PRINTS PR00415 Aconitase family signature 141 154 3.4E-42 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PRINTS PR00415 Aconitase family signature 284 297 3.4E-42 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PRINTS PR00415 Aconitase family signature 363 377 3.4E-42 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PRINTS PR00415 Aconitase family signature 165 173 3.4E-42 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PRINTS PR00415 Aconitase family signature 194 207 3.4E-42 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PRINTS PR00415 Aconitase family signature 503 516 3.4E-42 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PRINTS PR00415 Aconitase family signature 441 452 3.4E-42 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PRINTS PR00415 Aconitase family signature 208 223 3.4E-42 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 Gene3D G3DSA:3.30.499.10 28 240 9.3E-79 T 23-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS29695 4f509a9e935cab30e432bfdb12b577f6 904 PANTHER PTHR11670:SF1 677 722 0.0 T 23-04-2016 DC74_RS09555 d82705d9c770e83df228a54a48b68c71 452 SMART SM00382 61 182 3.5E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS09555 d82705d9c770e83df228a54a48b68c71 452 PANTHER PTHR13779:SF7 7 445 3.7E-182 T 23-04-2016 DC74_RS09555 d82705d9c770e83df228a54a48b68c71 452 PANTHER PTHR13779 7 445 3.7E-182 T 23-04-2016 DC74_RS09555 d82705d9c770e83df228a54a48b68c71 452 Gene3D G3DSA:1.10.8.60 201 251 6.0E-6 T 23-04-2016 DC74_RS09555 d82705d9c770e83df228a54a48b68c71 452 Pfam PF16193 AAA C-terminal domain 200 276 3.2E-25 T 23-04-2016 IPR032423 AAA ATPase, C-terminal domain DC74_RS09555 d82705d9c770e83df228a54a48b68c71 452 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 65 169 3.1E-13 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS09555 d82705d9c770e83df228a54a48b68c71 452 Gene3D G3DSA:1.20.272.10 258 356 2.1E-45 T 23-04-2016 DC74_RS09555 d82705d9c770e83df228a54a48b68c71 452 SUPERFAMILY SSF52540 20 245 3.36E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09555 d82705d9c770e83df228a54a48b68c71 452 Pfam PF12002 MgsA AAA+ ATPase C terminal 277 441 2.2E-71 T 23-04-2016 IPR021886 MgsA AAA+ ATPase C-terminal DC74_RS09555 d82705d9c770e83df228a54a48b68c71 452 Gene3D G3DSA:1.10.3710.10 357 448 9.6E-30 T 23-04-2016 DC74_RS09555 d82705d9c770e83df228a54a48b68c71 452 Gene3D G3DSA:3.40.50.300 11 170 1.5E-29 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09555 d82705d9c770e83df228a54a48b68c71 452 SUPERFAMILY SSF48019 262 445 4.0E-75 T 23-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 DC74_RS21970 6e6abeb18375466aefad57607e311fc5 612 SUPERFAMILY SSF82171 23 321 2.04E-24 T 23-04-2016 DC74_RS21970 6e6abeb18375466aefad57607e311fc5 612 Gene3D G3DSA:2.120.10.30 139 306 2.7E-12 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS21970 6e6abeb18375466aefad57607e311fc5 612 SUPERFAMILY SSF53474 344 591 4.99E-53 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS21970 6e6abeb18375466aefad57607e311fc5 612 Gene3D G3DSA:3.40.50.1820 34 73 2.2E-70 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS21970 6e6abeb18375466aefad57607e311fc5 612 Gene3D G3DSA:3.40.50.1820 311 591 2.2E-70 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS21970 6e6abeb18375466aefad57607e311fc5 612 PANTHER PTHR11731 4 604 1.6E-96 T 23-04-2016 DC74_RS21970 6e6abeb18375466aefad57607e311fc5 612 PANTHER PTHR11731:SF75 4 604 1.6E-96 T 23-04-2016 DC74_RS21970 6e6abeb18375466aefad57607e311fc5 612 Pfam PF00326 Prolyl oligopeptidase family 388 592 5.8E-40 T 23-04-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 SUPERFAMILY SSF55874 725 808 2.15E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 SUPERFAMILY SSF55781 341 439 7.63E-13 T 23-04-2016 IPR029016 GAF domain-like DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 SUPERFAMILY SSF55785 15 108 3.22E-9 T 23-04-2016 IPR000014 PAS domain DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 PANTHER PTHR21021:SF19 441 691 4.1E-42 T 23-04-2016 DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 PANTHER PTHR21021:SF19 59 72 4.1E-42 T 23-04-2016 DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 Pfam PF13581 Histidine kinase-like ATPase domain 696 800 1.2E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 Pfam PF08448 PAS fold 141 249 9.0E-21 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 SUPERFAMILY SSF55785 130 247 7.93E-16 T 23-04-2016 IPR000014 PAS domain DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 493 682 8.4E-47 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 PANTHER PTHR21021 441 691 4.1E-42 T 23-04-2016 DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 PANTHER PTHR21021 59 72 4.1E-42 T 23-04-2016 DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 SMART SM00091 9 77 11.0 T 23-04-2016 IPR000014 PAS domain DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 SMART SM00091 132 198 0.0011 T 23-04-2016 IPR000014 PAS domain DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 15 107 5.2E-6 T 23-04-2016 IPR000014 PAS domain DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 130 255 1.5E-5 T 23-04-2016 IPR000014 PAS domain DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 SMART SM00331 466 682 2.6E-27 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 SMART SM00065 275 445 0.0041 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 Pfam PF01590 GAF domain 351 435 2.7E-8 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 Gene3D G3DSA:3.30.450.20 129 248 2.7E-19 T 23-04-2016 DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 Gene3D G3DSA:3.30.450.20 14 114 6.1E-10 T 23-04-2016 DC74_RS10795 3a8b151641c7efe06e6b8e265706b822 833 Gene3D G3DSA:3.30.450.40 259 443 4.3E-34 T 23-04-2016 IPR029016 GAF domain-like DC74_RS03560 35d14b32b6c9bdb785828d884c519011 337 Gene3D G3DSA:3.30.2010.10 105 182 4.3E-17 T 23-04-2016 DC74_RS03560 35d14b32b6c9bdb785828d884c519011 337 Pfam PF01435 Peptidase family M48 124 190 2.2E-12 T 23-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DC74_RS03560 35d14b32b6c9bdb785828d884c519011 337 PANTHER PTHR22726 10 16 3.9E-12 T 23-04-2016 DC74_RS03560 35d14b32b6c9bdb785828d884c519011 337 PANTHER PTHR22726 99 210 3.9E-12 T 23-04-2016 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 Gene3D G3DSA:1.20.1250.20 33 215 1.4E-31 T 23-04-2016 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 Gene3D G3DSA:1.20.1250.20 290 443 3.4E-22 T 23-04-2016 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 Gene3D G3DSA:1.20.1250.20 519 546 3.4E-22 T 23-04-2016 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 PANTHER PTHR23501 21 454 9.5E-182 T 23-04-2016 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 PANTHER PTHR23501 475 591 9.5E-182 T 23-04-2016 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 Gene3D G3DSA:2.60.40.1120 769 847 1.0E-10 T 23-04-2016 IPR014766 Carboxypeptidase, regulatory domain DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 PANTHER PTHR23501:SF73 21 454 9.5E-182 T 23-04-2016 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 PANTHER PTHR23501:SF73 475 591 9.5E-182 T 23-04-2016 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 SUPERFAMILY SSF103473 270 442 2.49E-66 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 SUPERFAMILY SSF103473 30 221 2.49E-66 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 SUPERFAMILY SSF103473 518 544 2.49E-66 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 Pfam PF13620 Carboxypeptidase regulatory-like domain 602 679 5.5E-13 T 23-04-2016 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 Pfam PF13620 Carboxypeptidase regulatory-like domain 685 764 7.9E-13 T 23-04-2016 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 Pfam PF13620 Carboxypeptidase regulatory-like domain 769 846 5.0E-13 T 23-04-2016 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 SUPERFAMILY SSF49464 602 681 1.84E-13 T 23-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 Pfam PF07690 Major Facilitator Superfamily 33 432 2.0E-51 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 SUPERFAMILY SSF49478 770 829 2.98E-10 T 23-04-2016 DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 SUPERFAMILY SSF49464 684 768 1.84E-10 T 23-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 Gene3D G3DSA:2.60.40.1120 684 768 6.3E-12 T 23-04-2016 IPR014766 Carboxypeptidase, regulatory domain DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 Gene3D G3DSA:2.60.40.1120 602 679 3.2E-11 T 23-04-2016 IPR014766 Carboxypeptidase, regulatory domain DC74_RS04340 a18bc8ae4b69d79957cdc26c904b0579 852 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 29 441 2.0E-74 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS06665 3769dfa705003afe710c95071fddfe7d 264 SUPERFAMILY SSF56317 1 262 6.93E-64 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS06665 3769dfa705003afe710c95071fddfe7d 264 PANTHER PTHR23088 1 263 1.6E-72 T 23-04-2016 DC74_RS06665 3769dfa705003afe710c95071fddfe7d 264 Gene3D G3DSA:3.60.110.10 1 263 2.1E-69 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS06665 3769dfa705003afe710c95071fddfe7d 264 PANTHER PTHR23088:SF27 1 263 1.6E-72 T 23-04-2016 DC74_RS06665 3769dfa705003afe710c95071fddfe7d 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 254 1.7E-41 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS06665 3769dfa705003afe710c95071fddfe7d 264 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 138 158 - T 23-04-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site DC74_RS04390 9a8430e6e92572b05896ed262ad61bff 220 Pfam PF00702 haloacid dehalogenase-like hydrolase 91 193 6.9E-9 T 23-04-2016 DC74_RS04390 9a8430e6e92572b05896ed262ad61bff 220 PANTHER PTHR12725 1 194 1.3E-25 T 23-04-2016 DC74_RS04390 9a8430e6e92572b05896ed262ad61bff 220 SUPERFAMILY SSF56784 20 204 4.72E-29 T 23-04-2016 IPR023214 HAD-like domain DC74_RS04390 9a8430e6e92572b05896ed262ad61bff 220 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 116 195 7.5E-13 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS04390 9a8430e6e92572b05896ed262ad61bff 220 Gene3D G3DSA:3.40.50.1000 20 201 6.1E-29 T 23-04-2016 IPR023214 HAD-like domain DC74_RS23080 0566e3a875ab264ee7dcc73f65f1b661 201 SUPERFAMILY SSF46689 4 61 4.05E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS23080 0566e3a875ab264ee7dcc73f65f1b661 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 4.9E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS23080 0566e3a875ab264ee7dcc73f65f1b661 201 PANTHER PTHR30328:SF8 1 112 1.7E-12 T 23-04-2016 DC74_RS23080 0566e3a875ab264ee7dcc73f65f1b661 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 4.7E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS23080 0566e3a875ab264ee7dcc73f65f1b661 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 4.7E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS23080 0566e3a875ab264ee7dcc73f65f1b661 201 PANTHER PTHR30328 1 112 1.7E-12 T 23-04-2016 DC74_RS23080 0566e3a875ab264ee7dcc73f65f1b661 201 Gene3D G3DSA:1.10.357.10 4 199 2.9E-25 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS11745 7d9cef15b0c91a08672a5cda9834946a 320 Gene3D G3DSA:3.40.50.300 14 233 4.9E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11745 7d9cef15b0c91a08672a5cda9834946a 320 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS11745 7d9cef15b0c91a08672a5cda9834946a 320 SMART SM00382 43 221 2.9E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS11745 7d9cef15b0c91a08672a5cda9834946a 320 Pfam PF00005 ABC transporter 35 173 7.3E-24 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS11745 7d9cef15b0c91a08672a5cda9834946a 320 PANTHER PTHR24220:SF414 20 313 2.8E-141 T 23-04-2016 DC74_RS11745 7d9cef15b0c91a08672a5cda9834946a 320 PANTHER PTHR24220 20 313 2.8E-141 T 23-04-2016 DC74_RS11745 7d9cef15b0c91a08672a5cda9834946a 320 SUPERFAMILY SSF52540 15 233 1.56E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS31625 69d744215dd3db985a331dd5aeb9d44f 280 Pfam PF00795 Carbon-nitrogen hydrolase 6 261 6.2E-66 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS31625 69d744215dd3db985a331dd5aeb9d44f 280 PANTHER PTHR23088:SF11 1 280 3.5E-128 T 23-04-2016 DC74_RS31625 69d744215dd3db985a331dd5aeb9d44f 280 Gene3D G3DSA:3.60.110.10 4 278 2.4E-87 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS31625 69d744215dd3db985a331dd5aeb9d44f 280 SUPERFAMILY SSF56317 3 277 6.41E-80 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS31625 69d744215dd3db985a331dd5aeb9d44f 280 PANTHER PTHR23088 1 280 3.5E-128 T 23-04-2016 DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 SUPERFAMILY SSF51735 18 240 6.33E-60 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 159 187 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 Gene3D G3DSA:3.40.50.720 16 248 2.7E-69 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 7.01E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 172 191 7.01E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 7.01E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 18 207 0.0059 T 23-04-2016 DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 PANTHER PTHR24322 172 204 8.0E-56 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 PANTHER PTHR24322 22 154 8.0E-56 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 8.65E-30 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 8.65E-30 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 8.65E-30 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 8.65E-30 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 8.65E-30 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31490 955a3d9b19c868973cf5b61d8b8e0454 248 Pfam PF00106 short chain dehydrogenase 19 210 3.0E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 Gene3D G3DSA:3.30.565.10 321 487 7.2E-43 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 Pfam PF00672 HAMP domain 190 253 4.7E-16 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 SMART SM00304 275 327 40.0 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 SMART SM00304 205 257 5.8E-13 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 SMART SM00387 376 485 6.3E-35 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 377 484 1.3E-20 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 SUPERFAMILY SSF55874 323 486 1.14E-40 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 SUPERFAMILY SSF158472 205 253 6.93E-10 T 23-04-2016 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 4.2E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 425 4.2E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 482 4.2E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 439 4.2E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 Gene3D G3DSA:1.10.287.130 258 320 1.9E-14 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 PANTHER PTHR24423 4 10 1.5E-72 T 23-04-2016 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 PANTHER PTHR24423 199 491 1.5E-72 T 23-04-2016 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 Pfam PF00512 His Kinase A (phospho-acceptor) domain 267 333 7.8E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 SUPERFAMILY SSF47384 248 333 1.92E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS00505 611a7eb37f7bdc6edf6f2f85d1199bb1 491 SMART SM00388 265 334 1.1E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS00475 6f1f73ccaa882d7f5096ed635f167029 130 SUPERFAMILY SSF54593 1 127 2.55E-24 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS00475 6f1f73ccaa882d7f5096ed635f167029 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 125 3.7E-13 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS00475 6f1f73ccaa882d7f5096ed635f167029 130 Gene3D G3DSA:3.10.180.10 1 128 3.0E-22 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS00475 6f1f73ccaa882d7f5096ed635f167029 130 PANTHER PTHR36437 1 130 1.4E-77 T 23-04-2016 DC74_RS00475 6f1f73ccaa882d7f5096ed635f167029 130 PANTHER PTHR36437:SF1 1 130 1.4E-77 T 23-04-2016 DC74_RS20850 f278d46dca4318d98c9ffad3c1924a96 486 PANTHER PTHR30153 35 484 3.5E-206 T 23-04-2016 DC74_RS20850 f278d46dca4318d98c9ffad3c1924a96 486 Pfam PF00772 DnaB-like helicase N terminal domain 51 152 5.2E-37 T 23-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 DC74_RS20850 f278d46dca4318d98c9ffad3c1924a96 486 SMART SM00382 243 442 0.0014 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS20850 f278d46dca4318d98c9ffad3c1924a96 486 SUPERFAMILY SSF48024 49 160 6.02E-40 T 23-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 DC74_RS20850 f278d46dca4318d98c9ffad3c1924a96 486 Gene3D G3DSA:3.40.50.300 211 485 3.3E-119 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20850 f278d46dca4318d98c9ffad3c1924a96 486 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 51 484 5.8E-168 T 23-04-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 DC74_RS20850 f278d46dca4318d98c9ffad3c1924a96 486 Gene3D G3DSA:1.10.860.10 51 153 4.5E-42 T 23-04-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal DC74_RS20850 f278d46dca4318d98c9ffad3c1924a96 486 SUPERFAMILY SSF52540 224 475 2.92E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20850 f278d46dca4318d98c9ffad3c1924a96 486 Pfam PF03796 DnaB-like helicase C terminal domain 226 481 2.3E-108 T 23-04-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 DC74_RS23085 335bd3f33b6b1cf4b662cb93eee3651d 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 128 9.7E-7 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS23085 335bd3f33b6b1cf4b662cb93eee3651d 140 Gene3D G3DSA:3.10.180.10 10 131 1.4E-21 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS23085 335bd3f33b6b1cf4b662cb93eee3651d 140 PANTHER PTHR34309 1 130 2.0E-41 T 23-04-2016 DC74_RS23085 335bd3f33b6b1cf4b662cb93eee3651d 140 SUPERFAMILY SSF54593 9 136 5.24E-21 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS23085 335bd3f33b6b1cf4b662cb93eee3651d 140 PANTHER PTHR34309:SF2 1 130 2.0E-41 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 Pfam PF00403 Heavy-metal-associated domain 13 71 8.1E-14 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 168 753 6.7E-177 T 23-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 Pfam PF00702 haloacid dehalogenase-like hydrolase 445 665 4.5E-43 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 ProSitePatterns PS01229 Hypothetical cof family signature 2. 651 673 - T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 Gene3D G3DSA:3.40.1110.10 466 576 2.4E-20 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 SUPERFAMILY SSF56784 447 467 6.05E-55 T 23-04-2016 IPR023214 HAD-like domain DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 SUPERFAMILY SSF56784 506 751 6.05E-55 T 23-04-2016 IPR023214 HAD-like domain DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 Gene3D G3DSA:2.70.150.10 212 350 3.6E-29 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 214 754 6.3E-150 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 SUPERFAMILY SSF81653 255 349 2.62E-25 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 SUPERFAMILY SSF55008 5 73 1.44E-18 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 451 457 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 223 733 2.4E-84 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 SUPERFAMILY SSF81665 350 443 3.79E-12 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 SUPERFAMILY SSF81665 700 728 3.79E-12 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 SUPERFAMILY SSF81665 215 253 3.79E-12 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 Pfam PF00122 E1-E2 ATPase 222 440 2.6E-65 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 ProSitePatterns PS01047 Heavy-metal-associated domain. 15 43 - T 23-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PANTHER PTHR24093 10 761 1.0E-238 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 Gene3D G3DSA:3.40.50.1000 577 719 3.8E-49 T 23-04-2016 IPR023214 HAD-like domain DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 Gene3D G3DSA:3.40.50.1000 421 465 3.8E-49 T 23-04-2016 IPR023214 HAD-like domain DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 651 670 3.4E-23 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 449 463 3.4E-23 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 299 313 3.4E-23 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 596 606 3.4E-23 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 674 686 3.4E-23 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PANTHER PTHR24093:SF50 10 761 1.0E-238 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 Gene3D G3DSA:3.30.70.100 6 73 1.1E-22 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PRINTS PR00943 Copper-transporting ATPase signature 372 386 2.8E-9 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PRINTS PR00943 Copper-transporting ATPase signature 219 238 2.8E-9 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PRINTS PR00943 Copper-transporting ATPase signature 628 645 2.8E-9 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PRINTS PR00943 Copper-transporting ATPase signature 685 699 2.8E-9 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PRINTS PR00943 Copper-transporting ATPase signature 25 39 2.8E-9 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PRINTS PR00943 Copper-transporting ATPase signature 239 257 2.8E-9 T 23-04-2016 DC74_RS32790 bc82622f2baa07a8c913eb0511a8d763 761 PRINTS PR00943 Copper-transporting ATPase signature 432 447 2.8E-9 T 23-04-2016 DC74_RS00725 1230bc450aa9e6d4f41441d302a7e9fe 235 SUPERFAMILY SSF48498 83 155 8.56E-9 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS00725 1230bc450aa9e6d4f41441d302a7e9fe 235 Gene3D G3DSA:1.10.357.10 5 174 1.1E-32 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS00725 1230bc450aa9e6d4f41441d302a7e9fe 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.8E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00725 1230bc450aa9e6d4f41441d302a7e9fe 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.8E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00725 1230bc450aa9e6d4f41441d302a7e9fe 235 PANTHER PTHR30055 1 161 1.2E-20 T 23-04-2016 DC74_RS00725 1230bc450aa9e6d4f41441d302a7e9fe 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 5.0E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00725 1230bc450aa9e6d4f41441d302a7e9fe 235 SUPERFAMILY SSF46689 4 74 1.89E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02140 a2f719636d49653c42993a234385a981 1086 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 265 675 2.0E-109 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS02140 a2f719636d49653c42993a234385a981 1086 SUPERFAMILY SSF53474 787 1079 1.81E-37 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02140 a2f719636d49653c42993a234385a981 1086 Gene3D G3DSA:1.10.1200.10 761 824 6.9E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS02140 a2f719636d49653c42993a234385a981 1086 SMART SM00823 Phosphopantetheine attachment site 758 825 0.0084 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS02140 a2f719636d49653c42993a234385a981 1086 Gene3D G3DSA:3.40.50.980 403 551 6.2E-44 T 23-04-2016 DC74_RS02140 a2f719636d49653c42993a234385a981 1086 SUPERFAMILY SSF52777 5 208 2.0E-15 T 23-04-2016 DC74_RS02140 a2f719636d49653c42993a234385a981 1086 Pfam PF13193 AMP-binding enzyme C-terminal domain 660 731 2.1E-9 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS02140 a2f719636d49653c42993a234385a981 1086 SUPERFAMILY SSF56801 214 771 1.83E-144 T 23-04-2016 DC74_RS02140 a2f719636d49653c42993a234385a981 1086 Gene3D G3DSA:3.40.50.980 237 402 1.8E-46 T 23-04-2016 DC74_RS02140 a2f719636d49653c42993a234385a981 1086 Gene3D G3DSA:3.40.50.1820 844 1078 7.7E-21 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02140 a2f719636d49653c42993a234385a981 1086 Pfam PF00501 AMP-binding enzyme 244 651 6.5E-87 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS02140 a2f719636d49653c42993a234385a981 1086 Gene3D G3DSA:3.30.300.30 647 760 6.3E-35 T 23-04-2016 DC74_RS02140 a2f719636d49653c42993a234385a981 1086 PANTHER PTHR24095:SF137 42 822 1.0E-163 T 23-04-2016 DC74_RS02140 a2f719636d49653c42993a234385a981 1086 Gene3D G3DSA:2.30.38.10 562 641 1.1E-20 T 23-04-2016 DC74_RS02140 a2f719636d49653c42993a234385a981 1086 Pfam PF00975 Thioesterase domain 845 1068 3.1E-15 T 23-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 DC74_RS02140 a2f719636d49653c42993a234385a981 1086 Pfam PF00550 Phosphopantetheine attachment site 760 821 5.6E-9 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS02140 a2f719636d49653c42993a234385a981 1086 ProSitePatterns PS00455 Putative AMP-binding domain signature. 393 404 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS02140 a2f719636d49653c42993a234385a981 1086 PANTHER PTHR24095 42 822 1.0E-163 T 23-04-2016 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 PANTHER PTHR11632:SF56 4 301 0.0 T 23-04-2016 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 PANTHER PTHR11632:SF56 318 632 0.0 T 23-04-2016 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 Gene3D G3DSA:3.50.50.60 385 451 4.1E-106 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 Gene3D G3DSA:3.50.50.60 3 249 4.1E-106 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 Pfam PF02910 Fumarate reductase flavoprotein C-term 489 588 1.1E-22 T 23-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 PANTHER PTHR11632 4 301 0.0 T 23-04-2016 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 PANTHER PTHR11632 318 632 0.0 T 23-04-2016 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 Pfam PF00890 FAD binding domain 10 430 1.8E-94 T 23-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 8.3E-9 T 23-04-2016 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 394 416 8.3E-9 T 23-04-2016 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 Gene3D G3DSA:1.20.58.100 468 575 4.0E-31 T 23-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 SUPERFAMILY SSF56425 243 389 3.14E-34 T 23-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 PIRSF PIRSF000171 1 597 1.9E-37 T 23-04-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 Gene3D G3DSA:3.90.700.10 250 383 7.9E-36 T 23-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 SUPERFAMILY SSF46977 483 637 1.83E-36 T 23-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 SUPERFAMILY SSF51905 393 470 4.42E-72 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS25785 eabeea21956a14b5cf97201c569dbb28 640 SUPERFAMILY SSF51905 6 270 4.42E-72 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS05505 37d601430b7d25310e54e3d9d117992e 424 SUPERFAMILY SSF53187 83 346 6.65E-36 T 23-04-2016 DC74_RS05505 37d601430b7d25310e54e3d9d117992e 424 PIRSF PIRSF015244 1 424 4.4E-211 T 23-04-2016 IPR012353 Uncharacterised conserved protein UCP01524, polysaccharide biosynthesis aminopeptidase-like DC74_RS05505 37d601430b7d25310e54e3d9d117992e 424 Pfam PF09940 Domain of unknown function (DUF2172) 59 150 2.1E-38 T 23-04-2016 IPR032610 Domain of unknown function DUF2172 DC74_RS05505 37d601430b7d25310e54e3d9d117992e 424 Gene3D G3DSA:3.40.630.10 162 338 4.9E-12 T 23-04-2016 DC74_RS05505 37d601430b7d25310e54e3d9d117992e 424 Pfam PF16221 winged helix-turn-helix 348 423 6.8E-32 T 23-04-2016 IPR032622 UCP01524, winged helix-turn-helix domain DC74_RS05505 37d601430b7d25310e54e3d9d117992e 424 Pfam PF16254 Domain of unknown function (DUF4910) 9 346 4.9E-114 T 23-04-2016 IPR032589 Domain of unknown function DUF4910 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 Gene3D G3DSA:2.20.28.20 142 173 4.2E-18 T 23-04-2016 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 565 36.765 T 23-04-2016 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 3.3E-28 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 299 314 3.3E-28 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 3.3E-28 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 258 269 3.3E-28 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 3.3E-28 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 393 404 3.3E-28 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 PANTHER PTHR11946 5 570 1.0E-203 T 23-04-2016 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 SUPERFAMILY SSF57770 139 172 1.96E-11 T 23-04-2016 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 Gene3D G3DSA:3.40.50.620 4 141 6.8E-79 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 Gene3D G3DSA:3.40.50.620 181 388 6.8E-79 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 PANTHER PTHR11946:SF86 5 570 1.0E-203 T 23-04-2016 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 Gene3D G3DSA:1.10.730.10 389 554 2.6E-38 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 SUPERFAMILY SSF52374 4 138 7.41E-79 T 23-04-2016 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 SUPERFAMILY SSF52374 174 393 7.41E-79 T 23-04-2016 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 Pfam PF09334 tRNA synthetases class I (M) 4 406 1.4E-148 T 23-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 535 6.9E-143 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 DC74_RS20245 0e38eab682b5d09fb0236ef1861f2b33 571 SUPERFAMILY SSF47323 394 554 2.43E-33 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS32680 1bcad0d1980b207b217e59112170bad8 176 SUPERFAMILY SSF51283 2 167 5.89E-24 T 23-04-2016 IPR029054 dUTPase-like DC74_RS32680 1bcad0d1980b207b217e59112170bad8 176 PANTHER PTHR11241 2 169 3.0E-18 T 23-04-2016 DC74_RS32680 1bcad0d1980b207b217e59112170bad8 176 PANTHER PTHR11241:SF1 2 169 3.0E-18 T 23-04-2016 DC74_RS32680 1bcad0d1980b207b217e59112170bad8 176 Gene3D G3DSA:2.70.40.10 2 167 2.8E-24 T 23-04-2016 IPR029054 dUTPase-like DC74_RS10470 f715310f3240546423b7560cd0db73e9 231 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 202 1.1E-47 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS10470 f715310f3240546423b7560cd0db73e9 231 PANTHER PTHR23029 1 228 3.3E-115 T 23-04-2016 DC74_RS10470 f715310f3240546423b7560cd0db73e9 231 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 204 3.5E-94 T 23-04-2016 IPR022492 Phosphomutase MSMEG4193, putative DC74_RS10470 f715310f3240546423b7560cd0db73e9 231 SMART SM00855 3 162 4.9E-21 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS10470 f715310f3240546423b7560cd0db73e9 231 Gene3D G3DSA:3.40.50.1240 1 212 3.7E-48 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS10470 f715310f3240546423b7560cd0db73e9 231 SUPERFAMILY SSF53254 1 210 2.12E-45 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS10470 f715310f3240546423b7560cd0db73e9 231 PANTHER PTHR23029:SF25 1 228 3.3E-115 T 23-04-2016 DC74_RS27805 30c6ccfc586608773660086c00d37a63 427 Pfam PF07690 Major Facilitator Superfamily 23 339 2.7E-23 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS27805 30c6ccfc586608773660086c00d37a63 427 SUPERFAMILY SSF103473 11 412 4.45E-52 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS27805 30c6ccfc586608773660086c00d37a63 427 Gene3D G3DSA:1.20.1250.20 226 410 4.5E-24 T 23-04-2016 DC74_RS27805 30c6ccfc586608773660086c00d37a63 427 Gene3D G3DSA:1.20.1250.20 15 198 1.4E-18 T 23-04-2016 DC74_RS37570 96d6cc290959347c6dad552efc282d50 393 PANTHER PTHR24023 63 390 5.2E-22 T 23-04-2016 DC74_RS37570 96d6cc290959347c6dad552efc282d50 393 SUPERFAMILY SSF89796 11 391 1.96E-116 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS37570 96d6cc290959347c6dad552efc282d50 393 Gene3D G3DSA:3.30.1540.10 232 312 7.6E-26 T 23-04-2016 DC74_RS37570 96d6cc290959347c6dad552efc282d50 393 Pfam PF02515 CoA-transferase family III 14 380 2.0E-104 T 23-04-2016 IPR003673 CoA-transferase family III GO:0003824 DC74_RS37570 96d6cc290959347c6dad552efc282d50 393 Gene3D G3DSA:3.40.50.10540 313 390 1.4E-95 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS37570 96d6cc290959347c6dad552efc282d50 393 Gene3D G3DSA:3.40.50.10540 12 224 1.4E-95 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS37570 96d6cc290959347c6dad552efc282d50 393 PANTHER PTHR24023:SF593 63 390 5.2E-22 T 23-04-2016 DC74_RS35170 b971eb38c615cc2d1e34c79701d35b74 367 Pfam PF01757 Acyltransferase family 1 308 4.3E-21 T 23-04-2016 IPR002656 Acyltransferase 3 GO:0016747 DC74_RS35170 b971eb38c615cc2d1e34c79701d35b74 367 PANTHER PTHR23028 1 332 5.6E-79 T 23-04-2016 DC74_RS35170 b971eb38c615cc2d1e34c79701d35b74 367 PANTHER PTHR23028:SF79 1 332 5.6E-79 T 23-04-2016 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 Gene3D G3DSA:1.10.8.60 731 817 4.1E-33 T 23-04-2016 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 329 1.1E-12 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 Gene3D G3DSA:3.40.50.300 702 730 1.5E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 Gene3D G3DSA:3.40.50.300 494 667 1.5E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 PANTHER PTHR11638:SF18 1 830 0.0 T 23-04-2016 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 SMART SM00382 204 348 5.9E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 SMART SM00382 541 689 1.1E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 SMART SM01086 719 812 1.9E-38 T 23-04-2016 IPR019489 Clp ATPase, C-terminal DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 Pfam PF02151 UvrB/uvrC motif 421 453 1.8E-5 T 23-04-2016 IPR001943 UVR domain GO:0005515 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 Gene3D G3DSA:1.10.8.60 350 432 3.9E-34 T 23-04-2016 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 719 798 7.6E-27 T 23-04-2016 IPR019489 Clp ATPase, C-terminal DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 SUPERFAMILY SSF52540 167 450 5.75E-74 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 SUPERFAMILY SSF52540 490 802 3.7E-80 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 Pfam PF07724 AAA domain (Cdc48 subfamily) 541 712 5.5E-54 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 666 6.2E-40 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 545 563 6.2E-40 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 590 608 6.2E-40 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 619 637 6.2E-40 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 3.2E-19 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 4.5E-17 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 SUPERFAMILY SSF81923 3 144 3.63E-33 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 23-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 PANTHER PTHR11638 1 830 0.0 T 23-04-2016 DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 Gene3D G3DSA:3.40.50.300 167 347 4.3E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22605 0b7a12bbc1b7d7a8710763d631abfb24 841 Gene3D G3DSA:1.10.1780.10 1 143 3.1E-54 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 PANTHER PTHR24423 186 500 6.9E-76 T 23-04-2016 DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 475 1.2E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 493 1.2E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 430 1.2E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 494 1.8E-21 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 Pfam PF00672 HAMP domain 166 239 2.1E-10 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 Gene3D G3DSA:3.30.565.10 306 496 1.1E-40 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 SUPERFAMILY SSF47384 243 321 4.9E-20 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 SMART SM00387 365 496 2.2E-35 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 Gene3D G3DSA:1.10.287.130 246 305 2.8E-20 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 320 6.8E-20 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 SMART SM00388 253 320 7.3E-24 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 SUPERFAMILY SSF55874 309 495 5.5E-38 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21495 3b0c553e28d562d48c3987076d1aabc5 500 SMART SM00304 183 245 6.2E-5 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS10685 868450c0e4db3abdc7fd2ea2dec5fb8a 189 PANTHER PTHR30204 3 141 5.8E-73 T 23-04-2016 DC74_RS10685 868450c0e4db3abdc7fd2ea2dec5fb8a 189 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 2.1E-12 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS10685 868450c0e4db3abdc7fd2ea2dec5fb8a 189 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 2.1E-12 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS10685 868450c0e4db3abdc7fd2ea2dec5fb8a 189 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 2.1E-12 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS10685 868450c0e4db3abdc7fd2ea2dec5fb8a 189 Pfam PF00376 MerR family regulatory protein 12 48 6.3E-11 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS10685 868450c0e4db3abdc7fd2ea2dec5fb8a 189 Gene3D G3DSA:1.10.1660.10 11 64 1.1E-18 T 23-04-2016 DC74_RS10685 868450c0e4db3abdc7fd2ea2dec5fb8a 189 Pfam PF09278 MerR, DNA binding 53 118 9.6E-18 T 23-04-2016 IPR015358 Transcription regulator MerR, DNA binding DC74_RS10685 868450c0e4db3abdc7fd2ea2dec5fb8a 189 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 10 149 2.1E-68 T 23-04-2016 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 DC74_RS10685 868450c0e4db3abdc7fd2ea2dec5fb8a 189 SUPERFAMILY SSF46955 11 133 8.79E-27 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS10685 868450c0e4db3abdc7fd2ea2dec5fb8a 189 Gene3D G3DSA:1.10.1660.10 65 144 4.1E-16 T 23-04-2016 DC74_RS10685 868450c0e4db3abdc7fd2ea2dec5fb8a 189 SMART SM00422 11 79 4.3E-24 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS10685 868450c0e4db3abdc7fd2ea2dec5fb8a 189 PANTHER PTHR30204:SF0 3 141 5.8E-73 T 23-04-2016 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 DC74_RS39900 8e1ad69ffd4e8055056fe478d8d15a01 326 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 259 301 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS39900 8e1ad69ffd4e8055056fe478d8d15a01 326 Pfam PF12833 Helix-turn-helix domain 228 306 6.9E-22 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS39900 8e1ad69ffd4e8055056fe478d8d15a01 326 SUPERFAMILY SSF52317 4 188 1.79E-45 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS39900 8e1ad69ffd4e8055056fe478d8d15a01 326 Gene3D G3DSA:1.10.10.60 260 308 5.2E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39900 8e1ad69ffd4e8055056fe478d8d15a01 326 Pfam PF01965 DJ-1/PfpI family 4 167 1.2E-18 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS39900 8e1ad69ffd4e8055056fe478d8d15a01 326 PANTHER PTHR11019:SF68 1 313 1.2E-106 T 23-04-2016 DC74_RS39900 8e1ad69ffd4e8055056fe478d8d15a01 326 SUPERFAMILY SSF46689 259 309 1.52E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39900 8e1ad69ffd4e8055056fe478d8d15a01 326 SMART SM00342 222 305 6.7E-27 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS39900 8e1ad69ffd4e8055056fe478d8d15a01 326 Gene3D G3DSA:3.40.50.880 5 201 4.0E-50 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS39900 8e1ad69ffd4e8055056fe478d8d15a01 326 PANTHER PTHR11019 1 313 1.2E-106 T 23-04-2016 DC74_RS39900 8e1ad69ffd4e8055056fe478d8d15a01 326 SUPERFAMILY SSF46689 212 256 5.04E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39900 8e1ad69ffd4e8055056fe478d8d15a01 326 Gene3D G3DSA:1.10.10.60 215 259 3.8E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS16190 5fd06693e64341963b9bbfebbe245754 357 Pfam PF00005 ABC transporter 19 161 2.3E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS16190 5fd06693e64341963b9bbfebbe245754 357 Gene3D G3DSA:3.40.50.300 1 236 2.3E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16190 5fd06693e64341963b9bbfebbe245754 357 Pfam PF08402 TOBE domain 273 346 3.5E-11 T 23-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 DC74_RS16190 5fd06693e64341963b9bbfebbe245754 357 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS16190 5fd06693e64341963b9bbfebbe245754 357 SMART SM00382 28 258 9.0E-18 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS16190 5fd06693e64341963b9bbfebbe245754 357 PANTHER PTHR24220 2 247 3.9E-109 T 23-04-2016 DC74_RS16190 5fd06693e64341963b9bbfebbe245754 357 SUPERFAMILY SSF52540 1 244 2.05E-81 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16190 5fd06693e64341963b9bbfebbe245754 357 PANTHER PTHR24220:SF151 2 247 3.9E-109 T 23-04-2016 DC74_RS16190 5fd06693e64341963b9bbfebbe245754 357 SUPERFAMILY SSF50331 238 347 6.17E-13 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal DC74_RS36375 a105bbaa53e6bc38a6b18d0b26081637 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 212 6.7E-38 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS36375 a105bbaa53e6bc38a6b18d0b26081637 259 SUPERFAMILY SSF52096 6 233 1.76E-56 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS36375 a105bbaa53e6bc38a6b18d0b26081637 259 Gene3D G3DSA:3.90.226.10 9 228 5.4E-56 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS36375 a105bbaa53e6bc38a6b18d0b26081637 259 PANTHER PTHR11941 8 226 3.2E-48 T 23-04-2016 DC74_RS13755 51c45abef648863a51b0feaf8ad394b7 151 Pfam PF00293 NUDIX domain 30 145 5.1E-16 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS13755 51c45abef648863a51b0feaf8ad394b7 151 PANTHER PTHR22769 19 147 2.8E-22 T 23-04-2016 DC74_RS13755 51c45abef648863a51b0feaf8ad394b7 151 ProSitePatterns PS00893 Nudix box signature. 62 83 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS13755 51c45abef648863a51b0feaf8ad394b7 151 SUPERFAMILY SSF55811 20 145 1.62E-24 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS13755 51c45abef648863a51b0feaf8ad394b7 151 Gene3D G3DSA:3.90.79.10 28 141 1.3E-23 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS35905 7ce02a52b98dd01469b3f08186a21dea 356 PANTHER PTHR11019 139 344 3.5E-37 T 23-04-2016 DC74_RS35905 7ce02a52b98dd01469b3f08186a21dea 356 PANTHER PTHR11019:SF52 139 344 3.5E-37 T 23-04-2016 DC74_RS35905 7ce02a52b98dd01469b3f08186a21dea 356 Gene3D G3DSA:1.10.10.60 289 337 4.7E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS35905 7ce02a52b98dd01469b3f08186a21dea 356 SUPERFAMILY SSF46689 289 336 4.48E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS35905 7ce02a52b98dd01469b3f08186a21dea 356 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 305 320 8.1E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS35905 7ce02a52b98dd01469b3f08186a21dea 356 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 320 336 8.1E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS35905 7ce02a52b98dd01469b3f08186a21dea 356 Pfam PF12833 Helix-turn-helix domain 260 336 2.2E-16 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS35905 7ce02a52b98dd01469b3f08186a21dea 356 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 22 206 2.6E-48 T 23-04-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal DC74_RS35905 7ce02a52b98dd01469b3f08186a21dea 356 SMART SM00342 253 336 7.6E-18 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS05680 d68200df59e23fbdba8f1492f539f4ab 384 Pfam PF13343 Bacterial extracellular solute-binding protein 117 339 3.5E-33 T 23-04-2016 DC74_RS05680 d68200df59e23fbdba8f1492f539f4ab 384 PANTHER PTHR30006:SF10 54 323 1.3E-31 T 23-04-2016 DC74_RS05680 d68200df59e23fbdba8f1492f539f4ab 384 PANTHER PTHR30006 54 323 1.3E-31 T 23-04-2016 DC74_RS05680 d68200df59e23fbdba8f1492f539f4ab 384 Gene3D G3DSA:3.40.190.10 168 308 2.1E-22 T 23-04-2016 DC74_RS05680 d68200df59e23fbdba8f1492f539f4ab 384 SUPERFAMILY SSF53850 63 346 2.96E-46 T 23-04-2016 DC74_RS05680 d68200df59e23fbdba8f1492f539f4ab 384 Gene3D G3DSA:3.40.190.10 309 353 8.9E-26 T 23-04-2016 DC74_RS05680 d68200df59e23fbdba8f1492f539f4ab 384 Gene3D G3DSA:3.40.190.10 13 167 8.9E-26 T 23-04-2016 DC74_RS38130 bd1967e36e85b59fed0f6797959c32f2 322 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 36 289 8.0E-61 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS38130 bd1967e36e85b59fed0f6797959c32f2 322 PANTHER PTHR10314:SF17 5 320 2.3E-55 T 23-04-2016 DC74_RS38130 bd1967e36e85b59fed0f6797959c32f2 322 PANTHER PTHR10314 5 320 2.3E-55 T 23-04-2016 DC74_RS38130 bd1967e36e85b59fed0f6797959c32f2 322 SUPERFAMILY SSF53686 23 318 2.36E-64 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS38130 bd1967e36e85b59fed0f6797959c32f2 322 Gene3D G3DSA:3.40.50.1100 74 319 1.2E-52 T 23-04-2016 DC74_RS38130 bd1967e36e85b59fed0f6797959c32f2 322 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 44 57 - T 23-04-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 DC74_RS13095 a80a90e384803b9c8e324cc35245bcb1 418 Gene3D G3DSA:3.50.50.60 189 256 1.0E-34 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS13095 a80a90e384803b9c8e324cc35245bcb1 418 Gene3D G3DSA:3.50.50.60 8 46 1.0E-34 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS13095 a80a90e384803b9c8e324cc35245bcb1 418 Gene3D G3DSA:3.50.50.60 363 406 1.0E-34 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS13095 a80a90e384803b9c8e324cc35245bcb1 418 Pfam PF13450 NAD(P)-binding Rossmann-like domain 12 61 2.3E-12 T 23-04-2016 DC74_RS13095 a80a90e384803b9c8e324cc35245bcb1 418 PRINTS PR00419 Adrenodoxin reductase family signature 9 31 5.2E-7 T 23-04-2016 DC74_RS13095 a80a90e384803b9c8e324cc35245bcb1 418 PRINTS PR00419 Adrenodoxin reductase family signature 32 45 5.2E-7 T 23-04-2016 DC74_RS13095 a80a90e384803b9c8e324cc35245bcb1 418 PANTHER PTHR10742 3 411 2.5E-27 T 23-04-2016 DC74_RS13095 a80a90e384803b9c8e324cc35245bcb1 418 SUPERFAMILY SSF51905 8 266 7.56E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS13095 a80a90e384803b9c8e324cc35245bcb1 418 SUPERFAMILY SSF51905 355 402 7.56E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS13095 a80a90e384803b9c8e324cc35245bcb1 418 Pfam PF01593 Flavin containing amine oxidoreductase 123 400 3.8E-21 T 23-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 DC74_RS16455 cde7ee7e8c40924884c3e1ddfecff149 155 PANTHER PTHR22769:SF42 6 145 1.6E-29 T 23-04-2016 DC74_RS16455 cde7ee7e8c40924884c3e1ddfecff149 155 PANTHER PTHR22769 6 145 1.6E-29 T 23-04-2016 DC74_RS16455 cde7ee7e8c40924884c3e1ddfecff149 155 Gene3D G3DSA:3.90.79.10 8 147 2.2E-36 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS16455 cde7ee7e8c40924884c3e1ddfecff149 155 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS16455 cde7ee7e8c40924884c3e1ddfecff149 155 Pfam PF00293 NUDIX domain 19 146 1.6E-21 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS16455 cde7ee7e8c40924884c3e1ddfecff149 155 SUPERFAMILY SSF55811 4 149 3.38E-37 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS16455 cde7ee7e8c40924884c3e1ddfecff149 155 PRINTS PR00502 NUDIX hydrolase family signature 44 58 1.6E-5 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS16455 cde7ee7e8c40924884c3e1ddfecff149 155 PRINTS PR00502 NUDIX hydrolase family signature 58 73 1.6E-5 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS14430 e138c411dbc8248329a1596d59e6dc71 210 Gene3D G3DSA:3.40.50.150 33 159 3.2E-17 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14430 e138c411dbc8248329a1596d59e6dc71 210 SUPERFAMILY SSF53335 22 187 3.59E-22 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14430 e138c411dbc8248329a1596d59e6dc71 210 Pfam PF08241 Methyltransferase domain 56 152 1.1E-9 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS05820 aceca20bf3b35e9aa09d8e537327b195 301 SMART SM00829 10 299 9.4E-12 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS05820 aceca20bf3b35e9aa09d8e537327b195 301 PANTHER PTHR11695 15 301 4.6E-55 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS05820 aceca20bf3b35e9aa09d8e537327b195 301 PANTHER PTHR11695:SF509 15 301 4.6E-55 T 23-04-2016 DC74_RS05820 aceca20bf3b35e9aa09d8e537327b195 301 SUPERFAMILY SSF50129 2 138 9.13E-33 T 23-04-2016 IPR011032 GroES-like DC74_RS05820 aceca20bf3b35e9aa09d8e537327b195 301 Gene3D G3DSA:3.90.180.10 2 192 1.2E-43 T 23-04-2016 IPR011032 GroES-like DC74_RS05820 aceca20bf3b35e9aa09d8e537327b195 301 SUPERFAMILY SSF51735 117 238 4.51E-22 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05820 aceca20bf3b35e9aa09d8e537327b195 301 Pfam PF13602 Zinc-binding dehydrogenase 190 299 6.5E-12 T 23-04-2016 DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PANTHER PTHR24322:SF390 11 140 1.0E-48 T 23-04-2016 DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PANTHER PTHR24322:SF390 156 187 1.0E-48 T 23-04-2016 DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PANTHER PTHR24322 11 140 1.0E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PANTHER PTHR24322 156 187 1.0E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 6.4E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.4E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 6.4E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 6.4E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 6.4E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 6.4E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.2E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.2E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.2E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 197 0.0018 T 23-04-2016 DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 Gene3D G3DSA:3.40.50.720 3 249 1.7E-78 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 SUPERFAMILY SSF51735 6 250 3.78E-75 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39645 264dacc12eb9c4560912d78fce242ca0 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 247 1.9E-56 T 23-04-2016 DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.1E-36 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.1E-36 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.1E-36 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.1E-36 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.1E-36 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.1E-36 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 254 5.2E-51 T 23-04-2016 DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 Gene3D G3DSA:3.40.50.720 11 255 2.1E-70 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 SUPERFAMILY SSF51735 14 255 7.3E-70 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 6.8E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 6.8E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 6.8E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 PANTHER PTHR24322 165 195 4.4E-37 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04580 df6918f644058371172b76b8a3d94cca 277 PANTHER PTHR24322 19 149 4.4E-37 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18840 f0445bf70df532892480487780c2d557 150 PANTHER PTHR13078:SF52 5 147 2.4E-36 T 23-04-2016 DC74_RS18840 f0445bf70df532892480487780c2d557 150 PANTHER PTHR13078 5 147 2.4E-36 T 23-04-2016 DC74_RS18840 f0445bf70df532892480487780c2d557 150 SUPERFAMILY SSF54637 7 147 4.8E-40 T 23-04-2016 IPR029069 HotDog domain DC74_RS18840 f0445bf70df532892480487780c2d557 150 Gene3D G3DSA:3.10.129.10 1 148 1.5E-39 T 23-04-2016 IPR029069 HotDog domain DC74_RS18840 f0445bf70df532892480487780c2d557 150 PIRSF PIRSF018072 1 150 1.0E-61 T 23-04-2016 IPR016709 Uncharacterised protein family UPF0336 DC74_RS18840 f0445bf70df532892480487780c2d557 150 Pfam PF13452 N-terminal half of MaoC dehydratase 7 137 4.1E-38 T 23-04-2016 DC74_RS18840 f0445bf70df532892480487780c2d557 150 Hamap MF_00799 UPF0336 protein . 1 148 37.305 T 23-04-2016 IPR016709 Uncharacterised protein family UPF0336 DC74_RS28585 e7e46f6706b9f0cb23f0c2fb36691fa1 250 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 43 248 1.3E-49 T 23-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28585 e7e46f6706b9f0cb23f0c2fb36691fa1 250 PANTHER PTHR20836 1 250 6.1E-78 T 23-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28585 e7e46f6706b9f0cb23f0c2fb36691fa1 250 Gene3D G3DSA:3.30.360.10 125 216 4.8E-32 T 23-04-2016 DC74_RS28585 e7e46f6706b9f0cb23f0c2fb36691fa1 250 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 130 147 - T 23-04-2016 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28585 e7e46f6706b9f0cb23f0c2fb36691fa1 250 SUPERFAMILY SSF51735 4 135 3.23E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS28585 e7e46f6706b9f0cb23f0c2fb36691fa1 250 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 111 246 1.0E-26 T 23-04-2016 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28585 e7e46f6706b9f0cb23f0c2fb36691fa1 250 Gene3D G3DSA:3.40.50.720 2 124 2.2E-42 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS28585 e7e46f6706b9f0cb23f0c2fb36691fa1 250 PIRSF PIRSF000161 2 250 7.0E-60 T 23-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28585 e7e46f6706b9f0cb23f0c2fb36691fa1 250 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 108 1.6E-23 T 23-04-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28585 e7e46f6706b9f0cb23f0c2fb36691fa1 250 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 248 28.708 T 23-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28585 e7e46f6706b9f0cb23f0c2fb36691fa1 250 SUPERFAMILY SSF55347 109 217 2.4E-38 T 23-04-2016 DC74_RS05410 e8365fd21451f936a86ce1191601f917 385 SUPERFAMILY SSF54909 53 372 2.68E-51 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS05410 e8365fd21451f936a86ce1191601f917 385 PANTHER PTHR30521 41 384 4.9E-31 T 23-04-2016 DC74_RS05410 e8365fd21451f936a86ce1191601f917 385 Pfam PF04261 Dyp-type peroxidase family 57 372 1.5E-45 T 23-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- DC74_RS05410 e8365fd21451f936a86ce1191601f917 385 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 57 372 1.2E-46 T 23-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- DC74_RS05410 e8365fd21451f936a86ce1191601f917 385 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 8 31 4.4E-5 T 23-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal DC74_RS05410 e8365fd21451f936a86ce1191601f917 385 PANTHER PTHR30521:SF4 41 384 4.9E-31 T 23-04-2016 DC74_RS31155 6cfd9af0b51c6622de1a9757ecf21fc3 300 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 2 167 8.1E-45 T 23-04-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DC74_RS31155 6cfd9af0b51c6622de1a9757ecf21fc3 300 Gene3D G3DSA:3.30.43.10 2 52 7.4E-15 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS31155 6cfd9af0b51c6622de1a9757ecf21fc3 300 SUPERFAMILY SSF55447 173 285 2.35E-19 T 23-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal DC74_RS31155 6cfd9af0b51c6622de1a9757ecf21fc3 300 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 173 279 1.4E-10 T 23-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal DC74_RS31155 6cfd9af0b51c6622de1a9757ecf21fc3 300 Gene3D G3DSA:3.30.390.50 173 284 3.3E-31 T 23-04-2016 DC74_RS31155 6cfd9af0b51c6622de1a9757ecf21fc3 300 PANTHER PTHR11908:SF68 1 284 4.0E-102 T 23-04-2016 DC74_RS31155 6cfd9af0b51c6622de1a9757ecf21fc3 300 SUPERFAMILY SSF56176 2 166 1.89E-46 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS31155 6cfd9af0b51c6622de1a9757ecf21fc3 300 Gene3D G3DSA:3.30.465.10 53 167 4.8E-32 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS31155 6cfd9af0b51c6622de1a9757ecf21fc3 300 PANTHER PTHR11908 1 284 4.0E-102 T 23-04-2016 DC74_RS31155 6cfd9af0b51c6622de1a9757ecf21fc3 300 SMART SM01092 172 282 2.2E-18 T 23-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal DC74_RS03490 398b99e013072aef77e4ae723b092fae 280 Gene3D G3DSA:2.40.10.10 60 157 4.5E-5 T 23-04-2016 DC74_RS03490 398b99e013072aef77e4ae723b092fae 280 SUPERFAMILY SSF50494 50 254 3.03E-12 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS09635 58167fa03394b00356e8b160a07d701d 303 Gene3D G3DSA:3.20.20.70 33 169 8.4E-47 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS09635 58167fa03394b00356e8b160a07d701d 303 Gene3D G3DSA:3.20.20.70 201 287 8.4E-47 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS09635 58167fa03394b00356e8b160a07d701d 303 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 18 303 7.5E-142 T 23-04-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 DC74_RS09635 58167fa03394b00356e8b160a07d701d 303 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 13 303 51.778 T 23-04-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 DC74_RS09635 58167fa03394b00356e8b160a07d701d 303 Pfam PF01680 SOR/SNZ family 16 221 2.3E-106 T 23-04-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 DC74_RS09635 58167fa03394b00356e8b160a07d701d 303 SUPERFAMILY SSF51366 27 274 7.06E-61 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 DC74_RS09635 58167fa03394b00356e8b160a07d701d 303 ProSitePatterns PS01235 PdxS/SNZ family signature. 214 232 - T 23-04-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 DC74_RS09635 58167fa03394b00356e8b160a07d701d 303 PANTHER PTHR31829 11 303 1.2E-217 T 23-04-2016 DC74_RS09635 58167fa03394b00356e8b160a07d701d 303 PIRSF PIRSF029271 4 303 8.1E-151 T 23-04-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 PANTHER PTHR32060 1 418 0.0 T 23-04-2016 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 SUPERFAMILY SSF69304 11 270 4.97E-23 T 23-04-2016 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 Gene3D G3DSA:2.130.10.10 346 685 2.4E-86 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 Gene3D G3DSA:2.130.10.10 261 292 2.4E-86 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 PANTHER PTHR32060 886 1126 0.0 T 23-04-2016 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 Gene3D G3DSA:3.30.750.44 694 764 1.6E-30 T 23-04-2016 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 PANTHER PTHR32060:SF12 435 866 0.0 T 23-04-2016 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 SMART SM00245 883 1075 7.0E-11 T 23-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 PANTHER PTHR32060:SF12 1 418 0.0 T 23-04-2016 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 SUPERFAMILY SSF50156 779 855 1.37E-12 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 SUPERFAMILY SSF52096 694 773 1.82E-62 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 SUPERFAMILY SSF52096 892 1100 1.82E-62 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 Pfam PF07676 WD40-like Beta Propeller Repeat 485 517 0.0017 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 Pfam PF07676 WD40-like Beta Propeller Repeat 58 75 0.01 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 Gene3D G3DSA:2.30.42.10 778 896 2.6E-27 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 Pfam PF14685 Tricorn protease PDZ domain 779 855 3.9E-23 T 23-04-2016 IPR029414 Tricorn protease, PDZ domain DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 Pfam PF14684 Tricorn protease C1 domain 696 764 9.9E-28 T 23-04-2016 IPR028204 Tricorn protease C1 domain DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 Gene3D G3DSA:2.120.10.60 9 260 1.5E-52 T 23-04-2016 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 Gene3D G3DSA:3.90.226.10 899 1105 6.5E-37 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 Pfam PF03572 Peptidase family S41 920 1073 4.1E-23 T 23-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 PANTHER PTHR32060:SF12 886 1126 0.0 T 23-04-2016 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 PANTHER PTHR32060 435 866 0.0 T 23-04-2016 DC74_RS17695 9cd3c9d02f40268c636ba9e5515ae835 1128 SUPERFAMILY SSF69322 302 560 2.22E-20 T 23-04-2016 DC74_RS23575 0ad160b73b5ed8ec2ef577492e6ec1dd 317 Gene3D G3DSA:3.40.50.10490 14 261 2.0E-82 T 23-04-2016 DC74_RS23575 0ad160b73b5ed8ec2ef577492e6ec1dd 317 PANTHER PTHR10088 3 307 1.6E-132 T 23-04-2016 DC74_RS23575 0ad160b73b5ed8ec2ef577492e6ec1dd 317 Pfam PF01380 SIS domain 138 219 2.7E-10 T 23-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 DC74_RS23575 0ad160b73b5ed8ec2ef577492e6ec1dd 317 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 14 307 41.848 T 23-04-2016 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|UniPathway: UPA00342 DC74_RS23575 0ad160b73b5ed8ec2ef577492e6ec1dd 317 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 18 307 4.6E-112 T 23-04-2016 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|UniPathway: UPA00342 DC74_RS23575 0ad160b73b5ed8ec2ef577492e6ec1dd 317 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 197 214 - T 23-04-2016 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|UniPathway: UPA00342 DC74_RS23575 0ad160b73b5ed8ec2ef577492e6ec1dd 317 SUPERFAMILY SSF53697 18 259 2.43E-66 T 23-04-2016 DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 Gene3D G3DSA:3.30.565.10 265 397 1.1E-17 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 Pfam PF00672 HAMP domain 129 196 1.0E-12 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 SUPERFAMILY SSF158472 150 197 4.18E-9 T 23-04-2016 DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 SUPERFAMILY SSF55874 265 401 1.57E-19 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 Gene3D G3DSA:1.10.287.130 191 255 7.9E-10 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 298 397 8.6E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 Pfam PF00512 His Kinase A (phospho-acceptor) domain 202 257 5.8E-7 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 SMART SM00388 201 259 1.0E-8 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 SUPERFAMILY SSF47384 185 258 1.75E-10 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 SMART SM00387 298 401 3.0E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 PANTHER PTHR24423 142 397 8.8E-32 T 23-04-2016 DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 PANTHER PTHR24423 64 82 8.8E-32 T 23-04-2016 DC74_RS35785 a48c0c9fd0c8ac278ff6a5374ce738e4 421 SMART SM00304 148 200 8.3E-11 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS25450 14d776a60ba122c3e372484bd99fa73b 200 PRINTS PR01021 OMPA domain signature 125 140 2.1E-6 T 23-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 DC74_RS25450 14d776a60ba122c3e372484bd99fa73b 200 PRINTS PR01021 OMPA domain signature 95 117 2.1E-6 T 23-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 DC74_RS25450 14d776a60ba122c3e372484bd99fa73b 200 PRINTS PR01021 OMPA domain signature 140 156 2.1E-6 T 23-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 DC74_RS25450 14d776a60ba122c3e372484bd99fa73b 200 SUPERFAMILY SSF103088 82 195 1.1E-28 T 23-04-2016 IPR006665 OmpA-like domain DC74_RS25450 14d776a60ba122c3e372484bd99fa73b 200 Pfam PF00691 OmpA family 94 189 1.0E-12 T 23-04-2016 IPR006665 OmpA-like domain DC74_RS25450 14d776a60ba122c3e372484bd99fa73b 200 PANTHER PTHR30128 41 193 8.3E-30 T 23-04-2016 DC74_RS25450 14d776a60ba122c3e372484bd99fa73b 200 Gene3D G3DSA:3.30.1330.60 78 195 5.8E-29 T 23-04-2016 IPR006665 OmpA-like domain DC74_RS27100 e82dfee34b5e46100750a567a84df581 220 Pfam PF01939 Protein of unknown function DUF91 2 220 1.6E-82 T 23-04-2016 IPR002793 Endonuclease NucS DC74_RS27100 e82dfee34b5e46100750a567a84df581 220 Hamap MF_00722 Endonuclease NucS [nucS]. 1 212 31.584 T 23-04-2016 IPR002793 Endonuclease NucS DC74_RS27100 e82dfee34b5e46100750a567a84df581 220 PANTHER PTHR38814 1 220 4.5E-168 T 23-04-2016 DC74_RS27100 e82dfee34b5e46100750a567a84df581 220 PANTHER PTHR38814:SF2 1 220 4.5E-168 T 23-04-2016 DC74_RS37815 416f4a8d06fd2337373f70e7d8f564c5 265 SUPERFAMILY SSF55961 102 260 3.75E-29 T 23-04-2016 DC74_RS37815 416f4a8d06fd2337373f70e7d8f564c5 265 Gene3D G3DSA:1.10.10.10 1 100 6.9E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37815 416f4a8d06fd2337373f70e7d8f564c5 265 Pfam PF12840 Helix-turn-helix domain 2 62 2.5E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37815 416f4a8d06fd2337373f70e7d8f564c5 265 PANTHER PTHR38600 1 123 1.3E-19 T 23-04-2016 DC74_RS37815 416f4a8d06fd2337373f70e7d8f564c5 265 SUPERFAMILY SSF46785 1 100 9.92E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37815 416f4a8d06fd2337373f70e7d8f564c5 265 PANTHER PTHR38600:SF1 1 123 1.3E-19 T 23-04-2016 DC74_RS37815 416f4a8d06fd2337373f70e7d8f564c5 265 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 4.6E-5 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS37815 416f4a8d06fd2337373f70e7d8f564c5 265 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 4.6E-5 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS37815 416f4a8d06fd2337373f70e7d8f564c5 265 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 4.6E-5 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS37815 416f4a8d06fd2337373f70e7d8f564c5 265 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 117 254 3.1E-23 T 23-04-2016 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 DC74_RS37815 416f4a8d06fd2337373f70e7d8f564c5 265 SMART SM00418 3 78 3.1E-16 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS37815 416f4a8d06fd2337373f70e7d8f564c5 265 Gene3D G3DSA:3.30.530.20 104 261 7.4E-28 T 23-04-2016 IPR023393 START-like domain DC74_RS06645 1f00b3fc04fa13ed02cc33e7a50a9193 96 Gene3D G3DSA:3.40.50.1820 2 52 2.4E-13 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS06645 1f00b3fc04fa13ed02cc33e7a50a9193 96 SUPERFAMILY SSF53474 1 51 5.06E-13 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS06645 1f00b3fc04fa13ed02cc33e7a50a9193 96 Pfam PF00561 alpha/beta hydrolase fold 1 51 1.2E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS33195 bd91d49b0ef4ce07281f4ad0f41a9c78 296 Gene3D G3DSA:3.90.550.10 6 226 2.7E-23 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS33195 bd91d49b0ef4ce07281f4ad0f41a9c78 296 PANTHER PTHR22916 6 252 2.6E-31 T 23-04-2016 DC74_RS33195 bd91d49b0ef4ce07281f4ad0f41a9c78 296 SUPERFAMILY SSF53448 5 226 3.0E-33 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS33195 bd91d49b0ef4ce07281f4ad0f41a9c78 296 Pfam PF00535 Glycosyl transferase family 2 6 129 7.9E-10 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS37910 5b2dc0ebfeedd80bf1066f6bdea9bb16 349 SUPERFAMILY SSF48264 24 313 4.85E-21 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37910 5b2dc0ebfeedd80bf1066f6bdea9bb16 349 PANTHER PTHR24286:SF77 220 307 3.9E-15 T 23-04-2016 DC74_RS37910 5b2dc0ebfeedd80bf1066f6bdea9bb16 349 PANTHER PTHR24286 220 307 3.9E-15 T 23-04-2016 DC74_RS37910 5b2dc0ebfeedd80bf1066f6bdea9bb16 349 Gene3D G3DSA:1.10.630.10 220 305 2.8E-19 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37910 5b2dc0ebfeedd80bf1066f6bdea9bb16 349 Pfam PF00067 Cytochrome P450 220 305 2.2E-13 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS07635 2b3fc13eb208dc7f836b464a6f3633a8 389 PANTHER PTHR22935:SF69 61 368 1.4E-59 T 23-04-2016 DC74_RS07635 2b3fc13eb208dc7f836b464a6f3633a8 389 Pfam PF00144 Beta-lactamase 65 358 7.5E-55 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS07635 2b3fc13eb208dc7f836b464a6f3633a8 389 PANTHER PTHR22935 61 368 1.4E-59 T 23-04-2016 DC74_RS07635 2b3fc13eb208dc7f836b464a6f3633a8 389 SUPERFAMILY SSF56601 52 368 3.81E-74 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS07635 2b3fc13eb208dc7f836b464a6f3633a8 389 Gene3D G3DSA:3.40.710.10 64 352 2.6E-75 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS09900 b425a3bf4fd5d40d945c0a17f825fab3 416 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 30 406 41.51 T 23-04-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 DC74_RS09900 b425a3bf4fd5d40d945c0a17f825fab3 416 SUPERFAMILY SSF53383 32 406 1.25E-118 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS09900 b425a3bf4fd5d40d945c0a17f825fab3 416 PANTHER PTHR11986:SF79 23 413 2.5E-154 T 23-04-2016 DC74_RS09900 b425a3bf4fd5d40d945c0a17f825fab3 416 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 33 405 2.6E-132 T 23-04-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 DC74_RS09900 b425a3bf4fd5d40d945c0a17f825fab3 416 Pfam PF00202 Aminotransferase class-III 42 402 8.7E-102 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS09900 b425a3bf4fd5d40d945c0a17f825fab3 416 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 233 270 - T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS09900 b425a3bf4fd5d40d945c0a17f825fab3 416 Gene3D G3DSA:3.40.640.10 77 314 1.0E-81 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS09900 b425a3bf4fd5d40d945c0a17f825fab3 416 Gene3D G3DSA:3.90.1150.10 23 76 3.4E-38 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS09900 b425a3bf4fd5d40d945c0a17f825fab3 416 Gene3D G3DSA:3.90.1150.10 317 406 3.4E-38 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS09900 b425a3bf4fd5d40d945c0a17f825fab3 416 PANTHER PTHR11986 23 413 2.5E-154 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS12345 543d138539232290e1ca8f61b0146ff7 208 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 1 207 9.3E-77 T 23-04-2016 IPR011138 Succinate dehydrogenase cytochrome b558 subunit UniPathway: UPA00223 DC74_RS12345 543d138539232290e1ca8f61b0146ff7 208 SUPERFAMILY SSF81343 1 207 3.11E-50 T 23-04-2016 DC74_RS12345 543d138539232290e1ca8f61b0146ff7 208 Gene3D G3DSA:1.20.950.10 3 198 4.3E-13 T 23-04-2016 DC74_RS11945 54630f07d3d9c02965a1210c6d07128e 199 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 34 106 4.5E-8 T 23-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 DC74_RS11945 54630f07d3d9c02965a1210c6d07128e 199 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 113 193 4.2E-28 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS11945 54630f07d3d9c02965a1210c6d07128e 199 SUPERFAMILY SSF53155 29 107 6.87E-12 T 23-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 DC74_RS11945 54630f07d3d9c02965a1210c6d07128e 199 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 28 194 35.145 T 23-04-2016 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 DC74_RS11945 54630f07d3d9c02965a1210c6d07128e 199 Gene3D G3DSA:1.10.10.10 113 193 8.0E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11945 54630f07d3d9c02965a1210c6d07128e 199 Gene3D G3DSA:3.30.160.70 35 106 6.7E-4 T 23-04-2016 DC74_RS11945 54630f07d3d9c02965a1210c6d07128e 199 PANTHER PTHR10815 30 193 1.1E-45 T 23-04-2016 DC74_RS11945 54630f07d3d9c02965a1210c6d07128e 199 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 113 191 8.1E-29 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS11945 54630f07d3d9c02965a1210c6d07128e 199 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 162 168 - T 23-04-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 DC74_RS11945 54630f07d3d9c02965a1210c6d07128e 199 SUPERFAMILY SSF46767 113 193 1.03E-25 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS11945 54630f07d3d9c02965a1210c6d07128e 199 PANTHER PTHR10815:SF5 30 193 1.1E-45 T 23-04-2016 DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 PANTHER PTHR30204:SF5 1 208 4.3E-44 T 23-04-2016 DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 SMART SM00422 3 72 6.6E-31 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 Gene3D G3DSA:1.10.1660.10 3 56 1.1E-24 T 23-04-2016 DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 Pfam PF13411 MerR HTH family regulatory protein 3 70 7.7E-16 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 Gene3D G3DSA:1.10.1660.10 57 105 6.5E-8 T 23-04-2016 DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.6E-8 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.6E-8 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.6E-8 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 Gene3D G3DSA:1.10.490.50 161 255 3.8E-19 T 23-04-2016 IPR012925 TipAS antibiotic-recognition domain DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 PANTHER PTHR30204 1 208 4.3E-44 T 23-04-2016 DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 Pfam PF07739 TipAS antibiotic-recognition domain 132 251 2.7E-22 T 23-04-2016 IPR012925 TipAS antibiotic-recognition domain DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 SUPERFAMILY SSF89082 161 252 1.22E-12 T 23-04-2016 IPR012925 TipAS antibiotic-recognition domain DC74_RS17795 7b51df3ec6c130bc39abd4502cf1a0a7 271 SUPERFAMILY SSF46955 3 103 5.86E-28 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS39430 24b2e03ea3b9b4fed51ad6745e6e3b36 420 Gene3D G3DSA:1.20.1250.20 9 190 2.0E-8 T 23-04-2016 DC74_RS39430 24b2e03ea3b9b4fed51ad6745e6e3b36 420 Gene3D G3DSA:1.20.1250.20 219 395 8.0E-14 T 23-04-2016 DC74_RS39430 24b2e03ea3b9b4fed51ad6745e6e3b36 420 PANTHER PTHR23513 6 399 5.2E-32 T 23-04-2016 DC74_RS39430 24b2e03ea3b9b4fed51ad6745e6e3b36 420 Pfam PF07690 Major Facilitator Superfamily 15 331 4.0E-20 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS39430 24b2e03ea3b9b4fed51ad6745e6e3b36 420 SUPERFAMILY SSF103473 9 396 8.24E-35 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS34810 26c713caa71a8117030e64041817636b 146 PANTHER PTHR30154 2 142 3.6E-48 T 23-04-2016 DC74_RS34810 26c713caa71a8117030e64041817636b 146 SMART SM00344 3 108 2.8E-43 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS34810 26c713caa71a8117030e64041817636b 146 Pfam PF13404 AsnC-type helix-turn-helix domain 3 42 4.7E-16 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS34810 26c713caa71a8117030e64041817636b 146 PANTHER PTHR30154:SF2 2 142 3.6E-48 T 23-04-2016 DC74_RS34810 26c713caa71a8117030e64041817636b 146 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 23-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site DC74_RS34810 26c713caa71a8117030e64041817636b 146 SUPERFAMILY SSF46785 2 60 2.0E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34810 26c713caa71a8117030e64041817636b 146 Gene3D G3DSA:3.30.70.920 54 133 1.3E-23 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS34810 26c713caa71a8117030e64041817636b 146 Pfam PF01037 Lrp/AsnC ligand binding domain 67 137 1.6E-14 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS34810 26c713caa71a8117030e64041817636b 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 8.7E-16 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS34810 26c713caa71a8117030e64041817636b 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 8.7E-16 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS34810 26c713caa71a8117030e64041817636b 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 8.7E-16 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS34810 26c713caa71a8117030e64041817636b 146 Gene3D G3DSA:1.10.10.10 3 53 1.3E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34810 26c713caa71a8117030e64041817636b 146 SUPERFAMILY SSF54909 61 144 1.79E-14 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS18445 76557e738f88d8f243908fbebbb2fb8b 191 SUPERFAMILY SSF88659 116 189 1.87E-14 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS18445 76557e738f88d8f243908fbebbb2fb8b 191 Pfam PF08281 Sigma-70, region 4 136 185 5.9E-12 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS18445 76557e738f88d8f243908fbebbb2fb8b 191 Pfam PF04542 Sigma-70 region 2 27 98 1.4E-9 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS18445 76557e738f88d8f243908fbebbb2fb8b 191 Gene3D G3DSA:1.10.1740.10 10 125 9.2E-16 T 23-04-2016 DC74_RS18445 76557e738f88d8f243908fbebbb2fb8b 191 SUPERFAMILY SSF88946 8 115 7.85E-16 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS18445 76557e738f88d8f243908fbebbb2fb8b 191 PANTHER PTHR30173 1 191 8.4E-76 T 23-04-2016 DC74_RS18445 76557e738f88d8f243908fbebbb2fb8b 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 186 1.7E-22 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS18445 76557e738f88d8f243908fbebbb2fb8b 191 PANTHER PTHR30173:SF3 1 191 8.4E-76 T 23-04-2016 DC74_RS18445 76557e738f88d8f243908fbebbb2fb8b 191 Gene3D G3DSA:1.10.10.10 132 189 4.7E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06730 39de5366c2c711390c44ba759292dc7b 489 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 32 434 1.1E-76 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS06730 39de5366c2c711390c44ba759292dc7b 489 SUPERFAMILY SSF103473 21 217 9.16E-69 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS06730 39de5366c2c711390c44ba759292dc7b 489 SUPERFAMILY SSF103473 265 478 9.16E-69 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS06730 39de5366c2c711390c44ba759292dc7b 489 PANTHER PTHR23501:SF91 27 468 3.3E-142 T 23-04-2016 DC74_RS06730 39de5366c2c711390c44ba759292dc7b 489 Pfam PF07690 Major Facilitator Superfamily 37 426 4.8E-57 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS06730 39de5366c2c711390c44ba759292dc7b 489 PANTHER PTHR23501 27 468 3.3E-142 T 23-04-2016 DC74_RS06730 39de5366c2c711390c44ba759292dc7b 489 Gene3D G3DSA:1.20.1250.20 28 217 1.1E-34 T 23-04-2016 DC74_RS06730 39de5366c2c711390c44ba759292dc7b 489 Gene3D G3DSA:1.20.1250.20 275 480 2.2E-24 T 23-04-2016 DC74_RS03620 af68713787b1da82c1529fc31d588fa1 494 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 85 95 - T 23-04-2016 IPR019819 Carboxylesterase type B, conserved site DC74_RS03620 af68713787b1da82c1529fc31d588fa1 494 PANTHER PTHR11559:SF142 2 467 1.3E-116 T 23-04-2016 DC74_RS03620 af68713787b1da82c1529fc31d588fa1 494 PRINTS PR00878 Cholinesterase signature 112 141 1.4E-5 T 23-04-2016 IPR000997 Cholinesterase GO:0004104 DC74_RS03620 af68713787b1da82c1529fc31d588fa1 494 PRINTS PR00878 Cholinesterase signature 420 432 1.4E-5 T 23-04-2016 IPR000997 Cholinesterase GO:0004104 DC74_RS03620 af68713787b1da82c1529fc31d588fa1 494 Gene3D G3DSA:3.40.50.1820 3 470 2.6E-119 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS03620 af68713787b1da82c1529fc31d588fa1 494 Pfam PF00135 Carboxylesterase family 6 469 6.2E-91 T 23-04-2016 IPR002018 Carboxylesterase, type B DC74_RS03620 af68713787b1da82c1529fc31d588fa1 494 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 181 196 - T 23-04-2016 IPR019826 Carboxylesterase type B, active site DC74_RS03620 af68713787b1da82c1529fc31d588fa1 494 PANTHER PTHR11559 2 467 1.3E-116 T 23-04-2016 DC74_RS03620 af68713787b1da82c1529fc31d588fa1 494 SUPERFAMILY SSF53474 6 469 3.91E-102 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08415 c4fc35157b2c67f154c1bd484af9b2f7 266 PANTHER PTHR33993 1 265 1.6E-88 T 23-04-2016 DC74_RS08415 c4fc35157b2c67f154c1bd484af9b2f7 266 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 118 9.5E-7 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS08415 c4fc35157b2c67f154c1bd484af9b2f7 266 SUPERFAMILY SSF54593 10 126 5.1E-20 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS08415 c4fc35157b2c67f154c1bd484af9b2f7 266 SUPERFAMILY SSF54593 133 261 3.22E-18 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS08415 c4fc35157b2c67f154c1bd484af9b2f7 266 PANTHER PTHR33993:SF3 1 265 1.6E-88 T 23-04-2016 DC74_RS08415 c4fc35157b2c67f154c1bd484af9b2f7 266 Gene3D G3DSA:3.10.180.10 137 260 6.1E-32 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS08415 c4fc35157b2c67f154c1bd484af9b2f7 266 Gene3D G3DSA:3.10.180.10 11 125 2.5E-32 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS16840 915f0f6a9ffcc7664fa9ee3a1528a030 207 SUPERFAMILY SSF55729 1 178 9.55E-45 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS16840 915f0f6a9ffcc7664fa9ee3a1528a030 207 Gene3D G3DSA:3.40.630.30 1 183 4.0E-54 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS16840 915f0f6a9ffcc7664fa9ee3a1528a030 207 PANTHER PTHR13256 3 201 4.7E-52 T 23-04-2016 DC74_RS16840 915f0f6a9ffcc7664fa9ee3a1528a030 207 PANTHER PTHR13256:SF21 3 201 4.7E-52 T 23-04-2016 DC74_RS16840 915f0f6a9ffcc7664fa9ee3a1528a030 207 Pfam PF13302 Acetyltransferase (GNAT) domain 10 154 2.7E-30 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS21360 585f2abc2d4940d878ea918a8d4b84e6 355 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 107 1.1E-5 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS21360 585f2abc2d4940d878ea918a8d4b84e6 355 Gene3D G3DSA:1.10.540.10 2 107 1.1E-6 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS21360 585f2abc2d4940d878ea918a8d4b84e6 355 SUPERFAMILY SSF56645 2 179 2.26E-12 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS21360 585f2abc2d4940d878ea918a8d4b84e6 355 Gene3D G3DSA:1.20.140.10 205 352 1.8E-28 T 23-04-2016 DC74_RS21360 585f2abc2d4940d878ea918a8d4b84e6 355 SUPERFAMILY SSF47203 209 350 2.26E-28 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS21360 585f2abc2d4940d878ea918a8d4b84e6 355 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 210 339 3.9E-20 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS21360 585f2abc2d4940d878ea918a8d4b84e6 355 PANTHER PTHR10909 1 326 2.3E-38 T 23-04-2016 DC74_RS21360 585f2abc2d4940d878ea918a8d4b84e6 355 PANTHER PTHR10909:SF302 1 326 2.3E-38 T 23-04-2016 DC74_RS38740 87dcbe8b26f80f6de5b9f8a6b2d34296 463 PANTHER PTHR11926:SF16 3 435 2.8E-46 T 23-04-2016 DC74_RS38740 87dcbe8b26f80f6de5b9f8a6b2d34296 463 Gene3D G3DSA:3.40.50.2000 284 438 1.5E-18 T 23-04-2016 DC74_RS38740 87dcbe8b26f80f6de5b9f8a6b2d34296 463 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 104 434 2.7E-29 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS38740 87dcbe8b26f80f6de5b9f8a6b2d34296 463 SUPERFAMILY SSF53756 8 453 1.02E-66 T 23-04-2016 DC74_RS38740 87dcbe8b26f80f6de5b9f8a6b2d34296 463 PANTHER PTHR11926 3 435 2.8E-46 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS38740 87dcbe8b26f80f6de5b9f8a6b2d34296 463 Gene3D G3DSA:3.40.50.2000 197 283 1.0E-11 T 23-04-2016 DC74_RS38740 87dcbe8b26f80f6de5b9f8a6b2d34296 463 Gene3D G3DSA:3.40.50.2000 8 163 1.0E-11 T 23-04-2016 DC74_RS20035 3da43e88ae73e1ca4c9a352fefd0955a 297 PIRSF PIRSF015582 1 296 1.2E-83 T 23-04-2016 IPR011206 Citrate lyase beta subunit-like DC74_RS20035 3da43e88ae73e1ca4c9a352fefd0955a 297 Gene3D G3DSA:3.20.20.60 11 240 3.1E-77 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS20035 3da43e88ae73e1ca4c9a352fefd0955a 297 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 15 229 2.0E-47 T 23-04-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 DC74_RS20035 3da43e88ae73e1ca4c9a352fefd0955a 297 SUPERFAMILY SSF51621 12 239 1.4E-68 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS20035 3da43e88ae73e1ca4c9a352fefd0955a 297 PANTHER PTHR32308:SF0 12 293 8.3E-87 T 23-04-2016 DC74_RS20035 3da43e88ae73e1ca4c9a352fefd0955a 297 PANTHER PTHR32308 12 293 8.3E-87 T 23-04-2016 IPR011206 Citrate lyase beta subunit-like DC74_RS05070 b1eff67339577d38df609ff6c3e0c579 274 Pfam PF00005 ABC transporter 25 167 2.4E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS05070 b1eff67339577d38df609ff6c3e0c579 274 SUPERFAMILY SSF52540 3 224 2.51E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05070 b1eff67339577d38df609ff6c3e0c579 274 SMART SM00382 27 211 7.1E-19 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS05070 b1eff67339577d38df609ff6c3e0c579 274 PANTHER PTHR24220:SF309 4 247 9.7E-92 T 23-04-2016 DC74_RS05070 b1eff67339577d38df609ff6c3e0c579 274 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS05070 b1eff67339577d38df609ff6c3e0c579 274 PANTHER PTHR24220 4 247 9.7E-92 T 23-04-2016 DC74_RS05070 b1eff67339577d38df609ff6c3e0c579 274 Gene3D G3DSA:3.40.50.300 3 225 9.5E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21120 3c3b950d0e730b7b1784a440ec7834ea 236 SUPERFAMILY SSF48008 91 229 8.11E-27 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS21120 3c3b950d0e730b7b1784a440ec7834ea 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 4.9E-19 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS21120 3c3b950d0e730b7b1784a440ec7834ea 236 Pfam PF07729 FCD domain 94 223 1.6E-23 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS21120 3c3b950d0e730b7b1784a440ec7834ea 236 PANTHER PTHR11751 8 110 1.2E-31 T 23-04-2016 DC74_RS21120 3c3b950d0e730b7b1784a440ec7834ea 236 SMART SM00895 94 224 1.7E-23 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS21120 3c3b950d0e730b7b1784a440ec7834ea 236 Gene3D G3DSA:1.20.120.530 89 233 4.7E-29 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS21120 3c3b950d0e730b7b1784a440ec7834ea 236 SUPERFAMILY SSF46785 5 108 8.88E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21120 3c3b950d0e730b7b1784a440ec7834ea 236 PANTHER PTHR11751:SF342 8 110 1.2E-31 T 23-04-2016 DC74_RS21120 3c3b950d0e730b7b1784a440ec7834ea 236 SMART SM00345 15 74 4.2E-19 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS21120 3c3b950d0e730b7b1784a440ec7834ea 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.6E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS21120 3c3b950d0e730b7b1784a440ec7834ea 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.6E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS21120 3c3b950d0e730b7b1784a440ec7834ea 236 Gene3D G3DSA:1.10.10.10 5 77 7.7E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06575 21ac261ff8db160e55d4d55dee962bc7 231 Gene3D G3DSA:3.40.50.300 24 216 1.7E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06575 21ac261ff8db160e55d4d55dee962bc7 231 SUPERFAMILY SSF52540 23 204 2.81E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14905 f168d9872369bc4adb84467281ef9e53 210 PANTHER PTHR11711 23 205 2.4E-46 T 23-04-2016 DC74_RS14905 f168d9872369bc4adb84467281ef9e53 210 PANTHER PTHR11711:SF117 23 205 2.4E-46 T 23-04-2016 DC74_RS14905 f168d9872369bc4adb84467281ef9e53 210 Pfam PF03029 Conserved hypothetical ATP binding protein 31 136 5.6E-17 T 23-04-2016 IPR004130 GPN-loop GTPase DC74_RS14905 f168d9872369bc4adb84467281ef9e53 210 Gene3D G3DSA:3.40.50.300 150 179 6.3E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14905 f168d9872369bc4adb84467281ef9e53 210 Gene3D G3DSA:3.40.50.300 20 129 2.0E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14905 f168d9872369bc4adb84467281ef9e53 210 SUPERFAMILY SSF52540 23 208 3.14E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02795 ceda7fd2bac6fea96725a343304201ce 161 Gene3D G3DSA:2.40.380.10 4 156 1.8E-39 T 23-04-2016 IPR007295 Domain of unknown function DUF402 DC74_RS02795 ceda7fd2bac6fea96725a343304201ce 161 PANTHER PTHR39159 15 151 1.8E-43 T 23-04-2016 DC74_RS02795 ceda7fd2bac6fea96725a343304201ce 161 Pfam PF04167 Protein of unknown function (DUF402) 59 126 6.0E-20 T 23-04-2016 IPR007295 Domain of unknown function DUF402 DC74_RS02795 ceda7fd2bac6fea96725a343304201ce 161 SUPERFAMILY SSF159234 40 133 1.15E-14 T 23-04-2016 DC74_RS02795 ceda7fd2bac6fea96725a343304201ce 161 PANTHER PTHR39159:SF1 15 151 1.8E-43 T 23-04-2016 DC74_RS27195 c5d611a7cfb476bd7af834a7f1f8d284 329 Gene3D G3DSA:1.10.10.10 264 320 9.4E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27195 c5d611a7cfb476bd7af834a7f1f8d284 329 SMART SM00418 256 326 1.1E-4 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS27195 c5d611a7cfb476bd7af834a7f1f8d284 329 Pfam PF12840 Helix-turn-helix domain 264 311 3.2E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27195 c5d611a7cfb476bd7af834a7f1f8d284 329 SUPERFAMILY SSF46785 263 326 2.59E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27195 c5d611a7cfb476bd7af834a7f1f8d284 329 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 257 272 4.9E-5 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS27195 c5d611a7cfb476bd7af834a7f1f8d284 329 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 288 303 4.9E-5 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS27195 c5d611a7cfb476bd7af834a7f1f8d284 329 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 303 318 4.9E-5 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 Gene3D G3DSA:3.20.20.140 483 559 1.4E-142 T 23-04-2016 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 Gene3D G3DSA:3.20.20.140 141 424 1.4E-142 T 23-04-2016 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 Pfam PF00449 Urease alpha-subunit, N-terminal domain 2 117 1.0E-36 T 23-04-2016 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 Gene3D G3DSA:2.30.40.10 1 140 7.5E-43 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 Pfam PF01979 Amidohydrolase family 123 445 2.8E-43 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 SUPERFAMILY SSF51556 476 560 1.42E-140 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 SUPERFAMILY SSF51556 127 427 1.42E-140 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 SUPERFAMILY SSF51338 3 127 6.84E-40 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 SUPERFAMILY SSF51338 417 463 6.84E-40 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 PANTHER PTHR22642:SF7 315 496 3.7E-202 T 23-04-2016 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 PANTHER PTHR22642:SF7 25 291 3.7E-202 T 23-04-2016 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 Hamap MF_01953 Urease subunit alpha [ureC]. 1 560 45.31 T 23-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 396 411 6.3E-24 T 23-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 329 345 6.3E-24 T 23-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 290 307 6.3E-24 T 23-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 422 435 6.3E-24 T 23-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 ProSitePatterns PS01120 Urease nickel ligands signature. 125 138 - T 23-04-2016 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 PANTHER PTHR22642 315 496 3.7E-202 T 23-04-2016 DC74_RS27760 8ec7e89833aac76f0fe73a03d4a6b850 560 PANTHER PTHR22642 25 291 3.7E-202 T 23-04-2016 DC74_RS27190 e84530764b589a97c8ec5959a3641796 102 Gene3D G3DSA:3.30.70.930 1 92 1.9E-34 T 23-04-2016 IPR029756 MTH1187/YkoF-like DC74_RS27190 e84530764b589a97c8ec5959a3641796 102 SUPERFAMILY SSF89957 1 95 5.76E-29 T 23-04-2016 IPR029756 MTH1187/YkoF-like DC74_RS27190 e84530764b589a97c8ec5959a3641796 102 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 1 94 1.7E-17 T 23-04-2016 IPR002767 Thiamine-binding protein DC74_RS27190 e84530764b589a97c8ec5959a3641796 102 PANTHER PTHR33777 1 101 5.7E-32 T 23-04-2016 DC74_RS27190 e84530764b589a97c8ec5959a3641796 102 Pfam PF01910 Thiamine-binding protein 3 92 2.9E-29 T 23-04-2016 IPR002767 Thiamine-binding protein DC74_RS28320 418f68adba052faaa7d79a4468c2bcac 392 Pfam PF08402 TOBE domain 288 367 1.4E-13 T 23-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 DC74_RS28320 418f68adba052faaa7d79a4468c2bcac 392 Pfam PF00005 ABC transporter 29 168 9.9E-34 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS28320 418f68adba052faaa7d79a4468c2bcac 392 SUPERFAMILY SSF52540 13 251 2.85E-86 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28320 418f68adba052faaa7d79a4468c2bcac 392 PANTHER PTHR24220:SF150 14 253 4.0E-136 T 23-04-2016 DC74_RS28320 418f68adba052faaa7d79a4468c2bcac 392 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 43 365 2.3E-108 T 23-04-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 DC74_RS28320 418f68adba052faaa7d79a4468c2bcac 392 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS28320 418f68adba052faaa7d79a4468c2bcac 392 PANTHER PTHR24220 14 253 4.0E-136 T 23-04-2016 DC74_RS28320 418f68adba052faaa7d79a4468c2bcac 392 Gene3D G3DSA:3.40.50.300 5 242 4.2E-77 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28320 418f68adba052faaa7d79a4468c2bcac 392 SUPERFAMILY SSF50331 244 367 7.14E-16 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal DC74_RS28320 418f68adba052faaa7d79a4468c2bcac 392 SMART SM00382 37 218 5.9E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS25745 a454b81ceddd786d95cb397996964c7a 249 Gene3D G3DSA:3.40.1410.10 73 244 3.9E-51 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS25745 a454b81ceddd786d95cb397996964c7a 249 SUPERFAMILY SSF64288 59 247 6.12E-23 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS25745 a454b81ceddd786d95cb397996964c7a 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.9E-15 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS25745 a454b81ceddd786d95cb397996964c7a 249 SMART SM00345 12 71 1.3E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS25745 a454b81ceddd786d95cb397996964c7a 249 SUPERFAMILY SSF46785 4 82 2.59E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25745 a454b81ceddd786d95cb397996964c7a 249 Pfam PF07702 UTRA domain 110 240 2.1E-13 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS25745 a454b81ceddd786d95cb397996964c7a 249 Gene3D G3DSA:1.10.10.10 8 72 5.2E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25745 a454b81ceddd786d95cb397996964c7a 249 SMART SM00866 97 241 1.5E-12 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS16420 8b8d23f7398d54b1cc94c9ea6ce774b9 796 PANTHER PTHR22935:SF71 164 503 1.7E-160 T 23-04-2016 DC74_RS16420 8b8d23f7398d54b1cc94c9ea6ce774b9 796 Gene3D G3DSA:3.40.390.10 339 418 2.5E-27 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 DC74_RS16420 8b8d23f7398d54b1cc94c9ea6ce774b9 796 Gene3D G3DSA:3.40.390.10 228 276 2.5E-27 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 DC74_RS16420 8b8d23f7398d54b1cc94c9ea6ce774b9 796 Pfam PF05547 Immune inhibitor A peptidase M6 97 788 2.5E-222 T 23-04-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 DC74_RS16420 8b8d23f7398d54b1cc94c9ea6ce774b9 796 PIRSF PIRSF007519 1 794 4.8E-218 T 23-04-2016 IPR012300 Peptidase M6, InhA DC74_RS16420 8b8d23f7398d54b1cc94c9ea6ce774b9 796 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 163 470 3.3E-83 T 23-04-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 DC74_RS16420 8b8d23f7398d54b1cc94c9ea6ce774b9 796 SUPERFAMILY SSF55486 339 418 8.81E-17 T 23-04-2016 DC74_RS16420 8b8d23f7398d54b1cc94c9ea6ce774b9 796 SUPERFAMILY SSF55486 226 285 8.81E-17 T 23-04-2016 DC74_RS16420 8b8d23f7398d54b1cc94c9ea6ce774b9 796 PANTHER PTHR22935 164 503 1.7E-160 T 23-04-2016 DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 SUPERFAMILY SSF81271 278 362 6.98E-35 T 23-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 SUPERFAMILY SSF52540 3 300 5.33E-74 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 Pfam PF01926 50S ribosome-binding GTPase 5 128 7.8E-23 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 PANTHER PTHR23305 2 362 1.2E-176 T 23-04-2016 DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 Gene3D G3DSA:3.40.50.300 3 131 1.7E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 Gene3D G3DSA:3.40.50.300 202 261 1.7E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 PIRSF PIRSF006641 1 362 7.0E-142 T 23-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 362 7.0E-132 T 23-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 Gene3D G3DSA:3.10.20.30 262 362 6.2E-45 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 362 42.13 T 23-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 Gene3D G3DSA:1.10.150.300 132 201 1.8E-19 T 23-04-2016 IPR023192 TGS-like domain DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.2E-34 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 3.2E-34 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.2E-34 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 3.2E-34 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 Pfam PF06071 Protein of unknown function (DUF933) 278 361 6.1E-39 T 23-04-2016 IPR013029 Domain of unknown function DUF933 DC74_RS25660 19322c7f62adf62e44976765f8eaf1f4 362 PANTHER PTHR23305:SF12 2 362 1.2E-176 T 23-04-2016 DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 Gene3D G3DSA:3.30.1490.20 129 201 4.8E-21 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 320 2.8E-75 T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 Gene3D G3DSA:2.40.50.100 517 588 2.8E-21 T 23-04-2016 DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 Pfam PF02785 Biotin carboxylase C-terminal domain 333 447 1.5E-34 T 23-04-2016 IPR005482 Biotin carboxylase, C-terminal DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 544 561 - T 23-04-2016 IPR001882 Biotin-binding site DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 Pfam PF00364 Biotin-requiring enzyme 521 587 2.9E-16 T 23-04-2016 IPR000089 Biotin/lipoyl attachment DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 SUPERFAMILY SSF52440 2 112 1.29E-45 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 SMART SM00878 333 447 1.8E-49 T 23-04-2016 IPR005482 Biotin carboxylase, C-terminal DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 PANTHER PTHR18866:SF100 1 589 1.3E-300 T 23-04-2016 DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 SUPERFAMILY SSF56059 114 321 1.1E-58 T 23-04-2016 DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 Gene3D G3DSA:3.30.470.20 203 450 7.2E-89 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 PANTHER PTHR18866 1 589 1.3E-300 T 23-04-2016 DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 SUPERFAMILY SSF51246 328 447 7.32E-35 T 23-04-2016 IPR011054 Rudiment single hybrid motif DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 Gene3D G3DSA:3.40.50.20 2 128 1.2E-48 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 SUPERFAMILY SSF51230 516 587 6.67E-19 T 23-04-2016 IPR011053 Single hybrid motif DC74_RS25090 af205c3fbaedbec2cdb278ce51e7520a 589 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 2.3E-43 T 23-04-2016 IPR005481 Biotin carboxylase-like, N-terminal domain DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 SUPERFAMILY SSF56024 401 573 6.91E-56 T 23-04-2016 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 SUPERFAMILY SSF140356 81 185 3.14E-35 T 23-04-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 SUPERFAMILY SSF143724 187 383 3.53E-64 T 23-04-2016 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 PANTHER PTHR30218:SF0 7 761 0.0 T 23-04-2016 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 Gene3D G3DSA:3.30.870.10 400 575 1.2E-78 T 23-04-2016 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 SUPERFAMILY SSF56024 576 758 1.48E-66 T 23-04-2016 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 Pfam PF02503 Polyphosphate kinase middle domain 199 389 6.7E-66 T 23-04-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 Hamap MF_00347 Polyphosphate kinase [ppk]. 81 757 33.799 T 23-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 Pfam PF13090 Polyphosphate kinase C-terminal domain 405 753 4.2E-154 T 23-04-2016 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 83 754 2.3E-251 T 23-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 PIRSF PIRSF015589 68 764 3.8E-282 T 23-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 Pfam PF13089 Polyphosphate kinase N-terminal domain 84 190 3.7E-37 T 23-04-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 PANTHER PTHR30218 7 761 0.0 T 23-04-2016 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 Gene3D G3DSA:3.30.1840.10 186 371 1.1E-72 T 23-04-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 DC74_RS23245 3e9f5e8f9f88aee2e755ea0dbe93dcf6 765 Gene3D G3DSA:3.30.870.10 576 757 4.0E-71 T 23-04-2016 DC74_RS09285 1613e366a53c2b5388a72cbd1d33e583 310 PANTHER PTHR30011:SF5 6 245 3.1E-62 T 23-04-2016 DC74_RS09285 1613e366a53c2b5388a72cbd1d33e583 310 Gene3D G3DSA:3.20.20.30 1 298 1.9E-64 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS09285 1613e366a53c2b5388a72cbd1d33e583 310 Pfam PF00296 Luciferase-like monooxygenase 17 243 1.1E-51 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS09285 1613e366a53c2b5388a72cbd1d33e583 310 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 23 283 3.2E-71 T 23-04-2016 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted DC74_RS09285 1613e366a53c2b5388a72cbd1d33e583 310 PANTHER PTHR30011 6 245 3.1E-62 T 23-04-2016 DC74_RS09285 1613e366a53c2b5388a72cbd1d33e583 310 SUPERFAMILY SSF51679 7 289 1.11E-59 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS28385 db958dc3b735e1990218c9b3b3514993 433 Gene3D G3DSA:2.30.42.10 122 237 2.0E-21 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS28385 db958dc3b735e1990218c9b3b3514993 433 Pfam PF02163 Peptidase family M50 13 386 3.4E-47 T 23-04-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 DC74_RS28385 db958dc3b735e1990218c9b3b3514993 433 SMART SM00228 149 230 1.7E-4 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS28385 db958dc3b735e1990218c9b3b3514993 433 SUPERFAMILY SSF50156 128 236 9.22E-17 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS28385 db958dc3b735e1990218c9b3b3514993 433 PANTHER PTHR22939:SF78 322 415 4.6E-35 T 23-04-2016 DC74_RS28385 db958dc3b735e1990218c9b3b3514993 433 PANTHER PTHR22939:SF78 182 306 4.6E-35 T 23-04-2016 DC74_RS28385 db958dc3b735e1990218c9b3b3514993 433 PANTHER PTHR22939 322 415 4.6E-35 T 23-04-2016 DC74_RS28385 db958dc3b735e1990218c9b3b3514993 433 PANTHER PTHR22939 182 306 4.6E-35 T 23-04-2016 DC74_RS21870 669c9c51ab14c8b07351d7363ec24df2 400 Pfam PF13796 Putative sensor 17 162 1.5E-12 T 23-04-2016 IPR025828 Putative sensor domain DC74_RS21870 669c9c51ab14c8b07351d7363ec24df2 400 SMART SM00387 298 400 6.2E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21870 669c9c51ab14c8b07351d7363ec24df2 400 PANTHER PTHR24421 172 398 4.3E-76 T 23-04-2016 DC74_RS21870 669c9c51ab14c8b07351d7363ec24df2 400 SUPERFAMILY SSF55874 277 397 2.29E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21870 669c9c51ab14c8b07351d7363ec24df2 400 Pfam PF07730 Histidine kinase 195 260 1.8E-14 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS21870 669c9c51ab14c8b07351d7363ec24df2 400 Gene3D G3DSA:3.30.565.10 272 399 5.9E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21870 669c9c51ab14c8b07351d7363ec24df2 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 397 4.2E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21870 669c9c51ab14c8b07351d7363ec24df2 400 PANTHER PTHR24421:SF19 172 398 4.3E-76 T 23-04-2016 DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 SMART SM00304 156 213 4.7E-8 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 310 417 8.3E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 PANTHER PTHR24423:SF427 1 12 1.6E-34 T 23-04-2016 DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 Pfam PF00672 HAMP domain 137 210 6.6E-9 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 PANTHER PTHR24423 150 423 1.6E-34 T 23-04-2016 DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 PANTHER PTHR24423 1 12 1.6E-34 T 23-04-2016 DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 SUPERFAMILY SSF55874 261 417 9.04E-19 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 SMART SM00387 310 419 2.1E-19 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 SUPERFAMILY SSF47384 197 270 2.35E-12 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 Gene3D G3DSA:3.30.565.10 259 401 1.4E-19 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 Gene3D G3DSA:1.10.287.130 204 258 1.5E-12 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 PANTHER PTHR24423:SF427 150 423 1.6E-34 T 23-04-2016 DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 SMART SM00388 214 272 1.9E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS22650 3b5efc910e264e642ae2de0c9256f425 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 215 271 2.6E-10 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS35955 860a5fb47c90cc0c2c626f882994e370 519 Pfam PF13520 Amino acid permease 5 377 1.8E-35 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS35955 860a5fb47c90cc0c2c626f882994e370 519 PANTHER PTHR11785:SF322 442 506 9.0E-72 T 23-04-2016 DC74_RS35955 860a5fb47c90cc0c2c626f882994e370 519 PANTHER PTHR11785 1 381 9.0E-72 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS35955 860a5fb47c90cc0c2c626f882994e370 519 PANTHER PTHR11785:SF322 1 381 9.0E-72 T 23-04-2016 DC74_RS35955 860a5fb47c90cc0c2c626f882994e370 519 PANTHER PTHR11785 442 506 9.0E-72 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS31585 d1a70c8a0119344a7316fa4247cf696d 742 PANTHER PTHR33406:SF5 7 733 3.5E-94 T 23-04-2016 DC74_RS31585 d1a70c8a0119344a7316fa4247cf696d 742 PANTHER PTHR33406 7 733 3.5E-94 T 23-04-2016 DC74_RS31585 d1a70c8a0119344a7316fa4247cf696d 742 Gene3D G3DSA:1.20.1640.10 512 707 3.7E-9 T 23-04-2016 DC74_RS31585 d1a70c8a0119344a7316fa4247cf696d 742 Gene3D G3DSA:1.20.1640.10 154 353 1.8E-27 T 23-04-2016 DC74_RS31585 d1a70c8a0119344a7316fa4247cf696d 742 SUPERFAMILY SSF82866 536 703 3.27E-9 T 23-04-2016 DC74_RS31585 d1a70c8a0119344a7316fa4247cf696d 742 Pfam PF03176 MMPL family 60 366 9.4E-44 T 23-04-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 DC74_RS31585 d1a70c8a0119344a7316fa4247cf696d 742 Pfam PF03176 MMPL family 462 712 2.8E-13 T 23-04-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 DC74_RS31585 d1a70c8a0119344a7316fa4247cf696d 742 SUPERFAMILY SSF82866 145 349 6.28E-28 T 23-04-2016 DC74_RS34925 134924a185ac00f20eb922fc9d4399d3 423 Gene3D G3DSA:3.20.20.80 13 321 2.2E-22 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS34925 134924a185ac00f20eb922fc9d4399d3 423 SUPERFAMILY SSF51445 13 343 5.95E-35 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 PANTHER PTHR32305 238 792 1.8E-124 T 23-04-2016 DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 PANTHER PTHR32305 865 1143 1.8E-124 T 23-04-2016 DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 PANTHER PTHR32305:SF6 238 792 1.8E-124 T 23-04-2016 DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 PANTHER PTHR32305:SF6 865 1143 1.8E-124 T 23-04-2016 DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 Pfam PF05593 RHS Repeat 940 969 1.8E-8 T 23-04-2016 IPR031325 RHS repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 Pfam PF05593 RHS Repeat 414 449 5.5E-9 T 23-04-2016 IPR031325 RHS repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 Pfam PF05593 RHS Repeat 323 351 1.3E-4 T 23-04-2016 IPR031325 RHS repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 Pfam PF05593 RHS Repeat 540 574 8.6E-5 T 23-04-2016 IPR031325 RHS repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 Pfam PF05593 RHS Repeat 455 492 3.8E-8 T 23-04-2016 IPR031325 RHS repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 Pfam PF05593 RHS Repeat 519 555 4.8E-7 T 23-04-2016 IPR031325 RHS repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 Pfam PF05593 RHS Repeat 624 660 2.4E-12 T 23-04-2016 IPR031325 RHS repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 Pfam PF05593 RHS Repeat 746 776 2.8E-7 T 23-04-2016 IPR031325 RHS repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 Pfam PF05593 RHS Repeat 497 533 1.6E-6 T 23-04-2016 IPR031325 RHS repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1069 1143 2.7E-22 T 23-04-2016 IPR022385 Rhs repeat-associated core GO:0097264 DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 Pfam PF03527 RHS protein 1044 1074 1.1E-9 T 23-04-2016 IPR001826 RHS protein DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 455 496 3.5E-9 T 23-04-2016 IPR006530 YD repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 304 339 3.2E-6 T 23-04-2016 IPR006530 YD repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 413 452 2.2E-6 T 23-04-2016 IPR006530 YD repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 746 776 8.0E-6 T 23-04-2016 IPR006530 YD repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 497 537 2.0E-6 T 23-04-2016 IPR006530 YD repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 788 825 6.5E-4 T 23-04-2016 IPR006530 YD repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 581 618 4.4E-4 T 23-04-2016 IPR006530 YD repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 540 580 1.6E-7 T 23-04-2016 IPR006530 YD repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 940 973 7.0E-8 T 23-04-2016 IPR006530 YD repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 665 699 4.4E-5 T 23-04-2016 IPR006530 YD repeat DC74_RS00140 b52e05cbc6ff9b5c93d53320ebd20c78 1281 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 623 663 7.2E-9 T 23-04-2016 IPR006530 YD repeat DC74_RS40515 fb31e8639e34e9ef24a6be7697cfa347 524 PANTHER PTHR11712:SF285 6 437 3.1E-118 T 23-04-2016 DC74_RS40515 fb31e8639e34e9ef24a6be7697cfa347 524 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 276 389 5.9E-29 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS40515 fb31e8639e34e9ef24a6be7697cfa347 524 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 41 268 4.2E-64 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS40515 fb31e8639e34e9ef24a6be7697cfa347 524 PANTHER PTHR11712 6 437 3.1E-118 T 23-04-2016 DC74_RS40515 fb31e8639e34e9ef24a6be7697cfa347 524 SUPERFAMILY SSF53901 38 384 1.67E-72 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40515 fb31e8639e34e9ef24a6be7697cfa347 524 SMART SM00825 Beta-ketoacyl synthase 42 442 3.6E-108 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS40515 fb31e8639e34e9ef24a6be7697cfa347 524 Gene3D G3DSA:3.40.47.10 39 280 1.1E-71 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40515 fb31e8639e34e9ef24a6be7697cfa347 524 Gene3D G3DSA:3.40.47.10 281 441 2.1E-36 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40515 fb31e8639e34e9ef24a6be7697cfa347 524 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 181 197 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS18715 d5f03820b4030095d5897ebf4fa442a6 93 PANTHER PTHR11880 1 92 7.6E-53 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 DC74_RS18715 d5f03820b4030095d5897ebf4fa442a6 93 SUPERFAMILY SSF54570 3 85 3.14E-34 T 23-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 DC74_RS18715 d5f03820b4030095d5897ebf4fa442a6 93 Pfam PF00203 Ribosomal protein S19 3 83 2.7E-35 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 DC74_RS18715 d5f03820b4030095d5897ebf4fa442a6 93 PIRSF PIRSF002144 1 93 3.1E-30 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 DC74_RS18715 d5f03820b4030095d5897ebf4fa442a6 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 23-04-2016 IPR020934 Ribosomal protein S19 conserved site GO:0003723 DC74_RS18715 d5f03820b4030095d5897ebf4fa442a6 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 1.4E-23 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 DC74_RS18715 d5f03820b4030095d5897ebf4fa442a6 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 1.4E-23 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 DC74_RS18715 d5f03820b4030095d5897ebf4fa442a6 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 1.4E-23 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 DC74_RS18715 d5f03820b4030095d5897ebf4fa442a6 93 Gene3D G3DSA:3.30.860.10 1 92 5.3E-40 T 23-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 DC74_RS18715 d5f03820b4030095d5897ebf4fa442a6 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 3.7E-46 T 23-04-2016 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 DC74_RS18715 d5f03820b4030095d5897ebf4fa442a6 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.553 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 1.8E-30 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.8E-30 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 PRINTS PR00101 Aspartate carbamoyltransferase signature 291 305 1.8E-30 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 1.8E-30 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 1.8E-30 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 PRINTS PR00101 Aspartate carbamoyltransferase signature 267 272 1.8E-30 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 PANTHER PTHR11405 3 313 3.5E-136 T 23-04-2016 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 PANTHER PTHR11405:SF16 3 313 3.5E-136 T 23-04-2016 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 6.0E-19 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 6.0E-19 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 6.0E-19 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 6.0E-19 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 310 8.6E-93 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 SUPERFAMILY SSF53671 2 312 1.7E-93 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 162 309 1.8E-22 T 23-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 147 1.9E-40 T 23-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 Gene3D G3DSA:3.40.50.1370 2 142 3.2E-50 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 312 41.222 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09455 97a5f5f9f1ac6d880a9ab2b9ddc4c3c6 325 Gene3D G3DSA:3.40.50.1370 143 288 3.2E-48 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS31605 3affd80785f65f2468393de944b60664 506 SUPERFAMILY SSF75304 36 491 2.35E-118 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS31605 3affd80785f65f2468393de944b60664 506 PANTHER PTHR11895 37 491 1.5E-182 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS31605 3affd80785f65f2468393de944b60664 506 Pfam PF01425 Amidase 54 473 1.6E-107 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS31605 3affd80785f65f2468393de944b60664 506 Gene3D G3DSA:3.90.1300.10 38 492 3.7E-121 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS31605 3affd80785f65f2468393de944b60664 506 PANTHER PTHR11895:SF103 37 491 1.5E-182 T 23-04-2016 DC74_RS31605 3affd80785f65f2468393de944b60664 506 ProSitePatterns PS00571 Amidases signature. 179 210 - T 23-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS31590 ddd1516757abc6ee4a452a1cc3546c5a 366 PANTHER PTHR37958 1 366 1.1E-106 T 23-04-2016 DC74_RS31590 ddd1516757abc6ee4a452a1cc3546c5a 366 PANTHER PTHR37958:SF1 1 366 1.1E-106 T 23-04-2016 DC74_RS31590 ddd1516757abc6ee4a452a1cc3546c5a 366 Pfam PF01699 Sodium/calcium exchanger protein 222 363 6.7E-13 T 23-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 DC74_RS31590 ddd1516757abc6ee4a452a1cc3546c5a 366 Pfam PF01699 Sodium/calcium exchanger protein 39 188 1.2E-14 T 23-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 DC74_RS04865 ebf8b200a38d5057f74ecfb0821228b1 315 Gene3D G3DSA:3.40.190.10 197 275 1.5E-13 T 23-04-2016 DC74_RS04865 ebf8b200a38d5057f74ecfb0821228b1 315 PANTHER PTHR30346 10 315 2.5E-73 T 23-04-2016 DC74_RS04865 ebf8b200a38d5057f74ecfb0821228b1 315 Gene3D G3DSA:3.40.190.10 100 196 3.0E-25 T 23-04-2016 DC74_RS04865 ebf8b200a38d5057f74ecfb0821228b1 315 SUPERFAMILY SSF46785 13 120 6.82E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04865 ebf8b200a38d5057f74ecfb0821228b1 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 3.9E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS04865 ebf8b200a38d5057f74ecfb0821228b1 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 3.9E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS04865 ebf8b200a38d5057f74ecfb0821228b1 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 3.9E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS04865 ebf8b200a38d5057f74ecfb0821228b1 315 Gene3D G3DSA:1.10.10.10 13 94 9.0E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04865 ebf8b200a38d5057f74ecfb0821228b1 315 PANTHER PTHR30346:SF2 10 315 2.5E-73 T 23-04-2016 DC74_RS04865 ebf8b200a38d5057f74ecfb0821228b1 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 73 2.0E-19 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS04865 ebf8b200a38d5057f74ecfb0821228b1 315 SUPERFAMILY SSF53850 100 306 4.0E-29 T 23-04-2016 DC74_RS04865 ebf8b200a38d5057f74ecfb0821228b1 315 Pfam PF03466 LysR substrate binding domain 100 305 1.1E-28 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS09595 c1a0f17978f45b88c09f531f0f84f2e1 374 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 84 292 1.8E-52 T 23-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial DC74_RS09595 c1a0f17978f45b88c09f531f0f84f2e1 374 PANTHER PTHR30081 9 334 4.4E-64 T 23-04-2016 DC74_RS09595 c1a0f17978f45b88c09f531f0f84f2e1 374 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 46 295 8.1E-75 T 23-04-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 DC74_RS09595 c1a0f17978f45b88c09f531f0f84f2e1 374 SUPERFAMILY SSF82866 112 304 5.49E-28 T 23-04-2016 DC74_RS09595 c1a0f17978f45b88c09f531f0f84f2e1 374 Gene3D G3DSA:1.20.1640.10 111 305 1.0E-18 T 23-04-2016 DC74_RS09595 c1a0f17978f45b88c09f531f0f84f2e1 374 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 18 306 24.206 T 23-04-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 DC74_RS09595 c1a0f17978f45b88c09f531f0f84f2e1 374 PRINTS PR01755 Bacterial translocase SecF protein signature 238 253 7.3E-22 T 23-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial DC74_RS09595 c1a0f17978f45b88c09f531f0f84f2e1 374 PRINTS PR01755 Bacterial translocase SecF protein signature 203 221 7.3E-22 T 23-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial DC74_RS09595 c1a0f17978f45b88c09f531f0f84f2e1 374 PRINTS PR01755 Bacterial translocase SecF protein signature 155 169 7.3E-22 T 23-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial DC74_RS09595 c1a0f17978f45b88c09f531f0f84f2e1 374 PRINTS PR01755 Bacterial translocase SecF protein signature 45 60 7.3E-22 T 23-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial DC74_RS09595 c1a0f17978f45b88c09f531f0f84f2e1 374 Pfam PF02355 Protein export membrane protein 111 304 4.6E-65 T 23-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial DC74_RS09595 c1a0f17978f45b88c09f531f0f84f2e1 374 Pfam PF07549 SecD/SecF GG Motif 41 60 7.8E-5 T 23-04-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 122 331 2.0E-78 T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 SUPERFAMILY SSF51230 575 652 1.24E-20 T 23-04-2016 IPR011053 Single hybrid motif DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 Pfam PF00364 Biotin-requiring enzyme 586 651 2.7E-17 T 23-04-2016 IPR000089 Biotin/lipoyl attachment DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 295 302 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 SUPERFAMILY SSF52440 8 120 2.01E-46 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 Gene3D G3DSA:2.40.50.100 584 652 8.6E-23 T 23-04-2016 DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 Pfam PF00289 Biotin carboxylase, N-terminal domain 9 117 2.0E-42 T 23-04-2016 IPR005481 Biotin carboxylase-like, N-terminal domain DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 Gene3D G3DSA:3.30.470.20 210 453 4.6E-97 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 SMART SM00878 345 451 1.4E-52 T 23-04-2016 IPR005482 Biotin carboxylase, C-terminal DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 SUPERFAMILY SSF56059 90 357 2.3E-69 T 23-04-2016 DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 Gene3D G3DSA:3.30.1490.20 137 208 5.7E-26 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 PANTHER PTHR18866:SF102 9 657 0.0 T 23-04-2016 DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 SUPERFAMILY SSF51246 340 454 6.28E-37 T 23-04-2016 IPR011054 Rudiment single hybrid motif DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 Gene3D G3DSA:3.40.50.20 10 136 3.9E-49 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 PANTHER PTHR18866 9 657 0.0 T 23-04-2016 DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 Pfam PF02785 Biotin carboxylase C-terminal domain 345 451 6.1E-35 T 23-04-2016 IPR005482 Biotin carboxylase, C-terminal DC74_RS15910 e9a5b425012c2eb3dd715360a35653ea 679 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 609 626 - T 23-04-2016 IPR001882 Biotin-binding site DC74_RS07670 d411f5e625ce653a2b36c4608312c3e1 177 SUPERFAMILY SSF55729 1 157 2.76E-35 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS07670 d411f5e625ce653a2b36c4608312c3e1 177 Gene3D G3DSA:3.40.630.30 1 170 3.2E-43 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS07670 d411f5e625ce653a2b36c4608312c3e1 177 Pfam PF13302 Acetyltransferase (GNAT) domain 8 150 1.9E-27 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS07670 d411f5e625ce653a2b36c4608312c3e1 177 PANTHER PTHR13256 1 155 1.6E-46 T 23-04-2016 DC74_RS07670 d411f5e625ce653a2b36c4608312c3e1 177 PANTHER PTHR13256:SF19 1 155 1.6E-46 T 23-04-2016 DC74_RS19865 7fdf95d5c7826aa3bf8bfe0b75e4f8de 137 PIRSF PIRSF017349 1 137 6.1E-67 T 23-04-2016 IPR014487 Protein of unknown function DUF3151 DC74_RS19865 7fdf95d5c7826aa3bf8bfe0b75e4f8de 137 Pfam PF11349 Protein of unknown function (DUF3151) 10 134 2.9E-59 T 23-04-2016 IPR014487 Protein of unknown function DUF3151 DC74_RS27050 d044678893a204d8c060e80b06c2ffe1 317 PANTHER PTHR11695 15 315 2.6E-78 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS27050 d044678893a204d8c060e80b06c2ffe1 317 PANTHER PTHR11695:SF605 15 315 2.6E-78 T 23-04-2016 DC74_RS27050 d044678893a204d8c060e80b06c2ffe1 317 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 130 151 - T 23-04-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 DC74_RS27050 d044678893a204d8c060e80b06c2ffe1 317 SUPERFAMILY SSF51735 103 281 1.58E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27050 d044678893a204d8c060e80b06c2ffe1 317 SMART SM00829 10 313 4.4E-25 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS27050 d044678893a204d8c060e80b06c2ffe1 317 Gene3D G3DSA:3.40.50.720 136 253 1.5E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27050 d044678893a204d8c060e80b06c2ffe1 317 SUPERFAMILY SSF50129 1 130 1.48E-28 T 23-04-2016 IPR011032 GroES-like DC74_RS27050 d044678893a204d8c060e80b06c2ffe1 317 Gene3D G3DSA:3.90.180.10 1 135 1.1E-34 T 23-04-2016 IPR011032 GroES-like DC74_RS27050 d044678893a204d8c060e80b06c2ffe1 317 Pfam PF00107 Zinc-binding dehydrogenase 141 268 1.9E-28 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 Pfam PF14759 Reductase C-terminal 347 419 2.0E-10 T 23-04-2016 IPR028202 Reductase, C-terminal DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.8E-19 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 254 1.8E-19 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 1.8E-19 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.8E-19 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.8E-19 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PANTHER PTHR22912 337 371 4.3E-80 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PANTHER PTHR22912 1 315 4.3E-80 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 SUPERFAMILY SSF51905 146 315 3.42E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 239 253 3.3E-17 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.3E-17 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 3.3E-17 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 3.3E-17 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 SUPERFAMILY SSF55424 339 418 6.18E-16 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 Gene3D G3DSA:3.50.50.60 146 315 3.6E-35 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PANTHER PTHR22912:SF180 337 371 4.3E-80 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 PANTHER PTHR22912:SF180 1 315 4.3E-80 T 23-04-2016 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 Gene3D G3DSA:3.30.390.30 347 421 5.4E-14 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 307 3.3E-48 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 SUPERFAMILY SSF51905 2 192 2.11E-41 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33615 1c584a2c80c4e39575cad6c017709186 431 Gene3D G3DSA:3.50.50.60 3 118 3.6E-28 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39120 238e63b1ffcf699af13943e45b336a10 243 Gene3D G3DSA:1.10.10.60 153 189 1.4E-6 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39120 238e63b1ffcf699af13943e45b336a10 243 SMART SM00342 149 231 1.1E-4 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS39120 238e63b1ffcf699af13943e45b336a10 243 PANTHER PTHR11019 153 239 1.4E-12 T 23-04-2016 DC74_RS39120 238e63b1ffcf699af13943e45b336a10 243 Pfam PF12833 Helix-turn-helix domain 156 231 1.5E-15 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS39120 238e63b1ffcf699af13943e45b336a10 243 PANTHER PTHR11019:SF126 153 239 1.4E-12 T 23-04-2016 DC74_RS18905 46efb32024142a8b5273c971e521301d 125 PANTHER PTHR11434:SF0 2 104 5.6E-57 T 23-04-2016 DC74_RS18905 46efb32024142a8b5273c971e521301d 125 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 97 2.4E-25 T 23-04-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 DC74_RS18905 46efb32024142a8b5273c971e521301d 125 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 101 18.69 T 23-04-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 DC74_RS18905 46efb32024142a8b5273c971e521301d 125 PANTHER PTHR11434 2 104 5.6E-57 T 23-04-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 Gene3D G3DSA:1.10.510.10 126 279 1.9E-40 T 23-04-2016 DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 SMART SM00458 491 611 1.6E-4 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 Gene3D G3DSA:3.30.200.20 27 125 8.1E-8 T 23-04-2016 DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 SUPERFAMILY SSF50370 490 608 3.05E-16 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 SUPERFAMILY SSF56112 27 284 3.59E-56 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 Pfam PF00069 Protein kinase domain 32 279 6.8E-33 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 SMART SM00220 29 280 8.7E-33 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 Gene3D G3DSA:2.80.10.50 489 550 5.2E-7 T 23-04-2016 DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 35 56 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 PANTHER PTHR24362 21 367 2.2E-84 T 23-04-2016 DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 147 159 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 Gene3D G3DSA:2.80.10.50 551 609 8.6E-7 T 23-04-2016 DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 PANTHER PTHR24362:SF247 21 367 2.2E-84 T 23-04-2016 DC74_RS01850 f09439c7f74adcfb47c4553c1a57387b 611 Pfam PF00652 Ricin-type beta-trefoil lectin domain 495 608 3.4E-10 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 PANTHER PTHR30603 158 514 2.5E-210 T 23-04-2016 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 Pfam PF00140 Sigma-70 factor, region 1.2 216 249 8.0E-17 T 23-04-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 SUPERFAMILY SSF88659 412 513 2.62E-27 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 Pfam PF04539 Sigma-70 region 3 360 436 1.1E-28 T 23-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 SUPERFAMILY SSF88659 354 427 3.92E-21 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 Pfam PF04542 Sigma-70 region 2 281 350 3.1E-22 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 118 514 31.91 T 23-04-2016 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 277 502 2.0E-36 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 Pfam PF04545 Sigma-70, region 4 449 502 2.9E-18 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 Gene3D G3DSA:1.10.10.10 354 405 3.9E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 PANTHER PTHR30603:SF0 158 514 2.5E-210 T 23-04-2016 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 PRINTS PR00046 Major sigma-70 factor signature 305 318 6.9E-29 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 PRINTS PR00046 Major sigma-70 factor signature 329 337 6.9E-29 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 PRINTS PR00046 Major sigma-70 factor signature 453 465 6.9E-29 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 PRINTS PR00046 Major sigma-70 factor signature 474 489 6.9E-29 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 PRINTS PR00046 Major sigma-70 factor signature 489 500 6.9E-29 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 474 500 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 305 318 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 277 513 9.0E-113 T 23-04-2016 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 SUPERFAMILY SSF88946 213 351 7.85E-54 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 Gene3D G3DSA:1.10.10.10 443 514 2.0E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29005 b1e682ad7a2cb49d1a152807d793281e 514 Gene3D G3DSA:1.10.601.10 119 350 2.8E-69 T 23-04-2016 DC74_RS17925 27048aaa901aa4e7f8de605ce8cc5b77 343 PIRSF PIRSF005739 5 342 1.2E-54 T 23-04-2016 IPR016461 O-methyltransferase COMT-type GO:0008168 DC74_RS17925 27048aaa901aa4e7f8de605ce8cc5b77 343 SUPERFAMILY SSF53335 100 340 1.58E-53 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS17925 27048aaa901aa4e7f8de605ce8cc5b77 343 Pfam PF00891 O-methyltransferase 108 326 4.3E-42 T 23-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 DC74_RS17925 27048aaa901aa4e7f8de605ce8cc5b77 343 PANTHER PTHR11746 10 339 5.6E-90 T 23-04-2016 DC74_RS17925 27048aaa901aa4e7f8de605ce8cc5b77 343 SUPERFAMILY SSF46785 16 98 5.16E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17925 27048aaa901aa4e7f8de605ce8cc5b77 343 Gene3D G3DSA:1.10.10.10 16 104 8.3E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17925 27048aaa901aa4e7f8de605ce8cc5b77 343 Gene3D G3DSA:3.40.50.150 105 341 4.4E-71 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS12410 166d44c4b774e5e3025495f134db1008 171 Gene3D G3DSA:3.90.960.10 18 169 5.7E-58 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 DC74_RS12410 166d44c4b774e5e3025495f134db1008 171 PANTHER PTHR30411 18 170 3.1E-62 T 23-04-2016 DC74_RS12410 166d44c4b774e5e3025495f134db1008 171 PANTHER PTHR30411:SF0 18 170 3.1E-62 T 23-04-2016 DC74_RS12410 166d44c4b774e5e3025495f134db1008 171 PIRSF PIRSF006181 13 171 6.6E-51 T 23-04-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC DC74_RS12410 166d44c4b774e5e3025495f134db1008 171 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 18 169 3.3E-54 T 23-04-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC DC74_RS12410 166d44c4b774e5e3025495f134db1008 171 SUPERFAMILY SSF55826 18 168 5.1E-43 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 DC74_RS12410 166d44c4b774e5e3025495f134db1008 171 Pfam PF04073 Aminoacyl-tRNA editing domain 42 158 9.0E-28 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 DC74_RS26265 362513477a4ee5d5647b16fed670d4fa 364 SUPERFAMILY SSF54211 236 345 9.86E-17 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS26265 362513477a4ee5d5647b16fed670d4fa 364 Gene3D G3DSA:2.30.42.10 142 195 5.3E-11 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS26265 362513477a4ee5d5647b16fed670d4fa 364 SUPERFAMILY SSF50156 141 253 2.56E-12 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS26265 362513477a4ee5d5647b16fed670d4fa 364 PANTHER PTHR10046 213 351 4.2E-49 T 23-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 DC74_RS26265 362513477a4ee5d5647b16fed670d4fa 364 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 252 333 1.5E-6 T 23-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 DC74_RS26265 362513477a4ee5d5647b16fed670d4fa 364 Gene3D G3DSA:3.30.230.10 249 345 1.0E-18 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS26265 362513477a4ee5d5647b16fed670d4fa 364 Pfam PF13180 PDZ domain 138 194 7.0E-9 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS26265 362513477a4ee5d5647b16fed670d4fa 364 PANTHER PTHR10046:SF48 213 351 4.2E-49 T 23-04-2016 DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 PANTHER PTHR24322 164 195 3.7E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 PANTHER PTHR24322 18 147 3.7E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 7.0E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 7.0E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 7.0E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 7.0E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 7.0E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 7.0E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 8.1E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 8.1E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 8.1E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 195 0.0076 T 23-04-2016 DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 Gene3D G3DSA:3.40.50.720 11 255 6.1E-73 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 253 1.1E-54 T 23-04-2016 DC74_RS25180 f6c6ac57a00f5eab04842ed678d4323a 255 SUPERFAMILY SSF51735 11 254 8.0E-70 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10095 cd2ab8e5b284ec55e326dd5e16698fda 287 PANTHER PTHR12029 4 273 5.8E-55 T 23-04-2016 DC74_RS10095 cd2ab8e5b284ec55e326dd5e16698fda 287 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 34 108 1.6E-9 T 23-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 DC74_RS10095 cd2ab8e5b284ec55e326dd5e16698fda 287 Pfam PF00588 SpoU rRNA Methylase family 122 266 1.7E-36 T 23-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 DC74_RS10095 cd2ab8e5b284ec55e326dd5e16698fda 287 SUPERFAMILY SSF75217 100 276 9.81E-41 T 23-04-2016 IPR029028 Alpha/beta knot methyltransferases DC74_RS10095 cd2ab8e5b284ec55e326dd5e16698fda 287 Gene3D G3DSA:3.30.1330.30 6 107 2.2E-27 T 23-04-2016 IPR029064 50S ribosomal protein L30e-like DC74_RS10095 cd2ab8e5b284ec55e326dd5e16698fda 287 Gene3D G3DSA:3.40.1280.10 118 273 1.7E-47 T 23-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DC74_RS10095 cd2ab8e5b284ec55e326dd5e16698fda 287 SUPERFAMILY SSF55315 6 107 1.02E-18 T 23-04-2016 IPR029064 50S ribosomal protein L30e-like DC74_RS10095 cd2ab8e5b284ec55e326dd5e16698fda 287 SMART SM00967 33 111 1.5E-11 T 23-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 DC74_RS18590 7ad6f209257d5ddfd186a68709cff8ab 283 Gene3D G3DSA:3.30.70.660 120 256 5.2E-36 T 23-04-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS18590 7ad6f209257d5ddfd186a68709cff8ab 283 PIRSF PIRSF001430 10 275 1.8E-75 T 23-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS18590 7ad6f209257d5ddfd186a68709cff8ab 283 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 258 30.755 T 23-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS18590 7ad6f209257d5ddfd186a68709cff8ab 283 PANTHER PTHR11142 2 273 2.8E-82 T 23-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS18590 7ad6f209257d5ddfd186a68709cff8ab 283 SUPERFAMILY SSF55120 9 265 3.02E-72 T 23-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS18590 7ad6f209257d5ddfd186a68709cff8ab 283 Pfam PF01416 tRNA pseudouridine synthase 157 259 5.5E-22 T 23-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS18590 7ad6f209257d5ddfd186a68709cff8ab 283 Pfam PF01416 tRNA pseudouridine synthase 17 116 1.1E-6 T 23-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS18590 7ad6f209257d5ddfd186a68709cff8ab 283 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 12 252 6.1E-51 T 23-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS18590 7ad6f209257d5ddfd186a68709cff8ab 283 PANTHER PTHR11142:SF0 2 273 2.8E-82 T 23-04-2016 DC74_RS18590 7ad6f209257d5ddfd186a68709cff8ab 283 Gene3D G3DSA:3.30.70.580 10 118 5.7E-34 T 23-04-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00359 B-class P450 signature 146 162 1.5E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00359 B-class P450 signature 163 178 1.5E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00359 B-class P450 signature 299 326 1.5E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00359 B-class P450 signature 327 342 1.5E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00359 B-class P450 signature 358 369 1.5E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00359 B-class P450 signature 281 292 1.5E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00359 B-class P450 signature 349 358 1.5E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00359 B-class P450 signature 200 222 1.5E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00359 B-class P450 signature 98 109 1.5E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00385 P450 superfamily signature 349 358 5.3E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00385 P450 superfamily signature 358 369 5.3E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00385 P450 superfamily signature 246 263 5.3E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PRINTS PR00385 P450 superfamily signature 281 292 5.3E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 351 360 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 Gene3D G3DSA:1.10.630.10 22 409 3.9E-125 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 PANTHER PTHR11712 1 409 2.9E-93 T 23-04-2016 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 Pfam PF00067 Cytochrome P450 196 380 2.6E-28 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 Pfam PF00067 Cytochrome P450 88 170 4.4E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33605 8b8d3f837a8d831e8ba19677df753322 409 SUPERFAMILY SSF48264 23 409 1.31E-97 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS26185 975b634417549466db9ccaae7cd0df97 311 Pfam PF00293 NUDIX domain 174 281 2.8E-19 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS26185 975b634417549466db9ccaae7cd0df97 311 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 43 137 7.8E-13 T 23-04-2016 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 DC74_RS26185 975b634417549466db9ccaae7cd0df97 311 Gene3D G3DSA:3.90.79.10 137 305 1.6E-50 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS26185 975b634417549466db9ccaae7cd0df97 311 PANTHER PTHR11383:SF4 1 309 2.3E-171 T 23-04-2016 DC74_RS26185 975b634417549466db9ccaae7cd0df97 311 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 141 170 2.3E-13 T 23-04-2016 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 DC74_RS26185 975b634417549466db9ccaae7cd0df97 311 SUPERFAMILY SSF55811 123 306 5.28E-48 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS26185 975b634417549466db9ccaae7cd0df97 311 PANTHER PTHR11383 1 309 2.3E-171 T 23-04-2016 DC74_RS02875 b1b7d23aac57e100caa85d8dad032c5b 865 Gene3D G3DSA:3.50.30.10 762 861 2.3E-25 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS02875 b1b7d23aac57e100caa85d8dad032c5b 865 PANTHER PTHR22931 1 383 2.3E-219 T 23-04-2016 DC74_RS02875 b1b7d23aac57e100caa85d8dad032c5b 865 PANTHER PTHR22931 774 863 2.3E-219 T 23-04-2016 DC74_RS02875 b1b7d23aac57e100caa85d8dad032c5b 865 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 316 2.5E-94 T 23-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 DC74_RS02875 b1b7d23aac57e100caa85d8dad032c5b 865 Pfam PF00391 PEP-utilising enzyme, mobile domain 788 859 6.8E-20 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS02875 b1b7d23aac57e100caa85d8dad032c5b 865 Gene3D G3DSA:3.30.470.20 188 335 1.3E-46 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS02875 b1b7d23aac57e100caa85d8dad032c5b 865 SUPERFAMILY SSF52009 762 863 7.46E-26 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS02875 b1b7d23aac57e100caa85d8dad032c5b 865 Gene3D G3DSA:3.30.1490.20 4 187 2.5E-62 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS02875 b1b7d23aac57e100caa85d8dad032c5b 865 PANTHER PTHR22931:SF25 1 383 2.3E-219 T 23-04-2016 DC74_RS02875 b1b7d23aac57e100caa85d8dad032c5b 865 PANTHER PTHR22931:SF25 774 863 2.3E-219 T 23-04-2016 DC74_RS02875 b1b7d23aac57e100caa85d8dad032c5b 865 SUPERFAMILY SSF56059 3 342 9.42E-96 T 23-04-2016 DC74_RS01775 4e9f9bc66dd506d7941cab22ff4b1cf5 717 Pfam PF00982 Glycosyltransferase family 20 333 705 2.1E-75 T 23-04-2016 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 DC74_RS01775 4e9f9bc66dd506d7941cab22ff4b1cf5 717 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 148 217 3.6E-12 T 23-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 DC74_RS01775 4e9f9bc66dd506d7941cab22ff4b1cf5 717 SUPERFAMILY SSF53756 261 705 3.33E-90 T 23-04-2016 DC74_RS01775 4e9f9bc66dd506d7941cab22ff4b1cf5 717 Gene3D G3DSA:3.40.50.2000 506 687 1.0E-45 T 23-04-2016 DC74_RS01775 4e9f9bc66dd506d7941cab22ff4b1cf5 717 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 20 250 5.3E-45 T 23-04-2016 IPR006380 Sucrose-phosphatase, N-terminal DC74_RS01775 4e9f9bc66dd506d7941cab22ff4b1cf5 717 SUPERFAMILY SSF56784 20 229 9.09E-29 T 23-04-2016 IPR023214 HAD-like domain DC74_RS01775 4e9f9bc66dd506d7941cab22ff4b1cf5 717 Gene3D G3DSA:3.40.50.2000 260 465 6.0E-45 T 23-04-2016 DC74_RS01775 4e9f9bc66dd506d7941cab22ff4b1cf5 717 PANTHER PTHR10788 335 706 2.0E-83 T 23-04-2016 DC74_RS01775 4e9f9bc66dd506d7941cab22ff4b1cf5 717 Gene3D G3DSA:3.40.50.1000 20 98 1.7E-26 T 23-04-2016 IPR023214 HAD-like domain DC74_RS01775 4e9f9bc66dd506d7941cab22ff4b1cf5 717 Gene3D G3DSA:3.40.50.1000 167 247 1.7E-26 T 23-04-2016 IPR023214 HAD-like domain DC74_RS01775 4e9f9bc66dd506d7941cab22ff4b1cf5 717 PANTHER PTHR10788:SF6 335 706 2.0E-83 T 23-04-2016 DC74_RS28050 4e0f25c7d6ecc59d24bb5b6f9d9366c2 334 Pfam PF00296 Luciferase-like monooxygenase 27 272 1.2E-32 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS28050 4e0f25c7d6ecc59d24bb5b6f9d9366c2 334 PANTHER PTHR30137:SF8 1 332 1.5E-29 T 23-04-2016 DC74_RS28050 4e0f25c7d6ecc59d24bb5b6f9d9366c2 334 Gene3D G3DSA:3.20.20.30 19 333 8.1E-64 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS28050 4e0f25c7d6ecc59d24bb5b6f9d9366c2 334 PANTHER PTHR30137 1 332 1.5E-29 T 23-04-2016 DC74_RS28050 4e0f25c7d6ecc59d24bb5b6f9d9366c2 334 SUPERFAMILY SSF51679 19 333 2.75E-54 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS39660 d9d51b2c205b0b3a7b4b7a6acf56a464 187 Gene3D G3DSA:3.40.630.30 2 186 6.8E-45 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS39660 d9d51b2c205b0b3a7b4b7a6acf56a464 187 PANTHER PTHR13256:SF10 1 187 9.7E-33 T 23-04-2016 DC74_RS39660 d9d51b2c205b0b3a7b4b7a6acf56a464 187 Pfam PF13302 Acetyltransferase (GNAT) domain 9 153 2.0E-28 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS39660 d9d51b2c205b0b3a7b4b7a6acf56a464 187 PANTHER PTHR13256 1 187 9.7E-33 T 23-04-2016 DC74_RS39660 d9d51b2c205b0b3a7b4b7a6acf56a464 187 SUPERFAMILY SSF55729 2 154 2.21E-34 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00359 B-class P450 signature 269 280 7.8E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00359 B-class P450 signature 314 329 7.8E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00359 B-class P450 signature 152 167 7.8E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00359 B-class P450 signature 135 151 7.8E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00359 B-class P450 signature 344 355 7.8E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00359 B-class P450 signature 335 344 7.8E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00359 B-class P450 signature 188 210 7.8E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00359 B-class P450 signature 286 313 7.8E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00359 B-class P450 signature 88 99 7.8E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00385 P450 superfamily signature 269 280 3.8E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00385 P450 superfamily signature 335 344 3.8E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00385 P450 superfamily signature 234 251 3.8E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PRINTS PR00385 P450 superfamily signature 344 355 3.8E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 Gene3D G3DSA:1.10.630.10 8 395 2.2E-122 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 Pfam PF00067 Cytochrome P450 171 364 1.0E-24 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 PANTHER PTHR11712 21 395 4.3E-93 T 23-04-2016 DC74_RS31865 6ae206f127125ad9ee06c87aa119be65 395 SUPERFAMILY SSF48264 10 395 3.27E-95 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS24350 f755695ee8b3db2a9cc0c9ca9585b2e3 237 Pfam PF00877 NlpC/P60 family 137 225 5.1E-22 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS24350 f755695ee8b3db2a9cc0c9ca9585b2e3 237 PANTHER PTHR21666 115 226 2.6E-34 T 23-04-2016 DC74_RS24350 f755695ee8b3db2a9cc0c9ca9585b2e3 237 Gene3D G3DSA:3.90.1720.10 118 226 1.8E-39 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS24350 f755695ee8b3db2a9cc0c9ca9585b2e3 237 SUPERFAMILY SSF54001 115 229 1.32E-37 T 23-04-2016 DC74_RS26635 25e8a5936e12d21be4f2a61a7c00cea8 327 PANTHER PTHR18966 58 311 6.7E-49 T 23-04-2016 DC74_RS26635 25e8a5936e12d21be4f2a61a7c00cea8 327 SUPERFAMILY SSF53850 20 314 1.25E-48 T 23-04-2016 DC74_RS26635 25e8a5936e12d21be4f2a61a7c00cea8 327 PANTHER PTHR18966:SF191 58 311 6.7E-49 T 23-04-2016 DC74_RS26635 25e8a5936e12d21be4f2a61a7c00cea8 327 Gene3D G3DSA:3.40.190.10 31 191 3.3E-36 T 23-04-2016 DC74_RS26635 25e8a5936e12d21be4f2a61a7c00cea8 327 Gene3D G3DSA:3.40.190.10 192 269 1.5E-16 T 23-04-2016 DC74_RS26635 25e8a5936e12d21be4f2a61a7c00cea8 327 SMART SM00062 73 315 3.5E-41 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS26635 25e8a5936e12d21be4f2a61a7c00cea8 327 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 74 312 7.7E-54 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SUPERFAMILY SSF50998 1561 1874 1.8E-78 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Gene3D G3DSA:2.130.10.10 1421 1690 5.8E-74 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF00805 Pentapeptide repeats (8 copies) 1113 1152 5.1E-9 T 23-04-2016 IPR001646 Pentapeptide repeat DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF00805 Pentapeptide repeats (8 copies) 1153 1191 1.8E-12 T 23-04-2016 IPR001646 Pentapeptide repeat DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SUPERFAMILY SSF56300 327 454 6.0E-17 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SUPERFAMILY SSF56300 230 300 6.0E-17 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Gene3D G3DSA:3.60.21.10 245 448 3.1E-15 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1447 1486 1.6E-12 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1277 1314 2.0E-8 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1401 1444 2.1E-5 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1748 1787 1.1E-7 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1788 1827 4.3E-6 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1317 1356 4.1E-4 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1664 1703 2.8 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1489 1528 0.013 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1580 1619 6.8E-10 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1622 1661 0.0013 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1706 1745 5.9E-8 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1359 1398 2.9E-7 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1537 1577 0.056 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00320 1830 1869 3.5E-13 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Gene3D G3DSA:3.40.50.300 678 846 3.8E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 PANTHER PTHR22847 1252 1786 1.1E-121 T 23-04-2016 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 PANTHER PTHR22847 1808 1874 1.1E-121 T 23-04-2016 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SUPERFAMILY SSF52200 14 123 8.89E-25 T 23-04-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SUPERFAMILY SSF141571 1107 1201 1.26E-26 T 23-04-2016 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF12894 Anaphase-promoting complex subunit 4 WD40 domain 1252 1329 1.1E-5 T 23-04-2016 IPR024977 Anaphase-promoting complex subunit 4, WD40 domain DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF12894 Anaphase-promoting complex subunit 4 WD40 domain 1686 1768 7.4E-8 T 23-04-2016 IPR024977 Anaphase-promoting complex subunit 4, WD40 domain DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF05729 NACHT domain 712 870 1.9E-10 T 23-04-2016 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SUPERFAMILY SSF52540 678 847 1.07E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SUPERFAMILY SSF50978 1252 1528 6.77E-73 T 23-04-2016 IPR017986 WD40-repeat-containing domain GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 SMART SM00255 13 253 0.0026 T 23-04-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF13676 TIR domain 16 123 3.3E-25 T 23-04-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Gene3D G3DSA:2.130.10.10 1691 1871 2.8E-57 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 PANTHER PTHR22847:SF50 1252 1786 1.1E-121 T 23-04-2016 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 PANTHER PTHR22847:SF50 1808 1874 1.1E-121 T 23-04-2016 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1856 1870 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1648 1662 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1814 1828 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1606 1620 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1343 1357 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1564 1578 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 PRINTS PR00320 G protein beta WD-40 repeat signature 1856 1870 5.9E-6 T 23-04-2016 IPR020472 G-protein beta WD-40 repeat DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 PRINTS PR00320 G protein beta WD-40 repeat signature 1301 1315 5.9E-6 T 23-04-2016 IPR020472 G-protein beta WD-40 repeat DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 PRINTS PR00320 G protein beta WD-40 repeat signature 1473 1487 5.9E-6 T 23-04-2016 IPR020472 G-protein beta WD-40 repeat DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Gene3D G3DSA:3.40.50.10140 15 126 1.8E-21 T 23-04-2016 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF00400 WD domain, G-beta repeat 1581 1619 3.9E-7 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF00400 WD domain, G-beta repeat 1402 1443 4.5E-4 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF00400 WD domain, G-beta repeat 1836 1869 3.8E-9 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF00400 WD domain, G-beta repeat 1449 1486 2.5E-9 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF00400 WD domain, G-beta repeat 1360 1398 0.0048 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF00400 WD domain, G-beta repeat 1503 1527 0.18 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Pfam PF00400 WD domain, G-beta repeat 1790 1827 0.0062 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS07760 52757e8f60eca0f99dd385b44a9738ff 1940 Gene3D G3DSA:2.130.10.10 1252 1420 3.2E-53 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 Pfam PF00391 PEP-utilising enzyme, mobile domain 796 867 1.6E-22 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 PANTHER PTHR22931:SF7 284 395 3.0E-109 T 23-04-2016 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 PANTHER PTHR22931:SF7 781 870 3.0E-109 T 23-04-2016 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 PANTHER PTHR22931:SF7 4 262 3.0E-109 T 23-04-2016 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 338 4.1E-74 T 23-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 Gene3D G3DSA:3.30.1490.20 4 184 5.5E-46 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 Gene3D G3DSA:3.50.30.10 790 870 3.4E-27 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 SUPERFAMILY SSF56059 2 344 1.13E-73 T 23-04-2016 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 Gene3D G3DSA:3.30.470.20 185 341 1.9E-38 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 SUPERFAMILY SSF52009 767 870 6.93E-28 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 PANTHER PTHR22931 284 395 3.0E-109 T 23-04-2016 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 PANTHER PTHR22931 781 870 3.0E-109 T 23-04-2016 DC74_RS05620 738cd9c6eea7bd07ff726df08c491594 870 PANTHER PTHR22931 4 262 3.0E-109 T 23-04-2016 DC74_RS02530 34a868f64b72abe5ff0b801fd7b979bc 404 Gene3D G3DSA:3.30.565.10 300 393 1.2E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS02530 34a868f64b72abe5ff0b801fd7b979bc 404 PIRSF PIRSF037434 1 398 9.2E-114 T 23-04-2016 IPR017205 Signal transduction histidine kinase, ChrS DC74_RS02530 34a868f64b72abe5ff0b801fd7b979bc 404 PANTHER PTHR24421:SF24 62 404 1.8E-100 T 23-04-2016 DC74_RS02530 34a868f64b72abe5ff0b801fd7b979bc 404 SUPERFAMILY SSF55874 275 391 1.57E-17 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS02530 34a868f64b72abe5ff0b801fd7b979bc 404 PANTHER PTHR24421 62 404 1.8E-100 T 23-04-2016 DC74_RS02530 34a868f64b72abe5ff0b801fd7b979bc 404 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 297 392 4.7E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS02530 34a868f64b72abe5ff0b801fd7b979bc 404 Pfam PF07730 Histidine kinase 176 243 2.8E-16 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS12280 067a51b9168af365bee2b84e650b2fc3 388 Pfam PF03747 ADP-ribosylglycohydrolase 10 330 5.3E-47 T 23-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 DC74_RS12280 067a51b9168af365bee2b84e650b2fc3 388 PANTHER PTHR16222:SF12 4 332 5.1E-64 T 23-04-2016 DC74_RS12280 067a51b9168af365bee2b84e650b2fc3 388 PANTHER PTHR16222 4 332 5.1E-64 T 23-04-2016 DC74_RS12280 067a51b9168af365bee2b84e650b2fc3 388 SUPERFAMILY SSF101478 271 343 3.92E-43 T 23-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 DC74_RS12280 067a51b9168af365bee2b84e650b2fc3 388 SUPERFAMILY SSF101478 3 240 3.92E-43 T 23-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 ProSitePatterns PS00737 Thiolases signature 2. 350 366 - T 23-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 PANTHER PTHR18919 252 404 9.2E-254 T 23-04-2016 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 Pfam PF00108 Thiolase, N-terminal domain 7 230 8.6E-43 T 23-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 PIRSF PIRSF000429 2 404 1.1E-109 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 SUPERFAMILY SSF53901 282 403 1.27E-45 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 PANTHER PTHR18919 2 230 9.2E-254 T 23-04-2016 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 Gene3D G3DSA:3.40.47.10 148 186 6.2E-60 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 Gene3D G3DSA:3.40.47.10 288 403 6.2E-60 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 ProSitePatterns PS00099 Thiolases active site. 385 398 - T 23-04-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 SUPERFAMILY SSF53901 3 278 4.26E-63 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 402 3.3E-136 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 PANTHER PTHR18919:SF12 252 404 9.2E-254 T 23-04-2016 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 PANTHER PTHR18919:SF12 2 230 9.2E-254 T 23-04-2016 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 Pfam PF02803 Thiolase, C-terminal domain 282 403 4.3E-48 T 23-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 Gene3D G3DSA:3.40.47.10 187 287 1.6E-55 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS33020 ad31d1d0e4200c2ab8e13f7644d2626c 404 Gene3D G3DSA:3.40.47.10 5 128 1.6E-55 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS35370 aee54d8af593bbdc747cba5ab26a88b1 493 Pfam PF13520 Amino acid permease 20 421 1.2E-43 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS35370 aee54d8af593bbdc747cba5ab26a88b1 493 PANTHER PTHR11785 10 433 4.4E-43 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS35370 aee54d8af593bbdc747cba5ab26a88b1 493 PIRSF PIRSF006060 5 488 9.1E-57 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS19875 ec3a92557645dd8e5800e77717931ab7 510 PANTHER PTHR23501 20 468 4.6E-121 T 23-04-2016 DC74_RS19875 ec3a92557645dd8e5800e77717931ab7 510 SUPERFAMILY SSF103473 16 205 4.84E-69 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS19875 ec3a92557645dd8e5800e77717931ab7 510 SUPERFAMILY SSF103473 258 468 4.84E-69 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS19875 ec3a92557645dd8e5800e77717931ab7 510 Pfam PF07690 Major Facilitator Superfamily 27 420 7.7E-54 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS19875 ec3a92557645dd8e5800e77717931ab7 510 Gene3D G3DSA:1.20.1250.20 21 202 7.9E-35 T 23-04-2016 DC74_RS19875 ec3a92557645dd8e5800e77717931ab7 510 Gene3D G3DSA:1.20.1250.20 270 469 2.4E-15 T 23-04-2016 DC74_RS19875 ec3a92557645dd8e5800e77717931ab7 510 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 422 1.1E-77 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS24055 75d061995a1dce0ab748f0eab17d0e1f 295 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 23-04-2016 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 DC74_RS24055 75d061995a1dce0ab748f0eab17d0e1f 295 Gene3D G3DSA:3.40.50.720 2 163 3.3E-62 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS24055 75d061995a1dce0ab748f0eab17d0e1f 295 PIRSF PIRSF000103 1 290 2.0E-85 T 23-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 DC74_RS24055 75d061995a1dce0ab748f0eab17d0e1f 295 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 4 290 7.8E-128 T 23-04-2016 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 DC74_RS24055 75d061995a1dce0ab748f0eab17d0e1f 295 Gene3D G3DSA:1.10.1040.10 165 290 3.4E-39 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS24055 75d061995a1dce0ab748f0eab17d0e1f 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 283 2.5E-37 T 23-04-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 DC74_RS24055 75d061995a1dce0ab748f0eab17d0e1f 295 SUPERFAMILY SSF48179 163 289 5.55E-35 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS24055 75d061995a1dce0ab748f0eab17d0e1f 295 SUPERFAMILY SSF51735 1 162 3.02E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS24055 75d061995a1dce0ab748f0eab17d0e1f 295 PANTHER PTHR22981 1 290 1.3E-106 T 23-04-2016 DC74_RS24055 75d061995a1dce0ab748f0eab17d0e1f 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 5.7E-54 T 23-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 DC74_RS08075 5b4ccf462ace56f45519233b2bf3098c 961 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 20 953 0.0 T 23-04-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2 DC74_RS08075 5b4ccf462ace56f45519233b2bf3098c 961 Gene3D G3DSA:3.40.640.10 94 309 7.8E-16 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS08075 5b4ccf462ace56f45519233b2bf3098c 961 Gene3D G3DSA:3.40.640.10 505 743 2.0E-39 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS08075 5b4ccf462ace56f45519233b2bf3098c 961 Pfam PF02347 Glycine cleavage system P-protein 19 445 5.2E-180 T 23-04-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 DC74_RS08075 5b4ccf462ace56f45519233b2bf3098c 961 Pfam PF02347 Glycine cleavage system P-protein 453 736 5.4E-10 T 23-04-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 DC74_RS08075 5b4ccf462ace56f45519233b2bf3098c 961 SUPERFAMILY SSF53383 20 440 7.7E-102 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS08075 5b4ccf462ace56f45519233b2bf3098c 961 PANTHER PTHR11773 1 960 0.0 T 23-04-2016 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 DC74_RS08075 5b4ccf462ace56f45519233b2bf3098c 961 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 11 959 25.725 T 23-04-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2 DC74_RS08075 5b4ccf462ace56f45519233b2bf3098c 961 PANTHER PTHR11773:SF1 1 960 0.0 T 23-04-2016 DC74_RS08075 5b4ccf462ace56f45519233b2bf3098c 961 SUPERFAMILY SSF53383 474 890 6.77E-98 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS08075 5b4ccf462ace56f45519233b2bf3098c 961 SUPERFAMILY SSF53383 932 955 6.77E-98 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS25030 2c4756a0e7aed6776ae50ca19c103e3b 207 Pfam PF10756 Bacterial PH domain 71 130 5.3E-9 T 23-04-2016 IPR019692 Protein of unknown function DUF2581 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 Gene3D G3DSA:3.40.190.100 418 541 7.4E-35 T 23-04-2016 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 Gene3D G3DSA:3.40.190.100 691 805 3.8E-33 T 23-04-2016 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 333 582 1.2E-65 T 23-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 609 853 4.6E-58 T 23-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 Gene3D G3DSA:1.10.3720.10 79 260 3.2E-41 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 SUPERFAMILY SSF53850 327 592 1.34E-71 T 23-04-2016 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 SUPERFAMILY SSF161098 84 265 1.14E-38 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 SUPERFAMILY SSF53850 609 862 1.69E-62 T 23-04-2016 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 PANTHER PTHR30177 363 586 2.7E-252 T 23-04-2016 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 PANTHER PTHR30177 2 270 2.7E-252 T 23-04-2016 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 Gene3D G3DSA:3.40.190.10 806 864 4.2E-50 T 23-04-2016 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 Gene3D G3DSA:3.40.190.10 329 414 1.5E-33 T 23-04-2016 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 Gene3D G3DSA:3.40.190.10 603 687 4.2E-50 T 23-04-2016 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 273 1.1E-25 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 PANTHER PTHR30177:SF2 363 586 2.7E-252 T 23-04-2016 DC74_RS10205 d0d9ec209a48cade97793f4c14f1dfa1 866 PANTHER PTHR30177:SF2 2 270 2.7E-252 T 23-04-2016 DC74_RS07180 f01fa6c8366d22e006115e7da50e7db7 342 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 340 56.822 T 23-04-2016 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378|UniPathway: UPA00046 DC74_RS07180 f01fa6c8366d22e006115e7da50e7db7 342 PANTHER PTHR11695:SF285 13 340 5.7E-130 T 23-04-2016 DC74_RS07180 f01fa6c8366d22e006115e7da50e7db7 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 133 7.0E-30 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS07180 f01fa6c8366d22e006115e7da50e7db7 342 Gene3D G3DSA:3.40.50.720 173 287 2.5E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07180 f01fa6c8366d22e006115e7da50e7db7 342 SUPERFAMILY SSF51735 142 297 1.45E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07180 f01fa6c8366d22e006115e7da50e7db7 342 PANTHER PTHR11695 13 340 5.7E-130 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS07180 f01fa6c8366d22e006115e7da50e7db7 342 Pfam PF00107 Zinc-binding dehydrogenase 174 301 2.1E-22 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS07180 f01fa6c8366d22e006115e7da50e7db7 342 Gene3D G3DSA:3.90.180.10 2 172 3.3E-44 T 23-04-2016 IPR011032 GroES-like DC74_RS07180 f01fa6c8366d22e006115e7da50e7db7 342 SUPERFAMILY SSF50129 2 173 3.96E-48 T 23-04-2016 IPR011032 GroES-like DC74_RS07180 f01fa6c8366d22e006115e7da50e7db7 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS40215 34211107d9aa9d918a17fae9f31e869d 493 SUPERFAMILY SSF52788 330 479 5.1E-26 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS40215 34211107d9aa9d918a17fae9f31e869d 493 SMART SM00226 330 483 1.1E-6 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS40215 34211107d9aa9d918a17fae9f31e869d 493 PANTHER PTHR11717 328 480 4.0E-23 T 23-04-2016 DC74_RS40215 34211107d9aa9d918a17fae9f31e869d 493 Gene3D G3DSA:3.40.50.270 330 480 9.2E-31 T 23-04-2016 DC74_RS40215 34211107d9aa9d918a17fae9f31e869d 493 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 332 474 1.9E-15 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS40215 34211107d9aa9d918a17fae9f31e869d 493 PANTHER PTHR11717:SF14 328 480 4.0E-23 T 23-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 DC74_RS34610 d31f63072ede3db66f2dc29b5ff21c7f 538 Gene3D G3DSA:3.60.21.10 152 536 3.4E-64 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS34610 d31f63072ede3db66f2dc29b5ff21c7f 538 Pfam PF00149 Calcineurin-like phosphoesterase 209 395 3.4E-12 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS34610 d31f63072ede3db66f2dc29b5ff21c7f 538 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 54 146 1.7E-18 T 23-04-2016 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 DC74_RS34610 d31f63072ede3db66f2dc29b5ff21c7f 538 SUPERFAMILY SSF56300 197 528 1.31E-39 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS34610 d31f63072ede3db66f2dc29b5ff21c7f 538 PANTHER PTHR22953 196 444 9.5E-87 T 23-04-2016 DC74_RS34610 d31f63072ede3db66f2dc29b5ff21c7f 538 PANTHER PTHR22953 53 169 9.5E-87 T 23-04-2016 DC74_RS34610 d31f63072ede3db66f2dc29b5ff21c7f 538 PANTHER PTHR22953 466 533 9.5E-87 T 23-04-2016 DC74_RS34610 d31f63072ede3db66f2dc29b5ff21c7f 538 SUPERFAMILY SSF49363 52 148 4.84E-22 T 23-04-2016 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 DC74_RS34610 d31f63072ede3db66f2dc29b5ff21c7f 538 PANTHER PTHR22953:SF0 196 444 9.5E-87 T 23-04-2016 DC74_RS34610 d31f63072ede3db66f2dc29b5ff21c7f 538 PANTHER PTHR22953:SF0 53 169 9.5E-87 T 23-04-2016 DC74_RS34610 d31f63072ede3db66f2dc29b5ff21c7f 538 PANTHER PTHR22953:SF0 466 533 9.5E-87 T 23-04-2016 DC74_RS34610 d31f63072ede3db66f2dc29b5ff21c7f 538 Gene3D G3DSA:2.60.40.380 56 149 9.2E-18 T 23-04-2016 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 DC74_RS37665 e19116615c6bf286a1ae2ec606d7769f 135 SUPERFAMILY SSF55298 2 134 2.2E-23 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS37665 e19116615c6bf286a1ae2ec606d7769f 135 Pfam PF01042 Endoribonuclease L-PSP 15 133 1.1E-16 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS37665 e19116615c6bf286a1ae2ec606d7769f 135 PANTHER PTHR11803 1 134 1.1E-49 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS37665 e19116615c6bf286a1ae2ec606d7769f 135 Gene3D G3DSA:3.30.1330.40 1 134 4.9E-30 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS37665 e19116615c6bf286a1ae2ec606d7769f 135 PANTHER PTHR11803:SF9 1 134 1.1E-49 T 23-04-2016 DC74_RS33175 e1d3e479e6ad4e14999800c90547a6ec 606 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 239 261 - T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS33175 e1d3e479e6ad4e14999800c90547a6ec 606 Pfam PF01066 CDP-alcohol phosphatidyltransferase 195 261 1.1E-8 T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS09070 ba2f049f749d475d9a0e172bb5d88098 402 PANTHER PTHR23517 12 393 1.2E-24 T 23-04-2016 DC74_RS09070 ba2f049f749d475d9a0e172bb5d88098 402 SUPERFAMILY SSF103473 2 370 1.03E-31 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS09070 ba2f049f749d475d9a0e172bb5d88098 402 Gene3D G3DSA:1.20.1250.20 2 160 3.5E-13 T 23-04-2016 DC74_RS09070 ba2f049f749d475d9a0e172bb5d88098 402 Gene3D G3DSA:1.20.1250.20 185 371 1.2E-8 T 23-04-2016 DC74_RS09070 ba2f049f749d475d9a0e172bb5d88098 402 Pfam PF07690 Major Facilitator Superfamily 5 335 3.5E-23 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS09245 ed0bd47958b1602f5dfcac980c3f4b0c 417 Gene3D G3DSA:1.20.1250.20 220 394 6.4E-13 T 23-04-2016 DC74_RS09245 ed0bd47958b1602f5dfcac980c3f4b0c 417 Pfam PF07690 Major Facilitator Superfamily 33 217 3.1E-14 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS09245 ed0bd47958b1602f5dfcac980c3f4b0c 417 SUPERFAMILY SSF103473 12 394 1.15E-40 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS09245 ed0bd47958b1602f5dfcac980c3f4b0c 417 PANTHER PTHR23514:SF13 17 417 1.1E-129 T 23-04-2016 DC74_RS09245 ed0bd47958b1602f5dfcac980c3f4b0c 417 PANTHER PTHR23514 17 417 1.1E-129 T 23-04-2016 DC74_RS09245 ed0bd47958b1602f5dfcac980c3f4b0c 417 Gene3D G3DSA:1.20.1250.20 25 195 1.3E-17 T 23-04-2016 DC74_RS08670 d640f119763338c539fb502546e78428 442 SUPERFAMILY SSF53271 2 209 6.14E-54 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS08670 d640f119763338c539fb502546e78428 442 Pfam PF00156 Phosphoribosyl transferase domain 7 194 2.9E-21 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 DC74_RS08670 d640f119763338c539fb502546e78428 442 Gene3D G3DSA:3.40.50.2020 94 204 2.9E-38 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS08670 d640f119763338c539fb502546e78428 442 Gene3D G3DSA:3.40.50.2020 3 61 2.9E-38 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS08670 d640f119763338c539fb502546e78428 442 PANTHER PTHR31299 1 213 4.9E-82 T 23-04-2016 DC74_RS08670 d640f119763338c539fb502546e78428 442 Gene3D G3DSA:3.40.50.1820 233 437 1.1E-35 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08670 d640f119763338c539fb502546e78428 442 SUPERFAMILY SSF53474 234 437 1.43E-30 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS24425 7bf7ea24007f72f3b9bb1bcbb5be74ad 336 SUPERFAMILY SSF55846 18 196 2.16E-25 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS24425 7bf7ea24007f72f3b9bb1bcbb5be74ad 336 SUPERFAMILY SSF47090 252 327 8.63E-5 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS24425 7bf7ea24007f72f3b9bb1bcbb5be74ad 336 SMART SM00644 27 180 1.2E-20 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS24425 7bf7ea24007f72f3b9bb1bcbb5be74ad 336 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 39 179 3.4E-15 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS24425 7bf7ea24007f72f3b9bb1bcbb5be74ad 336 Gene3D G3DSA:3.40.80.10 23 195 1.2E-18 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS17340 b85ced59f637781a12f851ac3d754007 434 Gene3D G3DSA:3.50.50.60 242 321 9.6E-20 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17340 b85ced59f637781a12f851ac3d754007 434 Gene3D G3DSA:3.50.50.60 5 84 9.6E-20 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17340 b85ced59f637781a12f851ac3d754007 434 SUPERFAMILY SSF51905 136 322 2.31E-15 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17340 b85ced59f637781a12f851ac3d754007 434 SUPERFAMILY SSF51905 5 159 3.24E-18 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17340 b85ced59f637781a12f851ac3d754007 434 Gene3D G3DSA:3.50.50.60 85 241 4.5E-18 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17340 b85ced59f637781a12f851ac3d754007 434 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 308 4.2E-36 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17340 b85ced59f637781a12f851ac3d754007 434 PANTHER PTHR10632:SF8 4 99 8.4E-12 T 23-04-2016 DC74_RS17340 b85ced59f637781a12f851ac3d754007 434 PANTHER PTHR10632 4 99 8.4E-12 T 23-04-2016 DC74_RS08240 2b9fd5f290c09258aa221f65ccdba834 914 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 520 624 3.2E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS08240 2b9fd5f290c09258aa221f65ccdba834 914 SUPERFAMILY SSF55874 504 624 4.85E-17 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS08240 2b9fd5f290c09258aa221f65ccdba834 914 Gene3D G3DSA:3.30.565.10 483 626 1.7E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS08240 2b9fd5f290c09258aa221f65ccdba834 914 Pfam PF08376 Nitrate and nitrite sensing 58 292 2.6E-34 T 23-04-2016 IPR013587 Nitrate/nitrite sensing protein DC74_RS08240 2b9fd5f290c09258aa221f65ccdba834 914 PANTHER PTHR24423 780 887 1.1E-77 T 23-04-2016 DC74_RS08240 2b9fd5f290c09258aa221f65ccdba834 914 PANTHER PTHR24423 385 630 1.1E-77 T 23-04-2016 DC74_RS08240 2b9fd5f290c09258aa221f65ccdba834 914 PANTHER PTHR24423:SF523 780 887 1.1E-77 T 23-04-2016 DC74_RS08240 2b9fd5f290c09258aa221f65ccdba834 914 PANTHER PTHR24423:SF523 385 630 1.1E-77 T 23-04-2016 DC74_RS08240 2b9fd5f290c09258aa221f65ccdba834 914 Pfam PF00672 HAMP domain 317 401 1.3E-9 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS08240 2b9fd5f290c09258aa221f65ccdba834 914 SMART SM00387 517 627 1.1E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS04900 a93b89006b4002656cac9ecac81acc38 304 Pfam PF12833 Helix-turn-helix domain 226 304 1.4E-23 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS04900 a93b89006b4002656cac9ecac81acc38 304 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 256 301 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS04900 a93b89006b4002656cac9ecac81acc38 304 PANTHER PTHR11019 74 304 1.3E-31 T 23-04-2016 DC74_RS04900 a93b89006b4002656cac9ecac81acc38 304 Gene3D G3DSA:1.10.10.60 215 256 2.7E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04900 a93b89006b4002656cac9ecac81acc38 304 Gene3D G3DSA:1.10.10.60 257 304 1.2E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04900 a93b89006b4002656cac9ecac81acc38 304 SMART SM00342 220 304 1.4E-24 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS04900 a93b89006b4002656cac9ecac81acc38 304 Pfam PF14525 AraC-binding-like domain 17 191 4.1E-22 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS04900 a93b89006b4002656cac9ecac81acc38 304 PANTHER PTHR11019:SF50 74 304 1.3E-31 T 23-04-2016 DC74_RS04900 a93b89006b4002656cac9ecac81acc38 304 SUPERFAMILY SSF46689 255 304 6.72E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04900 a93b89006b4002656cac9ecac81acc38 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 274 289 2.9E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS04900 a93b89006b4002656cac9ecac81acc38 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 289 304 2.9E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 SUPERFAMILY SSF48264 22 432 1.7E-71 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 PANTHER PTHR11712 109 348 5.7E-53 T 23-04-2016 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 PANTHER PTHR11712 366 432 5.7E-53 T 23-04-2016 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 PRINTS PR00385 P450 superfamily signature 372 381 1.2E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 PRINTS PR00385 P450 superfamily signature 287 298 1.2E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 PRINTS PR00385 P450 superfamily signature 252 269 1.2E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 PRINTS PR00385 P450 superfamily signature 381 392 1.2E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 PRINTS PR00359 B-class P450 signature 333 348 5.1E-16 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 PRINTS PR00359 B-class P450 signature 148 164 5.1E-16 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 PRINTS PR00359 B-class P450 signature 305 332 5.1E-16 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 PRINTS PR00359 B-class P450 signature 287 298 5.1E-16 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 Gene3D G3DSA:1.10.630.10 19 432 2.4E-87 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 Pfam PF00067 Cytochrome P450 284 398 2.1E-24 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01410 0997dfd897a7df7e8578224b9ad92328 432 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 374 383 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS16725 1952844cd81218b450135ae40bb72cb3 446 SUPERFAMILY SSF161098 298 433 2.25E-44 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16725 1952844cd81218b450135ae40bb72cb3 446 SUPERFAMILY SSF161098 66 156 2.25E-44 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16725 1952844cd81218b450135ae40bb72cb3 446 PANTHER PTHR32243 309 446 7.7E-71 T 23-04-2016 DC74_RS16725 1952844cd81218b450135ae40bb72cb3 446 PANTHER PTHR32243 16 144 7.7E-71 T 23-04-2016 DC74_RS16725 1952844cd81218b450135ae40bb72cb3 446 PANTHER PTHR32243 170 175 7.7E-71 T 23-04-2016 DC74_RS16725 1952844cd81218b450135ae40bb72cb3 446 Gene3D G3DSA:1.10.3720.10 301 436 2.7E-68 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16725 1952844cd81218b450135ae40bb72cb3 446 Gene3D G3DSA:1.10.3720.10 23 149 2.7E-68 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16725 1952844cd81218b450135ae40bb72cb3 446 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 301 433 2.4E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16725 1952844cd81218b450135ae40bb72cb3 446 PANTHER PTHR32243:SF13 309 446 7.7E-71 T 23-04-2016 DC74_RS16725 1952844cd81218b450135ae40bb72cb3 446 PANTHER PTHR32243:SF13 16 144 7.7E-71 T 23-04-2016 DC74_RS16725 1952844cd81218b450135ae40bb72cb3 446 PANTHER PTHR32243:SF13 170 175 7.7E-71 T 23-04-2016 DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 Gene3D G3DSA:1.10.1040.10 175 270 2.4E-28 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 Gene3D G3DSA:1.10.1040.10 483 577 2.3E-31 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 Gene3D G3DSA:3.40.50.720 296 482 3.2E-51 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 Gene3D G3DSA:3.40.50.720 1 174 3.2E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 PANTHER PTHR23309:SF24 1 287 6.5E-251 T 23-04-2016 DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 PANTHER PTHR23309:SF24 458 580 6.5E-251 T 23-04-2016 DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 301 478 1.4E-56 T 23-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1 170 2.0E-54 T 23-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 SUPERFAMILY SSF48179 172 276 4.51E-27 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 481 577 1.5E-32 T 23-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 173 269 4.6E-28 T 23-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 SUPERFAMILY SSF51735 1 172 2.23E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 SUPERFAMILY SSF48179 481 578 9.35E-29 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 SUPERFAMILY SSF51735 297 478 7.73E-50 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 PANTHER PTHR23309 1 287 6.5E-251 T 23-04-2016 DC74_RS31785 b35ef81d5f14eca295d598e5d848ec48 580 PANTHER PTHR23309 458 580 6.5E-251 T 23-04-2016 DC74_RS37885 36f95518e7dc07f9ad8c3d386350ad53 135 Gene3D G3DSA:2.40.350.10 1 134 9.3E-39 T 23-04-2016 IPR023159 SO1590-like domain DC74_RS37885 36f95518e7dc07f9ad8c3d386350ad53 135 SUPERFAMILY SSF159238 2 133 1.7E-34 T 23-04-2016 IPR023159 SO1590-like domain DC74_RS37885 36f95518e7dc07f9ad8c3d386350ad53 135 Pfam PF11528 Protein of unknown function (DUF3224) 6 132 5.9E-34 T 23-04-2016 IPR021607 Protein of unknown function DUF3224 DC74_RS30310 bb863cf39e36e24136bd1433268164e4 115 SMART SM00347 3 97 9.6E-19 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS30310 bb863cf39e36e24136bd1433268164e4 115 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 1.3E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS30310 bb863cf39e36e24136bd1433268164e4 115 PRINTS PR00598 Bacterial regulatory protein MarR family signature 21 37 1.3E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS30310 bb863cf39e36e24136bd1433268164e4 115 PRINTS PR00598 Bacterial regulatory protein MarR family signature 38 53 1.3E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS30310 bb863cf39e36e24136bd1433268164e4 115 Gene3D G3DSA:1.10.10.10 3 107 2.4E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS30310 bb863cf39e36e24136bd1433268164e4 115 SUPERFAMILY SSF46785 3 108 3.03E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS30310 bb863cf39e36e24136bd1433268164e4 115 Pfam PF01047 MarR family 4 61 3.2E-15 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS30310 bb863cf39e36e24136bd1433268164e4 115 PANTHER PTHR33164 3 107 6.1E-23 T 23-04-2016 DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 PANTHER PTHR26402 2 201 2.1E-101 T 23-04-2016 DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 3.8E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 3.8E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 3.8E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 2.0E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 SUPERFAMILY SSF46894 127 201 9.18E-19 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 PANTHER PTHR26402:SF137 2 201 2.1E-101 T 23-04-2016 DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 SMART SM00448 2 115 1.0E-23 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 Gene3D G3DSA:3.40.50.2300 2 143 5.9E-33 T 23-04-2016 DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 Pfam PF00072 Response regulator receiver domain 5 116 6.6E-22 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 155 182 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 SUPERFAMILY SSF52172 2 128 3.98E-28 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 Gene3D G3DSA:1.10.10.10 144 201 2.7E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13585 7418a6260be808d6f6f3e6a4e635c381 201 SMART SM00421 138 195 1.9E-20 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12330 42c0c1cfc81bb15588c8011c0fabc537 126 SUPERFAMILY SSF141734 14 119 8.89E-47 T 23-04-2016 DC74_RS12330 42c0c1cfc81bb15588c8011c0fabc537 126 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 64 118 5.0E-24 T 23-04-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 DC74_RS12330 42c0c1cfc81bb15588c8011c0fabc537 126 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 15 118 31.687 T 23-04-2016 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 DC74_RS12330 42c0c1cfc81bb15588c8011c0fabc537 126 PANTHER PTHR21256 14 117 1.6E-59 T 23-04-2016 DC74_RS12330 42c0c1cfc81bb15588c8011c0fabc537 126 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 41 113 3.2E-33 T 23-04-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 DC74_RS28655 629a646303c4d05817dd1f8b99f8692d 219 SMART SM00448 5 119 7.4E-31 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS28655 629a646303c4d05817dd1f8b99f8692d 219 SUPERFAMILY SSF52172 3 146 1.57E-37 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS28655 629a646303c4d05817dd1f8b99f8692d 219 PANTHER PTHR26402:SF563 5 129 2.2E-54 T 23-04-2016 DC74_RS28655 629a646303c4d05817dd1f8b99f8692d 219 Gene3D G3DSA:3.40.50.2300 3 126 8.1E-36 T 23-04-2016 DC74_RS28655 629a646303c4d05817dd1f8b99f8692d 219 PANTHER PTHR26402 5 129 2.2E-54 T 23-04-2016 DC74_RS28655 629a646303c4d05817dd1f8b99f8692d 219 Pfam PF00072 Response regulator receiver domain 7 119 1.4E-24 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 Gene3D G3DSA:1.10.1660.10 10 112 2.1E-25 T 23-04-2016 DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 345 518 3.2E-25 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 Pfam PF00376 MerR family regulatory protein 10 47 7.8E-14 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 SUPERFAMILY SSF109854 333 466 7.63E-19 T 23-04-2016 DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 SUPERFAMILY SSF46955 9 111 5.86E-22 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 45 65 4.7E-6 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 21 34 4.7E-6 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 10 21 4.7E-6 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 Gene3D G3DSA:1.20.120.450 334 395 3.8E-7 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 345 518 9.0E-40 T 23-04-2016 IPR017520 Conserved hypothetical protein CHP03086 DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 345 460 2.8E-14 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 SMART SM00422 9 78 4.6E-21 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS11370 37f92792b09f9ac2582974ccf54ae431 520 PANTHER PTHR30204 1 141 8.8E-19 T 23-04-2016 DC74_RS09790 86aad51ae4f8b8402eeff7dc7326fb87 271 Pfam PF00588 SpoU rRNA Methylase family 121 263 2.4E-31 T 23-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 DC74_RS09790 86aad51ae4f8b8402eeff7dc7326fb87 271 Gene3D G3DSA:3.40.1280.10 117 267 4.3E-50 T 23-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DC74_RS09790 86aad51ae4f8b8402eeff7dc7326fb87 271 PANTHER PTHR12029 1 266 1.8E-138 T 23-04-2016 DC74_RS09790 86aad51ae4f8b8402eeff7dc7326fb87 271 Gene3D G3DSA:3.30.1330.30 7 105 8.6E-16 T 23-04-2016 IPR029064 50S ribosomal protein L30e-like DC74_RS09790 86aad51ae4f8b8402eeff7dc7326fb87 271 SUPERFAMILY SSF75217 116 267 2.03E-37 T 23-04-2016 IPR029028 Alpha/beta knot methyltransferases DC74_RS09790 86aad51ae4f8b8402eeff7dc7326fb87 271 SUPERFAMILY SSF55315 6 106 2.59E-16 T 23-04-2016 IPR029064 50S ribosomal protein L30e-like DC74_RS09790 86aad51ae4f8b8402eeff7dc7326fb87 271 PANTHER PTHR12029:SF52 1 266 1.8E-138 T 23-04-2016 DC74_RS33705 8f23ac01f04fb66af4ac174a5577b6a2 320 PANTHER PTHR30468:SF6 17 319 3.6E-84 T 23-04-2016 DC74_RS33705 8f23ac01f04fb66af4ac174a5577b6a2 320 SUPERFAMILY SSF53335 27 192 2.45E-13 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS33705 8f23ac01f04fb66af4ac174a5577b6a2 320 SUPERFAMILY SSF53335 282 314 2.45E-13 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS33705 8f23ac01f04fb66af4ac174a5577b6a2 320 PANTHER PTHR30468 17 319 3.6E-84 T 23-04-2016 DC74_RS33705 8f23ac01f04fb66af4ac174a5577b6a2 320 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 6 319 54.479 T 23-04-2016 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550|UniPathway: UPA01014 DC74_RS33705 8f23ac01f04fb66af4ac174a5577b6a2 320 PIRSF PIRSF018005 4 320 6.8E-134 T 23-04-2016 IPR017804 Methyltransferase EgtD-like DC74_RS33705 8f23ac01f04fb66af4ac174a5577b6a2 320 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 190 314 1.4E-40 T 23-04-2016 IPR019257 Histidine-specific methyltransferase, SAM-dependent DC74_RS33705 8f23ac01f04fb66af4ac174a5577b6a2 320 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 19 316 6.0E-114 T 23-04-2016 IPR017804 Methyltransferase EgtD-like DC74_RS33705 8f23ac01f04fb66af4ac174a5577b6a2 320 Gene3D G3DSA:3.40.50.150 40 212 6.3E-8 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS33705 8f23ac01f04fb66af4ac174a5577b6a2 320 Gene3D G3DSA:3.40.50.150 279 307 6.3E-8 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 SMART SM00998 369 455 1.1E-19 T 23-04-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 11 454 1.8E-124 T 23-04-2016 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 SUPERFAMILY SSF48557 10 456 2.83E-78 T 23-04-2016 IPR008948 L-Aspartase-like GO:0003824 DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 Gene3D G3DSA:1.10.275.10 13 101 5.6E-23 T 23-04-2016 IPR024083 Fumarase/histidase, N-terminal DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 PANTHER PTHR11444 11 466 1.0E-113 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 Gene3D G3DSA:1.20.200.10 102 452 1.9E-79 T 23-04-2016 DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 PANTHER PTHR11444:SF2 11 466 1.0E-113 T 23-04-2016 DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 Pfam PF00206 Lyase 53 300 1.9E-18 T 23-04-2016 IPR022761 Fumarate lyase, N-terminal DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 Pfam PF10397 Adenylosuccinate lyase C-terminus 370 453 7.3E-12 T 23-04-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 23-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 PRINTS PR00149 Fumarate lyase superfamily signature 98 116 4.0E-11 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 4.0E-11 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 4.0E-11 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS35295 7b3c306d67237b0782ef0b8621a36354 477 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 4.0E-11 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 255 267 - T 23-04-2016 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 6 470 8.2E-202 T 23-04-2016 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 Gene3D G3DSA:1.10.1040.10 182 436 5.1E-99 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 175 2.9E-50 T 23-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 PANTHER PTHR11811:SF25 1 474 3.7E-259 T 23-04-2016 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 Gene3D G3DSA:3.40.50.720 4 181 1.8E-57 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 PANTHER PTHR11811 1 474 3.7E-259 T 23-04-2016 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 251 278 6.4E-80 T 23-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 359 381 6.4E-80 T 23-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 5 28 6.4E-80 T 23-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 68 97 6.4E-80 T 23-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 121 146 6.4E-80 T 23-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 169 197 6.4E-80 T 23-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 SUPERFAMILY SSF48179 178 472 8.5E-114 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 PIRSF PIRSF000109 1 477 6.5E-195 T 23-04-2016 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 180 469 7.4E-117 T 23-04-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 SMART SM01350 180 470 1.3E-183 T 23-04-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 Gene3D G3DSA:1.20.5.320 439 474 2.0E-19 T 23-04-2016 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS02105 8f4d9bcb3783a3e38bca74f0e899865c 484 SUPERFAMILY SSF51735 5 178 3.29E-51 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20905 684429ca1f297a1b7208f7e99583f002 160 Gene3D G3DSA:1.10.10.10 22 142 4.4E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20905 684429ca1f297a1b7208f7e99583f002 160 PANTHER PTHR33164 23 137 8.9E-49 T 23-04-2016 DC74_RS20905 684429ca1f297a1b7208f7e99583f002 160 PANTHER PTHR33164:SF15 23 137 8.9E-49 T 23-04-2016 DC74_RS20905 684429ca1f297a1b7208f7e99583f002 160 SMART SM00347 40 142 6.7E-13 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS20905 684429ca1f297a1b7208f7e99583f002 160 SUPERFAMILY SSF46785 23 139 2.73E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20905 684429ca1f297a1b7208f7e99583f002 160 Pfam PF01047 MarR family 48 109 1.1E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS00425 bf5f5d23de9f6389f55fbf4db573d0fa 114 PIRSF PIRSF000077 4 111 7.8E-25 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DC74_RS00425 bf5f5d23de9f6389f55fbf4db573d0fa 114 Gene3D G3DSA:3.40.30.10 4 110 1.4E-26 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS00425 bf5f5d23de9f6389f55fbf4db573d0fa 114 Pfam PF00085 Thioredoxin 7 110 4.8E-20 T 23-04-2016 IPR013766 Thioredoxin domain GO:0045454 DC74_RS00425 bf5f5d23de9f6389f55fbf4db573d0fa 114 SUPERFAMILY SSF52833 5 110 5.89E-26 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS00425 bf5f5d23de9f6389f55fbf4db573d0fa 114 PANTHER PTHR10438 10 109 5.7E-21 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DC74_RS08495 a3bf6d266102f80d9cc32ac15d411b79 807 PANTHER PTHR31273 23 807 0.0 T 23-04-2016 DC74_RS08495 a3bf6d266102f80d9cc32ac15d411b79 807 Gene3D G3DSA:3.40.50.970 70 276 3.7E-21 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS08495 a3bf6d266102f80d9cc32ac15d411b79 807 ProSitePatterns PS60002 Phosphoketolase signature 1. 160 166 - T 23-04-2016 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 DC74_RS08495 a3bf6d266102f80d9cc32ac15d411b79 807 SUPERFAMILY SSF52518 413 604 1.24E-22 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS08495 a3bf6d266102f80d9cc32ac15d411b79 807 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 415 591 1.5E-86 T 23-04-2016 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 DC74_RS08495 a3bf6d266102f80d9cc32ac15d411b79 807 PANTHER PTHR31273:SF0 23 807 0.0 T 23-04-2016 DC74_RS08495 a3bf6d266102f80d9cc32ac15d411b79 807 Pfam PF09363 XFP C-terminal domain 602 804 2.5E-84 T 23-04-2016 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 DC74_RS08495 a3bf6d266102f80d9cc32ac15d411b79 807 PIRSF PIRSF017245 2 806 0.0 T 23-04-2016 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 DC74_RS08495 a3bf6d266102f80d9cc32ac15d411b79 807 Pfam PF09364 XFP N-terminal domain 25 400 1.6E-177 T 23-04-2016 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal DC74_RS08495 a3bf6d266102f80d9cc32ac15d411b79 807 SUPERFAMILY SSF52518 23 385 3.93E-69 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS08495 a3bf6d266102f80d9cc32ac15d411b79 807 ProSitePatterns PS60003 Phosphoketolase signature 2. 173 191 - T 23-04-2016 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 DC74_RS08495 a3bf6d266102f80d9cc32ac15d411b79 807 Hamap MF_01403 Probable phosphoketolase. 21 806 40.537 T 23-04-2016 IPR023962 Probable phosphoketolase DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 Gene3D G3DSA:3.50.50.60 155 227 7.1E-14 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 260 278 1.1E-7 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 96 104 1.1E-7 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 1.1E-7 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.1E-7 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 272 2.4E-12 T 23-04-2016 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 2.4E-12 T 23-04-2016 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.4E-12 T 23-04-2016 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 2.4E-12 T 23-04-2016 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 PANTHER PTHR22912:SF180 4 272 1.7E-16 T 23-04-2016 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 286 7.9E-39 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 Gene3D G3DSA:3.50.50.60 105 154 1.7E-5 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 Gene3D G3DSA:3.50.50.60 232 304 1.9E-30 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 Gene3D G3DSA:3.50.50.60 5 104 1.9E-30 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 SUPERFAMILY SSF51905 6 302 3.35E-30 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS23035 e39e8ac63c1808353dcaf83352754485 407 PANTHER PTHR22912 4 272 1.7E-16 T 23-04-2016 DC74_RS35760 5278fc3c6bef8b259abcd9ea290a4be2 232 Gene3D G3DSA:1.10.10.10 132 225 5.4E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35760 5278fc3c6bef8b259abcd9ea290a4be2 232 SUPERFAMILY SSF52172 3 177 6.26E-41 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS35760 5278fc3c6bef8b259abcd9ea290a4be2 232 PANTHER PTHR26402:SF292 2 223 1.5E-65 T 23-04-2016 DC74_RS35760 5278fc3c6bef8b259abcd9ea290a4be2 232 Gene3D G3DSA:3.40.50.2300 3 120 3.4E-39 T 23-04-2016 DC74_RS35760 5278fc3c6bef8b259abcd9ea290a4be2 232 PANTHER PTHR26402 2 223 1.5E-65 T 23-04-2016 DC74_RS35760 5278fc3c6bef8b259abcd9ea290a4be2 232 SMART SM00862 146 224 2.8E-17 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS35760 5278fc3c6bef8b259abcd9ea290a4be2 232 Pfam PF00072 Response regulator receiver domain 4 113 2.5E-27 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS35760 5278fc3c6bef8b259abcd9ea290a4be2 232 SMART SM00448 2 112 8.5E-41 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS35760 5278fc3c6bef8b259abcd9ea290a4be2 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 6.8E-19 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS18580 703d8a6c4d6718be3d477cb1513d5d95 147 SUPERFAMILY SSF52161 4 144 2.35E-60 T 23-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 DC74_RS18580 703d8a6c4d6718be3d477cb1513d5d95 147 Pfam PF00572 Ribosomal protein L13 14 137 1.4E-56 T 23-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 DC74_RS18580 703d8a6c4d6718be3d477cb1513d5d95 147 PANTHER PTHR11545 2 144 2.9E-75 T 23-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 DC74_RS18580 703d8a6c4d6718be3d477cb1513d5d95 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 146 28.444 T 23-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 DC74_RS18580 703d8a6c4d6718be3d477cb1513d5d95 147 PIRSF PIRSF002181 2 147 1.5E-47 T 23-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 DC74_RS18580 703d8a6c4d6718be3d477cb1513d5d95 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 1.4E-60 T 23-04-2016 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 DC74_RS18580 703d8a6c4d6718be3d477cb1513d5d95 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 23-04-2016 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 DC74_RS18580 703d8a6c4d6718be3d477cb1513d5d95 147 Gene3D G3DSA:3.90.1180.10 3 141 1.7E-63 T 23-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 PANTHER PTHR21327 16 419 2.8E-240 T 23-04-2016 DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 SUPERFAMILY SSF142695 222 393 2.09E-67 T 23-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 Gene3D G3DSA:3.90.870.10 16 227 3.8E-94 T 23-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 227 414 5.4E-72 T 23-04-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 17 413 53.443 T 23-04-2016 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275|UniPathway: UPA00275 DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 PIRSF PIRSF001259 16 419 9.3E-174 T 23-04-2016 DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 19 216 1.2E-71 T 23-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 16 220 38.043 T 23-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 221 417 40.334 T 23-04-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 SUPERFAMILY SSF55821 17 218 5.95E-81 T 23-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 22 215 2.1E-82 T 23-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 PANTHER PTHR21327:SF6 16 419 2.8E-240 T 23-04-2016 DC74_RS09215 1fd92cc98e7cb9cd2a5ec6130e4ec3c1 428 Pfam PF00925 GTP cyclohydrolase II 225 390 1.3E-70 T 23-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 DC74_RS15495 11a317bcd86b63b172ffe6ac0cff34a4 443 Pfam PF01547 Bacterial extracellular solute-binding protein 49 348 1.3E-33 T 23-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 DC74_RS15495 11a317bcd86b63b172ffe6ac0cff34a4 443 Gene3D G3DSA:3.40.190.10 155 334 2.5E-28 T 23-04-2016 DC74_RS15495 11a317bcd86b63b172ffe6ac0cff34a4 443 SUPERFAMILY SSF53850 37 419 5.0E-62 T 23-04-2016 DC74_RS15495 11a317bcd86b63b172ffe6ac0cff34a4 443 Gene3D G3DSA:3.40.190.10 38 154 3.8E-39 T 23-04-2016 DC74_RS15495 11a317bcd86b63b172ffe6ac0cff34a4 443 Gene3D G3DSA:3.40.190.10 335 387 3.8E-39 T 23-04-2016 DC74_RS15495 11a317bcd86b63b172ffe6ac0cff34a4 443 PANTHER PTHR30061 1 435 2.0E-68 T 23-04-2016 DC74_RS15495 11a317bcd86b63b172ffe6ac0cff34a4 443 PANTHER PTHR30061:SF1 1 435 2.0E-68 T 23-04-2016 DC74_RS35395 d8913502540cbcd569cb49e9554fba12 434 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 252 289 - T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS35395 d8913502540cbcd569cb49e9554fba12 434 PANTHER PTHR11986 5 433 2.1E-186 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS35395 d8913502540cbcd569cb49e9554fba12 434 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 6 434 49.167 T 23-04-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62|UniPathway: UPA00078 DC74_RS35395 d8913502540cbcd569cb49e9554fba12 434 Gene3D G3DSA:3.40.640.10 71 337 2.1E-85 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS35395 d8913502540cbcd569cb49e9554fba12 434 SUPERFAMILY SSF53383 9 432 1.33E-115 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS35395 d8913502540cbcd569cb49e9554fba12 434 Pfam PF00202 Aminotransferase class-III 51 429 1.6E-116 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS35395 d8913502540cbcd569cb49e9554fba12 434 PANTHER PTHR11986:SF8 5 433 2.1E-186 T 23-04-2016 DC74_RS35395 d8913502540cbcd569cb49e9554fba12 434 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 18 430 9.5E-166 T 23-04-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62|UniPathway: UPA00078 DC74_RS35395 d8913502540cbcd569cb49e9554fba12 434 Gene3D G3DSA:3.90.1150.10 342 433 4.3E-50 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS35395 d8913502540cbcd569cb49e9554fba12 434 Gene3D G3DSA:3.90.1150.10 9 70 4.3E-50 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 SUPERFAMILY SSF55785 10 134 2.07E-8 T 23-04-2016 IPR000014 PAS domain DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 SUPERFAMILY SSF47384 141 219 4.51E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 Gene3D G3DSA:3.30.450.20 13 121 1.1E-9 T 23-04-2016 DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 SUPERFAMILY SSF55874 215 379 3.54E-43 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 Gene3D G3DSA:3.30.565.10 210 380 1.9E-43 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 218 1.1E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 SMART SM00387 269 381 5.2E-34 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 269 380 1.2E-23 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 PANTHER PTHR24423 8 389 5.1E-90 T 23-04-2016 DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 SMART SM00388 156 224 1.8E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 359 1.1E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 320 1.1E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 334 1.1E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 378 1.1E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 Pfam PF08448 PAS fold 25 138 4.0E-9 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 Gene3D G3DSA:1.10.287.130 161 209 5.7E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS35765 b98b1b2dd2c5de19b014ad65096ff08d 394 Gene3D G3DSA:3.30.450.20 122 160 3.0E-8 T 23-04-2016 DC74_RS06060 b5e8de4e1cd742a6c7e5a03928aec7e1 220 PANTHER PTHR26402:SF553 1 217 1.3E-81 T 23-04-2016 DC74_RS06060 b5e8de4e1cd742a6c7e5a03928aec7e1 220 PANTHER PTHR26402 1 217 1.3E-81 T 23-04-2016 DC74_RS06060 b5e8de4e1cd742a6c7e5a03928aec7e1 220 Gene3D G3DSA:1.10.10.10 124 217 3.2E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06060 b5e8de4e1cd742a6c7e5a03928aec7e1 220 Gene3D G3DSA:3.40.50.2300 1 120 2.2E-34 T 23-04-2016 DC74_RS06060 b5e8de4e1cd742a6c7e5a03928aec7e1 220 SMART SM00862 145 217 6.8E-17 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS06060 b5e8de4e1cd742a6c7e5a03928aec7e1 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 1.8E-16 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS06060 b5e8de4e1cd742a6c7e5a03928aec7e1 220 SUPERFAMILY SSF52172 1 174 3.13E-37 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS06060 b5e8de4e1cd742a6c7e5a03928aec7e1 220 Pfam PF00072 Response regulator receiver domain 3 112 9.5E-24 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS06060 b5e8de4e1cd742a6c7e5a03928aec7e1 220 SMART SM00448 1 112 1.4E-31 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS32910 936c37d0bcc644a9e2ae9607be371d14 541 PANTHER PTHR34473:SF1 28 535 8.2E-58 T 23-04-2016 DC74_RS32910 936c37d0bcc644a9e2ae9607be371d14 541 Pfam PF03703 Bacterial PH domain 282 333 3.2E-4 T 23-04-2016 IPR005182 Domain of unknown function DUF304 DC74_RS32910 936c37d0bcc644a9e2ae9607be371d14 541 Pfam PF03703 Bacterial PH domain 93 171 2.2E-12 T 23-04-2016 IPR005182 Domain of unknown function DUF304 DC74_RS32910 936c37d0bcc644a9e2ae9607be371d14 541 Pfam PF03703 Bacterial PH domain 441 507 7.7E-7 T 23-04-2016 IPR005182 Domain of unknown function DUF304 DC74_RS32910 936c37d0bcc644a9e2ae9607be371d14 541 PIRSF PIRSF026631 35 520 2.6E-61 T 23-04-2016 IPR014529 Uncharacterised conserved protein UCP026631 DC74_RS32910 936c37d0bcc644a9e2ae9607be371d14 541 PANTHER PTHR34473 28 535 8.2E-58 T 23-04-2016 DC74_RS08970 201f26c99b395b25a2adeaca15e07bd8 177 Pfam PF13673 Acetyltransferase (GNAT) domain 49 148 1.1E-11 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS08970 201f26c99b395b25a2adeaca15e07bd8 177 Gene3D G3DSA:3.40.630.30 6 157 2.1E-28 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS08970 201f26c99b395b25a2adeaca15e07bd8 177 SUPERFAMILY SSF55729 1 156 1.08E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS08970 201f26c99b395b25a2adeaca15e07bd8 177 PANTHER PTHR23091:SF184 1 176 4.5E-79 T 23-04-2016 DC74_RS08970 201f26c99b395b25a2adeaca15e07bd8 177 PANTHER PTHR23091 1 176 4.5E-79 T 23-04-2016 DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 172 185 - T 23-04-2016 IPR018181 Heat shock protein 70, conserved site DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 23-04-2016 IPR018181 Heat shock protein 70, conserved site DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 SUPERFAMILY SSF100920 360 516 5.62E-59 T 23-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 Gene3D G3DSA:3.30.420.40 4 38 5.5E-56 T 23-04-2016 DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 Gene3D G3DSA:3.30.420.40 106 170 5.5E-56 T 23-04-2016 DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 Pfam PF00012 Hsp70 protein 4 579 1.7E-242 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 Gene3D G3DSA:3.30.30.30 39 105 2.6E-13 T 23-04-2016 DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 313 327 - T 23-04-2016 IPR018181 Heat shock protein 70, conserved site DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 SUPERFAMILY SSF53067 3 164 2.78E-55 T 23-04-2016 DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 PANTHER PTHR19375:SF173 2 618 0.0 T 23-04-2016 DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 PANTHER PTHR19375 2 618 0.0 T 23-04-2016 DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 Gene3D G3DSA:3.30.420.40 295 337 7.1E-35 T 23-04-2016 DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 Gene3D G3DSA:3.30.420.40 171 205 7.1E-35 T 23-04-2016 DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 PRINTS PR00301 70kDa heat shock protein signature 310 326 2.3E-73 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 PRINTS PR00301 70kDa heat shock protein signature 341 361 2.3E-73 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 PRINTS PR00301 70kDa heat shock protein signature 178 188 2.3E-73 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.3E-73 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 PRINTS PR00301 70kDa heat shock protein signature 119 139 2.3E-73 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.3E-73 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.3E-73 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 PRINTS PR00301 70kDa heat shock protein signature 445 461 2.3E-73 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 PRINTS PR00301 70kDa heat shock protein signature 364 383 2.3E-73 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 Gene3D G3DSA:1.20.1270.10 509 579 1.5E-26 T 23-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 579 7.8E-277 T 23-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 Gene3D G3DSA:3.90.640.10 206 291 4.3E-31 T 23-04-2016 DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 Gene3D G3DSA:2.60.34.10 366 508 4.2E-72 T 23-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 SUPERFAMILY SSF53067 167 358 1.77E-66 T 23-04-2016 DC74_RS37750 4a307ff32a39e987e3e417e3e8f9ee5c 622 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 614 35.849 T 23-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 Pfam PF00005 ABC transporter 405 554 1.0E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 PANTHER PTHR24221 107 633 0.0 T 23-04-2016 DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 PANTHER PTHR24221 6 69 0.0 T 23-04-2016 DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 ProSitePatterns PS00211 ABC transporters family signature. 526 540 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 PANTHER PTHR24221:SF271 107 633 0.0 T 23-04-2016 DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 PANTHER PTHR24221:SF271 6 69 0.0 T 23-04-2016 DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 Gene3D G3DSA:3.40.50.300 388 618 2.7E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 Pfam PF00664 ABC transporter transmembrane region 32 342 5.1E-61 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 SUPERFAMILY SSF52540 380 625 2.98E-89 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 SMART SM00382 413 600 3.8E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 SUPERFAMILY SSF90123 102 375 1.57E-86 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 SUPERFAMILY SSF90123 17 61 1.57E-86 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 Gene3D G3DSA:1.20.1560.10 17 61 6.1E-90 T 23-04-2016 DC74_RS23195 0a82643ec773c585deff2a65996f781a 633 Gene3D G3DSA:1.20.1560.10 93 373 6.1E-90 T 23-04-2016 DC74_RS37415 29968bbd4fb9369354dec3a98dcd6ff8 251 Gene3D G3DSA:3.40.50.1820 43 229 2.7E-17 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS37415 29968bbd4fb9369354dec3a98dcd6ff8 251 SUPERFAMILY SSF53474 40 226 8.7E-13 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS37415 29968bbd4fb9369354dec3a98dcd6ff8 251 SMART SM01110 30 240 4.0E-4 T 23-04-2016 IPR000675 Cutinase/acetylxylan esterase GO:0008152|GO:0016787 DC74_RS37415 29968bbd4fb9369354dec3a98dcd6ff8 251 Pfam PF08237 PE-PPE domain 73 197 5.7E-15 T 23-04-2016 IPR013228 PE-PPE, C-terminal DC74_RS31505 8c976fd3bed16d314f75d7edb5666ebd 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 63 340 6.4E-56 T 23-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 DC74_RS31505 8c976fd3bed16d314f75d7edb5666ebd 355 PANTHER PTHR32196:SF22 4 352 1.6E-101 T 23-04-2016 DC74_RS31505 8c976fd3bed16d314f75d7edb5666ebd 355 PANTHER PTHR32196 4 352 1.6E-101 T 23-04-2016 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 SUPERFAMILY SSF56672 500 901 8.89E-139 T 23-04-2016 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 PANTHER PTHR10133:SF27 1 902 0.0 T 23-04-2016 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 Gene3D G3DSA:3.40.50.1010 15 198 1.9E-68 T 23-04-2016 IPR029060 PIN domain-like DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 Gene3D G3DSA:1.20.1060.10 519 637 2.9E-32 T 23-04-2016 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 Gene3D G3DSA:1.10.150.20 687 793 5.0E-33 T 23-04-2016 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 PANTHER PTHR10133 1 902 0.0 T 23-04-2016 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 Gene3D G3DSA:1.10.150.20 199 258 1.1E-24 T 23-04-2016 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 SUPERFAMILY SSF53098 325 494 1.21E-26 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 SUPERFAMILY SSF88723 11 183 3.18E-54 T 23-04-2016 IPR029060 PIN domain-like DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 15 183 3.6E-55 T 23-04-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 SMART SM00475 12 274 1.2E-144 T 23-04-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 766 777 6.2E-76 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 652 667 6.2E-76 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 850 863 6.2E-76 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 629 651 6.2E-76 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 820 836 6.2E-76 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 705 718 6.2E-76 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 788 799 6.2E-76 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 729 754 6.2E-76 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 PRINTS PR00868 DNA-polymerase family A (pol I) signature 675 698 6.2E-76 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 SUPERFAMILY SSF47807 184 292 2.09E-28 T 23-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 Gene3D G3DSA:3.30.70.370 638 686 4.0E-64 T 23-04-2016 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 Gene3D G3DSA:3.30.70.370 794 902 4.0E-64 T 23-04-2016 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 SMART SM00279 186 221 4.8E-14 T 23-04-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 SMART SM00482 660 867 2.1E-114 T 23-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 185 278 1.6E-26 T 23-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 Pfam PF00476 DNA polymerase family A 527 900 2.1E-142 T 23-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 TIGRFAM TIGR00593 pola: DNA polymerase I 16 902 3.7E-292 T 23-04-2016 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS12075 d5886d85f52d8399273760be7a8b6f44 904 Gene3D G3DSA:3.30.420.10 325 517 4.1E-47 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS37940 dec72504203bd9f313c03ddb50fbe67a 152 Gene3D G3DSA:3.30.530.20 15 149 8.9E-24 T 23-04-2016 IPR023393 START-like domain DC74_RS37940 dec72504203bd9f313c03ddb50fbe67a 152 SUPERFAMILY SSF55961 17 148 1.21E-27 T 23-04-2016 DC74_RS37940 dec72504203bd9f313c03ddb50fbe67a 152 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 27 147 2.6E-21 T 23-04-2016 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 DC74_RS31485 8da10938bafb1f89014173e084679024 202 Gene3D G3DSA:1.20.1250.20 6 170 5.3E-8 T 23-04-2016 DC74_RS31485 8da10938bafb1f89014173e084679024 202 SUPERFAMILY SSF103473 3 175 1.11E-14 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS24125 5fbba8eebde2a37e5e823c913560b3eb 183 Gene3D G3DSA:1.10.357.10 1 156 2.2E-19 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS24125 5fbba8eebde2a37e5e823c913560b3eb 183 SUPERFAMILY SSF46689 1 37 5.64E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS24125 5fbba8eebde2a37e5e823c913560b3eb 183 PANTHER PTHR30328 1 158 2.7E-21 T 23-04-2016 DC74_RS24125 5fbba8eebde2a37e5e823c913560b3eb 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 29 1.4E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS24125 5fbba8eebde2a37e5e823c913560b3eb 183 PANTHER PTHR30328:SF29 1 158 2.7E-21 T 23-04-2016 DC74_RS24125 5fbba8eebde2a37e5e823c913560b3eb 183 SUPERFAMILY SSF48498 46 171 1.52E-23 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS16730 93e99ddbff70cd6fc0522ac3bb112a44 280 Gene3D G3DSA:1.10.3720.10 12 268 2.6E-57 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16730 93e99ddbff70cd6fc0522ac3bb112a44 280 PANTHER PTHR32243:SF9 1 280 1.5E-133 T 23-04-2016 DC74_RS16730 93e99ddbff70cd6fc0522ac3bb112a44 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 265 4.1E-11 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16730 93e99ddbff70cd6fc0522ac3bb112a44 280 PANTHER PTHR32243 1 280 1.5E-133 T 23-04-2016 DC74_RS16730 93e99ddbff70cd6fc0522ac3bb112a44 280 SUPERFAMILY SSF161098 13 280 4.77E-65 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 SMART SM00866 90 230 5.2E-7 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 Gene3D G3DSA:1.10.10.10 1 60 4.6E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 PANTHER PTHR11751:SF432 119 144 2.9E-17 T 23-04-2016 DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 Pfam PF07702 UTRA domain 98 219 2.4E-17 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 SMART SM00345 5 64 7.5E-16 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 PANTHER PTHR11751 2 67 2.9E-17 T 23-04-2016 DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 PANTHER PTHR11751 119 144 2.9E-17 T 23-04-2016 DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 Gene3D G3DSA:3.40.1410.10 61 223 2.3E-25 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 9.6E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 9.6E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 PANTHER PTHR11751:SF432 2 67 2.9E-17 T 23-04-2016 DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 1 64 1.2E-18 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 SUPERFAMILY SSF64288 52 221 2.36E-26 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS40160 b769b6e8eed518dc3bc2d32ac9bdcb4c 241 SUPERFAMILY SSF46785 1 67 9.62E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26345 2c29876891db1fdeccbdbafeaba88d14 450 Gene3D G3DSA:3.65.10.10 30 254 3.9E-61 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 DC74_RS26345 2c29876891db1fdeccbdbafeaba88d14 450 Gene3D G3DSA:3.65.10.10 255 439 7.2E-54 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 DC74_RS26345 2c29876891db1fdeccbdbafeaba88d14 450 PANTHER PTHR21090 19 440 2.6E-148 T 23-04-2016 DC74_RS26345 2c29876891db1fdeccbdbafeaba88d14 450 PANTHER PTHR21090:SF5 19 440 2.6E-148 T 23-04-2016 DC74_RS26345 2c29876891db1fdeccbdbafeaba88d14 450 PIRSF PIRSF000505 9 444 1.9E-110 T 23-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS26345 2c29876891db1fdeccbdbafeaba88d14 450 SUPERFAMILY SSF55205 18 438 1.05E-100 T 23-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 DC74_RS26345 2c29876891db1fdeccbdbafeaba88d14 450 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 23 439 1.7E-110 T 23-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS26345 2c29876891db1fdeccbdbafeaba88d14 450 ProSitePatterns PS00104 EPSP synthase signature 1. 102 116 - T 23-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS26345 2c29876891db1fdeccbdbafeaba88d14 450 ProSitePatterns PS00885 EPSP synthase signature 2. 355 373 - T 23-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS26345 2c29876891db1fdeccbdbafeaba88d14 450 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 17 433 1.5E-105 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 DC74_RS26345 2c29876891db1fdeccbdbafeaba88d14 450 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 18 442 28.685 T 23-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS26025 16c027650c4820ea30bb38ec7dce82e4 378 Gene3D G3DSA:3.30.460.20 31 171 9.1E-47 T 23-04-2016 DC74_RS26025 16c027650c4820ea30bb38ec7dce82e4 378 Pfam PF01544 CorA-like Mg2+ transporter protein 63 368 3.0E-61 T 23-04-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 DC74_RS26025 16c027650c4820ea30bb38ec7dce82e4 378 SUPERFAMILY SSF144083 314 375 9.15E-21 T 23-04-2016 DC74_RS26025 16c027650c4820ea30bb38ec7dce82e4 378 Gene3D G3DSA:1.20.58.340 302 378 6.7E-28 T 23-04-2016 DC74_RS26025 16c027650c4820ea30bb38ec7dce82e4 378 SUPERFAMILY SSF143865 33 309 4.71E-65 T 23-04-2016 DC74_RS26025 16c027650c4820ea30bb38ec7dce82e4 378 PANTHER PTHR21535 54 378 1.1E-62 T 23-04-2016 DC74_RS26025 16c027650c4820ea30bb38ec7dce82e4 378 Gene3D G3DSA:1.20.58.340 172 300 4.2E-36 T 23-04-2016 DC74_RS11035 3ef7a489bf713acf341ca0e9cc7eeaf5 201 SUPERFAMILY SSF46785 6 81 8.16E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11035 3ef7a489bf713acf341ca0e9cc7eeaf5 201 PANTHER PTHR34298:SF2 7 182 1.4E-58 T 23-04-2016 DC74_RS11035 3ef7a489bf713acf341ca0e9cc7eeaf5 201 Pfam PF04079 Segregation and condensation complex subunit ScpB 11 168 9.1E-55 T 23-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 DC74_RS11035 3ef7a489bf713acf341ca0e9cc7eeaf5 201 SUPERFAMILY SSF46785 86 159 8.34E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11035 3ef7a489bf713acf341ca0e9cc7eeaf5 201 Gene3D G3DSA:1.10.10.10 86 159 2.7E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11035 3ef7a489bf713acf341ca0e9cc7eeaf5 201 Gene3D G3DSA:1.10.10.10 7 82 5.6E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11035 3ef7a489bf713acf341ca0e9cc7eeaf5 201 PIRSF PIRSF019345 3 200 6.5E-51 T 23-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 DC74_RS11035 3ef7a489bf713acf341ca0e9cc7eeaf5 201 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 171 4.1E-29 T 23-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 DC74_RS11035 3ef7a489bf713acf341ca0e9cc7eeaf5 201 PANTHER PTHR34298 7 182 1.4E-58 T 23-04-2016 DC74_RS15425 87bd6e2b7b57e00323dc8f4820d65802 173 PIRSF PIRSF034110 1 173 1.0E-39 T 23-04-2016 IPR009593 Protein of unknown function DUF1203 DC74_RS15425 87bd6e2b7b57e00323dc8f4820d65802 173 Pfam PF06718 Protein of unknown function (DUF1203) 43 172 2.5E-36 T 23-04-2016 IPR009593 Protein of unknown function DUF1203 DC74_RS39225 74ca6c23ff2d83ce05f7cae86974b98d 195 PANTHER PTHR30055 4 188 1.5E-48 T 23-04-2016 DC74_RS39225 74ca6c23ff2d83ce05f7cae86974b98d 195 SUPERFAMILY SSF46689 6 73 4.04E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39225 74ca6c23ff2d83ce05f7cae86974b98d 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 47 6.2E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39225 74ca6c23ff2d83ce05f7cae86974b98d 195 SUPERFAMILY SSF48498 79 182 1.91E-20 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS39225 74ca6c23ff2d83ce05f7cae86974b98d 195 Pfam PF13305 WHG domain 85 160 1.3E-6 T 23-04-2016 IPR025996 WHG domain DC74_RS39225 74ca6c23ff2d83ce05f7cae86974b98d 195 Gene3D G3DSA:1.10.357.10 52 185 3.3E-40 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS39225 74ca6c23ff2d83ce05f7cae86974b98d 195 Gene3D G3DSA:1.10.10.60 3 50 6.6E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39225 74ca6c23ff2d83ce05f7cae86974b98d 195 PANTHER PTHR30055:SF87 4 188 1.5E-48 T 23-04-2016 DC74_RS29545 50d00a758055a65bd98dd9310eb0b1e3 98 Pfam PF00550 Phosphopantetheine attachment site 29 86 2.8E-7 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29545 50d00a758055a65bd98dd9310eb0b1e3 98 Gene3D G3DSA:1.10.1200.10 17 86 3.0E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29545 50d00a758055a65bd98dd9310eb0b1e3 98 SUPERFAMILY SSF47336 19 90 5.37E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS36960 74872a835f383c90635a94964b6cb5cf 290 PANTHER PTHR24362 33 247 5.4E-19 T 23-04-2016 DC74_RS36960 74872a835f383c90635a94964b6cb5cf 290 Gene3D G3DSA:1.10.510.10 103 227 3.5E-11 T 23-04-2016 DC74_RS36960 74872a835f383c90635a94964b6cb5cf 290 SUPERFAMILY SSF56112 53 244 3.37E-22 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS36960 74872a835f383c90635a94964b6cb5cf 290 PANTHER PTHR24362:SF160 33 247 5.4E-19 T 23-04-2016 DC74_RS18105 74d12a1bfe6d17616d8138cbf2dc2e5a 255 PANTHER PTHR12704 1 88 1.3E-50 T 23-04-2016 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 DC74_RS18105 74d12a1bfe6d17616d8138cbf2dc2e5a 255 PANTHER PTHR12704:SF1 1 88 1.3E-50 T 23-04-2016 DC74_RS18105 74d12a1bfe6d17616d8138cbf2dc2e5a 255 Gene3D G3DSA:1.10.3630.10 3 211 6.5E-40 T 23-04-2016 DC74_RS18105 74d12a1bfe6d17616d8138cbf2dc2e5a 255 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 202 5.4E-46 T 23-04-2016 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 DC74_RS20965 0edf2751a8dd44190cb54e6bd915129d 258 PANTHER PTHR30136 12 256 6.0E-49 T 23-04-2016 DC74_RS20965 0edf2751a8dd44190cb54e6bd915129d 258 SUPERFAMILY SSF46785 15 82 1.34E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20965 0edf2751a8dd44190cb54e6bd915129d 258 SUPERFAMILY SSF55781 86 248 1.24E-20 T 23-04-2016 IPR029016 GAF domain-like DC74_RS20965 0edf2751a8dd44190cb54e6bd915129d 258 Pfam PF09339 IclR helix-turn-helix domain 17 67 2.2E-14 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS20965 0edf2751a8dd44190cb54e6bd915129d 258 PANTHER PTHR30136:SF3 12 256 6.0E-49 T 23-04-2016 DC74_RS20965 0edf2751a8dd44190cb54e6bd915129d 258 SMART SM00346 15 95 7.5E-5 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS20965 0edf2751a8dd44190cb54e6bd915129d 258 Gene3D G3DSA:1.10.10.10 11 81 6.6E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20965 0edf2751a8dd44190cb54e6bd915129d 258 Pfam PF01614 Bacterial transcriptional regulator 139 246 6.0E-17 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS20965 0edf2751a8dd44190cb54e6bd915129d 258 Gene3D G3DSA:3.30.450.40 92 252 3.4E-25 T 23-04-2016 IPR029016 GAF domain-like DC74_RS16995 4dd1d35bdc877103c39de5fcf0f9e96d 329 Gene3D G3DSA:3.40.50.10680 87 328 2.7E-82 T 23-04-2016 DC74_RS16995 4dd1d35bdc877103c39de5fcf0f9e96d 329 PANTHER PTHR30135:SF2 1 323 2.0E-134 T 23-04-2016 DC74_RS16995 4dd1d35bdc877103c39de5fcf0f9e96d 329 Pfam PF01933 Uncharacterised protein family UPF0052 3 289 6.2E-62 T 23-04-2016 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 DC74_RS16995 4dd1d35bdc877103c39de5fcf0f9e96d 329 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 320 5.8E-129 T 23-04-2016 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198|UniPathway: UPA00071 DC74_RS16995 4dd1d35bdc877103c39de5fcf0f9e96d 329 SUPERFAMILY SSF142338 3 326 2.88E-86 T 23-04-2016 DC74_RS16995 4dd1d35bdc877103c39de5fcf0f9e96d 329 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 329 136.921 T 23-04-2016 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198|UniPathway: UPA00071 DC74_RS16995 4dd1d35bdc877103c39de5fcf0f9e96d 329 PANTHER PTHR30135 1 323 2.0E-134 T 23-04-2016 DC74_RS37745 3cef3edcac932da74c08494db679d1c6 162 Hamap MF_01151 Protein GrpE [grpE]. 2 151 14.579 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS37745 3cef3edcac932da74c08494db679d1c6 162 Gene3D G3DSA:3.90.20.20 5 69 1.0E-14 T 23-04-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil DC74_RS37745 3cef3edcac932da74c08494db679d1c6 162 Pfam PF01025 GrpE 5 150 2.4E-26 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS37745 3cef3edcac932da74c08494db679d1c6 162 SUPERFAMILY SSF58014 5 86 9.02E-14 T 23-04-2016 DC74_RS37745 3cef3edcac932da74c08494db679d1c6 162 PANTHER PTHR21237 3 155 3.2E-27 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS37745 3cef3edcac932da74c08494db679d1c6 162 Gene3D G3DSA:2.30.22.10 86 150 4.1E-14 T 23-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 DC74_RS37745 3cef3edcac932da74c08494db679d1c6 162 PRINTS PR00773 GrpE protein signature 94 109 2.0E-13 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS37745 3cef3edcac932da74c08494db679d1c6 162 PRINTS PR00773 GrpE protein signature 47 62 2.0E-13 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS37745 3cef3edcac932da74c08494db679d1c6 162 PRINTS PR00773 GrpE protein signature 19 35 2.0E-13 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS37745 3cef3edcac932da74c08494db679d1c6 162 SUPERFAMILY SSF51064 88 150 3.4E-10 T 23-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 DC74_RS20925 445a4b2597702900e06a375d8129d65b 276 PANTHER PTHR30212 2 159 5.8E-29 T 23-04-2016 DC74_RS20925 445a4b2597702900e06a375d8129d65b 276 Gene3D G3DSA:2.30.110.10 16 148 7.5E-21 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS20925 445a4b2597702900e06a375d8129d65b 276 SUPERFAMILY SSF50475 26 150 1.43E-13 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS20925 445a4b2597702900e06a375d8129d65b 276 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 27 118 4.0E-13 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS20925 445a4b2597702900e06a375d8129d65b 276 PANTHER PTHR30212:SF3 2 159 5.8E-29 T 23-04-2016 DC74_RS28390 0ba3476006db0cfa0d0ac473e44b924e 385 SUPERFAMILY SSF51717 45 219 5.18E-9 T 23-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 DC74_RS28390 0ba3476006db0cfa0d0ac473e44b924e 385 SUPERFAMILY SSF56014 274 359 2.27E-11 T 23-04-2016 DC74_RS28390 0ba3476006db0cfa0d0ac473e44b924e 385 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 4.7E-128 T 23-04-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 DC74_RS28390 0ba3476006db0cfa0d0ac473e44b924e 385 Pfam PF04551 GcpE protein 22 361 4.4E-133 T 23-04-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 DC74_RS28390 0ba3476006db0cfa0d0ac473e44b924e 385 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.376 T 23-04-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 DC74_RS28390 0ba3476006db0cfa0d0ac473e44b924e 385 PIRSF PIRSF004640 11 373 3.2E-144 T 23-04-2016 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 DC74_RS28390 0ba3476006db0cfa0d0ac473e44b924e 385 PANTHER PTHR30454 1 375 5.5E-199 T 23-04-2016 DC74_RS06280 1121968c5cbd9448f75bc7fc2393374b 443 Pfam PF07690 Major Facilitator Superfamily 265 439 5.1E-15 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS06280 1121968c5cbd9448f75bc7fc2393374b 443 Pfam PF00083 Sugar (and other) transporter 26 224 1.9E-26 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS06280 1121968c5cbd9448f75bc7fc2393374b 443 ProSitePatterns PS00217 Sugar transport proteins signature 2. 133 158 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS06280 1121968c5cbd9448f75bc7fc2393374b 443 SUPERFAMILY SSF103473 20 441 1.23E-64 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS06280 1121968c5cbd9448f75bc7fc2393374b 443 Gene3D G3DSA:1.20.1250.20 250 442 2.3E-23 T 23-04-2016 DC74_RS06280 1121968c5cbd9448f75bc7fc2393374b 443 Gene3D G3DSA:1.20.1250.20 20 225 7.1E-24 T 23-04-2016 DC74_RS06280 1121968c5cbd9448f75bc7fc2393374b 443 ProSitePatterns PS00216 Sugar transport proteins signature 1. 306 323 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS06280 1121968c5cbd9448f75bc7fc2393374b 443 PANTHER PTHR23508 20 441 5.1E-110 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PANTHER PTHR22912:SF141 225 353 6.0E-54 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PANTHER PTHR22912:SF141 1 201 6.0E-54 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PIRSF PIRSF037495 1 495 5.6E-120 T 23-04-2016 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.0E-13 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 327 334 1.0E-13 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 1.0E-13 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 127 136 1.0E-13 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PANTHER PTHR22912 225 353 6.0E-54 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PANTHER PTHR22912 1 201 6.0E-54 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 Gene3D G3DSA:3.50.50.60 3 133 1.7E-15 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 294 2.8E-21 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 2.8E-21 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.8E-21 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 2.8E-21 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 312 334 2.8E-21 T 23-04-2016 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 SUPERFAMILY SSF51905 1 355 4.34E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 Pfam PF04324 BFD-like [2Fe-2S] binding domain 399 451 4.4E-7 T 23-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 Gene3D G3DSA:3.50.50.60 134 350 8.6E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38620 cac358c5c6494078d92def072cb905f5 505 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 346 2.0E-21 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS13605 594caac4518d0f88e40ca833cf0c344f 219 Gene3D G3DSA:3.40.50.150 48 178 1.8E-12 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS13605 594caac4518d0f88e40ca833cf0c344f 219 Pfam PF13578 Methyltransferase domain 48 176 1.2E-22 T 23-04-2016 DC74_RS13605 594caac4518d0f88e40ca833cf0c344f 219 SUPERFAMILY SSF53335 46 197 5.97E-15 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS31390 1a8ec97f8f4d659c3b7faae80ec83493 293 SUPERFAMILY SSF55729 170 287 3.48E-13 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31390 1a8ec97f8f4d659c3b7faae80ec83493 293 Pfam PF00583 Acetyltransferase (GNAT) family 28 104 8.0E-7 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS31390 1a8ec97f8f4d659c3b7faae80ec83493 293 Pfam PF00583 Acetyltransferase (GNAT) family 202 280 1.6E-4 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS31390 1a8ec97f8f4d659c3b7faae80ec83493 293 SUPERFAMILY SSF55729 15 112 2.13E-13 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31390 1a8ec97f8f4d659c3b7faae80ec83493 293 Gene3D G3DSA:3.40.630.30 170 285 7.4E-13 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31390 1a8ec97f8f4d659c3b7faae80ec83493 293 Gene3D G3DSA:3.40.630.30 15 113 7.0E-13 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 Gene3D G3DSA:3.40.50.720 308 543 4.9E-69 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 446 474 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 Pfam PF00106 short chain dehydrogenase 310 499 6.2E-55 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 309 490 0.0014 T 23-04-2016 DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 Gene3D G3DSA:3.40.50.1820 1 284 7.8E-48 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 PANTHER PTHR24322 459 490 8.7E-56 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 PANTHER PTHR24322 313 443 8.7E-56 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 480 497 4.1E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 310 327 4.1E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 433 449 4.1E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 385 396 4.1E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 459 478 4.1E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 SUPERFAMILY SSF53474 1 285 1.13E-42 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 385 396 3.7E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 439 447 3.7E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 459 478 3.7E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 SUPERFAMILY SSF51735 305 571 3.95E-70 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS21080 e10b1a8c22b551a1aad9b0d36974a082 576 Pfam PF00561 alpha/beta hydrolase fold 19 133 3.0E-20 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS38330 d09ae6b67df0fb3a8e76e243ab502cae 302 Gene3D G3DSA:1.10.10.10 1 85 1.7E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38330 d09ae6b67df0fb3a8e76e243ab502cae 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 59 9.6E-21 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS38330 d09ae6b67df0fb3a8e76e243ab502cae 302 Pfam PF03466 LysR substrate binding domain 88 294 2.8E-22 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS38330 d09ae6b67df0fb3a8e76e243ab502cae 302 SUPERFAMILY SSF46785 1 104 1.36E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38330 d09ae6b67df0fb3a8e76e243ab502cae 302 Gene3D G3DSA:3.40.190.10 183 267 4.2E-18 T 23-04-2016 DC74_RS38330 d09ae6b67df0fb3a8e76e243ab502cae 302 Gene3D G3DSA:3.40.190.10 90 182 2.8E-12 T 23-04-2016 DC74_RS38330 d09ae6b67df0fb3a8e76e243ab502cae 302 PANTHER PTHR30346 1 279 2.0E-49 T 23-04-2016 DC74_RS38330 d09ae6b67df0fb3a8e76e243ab502cae 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.7E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS38330 d09ae6b67df0fb3a8e76e243ab502cae 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.7E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS38330 d09ae6b67df0fb3a8e76e243ab502cae 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.7E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS38330 d09ae6b67df0fb3a8e76e243ab502cae 302 SUPERFAMILY SSF53850 90 297 1.52E-23 T 23-04-2016 DC74_RS19940 85463cd89cc89fd2dd7a6e08b6ae39c9 151 PANTHER PTHR30204:SF8 13 118 1.4E-34 T 23-04-2016 DC74_RS19940 85463cd89cc89fd2dd7a6e08b6ae39c9 151 SMART SM00422 21 90 1.8E-24 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS19940 85463cd89cc89fd2dd7a6e08b6ae39c9 151 ProSitePatterns PS00552 MerR-type HTH domain signature. 24 46 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS19940 85463cd89cc89fd2dd7a6e08b6ae39c9 151 Gene3D G3DSA:1.10.1660.10 22 118 4.2E-21 T 23-04-2016 DC74_RS19940 85463cd89cc89fd2dd7a6e08b6ae39c9 151 SUPERFAMILY SSF46955 21 112 1.01E-18 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS19940 85463cd89cc89fd2dd7a6e08b6ae39c9 151 Pfam PF13411 MerR HTH family regulatory protein 21 88 1.3E-16 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS19940 85463cd89cc89fd2dd7a6e08b6ae39c9 151 PANTHER PTHR30204 13 118 1.4E-34 T 23-04-2016 DC74_RS06870 09f928f3088aab213c64971c1942f540 602 Pfam PF00664 ABC transporter transmembrane region 31 308 5.3E-58 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS06870 09f928f3088aab213c64971c1942f540 602 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS06870 09f928f3088aab213c64971c1942f540 602 PANTHER PTHR24221 12 599 3.0E-290 T 23-04-2016 DC74_RS06870 09f928f3088aab213c64971c1942f540 602 SUPERFAMILY SSF90123 16 341 1.57E-81 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS06870 09f928f3088aab213c64971c1942f540 602 SUPERFAMILY SSF52540 346 587 6.61E-89 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06870 09f928f3088aab213c64971c1942f540 602 Pfam PF00005 ABC transporter 372 520 4.0E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS06870 09f928f3088aab213c64971c1942f540 602 SMART SM00382 380 572 1.7E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS06870 09f928f3088aab213c64971c1942f540 602 Gene3D G3DSA:3.40.50.300 355 584 1.2E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06870 09f928f3088aab213c64971c1942f540 602 Gene3D G3DSA:1.20.1560.10 16 340 5.1E-84 T 23-04-2016 DC74_RS06870 09f928f3088aab213c64971c1942f540 602 PANTHER PTHR24221:SF271 12 599 3.0E-290 T 23-04-2016 DC74_RS12015 e60f7d46ac59f347cbe9e39033efda24 663 Gene3D G3DSA:3.40.50.300 3 241 1.5E-25 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12015 e60f7d46ac59f347cbe9e39033efda24 663 Pfam PF13538 UvrD-like helicase C-terminal domain 415 476 3.4E-8 T 23-04-2016 IPR027785 UvrD-like helicase C-terminal domain DC74_RS12015 e60f7d46ac59f347cbe9e39033efda24 663 Pfam PF00580 UvrD/REP helicase N-terminal domain 208 252 3.9E-10 T 23-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 DC74_RS12015 e60f7d46ac59f347cbe9e39033efda24 663 Gene3D G3DSA:3.40.50.300 242 333 2.1E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12015 e60f7d46ac59f347cbe9e39033efda24 663 Gene3D G3DSA:3.40.50.300 403 478 2.1E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12015 e60f7d46ac59f347cbe9e39033efda24 663 SUPERFAMILY SSF52540 159 484 9.5E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12015 e60f7d46ac59f347cbe9e39033efda24 663 SUPERFAMILY SSF52540 3 92 9.5E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12015 e60f7d46ac59f347cbe9e39033efda24 663 PANTHER PTHR11070 1 478 1.4E-37 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS15110 790ac0e0635bf5528f3efb965c33a444 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 280 1.8E-86 T 23-04-2016 IPR003797 DegV DC74_RS15110 790ac0e0635bf5528f3efb965c33a444 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 278 3.8E-88 T 23-04-2016 IPR003797 DegV DC74_RS15110 790ac0e0635bf5528f3efb965c33a444 281 PANTHER PTHR33434:SF2 3 281 1.2E-81 T 23-04-2016 DC74_RS15110 790ac0e0635bf5528f3efb965c33a444 281 Gene3D G3DSA:3.30.1180.10 155 279 8.5E-44 T 23-04-2016 DC74_RS15110 790ac0e0635bf5528f3efb965c33a444 281 SUPERFAMILY SSF82549 5 280 8.37E-77 T 23-04-2016 DC74_RS15110 790ac0e0635bf5528f3efb965c33a444 281 PANTHER PTHR33434 3 281 1.2E-81 T 23-04-2016 DC74_RS15110 790ac0e0635bf5528f3efb965c33a444 281 Gene3D G3DSA:3.40.50.10170 5 150 3.6E-43 T 23-04-2016 DC74_RS18005 17de927b6e9a025fa1ee4d269be54c1d 124 PANTHER PTHR35176:SF3 1 105 4.9E-12 T 23-04-2016 DC74_RS18005 17de927b6e9a025fa1ee4d269be54c1d 124 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 1 79 5.9E-12 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS18005 17de927b6e9a025fa1ee4d269be54c1d 124 PANTHER PTHR35176 1 105 4.9E-12 T 23-04-2016 DC74_RS18005 17de927b6e9a025fa1ee4d269be54c1d 124 SUPERFAMILY SSF50475 1 110 4.49E-18 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS18005 17de927b6e9a025fa1ee4d269be54c1d 124 TIGRFAM TIGR04023 PPOX_MSMEG_5819: PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family 1 107 1.7E-25 T 23-04-2016 IPR024031 PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family DC74_RS18005 17de927b6e9a025fa1ee4d269be54c1d 124 Gene3D G3DSA:2.30.110.10 1 110 6.6E-16 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 SUPERFAMILY SSF52540 360 407 1.54E-81 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 SUPERFAMILY SSF52540 3 226 1.54E-81 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 827 0.0 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 Pfam PF07516 SecA Wing and Scaffold domain 624 838 1.1E-65 T 23-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 Gene3D G3DSA:3.40.50.300 409 626 4.8E-93 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 Gene3D G3DSA:1.10.3060.10 655 839 9.6E-58 T 23-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 Pfam PF01043 SecA preprotein cross-linking domain 231 350 3.7E-33 T 23-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 SMART SM00958 226 350 7.0E-63 T 23-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 PRINTS PR00906 SecA protein signature 331 353 5.0E-72 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 PRINTS PR00906 SecA protein signature 115 125 5.0E-72 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 PRINTS PR00906 SecA protein signature 99 113 5.0E-72 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 PRINTS PR00906 SecA protein signature 405 418 5.0E-72 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 PRINTS PR00906 SecA protein signature 368 385 5.0E-72 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 PRINTS PR00906 SecA protein signature 61 85 5.0E-72 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 PRINTS PR00906 SecA protein signature 168 188 5.0E-72 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 ProSitePatterns PS01312 SecA family signature. 492 507 - T 23-04-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 SUPERFAMILY SSF81767 225 360 3.4E-40 T 23-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 SMART SM00957 4 394 8.9E-283 T 23-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 Pfam PF07517 SecA DEAD-like domain 5 393 3.9E-129 T 23-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 SUPERFAMILY SSF81886 627 851 4.32E-74 T 23-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 841 19.952 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 SUPERFAMILY SSF52540 408 625 6.63E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 Gene3D G3DSA:3.40.50.300 3 226 2.6E-123 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 Gene3D G3DSA:3.40.50.300 361 408 2.6E-123 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 Gene3D G3DSA:3.90.1440.10 229 360 7.0E-44 T 23-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 PANTHER PTHR30612 557 849 0.0 T 23-04-2016 DC74_RS16835 b03a87f369ad4de9edc3cf267584c6a1 940 PANTHER PTHR30612 14 512 0.0 T 23-04-2016 DC74_RS38855 668a31f4c9c33c15d924d829de0d9a5f 300 SUPERFAMILY SSF51197 18 246 2.29E-47 T 23-04-2016 DC74_RS38855 668a31f4c9c33c15d924d829de0d9a5f 300 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 23 207 2.4E-29 T 23-04-2016 IPR008775 Phytanoyl-CoA dioxygenase DC74_RS38855 668a31f4c9c33c15d924d829de0d9a5f 300 PANTHER PTHR20883:SF0 7 272 1.4E-21 T 23-04-2016 DC74_RS38855 668a31f4c9c33c15d924d829de0d9a5f 300 Gene3D G3DSA:2.60.120.620 16 223 2.0E-32 T 23-04-2016 DC74_RS38855 668a31f4c9c33c15d924d829de0d9a5f 300 PANTHER PTHR20883 7 272 1.4E-21 T 23-04-2016 DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 SMART SM00450 258 354 6.1 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 SMART SM00450 363 458 4.1E-19 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 Gene3D G3DSA:3.40.250.10 258 339 2.9E-11 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 SUPERFAMILY SSF52821 227 339 1.96E-13 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 PANTHER PTHR11935 2 245 1.3E-77 T 23-04-2016 DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 SMART SM00849 12 185 3.2E-24 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 Gene3D G3DSA:3.40.250.10 352 453 5.7E-25 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 SUPERFAMILY SSF56281 12 236 1.05E-43 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 Pfam PF00581 Rhodanese-like domain 364 453 3.2E-10 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 Pfam PF00581 Rhodanese-like domain 261 309 2.0E-4 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 Pfam PF00753 Metallo-beta-lactamase superfamily 11 185 1.3E-7 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 Gene3D G3DSA:3.60.15.10 10 236 3.6E-51 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 SUPERFAMILY SSF52821 350 454 9.3E-28 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS05590 087e7844f7f28acfdb1571e6a6f8c90f 460 PANTHER PTHR11935:SF9 2 245 1.3E-77 T 23-04-2016 DC74_RS35690 291e37b9898448da18044165656314dc 189 PANTHER PTHR10458 13 172 1.1E-65 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS35690 291e37b9898448da18044165656314dc 189 PRINTS PR01576 Peptide deformylase signature 43 72 3.0E-32 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS35690 291e37b9898448da18044165656314dc 189 PRINTS PR01576 Peptide deformylase signature 114 132 3.0E-32 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS35690 291e37b9898448da18044165656314dc 189 PRINTS PR01576 Peptide deformylase signature 102 113 3.0E-32 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS35690 291e37b9898448da18044165656314dc 189 PRINTS PR01576 Peptide deformylase signature 133 162 3.0E-32 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS35690 291e37b9898448da18044165656314dc 189 Hamap MF_00163 Peptide deformylase [def]. 12 175 28.368 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS35690 291e37b9898448da18044165656314dc 189 SUPERFAMILY SSF56420 13 171 1.44E-57 T 23-04-2016 IPR023635 Peptide deformylase DC74_RS35690 291e37b9898448da18044165656314dc 189 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 19 168 1.7E-39 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS35690 291e37b9898448da18044165656314dc 189 PIRSF PIRSF004749 2 186 9.3E-46 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS35690 291e37b9898448da18044165656314dc 189 Pfam PF01327 Polypeptide deformylase 16 164 1.3E-45 T 23-04-2016 IPR023635 Peptide deformylase DC74_RS35690 291e37b9898448da18044165656314dc 189 Gene3D G3DSA:3.90.45.10 15 179 6.1E-61 T 23-04-2016 IPR023635 Peptide deformylase DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 SUPERFAMILY SSF56784 432 605 5.67E-36 T 23-04-2016 IPR023214 HAD-like domain DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 SUPERFAMILY SSF56784 291 310 5.67E-36 T 23-04-2016 IPR023214 HAD-like domain DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 Gene3D G3DSA:3.40.1110.10 428 485 1.4E-35 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 Gene3D G3DSA:3.40.1110.10 304 378 1.4E-35 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 Gene3D G3DSA:2.70.150.10 26 195 6.8E-22 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 1 721 38.739 T 23-04-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 PANTHER PTHR24093:SF49 5 628 2.7E-302 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 Gene3D G3DSA:3.40.50.1000 486 604 3.3E-36 T 23-04-2016 IPR023214 HAD-like domain DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 Pfam PF00702 haloacid dehalogenase-like hydrolase 288 571 4.6E-28 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 54 314 9.3E-29 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 478 646 1.6E-39 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 294 300 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 PANTHER PTHR24093 5 628 2.7E-302 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 504 514 7.4E-25 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 141 155 7.4E-25 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 580 592 7.4E-25 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 292 306 7.4E-25 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 576 7.4E-25 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 PANTHER PTHR24093 666 720 2.7E-302 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 PANTHER PTHR24093:SF49 666 720 2.7E-302 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 SUPERFAMILY SSF81653 102 194 5.23E-20 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 SUPERFAMILY SSF81665 195 286 5.23E-10 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 SUPERFAMILY SSF81665 21 84 5.23E-10 T 23-04-2016 DC74_RS04010 b770b526982dbac6d0f89b6f2ada85ad 724 Pfam PF00122 E1-E2 ATPase 53 283 1.2E-38 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS11845 77c66bac93b3f0f0f731ed4968fe435e 301 PANTHER PTHR30448 9 301 7.7E-153 T 23-04-2016 DC74_RS11845 77c66bac93b3f0f0f731ed4968fe435e 301 Pfam PF03668 P-loop ATPase protein family 19 301 8.5E-109 T 23-04-2016 IPR005337 RapZ-like family GO:0005524 DC74_RS11845 77c66bac93b3f0f0f731ed4968fe435e 301 Gene3D G3DSA:3.40.50.300 14 172 7.2E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11845 77c66bac93b3f0f0f731ed4968fe435e 301 SUPERFAMILY SSF52540 19 171 9.74E-15 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11845 77c66bac93b3f0f0f731ed4968fe435e 301 PIRSF PIRSF005052 18 301 4.5E-110 T 23-04-2016 IPR005337 RapZ-like family GO:0005524 DC74_RS11845 77c66bac93b3f0f0f731ed4968fe435e 301 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 18 300 40.853 T 23-04-2016 IPR005337 RapZ-like family GO:0005524 DC74_RS11845 77c66bac93b3f0f0f731ed4968fe435e 301 PANTHER PTHR30448:SF0 9 301 7.7E-153 T 23-04-2016 DC74_RS36775 8e530dee2caf993b5b47d39d1d3ccd2e 330 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 50 316 1.2E-62 T 23-04-2016 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 DC74_RS36775 8e530dee2caf993b5b47d39d1d3ccd2e 330 PANTHER PTHR30024 14 316 1.0E-76 T 23-04-2016 DC74_RS36775 8e530dee2caf993b5b47d39d1d3ccd2e 330 SMART SM00062 32 246 1.6E-11 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS36775 8e530dee2caf993b5b47d39d1d3ccd2e 330 Pfam PF09084 NMT1/THI5 like 72 249 4.3E-16 T 23-04-2016 IPR015168 SsuA/THI5-like DC74_RS36775 8e530dee2caf993b5b47d39d1d3ccd2e 330 SUPERFAMILY SSF53850 35 252 2.18E-43 T 23-04-2016 DC74_RS36775 8e530dee2caf993b5b47d39d1d3ccd2e 330 PANTHER PTHR30024:SF3 14 316 1.0E-76 T 23-04-2016 DC74_RS36775 8e530dee2caf993b5b47d39d1d3ccd2e 330 Gene3D G3DSA:3.40.190.10 111 230 6.5E-25 T 23-04-2016 DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 SUPERFAMILY SSF55781 14 183 4.8E-29 T 23-04-2016 IPR029016 GAF domain-like DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 Gene3D G3DSA:3.30.450.40 14 178 2.7E-29 T 23-04-2016 IPR029016 GAF domain-like DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 SUPERFAMILY SSF55874 255 383 7.07E-22 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 Pfam PF13185 GAF domain 23 170 1.2E-19 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 295 383 6.3E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 PANTHER PTHR24421 156 383 5.1E-49 T 23-04-2016 DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 SMART SM00065 24 180 6.0E-17 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 Gene3D G3DSA:3.30.565.10 262 383 2.4E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 Pfam PF07730 Histidine kinase 187 254 4.1E-17 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 SMART SM00387 291 385 4.1E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 383 3.1E-5 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 364 3.1E-5 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS11270 60e09f69d151e5f42de29748f062dfef 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 341 3.1E-5 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS32715 f2990ba3fa9b20f6b29c6344a668abb3 329 Pfam PF00196 Bacterial regulatory proteins, luxR family 278 321 1.8E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32715 f2990ba3fa9b20f6b29c6344a668abb3 329 SUPERFAMILY SSF56024 120 274 3.92E-5 T 23-04-2016 DC74_RS32715 f2990ba3fa9b20f6b29c6344a668abb3 329 SMART SM00421 276 325 4.7E-4 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32715 f2990ba3fa9b20f6b29c6344a668abb3 329 Gene3D G3DSA:3.30.870.10 121 262 6.1E-5 T 23-04-2016 DC74_RS32715 f2990ba3fa9b20f6b29c6344a668abb3 329 SUPERFAMILY SSF46894 277 325 8.84E-9 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS32715 f2990ba3fa9b20f6b29c6344a668abb3 329 Gene3D G3DSA:1.10.10.10 277 324 1.1E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17520 f1952f56c2edcf8983baefa2539686a3 233 PANTHER PTHR30328 16 232 2.1E-98 T 23-04-2016 DC74_RS17520 f1952f56c2edcf8983baefa2539686a3 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 56 1.2E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS17520 f1952f56c2edcf8983baefa2539686a3 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 64 87 1.2E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS17520 f1952f56c2edcf8983baefa2539686a3 233 SUPERFAMILY SSF46689 29 109 8.72E-22 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS17520 f1952f56c2edcf8983baefa2539686a3 233 ProSitePatterns PS01081 TetR-type HTH domain signature. 55 85 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS17520 f1952f56c2edcf8983baefa2539686a3 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 43 87 1.8E-17 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS17520 f1952f56c2edcf8983baefa2539686a3 233 Gene3D G3DSA:1.10.357.10 26 219 4.2E-47 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS17520 f1952f56c2edcf8983baefa2539686a3 233 PANTHER PTHR30328:SF12 16 232 2.1E-98 T 23-04-2016 DC74_RS17520 f1952f56c2edcf8983baefa2539686a3 233 SUPERFAMILY SSF48498 110 220 8.81E-7 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS37560 27212eb8ce8ba55cbaf0e5cd4717601f 388 SUPERFAMILY SSF56645 12 248 3.4E-60 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS37560 27212eb8ce8ba55cbaf0e5cd4717601f 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 277 384 2.1E-8 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS37560 27212eb8ce8ba55cbaf0e5cd4717601f 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 127 2.5E-20 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS37560 27212eb8ce8ba55cbaf0e5cd4717601f 388 PANTHER PTHR10909:SF242 12 380 5.0E-67 T 23-04-2016 DC74_RS37560 27212eb8ce8ba55cbaf0e5cd4717601f 388 Gene3D G3DSA:1.20.140.10 228 383 9.7E-11 T 23-04-2016 DC74_RS37560 27212eb8ce8ba55cbaf0e5cd4717601f 388 SUPERFAMILY SSF47203 238 382 1.69E-8 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS37560 27212eb8ce8ba55cbaf0e5cd4717601f 388 PANTHER PTHR10909 12 380 5.0E-67 T 23-04-2016 DC74_RS37560 27212eb8ce8ba55cbaf0e5cd4717601f 388 Gene3D G3DSA:1.10.540.10 12 128 4.7E-22 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS37560 27212eb8ce8ba55cbaf0e5cd4717601f 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 224 3.1E-19 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS37560 27212eb8ce8ba55cbaf0e5cd4717601f 388 Gene3D G3DSA:2.40.110.10 132 227 2.3E-26 T 23-04-2016 DC74_RS37560 27212eb8ce8ba55cbaf0e5cd4717601f 388 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 134 146 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 Pfam PF02310 B12 binding domain 735 851 2.0E-20 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 Gene3D G3DSA:3.20.20.20 357 619 2.8E-84 T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 PIRSF PIRSF000381 10 1169 0.0 T 23-04-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 TIGRFAM TIGR02082 metH: methionine synthase 22 1167 0.0 T 23-04-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 SUPERFAMILY SSF47644 646 728 2.48E-24 T 23-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 PANTHER PTHR21091:SF97 19 392 8.1E-119 T 23-04-2016 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 Pfam PF02607 B12 binding domain 650 722 1.3E-24 T 23-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 PANTHER PTHR21091 19 392 8.1E-119 T 23-04-2016 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 SMART SM01018 647 729 7.0E-42 T 23-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 Gene3D G3DSA:1.10.1240.10 641 726 1.7E-31 T 23-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 Gene3D G3DSA:3.40.50.280 732 862 1.3E-46 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 Gene3D G3DSA:3.20.20.330 12 356 5.2E-105 T 23-04-2016 IPR003726 Homocysteine-binding domain DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 SUPERFAMILY SSF51717 349 620 7.33E-74 T 23-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 Pfam PF02574 Homocysteine S-methyltransferase 26 317 5.7E-66 T 23-04-2016 IPR003726 Homocysteine-binding domain DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 SUPERFAMILY SSF82282 16 391 6.67E-104 T 23-04-2016 IPR003726 Homocysteine-binding domain DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 Gene3D G3DSA:3.10.196.10 949 1167 2.7E-72 T 23-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 Pfam PF00809 Pterin binding enzyme 352 588 5.5E-45 T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 SUPERFAMILY SSF56507 892 1168 1.83E-95 T 23-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 967 1167 1.9E-40 T 23-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 DC74_RS10380 2d026bded12ada29a93ce731709f0843 1169 SUPERFAMILY SSF52242 729 864 2.22E-38 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS05220 2247f10262ee0feb1a26c6d2352c5f72 283 Pfam PF13560 Helix-turn-helix domain 5 84 9.2E-17 T 23-04-2016 DC74_RS05220 2247f10262ee0feb1a26c6d2352c5f72 283 PANTHER PTHR35010:SF1 1 279 5.5E-145 T 23-04-2016 DC74_RS05220 2247f10262ee0feb1a26c6d2352c5f72 283 SUPERFAMILY SSF47413 29 80 4.07E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS05220 2247f10262ee0feb1a26c6d2352c5f72 283 Gene3D G3DSA:1.10.260.40 4 80 1.8E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS05220 2247f10262ee0feb1a26c6d2352c5f72 283 PANTHER PTHR35010 1 279 5.5E-145 T 23-04-2016 DC74_RS05220 2247f10262ee0feb1a26c6d2352c5f72 283 SMART SM00530 9 81 2.9E-7 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS25385 87e1b9acb9c442dedb489e1884d41a7c 323 SMART SM00636 35 304 2.5E-6 T 23-04-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 DC74_RS25385 87e1b9acb9c442dedb489e1884d41a7c 323 PANTHER PTHR11177 6 307 1.5E-45 T 23-04-2016 DC74_RS25385 87e1b9acb9c442dedb489e1884d41a7c 323 ProSitePatterns PS01095 Chitinases family 18 active site. 142 150 - T 23-04-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 DC74_RS25385 87e1b9acb9c442dedb489e1884d41a7c 323 PANTHER PTHR11177:SF195 6 307 1.5E-45 T 23-04-2016 DC74_RS25385 87e1b9acb9c442dedb489e1884d41a7c 323 Gene3D G3DSA:3.20.20.80 34 312 4.9E-59 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS25385 87e1b9acb9c442dedb489e1884d41a7c 323 Pfam PF00704 Glycosyl hydrolases family 18 38 304 4.9E-26 T 23-04-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 DC74_RS25385 87e1b9acb9c442dedb489e1884d41a7c 323 SUPERFAMILY SSF51445 33 311 3.97E-53 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 Gene3D G3DSA:3.40.50.670 465 685 3.1E-74 T 23-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 SMART SM00387 48 208 4.1E-23 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR00418 DNA topoisomerase II family signature 87 100 6.4E-59 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR00418 DNA topoisomerase II family signature 325 338 6.4E-59 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR00418 DNA topoisomerase II family signature 547 563 6.4E-59 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR00418 DNA topoisomerase II family signature 52 67 6.4E-59 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR00418 DNA topoisomerase II family signature 636 652 6.4E-59 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR00418 DNA topoisomerase II family signature 565 582 6.4E-59 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR00418 DNA topoisomerase II family signature 130 144 6.4E-59 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR00418 DNA topoisomerase II family signature 481 495 6.4E-59 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR00418 DNA topoisomerase II family signature 585 597 6.4E-59 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 SUPERFAMILY SSF54211 259 451 9.67E-39 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 Gene3D G3DSA:3.30.230.10 258 451 2.3E-49 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR01159 DNA gyrase subunit B signature 229 242 2.0E-36 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR01159 DNA gyrase subunit B signature 673 689 2.0E-36 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR01159 DNA gyrase subunit B signature 369 385 2.0E-36 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR01159 DNA gyrase subunit B signature 531 540 2.0E-36 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR01159 DNA gyrase subunit B signature 258 280 2.0E-36 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR01159 DNA gyrase subunit B signature 214 229 2.0E-36 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR01159 DNA gyrase subunit B signature 657 669 2.0E-36 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR01159 DNA gyrase subunit B signature 23 33 2.0E-36 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PRINTS PR01159 DNA gyrase subunit B signature 435 455 2.0E-36 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 48 158 1.9E-21 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 SUPERFAMILY SSF55874 23 242 3.67E-59 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 Gene3D G3DSA:3.30.565.10 23 243 6.9E-82 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 Pfam PF01751 Toprim domain 480 581 1.1E-14 T 23-04-2016 IPR006171 Toprim domain DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PANTHER PTHR10169 1 705 1.7E-225 T 23-04-2016 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 Pfam PF00204 DNA gyrase B 259 451 3.1E-55 T 23-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 PANTHER PTHR10169:SF20 1 705 1.7E-225 T 23-04-2016 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 ProSitePatterns PS00177 DNA topoisomerase II signature. 483 491 - T 23-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 SMART SM00433 52 697 9.4E-280 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 SUPERFAMILY SSF56719 455 700 5.49E-75 T 23-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 DC74_RS29020 2f5f4be52153451dbd4635ede808685a 706 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 635 692 7.5E-25 T 23-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS11360 0a94c6cf642fadca3e489b49b8e31403 141 PANTHER PTHR38441 5 115 4.8E-34 T 23-04-2016 DC74_RS11360 0a94c6cf642fadca3e489b49b8e31403 141 Pfam PF04341 Protein of unknown function, DUF485 21 107 5.3E-31 T 23-04-2016 IPR007436 Protein of unknown function DUF485 DC74_RS11360 0a94c6cf642fadca3e489b49b8e31403 141 PANTHER PTHR38441:SF1 5 115 4.8E-34 T 23-04-2016 DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 SMART SM01043 94 239 3.1E-45 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 SUPERFAMILY SSF46894 3 87 5.39E-8 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 SUPERFAMILY SSF48452 753 939 4.32E-13 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 SUPERFAMILY SSF52540 249 504 1.13E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 Gene3D G3DSA:3.40.50.300 258 390 8.6E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 PANTHER PTHR35807 1 252 5.0E-49 T 23-04-2016 DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 SMART SM00862 16 87 1.9E-7 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 Gene3D G3DSA:1.10.10.10 14 88 5.4E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 Pfam PF03704 Bacterial transcriptional activator domain 94 239 5.4E-43 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 SUPERFAMILY SSF48452 89 257 7.59E-37 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 Gene3D G3DSA:1.25.40.10 746 884 6.9E-15 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 86 3.6E-6 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 SMART SM00028 749 782 280.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 SMART SM00028 99 132 450.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 SMART SM00028 868 901 1.4 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 SMART SM00028 910 943 25.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS39640 558c2a6f55f2e1fc82b06c0a29c909c6 972 Gene3D G3DSA:1.25.40.10 885 939 1.5E-8 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS13835 dc79f1f7d01007b468c26765e519b930 218 PANTHER PTHR10285:SF81 2 217 2.2E-57 T 23-04-2016 DC74_RS13835 dc79f1f7d01007b468c26765e519b930 218 Gene3D G3DSA:3.40.50.300 8 205 2.1E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS13835 dc79f1f7d01007b468c26765e519b930 218 PANTHER PTHR10285 2 217 2.2E-57 T 23-04-2016 DC74_RS13835 dc79f1f7d01007b468c26765e519b930 218 SUPERFAMILY SSF52540 16 210 8.91E-32 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02590 f23d4df1b01e0b4405bf887d92a01b76 134 Gene3D G3DSA:3.10.450.50 4 109 4.8E-11 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS02590 f23d4df1b01e0b4405bf887d92a01b76 134 SUPERFAMILY SSF54427 7 123 1.91E-23 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS02590 f23d4df1b01e0b4405bf887d92a01b76 134 Pfam PF12680 SnoaL-like domain 11 102 1.5E-6 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS20705 2b740da97e9cdbdd7867a12a6464601e 105 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 23.543 T 23-04-2016 IPR002696 Putative membrane protein insertion efficiency factor DC74_RS20705 2b740da97e9cdbdd7867a12a6464601e 105 Pfam PF01809 Haemolytic domain 5 68 4.1E-27 T 23-04-2016 IPR002696 Putative membrane protein insertion efficiency factor DC74_RS20705 2b740da97e9cdbdd7867a12a6464601e 105 SMART SM01234 1 68 1.4E-39 T 23-04-2016 IPR002696 Putative membrane protein insertion efficiency factor DC74_RS20705 2b740da97e9cdbdd7867a12a6464601e 105 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 2.0E-25 T 23-04-2016 IPR002696 Putative membrane protein insertion efficiency factor DC74_RS20705 2b740da97e9cdbdd7867a12a6464601e 105 PANTHER PTHR33383 2 97 1.0E-39 T 23-04-2016 DC74_RS20705 2b740da97e9cdbdd7867a12a6464601e 105 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 73 1.1E-25 T 23-04-2016 IPR002696 Putative membrane protein insertion efficiency factor DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 ProSitePatterns PS00802 Transketolase signature 2. 491 507 - T 23-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 Gene3D G3DSA:3.40.50.970 351 564 1.5E-72 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 PANTHER PTHR11624 12 331 0.0 T 23-04-2016 IPR033247 Transketolase family DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 Gene3D G3DSA:3.40.50.970 13 341 3.7E-111 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 PANTHER PTHR11624 358 700 0.0 T 23-04-2016 IPR033247 Transketolase family DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 PANTHER PTHR11624:SF1 358 700 0.0 T 23-04-2016 DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 PANTHER PTHR11624:SF1 12 331 0.0 T 23-04-2016 DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 16 355 3.9E-138 T 23-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 Gene3D G3DSA:3.40.50.920 565 695 1.9E-46 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 ProSitePatterns PS00801 Transketolase signature 1. 24 44 - T 23-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 SMART SM00861 371 555 1.4E-61 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 SUPERFAMILY SSF52922 560 696 6.41E-39 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 Pfam PF02780 Transketolase, C-terminal domain 581 687 4.6E-11 T 23-04-2016 IPR033248 Transketolase, C-terminal domain DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 TIGRFAM TIGR00232 tktlase_bact: transketolase 19 693 1.3E-237 T 23-04-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 Pfam PF02779 Transketolase, pyrimidine binding domain 370 533 1.3E-42 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 SUPERFAMILY SSF52518 358 556 1.89E-62 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS11775 0393ce3a7538e06bbc1bdb18a1cf3a4b 700 SUPERFAMILY SSF52518 6 341 1.96E-104 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS26625 3aa80f45e1b9b2933dcae10fa397c763 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS26625 3aa80f45e1b9b2933dcae10fa397c763 250 Pfam PF00005 ABC transporter 17 175 8.5E-33 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS26625 3aa80f45e1b9b2933dcae10fa397c763 250 SUPERFAMILY SSF52540 1 245 1.86E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26625 3aa80f45e1b9b2933dcae10fa397c763 250 PANTHER PTHR24220:SF327 3 250 2.7E-138 T 23-04-2016 DC74_RS26625 3aa80f45e1b9b2933dcae10fa397c763 250 PIRSF PIRSF039085 1 250 3.1E-124 T 23-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 DC74_RS26625 3aa80f45e1b9b2933dcae10fa397c763 250 SMART SM00382 26 223 5.5E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS26625 3aa80f45e1b9b2933dcae10fa397c763 250 Gene3D G3DSA:3.40.50.300 1 247 1.6E-83 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26625 3aa80f45e1b9b2933dcae10fa397c763 250 PANTHER PTHR24220 3 250 2.7E-138 T 23-04-2016 DC74_RS05910 d61003ed4e8d6bd22cfec35de76845d6 107 Gene3D G3DSA:1.10.10.10 14 98 1.7E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05910 d61003ed4e8d6bd22cfec35de76845d6 107 PANTHER PTHR33154 7 107 5.6E-36 T 23-04-2016 DC74_RS05910 d61003ed4e8d6bd22cfec35de76845d6 107 PANTHER PTHR33154:SF2 7 107 5.6E-36 T 23-04-2016 DC74_RS05910 d61003ed4e8d6bd22cfec35de76845d6 107 SUPERFAMILY SSF46785 11 97 1.07E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05910 d61003ed4e8d6bd22cfec35de76845d6 107 Pfam PF12840 Helix-turn-helix domain 17 76 4.1E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05910 d61003ed4e8d6bd22cfec35de76845d6 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 1.4E-6 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS05910 d61003ed4e8d6bd22cfec35de76845d6 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 1.4E-6 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS05910 d61003ed4e8d6bd22cfec35de76845d6 107 SMART SM00418 17 97 5.3E-11 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 Gene3D G3DSA:2.40.50.140 200 337 1.8E-14 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 Gene3D G3DSA:3.30.1490.70 156 196 8.9E-12 T 23-04-2016 DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 Gene3D G3DSA:3.30.1490.70 3 31 8.9E-12 T 23-04-2016 DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 Pfam PF01068 ATP dependent DNA ligase domain 11 197 4.3E-36 T 23-04-2016 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 Reactome: REACT_216 DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 27 35 - T 23-04-2016 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 Reactome: REACT_216 DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 SUPERFAMILY SSF56091 6 197 4.32E-39 T 23-04-2016 DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 Gene3D G3DSA:3.30.470.30 32 148 7.0E-26 T 23-04-2016 DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 Pfam PF04679 ATP dependent DNA ligase C terminal region 215 331 1.3E-14 T 23-04-2016 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 PANTHER PTHR10459 290 349 1.0E-142 T 23-04-2016 DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 PANTHER PTHR10459 1 262 1.0E-142 T 23-04-2016 DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 SUPERFAMILY SSF50249 200 340 5.48E-14 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 PANTHER PTHR10459:SF51 290 349 1.0E-142 T 23-04-2016 DC74_RS35970 936266f9d160d4d1c58cf006e5486268 355 PANTHER PTHR10459:SF51 1 262 1.0E-142 T 23-04-2016 DC74_RS01030 af854ccb7e73b81e5f76b1507f62e6f7 170 SMART SM00530 12 78 7.6E-4 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS01030 af854ccb7e73b81e5f76b1507f62e6f7 170 SUPERFAMILY SSF47413 23 84 2.82E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS01030 af854ccb7e73b81e5f76b1507f62e6f7 170 Pfam PF01381 Helix-turn-helix 33 78 2.0E-7 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS01030 af854ccb7e73b81e5f76b1507f62e6f7 170 Gene3D G3DSA:1.10.260.40 32 83 4.6E-10 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS27835 818937cdc1fb655a786f7d12c69001fc 197 Gene3D G3DSA:3.40.50.300 15 189 3.9E-15 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27835 818937cdc1fb655a786f7d12c69001fc 197 PANTHER PTHR11711:SF117 22 197 1.4E-57 T 23-04-2016 DC74_RS27835 818937cdc1fb655a786f7d12c69001fc 197 Pfam PF03029 Conserved hypothetical ATP binding protein 25 192 3.9E-28 T 23-04-2016 IPR004130 GPN-loop GTPase DC74_RS27835 818937cdc1fb655a786f7d12c69001fc 197 SUPERFAMILY SSF52540 20 191 2.53E-22 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27835 818937cdc1fb655a786f7d12c69001fc 197 PANTHER PTHR11711 22 197 1.4E-57 T 23-04-2016 DC74_RS20490 53982db9d0d5bfed63d97002ef6c9876 377 PANTHER PTHR10909:SF302 1 358 2.1E-49 T 23-04-2016 DC74_RS20490 53982db9d0d5bfed63d97002ef6c9876 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 8.0E-14 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS20490 53982db9d0d5bfed63d97002ef6c9876 377 SUPERFAMILY SSF56645 2 221 1.96E-36 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS20490 53982db9d0d5bfed63d97002ef6c9876 377 Gene3D G3DSA:1.10.540.10 3 120 1.8E-15 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS20490 53982db9d0d5bfed63d97002ef6c9876 377 SUPERFAMILY SSF47203 233 371 4.67E-28 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS20490 53982db9d0d5bfed63d97002ef6c9876 377 Gene3D G3DSA:2.40.110.10 131 212 7.7E-13 T 23-04-2016 DC74_RS20490 53982db9d0d5bfed63d97002ef6c9876 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 364 1.9E-20 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS20490 53982db9d0d5bfed63d97002ef6c9876 377 PANTHER PTHR10909 1 358 2.1E-49 T 23-04-2016 DC74_RS20490 53982db9d0d5bfed63d97002ef6c9876 377 Gene3D G3DSA:1.20.140.10 213 371 3.3E-28 T 23-04-2016 DC74_RS37870 7933ba85a17f94e1f38370bf814a9fb9 206 Pfam PF01300 Telomere recombination 23 198 1.0E-41 T 23-04-2016 IPR006070 YrdC-like domain GO:0003725 DC74_RS37870 7933ba85a17f94e1f38370bf814a9fb9 206 PANTHER PTHR17490 1 205 3.0E-84 T 23-04-2016 DC74_RS37870 7933ba85a17f94e1f38370bf814a9fb9 206 Gene3D G3DSA:3.90.870.10 2 204 1.4E-59 T 23-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain DC74_RS37870 7933ba85a17f94e1f38370bf814a9fb9 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 4.7E-52 T 23-04-2016 IPR006070 YrdC-like domain GO:0003725 DC74_RS37870 7933ba85a17f94e1f38370bf814a9fb9 206 SUPERFAMILY SSF55821 1 204 4.58E-58 T 23-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain DC74_RS37870 7933ba85a17f94e1f38370bf814a9fb9 206 PANTHER PTHR17490:SF7 1 205 3.0E-84 T 23-04-2016 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 Pfam PF00931 NB-ARC domain 321 562 2.1E-9 T 23-04-2016 IPR002182 NB-ARC GO:0043531 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 SUPERFAMILY SSF52540 308 565 9.32E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 PANTHER PTHR22845:SF4 143 260 4.0E-63 T 23-04-2016 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 Gene3D G3DSA:3.40.50.300 317 431 7.0E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 SMART SM01043 101 243 4.5E-41 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 Gene3D G3DSA:1.25.40.10 155 222 1.8E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 SUPERFAMILY SSF46894 3 81 1.64E-11 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 PRINTS PR00364 Disease resistance protein signature 417 431 4.1E-7 T 23-04-2016 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 PRINTS PR00364 Disease resistance protein signature 339 354 4.1E-7 T 23-04-2016 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 PRINTS PR00364 Disease resistance protein signature 505 519 4.1E-7 T 23-04-2016 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 PANTHER PTHR22845 299 634 4.0E-63 T 23-04-2016 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 PANTHER PTHR22845 143 260 4.0E-63 T 23-04-2016 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 Pfam PF03704 Bacterial transcriptional activator domain 101 243 1.4E-38 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 SMART SM00862 15 94 8.0E-8 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 78 2.1E-8 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 SUPERFAMILY SSF48452 98 261 1.19E-29 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 Gene3D G3DSA:1.10.10.10 11 94 5.7E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20285 ac98bcb118f0cf29754b1a6d07e596e2 659 PANTHER PTHR22845:SF4 299 634 4.0E-63 T 23-04-2016 DC74_RS20450 ebcf297489fbce58d9e9ba3019914bee 221 SUPERFAMILY SSF75217 58 215 1.64E-34 T 23-04-2016 IPR029028 Alpha/beta knot methyltransferases DC74_RS20450 ebcf297489fbce58d9e9ba3019914bee 221 Pfam PF00588 SpoU rRNA Methylase family 73 209 7.8E-22 T 23-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 DC74_RS20450 ebcf297489fbce58d9e9ba3019914bee 221 PANTHER PTHR12029 59 211 1.3E-18 T 23-04-2016 DC74_RS20450 ebcf297489fbce58d9e9ba3019914bee 221 Gene3D G3DSA:3.40.1280.10 55 216 8.3E-39 T 23-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 Pfam PF00672 HAMP domain 108 174 1.6E-13 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 SUPERFAMILY SSF158472 125 175 3.53E-7 T 23-04-2016 DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 Gene3D G3DSA:3.30.565.10 247 407 3.9E-33 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 SMART SM00304 125 178 2.7E-12 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 Gene3D G3DSA:1.10.287.130 172 239 1.8E-8 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 SMART SM00387 297 409 3.4E-30 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 SMART SM00388 179 244 5.3E-5 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 SUPERFAMILY SSF55874 238 409 3.54E-32 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 Pfam PF00512 His Kinase A (phospho-acceptor) domain 180 243 1.8E-6 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 387 1.0E-9 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 362 1.0E-9 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 348 1.0E-9 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 406 1.6E-17 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 PANTHER PTHR24423 120 411 9.2E-57 T 23-04-2016 DC74_RS06055 d09e692166f7c677b8403e02ac6af12e 413 SUPERFAMILY SSF47384 162 242 6.87E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 SUPERFAMILY SSF52096 35 218 4.97E-61 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 27 218 39.345 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 PANTHER PTHR10381 18 218 2.2E-136 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 Pfam PF00574 Clp protease 37 217 2.0E-75 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 PRINTS PR00127 Clp protease catalytic subunit P signature 135 154 1.3E-41 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 PRINTS PR00127 Clp protease catalytic subunit P signature 83 103 1.3E-41 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 PRINTS PR00127 Clp protease catalytic subunit P signature 114 131 1.3E-41 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 PRINTS PR00127 Clp protease catalytic subunit P signature 43 58 1.3E-41 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 PRINTS PR00127 Clp protease catalytic subunit P signature 193 212 1.3E-41 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 136 149 - T 23-04-2016 IPR033135 ClpP, histidine active site DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 Gene3D G3DSA:3.90.226.10 28 218 2.1E-73 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 PANTHER PTHR10381:SF7 18 218 2.2E-136 T 23-04-2016 DC74_RS15320 1253357742a411ad23ef3cf54aafb5ba 224 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 114 125 - T 23-04-2016 IPR018215 ClpP, Ser active site DC74_RS17135 715f5c62fd98d370a994d1d62a75765e 390 SUPERFAMILY SSF51556 293 378 6.51E-106 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS17135 715f5c62fd98d370a994d1d62a75765e 390 SUPERFAMILY SSF51556 5 253 6.51E-106 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS17135 715f5c62fd98d370a994d1d62a75765e 390 PANTHER PTHR10443:SF26 8 253 5.6E-193 T 23-04-2016 DC74_RS17135 715f5c62fd98d370a994d1d62a75765e 390 PANTHER PTHR10443 293 381 5.6E-193 T 23-04-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 DC74_RS17135 715f5c62fd98d370a994d1d62a75765e 390 Gene3D G3DSA:3.20.20.140 5 381 1.3E-149 T 23-04-2016 DC74_RS17135 715f5c62fd98d370a994d1d62a75765e 390 PANTHER PTHR10443 8 253 5.6E-193 T 23-04-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 DC74_RS17135 715f5c62fd98d370a994d1d62a75765e 390 PANTHER PTHR10443:SF26 293 381 5.6E-193 T 23-04-2016 DC74_RS17135 715f5c62fd98d370a994d1d62a75765e 390 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 11 370 4.0E-120 T 23-04-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 DC74_RS06975 7be1572279c049adcac2cc78a920a989 346 Gene3D G3DSA:3.40.50.720 172 286 2.8E-23 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06975 7be1572279c049adcac2cc78a920a989 346 PANTHER PTHR11695:SF498 16 338 1.1E-115 T 23-04-2016 DC74_RS06975 7be1572279c049adcac2cc78a920a989 346 Gene3D G3DSA:3.90.180.10 4 171 6.1E-56 T 23-04-2016 IPR011032 GroES-like DC74_RS06975 7be1572279c049adcac2cc78a920a989 346 SUPERFAMILY SSF51735 143 306 1.45E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06975 7be1572279c049adcac2cc78a920a989 346 SUPERFAMILY SSF50129 1 173 1.13E-46 T 23-04-2016 IPR011032 GroES-like DC74_RS06975 7be1572279c049adcac2cc78a920a989 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 135 1.3E-27 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS06975 7be1572279c049adcac2cc78a920a989 346 PANTHER PTHR11695 16 338 1.1E-115 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS06975 7be1572279c049adcac2cc78a920a989 346 Pfam PF00107 Zinc-binding dehydrogenase 178 302 1.4E-20 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS06975 7be1572279c049adcac2cc78a920a989 346 SMART SM00829 13 337 9.7E-6 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS05835 047046659b98c8139253f8838c5a4045 718 SUPERFAMILY SSF52540 478 717 2.84E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05835 047046659b98c8139253f8838c5a4045 718 SUPERFAMILY SSF52540 190 270 2.84E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05835 047046659b98c8139253f8838c5a4045 718 PANTHER PTHR11070:SF25 482 623 1.0E-81 T 23-04-2016 DC74_RS05835 047046659b98c8139253f8838c5a4045 718 PANTHER PTHR11070:SF25 95 362 1.0E-81 T 23-04-2016 DC74_RS05835 047046659b98c8139253f8838c5a4045 718 PANTHER PTHR11070 482 623 1.0E-81 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS05835 047046659b98c8139253f8838c5a4045 718 PANTHER PTHR11070 95 362 1.0E-81 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS05835 047046659b98c8139253f8838c5a4045 718 Pfam PF01443 Viral (Superfamily 1) RNA helicase 529 716 8.1E-5 T 23-04-2016 IPR027351 (+) RNA virus helicase core domain GO:0005524 DC74_RS05835 047046659b98c8139253f8838c5a4045 718 Gene3D G3DSA:3.40.50.300 507 602 3.2E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05835 047046659b98c8139253f8838c5a4045 718 Gene3D G3DSA:3.40.50.300 191 300 3.2E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05835 047046659b98c8139253f8838c5a4045 718 Pfam PF13245 Part of AAA domain 203 280 2.1E-12 T 23-04-2016 DC74_RS05835 047046659b98c8139253f8838c5a4045 718 Gene3D G3DSA:3.40.50.300 655 716 4.8E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09210 ee74d26b00ec0eb1332188579a719e54 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 156 28.194 T 23-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS09210 ee74d26b00ec0eb1332188579a719e54 161 PANTHER PTHR21058 16 161 1.2E-58 T 23-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS09210 ee74d26b00ec0eb1332188579a719e54 161 Gene3D G3DSA:3.40.50.960 13 156 3.6E-56 T 23-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS09210 ee74d26b00ec0eb1332188579a719e54 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 152 3.0E-50 T 23-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS09210 ee74d26b00ec0eb1332188579a719e54 161 SUPERFAMILY SSF52121 12 156 1.31E-53 T 23-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS09210 ee74d26b00ec0eb1332188579a719e54 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 151 5.9E-42 T 23-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS05815 4a22e7d6e96f96cddb84224bcf2f1415 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 119 139 2.5E-6 T 23-04-2016 DC74_RS05815 4a22e7d6e96f96cddb84224bcf2f1415 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 410 429 2.5E-6 T 23-04-2016 DC74_RS05815 4a22e7d6e96f96cddb84224bcf2f1415 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 2.5E-6 T 23-04-2016 DC74_RS05815 4a22e7d6e96f96cddb84224bcf2f1415 486 SUPERFAMILY SSF103473 8 208 1.7E-55 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05815 4a22e7d6e96f96cddb84224bcf2f1415 486 SUPERFAMILY SSF103473 260 463 1.7E-55 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05815 4a22e7d6e96f96cddb84224bcf2f1415 486 PANTHER PTHR23501 7 478 1.3E-82 T 23-04-2016 DC74_RS05815 4a22e7d6e96f96cddb84224bcf2f1415 486 Pfam PF07690 Major Facilitator Superfamily 29 419 1.4E-40 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS05815 4a22e7d6e96f96cddb84224bcf2f1415 486 Gene3D G3DSA:1.20.1250.20 9 205 1.7E-30 T 23-04-2016 DC74_RS05815 4a22e7d6e96f96cddb84224bcf2f1415 486 Gene3D G3DSA:1.20.1250.20 274 466 1.1E-13 T 23-04-2016 DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 PANTHER PTHR22683:SF1 8 690 7.8E-293 T 23-04-2016 DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 PANTHER PTHR22683:SF1 895 1180 7.8E-293 T 23-04-2016 DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 SUPERFAMILY SSF52540 429 656 1.15E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 688 5.5E-262 T 23-04-2016 IPR023836 EccCa-like, Actinobacteria DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 750 1320 8.2E-231 T 23-04-2016 IPR023837 EccCb-like, Actinobacteria DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 PANTHER PTHR22683 1230 1321 7.8E-293 T 23-04-2016 DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 PANTHER PTHR22683:SF1 1230 1321 7.8E-293 T 23-04-2016 DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 PANTHER PTHR22683 8 690 7.8E-293 T 23-04-2016 DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 PANTHER PTHR22683 895 1180 7.8E-293 T 23-04-2016 DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 SUPERFAMILY SSF52540 1084 1255 7.73E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 SUPERFAMILY SSF52540 805 1025 1.28E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 SMART SM00382 831 1003 0.014 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 SMART SM00382 465 644 0.37 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 SMART SM00382 1117 1319 1.6 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 Gene3D G3DSA:3.40.50.300 437 657 6.5E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 Gene3D G3DSA:3.40.50.300 827 1012 3.0E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 Pfam PF01580 FtsK/SpoIIIE family 809 1043 1.3E-51 T 23-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 DC74_RS19135 af1005fad6b90308aaa6749e02f209fa 1325 Pfam PF01580 FtsK/SpoIIIE family 435 563 1.0E-24 T 23-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 DC74_RS00560 96ec4ac91c6083418537b920f0f26703 450 SUPERFAMILY SSF54909 14 447 9.83E-125 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS00560 96ec4ac91c6083418537b920f0f26703 450 Pfam PF04261 Dyp-type peroxidase family 231 382 2.3E-5 T 23-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- DC74_RS00560 96ec4ac91c6083418537b920f0f26703 450 PANTHER PTHR30521:SF2 63 449 2.7E-87 T 23-04-2016 DC74_RS00560 96ec4ac91c6083418537b920f0f26703 450 PANTHER PTHR30521 63 449 2.7E-87 T 23-04-2016 DC74_RS00560 96ec4ac91c6083418537b920f0f26703 450 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 28 441 5.8E-33 T 23-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- DC74_RS04855 8714dd37ef12014fd61118541bea735f 208 PANTHER PTHR14119 1 207 5.8E-52 T 23-04-2016 DC74_RS04855 8714dd37ef12014fd61118541bea735f 208 Pfam PF00857 Isochorismatase family 17 167 3.6E-22 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS04855 8714dd37ef12014fd61118541bea735f 208 Gene3D G3DSA:3.40.50.850 10 191 1.9E-33 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS04855 8714dd37ef12014fd61118541bea735f 208 SUPERFAMILY SSF52499 7 189 4.84E-39 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS04855 8714dd37ef12014fd61118541bea735f 208 PANTHER PTHR14119:SF11 1 207 5.8E-52 T 23-04-2016 DC74_RS15095 701f66770af3cddebe32914dd8057ca9 257 PRINTS PR01543 Arylamine N-acetyltransferase signature 46 69 1.6E-9 T 23-04-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 DC74_RS15095 701f66770af3cddebe32914dd8057ca9 257 PRINTS PR01543 Arylamine N-acetyltransferase signature 22 45 1.6E-9 T 23-04-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 DC74_RS15095 701f66770af3cddebe32914dd8057ca9 257 PRINTS PR01543 Arylamine N-acetyltransferase signature 70 92 1.6E-9 T 23-04-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 DC74_RS15095 701f66770af3cddebe32914dd8057ca9 257 Pfam PF00797 N-acetyltransferase 24 251 3.5E-64 T 23-04-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 DC74_RS15095 701f66770af3cddebe32914dd8057ca9 257 PANTHER PTHR11786 7 251 3.6E-56 T 23-04-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 DC74_RS15095 701f66770af3cddebe32914dd8057ca9 257 SUPERFAMILY SSF54001 2 251 1.94E-65 T 23-04-2016 DC74_RS15095 701f66770af3cddebe32914dd8057ca9 257 Gene3D G3DSA:3.30.2140.10 3 86 6.1E-50 T 23-04-2016 DC74_RS15095 701f66770af3cddebe32914dd8057ca9 257 Gene3D G3DSA:3.30.2140.10 178 253 6.1E-50 T 23-04-2016 DC74_RS15095 701f66770af3cddebe32914dd8057ca9 257 PANTHER PTHR11786:SF0 7 251 3.6E-56 T 23-04-2016 DC74_RS13030 95f225457b8b335bc72fda4dc693e0df 348 Gene3D G3DSA:3.40.50.10210 75 335 5.8E-87 T 23-04-2016 DC74_RS13030 95f225457b8b335bc72fda4dc693e0df 348 PANTHER PTHR21712:SF33 13 340 7.2E-168 T 23-04-2016 DC74_RS13030 95f225457b8b335bc72fda4dc693e0df 348 Gene3D G3DSA:1.10.1610.10 6 74 4.4E-18 T 23-04-2016 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 DC74_RS13030 95f225457b8b335bc72fda4dc693e0df 348 Pfam PF02277 Phosphoribosyltransferase 13 343 3.5E-101 T 23-04-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 DC74_RS13030 95f225457b8b335bc72fda4dc693e0df 348 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 17 344 1.1E-98 T 23-04-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 DC74_RS13030 95f225457b8b335bc72fda4dc693e0df 348 SUPERFAMILY SSF52733 8 343 2.62E-87 T 23-04-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 DC74_RS13030 95f225457b8b335bc72fda4dc693e0df 348 PANTHER PTHR21712 13 340 7.2E-168 T 23-04-2016 DC74_RS20075 07cbcbe1be20a272b53f401e4593f7c4 397 SUPERFAMILY SSF47413 1 45 1.13E-5 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS20075 07cbcbe1be20a272b53f401e4593f7c4 397 Gene3D G3DSA:1.25.40.10 74 172 3.6E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20075 07cbcbe1be20a272b53f401e4593f7c4 397 Pfam PF01381 Helix-turn-helix 7 44 2.6E-5 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS20075 07cbcbe1be20a272b53f401e4593f7c4 397 Gene3D G3DSA:1.10.260.40 1 60 2.0E-5 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 PANTHER PTHR30363 6 259 1.4E-62 T 23-04-2016 DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 SUPERFAMILY SSF100950 79 237 1.02E-23 T 23-04-2016 DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 Gene3D G3DSA:3.40.50.1360 79 218 8.7E-8 T 23-04-2016 DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 28 42 8.8E-5 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 42 60 8.8E-5 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 SUPERFAMILY SSF46785 8 72 9.62E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 SMART SM01134 77 237 2.8E-58 T 23-04-2016 DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 SMART SM00420 10 62 1.8E-9 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 ProSitePatterns PS00894 DeoR-type HTH domain signature. 10 44 - T 23-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 Gene3D G3DSA:1.10.10.10 9 59 7.6E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 Pfam PF00455 DeoR C terminal sensor domain 80 235 8.9E-46 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 PANTHER PTHR30363:SF1 6 259 1.4E-62 T 23-04-2016 DC74_RS33815 1c346026744f43efeb5bd6c6a71239e8 260 Pfam PF08220 DeoR-like helix-turn-helix domain 10 61 9.8E-12 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 Gene3D G3DSA:3.10.28.10 451 507 1.5E-4 T 23-04-2016 IPR027434 Homing endonuclease GO:0004519 DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 SUPERFAMILY SSF52540 187 303 2.66E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 Pfam PF00270 DEAD/DEAH box helicase 573 712 2.3E-10 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 PANTHER PTHR24031 813 908 3.2E-95 T 23-04-2016 DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 PANTHER PTHR24031 572 779 3.2E-95 T 23-04-2016 DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 PANTHER PTHR24031 932 982 3.2E-95 T 23-04-2016 DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 SUPERFAMILY SSF52540 810 904 4.87E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 SUPERFAMILY SSF52540 586 776 4.87E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 SUPERFAMILY SSF51294 515 571 7.85E-9 T 23-04-2016 IPR028992 Hedgehog/Intein (Hint) domain DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 SUPERFAMILY SSF51294 458 474 7.85E-9 T 23-04-2016 IPR028992 Hedgehog/Intein (Hint) domain DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 SUPERFAMILY SSF51294 306 404 7.85E-9 T 23-04-2016 IPR028992 Hedgehog/Intein (Hint) domain DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 Gene3D G3DSA:3.40.50.300 258 303 9.8E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 Gene3D G3DSA:3.40.50.300 573 731 1.9E-40 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 Gene3D G3DSA:3.40.50.300 811 943 3.1E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 Gene3D G3DSA:3.40.50.300 732 777 3.1E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 Gene3D G3DSA:2.170.16.10 306 405 1.2E-8 T 23-04-2016 IPR028992 Hedgehog/Intein (Hint) domain DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 Gene3D G3DSA:2.170.16.10 522 572 1.2E-8 T 23-04-2016 IPR028992 Hedgehog/Intein (Hint) domain DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 SMART SM00487 266 748 9.9E-13 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 PANTHER PTHR24031:SF249 813 908 3.2E-95 T 23-04-2016 DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 PANTHER PTHR24031:SF249 572 779 3.2E-95 T 23-04-2016 DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 PANTHER PTHR24031:SF249 932 982 3.2E-95 T 23-04-2016 DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 Gene3D G3DSA:2.40.50.140 48 143 2.3E-16 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 SUPERFAMILY SSF50249 14 181 8.57E-29 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 Pfam PF17191 RecG wedge domain 15 175 3.9E-10 T 23-04-2016 IPR033454 RecG, wedge domain DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 Pfam PF00271 Helicase conserved C-terminal domain 818 894 4.5E-19 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS27980 d11b85a67a8f695eba6120b4dd587914 1007 SMART SM00490 810 895 7.3E-24 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS36975 669ea3781d0ffcfb26a53d6e4d60659d 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS36975 669ea3781d0ffcfb26a53d6e4d60659d 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS36975 669ea3781d0ffcfb26a53d6e4d60659d 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS36975 669ea3781d0ffcfb26a53d6e4d60659d 283 Gene3D G3DSA:3.40.190.10 90 173 7.1E-13 T 23-04-2016 DC74_RS36975 669ea3781d0ffcfb26a53d6e4d60659d 283 Gene3D G3DSA:1.10.10.10 1 84 1.0E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36975 669ea3781d0ffcfb26a53d6e4d60659d 283 Gene3D G3DSA:3.40.190.10 174 225 1.3E-4 T 23-04-2016 DC74_RS36975 669ea3781d0ffcfb26a53d6e4d60659d 283 PANTHER PTHR30346 1 281 5.3E-76 T 23-04-2016 DC74_RS36975 669ea3781d0ffcfb26a53d6e4d60659d 283 SUPERFAMILY SSF46785 1 84 6.85E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36975 669ea3781d0ffcfb26a53d6e4d60659d 283 SUPERFAMILY SSF53850 90 282 6.05E-19 T 23-04-2016 DC74_RS36975 669ea3781d0ffcfb26a53d6e4d60659d 283 PANTHER PTHR30346:SF0 1 281 5.3E-76 T 23-04-2016 DC74_RS36975 669ea3781d0ffcfb26a53d6e4d60659d 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 8.0E-22 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS36975 669ea3781d0ffcfb26a53d6e4d60659d 283 Pfam PF03466 LysR substrate binding domain 89 279 4.1E-22 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS15240 b543633e3c54d4f8c1ac852ba029964b 640 PANTHER PTHR11918:SF77 38 195 6.7E-254 T 23-04-2016 DC74_RS15240 b543633e3c54d4f8c1ac852ba029964b 640 PANTHER PTHR11918:SF77 229 617 6.7E-254 T 23-04-2016 DC74_RS15240 b543633e3c54d4f8c1ac852ba029964b 640 Gene3D G3DSA:3.80.30.20 262 491 3.0E-44 T 23-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe DC74_RS15240 b543633e3c54d4f8c1ac852ba029964b 640 SUPERFAMILY SSF102114 231 634 8.24E-52 T 23-04-2016 DC74_RS15240 b543633e3c54d4f8c1ac852ba029964b 640 SMART SM00729 263 486 8.8E-30 T 23-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 DC74_RS15240 b543633e3c54d4f8c1ac852ba029964b 640 Pfam PF04055 Radical SAM superfamily 267 432 9.5E-16 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS15240 b543633e3c54d4f8c1ac852ba029964b 640 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 11 619 9.9E-212 T 23-04-2016 IPR023862 Conserved hypothetical protein CHP03960, radical SAM DC74_RS15240 b543633e3c54d4f8c1ac852ba029964b 640 PANTHER PTHR11918 38 195 6.7E-254 T 23-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein DC74_RS15240 b543633e3c54d4f8c1ac852ba029964b 640 PANTHER PTHR11918 229 617 6.7E-254 T 23-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 Gene3D G3DSA:3.40.50.300 52 271 2.6E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 SMART SM00487 82 282 8.2E-50 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 Pfam PF00271 Helicase conserved C-terminal domain 299 397 1.5E-21 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 Pfam PF00270 DEAD/DEAH box helicase 87 254 8.5E-45 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 SUPERFAMILY SSF52540 134 418 1.86E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 Gene3D G3DSA:3.40.50.300 272 420 1.3E-40 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 SMART SM00490 316 397 2.8E-27 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 PANTHER PTHR24031 537 552 1.4E-279 T 23-04-2016 DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 PANTHER PTHR24031 64 477 1.4E-279 T 23-04-2016 DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 PANTHER PTHR24031 31 38 1.4E-279 T 23-04-2016 DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 PANTHER PTHR24031 603 739 1.4E-279 T 23-04-2016 DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 PANTHER PTHR24031:SF334 537 552 1.4E-279 T 23-04-2016 DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 PANTHER PTHR24031:SF334 64 477 1.4E-279 T 23-04-2016 DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 PANTHER PTHR24031:SF334 31 38 1.4E-279 T 23-04-2016 DC74_RS19610 f71cbe0d6c1a18742f6ba798932d2347 757 PANTHER PTHR24031:SF334 603 739 1.4E-279 T 23-04-2016 DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 Hamap MF_00173 Arginine repressor [argR]. 1 179 57.305 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 TIGRFAM TIGR01529 argR_whole: arginine repressor 22 175 3.0E-44 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 PRINTS PR01467 Bacterial arginine repressor signature 38 51 1.7E-26 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 PRINTS PR01467 Bacterial arginine repressor signature 54 69 1.7E-26 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 PRINTS PR01467 Bacterial arginine repressor signature 115 128 1.7E-26 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 PRINTS PR01467 Bacterial arginine repressor signature 145 160 1.7E-26 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 Gene3D G3DSA:1.10.10.10 16 88 2.0E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 Gene3D G3DSA:3.30.1360.40 100 175 1.4E-28 T 23-04-2016 IPR024946 Arginine repressor C-terminal-like domain DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 SUPERFAMILY SSF46785 18 85 1.17E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 119 154 2.0E-13 T 23-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 Pfam PF02863 Arginine repressor, C-terminal domain 109 172 8.0E-24 T 23-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 PANTHER PTHR34471 15 180 3.3E-60 T 23-04-2016 DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 Pfam PF01316 Arginine repressor, DNA binding domain 19 86 7.8E-25 T 23-04-2016 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 UniPathway: UPA00068 DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 SUPERFAMILY SSF55252 109 174 6.54E-19 T 23-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 DC74_RS09895 bdd37f1ed50cce3b28c71c831b04eda3 180 PANTHER PTHR34471:SF1 15 180 3.3E-60 T 23-04-2016 DC74_RS04070 14f61df212352e9520782f9ff5028ea0 250 Gene3D G3DSA:3.40.50.150 19 220 5.5E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS04070 14f61df212352e9520782f9ff5028ea0 250 SUPERFAMILY SSF53335 15 228 4.03E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS04070 14f61df212352e9520782f9ff5028ea0 250 Pfam PF13649 Methyltransferase domain 60 158 9.3E-21 T 23-04-2016 DC74_RS04070 14f61df212352e9520782f9ff5028ea0 250 PANTHER PTHR10108:SF705 192 220 3.0E-25 T 23-04-2016 DC74_RS04070 14f61df212352e9520782f9ff5028ea0 250 PANTHER PTHR10108:SF705 19 174 3.0E-25 T 23-04-2016 DC74_RS04070 14f61df212352e9520782f9ff5028ea0 250 PANTHER PTHR10108 192 220 3.0E-25 T 23-04-2016 DC74_RS04070 14f61df212352e9520782f9ff5028ea0 250 PANTHER PTHR10108 19 174 3.0E-25 T 23-04-2016 DC74_RS14075 b9bc066218b002980b6a3460fb36738b 194 PANTHER PTHR30055 2 194 3.3E-20 T 23-04-2016 DC74_RS14075 b9bc066218b002980b6a3460fb36738b 194 Pfam PF13977 Bacterial transcriptional repressor 79 173 4.0E-9 T 23-04-2016 DC74_RS14075 b9bc066218b002980b6a3460fb36738b 194 SUPERFAMILY SSF48498 78 180 3.22E-16 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS14075 b9bc066218b002980b6a3460fb36738b 194 Gene3D G3DSA:1.10.357.10 2 180 8.5E-35 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS14075 b9bc066218b002980b6a3460fb36738b 194 SUPERFAMILY SSF46689 2 67 1.7E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS14075 b9bc066218b002980b6a3460fb36738b 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 53 5.3E-16 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS14075 b9bc066218b002980b6a3460fb36738b 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.1E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS14075 b9bc066218b002980b6a3460fb36738b 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.1E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10010 ca49efd4f35d75c9f3970d6e9b6c5502 322 SUPERFAMILY SSF51679 1 296 2.02E-34 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10010 ca49efd4f35d75c9f3970d6e9b6c5502 322 Pfam PF00296 Luciferase-like monooxygenase 32 289 1.1E-24 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10010 ca49efd4f35d75c9f3970d6e9b6c5502 322 Gene3D G3DSA:3.20.20.30 1 296 3.8E-33 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS26905 6212e3ad054445a7e23a01ea747f451f 446 PANTHER PTHR22926 2 248 8.9E-105 T 23-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS26905 6212e3ad054445a7e23a01ea747f451f 446 PANTHER PTHR22926 275 390 8.9E-105 T 23-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS26905 6212e3ad054445a7e23a01ea747f451f 446 Pfam PF00953 Glycosyl transferase family 4 82 241 1.8E-34 T 23-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS26905 6212e3ad054445a7e23a01ea747f451f 446 PANTHER PTHR22926:SF3 2 248 8.9E-105 T 23-04-2016 DC74_RS26905 6212e3ad054445a7e23a01ea747f451f 446 PANTHER PTHR22926:SF3 275 390 8.9E-105 T 23-04-2016 DC74_RS33485 74284630bca5610939ba139cba4c6c68 440 PANTHER PTHR23513 27 439 5.8E-112 T 23-04-2016 DC74_RS33485 74284630bca5610939ba139cba4c6c68 440 PANTHER PTHR23513:SF9 27 439 5.8E-112 T 23-04-2016 DC74_RS33485 74284630bca5610939ba139cba4c6c68 440 SUPERFAMILY SSF103473 47 429 8.37E-45 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS33485 74284630bca5610939ba139cba4c6c68 440 Pfam PF05977 Transmembrane secretion effector 37 422 1.5E-47 T 23-04-2016 IPR010290 Transmembrane secretion effector DC74_RS33485 74284630bca5610939ba139cba4c6c68 440 Gene3D G3DSA:1.20.1250.20 268 425 3.0E-12 T 23-04-2016 DC74_RS33485 74284630bca5610939ba139cba4c6c68 440 Gene3D G3DSA:1.20.1250.20 48 228 1.6E-22 T 23-04-2016 DC74_RS12340 222a19c7b8f559a6fb9fa3c061ba3fff 299 Gene3D G3DSA:3.40.190.10 90 178 1.3E-17 T 23-04-2016 DC74_RS12340 222a19c7b8f559a6fb9fa3c061ba3fff 299 Gene3D G3DSA:1.10.10.10 1 85 9.5E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS12340 222a19c7b8f559a6fb9fa3c061ba3fff 299 Pfam PF03466 LysR substrate binding domain 87 294 1.0E-45 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS12340 222a19c7b8f559a6fb9fa3c061ba3fff 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.38E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS12340 222a19c7b8f559a6fb9fa3c061ba3fff 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.38E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS12340 222a19c7b8f559a6fb9fa3c061ba3fff 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.38E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS12340 222a19c7b8f559a6fb9fa3c061ba3fff 299 SUPERFAMILY SSF53850 90 297 1.13E-42 T 23-04-2016 DC74_RS12340 222a19c7b8f559a6fb9fa3c061ba3fff 299 Gene3D G3DSA:3.40.190.10 179 267 8.6E-23 T 23-04-2016 DC74_RS12340 222a19c7b8f559a6fb9fa3c061ba3fff 299 PANTHER PTHR30346 1 296 2.0E-88 T 23-04-2016 DC74_RS12340 222a19c7b8f559a6fb9fa3c061ba3fff 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-22 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS12340 222a19c7b8f559a6fb9fa3c061ba3fff 299 PANTHER PTHR30346:SF15 1 296 2.0E-88 T 23-04-2016 DC74_RS12340 222a19c7b8f559a6fb9fa3c061ba3fff 299 SUPERFAMILY SSF46785 1 110 2.55E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35685 1b194eb77de1ff2a87059207fee71c54 412 Pfam PF08353 Domain of unknown function (DUF1727) 304 403 6.5E-22 T 23-04-2016 IPR013564 Domain of unknown function DUF1727 DC74_RS35685 1b194eb77de1ff2a87059207fee71c54 412 Gene3D G3DSA:3.40.1190.10 47 280 3.1E-37 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS35685 1b194eb77de1ff2a87059207fee71c54 412 SUPERFAMILY SSF53623 47 280 2.59E-29 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS35685 1b194eb77de1ff2a87059207fee71c54 412 PANTHER PTHR23135:SF7 40 412 3.6E-144 T 23-04-2016 DC74_RS35685 1b194eb77de1ff2a87059207fee71c54 412 Pfam PF08245 Mur ligase middle domain 65 266 1.5E-12 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS35685 1b194eb77de1ff2a87059207fee71c54 412 PANTHER PTHR23135 40 412 3.6E-144 T 23-04-2016 DC74_RS31185 0d7e9c3c7559975c1b1afaba6741df83 413 Gene3D G3DSA:1.20.1250.20 25 192 3.3E-12 T 23-04-2016 DC74_RS31185 0d7e9c3c7559975c1b1afaba6741df83 413 PANTHER PTHR23513 3 405 1.4E-50 T 23-04-2016 DC74_RS31185 0d7e9c3c7559975c1b1afaba6741df83 413 SUPERFAMILY SSF103473 14 392 1.57E-23 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS31185 0d7e9c3c7559975c1b1afaba6741df83 413 Pfam PF05977 Transmembrane secretion effector 7 384 2.9E-15 T 23-04-2016 IPR010290 Transmembrane secretion effector DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 SUPERFAMILY SSF52317 159 378 8.87E-51 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 231 240 8.6E-11 T 23-04-2016 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 259 270 8.6E-11 T 23-04-2016 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 350 363 8.6E-11 T 23-04-2016 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 SUPERFAMILY SSF52021 12 145 9.15E-56 T 23-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 11 379 46.479 T 23-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 PRINTS PR00097 Anthranilate synthase component II signature 259 270 1.9E-5 T 23-04-2016 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 PRINTS PR00097 Anthranilate synthase component II signature 231 240 1.9E-5 T 23-04-2016 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 PRINTS PR00097 Anthranilate synthase component II signature 350 363 1.9E-5 T 23-04-2016 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 189 203 4.2E-30 T 23-04-2016 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 276 293 4.2E-30 T 23-04-2016 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 228 242 4.2E-30 T 23-04-2016 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 275 4.2E-30 T 23-04-2016 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 301 312 4.2E-30 T 23-04-2016 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 SMART SM01097 11 141 2.6E-87 T 23-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 13 376 3.4E-137 T 23-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 Gene3D G3DSA:3.50.30.20 12 145 1.1E-58 T 23-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 Gene3D G3DSA:3.40.50.880 162 377 8.9E-63 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 Pfam PF00117 Glutamine amidotransferase class-I 193 373 7.7E-38 T 23-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 13 139 3.2E-52 T 23-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 DC74_RS09440 52b52e2b8ba52a789cd1b3235f9c75ba 391 PANTHER PTHR11405 11 386 7.4E-205 T 23-04-2016 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 Gene3D G3DSA:2.160.10.10 986 1069 2.2E-8 T 23-04-2016 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 SUPERFAMILY SSF47336 520 589 2.59E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 SMART SM00823 Phosphopantetheine attachment site 525 592 0.0012 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 Pfam PF00501 AMP-binding enzyme 38 408 1.7E-64 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 Gene3D G3DSA:3.40.50.980 30 184 2.7E-34 T 23-04-2016 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 Gene3D G3DSA:2.30.38.10 326 397 3.7E-16 T 23-04-2016 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 PANTHER PTHR24095 32 495 7.3E-123 T 23-04-2016 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 Gene3D G3DSA:3.40.50.980 194 325 3.4E-35 T 23-04-2016 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 Pfam PF00550 Phosphopantetheine attachment site 527 588 2.3E-9 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 495 1.9E-5 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 SUPERFAMILY SSF56801 24 538 1.57E-112 T 23-04-2016 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 58 432 2.0E-99 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 783 811 - T 23-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 Gene3D G3DSA:3.30.300.30 403 505 1.9E-24 T 23-04-2016 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 SUPERFAMILY SSF51161 725 827 9.56E-16 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 SUPERFAMILY SSF51161 1189 1301 4.16E-16 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 611 1300 1.1E-198 T 23-04-2016 IPR012728 Non-ribosomal peptide synthetase, C-terminal DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 SUPERFAMILY SSF51161 918 1064 7.49E-14 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 Gene3D G3DSA:2.160.10.10 1202 1300 1.3E-18 T 23-04-2016 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 Gene3D G3DSA:2.160.10.10 727 837 1.1E-13 T 23-04-2016 DC74_RS34470 a9abe40a30a537ae94b139495097a5a1 1319 Gene3D G3DSA:1.10.1200.10 516 591 6.1E-17 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1806 1885 2.6E-14 T 23-04-2016 IPR022385 Rhs repeat-associated core GO:0097264 DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1353 1385 0.003 T 23-04-2016 IPR006530 YD repeat DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1313 1348 1.9E-5 T 23-04-2016 IPR006530 YD repeat DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 PANTHER PTHR11219:SF46 1514 1890 1.0E-36 T 23-04-2016 DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 PANTHER PTHR11219:SF46 1331 1399 1.0E-36 T 23-04-2016 DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 PANTHER PTHR11219 1514 1890 1.0E-36 T 23-04-2016 DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 PANTHER PTHR11219 1331 1399 1.0E-36 T 23-04-2016 DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 SMART SM00306 2040 2141 2.0E-9 T 23-04-2016 IPR003587 Hint domain N-terminal DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 Pfam PF05593 RHS Repeat 1311 1345 8.8E-6 T 23-04-2016 IPR031325 RHS repeat DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 Gene3D G3DSA:2.170.16.10 2042 2183 5.8E-25 T 23-04-2016 IPR028992 Hedgehog/Intein (Hint) domain DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 SUPERFAMILY SSF51294 2042 2184 1.83E-23 T 23-04-2016 IPR028992 Hedgehog/Intein (Hint) domain DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 Pfam PF07591 Pretoxin HINT domain 2057 2184 3.5E-19 T 23-04-2016 DC74_RS10640 d7eba2a1ffaacd252318514bb3f851f6 2289 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 2161 2184 9.4E-5 T 23-04-2016 IPR030934 Intein C-terminal splicing region DC74_RS09810 dad9f5cf1a64ff4fb791c9bc68ba7a9c 409 PANTHER PTHR14741:SF34 250 406 5.2E-20 T 23-04-2016 DC74_RS09810 dad9f5cf1a64ff4fb791c9bc68ba7a9c 409 Gene3D G3DSA:3.40.50.150 251 384 4.0E-15 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS09810 dad9f5cf1a64ff4fb791c9bc68ba7a9c 409 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 9 196 4.6E-37 T 23-04-2016 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 DC74_RS09810 dad9f5cf1a64ff4fb791c9bc68ba7a9c 409 SUPERFAMILY SSF53335 253 377 1.08E-15 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS09810 dad9f5cf1a64ff4fb791c9bc68ba7a9c 409 PIRSF PIRSF036428 1 406 4.2E-85 T 23-04-2016 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00148 DC74_RS09810 dad9f5cf1a64ff4fb791c9bc68ba7a9c 409 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 182 6.4E-19 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS09810 dad9f5cf1a64ff4fb791c9bc68ba7a9c 409 PANTHER PTHR14741 250 406 5.2E-20 T 23-04-2016 DC74_RS09810 dad9f5cf1a64ff4fb791c9bc68ba7a9c 409 Gene3D G3DSA:3.30.950.10 103 198 1.7E-18 T 23-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 DC74_RS09810 dad9f5cf1a64ff4fb791c9bc68ba7a9c 409 SUPERFAMILY SSF53790 8 197 1.57E-30 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS09810 dad9f5cf1a64ff4fb791c9bc68ba7a9c 409 Gene3D G3DSA:3.40.1010.10 5 102 8.4E-16 T 23-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 DC74_RS05290 e418a0bd024b3c39b49cbfdf05f78026 349 Gene3D G3DSA:3.40.50.1820 48 345 5.1E-52 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05290 e418a0bd024b3c39b49cbfdf05f78026 349 PANTHER PTHR10992:SF764 58 192 5.6E-59 T 23-04-2016 DC74_RS05290 e418a0bd024b3c39b49cbfdf05f78026 349 PANTHER PTHR10992:SF764 209 349 5.6E-59 T 23-04-2016 DC74_RS05290 e418a0bd024b3c39b49cbfdf05f78026 349 Pfam PF00561 alpha/beta hydrolase fold 79 331 6.4E-21 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS05290 e418a0bd024b3c39b49cbfdf05f78026 349 PRINTS PR00412 Epoxide hydrolase signature 152 165 1.1E-11 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS05290 e418a0bd024b3c39b49cbfdf05f78026 349 PRINTS PR00412 Epoxide hydrolase signature 104 119 1.1E-11 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS05290 e418a0bd024b3c39b49cbfdf05f78026 349 PRINTS PR00412 Epoxide hydrolase signature 324 346 1.1E-11 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS05290 e418a0bd024b3c39b49cbfdf05f78026 349 PRINTS PR00412 Epoxide hydrolase signature 84 102 1.1E-11 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS05290 e418a0bd024b3c39b49cbfdf05f78026 349 PRINTS PR00412 Epoxide hydrolase signature 166 179 1.1E-11 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS05290 e418a0bd024b3c39b49cbfdf05f78026 349 SUPERFAMILY SSF53474 57 345 3.74E-54 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05290 e418a0bd024b3c39b49cbfdf05f78026 349 PANTHER PTHR10992 58 192 5.6E-59 T 23-04-2016 DC74_RS05290 e418a0bd024b3c39b49cbfdf05f78026 349 PANTHER PTHR10992 209 349 5.6E-59 T 23-04-2016 DC74_RS37190 cc6010de947afc661b5939efd368f474 484 Gene3D G3DSA:1.20.1250.20 280 480 5.6E-12 T 23-04-2016 DC74_RS37190 cc6010de947afc661b5939efd368f474 484 Gene3D G3DSA:1.20.1250.20 24 210 6.0E-27 T 23-04-2016 DC74_RS37190 cc6010de947afc661b5939efd368f474 484 SUPERFAMILY SSF103473 16 212 1.83E-54 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS37190 cc6010de947afc661b5939efd368f474 484 SUPERFAMILY SSF103473 265 476 1.83E-54 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS37190 cc6010de947afc661b5939efd368f474 484 PANTHER PTHR23501 7 444 2.7E-127 T 23-04-2016 DC74_RS37190 cc6010de947afc661b5939efd368f474 484 Pfam PF07690 Major Facilitator Superfamily 32 430 2.1E-38 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS37190 cc6010de947afc661b5939efd368f474 484 PANTHER PTHR23501:SF31 7 444 2.7E-127 T 23-04-2016 DC74_RS22670 e4f6ad2f864666bcf6cd85189fafac11 319 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 62 190 4.9E-11 T 23-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 DC74_RS22670 e4f6ad2f864666bcf6cd85189fafac11 319 Gene3D G3DSA:1.10.340.30 49 149 1.9E-34 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS22670 e4f6ad2f864666bcf6cd85189fafac11 319 SUPERFAMILY SSF48150 35 245 3.61E-62 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS22670 e4f6ad2f864666bcf6cd85189fafac11 319 PANTHER PTHR10359 39 264 3.1E-58 T 23-04-2016 DC74_RS22670 e4f6ad2f864666bcf6cd85189fafac11 319 SMART SM00478 66 218 6.2E-35 T 23-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 DC74_RS22670 e4f6ad2f864666bcf6cd85189fafac11 319 ProSitePatterns PS01155 Endonuclease III family signature. 129 158 - T 23-04-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 DC74_RS22670 e4f6ad2f864666bcf6cd85189fafac11 319 Gene3D G3DSA:1.10.1670.10 150 246 4.4E-34 T 23-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal DC74_RS22670 e4f6ad2f864666bcf6cd85189fafac11 319 Pfam PF00633 Helix-hairpin-helix motif 126 155 2.6E-7 T 23-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 DC74_RS22670 e4f6ad2f864666bcf6cd85189fafac11 319 SMART SM00525 219 239 0.0016 T 23-04-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 DC74_RS19505 5ec1670848466b6bfcabb264c30c9e05 216 SUPERFAMILY SSF56784 2 215 1.92E-53 T 23-04-2016 IPR023214 HAD-like domain DC74_RS19505 5ec1670848466b6bfcabb264c30c9e05 216 PANTHER PTHR18901 1 215 2.6E-61 T 23-04-2016 DC74_RS19505 5ec1670848466b6bfcabb264c30c9e05 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 185 7.4E-25 T 23-04-2016 IPR023214 HAD-like domain DC74_RS19505 5ec1670848466b6bfcabb264c30c9e05 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 64 186 1.2E-16 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS19505 5ec1670848466b6bfcabb264c30c9e05 216 Gene3D G3DSA:1.10.150.240 18 83 4.8E-12 T 23-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 DC74_RS19505 5ec1670848466b6bfcabb264c30c9e05 216 Gene3D G3DSA:3.40.50.1000 1 17 1.1E-45 T 23-04-2016 IPR023214 HAD-like domain DC74_RS19505 5ec1670848466b6bfcabb264c30c9e05 216 Gene3D G3DSA:3.40.50.1000 89 215 1.1E-45 T 23-04-2016 IPR023214 HAD-like domain DC74_RS19505 5ec1670848466b6bfcabb264c30c9e05 216 PANTHER PTHR18901:SF9 1 215 2.6E-61 T 23-04-2016 DC74_RS23530 c9f05d66f06ed0627a0b308c0e4fd729 425 PANTHER PTHR10314 36 421 3.8E-198 T 23-04-2016 DC74_RS23530 c9f05d66f06ed0627a0b308c0e4fd729 425 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 91 394 7.7E-63 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS23530 c9f05d66f06ed0627a0b308c0e4fd729 425 TIGRFAM TIGR00260 thrC: threonine synthase 69 399 5.4E-79 T 23-04-2016 IPR004450 Threonine synthase-like DC74_RS23530 c9f05d66f06ed0627a0b308c0e4fd729 425 Gene3D G3DSA:3.40.50.1100 124 208 3.2E-28 T 23-04-2016 DC74_RS23530 c9f05d66f06ed0627a0b308c0e4fd729 425 Gene3D G3DSA:3.40.50.1100 209 404 1.1E-33 T 23-04-2016 DC74_RS23530 c9f05d66f06ed0627a0b308c0e4fd729 425 PANTHER PTHR10314:SF96 36 421 3.8E-198 T 23-04-2016 DC74_RS23530 c9f05d66f06ed0627a0b308c0e4fd729 425 SUPERFAMILY SSF53686 14 404 5.89E-87 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS20080 d953a166fb170c007057b017af8441d5 425 SMART SM00530 11 65 1.1E-12 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS20080 d953a166fb170c007057b017af8441d5 425 SUPERFAMILY SSF47413 7 67 2.39E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS20080 d953a166fb170c007057b017af8441d5 425 SUPERFAMILY SSF48452 86 221 1.68E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20080 d953a166fb170c007057b017af8441d5 425 Gene3D G3DSA:1.25.40.10 88 400 9.0E-15 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20080 d953a166fb170c007057b017af8441d5 425 PANTHER PTHR10245 8 65 7.4E-12 T 23-04-2016 DC74_RS20080 d953a166fb170c007057b017af8441d5 425 Gene3D G3DSA:1.10.260.40 8 87 3.3E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS20080 d953a166fb170c007057b017af8441d5 425 Pfam PF12844 Helix-turn-helix domain 9 65 1.2E-10 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS13520 d41aa5b8075d6911e7fc1565d4cb5748 268 SMART SM00422 1 70 1.7E-20 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS13520 d41aa5b8075d6911e7fc1565d4cb5748 268 Gene3D G3DSA:1.10.1660.10 1 110 2.8E-28 T 23-04-2016 DC74_RS13520 d41aa5b8075d6911e7fc1565d4cb5748 268 SUPERFAMILY SSF46955 1 107 1.03E-23 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS13520 d41aa5b8075d6911e7fc1565d4cb5748 268 Pfam PF13411 MerR HTH family regulatory protein 1 68 7.6E-16 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS13520 d41aa5b8075d6911e7fc1565d4cb5748 268 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.2E-7 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS13520 d41aa5b8075d6911e7fc1565d4cb5748 268 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.2E-7 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS13520 d41aa5b8075d6911e7fc1565d4cb5748 268 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.2E-7 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS13520 d41aa5b8075d6911e7fc1565d4cb5748 268 PANTHER PTHR30204 1 109 1.0E-20 T 23-04-2016 DC74_RS31910 a836f4ac50c9448d90113ec2665a8912 306 SUPERFAMILY SSF51735 119 240 9.11E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31910 a836f4ac50c9448d90113ec2665a8912 306 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 90 8.6E-11 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS31910 a836f4ac50c9448d90113ec2665a8912 306 PANTHER PTHR11695:SF294 15 306 1.4E-82 T 23-04-2016 DC74_RS31910 a836f4ac50c9448d90113ec2665a8912 306 Gene3D G3DSA:3.40.50.720 151 240 2.9E-18 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31910 a836f4ac50c9448d90113ec2665a8912 306 SMART SM00829 10 304 2.9E-27 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS31910 a836f4ac50c9448d90113ec2665a8912 306 Gene3D G3DSA:3.90.180.10 1 150 1.7E-47 T 23-04-2016 IPR011032 GroES-like DC74_RS31910 a836f4ac50c9448d90113ec2665a8912 306 Pfam PF13602 Zinc-binding dehydrogenase 188 304 1.4E-18 T 23-04-2016 DC74_RS31910 a836f4ac50c9448d90113ec2665a8912 306 PANTHER PTHR11695 15 306 1.4E-82 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS31910 a836f4ac50c9448d90113ec2665a8912 306 SUPERFAMILY SSF50129 1 151 2.59E-39 T 23-04-2016 IPR011032 GroES-like DC74_RS26615 32b3cf1b0bb3b8c8634eac4e046b464d 203 Gene3D G3DSA:1.10.3300.10 8 184 1.4E-45 T 23-04-2016 IPR023286 ABATE domain DC74_RS26615 32b3cf1b0bb3b8c8634eac4e046b464d 203 Pfam PF07336 Putative stress-induced transcription regulator 9 122 1.7E-15 T 23-04-2016 IPR010852 Putative stress-induced transcription regulator DC74_RS26615 32b3cf1b0bb3b8c8634eac4e046b464d 203 Pfam PF11706 CGNR zinc finger 141 183 2.2E-15 T 23-04-2016 IPR021005 Zinc finger, CGNR DC74_RS26615 32b3cf1b0bb3b8c8634eac4e046b464d 203 SUPERFAMILY SSF160904 8 182 1.19E-37 T 23-04-2016 DC74_RS26615 32b3cf1b0bb3b8c8634eac4e046b464d 203 PANTHER PTHR35525:SF1 5 190 1.0E-65 T 23-04-2016 DC74_RS26615 32b3cf1b0bb3b8c8634eac4e046b464d 203 PANTHER PTHR35525 5 190 1.0E-65 T 23-04-2016 DC74_RS26070 03873f8103bb55349607d3143ac10659 245 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 30 213 3.2E-94 T 23-04-2016 DC74_RS26070 03873f8103bb55349607d3143ac10659 245 SUPERFAMILY SSF47240 35 156 2.72E-9 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS26070 03873f8103bb55349607d3143ac10659 245 Gene3D G3DSA:1.20.1260.10 33 157 4.0E-8 T 23-04-2016 IPR012347 Ferritin-related DC74_RS18565 c00c9f3c120cee15c05e84779d0b232a 329 PANTHER PTHR10285 290 329 4.7E-150 T 23-04-2016 DC74_RS18565 c00c9f3c120cee15c05e84779d0b232a 329 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 102 263 6.9E-11 T 23-04-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 DC74_RS18565 c00c9f3c120cee15c05e84779d0b232a 329 PANTHER PTHR10285:SF7 290 329 4.7E-150 T 23-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 DC74_RS18565 c00c9f3c120cee15c05e84779d0b232a 329 PANTHER PTHR10285:SF7 7 274 4.7E-150 T 23-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 DC74_RS18565 c00c9f3c120cee15c05e84779d0b232a 329 PANTHER PTHR10285 7 274 4.7E-150 T 23-04-2016 DC74_RS18565 c00c9f3c120cee15c05e84779d0b232a 329 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 17 328 1.1E-123 T 23-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 DC74_RS18565 c00c9f3c120cee15c05e84779d0b232a 329 Hamap MF_00215 Pantothenate kinase [coaA]. 1 329 173.958 T 23-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 DC74_RS18565 c00c9f3c120cee15c05e84779d0b232a 329 SUPERFAMILY SSF52540 14 327 1.54E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18565 c00c9f3c120cee15c05e84779d0b232a 329 Gene3D G3DSA:3.40.50.300 16 327 3.0E-105 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18565 c00c9f3c120cee15c05e84779d0b232a 329 PIRSF PIRSF000545 7 329 5.5E-142 T 23-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 DC74_RS17915 68014599b8aa60377d1e6eff10923da4 356 Pfam PF13672 Protein phosphatase 2C 139 316 6.9E-10 T 23-04-2016 DC74_RS17915 68014599b8aa60377d1e6eff10923da4 356 PANTHER PTHR13832:SF226 18 352 1.0E-82 T 23-04-2016 DC74_RS17915 68014599b8aa60377d1e6eff10923da4 356 SMART SM00332 121 347 7.2E-9 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS17915 68014599b8aa60377d1e6eff10923da4 356 Gene3D G3DSA:1.10.1660.10 2 115 2.2E-21 T 23-04-2016 DC74_RS17915 68014599b8aa60377d1e6eff10923da4 356 Gene3D G3DSA:3.60.40.10 122 349 8.2E-57 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS17915 68014599b8aa60377d1e6eff10923da4 356 SMART SM00331 130 349 2.8E-25 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS17915 68014599b8aa60377d1e6eff10923da4 356 Pfam PF13411 MerR HTH family regulatory protein 3 69 1.1E-13 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17915 68014599b8aa60377d1e6eff10923da4 356 SUPERFAMILY SSF81606 123 348 2.35E-48 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS17915 68014599b8aa60377d1e6eff10923da4 356 PANTHER PTHR13832 18 352 1.0E-82 T 23-04-2016 IPR015655 Protein phosphatase 2C family GO:0004722|GO:0006470 KEGG: 04660+3.1.3.16 DC74_RS17915 68014599b8aa60377d1e6eff10923da4 356 SMART SM00422 2 72 2.1E-16 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17915 68014599b8aa60377d1e6eff10923da4 356 SUPERFAMILY SSF46955 2 102 1.76E-21 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS17915 68014599b8aa60377d1e6eff10923da4 356 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS18380 3d2e9dd783136b60d9bb5029f1dcfa5f 308 PANTHER PTHR34861:SF5 11 308 1.1E-73 T 23-04-2016 DC74_RS18380 3d2e9dd783136b60d9bb5029f1dcfa5f 308 Pfam PF04199 Putative cyclase 88 239 2.6E-23 T 23-04-2016 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|UniPathway: UPA00333 DC74_RS18380 3d2e9dd783136b60d9bb5029f1dcfa5f 308 Gene3D G3DSA:3.50.30.50 85 307 1.7E-31 T 23-04-2016 DC74_RS18380 3d2e9dd783136b60d9bb5029f1dcfa5f 308 SUPERFAMILY SSF102198 91 307 5.62E-23 T 23-04-2016 DC74_RS18380 3d2e9dd783136b60d9bb5029f1dcfa5f 308 PANTHER PTHR34861 11 308 1.1E-73 T 23-04-2016 DC74_RS02900 be55787f2331223f8ef0a306e2a5af5a 415 PANTHER PTHR10277 59 315 8.6E-29 T 23-04-2016 DC74_RS02900 be55787f2331223f8ef0a306e2a5af5a 415 Gene3D G3DSA:3.20.20.70 13 368 1.1E-46 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS02900 be55787f2331223f8ef0a306e2a5af5a 415 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 214 227 - T 23-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS02900 be55787f2331223f8ef0a306e2a5af5a 415 SUPERFAMILY SSF51569 12 316 1.59E-37 T 23-04-2016 DC74_RS02900 be55787f2331223f8ef0a306e2a5af5a 415 Pfam PF00682 HMGL-like 59 298 2.0E-37 T 23-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 DC74_RS36515 01a05eb483e8744c0eb542f16ebbae3b 418 SUPERFAMILY SSF56059 95 337 7.6E-41 T 23-04-2016 DC74_RS36515 01a05eb483e8744c0eb542f16ebbae3b 418 Pfam PF13535 ATP-grasp domain 153 302 3.0E-19 T 23-04-2016 DC74_RS36515 01a05eb483e8744c0eb542f16ebbae3b 418 PANTHER PTHR23132 113 371 4.8E-20 T 23-04-2016 DC74_RS36515 01a05eb483e8744c0eb542f16ebbae3b 418 Gene3D G3DSA:3.30.470.20 115 407 8.1E-35 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 PANTHER PTHR11632 24 564 2.5E-217 T 23-04-2016 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 Gene3D G3DSA:3.50.50.60 21 272 1.0E-95 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 Gene3D G3DSA:3.50.50.60 381 440 1.0E-95 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 Gene3D G3DSA:1.20.58.100 463 569 7.2E-24 T 23-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 28 47 1.7E-11 T 23-04-2016 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 387 409 1.7E-11 T 23-04-2016 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 Pfam PF02910 Fumarate reductase flavoprotein C-term 468 577 1.1E-18 T 23-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 SUPERFAMILY SSF51905 177 296 8.99E-60 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 SUPERFAMILY SSF51905 388 440 8.99E-60 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 SUPERFAMILY SSF51905 12 146 8.99E-60 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 PANTHER PTHR11632:SF27 24 564 2.5E-217 T 23-04-2016 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 Gene3D G3DSA:3.90.700.10 273 380 7.3E-37 T 23-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 Pfam PF00890 FAD binding domain 27 424 5.0E-95 T 23-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 26 553 4.3E-161 T 23-04-2016 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 PIRSF PIRSF000171 22 579 8.6E-35 T 23-04-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 SUPERFAMILY SSF56425 267 384 1.29E-38 T 23-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain DC74_RS22565 815fa4a600e51eb23f2bfa90185652f5 604 SUPERFAMILY SSF46977 466 579 2.09E-28 T 23-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 DC74_RS36730 af626330362ebe0afc3381e3a4746937 257 SUPERFAMILY SSF53335 224 255 2.46E-27 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS36730 af626330362ebe0afc3381e3a4746937 257 SUPERFAMILY SSF53335 7 154 2.46E-27 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS36730 af626330362ebe0afc3381e3a4746937 257 PANTHER PTHR10108 1 161 8.5E-13 T 23-04-2016 DC74_RS36730 af626330362ebe0afc3381e3a4746937 257 PANTHER PTHR10108 185 208 8.5E-13 T 23-04-2016 DC74_RS36730 af626330362ebe0afc3381e3a4746937 257 PANTHER PTHR10108 224 238 8.5E-13 T 23-04-2016 DC74_RS36730 af626330362ebe0afc3381e3a4746937 257 Pfam PF13649 Methyltransferase domain 49 147 1.3E-15 T 23-04-2016 DC74_RS36730 af626330362ebe0afc3381e3a4746937 257 Gene3D G3DSA:3.40.50.150 9 255 1.0E-27 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS36730 af626330362ebe0afc3381e3a4746937 257 PANTHER PTHR10108:SF820 1 161 8.5E-13 T 23-04-2016 DC74_RS36730 af626330362ebe0afc3381e3a4746937 257 PANTHER PTHR10108:SF820 185 208 8.5E-13 T 23-04-2016 DC74_RS36730 af626330362ebe0afc3381e3a4746937 257 PANTHER PTHR10108:SF820 224 238 8.5E-13 T 23-04-2016 DC74_RS21700 5bd3c78bf107af143774ecfd59d30cf1 285 SMART SM00530 12 85 1.1E-7 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS21700 5bd3c78bf107af143774ecfd59d30cf1 285 Pfam PF13560 Helix-turn-helix domain 8 88 5.9E-17 T 23-04-2016 DC74_RS21700 5bd3c78bf107af143774ecfd59d30cf1 285 PANTHER PTHR35010:SF2 4 276 2.3E-99 T 23-04-2016 DC74_RS21700 5bd3c78bf107af143774ecfd59d30cf1 285 PANTHER PTHR35010 4 276 2.3E-99 T 23-04-2016 DC74_RS21700 5bd3c78bf107af143774ecfd59d30cf1 285 SUPERFAMILY SSF47413 33 83 1.51E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS21700 5bd3c78bf107af143774ecfd59d30cf1 285 Gene3D G3DSA:1.10.260.40 4 84 7.8E-17 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 Pfam PF00970 Oxidoreductase FAD-binding domain 11 103 5.0E-11 T 23-04-2016 IPR008333 Oxidoreductase, FAD-binding domain DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 SUPERFAMILY SSF52343 94 227 5.37E-31 T 23-04-2016 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 Gene3D G3DSA:2.40.30.10 5 95 1.4E-26 T 23-04-2016 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 Gene3D G3DSA:3.10.20.30 223 343 5.1E-33 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 Pfam PF00175 Oxidoreductase NAD-binding domain 114 211 5.0E-13 T 23-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 SUPERFAMILY SSF54292 220 345 1.97E-28 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 SUPERFAMILY SSF63380 4 103 1.16E-25 T 23-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 PANTHER PTHR19370 7 234 5.5E-46 T 23-04-2016 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 297 305 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 266 339 6.9E-17 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 PRINTS PR00410 Phenol hydroxylase reductase family signature 197 205 2.6E-12 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 PRINTS PR00410 Phenol hydroxylase reductase family signature 113 132 2.6E-12 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 PRINTS PR00410 Phenol hydroxylase reductase family signature 34 46 2.6E-12 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 137 146 4.7E-7 T 23-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 197 205 4.7E-7 T 23-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 54 61 4.7E-7 T 23-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 113 132 4.7E-7 T 23-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 DC74_RS36415 17b783a7c712b1d74a254b5ff0d65d3f 349 Gene3D G3DSA:3.40.50.80 96 222 1.1E-30 T 23-04-2016 DC74_RS02895 5d9fb99c3ac3daf70c4532ab679b1fd1 72 SUPERFAMILY SSF47473 5 71 1.54E-17 T 23-04-2016 IPR011992 EF-hand domain pair DC74_RS02895 5d9fb99c3ac3daf70c4532ab679b1fd1 72 Pfam PF13499 EF-hand domain pair 8 70 1.2E-13 T 23-04-2016 IPR002048 EF-hand domain GO:0005509 DC74_RS02895 5d9fb99c3ac3daf70c4532ab679b1fd1 72 PANTHER PTHR10891 10 71 5.9E-12 T 23-04-2016 DC74_RS02895 5d9fb99c3ac3daf70c4532ab679b1fd1 72 SMART SM00054 45 70 12.0 T 23-04-2016 IPR002048 EF-hand domain GO:0005509 DC74_RS02895 5d9fb99c3ac3daf70c4532ab679b1fd1 72 SMART SM00054 8 36 5.1E-4 T 23-04-2016 IPR002048 EF-hand domain GO:0005509 DC74_RS02895 5d9fb99c3ac3daf70c4532ab679b1fd1 72 Gene3D G3DSA:1.10.238.10 6 70 3.8E-18 T 23-04-2016 IPR011992 EF-hand domain pair DC74_RS02895 5d9fb99c3ac3daf70c4532ab679b1fd1 72 ProSitePatterns PS00018 EF-hand calcium-binding domain. 54 66 - T 23-04-2016 IPR018247 EF-Hand 1, calcium-binding site DC74_RS02895 5d9fb99c3ac3daf70c4532ab679b1fd1 72 ProSitePatterns PS00018 EF-hand calcium-binding domain. 17 29 - T 23-04-2016 IPR018247 EF-Hand 1, calcium-binding site DC74_RS36535 20482d8948d80d2798eb9ac6b9cc2cf3 395 Gene3D G3DSA:3.30.470.20 107 311 1.3E-13 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS36535 20482d8948d80d2798eb9ac6b9cc2cf3 395 SUPERFAMILY SSF56059 102 312 1.79E-25 T 23-04-2016 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 SMART SM01008 220 299 9.1E-6 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 622 677 2.2E-7 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 329 557 2.8E-19 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 56 197 1.1E-16 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 Gene3D G3DSA:3.90.1170.50 201 273 1.1E-13 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 Gene3D G3DSA:3.30.365.10 62 200 1.4E-29 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 PANTHER PTHR11908:SF2 79 467 2.4E-68 T 23-04-2016 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 PANTHER PTHR11908:SF2 485 748 2.4E-68 T 23-04-2016 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 PANTHER PTHR11908 485 748 2.4E-68 T 23-04-2016 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 Gene3D G3DSA:3.30.365.10 344 431 1.1E-20 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 SUPERFAMILY SSF56003 58 252 1.5E-29 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 SUPERFAMILY SSF56003 326 732 2.21E-79 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 PANTHER PTHR11908 79 467 2.4E-68 T 23-04-2016 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 Gene3D G3DSA:3.30.365.10 528 733 2.4E-28 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS05885 e5b778deb6bf1fc5bb4a42146c96bbc3 761 PIRSF PIRSF036389 1 737 2.4E-157 T 23-04-2016 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related DC74_RS08200 32a4bff4951f5d4044cb13d6267cd7f9 366 SMART SM00382 52 235 7.3E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS08200 32a4bff4951f5d4044cb13d6267cd7f9 366 PANTHER PTHR24220 24 266 7.1E-120 T 23-04-2016 DC74_RS08200 32a4bff4951f5d4044cb13d6267cd7f9 366 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS08200 32a4bff4951f5d4044cb13d6267cd7f9 366 PANTHER PTHR24220:SF150 24 266 7.1E-120 T 23-04-2016 DC74_RS08200 32a4bff4951f5d4044cb13d6267cd7f9 366 SUPERFAMILY SSF50331 269 363 1.42E-7 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal DC74_RS08200 32a4bff4951f5d4044cb13d6267cd7f9 366 SUPERFAMILY SSF52540 24 264 9.87E-82 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS08200 32a4bff4951f5d4044cb13d6267cd7f9 366 Pfam PF00005 ABC transporter 43 185 5.7E-36 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS08200 32a4bff4951f5d4044cb13d6267cd7f9 366 Pfam PF08402 TOBE domain 280 362 1.4E-10 T 23-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 DC74_RS08200 32a4bff4951f5d4044cb13d6267cd7f9 366 Gene3D G3DSA:3.40.50.300 14 259 9.6E-80 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10615 bbe7c86df9b9fdb4d59409b5a76ce0fa 550 Pfam PF00501 AMP-binding enzyme 31 455 8.9E-99 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS10615 bbe7c86df9b9fdb4d59409b5a76ce0fa 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 465 540 1.4E-24 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS10615 bbe7c86df9b9fdb4d59409b5a76ce0fa 550 PANTHER PTHR24096 18 155 1.3E-158 T 23-04-2016 DC74_RS10615 bbe7c86df9b9fdb4d59409b5a76ce0fa 550 PANTHER PTHR24096 177 550 1.3E-158 T 23-04-2016 DC74_RS10615 bbe7c86df9b9fdb4d59409b5a76ce0fa 550 Gene3D G3DSA:2.30.38.10 375 447 5.1E-26 T 23-04-2016 DC74_RS10615 bbe7c86df9b9fdb4d59409b5a76ce0fa 550 Gene3D G3DSA:3.40.50.980 210 368 1.7E-38 T 23-04-2016 DC74_RS10615 bbe7c86df9b9fdb4d59409b5a76ce0fa 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 205 216 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS10615 bbe7c86df9b9fdb4d59409b5a76ce0fa 550 SUPERFAMILY SSF56801 19 549 5.23E-156 T 23-04-2016 DC74_RS10615 bbe7c86df9b9fdb4d59409b5a76ce0fa 550 Gene3D G3DSA:3.40.50.980 29 209 1.1E-38 T 23-04-2016 DC74_RS10615 bbe7c86df9b9fdb4d59409b5a76ce0fa 550 Gene3D G3DSA:3.30.300.30 451 549 1.4E-35 T 23-04-2016 DC74_RS09550 c8e58b25e8f21cbc07e496d1b19b7896 250 SUPERFAMILY SSF50475 72 248 5.1E-17 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS09550 c8e58b25e8f21cbc07e496d1b19b7896 250 Pfam PF10615 Protein of unknown function (DUF2470) 162 241 5.2E-6 T 23-04-2016 IPR019595 Domain of unknown function DUF2470 DC74_RS09550 c8e58b25e8f21cbc07e496d1b19b7896 250 PANTHER PTHR13343 74 249 2.1E-12 T 23-04-2016 DC74_RS09550 c8e58b25e8f21cbc07e496d1b19b7896 250 Gene3D G3DSA:3.20.180.10 157 248 1.4E-7 T 23-04-2016 IPR019595 Domain of unknown function DUF2470 DC74_RS12325 1cac5a3d7dc3090980768269d8b249d5 511 PANTHER PTHR11236 11 506 1.5E-240 T 23-04-2016 DC74_RS12325 1cac5a3d7dc3090980768269d8b249d5 511 Gene3D G3DSA:3.60.120.10 22 506 3.4E-175 T 23-04-2016 IPR005801 ADC synthase GO:0009058 DC74_RS12325 1cac5a3d7dc3090980768269d8b249d5 511 PANTHER PTHR11236:SF9 11 506 1.5E-240 T 23-04-2016 DC74_RS12325 1cac5a3d7dc3090980768269d8b249d5 511 Pfam PF00425 chorismate binding enzyme 238 495 2.9E-96 T 23-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal DC74_RS12325 1cac5a3d7dc3090980768269d8b249d5 511 PRINTS PR00095 Anthranilate synthase component I signature 437 451 1.2E-23 T 23-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 DC74_RS12325 1cac5a3d7dc3090980768269d8b249d5 511 PRINTS PR00095 Anthranilate synthase component I signature 343 356 1.2E-23 T 23-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 DC74_RS12325 1cac5a3d7dc3090980768269d8b249d5 511 PRINTS PR00095 Anthranilate synthase component I signature 452 466 1.2E-23 T 23-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 DC74_RS12325 1cac5a3d7dc3090980768269d8b249d5 511 PRINTS PR00095 Anthranilate synthase component I signature 357 370 1.2E-23 T 23-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 DC74_RS12325 1cac5a3d7dc3090980768269d8b249d5 511 SUPERFAMILY SSF56322 24 504 5.36E-156 T 23-04-2016 IPR005801 ADC synthase GO:0009058 DC74_RS12325 1cac5a3d7dc3090980768269d8b249d5 511 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 35 504 2.1E-173 T 23-04-2016 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 DC74_RS12325 1cac5a3d7dc3090980768269d8b249d5 511 Pfam PF04715 Anthranilate synthase component I, N terminal region 36 179 1.7E-31 T 23-04-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 DC74_RS01065 90422f29a5c921870292e6bdd9a2ac22 145 Pfam PF00462 Glutaredoxin 70 127 2.3E-6 T 23-04-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 DC74_RS01065 90422f29a5c921870292e6bdd9a2ac22 145 Gene3D G3DSA:3.40.30.10 71 140 1.6E-8 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS01065 90422f29a5c921870292e6bdd9a2ac22 145 SUPERFAMILY SSF52833 71 141 1.03E-10 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS01065 90422f29a5c921870292e6bdd9a2ac22 145 PANTHER PTHR34386:SF1 30 143 5.7E-36 T 23-04-2016 DC74_RS01065 90422f29a5c921870292e6bdd9a2ac22 145 PANTHER PTHR34386 30 143 5.7E-36 T 23-04-2016 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 PANTHER PTHR12128:SF34 2 282 1.3E-70 T 23-04-2016 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 SMART SM01130 6 295 1.2E-78 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 1.6E-19 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 135 152 1.6E-19 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 1.6E-19 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 110 126 1.6E-19 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 6 293 41.461 T 23-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 PIRSF PIRSF001365 2 298 3.0E-68 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 12 286 4.5E-62 T 23-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 140 170 - T 23-04-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 Pfam PF00701 Dihydrodipicolinate synthetase family 7 287 7.3E-57 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 SUPERFAMILY SSF51569 4 297 3.56E-71 T 23-04-2016 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 Gene3D G3DSA:3.20.20.70 1 296 8.1E-80 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS07805 1d0bc8ea38a6f9829e79c71c3a39069b 298 PANTHER PTHR12128 2 282 1.3E-70 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS39370 bf9836e8e097835b811e98976c16b395 135 PANTHER PTHR35174:SF3 3 131 9.1E-29 T 23-04-2016 DC74_RS39370 bf9836e8e097835b811e98976c16b395 135 PANTHER PTHR35174 3 131 9.1E-29 T 23-04-2016 DC74_RS39370 bf9836e8e097835b811e98976c16b395 135 SUPERFAMILY SSF54909 21 125 7.33E-23 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS39370 bf9836e8e097835b811e98976c16b395 135 Pfam PF03795 YCII-related domain 17 107 1.3E-10 T 23-04-2016 IPR005545 YCII-related DC74_RS39370 bf9836e8e097835b811e98976c16b395 135 Gene3D G3DSA:3.30.70.1060 1 130 2.5E-38 T 23-04-2016 DC74_RS00190 1f1618c8b2476f5080b4455a73142e8c 437 TIGRFAM TIGR02678 TIGR02678: TIGR02678 family protein 19 413 4.5E-137 T 23-04-2016 IPR013494 Conserved hypothetical protein CHP02678 DC74_RS00190 1f1618c8b2476f5080b4455a73142e8c 437 Pfam PF09661 Protein of unknown function (DUF2398) 20 409 1.1E-111 T 23-04-2016 IPR013494 Conserved hypothetical protein CHP02678 DC74_RS12750 e268c13a36bb10a2d5a6ab1717c9e992 265 Pfam PF12146 Serine aminopeptidase, S33 19 229 1.2E-20 T 23-04-2016 IPR022742 Serine aminopeptidase, S33 DC74_RS12750 e268c13a36bb10a2d5a6ab1717c9e992 265 SUPERFAMILY SSF53474 15 246 2.04E-36 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS12750 e268c13a36bb10a2d5a6ab1717c9e992 265 PIRSF PIRSF017388 1 248 2.7E-75 T 23-04-2016 IPR012354 Esterase/lipase GO:0052689 DC74_RS12750 e268c13a36bb10a2d5a6ab1717c9e992 265 Gene3D G3DSA:3.40.50.1820 14 245 2.6E-51 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS12750 e268c13a36bb10a2d5a6ab1717c9e992 265 PANTHER PTHR11614 19 257 1.8E-32 T 23-04-2016 DC74_RS13580 3accc657b50c39620b63dbe314641a31 418 PANTHER PTHR24421:SF22 63 418 1.6E-101 T 23-04-2016 DC74_RS13580 3accc657b50c39620b63dbe314641a31 418 Gene3D G3DSA:3.30.565.10 303 405 8.4E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS13580 3accc657b50c39620b63dbe314641a31 418 Pfam PF07730 Histidine kinase 207 273 1.6E-14 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS13580 3accc657b50c39620b63dbe314641a31 418 SUPERFAMILY SSF55874 288 404 1.96E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS13580 3accc657b50c39620b63dbe314641a31 418 PANTHER PTHR24421 63 418 1.6E-101 T 23-04-2016 DC74_RS20420 6a98cb03c50482f8559f1c5c8d22a247 344 SMART SM00861 13 188 6.1E-67 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain DC74_RS20420 6a98cb03c50482f8559f1c5c8d22a247 344 Gene3D G3DSA:3.40.50.970 11 206 1.7E-75 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS20420 6a98cb03c50482f8559f1c5c8d22a247 344 Pfam PF02779 Transketolase, pyrimidine binding domain 13 186 1.2E-45 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain DC74_RS20420 6a98cb03c50482f8559f1c5c8d22a247 344 PANTHER PTHR11624:SF79 11 344 3.4E-192 T 23-04-2016 DC74_RS20420 6a98cb03c50482f8559f1c5c8d22a247 344 PANTHER PTHR11624 11 344 3.4E-192 T 23-04-2016 IPR033247 Transketolase family DC74_RS20420 6a98cb03c50482f8559f1c5c8d22a247 344 Pfam PF02780 Transketolase, C-terminal domain 204 325 7.7E-38 T 23-04-2016 IPR033248 Transketolase, C-terminal domain DC74_RS20420 6a98cb03c50482f8559f1c5c8d22a247 344 SUPERFAMILY SSF52922 200 331 8.25E-39 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS20420 6a98cb03c50482f8559f1c5c8d22a247 344 Gene3D G3DSA:3.40.50.920 207 329 2.5E-41 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS20420 6a98cb03c50482f8559f1c5c8d22a247 344 SUPERFAMILY SSF52518 12 196 2.31E-67 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS25540 0ebb7f8a8c7532110a8661276f4095ee 228 SUPERFAMILY SSF52540 7 223 5.19E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25540 0ebb7f8a8c7532110a8661276f4095ee 228 PANTHER PTHR24220:SF559 9 224 6.5E-110 T 23-04-2016 DC74_RS25540 0ebb7f8a8c7532110a8661276f4095ee 228 PANTHER PTHR24220 9 224 6.5E-110 T 23-04-2016 DC74_RS25540 0ebb7f8a8c7532110a8661276f4095ee 228 Gene3D G3DSA:3.40.50.300 6 220 1.3E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25540 0ebb7f8a8c7532110a8661276f4095ee 228 Pfam PF00005 ABC transporter 23 171 1.0E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS25540 0ebb7f8a8c7532110a8661276f4095ee 228 SMART SM00382 32 221 3.2E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS21180 8b8872edefac596ddf5cfb12f164c203 437 PANTHER PTHR30521 68 437 7.1E-133 T 23-04-2016 DC74_RS21180 8b8872edefac596ddf5cfb12f164c203 437 SUPERFAMILY SSF54909 86 429 7.51E-81 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS21180 8b8872edefac596ddf5cfb12f164c203 437 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 28 436 2.6E-143 T 23-04-2016 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 KEGG: 00480+1.11.1.- DC74_RS21180 8b8872edefac596ddf5cfb12f164c203 437 PANTHER PTHR30521:SF4 68 437 7.1E-133 T 23-04-2016 DC74_RS21180 8b8872edefac596ddf5cfb12f164c203 437 Pfam PF04261 Dyp-type peroxidase family 88 424 5.7E-102 T 23-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- DC74_RS21180 8b8872edefac596ddf5cfb12f164c203 437 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 88 423 1.2E-91 T 23-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 SUPERFAMILY SSF52540 5 229 7.01E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 Pfam PF00005 ABC transporter 22 187 4.6E-22 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 Pfam PF00005 ABC transporter 367 498 3.3E-14 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 PANTHER PTHR19211 14 293 2.1E-263 T 23-04-2016 DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 PANTHER PTHR19211 314 548 2.1E-263 T 23-04-2016 DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 Gene3D G3DSA:3.40.50.300 136 277 4.8E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 Gene3D G3DSA:3.40.50.300 7 100 4.8E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 Gene3D G3DSA:3.40.50.300 365 546 8.1E-30 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 SUPERFAMILY SSF52540 364 545 2.17E-35 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 SMART SM00382 29 232 8.7E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 SMART SM00382 374 544 2.5E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 PANTHER PTHR19211:SF46 14 293 2.1E-263 T 23-04-2016 DC74_RS33150 4c2c0b7e4930a508083d0e1e65b425c5 550 PANTHER PTHR19211:SF46 314 548 2.1E-263 T 23-04-2016 DC74_RS11425 3bc33f6d65d4f62d90225c22b076558c 594 SUPERFAMILY SSF48208 195 590 1.45E-105 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 DC74_RS11425 3bc33f6d65d4f62d90225c22b076558c 594 PANTHER PTHR31616:SF0 3 590 5.3E-190 T 23-04-2016 DC74_RS11425 3bc33f6d65d4f62d90225c22b076558c 594 PANTHER PTHR31616 3 590 5.3E-190 T 23-04-2016 DC74_RS11425 3bc33f6d65d4f62d90225c22b076558c 594 Gene3D G3DSA:1.50.10.10 213 591 7.6E-84 T 23-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 DC74_RS11425 3bc33f6d65d4f62d90225c22b076558c 594 Pfam PF00723 Glycosyl hydrolases family 15 217 581 9.6E-66 T 23-04-2016 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: REACT_474 DC74_RS15160 819d24311495e303210e3c0e2f92d44b 628 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 541 626 3.6E-10 T 23-04-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain DC74_RS15160 819d24311495e303210e3c0e2f92d44b 628 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 326 454 5.1E-6 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS02760 21d041955a6092c3124006a58efeacac 372 SUPERFAMILY SSF48179 166 251 1.25E-20 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS02760 21d041955a6092c3124006a58efeacac 372 PANTHER PTHR21363:SF0 3 289 2.2E-55 T 23-04-2016 DC74_RS02760 21d041955a6092c3124006a58efeacac 372 Gene3D G3DSA:3.40.50.720 3 171 6.8E-23 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02760 21d041955a6092c3124006a58efeacac 372 Pfam PF02153 Prephenate dehydrogenase 16 251 2.1E-54 T 23-04-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 DC74_RS02760 21d041955a6092c3124006a58efeacac 372 SUPERFAMILY SSF51735 4 159 1.48E-27 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02760 21d041955a6092c3124006a58efeacac 372 PANTHER PTHR21363 3 289 2.2E-55 T 23-04-2016 DC74_RS04625 2497feb9e6fec105fe5db52c580cd90a 402 PANTHER PTHR23513 16 402 5.8E-44 T 23-04-2016 DC74_RS04625 2497feb9e6fec105fe5db52c580cd90a 402 Gene3D G3DSA:1.20.1250.20 6 191 1.7E-14 T 23-04-2016 DC74_RS04625 2497feb9e6fec105fe5db52c580cd90a 402 Gene3D G3DSA:1.20.1250.20 219 397 4.7E-18 T 23-04-2016 DC74_RS04625 2497feb9e6fec105fe5db52c580cd90a 402 Pfam PF07690 Major Facilitator Superfamily 14 234 5.5E-19 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS04625 2497feb9e6fec105fe5db52c580cd90a 402 SUPERFAMILY SSF103473 3 398 6.67E-42 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05260 f6ebaa26258db562d8ec61478a78362c 369 PANTHER PTHR10314 2 359 9.7E-71 T 23-04-2016 DC74_RS05260 f6ebaa26258db562d8ec61478a78362c 369 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 301 3.2E-46 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS05260 f6ebaa26258db562d8ec61478a78362c 369 PANTHER PTHR10314:SF8 2 359 9.7E-71 T 23-04-2016 DC74_RS05260 f6ebaa26258db562d8ec61478a78362c 369 SUPERFAMILY SSF53686 4 320 3.8E-61 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS05260 f6ebaa26258db562d8ec61478a78362c 369 Gene3D G3DSA:3.40.50.1100 149 315 7.5E-37 T 23-04-2016 DC74_RS05260 f6ebaa26258db562d8ec61478a78362c 369 Gene3D G3DSA:3.40.50.1100 49 148 1.1E-18 T 23-04-2016 DC74_RS20110 701494685edcfbb42e074f3908442b87 157 PANTHER PTHR34134 7 141 1.6E-32 T 23-04-2016 DC74_RS20110 701494685edcfbb42e074f3908442b87 157 Pfam PF03965 Penicillinase repressor 23 130 2.7E-23 T 23-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 DC74_RS20110 701494685edcfbb42e074f3908442b87 157 SUPERFAMILY SSF46785 24 133 8.44E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20110 701494685edcfbb42e074f3908442b87 157 Gene3D G3DSA:1.10.10.10 24 90 1.1E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06315 60f749cfa61b1eab1e4e455a29e7c43b 67 PRINTS PR00050 Cold shock protein signature 4 19 8.1E-18 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS06315 60f749cfa61b1eab1e4e455a29e7c43b 67 PRINTS PR00050 Cold shock protein signature 40 58 8.1E-18 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS06315 60f749cfa61b1eab1e4e455a29e7c43b 67 PRINTS PR00050 Cold shock protein signature 25 34 8.1E-18 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS06315 60f749cfa61b1eab1e4e455a29e7c43b 67 PANTHER PTHR11544 1 67 1.6E-40 T 23-04-2016 DC74_RS06315 60f749cfa61b1eab1e4e455a29e7c43b 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 23-04-2016 IPR019844 Cold-shock conserved site DC74_RS06315 60f749cfa61b1eab1e4e455a29e7c43b 67 SMART SM00357 3 67 9.9E-33 T 23-04-2016 IPR011129 Cold shock protein GO:0003676 DC74_RS06315 60f749cfa61b1eab1e4e455a29e7c43b 67 SUPERFAMILY SSF50249 1 66 7.71E-26 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS06315 60f749cfa61b1eab1e4e455a29e7c43b 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 7.8E-32 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS06315 60f749cfa61b1eab1e4e455a29e7c43b 67 Gene3D G3DSA:2.40.50.140 1 65 7.0E-32 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS06315 60f749cfa61b1eab1e4e455a29e7c43b 67 PIRSF PIRSF002599 1 67 3.1E-26 T 23-04-2016 IPR012156 Cold shock, CspA GO:0003676 DC74_RS33585 09cc3539a6cfcab6ca06b3b3aa6f0a5b 695 Pfam PF02342 TerD domain 546 690 1.0E-19 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS33585 09cc3539a6cfcab6ca06b3b3aa6f0a5b 695 PANTHER PTHR30015:SF4 395 512 4.6E-29 T 23-04-2016 DC74_RS33585 09cc3539a6cfcab6ca06b3b3aa6f0a5b 695 PANTHER PTHR30015 395 512 4.6E-29 T 23-04-2016 DC74_RS33585 09cc3539a6cfcab6ca06b3b3aa6f0a5b 695 Gene3D G3DSA:2.60.60.30 547 687 5.9E-19 T 23-04-2016 DC74_RS33585 09cc3539a6cfcab6ca06b3b3aa6f0a5b 695 Pfam PF04471 Restriction endonuclease 397 509 8.5E-31 T 23-04-2016 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 DC74_RS33585 09cc3539a6cfcab6ca06b3b3aa6f0a5b 695 Gene3D G3DSA:3.40.1350.10 393 508 2.3E-21 T 23-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 DC74_RS33585 09cc3539a6cfcab6ca06b3b3aa6f0a5b 695 SUPERFAMILY SSF52980 401 509 1.18E-19 T 23-04-2016 IPR011335 Restriction endonuclease type II-like DC74_RS28450 e10da77788e179a23c755c2ed5b42879 308 SUPERFAMILY SSF55120 9 229 1.92E-67 T 23-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS28450 e10da77788e179a23c755c2ed5b42879 308 PANTHER PTHR13767:SF2 9 307 3.5E-105 T 23-04-2016 DC74_RS28450 e10da77788e179a23c755c2ed5b42879 308 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 226 3.0E-63 T 23-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS28450 e10da77788e179a23c755c2ed5b42879 308 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 31 187 1.3E-45 T 23-04-2016 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 DC74_RS28450 e10da77788e179a23c755c2ed5b42879 308 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 251 308 1.3E-17 T 23-04-2016 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS28450 e10da77788e179a23c755c2ed5b42879 308 PANTHER PTHR13767 9 307 3.5E-105 T 23-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS28450 e10da77788e179a23c755c2ed5b42879 308 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 188 231 8.2E-14 T 23-04-2016 IPR032819 tRNA pseudouridylate synthase B, C-terminal DC74_RS28450 e10da77788e179a23c755c2ed5b42879 308 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 8 307 16.498 T 23-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS28450 e10da77788e179a23c755c2ed5b42879 308 SUPERFAMILY SSF88697 251 307 2.68E-9 T 23-04-2016 IPR015947 PUA-like domain DC74_RS07315 4d0317ceb1a6c454f9b63ea94c953e89 268 PANTHER PTHR30632:SF0 41 266 8.5E-48 T 23-04-2016 DC74_RS07315 4d0317ceb1a6c454f9b63ea94c953e89 268 Pfam PF13531 Bacterial extracellular solute-binding protein 51 266 1.4E-46 T 23-04-2016 DC74_RS07315 4d0317ceb1a6c454f9b63ea94c953e89 268 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 56 262 8.0E-41 T 23-04-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 DC74_RS07315 4d0317ceb1a6c454f9b63ea94c953e89 268 Gene3D G3DSA:3.40.190.10 48 174 1.5E-34 T 23-04-2016 DC74_RS07315 4d0317ceb1a6c454f9b63ea94c953e89 268 SUPERFAMILY SSF53850 50 267 9.37E-55 T 23-04-2016 DC74_RS07315 4d0317ceb1a6c454f9b63ea94c953e89 268 Gene3D G3DSA:3.40.190.10 183 257 4.2E-7 T 23-04-2016 DC74_RS07315 4d0317ceb1a6c454f9b63ea94c953e89 268 PANTHER PTHR30632 41 266 8.5E-48 T 23-04-2016 DC74_RS07315 4d0317ceb1a6c454f9b63ea94c953e89 268 PIRSF PIRSF004846 6 268 2.8E-65 T 23-04-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 DC74_RS37805 a4225278b4cc2f88980117399a735902 160 PANTHER PTHR11527:SF42 6 159 2.2E-28 T 23-04-2016 DC74_RS37805 a4225278b4cc2f88980117399a735902 160 Gene3D G3DSA:2.60.40.790 27 158 1.3E-33 T 23-04-2016 IPR008978 HSP20-like chaperone DC74_RS37805 a4225278b4cc2f88980117399a735902 160 SUPERFAMILY SSF49764 40 158 5.02E-31 T 23-04-2016 IPR008978 HSP20-like chaperone DC74_RS37805 a4225278b4cc2f88980117399a735902 160 Pfam PF00011 Hsp20/alpha crystallin family 62 158 1.9E-21 T 23-04-2016 IPR002068 Alpha crystallin/Hsp20 domain DC74_RS37805 a4225278b4cc2f88980117399a735902 160 PANTHER PTHR11527 6 159 2.2E-28 T 23-04-2016 IPR031107 Small heat shock protein HSP20 DC74_RS14870 d9e0bd65bf06fec9cdd1725e0a7f7977 230 PANTHER PTHR30055 4 213 2.6E-19 T 23-04-2016 DC74_RS14870 d9e0bd65bf06fec9cdd1725e0a7f7977 230 Pfam PF13977 Bacterial transcriptional repressor 103 184 6.1E-10 T 23-04-2016 DC74_RS14870 d9e0bd65bf06fec9cdd1725e0a7f7977 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 4.3E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS14870 d9e0bd65bf06fec9cdd1725e0a7f7977 230 SUPERFAMILY SSF46689 10 79 1.28E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS14870 d9e0bd65bf06fec9cdd1725e0a7f7977 230 SUPERFAMILY SSF48498 90 187 3.71E-13 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS14870 d9e0bd65bf06fec9cdd1725e0a7f7977 230 Gene3D G3DSA:1.10.357.10 11 190 2.9E-32 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS09700 128eacff6e6b9f138fc64e7f67385c24 241 PANTHER PTHR30231:SF9 6 237 2.1E-76 T 23-04-2016 DC74_RS09700 128eacff6e6b9f138fc64e7f67385c24 241 PANTHER PTHR30231 6 237 2.1E-76 T 23-04-2016 DC74_RS09700 128eacff6e6b9f138fc64e7f67385c24 241 Pfam PF00929 Exonuclease 11 179 4.8E-13 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III DC74_RS09700 128eacff6e6b9f138fc64e7f67385c24 241 SMART SM00479 8 189 1.3E-19 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III DC74_RS09700 128eacff6e6b9f138fc64e7f67385c24 241 SUPERFAMILY SSF53098 4 199 9.11E-40 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS09700 128eacff6e6b9f138fc64e7f67385c24 241 Gene3D G3DSA:3.30.420.10 3 187 4.9E-38 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS29850 ea2c6f8a12076dfd6f372af418da03e7 302 SUPERFAMILY SSF52540 10 210 5.23E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29850 ea2c6f8a12076dfd6f372af418da03e7 302 SMART SM00382 35 206 9.1E-6 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS29850 ea2c6f8a12076dfd6f372af418da03e7 302 Pfam PF00005 ABC transporter 26 156 6.4E-18 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS29850 ea2c6f8a12076dfd6f372af418da03e7 302 Gene3D G3DSA:3.40.50.300 3 210 2.9E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29850 ea2c6f8a12076dfd6f372af418da03e7 302 PANTHER PTHR24220 10 214 1.6E-42 T 23-04-2016 DC74_RS24640 786bf5b707e9c3d25cb6b644a21ab84c 730 SUPERFAMILY SSF51161 354 469 1.52E-15 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS24640 786bf5b707e9c3d25cb6b644a21ab84c 730 SUPERFAMILY SSF51161 121 235 9.56E-19 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS24640 786bf5b707e9c3d25cb6b644a21ab84c 730 Gene3D G3DSA:2.160.10.10 608 707 1.6E-17 T 23-04-2016 DC74_RS24640 786bf5b707e9c3d25cb6b644a21ab84c 730 SUPERFAMILY SSF51161 595 708 6.52E-16 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS24640 786bf5b707e9c3d25cb6b644a21ab84c 730 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 22 706 1.0E-164 T 23-04-2016 IPR012728 Non-ribosomal peptide synthetase, C-terminal DC74_RS24640 786bf5b707e9c3d25cb6b644a21ab84c 730 Gene3D G3DSA:2.160.10.10 127 238 3.3E-18 T 23-04-2016 DC74_RS24640 786bf5b707e9c3d25cb6b644a21ab84c 730 Gene3D G3DSA:2.160.10.10 367 472 6.4E-15 T 23-04-2016 DC74_RS22405 ee87c43efc104a1be8132c66882fe214 229 PANTHER PTHR30353 9 221 2.5E-95 T 23-04-2016 IPR032818 DedA family DC74_RS22405 ee87c43efc104a1be8132c66882fe214 229 PANTHER PTHR30353:SF0 9 221 2.5E-95 T 23-04-2016 DC74_RS22405 ee87c43efc104a1be8132c66882fe214 229 Pfam PF09335 SNARE associated Golgi protein 41 168 2.4E-24 T 23-04-2016 IPR032816 SNARE associated Golgi protein DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 SUPERFAMILY SSF158472 217 267 1.57E-7 T 23-04-2016 DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 Pfam PF00512 His Kinase A (phospho-acceptor) domain 272 333 2.9E-12 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 Gene3D G3DSA:3.30.565.10 344 482 3.7E-27 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 SUPERFAMILY SSF55874 343 480 1.83E-27 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 SMART SM00304 217 270 7.0E-13 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 380 480 2.8E-15 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 SMART SM00388 271 338 1.2E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 SMART SM00387 378 485 4.4E-21 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 440 1.3E-9 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 426 1.3E-9 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 1.3E-9 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 Pfam PF00672 HAMP domain 199 266 1.8E-16 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 PANTHER PTHR24423 8 31 1.4E-51 T 23-04-2016 DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 PANTHER PTHR24423 211 481 1.4E-51 T 23-04-2016 DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 Gene3D G3DSA:1.10.287.130 261 333 1.6E-12 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS27420 218ddf338b597fb05fc1dffb9724d8cb 501 SUPERFAMILY SSF47384 254 333 1.02E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS04790 3d03251208c192582e6a5ca8db899535 246 PANTHER PTHR11926:SF77 38 234 1.4E-49 T 23-04-2016 DC74_RS04790 3d03251208c192582e6a5ca8db899535 246 SUPERFAMILY SSF53756 9 240 1.92E-55 T 23-04-2016 DC74_RS04790 3d03251208c192582e6a5ca8db899535 246 Gene3D G3DSA:3.40.50.2000 9 80 8.6E-23 T 23-04-2016 DC74_RS04790 3d03251208c192582e6a5ca8db899535 246 Gene3D G3DSA:3.40.50.2000 81 227 2.7E-56 T 23-04-2016 DC74_RS04790 3d03251208c192582e6a5ca8db899535 246 PANTHER PTHR11926 38 234 1.4E-49 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS04790 3d03251208c192582e6a5ca8db899535 246 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 142 216 5.8E-7 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS14300 f9c972d86d2e360fe4d21eb5e8f98d03 266 Pfam PF03837 RecT family 6 184 6.7E-20 T 23-04-2016 IPR018330 RecT family GO:0003677|GO:0006259 DC74_RS14300 f9c972d86d2e360fe4d21eb5e8f98d03 266 TIGRFAM TIGR01913 bet_lambda: phage recombination protein Bet 11 180 1.1E-22 T 23-04-2016 IPR010183 Bacteriophage lambda, Bet DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 PANTHER PTHR23135 4 455 1.9E-179 T 23-04-2016 DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 SUPERFAMILY SSF51984 10 98 3.01E-27 T 23-04-2016 DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 Gene3D G3DSA:3.40.1190.10 99 319 2.6E-73 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 SUPERFAMILY SSF53244 317 463 2.38E-40 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 9 467 38.451 T 23-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 Gene3D G3DSA:3.40.50.720 11 98 1.8E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 Pfam PF08245 Mur ligase middle domain 115 297 4.0E-24 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 Pfam PF01225 Mur ligase family, catalytic domain 13 109 1.6E-27 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 SUPERFAMILY SSF53623 96 315 3.4E-57 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 406 2.5E-19 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 Gene3D G3DSA:3.90.190.20 320 465 1.0E-46 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 13 459 6.1E-139 T 23-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS29900 86ff4d313445efb7bc6c6ab1c57be390 467 PANTHER PTHR23135:SF5 4 455 1.9E-179 T 23-04-2016 DC74_RS14350 d576302a8e29f1c4c694db2e31555bae 1416 Pfam PF10145 Phage-related minor tail protein 163 359 4.1E-36 T 23-04-2016 IPR010090 Phage tail tape measure protein DC74_RS14350 d576302a8e29f1c4c694db2e31555bae 1416 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 119 435 2.3E-45 T 23-04-2016 IPR010090 Phage tail tape measure protein DC74_RS29710 e47cf7e2f7f798f2e3e728ac836346a7 1146 Gene3D G3DSA:2.70.98.10 267 561 1.6E-71 T 23-04-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 DC74_RS29710 e47cf7e2f7f798f2e3e728ac836346a7 1146 Gene3D G3DSA:3.30.2080.10 861 1008 4.3E-61 T 23-04-2016 DC74_RS29710 e47cf7e2f7f798f2e3e728ac836346a7 1146 Gene3D G3DSA:1.20.1610.10 691 860 4.8E-51 T 23-04-2016 DC74_RS29710 e47cf7e2f7f798f2e3e728ac836346a7 1146 Pfam PF07971 Glycosyl hydrolase family 92 482 999 9.9E-146 T 23-04-2016 IPR012939 Glycosyl hydrolase family 92 DC74_RS29710 e47cf7e2f7f798f2e3e728ac836346a7 1146 PANTHER PTHR12143:SF19 243 1005 1.5E-225 T 23-04-2016 DC74_RS29710 e47cf7e2f7f798f2e3e728ac836346a7 1146 SUPERFAMILY SSF48208 502 980 3.74E-13 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 DC74_RS29710 e47cf7e2f7f798f2e3e728ac836346a7 1146 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 277 1002 5.3E-147 T 23-04-2016 IPR005887 Alpha-1,2-mannosidase, putative KEGG: 00130+3.2.1.-|KEGG: 00531+3.2.1.- DC74_RS29710 e47cf7e2f7f798f2e3e728ac836346a7 1146 PANTHER PTHR12143 243 1005 1.5E-225 T 23-04-2016 DC74_RS29710 e47cf7e2f7f798f2e3e728ac836346a7 1146 Gene3D G3DSA:1.20.1050.60 599 686 4.1E-29 T 23-04-2016 DC74_RS25065 a2ea3dbb0c2a61c9f1f14fc6651ec4bb 145 SUPERFAMILY SSF110857 1 119 1.23E-14 T 23-04-2016 IPR013024 Butirosin biosynthesis, BtrG-like DC74_RS25065 a2ea3dbb0c2a61c9f1f14fc6651ec4bb 145 Gene3D G3DSA:3.10.490.10 1 145 9.2E-46 T 23-04-2016 IPR013024 Butirosin biosynthesis, BtrG-like DC74_RS25065 a2ea3dbb0c2a61c9f1f14fc6651ec4bb 145 PANTHER PTHR12935 1 145 2.5E-42 T 23-04-2016 IPR017939 Gamma-glutamylcyclotransferase GO:0003839|GO:0006750 KEGG: 00480+2.3.2.4|MetaCyc: PWY-4041 DC74_RS25065 a2ea3dbb0c2a61c9f1f14fc6651ec4bb 145 Pfam PF13772 AIG2-like family 60 138 6.2E-20 T 23-04-2016 DC74_RS02135 d450b6f905fa7d2fde5e879a0d972fc8 832 Gene3D G3DSA:2.160.10.10 171 322 1.9E-17 T 23-04-2016 DC74_RS02135 d450b6f905fa7d2fde5e879a0d972fc8 832 SUPERFAMILY SSF51161 707 811 9.56E-18 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS02135 d450b6f905fa7d2fde5e879a0d972fc8 832 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 765 790 0.041 T 23-04-2016 IPR001451 Hexapeptide repeat DC74_RS02135 d450b6f905fa7d2fde5e879a0d972fc8 832 Pfam PF00550 Phosphopantetheine attachment site 18 82 4.6E-8 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS02135 d450b6f905fa7d2fde5e879a0d972fc8 832 Gene3D G3DSA:2.160.10.10 715 811 1.3E-22 T 23-04-2016 DC74_RS02135 d450b6f905fa7d2fde5e879a0d972fc8 832 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 112 811 6.4E-237 T 23-04-2016 IPR012728 Non-ribosomal peptide synthetase, C-terminal DC74_RS02135 d450b6f905fa7d2fde5e879a0d972fc8 832 SUPERFAMILY SSF51161 212 323 9.56E-12 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS02135 d450b6f905fa7d2fde5e879a0d972fc8 832 SUPERFAMILY SSF47336 14 103 5.1E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS02135 d450b6f905fa7d2fde5e879a0d972fc8 832 Gene3D G3DSA:1.10.1200.10 5 87 2.9E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS21335 5620e0590ebd0412373f9a677df8af33 254 PANTHER PTHR10108 1 238 1.6E-75 T 23-04-2016 DC74_RS21335 5620e0590ebd0412373f9a677df8af33 254 SUPERFAMILY SSF53335 37 252 3.48E-20 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS21335 5620e0590ebd0412373f9a677df8af33 254 PANTHER PTHR10108:SF746 1 238 1.6E-75 T 23-04-2016 DC74_RS21335 5620e0590ebd0412373f9a677df8af33 254 Gene3D G3DSA:3.40.50.150 49 252 6.3E-21 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS21335 5620e0590ebd0412373f9a677df8af33 254 Pfam PF08241 Methyltransferase domain 53 139 4.8E-7 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS34950 955ab84449ece1146edf6f6680d9167c 339 Pfam PF06259 Alpha/beta hydrolase 99 264 6.3E-46 T 23-04-2016 IPR010427 Protein of unknown function DUF1023 DC74_RS34950 955ab84449ece1146edf6f6680d9167c 339 SUPERFAMILY SSF53474 115 253 4.29E-10 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34950 955ab84449ece1146edf6f6680d9167c 339 Gene3D G3DSA:3.40.50.1820 88 106 1.1E-7 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34950 955ab84449ece1146edf6f6680d9167c 339 Gene3D G3DSA:3.40.50.1820 178 284 1.1E-7 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05780 7e2ea13558cd231fb0e958890772ab9c 388 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 197 385 5.9E-32 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS05780 7e2ea13558cd231fb0e958890772ab9c 388 PANTHER PTHR21021 118 385 1.1E-47 T 23-04-2016 DC74_RS05780 7e2ea13558cd231fb0e958890772ab9c 388 PANTHER PTHR21021:SF22 118 385 1.1E-47 T 23-04-2016 DC74_RS05780 7e2ea13558cd231fb0e958890772ab9c 388 SMART SM00331 170 385 3.8E-13 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS05780 7e2ea13558cd231fb0e958890772ab9c 388 SUPERFAMILY SSF81606 186 384 4.19E-11 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS05780 7e2ea13558cd231fb0e958890772ab9c 388 Gene3D G3DSA:3.60.40.10 298 384 1.5E-5 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS31885 f7a7b0f48e3ff405ca9ac59cb0122324 213 Gene3D G3DSA:3.40.630.30 10 174 5.7E-43 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31885 f7a7b0f48e3ff405ca9ac59cb0122324 213 SUPERFAMILY SSF55729 9 174 5.32E-35 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31885 f7a7b0f48e3ff405ca9ac59cb0122324 213 PANTHER PTHR13256:SF24 10 197 9.7E-54 T 23-04-2016 DC74_RS31885 f7a7b0f48e3ff405ca9ac59cb0122324 213 PANTHER PTHR13256 10 197 9.7E-54 T 23-04-2016 DC74_RS31885 f7a7b0f48e3ff405ca9ac59cb0122324 213 Pfam PF13302 Acetyltransferase (GNAT) domain 13 150 1.3E-19 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS36015 94b3e92c548894dfa68608409e418844 425 SUPERFAMILY SSF142764 5 412 4.18E-75 T 23-04-2016 DC74_RS36015 94b3e92c548894dfa68608409e418844 425 Pfam PF07005 Putative sugar-binding N-terminal domain 5 234 1.7E-51 T 23-04-2016 IPR010737 Putative sugar-binding, N-terminal domain DC74_RS36015 94b3e92c548894dfa68608409e418844 425 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 250 404 6.4E-21 T 23-04-2016 IPR031475 Putative nucleotide-binding C-terminal domain DC74_RS25715 f35c5b05b6b068df4ca465e8256c14ec 460 Gene3D G3DSA:3.30.200.20 7 162 1.3E-16 T 23-04-2016 DC74_RS25715 f35c5b05b6b068df4ca465e8256c14ec 460 SMART SM00220 16 291 1.1E-23 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS25715 f35c5b05b6b068df4ca465e8256c14ec 460 SUPERFAMILY SSF56112 12 288 2.97E-45 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS25715 f35c5b05b6b068df4ca465e8256c14ec 460 Gene3D G3DSA:1.10.510.10 163 286 1.1E-21 T 23-04-2016 DC74_RS25715 f35c5b05b6b068df4ca465e8256c14ec 460 Pfam PF00069 Protein kinase domain 65 249 6.1E-22 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS25715 f35c5b05b6b068df4ca465e8256c14ec 460 PANTHER PTHR24362:SF160 62 281 1.1E-50 T 23-04-2016 DC74_RS25715 f35c5b05b6b068df4ca465e8256c14ec 460 PANTHER PTHR24362:SF160 11 38 1.1E-50 T 23-04-2016 DC74_RS25715 f35c5b05b6b068df4ca465e8256c14ec 460 PANTHER PTHR24362 62 281 1.1E-50 T 23-04-2016 DC74_RS25715 f35c5b05b6b068df4ca465e8256c14ec 460 PANTHER PTHR24362 11 38 1.1E-50 T 23-04-2016 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 Gene3D G3DSA:2.40.37.10 253 388 8.2E-18 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 PANTHER PTHR11482:SF6 21 387 1.7E-98 T 23-04-2016 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 PANTHER PTHR11482 21 387 1.7E-98 T 23-04-2016 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 PRINTS PR01182 Ornithine decarboxylase signature 43 70 1.1E-11 T 23-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 PRINTS PR01182 Ornithine decarboxylase signature 328 338 1.1E-11 T 23-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 PRINTS PR01182 Ornithine decarboxylase signature 87 111 1.1E-11 T 23-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 PRINTS PR01182 Ornithine decarboxylase signature 17 41 1.1E-11 T 23-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 PRINTS PR01182 Ornithine decarboxylase signature 117 139 1.1E-11 T 23-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 258 277 2.7E-12 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 65 77 2.7E-12 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 45 63 2.7E-12 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 167 180 2.7E-12 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 45 63 - T 23-04-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 28 268 4.9E-44 T 23-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 Gene3D G3DSA:3.20.20.10 27 252 2.3E-55 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 282 381 5.0E-10 T 23-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 SUPERFAMILY SSF51419 23 270 2.06E-57 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS06370 fd5e2d697330e5157ba969d6b0d185a5 412 SUPERFAMILY SSF50621 250 389 6.91E-21 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS23675 ccd6ef417386d2f40aa89114e612fb5b 365 Gene3D G3DSA:1.10.3470.10 33 355 7.5E-87 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS23675 ccd6ef417386d2f40aa89114e612fb5b 365 Pfam PF01032 FecCD transport family 47 352 9.9E-80 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS23675 ccd6ef417386d2f40aa89114e612fb5b 365 PANTHER PTHR30472 15 358 5.5E-99 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS23675 ccd6ef417386d2f40aa89114e612fb5b 365 PANTHER PTHR30472:SF24 15 358 5.5E-99 T 23-04-2016 DC74_RS23675 ccd6ef417386d2f40aa89114e612fb5b 365 SUPERFAMILY SSF81345 30 352 9.55E-69 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS21530 b507df2ed088b7a08493ad1b1dc167f7 280 PANTHER PTHR34406 49 280 4.7E-63 T 23-04-2016 DC74_RS21530 b507df2ed088b7a08493ad1b1dc167f7 280 SUPERFAMILY SSF49464 11 92 3.06E-6 T 23-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain DC74_RS21530 b507df2ed088b7a08493ad1b1dc167f7 280 PANTHER PTHR34406:SF1 49 280 4.7E-63 T 23-04-2016 DC74_RS21530 b507df2ed088b7a08493ad1b1dc167f7 280 SMART SM00867 104 272 2.8E-65 T 23-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like DC74_RS21530 b507df2ed088b7a08493ad1b1dc167f7 280 SUPERFAMILY SSF101874 103 274 2.35E-51 T 23-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like DC74_RS21530 b507df2ed088b7a08493ad1b1dc167f7 280 Pfam PF04264 YceI-like domain 105 271 9.0E-39 T 23-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like DC74_RS21530 b507df2ed088b7a08493ad1b1dc167f7 280 Gene3D G3DSA:2.40.128.110 104 274 2.9E-55 T 23-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like DC74_RS21530 b507df2ed088b7a08493ad1b1dc167f7 280 Gene3D G3DSA:2.60.40.1120 10 95 2.7E-6 T 23-04-2016 IPR014766 Carboxypeptidase, regulatory domain DC74_RS39040 d37733dd33f54f5411faa3f9b6ecb95d 197 SMART SM00530 22 77 2.9E-14 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS39040 d37733dd33f54f5411faa3f9b6ecb95d 197 SUPERFAMILY SSF51182 62 195 2.32E-31 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS39040 d37733dd33f54f5411faa3f9b6ecb95d 197 Pfam PF01381 Helix-turn-helix 23 75 1.2E-14 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS39040 d37733dd33f54f5411faa3f9b6ecb95d 197 SUPERFAMILY SSF47413 18 84 5.63E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS39040 d37733dd33f54f5411faa3f9b6ecb95d 197 Gene3D G3DSA:2.60.120.10 73 195 5.4E-29 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS39040 d37733dd33f54f5411faa3f9b6ecb95d 197 Pfam PF07883 Cupin domain 122 190 7.6E-19 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS39040 d37733dd33f54f5411faa3f9b6ecb95d 197 PANTHER PTHR10245 16 194 2.6E-40 T 23-04-2016 DC74_RS39040 d37733dd33f54f5411faa3f9b6ecb95d 197 Gene3D G3DSA:1.10.260.40 15 72 1.1E-21 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS39040 d37733dd33f54f5411faa3f9b6ecb95d 197 PANTHER PTHR10245:SF53 16 194 2.6E-40 T 23-04-2016 DC74_RS18740 d35654293dc2e94d70aeab4558b9f5eb 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.1E-47 T 23-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 DC74_RS18740 d35654293dc2e94d70aeab4558b9f5eb 102 PANTHER PTHR11700 1 102 3.8E-53 T 23-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 DC74_RS18740 d35654293dc2e94d70aeab4558b9f5eb 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.897 T 23-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 DC74_RS18740 d35654293dc2e94d70aeab4558b9f5eb 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 7.9E-37 T 23-04-2016 IPR027486 Ribosomal protein S10 domain DC74_RS18740 d35654293dc2e94d70aeab4558b9f5eb 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 23-04-2016 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18740 d35654293dc2e94d70aeab4558b9f5eb 102 Gene3D G3DSA:3.30.70.600 4 102 5.6E-45 T 23-04-2016 IPR027486 Ribosomal protein S10 domain DC74_RS18740 d35654293dc2e94d70aeab4558b9f5eb 102 SMART SM01403 7 101 3.5E-59 T 23-04-2016 IPR027486 Ribosomal protein S10 domain DC74_RS18740 d35654293dc2e94d70aeab4558b9f5eb 102 SUPERFAMILY SSF54999 5 102 1.02E-38 T 23-04-2016 IPR027486 Ribosomal protein S10 domain DC74_RS18740 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.6E-21 T 23-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 DC74_RS18740 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.6E-21 T 23-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 DC74_RS18740 d35654293dc2e94d70aeab4558b9f5eb 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.6E-21 T 23-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Gene3D G3DSA:3.30.300.30 873 991 5.5E-31 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Gene3D G3DSA:3.30.300.30 1947 2062 1.3E-40 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Gene3D G3DSA:3.40.50.980 1540 1653 3.2E-46 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Gene3D G3DSA:3.40.50.980 468 626 1.3E-44 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Gene3D G3DSA:3.40.50.980 1688 1724 3.2E-46 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2083 2098 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 PANTHER PTHR24095:SF173 1 2034 0.0 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Gene3D G3DSA:1.10.1200.10 992 1052 8.3E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Gene3D G3DSA:1.10.1200.10 2063 2125 1.6E-23 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Gene3D G3DSA:3.40.50.980 627 784 3.1E-29 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1703 1714 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 PANTHER PTHR24095 1 2034 0.0 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 SUPERFAMILY SSF52777 195 444 3.45E-48 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 SUPERFAMILY SSF52777 1270 1514 1.56E-49 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 SUPERFAMILY SSF52777 1087 1284 1.45E-43 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Gene3D G3DSA:3.40.50.980 1725 1863 7.5E-37 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 496 902 2.2E-118 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1567 1975 2.9E-127 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Gene3D G3DSA:2.30.38.10 1864 1940 1.3E-24 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Gene3D G3DSA:2.30.38.10 788 867 1.5E-23 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 SUPERFAMILY SSF47336 978 1048 6.54E-16 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 SUPERFAMILY SSF56801 1505 2071 1.44E-152 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 SUPERFAMILY SSF52777 5 209 1.45E-42 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Pfam PF00550 Phosphopantetheine attachment site 2060 2121 3.0E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Pfam PF00550 Phosphopantetheine attachment site 988 1047 4.5E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 SUPERFAMILY SSF47336 2052 2120 4.71E-16 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 SMART SM00823 Phosphopantetheine attachment site 986 1054 8.9E-4 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 SMART SM00823 Phosphopantetheine attachment site 2059 2127 4.0E-6 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Pfam PF00668 Condensation domain 1088 1381 3.7E-57 T 23-04-2016 IPR001242 Condensation domain DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Pfam PF00668 Condensation domain 8 309 9.0E-54 T 23-04-2016 IPR001242 Condensation domain DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 ProSitePatterns PS00455 Putative AMP-binding domain signature. 618 629 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Pfam PF00501 AMP-binding enzyme 475 878 1.1E-84 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Pfam PF00501 AMP-binding enzyme 1546 1951 6.2E-93 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 SUPERFAMILY SSF56801 435 998 4.06E-132 T 23-04-2016 DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Pfam PF13193 AMP-binding enzyme C-terminal domain 1959 2034 3.1E-14 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 Pfam PF13193 AMP-binding enzyme C-terminal domain 886 961 1.7E-7 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS29455 67f648b09e96d3977a7a3c1858dc6804 2158 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1010 1025 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 SUPERFAMILY SSF52540 284 551 8.71E-31 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 PRINTS PR00364 Disease resistance protein signature 484 498 6.3E-8 T 23-04-2016 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 PRINTS PR00364 Disease resistance protein signature 399 413 6.3E-8 T 23-04-2016 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 PRINTS PR00364 Disease resistance protein signature 320 335 6.3E-8 T 23-04-2016 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 SMART SM00862 24 103 6.4E-15 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 Gene3D G3DSA:1.25.40.10 751 909 1.2E-21 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 Pfam PF00486 Transcriptional regulatory protein, C terminal 33 103 7.2E-11 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 Pfam PF13424 Tetratricopeptide repeat 698 760 1.6E-7 T 23-04-2016 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 Pfam PF13424 Tetratricopeptide repeat 814 878 2.8E-8 T 23-04-2016 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 SMART SM00028 769 802 56.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 SMART SM00028 115 148 230.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 SMART SM00028 849 882 3.5 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 SMART SM00028 809 842 3.8 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 SMART SM00028 729 762 2.4 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 Pfam PF00931 NB-ARC domain 317 556 3.2E-11 T 23-04-2016 IPR002182 NB-ARC GO:0043531 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 SUPERFAMILY SSF48452 107 266 1.42E-27 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 SUPERFAMILY SSF48452 699 798 1.21E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 Pfam PF03704 Bacterial transcriptional activator domain 110 254 2.7E-31 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 SUPERFAMILY SSF46894 11 103 2.15E-13 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 Gene3D G3DSA:1.10.10.10 19 105 7.5E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 SMART SM01043 110 254 1.8E-41 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 Gene3D G3DSA:3.40.50.300 325 418 5.5E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 PANTHER PTHR22845:SF4 153 633 2.0E-72 T 23-04-2016 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 Gene3D G3DSA:1.25.40.10 725 750 5.3E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 Gene3D G3DSA:1.25.40.10 120 144 5.3E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 Gene3D G3DSA:1.25.40.10 200 233 5.3E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 PANTHER PTHR22845 153 633 2.0E-72 T 23-04-2016 DC74_RS01605 4dc1231f4e2b053a9136dd6e0b8db19b 985 SUPERFAMILY SSF48452 762 911 4.49E-17 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1065 1080 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Gene3D G3DSA:3.40.50.980 647 800 1.1E-23 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 SUPERFAMILY SSF52777 15 199 4.82E-42 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Pfam PF00668 Condensation domain 1175 1464 1.7E-25 T 23-04-2016 IPR001242 Condensation domain DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Pfam PF00668 Condensation domain 11 316 8.0E-58 T 23-04-2016 IPR001242 Condensation domain DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Pfam PF00668 Condensation domain 1642 1941 4.7E-60 T 23-04-2016 IPR001242 Condensation domain DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Pfam PF00501 AMP-binding enzyme 491 890 2.6E-81 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 SUPERFAMILY SSF52777 1826 2066 1.33E-50 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Gene3D G3DSA:1.10.1200.10 2073 2149 2.3E-16 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Gene3D G3DSA:1.10.1200.10 1034 1109 1.7E-20 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 PANTHER PTHR24095:SF173 1015 1096 0.0 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 PANTHER PTHR24095:SF173 388 983 0.0 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 PANTHER PTHR24095 1617 1991 0.0 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 SUPERFAMILY SSF52777 1163 1358 8.23E-27 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 PANTHER PTHR24095 1 370 0.0 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 513 914 4.8E-119 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 SUPERFAMILY SSF47336 1040 1106 2.88E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 ProSitePatterns PS00455 Putative AMP-binding domain signature. 639 650 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Gene3D G3DSA:3.40.50.980 486 646 1.9E-46 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 SUPERFAMILY SSF47336 2084 2149 3.4E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 PANTHER PTHR24095:SF173 1 370 0.0 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 SMART SM00823 Phosphopantetheine attachment site 2084 2150 6.9E-4 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 SMART SM00823 Phosphopantetheine attachment site 1041 1109 4.0E-4 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 PANTHER PTHR24095:SF173 1617 1991 0.0 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 PANTHER PTHR24095 388 983 0.0 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 SUPERFAMILY SSF52777 1347 1614 1.33E-28 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1481 1620 7.9E-28 T 23-04-2016 IPR010060 Non-ribosomal peptide synthase DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 SUPERFAMILY SSF52777 201 450 9.64E-47 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Gene3D G3DSA:2.30.38.10 801 879 1.5E-24 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Gene3D G3DSA:3.30.300.30 884 982 1.7E-35 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 SMART SM01294 1042 1105 0.0016 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 PANTHER PTHR24095 1015 1096 0.0 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 SUPERFAMILY SSF56801 448 982 1.57E-135 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 SUPERFAMILY SSF52777 1640 1841 2.82E-42 T 23-04-2016 DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Pfam PF13193 AMP-binding enzyme C-terminal domain 898 973 4.0E-13 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Pfam PF00550 Phosphopantetheine attachment site 2086 2148 3.9E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29440 512caea35c838ebfae1f5f037adfcb26 2150 Pfam PF00550 Phosphopantetheine attachment site 1043 1105 2.7E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS19160 f7bfcbfe757cace6afaad69fce2353fa 120 Gene3D G3DSA:1.10.287.1060 7 95 3.8E-14 T 23-04-2016 DC74_RS19160 f7bfcbfe757cace6afaad69fce2353fa 120 Pfam PF06013 Proteins of 100 residues with WXG 7 83 1.0E-10 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS19160 f7bfcbfe757cace6afaad69fce2353fa 120 SUPERFAMILY SSF140453 8 97 1.31E-13 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 PIRSF PIRSF001438 1 311 4.8E-95 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 PANTHER PTHR11557 5 309 1.1E-113 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 230 298 1.6E-10 T 23-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 233 249 - T 23-04-2016 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 Gene3D G3DSA:3.40.190.10 113 201 5.8E-31 T 23-04-2016 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 Gene3D G3DSA:3.30.160.40 223 307 2.5E-16 T 23-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 PRINTS PR00151 Porphobilinogen deaminase signature 126 143 1.6E-22 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 PRINTS PR00151 Porphobilinogen deaminase signature 145 162 1.6E-22 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 1.6E-22 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 1.6E-22 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 PRINTS PR00151 Porphobilinogen deaminase signature 232 249 1.6E-22 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 6 300 32.503 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 SUPERFAMILY SSF53850 6 219 6.83E-64 T 23-04-2016 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 7 214 2.8E-60 T 23-04-2016 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 SUPERFAMILY SSF54782 223 309 4.97E-18 T 23-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 Gene3D G3DSA:3.40.190.10 6 112 6.1E-35 T 23-04-2016 DC74_RS04355 7549f92bd35ba4b0ced987669f04d49b 311 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 7 300 1.1E-95 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS27245 baa8606c96d77def363c1b996bf6bc13 322 PANTHER PTHR10438 283 304 2.1E-42 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DC74_RS27245 baa8606c96d77def363c1b996bf6bc13 322 PANTHER PTHR10438 26 155 2.1E-42 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DC74_RS27245 baa8606c96d77def363c1b996bf6bc13 322 Pfam PF14559 Tetratricopeptide repeat 196 231 1.2E-6 T 23-04-2016 DC74_RS27245 baa8606c96d77def363c1b996bf6bc13 322 ProSitePatterns PS00194 Thioredoxin family active site. 70 88 - T 23-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 DC74_RS27245 baa8606c96d77def363c1b996bf6bc13 322 Gene3D G3DSA:1.25.40.10 241 322 9.6E-13 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS27245 baa8606c96d77def363c1b996bf6bc13 322 Gene3D G3DSA:1.25.40.10 185 229 5.3E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS27245 baa8606c96d77def363c1b996bf6bc13 322 Pfam PF00085 Thioredoxin 50 151 1.4E-23 T 23-04-2016 IPR013766 Thioredoxin domain GO:0045454 DC74_RS27245 baa8606c96d77def363c1b996bf6bc13 322 Gene3D G3DSA:3.40.30.10 48 153 1.5E-29 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS27245 baa8606c96d77def363c1b996bf6bc13 322 PANTHER PTHR10438:SF282 283 304 2.1E-42 T 23-04-2016 DC74_RS27245 baa8606c96d77def363c1b996bf6bc13 322 PANTHER PTHR10438:SF282 26 155 2.1E-42 T 23-04-2016 DC74_RS27245 baa8606c96d77def363c1b996bf6bc13 322 SUPERFAMILY SSF52833 46 153 2.78E-31 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS27245 baa8606c96d77def363c1b996bf6bc13 322 Pfam PF14561 Tetratricopeptide repeat 237 322 3.5E-23 T 23-04-2016 DC74_RS21325 8f09fe872f5c7d5b019c36d0a919536c 172 SMART SM00347 50 153 6.5E-20 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21325 8f09fe872f5c7d5b019c36d0a919536c 172 Gene3D G3DSA:1.10.10.10 17 168 1.4E-39 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21325 8f09fe872f5c7d5b019c36d0a919536c 172 SUPERFAMILY SSF46785 19 167 1.22E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21325 8f09fe872f5c7d5b019c36d0a919536c 172 ProSitePatterns PS01117 MarR-type HTH domain signature. 92 126 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS21325 8f09fe872f5c7d5b019c36d0a919536c 172 PANTHER PTHR33164:SF4 2 168 3.5E-32 T 23-04-2016 DC74_RS21325 8f09fe872f5c7d5b019c36d0a919536c 172 PANTHER PTHR33164 2 168 3.5E-32 T 23-04-2016 DC74_RS21325 8f09fe872f5c7d5b019c36d0a919536c 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 109 1.5E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21325 8f09fe872f5c7d5b019c36d0a919536c 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 143 163 1.5E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21325 8f09fe872f5c7d5b019c36d0a919536c 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 129 1.5E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21325 8f09fe872f5c7d5b019c36d0a919536c 172 Pfam PF12802 MarR family 55 117 4.5E-13 T 23-04-2016 DC74_RS33140 19c09f59a35982969e4b54c26775440f 223 Pfam PF01965 DJ-1/PfpI family 2 161 1.6E-24 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS33140 19c09f59a35982969e4b54c26775440f 223 Gene3D G3DSA:3.40.50.880 2 207 5.0E-64 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS33140 19c09f59a35982969e4b54c26775440f 223 SUPERFAMILY SSF52317 2 183 1.87E-44 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS33140 19c09f59a35982969e4b54c26775440f 223 PANTHER PTHR11019:SF131 1 187 1.3E-68 T 23-04-2016 DC74_RS33140 19c09f59a35982969e4b54c26775440f 223 PANTHER PTHR11019 1 187 1.3E-68 T 23-04-2016 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.3E-24 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.3E-24 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.3E-24 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.3E-24 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.3E-24 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 397 4.8E-223 T 23-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 23-04-2016 IPR031157 Tr-type G domain, conserved site DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 SUPERFAMILY SSF50447 207 304 1.57E-30 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 SUPERFAMILY SSF52540 6 221 9.06E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 PANTHER PTHR23115 1 397 3.1E-249 T 23-04-2016 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 Gene3D G3DSA:2.40.30.10 214 301 7.4E-37 T 23-04-2016 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 Gene3D G3DSA:2.40.30.10 303 395 1.8E-46 T 23-04-2016 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 5.2E-17 T 23-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 Gene3D G3DSA:3.40.50.300 5 213 5.0E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 5.3E-59 T 23-04-2016 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 1.2E-33 T 23-04-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.499 T 23-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 2.2E-13 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 PANTHER PTHR23115:SF112 1 397 3.1E-249 T 23-04-2016 DC74_RS18745 7cd943689c3586c1e672c0060c920912 397 SUPERFAMILY SSF50465 305 397 8.06E-36 T 23-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 242 7.1E-57 T 23-04-2016 DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.7E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.7E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.7E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.7E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.7E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 Gene3D G3DSA:3.40.50.720 2 245 3.7E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 SUPERFAMILY SSF51735 1 245 1.92E-74 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 PANTHER PTHR24322 153 185 2.0E-52 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 PANTHER PTHR24322 12 137 2.0E-52 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.7E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.7E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00920 aca11460acdd6ebba2319a3848f183ca 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.7E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS12390 79f731feb4814bc9ff68c9a5465d34a5 377 SUPERFAMILY SSF53383 27 364 1.77E-78 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS12390 79f731feb4814bc9ff68c9a5465d34a5 377 PANTHER PTHR11751:SF398 8 372 5.7E-110 T 23-04-2016 DC74_RS12390 79f731feb4814bc9ff68c9a5465d34a5 377 PANTHER PTHR11751 8 372 5.7E-110 T 23-04-2016 DC74_RS12390 79f731feb4814bc9ff68c9a5465d34a5 377 Gene3D G3DSA:3.40.640.10 45 273 7.8E-66 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS12390 79f731feb4814bc9ff68c9a5465d34a5 377 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 230 239 - T 23-04-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 DC74_RS12390 79f731feb4814bc9ff68c9a5465d34a5 377 Pfam PF00155 Aminotransferase class I and II 28 363 2.2E-64 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS12390 79f731feb4814bc9ff68c9a5465d34a5 377 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 10 365 1.0E-97 T 23-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 DC74_RS12390 79f731feb4814bc9ff68c9a5465d34a5 377 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 367 54.636 T 23-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 DC74_RS12390 79f731feb4814bc9ff68c9a5465d34a5 377 Gene3D G3DSA:3.90.1150.10 274 369 9.8E-20 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS08940 1383604754927379cdb2d3c603f9f2d8 386 SUPERFAMILY SSF51679 2 370 1.03E-71 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS08940 1383604754927379cdb2d3c603f9f2d8 386 Pfam PF00296 Luciferase-like monooxygenase 21 340 1.2E-47 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS08940 1383604754927379cdb2d3c603f9f2d8 386 PANTHER PTHR30137 21 293 3.0E-53 T 23-04-2016 DC74_RS08940 1383604754927379cdb2d3c603f9f2d8 386 PANTHER PTHR30137 314 381 3.0E-53 T 23-04-2016 DC74_RS08940 1383604754927379cdb2d3c603f9f2d8 386 Gene3D G3DSA:3.20.20.30 316 371 2.3E-89 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS08940 1383604754927379cdb2d3c603f9f2d8 386 Gene3D G3DSA:3.20.20.30 1 278 2.3E-89 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS11795 e36e73e8272d70d2d999f7bdd393ba7e 268 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 248 9.6E-74 T 23-04-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 DC74_RS11795 e36e73e8272d70d2d999f7bdd393ba7e 268 PANTHER PTHR11054 2 263 2.3E-73 T 23-04-2016 DC74_RS11795 e36e73e8272d70d2d999f7bdd393ba7e 268 Gene3D G3DSA:3.40.50.1360 4 258 2.9E-73 T 23-04-2016 DC74_RS11795 e36e73e8272d70d2d999f7bdd393ba7e 268 SUPERFAMILY SSF100950 6 263 1.02E-62 T 23-04-2016 DC74_RS11795 e36e73e8272d70d2d999f7bdd393ba7e 268 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 8 258 7.2E-75 T 23-04-2016 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31|UniPathway: UPA00115 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 33 537 1.1E-214 T 23-04-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 42 484 5.4E-146 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PANTHER PTHR10422:SF6 18 563 2.4E-295 T 23-04-2016 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 181 199 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 328 349 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 32 57 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 239 260 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 149 161 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 260 281 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 363 381 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 391 410 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 306 321 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 441 462 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 79 102 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 210 229 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PRINTS PR01165 Cytochrome c oxidase subunit I signature 106 130 3.2E-103 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 Gene3D G3DSA:1.20.210.10 30 550 3.7E-194 T 23-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 SUPERFAMILY SSF81442 31 540 3.53E-176 T 23-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 PANTHER PTHR10422 18 563 2.4E-295 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS12920 be479507faa12562140a34259aeb1e7d 576 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 262 316 - T 23-04-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 PANTHER PTHR26402 1 195 2.1E-42 T 23-04-2016 DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 8.6E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 179 8.6E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 8.6E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 SMART SM00448 1 95 0.0026 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 SUPERFAMILY SSF52172 12 107 2.42E-17 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 Pfam PF00072 Response regulator receiver domain 13 95 1.1E-13 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 191 1.1E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 SMART SM00421 134 191 7.3E-17 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 PANTHER PTHR26402:SF151 1 195 2.1E-42 T 23-04-2016 DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 Gene3D G3DSA:3.40.50.2300 14 136 3.3E-20 T 23-04-2016 DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 Gene3D G3DSA:1.10.10.10 137 195 3.4E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32165 84de3e52aa62feec0dfcfc33ce7998fc 207 SUPERFAMILY SSF46894 125 195 4.76E-17 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS13875 70bb61d65510f3308deab3ec1a9c9e88 151 SUPERFAMILY SSF55729 2 139 9.76E-23 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS13875 70bb61d65510f3308deab3ec1a9c9e88 151 Gene3D G3DSA:3.40.630.30 3 146 3.8E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS13875 70bb61d65510f3308deab3ec1a9c9e88 151 PANTHER PTHR23091:SF264 3 133 7.5E-12 T 23-04-2016 DC74_RS13875 70bb61d65510f3308deab3ec1a9c9e88 151 PANTHER PTHR23091 3 133 7.5E-12 T 23-04-2016 DC74_RS13875 70bb61d65510f3308deab3ec1a9c9e88 151 Pfam PF13673 Acetyltransferase (GNAT) domain 49 129 2.8E-13 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS39735 35905f3368876e0d30da5c43cc499cec 394 PIRSF PIRSF016578 1 390 2.3E-38 T 23-04-2016 DC74_RS39735 35905f3368876e0d30da5c43cc499cec 394 Gene3D G3DSA:2.40.110.10 131 211 5.1E-23 T 23-04-2016 DC74_RS39735 35905f3368876e0d30da5c43cc499cec 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 210 6.6E-13 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS39735 35905f3368876e0d30da5c43cc499cec 394 PANTHER PTHR10909:SF300 8 378 1.3E-112 T 23-04-2016 DC74_RS39735 35905f3368876e0d30da5c43cc499cec 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 237 369 3.1E-19 T 23-04-2016 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain DC74_RS39735 35905f3368876e0d30da5c43cc499cec 394 TIGRFAM TIGR04022 sulfur_SfnB: sulfur acquisition oxidoreductase, SfnB family 3 393 1.3E-166 T 23-04-2016 IPR023922 Sulphate-starvation-induced SfnB DC74_RS39735 35905f3368876e0d30da5c43cc499cec 394 SUPERFAMILY SSF47203 232 391 6.77E-24 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS39735 35905f3368876e0d30da5c43cc499cec 394 Gene3D G3DSA:1.20.140.10 212 391 3.7E-55 T 23-04-2016 DC74_RS39735 35905f3368876e0d30da5c43cc499cec 394 Gene3D G3DSA:1.10.540.10 2 109 2.4E-26 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS39735 35905f3368876e0d30da5c43cc499cec 394 SUPERFAMILY SSF56645 15 219 3.4E-50 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS39735 35905f3368876e0d30da5c43cc499cec 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 115 3.8E-11 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS39735 35905f3368876e0d30da5c43cc499cec 394 PANTHER PTHR10909 8 378 1.3E-112 T 23-04-2016 DC74_RS22665 587c58e464cd24f87bab5f92757a6132 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 161 8.5E-25 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS22665 587c58e464cd24f87bab5f92757a6132 181 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 36 67 - T 23-04-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS22665 587c58e464cd24f87bab5f92757a6132 181 SUPERFAMILY SSF88659 99 162 1.81E-16 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS22665 587c58e464cd24f87bab5f92757a6132 181 Gene3D G3DSA:1.10.10.10 99 163 1.9E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22665 587c58e464cd24f87bab5f92757a6132 181 Gene3D G3DSA:1.10.1740.10 9 81 8.0E-14 T 23-04-2016 DC74_RS22665 587c58e464cd24f87bab5f92757a6132 181 Pfam PF04542 Sigma-70 region 2 18 80 6.9E-8 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS22665 587c58e464cd24f87bab5f92757a6132 181 SUPERFAMILY SSF88946 6 77 1.92E-12 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS22665 587c58e464cd24f87bab5f92757a6132 181 PANTHER PTHR30173 11 178 6.2E-27 T 23-04-2016 DC74_RS22665 587c58e464cd24f87bab5f92757a6132 181 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 7 164 5.4E-61 T 23-04-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 DC74_RS22665 587c58e464cd24f87bab5f92757a6132 181 Pfam PF08281 Sigma-70, region 4 106 157 1.6E-16 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS10935 924b35572619e956beb48416b19e9402 827 Pfam PF00672 HAMP domain 330 412 1.1E-6 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS10935 924b35572619e956beb48416b19e9402 827 PANTHER PTHR24423 5 28 9.1E-28 T 23-04-2016 DC74_RS10935 924b35572619e956beb48416b19e9402 827 PANTHER PTHR24423 397 793 9.1E-28 T 23-04-2016 DC74_RS10935 924b35572619e956beb48416b19e9402 827 Pfam PF08376 Nitrate and nitrite sensing 76 309 1.0E-39 T 23-04-2016 IPR013587 Nitrate/nitrite sensing protein DC74_RS10935 924b35572619e956beb48416b19e9402 827 Gene3D G3DSA:3.30.565.10 532 642 8.0E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS10935 924b35572619e956beb48416b19e9402 827 SUPERFAMILY SSF55874 525 637 5.76E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS10935 924b35572619e956beb48416b19e9402 827 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 532 637 3.1E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS10935 924b35572619e956beb48416b19e9402 827 PANTHER PTHR24423:SF523 5 28 9.1E-28 T 23-04-2016 DC74_RS10935 924b35572619e956beb48416b19e9402 827 PANTHER PTHR24423:SF523 397 793 9.1E-28 T 23-04-2016 DC74_RS36230 acba2b8aa54a54b33bf4abe73b1b8d6e 116 ProSitePatterns PS00194 Thioredoxin family active site. 28 46 - T 23-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 DC74_RS36230 acba2b8aa54a54b33bf4abe73b1b8d6e 116 PRINTS PR00421 Thioredoxin family signature 75 86 1.9E-6 T 23-04-2016 DC74_RS36230 acba2b8aa54a54b33bf4abe73b1b8d6e 116 PRINTS PR00421 Thioredoxin family signature 35 44 1.9E-6 T 23-04-2016 DC74_RS36230 acba2b8aa54a54b33bf4abe73b1b8d6e 116 PRINTS PR00421 Thioredoxin family signature 27 35 1.9E-6 T 23-04-2016 DC74_RS36230 acba2b8aa54a54b33bf4abe73b1b8d6e 116 Pfam PF00085 Thioredoxin 8 108 2.9E-29 T 23-04-2016 IPR013766 Thioredoxin domain GO:0045454 DC74_RS36230 acba2b8aa54a54b33bf4abe73b1b8d6e 116 PANTHER PTHR10438 8 114 2.2E-33 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DC74_RS36230 acba2b8aa54a54b33bf4abe73b1b8d6e 116 TIGRFAM TIGR01068 thioredoxin: thioredoxin 12 109 1.4E-29 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DC74_RS36230 acba2b8aa54a54b33bf4abe73b1b8d6e 116 Gene3D G3DSA:3.40.30.10 5 110 4.2E-31 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS36230 acba2b8aa54a54b33bf4abe73b1b8d6e 116 SUPERFAMILY SSF52833 6 112 9.49E-33 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS36230 acba2b8aa54a54b33bf4abe73b1b8d6e 116 PIRSF PIRSF000077 5 111 4.7E-35 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DC74_RS16675 24843c52a1a7cd0c3b44f2c37126968c 399 PANTHER PTHR32060 65 381 2.5E-80 T 23-04-2016 DC74_RS16675 24843c52a1a7cd0c3b44f2c37126968c 399 Gene3D G3DSA:2.30.42.10 116 208 2.3E-18 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS16675 24843c52a1a7cd0c3b44f2c37126968c 399 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 111 173 3.0E-8 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS16675 24843c52a1a7cd0c3b44f2c37126968c 399 SUPERFAMILY SSF52096 81 133 2.65E-47 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS16675 24843c52a1a7cd0c3b44f2c37126968c 399 SUPERFAMILY SSF52096 216 385 2.65E-47 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS16675 24843c52a1a7cd0c3b44f2c37126968c 399 Pfam PF03572 Peptidase family S41 226 379 7.8E-39 T 23-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 DC74_RS16675 24843c52a1a7cd0c3b44f2c37126968c 399 SMART SM00245 195 381 2.0E-39 T 23-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 DC74_RS16675 24843c52a1a7cd0c3b44f2c37126968c 399 SUPERFAMILY SSF50156 98 210 2.73E-15 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS16675 24843c52a1a7cd0c3b44f2c37126968c 399 SMART SM00228 108 195 8.2E-8 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS16675 24843c52a1a7cd0c3b44f2c37126968c 399 Gene3D G3DSA:3.90.226.10 222 385 2.4E-44 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS25675 a27be2d989ccf3e6e4eabdf42996032b 539 Pfam PF05598 Transposase domain (DUF772) 24 96 1.3E-16 T 23-04-2016 IPR008490 Transposase InsH, N-terminal DC74_RS25675 a27be2d989ccf3e6e4eabdf42996032b 539 Pfam PF13751 Transposase DDE domain 375 501 2.6E-27 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS15360 1288746a3899586c7db537aac3976d5d 381 PANTHER PTHR21021 151 381 2.1E-63 T 23-04-2016 DC74_RS15360 1288746a3899586c7db537aac3976d5d 381 PANTHER PTHR21021:SF21 151 381 2.1E-63 T 23-04-2016 DC74_RS15360 1288746a3899586c7db537aac3976d5d 381 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 199 379 2.5E-31 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS15360 1288746a3899586c7db537aac3976d5d 381 SMART SM00331 170 379 8.6E-9 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS00780 4f25bcbe2a7107f1b6a824443c6ef954 316 PANTHER PTHR10108 215 263 2.0E-15 T 23-04-2016 DC74_RS00780 4f25bcbe2a7107f1b6a824443c6ef954 316 PANTHER PTHR10108 3 134 2.0E-15 T 23-04-2016 DC74_RS00780 4f25bcbe2a7107f1b6a824443c6ef954 316 SUPERFAMILY SSF53335 3 131 9.11E-26 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS00780 4f25bcbe2a7107f1b6a824443c6ef954 316 Gene3D G3DSA:3.40.50.150 20 136 6.4E-22 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS00780 4f25bcbe2a7107f1b6a824443c6ef954 316 Pfam PF13847 Methyltransferase domain 23 129 5.2E-16 T 23-04-2016 IPR025714 Methyltransferase domain DC74_RS38260 7f58edb56a7e237aed3731238431c218 240 PANTHER PTHR30055:SF36 12 144 4.6E-31 T 23-04-2016 DC74_RS38260 7f58edb56a7e237aed3731238431c218 240 PANTHER PTHR30055 12 144 4.6E-31 T 23-04-2016 DC74_RS38260 7f58edb56a7e237aed3731238431c218 240 Gene3D G3DSA:1.10.357.10 81 231 1.5E-29 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS38260 7f58edb56a7e237aed3731238431c218 240 Gene3D G3DSA:1.10.10.60 14 80 8.6E-21 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS38260 7f58edb56a7e237aed3731238431c218 240 SUPERFAMILY SSF46689 24 84 1.28E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS38260 7f58edb56a7e237aed3731238431c218 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 76 5.6E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS38260 7f58edb56a7e237aed3731238431c218 240 SUPERFAMILY SSF48498 95 234 1.67E-26 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS38260 7f58edb56a7e237aed3731238431c218 240 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 89 230 2.0E-17 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 13 584 2.7E-129 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 Pfam PF05746 DALR anticodon binding domain 469 584 4.4E-33 T 23-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 Gene3D G3DSA:3.30.1360.70 5 107 4.8E-25 T 23-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 SUPERFAMILY SSF52374 114 461 2.93E-78 T 23-04-2016 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 PRINTS PR01038 Arginyl-tRNA synthetase signature 117 132 3.3E-21 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 PRINTS PR01038 Arginyl-tRNA synthetase signature 312 333 3.3E-21 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 PRINTS PR01038 Arginyl-tRNA synthetase signature 132 148 3.3E-21 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 PRINTS PR01038 Arginyl-tRNA synthetase signature 156 169 3.3E-21 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 88 1.3E-14 T 23-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 Gene3D G3DSA:3.40.50.620 115 461 1.5E-98 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 Pfam PF00750 tRNA synthetases class I (R) 109 454 6.6E-99 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 SMART SM00836 469 584 8.9E-40 T 23-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 SUPERFAMILY SSF47323 463 584 6.21E-33 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 584 25.798 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 PANTHER PTHR11956 4 584 3.9E-211 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 SMART SM01016 9 89 7.4E-22 T 23-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 125 136 - T 23-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 Gene3D G3DSA:1.10.730.10 463 584 1.1E-34 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS19405 8a6d86d82e59c83992536d2038823d46 584 SUPERFAMILY SSF55190 8 98 2.49E-14 T 23-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Pfam PF01799 [2Fe-2S] binding domain 72 141 1.1E-23 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 SUPERFAMILY SSF54292 3 77 5.51E-20 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Gene3D G3DSA:3.30.365.10 335 443 3.0E-34 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 SUPERFAMILY SSF54665 153 301 3.79E-43 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 SUPERFAMILY SSF56003 285 911 1.44E-171 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Gene3D G3DSA:1.10.150.120 74 146 2.3E-24 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 316 849 1.6E-147 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Gene3D G3DSA:3.30.365.10 447 521 4.1E-38 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Gene3D G3DSA:3.30.365.10 271 334 4.1E-38 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 PANTHER PTHR11908:SF96 156 915 1.7E-291 T 23-04-2016 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Gene3D G3DSA:3.30.365.10 612 759 7.9E-31 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 58 4.8E-5 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Gene3D G3DSA:3.30.365.10 524 611 8.9E-50 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Gene3D G3DSA:3.30.365.10 766 911 8.9E-50 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 170 282 3.0E-28 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Gene3D G3DSA:3.90.1170.50 147 270 4.0E-40 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 SUPERFAMILY SSF47741 84 149 4.32E-22 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 SMART SM01008 170 282 6.5E-51 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 Gene3D G3DSA:3.10.20.30 3 73 6.4E-25 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS07335 9ea769b6be5be3140e7892a0530352ef 932 PANTHER PTHR11908 156 915 1.7E-291 T 23-04-2016 DC74_RS32360 b899fe325fe7f813cd5f031db15dcedd 250 SUPERFAMILY SSF51735 18 200 1.6E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32360 b899fe325fe7f813cd5f031db15dcedd 250 Gene3D G3DSA:3.40.50.720 16 193 1.9E-19 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32360 b899fe325fe7f813cd5f031db15dcedd 250 PANTHER PTHR10366 21 220 3.2E-20 T 23-04-2016 DC74_RS32360 b899fe325fe7f813cd5f031db15dcedd 250 Pfam PF01370 NAD dependent epimerase/dehydratase family 17 177 5.8E-23 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS29325 bca7b25095d9612592e73d05e2f2ba9d 307 PANTHER PTHR30011 4 251 4.3E-88 T 23-04-2016 DC74_RS29325 bca7b25095d9612592e73d05e2f2ba9d 307 PANTHER PTHR30011:SF5 4 251 4.3E-88 T 23-04-2016 DC74_RS29325 bca7b25095d9612592e73d05e2f2ba9d 307 Gene3D G3DSA:3.20.20.30 8 305 7.8E-75 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS29325 bca7b25095d9612592e73d05e2f2ba9d 307 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 2 228 5.3E-91 T 23-04-2016 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c DC74_RS29325 bca7b25095d9612592e73d05e2f2ba9d 307 Pfam PF00296 Luciferase-like monooxygenase 8 248 1.0E-53 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS29325 bca7b25095d9612592e73d05e2f2ba9d 307 SUPERFAMILY SSF51679 4 304 6.67E-66 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS17505 b147dae39fea2094b6eb00c142d75fa1 196 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 118 128 - T 23-04-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 DC74_RS17505 b147dae39fea2094b6eb00c142d75fa1 196 PANTHER PTHR17224 7 196 3.6E-76 T 23-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 DC74_RS17505 b147dae39fea2094b6eb00c142d75fa1 196 Gene3D G3DSA:3.40.50.1470 5 195 9.2E-69 T 23-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 DC74_RS17505 b147dae39fea2094b6eb00c142d75fa1 196 SUPERFAMILY SSF53178 7 195 1.7E-61 T 23-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 DC74_RS17505 b147dae39fea2094b6eb00c142d75fa1 196 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 7 188 32.326 T 23-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 DC74_RS17505 b147dae39fea2094b6eb00c142d75fa1 196 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 20 33 - T 23-04-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 DC74_RS17505 b147dae39fea2094b6eb00c142d75fa1 196 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 9 195 7.7E-51 T 23-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 DC74_RS17505 b147dae39fea2094b6eb00c142d75fa1 196 Pfam PF01195 Peptidyl-tRNA hydrolase 9 193 1.6E-51 T 23-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 DC74_RS30585 f54ed5f861d77dea48dd17695387d3f6 407 SUPERFAMILY SSF56059 82 315 5.48E-42 T 23-04-2016 DC74_RS30585 f54ed5f861d77dea48dd17695387d3f6 407 Gene3D G3DSA:3.40.50.20 73 111 3.9E-8 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS30585 f54ed5f861d77dea48dd17695387d3f6 407 Gene3D G3DSA:3.30.1490.20 112 180 2.8E-17 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS30585 f54ed5f861d77dea48dd17695387d3f6 407 Pfam PF13535 ATP-grasp domain 133 277 1.2E-19 T 23-04-2016 DC74_RS30585 f54ed5f861d77dea48dd17695387d3f6 407 Gene3D G3DSA:3.30.470.20 181 308 3.5E-14 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS30585 f54ed5f861d77dea48dd17695387d3f6 407 PANTHER PTHR23132 91 284 2.7E-18 T 23-04-2016 DC74_RS30585 f54ed5f861d77dea48dd17695387d3f6 407 SMART SM01209 98 273 1.3E-5 T 23-04-2016 DC74_RS07700 dcd35af386f98751e84b9a5dd327d78a 200 SUPERFAMILY SSF52096 5 195 8.59E-58 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS07700 dcd35af386f98751e84b9a5dd327d78a 200 PANTHER PTHR10381:SF7 6 200 9.2E-123 T 23-04-2016 DC74_RS07700 dcd35af386f98751e84b9a5dd327d78a 200 Pfam PF00574 Clp protease 15 195 2.8E-69 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA DC74_RS07700 dcd35af386f98751e84b9a5dd327d78a 200 PRINTS PR00127 Clp protease catalytic subunit P signature 92 109 4.6E-40 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS07700 dcd35af386f98751e84b9a5dd327d78a 200 PRINTS PR00127 Clp protease catalytic subunit P signature 171 190 4.6E-40 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS07700 dcd35af386f98751e84b9a5dd327d78a 200 PRINTS PR00127 Clp protease catalytic subunit P signature 21 36 4.6E-40 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS07700 dcd35af386f98751e84b9a5dd327d78a 200 PRINTS PR00127 Clp protease catalytic subunit P signature 113 132 4.6E-40 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS07700 dcd35af386f98751e84b9a5dd327d78a 200 PRINTS PR00127 Clp protease catalytic subunit P signature 61 81 4.6E-40 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS07700 dcd35af386f98751e84b9a5dd327d78a 200 PANTHER PTHR10381 6 200 9.2E-123 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA DC74_RS07700 dcd35af386f98751e84b9a5dd327d78a 200 Gene3D G3DSA:3.90.226.10 6 195 3.3E-68 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS07700 dcd35af386f98751e84b9a5dd327d78a 200 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 5 196 36.567 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS06300 3add6dc884e6567b5f6ab0208c7f2c87 299 SMART SM00347 26 124 3.4E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS06300 3add6dc884e6567b5f6ab0208c7f2c87 299 Gene3D G3DSA:3.40.630.30 184 293 1.6E-29 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06300 3add6dc884e6567b5f6ab0208c7f2c87 299 Pfam PF12802 MarR family 34 87 4.8E-11 T 23-04-2016 DC74_RS06300 3add6dc884e6567b5f6ab0208c7f2c87 299 SUPERFAMILY SSF55729 151 292 1.89E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06300 3add6dc884e6567b5f6ab0208c7f2c87 299 Gene3D G3DSA:1.10.10.10 6 139 4.3E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06300 3add6dc884e6567b5f6ab0208c7f2c87 299 PANTHER PTHR13947 188 284 5.6E-21 T 23-04-2016 DC74_RS06300 3add6dc884e6567b5f6ab0208c7f2c87 299 Pfam PF00583 Acetyltransferase (GNAT) family 198 274 3.6E-15 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS06300 3add6dc884e6567b5f6ab0208c7f2c87 299 SUPERFAMILY SSF46785 9 138 1.18E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS30130 d5b8764042b8c402d9230afcf7571227 96 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 87 4.8E-17 T 23-04-2016 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 DC74_RS30130 d5b8764042b8c402d9230afcf7571227 96 Pfam PF09827 CRISPR associated protein Cas2 1 75 1.1E-19 T 23-04-2016 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 DC74_RS30130 d5b8764042b8c402d9230afcf7571227 96 SUPERFAMILY SSF143430 1 85 2.88E-21 T 23-04-2016 DC74_RS30130 d5b8764042b8c402d9230afcf7571227 96 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 96 13.94 T 23-04-2016 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 DC74_RS30130 d5b8764042b8c402d9230afcf7571227 96 PANTHER PTHR34405:SF1 1 96 4.0E-20 T 23-04-2016 DC74_RS30130 d5b8764042b8c402d9230afcf7571227 96 PANTHER PTHR34405 1 96 4.0E-20 T 23-04-2016 DC74_RS30130 d5b8764042b8c402d9230afcf7571227 96 PIRSF PIRSF032582 1 96 4.5E-30 T 23-04-2016 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 DC74_RS30130 d5b8764042b8c402d9230afcf7571227 96 Gene3D G3DSA:3.30.70.240 2 71 3.2E-22 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS11240 3179f1f09dbede19d68fc07e3493ea25 137 Gene3D G3DSA:2.40.50.140 77 136 1.2E-22 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS11240 3179f1f09dbede19d68fc07e3493ea25 137 SUPERFAMILY SSF141322 74 136 1.12E-5 T 23-04-2016 DC74_RS11240 3179f1f09dbede19d68fc07e3493ea25 137 Pfam PF01957 NfeD-like C-terminal, partner-binding 3 136 6.7E-17 T 23-04-2016 IPR002810 NfeD-like, C-terminal domain DC74_RS11240 3179f1f09dbede19d68fc07e3493ea25 137 PANTHER PTHR33507 1 136 1.6E-23 T 23-04-2016 DC74_RS24630 6e7981e5304bd3b35836e3888b2c1554 334 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 50 322 7.0E-47 T 23-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 DC74_RS24630 6e7981e5304bd3b35836e3888b2c1554 334 Gene3D G3DSA:3.40.190.10 268 333 6.7E-21 T 23-04-2016 DC74_RS24630 6e7981e5304bd3b35836e3888b2c1554 334 Gene3D G3DSA:3.40.190.10 47 133 6.7E-21 T 23-04-2016 DC74_RS24630 6e7981e5304bd3b35836e3888b2c1554 334 PANTHER PTHR30177 36 326 1.8E-76 T 23-04-2016 DC74_RS24630 6e7981e5304bd3b35836e3888b2c1554 334 PANTHER PTHR30177:SF0 36 326 1.8E-76 T 23-04-2016 DC74_RS24630 6e7981e5304bd3b35836e3888b2c1554 334 Gene3D G3DSA:3.40.190.100 135 267 7.0E-23 T 23-04-2016 DC74_RS24630 6e7981e5304bd3b35836e3888b2c1554 334 SUPERFAMILY SSF53850 44 332 1.05E-54 T 23-04-2016 DC74_RS01040 17fafbcfba26a1d6e6bbbad655252423 195 Gene3D G3DSA:1.10.357.10 6 191 9.0E-30 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS01040 17fafbcfba26a1d6e6bbbad655252423 195 PANTHER PTHR30055 4 175 9.8E-21 T 23-04-2016 DC74_RS01040 17fafbcfba26a1d6e6bbbad655252423 195 SUPERFAMILY SSF48498 108 189 3.07E-5 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS01040 17fafbcfba26a1d6e6bbbad655252423 195 SUPERFAMILY SSF46689 11 81 6.48E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01040 17fafbcfba26a1d6e6bbbad655252423 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 3.4E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS04750 fc233e6061e6e73e5343861e0efcd030 120 PANTHER PTHR37828 14 113 2.5E-17 T 23-04-2016 DC74_RS04750 fc233e6061e6e73e5343861e0efcd030 120 Gene3D G3DSA:3.30.70.1060 16 98 3.3E-11 T 23-04-2016 DC74_RS04750 fc233e6061e6e73e5343861e0efcd030 120 PANTHER PTHR37828:SF1 14 113 2.5E-17 T 23-04-2016 DC74_RS04750 fc233e6061e6e73e5343861e0efcd030 120 Pfam PF03795 YCII-related domain 15 97 7.2E-12 T 23-04-2016 IPR005545 YCII-related DC74_RS04750 fc233e6061e6e73e5343861e0efcd030 120 SUPERFAMILY SSF54909 15 98 4.02E-13 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS06865 ec8d39dc33664cd5c092bfb818a2b2e7 602 Pfam PF00664 ABC transporter transmembrane region 18 288 3.1E-35 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS06865 ec8d39dc33664cd5c092bfb818a2b2e7 602 PANTHER PTHR24221 3 579 5.6E-203 T 23-04-2016 DC74_RS06865 ec8d39dc33664cd5c092bfb818a2b2e7 602 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS06865 ec8d39dc33664cd5c092bfb818a2b2e7 602 SUPERFAMILY SSF90123 6 321 4.19E-63 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS06865 ec8d39dc33664cd5c092bfb818a2b2e7 602 Gene3D G3DSA:1.20.1560.10 6 321 1.5E-54 T 23-04-2016 DC74_RS06865 ec8d39dc33664cd5c092bfb818a2b2e7 602 SMART SM00382 360 561 1.8E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS06865 ec8d39dc33664cd5c092bfb818a2b2e7 602 Gene3D G3DSA:3.40.50.300 335 575 1.3E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06865 ec8d39dc33664cd5c092bfb818a2b2e7 602 Pfam PF00005 ABC transporter 351 499 1.3E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS06865 ec8d39dc33664cd5c092bfb818a2b2e7 602 SUPERFAMILY SSF52540 325 570 4.13E-80 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06865 ec8d39dc33664cd5c092bfb818a2b2e7 602 PANTHER PTHR24221:SF190 3 579 5.6E-203 T 23-04-2016 DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 Pfam PF05593 RHS Repeat 461 489 1.2E-5 T 23-04-2016 IPR031325 RHS repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 Pfam PF05593 RHS Repeat 410 445 9.7E-9 T 23-04-2016 IPR031325 RHS repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 Pfam PF05593 RHS Repeat 320 355 7.1E-7 T 23-04-2016 IPR031325 RHS repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 Pfam PF05593 RHS Repeat 663 691 2.6E-5 T 23-04-2016 IPR031325 RHS repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 Pfam PF05593 RHS Repeat 516 547 8.1E-7 T 23-04-2016 IPR031325 RHS repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 Pfam PF05593 RHS Repeat 937 966 3.7E-7 T 23-04-2016 IPR031325 RHS repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 Pfam PF05593 RHS Repeat 683 713 5.0E-5 T 23-04-2016 IPR031325 RHS repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 Pfam PF05593 RHS Repeat 393 425 6.9E-7 T 23-04-2016 IPR031325 RHS repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 Pfam PF05593 RHS Repeat 620 656 2.8E-6 T 23-04-2016 IPR031325 RHS repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 Pfam PF05593 RHS Repeat 641 678 4.0E-8 T 23-04-2016 IPR031325 RHS repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 Pfam PF05593 RHS Repeat 578 614 2.4E-6 T 23-04-2016 IPR031325 RHS repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 Pfam PF05593 RHS Repeat 473 508 1.5E-9 T 23-04-2016 IPR031325 RHS repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 PANTHER PTHR32305 862 1143 3.1E-118 T 23-04-2016 DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 PANTHER PTHR32305 233 789 3.1E-118 T 23-04-2016 DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1069 1143 7.6E-22 T 23-04-2016 IPR022385 Rhs repeat-associated core GO:0097264 DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 PANTHER PTHR32305:SF6 862 1143 3.1E-118 T 23-04-2016 DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 PANTHER PTHR32305:SF6 233 789 3.1E-118 T 23-04-2016 DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 724 763 6.9E-5 T 23-04-2016 IPR006530 YD repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 515 556 3.2E-9 T 23-04-2016 IPR006530 YD repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 480 513 2.5E-8 T 23-04-2016 IPR006530 YD repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 560 597 1.0E-7 T 23-04-2016 IPR006530 YD repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 620 660 9.6E-11 T 23-04-2016 IPR006530 YD repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 375 408 8.5E-5 T 23-04-2016 IPR006530 YD repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 320 354 3.9E-5 T 23-04-2016 IPR006530 YD repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 744 779 6.1E-4 T 23-04-2016 IPR006530 YD repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 663 694 7.0E-6 T 23-04-2016 IPR006530 YD repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 852 887 1.3E-5 T 23-04-2016 IPR006530 YD repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 410 446 8.5E-8 T 23-04-2016 IPR006530 YD repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 937 969 2.0E-8 T 23-04-2016 IPR006530 YD repeat DC74_RS09360 42bbbdeb0c7eb355e8af37196c03363a 1276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 457 485 0.0027 T 23-04-2016 IPR006530 YD repeat DC74_RS03040 65c44d2687e63a8b5e9cc51c1c4dd785 367 PANTHER PTHR11695 130 366 3.6E-124 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS03040 65c44d2687e63a8b5e9cc51c1c4dd785 367 PANTHER PTHR11695 15 107 3.6E-124 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS03040 65c44d2687e63a8b5e9cc51c1c4dd785 367 SUPERFAMILY SSF50129 1 196 1.02E-50 T 23-04-2016 IPR011032 GroES-like DC74_RS03040 65c44d2687e63a8b5e9cc51c1c4dd785 367 SUPERFAMILY SSF51735 164 331 1.64E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03040 65c44d2687e63a8b5e9cc51c1c4dd785 367 SMART SM00829 13 364 2.1E-4 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS03040 65c44d2687e63a8b5e9cc51c1c4dd785 367 Gene3D G3DSA:3.40.50.720 193 310 5.0E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03040 65c44d2687e63a8b5e9cc51c1c4dd785 367 Gene3D G3DSA:3.90.180.10 2 192 1.8E-50 T 23-04-2016 IPR011032 GroES-like DC74_RS03040 65c44d2687e63a8b5e9cc51c1c4dd785 367 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS03040 65c44d2687e63a8b5e9cc51c1c4dd785 367 PANTHER PTHR11695:SF571 130 366 3.6E-124 T 23-04-2016 DC74_RS03040 65c44d2687e63a8b5e9cc51c1c4dd785 367 PANTHER PTHR11695:SF571 15 107 3.6E-124 T 23-04-2016 DC74_RS03040 65c44d2687e63a8b5e9cc51c1c4dd785 367 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 156 7.4E-23 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS03040 65c44d2687e63a8b5e9cc51c1c4dd785 367 Pfam PF00107 Zinc-binding dehydrogenase 201 324 1.2E-23 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS20215 93c151bbd192779a65e744b35d4cd855 313 Gene3D G3DSA:3.40.190.10 261 312 3.3E-37 T 23-04-2016 DC74_RS20215 93c151bbd192779a65e744b35d4cd855 313 Gene3D G3DSA:3.40.190.10 35 150 3.3E-37 T 23-04-2016 DC74_RS20215 93c151bbd192779a65e744b35d4cd855 313 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 38 305 1.1E-47 T 23-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 DC74_RS20215 93c151bbd192779a65e744b35d4cd855 313 PANTHER PTHR30177 41 311 1.5E-33 T 23-04-2016 DC74_RS20215 93c151bbd192779a65e744b35d4cd855 313 SUPERFAMILY SSF53850 38 311 1.47E-39 T 23-04-2016 DC74_RS20215 93c151bbd192779a65e744b35d4cd855 313 Gene3D G3DSA:3.40.190.120 151 248 1.5E-23 T 23-04-2016 DC74_RS31020 270cab28769f268e4bb6cdb226b72ed8 211 Gene3D G3DSA:1.10.260.40 50 106 1.2E-4 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 SUPERFAMILY SSF56003 137 789 4.71E-180 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 SUPERFAMILY SSF54665 11 164 2.22E-40 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 PANTHER PTHR11908:SF76 607 794 1.1E-245 T 23-04-2016 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 PANTHER PTHR11908:SF76 10 589 1.1E-245 T 23-04-2016 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 Gene3D G3DSA:3.30.365.10 298 375 2.4E-31 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 Gene3D G3DSA:3.30.365.10 132 190 2.4E-31 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 PANTHER PTHR11908 607 794 1.1E-245 T 23-04-2016 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 PANTHER PTHR11908 10 589 1.1E-245 T 23-04-2016 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 Gene3D G3DSA:3.30.365.10 379 467 9.7E-59 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 Gene3D G3DSA:3.30.365.10 640 791 9.7E-59 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 176 725 1.8E-158 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 SMART SM01008 30 144 1.4E-38 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 30 143 4.5E-24 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 Gene3D G3DSA:3.30.365.10 191 294 1.6E-32 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 Gene3D G3DSA:3.30.365.10 468 636 1.2E-45 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS07060 9bb7b2ace7a38ea53f5fb560f699a128 797 Gene3D G3DSA:3.90.1170.50 10 131 3.1E-38 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS00150 562051ea17768cb914fb3cdc85f8486b 207 Pfam PF14124 Domain of unknown function (DUF4291) 16 193 2.2E-70 T 23-04-2016 IPR025633 Protein of unknown function DUF4291 DC74_RS00150 562051ea17768cb914fb3cdc85f8486b 207 PANTHER PTHR38567 13 204 2.7E-75 T 23-04-2016 DC74_RS38040 3b90cee39fd6fd2bc213ca6ec4549656 291 PANTHER PTHR32243 145 284 8.3E-66 T 23-04-2016 DC74_RS38040 3b90cee39fd6fd2bc213ca6ec4549656 291 PANTHER PTHR32243:SF40 1 129 8.3E-66 T 23-04-2016 DC74_RS38040 3b90cee39fd6fd2bc213ca6ec4549656 291 SUPERFAMILY SSF161098 48 275 1.07E-48 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38040 3b90cee39fd6fd2bc213ca6ec4549656 291 PANTHER PTHR32243:SF40 145 284 8.3E-66 T 23-04-2016 DC74_RS38040 3b90cee39fd6fd2bc213ca6ec4549656 291 PANTHER PTHR32243 1 129 8.3E-66 T 23-04-2016 DC74_RS38040 3b90cee39fd6fd2bc213ca6ec4549656 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 279 5.7E-13 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38040 3b90cee39fd6fd2bc213ca6ec4549656 291 Gene3D G3DSA:1.10.3720.10 2 279 8.0E-51 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38135 ecd1e5d69997057ce49ae7a57c33f428 115 Gene3D G3DSA:2.60.40.920 21 105 1.4E-4 T 23-04-2016 IPR003344 Big-1 (bacterial Ig-like domain 1) domain DC74_RS38135 ecd1e5d69997057ce49ae7a57c33f428 115 SUPERFAMILY SSF49373 21 105 1.06E-6 T 23-04-2016 IPR008964 Invasin/intimin cell-adhesion fragments DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 Pfam PF00512 His Kinase A (phospho-acceptor) domain 619 686 2.2E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 SUPERFAMILY SSF55874 676 834 3.8E-36 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 SMART SM00388 618 686 9.0E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 PANTHER PTHR24423 3 178 3.8E-123 T 23-04-2016 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 PANTHER PTHR24423 591 833 3.8E-123 T 23-04-2016 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 PANTHER PTHR24423 481 520 3.8E-123 T 23-04-2016 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 PANTHER PTHR24423:SF562 3 178 3.8E-123 T 23-04-2016 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 PANTHER PTHR24423:SF562 591 833 3.8E-123 T 23-04-2016 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 PANTHER PTHR24423:SF562 481 520 3.8E-123 T 23-04-2016 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 Pfam PF00582 Universal stress protein family 232 346 1.5E-5 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 211 1.0E-100 T 23-04-2016 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 Gene3D G3DSA:1.10.287.130 609 672 1.2E-18 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 Gene3D G3DSA:3.40.50.620 226 346 1.3E-11 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 781 791 1.9E-12 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 820 833 1.9E-12 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 796 814 1.9E-12 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 PRINTS PR00344 Bacterial sensor protein C-terminal signature 763 777 1.9E-12 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 Pfam PF13493 Domain of unknown function (DUF4118) 383 488 1.8E-24 T 23-04-2016 IPR025201 Sensor protein KdpD, transmembrane domain DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 Gene3D G3DSA:3.40.50.300 2 210 5.0E-100 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 Gene3D G3DSA:1.20.120.620 380 480 2.0E-18 T 23-04-2016 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 Gene3D G3DSA:3.30.565.10 673 834 5.5E-38 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 727 834 1.2E-17 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 SUPERFAMILY SSF52402 231 348 3.14E-9 T 23-04-2016 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 SUPERFAMILY SSF47384 608 686 1.77E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS29210 22980d084388eaefc8ce86f9b78b46b0 851 SMART SM00387 726 836 1.6E-26 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 SUPERFAMILY SSF52540 158 470 5.08E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 374 469 9.8E-22 T 23-04-2016 IPR025158 Mg chelatase-related protein, C-terminal domain DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 Gene3D G3DSA:3.30.230.10 4 116 6.7E-25 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 PANTHER PTHR32039 1 131 6.5E-174 T 23-04-2016 DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 Pfam PF01078 Magnesium chelatase, subunit ChlI 158 364 1.5E-83 T 23-04-2016 IPR000523 Magnesium chelatase ChlI domain DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 SUPERFAMILY SSF54211 3 117 3.53E-24 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 PANTHER PTHR32039:SF7 1 131 6.5E-174 T 23-04-2016 IPR004482 Mg chelatase-related protein DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 Pfam PF13541 Subunit ChlI of Mg-chelatase 2 88 3.5E-25 T 23-04-2016 DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 2 469 1.3E-116 T 23-04-2016 IPR004482 Mg chelatase-related protein DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 Gene3D G3DSA:3.40.50.300 157 357 2.3E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 PANTHER PTHR32039:SF7 158 499 6.5E-174 T 23-04-2016 IPR004482 Mg chelatase-related protein DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 PANTHER PTHR32039 158 499 6.5E-174 T 23-04-2016 DC74_RS28170 55ff50aed24bd90424fb4e62e71fb789 575 SMART SM00382 178 362 1.8E-5 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 Gene3D G3DSA:3.40.50.720 9 258 9.4E-84 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 SUPERFAMILY SSF51735 13 258 1.19E-77 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 258 2.4E-69 T 23-04-2016 DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PANTHER PTHR24322:SF330 165 197 1.7E-60 T 23-04-2016 DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PANTHER PTHR24322 165 197 1.7E-60 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 2.7E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.7E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.7E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 2.7E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 2.7E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 2.7E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PANTHER PTHR24322:SF330 18 148 1.7E-60 T 23-04-2016 DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.4E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 1.4E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 1.4E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10145 d7355a7f4b3f72a13b1e1aa6d11fa443 266 PANTHER PTHR24322 18 148 1.7E-60 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS23285 104646936e34e647458da08c75a95cb7 253 Gene3D G3DSA:3.40.50.1240 5 253 3.2E-87 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS23285 104646936e34e647458da08c75a95cb7 253 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 23-04-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 DC74_RS23285 104646936e34e647458da08c75a95cb7 253 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 133 1.2E-25 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS23285 104646936e34e647458da08c75a95cb7 253 PANTHER PTHR11931 4 253 2.2E-151 T 23-04-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 DC74_RS23285 104646936e34e647458da08c75a95cb7 253 SMART SM00855 7 193 7.4E-22 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS23285 104646936e34e647458da08c75a95cb7 253 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 7 251 5.2E-111 T 23-04-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 DC74_RS23285 104646936e34e647458da08c75a95cb7 253 SUPERFAMILY SSF53254 6 225 1.63E-68 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS23285 104646936e34e647458da08c75a95cb7 253 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 5 234 41.964 T 23-04-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 DC74_RS33215 f56f2d7505498ddc4e5e7990f3e43bc7 314 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 172 197 - T 23-04-2016 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 DC74_RS33215 f56f2d7505498ddc4e5e7990f3e43bc7 314 Pfam PF00494 Squalene/phytoene synthase 24 285 9.7E-70 T 23-04-2016 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 DC74_RS33215 f56f2d7505498ddc4e5e7990f3e43bc7 314 PANTHER PTHR31480:SF5 11 312 4.5E-129 T 23-04-2016 DC74_RS33215 f56f2d7505498ddc4e5e7990f3e43bc7 314 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 22 294 1.4E-92 T 23-04-2016 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 DC74_RS33215 f56f2d7505498ddc4e5e7990f3e43bc7 314 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 137 152 - T 23-04-2016 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 DC74_RS33215 f56f2d7505498ddc4e5e7990f3e43bc7 314 PANTHER PTHR31480 11 312 4.5E-129 T 23-04-2016 DC74_RS33215 f56f2d7505498ddc4e5e7990f3e43bc7 314 Gene3D G3DSA:1.10.600.10 11 302 1.8E-80 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS33215 f56f2d7505498ddc4e5e7990f3e43bc7 314 SUPERFAMILY SSF48576 14 298 2.01E-72 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 SUPERFAMILY SSF52540 4 166 2.0E-25 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 PANTHER PTHR21087 6 167 5.5E-45 T 23-04-2016 DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 Hamap MF_00109 Shikimate kinase [aroK]. 3 167 25.54 T 23-04-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 ProSitePatterns PS01128 Shikimate kinase signature. 59 84 - T 23-04-2016 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 PANTHER PTHR21087:SF0 6 167 5.5E-45 T 23-04-2016 DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 Gene3D G3DSA:3.40.50.300 5 167 6.8E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 Pfam PF01202 Shikimate kinase 12 166 2.4E-40 T 23-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 SMART SM00382 2 182 8.7E-4 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 PRINTS PR01100 Shikimate kinase family signature 58 66 2.4E-14 T 23-04-2016 DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 PRINTS PR01100 Shikimate kinase family signature 76 85 2.4E-14 T 23-04-2016 DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 PRINTS PR01100 Shikimate kinase family signature 96 113 2.4E-14 T 23-04-2016 DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 PRINTS PR01100 Shikimate kinase family signature 6 21 2.4E-14 T 23-04-2016 DC74_RS09500 110376abbfc0e8fe737911c015ce9906 184 PRINTS PR01100 Shikimate kinase family signature 30 43 2.4E-14 T 23-04-2016 DC74_RS11580 4fefe65add0b608bc447629df04a2b89 422 Gene3D G3DSA:3.90.1150.10 21 61 6.4E-30 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS11580 4fefe65add0b608bc447629df04a2b89 422 Gene3D G3DSA:3.90.1150.10 324 419 6.4E-30 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS11580 4fefe65add0b608bc447629df04a2b89 422 PANTHER PTHR11986:SF61 3 420 3.6E-245 T 23-04-2016 DC74_RS11580 4fefe65add0b608bc447629df04a2b89 422 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 6 420 1.9E-142 T 23-04-2016 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|UniPathway: UPA00067 DC74_RS11580 4fefe65add0b608bc447629df04a2b89 422 SUPERFAMILY SSF53383 12 419 2.53E-107 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS11580 4fefe65add0b608bc447629df04a2b89 422 Pfam PF00202 Aminotransferase class-III 27 417 2.2E-75 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS11580 4fefe65add0b608bc447629df04a2b89 422 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 10 419 1.5E-203 T 23-04-2016 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|UniPathway: UPA00067 DC74_RS11580 4fefe65add0b608bc447629df04a2b89 422 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS11580 4fefe65add0b608bc447629df04a2b89 422 Gene3D G3DSA:3.40.640.10 62 318 5.2E-61 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS11580 4fefe65add0b608bc447629df04a2b89 422 PANTHER PTHR11986 3 420 3.6E-245 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS39685 2f3ecbaaf30862606a0c7c7370472b41 195 SUPERFAMILY SSF49777 26 169 8.24E-28 T 23-04-2016 IPR008914 Phosphatidylethanolamine-binding protein DC74_RS39685 2f3ecbaaf30862606a0c7c7370472b41 195 Pfam PF01161 Phosphatidylethanolamine-binding protein 44 190 5.1E-19 T 23-04-2016 IPR008914 Phosphatidylethanolamine-binding protein DC74_RS39685 2f3ecbaaf30862606a0c7c7370472b41 195 Gene3D G3DSA:3.90.280.10 30 192 4.0E-30 T 23-04-2016 IPR008914 Phosphatidylethanolamine-binding protein DC74_RS39685 2f3ecbaaf30862606a0c7c7370472b41 195 PANTHER PTHR30289 26 163 1.0E-19 T 23-04-2016 DC74_RS39530 f5cede304e09d822841989f508adc3f0 497 SUPERFAMILY SSF75005 52 342 6.16E-54 T 23-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain DC74_RS39530 f5cede304e09d822841989f508adc3f0 497 PANTHER PTHR22925:SF12 57 365 8.7E-111 T 23-04-2016 DC74_RS39530 f5cede304e09d822841989f508adc3f0 497 PANTHER PTHR22925 57 365 8.7E-111 T 23-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 DC74_RS39530 f5cede304e09d822841989f508adc3f0 497 Pfam PF04616 Glycosyl hydrolases family 43 58 341 3.4E-61 T 23-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 DC74_RS39530 f5cede304e09d822841989f508adc3f0 497 Gene3D G3DSA:2.115.10.20 53 356 9.5E-75 T 23-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain DC74_RS21855 be42aa1daa58c2719c4d25ca1603ef2d 499 Gene3D G3DSA:1.20.1250.20 39 218 1.6E-16 T 23-04-2016 DC74_RS21855 be42aa1daa58c2719c4d25ca1603ef2d 499 Pfam PF07690 Major Facilitator Superfamily 45 441 1.7E-28 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS21855 be42aa1daa58c2719c4d25ca1603ef2d 499 SUPERFAMILY SSF103473 38 227 9.55E-46 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21855 be42aa1daa58c2719c4d25ca1603ef2d 499 SUPERFAMILY SSF103473 275 489 9.55E-46 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21855 be42aa1daa58c2719c4d25ca1603ef2d 499 PANTHER PTHR23501 37 486 1.6E-72 T 23-04-2016 DC74_RS21855 be42aa1daa58c2719c4d25ca1603ef2d 499 Gene3D G3DSA:1.20.1250.20 284 489 4.7E-17 T 23-04-2016 DC74_RS29000 9715303c4438cfdd58c93303aa322561 330 PANTHER PTHR11751 181 199 2.8E-21 T 23-04-2016 DC74_RS29000 9715303c4438cfdd58c93303aa322561 330 PANTHER PTHR11751:SF436 181 199 2.8E-21 T 23-04-2016 DC74_RS29000 9715303c4438cfdd58c93303aa322561 330 SMART SM00895 183 307 9.9E-22 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS29000 9715303c4438cfdd58c93303aa322561 330 Pfam PF00392 Bacterial regulatory proteins, gntR family 95 154 2.7E-14 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS29000 9715303c4438cfdd58c93303aa322561 330 SMART SM00345 96 154 1.1E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS29000 9715303c4438cfdd58c93303aa322561 330 Gene3D G3DSA:1.10.10.10 87 156 1.6E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29000 9715303c4438cfdd58c93303aa322561 330 SUPERFAMILY SSF48008 180 307 4.18E-26 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS29000 9715303c4438cfdd58c93303aa322561 330 Gene3D G3DSA:1.20.120.530 180 307 5.5E-25 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS29000 9715303c4438cfdd58c93303aa322561 330 PANTHER PTHR11751 95 161 2.8E-21 T 23-04-2016 DC74_RS29000 9715303c4438cfdd58c93303aa322561 330 PANTHER PTHR11751:SF436 95 161 2.8E-21 T 23-04-2016 DC74_RS29000 9715303c4438cfdd58c93303aa322561 330 Pfam PF07729 FCD domain 183 306 4.4E-22 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS29000 9715303c4438cfdd58c93303aa322561 330 SUPERFAMILY SSF46785 88 158 2.77E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04935 a80b6b0ea10f528fa29176cdf8a70c1b 191 PANTHER PTHR30295:SF4 32 191 4.5E-68 T 23-04-2016 DC74_RS04935 a80b6b0ea10f528fa29176cdf8a70c1b 191 ProSitePatterns PS00819 Dps protein family signature 2. 90 104 - T 23-04-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 DC74_RS04935 a80b6b0ea10f528fa29176cdf8a70c1b 191 SUPERFAMILY SSF47240 23 183 2.71E-36 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS04935 a80b6b0ea10f528fa29176cdf8a70c1b 191 ProSitePatterns PS00818 Dps protein family signature 1. 64 80 - T 23-04-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 DC74_RS04935 a80b6b0ea10f528fa29176cdf8a70c1b 191 PIRSF PIRSF005900 21 189 2.7E-43 T 23-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 DC74_RS04935 a80b6b0ea10f528fa29176cdf8a70c1b 191 PANTHER PTHR30295 32 191 4.5E-68 T 23-04-2016 DC74_RS04935 a80b6b0ea10f528fa29176cdf8a70c1b 191 Gene3D G3DSA:1.20.1260.10 16 189 4.7E-50 T 23-04-2016 IPR012347 Ferritin-related DC74_RS04935 a80b6b0ea10f528fa29176cdf8a70c1b 191 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 88 104 8.5E-6 T 23-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 DC74_RS04935 a80b6b0ea10f528fa29176cdf8a70c1b 191 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 64 80 8.5E-6 T 23-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 DC74_RS04935 a80b6b0ea10f528fa29176cdf8a70c1b 191 Pfam PF00210 Ferritin-like domain 45 187 6.5E-28 T 23-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 DC74_RS20310 ce7cf39663699d2b024c6a7d2b7b9705 604 SUPERFAMILY SSF52833 20 158 1.64E-31 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS20310 ce7cf39663699d2b024c6a7d2b7b9705 604 Gene3D G3DSA:3.40.30.10 9 152 7.8E-41 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS20310 ce7cf39663699d2b024c6a7d2b7b9705 604 PANTHER PTHR13833:SF38 5 437 2.5E-120 T 23-04-2016 DC74_RS20310 ce7cf39663699d2b024c6a7d2b7b9705 604 Gene3D G3DSA:2.120.10.30 173 471 2.3E-46 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS20310 ce7cf39663699d2b024c6a7d2b7b9705 604 Pfam PF01436 NHL repeat 399 426 3.8E-5 T 23-04-2016 IPR001258 NHL repeat GO:0005515 DC74_RS20310 ce7cf39663699d2b024c6a7d2b7b9705 604 Pfam PF01436 NHL repeat 224 251 6.3E-7 T 23-04-2016 IPR001258 NHL repeat GO:0005515 DC74_RS20310 ce7cf39663699d2b024c6a7d2b7b9705 604 PANTHER PTHR13833 5 437 2.5E-120 T 23-04-2016 DC74_RS20310 ce7cf39663699d2b024c6a7d2b7b9705 604 Pfam PF00578 AhpC/TSA family 8 129 8.2E-12 T 23-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS20310 ce7cf39663699d2b024c6a7d2b7b9705 604 SUPERFAMILY SSF101898 163 469 4.18E-36 T 23-04-2016 DC74_RS02640 ef1984a5aa7cd255eee894256d797f82 375 PANTHER PTHR22893 1 307 2.3E-209 T 23-04-2016 DC74_RS02640 ef1984a5aa7cd255eee894256d797f82 375 PANTHER PTHR22893:SF9 324 371 2.3E-209 T 23-04-2016 DC74_RS02640 ef1984a5aa7cd255eee894256d797f82 375 SUPERFAMILY SSF51395 10 361 1.75E-94 T 23-04-2016 DC74_RS02640 ef1984a5aa7cd255eee894256d797f82 375 PANTHER PTHR22893:SF9 1 307 2.3E-209 T 23-04-2016 DC74_RS02640 ef1984a5aa7cd255eee894256d797f82 375 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 17 360 1.8E-57 T 23-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 DC74_RS02640 ef1984a5aa7cd255eee894256d797f82 375 Gene3D G3DSA:3.20.20.70 9 362 2.6E-100 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS02640 ef1984a5aa7cd255eee894256d797f82 375 PANTHER PTHR22893 324 371 2.3E-209 T 23-04-2016 DC74_RS10875 4686da4d4606a32649623fae21a7492f 455 PANTHER PTHR30011:SF18 49 451 1.5E-125 T 23-04-2016 DC74_RS10875 4686da4d4606a32649623fae21a7492f 455 Pfam PF00296 Luciferase-like monooxygenase 46 396 1.2E-55 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10875 4686da4d4606a32649623fae21a7492f 455 SUPERFAMILY SSF51679 39 448 1.05E-100 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10875 4686da4d4606a32649623fae21a7492f 455 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 44 442 8.8E-118 T 23-04-2016 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 DC74_RS10875 4686da4d4606a32649623fae21a7492f 455 PANTHER PTHR30011 49 451 1.5E-125 T 23-04-2016 DC74_RS10875 4686da4d4606a32649623fae21a7492f 455 Gene3D G3DSA:3.20.20.30 363 449 4.8E-108 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10875 4686da4d4606a32649623fae21a7492f 455 Gene3D G3DSA:3.20.20.30 7 313 4.8E-108 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10875 4686da4d4606a32649623fae21a7492f 455 PIRSF PIRSF000337 25 455 2.2E-135 T 23-04-2016 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 DC74_RS39060 7611fe28b8285c872db7dd37da86790e 286 Pfam PF13649 Methyltransferase domain 55 156 2.1E-18 T 23-04-2016 DC74_RS39060 7611fe28b8285c872db7dd37da86790e 286 PANTHER PTHR10108 272 281 9.1E-31 T 23-04-2016 DC74_RS39060 7611fe28b8285c872db7dd37da86790e 286 PANTHER PTHR10108 19 230 9.1E-31 T 23-04-2016 DC74_RS39060 7611fe28b8285c872db7dd37da86790e 286 Gene3D G3DSA:3.40.50.150 41 271 4.8E-41 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS39060 7611fe28b8285c872db7dd37da86790e 286 SUPERFAMILY SSF53335 11 239 1.15E-41 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS08100 5b1f83b0276b6f606148a954f38c6159 249 Pfam PF00376 MerR family regulatory protein 33 64 9.9E-11 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS08100 5b1f83b0276b6f606148a954f38c6159 249 PANTHER PTHR30204:SF9 14 100 1.3E-38 T 23-04-2016 DC74_RS08100 5b1f83b0276b6f606148a954f38c6159 249 SMART SM00422 22 96 1.7E-16 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS08100 5b1f83b0276b6f606148a954f38c6159 249 PANTHER PTHR30204 14 100 1.3E-38 T 23-04-2016 DC74_RS08100 5b1f83b0276b6f606148a954f38c6159 249 Gene3D G3DSA:1.10.1660.10 37 101 5.4E-17 T 23-04-2016 DC74_RS08100 5b1f83b0276b6f606148a954f38c6159 249 SUPERFAMILY SSF46955 37 100 5.04E-12 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS37450 b8da2eb712e58e12e3a39efab94f6990 354 PANTHER PTHR11695 11 353 1.7E-65 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS37450 b8da2eb712e58e12e3a39efab94f6990 354 Gene3D G3DSA:3.40.50.720 171 279 1.2E-26 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37450 b8da2eb712e58e12e3a39efab94f6990 354 SUPERFAMILY SSF50129 10 176 6.24E-33 T 23-04-2016 IPR011032 GroES-like DC74_RS37450 b8da2eb712e58e12e3a39efab94f6990 354 Pfam PF00107 Zinc-binding dehydrogenase 178 273 1.1E-14 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS37450 b8da2eb712e58e12e3a39efab94f6990 354 SMART SM00829 9 346 5.7E-4 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS37450 b8da2eb712e58e12e3a39efab94f6990 354 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 73 87 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS37450 b8da2eb712e58e12e3a39efab94f6990 354 PANTHER PTHR11695:SF285 11 353 1.7E-65 T 23-04-2016 DC74_RS37450 b8da2eb712e58e12e3a39efab94f6990 354 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 104 6.9E-15 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS37450 b8da2eb712e58e12e3a39efab94f6990 354 Gene3D G3DSA:3.90.180.10 10 170 1.0E-30 T 23-04-2016 IPR011032 GroES-like DC74_RS37450 b8da2eb712e58e12e3a39efab94f6990 354 SUPERFAMILY SSF51735 140 314 3.52E-26 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16505 502de6aa1a1ac66ae24573f743974f8c 215 SUPERFAMILY SSF161098 14 198 1.09E-29 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16505 502de6aa1a1ac66ae24573f743974f8c 215 Gene3D G3DSA:1.10.3720.10 10 187 3.0E-21 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16505 502de6aa1a1ac66ae24573f743974f8c 215 PANTHER PTHR30177:SF13 3 214 3.1E-145 T 23-04-2016 DC74_RS16505 502de6aa1a1ac66ae24573f743974f8c 215 PANTHER PTHR30177 3 214 3.1E-145 T 23-04-2016 DC74_RS16505 502de6aa1a1ac66ae24573f743974f8c 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 206 6.4E-17 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS04505 c6571ff264fd154003ae51c6bfd169ff 232 Gene3D G3DSA:3.30.460.10 11 113 1.2E-8 T 23-04-2016 DC74_RS04505 c6571ff264fd154003ae51c6bfd169ff 232 SUPERFAMILY SSF81301 9 106 8.0E-9 T 23-04-2016 DC74_RS04505 c6571ff264fd154003ae51c6bfd169ff 232 Pfam PF01909 Nucleotidyltransferase domain 8 78 2.9E-5 T 23-04-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 SUPERFAMILY SSF51971 303 444 2.06E-6 T 23-04-2016 DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 PIRSF PIRSF000362 1 448 1.9E-143 T 23-04-2016 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 Gene3D G3DSA:3.40.50.720 1 90 7.7E-63 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 Gene3D G3DSA:3.40.50.720 319 444 7.7E-63 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 Gene3D G3DSA:3.50.50.60 91 318 1.5E-65 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 PANTHER PTHR11938 1 447 5.5E-129 T 23-04-2016 DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 PANTHER PTHR11938:SF4 1 447 5.5E-129 T 23-04-2016 DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 SUPERFAMILY SSF51971 261 319 5.06E-47 T 23-04-2016 DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 SUPERFAMILY SSF51971 1 207 5.06E-47 T 23-04-2016 DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 159 7.2E-8 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 PRINTS PR00419 Adrenodoxin reductase family signature 208 221 4.0E-6 T 23-04-2016 DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 4.0E-6 T 23-04-2016 DC74_RS34365 fd4e8707f341655d93919fb94a12aefe 452 PRINTS PR00419 Adrenodoxin reductase family signature 141 155 4.0E-6 T 23-04-2016 DC74_RS37010 e71d2478bcbf3894f230741040f25462 167 Pfam PF00583 Acetyltransferase (GNAT) family 68 145 1.6E-7 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS37010 e71d2478bcbf3894f230741040f25462 167 Gene3D G3DSA:3.40.630.30 1 164 4.7E-21 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS37010 e71d2478bcbf3894f230741040f25462 167 SUPERFAMILY SSF55729 1 164 6.73E-20 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS07140 a8276511bdc55cadbf2712f890cbccb2 152 Pfam PF00027 Cyclic nucleotide-binding domain 26 112 4.6E-7 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS07140 a8276511bdc55cadbf2712f890cbccb2 152 SUPERFAMILY SSF51206 7 129 9.95E-20 T 23-04-2016 IPR018490 Cyclic nucleotide-binding-like DC74_RS07140 a8276511bdc55cadbf2712f890cbccb2 152 SMART SM00100 7 128 5.4E-5 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS07140 a8276511bdc55cadbf2712f890cbccb2 152 Gene3D G3DSA:2.60.120.10 7 139 6.0E-14 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS06940 d30b7d128b288e172e74e3dd1b060910 398 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 32 394 2.9E-102 T 23-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 DC74_RS06940 d30b7d128b288e172e74e3dd1b060910 398 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 352 376 - T 23-04-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 DC74_RS06940 d30b7d128b288e172e74e3dd1b060910 398 Pfam PF01098 Cell cycle protein 33 393 4.1E-93 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 DC74_RS06940 d30b7d128b288e172e74e3dd1b060910 398 PANTHER PTHR30474 11 394 6.7E-137 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 DC74_RS06940 d30b7d128b288e172e74e3dd1b060910 398 PANTHER PTHR30474:SF1 11 394 6.7E-137 T 23-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 DC74_RS09120 4ccb8852b152bbad686df58008409109 420 Pfam PF13535 ATP-grasp domain 144 300 1.0E-24 T 23-04-2016 DC74_RS09120 4ccb8852b152bbad686df58008409109 420 PANTHER PTHR23132 94 386 1.2E-20 T 23-04-2016 DC74_RS09120 4ccb8852b152bbad686df58008409109 420 SUPERFAMILY SSF56059 91 333 7.95E-40 T 23-04-2016 DC74_RS09120 4ccb8852b152bbad686df58008409109 420 Gene3D G3DSA:3.30.470.20 102 408 2.9E-35 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS16215 b8e5e8c9322d2e0c08e5fad62b1e28d4 373 PANTHER PTHR22604 312 371 5.6E-105 T 23-04-2016 DC74_RS16215 b8e5e8c9322d2e0c08e5fad62b1e28d4 373 PANTHER PTHR22604 5 290 5.6E-105 T 23-04-2016 DC74_RS16215 b8e5e8c9322d2e0c08e5fad62b1e28d4 373 Gene3D G3DSA:3.40.50.720 10 142 4.7E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16215 b8e5e8c9322d2e0c08e5fad62b1e28d4 373 PANTHER PTHR22604:SF53 312 371 5.6E-105 T 23-04-2016 DC74_RS16215 b8e5e8c9322d2e0c08e5fad62b1e28d4 373 PANTHER PTHR22604:SF53 5 290 5.6E-105 T 23-04-2016 DC74_RS16215 b8e5e8c9322d2e0c08e5fad62b1e28d4 373 Gene3D G3DSA:3.30.360.10 143 369 7.5E-38 T 23-04-2016 DC74_RS16215 b8e5e8c9322d2e0c08e5fad62b1e28d4 373 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 146 227 1.2E-11 T 23-04-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 DC74_RS16215 b8e5e8c9322d2e0c08e5fad62b1e28d4 373 SUPERFAMILY SSF55347 141 285 3.6E-28 T 23-04-2016 DC74_RS16215 b8e5e8c9322d2e0c08e5fad62b1e28d4 373 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 12 132 3.5E-22 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 DC74_RS16215 b8e5e8c9322d2e0c08e5fad62b1e28d4 373 SUPERFAMILY SSF51735 10 169 1.16E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00420 17cf4bee57f5725b4eb20910caf6c04e 641 Gene3D G3DSA:3.60.15.10 218 336 6.2E-31 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS00420 17cf4bee57f5725b4eb20910caf6c04e 641 Gene3D G3DSA:3.60.15.10 48 177 6.2E-31 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS00420 17cf4bee57f5725b4eb20910caf6c04e 641 PANTHER PTHR11935 34 175 2.3E-141 T 23-04-2016 DC74_RS00420 17cf4bee57f5725b4eb20910caf6c04e 641 PANTHER PTHR11935 199 448 2.3E-141 T 23-04-2016 DC74_RS00420 17cf4bee57f5725b4eb20910caf6c04e 641 SUPERFAMILY SSF55718 516 641 1.32E-18 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS00420 17cf4bee57f5725b4eb20910caf6c04e 641 SMART SM00849 83 313 1.8E-16 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS00420 17cf4bee57f5725b4eb20910caf6c04e 641 Pfam PF14863 Alkyl sulfatase dimerisation 354 497 2.1E-57 T 23-04-2016 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 DC74_RS00420 17cf4bee57f5725b4eb20910caf6c04e 641 Pfam PF00753 Metallo-beta-lactamase superfamily 80 313 1.4E-21 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS00420 17cf4bee57f5725b4eb20910caf6c04e 641 PANTHER PTHR11935:SF93 34 175 2.3E-141 T 23-04-2016 DC74_RS00420 17cf4bee57f5725b4eb20910caf6c04e 641 PANTHER PTHR11935:SF93 199 448 2.3E-141 T 23-04-2016 DC74_RS00420 17cf4bee57f5725b4eb20910caf6c04e 641 Pfam PF14864 Alkyl sulfatase C-terminal 513 641 5.0E-28 T 23-04-2016 IPR029229 Alkyl sulfatase, C-terminal DC74_RS00420 17cf4bee57f5725b4eb20910caf6c04e 641 SUPERFAMILY SSF56281 32 498 3.55E-122 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS33420 1d9a75e61684beb18b13365a43cec500 436 PANTHER PTHR23518 1 420 4.3E-63 T 23-04-2016 DC74_RS33420 1d9a75e61684beb18b13365a43cec500 436 Gene3D G3DSA:1.20.1250.20 23 209 4.0E-16 T 23-04-2016 DC74_RS33420 1d9a75e61684beb18b13365a43cec500 436 Gene3D G3DSA:1.20.1250.20 231 410 4.7E-17 T 23-04-2016 DC74_RS33420 1d9a75e61684beb18b13365a43cec500 436 PANTHER PTHR23518:SF2 1 420 4.3E-63 T 23-04-2016 DC74_RS33420 1d9a75e61684beb18b13365a43cec500 436 SUPERFAMILY SSF103473 23 410 4.19E-43 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS33420 1d9a75e61684beb18b13365a43cec500 436 Pfam PF07690 Major Facilitator Superfamily 30 268 3.4E-17 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS33420 1d9a75e61684beb18b13365a43cec500 436 Pfam PF07690 Major Facilitator Superfamily 271 423 4.1E-12 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS10845 41790030be34d176382966674ada3357 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 1.5E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10845 41790030be34d176382966674ada3357 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 1.5E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10845 41790030be34d176382966674ada3357 234 PANTHER PTHR30055 13 210 2.0E-40 T 23-04-2016 DC74_RS10845 41790030be34d176382966674ada3357 234 ProSitePatterns PS01081 TetR-type HTH domain signature. 42 72 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS10845 41790030be34d176382966674ada3357 234 Gene3D G3DSA:1.10.357.10 69 215 1.0E-22 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS10845 41790030be34d176382966674ada3357 234 PANTHER PTHR30055:SF80 13 210 2.0E-40 T 23-04-2016 DC74_RS10845 41790030be34d176382966674ada3357 234 SUPERFAMILY SSF46689 17 96 7.09E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS10845 41790030be34d176382966674ada3357 234 Gene3D G3DSA:1.10.10.60 18 68 2.3E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS10845 41790030be34d176382966674ada3357 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 70 3.1E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS16255 a5c9b676669802a04e4a1a2a8b73836a 436 PANTHER PTHR30383:SF3 70 425 1.1E-98 T 23-04-2016 DC74_RS16255 a5c9b676669802a04e4a1a2a8b73836a 436 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 226 418 1.3E-24 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS16255 a5c9b676669802a04e4a1a2a8b73836a 436 PANTHER PTHR30383 70 425 1.1E-98 T 23-04-2016 DC74_RS16255 a5c9b676669802a04e4a1a2a8b73836a 436 SUPERFAMILY SSF52266 220 423 8.7E-43 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS16255 a5c9b676669802a04e4a1a2a8b73836a 436 Gene3D G3DSA:3.40.50.1110 224 426 1.0E-31 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS02245 9c004652f805bde68584c10191e3ee33 327 Gene3D G3DSA:1.10.10.10 265 327 5.0E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02245 9c004652f805bde68584c10191e3ee33 327 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 62 1.3E-6 T 23-04-2016 IPR002831 Transcription regulator TrmB, N-terminal DC74_RS02245 9c004652f805bde68584c10191e3ee33 327 Pfam PF12840 Helix-turn-helix domain 267 310 8.7E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02245 9c004652f805bde68584c10191e3ee33 327 SMART SM00421 264 321 8.0E-4 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02245 9c004652f805bde68584c10191e3ee33 327 Gene3D G3DSA:1.10.10.10 8 62 2.0E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02245 9c004652f805bde68584c10191e3ee33 327 SUPERFAMILY SSF46894 261 327 1.19E-9 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS37820 d63b2aa77fe3fd48d1498cf86f4a9909 314 Gene3D G3DSA:3.90.550.10 1 255 2.0E-46 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS37820 d63b2aa77fe3fd48d1498cf86f4a9909 314 SUPERFAMILY SSF53448 1 253 8.89E-48 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS37820 d63b2aa77fe3fd48d1498cf86f4a9909 314 PANTHER PTHR22916 1 145 3.9E-41 T 23-04-2016 DC74_RS37820 d63b2aa77fe3fd48d1498cf86f4a9909 314 PANTHER PTHR22916 166 305 3.9E-41 T 23-04-2016 DC74_RS37820 d63b2aa77fe3fd48d1498cf86f4a9909 314 Pfam PF02709 N-terminal domain of galactosyltransferase 171 227 1.3E-8 T 23-04-2016 IPR027791 Galactosyltransferase, C-terminal UniPathway: UPA00378 DC74_RS37820 d63b2aa77fe3fd48d1498cf86f4a9909 314 Pfam PF00535 Glycosyl transferase family 2 4 140 2.3E-24 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS07265 351c4c667e06404aba3eb499be505881 150 PANTHER PTHR26402:SF531 60 146 3.5E-22 T 23-04-2016 DC74_RS07265 351c4c667e06404aba3eb499be505881 150 SUPERFAMILY SSF46894 55 146 5.59E-24 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS07265 351c4c667e06404aba3eb499be505881 150 SMART SM00862 73 146 8.6E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS07265 351c4c667e06404aba3eb499be505881 150 Pfam PF00486 Transcriptional regulatory protein, C terminal 73 145 7.5E-21 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS07265 351c4c667e06404aba3eb499be505881 150 PANTHER PTHR26402 60 146 3.5E-22 T 23-04-2016 DC74_RS07265 351c4c667e06404aba3eb499be505881 150 Gene3D G3DSA:1.10.10.10 57 146 3.7E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32060 bbccae948d2bb8cfc07bdf427023fb9b 227 SMART SM00345 24 82 1.6E-16 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS32060 bbccae948d2bb8cfc07bdf427023fb9b 227 PANTHER PTHR11751:SF403 18 108 2.4E-47 T 23-04-2016 DC74_RS32060 bbccae948d2bb8cfc07bdf427023fb9b 227 SMART SM00895 92 214 4.5E-22 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS32060 bbccae948d2bb8cfc07bdf427023fb9b 227 SUPERFAMILY SSF46785 14 110 1.08E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32060 bbccae948d2bb8cfc07bdf427023fb9b 227 Gene3D G3DSA:1.10.10.10 12 83 6.4E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32060 bbccae948d2bb8cfc07bdf427023fb9b 227 SUPERFAMILY SSF48008 89 220 2.25E-27 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS32060 bbccae948d2bb8cfc07bdf427023fb9b 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 82 8.0E-19 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS32060 bbccae948d2bb8cfc07bdf427023fb9b 227 Gene3D G3DSA:1.20.120.530 85 221 6.4E-30 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS32060 bbccae948d2bb8cfc07bdf427023fb9b 227 Pfam PF07729 FCD domain 92 213 5.6E-27 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS32060 bbccae948d2bb8cfc07bdf427023fb9b 227 PANTHER PTHR11751 18 108 2.4E-47 T 23-04-2016 DC74_RS05485 4d3d4931ed172590a39471620821b160 411 Gene3D G3DSA:3.40.50.150 87 255 8.6E-22 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS05485 4d3d4931ed172590a39471620821b160 411 Pfam PF08421 Putative zinc binding domain 4 65 2.9E-21 T 23-04-2016 IPR013630 Methyltransferase putative zinc binding domain KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.-|UniPathway: UPA00853 DC74_RS05485 4d3d4931ed172590a39471620821b160 411 Pfam PF08484 C-methyltransferase C-terminal domain 244 402 4.4E-63 T 23-04-2016 IPR013691 C-methyltransferase KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.-|UniPathway: UPA00853 DC74_RS05485 4d3d4931ed172590a39471620821b160 411 PANTHER PTHR10108 29 292 3.1E-35 T 23-04-2016 DC74_RS05485 4d3d4931ed172590a39471620821b160 411 PANTHER PTHR10108:SF714 29 292 3.1E-35 T 23-04-2016 DC74_RS05485 4d3d4931ed172590a39471620821b160 411 SUPERFAMILY SSF53335 61 250 5.63E-23 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS05485 4d3d4931ed172590a39471620821b160 411 Pfam PF13489 Methyltransferase domain 81 238 2.4E-13 T 23-04-2016 DC74_RS13265 648695c3871bccec3ef6d0792ecc9abb 285 PANTHER PTHR31310 41 259 2.9E-60 T 23-04-2016 DC74_RS13265 648695c3871bccec3ef6d0792ecc9abb 285 Pfam PF14378 PAP2 superfamily 77 257 2.6E-46 T 23-04-2016 IPR026841 Inositolphosphotransferase Aur1/Ipt1 DC74_RS13265 648695c3871bccec3ef6d0792ecc9abb 285 PANTHER PTHR31310:SF6 41 259 2.9E-60 T 23-04-2016 DC74_RS05900 a1a125b91eba102a0a57e5f5a3b350a9 341 Pfam PF00248 Aldo/keto reductase family 24 318 1.8E-61 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS05900 a1a125b91eba102a0a57e5f5a3b350a9 341 Gene3D G3DSA:3.20.20.100 10 331 1.2E-93 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS05900 a1a125b91eba102a0a57e5f5a3b350a9 341 SUPERFAMILY SSF51430 11 320 1.7E-84 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS05900 a1a125b91eba102a0a57e5f5a3b350a9 341 PANTHER PTHR11732 8 340 6.3E-144 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS05900 a1a125b91eba102a0a57e5f5a3b350a9 341 PANTHER PTHR11732:SF225 8 340 6.3E-144 T 23-04-2016 DC74_RS16185 cb43ddd81305fc04f882c56e7588deca 353 TIGRFAM TIGR03226 PhnU: 2-aminoethylphosphonate ABC transporter, permease protein 14 290 2.2E-91 T 23-04-2016 IPR017636 2-aminoethylphosphonate ABC transporter system, permease protein phnU GO:0016020|GO:0033223 DC74_RS16185 cb43ddd81305fc04f882c56e7588deca 353 PANTHER PTHR30193:SF20 1 297 5.7E-62 T 23-04-2016 DC74_RS16185 cb43ddd81305fc04f882c56e7588deca 353 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 285 1.0E-19 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16185 cb43ddd81305fc04f882c56e7588deca 353 PANTHER PTHR30193 1 297 5.7E-62 T 23-04-2016 DC74_RS16185 cb43ddd81305fc04f882c56e7588deca 353 Gene3D G3DSA:1.10.3720.10 25 289 4.7E-46 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16185 cb43ddd81305fc04f882c56e7588deca 353 SUPERFAMILY SSF161098 17 288 2.71E-50 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 SMART SM00220 11 286 3.0E-66 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 PANTHER PTHR24362:SF160 1 282 2.6E-110 T 23-04-2016 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 SUPERFAMILY SSF48452 373 503 7.91E-11 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 SUPERFAMILY SSF48452 534 656 1.26E-12 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 Pfam PF13424 Tetratricopeptide repeat 463 521 3.9E-9 T 23-04-2016 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 Pfam PF13424 Tetratricopeptide repeat 552 610 1.8E-8 T 23-04-2016 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 Gene3D G3DSA:1.10.510.10 83 276 2.8E-50 T 23-04-2016 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 Gene3D G3DSA:1.25.40.10 379 654 4.9E-20 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 Pfam PF00069 Protein kinase domain 11 269 7.7E-48 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 PANTHER PTHR24362 1 282 2.6E-110 T 23-04-2016 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 Pfam PF13374 Tetratricopeptide repeat 413 454 4.8E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 Pfam PF13374 Tetratricopeptide repeat 380 412 2.5E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 SUPERFAMILY SSF56112 4 298 2.26E-77 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS08455 35de8e82fc4ce31c765a7b7713362472 662 Gene3D G3DSA:3.30.200.20 4 82 6.5E-24 T 23-04-2016 DC74_RS20395 ad0bbe8454cc80bff3704cf4f9295f73 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 1.0E-7 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS20395 ad0bbe8454cc80bff3704cf4f9295f73 325 PANTHER PTHR11695:SF610 15 325 6.4E-155 T 23-04-2016 DC74_RS20395 ad0bbe8454cc80bff3704cf4f9295f73 325 Gene3D G3DSA:3.90.180.10 1 146 7.4E-51 T 23-04-2016 IPR011032 GroES-like DC74_RS20395 ad0bbe8454cc80bff3704cf4f9295f73 325 SUPERFAMILY SSF51735 111 287 1.45E-50 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20395 ad0bbe8454cc80bff3704cf4f9295f73 325 SUPERFAMILY SSF50129 1 140 1.29E-40 T 23-04-2016 IPR011032 GroES-like DC74_RS20395 ad0bbe8454cc80bff3704cf4f9295f73 325 Gene3D G3DSA:3.40.50.720 147 262 3.7E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20395 ad0bbe8454cc80bff3704cf4f9295f73 325 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 325 6.9E-144 T 23-04-2016 IPR014189 Quinone oxidoreductase PIG3 KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- DC74_RS20395 ad0bbe8454cc80bff3704cf4f9295f73 325 PANTHER PTHR11695 15 325 6.4E-155 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS20395 ad0bbe8454cc80bff3704cf4f9295f73 325 Pfam PF00107 Zinc-binding dehydrogenase 151 266 3.9E-30 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS20395 ad0bbe8454cc80bff3704cf4f9295f73 325 SMART SM00829 10 323 1.5E-50 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS17035 e9325a7c4d911c07afa3c8645036d593 574 PANTHER PTHR33392 55 572 3.2E-158 T 23-04-2016 DC74_RS17035 e9325a7c4d911c07afa3c8645036d593 574 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 172 332 1.1E-42 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS17035 e9325a7c4d911c07afa3c8645036d593 574 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 441 530 1.2E-9 T 23-04-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain DC74_RS17035 e9325a7c4d911c07afa3c8645036d593 574 PANTHER PTHR33392:SF7 55 572 3.2E-158 T 23-04-2016 DC74_RS17035 e9325a7c4d911c07afa3c8645036d593 574 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 172 332 4.9E-40 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS27965 5d870fe98629cfaca6eedef6eb7d0b53 272 Pfam PF08543 Phosphomethylpyrimidine kinase 14 263 6.8E-90 T 23-04-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 DC74_RS27965 5d870fe98629cfaca6eedef6eb7d0b53 272 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 264 1.7E-89 T 23-04-2016 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 DC74_RS27965 5d870fe98629cfaca6eedef6eb7d0b53 272 PANTHER PTHR20858:SF17 1 270 2.4E-115 T 23-04-2016 DC74_RS27965 5d870fe98629cfaca6eedef6eb7d0b53 272 PANTHER PTHR20858 1 270 2.4E-115 T 23-04-2016 DC74_RS27965 5d870fe98629cfaca6eedef6eb7d0b53 272 Gene3D G3DSA:3.40.1190.20 5 265 9.0E-99 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS27965 5d870fe98629cfaca6eedef6eb7d0b53 272 SUPERFAMILY SSF53613 3 267 1.39E-75 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS38865 29a8f5cbb89af6a06e4f87ffa78adba6 366 SUPERFAMILY SSF56801 65 317 3.89E-18 T 23-04-2016 DC74_RS38865 29a8f5cbb89af6a06e4f87ffa78adba6 366 Pfam PF00501 AMP-binding enzyme 91 316 2.3E-9 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS34100 4203b8045b09dfdf876826289af01c9a 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 261 2.4E-26 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS34100 4203b8045b09dfdf876826289af01c9a 273 Gene3D G3DSA:1.10.3720.10 69 263 2.3E-26 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS34100 4203b8045b09dfdf876826289af01c9a 273 PANTHER PTHR30151:SF22 32 270 6.2E-74 T 23-04-2016 DC74_RS34100 4203b8045b09dfdf876826289af01c9a 273 PANTHER PTHR30151 32 270 6.2E-74 T 23-04-2016 DC74_RS34100 4203b8045b09dfdf876826289af01c9a 273 SUPERFAMILY SSF161098 70 256 1.83E-34 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 Gene3D G3DSA:3.40.50.720 8 207 3.8E-56 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 PANTHER PTHR24322 153 178 5.6E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 PANTHER PTHR24322 13 137 5.6E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 SUPERFAMILY SSF51735 5 255 4.24E-58 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 Pfam PF00106 short chain dehydrogenase 9 195 1.2E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 5.0E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 5.0E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 5.0E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.0E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 188 5.7E-5 T 23-04-2016 DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.1E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 8.1E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17705 f4611c8910782c1b0a19bbed3e1cac83 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 8.1E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26300 a611b87ab9fd12f92e61e56c0120dfaa 290 PANTHER PTHR30151 16 290 1.8E-67 T 23-04-2016 DC74_RS26300 a611b87ab9fd12f92e61e56c0120dfaa 290 Gene3D G3DSA:1.10.3720.10 84 275 7.1E-23 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26300 a611b87ab9fd12f92e61e56c0120dfaa 290 SUPERFAMILY SSF161098 84 266 5.89E-31 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26300 a611b87ab9fd12f92e61e56c0120dfaa 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 272 2.9E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.9E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.9E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.9E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PANTHER PTHR24322 20 140 8.3E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PANTHER PTHR24322 156 188 8.3E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 Gene3D G3DSA:3.40.50.720 10 254 8.4E-69 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 253 9.2E-50 T 23-04-2016 DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PANTHER PTHR24322:SF390 20 140 8.3E-51 T 23-04-2016 DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PANTHER PTHR24322:SF390 156 188 8.3E-51 T 23-04-2016 DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.2E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 2.2E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.2E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.2E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.2E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.2E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21620 974a59bdaf33b65bc1af2025cd7feb74 258 SUPERFAMILY SSF51735 15 253 2.84E-67 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS25075 84c0aee47f377725f52ec44af3f42cb9 312 SUPERFAMILY SSF100950 64 223 1.26E-29 T 23-04-2016 DC74_RS25075 84c0aee47f377725f52ec44af3f42cb9 312 Gene3D G3DSA:3.40.50.1360 65 215 1.4E-13 T 23-04-2016 DC74_RS25075 84c0aee47f377725f52ec44af3f42cb9 312 SMART SM01134 61 222 7.8E-65 T 23-04-2016 DC74_RS25075 84c0aee47f377725f52ec44af3f42cb9 312 SUPERFAMILY SSF46785 3 47 4.12E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25075 84c0aee47f377725f52ec44af3f42cb9 312 PANTHER PTHR30363:SF13 1 292 3.0E-103 T 23-04-2016 DC74_RS25075 84c0aee47f377725f52ec44af3f42cb9 312 Pfam PF00455 DeoR C terminal sensor domain 64 221 3.0E-50 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain DC74_RS25075 84c0aee47f377725f52ec44af3f42cb9 312 SMART SM00420 1 46 2.6E-6 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS25075 84c0aee47f377725f52ec44af3f42cb9 312 Pfam PF08220 DeoR-like helix-turn-helix domain 1 46 3.7E-11 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS25075 84c0aee47f377725f52ec44af3f42cb9 312 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 44 5.5E-8 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS25075 84c0aee47f377725f52ec44af3f42cb9 312 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 12 26 5.5E-8 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS25075 84c0aee47f377725f52ec44af3f42cb9 312 Gene3D G3DSA:1.10.10.10 2 44 5.8E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25075 84c0aee47f377725f52ec44af3f42cb9 312 PANTHER PTHR30363 1 292 3.0E-103 T 23-04-2016 DC74_RS26120 10397776f5c97df2b31921d5910d36be 329 PANTHER PTHR30465:SF56 1 328 8.5E-92 T 23-04-2016 DC74_RS26120 10397776f5c97df2b31921d5910d36be 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 327 2.9E-36 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26120 10397776f5c97df2b31921d5910d36be 329 Gene3D G3DSA:1.10.3720.10 106 320 1.4E-16 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26120 10397776f5c97df2b31921d5910d36be 329 PANTHER PTHR30465 1 328 8.5E-92 T 23-04-2016 DC74_RS26120 10397776f5c97df2b31921d5910d36be 329 SUPERFAMILY SSF161098 107 310 5.63E-15 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS29740 f7b81399415a233a633538dc32755cee 266 Pfam PF00005 ABC transporter 25 175 5.8E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS29740 f7b81399415a233a633538dc32755cee 266 SMART SM00382 34 223 2.5E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS29740 f7b81399415a233a633538dc32755cee 266 Gene3D G3DSA:3.40.50.300 7 238 2.1E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29740 f7b81399415a233a633538dc32755cee 266 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS29740 f7b81399415a233a633538dc32755cee 266 PANTHER PTHR24220:SF575 11 223 2.0E-123 T 23-04-2016 DC74_RS29740 f7b81399415a233a633538dc32755cee 266 SUPERFAMILY SSF52540 8 229 2.09E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29740 f7b81399415a233a633538dc32755cee 266 PANTHER PTHR24220 11 223 2.0E-123 T 23-04-2016 DC74_RS16525 03a7ad1f5c7a62b535a7f4cad5d0a83a 261 PANTHER PTHR10046:SF48 103 255 3.5E-51 T 23-04-2016 DC74_RS16525 03a7ad1f5c7a62b535a7f4cad5d0a83a 261 SUPERFAMILY SSF54211 98 247 1.97E-20 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS16525 03a7ad1f5c7a62b535a7f4cad5d0a83a 261 PANTHER PTHR10046 103 255 3.5E-51 T 23-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 DC74_RS16525 03a7ad1f5c7a62b535a7f4cad5d0a83a 261 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 150 233 1.4E-6 T 23-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 DC74_RS16525 03a7ad1f5c7a62b535a7f4cad5d0a83a 261 Gene3D G3DSA:3.30.230.10 104 247 2.0E-23 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS29535 231a338eb79863a38e679bf40adb6ea2 409 Gene3D G3DSA:3.40.47.10 259 406 6.4E-49 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29535 231a338eb79863a38e679bf40adb6ea2 409 SMART SM00825 Beta-ketoacyl synthase 1 408 3.3E-14 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS29535 231a338eb79863a38e679bf40adb6ea2 409 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 150 166 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS29535 231a338eb79863a38e679bf40adb6ea2 409 SUPERFAMILY SSF53901 209 406 2.34E-60 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29535 231a338eb79863a38e679bf40adb6ea2 409 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 251 364 5.4E-32 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS29535 231a338eb79863a38e679bf40adb6ea2 409 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 242 1.1E-47 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS29535 231a338eb79863a38e679bf40adb6ea2 409 SUPERFAMILY SSF53901 1 247 9.03E-68 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29535 231a338eb79863a38e679bf40adb6ea2 409 Gene3D G3DSA:3.40.47.10 1 255 1.1E-65 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29535 231a338eb79863a38e679bf40adb6ea2 409 PANTHER PTHR11712 1 406 9.2E-143 T 23-04-2016 DC74_RS16345 c2eadb5d6edcb5ae75dcf44cb0144f3a 243 PANTHER PTHR11953 3 239 1.5E-85 T 23-04-2016 DC74_RS16345 c2eadb5d6edcb5ae75dcf44cb0144f3a 243 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 23-04-2016 IPR018336 Ribonuclease PH, conserved site DC74_RS16345 c2eadb5d6edcb5ae75dcf44cb0144f3a 243 Gene3D G3DSA:3.30.230.70 3 240 5.2E-31 T 23-04-2016 IPR027408 PNPase/RNase PH domain DC74_RS16345 c2eadb5d6edcb5ae75dcf44cb0144f3a 243 Hamap MF_00564 Ribonuclease PH [rph]. 2 240 47.216 T 23-04-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 DC74_RS16345 c2eadb5d6edcb5ae75dcf44cb0144f3a 243 Pfam PF03725 3' exoribonuclease family, domain 2 162 225 4.5E-10 T 23-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 DC74_RS16345 c2eadb5d6edcb5ae75dcf44cb0144f3a 243 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 239 8.9E-115 T 23-04-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 DC74_RS16345 c2eadb5d6edcb5ae75dcf44cb0144f3a 243 PANTHER PTHR11953:SF0 3 239 1.5E-85 T 23-04-2016 DC74_RS16345 c2eadb5d6edcb5ae75dcf44cb0144f3a 243 SUPERFAMILY SSF54211 3 183 2.63E-45 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS16345 c2eadb5d6edcb5ae75dcf44cb0144f3a 243 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 9.5E-24 T 23-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 DC74_RS16345 c2eadb5d6edcb5ae75dcf44cb0144f3a 243 SUPERFAMILY SSF55666 156 240 1.83E-24 T 23-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 DC74_RS04250 afa385f4b4e618d41d51a0a066479304 219 Pfam PF02469 Fasciclin domain 97 217 2.1E-29 T 23-04-2016 IPR000782 FAS1 domain DC74_RS04250 afa385f4b4e618d41d51a0a066479304 219 PANTHER PTHR10900 61 219 1.0E-43 T 23-04-2016 DC74_RS04250 afa385f4b4e618d41d51a0a066479304 219 SUPERFAMILY SSF82153 81 218 4.45E-34 T 23-04-2016 IPR000782 FAS1 domain DC74_RS04250 afa385f4b4e618d41d51a0a066479304 219 Gene3D G3DSA:2.30.180.10 87 218 5.8E-32 T 23-04-2016 IPR000782 FAS1 domain DC74_RS04250 afa385f4b4e618d41d51a0a066479304 219 SMART SM00554 121 218 8.4E-30 T 23-04-2016 IPR000782 FAS1 domain DC74_RS23325 a740f71e785664d2f94589f38982d0f6 134 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 5 90 9.7E-16 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS23325 a740f71e785664d2f94589f38982d0f6 134 PANTHER PTHR35176 1 132 1.1E-16 T 23-04-2016 DC74_RS23325 a740f71e785664d2f94589f38982d0f6 134 SUPERFAMILY SSF50475 5 131 3.21E-29 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS23325 a740f71e785664d2f94589f38982d0f6 134 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 10 132 2.7E-38 T 23-04-2016 IPR019920 F420-binding domain, putative DC74_RS23325 a740f71e785664d2f94589f38982d0f6 134 Gene3D G3DSA:2.30.110.10 5 132 2.0E-28 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS15065 4277a5ed5e02920f7d2c5a1c5c61d7d1 629 ProSitePatterns PS00455 Putative AMP-binding domain signature. 204 215 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS15065 4277a5ed5e02920f7d2c5a1c5c61d7d1 629 Gene3D G3DSA:3.40.50.980 211 301 5.6E-26 T 23-04-2016 DC74_RS15065 4277a5ed5e02920f7d2c5a1c5c61d7d1 629 Gene3D G3DSA:3.40.50.980 360 423 5.6E-26 T 23-04-2016 DC74_RS15065 4277a5ed5e02920f7d2c5a1c5c61d7d1 629 Gene3D G3DSA:3.40.50.980 189 210 3.2E-35 T 23-04-2016 DC74_RS15065 4277a5ed5e02920f7d2c5a1c5c61d7d1 629 Gene3D G3DSA:3.40.50.980 14 157 3.2E-35 T 23-04-2016 DC74_RS15065 4277a5ed5e02920f7d2c5a1c5c61d7d1 629 PANTHER PTHR24096:SF46 8 628 2.3E-174 T 23-04-2016 DC74_RS15065 4277a5ed5e02920f7d2c5a1c5c61d7d1 629 Gene3D G3DSA:2.30.38.10 424 487 2.6E-21 T 23-04-2016 DC74_RS15065 4277a5ed5e02920f7d2c5a1c5c61d7d1 629 SUPERFAMILY SSF56801 363 624 1.07E-118 T 23-04-2016 DC74_RS15065 4277a5ed5e02920f7d2c5a1c5c61d7d1 629 SUPERFAMILY SSF56801 6 306 1.07E-118 T 23-04-2016 DC74_RS15065 4277a5ed5e02920f7d2c5a1c5c61d7d1 629 Pfam PF00501 AMP-binding enzyme 21 493 6.4E-97 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS15065 4277a5ed5e02920f7d2c5a1c5c61d7d1 629 PANTHER PTHR24096 8 628 2.3E-174 T 23-04-2016 DC74_RS08925 1d40f3a6a60f6e6df6eb9df6cfc5a8b6 356 PANTHER PTHR10289 1 356 6.7E-163 T 23-04-2016 DC74_RS08925 1d40f3a6a60f6e6df6eb9df6cfc5a8b6 356 Pfam PF01212 Beta-eliminating lyase 19 304 1.1E-53 T 23-04-2016 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 DC74_RS08925 1d40f3a6a60f6e6df6eb9df6cfc5a8b6 356 Gene3D G3DSA:3.40.640.10 10 263 2.2E-58 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS08925 1d40f3a6a60f6e6df6eb9df6cfc5a8b6 356 SUPERFAMILY SSF53383 18 352 1.24E-91 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS08925 1d40f3a6a60f6e6df6eb9df6cfc5a8b6 356 PANTHER PTHR10289:SF8 1 356 6.7E-163 T 23-04-2016 DC74_RS08925 1d40f3a6a60f6e6df6eb9df6cfc5a8b6 356 Gene3D G3DSA:3.90.1150.10 266 351 2.3E-26 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS38880 f79840f6038b25e7ef06a306b624a291 480 PANTHER PTHR24567 294 477 3.1E-150 T 23-04-2016 DC74_RS38880 f79840f6038b25e7ef06a306b624a291 480 PANTHER PTHR24567 20 226 3.1E-150 T 23-04-2016 DC74_RS38880 f79840f6038b25e7ef06a306b624a291 480 PANTHER PTHR24567:SF37 294 477 3.1E-150 T 23-04-2016 DC74_RS38880 f79840f6038b25e7ef06a306b624a291 480 SUPERFAMILY SSF51206 94 233 4.58E-20 T 23-04-2016 IPR018490 Cyclic nucleotide-binding-like DC74_RS38880 f79840f6038b25e7ef06a306b624a291 480 Gene3D G3DSA:2.60.120.10 96 233 1.0E-18 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS38880 f79840f6038b25e7ef06a306b624a291 480 Pfam PF00027 Cyclic nucleotide-binding domain 125 211 2.0E-12 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS38880 f79840f6038b25e7ef06a306b624a291 480 PANTHER PTHR24567:SF37 20 226 3.1E-150 T 23-04-2016 DC74_RS38880 f79840f6038b25e7ef06a306b624a291 480 SMART SM00100 105 228 6.1E-5 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS39245 32eea6a7e98878142b713b9fd7803edf 189 PANTHER PTHR11002:SF17 1 185 2.5E-59 T 23-04-2016 DC74_RS39245 32eea6a7e98878142b713b9fd7803edf 189 Pfam PF00484 Carbonic anhydrase 35 181 2.1E-29 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS39245 32eea6a7e98878142b713b9fd7803edf 189 SMART SM00947 26 185 1.6E-31 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS39245 32eea6a7e98878142b713b9fd7803edf 189 PANTHER PTHR11002 1 185 2.5E-59 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS39245 32eea6a7e98878142b713b9fd7803edf 189 SUPERFAMILY SSF53056 2 185 3.27E-39 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS39245 32eea6a7e98878142b713b9fd7803edf 189 Gene3D G3DSA:3.40.1050.10 2 187 7.5E-40 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 SUPERFAMILY SSF103473 487 515 1.57E-63 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 SUPERFAMILY SSF103473 23 215 1.57E-63 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 SUPERFAMILY SSF103473 264 435 1.57E-63 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 PANTHER PTHR23501 24 529 7.1E-201 T 23-04-2016 DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 Gene3D G3DSA:1.20.1250.20 28 210 6.5E-33 T 23-04-2016 DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 Gene3D G3DSA:1.20.1250.20 280 436 5.4E-17 T 23-04-2016 DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 Gene3D G3DSA:1.20.1250.20 488 519 5.4E-17 T 23-04-2016 DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 PRINTS PR01036 Tetracycline resistance protein TetB signature 416 435 9.0E-10 T 23-04-2016 DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 PRINTS PR01036 Tetracycline resistance protein TetB signature 372 392 9.0E-10 T 23-04-2016 DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 PRINTS PR01036 Tetracycline resistance protein TetB signature 153 177 9.0E-10 T 23-04-2016 DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 PRINTS PR01036 Tetracycline resistance protein TetB signature 31 55 9.0E-10 T 23-04-2016 DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 Pfam PF07690 Major Facilitator Superfamily 33 425 2.4E-44 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS10950 cd5fdd9a5ffc0c72f775be25f3814142 547 PANTHER PTHR23501:SF65 24 529 7.1E-201 T 23-04-2016 DC74_RS14145 57908908249411faaa7946da72c63669 407 PANTHER PTHR12526 52 395 6.3E-49 T 23-04-2016 DC74_RS14145 57908908249411faaa7946da72c63669 407 SUPERFAMILY SSF53756 65 395 2.79E-60 T 23-04-2016 DC74_RS14145 57908908249411faaa7946da72c63669 407 Gene3D G3DSA:3.40.50.2000 229 360 2.5E-25 T 23-04-2016 DC74_RS14145 57908908249411faaa7946da72c63669 407 Pfam PF00534 Glycosyl transferases group 1 229 353 1.4E-22 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 DC74_RS14145 57908908249411faaa7946da72c63669 407 Pfam PF13439 Glycosyltransferase Family 4 68 220 3.0E-14 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain DC74_RS01375 9890bfdfca1e89de3e67c0999459223c 485 Pfam PF00135 Carboxylesterase family 4 461 1.7E-90 T 23-04-2016 IPR002018 Carboxylesterase, type B DC74_RS01375 9890bfdfca1e89de3e67c0999459223c 485 PANTHER PTHR11559:SF142 2 459 5.4E-119 T 23-04-2016 DC74_RS01375 9890bfdfca1e89de3e67c0999459223c 485 SUPERFAMILY SSF53474 2 463 1.69E-99 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01375 9890bfdfca1e89de3e67c0999459223c 485 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 176 191 - T 23-04-2016 IPR019826 Carboxylesterase type B, active site DC74_RS01375 9890bfdfca1e89de3e67c0999459223c 485 Gene3D G3DSA:3.40.50.1820 2 464 1.8E-115 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01375 9890bfdfca1e89de3e67c0999459223c 485 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 105 121 - T 23-04-2016 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 DC74_RS01375 9890bfdfca1e89de3e67c0999459223c 485 PANTHER PTHR11559 2 459 5.4E-119 T 23-04-2016 DC74_RS17415 303c547dc040d164093ea37f0bc22655 213 SUPERFAMILY SSF109998 33 163 3.92E-13 T 23-04-2016 IPR027304 Trigger factor/SurA domain DC74_RS17415 303c547dc040d164093ea37f0bc22655 213 Pfam PF13624 SurA N-terminal domain 21 147 2.9E-10 T 23-04-2016 DC74_RS34975 7e7d43723e984cecd51a712bb7fc0f9c 292 Pfam PF01183 Glycosyl hydrolases family 25 85 269 1.3E-49 T 23-04-2016 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 DC74_RS34975 7e7d43723e984cecd51a712bb7fc0f9c 292 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 86 119 - T 23-04-2016 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 DC74_RS34975 7e7d43723e984cecd51a712bb7fc0f9c 292 PANTHER PTHR34135:SF2 84 277 9.0E-66 T 23-04-2016 DC74_RS34975 7e7d43723e984cecd51a712bb7fc0f9c 292 SUPERFAMILY SSF51445 79 284 1.12E-62 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS34975 7e7d43723e984cecd51a712bb7fc0f9c 292 SMART SM00641 82 191 7.3E-43 T 23-04-2016 IPR018077 Glycoside hydrolase, family 25 subgroup DC74_RS34975 7e7d43723e984cecd51a712bb7fc0f9c 292 PANTHER PTHR34135 84 277 9.0E-66 T 23-04-2016 DC74_RS34975 7e7d43723e984cecd51a712bb7fc0f9c 292 Gene3D G3DSA:3.20.20.80 82 285 1.4E-67 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS25615 1058e6a9634ddf4c1e6ed25fa7e9ecdc 343 PANTHER PTHR30447:SF0 10 340 2.1E-179 T 23-04-2016 DC74_RS25615 1058e6a9634ddf4c1e6ed25fa7e9ecdc 343 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 19 330 7.5E-116 T 23-04-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 DC74_RS25615 1058e6a9634ddf4c1e6ed25fa7e9ecdc 343 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 19 326 1.3E-141 T 23-04-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 DC74_RS25615 1058e6a9634ddf4c1e6ed25fa7e9ecdc 343 PANTHER PTHR30447 10 340 2.1E-179 T 23-04-2016 DC74_RS25615 1058e6a9634ddf4c1e6ed25fa7e9ecdc 343 SUPERFAMILY SSF56655 17 329 7.32E-110 T 23-04-2016 DC74_RS25615 1058e6a9634ddf4c1e6ed25fa7e9ecdc 343 PIRSF PIRSF004532 17 337 6.6E-145 T 23-04-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 DC74_RS25615 1058e6a9634ddf4c1e6ed25fa7e9ecdc 343 Gene3D G3DSA:3.30.540.10 17 190 6.9E-64 T 23-04-2016 DC74_RS25615 1058e6a9634ddf4c1e6ed25fa7e9ecdc 343 Gene3D G3DSA:3.30.540.10 191 337 1.7E-45 T 23-04-2016 DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 136 324 4.3E-51 T 23-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 338 34.179 T 23-04-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 2 338 2.3E-133 T 23-04-2016 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 Gene3D G3DSA:3.30.360.10 139 320 7.0E-71 T 23-04-2016 DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 PANTHER PTHR10174 48 342 6.0E-62 T 23-04-2016 DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 SUPERFAMILY SSF51735 1 153 1.11E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 115 8.4E-31 T 23-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 PANTHER PTHR10174:SF2 48 342 6.0E-62 T 23-04-2016 DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 PIRSF PIRSF000148 1 342 1.6E-110 T 23-04-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 SUPERFAMILY SSF55347 126 325 3.4E-61 T 23-04-2016 DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 241 255 - T 23-04-2016 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 Gene3D G3DSA:3.40.50.720 1 138 1.0E-59 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15420 e3695fd2cbea71a9dff521522f32e25b 343 SMART SM00859 2 117 2.9E-39 T 23-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DC74_RS20715 839ce53812f129273bfdbc5d58760092 168 Gene3D G3DSA:3.30.300.120 18 99 6.2E-22 T 23-04-2016 DC74_RS20715 839ce53812f129273bfdbc5d58760092 168 Gene3D G3DSA:3.30.1370.50 101 167 6.2E-24 T 23-04-2016 IPR001374 R3H domain GO:0003676 DC74_RS20715 839ce53812f129273bfdbc5d58760092 168 SMART SM00393 90 168 2.0E-27 T 23-04-2016 IPR001374 R3H domain GO:0003676 DC74_RS20715 839ce53812f129273bfdbc5d58760092 168 PANTHER PTHR20953:SF0 8 168 1.5E-96 T 23-04-2016 DC74_RS20715 839ce53812f129273bfdbc5d58760092 168 PANTHER PTHR20953 8 168 1.5E-96 T 23-04-2016 DC74_RS20715 839ce53812f129273bfdbc5d58760092 168 Pfam PF01424 R3H domain 109 165 1.2E-16 T 23-04-2016 IPR001374 R3H domain GO:0003676 DC74_RS20715 839ce53812f129273bfdbc5d58760092 168 SUPERFAMILY SSF82708 122 167 9.22E-12 T 23-04-2016 IPR001374 R3H domain GO:0003676 DC74_RS27465 07451e3bc90a4153507ede8f4a31a451 125 PANTHER PTHR11715 1 122 1.0E-56 T 23-04-2016 IPR002930 Glycine cleavage system H-protein DC74_RS27465 07451e3bc90a4153507ede8f4a31a451 125 Gene3D G3DSA:2.40.50.100 6 123 7.2E-45 T 23-04-2016 DC74_RS27465 07451e3bc90a4153507ede8f4a31a451 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 123 1.8E-44 T 23-04-2016 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 DC74_RS27465 07451e3bc90a4153507ede8f4a31a451 125 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 48 77 - T 23-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site DC74_RS27465 07451e3bc90a4153507ede8f4a31a451 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 124 28.506 T 23-04-2016 IPR002930 Glycine cleavage system H-protein DC74_RS27465 07451e3bc90a4153507ede8f4a31a451 125 SUPERFAMILY SSF51230 4 123 2.36E-38 T 23-04-2016 IPR011053 Single hybrid motif DC74_RS27465 07451e3bc90a4153507ede8f4a31a451 125 Pfam PF01597 Glycine cleavage H-protein 7 122 8.1E-41 T 23-04-2016 IPR002930 Glycine cleavage system H-protein DC74_RS06310 648bc50866d2503ef1f0ecb1bf4cc4bc 541 Gene3D G3DSA:3.40.50.300 248 399 3.3E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06310 648bc50866d2503ef1f0ecb1bf4cc4bc 541 PANTHER PTHR24031 32 460 1.2E-199 T 23-04-2016 DC74_RS06310 648bc50866d2503ef1f0ecb1bf4cc4bc 541 SUPERFAMILY SSF52540 111 391 3.56E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06310 648bc50866d2503ef1f0ecb1bf4cc4bc 541 Pfam PF00271 Helicase conserved C-terminal domain 277 374 2.1E-24 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS06310 648bc50866d2503ef1f0ecb1bf4cc4bc 541 SMART SM00490 293 374 2.4E-28 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS06310 648bc50866d2503ef1f0ecb1bf4cc4bc 541 Pfam PF00270 DEAD/DEAH box helicase 63 231 3.0E-44 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS06310 648bc50866d2503ef1f0ecb1bf4cc4bc 541 PANTHER PTHR24031:SF334 32 460 1.2E-199 T 23-04-2016 DC74_RS06310 648bc50866d2503ef1f0ecb1bf4cc4bc 541 Gene3D G3DSA:3.40.50.300 34 247 1.0E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06310 648bc50866d2503ef1f0ecb1bf4cc4bc 541 SMART SM00487 58 258 3.3E-50 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS32535 8547b645ccc3475970e89206f3d81784 232 SUPERFAMILY SSF53335 39 167 7.87E-17 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS32535 8547b645ccc3475970e89206f3d81784 232 Pfam PF13578 Methyltransferase domain 63 164 2.2E-16 T 23-04-2016 DC74_RS32535 8547b645ccc3475970e89206f3d81784 232 Gene3D G3DSA:3.40.50.150 16 139 1.0E-14 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS37890 7cdbf06674beb90fa210a034e10dc9f6 327 Pfam PF08279 HTH domain 5 60 9.3E-14 T 23-04-2016 IPR013196 Helix-turn-helix, type 11 DC74_RS37890 7cdbf06674beb90fa210a034e10dc9f6 327 PANTHER PTHR30595:SF4 1 309 2.6E-56 T 23-04-2016 DC74_RS37890 7cdbf06674beb90fa210a034e10dc9f6 327 Gene3D G3DSA:1.10.10.10 1 63 2.8E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37890 7cdbf06674beb90fa210a034e10dc9f6 327 PANTHER PTHR30595 1 309 2.6E-56 T 23-04-2016 DC74_RS37890 7cdbf06674beb90fa210a034e10dc9f6 327 SUPERFAMILY SSF46785 2 62 4.81E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37890 7cdbf06674beb90fa210a034e10dc9f6 327 Pfam PF13280 WYL domain 140 315 9.0E-38 T 23-04-2016 IPR026881 WYL domain DC74_RS13945 23237304496936925b93358f2d9f543b 152 PANTHER PTHR10681 2 152 2.4E-50 T 23-04-2016 DC74_RS13945 23237304496936925b93358f2d9f543b 152 SUPERFAMILY SSF52833 1 152 4.16E-48 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS13945 23237304496936925b93358f2d9f543b 152 Gene3D G3DSA:3.40.30.10 2 152 1.5E-49 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS13945 23237304496936925b93358f2d9f543b 152 PANTHER PTHR10681:SF121 2 152 2.4E-50 T 23-04-2016 DC74_RS13945 23237304496936925b93358f2d9f543b 152 PIRSF PIRSF000239 1 152 1.0E-28 T 23-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 DC74_RS13945 23237304496936925b93358f2d9f543b 152 Pfam PF00578 AhpC/TSA family 5 130 1.8E-38 T 23-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS00650 9f7d91430cc3b5d025514aec9aeecbe7 497 PIRSF PIRSF006060 7 483 4.2E-60 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS00650 9f7d91430cc3b5d025514aec9aeecbe7 497 PANTHER PTHR11785:SF366 18 493 4.0E-78 T 23-04-2016 DC74_RS00650 9f7d91430cc3b5d025514aec9aeecbe7 497 Pfam PF13520 Amino acid permease 31 456 4.3E-39 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS00650 9f7d91430cc3b5d025514aec9aeecbe7 497 PANTHER PTHR11785 18 493 4.0E-78 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS37080 1408a4e848a7fc0c209044a4813cc5a7 172 SUPERFAMILY SSF53901 20 152 3.41E-7 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS37080 1408a4e848a7fc0c209044a4813cc5a7 172 Gene3D G3DSA:3.40.47.10 32 149 6.7E-4 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS37080 1408a4e848a7fc0c209044a4813cc5a7 172 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 161 5.6E-6 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS30470 7e07ccb9b74ef83ee8f6d9fd919d838c 227 PANTHER PTHR22916:SF23 1 222 3.8E-14 T 23-04-2016 DC74_RS30470 7e07ccb9b74ef83ee8f6d9fd919d838c 227 PANTHER PTHR22916 1 222 3.8E-14 T 23-04-2016 DC74_RS30470 7e07ccb9b74ef83ee8f6d9fd919d838c 227 SUPERFAMILY SSF53448 3 193 2.25E-16 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS30470 7e07ccb9b74ef83ee8f6d9fd919d838c 227 Gene3D G3DSA:3.90.550.10 5 209 1.3E-15 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 369 2.3E-26 T 23-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 SUPERFAMILY SSF53738 261 365 3.57E-31 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 219 4.4E-22 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 4.4E-22 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 4.4E-22 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 4.4E-22 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 SUPERFAMILY SSF53738 6 167 9.42E-29 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 255 2.7E-24 T 23-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 SUPERFAMILY SSF55957 369 451 3.66E-20 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 PANTHER PTHR22573:SF28 6 451 1.3E-168 T 23-04-2016 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 Gene3D G3DSA:3.40.120.10 252 369 8.5E-39 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 Gene3D G3DSA:3.40.120.10 174 251 1.5E-30 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 SUPERFAMILY SSF53738 155 257 1.92E-29 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 Gene3D G3DSA:3.30.310.50 371 451 1.9E-21 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 450 1.5E-14 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 Gene3D G3DSA:3.40.120.10 8 121 7.1E-24 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 PANTHER PTHR22573 6 451 1.3E-168 T 23-04-2016 DC74_RS16965 b0097af87b7bb54841fd529523edc47c 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 6 133 2.8E-27 T 23-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS01910 995a505859a1528b199b6b2c08c99249 343 PANTHER PTHR30011 5 325 1.2E-27 T 23-04-2016 DC74_RS01910 995a505859a1528b199b6b2c08c99249 343 TIGRFAM TIGR04020 seco_metab_LLM: natural product biosynthesis luciferase-like monooxygenase domain 3 339 2.6E-138 T 23-04-2016 IPR024011 Natural product biosynthesis luciferase-like monooxygenase domain DC74_RS01910 995a505859a1528b199b6b2c08c99249 343 SUPERFAMILY SSF51679 3 337 8.72E-66 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS01910 995a505859a1528b199b6b2c08c99249 343 Pfam PF00296 Luciferase-like monooxygenase 14 313 2.8E-44 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS01910 995a505859a1528b199b6b2c08c99249 343 Gene3D G3DSA:3.20.20.30 4 337 6.4E-69 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS35460 35c977224ef30477a8ed0d09e2f56723 173 SUPERFAMILY SSF46785 11 151 1.45E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35460 35c977224ef30477a8ed0d09e2f56723 173 Gene3D G3DSA:1.10.10.10 10 149 1.3E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35460 35c977224ef30477a8ed0d09e2f56723 173 PANTHER PTHR33164:SF10 40 160 7.5E-38 T 23-04-2016 DC74_RS35460 35c977224ef30477a8ed0d09e2f56723 173 PANTHER PTHR33164 40 160 7.5E-38 T 23-04-2016 DC74_RS35460 35c977224ef30477a8ed0d09e2f56723 173 SMART SM00347 36 136 1.0E-17 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS35460 35c977224ef30477a8ed0d09e2f56723 173 Pfam PF01047 MarR family 44 100 2.2E-13 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS25545 f3401e59b51071f7270f6e189630daa1 314 PANTHER PTHR10264:SF46 66 251 9.1E-67 T 23-04-2016 DC74_RS25545 f3401e59b51071f7270f6e189630daa1 314 PANTHER PTHR10264:SF46 274 289 9.1E-67 T 23-04-2016 DC74_RS25545 f3401e59b51071f7270f6e189630daa1 314 SUPERFAMILY SSF117892 118 248 1.1E-6 T 23-04-2016 IPR001107 Band 7 domain DC74_RS25545 f3401e59b51071f7270f6e189630daa1 314 PANTHER PTHR10264 66 251 9.1E-67 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS25545 f3401e59b51071f7270f6e189630daa1 314 PANTHER PTHR10264 274 289 9.1E-67 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS25545 f3401e59b51071f7270f6e189630daa1 314 Pfam PF01145 SPFH domain / Band 7 family 86 259 2.5E-23 T 23-04-2016 IPR001107 Band 7 domain DC74_RS25545 f3401e59b51071f7270f6e189630daa1 314 SMART SM00244 82 246 1.1E-7 T 23-04-2016 IPR001107 Band 7 domain DC74_RS16755 464f2c24e7393916cc2832618df97c5a 328 PANTHER PTHR10366:SF39 2 315 1.8E-97 T 23-04-2016 DC74_RS16755 464f2c24e7393916cc2832618df97c5a 328 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 324 1.4E-100 T 23-04-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|UniPathway: UPA00214 DC74_RS16755 464f2c24e7393916cc2832618df97c5a 328 SUPERFAMILY SSF51735 1 321 1.55E-87 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16755 464f2c24e7393916cc2832618df97c5a 328 Gene3D G3DSA:3.40.50.720 1 169 1.1E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16755 464f2c24e7393916cc2832618df97c5a 328 Gene3D G3DSA:3.90.25.10 252 323 2.3E-35 T 23-04-2016 DC74_RS16755 464f2c24e7393916cc2832618df97c5a 328 Gene3D G3DSA:3.90.25.10 170 218 2.3E-35 T 23-04-2016 DC74_RS16755 464f2c24e7393916cc2832618df97c5a 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 249 5.8E-54 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS16755 464f2c24e7393916cc2832618df97c5a 328 PANTHER PTHR10366 2 315 1.8E-97 T 23-04-2016 DC74_RS07830 77be5517b039ad79565b7fff80af8563 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 132 7.2E-16 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS07830 77be5517b039ad79565b7fff80af8563 136 PANTHER PTHR21366 1 134 1.3E-52 T 23-04-2016 DC74_RS07830 77be5517b039ad79565b7fff80af8563 136 SUPERFAMILY SSF54593 3 134 3.62E-25 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS07830 77be5517b039ad79565b7fff80af8563 136 PANTHER PTHR21366:SF12 1 134 1.3E-52 T 23-04-2016 DC74_RS07830 77be5517b039ad79565b7fff80af8563 136 Gene3D G3DSA:3.10.180.10 1 134 7.4E-29 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 Pfam PF00990 Diguanylate cyclase, GGDEF domain 433 556 4.3E-32 T 23-04-2016 IPR000160 GGDEF domain DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 PANTHER PTHR10799:SF774 435 559 2.7E-30 T 23-04-2016 DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 SMART SM00091 213 283 3.3E-5 T 23-04-2016 IPR000014 PAS domain DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 PANTHER PTHR10799 435 559 2.7E-30 T 23-04-2016 DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 Gene3D G3DSA:3.30.70.270 431 558 2.0E-45 T 23-04-2016 DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 Gene3D G3DSA:3.30.70.270 338 361 2.0E-45 T 23-04-2016 DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 SUPERFAMILY SSF55781 12 192 3.93E-14 T 23-04-2016 IPR029016 GAF domain-like DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 Gene3D G3DSA:3.30.450.20 205 322 2.5E-19 T 23-04-2016 DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 SMART SM00086 283 325 1.4E-4 T 23-04-2016 IPR001610 PAC motif DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 SMART SM00065 29 195 0.0016 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 209 331 9.8E-16 T 23-04-2016 IPR000014 PAS domain DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 SUPERFAMILY SSF55073 433 558 1.15E-35 T 23-04-2016 IPR029787 Nucleotide cyclase DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 Gene3D G3DSA:3.30.450.40 10 200 3.1E-14 T 23-04-2016 IPR029016 GAF domain-like DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 Pfam PF08447 PAS fold 242 313 3.8E-7 T 23-04-2016 IPR013655 PAS fold-3 GO:0005515 DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 SUPERFAMILY SSF55785 201 321 1.1E-18 T 23-04-2016 IPR000014 PAS domain DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 433 558 5.9E-30 T 23-04-2016 IPR000160 GGDEF domain DC74_RS23470 f0b43dd0c43833faf3ec52eec1d5d0c5 563 SMART SM00267 325 562 6.5E-28 T 23-04-2016 IPR000160 GGDEF domain DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 Gene3D G3DSA:1.20.1560.10 13 327 4.1E-66 T 23-04-2016 DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 Gene3D G3DSA:1.20.1560.10 761 1074 2.0E-74 T 23-04-2016 DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 PANTHER PTHR24221 745 1275 2.7E-240 T 23-04-2016 DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 PANTHER PTHR24221 511 677 2.7E-240 T 23-04-2016 DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 PANTHER PTHR24221 1295 1353 2.7E-240 T 23-04-2016 DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 Gene3D G3DSA:3.40.50.300 391 606 5.2E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 Gene3D G3DSA:3.40.50.300 1089 1339 9.3E-76 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 SUPERFAMILY SSF52540 392 612 1.33E-80 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 SMART SM00382 1115 1320 4.6E-20 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 SMART SM00382 405 591 8.6E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 ProSitePatterns PS00211 ABC transporters family signature. 517 531 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 Pfam PF00664 ABC transporter transmembrane region 27 295 5.8E-34 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 Pfam PF00664 ABC transporter transmembrane region 773 1043 1.1E-39 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 Pfam PF00005 ABC transporter 1106 1255 6.1E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 Pfam PF00005 ABC transporter 396 545 1.3E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 SUPERFAMILY SSF52540 1079 1343 1.81E-80 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 SUPERFAMILY SSF90123 761 1070 2.75E-71 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS15810 fc0945ea2b2df97270eba234ba63aae8 1353 SUPERFAMILY SSF90123 13 327 2.62E-68 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS24100 4151d31916a97a8172ffb50fa0482fb2 280 SMART SM00530 23 81 1.7E-4 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS24100 4151d31916a97a8172ffb50fa0482fb2 280 SUPERFAMILY SSF47413 17 77 7.78E-8 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS24100 4151d31916a97a8172ffb50fa0482fb2 280 PANTHER PTHR10245 14 280 5.1E-41 T 23-04-2016 DC74_RS24100 4151d31916a97a8172ffb50fa0482fb2 280 Pfam PF13560 Helix-turn-helix domain 19 78 2.8E-8 T 23-04-2016 DC74_RS24100 4151d31916a97a8172ffb50fa0482fb2 280 Gene3D G3DSA:1.10.260.40 13 77 3.4E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS24100 4151d31916a97a8172ffb50fa0482fb2 280 PANTHER PTHR10245:SF7 14 280 5.1E-41 T 23-04-2016 DC74_RS01925 d3dcc29651af672ecd2320516995541b 405 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 50 61 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS01925 d3dcc29651af672ecd2320516995541b 405 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 16 27 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS01925 d3dcc29651af672ecd2320516995541b 405 SUPERFAMILY SSF54862 10 62 4.46E-9 T 23-04-2016 DC74_RS01925 d3dcc29651af672ecd2320516995541b 405 Gene3D G3DSA:3.30.70.20 12 62 8.5E-8 T 23-04-2016 DC74_RS01925 d3dcc29651af672ecd2320516995541b 405 Pfam PF13187 4Fe-4S dicluster domain 16 61 4.9E-8 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS01925 d3dcc29651af672ecd2320516995541b 405 PANTHER PTHR31332 6 349 2.4E-28 T 23-04-2016 DC74_RS01925 d3dcc29651af672ecd2320516995541b 405 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 179 349 6.6E-21 T 23-04-2016 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal DC74_RS01925 d3dcc29651af672ecd2320516995541b 405 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 92 169 1.2E-13 T 23-04-2016 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal DC74_RS02370 a2b06546e9d8517ebeef24820253b2e7 277 Gene3D G3DSA:3.30.450.40 86 252 5.5E-32 T 23-04-2016 IPR029016 GAF domain-like DC74_RS02370 a2b06546e9d8517ebeef24820253b2e7 277 Pfam PF01614 Bacterial transcriptional regulator 130 248 3.0E-14 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS02370 a2b06546e9d8517ebeef24820253b2e7 277 PANTHER PTHR30136 9 264 5.6E-58 T 23-04-2016 DC74_RS02370 a2b06546e9d8517ebeef24820253b2e7 277 Pfam PF09339 IclR helix-turn-helix domain 12 62 6.5E-12 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS02370 a2b06546e9d8517ebeef24820253b2e7 277 Gene3D G3DSA:1.10.10.10 7 78 5.2E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02370 a2b06546e9d8517ebeef24820253b2e7 277 PANTHER PTHR30136:SF14 9 264 5.6E-58 T 23-04-2016 DC74_RS02370 a2b06546e9d8517ebeef24820253b2e7 277 SUPERFAMILY SSF46785 10 81 6.43E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02370 a2b06546e9d8517ebeef24820253b2e7 277 SMART SM00346 9 99 1.8E-6 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS02370 a2b06546e9d8517ebeef24820253b2e7 277 SUPERFAMILY SSF55781 67 252 2.09E-31 T 23-04-2016 IPR029016 GAF domain-like DC74_RS27170 333318a46b7ce415dc33014b13a96f2d 257 Gene3D G3DSA:3.60.160.10 23 210 1.7E-20 T 23-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 DC74_RS27170 333318a46b7ce415dc33014b13a96f2d 257 Pfam PF01987 Mitochondrial biogenesis AIM24 29 209 2.3E-10 T 23-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 DC74_RS27170 333318a46b7ce415dc33014b13a96f2d 257 SUPERFAMILY SSF51219 22 210 1.52E-28 T 23-04-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain DC74_RS27170 333318a46b7ce415dc33014b13a96f2d 257 PANTHER PTHR38074:SF1 5 245 9.9E-68 T 23-04-2016 DC74_RS27170 333318a46b7ce415dc33014b13a96f2d 257 PANTHER PTHR38074 5 245 9.9E-68 T 23-04-2016 DC74_RS39135 367b38a45d3fca39cccf7ef8fe031cfc 219 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 22 209 4.4E-62 T 23-04-2016 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent DC74_RS39135 367b38a45d3fca39cccf7ef8fe031cfc 219 PANTHER PTHR30212 22 209 3.8E-30 T 23-04-2016 DC74_RS39135 367b38a45d3fca39cccf7ef8fe031cfc 219 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 43 136 1.5E-12 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS39135 367b38a45d3fca39cccf7ef8fe031cfc 219 PANTHER PTHR30212:SF4 22 209 3.8E-30 T 23-04-2016 DC74_RS39135 367b38a45d3fca39cccf7ef8fe031cfc 219 SUPERFAMILY SSF50475 43 163 5.33E-14 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS39135 367b38a45d3fca39cccf7ef8fe031cfc 219 Gene3D G3DSA:2.30.110.10 36 161 2.7E-26 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS12975 defd13777001d5812dead3b294974330 363 Gene3D G3DSA:3.40.50.150 10 204 6.5E-43 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS12975 defd13777001d5812dead3b294974330 363 PANTHER PTHR11579 58 198 5.9E-33 T 23-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 DC74_RS12975 defd13777001d5812dead3b294974330 363 PANTHER PTHR11579 1 41 5.9E-33 T 23-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 DC74_RS12975 defd13777001d5812dead3b294974330 363 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 157 172 - T 23-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 DC74_RS12975 defd13777001d5812dead3b294974330 363 SUPERFAMILY SSF53335 90 204 5.31E-25 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS12975 defd13777001d5812dead3b294974330 363 PANTHER PTHR11579:SF0 58 198 5.9E-33 T 23-04-2016 DC74_RS12975 defd13777001d5812dead3b294974330 363 PANTHER PTHR11579:SF0 1 41 5.9E-33 T 23-04-2016 DC74_RS12975 defd13777001d5812dead3b294974330 363 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 5 202 1.4E-25 T 23-04-2016 DC74_RS20615 f8666228e512af249b37f12016c07718 175 SUPERFAMILY SSF50891 6 171 3.51E-59 T 23-04-2016 IPR029000 Cyclophilin-like domain DC74_RS20615 f8666228e512af249b37f12016c07718 175 Gene3D G3DSA:2.40.100.10 4 172 1.0E-60 T 23-04-2016 IPR029000 Cyclophilin-like domain DC74_RS20615 f8666228e512af249b37f12016c07718 175 PIRSF PIRSF001467 1 175 1.7E-54 T 23-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 DC74_RS20615 f8666228e512af249b37f12016c07718 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 5.9E-27 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 DC74_RS20615 f8666228e512af249b37f12016c07718 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 61 73 5.9E-27 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 DC74_RS20615 f8666228e512af249b37f12016c07718 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 129 144 5.9E-27 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 DC74_RS20615 f8666228e512af249b37f12016c07718 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 101 116 5.9E-27 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 DC74_RS20615 f8666228e512af249b37f12016c07718 175 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 116 128 5.9E-27 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 DC74_RS20615 f8666228e512af249b37f12016c07718 175 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 170 2.0E-43 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 DC74_RS20615 f8666228e512af249b37f12016c07718 175 PANTHER PTHR11071 7 172 7.4E-69 T 23-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 DC74_RS20615 f8666228e512af249b37f12016c07718 175 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 56 73 - T 23-04-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 PANTHER PTHR24291:SF46 50 448 2.9E-82 T 23-04-2016 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 PANTHER PTHR24291 50 448 2.9E-82 T 23-04-2016 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 PRINTS PR00463 E-class P450 group I signature 279 305 6.4E-26 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 PRINTS PR00463 E-class P450 group I signature 259 276 6.4E-26 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 PRINTS PR00463 E-class P450 group I signature 396 406 6.4E-26 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 PRINTS PR00463 E-class P450 group I signature 46 65 6.4E-26 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 PRINTS PR00463 E-class P450 group I signature 406 429 6.4E-26 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 PRINTS PR00463 E-class P450 group I signature 361 385 6.4E-26 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 399 408 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 Pfam PF00067 Cytochrome P450 23 423 1.6E-69 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 Gene3D G3DSA:1.10.630.10 21 457 3.1E-102 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 SUPERFAMILY SSF48264 21 457 1.27E-98 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 PRINTS PR00385 P450 superfamily signature 270 287 2.5E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 PRINTS PR00385 P450 superfamily signature 322 333 2.5E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 PRINTS PR00385 P450 superfamily signature 397 406 2.5E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS36825 2fc383bdb01f5c9f4456029c65088544 459 PRINTS PR00385 P450 superfamily signature 406 417 2.5E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01400 a028d9bc3de74be8c0136d523e58d681 194 PANTHER PTHR10245:SF9 9 187 5.7E-35 T 23-04-2016 DC74_RS01400 a028d9bc3de74be8c0136d523e58d681 194 SUPERFAMILY SSF51182 54 183 1.08E-21 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS01400 a028d9bc3de74be8c0136d523e58d681 194 SUPERFAMILY SSF47413 9 74 6.76E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS01400 a028d9bc3de74be8c0136d523e58d681 194 Pfam PF13560 Helix-turn-helix domain 11 68 1.3E-10 T 23-04-2016 DC74_RS01400 a028d9bc3de74be8c0136d523e58d681 194 Pfam PF07883 Cupin domain 114 182 1.7E-12 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS01400 a028d9bc3de74be8c0136d523e58d681 194 PANTHER PTHR10245 9 187 5.7E-35 T 23-04-2016 DC74_RS01400 a028d9bc3de74be8c0136d523e58d681 194 Gene3D G3DSA:1.10.260.40 9 77 1.6E-17 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS01400 a028d9bc3de74be8c0136d523e58d681 194 SMART SM00530 14 69 2.0E-11 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS01400 a028d9bc3de74be8c0136d523e58d681 194 Gene3D G3DSA:2.60.120.10 97 188 4.8E-26 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 589 719 6.3E-16 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 PANTHER PTHR13779:SF20 526 806 3.1E-95 T 23-04-2016 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SUPERFAMILY SSF52540 547 758 3.69E-33 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00722 313 474 1.6E-8 T 23-04-2016 IPR006633 Carbohydrate-binding/sugar hydrolysis domain DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00722 41 172 2.8 T 23-04-2016 IPR006633 Carbohydrate-binding/sugar hydrolysis domain DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00382 584 723 1.5E-6 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SUPERFAMILY SSF51126 20 239 1.45E-27 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SUPERFAMILY SSF51126 353 450 1.71E-18 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SUPERFAMILY SSF51126 212 319 1.71E-18 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 PANTHER PTHR13779 526 806 3.1E-95 T 23-04-2016 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 Gene3D G3DSA:2.160.20.10 364 501 1.5E-11 T 23-04-2016 IPR012334 Pectin lyase fold DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 Gene3D G3DSA:2.160.20.10 5 285 5.1E-22 T 23-04-2016 IPR012334 Pectin lyase fold DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 Pfam PF13229 Right handed beta helix region 121 242 1.8E-14 T 23-04-2016 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 Pfam PF13229 Right handed beta helix region 385 491 5.3E-11 T 23-04-2016 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 PRINTS PR00819 CbxX/CfqX superfamily signature 587 602 2.625292E-48 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 PRINTS PR00819 CbxX/CfqX superfamily signature 625 639 2.625292E-48 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 PRINTS PR00819 CbxX/CfqX superfamily signature 639 658 2.625292E-48 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 PRINTS PR00819 CbxX/CfqX superfamily signature 765 777 2.625292E-48 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 PRINTS PR00819 CbxX/CfqX superfamily signature 708 727 2.625292E-48 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 PRINTS PR00819 CbxX/CfqX superfamily signature 670 682 2.625292E-48 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 PRINTS PR00819 CbxX/CfqX superfamily signature 691 708 2.625292E-48 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 PRINTS PR00819 CbxX/CfqX superfamily signature 547 561 2.625292E-48 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00710 407 429 34.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00710 244 266 6100.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00710 339 361 5700.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00710 362 383 2200.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00710 267 289 1300.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00710 221 243 680.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00710 430 452 630.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00710 128 150 9.4 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00710 174 196 9.6 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00710 453 475 5200.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00710 385 406 61.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 SMART SM00710 151 173 880.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08755 e3ba2fac37d9adfeced7b3a7c902719d 807 Gene3D G3DSA:3.40.50.300 548 733 3.7E-25 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 SMART SM00421 158 215 1.4E-26 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 SMART SM00448 7 119 6.8E-34 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 1.4E-20 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 Pfam PF00072 Response regulator receiver domain 9 120 7.4E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 Gene3D G3DSA:3.40.50.2300 6 159 5.1E-35 T 23-04-2016 DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 7.2E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 7.2E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 7.2E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 PANTHER PTHR26402:SF151 7 220 2.7E-69 T 23-04-2016 DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 Gene3D G3DSA:1.10.10.10 160 220 4.4E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 SUPERFAMILY SSF52172 5 174 8.75E-33 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 SUPERFAMILY SSF46894 159 220 2.34E-20 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS12735 b6baf615676b1ef20862465a21bb3559 223 PANTHER PTHR26402 7 220 2.7E-69 T 23-04-2016 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 Pfam PF02803 Thiolase, C-terminal domain 275 374 2.2E-11 T 23-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 SUPERFAMILY SSF53901 5 239 3.84E-48 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 Gene3D G3DSA:3.40.47.10 22 118 8.1E-30 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 Gene3D G3DSA:3.40.47.10 210 230 8.1E-30 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 PIRSF PIRSF000429 1 396 9.3E-70 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 79 97 - T 23-04-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 23-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 PANTHER PTHR18919:SF83 1 397 4.3E-189 T 23-04-2016 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 PANTHER PTHR18919 1 397 4.3E-189 T 23-04-2016 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 SUPERFAMILY SSF53901 263 386 6.92E-32 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 Pfam PF00108 Thiolase, N-terminal domain 6 231 1.6E-20 T 23-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 Gene3D G3DSA:3.40.47.10 151 191 5.5E-28 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS13595 d9e1a30fdeea3ca27776ae5941db206a 397 Gene3D G3DSA:3.40.47.10 257 393 5.5E-28 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS14830 871adcfa30291c6e73ccbc29379fd675 334 PANTHER PTHR11732:SF12 1 333 3.7E-112 T 23-04-2016 DC74_RS14830 871adcfa30291c6e73ccbc29379fd675 334 Gene3D G3DSA:3.20.20.100 2 325 2.3E-93 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS14830 871adcfa30291c6e73ccbc29379fd675 334 Pfam PF00248 Aldo/keto reductase family 16 311 1.8E-63 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS14830 871adcfa30291c6e73ccbc29379fd675 334 SUPERFAMILY SSF51430 2 314 4.71E-87 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS14830 871adcfa30291c6e73ccbc29379fd675 334 PANTHER PTHR11732 1 333 3.7E-112 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS12840 b3d82f21a7e6c03f597d08dbd22d9310 566 Pfam PF13408 Recombinase zinc beta ribbon domain 342 390 9.6E-6 T 23-04-2016 IPR025827 Recombinase zinc beta ribbon domain DC74_RS12840 b3d82f21a7e6c03f597d08dbd22d9310 566 PANTHER PTHR30461 12 232 7.7E-30 T 23-04-2016 DC74_RS12840 b3d82f21a7e6c03f597d08dbd22d9310 566 PANTHER PTHR30461 255 499 7.7E-30 T 23-04-2016 DC74_RS12840 b3d82f21a7e6c03f597d08dbd22d9310 566 PANTHER PTHR30461:SF2 12 232 7.7E-30 T 23-04-2016 DC74_RS12840 b3d82f21a7e6c03f597d08dbd22d9310 566 PANTHER PTHR30461:SF2 255 499 7.7E-30 T 23-04-2016 DC74_RS12840 b3d82f21a7e6c03f597d08dbd22d9310 566 Pfam PF00239 Resolvase, N terminal domain 12 165 5.2E-14 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS12840 b3d82f21a7e6c03f597d08dbd22d9310 566 Gene3D G3DSA:3.40.50.1390 17 151 1.1E-9 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS12840 b3d82f21a7e6c03f597d08dbd22d9310 566 SUPERFAMILY SSF53041 15 165 1.57E-12 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS12840 b3d82f21a7e6c03f597d08dbd22d9310 566 Pfam PF07508 Recombinase 200 321 8.0E-16 T 23-04-2016 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 DC74_RS12840 b3d82f21a7e6c03f597d08dbd22d9310 566 SMART SM00857 8 169 7.4E-6 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS04960 c18ae5d1178bdd44ca12ec8b8de3b9a2 627 SUPERFAMILY SSF51556 76 138 4.16E-36 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS04960 c18ae5d1178bdd44ca12ec8b8de3b9a2 627 SUPERFAMILY SSF51556 218 508 4.16E-36 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS04960 c18ae5d1178bdd44ca12ec8b8de3b9a2 627 Gene3D G3DSA:2.30.40.10 492 528 2.8E-5 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS04960 c18ae5d1178bdd44ca12ec8b8de3b9a2 627 PANTHER PTHR22642 1 567 1.5E-139 T 23-04-2016 DC74_RS04960 c18ae5d1178bdd44ca12ec8b8de3b9a2 627 Gene3D G3DSA:2.30.40.10 12 109 3.4E-15 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS04960 c18ae5d1178bdd44ca12ec8b8de3b9a2 627 SUPERFAMILY SSF51338 14 77 2.55E-21 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS04960 c18ae5d1178bdd44ca12ec8b8de3b9a2 627 SUPERFAMILY SSF51338 508 558 2.55E-21 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS04960 c18ae5d1178bdd44ca12ec8b8de3b9a2 627 Pfam PF07969 Amidohydrolase family 65 549 2.7E-105 T 23-04-2016 IPR013108 Amidohydrolase 3 DC74_RS04960 c18ae5d1178bdd44ca12ec8b8de3b9a2 627 PANTHER PTHR22642:SF2 1 567 1.5E-139 T 23-04-2016 DC74_RS04960 c18ae5d1178bdd44ca12ec8b8de3b9a2 627 Gene3D G3DSA:3.20.20.140 220 491 1.6E-18 T 23-04-2016 DC74_RS10435 5b5065985b6fb00dc8217403967946a4 570 SUPERFAMILY SSF52540 297 501 1.2E-34 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10435 5b5065985b6fb00dc8217403967946a4 570 SUPERFAMILY SSF52540 2 223 1.31E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10435 5b5065985b6fb00dc8217403967946a4 570 Gene3D G3DSA:3.40.50.300 2 226 7.2E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10435 5b5065985b6fb00dc8217403967946a4 570 SMART SM00382 25 211 2.3E-5 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS10435 5b5065985b6fb00dc8217403967946a4 570 Pfam PF00005 ABC transporter 300 447 1.2E-16 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS10435 5b5065985b6fb00dc8217403967946a4 570 Pfam PF00005 ABC transporter 16 164 1.8E-24 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS10435 5b5065985b6fb00dc8217403967946a4 570 PANTHER PTHR24220:SF308 264 406 2.1E-109 T 23-04-2016 DC74_RS10435 5b5065985b6fb00dc8217403967946a4 570 PANTHER PTHR24220:SF308 2 238 2.1E-109 T 23-04-2016 DC74_RS10435 5b5065985b6fb00dc8217403967946a4 570 PANTHER PTHR24220 264 406 2.1E-109 T 23-04-2016 DC74_RS10435 5b5065985b6fb00dc8217403967946a4 570 PANTHER PTHR24220 2 238 2.1E-109 T 23-04-2016 DC74_RS10435 5b5065985b6fb00dc8217403967946a4 570 Gene3D G3DSA:3.40.50.300 300 500 8.5E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10435 5b5065985b6fb00dc8217403967946a4 570 ProSitePatterns PS00211 ABC transporters family signature. 424 438 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS38990 0f6b5b204bb04036bc7f265e44baa7ba 231 Pfam PF00535 Glycosyl transferase family 2 3 151 1.4E-20 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS38990 0f6b5b204bb04036bc7f265e44baa7ba 231 PANTHER PTHR10859 1 216 6.7E-55 T 23-04-2016 DC74_RS38990 0f6b5b204bb04036bc7f265e44baa7ba 231 Gene3D G3DSA:3.90.550.10 2 195 1.3E-18 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS38990 0f6b5b204bb04036bc7f265e44baa7ba 231 SUPERFAMILY SSF53448 1 209 8.19E-38 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS38990 0f6b5b204bb04036bc7f265e44baa7ba 231 PANTHER PTHR10859:SF95 1 216 6.7E-55 T 23-04-2016 DC74_RS18390 242e9f6339ca9c4282dc064bec9053ac 319 SUPERFAMILY SSF47203 187 317 3.54E-29 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS18390 242e9f6339ca9c4282dc064bec9053ac 319 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 189 306 1.6E-19 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS18390 242e9f6339ca9c4282dc064bec9053ac 319 Gene3D G3DSA:1.10.540.10 2 91 4.4E-14 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS18390 242e9f6339ca9c4282dc064bec9053ac 319 SUPERFAMILY SSF56645 2 107 9.95E-16 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS18390 242e9f6339ca9c4282dc064bec9053ac 319 PANTHER PTHR10909:SF302 1 318 6.8E-39 T 23-04-2016 DC74_RS18390 242e9f6339ca9c4282dc064bec9053ac 319 PANTHER PTHR10909 1 318 6.8E-39 T 23-04-2016 DC74_RS18390 242e9f6339ca9c4282dc064bec9053ac 319 Gene3D G3DSA:1.20.140.10 187 304 5.4E-26 T 23-04-2016 DC74_RS18390 242e9f6339ca9c4282dc064bec9053ac 319 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 91 2.3E-11 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 PANTHER PTHR30204:SF22 1 213 6.9E-31 T 23-04-2016 DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 PANTHER PTHR30204:SF22 231 290 6.9E-31 T 23-04-2016 DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 SMART SM00422 2 72 1.0E-19 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 Gene3D G3DSA:3.20.80.10 230 287 1.4E-5 T 23-04-2016 IPR011256 Regulatory factor, effector binding domain DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 Gene3D G3DSA:1.10.1660.10 1 57 2.2E-21 T 23-04-2016 DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 Gene3D G3DSA:1.10.1660.10 58 116 7.2E-6 T 23-04-2016 DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 SMART SM00871 119 288 2.0E-8 T 23-04-2016 IPR010499 Bacterial transcription activator, effector binding DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 Pfam PF13411 MerR HTH family regulatory protein 2 71 2.8E-14 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 Pfam PF06445 GyrI-like small molecule binding domain 148 287 1.0E-7 T 23-04-2016 IPR029442 GyrI-like small molecule binding domain DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 SUPERFAMILY SSF55136 120 288 4.71E-14 T 23-04-2016 IPR011256 Regulatory factor, effector binding domain DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 SUPERFAMILY SSF46955 2 116 1.39E-23 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 PANTHER PTHR30204 1 213 6.9E-31 T 23-04-2016 DC74_RS21140 44dd9e2eb6b1eadd3d95af140913a3cb 290 PANTHER PTHR30204 231 290 6.9E-31 T 23-04-2016 DC74_RS12630 a30d2f5b277f38c554ae7443afbca7f0 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 5.0E-18 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS12630 a30d2f5b277f38c554ae7443afbca7f0 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.6E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS12630 a30d2f5b277f38c554ae7443afbca7f0 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.6E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS12630 a30d2f5b277f38c554ae7443afbca7f0 204 Gene3D G3DSA:1.10.357.10 64 197 6.5E-29 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS12630 a30d2f5b277f38c554ae7443afbca7f0 204 Gene3D G3DSA:1.10.10.60 44 63 5.5E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS12630 a30d2f5b277f38c554ae7443afbca7f0 204 Gene3D G3DSA:1.10.10.60 6 43 2.1E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS12630 a30d2f5b277f38c554ae7443afbca7f0 204 PANTHER PTHR30328 7 202 3.1E-56 T 23-04-2016 DC74_RS12630 a30d2f5b277f38c554ae7443afbca7f0 204 SUPERFAMILY SSF46689 5 82 5.13E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS12630 a30d2f5b277f38c554ae7443afbca7f0 204 PANTHER PTHR30328:SF24 7 202 3.1E-56 T 23-04-2016 DC74_RS12630 a30d2f5b277f38c554ae7443afbca7f0 204 SUPERFAMILY SSF48498 88 195 1.2E-16 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS33280 0e87f6e1cf52d2a8a7e9f42e3d2a3c08 313 SUPERFAMILY SSF102114 13 240 6.8E-16 T 23-04-2016 DC74_RS33280 0e87f6e1cf52d2a8a7e9f42e3d2a3c08 313 Gene3D G3DSA:3.20.20.70 13 241 4.4E-9 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS02910 c54f23ad5a0d7afe4c1a318b5a82f823 236 SUPERFAMILY SSF101898 2 80 2.88E-12 T 23-04-2016 DC74_RS02910 c54f23ad5a0d7afe4c1a318b5a82f823 236 Pfam PF01436 NHL repeat 49 75 3.2E-8 T 23-04-2016 IPR001258 NHL repeat GO:0005515 DC74_RS02910 c54f23ad5a0d7afe4c1a318b5a82f823 236 Gene3D G3DSA:2.120.10.30 1 78 5.0E-20 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS02910 c54f23ad5a0d7afe4c1a318b5a82f823 236 SUPERFAMILY SSF50370 87 234 1.36E-19 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS02910 c54f23ad5a0d7afe4c1a318b5a82f823 236 Gene3D G3DSA:2.80.10.50 101 234 4.1E-14 T 23-04-2016 DC74_RS02910 c54f23ad5a0d7afe4c1a318b5a82f823 236 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 125 219 7.9E-15 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS20610 9719344b6bf863085ea275f86c9f155f 304 Gene3D G3DSA:1.20.1540.10 88 268 7.8E-41 T 23-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 DC74_RS20610 9719344b6bf863085ea275f86c9f155f 304 Pfam PF00643 B-box zinc finger 22 48 2.0E-5 T 23-04-2016 IPR000315 B-box-type zinc finger GO:0005622|GO:0008270 DC74_RS20610 9719344b6bf863085ea275f86c9f155f 304 SUPERFAMILY SSF144091 86 275 1.07E-43 T 23-04-2016 DC74_RS20610 9719344b6bf863085ea275f86c9f155f 304 Pfam PF01694 Rhomboid family 136 270 4.4E-38 T 23-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 DC74_RS20610 9719344b6bf863085ea275f86c9f155f 304 PANTHER PTHR22936 88 295 1.9E-47 T 23-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 DC74_RS27295 29bce5353eb0418c3c6f1188eca72c4a 236 SMART SM00530 86 142 6.8E-4 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS27295 29bce5353eb0418c3c6f1188eca72c4a 236 SMART SM00530 19 80 0.15 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS27295 29bce5353eb0418c3c6f1188eca72c4a 236 Gene3D G3DSA:1.10.260.40 21 82 3.4E-8 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS27295 29bce5353eb0418c3c6f1188eca72c4a 236 Gene3D G3DSA:1.10.260.40 87 147 2.3E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS27295 29bce5353eb0418c3c6f1188eca72c4a 236 SUPERFAMILY SSF47413 86 148 8.44E-6 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS09520 a06c78046bb86d5c0270d8920d8c2ccf 154 Gene3D G3DSA:3.30.420.140 3 144 2.4E-46 T 23-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 DC74_RS09520 a06c78046bb86d5c0270d8920d8c2ccf 154 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 140 22.06 T 23-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 DC74_RS09520 a06c78046bb86d5c0270d8920d8c2ccf 154 Pfam PF03652 Holliday junction resolvase 5 137 5.0E-42 T 23-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 DC74_RS09520 a06c78046bb86d5c0270d8920d8c2ccf 154 PANTHER PTHR33317:SF1 1 154 9.2E-42 T 23-04-2016 DC74_RS09520 a06c78046bb86d5c0270d8920d8c2ccf 154 SUPERFAMILY SSF53098 4 137 2.73E-34 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS09520 a06c78046bb86d5c0270d8920d8c2ccf 154 SMART SM00732 4 105 1.3E-30 T 23-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 DC74_RS09520 a06c78046bb86d5c0270d8920d8c2ccf 154 PANTHER PTHR33317 1 154 9.2E-42 T 23-04-2016 DC74_RS09520 a06c78046bb86d5c0270d8920d8c2ccf 154 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 8 137 5.7E-30 T 23-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 DC74_RS32895 0eda3223117d557d1ba8f27848a65158 234 Gene3D G3DSA:1.10.10.10 144 232 4.9E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32895 0eda3223117d557d1ba8f27848a65158 234 SUPERFAMILY SSF46894 138 231 2.07E-26 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS32895 0eda3223117d557d1ba8f27848a65158 234 Pfam PF00072 Response regulator receiver domain 4 112 2.6E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS32895 0eda3223117d557d1ba8f27848a65158 234 PANTHER PTHR26402:SF50 2 233 1.2E-88 T 23-04-2016 DC74_RS32895 0eda3223117d557d1ba8f27848a65158 234 Gene3D G3DSA:3.40.50.2300 1 143 1.1E-40 T 23-04-2016 DC74_RS32895 0eda3223117d557d1ba8f27848a65158 234 SMART SM00448 2 112 2.9E-43 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS32895 0eda3223117d557d1ba8f27848a65158 234 SUPERFAMILY SSF52172 1 122 7.12E-42 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS32895 0eda3223117d557d1ba8f27848a65158 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 231 6.0E-26 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS32895 0eda3223117d557d1ba8f27848a65158 234 SMART SM00862 155 231 4.2E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS32895 0eda3223117d557d1ba8f27848a65158 234 PANTHER PTHR26402 2 233 1.2E-88 T 23-04-2016 DC74_RS37575 2856c7f36cc4c5759c93caca22e29362 312 Pfam PF03466 LysR substrate binding domain 89 293 6.5E-41 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS37575 2856c7f36cc4c5759c93caca22e29362 312 Gene3D G3DSA:1.10.10.10 6 88 1.1E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37575 2856c7f36cc4c5759c93caca22e29362 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.5E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS37575 2856c7f36cc4c5759c93caca22e29362 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.5E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS37575 2856c7f36cc4c5759c93caca22e29362 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.5E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS37575 2856c7f36cc4c5759c93caca22e29362 312 SUPERFAMILY SSF53850 90 294 4.35E-36 T 23-04-2016 DC74_RS37575 2856c7f36cc4c5759c93caca22e29362 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.9E-17 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS37575 2856c7f36cc4c5759c93caca22e29362 312 Gene3D G3DSA:3.40.190.10 179 268 8.9E-24 T 23-04-2016 DC74_RS37575 2856c7f36cc4c5759c93caca22e29362 312 Gene3D G3DSA:3.40.190.10 90 178 8.0E-26 T 23-04-2016 DC74_RS37575 2856c7f36cc4c5759c93caca22e29362 312 SUPERFAMILY SSF46785 5 88 1.14E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37575 2856c7f36cc4c5759c93caca22e29362 312 PANTHER PTHR30346 1 312 1.0E-78 T 23-04-2016 DC74_RS24075 8d8d5de1350a5481cc089c26068d2b07 282 SUPERFAMILY SSF47413 14 68 2.03E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS24075 8d8d5de1350a5481cc089c26068d2b07 282 SMART SM00530 19 74 1.2E-5 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS24075 8d8d5de1350a5481cc089c26068d2b07 282 PANTHER PTHR10245 10 282 3.1E-44 T 23-04-2016 DC74_RS24075 8d8d5de1350a5481cc089c26068d2b07 282 PANTHER PTHR10245:SF7 10 282 3.1E-44 T 23-04-2016 DC74_RS24075 8d8d5de1350a5481cc089c26068d2b07 282 Pfam PF13560 Helix-turn-helix domain 17 71 2.1E-11 T 23-04-2016 DC74_RS24075 8d8d5de1350a5481cc089c26068d2b07 282 Gene3D G3DSA:1.10.260.40 7 69 6.5E-15 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS25650 5c589a60de7d6dae7aa3786b8385628e 306 Pfam PF00480 ROK family 4 164 1.4E-16 T 23-04-2016 IPR000600 ROK family DC74_RS25650 5c589a60de7d6dae7aa3786b8385628e 306 Gene3D G3DSA:3.30.420.40 1 109 4.0E-40 T 23-04-2016 DC74_RS25650 5c589a60de7d6dae7aa3786b8385628e 306 Gene3D G3DSA:3.30.420.40 110 248 3.6E-39 T 23-04-2016 DC74_RS25650 5c589a60de7d6dae7aa3786b8385628e 306 PANTHER PTHR18964 1 247 4.7E-79 T 23-04-2016 DC74_RS25650 5c589a60de7d6dae7aa3786b8385628e 306 PANTHER PTHR18964:SF138 1 247 4.7E-79 T 23-04-2016 DC74_RS25650 5c589a60de7d6dae7aa3786b8385628e 306 SUPERFAMILY SSF53067 1 249 2.41E-37 T 23-04-2016 DC74_RS03215 08a4a167f8656389c951d05af3961c70 537 SUPERFAMILY SSF52467 158 330 4.41E-38 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS03215 08a4a167f8656389c951d05af3961c70 537 SUPERFAMILY SSF52518 2 180 3.84E-47 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS03215 08a4a167f8656389c951d05af3961c70 537 Gene3D G3DSA:3.40.50.970 2 182 2.8E-52 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS03215 08a4a167f8656389c951d05af3961c70 537 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 320 4.8E-27 T 23-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DC74_RS03215 08a4a167f8656389c951d05af3961c70 537 PANTHER PTHR18968 3 529 3.2E-136 T 23-04-2016 DC74_RS03215 08a4a167f8656389c951d05af3961c70 537 SUPERFAMILY SSF52518 367 532 6.43E-56 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS03215 08a4a167f8656389c951d05af3961c70 537 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 171 6.5E-47 T 23-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DC74_RS03215 08a4a167f8656389c951d05af3961c70 537 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 422 441 - T 23-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 DC74_RS03215 08a4a167f8656389c951d05af3961c70 537 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 531 1.4E-39 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS03215 08a4a167f8656389c951d05af3961c70 537 Gene3D G3DSA:3.40.50.1220 188 379 1.2E-40 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS03215 08a4a167f8656389c951d05af3961c70 537 Gene3D G3DSA:3.40.50.970 380 532 8.5E-56 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS00380 3dd37418d5fcefeb0ce7536f43788a7d 188 PANTHER PTHR38011:SF2 2 188 1.1E-25 T 23-04-2016 DC74_RS00380 3dd37418d5fcefeb0ce7536f43788a7d 188 Gene3D G3DSA:3.40.430.10 3 187 1.4E-30 T 23-04-2016 IPR024072 Dihydrofolate reductase-like domain DC74_RS00380 3dd37418d5fcefeb0ce7536f43788a7d 188 SUPERFAMILY SSF53597 2 186 9.16E-34 T 23-04-2016 IPR024072 Dihydrofolate reductase-like domain DC74_RS00380 3dd37418d5fcefeb0ce7536f43788a7d 188 Pfam PF01872 RibD C-terminal domain 2 181 3.1E-23 T 23-04-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 DC74_RS00380 3dd37418d5fcefeb0ce7536f43788a7d 188 PANTHER PTHR38011 2 188 1.1E-25 T 23-04-2016 DC74_RS07475 567ea19229697cf8f786199fd788e8cd 110 Pfam PF04673 Polyketide synthesis cyclase 2 105 4.4E-45 T 23-04-2016 IPR006765 Polyketide synthesis cyclase GO:0030639 DC74_RS07475 567ea19229697cf8f786199fd788e8cd 110 Gene3D G3DSA:3.30.70.1090 1 107 1.9E-46 T 23-04-2016 IPR006765 Polyketide synthesis cyclase GO:0030639 DC74_RS07475 567ea19229697cf8f786199fd788e8cd 110 SUPERFAMILY SSF54909 1 106 7.51E-42 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS07475 567ea19229697cf8f786199fd788e8cd 110 ProDom PD012644 CYCLASE POLYKETIDE II SYNTHESIS ORF SYNTHASE JADI BIOSYNTHESIS ANTIBIOTIC CYCLASE-LIKE 2 105 5.0E-42 T 23-04-2016 IPR006765 Polyketide synthesis cyclase GO:0030639 DC74_RS05100 6699d381ff7c83fbf00e65f5bc69d405 156 PANTHER PTHR24322 62 94 1.4E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05100 6699d381ff7c83fbf00e65f5bc69d405 156 PANTHER PTHR24322 1 45 1.4E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05100 6699d381ff7c83fbf00e65f5bc69d405 156 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 49 77 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS05100 6699d381ff7c83fbf00e65f5bc69d405 156 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 4 152 1.3E-36 T 23-04-2016 DC74_RS05100 6699d381ff7c83fbf00e65f5bc69d405 156 SUPERFAMILY SSF51735 3 152 2.45E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05100 6699d381ff7c83fbf00e65f5bc69d405 156 Gene3D G3DSA:3.40.50.720 3 152 1.9E-51 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05100 6699d381ff7c83fbf00e65f5bc69d405 156 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 136 1.1E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05100 6699d381ff7c83fbf00e65f5bc69d405 156 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 62 81 1.1E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05100 6699d381ff7c83fbf00e65f5bc69d405 156 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 100 1.1E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05100 6699d381ff7c83fbf00e65f5bc69d405 156 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 35 51 1.1E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05100 6699d381ff7c83fbf00e65f5bc69d405 156 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 41 49 3.1E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05100 6699d381ff7c83fbf00e65f5bc69d405 156 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 62 81 3.1E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18990 6be12f7164b4f61c552f7b29dd526521 337 PANTHER PTHR12001:SF47 20 337 5.1E-95 T 23-04-2016 DC74_RS18990 6be12f7164b4f61c552f7b29dd526521 337 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 212 224 - T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 DC74_RS18990 6be12f7164b4f61c552f7b29dd526521 337 Pfam PF00348 Polyprenyl synthetase 42 257 3.5E-57 T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 DC74_RS18990 6be12f7164b4f61c552f7b29dd526521 337 SUPERFAMILY SSF48576 20 335 2.59E-80 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS18990 6be12f7164b4f61c552f7b29dd526521 337 PANTHER PTHR12001 20 337 5.1E-95 T 23-04-2016 IPR017446 Polyprenyl synthetase-related DC74_RS18990 6be12f7164b4f61c552f7b29dd526521 337 Gene3D G3DSA:1.10.600.10 16 335 5.4E-86 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS07405 14af676e46521e0f8b125d2b90bc26a5 679 Pfam PF00931 NB-ARC domain 22 219 2.6E-11 T 23-04-2016 IPR002182 NB-ARC GO:0043531 DC74_RS07405 14af676e46521e0f8b125d2b90bc26a5 679 PRINTS PR00364 Disease resistance protein signature 100 114 2.6E-8 T 23-04-2016 DC74_RS07405 14af676e46521e0f8b125d2b90bc26a5 679 PRINTS PR00364 Disease resistance protein signature 31 46 2.6E-8 T 23-04-2016 DC74_RS07405 14af676e46521e0f8b125d2b90bc26a5 679 PRINTS PR00364 Disease resistance protein signature 198 212 2.6E-8 T 23-04-2016 DC74_RS07405 14af676e46521e0f8b125d2b90bc26a5 679 Gene3D G3DSA:1.25.40.10 404 497 1.6E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS07405 14af676e46521e0f8b125d2b90bc26a5 679 Gene3D G3DSA:3.40.50.300 13 141 7.5E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07405 14af676e46521e0f8b125d2b90bc26a5 679 SUPERFAMILY SSF52540 6 228 2.49E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07405 14af676e46521e0f8b125d2b90bc26a5 679 SUPERFAMILY SSF48452 395 532 4.17E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS24925 cf6978f23d9dac1c563275c75c860f56 536 Pfam PF00005 ABC transporter 33 178 4.4E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS24925 cf6978f23d9dac1c563275c75c860f56 536 Pfam PF00005 ABC transporter 286 442 1.7E-15 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS24925 cf6978f23d9dac1c563275c75c860f56 536 ProSitePatterns PS00211 ABC transporters family signature. 415 429 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS24925 cf6978f23d9dac1c563275c75c860f56 536 PANTHER PTHR24220 18 395 2.0E-180 T 23-04-2016 DC74_RS24925 cf6978f23d9dac1c563275c75c860f56 536 SUPERFAMILY SSF52540 15 234 3.47E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24925 cf6978f23d9dac1c563275c75c860f56 536 PANTHER PTHR24220:SF239 18 395 2.0E-180 T 23-04-2016 DC74_RS24925 cf6978f23d9dac1c563275c75c860f56 536 SMART SM00382 41 226 7.8E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS24925 cf6978f23d9dac1c563275c75c860f56 536 Gene3D G3DSA:3.40.50.300 14 236 2.2E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24925 cf6978f23d9dac1c563275c75c860f56 536 Gene3D G3DSA:3.40.50.300 262 505 2.7E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24925 cf6978f23d9dac1c563275c75c860f56 536 SUPERFAMILY SSF52540 261 499 5.99E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15600 95fce11ef1628db66d27f66253df403c 181 PIRSF PIRSF002070 2 160 3.4E-19 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 DC74_RS15600 95fce11ef1628db66d27f66253df403c 181 Pfam PF00436 Single-strand binding protein family 6 90 1.2E-18 T 23-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 DC74_RS15600 95fce11ef1628db66d27f66253df403c 181 Gene3D G3DSA:2.40.50.140 4 120 3.2E-28 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS15600 95fce11ef1628db66d27f66253df403c 181 SUPERFAMILY SSF50249 5 122 2.88E-23 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS15600 95fce11ef1628db66d27f66253df403c 181 PANTHER PTHR10302 5 92 1.2E-12 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 DC74_RS00580 b062aaa224ef21f3949fbfbda6b5cc4e 134 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 8 114 7.9E-38 T 23-04-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- DC74_RS00580 b062aaa224ef21f3949fbfbda6b5cc4e 134 PANTHER PTHR13774:SF18 1 125 2.6E-58 T 23-04-2016 DC74_RS00580 b062aaa224ef21f3949fbfbda6b5cc4e 134 PANTHER PTHR13774 1 125 2.6E-58 T 23-04-2016 DC74_RS00580 b062aaa224ef21f3949fbfbda6b5cc4e 134 Pfam PF02567 Phenazine biosynthesis-like protein 12 115 1.4E-36 T 23-04-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- DC74_RS00580 b062aaa224ef21f3949fbfbda6b5cc4e 134 SUPERFAMILY SSF54506 7 128 4.97E-43 T 23-04-2016 DC74_RS00580 b062aaa224ef21f3949fbfbda6b5cc4e 134 Gene3D G3DSA:3.10.310.10 6 126 3.2E-44 T 23-04-2016 DC74_RS27560 fb6a61c29b2ac5e3f79d7953c5698a62 229 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 201 0.0027 T 23-04-2016 DC74_RS27560 fb6a61c29b2ac5e3f79d7953c5698a62 229 PANTHER PTHR24322 6 180 5.6E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS27560 fb6a61c29b2ac5e3f79d7953c5698a62 229 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS27560 fb6a61c29b2ac5e3f79d7953c5698a62 229 Pfam PF00106 short chain dehydrogenase 5 188 7.3E-37 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS27560 fb6a61c29b2ac5e3f79d7953c5698a62 229 PANTHER PTHR24322:SF330 6 180 5.6E-38 T 23-04-2016 DC74_RS27560 fb6a61c29b2ac5e3f79d7953c5698a62 229 Gene3D G3DSA:3.40.50.720 5 216 3.7E-47 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27560 fb6a61c29b2ac5e3f79d7953c5698a62 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 8.6E-19 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS27560 fb6a61c29b2ac5e3f79d7953c5698a62 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 8.6E-19 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS27560 fb6a61c29b2ac5e3f79d7953c5698a62 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 8.6E-19 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS27560 fb6a61c29b2ac5e3f79d7953c5698a62 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 8.6E-19 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS27560 fb6a61c29b2ac5e3f79d7953c5698a62 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 8.6E-19 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS27560 fb6a61c29b2ac5e3f79d7953c5698a62 229 SUPERFAMILY SSF51735 3 216 6.5E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07715 347a547fec7209d0f198eda11bdf56ae 410 PANTHER PTHR23505 1 380 1.3E-48 T 23-04-2016 DC74_RS07715 347a547fec7209d0f198eda11bdf56ae 410 Pfam PF07690 Major Facilitator Superfamily 12 349 4.5E-25 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS07715 347a547fec7209d0f198eda11bdf56ae 410 Gene3D G3DSA:1.20.1250.20 210 388 3.0E-22 T 23-04-2016 DC74_RS07715 347a547fec7209d0f198eda11bdf56ae 410 Gene3D G3DSA:1.20.1250.20 3 173 4.3E-19 T 23-04-2016 DC74_RS07715 347a547fec7209d0f198eda11bdf56ae 410 PANTHER PTHR23505:SF8 1 380 1.3E-48 T 23-04-2016 DC74_RS07715 347a547fec7209d0f198eda11bdf56ae 410 SUPERFAMILY SSF103473 6 387 1.15E-46 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS29305 0a99942160a2391c3e8d22bcc7182c23 129 Hamap MF_01197 Cell division protein SepF [sepF]. 11 126 13.992 T 23-04-2016 IPR023052 Cell division protein SepF GO:0090529 DC74_RS29305 0a99942160a2391c3e8d22bcc7182c23 129 PANTHER PTHR35798 1 118 1.0E-28 T 23-04-2016 DC74_RS29305 0a99942160a2391c3e8d22bcc7182c23 129 Pfam PF04472 Protein of unknown function (DUF552) 48 118 1.2E-20 T 23-04-2016 IPR007561 Cell division protein SepF/SepF-related GO:0000917 DC74_RS29305 0a99942160a2391c3e8d22bcc7182c23 129 PANTHER PTHR35798:SF1 1 118 1.0E-28 T 23-04-2016 DC74_RS05225 332c463e8188801cfadbb6cbb398d054 509 Pfam PF00005 ABC transporter 18 164 1.8E-17 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS05225 332c463e8188801cfadbb6cbb398d054 509 Pfam PF00005 ABC transporter 279 427 3.0E-24 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS05225 332c463e8188801cfadbb6cbb398d054 509 SUPERFAMILY SSF52540 3 237 1.65E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05225 332c463e8188801cfadbb6cbb398d054 509 PANTHER PTHR24220:SF574 3 344 2.8E-82 T 23-04-2016 DC74_RS05225 332c463e8188801cfadbb6cbb398d054 509 SUPERFAMILY SSF52540 245 503 3.03E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05225 332c463e8188801cfadbb6cbb398d054 509 SMART SM00382 26 213 9.5E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS05225 332c463e8188801cfadbb6cbb398d054 509 SMART SM00382 284 475 6.5E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS05225 332c463e8188801cfadbb6cbb398d054 509 Gene3D G3DSA:3.40.50.300 249 505 8.7E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05225 332c463e8188801cfadbb6cbb398d054 509 Gene3D G3DSA:3.40.50.300 3 239 2.6E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05225 332c463e8188801cfadbb6cbb398d054 509 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS05225 332c463e8188801cfadbb6cbb398d054 509 PANTHER PTHR24220 3 344 2.8E-82 T 23-04-2016 DC74_RS13185 c901831232ac34973aee6d69c78dc4f5 423 Gene3D G3DSA:3.30.565.10 333 422 4.8E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS13185 c901831232ac34973aee6d69c78dc4f5 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 334 421 1.0E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS13185 c901831232ac34973aee6d69c78dc4f5 423 SUPERFAMILY SSF55874 301 421 3.67E-15 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS13185 c901831232ac34973aee6d69c78dc4f5 423 PANTHER PTHR24421 202 422 1.8E-74 T 23-04-2016 DC74_RS13185 c901831232ac34973aee6d69c78dc4f5 423 PANTHER PTHR24421:SF19 202 422 1.8E-74 T 23-04-2016 DC74_RS13185 c901831232ac34973aee6d69c78dc4f5 423 Pfam PF13796 Putative sensor 20 198 4.6E-18 T 23-04-2016 IPR025828 Putative sensor domain DC74_RS13185 c901831232ac34973aee6d69c78dc4f5 423 Pfam PF07730 Histidine kinase 226 293 1.3E-14 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 242 541 6.3E-108 T 23-04-2016 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 Gene3D G3DSA:3.30.930.10 756 1099 1.7E-98 T 23-04-2016 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 Pfam PF01336 OB-fold nucleic acid binding domain 666 741 1.5E-13 T 23-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 Gene3D G3DSA:2.40.50.140 615 752 1.1E-42 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 PANTHER PTHR22594 603 1104 2.4E-209 T 23-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 616 1102 2.1E-148 T 23-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 SUPERFAMILY SSF55681 759 1102 3.06E-98 T 23-04-2016 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 18 224 2.4E-52 T 23-04-2016 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 PANTHER PTHR22594:SF4 603 1104 2.4E-209 T 23-04-2016 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 SUPERFAMILY SSF50249 614 752 6.37E-35 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 PRINTS PR00982 Lysyl-tRNA synthetase signature 796 806 1.1E-29 T 23-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 PRINTS PR00982 Lysyl-tRNA synthetase signature 841 854 1.1E-29 T 23-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 PRINTS PR00982 Lysyl-tRNA synthetase signature 987 1003 1.1E-29 T 23-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 PRINTS PR00982 Lysyl-tRNA synthetase signature 812 828 1.1E-29 T 23-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 PRINTS PR00982 Lysyl-tRNA synthetase signature 859 876 1.1E-29 T 23-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 Pfam PF00152 tRNA synthetases class II (D, K and N) 761 1101 5.8E-69 T 23-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS33845 1907faf242adfe0e1a6e71ce801b4113 1104 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 620 1104 36.126 T 23-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 DC74_RS17385 eb6cc9bfe320863b112c74ab1db823bd 425 PANTHER PTHR23501:SF79 30 421 2.4E-136 T 23-04-2016 DC74_RS17385 eb6cc9bfe320863b112c74ab1db823bd 425 PANTHER PTHR23501 30 421 2.4E-136 T 23-04-2016 DC74_RS17385 eb6cc9bfe320863b112c74ab1db823bd 425 Pfam PF07690 Major Facilitator Superfamily 44 336 2.7E-27 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS17385 eb6cc9bfe320863b112c74ab1db823bd 425 SUPERFAMILY SSF103473 21 417 7.85E-48 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS17385 eb6cc9bfe320863b112c74ab1db823bd 425 Gene3D G3DSA:1.20.1250.20 37 214 1.7E-18 T 23-04-2016 DC74_RS17385 eb6cc9bfe320863b112c74ab1db823bd 425 Gene3D G3DSA:1.20.1250.20 244 413 9.6E-8 T 23-04-2016 DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 326 40.721 T 23-04-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2 DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 SUPERFAMILY SSF52374 1 325 4.22E-98 T 23-04-2016 DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 Gene3D G3DSA:1.10.240.10 208 301 8.3E-14 T 23-04-2016 DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 Pfam PF00579 tRNA synthetases class I (W and Y) 1 277 1.7E-77 T 23-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 PANTHER PTHR10055 1 329 4.5E-175 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 139 160 2.1E-27 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 192 202 2.1E-27 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 12 28 2.1E-27 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 62 81 2.1E-27 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 PANTHER PTHR10055:SF10 1 329 4.5E-175 T 23-04-2016 DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 7 17 - T 23-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 Gene3D G3DSA:3.40.50.620 1 207 1.7E-91 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS24710 ace0ca955a9a5e9ce4f2d49fd115a651 330 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 1 325 1.3E-105 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 DC74_RS38125 ba0ae851b0fed838c26793fb4cbfe71c 245 SUPERFAMILY SSF56784 27 230 1.84E-30 T 23-04-2016 IPR023214 HAD-like domain DC74_RS38125 ba0ae851b0fed838c26793fb4cbfe71c 245 Pfam PF13419 Haloacid dehalogenase-like hydrolase 107 218 1.9E-10 T 23-04-2016 IPR023214 HAD-like domain DC74_RS38125 ba0ae851b0fed838c26793fb4cbfe71c 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 166 182 7.9E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS38125 ba0ae851b0fed838c26793fb4cbfe71c 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 184 204 7.9E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS38125 ba0ae851b0fed838c26793fb4cbfe71c 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 149 7.9E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS38125 ba0ae851b0fed838c26793fb4cbfe71c 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 28 39 7.9E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS38125 ba0ae851b0fed838c26793fb4cbfe71c 245 Gene3D G3DSA:3.40.50.1000 28 223 1.4E-26 T 23-04-2016 IPR023214 HAD-like domain DC74_RS38125 ba0ae851b0fed838c26793fb4cbfe71c 245 PANTHER PTHR12725 11 219 1.5E-20 T 23-04-2016 DC74_RS38125 ba0ae851b0fed838c26793fb4cbfe71c 245 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 169 213 3.6E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS23705 9c68bee4557466a59dcdc4b51176686a 262 Hamap MF_00991 Futalosine hydrolase [mqnB]. 42 241 25.469 T 23-04-2016 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374|UniPathway: UPA00079 DC74_RS23705 9c68bee4557466a59dcdc4b51176686a 262 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 4 238 2.4E-63 T 23-04-2016 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374|UniPathway: UPA00079 DC74_RS23705 9c68bee4557466a59dcdc4b51176686a 262 Gene3D G3DSA:3.40.50.1580 1 243 6.4E-49 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS23705 9c68bee4557466a59dcdc4b51176686a 262 SUPERFAMILY SSF53167 59 223 5.15E-25 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS23705 9c68bee4557466a59dcdc4b51176686a 262 Pfam PF01048 Phosphorylase superfamily 61 219 2.9E-12 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS37895 29c31d9727ee9f987717f4367f8cf468 477 Gene3D G3DSA:3.30.420.40 236 425 1.6E-30 T 23-04-2016 DC74_RS37895 29c31d9727ee9f987717f4367f8cf468 477 TIGRFAM TIGR01312 XylB: xylulokinase 6 426 3.7E-119 T 23-04-2016 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 DC74_RS37895 29c31d9727ee9f987717f4367f8cf468 477 SUPERFAMILY SSF53067 4 234 3.11E-48 T 23-04-2016 DC74_RS37895 29c31d9727ee9f987717f4367f8cf468 477 PANTHER PTHR10196:SF67 1 424 6.1E-117 T 23-04-2016 DC74_RS37895 29c31d9727ee9f987717f4367f8cf468 477 Gene3D G3DSA:3.30.420.40 1 232 5.1E-45 T 23-04-2016 DC74_RS37895 29c31d9727ee9f987717f4367f8cf468 477 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 241 423 6.1E-27 T 23-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 DC74_RS37895 29c31d9727ee9f987717f4367f8cf468 477 PIRSF PIRSF000538 1 433 1.3E-82 T 23-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 DC74_RS37895 29c31d9727ee9f987717f4367f8cf468 477 SUPERFAMILY SSF53067 235 443 2.59E-41 T 23-04-2016 DC74_RS37895 29c31d9727ee9f987717f4367f8cf468 477 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 232 1.2E-38 T 23-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 DC74_RS37895 29c31d9727ee9f987717f4367f8cf468 477 PANTHER PTHR10196 1 424 6.1E-117 T 23-04-2016 DC74_RS00625 ba3393b32bc68569876d2268f07790f5 236 Pfam PF12867 DinB superfamily 80 225 2.6E-14 T 23-04-2016 IPR024775 DinB-like domain DC74_RS00625 ba3393b32bc68569876d2268f07790f5 236 Gene3D G3DSA:1.20.120.450 104 224 4.0E-7 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS00625 ba3393b32bc68569876d2268f07790f5 236 Pfam PF00805 Pentapeptide repeats (8 copies) 4 27 2.5E-4 T 23-04-2016 IPR001646 Pentapeptide repeat DC74_RS00625 ba3393b32bc68569876d2268f07790f5 236 SUPERFAMILY SSF109854 77 225 3.21E-13 T 23-04-2016 DC74_RS10395 adb703b653d6deab805f4e4054f8ae90 518 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 16 268 1.1E-79 T 23-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 DC74_RS10395 adb703b653d6deab805f4e4054f8ae90 518 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 379 399 - T 23-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 DC74_RS10395 adb703b653d6deab805f4e4054f8ae90 518 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 14 513 1.3E-226 T 23-04-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 DC74_RS10395 adb703b653d6deab805f4e4054f8ae90 518 PANTHER PTHR10196 14 518 5.2E-273 T 23-04-2016 DC74_RS10395 adb703b653d6deab805f4e4054f8ae90 518 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 277 467 3.0E-64 T 23-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 DC74_RS10395 adb703b653d6deab805f4e4054f8ae90 518 SUPERFAMILY SSF53067 271 514 6.15E-81 T 23-04-2016 DC74_RS10395 adb703b653d6deab805f4e4054f8ae90 518 Gene3D G3DSA:3.30.420.40 271 515 6.2E-102 T 23-04-2016 DC74_RS10395 adb703b653d6deab805f4e4054f8ae90 518 PANTHER PTHR10196:SF69 14 518 5.2E-273 T 23-04-2016 DC74_RS10395 adb703b653d6deab805f4e4054f8ae90 518 Gene3D G3DSA:3.30.420.40 13 269 2.2E-106 T 23-04-2016 DC74_RS10395 adb703b653d6deab805f4e4054f8ae90 518 PIRSF PIRSF000538 14 518 3.6E-165 T 23-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 DC74_RS10395 adb703b653d6deab805f4e4054f8ae90 518 SUPERFAMILY SSF53067 15 271 2.85E-90 T 23-04-2016 DC74_RS10395 adb703b653d6deab805f4e4054f8ae90 518 Hamap MF_00186 Glycerol kinase [glpK]. 13 514 55.6 T 23-04-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 DC74_RS00055 3e275d078341b04ec6bd90541a0d2123 236 PANTHER PTHR14239 1 38 1.4E-16 T 23-04-2016 DC74_RS00055 3e275d078341b04ec6bd90541a0d2123 236 PANTHER PTHR14239 54 211 1.4E-16 T 23-04-2016 DC74_RS00055 3e275d078341b04ec6bd90541a0d2123 236 SUPERFAMILY SSF51735 1 226 1.17E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00055 3e275d078341b04ec6bd90541a0d2123 236 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 106 5.3E-6 T 23-04-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal DC74_RS00055 3e275d078341b04ec6bd90541a0d2123 236 Gene3D G3DSA:3.40.50.720 67 213 2.5E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00055 3e275d078341b04ec6bd90541a0d2123 236 Gene3D G3DSA:3.40.50.720 1 33 2.5E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15805 d11bdf6d1a5e2fffef9326b10252c5b4 472 PANTHER PTHR11010:SF11 1 224 5.3E-34 T 23-04-2016 DC74_RS15805 d11bdf6d1a5e2fffef9326b10252c5b4 472 Pfam PF05576 PS-10 peptidase S37 31 449 3.4E-180 T 23-04-2016 IPR008761 Peptidase S37, tripeptidyl aminopeptidase DC74_RS15805 d11bdf6d1a5e2fffef9326b10252c5b4 472 SUPERFAMILY SSF53474 363 420 3.18E-12 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS15805 d11bdf6d1a5e2fffef9326b10252c5b4 472 SUPERFAMILY SSF53474 92 213 3.18E-12 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS15805 d11bdf6d1a5e2fffef9326b10252c5b4 472 PANTHER PTHR11010 1 224 5.3E-34 T 23-04-2016 DC74_RS15805 d11bdf6d1a5e2fffef9326b10252c5b4 472 Gene3D G3DSA:3.40.50.1820 91 251 3.0E-9 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS15805 d11bdf6d1a5e2fffef9326b10252c5b4 472 Gene3D G3DSA:3.40.50.1820 353 420 3.0E-9 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS17395 89a0ec4bc705ef4d88f16579cbea0eec 274 PANTHER PTHR10245:SF7 1 270 4.0E-63 T 23-04-2016 DC74_RS17395 89a0ec4bc705ef4d88f16579cbea0eec 274 SUPERFAMILY SSF47413 12 72 4.56E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS17395 89a0ec4bc705ef4d88f16579cbea0eec 274 Gene3D G3DSA:1.10.260.40 8 68 3.6E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS17395 89a0ec4bc705ef4d88f16579cbea0eec 274 Pfam PF13560 Helix-turn-helix domain 15 69 2.6E-12 T 23-04-2016 DC74_RS17395 89a0ec4bc705ef4d88f16579cbea0eec 274 PANTHER PTHR10245 1 270 4.0E-63 T 23-04-2016 DC74_RS17395 89a0ec4bc705ef4d88f16579cbea0eec 274 SMART SM00530 17 72 4.1E-11 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS28665 83c2efce72e48e25b8ade2f9bcdb7668 279 Pfam PF13464 Domain of unknown function (DUF4115) 200 270 1.0E-18 T 23-04-2016 IPR025194 Domain of unknown function DUF4115 DC74_RS28665 83c2efce72e48e25b8ade2f9bcdb7668 279 PANTHER PTHR34475 11 279 4.2E-40 T 23-04-2016 DC74_RS28665 83c2efce72e48e25b8ade2f9bcdb7668 279 Gene3D G3DSA:1.10.260.40 19 93 4.8E-5 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS28665 83c2efce72e48e25b8ade2f9bcdb7668 279 Pfam PF13413 Helix-turn-helix domain 28 87 2.5E-19 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS28665 83c2efce72e48e25b8ade2f9bcdb7668 279 PANTHER PTHR34475:SF1 11 279 4.2E-40 T 23-04-2016 DC74_RS29460 37b1d2c64db32464a24e978ca180eba7 356 Gene3D G3DSA:3.60.130.10 58 346 1.4E-56 T 23-04-2016 DC74_RS29460 37b1d2c64db32464a24e978ca180eba7 356 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 160 334 1.4E-8 T 23-04-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 DC74_RS29460 37b1d2c64db32464a24e978ca180eba7 356 SUPERFAMILY SSF51197 26 342 4.58E-41 T 23-04-2016 DC74_RS29460 37b1d2c64db32464a24e978ca180eba7 356 PIRSF PIRSF019543 9 355 2.0E-104 T 23-04-2016 IPR014503 Clavaminate synthase GO:0005506|GO:0017000|GO:0033758|GO:0055114 DC74_RS38690 f0d77452e6fdda467c620784efc60cb7 584 Gene3D G3DSA:1.20.1560.10 6 320 6.2E-54 T 23-04-2016 DC74_RS38690 f0d77452e6fdda467c620784efc60cb7 584 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS38690 f0d77452e6fdda467c620784efc60cb7 584 PANTHER PTHR24221 3 579 6.2E-196 T 23-04-2016 DC74_RS38690 f0d77452e6fdda467c620784efc60cb7 584 SMART SM00382 360 546 2.1E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS38690 f0d77452e6fdda467c620784efc60cb7 584 SUPERFAMILY SSF90123 6 320 9.29E-61 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS38690 f0d77452e6fdda467c620784efc60cb7 584 PANTHER PTHR24221:SF190 3 579 6.2E-196 T 23-04-2016 DC74_RS38690 f0d77452e6fdda467c620784efc60cb7 584 Gene3D G3DSA:3.40.50.300 336 576 6.9E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38690 f0d77452e6fdda467c620784efc60cb7 584 Pfam PF00005 ABC transporter 351 499 4.4E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS38690 f0d77452e6fdda467c620784efc60cb7 584 Pfam PF00664 ABC transporter transmembrane region 20 288 2.8E-33 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS38690 f0d77452e6fdda467c620784efc60cb7 584 SUPERFAMILY SSF52540 329 570 1.2E-77 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18270 06bf6ad19e7b97c9b2d7e1a9ec05d264 263 PANTHER PTHR11941 6 234 3.4E-35 T 23-04-2016 DC74_RS18270 06bf6ad19e7b97c9b2d7e1a9ec05d264 263 SUPERFAMILY SSF52096 4 248 1.24E-48 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS18270 06bf6ad19e7b97c9b2d7e1a9ec05d264 263 Gene3D G3DSA:3.90.226.10 6 228 1.0E-47 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS18270 06bf6ad19e7b97c9b2d7e1a9ec05d264 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 228 2.0E-31 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS31475 140a08b177a43502f95c380d35d008d8 297 Gene3D G3DSA:1.10.10.10 5 87 1.3E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31475 140a08b177a43502f95c380d35d008d8 297 SUPERFAMILY SSF53850 94 293 7.36E-31 T 23-04-2016 DC74_RS31475 140a08b177a43502f95c380d35d008d8 297 Gene3D G3DSA:3.40.190.10 178 264 9.5E-18 T 23-04-2016 DC74_RS31475 140a08b177a43502f95c380d35d008d8 297 Pfam PF03466 LysR substrate binding domain 91 293 3.4E-36 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS31475 140a08b177a43502f95c380d35d008d8 297 Gene3D G3DSA:3.40.190.10 91 177 7.1E-17 T 23-04-2016 DC74_RS31475 140a08b177a43502f95c380d35d008d8 297 PANTHER PTHR30346:SF7 1 292 2.1E-90 T 23-04-2016 DC74_RS31475 140a08b177a43502f95c380d35d008d8 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.1E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS31475 140a08b177a43502f95c380d35d008d8 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.1E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS31475 140a08b177a43502f95c380d35d008d8 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.1E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS31475 140a08b177a43502f95c380d35d008d8 297 PANTHER PTHR30346 1 292 2.1E-90 T 23-04-2016 DC74_RS31475 140a08b177a43502f95c380d35d008d8 297 SUPERFAMILY SSF46785 5 86 4.76E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31475 140a08b177a43502f95c380d35d008d8 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.5E-22 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS31510 ce9fb4bf51c2c63f8f7953e5801bd863 269 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS31510 ce9fb4bf51c2c63f8f7953e5801bd863 269 Gene3D G3DSA:3.40.50.300 2 234 1.1E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS31510 ce9fb4bf51c2c63f8f7953e5801bd863 269 PANTHER PTHR24220:SF520 6 256 1.5E-161 T 23-04-2016 DC74_RS31510 ce9fb4bf51c2c63f8f7953e5801bd863 269 SMART SM00382 29 222 1.0E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS31510 ce9fb4bf51c2c63f8f7953e5801bd863 269 Pfam PF00005 ABC transporter 20 174 6.8E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS31510 ce9fb4bf51c2c63f8f7953e5801bd863 269 PANTHER PTHR24220 6 256 1.5E-161 T 23-04-2016 DC74_RS31510 ce9fb4bf51c2c63f8f7953e5801bd863 269 SUPERFAMILY SSF52540 4 225 3.59E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29475 33a2ba72c3a120348a88ae3df0275c4d 262 SUPERFAMILY SSF53474 9 254 1.04E-39 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS29475 33a2ba72c3a120348a88ae3df0275c4d 262 Gene3D G3DSA:3.40.50.1820 14 259 2.6E-28 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS29475 33a2ba72c3a120348a88ae3df0275c4d 262 PANTHER PTHR11487 13 241 3.3E-58 T 23-04-2016 IPR012223 Thioesterase type II, NRPS/PKS/S-FAS GO:0009058 DC74_RS29475 33a2ba72c3a120348a88ae3df0275c4d 262 Pfam PF00975 Thioesterase domain 26 254 9.7E-36 T 23-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 DC74_RS03445 72a404b8580e437750cf235ed0f88866 282 PANTHER PTHR14194 1 270 2.0E-75 T 23-04-2016 DC74_RS03445 72a404b8580e437750cf235ed0f88866 282 SUPERFAMILY SSF51735 4 271 3.8E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03445 72a404b8580e437750cf235ed0f88866 282 Gene3D G3DSA:3.40.50.720 4 213 2.7E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03445 72a404b8580e437750cf235ed0f88866 282 PANTHER PTHR14194:SF59 1 270 2.0E-75 T 23-04-2016 DC74_RS03445 72a404b8580e437750cf235ed0f88866 282 Pfam PF13460 NAD(P)H-binding 11 162 4.9E-11 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS23460 1e95e8ded8c5c5b82a9fd5167cd1c2b0 142 SUPERFAMILY SSF75620 11 103 5.1E-12 T 23-04-2016 DC74_RS23460 1e95e8ded8c5c5b82a9fd5167cd1c2b0 142 Gene3D G3DSA:3.30.160.200 10 110 2.2E-27 T 23-04-2016 DC74_RS23460 1e95e8ded8c5c5b82a9fd5167cd1c2b0 142 Pfam PF00472 RF-1 domain 10 136 9.7E-23 T 23-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 DC74_RS23460 1e95e8ded8c5c5b82a9fd5167cd1c2b0 142 PANTHER PTHR11075 10 136 1.1E-34 T 23-04-2016 DC74_RS08435 77cd2056d56de79ab0cb03b6c0090e94 516 PANTHER PTHR24096:SF106 20 516 1.7E-162 T 23-04-2016 DC74_RS08435 77cd2056d56de79ab0cb03b6c0090e94 516 Gene3D G3DSA:3.40.50.980 7 174 1.6E-27 T 23-04-2016 DC74_RS08435 77cd2056d56de79ab0cb03b6c0090e94 516 SUPERFAMILY SSF56801 6 511 3.53E-118 T 23-04-2016 DC74_RS08435 77cd2056d56de79ab0cb03b6c0090e94 516 Pfam PF00501 AMP-binding enzyme 8 411 3.4E-66 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS08435 77cd2056d56de79ab0cb03b6c0090e94 516 Gene3D G3DSA:3.40.50.980 201 317 2.3E-26 T 23-04-2016 DC74_RS08435 77cd2056d56de79ab0cb03b6c0090e94 516 Gene3D G3DSA:3.30.300.30 407 509 1.1E-30 T 23-04-2016 DC74_RS08435 77cd2056d56de79ab0cb03b6c0090e94 516 Gene3D G3DSA:2.30.38.10 328 401 5.1E-13 T 23-04-2016 DC74_RS08435 77cd2056d56de79ab0cb03b6c0090e94 516 PANTHER PTHR24096 20 516 1.7E-162 T 23-04-2016 DC74_RS08435 77cd2056d56de79ab0cb03b6c0090e94 516 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 498 6.5E-19 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS27365 3e960c9fc29b89b4b5df67f760093f6b 394 PANTHER PTHR30582:SF2 34 392 5.5E-119 T 23-04-2016 DC74_RS27365 3e960c9fc29b89b4b5df67f760093f6b 394 Pfam PF03734 L,D-transpeptidase catalytic domain 238 367 4.4E-14 T 23-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 DC74_RS27365 3e960c9fc29b89b4b5df67f760093f6b 394 Gene3D G3DSA:2.40.440.10 240 368 3.7E-19 T 23-04-2016 DC74_RS27365 3e960c9fc29b89b4b5df67f760093f6b 394 SUPERFAMILY SSF141523 240 367 1.19E-23 T 23-04-2016 DC74_RS27365 3e960c9fc29b89b4b5df67f760093f6b 394 PANTHER PTHR30582 34 392 5.5E-119 T 23-04-2016 DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 7 348 2.3E-115 T 23-04-2016 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 SMART SM00998 363 438 6.1E-9 T 23-04-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 Gene3D G3DSA:1.10.275.10 10 95 2.2E-24 T 23-04-2016 IPR024083 Fumarase/histidase, N-terminal DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 Pfam PF00206 Lyase 26 300 6.4E-32 T 23-04-2016 IPR022761 Fumarate lyase, N-terminal DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 PANTHER PTHR11444 19 441 5.0E-141 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 Gene3D G3DSA:1.10.40.30 370 438 8.9E-15 T 23-04-2016 DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 3.7E-21 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 PRINTS PR00149 Fumarate lyase superfamily signature 275 291 3.7E-21 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 PRINTS PR00149 Fumarate lyase superfamily signature 93 111 3.7E-21 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 PRINTS PR00149 Fumarate lyase superfamily signature 233 260 3.7E-21 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 ProSitePatterns PS00163 Fumarate lyases signature. 275 284 - T 23-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 PANTHER PTHR11444:SF21 19 441 5.0E-141 T 23-04-2016 DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 Pfam PF10397 Adenylosuccinate lyase C-terminus 364 437 2.8E-10 T 23-04-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 SUPERFAMILY SSF48557 17 439 1.05E-81 T 23-04-2016 IPR008948 L-Aspartase-like GO:0003824 DC74_RS02320 bcf5ee96fc1d2faecc3996c91ba49513 441 Gene3D G3DSA:1.20.200.10 96 369 2.7E-91 T 23-04-2016 DC74_RS28055 93aca6b9a5d6b5498a9419da02d59295 499 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 26 443 1.4E-78 T 23-04-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 DC74_RS28055 93aca6b9a5d6b5498a9419da02d59295 499 PANTHER PTHR31806 12 491 7.2E-134 T 23-04-2016 DC74_RS28055 93aca6b9a5d6b5498a9419da02d59295 499 PANTHER PTHR31806:SF2 12 491 7.2E-134 T 23-04-2016 DC74_RS28055 93aca6b9a5d6b5498a9419da02d59295 499 PIRSF PIRSF002744 2 487 1.5E-95 T 23-04-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 DC74_RS15035 c4481c1777001b8f3351918b8fbc5a0b 338 PANTHER PTHR34824 1 337 2.2E-112 T 23-04-2016 DC74_RS15035 c4481c1777001b8f3351918b8fbc5a0b 338 Gene3D G3DSA:3.30.450.40 176 337 2.2E-44 T 23-04-2016 IPR029016 GAF domain-like DC74_RS15035 c4481c1777001b8f3351918b8fbc5a0b 338 Gene3D G3DSA:1.10.10.10 1 84 3.5E-36 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS15035 c4481c1777001b8f3351918b8fbc5a0b 338 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 334 5.2E-102 T 23-04-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 DC74_RS15035 c4481c1777001b8f3351918b8fbc5a0b 338 Pfam PF01628 HrcA protein C terminal domain 103 321 1.7E-62 T 23-04-2016 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 DC74_RS15035 c4481c1777001b8f3351918b8fbc5a0b 338 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 28.561 T 23-04-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 DC74_RS15035 c4481c1777001b8f3351918b8fbc5a0b 338 SUPERFAMILY SSF55781 71 336 3.33E-58 T 23-04-2016 IPR029016 GAF domain-like DC74_RS15035 c4481c1777001b8f3351918b8fbc5a0b 338 PIRSF PIRSF005485 1 338 2.9E-102 T 23-04-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 DC74_RS15035 c4481c1777001b8f3351918b8fbc5a0b 338 SUPERFAMILY SSF46785 1 82 3.98E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09110 0bf09b3d2156b725c4637a8618357eb7 330 PANTHER PTHR42110:SF1 14 296 9.0E-54 T 23-04-2016 DC74_RS09110 0bf09b3d2156b725c4637a8618357eb7 330 PANTHER PTHR42110 14 296 9.0E-54 T 23-04-2016 DC74_RS09110 0bf09b3d2156b725c4637a8618357eb7 330 Pfam PF06089 L-asparaginase II 17 316 2.3E-106 T 23-04-2016 IPR010349 L-asparaginase II DC74_RS13365 3eb73edeb7b3601ba24c868af619943d 248 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 37 131 2.4E-21 T 23-04-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal DC74_RS13365 3eb73edeb7b3601ba24c868af619943d 248 PANTHER PTHR14239 1 235 8.9E-52 T 23-04-2016 DC74_RS13365 3eb73edeb7b3601ba24c868af619943d 248 SUPERFAMILY SSF51735 37 242 3.1E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS13365 3eb73edeb7b3601ba24c868af619943d 248 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 35 245 5.0E-78 T 23-04-2016 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 DC74_RS13365 3eb73edeb7b3601ba24c868af619943d 248 Gene3D G3DSA:3.40.50.720 37 240 7.6E-60 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29335 6e398eb97ca5a33c847450f661d57e4d 899 Gene3D G3DSA:3.60.21.10 184 430 3.8E-51 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS29335 6e398eb97ca5a33c847450f661d57e4d 899 SUPERFAMILY SSF56091 704 806 2.12E-9 T 23-04-2016 DC74_RS29335 6e398eb97ca5a33c847450f661d57e4d 899 SUPERFAMILY SSF56091 527 623 2.12E-9 T 23-04-2016 DC74_RS29335 6e398eb97ca5a33c847450f661d57e4d 899 SUPERFAMILY SSF52540 16 146 2.51E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29335 6e398eb97ca5a33c847450f661d57e4d 899 Pfam PF00149 Calcineurin-like phosphoesterase 188 394 9.1E-12 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS29335 6e398eb97ca5a33c847450f661d57e4d 899 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 840 899 1.5E-31 T 23-04-2016 IPR032390 Polynucleotide kinase-phosphatase, C-terminal DC74_RS29335 6e398eb97ca5a33c847450f661d57e4d 899 Gene3D G3DSA:3.40.50.300 16 141 2.4E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29335 6e398eb97ca5a33c847450f661d57e4d 899 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 9 746 0.0 T 23-04-2016 IPR024028 Polynucleotide kinase-phosphatase, bacterial DC74_RS29335 6e398eb97ca5a33c847450f661d57e4d 899 SUPERFAMILY SSF56300 181 421 4.6E-41 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS29335 6e398eb97ca5a33c847450f661d57e4d 899 Pfam PF13671 AAA domain 16 143 2.5E-23 T 23-04-2016 DC74_RS29335 6e398eb97ca5a33c847450f661d57e4d 899 PANTHER PTHR24032 173 437 1.3E-51 T 23-04-2016 DC74_RS29335 6e398eb97ca5a33c847450f661d57e4d 899 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 472 836 8.3E-133 T 23-04-2016 IPR032380 Polynucleotide kinase-phosphatase, ligase domain DC74_RS20535 60e7f8841b6f31d0fa4e70cdb2e7b1e9 327 PANTHER PTHR30346 16 324 2.0E-68 T 23-04-2016 DC74_RS20535 60e7f8841b6f31d0fa4e70cdb2e7b1e9 327 Gene3D G3DSA:1.10.10.10 17 100 1.6E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20535 60e7f8841b6f31d0fa4e70cdb2e7b1e9 327 Pfam PF03466 LysR substrate binding domain 102 306 2.2E-24 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS20535 60e7f8841b6f31d0fa4e70cdb2e7b1e9 327 PANTHER PTHR30346:SF14 16 324 2.0E-68 T 23-04-2016 DC74_RS20535 60e7f8841b6f31d0fa4e70cdb2e7b1e9 327 SUPERFAMILY SSF53850 103 307 6.36E-22 T 23-04-2016 DC74_RS20535 60e7f8841b6f31d0fa4e70cdb2e7b1e9 327 Gene3D G3DSA:3.40.190.10 190 277 2.2E-7 T 23-04-2016 DC74_RS20535 60e7f8841b6f31d0fa4e70cdb2e7b1e9 327 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 77 2.5E-14 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS20535 60e7f8841b6f31d0fa4e70cdb2e7b1e9 327 SUPERFAMILY SSF46785 17 99 5.86E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20535 60e7f8841b6f31d0fa4e70cdb2e7b1e9 327 Gene3D G3DSA:3.40.190.10 105 189 7.1E-14 T 23-04-2016 DC74_RS16615 9ca1ab0891c047dce5f9015ccfe64e3f 93 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 2.2E-8 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS16615 9ca1ab0891c047dce5f9015ccfe64e3f 93 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 2.2E-8 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS16615 9ca1ab0891c047dce5f9015ccfe64e3f 93 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 2.2E-8 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS16615 9ca1ab0891c047dce5f9015ccfe64e3f 93 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.5E-27 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS16615 9ca1ab0891c047dce5f9015ccfe64e3f 93 SUPERFAMILY SSF47729 1 91 3.24E-26 T 23-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 DC74_RS16615 9ca1ab0891c047dce5f9015ccfe64e3f 93 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 23-04-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 DC74_RS16615 9ca1ab0891c047dce5f9015ccfe64e3f 93 PANTHER PTHR33175 1 92 1.6E-34 T 23-04-2016 DC74_RS16615 9ca1ab0891c047dce5f9015ccfe64e3f 93 Gene3D G3DSA:4.10.520.10 1 91 6.4E-29 T 23-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 DC74_RS16615 9ca1ab0891c047dce5f9015ccfe64e3f 93 SMART SM00411 1 91 7.7E-38 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 DC74_RS03285 9ba19f336320518844243d7271469659 224 SUPERFAMILY SSF52317 4 223 1.94E-59 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS03285 9ba19f336320518844243d7271469659 224 PANTHER PTHR11019 16 60 3.5E-30 T 23-04-2016 DC74_RS03285 9ba19f336320518844243d7271469659 224 PANTHER PTHR11019 83 222 3.5E-30 T 23-04-2016 DC74_RS03285 9ba19f336320518844243d7271469659 224 Pfam PF01965 DJ-1/PfpI family 22 221 9.1E-14 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS03285 9ba19f336320518844243d7271469659 224 Gene3D G3DSA:3.40.50.880 2 224 6.2E-72 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS03285 9ba19f336320518844243d7271469659 224 PANTHER PTHR11019:SF97 16 60 3.5E-30 T 23-04-2016 DC74_RS03285 9ba19f336320518844243d7271469659 224 PANTHER PTHR11019:SF97 83 222 3.5E-30 T 23-04-2016 DC74_RS19335 7243fed227e699e521dbf094c1484793 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.6E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19335 7243fed227e699e521dbf094c1484793 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 2.6E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19335 7243fed227e699e521dbf094c1484793 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.6E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19335 7243fed227e699e521dbf094c1484793 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 6 240 2.8E-60 T 23-04-2016 DC74_RS19335 7243fed227e699e521dbf094c1484793 245 Gene3D G3DSA:3.40.50.720 1 241 6.3E-78 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19335 7243fed227e699e521dbf094c1484793 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.0E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19335 7243fed227e699e521dbf094c1484793 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 16 1.0E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19335 7243fed227e699e521dbf094c1484793 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 1.0E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19335 7243fed227e699e521dbf094c1484793 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.0E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19335 7243fed227e699e521dbf094c1484793 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.0E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19335 7243fed227e699e521dbf094c1484793 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.0E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19335 7243fed227e699e521dbf094c1484793 245 PANTHER PTHR24322 149 185 1.1E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19335 7243fed227e699e521dbf094c1484793 245 PANTHER PTHR24322 4 133 1.1E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19335 7243fed227e699e521dbf094c1484793 245 SUPERFAMILY SSF51735 1 241 2.7E-75 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19335 7243fed227e699e521dbf094c1484793 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 180 0.01 T 23-04-2016 DC74_RS06725 8be5f963ccb9a11f7223efaf45367c06 296 SUPERFAMILY SSF46785 2 112 1.14E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06725 8be5f963ccb9a11f7223efaf45367c06 296 Gene3D G3DSA:3.40.190.10 179 262 8.5E-18 T 23-04-2016 DC74_RS06725 8be5f963ccb9a11f7223efaf45367c06 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 9.1E-25 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS06725 8be5f963ccb9a11f7223efaf45367c06 296 Pfam PF03466 LysR substrate binding domain 91 293 2.3E-43 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS06725 8be5f963ccb9a11f7223efaf45367c06 296 SUPERFAMILY SSF53850 92 294 9.0E-43 T 23-04-2016 DC74_RS06725 8be5f963ccb9a11f7223efaf45367c06 296 Gene3D G3DSA:1.10.10.10 3 86 2.0E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06725 8be5f963ccb9a11f7223efaf45367c06 296 PANTHER PTHR30346 1 293 2.5E-87 T 23-04-2016 DC74_RS06725 8be5f963ccb9a11f7223efaf45367c06 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.6E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS06725 8be5f963ccb9a11f7223efaf45367c06 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.6E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS06725 8be5f963ccb9a11f7223efaf45367c06 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.6E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS06725 8be5f963ccb9a11f7223efaf45367c06 296 Gene3D G3DSA:3.40.190.10 92 178 6.1E-18 T 23-04-2016 DC74_RS06725 8be5f963ccb9a11f7223efaf45367c06 296 PANTHER PTHR30346:SF3 1 293 2.5E-87 T 23-04-2016 DC74_RS36355 fc95f04729766b159e2dbc9d3855d53d 309 Gene3D G3DSA:3.90.190.10 175 234 2.5E-16 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS36355 fc95f04729766b159e2dbc9d3855d53d 309 Gene3D G3DSA:3.90.190.10 54 138 2.5E-16 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS36355 fc95f04729766b159e2dbc9d3855d53d 309 PANTHER PTHR31126 167 309 1.9E-48 T 23-04-2016 DC74_RS36355 fc95f04729766b159e2dbc9d3855d53d 309 PANTHER PTHR31126:SF21 37 131 1.9E-48 T 23-04-2016 DC74_RS36355 fc95f04729766b159e2dbc9d3855d53d 309 SUPERFAMILY SSF52799 51 308 3.31E-48 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS36355 fc95f04729766b159e2dbc9d3855d53d 309 PANTHER PTHR31126 37 131 1.9E-48 T 23-04-2016 DC74_RS36355 fc95f04729766b159e2dbc9d3855d53d 309 Pfam PF13350 Tyrosine phosphatase family 52 308 8.7E-61 T 23-04-2016 IPR026893 Tyrosine/serine-protein phosphatase IphP-type DC74_RS36355 fc95f04729766b159e2dbc9d3855d53d 309 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 199 209 - T 23-04-2016 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 DC74_RS36355 fc95f04729766b159e2dbc9d3855d53d 309 PANTHER PTHR31126:SF21 167 309 1.9E-48 T 23-04-2016 DC74_RS30085 a70df60a0e11937ded32a10433304629 277 PIRSF PIRSF017393 2 273 8.4E-82 T 23-04-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type DC74_RS30085 a70df60a0e11937ded32a10433304629 277 SUPERFAMILY SSF53335 17 252 2.48E-38 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS30085 a70df60a0e11937ded32a10433304629 277 Pfam PF04672 S-adenosyl methyltransferase 8 271 8.7E-85 T 23-04-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type DC74_RS30085 a70df60a0e11937ded32a10433304629 277 Gene3D G3DSA:3.40.50.150 5 271 5.0E-93 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 Pfam PF01926 50S ribosome-binding GTPase 51 165 2.7E-25 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 Pfam PF01926 50S ribosome-binding GTPase 225 343 8.3E-22 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 SUPERFAMILY SSF52540 183 481 7.25E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 51 170 7.5E-24 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 224 386 3.1E-20 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 Hamap MF_00195 GTPase Der [der]. 48 480 35.241 T 23-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 PANTHER PTHR11649:SF5 12 482 2.1E-129 T 23-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 49 477 1.5E-156 T 23-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 Gene3D G3DSA:3.40.50.300 49 214 7.1E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 Gene3D G3DSA:3.40.50.300 224 404 2.6E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 SMART SM00382 222 365 0.028 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 SMART SM00382 47 185 0.71 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 275 290 6.5E-6 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 226 246 6.5E-6 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 SUPERFAMILY SSF52540 50 213 4.88E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 PIRSF PIRSF006485 47 485 1.2E-157 T 23-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 Gene3D G3DSA:3.30.300.20 405 479 9.5E-27 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 PANTHER PTHR11649 12 482 2.1E-129 T 23-04-2016 DC74_RS10995 8208b15fe4ec017cdf93ae2ba0f0a507 490 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 399 477 5.7E-24 T 23-04-2016 IPR032859 GTPase Der, C-terminal KH-domain-like DC74_RS19620 c94e098ca0ece1aa1404209b7e305fcf 116 PANTHER PTHR41522 1 116 6.6E-53 T 23-04-2016 DC74_RS19620 c94e098ca0ece1aa1404209b7e305fcf 116 SUPERFAMILY SSF55486 2 115 5.74E-40 T 23-04-2016 DC74_RS19620 c94e098ca0ece1aa1404209b7e305fcf 116 Pfam PF06262 Zinicin-like metallopeptidase 28 114 1.5E-33 T 23-04-2016 IPR010428 Zinicin-like metallopeptidase DC74_RS24845 b68815bda87f0be05a56887f6d9a3da0 458 PIRSF PIRSF002746 13 458 1.4E-143 T 23-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 DC74_RS24845 b68815bda87f0be05a56887f6d9a3da0 458 PANTHER PTHR30354 15 458 1.4E-203 T 23-04-2016 DC74_RS24845 b68815bda87f0be05a56887f6d9a3da0 458 PANTHER PTHR30354:SF1 15 458 1.4E-203 T 23-04-2016 DC74_RS24845 b68815bda87f0be05a56887f6d9a3da0 458 Pfam PF02447 GntP family permease 20 457 3.0E-144 T 23-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 DC74_RS24845 b68815bda87f0be05a56887f6d9a3da0 458 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 20 458 5.3E-139 T 23-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 DC74_RS11575 b605d925bc29bcbb9fcec0c8b95c1e9d 171 Gene3D G3DSA:3.40.630.30 6 165 7.1E-65 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS11575 b605d925bc29bcbb9fcec0c8b95c1e9d 171 SUPERFAMILY SSF55729 2 128 9.43E-20 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS11575 b605d925bc29bcbb9fcec0c8b95c1e9d 171 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 7 164 4.6E-62 T 23-04-2016 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178|UniPathway: UPA00067 DC74_RS11575 b605d925bc29bcbb9fcec0c8b95c1e9d 171 Pfam PF00583 Acetyltransferase (GNAT) family 54 128 3.3E-11 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 SUPERFAMILY SSF48452 835 1013 1.9E-13 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 PRINTS PR00364 Disease resistance protein signature 493 507 1.2E-5 T 23-04-2016 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 PRINTS PR00364 Disease resistance protein signature 308 323 1.2E-5 T 23-04-2016 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 PRINTS PR00364 Disease resistance protein signature 397 411 1.2E-5 T 23-04-2016 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 Pfam PF03704 Bacterial transcriptional activator domain 95 237 5.5E-37 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 SMART SM00862 16 88 2.2E-10 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 Gene3D G3DSA:1.10.10.10 15 91 7.2E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 SUPERFAMILY SSF48452 91 258 4.17E-30 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 PANTHER PTHR35807 1 321 3.1E-46 T 23-04-2016 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 SMART SM01043 95 237 2.9E-44 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 SUPERFAMILY SSF46894 10 87 1.16E-9 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 83 9.4E-7 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 Gene3D G3DSA:1.25.40.10 693 713 1.1E-11 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 Gene3D G3DSA:1.25.40.10 101 213 1.1E-11 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 Gene3D G3DSA:1.25.40.10 828 1010 1.1E-11 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS13350 caf493dd49044e94ac0287d202cbe4d2 1153 SUPERFAMILY SSF52540 284 559 1.21E-17 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38685 5d8b5577f662e33d428684ad6d2725a6 606 Gene3D G3DSA:1.20.1560.10 18 346 1.0E-82 T 23-04-2016 DC74_RS38685 5d8b5577f662e33d428684ad6d2725a6 606 SMART SM00382 384 570 5.0E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS38685 5d8b5577f662e33d428684ad6d2725a6 606 Pfam PF00664 ABC transporter transmembrane region 32 313 2.5E-51 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS38685 5d8b5577f662e33d428684ad6d2725a6 606 PANTHER PTHR24221:SF271 17 603 2.9E-277 T 23-04-2016 DC74_RS38685 5d8b5577f662e33d428684ad6d2725a6 606 SUPERFAMILY SSF52540 354 592 4.35E-85 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38685 5d8b5577f662e33d428684ad6d2725a6 606 PANTHER PTHR24221 17 603 2.9E-277 T 23-04-2016 DC74_RS38685 5d8b5577f662e33d428684ad6d2725a6 606 Gene3D G3DSA:3.40.50.300 358 588 9.1E-76 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38685 5d8b5577f662e33d428684ad6d2725a6 606 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS38685 5d8b5577f662e33d428684ad6d2725a6 606 SUPERFAMILY SSF90123 14 346 1.83E-79 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS38685 5d8b5577f662e33d428684ad6d2725a6 606 Pfam PF00005 ABC transporter 376 524 2.7E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS26555 aef95e810d9f8697530f4b8a4edc0417 337 PANTHER PTHR30595 1 318 9.0E-39 T 23-04-2016 DC74_RS26555 aef95e810d9f8697530f4b8a4edc0417 337 SUPERFAMILY SSF46785 6 63 5.03E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26555 aef95e810d9f8697530f4b8a4edc0417 337 Pfam PF08279 HTH domain 7 62 6.6E-14 T 23-04-2016 IPR013196 Helix-turn-helix, type 11 DC74_RS26555 aef95e810d9f8697530f4b8a4edc0417 337 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 23-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 DC74_RS26555 aef95e810d9f8697530f4b8a4edc0417 337 Gene3D G3DSA:1.10.10.10 1 65 1.6E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26555 aef95e810d9f8697530f4b8a4edc0417 337 PANTHER PTHR30595:SF3 1 318 9.0E-39 T 23-04-2016 DC74_RS26555 aef95e810d9f8697530f4b8a4edc0417 337 Pfam PF13280 WYL domain 141 312 3.8E-29 T 23-04-2016 IPR026881 WYL domain DC74_RS12695 5dd203894f76c4bd6bc30cb4582da368 299 Hamap MF_00152 Probable endonuclease 4 [nfo]. 18 297 38.695 T 23-04-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 DC74_RS12695 5dd203894f76c4bd6bc30cb4582da368 299 SMART SM00518 19 297 6.3E-107 T 23-04-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 DC74_RS12695 5dd203894f76c4bd6bc30cb4582da368 299 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 232 248 - T 23-04-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 DC74_RS12695 5dd203894f76c4bd6bc30cb4582da368 299 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 192 199 - T 23-04-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 DC74_RS12695 5dd203894f76c4bd6bc30cb4582da368 299 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 83 91 - T 23-04-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 DC74_RS12695 5dd203894f76c4bd6bc30cb4582da368 299 Pfam PF01261 Xylose isomerase-like TIM barrel 36 256 3.7E-31 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS12695 5dd203894f76c4bd6bc30cb4582da368 299 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 20 294 3.7E-61 T 23-04-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 DC74_RS12695 5dd203894f76c4bd6bc30cb4582da368 299 PANTHER PTHR21445 4 299 2.8E-83 T 23-04-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 DC74_RS12695 5dd203894f76c4bd6bc30cb4582da368 299 SUPERFAMILY SSF51658 20 296 2.23E-73 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS12695 5dd203894f76c4bd6bc30cb4582da368 299 Gene3D G3DSA:3.20.20.150 19 297 7.9E-85 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 Gene3D G3DSA:1.10.287.130 165 235 1.3E-7 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 Pfam PF00512 His Kinase A (phospho-acceptor) domain 176 239 1.2E-7 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 Pfam PF00672 HAMP domain 102 171 1.8E-13 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 284 390 3.2E-18 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 SUPERFAMILY SSF158472 122 172 1.57E-6 T 23-04-2016 DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 SMART SM00304 121 174 4.4E-9 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 Gene3D G3DSA:3.30.565.10 244 392 1.6E-29 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 PANTHER PTHR24423 115 389 1.1E-52 T 23-04-2016 DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 PANTHER PTHR24423 13 20 1.1E-52 T 23-04-2016 DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 SUPERFAMILY SSF55874 243 389 1.31E-30 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 SMART SM00388 175 240 1.4E-8 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 SMART SM00387 284 392 7.1E-29 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 232 246 9.0E-7 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 389 9.0E-7 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 345 9.0E-7 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 370 9.0E-7 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS32245 c3814a7e1fe912f84b30ddafe4a91600 409 SUPERFAMILY SSF47384 158 238 7.26E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS22965 dd442d351d1c997626bfb0a6551515b0 361 PANTHER PTHR21666 247 343 2.6E-29 T 23-04-2016 DC74_RS22965 dd442d351d1c997626bfb0a6551515b0 361 PANTHER PTHR21666 36 45 2.6E-29 T 23-04-2016 DC74_RS22965 dd442d351d1c997626bfb0a6551515b0 361 Gene3D G3DSA:3.90.1720.10 239 345 5.7E-36 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS22965 dd442d351d1c997626bfb0a6551515b0 361 Pfam PF00877 NlpC/P60 family 256 340 1.5E-18 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS22965 dd442d351d1c997626bfb0a6551515b0 361 SUPERFAMILY SSF54001 241 354 6.38E-33 T 23-04-2016 DC74_RS24900 5e4ffdc9ab2b4249afe74e60c16ebb74 404 Pfam PF02348 Cytidylyltransferase 6 188 2.9E-22 T 23-04-2016 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 DC74_RS24900 5e4ffdc9ab2b4249afe74e60c16ebb74 404 PANTHER PTHR21485:SF3 2 400 3.5E-123 T 23-04-2016 DC74_RS24900 5e4ffdc9ab2b4249afe74e60c16ebb74 404 Pfam PF08282 haloacid dehalogenase-like hydrolase 327 386 3.5E-8 T 23-04-2016 IPR023214 HAD-like domain DC74_RS24900 5e4ffdc9ab2b4249afe74e60c16ebb74 404 Gene3D G3DSA:3.40.50.1000 246 398 7.5E-33 T 23-04-2016 IPR023214 HAD-like domain DC74_RS24900 5e4ffdc9ab2b4249afe74e60c16ebb74 404 Gene3D G3DSA:3.90.550.10 4 235 1.3E-71 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS24900 5e4ffdc9ab2b4249afe74e60c16ebb74 404 SUPERFAMILY SSF53448 3 235 7.1E-49 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS24900 5e4ffdc9ab2b4249afe74e60c16ebb74 404 SUPERFAMILY SSF56784 252 400 3.16E-31 T 23-04-2016 IPR023214 HAD-like domain DC74_RS24900 5e4ffdc9ab2b4249afe74e60c16ebb74 404 PANTHER PTHR21485 2 400 3.5E-123 T 23-04-2016 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 Pfam PF02803 Thiolase, C-terminal domain 280 402 7.4E-38 T 23-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 SUPERFAMILY SSF53901 280 402 1.15E-34 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 ProSitePatterns PS00099 Thiolases active site. 384 397 - T 23-04-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 PIRSF PIRSF000429 8 402 2.4E-127 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 PANTHER PTHR18919:SF91 8 402 1.4E-202 T 23-04-2016 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 SUPERFAMILY SSF53901 12 278 1.29E-75 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 Pfam PF00108 Thiolase, N-terminal domain 13 271 2.6E-71 T 23-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 95 113 - T 23-04-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 ProSitePatterns PS00737 Thiolases signature 2. 349 365 - T 23-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 Gene3D G3DSA:3.40.47.10 286 401 1.0E-48 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 Gene3D G3DSA:3.40.47.10 166 208 1.0E-48 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 Gene3D G3DSA:3.40.47.10 12 134 3.4E-65 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 Gene3D G3DSA:3.40.47.10 209 285 3.4E-65 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 PANTHER PTHR18919 8 402 1.4E-202 T 23-04-2016 DC74_RS29805 02abe33d53495b06862e2f884ed178b8 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 16 401 8.6E-131 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SMART SM00320 100 142 9.9E-7 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SMART SM00320 216 260 5.2E-4 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SMART SM00320 396 442 27.0 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SMART SM00320 527 568 0.11 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SMART SM00320 575 613 2.0 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SMART SM00320 358 393 8.2 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SMART SM00320 263 304 15.0 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SMART SM00320 12 53 0.8 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SMART SM00320 145 192 0.62 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SMART SM00320 616 657 6.8E-10 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SMART SM00320 307 351 0.0076 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SMART SM00320 56 97 0.011 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SUPERFAMILY SSF50978 26 351 1.59E-56 T 23-04-2016 IPR017986 WD40-repeat-containing domain GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 PANTHER PTHR22847 245 454 5.2E-58 T 23-04-2016 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 PANTHER PTHR22847 476 501 5.2E-58 T 23-04-2016 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 PANTHER PTHR22847 518 687 5.2E-58 T 23-04-2016 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 PANTHER PTHR22847 38 219 5.2E-58 T 23-04-2016 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SUPERFAMILY SSF50998 246 322 1.1E-53 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 SUPERFAMILY SSF50998 367 674 1.1E-53 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 Gene3D G3DSA:2.130.10.10 13 218 3.5E-36 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 Gene3D G3DSA:2.130.10.10 495 688 3.0E-35 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 PRINTS PR00320 G protein beta WD-40 repeat signature 179 193 1.1E-8 T 23-04-2016 IPR020472 G-protein beta WD-40 repeat DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 PRINTS PR00320 G protein beta WD-40 repeat signature 644 658 1.1E-8 T 23-04-2016 IPR020472 G-protein beta WD-40 repeat DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 PRINTS PR00320 G protein beta WD-40 repeat signature 129 143 1.1E-8 T 23-04-2016 IPR020472 G-protein beta WD-40 repeat DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 Pfam PF00400 WD domain, G-beta repeat 619 657 7.7E-7 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 Pfam PF00400 WD domain, G-beta repeat 226 260 7.1E-4 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 Pfam PF00400 WD domain, G-beta repeat 177 192 0.0079 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 Pfam PF00400 WD domain, G-beta repeat 103 142 6.4E-6 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 Pfam PF00400 WD domain, G-beta repeat 308 351 1.5E-6 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 Gene3D G3DSA:2.130.10.10 227 494 7.3E-37 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 247 261 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 380 394 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 179 193 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS39810 6d5f21059a10f205ccada1a5075a31c7 698 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 644 658 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS22460 f3701b2091f9b8233626f2f15a7ca27e 302 Gene3D G3DSA:3.20.20.20 8 276 4.9E-105 T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 DC74_RS22460 f3701b2091f9b8233626f2f15a7ca27e 302 Pfam PF00809 Pterin binding enzyme 13 259 1.8E-82 T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 DC74_RS22460 f3701b2091f9b8233626f2f15a7ca27e 302 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 12 27 - T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 DC74_RS22460 f3701b2091f9b8233626f2f15a7ca27e 302 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 46 59 - T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 DC74_RS22460 f3701b2091f9b8233626f2f15a7ca27e 302 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 12 273 2.5E-90 T 23-04-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614|UniPathway: UPA00077 DC74_RS22460 f3701b2091f9b8233626f2f15a7ca27e 302 PANTHER PTHR20941:SF1 4 279 5.7E-110 T 23-04-2016 DC74_RS22460 f3701b2091f9b8233626f2f15a7ca27e 302 PANTHER PTHR20941 4 279 5.7E-110 T 23-04-2016 DC74_RS22460 f3701b2091f9b8233626f2f15a7ca27e 302 SUPERFAMILY SSF51717 10 274 3.4E-91 T 23-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 DC74_RS05265 56f7f47cb9f677d434ba9dfa63811f36 294 SUPERFAMILY SSF159713 97 266 2.22E-13 T 23-04-2016 DC74_RS05265 56f7f47cb9f677d434ba9dfa63811f36 294 Pfam PF04016 Putative heavy-metal chelation 156 266 1.5E-6 T 23-04-2016 IPR007161 Putative heavy-metal chelation domain DC74_RS07890 6ee162bc73cbe30e2435a2b4f24f5ba0 327 PANTHER PTHR12304:SF4 6 320 2.1E-92 T 23-04-2016 DC74_RS07890 6ee162bc73cbe30e2435a2b4f24f5ba0 327 PANTHER PTHR12304 6 320 2.1E-92 T 23-04-2016 IPR023186 Inosine/uridine-preferring nucleoside hydrolase DC74_RS07890 6ee162bc73cbe30e2435a2b4f24f5ba0 327 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 7 303 1.2E-66 T 23-04-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DC74_RS07890 6ee162bc73cbe30e2435a2b4f24f5ba0 327 SUPERFAMILY SSF53590 6 308 3.01E-87 T 23-04-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DC74_RS07890 6ee162bc73cbe30e2435a2b4f24f5ba0 327 Gene3D G3DSA:3.90.245.10 6 320 3.4E-96 T 23-04-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DC74_RS07890 6ee162bc73cbe30e2435a2b4f24f5ba0 327 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 12 22 - T 23-04-2016 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 DC74_RS02560 738b64d0a7599d43949380d32fa47e18 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 7.3E-20 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS02560 738b64d0a7599d43949380d32fa47e18 307 Gene3D G3DSA:3.40.190.10 173 255 4.4E-8 T 23-04-2016 DC74_RS02560 738b64d0a7599d43949380d32fa47e18 307 SUPERFAMILY SSF46785 3 101 3.08E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02560 738b64d0a7599d43949380d32fa47e18 307 Pfam PF03466 LysR substrate binding domain 93 284 8.4E-24 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS02560 738b64d0a7599d43949380d32fa47e18 307 Gene3D G3DSA:3.40.190.10 93 172 6.4E-13 T 23-04-2016 DC74_RS02560 738b64d0a7599d43949380d32fa47e18 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.7E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS02560 738b64d0a7599d43949380d32fa47e18 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.7E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS02560 738b64d0a7599d43949380d32fa47e18 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.7E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS02560 738b64d0a7599d43949380d32fa47e18 307 Gene3D G3DSA:1.10.10.10 1 82 2.7E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02560 738b64d0a7599d43949380d32fa47e18 307 PANTHER PTHR30346 1 298 3.4E-55 T 23-04-2016 DC74_RS02560 738b64d0a7599d43949380d32fa47e18 307 SUPERFAMILY SSF53850 92 288 8.38E-22 T 23-04-2016 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 211 4.3E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 211 223 4.3E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 195 4.3E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 SUPERFAMILY SSF46894 177 240 2.28E-18 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 Pfam PF00196 Bacterial regulatory proteins, luxR family 180 235 1.3E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 ProSitePatterns PS00622 LuxR-type HTH domain signature. 195 222 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 Gene3D G3DSA:3.40.50.2300 27 144 1.8E-32 T 23-04-2016 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 SMART SM00421 178 235 8.6E-19 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 SUPERFAMILY SSF52172 28 148 1.04E-30 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 PANTHER PTHR26402:SF564 29 242 5.8E-73 T 23-04-2016 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 Pfam PF00072 Response regulator receiver domain 31 144 8.2E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 SMART SM00448 29 143 1.2E-29 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 PANTHER PTHR26402 29 242 5.8E-73 T 23-04-2016 DC74_RS01660 daa6a7241e6ba16b85458f35c5fa60f9 272 Gene3D G3DSA:1.10.10.10 145 241 4.5E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14050 67f3ce358e51a6f6ca998b8e71fdf264 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 173 289 1.3E-17 T 23-04-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 DC74_RS14050 67f3ce358e51a6f6ca998b8e71fdf264 296 Gene3D G3DSA:1.10.1040.10 173 289 1.5E-28 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS14050 67f3ce358e51a6f6ca998b8e71fdf264 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 12 167 1.8E-35 T 23-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 DC74_RS14050 67f3ce358e51a6f6ca998b8e71fdf264 296 PANTHER PTHR22981 11 290 6.4E-70 T 23-04-2016 DC74_RS14050 67f3ce358e51a6f6ca998b8e71fdf264 296 Gene3D G3DSA:3.40.50.720 5 172 2.5E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS14050 67f3ce358e51a6f6ca998b8e71fdf264 296 SUPERFAMILY SSF48179 173 290 4.08E-25 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS14050 67f3ce358e51a6f6ca998b8e71fdf264 296 PIRSF PIRSF000103 4 295 2.5E-74 T 23-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 DC74_RS14050 67f3ce358e51a6f6ca998b8e71fdf264 296 SUPERFAMILY SSF51735 11 168 9.27E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS34290 14c5c56a3500a4a5770332caa7f58af1 424 PIRSF PIRSF003085 33 422 6.9E-118 T 23-04-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 DC74_RS34290 14c5c56a3500a4a5770332caa7f58af1 424 Pfam PF02353 Mycolic acid cyclopropane synthetase 139 409 3.0E-86 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS34290 14c5c56a3500a4a5770332caa7f58af1 424 SUPERFAMILY SSF53335 146 412 2.19E-69 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS34290 14c5c56a3500a4a5770332caa7f58af1 424 PANTHER PTHR10108 347 412 7.4E-110 T 23-04-2016 DC74_RS34290 14c5c56a3500a4a5770332caa7f58af1 424 PANTHER PTHR10108 71 328 7.4E-110 T 23-04-2016 DC74_RS34290 14c5c56a3500a4a5770332caa7f58af1 424 Gene3D G3DSA:3.40.50.150 134 412 7.0E-95 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS34290 14c5c56a3500a4a5770332caa7f58af1 424 PANTHER PTHR10108:SF795 347 412 7.4E-110 T 23-04-2016 DC74_RS34290 14c5c56a3500a4a5770332caa7f58af1 424 PANTHER PTHR10108:SF795 71 328 7.4E-110 T 23-04-2016 DC74_RS29730 0cd55a7c432f349695dbd05e60995651 399 ProSitePatterns PS01125 ROK family signature. 215 242 - T 23-04-2016 IPR000600 ROK family DC74_RS29730 0cd55a7c432f349695dbd05e60995651 399 SUPERFAMILY SSF53067 79 383 2.73E-59 T 23-04-2016 DC74_RS29730 0cd55a7c432f349695dbd05e60995651 399 SUPERFAMILY SSF46785 12 71 2.03E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29730 0cd55a7c432f349695dbd05e60995651 399 Gene3D G3DSA:3.30.420.40 77 219 1.6E-42 T 23-04-2016 DC74_RS29730 0cd55a7c432f349695dbd05e60995651 399 PANTHER PTHR18964 58 388 1.7E-113 T 23-04-2016 DC74_RS29730 0cd55a7c432f349695dbd05e60995651 399 Gene3D G3DSA:3.30.420.40 220 361 1.3E-49 T 23-04-2016 DC74_RS29730 0cd55a7c432f349695dbd05e60995651 399 Gene3D G3DSA:1.10.10.10 10 74 1.0E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29730 0cd55a7c432f349695dbd05e60995651 399 Pfam PF00480 ROK family 82 378 5.1E-59 T 23-04-2016 IPR000600 ROK family DC74_RS29730 0cd55a7c432f349695dbd05e60995651 399 PANTHER PTHR18964:SF123 58 388 1.7E-113 T 23-04-2016 DC74_RS29730 0cd55a7c432f349695dbd05e60995651 399 Pfam PF12802 MarR family 17 68 2.4E-8 T 23-04-2016 DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 PANTHER PTHR11935:SF9 2 102 1.2E-70 T 23-04-2016 DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 PANTHER PTHR11935 134 274 1.2E-70 T 23-04-2016 DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 Gene3D G3DSA:3.60.15.10 131 276 1.1E-49 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 Gene3D G3DSA:3.60.15.10 10 99 1.1E-49 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 Pfam PF00753 Metallo-beta-lactamase superfamily 10 216 8.4E-12 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 PANTHER PTHR11935 2 102 1.2E-70 T 23-04-2016 DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 Gene3D G3DSA:3.40.250.10 381 481 1.2E-24 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 SUPERFAMILY SSF56281 117 258 5.28E-36 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 SUPERFAMILY SSF56281 12 87 5.28E-36 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 PANTHER PTHR11935:SF9 134 274 1.2E-70 T 23-04-2016 DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 SUPERFAMILY SSF52821 257 369 8.51E-13 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 SMART SM00849 12 216 1.5E-19 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 Gene3D G3DSA:3.40.250.10 289 369 2.5E-6 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 SMART SM00450 289 385 3.3 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 SMART SM00450 396 485 6.2E-20 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 SUPERFAMILY SSF52821 376 481 6.68E-27 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 Pfam PF00581 Rhodanese-like domain 293 369 8.1E-6 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS17895 652d279af0f8e5b0b31f28d88a58863a 488 Pfam PF00581 Rhodanese-like domain 409 481 2.1E-13 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS07655 c9145c8249839ea659a231bb10d6f97e 222 SUPERFAMILY SSF53474 2 219 9.85E-24 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS07655 c9145c8249839ea659a231bb10d6f97e 222 Gene3D G3DSA:3.40.50.1820 1 220 8.6E-41 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS07655 c9145c8249839ea659a231bb10d6f97e 222 PANTHER PTHR10992:SF810 1 221 6.9E-93 T 23-04-2016 DC74_RS07655 c9145c8249839ea659a231bb10d6f97e 222 Pfam PF12697 Alpha/beta hydrolase family 3 214 2.4E-12 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS07655 c9145c8249839ea659a231bb10d6f97e 222 PANTHER PTHR10992 1 221 6.9E-93 T 23-04-2016 DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 3.7E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 3.7E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 3.7E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 PANTHER PTHR24322 20 152 4.8E-47 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 PANTHER PTHR24322 168 204 4.8E-47 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 255 9.4E-63 T 23-04-2016 DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 Gene3D G3DSA:3.40.50.720 12 255 4.9E-75 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 SUPERFAMILY SSF51735 14 256 3.5E-72 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 5.4E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 5.4E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 5.4E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 5.4E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 5.4E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36340 7601a3cba86d107af1d5ca4ab408e475 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 5.4E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS29425 263db5a7a5a1e787233349e4b3a55198 263 PANTHER PTHR11941:SF54 1 260 2.5E-116 T 23-04-2016 DC74_RS29425 263db5a7a5a1e787233349e4b3a55198 263 Gene3D G3DSA:3.90.226.10 8 203 1.2E-73 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS29425 263db5a7a5a1e787233349e4b3a55198 263 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 104 124 - T 23-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 DC74_RS29425 263db5a7a5a1e787233349e4b3a55198 263 PANTHER PTHR11941 1 260 2.5E-116 T 23-04-2016 DC74_RS29425 263db5a7a5a1e787233349e4b3a55198 263 SUPERFAMILY SSF52096 7 262 6.12E-87 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS29425 263db5a7a5a1e787233349e4b3a55198 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 261 8.3E-76 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS29425 263db5a7a5a1e787233349e4b3a55198 263 Gene3D G3DSA:1.10.12.10 210 262 5.0E-22 T 23-04-2016 IPR014748 Crontonase, C-terminal DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 SUPERFAMILY SSF69118 299 418 1.11E-35 T 23-04-2016 IPR029032 AhpD-like DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 1.8E-10 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 PRINTS PR00111 Alpha/beta hydrolase fold signature 198 212 1.8E-10 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 PRINTS PR00111 Alpha/beta hydrolase fold signature 42 57 1.8E-10 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 1.8E-10 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 Pfam PF02627 Carboxymuconolactone decarboxylase family 330 412 2.6E-25 T 23-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 Gene3D G3DSA:3.40.50.1820 5 253 6.5E-56 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 Gene3D G3DSA:1.20.1290.10 301 419 7.2E-29 T 23-04-2016 IPR029032 AhpD-like DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 SUPERFAMILY SSF53474 5 252 4.55E-58 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 PANTHER PTHR10992 1 254 2.3E-57 T 23-04-2016 DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 300 417 7.3E-50 T 23-04-2016 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44|UniPathway: UPA00157 DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 Pfam PF00561 alpha/beta hydrolase fold 17 126 1.5E-16 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS31525 ea3a1653c176314d44c7b8cca71680bf 423 PANTHER PTHR10992:SF818 1 254 2.3E-57 T 23-04-2016 DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 SMART SM01240 19 482 6.1E-189 T 23-04-2016 DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 15 483 1.4E-270 T 23-04-2016 IPR005991 IMP dehydrogenase-related 1 KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 21 481 3.9E-101 T 23-04-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 Pfam PF00571 CBS domain 107 150 7.2E-5 T 23-04-2016 IPR000644 CBS domain DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 Pfam PF00571 CBS domain 157 210 8.1E-8 T 23-04-2016 IPR000644 CBS domain DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 Gene3D G3DSA:3.20.20.70 18 482 4.1E-133 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 PIRSF PIRSF000130 10 487 1.4E-145 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 PANTHER PTHR11911 305 482 9.9E-297 T 23-04-2016 DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 PANTHER PTHR11911 2 287 9.9E-297 T 23-04-2016 DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 PANTHER PTHR11911:SF80 305 482 9.9E-297 T 23-04-2016 DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 PANTHER PTHR11911:SF80 2 287 9.9E-297 T 23-04-2016 DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 SUPERFAMILY SSF51412 210 481 6.67E-89 T 23-04-2016 DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 SUPERFAMILY SSF51412 16 101 6.67E-89 T 23-04-2016 DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 SMART SM00116 106 153 0.082 T 23-04-2016 IPR000644 CBS domain DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 SMART SM00116 164 212 0.23 T 23-04-2016 IPR000644 CBS domain DC74_RS09325 750817612cdc769e54f2765e9edf8d5f 487 SUPERFAMILY SSF54631 104 211 8.09E-20 T 23-04-2016 DC74_RS36185 0557d95ad6d2c088f200b7c9fbf32cf0 105 Gene3D G3DSA:1.10.287.1060 3 97 7.7E-5 T 23-04-2016 DC74_RS36185 0557d95ad6d2c088f200b7c9fbf32cf0 105 SUPERFAMILY SSF140453 3 95 3.92E-6 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS36185 0557d95ad6d2c088f200b7c9fbf32cf0 105 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 3 95 1.1E-6 T 23-04-2016 IPR022536 ESX-1 secretion-associated protein EspC DC74_RS14420 2724bbf146198ce80c65fb5304da16bf 137 PANTHER PTHR22769 12 118 6.9E-23 T 23-04-2016 DC74_RS14420 2724bbf146198ce80c65fb5304da16bf 137 SUPERFAMILY SSF55811 9 129 2.17E-29 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS14420 2724bbf146198ce80c65fb5304da16bf 137 PRINTS PR00502 NUDIX hydrolase family signature 37 51 1.3E-8 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS14420 2724bbf146198ce80c65fb5304da16bf 137 PRINTS PR00502 NUDIX hydrolase family signature 51 66 1.3E-8 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS14420 2724bbf146198ce80c65fb5304da16bf 137 Gene3D G3DSA:3.90.79.10 10 133 1.2E-30 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS14420 2724bbf146198ce80c65fb5304da16bf 137 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS14420 2724bbf146198ce80c65fb5304da16bf 137 Pfam PF00293 NUDIX domain 12 115 1.2E-20 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 Gene3D G3DSA:1.20.140.10 283 439 2.8E-17 T 23-04-2016 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 Gene3D G3DSA:1.20.140.10 475 587 2.6E-11 T 23-04-2016 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 Pfam PF01756 Acyl-CoA oxidase 492 589 1.3E-4 T 23-04-2016 IPR002655 Acyl-CoA oxidase, C-terminal GO:0003997|GO:0005777|GO:0006635|GO:0055114 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7726 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 SUPERFAMILY SSF47203 466 602 2.62E-12 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 SUPERFAMILY SSF47203 282 441 5.96E-14 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 PANTHER PTHR10909:SF11 261 346 1.7E-21 T 23-04-2016 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 PANTHER PTHR10909:SF11 371 439 1.7E-21 T 23-04-2016 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 PANTHER PTHR10909:SF11 23 244 1.7E-21 T 23-04-2016 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 PANTHER PTHR10909 261 346 1.7E-21 T 23-04-2016 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 PANTHER PTHR10909 371 439 1.7E-21 T 23-04-2016 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 PANTHER PTHR10909 23 244 1.7E-21 T 23-04-2016 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 Gene3D G3DSA:2.40.110.10 126 252 3.7E-19 T 23-04-2016 DC74_RS03005 2b533b77a152b87971402a6836756fd6 614 SUPERFAMILY SSF56645 8 244 5.1E-25 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS17515 4f637039b482884ab1352d8e6d497149 340 PRINTS PR00075 Fatty acid desaturase family 1 signature 272 286 2.4E-15 T 23-04-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 DC74_RS17515 4f637039b482884ab1352d8e6d497149 340 PRINTS PR00075 Fatty acid desaturase family 1 signature 69 91 2.4E-15 T 23-04-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 DC74_RS17515 4f637039b482884ab1352d8e6d497149 340 PRINTS PR00075 Fatty acid desaturase family 1 signature 92 112 2.4E-15 T 23-04-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 DC74_RS17515 4f637039b482884ab1352d8e6d497149 340 PRINTS PR00075 Fatty acid desaturase family 1 signature 229 250 2.4E-15 T 23-04-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 DC74_RS17515 4f637039b482884ab1352d8e6d497149 340 PANTHER PTHR11351:SF3 12 327 3.9E-157 T 23-04-2016 DC74_RS17515 4f637039b482884ab1352d8e6d497149 340 Pfam PF00487 Fatty acid desaturase 70 284 2.9E-20 T 23-04-2016 IPR005804 Fatty acid desaturase domain GO:0006629 DC74_RS17515 4f637039b482884ab1352d8e6d497149 340 PANTHER PTHR11351 12 327 3.9E-157 T 23-04-2016 DC74_RS37800 8ed571d4e786ce5f09aea092fc2ad933 75 SUPERFAMILY SSF50118 1 73 2.94E-18 T 23-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor DC74_RS37800 8ed571d4e786ce5f09aea092fc2ad933 75 Pfam PF08940 Domain of unknown function (DUF1918) 1 56 4.9E-21 T 23-04-2016 IPR015035 Domain of unknown function DUF1918 DC74_RS34065 6d9f433029f049a9264a88848169053d 266 Pfam PF02754 Cysteine-rich domain 138 222 1.1E-14 T 23-04-2016 IPR004017 Cysteine-rich domain DC74_RS34065 6d9f433029f049a9264a88848169053d 266 Pfam PF02754 Cysteine-rich domain 3 83 2.5E-13 T 23-04-2016 IPR004017 Cysteine-rich domain DC74_RS34065 6d9f433029f049a9264a88848169053d 266 PANTHER PTHR30296:SF0 2 251 1.8E-118 T 23-04-2016 DC74_RS34065 6d9f433029f049a9264a88848169053d 266 PANTHER PTHR30296 2 251 1.8E-118 T 23-04-2016 DC74_RS01220 72bebe45a2d1a738616bd8870e26ce9d 275 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 15 239 2.3E-108 T 23-04-2016 IPR022488 Polyphosphate kinase-2-related DC74_RS01220 72bebe45a2d1a738616bd8870e26ce9d 275 PANTHER PTHR34383:SF1 1 270 8.3E-175 T 23-04-2016 DC74_RS01220 72bebe45a2d1a738616bd8870e26ce9d 275 PANTHER PTHR34383 1 270 8.3E-175 T 23-04-2016 DC74_RS01220 72bebe45a2d1a738616bd8870e26ce9d 275 SUPERFAMILY SSF52540 46 234 3.13E-32 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS01220 72bebe45a2d1a738616bd8870e26ce9d 275 PIRSF PIRSF028756 1 270 8.8E-129 T 23-04-2016 IPR016898 Polyphosphate kinase 2 DC74_RS01220 72bebe45a2d1a738616bd8870e26ce9d 275 Gene3D G3DSA:3.40.50.300 13 247 1.9E-105 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS01220 72bebe45a2d1a738616bd8870e26ce9d 275 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 15 239 3.3E-116 T 23-04-2016 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 DC74_RS00530 9993895ee85613f4f70c3253514dc0f9 180 Gene3D G3DSA:3.40.630.30 1 175 4.2E-52 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS00530 9993895ee85613f4f70c3253514dc0f9 180 Pfam PF13302 Acetyltransferase (GNAT) domain 8 151 3.7E-33 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS00530 9993895ee85613f4f70c3253514dc0f9 180 SUPERFAMILY SSF55729 1 155 7.15E-41 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS00530 9993895ee85613f4f70c3253514dc0f9 180 PANTHER PTHR13256:SF19 3 151 6.3E-47 T 23-04-2016 DC74_RS00530 9993895ee85613f4f70c3253514dc0f9 180 PANTHER PTHR13256 3 151 6.3E-47 T 23-04-2016 DC74_RS17935 a224d6a3d3a63fd88c5dc409e94f4a47 271 PANTHER PTHR38589:SF1 18 271 1.4E-33 T 23-04-2016 DC74_RS17935 a224d6a3d3a63fd88c5dc409e94f4a47 271 PANTHER PTHR38589 18 271 1.4E-33 T 23-04-2016 DC74_RS17935 a224d6a3d3a63fd88c5dc409e94f4a47 271 Pfam PF03734 L,D-transpeptidase catalytic domain 136 265 4.1E-5 T 23-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 SUPERFAMILY SSF55785 133 247 1.38E-12 T 23-04-2016 IPR000014 PAS domain DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 SUPERFAMILY SSF55781 256 317 1.42E-13 T 23-04-2016 IPR029016 GAF domain-like DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 SUPERFAMILY SSF55781 346 438 1.42E-13 T 23-04-2016 IPR029016 GAF domain-like DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 SUPERFAMILY SSF55785 9 117 1.7E-10 T 23-04-2016 IPR000014 PAS domain DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 PANTHER PTHR21021 385 539 1.9E-56 T 23-04-2016 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 PANTHER PTHR21021 573 714 1.9E-56 T 23-04-2016 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 SMART SM00091 128 194 9.9E-4 T 23-04-2016 IPR000014 PAS domain DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 SMART SM00091 5 72 3.5E-6 T 23-04-2016 IPR000014 PAS domain DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 SMART SM00065 273 441 3.0E-5 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 Gene3D G3DSA:3.30.450.40 261 439 1.7E-38 T 23-04-2016 IPR029016 GAF domain-like DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 Pfam PF08448 PAS fold 17 121 3.5E-7 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 Pfam PF08448 PAS fold 135 246 2.2E-21 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 Pfam PF13185 GAF domain 272 432 4.1E-8 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 SMART SM00331 459 705 8.1E-42 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 132 250 1.9E-6 T 23-04-2016 IPR000014 PAS domain DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 121 5.7E-7 T 23-04-2016 IPR000014 PAS domain DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 Pfam PF13581 Histidine kinase-like ATPase domain 719 825 3.5E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 SUPERFAMILY SSF55874 742 827 5.75E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 Gene3D G3DSA:3.30.450.20 9 117 3.2E-14 T 23-04-2016 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 Gene3D G3DSA:3.30.450.20 127 244 8.0E-15 T 23-04-2016 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 PANTHER PTHR21021:SF19 385 539 1.9E-56 T 23-04-2016 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 PANTHER PTHR21021:SF19 573 714 1.9E-56 T 23-04-2016 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 488 705 9.3E-50 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 SUPERFAMILY SSF81606 475 529 2.88E-7 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS25770 dd7a7247ca396f1872cb08c1744e66ab 849 SUPERFAMILY SSF81606 567 706 2.88E-7 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS14410 f3f3b8052ebdff7eda9198f0971e723b 169 SUPERFAMILY SSF54919 8 168 5.37E-40 T 23-04-2016 DC74_RS14410 f3f3b8052ebdff7eda9198f0971e723b 169 Pfam PF00334 Nucleoside diphosphate kinase 10 156 1.5E-38 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS14410 f3f3b8052ebdff7eda9198f0971e723b 169 Gene3D G3DSA:3.30.70.141 8 167 8.3E-43 T 23-04-2016 DC74_RS14410 f3f3b8052ebdff7eda9198f0971e723b 169 SMART SM00562 9 159 1.4E-39 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS14410 f3f3b8052ebdff7eda9198f0971e723b 169 PRINTS PR01243 Nucleoside diphosphate kinase signature 79 96 1.3E-22 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS14410 f3f3b8052ebdff7eda9198f0971e723b 169 PRINTS PR01243 Nucleoside diphosphate kinase signature 100 116 1.3E-22 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS14410 f3f3b8052ebdff7eda9198f0971e723b 169 PRINTS PR01243 Nucleoside diphosphate kinase signature 12 34 1.3E-22 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS14410 f3f3b8052ebdff7eda9198f0971e723b 169 PANTHER PTHR11349 6 169 8.3E-37 T 23-04-2016 DC74_RS07975 f96cf575dccbb99d78bc3af222f27d2c 340 PANTHER PTHR12715 52 340 1.7E-102 T 23-04-2016 DC74_RS07975 f96cf575dccbb99d78bc3af222f27d2c 340 Pfam PF00892 EamA-like transporter family 197 332 4.2E-17 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS07975 f96cf575dccbb99d78bc3af222f27d2c 340 Pfam PF00892 EamA-like transporter family 58 185 1.6E-19 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS07975 f96cf575dccbb99d78bc3af222f27d2c 340 PANTHER PTHR12715:SF17 52 340 1.7E-102 T 23-04-2016 DC74_RS07975 f96cf575dccbb99d78bc3af222f27d2c 340 SUPERFAMILY SSF103481 238 335 3.14E-12 T 23-04-2016 DC74_RS07975 f96cf575dccbb99d78bc3af222f27d2c 340 SUPERFAMILY SSF103481 86 186 1.18E-12 T 23-04-2016 DC74_RS02855 019d5d981c4b0d22e74eff594e97ecf0 408 Gene3D G3DSA:1.20.1250.20 197 383 6.3E-13 T 23-04-2016 DC74_RS02855 019d5d981c4b0d22e74eff594e97ecf0 408 Pfam PF07690 Major Facilitator Superfamily 8 328 9.2E-40 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS02855 019d5d981c4b0d22e74eff594e97ecf0 408 Gene3D G3DSA:1.20.1250.20 5 183 6.1E-26 T 23-04-2016 DC74_RS02855 019d5d981c4b0d22e74eff594e97ecf0 408 SUPERFAMILY SSF103473 3 382 1.11E-57 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS02855 019d5d981c4b0d22e74eff594e97ecf0 408 PANTHER PTHR23501 1 381 3.9E-158 T 23-04-2016 DC74_RS02855 019d5d981c4b0d22e74eff594e97ecf0 408 PANTHER PTHR23501:SF4 1 381 3.9E-158 T 23-04-2016 DC74_RS35930 9115abec53411a096b77967c5077b766 246 Gene3D G3DSA:1.10.357.10 91 241 7.6E-34 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS35930 9115abec53411a096b77967c5077b766 246 PANTHER PTHR30055 14 246 8.7E-28 T 23-04-2016 DC74_RS35930 9115abec53411a096b77967c5077b766 246 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 78 1.0E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS35930 9115abec53411a096b77967c5077b766 246 Gene3D G3DSA:1.10.10.60 18 88 1.1E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS35930 9115abec53411a096b77967c5077b766 246 PANTHER PTHR30055:SF93 14 246 8.7E-28 T 23-04-2016 DC74_RS35930 9115abec53411a096b77967c5077b766 246 SUPERFAMILY SSF48498 95 242 4.71E-26 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS35930 9115abec53411a096b77967c5077b766 246 SUPERFAMILY SSF46689 22 88 1.18E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS35930 9115abec53411a096b77967c5077b766 246 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 92 239 5.6E-21 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS40550 5841cefedfa3b706857de27d2cee3aaf 171 Gene3D G3DSA:1.20.1250.20 3 139 6.2E-16 T 23-04-2016 DC74_RS40550 5841cefedfa3b706857de27d2cee3aaf 171 PANTHER PTHR23501 2 139 1.6E-20 T 23-04-2016 DC74_RS40550 5841cefedfa3b706857de27d2cee3aaf 171 Pfam PF07690 Major Facilitator Superfamily 2 130 2.9E-13 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS40550 5841cefedfa3b706857de27d2cee3aaf 171 SUPERFAMILY SSF103473 2 139 9.42E-20 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21210 f904f2d291d3de6173f351cf042bc3c5 158 PANTHER PTHR35526 16 155 1.5E-16 T 23-04-2016 DC74_RS21210 f904f2d291d3de6173f351cf042bc3c5 158 Gene3D G3DSA:3.30.565.10 29 142 5.8E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21210 f904f2d291d3de6173f351cf042bc3c5 158 SUPERFAMILY SSF55874 31 135 1.31E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21210 f904f2d291d3de6173f351cf042bc3c5 158 Pfam PF13581 Histidine kinase-like ATPase domain 12 139 2.5E-24 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS38540 6a031cc99af2f5dc09d1e9910a39e0bf 573 PANTHER PTHR10909 1 414 3.7E-191 T 23-04-2016 DC74_RS38540 6a031cc99af2f5dc09d1e9910a39e0bf 573 PANTHER PTHR10909:SF207 1 414 3.7E-191 T 23-04-2016 DC74_RS38540 6a031cc99af2f5dc09d1e9910a39e0bf 573 Gene3D G3DSA:1.20.140.10 232 394 3.5E-22 T 23-04-2016 DC74_RS38540 6a031cc99af2f5dc09d1e9910a39e0bf 573 Gene3D G3DSA:2.40.110.10 136 231 1.2E-10 T 23-04-2016 DC74_RS38540 6a031cc99af2f5dc09d1e9910a39e0bf 573 SUPERFAMILY SSF56645 16 239 6.94E-24 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS38540 6a031cc99af2f5dc09d1e9910a39e0bf 573 SUPERFAMILY SSF47203 244 399 3.54E-26 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS38540 6a031cc99af2f5dc09d1e9910a39e0bf 573 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 393 2.8E-18 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS02745 9767ec6fcb6eaedd36a797fbe405f360 305 PANTHER PTHR20883 9 262 6.2E-26 T 23-04-2016 DC74_RS02745 9767ec6fcb6eaedd36a797fbe405f360 305 Gene3D G3DSA:2.60.120.620 13 264 8.3E-48 T 23-04-2016 DC74_RS02745 9767ec6fcb6eaedd36a797fbe405f360 305 SUPERFAMILY SSF51197 18 264 1.65E-47 T 23-04-2016 DC74_RS02745 9767ec6fcb6eaedd36a797fbe405f360 305 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 27 250 5.7E-20 T 23-04-2016 IPR008775 Phytanoyl-CoA dioxygenase DC74_RS22335 ec9a67eab14a2bbf1e459983c0b35b5e 78 Gene3D G3DSA:4.10.640.10 15 76 3.3E-29 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22335 ec9a67eab14a2bbf1e459983c0b35b5e 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 4 78 20.546 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22335 ec9a67eab14a2bbf1e459983c0b35b5e 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 75 3.0E-12 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22335 ec9a67eab14a2bbf1e459983c0b35b5e 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 23-04-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22335 ec9a67eab14a2bbf1e459983c0b35b5e 78 Pfam PF01084 Ribosomal protein S18 23 73 1.1E-24 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22335 ec9a67eab14a2bbf1e459983c0b35b5e 78 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 1.1E-17 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22335 ec9a67eab14a2bbf1e459983c0b35b5e 78 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 1.1E-17 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22335 ec9a67eab14a2bbf1e459983c0b35b5e 78 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 1.1E-17 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22335 ec9a67eab14a2bbf1e459983c0b35b5e 78 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 1.1E-17 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22335 ec9a67eab14a2bbf1e459983c0b35b5e 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 20 76 1.5E-22 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22335 ec9a67eab14a2bbf1e459983c0b35b5e 78 PANTHER PTHR13479 7 75 5.6E-26 T 23-04-2016 DC74_RS22335 ec9a67eab14a2bbf1e459983c0b35b5e 78 SUPERFAMILY SSF46911 8 76 1.83E-25 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS07970 ed6e06e47b9219eb266a5cd142621075 322 Pfam PF03466 LysR substrate binding domain 88 294 6.7E-40 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS07970 ed6e06e47b9219eb266a5cd142621075 322 PANTHER PTHR30346:SF2 1 313 5.4E-122 T 23-04-2016 DC74_RS07970 ed6e06e47b9219eb266a5cd142621075 322 SUPERFAMILY SSF46785 1 112 2.21E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07970 ed6e06e47b9219eb266a5cd142621075 322 SUPERFAMILY SSF53850 89 295 2.35E-34 T 23-04-2016 DC74_RS07970 ed6e06e47b9219eb266a5cd142621075 322 PANTHER PTHR30346 1 313 5.4E-122 T 23-04-2016 DC74_RS07970 ed6e06e47b9219eb266a5cd142621075 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 5.1E-21 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS07970 ed6e06e47b9219eb266a5cd142621075 322 Gene3D G3DSA:3.40.190.10 188 267 5.9E-18 T 23-04-2016 DC74_RS07970 ed6e06e47b9219eb266a5cd142621075 322 Gene3D G3DSA:1.10.10.10 1 88 4.4E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07970 ed6e06e47b9219eb266a5cd142621075 322 Gene3D G3DSA:3.40.190.10 90 187 2.1E-25 T 23-04-2016 DC74_RS11485 0f6b5db901916b0d075473b33e16786b 375 SUPERFAMILY SSF53474 128 268 2.61E-27 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS11485 0f6b5db901916b0d075473b33e16786b 375 SUPERFAMILY SSF53474 301 371 2.61E-27 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS11485 0f6b5db901916b0d075473b33e16786b 375 Gene3D G3DSA:3.40.50.1820 138 371 4.7E-24 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35205 074dede5d35edecab6cf16cb6bc76b3f 453 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 424 3.7E-128 T 23-04-2016 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 DC74_RS35205 074dede5d35edecab6cf16cb6bc76b3f 453 PANTHER PTHR11098 12 444 2.2E-130 T 23-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 DC74_RS35205 074dede5d35edecab6cf16cb6bc76b3f 453 PIRSF PIRSF000484 1 443 1.0E-115 T 23-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 DC74_RS35205 074dede5d35edecab6cf16cb6bc76b3f 453 PANTHER PTHR11098:SF1 12 444 2.2E-130 T 23-04-2016 DC74_RS35205 074dede5d35edecab6cf16cb6bc76b3f 453 Gene3D G3DSA:3.20.140.10 10 359 4.8E-85 T 23-04-2016 DC74_RS35205 074dede5d35edecab6cf16cb6bc76b3f 453 SUPERFAMILY SSF51690 138 435 8.54E-86 T 23-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 DC74_RS35205 074dede5d35edecab6cf16cb6bc76b3f 453 SUPERFAMILY SSF54675 10 136 4.32E-31 T 23-04-2016 DC74_RS35205 074dede5d35edecab6cf16cb6bc76b3f 453 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 155 296 4.6E-7 T 23-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 DC74_RS27235 6f737787ad2d866f26c7e69f5ba32522 343 PANTHER PTHR10366:SF253 21 328 3.8E-122 T 23-04-2016 DC74_RS27235 6f737787ad2d866f26c7e69f5ba32522 343 PANTHER PTHR10366 21 328 3.8E-122 T 23-04-2016 DC74_RS27235 6f737787ad2d866f26c7e69f5ba32522 343 SUPERFAMILY SSF51735 16 336 3.12E-92 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27235 6f737787ad2d866f26c7e69f5ba32522 343 Gene3D G3DSA:3.90.25.10 205 333 1.7E-29 T 23-04-2016 DC74_RS27235 6f737787ad2d866f26c7e69f5ba32522 343 Pfam PF16363 GDP-mannose 4,6 dehydratase 23 324 1.4E-65 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27235 6f737787ad2d866f26c7e69f5ba32522 343 Gene3D G3DSA:3.40.50.720 21 204 5.7E-63 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 Gene3D G3DSA:3.40.50.300 272 411 1.5E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 SMART SM01043 101 247 1.5E-29 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 Pfam PF00486 Transcriptional regulatory protein, C terminal 33 82 3.0E-5 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 SUPERFAMILY SSF46894 9 83 2.38E-8 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 Pfam PF03704 Bacterial transcriptional activator domain 101 247 3.8E-30 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 SUPERFAMILY SSF48452 96 268 2.8E-28 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 SUPERFAMILY SSF52540 261 539 1.0E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 SMART SM00862 21 94 8.0E-5 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 Gene3D G3DSA:1.25.40.10 113 230 6.1E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 Gene3D G3DSA:1.10.10.10 33 83 1.9E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 PRINTS PR00364 Disease resistance protein signature 370 384 1.1E-5 T 23-04-2016 DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 PRINTS PR00364 Disease resistance protein signature 476 490 1.1E-5 T 23-04-2016 DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 PRINTS PR00364 Disease resistance protein signature 290 305 1.1E-5 T 23-04-2016 DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 Gene3D G3DSA:1.25.40.10 789 1024 3.1E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS39525 12aaf5b97ddf66a6472842b3ad491be5 1094 PANTHER PTHR35807 4 324 5.2E-35 T 23-04-2016 DC74_RS20955 dce774d80b915c2f6402ce54eeee662c 105 PANTHER PTHR36114 1 105 8.9E-46 T 23-04-2016 DC74_RS20955 dce774d80b915c2f6402ce54eeee662c 105 PANTHER PTHR36114:SF3 1 105 8.9E-46 T 23-04-2016 DC74_RS20955 dce774d80b915c2f6402ce54eeee662c 105 SUPERFAMILY SSF51182 26 103 2.83E-20 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS20955 dce774d80b915c2f6402ce54eeee662c 105 Pfam PF07883 Cupin domain 33 100 2.1E-14 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS20955 dce774d80b915c2f6402ce54eeee662c 105 Gene3D G3DSA:2.60.120.10 2 104 4.4E-23 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS10780 3c27e126bbd468ad8a32882509203d06 129 PANTHER PTHR38445:SF2 4 82 7.9E-12 T 23-04-2016 DC74_RS10780 3c27e126bbd468ad8a32882509203d06 129 SUPERFAMILY SSF46785 14 85 1.0E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10780 3c27e126bbd468ad8a32882509203d06 129 PANTHER PTHR38445 4 82 7.9E-12 T 23-04-2016 DC74_RS10780 3c27e126bbd468ad8a32882509203d06 129 SMART SM00345 22 81 1.2E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10780 3c27e126bbd468ad8a32882509203d06 129 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 81 4.3E-13 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10780 3c27e126bbd468ad8a32882509203d06 129 Gene3D G3DSA:1.10.10.10 8 82 3.0E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 SMART SM00421 845 902 8.1E-18 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 Gene3D G3DSA:3.40.50.300 112 184 4.9E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 Gene3D G3DSA:3.40.50.300 9 66 4.9E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 848 862 1.6E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 862 878 1.6E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 878 890 1.6E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 PANTHER PTHR16305 3 404 4.5E-44 T 23-04-2016 DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 PANTHER PTHR16305:SF28 3 404 4.5E-44 T 23-04-2016 DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 SUPERFAMILY SSF46894 842 899 7.48E-16 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 SMART SM00382 27 200 7.8E-6 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 SUPERFAMILY SSF52540 6 219 1.99E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 Pfam PF00196 Bacterial regulatory proteins, luxR family 847 898 1.9E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 PANTHER PTHR16305 859 881 4.5E-44 T 23-04-2016 DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 PANTHER PTHR16305:SF28 859 881 4.5E-44 T 23-04-2016 DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 Pfam PF13191 AAA ATPase domain 7 163 8.4E-21 T 23-04-2016 DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 Gene3D G3DSA:1.10.10.10 845 898 4.1E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04645 f39733bb8fe0e3afc78b7db210cfcda5 906 ProSitePatterns PS00622 LuxR-type HTH domain signature. 862 889 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS09675 3205f3b5cf4874b45659e654e08e87c9 277 PANTHER PTHR10587 87 276 1.5E-30 T 23-04-2016 DC74_RS09675 3205f3b5cf4874b45659e654e08e87c9 277 SUPERFAMILY SSF88713 75 276 3.71E-38 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS09675 3205f3b5cf4874b45659e654e08e87c9 277 Gene3D G3DSA:3.20.20.370 76 276 4.6E-37 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS09675 3205f3b5cf4874b45659e654e08e87c9 277 Pfam PF01522 Polysaccharide deacetylase 87 208 1.8E-15 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS04755 cab3b3d14ea48751069b9a49d3fc69aa 233 PANTHER PTHR30136 1 230 3.8E-18 T 23-04-2016 DC74_RS04755 cab3b3d14ea48751069b9a49d3fc69aa 233 SMART SM00346 1 84 0.0045 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS04755 cab3b3d14ea48751069b9a49d3fc69aa 233 Gene3D G3DSA:1.10.10.10 1 59 1.9E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04755 cab3b3d14ea48751069b9a49d3fc69aa 233 SUPERFAMILY SSF46785 1 64 1.26E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04755 cab3b3d14ea48751069b9a49d3fc69aa 233 Pfam PF01614 Bacterial transcriptional regulator 124 229 7.7E-6 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS04755 cab3b3d14ea48751069b9a49d3fc69aa 233 SUPERFAMILY SSF55781 73 227 3.66E-17 T 23-04-2016 IPR029016 GAF domain-like DC74_RS04755 cab3b3d14ea48751069b9a49d3fc69aa 233 Pfam PF09339 IclR helix-turn-helix domain 1 47 8.3E-9 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS04755 cab3b3d14ea48751069b9a49d3fc69aa 233 Gene3D G3DSA:3.30.450.40 71 229 1.8E-18 T 23-04-2016 IPR029016 GAF domain-like DC74_RS06085 bc6f3d555b9111eed33aa38bbb1d49b4 494 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 61 180 8.7E-9 T 23-04-2016 DC74_RS00965 94230143433572b1fec4946c5516bfa4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.82E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00965 94230143433572b1fec4946c5516bfa4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.82E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00965 94230143433572b1fec4946c5516bfa4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.82E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00965 94230143433572b1fec4946c5516bfa4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.82E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00965 94230143433572b1fec4946c5516bfa4 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.82E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00965 94230143433572b1fec4946c5516bfa4 247 PANTHER PTHR24322 13 182 6.1E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00965 94230143433572b1fec4946c5516bfa4 247 Gene3D G3DSA:3.40.50.720 8 235 1.4E-60 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00965 94230143433572b1fec4946c5516bfa4 247 SUPERFAMILY SSF51735 8 234 2.08E-60 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00965 94230143433572b1fec4946c5516bfa4 247 Pfam PF00106 short chain dehydrogenase 10 194 1.3E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00965 94230143433572b1fec4946c5516bfa4 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 177 0.0092 T 23-04-2016 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Gene3D G3DSA:3.30.70.250 678 738 4.9E-6 T 23-04-2016 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 168 184 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Gene3D G3DSA:3.40.50.150 1369 1568 7.7E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SUPERFAMILY SSF52151 747 844 3.14E-61 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SUPERFAMILY SSF52151 553 681 3.14E-61 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SMART SM00829 1852 2166 9.8E-127 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Pfam PF14765 Polyketide synthase dehydratase 923 1198 1.5E-47 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SMART SM00825 Beta-ketoacyl synthase 6 431 7.2E-163 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Pfam PF00698 Acyl transferase domain 556 859 3.2E-68 T 23-04-2016 IPR014043 Acyl transferase DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SUPERFAMILY SSF53335 1385 1569 5.83E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Pfam PF08659 KR domain 2187 2363 2.5E-49 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SMART SM00826 923 1087 2.1E-27 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SUPERFAMILY SSF50129 1848 1988 1.16E-27 T 23-04-2016 IPR011032 GroES-like DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Gene3D G3DSA:3.90.180.10 1851 1990 1.1E-41 T 23-04-2016 IPR011032 GroES-like DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Gene3D G3DSA:3.40.366.10 746 867 3.2E-66 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Gene3D G3DSA:3.40.366.10 552 676 3.2E-66 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 382 488 2.2E-15 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Pfam PF00107 Zinc-binding dehydrogenase 1995 2106 1.2E-22 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 PANTHER PTHR11712 462 1661 0.0 T 23-04-2016 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 PANTHER PTHR11712 1679 2533 0.0 T 23-04-2016 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 PANTHER PTHR11712 6 440 0.0 T 23-04-2016 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1870 1935 1.1E-6 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Gene3D G3DSA:3.40.47.10 4 267 3.0E-87 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Pfam PF00550 Phosphopantetheine attachment site 2463 2527 3.4E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Gene3D G3DSA:3.40.47.10 269 430 6.8E-53 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Pfam PF08242 Methyltransferase domain 1416 1516 1.2E-18 T 23-04-2016 IPR013217 Methyltransferase type 12 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Gene3D G3DSA:3.40.50.720 1991 2097 2.1E-26 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2187 2365 2.9E-34 T 23-04-2016 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 263 379 3.3E-38 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SUPERFAMILY SSF51735 2186 2405 9.13E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Gene3D G3DSA:1.10.1200.10 2461 2542 2.4E-9 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SUPERFAMILY SSF53901 4 375 3.9E-83 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SUPERFAMILY SSF53901 404 426 3.9E-83 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SUPERFAMILY SSF51735 1623 1831 3.23E-11 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SUPERFAMILY SSF51735 1956 2118 3.53E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Gene3D G3DSA:3.40.50.720 2188 2390 2.3E-32 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SUPERFAMILY SSF55048 679 744 2.35E-10 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SUPERFAMILY SSF47336 2461 2539 7.85E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 253 1.6E-73 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SMART SM00823 Phosphopantetheine attachment site 2461 2533 2.5E-4 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2488 2503 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS40010 acc7a1709b062867cee35efe195e60e0 2553 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 557 857 2.1E-94 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS05500 310dc8867cda6fddb6a1ea7c3d831c21 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 236 2.6E-40 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS05500 310dc8867cda6fddb6a1ea7c3d831c21 341 PANTHER PTHR10366:SF12 2 327 1.6E-88 T 23-04-2016 DC74_RS05500 310dc8867cda6fddb6a1ea7c3d831c21 341 SUPERFAMILY SSF51735 2 312 5.19E-53 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05500 310dc8867cda6fddb6a1ea7c3d831c21 341 PANTHER PTHR10366 2 327 1.6E-88 T 23-04-2016 DC74_RS05500 310dc8867cda6fddb6a1ea7c3d831c21 341 Gene3D G3DSA:3.40.50.720 2 297 2.9E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS28080 a3ab7ee9fb58fe944770a626d97a1034 449 Gene3D G3DSA:1.10.3430.10 18 403 2.2E-136 T 23-04-2016 IPR029020 Ammonium/urea transporter DC74_RS28080 a3ab7ee9fb58fe944770a626d97a1034 449 PANTHER PTHR11730 21 428 2.3E-179 T 23-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 DC74_RS28080 a3ab7ee9fb58fe944770a626d97a1034 449 SUPERFAMILY SSF111352 19 403 6.28E-124 T 23-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 DC74_RS28080 a3ab7ee9fb58fe944770a626d97a1034 449 ProSitePatterns PS01219 Ammonium transporters signature. 177 202 - T 23-04-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 DC74_RS28080 a3ab7ee9fb58fe944770a626d97a1034 449 Pfam PF00909 Ammonium Transporter Family 25 422 1.7E-127 T 23-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 DC74_RS28080 a3ab7ee9fb58fe944770a626d97a1034 449 PANTHER PTHR11730:SF17 21 428 2.3E-179 T 23-04-2016 DC74_RS28080 a3ab7ee9fb58fe944770a626d97a1034 449 TIGRFAM TIGR00836 amt: ammonium transporter 22 422 5.2E-136 T 23-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 SUPERFAMILY SSF54631 339 458 2.53E-15 T 23-04-2016 DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 SMART SM00116 412 457 3.2 T 23-04-2016 IPR000644 CBS domain DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 SMART SM00116 339 395 0.092 T 23-04-2016 IPR000644 CBS domain DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 PANTHER PTHR10314 7 353 3.8E-244 T 23-04-2016 DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 296 5.2E-72 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 4 457 2.9E-212 T 23-04-2016 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801|UniPathway: UPA00136 DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 SUPERFAMILY SSF53686 2 317 1.02E-99 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 Gene3D G3DSA:3.40.50.1100 43 147 1.7E-39 T 23-04-2016 DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 PANTHER PTHR10314:SF104 7 353 3.8E-244 T 23-04-2016 DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 Gene3D G3DSA:3.40.50.1100 153 313 3.4E-73 T 23-04-2016 DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 Gene3D G3DSA:3.40.50.1100 2 42 3.4E-73 T 23-04-2016 DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 23-04-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 Gene3D G3DSA:3.10.580.10 338 458 2.7E-19 T 23-04-2016 DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 Pfam PF00571 CBS domain 339 394 5.9E-5 T 23-04-2016 IPR000644 CBS domain DC74_RS17275 63596b8e9bf8ebf9825f7f8861ae7295 462 Pfam PF00571 CBS domain 410 457 0.0014 T 23-04-2016 IPR000644 CBS domain DC74_RS35325 2ff41720e6ba221e729b3d29b3e517bc 445 Pfam PF03471 Transporter associated domain 363 431 4.5E-16 T 23-04-2016 IPR005170 Transporter-associated domain DC74_RS35325 2ff41720e6ba221e729b3d29b3e517bc 445 Pfam PF01595 Domain of unknown function DUF21 9 201 1.4E-29 T 23-04-2016 IPR002550 Domain of unknown function DUF21 DC74_RS35325 2ff41720e6ba221e729b3d29b3e517bc 445 Gene3D G3DSA:3.10.580.10 209 330 2.0E-16 T 23-04-2016 DC74_RS35325 2ff41720e6ba221e729b3d29b3e517bc 445 PANTHER PTHR22777:SF5 4 442 9.3E-251 T 23-04-2016 DC74_RS35325 2ff41720e6ba221e729b3d29b3e517bc 445 SUPERFAMILY SSF56176 363 438 2.26E-16 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS35325 2ff41720e6ba221e729b3d29b3e517bc 445 Pfam PF00571 CBS domain 219 273 0.0035 T 23-04-2016 IPR000644 CBS domain DC74_RS35325 2ff41720e6ba221e729b3d29b3e517bc 445 Pfam PF00571 CBS domain 284 335 5.2E-4 T 23-04-2016 IPR000644 CBS domain DC74_RS35325 2ff41720e6ba221e729b3d29b3e517bc 445 Gene3D G3DSA:3.30.465.10 331 431 8.8E-21 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS35325 2ff41720e6ba221e729b3d29b3e517bc 445 SMART SM01091 357 434 3.0E-19 T 23-04-2016 IPR005170 Transporter-associated domain DC74_RS35325 2ff41720e6ba221e729b3d29b3e517bc 445 SUPERFAMILY SSF54631 213 347 3.54E-25 T 23-04-2016 DC74_RS35325 2ff41720e6ba221e729b3d29b3e517bc 445 PANTHER PTHR22777 4 442 9.3E-251 T 23-04-2016 DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 Pfam PF00672 HAMP domain 130 197 3.0E-11 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 Gene3D G3DSA:3.30.565.10 272 396 3.1E-24 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 PANTHER PTHR24423 143 415 2.4E-61 T 23-04-2016 DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 PANTHER PTHR24423 1 12 2.4E-61 T 23-04-2016 DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 SUPERFAMILY SSF47384 186 263 5.3E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 PANTHER PTHR24423:SF477 143 415 2.4E-61 T 23-04-2016 DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 PANTHER PTHR24423:SF477 1 12 2.4E-61 T 23-04-2016 DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 Gene3D G3DSA:1.10.287.130 193 263 1.4E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 394 4.5E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 390 4.0E-7 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 4.0E-7 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 SMART SM00388 202 267 6.9E-9 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 SMART SM00387 309 410 6.6E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 SUPERFAMILY SSF55874 270 397 8.51E-23 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17160 7aef492cf0a32cf9c689e84bcd23f386 415 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 263 1.0E-8 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS26610 edf5711cd4d5693db6aed78b4c387f02 148 Pfam PF00717 Peptidase S24-like 32 93 1.3E-10 T 23-04-2016 IPR019759 Peptidase S24/S26A/S26B DC74_RS26610 edf5711cd4d5693db6aed78b4c387f02 148 TIGRFAM TIGR02754 sod_Ni_protease: nickel-type superoxide dismutase maturation protease 32 112 4.5E-22 T 23-04-2016 IPR014124 Peptidase S26A, superoxide dismutase maturation protease, nickel-type DC74_RS26610 edf5711cd4d5693db6aed78b4c387f02 148 Gene3D G3DSA:2.10.109.10 28 124 1.1E-18 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain DC74_RS26610 edf5711cd4d5693db6aed78b4c387f02 148 PANTHER PTHR12383 27 120 2.8E-13 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS26610 edf5711cd4d5693db6aed78b4c387f02 148 SUPERFAMILY SSF51306 27 126 2.09E-21 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C DC74_RS26370 575cfa0b115abad557b83b079540fb49 130 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 10 84 1.8E-30 T 23-04-2016 IPR024020 Anti sigma-R factor, mycothiol system,RsrA DC74_RS26370 575cfa0b115abad557b83b079540fb49 130 Pfam PF13490 Putative zinc-finger 11 44 4.2E-10 T 23-04-2016 IPR027383 Putative zinc-finger DC74_RS26370 575cfa0b115abad557b83b079540fb49 130 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 4 85 3.2E-34 T 23-04-2016 IPR014295 Anti-sigma factor DC74_RS04475 aa4270e6f23f3c09a6f7e236cccfb758 588 Pfam PF13193 AMP-binding enzyme C-terminal domain 441 518 3.0E-14 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS04475 aa4270e6f23f3c09a6f7e236cccfb758 588 PANTHER PTHR24095 28 518 2.9E-109 T 23-04-2016 DC74_RS04475 aa4270e6f23f3c09a6f7e236cccfb758 588 Pfam PF00501 AMP-binding enzyme 36 432 2.7E-76 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS04475 aa4270e6f23f3c09a6f7e236cccfb758 588 Gene3D G3DSA:3.30.300.30 429 534 1.2E-27 T 23-04-2016 DC74_RS04475 aa4270e6f23f3c09a6f7e236cccfb758 588 Gene3D G3DSA:3.40.50.980 27 180 2.4E-29 T 23-04-2016 DC74_RS04475 aa4270e6f23f3c09a6f7e236cccfb758 588 Gene3D G3DSA:2.30.38.10 344 426 3.6E-16 T 23-04-2016 DC74_RS04475 aa4270e6f23f3c09a6f7e236cccfb758 588 ProSitePatterns PS00455 Putative AMP-binding domain signature. 172 183 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS04475 aa4270e6f23f3c09a6f7e236cccfb758 588 SUPERFAMILY SSF56801 18 544 3.27E-121 T 23-04-2016 DC74_RS04475 aa4270e6f23f3c09a6f7e236cccfb758 588 Gene3D G3DSA:3.40.50.980 181 343 7.7E-36 T 23-04-2016 DC74_RS18260 197accf5f01c5a04c9a02d886a6f2ee4 383 Gene3D G3DSA:3.40.47.10 247 306 5.4E-4 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS18260 197accf5f01c5a04c9a02d886a6f2ee4 383 Gene3D G3DSA:3.40.47.10 147 183 5.4E-4 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS18260 197accf5f01c5a04c9a02d886a6f2ee4 383 PIRSF PIRSF000429 4 368 5.1E-21 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS18260 197accf5f01c5a04c9a02d886a6f2ee4 383 Gene3D G3DSA:3.40.47.10 199 226 4.0E-8 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS18260 197accf5f01c5a04c9a02d886a6f2ee4 383 Gene3D G3DSA:3.40.47.10 12 115 4.0E-8 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS18260 197accf5f01c5a04c9a02d886a6f2ee4 383 PANTHER PTHR18919:SF108 4 360 7.6E-84 T 23-04-2016 DC74_RS18260 197accf5f01c5a04c9a02d886a6f2ee4 383 SUPERFAMILY SSF53901 10 229 3.26E-15 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS18260 197accf5f01c5a04c9a02d886a6f2ee4 383 PANTHER PTHR18919 4 360 7.6E-84 T 23-04-2016 DC74_RS18260 197accf5f01c5a04c9a02d886a6f2ee4 383 SUPERFAMILY SSF53901 252 356 7.69E-12 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS18515 e5718bb51050a67902a79b6ca63bece3 219 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 203 8.7E-57 T 23-04-2016 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 DC74_RS18515 e5718bb51050a67902a79b6ca63bece3 219 SUPERFAMILY SSF53067 107 201 2.07E-13 T 23-04-2016 DC74_RS18515 e5718bb51050a67902a79b6ca63bece3 219 SUPERFAMILY SSF53067 2 101 4.75E-22 T 23-04-2016 DC74_RS18515 e5718bb51050a67902a79b6ca63bece3 219 Gene3D G3DSA:3.30.420.40 116 174 3.0E-12 T 23-04-2016 DC74_RS18515 e5718bb51050a67902a79b6ca63bece3 219 PANTHER PTHR11735 1 147 1.6E-36 T 23-04-2016 DC74_RS18515 e5718bb51050a67902a79b6ca63bece3 219 Gene3D G3DSA:3.30.420.40 2 115 3.4E-36 T 23-04-2016 DC74_RS18515 e5718bb51050a67902a79b6ca63bece3 219 PANTHER PTHR11735:SF11 1 147 1.6E-36 T 23-04-2016 DC74_RS18515 e5718bb51050a67902a79b6ca63bece3 219 Pfam PF00814 Glycoprotease family 30 144 4.8E-28 T 23-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS21170 5d1448864391999daddde74892192106 429 SUPERFAMILY SSF46589 2 111 1.62E-23 T 23-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 DC74_RS21170 5d1448864391999daddde74892192106 429 PIRSF PIRSF001529 1 427 6.7E-140 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 DC74_RS21170 5d1448864391999daddde74892192106 429 SUPERFAMILY SSF55681 131 421 2.93E-83 T 23-04-2016 DC74_RS21170 5d1448864391999daddde74892192106 429 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 418 1.3E-131 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 DC74_RS21170 5d1448864391999daddde74892192106 429 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 9.2E-30 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 DC74_RS21170 5d1448864391999daddde74892192106 429 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 9.2E-30 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 DC74_RS21170 5d1448864391999daddde74892192106 429 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 9.2E-30 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 DC74_RS21170 5d1448864391999daddde74892192106 429 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 9.2E-30 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 DC74_RS21170 5d1448864391999daddde74892192106 429 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 9.2E-30 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 DC74_RS21170 5d1448864391999daddde74892192106 429 Gene3D G3DSA:3.30.930.10 104 422 5.5E-123 T 23-04-2016 DC74_RS21170 5d1448864391999daddde74892192106 429 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 401 4.8E-29 T 23-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS21170 5d1448864391999daddde74892192106 429 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 1.7E-23 T 23-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 DC74_RS21170 5d1448864391999daddde74892192106 429 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 423 39.034 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 DC74_RS21170 5d1448864391999daddde74892192106 429 Gene3D G3DSA:1.10.287.40 2 102 3.5E-27 T 23-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 DC74_RS21170 5d1448864391999daddde74892192106 429 PANTHER PTHR11778 1 427 3.3E-289 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 DC74_RS21170 5d1448864391999daddde74892192106 429 PANTHER PTHR11778:SF8 1 427 3.3E-289 T 23-04-2016 DC74_RS01140 641a0730ef2c6065db5457bb7113f5f0 215 PANTHER PTHR10108:SF811 28 208 2.2E-22 T 23-04-2016 DC74_RS01140 641a0730ef2c6065db5457bb7113f5f0 215 SUPERFAMILY SSF53335 11 214 7.91E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS01140 641a0730ef2c6065db5457bb7113f5f0 215 Pfam PF13649 Methyltransferase domain 54 144 1.7E-17 T 23-04-2016 DC74_RS01140 641a0730ef2c6065db5457bb7113f5f0 215 PANTHER PTHR10108 28 208 2.2E-22 T 23-04-2016 DC74_RS01140 641a0730ef2c6065db5457bb7113f5f0 215 Gene3D G3DSA:3.40.50.150 10 214 1.1E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 Pfam PF00571 CBS domain 101 149 8.8E-8 T 23-04-2016 IPR000644 CBS domain DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 Pfam PF00571 CBS domain 157 212 4.1E-6 T 23-04-2016 IPR000644 CBS domain DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 Gene3D G3DSA:3.20.20.70 11 498 1.1E-194 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 SUPERFAMILY SSF51412 11 98 1.31E-119 T 23-04-2016 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 SUPERFAMILY SSF51412 224 490 1.31E-119 T 23-04-2016 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 SMART SM01240 15 486 0.0 T 23-04-2016 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 301 313 - T 23-04-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Reactome: REACT_1698 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 16 499 84.06 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 SMART SM00116 165 213 4.3E-8 T 23-04-2016 IPR000644 CBS domain DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 SMART SM00116 104 152 1.8E-7 T 23-04-2016 IPR000644 CBS domain DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 PIRSF PIRSF000130 7 500 6.2E-201 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 16 468 5.7E-184 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 PANTHER PTHR11911:SF6 1 288 1.7E-225 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 PANTHER PTHR11911:SF6 306 499 1.7E-225 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 SUPERFAMILY SSF54631 92 211 1.39E-29 T 23-04-2016 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 16 486 2.8E-157 T 23-04-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 PANTHER PTHR11911 1 288 1.7E-225 T 23-04-2016 DC74_RS18440 0b6d0677f678504cd0d46c68bc21c04a 500 PANTHER PTHR11911 306 499 1.7E-225 T 23-04-2016 DC74_RS30755 e25f99604eb26401d114eb6b4cfaa748 278 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 267 2.2E-7 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS30755 e25f99604eb26401d114eb6b4cfaa748 278 SUPERFAMILY SSF56219 2 175 5.63E-22 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS30755 e25f99604eb26401d114eb6b4cfaa748 278 SUPERFAMILY SSF56219 205 275 5.63E-22 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS30755 e25f99604eb26401d114eb6b4cfaa748 278 Gene3D G3DSA:3.60.10.10 2 274 1.2E-5 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS40425 031fc647852f9053e6bec73e846baa79 283 Pfam PF00583 Acetyltransferase (GNAT) family 58 130 2.2E-12 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS40425 031fc647852f9053e6bec73e846baa79 283 PRINTS PR00502 NUDIX hydrolase family signature 191 206 1.5E-5 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS40425 031fc647852f9053e6bec73e846baa79 283 PRINTS PR00502 NUDIX hydrolase family signature 177 191 1.5E-5 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS40425 031fc647852f9053e6bec73e846baa79 283 SUPERFAMILY SSF55729 7 141 9.39E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS40425 031fc647852f9053e6bec73e846baa79 283 SUPERFAMILY SSF55811 152 277 1.35E-23 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS40425 031fc647852f9053e6bec73e846baa79 283 PANTHER PTHR23091:SF266 7 184 6.9E-17 T 23-04-2016 DC74_RS40425 031fc647852f9053e6bec73e846baa79 283 Gene3D G3DSA:3.90.79.10 154 278 3.3E-22 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS40425 031fc647852f9053e6bec73e846baa79 283 PANTHER PTHR23091 7 184 6.9E-17 T 23-04-2016 DC74_RS40425 031fc647852f9053e6bec73e846baa79 283 ProSitePatterns PS00893 Nudix box signature. 182 203 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS40425 031fc647852f9053e6bec73e846baa79 283 Gene3D G3DSA:3.40.630.30 4 141 1.9E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS40425 031fc647852f9053e6bec73e846baa79 283 Pfam PF00293 NUDIX domain 162 274 3.6E-13 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS23095 ed04f5c57eac3d294b314f720266559d 189 Gene3D G3DSA:3.40.50.360 8 180 2.9E-46 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS23095 ed04f5c57eac3d294b314f720266559d 189 Pfam PF03358 NADPH-dependent FMN reductase 8 140 1.4E-32 T 23-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 DC74_RS23095 ed04f5c57eac3d294b314f720266559d 189 PANTHER PTHR30543 3 187 2.9E-43 T 23-04-2016 DC74_RS23095 ed04f5c57eac3d294b314f720266559d 189 PANTHER PTHR30543:SF1 3 187 2.9E-43 T 23-04-2016 DC74_RS23095 ed04f5c57eac3d294b314f720266559d 189 SUPERFAMILY SSF52218 8 164 1.46E-34 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 PIRSF PIRSF000106 64 474 2.6E-81 T 23-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 SUPERFAMILY SSF53223 87 236 3.88E-57 T 23-04-2016 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 Pfam PF03949 Malic enzyme, NAD binding domain 240 462 1.6E-21 T 23-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 Gene3D G3DSA:3.40.50.720 236 464 1.1E-69 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 Gene3D G3DSA:3.30.70.260 24 78 8.7E-4 T 23-04-2016 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 SMART SM01274 93 226 6.0E-85 T 23-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 PANTHER PTHR23406 52 468 8.9E-170 T 23-04-2016 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 SMART SM00919 238 465 4.0E-109 T 23-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 SUPERFAMILY SSF51735 238 471 2.84E-66 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 PANTHER PTHR23406:SF23 52 468 8.9E-170 T 23-04-2016 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 Gene3D G3DSA:3.40.50.10380 93 235 1.4E-55 T 23-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 PRINTS PR00072 Malic enzyme signature 234 250 4.2E-12 T 23-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 PRINTS PR00072 Malic enzyme signature 265 281 4.2E-12 T 23-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 PRINTS PR00072 Malic enzyme signature 155 177 4.2E-12 T 23-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 PRINTS PR00072 Malic enzyme signature 358 374 4.2E-12 T 23-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 DC74_RS16620 21fc58f025329c575f211fdde6fd5340 477 Pfam PF00390 Malic enzyme, N-terminal domain 94 226 3.9E-31 T 23-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DC74_RS27795 d1ebf366047c9901efd96b8cc27f3783 527 SUPERFAMILY SSF52096 15 267 2.16E-73 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS27795 d1ebf366047c9901efd96b8cc27f3783 527 Gene3D G3DSA:3.90.226.10 7 265 3.0E-74 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS27795 d1ebf366047c9901efd96b8cc27f3783 527 SUPERFAMILY SSF52096 236 526 4.98E-90 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS27795 d1ebf366047c9901efd96b8cc27f3783 527 PANTHER PTHR22855:SF14 11 527 0.0 T 23-04-2016 DC74_RS27795 d1ebf366047c9901efd96b8cc27f3783 527 Gene3D G3DSA:3.90.226.10 266 526 3.5E-99 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS27795 d1ebf366047c9901efd96b8cc27f3783 527 Pfam PF01039 Carboxyl transferase domain 40 524 3.7E-196 T 23-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 DC74_RS27795 d1ebf366047c9901efd96b8cc27f3783 527 PANTHER PTHR22855 11 527 0.0 T 23-04-2016 DC74_RS31980 aeadedc23451f4d289e10d3b7067e52a 306 Pfam PF03631 Virulence factor BrkB 42 295 1.2E-52 T 23-04-2016 IPR017039 Virulence factor BrkB DC74_RS31980 aeadedc23451f4d289e10d3b7067e52a 306 PANTHER PTHR30213 1 295 7.9E-49 T 23-04-2016 DC74_RS31980 aeadedc23451f4d289e10d3b7067e52a 306 PIRSF PIRSF035875 14 305 6.8E-60 T 23-04-2016 IPR017039 Virulence factor BrkB DC74_RS31980 aeadedc23451f4d289e10d3b7067e52a 306 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 41 293 9.6E-23 T 23-04-2016 IPR017039 Virulence factor BrkB DC74_RS31980 aeadedc23451f4d289e10d3b7067e52a 306 PANTHER PTHR30213:SF2 1 295 7.9E-49 T 23-04-2016 DC74_RS32225 596d1a1cbdc88fafd86b31c345911c10 258 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS32225 596d1a1cbdc88fafd86b31c345911c10 258 Gene3D G3DSA:3.40.50.300 4 223 2.0E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32225 596d1a1cbdc88fafd86b31c345911c10 258 SMART SM00382 30 217 6.5E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS32225 596d1a1cbdc88fafd86b31c345911c10 258 Pfam PF00005 ABC transporter 21 169 1.6E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS32225 596d1a1cbdc88fafd86b31c345911c10 258 SUPERFAMILY SSF52540 5 223 3.41E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32225 596d1a1cbdc88fafd86b31c345911c10 258 PANTHER PTHR24220 6 225 1.2E-103 T 23-04-2016 DC74_RS32225 596d1a1cbdc88fafd86b31c345911c10 258 PANTHER PTHR24220:SF578 6 225 1.2E-103 T 23-04-2016 DC74_RS36255 93c8c935f1fda8604312b81079af5bc8 353 Gene3D G3DSA:2.60.120.330 11 333 2.3E-83 T 23-04-2016 IPR027443 Isopenicillin N synthase-like DC74_RS36255 93c8c935f1fda8604312b81079af5bc8 353 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 190 292 6.8E-18 T 23-04-2016 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 DC74_RS36255 93c8c935f1fda8604312b81079af5bc8 353 PANTHER PTHR10209:SF68 12 337 1.8E-80 T 23-04-2016 DC74_RS36255 93c8c935f1fda8604312b81079af5bc8 353 SUPERFAMILY SSF51197 11 330 1.44E-81 T 23-04-2016 DC74_RS36255 93c8c935f1fda8604312b81079af5bc8 353 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 13 141 8.1E-23 T 23-04-2016 IPR026992 Non-haem dioxygenase N-terminal domain DC74_RS36255 93c8c935f1fda8604312b81079af5bc8 353 PANTHER PTHR10209 12 337 1.8E-80 T 23-04-2016 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 SUPERFAMILY SSF88946 27 132 2.04E-31 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 SUPERFAMILY SSF88659 199 280 4.67E-15 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 Pfam PF04542 Sigma-70 region 2 63 132 2.0E-16 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 87 100 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 SUPERFAMILY SSF88659 136 211 4.8E-15 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 Pfam PF04545 Sigma-70, region 4 230 278 3.9E-17 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 Gene3D G3DSA:1.10.10.10 226 280 7.8E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17205 6abd5416897964e9773036932d6796d7 284 PRINTS PR00046 Major sigma-70 factor signature 250 265 6.8E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 PRINTS PR00046 Major sigma-70 factor signature 233 245 6.8E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 PRINTS PR00046 Major sigma-70 factor signature 87 100 6.8E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 Gene3D G3DSA:1.10.601.10 44 130 6.3E-25 T 23-04-2016 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 60 279 2.0E-31 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 Gene3D G3DSA:1.10.10.10 131 186 2.3E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17205 6abd5416897964e9773036932d6796d7 284 PANTHER PTHR30385 21 284 1.7E-130 T 23-04-2016 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 58 279 3.9E-93 T 23-04-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 Pfam PF04539 Sigma-70 region 3 143 209 1.6E-15 T 23-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17205 6abd5416897964e9773036932d6796d7 284 PANTHER PTHR30385:SF4 21 284 1.7E-130 T 23-04-2016 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 Pfam PF13180 PDZ domain 354 443 1.5E-21 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 SUPERFAMILY SSF50494 125 359 1.22E-54 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 Gene3D G3DSA:2.40.10.10 150 229 4.0E-27 T 23-04-2016 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 PRINTS PR00834 HtrA/DegQ protease family signature 273 290 3.6E-43 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 PRINTS PR00834 HtrA/DegQ protease family signature 392 404 3.6E-43 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 PRINTS PR00834 HtrA/DegQ protease family signature 165 177 3.6E-43 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 PRINTS PR00834 HtrA/DegQ protease family signature 295 312 3.6E-43 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 PRINTS PR00834 HtrA/DegQ protease family signature 189 209 3.6E-43 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 PRINTS PR00834 HtrA/DegQ protease family signature 230 254 3.6E-43 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 PANTHER PTHR22939 324 447 3.2E-138 T 23-04-2016 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 Gene3D G3DSA:2.30.42.10 357 447 1.8E-20 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 PANTHER PTHR22939 49 308 3.2E-138 T 23-04-2016 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 SUPERFAMILY SSF50156 335 443 4.34E-20 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 Pfam PF13365 Trypsin-like peptidase domain 156 302 7.8E-33 T 23-04-2016 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 Gene3D G3DSA:2.40.10.10 230 356 8.0E-42 T 23-04-2016 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 SMART SM00228 354 434 1.3E-7 T 23-04-2016 IPR001478 PDZ domain GO:0005515 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 PANTHER PTHR22939:SF79 324 447 3.2E-138 T 23-04-2016 DC74_RS25985 08a4b2ba91bb4b914574d4512821ff08 449 PANTHER PTHR22939:SF79 49 308 3.2E-138 T 23-04-2016 DC74_RS27440 b6a2812c762e86871b1df29377bce90e 218 Gene3D G3DSA:1.20.144.10 32 203 2.5E-30 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS27440 b6a2812c762e86871b1df29377bce90e 218 SMART SM00014 79 193 3.2E-18 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS27440 b6a2812c762e86871b1df29377bce90e 218 Pfam PF01569 PAP2 superfamily 85 197 3.4E-23 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS27440 b6a2812c762e86871b1df29377bce90e 218 SUPERFAMILY SSF48317 22 204 1.02E-32 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS27440 b6a2812c762e86871b1df29377bce90e 218 PANTHER PTHR14969:SF24 81 208 1.1E-34 T 23-04-2016 DC74_RS27440 b6a2812c762e86871b1df29377bce90e 218 PANTHER PTHR14969:SF24 41 57 1.1E-34 T 23-04-2016 DC74_RS27440 b6a2812c762e86871b1df29377bce90e 218 PANTHER PTHR14969 81 208 1.1E-34 T 23-04-2016 DC74_RS27440 b6a2812c762e86871b1df29377bce90e 218 PANTHER PTHR14969 41 57 1.1E-34 T 23-04-2016 DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 PANTHER PTHR11908 5 442 5.0E-167 T 23-04-2016 DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 PANTHER PTHR11908 459 767 5.0E-167 T 23-04-2016 DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 44 148 1.2E-27 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 Gene3D G3DSA:3.30.365.10 370 473 2.2E-40 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 Gene3D G3DSA:3.30.365.10 641 767 2.2E-40 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 Gene3D G3DSA:3.30.365.10 293 367 3.9E-29 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 Gene3D G3DSA:3.30.365.10 138 197 3.9E-29 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 SUPERFAMILY SSF56003 152 767 2.62E-118 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 SUPERFAMILY SSF54665 18 150 3.79E-37 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 Gene3D G3DSA:3.30.365.10 200 290 1.1E-19 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 Gene3D G3DSA:3.90.1170.50 19 137 6.2E-39 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 Gene3D G3DSA:3.30.365.10 483 640 5.8E-19 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 SMART SM01008 43 149 1.1E-42 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS16560 5265ef69859e42bbc278da050be08be8 774 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 171 712 2.0E-107 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS32675 d9b538adcf621677a9e175565c719660 186 SUPERFAMILY SSF52540 10 185 1.63E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32675 d9b538adcf621677a9e175565c719660 186 Gene3D G3DSA:3.40.50.300 11 184 3.6E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS31855 f6fae67c3cd002f676d7f691ec422ae3 596 Gene3D G3DSA:3.40.50.1820 247 368 7.0E-46 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31855 f6fae67c3cd002f676d7f691ec422ae3 596 Gene3D G3DSA:3.40.50.1820 32 198 7.0E-46 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31855 f6fae67c3cd002f676d7f691ec422ae3 596 Gene3D G3DSA:2.60.120.260 394 590 7.6E-25 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS31855 f6fae67c3cd002f676d7f691ec422ae3 596 SUPERFAMILY SSF49785 398 591 1.34E-25 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS31855 f6fae67c3cd002f676d7f691ec422ae3 596 SMART SM00939 360 587 1.4E-9 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 DC74_RS31855 f6fae67c3cd002f676d7f691ec422ae3 596 SUPERFAMILY SSF53474 274 371 6.57E-36 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31855 f6fae67c3cd002f676d7f691ec422ae3 596 SUPERFAMILY SSF53474 15 194 6.57E-36 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31855 f6fae67c3cd002f676d7f691ec422ae3 596 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 49 332 7.6E-21 T 23-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 DC74_RS31855 f6fae67c3cd002f676d7f691ec422ae3 596 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 463 565 7.7E-11 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 PANTHER PTHR24220:SF132 11 420 1.5E-137 T 23-04-2016 DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 SUPERFAMILY SSF52540 9 260 4.39E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 512 544 1.1E-7 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 271 0.0029 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 Gene3D G3DSA:3.40.50.300 8 262 1.3E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 Gene3D G3DSA:3.40.50.300 288 534 2.2E-82 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 ProSitePatterns PS00211 ABC transporters family signature. 433 447 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 PANTHER PTHR24220 11 420 1.5E-137 T 23-04-2016 DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 SUPERFAMILY SSF52540 289 531 3.27E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 Pfam PF00005 ABC transporter 310 460 6.3E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 Pfam PF00005 ABC transporter 30 188 1.9E-24 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 SMART SM00382 318 510 3.3E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS26125 525b94ae9e07a1c8e70117c3be453002 554 SMART SM00382 38 238 6.5E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS04905 ab645e7ac9c147f953ce7a4eac36f9e8 308 Gene3D G3DSA:3.10.180.10 250 305 7.1E-4 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS04905 ab645e7ac9c147f953ce7a4eac36f9e8 308 Gene3D G3DSA:3.10.180.10 119 164 6.1E-4 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS04905 ab645e7ac9c147f953ce7a4eac36f9e8 308 SUPERFAMILY SSF54593 226 306 1.38E-7 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS04905 ab645e7ac9c147f953ce7a4eac36f9e8 308 SUPERFAMILY SSF54593 49 167 9.66E-7 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS07485 f7dcc7b41307ef83c6682f087df02fba 87 Pfam PF00550 Phosphopantetheine attachment site 8 76 6.2E-9 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS07485 f7dcc7b41307ef83c6682f087df02fba 87 Gene3D G3DSA:1.10.1200.10 4 79 3.1E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS07485 f7dcc7b41307ef83c6682f087df02fba 87 ProSitePatterns PS00012 Phosphopantetheine attachment site. 37 52 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS07485 f7dcc7b41307ef83c6682f087df02fba 87 SUPERFAMILY SSF47336 3 80 6.94E-9 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS20330 1e2253fdda7d8012eab08eeca953f1d9 230 Pfam PF07729 FCD domain 96 218 2.1E-25 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS20330 1e2253fdda7d8012eab08eeca953f1d9 230 PANTHER PTHR11751:SF385 26 112 5.5E-32 T 23-04-2016 DC74_RS20330 1e2253fdda7d8012eab08eeca953f1d9 230 SUPERFAMILY SSF48008 92 224 6.02E-30 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS20330 1e2253fdda7d8012eab08eeca953f1d9 230 SMART SM00895 96 220 1.9E-19 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS20330 1e2253fdda7d8012eab08eeca953f1d9 230 PANTHER PTHR11751 26 112 5.5E-32 T 23-04-2016 DC74_RS20330 1e2253fdda7d8012eab08eeca953f1d9 230 Gene3D G3DSA:1.10.10.10 18 86 2.8E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20330 1e2253fdda7d8012eab08eeca953f1d9 230 SUPERFAMILY SSF46785 20 90 8.44E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20330 1e2253fdda7d8012eab08eeca953f1d9 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 5.3E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS20330 1e2253fdda7d8012eab08eeca953f1d9 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 5.3E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS20330 1e2253fdda7d8012eab08eeca953f1d9 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 86 9.6E-17 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS20330 1e2253fdda7d8012eab08eeca953f1d9 230 Gene3D G3DSA:1.20.120.530 90 223 7.2E-32 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS20330 1e2253fdda7d8012eab08eeca953f1d9 230 SMART SM00345 28 86 1.1E-12 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS09905 2f60c88f66d8d0d0176fe3c531c70307 317 Pfam PF00696 Amino acid kinase family 28 273 5.7E-48 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 DC74_RS09905 2f60c88f66d8d0d0176fe3c531c70307 317 PIRSF PIRSF000728 13 296 4.9E-96 T 23-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09905 2f60c88f66d8d0d0176fe3c531c70307 317 PANTHER PTHR23342 7 296 8.3E-104 T 23-04-2016 DC74_RS09905 2f60c88f66d8d0d0176fe3c531c70307 317 Gene3D G3DSA:3.40.1160.10 26 295 1.9E-96 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 DC74_RS09905 2f60c88f66d8d0d0176fe3c531c70307 317 PRINTS PR00474 Glutamate 5-kinase family signature 59 73 4.3E-8 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 DC74_RS09905 2f60c88f66d8d0d0176fe3c531c70307 317 PRINTS PR00474 Glutamate 5-kinase family signature 246 266 4.3E-8 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 DC74_RS09905 2f60c88f66d8d0d0176fe3c531c70307 317 PRINTS PR00474 Glutamate 5-kinase family signature 195 222 4.3E-8 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 DC74_RS09905 2f60c88f66d8d0d0176fe3c531c70307 317 TIGRFAM TIGR00761 argB: acetylglutamate kinase 29 270 5.1E-71 T 23-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09905 2f60c88f66d8d0d0176fe3c531c70307 317 Hamap MF_00082_B Acetylglutamate kinase [argB]. 26 296 34.301 T 23-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09905 2f60c88f66d8d0d0176fe3c531c70307 317 SUPERFAMILY SSF53633 6 298 3.01E-84 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 PANTHER PTHR10909 285 721 4.3E-111 T 23-04-2016 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 575 716 1.7E-16 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 219 351 3.9E-21 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 Gene3D G3DSA:2.40.110.10 467 564 6.3E-33 T 23-04-2016 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 PANTHER PTHR10909:SF286 285 721 4.3E-111 T 23-04-2016 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 356 464 1.3E-11 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 103 3.5E-11 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 Gene3D G3DSA:1.10.540.10 4 105 4.9E-11 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 SUPERFAMILY SSF47203 576 718 1.27E-17 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 SUPERFAMILY SSF56645 362 588 5.89E-59 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 Gene3D G3DSA:1.10.540.10 362 464 2.6E-14 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 468 563 4.6E-21 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 Gene3D G3DSA:1.20.140.10 565 723 6.1E-28 T 23-04-2016 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 Gene3D G3DSA:1.20.140.10 218 352 5.1E-32 T 23-04-2016 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 SUPERFAMILY SSF47203 216 352 3.38E-32 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS13600 b940d503f6156b8fb53aa68df8e7e656 728 SUPERFAMILY SSF56645 1 205 1.11E-22 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS09205 813827883bddfa02110870010f4da079 90 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 6 89 4.7E-11 T 23-04-2016 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31|UniPathway: UPA00031 DC74_RS09205 813827883bddfa02110870010f4da079 90 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 3 90 19.266 T 23-04-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31|UniPathway: UPA00031 DC74_RS09205 813827883bddfa02110870010f4da079 90 SUPERFAMILY SSF101386 5 90 5.79E-21 T 23-04-2016 DC74_RS09205 813827883bddfa02110870010f4da079 90 PANTHER PTHR21256 5 90 8.6E-29 T 23-04-2016 DC74_RS09205 813827883bddfa02110870010f4da079 90 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 7 90 1.0E-24 T 23-04-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31|UniPathway: UPA00031 DC74_RS21950 ce7746296e67e4640176196472db052a 379 Gene3D G3DSA:3.30.360.10 164 348 5.6E-68 T 23-04-2016 DC74_RS21950 ce7746296e67e4640176196472db052a 379 SUPERFAMILY SSF55347 151 353 3.42E-60 T 23-04-2016 DC74_RS21950 ce7746296e67e4640176196472db052a 379 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 160 352 5.1E-42 T 23-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS21950 ce7746296e67e4640176196472db052a 379 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 27 135 1.1E-23 T 23-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DC74_RS21950 ce7746296e67e4640176196472db052a 379 SUPERFAMILY SSF51735 26 177 4.19E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS21950 ce7746296e67e4640176196472db052a 379 SMART SM00859 26 141 3.7E-25 T 23-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DC74_RS21950 ce7746296e67e4640176196472db052a 379 PANTHER PTHR10174:SF2 79 364 1.9E-50 T 23-04-2016 DC74_RS21950 ce7746296e67e4640176196472db052a 379 PANTHER PTHR10174 79 364 1.9E-50 T 23-04-2016 DC74_RS21950 ce7746296e67e4640176196472db052a 379 Gene3D G3DSA:3.40.50.720 25 163 2.8E-49 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS21950 ce7746296e67e4640176196472db052a 379 PIRSF PIRSF000148 24 371 3.9E-113 T 23-04-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS21950 ce7746296e67e4640176196472db052a 379 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 26 365 3.1E-105 T 23-04-2016 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS09650 195801352221d748e56b0b3fe55620d5 312 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 12 297 5.6E-60 T 23-04-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 DC74_RS09650 195801352221d748e56b0b3fe55620d5 312 PANTHER PTHR30606:SF2 17 300 1.1E-88 T 23-04-2016 DC74_RS09650 195801352221d748e56b0b3fe55620d5 312 PANTHER PTHR30606 17 300 1.1E-88 T 23-04-2016 DC74_RS20325 a3c4519e844f09f1aee306aa009836af 417 SUPERFAMILY SSF103473 4 403 1.57E-53 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS20325 a3c4519e844f09f1aee306aa009836af 417 PANTHER PTHR11662 18 404 6.4E-88 T 23-04-2016 DC74_RS20325 a3c4519e844f09f1aee306aa009836af 417 PANTHER PTHR11662:SF277 18 404 6.4E-88 T 23-04-2016 DC74_RS20325 a3c4519e844f09f1aee306aa009836af 417 Pfam PF07690 Major Facilitator Superfamily 10 286 6.4E-23 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS20325 a3c4519e844f09f1aee306aa009836af 417 Gene3D G3DSA:1.20.1250.20 8 183 2.7E-27 T 23-04-2016 DC74_RS20325 a3c4519e844f09f1aee306aa009836af 417 Gene3D G3DSA:1.20.1250.20 226 403 9.1E-13 T 23-04-2016 DC74_RS02315 b094b7c646a2a5e9e3d2bd0d578d0a0c 163 SUPERFAMILY SSF48498 74 150 8.45E-5 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS02315 b094b7c646a2a5e9e3d2bd0d578d0a0c 163 SUPERFAMILY SSF46689 3 73 1.54E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02315 b094b7c646a2a5e9e3d2bd0d578d0a0c 163 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 5.6E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS02315 b094b7c646a2a5e9e3d2bd0d578d0a0c 163 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 5.6E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS02315 b094b7c646a2a5e9e3d2bd0d578d0a0c 163 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 51 4.6E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS02315 b094b7c646a2a5e9e3d2bd0d578d0a0c 163 PANTHER PTHR30055 3 159 1.1E-32 T 23-04-2016 DC74_RS02315 b094b7c646a2a5e9e3d2bd0d578d0a0c 163 Gene3D G3DSA:1.10.357.10 3 157 2.3E-29 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS02315 b094b7c646a2a5e9e3d2bd0d578d0a0c 163 PANTHER PTHR30055:SF73 3 159 1.1E-32 T 23-04-2016 DC74_RS36725 46e2779e36da951686e3edc78c05c792 405 Gene3D G3DSA:3.90.1150.10 282 404 9.7E-24 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS36725 46e2779e36da951686e3edc78c05c792 405 Pfam PF00266 Aminotransferase class-V 39 397 2.9E-62 T 23-04-2016 IPR000192 Aminotransferase class V domain DC74_RS36725 46e2779e36da951686e3edc78c05c792 405 PANTHER PTHR11601 22 404 4.9E-71 T 23-04-2016 DC74_RS36725 46e2779e36da951686e3edc78c05c792 405 Gene3D G3DSA:3.40.640.10 49 281 1.0E-50 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS36725 46e2779e36da951686e3edc78c05c792 405 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 237 256 - T 23-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site DC74_RS36725 46e2779e36da951686e3edc78c05c792 405 SUPERFAMILY SSF53383 23 403 2.09E-75 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS13390 4face61260ca68c16eb53df2f68acecb 319 SMART SM01130 6 314 2.0E-79 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS13390 4face61260ca68c16eb53df2f68acecb 319 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 138 168 - T 23-04-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS13390 4face61260ca68c16eb53df2f68acecb 319 Gene3D G3DSA:3.20.20.70 5 315 1.3E-81 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS13390 4face61260ca68c16eb53df2f68acecb 319 PANTHER PTHR12128 5 316 7.2E-64 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS13390 4face61260ca68c16eb53df2f68acecb 319 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 4.7E-11 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS13390 4face61260ca68c16eb53df2f68acecb 319 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 4.7E-11 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS13390 4face61260ca68c16eb53df2f68acecb 319 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 4.7E-11 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS13390 4face61260ca68c16eb53df2f68acecb 319 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 4.7E-11 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS13390 4face61260ca68c16eb53df2f68acecb 319 PIRSF PIRSF001365 3 318 9.4E-74 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS13390 4face61260ca68c16eb53df2f68acecb 319 Pfam PF00701 Dihydrodipicolinate synthetase family 7 311 2.8E-49 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS13390 4face61260ca68c16eb53df2f68acecb 319 SUPERFAMILY SSF51569 3 315 7.12E-75 T 23-04-2016 DC74_RS10915 8741254b638678377d6dbea8d215baad 317 Gene3D G3DSA:3.40.190.10 154 258 1.1E-15 T 23-04-2016 DC74_RS10915 8741254b638678377d6dbea8d215baad 317 SUPERFAMILY SSF53850 68 302 1.09E-45 T 23-04-2016 DC74_RS10915 8741254b638678377d6dbea8d215baad 317 Gene3D G3DSA:3.40.190.10 74 153 2.8E-23 T 23-04-2016 DC74_RS10915 8741254b638678377d6dbea8d215baad 317 Gene3D G3DSA:3.40.190.10 263 300 2.8E-23 T 23-04-2016 DC74_RS10915 8741254b638678377d6dbea8d215baad 317 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 83 300 4.0E-39 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS10915 8741254b638678377d6dbea8d215baad 317 SMART SM00062 80 303 1.1E-26 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS35195 b3346d3ae3825799198830a3ab9aa580 254 Gene3D G3DSA:3.40.50.1000 11 28 2.6E-33 T 23-04-2016 IPR023214 HAD-like domain DC74_RS35195 b3346d3ae3825799198830a3ab9aa580 254 Gene3D G3DSA:3.40.50.1000 121 247 2.6E-33 T 23-04-2016 IPR023214 HAD-like domain DC74_RS35195 b3346d3ae3825799198830a3ab9aa580 254 PANTHER PTHR18901 14 249 1.0E-51 T 23-04-2016 DC74_RS35195 b3346d3ae3825799198830a3ab9aa580 254 Pfam PF00702 haloacid dehalogenase-like hydrolase 14 212 4.6E-13 T 23-04-2016 DC74_RS35195 b3346d3ae3825799198830a3ab9aa580 254 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 104 218 1.4E-13 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS35195 b3346d3ae3825799198830a3ab9aa580 254 PANTHER PTHR18901:SF19 14 249 1.0E-51 T 23-04-2016 DC74_RS35195 b3346d3ae3825799198830a3ab9aa580 254 SUPERFAMILY SSF56784 13 248 1.4E-39 T 23-04-2016 IPR023214 HAD-like domain DC74_RS07055 09c96e9b2220e948d30b4d100e633fa0 290 Gene3D G3DSA:3.30.465.10 59 177 6.1E-28 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS07055 09c96e9b2220e948d30b4d100e633fa0 290 SUPERFAMILY SSF56176 1 177 2.67E-46 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS07055 09c96e9b2220e948d30b4d100e633fa0 290 PANTHER PTHR11908 1 206 6.6E-42 T 23-04-2016 DC74_RS07055 09c96e9b2220e948d30b4d100e633fa0 290 Gene3D G3DSA:3.30.43.10 1 54 1.7E-21 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS07055 09c96e9b2220e948d30b4d100e633fa0 290 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 177 5.6E-41 T 23-04-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DC74_RS07055 09c96e9b2220e948d30b4d100e633fa0 290 PANTHER PTHR11908:SF68 1 206 6.6E-42 T 23-04-2016 DC74_RS28130 8b3fc450280de4b938c8426336100171 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.195 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28130 8b3fc450280de4b938c8426336100171 115 SUPERFAMILY SSF50104 1 114 2.51E-45 T 23-04-2016 IPR008991 Translation protein SH3-like domain DC74_RS28130 8b3fc450280de4b938c8426336100171 115 PANTHER PTHR15680 7 115 2.0E-50 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28130 8b3fc450280de4b938c8426336100171 115 PIRSF PIRSF002191 1 115 1.2E-48 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28130 8b3fc450280de4b938c8426336100171 115 Pfam PF01245 Ribosomal protein L19 3 112 1.8E-49 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28130 8b3fc450280de4b938c8426336100171 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 23-04-2016 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28130 8b3fc450280de4b938c8426336100171 115 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.1E-42 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28130 8b3fc450280de4b938c8426336100171 115 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.1E-42 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28130 8b3fc450280de4b938c8426336100171 115 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.1E-42 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28130 8b3fc450280de4b938c8426336100171 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 112 1.7E-48 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS40230 1ac4fa2f7ad5a9fd0bfb9c56db7248af 294 PANTHER PTHR10108:SF730 20 157 3.4E-12 T 23-04-2016 DC74_RS40230 1ac4fa2f7ad5a9fd0bfb9c56db7248af 294 Gene3D G3DSA:3.40.50.150 20 190 9.7E-18 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40230 1ac4fa2f7ad5a9fd0bfb9c56db7248af 294 PANTHER PTHR10108 20 157 3.4E-12 T 23-04-2016 DC74_RS40230 1ac4fa2f7ad5a9fd0bfb9c56db7248af 294 Pfam PF13649 Methyltransferase domain 58 148 1.3E-7 T 23-04-2016 DC74_RS40230 1ac4fa2f7ad5a9fd0bfb9c56db7248af 294 SMART SM00650 41 189 0.0024 T 23-04-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 DC74_RS40230 1ac4fa2f7ad5a9fd0bfb9c56db7248af 294 SUPERFAMILY SSF53335 20 212 3.66E-21 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS01055 e24a442615f15ad546c87586e6e03c6c 316 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 147 159 - T 23-04-2016 IPR033140 Lipase, GDXG, putative serine active site DC74_RS01055 e24a442615f15ad546c87586e6e03c6c 316 SUPERFAMILY SSF53474 53 305 2.36E-55 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01055 e24a442615f15ad546c87586e6e03c6c 316 PANTHER PTHR23024 79 306 1.5E-62 T 23-04-2016 DC74_RS01055 e24a442615f15ad546c87586e6e03c6c 316 Gene3D G3DSA:3.40.50.1820 21 305 7.8E-69 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01055 e24a442615f15ad546c87586e6e03c6c 316 PANTHER PTHR23024:SF47 79 306 1.5E-62 T 23-04-2016 DC74_RS01055 e24a442615f15ad546c87586e6e03c6c 316 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 79 95 - T 23-04-2016 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 DC74_RS01055 e24a442615f15ad546c87586e6e03c6c 316 Pfam PF07859 alpha/beta hydrolase fold 79 281 4.3E-58 T 23-04-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 DC74_RS23985 d85b371e040a7fe4a68c6498fc499200 219 Gene3D G3DSA:1.10.10.10 133 181 4.0E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23985 d85b371e040a7fe4a68c6498fc499200 219 Gene3D G3DSA:1.10.1740.10 11 113 8.3E-18 T 23-04-2016 DC74_RS23985 d85b371e040a7fe4a68c6498fc499200 219 Pfam PF08281 Sigma-70, region 4 134 178 3.3E-6 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS23985 d85b371e040a7fe4a68c6498fc499200 219 PANTHER PTHR30173 1 179 2.7E-47 T 23-04-2016 DC74_RS23985 d85b371e040a7fe4a68c6498fc499200 219 PANTHER PTHR30173:SF31 1 179 2.7E-47 T 23-04-2016 DC74_RS23985 d85b371e040a7fe4a68c6498fc499200 219 SUPERFAMILY SSF88946 10 94 1.41E-15 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS23985 d85b371e040a7fe4a68c6498fc499200 219 SUPERFAMILY SSF88659 128 180 2.06E-6 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS23985 d85b371e040a7fe4a68c6498fc499200 219 Pfam PF04542 Sigma-70 region 2 28 94 5.7E-13 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS23985 d85b371e040a7fe4a68c6498fc499200 219 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 179 1.1E-18 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS20575 f4b966cad61c37ba7cce0cbf4f530c40 248 TIGRFAM TIGR01076 sortase_fam: sortase 94 234 3.1E-13 T 23-04-2016 IPR005754 Sortase family DC74_RS20575 f4b966cad61c37ba7cce0cbf4f530c40 248 PANTHER PTHR33393 20 243 1.9E-60 T 23-04-2016 DC74_RS20575 f4b966cad61c37ba7cce0cbf4f530c40 248 Gene3D G3DSA:2.40.260.10 88 235 4.9E-26 T 23-04-2016 IPR023365 Sortase domain DC74_RS20575 f4b966cad61c37ba7cce0cbf4f530c40 248 PANTHER PTHR33393:SF3 20 243 1.9E-60 T 23-04-2016 DC74_RS20575 f4b966cad61c37ba7cce0cbf4f530c40 248 SUPERFAMILY SSF63817 87 236 3.53E-29 T 23-04-2016 IPR023365 Sortase domain DC74_RS20575 f4b966cad61c37ba7cce0cbf4f530c40 248 Pfam PF04203 Sortase family 96 232 3.5E-25 T 23-04-2016 IPR005754 Sortase family DC74_RS08625 f7bf3bffc675522ceeb80307b6d1c956 461 Gene3D G3DSA:3.40.190.10 181 376 5.7E-49 T 23-04-2016 DC74_RS08625 f7bf3bffc675522ceeb80307b6d1c956 461 Pfam PF01547 Bacterial extracellular solute-binding protein 61 352 8.1E-48 T 23-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 DC74_RS08625 f7bf3bffc675522ceeb80307b6d1c956 461 PANTHER PTHR30061:SF3 14 456 9.1E-137 T 23-04-2016 DC74_RS08625 f7bf3bffc675522ceeb80307b6d1c956 461 SUPERFAMILY SSF53850 45 453 2.57E-65 T 23-04-2016 DC74_RS08625 f7bf3bffc675522ceeb80307b6d1c956 461 PANTHER PTHR30061 14 456 9.1E-137 T 23-04-2016 DC74_RS08625 f7bf3bffc675522ceeb80307b6d1c956 461 Gene3D G3DSA:3.40.190.10 56 180 1.9E-18 T 23-04-2016 DC74_RS03700 6a517e2d5eebe8d8dadf4e8b81134cb3 116 Gene3D G3DSA:3.30.750.24 10 115 4.3E-25 T 23-04-2016 IPR002645 STAS domain DC74_RS03700 6a517e2d5eebe8d8dadf4e8b81134cb3 116 PANTHER PTHR33495 9 116 2.8E-14 T 23-04-2016 DC74_RS03700 6a517e2d5eebe8d8dadf4e8b81134cb3 116 PANTHER PTHR33495:SF2 9 116 2.8E-14 T 23-04-2016 DC74_RS03700 6a517e2d5eebe8d8dadf4e8b81134cb3 116 Pfam PF13466 STAS domain 20 99 1.5E-10 T 23-04-2016 IPR002645 STAS domain DC74_RS03700 6a517e2d5eebe8d8dadf4e8b81134cb3 116 SUPERFAMILY SSF52091 10 115 3.73E-18 T 23-04-2016 IPR002645 STAS domain DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 PANTHER PTHR10099:SF2 17 748 0.0 T 23-04-2016 DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 749 310.765 T 23-04-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 SUPERFAMILY SSF56042 209 439 2.99E-51 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 SUPERFAMILY SSF56042 582 747 2.84E-41 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 PIRSF PIRSF001587 7 749 7.6E-290 T 23-04-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 Pfam PF02769 AIR synthase related protein, C-terminal domain 585 722 5.4E-21 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 Pfam PF02769 AIR synthase related protein, C-terminal domain 211 366 6.4E-33 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 Gene3D G3DSA:3.30.1330.10 56 203 9.9E-54 T 23-04-2016 IPR016188 PurM-like, N-terminal domain DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 Gene3D G3DSA:3.30.1330.10 427 575 2.1E-53 T 23-04-2016 IPR016188 PurM-like, N-terminal domain DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 Pfam PF00586 AIR synthase related protein, N-terminal domain 96 198 9.5E-23 T 23-04-2016 IPR016188 PurM-like, N-terminal domain DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 Pfam PF00586 AIR synthase related protein, N-terminal domain 467 572 2.1E-23 T 23-04-2016 IPR016188 PurM-like, N-terminal domain DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 SUPERFAMILY SSF55326 410 578 6.02E-55 T 23-04-2016 DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 24 744 1.9E-263 T 23-04-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 PANTHER PTHR10099 17 748 0.0 T 23-04-2016 DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 Gene3D G3DSA:3.90.650.10 260 364 5.2E-4 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS19720 7cf58137591a5ab2273ad468cb17c565 749 SUPERFAMILY SSF55326 19 204 8.37E-50 T 23-04-2016 DC74_RS39210 ef21b00b5b0f4fdc294e00e467669a02 236 Gene3D G3DSA:3.40.50.2300 1 146 5.5E-45 T 23-04-2016 DC74_RS39210 ef21b00b5b0f4fdc294e00e467669a02 236 SUPERFAMILY SSF52172 1 182 1.05E-44 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS39210 ef21b00b5b0f4fdc294e00e467669a02 236 Pfam PF00072 Response regulator receiver domain 4 112 3.7E-32 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS39210 ef21b00b5b0f4fdc294e00e467669a02 236 Gene3D G3DSA:1.10.10.10 147 225 7.0E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39210 ef21b00b5b0f4fdc294e00e467669a02 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 7.8E-28 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS39210 ef21b00b5b0f4fdc294e00e467669a02 236 SMART SM00448 2 112 1.7E-49 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS39210 ef21b00b5b0f4fdc294e00e467669a02 236 PANTHER PTHR26402:SF292 2 226 4.7E-100 T 23-04-2016 DC74_RS39210 ef21b00b5b0f4fdc294e00e467669a02 236 SMART SM00862 147 222 7.2E-31 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS39210 ef21b00b5b0f4fdc294e00e467669a02 236 PANTHER PTHR26402 2 226 4.7E-100 T 23-04-2016 DC74_RS01755 08f346ddcb0b75d41740d99867c85a16 314 SUPERFAMILY SSF56281 60 301 2.49E-37 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS01755 08f346ddcb0b75d41740d99867c85a16 314 Pfam PF00753 Metallo-beta-lactamase superfamily 78 281 2.0E-20 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS01755 08f346ddcb0b75d41740d99867c85a16 314 PANTHER PTHR23200 17 284 9.2E-67 T 23-04-2016 DC74_RS01755 08f346ddcb0b75d41740d99867c85a16 314 Gene3D G3DSA:3.60.15.10 10 299 1.7E-46 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS01755 08f346ddcb0b75d41740d99867c85a16 314 SMART SM00849 70 281 5.9E-18 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS01755 08f346ddcb0b75d41740d99867c85a16 314 PANTHER PTHR23200:SF43 17 284 9.2E-67 T 23-04-2016 DC74_RS19485 1c1936539fd03e1466a56ee9e62fd7b8 80 Gene3D G3DSA:1.10.10.10 25 72 8.6E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19485 1c1936539fd03e1466a56ee9e62fd7b8 80 PANTHER PTHR38431 15 80 1.1E-30 T 23-04-2016 DC74_RS19485 1c1936539fd03e1466a56ee9e62fd7b8 80 Pfam PF12728 Helix-turn-helix domain 24 72 8.1E-14 T 23-04-2016 DC74_RS19485 1c1936539fd03e1466a56ee9e62fd7b8 80 SUPERFAMILY SSF46955 24 73 4.39E-5 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS19485 1c1936539fd03e1466a56ee9e62fd7b8 80 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 24 71 3.5E-20 T 23-04-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 DC74_RS04555 c11c9576eb745956b5695a9cce49ea43 210 Gene3D G3DSA:1.20.1550.10 27 115 1.9E-9 T 23-04-2016 IPR023380 Disulphide bond formation protein DsbB-like domain DC74_RS04555 c11c9576eb745956b5695a9cce49ea43 210 Pfam PF02600 Disulfide bond formation protein DsbB 26 115 1.5E-11 T 23-04-2016 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 DC74_RS04555 c11c9576eb745956b5695a9cce49ea43 210 SUPERFAMILY SSF158442 27 145 1.44E-17 T 23-04-2016 DC74_RS02125 87044f9eceee8a5cfa57b550e4aa7e46 204 PANTHER PTHR11019:SF25 5 165 4.0E-24 T 23-04-2016 DC74_RS02125 87044f9eceee8a5cfa57b550e4aa7e46 204 SUPERFAMILY SSF52317 1 189 9.36E-49 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS02125 87044f9eceee8a5cfa57b550e4aa7e46 204 Pfam PF01965 DJ-1/PfpI family 6 169 7.3E-29 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS02125 87044f9eceee8a5cfa57b550e4aa7e46 204 Gene3D G3DSA:3.40.50.880 5 201 4.5E-66 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS02125 87044f9eceee8a5cfa57b550e4aa7e46 204 PANTHER PTHR11019 5 165 4.0E-24 T 23-04-2016 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PRINTS PR00385 P450 superfamily signature 337 346 3.2E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PRINTS PR00385 P450 superfamily signature 270 281 3.2E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PRINTS PR00385 P450 superfamily signature 243 260 3.2E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PRINTS PR00385 P450 superfamily signature 346 357 3.2E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PANTHER PTHR24286 31 398 2.4E-87 T 23-04-2016 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 339 348 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 Gene3D G3DSA:1.10.630.10 17 398 3.2E-112 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PANTHER PTHR24286:SF42 31 398 2.4E-87 T 23-04-2016 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PRINTS PR00359 B-class P450 signature 147 163 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PRINTS PR00359 B-class P450 signature 100 111 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PRINTS PR00359 B-class P450 signature 316 331 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PRINTS PR00359 B-class P450 signature 288 315 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PRINTS PR00359 B-class P450 signature 201 223 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PRINTS PR00359 B-class P450 signature 337 346 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PRINTS PR00359 B-class P450 signature 164 179 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 PRINTS PR00359 B-class P450 signature 346 357 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 Pfam PF00067 Cytochrome P450 270 364 6.8E-20 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS38730 0f38c199781b5098d2403d826bfa4896 398 SUPERFAMILY SSF48264 8 397 6.94E-90 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37325 f32fd466146d0353aadb722a7edac8d0 282 Gene3D G3DSA:3.40.50.1820 6 277 1.4E-55 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS37325 f32fd466146d0353aadb722a7edac8d0 282 PANTHER PTHR10992 13 279 1.7E-43 T 23-04-2016 DC74_RS37325 f32fd466146d0353aadb722a7edac8d0 282 PANTHER PTHR10992:SF778 13 279 1.7E-43 T 23-04-2016 DC74_RS37325 f32fd466146d0353aadb722a7edac8d0 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 237 2.3E-8 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS37325 f32fd466146d0353aadb722a7edac8d0 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 2.3E-8 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS37325 f32fd466146d0353aadb722a7edac8d0 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 2.3E-8 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS37325 f32fd466146d0353aadb722a7edac8d0 282 SUPERFAMILY SSF53474 13 279 5.04E-57 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS37325 f32fd466146d0353aadb722a7edac8d0 282 PRINTS PR00412 Epoxide hydrolase signature 102 115 9.1E-8 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS37325 f32fd466146d0353aadb722a7edac8d0 282 PRINTS PR00412 Epoxide hydrolase signature 254 276 9.1E-8 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS37325 f32fd466146d0353aadb722a7edac8d0 282 PRINTS PR00412 Epoxide hydrolase signature 38 56 9.1E-8 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS37325 f32fd466146d0353aadb722a7edac8d0 282 Pfam PF00561 alpha/beta hydrolase fold 32 264 1.7E-22 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS17155 5cdbb87dda4d282cec4385bd07a44b1e 169 Pfam PF04138 GtrA-like protein 20 140 1.6E-22 T 23-04-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 SUPERFAMILY SSF63380 348 443 1.24E-23 T 23-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 PANTHER PTHR22924 210 576 2.0E-88 T 23-04-2016 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 Gene3D G3DSA:1.10.490.10 213 341 1.4E-39 T 23-04-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 Gene3D G3DSA:3.40.50.80 451 577 2.6E-25 T 23-04-2016 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 Gene3D G3DSA:2.40.30.10 348 444 5.7E-24 T 23-04-2016 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 SUPERFAMILY SSF46458 210 337 6.73E-31 T 23-04-2016 IPR009050 Globin-like DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 Pfam PF00042 Globin 211 304 2.1E-10 T 23-04-2016 IPR000971 Globin GO:0019825|GO:0020037 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 Pfam PF00175 Oxidoreductase NAD-binding domain 456 557 1.1E-10 T 23-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 PRINTS PR00410 Phenol hydroxylase reductase family signature 376 388 5.3E-15 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 PRINTS PR00410 Phenol hydroxylase reductase family signature 454 473 5.3E-15 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 PRINTS PR00410 Phenol hydroxylase reductase family signature 546 554 5.3E-15 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 PRINTS PR00410 Phenol hydroxylase reductase family signature 479 488 5.3E-15 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 SUPERFAMILY SSF52343 450 576 2.49E-24 T 23-04-2016 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 PANTHER PTHR22924:SF2 210 576 2.0E-88 T 23-04-2016 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 Pfam PF00970 Oxidoreductase FAD-binding domain 351 443 1.7E-11 T 23-04-2016 IPR008333 Oxidoreductase, FAD-binding domain DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 394 401 9.3E-5 T 23-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 454 473 9.3E-5 T 23-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 DC74_RS20920 33078920f52e436c09b5dcb8255e14d7 586 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 479 488 9.3E-5 T 23-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 DC74_RS27495 d5c53e41fffbda229749649d97f5a011 582 Gene3D G3DSA:3.40.190.10 231 340 3.0E-22 T 23-04-2016 DC74_RS27495 d5c53e41fffbda229749649d97f5a011 582 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 495 2.9E-65 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain DC74_RS27495 d5c53e41fffbda229749649d97f5a011 582 PIRSF PIRSF002741 6 577 1.4E-69 T 23-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DC74_RS27495 d5c53e41fffbda229749649d97f5a011 582 Gene3D G3DSA:3.90.76.10 61 230 1.5E-34 T 23-04-2016 DC74_RS27495 d5c53e41fffbda229749649d97f5a011 582 Gene3D G3DSA:3.10.105.10 341 549 1.6E-37 T 23-04-2016 DC74_RS27495 d5c53e41fffbda229749649d97f5a011 582 PANTHER PTHR30290 1 581 2.8E-103 T 23-04-2016 DC74_RS27495 d5c53e41fffbda229749649d97f5a011 582 SUPERFAMILY SSF53850 49 571 7.06E-91 T 23-04-2016 DC74_RS27495 d5c53e41fffbda229749649d97f5a011 582 PANTHER PTHR30290:SF31 1 581 2.8E-103 T 23-04-2016 DC74_RS23990 49575cd54cee3813eb98df9fcddb3bbe 124 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 111 4.4E-18 T 23-04-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 DC74_RS23990 49575cd54cee3813eb98df9fcddb3bbe 124 PANTHER PTHR33495 2 122 3.4E-31 T 23-04-2016 DC74_RS23990 49575cd54cee3813eb98df9fcddb3bbe 124 Pfam PF13466 STAS domain 16 80 1.2E-12 T 23-04-2016 IPR002645 STAS domain DC74_RS23990 49575cd54cee3813eb98df9fcddb3bbe 124 Gene3D G3DSA:3.30.750.24 4 117 2.8E-36 T 23-04-2016 IPR002645 STAS domain DC74_RS23990 49575cd54cee3813eb98df9fcddb3bbe 124 SUPERFAMILY SSF52091 5 116 7.26E-21 T 23-04-2016 IPR002645 STAS domain DC74_RS23990 49575cd54cee3813eb98df9fcddb3bbe 124 PANTHER PTHR33495:SF2 2 122 3.4E-31 T 23-04-2016 DC74_RS35310 0a5198700a66773a6acbc519dd414faf 207 PANTHER PTHR30055 1 206 1.0E-28 T 23-04-2016 DC74_RS35310 0a5198700a66773a6acbc519dd414faf 207 SUPERFAMILY SSF48498 90 203 1.1E-12 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS35310 0a5198700a66773a6acbc519dd414faf 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 1.3E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS35310 0a5198700a66773a6acbc519dd414faf 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.2E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS35310 0a5198700a66773a6acbc519dd414faf 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.2E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS35310 0a5198700a66773a6acbc519dd414faf 207 Gene3D G3DSA:1.10.357.10 18 199 1.3E-40 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS35310 0a5198700a66773a6acbc519dd414faf 207 SUPERFAMILY SSF46689 16 92 3.08E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 Gene3D G3DSA:3.40.50.720 7 273 1.5E-78 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 1.2E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 238 258 1.2E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 1.2E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.2E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 101 112 1.2E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 1.2E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 PANTHER PTHR24322 174 205 1.8E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 PANTHER PTHR24322 60 158 1.8E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 PANTHER PTHR24322 14 33 1.8E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 101 112 5.3E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 5.3E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 5.3E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 SUPERFAMILY SSF51735 9 274 8.55E-72 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 273 3.8E-49 T 23-04-2016 DC74_RS34425 7177222b3c82fa9f61adbeda1f36c7cf 275 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 210 6.2E-5 T 23-04-2016 DC74_RS25460 215320da05d8134b4fd010b7b8c9ed60 406 SUPERFAMILY SSF103473 3 383 2.22E-58 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS25460 215320da05d8134b4fd010b7b8c9ed60 406 Pfam PF07690 Major Facilitator Superfamily 9 323 3.3E-40 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS25460 215320da05d8134b4fd010b7b8c9ed60 406 PANTHER PTHR23501 1 386 2.3E-125 T 23-04-2016 DC74_RS25460 215320da05d8134b4fd010b7b8c9ed60 406 PANTHER PTHR23501:SF4 1 386 2.3E-125 T 23-04-2016 DC74_RS25460 215320da05d8134b4fd010b7b8c9ed60 406 Gene3D G3DSA:1.20.1250.20 202 384 9.3E-14 T 23-04-2016 DC74_RS25460 215320da05d8134b4fd010b7b8c9ed60 406 Gene3D G3DSA:1.20.1250.20 5 183 1.1E-28 T 23-04-2016 DC74_RS01810 c359e3a132606b3109cd244e7ad4d5d5 204 Pfam PF02669 K+-transporting ATPase, c chain 1 189 1.3E-62 T 23-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 DC74_RS01810 c359e3a132606b3109cd244e7ad4d5d5 204 PANTHER PTHR30042 1 51 4.8E-72 T 23-04-2016 DC74_RS01810 c359e3a132606b3109cd244e7ad4d5d5 204 PANTHER PTHR30042 67 198 4.8E-72 T 23-04-2016 DC74_RS01810 c359e3a132606b3109cd244e7ad4d5d5 204 PANTHER PTHR30042:SF2 1 51 4.8E-72 T 23-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 DC74_RS01810 c359e3a132606b3109cd244e7ad4d5d5 204 PANTHER PTHR30042:SF2 67 198 4.8E-72 T 23-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 DC74_RS01810 c359e3a132606b3109cd244e7ad4d5d5 204 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 1 188 5.6E-49 T 23-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 DC74_RS01810 c359e3a132606b3109cd244e7ad4d5d5 204 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 1 191 28.999 T 23-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 DC74_RS01810 c359e3a132606b3109cd244e7ad4d5d5 204 PIRSF PIRSF001296 1 194 7.5E-62 T 23-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 Gene3D G3DSA:3.40.50.20 2 93 8.6E-32 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 277 284 - T 23-04-2016 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 PANTHER PTHR10520 1 418 2.0E-214 T 23-04-2016 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 SMART SM01209 101 283 3.4E-114 T 23-04-2016 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 SUPERFAMILY SSF51246 316 414 2.15E-25 T 23-04-2016 IPR011054 Rudiment single hybrid motif DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 415 40.414 T 23-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 SUPERFAMILY SSF56059 102 307 2.65E-54 T 23-04-2016 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 Gene3D G3DSA:3.30.1490.20 122 178 1.2E-16 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 1.2E-28 T 23-04-2016 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 415 3.1E-141 T 23-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 283 5.5E-65 T 23-04-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 319 412 1.1E-26 T 23-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 SMART SM01210 318 415 1.7E-42 T 23-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 Gene3D G3DSA:3.90.600.10 318 414 2.2E-31 T 23-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 SUPERFAMILY SSF52440 2 101 2.88E-29 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS19780 433237adbaae6916f67371d2e7fa83c3 418 Gene3D G3DSA:3.30.470.20 179 316 1.5E-55 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS29370 17950b933265c9dbfcf4aedd193a077a 205 PANTHER PTHR30328 3 185 2.8E-40 T 23-04-2016 DC74_RS29370 17950b933265c9dbfcf4aedd193a077a 205 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS29370 17950b933265c9dbfcf4aedd193a077a 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 8.2E-18 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS29370 17950b933265c9dbfcf4aedd193a077a 205 SUPERFAMILY SSF48498 76 199 5.13E-25 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS29370 17950b933265c9dbfcf4aedd193a077a 205 SUPERFAMILY SSF46689 4 72 1.13E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS29370 17950b933265c9dbfcf4aedd193a077a 205 PANTHER PTHR30328:SF29 3 185 2.8E-40 T 23-04-2016 DC74_RS29370 17950b933265c9dbfcf4aedd193a077a 205 Gene3D G3DSA:1.10.357.10 3 187 4.4E-37 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS29370 17950b933265c9dbfcf4aedd193a077a 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 6.1E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS29370 17950b933265c9dbfcf4aedd193a077a 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 6.1E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34740 b7f4bc4d8ff3c3693b6d7fe2e74906c0 312 Pfam PF13411 MerR HTH family regulatory protein 7 75 8.4E-20 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS34740 b7f4bc4d8ff3c3693b6d7fe2e74906c0 312 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 2.2E-11 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS34740 b7f4bc4d8ff3c3693b6d7fe2e74906c0 312 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 2.2E-11 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS34740 b7f4bc4d8ff3c3693b6d7fe2e74906c0 312 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 2.2E-11 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS34740 b7f4bc4d8ff3c3693b6d7fe2e74906c0 312 Gene3D G3DSA:1.10.1660.10 7 110 2.5E-28 T 23-04-2016 DC74_RS34740 b7f4bc4d8ff3c3693b6d7fe2e74906c0 312 SMART SM00422 7 76 4.2E-26 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS34740 b7f4bc4d8ff3c3693b6d7fe2e74906c0 312 PANTHER PTHR30204 1 131 1.3E-21 T 23-04-2016 DC74_RS34740 b7f4bc4d8ff3c3693b6d7fe2e74906c0 312 SUPERFAMILY SSF46955 7 109 4.4E-25 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS38440 d26ec97002b6a7c61d39a6d86902b9d8 245 Pfam PF06197 Protein of unknown function (DUF998) 34 224 4.9E-15 T 23-04-2016 IPR009339 Protein of unknown function DUF998 DC74_RS05490 bfa77bec2a1c2b13fc61b295298ca308 277 Gene3D G3DSA:3.90.550.10 1 253 1.9E-41 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS05490 bfa77bec2a1c2b13fc61b295298ca308 277 PANTHER PTHR22572:SF24 2 259 2.0E-161 T 23-04-2016 DC74_RS05490 bfa77bec2a1c2b13fc61b295298ca308 277 SUPERFAMILY SSF53448 1 257 3.38E-40 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS05490 bfa77bec2a1c2b13fc61b295298ca308 277 PANTHER PTHR22572 2 259 2.0E-161 T 23-04-2016 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 Gene3D G3DSA:1.10.630.10 12 364 4.2E-69 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PANTHER PTHR11712 48 334 1.2E-36 T 23-04-2016 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 SUPERFAMILY SSF48264 14 363 3.41E-62 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 305 314 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PRINTS PR00385 P450 superfamily signature 237 248 1.4E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PRINTS PR00385 P450 superfamily signature 303 312 1.4E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PRINTS PR00385 P450 superfamily signature 312 323 1.4E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PRINTS PR00385 P450 superfamily signature 202 219 1.4E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 Pfam PF00067 Cytochrome P450 236 336 1.9E-20 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PRINTS PR00359 B-class P450 signature 99 115 7.3E-24 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PRINTS PR00359 B-class P450 signature 282 297 7.3E-24 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PRINTS PR00359 B-class P450 signature 303 312 7.3E-24 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PRINTS PR00359 B-class P450 signature 312 323 7.3E-24 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PRINTS PR00359 B-class P450 signature 254 281 7.3E-24 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PRINTS PR00359 B-class P450 signature 53 64 7.3E-24 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PRINTS PR00359 B-class P450 signature 237 248 7.3E-24 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04490 bb5b70101687c64577fe75d824cf3214 367 PANTHER PTHR11712:SF282 48 334 1.2E-36 T 23-04-2016 DC74_RS40660 3bc13601832fd339926f8d86b9c97df2 155 PANTHER PTHR35908:SF1 1 131 9.2E-19 T 23-04-2016 DC74_RS40660 3bc13601832fd339926f8d86b9c97df2 155 Gene3D G3DSA:3.10.180.10 4 121 3.5E-9 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS40660 3bc13601832fd339926f8d86b9c97df2 155 PANTHER PTHR35908 1 131 9.2E-19 T 23-04-2016 DC74_RS40660 3bc13601832fd339926f8d86b9c97df2 155 SUPERFAMILY SSF54593 4 116 6.73E-10 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS06695 d507bc1aa57d2766a04177f4e6b6dae0 361 Pfam PF00107 Zinc-binding dehydrogenase 190 319 3.1E-29 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS06695 d507bc1aa57d2766a04177f4e6b6dae0 361 SUPERFAMILY SSF50129 310 360 1.18E-6 T 23-04-2016 IPR011032 GroES-like DC74_RS06695 d507bc1aa57d2766a04177f4e6b6dae0 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 147 5.4E-27 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS06695 d507bc1aa57d2766a04177f4e6b6dae0 361 SUPERFAMILY SSF50129 4 186 2.13E-52 T 23-04-2016 IPR011032 GroES-like DC74_RS06695 d507bc1aa57d2766a04177f4e6b6dae0 361 Gene3D G3DSA:3.40.50.720 183 302 7.9E-42 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06695 d507bc1aa57d2766a04177f4e6b6dae0 361 SUPERFAMILY SSF51735 154 328 7.8E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06695 d507bc1aa57d2766a04177f4e6b6dae0 361 SMART SM00829 14 359 2.0E-4 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS06695 d507bc1aa57d2766a04177f4e6b6dae0 361 PANTHER PTHR11695 17 361 2.7E-204 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS06695 d507bc1aa57d2766a04177f4e6b6dae0 361 PANTHER PTHR11695:SF417 17 361 2.7E-204 T 23-04-2016 DC74_RS06695 d507bc1aa57d2766a04177f4e6b6dae0 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS06695 d507bc1aa57d2766a04177f4e6b6dae0 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 361 6.1E-196 T 23-04-2016 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 DC74_RS06695 d507bc1aa57d2766a04177f4e6b6dae0 361 Gene3D G3DSA:3.90.180.10 2 182 2.4E-55 T 23-04-2016 IPR011032 GroES-like DC74_RS38180 3576c040f5e40a13057492910be29c95 390 Gene3D G3DSA:3.50.50.60 284 322 1.3E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38180 3576c040f5e40a13057492910be29c95 390 Gene3D G3DSA:3.50.50.60 5 168 1.3E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38180 3576c040f5e40a13057492910be29c95 390 PANTHER PTHR13789 5 345 3.7E-66 T 23-04-2016 DC74_RS38180 3576c040f5e40a13057492910be29c95 390 SUPERFAMILY SSF51905 273 359 2.59E-54 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38180 3576c040f5e40a13057492910be29c95 390 SUPERFAMILY SSF51905 5 166 2.59E-54 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38180 3576c040f5e40a13057492910be29c95 390 Pfam PF01494 FAD binding domain 4 345 1.9E-23 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS38180 3576c040f5e40a13057492910be29c95 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 7.0E-18 T 23-04-2016 DC74_RS38180 3576c040f5e40a13057492910be29c95 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 7.0E-18 T 23-04-2016 DC74_RS38180 3576c040f5e40a13057492910be29c95 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 7.0E-18 T 23-04-2016 DC74_RS38180 3576c040f5e40a13057492910be29c95 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 145 160 7.0E-18 T 23-04-2016 DC74_RS38180 3576c040f5e40a13057492910be29c95 390 Gene3D G3DSA:3.50.50.60 239 247 7.6E-4 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38180 3576c040f5e40a13057492910be29c95 390 Gene3D G3DSA:3.50.50.60 169 190 7.6E-4 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35015 5aee28e41bc464201c3da1a7871e97fd 136 PANTHER PTHR33797 1 136 7.8E-57 T 23-04-2016 DC74_RS35015 5aee28e41bc464201c3da1a7871e97fd 136 PANTHER PTHR33797:SF2 1 136 7.8E-57 T 23-04-2016 DC74_RS35015 5aee28e41bc464201c3da1a7871e97fd 136 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 134 7.7E-48 T 23-04-2016 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 DC74_RS35015 5aee28e41bc464201c3da1a7871e97fd 136 SUPERFAMILY SSF82784 1 136 4.84E-40 T 23-04-2016 IPR003718 OsmC/Ohr family DC74_RS35015 5aee28e41bc464201c3da1a7871e97fd 136 Gene3D G3DSA:3.30.300.20 44 135 1.6E-34 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta DC74_RS35015 5aee28e41bc464201c3da1a7871e97fd 136 Pfam PF02566 OsmC-like protein 37 133 2.9E-19 T 23-04-2016 IPR003718 OsmC/Ohr family DC74_RS35015 5aee28e41bc464201c3da1a7871e97fd 136 Gene3D G3DSA:2.20.25.10 1 43 3.1E-16 T 23-04-2016 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 SMART SM00387 379 528 2.2E-34 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 380 527 9.6E-20 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 Gene3D G3DSA:3.30.565.10 326 412 1.8E-38 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 Gene3D G3DSA:3.30.565.10 453 527 1.8E-38 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 Pfam PF00512 His Kinase A (phospho-acceptor) domain 274 339 4.1E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 PANTHER PTHR24423 206 410 9.5E-64 T 23-04-2016 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 PANTHER PTHR24423 1 11 9.5E-64 T 23-04-2016 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 PANTHER PTHR24423 444 529 9.5E-64 T 23-04-2016 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 SUPERFAMILY SSF158472 214 262 2.48E-8 T 23-04-2016 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 SUPERFAMILY SSF55874 329 414 5.38E-34 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 SUPERFAMILY SSF55874 453 526 5.38E-34 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 SMART SM00388 272 339 1.1E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 SMART SM00304 212 264 6.6E-14 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 SUPERFAMILY SSF47384 256 339 4.12E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 Gene3D G3DSA:1.10.287.130 263 325 3.2E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 Pfam PF00672 HAMP domain 193 261 3.7E-14 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 506 7.8E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 482 7.8E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 525 7.8E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS24990 841547a7bb521527baab6c6b8c94bef6 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 468 7.8E-15 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS09680 57c32f04889269c4e4dea9ae4f18dab3 185 Gene3D G3DSA:3.30.428.10 45 183 2.9E-39 T 23-04-2016 IPR011146 HIT-like domain GO:0003824 DC74_RS09680 57c32f04889269c4e4dea9ae4f18dab3 185 SUPERFAMILY SSF54197 22 175 1.7E-42 T 23-04-2016 IPR011146 HIT-like domain GO:0003824 DC74_RS09680 57c32f04889269c4e4dea9ae4f18dab3 185 PANTHER PTHR23089:SF16 1 185 9.6E-99 T 23-04-2016 DC74_RS09680 57c32f04889269c4e4dea9ae4f18dab3 185 Pfam PF01230 HIT domain 60 151 1.6E-12 T 23-04-2016 IPR001310 Histidine triad (HIT) protein DC74_RS09680 57c32f04889269c4e4dea9ae4f18dab3 185 PANTHER PTHR23089 1 185 9.6E-99 T 23-04-2016 IPR001310 Histidine triad (HIT) protein DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 Gene3D G3DSA:1.20.1560.10 609 926 8.1E-34 T 23-04-2016 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 Gene3D G3DSA:1.20.1560.10 6 334 7.4E-44 T 23-04-2016 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 SUPERFAMILY SSF90123 609 925 4.71E-42 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 SUPERFAMILY SSF52540 340 554 3.18E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 PANTHER PTHR24221 18 459 3.7E-133 T 23-04-2016 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 16 553 8.0E-206 T 23-04-2016 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 SMART SM00382 965 1161 4.8E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 SMART SM00382 371 557 6.8E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 Gene3D G3DSA:3.40.50.300 345 557 6.9E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 Gene3D G3DSA:3.40.50.300 939 1174 9.9E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 SUPERFAMILY SSF90123 2 338 4.45E-52 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 SUPERFAMILY SSF52540 933 1183 7.66E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 PANTHER PTHR24221:SF261 1064 1184 3.7E-133 T 23-04-2016 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 PANTHER PTHR24221:SF261 18 459 3.7E-133 T 23-04-2016 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 PANTHER PTHR24221 1064 1184 3.7E-133 T 23-04-2016 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 609 1145 1.5E-190 T 23-04-2016 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 Pfam PF00005 ABC transporter 956 1114 3.6E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 Pfam PF00005 ABC transporter 365 511 1.3E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 ProSitePatterns PS00211 ABC transporters family signature. 483 497 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 ProSitePatterns PS00211 ABC transporters family signature. 1087 1101 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 Pfam PF00664 ABC transporter transmembrane region 665 874 1.2E-6 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS21020 8be948c685d4953f996a39fe573dec09 1185 Pfam PF00664 ABC transporter transmembrane region 19 286 3.3E-23 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS37185 41fa336125f29eaf2fa2c039b6fb72f8 237 Gene3D G3DSA:1.10.357.10 90 237 1.5E-33 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS37185 41fa336125f29eaf2fa2c039b6fb72f8 237 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 80 1.2E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37185 41fa336125f29eaf2fa2c039b6fb72f8 237 PANTHER PTHR30328 12 125 1.5E-19 T 23-04-2016 DC74_RS37185 41fa336125f29eaf2fa2c039b6fb72f8 237 SUPERFAMILY SSF46689 28 90 1.33E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS37185 41fa336125f29eaf2fa2c039b6fb72f8 237 PANTHER PTHR30328:SF17 12 125 1.5E-19 T 23-04-2016 DC74_RS37185 41fa336125f29eaf2fa2c039b6fb72f8 237 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 96 236 6.8E-14 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS37185 41fa336125f29eaf2fa2c039b6fb72f8 237 Gene3D G3DSA:1.10.10.60 24 89 2.9E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS37185 41fa336125f29eaf2fa2c039b6fb72f8 237 SUPERFAMILY SSF48498 101 236 5.0E-25 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS02115 c38f1561142b5d2d41f403b8ce3504ef 406 Gene3D G3DSA:3.40.50.720 133 151 1.7E-9 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02115 c38f1561142b5d2d41f403b8ce3504ef 406 Gene3D G3DSA:3.40.50.720 1 34 1.7E-9 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02115 c38f1561142b5d2d41f403b8ce3504ef 406 SUPERFAMILY SSF51905 279 351 3.11E-15 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02115 c38f1561142b5d2d41f403b8ce3504ef 406 SUPERFAMILY SSF51905 2 157 3.11E-15 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 Pfam PF08529 NusA N-terminal domain 66 103 6.3E-7 T 23-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 Pfam PF08529 NusA N-terminal domain 6 61 5.8E-9 T 23-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 SUPERFAMILY SSF54814 180 258 7.19E-28 T 23-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 Pfam PF13184 NusA-like KH domain 210 278 1.6E-26 T 23-04-2016 IPR025249 KH domain, NusA-like GO:0003723 DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 78 322 5.4E-99 T 23-04-2016 IPR010213 Transcription termination factor NusA GO:0003723 DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 Gene3D G3DSA:2.40.50.140 109 178 1.9E-24 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 330 25.979 T 23-04-2016 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 SUPERFAMILY SSF54814 259 324 9.16E-16 T 23-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 Gene3D G3DSA:3.30.300.20 179 257 1.6E-33 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 SMART SM00316 113 178 0.001 T 23-04-2016 IPR022967 RNA-binding domain, S1 DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 Gene3D G3DSA:3.30.1480.10 3 102 6.8E-30 T 23-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 Gene3D G3DSA:3.30.300.20 258 325 3.4E-30 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 SUPERFAMILY SSF50249 112 179 9.37E-15 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 SUPERFAMILY SSF69705 3 102 4.97E-27 T 23-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 PANTHER PTHR22648:SF0 1 320 3.8E-131 T 23-04-2016 DC74_RS28425 e9e11f0101446c13ad7158173428a3fa 330 PANTHER PTHR22648 1 320 3.8E-131 T 23-04-2016 DC74_RS36345 f30bfd9874edd5be5d259f48ba2a8e09 194 SUPERFAMILY SSF48498 77 191 1.13E-19 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS36345 f30bfd9874edd5be5d259f48ba2a8e09 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 8.7E-19 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS36345 f30bfd9874edd5be5d259f48ba2a8e09 194 Gene3D G3DSA:1.10.10.60 2 54 6.3E-22 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS36345 f30bfd9874edd5be5d259f48ba2a8e09 194 PANTHER PTHR30328:SF25 3 194 4.1E-40 T 23-04-2016 DC74_RS36345 f30bfd9874edd5be5d259f48ba2a8e09 194 PANTHER PTHR30328 3 194 4.1E-40 T 23-04-2016 DC74_RS36345 f30bfd9874edd5be5d259f48ba2a8e09 194 Gene3D G3DSA:1.10.357.10 55 191 2.4E-41 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS36345 f30bfd9874edd5be5d259f48ba2a8e09 194 SUPERFAMILY SSF46689 2 79 1.03E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS36345 f30bfd9874edd5be5d259f48ba2a8e09 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 2.7E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS36345 f30bfd9874edd5be5d259f48ba2a8e09 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 2.7E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS25185 69e9078c608051ea7dc1d257705bfa05 410 Pfam PF04892 VanZ like family 66 148 6.7E-13 T 23-04-2016 IPR006976 VanZ-like DC74_RS34705 f735d194866eaf8025a36d797784aca0 668 PANTHER PTHR13170:SF20 150 475 9.3E-91 T 23-04-2016 DC74_RS34705 f735d194866eaf8025a36d797784aca0 668 PANTHER PTHR13170 150 475 9.3E-91 T 23-04-2016 DC74_RS34705 f735d194866eaf8025a36d797784aca0 668 Gene3D G3DSA:3.30.379.10 49 198 2.3E-13 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like DC74_RS34705 f735d194866eaf8025a36d797784aca0 668 SUPERFAMILY SSF55545 54 200 4.71E-12 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like DC74_RS34705 f735d194866eaf8025a36d797784aca0 668 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 55 198 6.1E-13 T 23-04-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS34705 f735d194866eaf8025a36d797784aca0 668 Pfam PF07555 beta-N-acetylglucosaminidase 205 516 1.2E-102 T 23-04-2016 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 DC74_RS34705 f735d194866eaf8025a36d797784aca0 668 SUPERFAMILY SSF140657 538 667 2.01E-5 T 23-04-2016 DC74_RS34705 f735d194866eaf8025a36d797784aca0 668 SUPERFAMILY SSF51445 202 517 1.16E-95 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS38785 41c04fa2d2c412fb3014753a16dfad8d 244 Gene3D G3DSA:3.40.50.1360 69 197 2.7E-5 T 23-04-2016 DC74_RS38785 41c04fa2d2c412fb3014753a16dfad8d 244 Gene3D G3DSA:1.10.10.10 2 50 3.9E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38785 41c04fa2d2c412fb3014753a16dfad8d 244 SUPERFAMILY SSF100950 68 227 3.35E-20 T 23-04-2016 DC74_RS38785 41c04fa2d2c412fb3014753a16dfad8d 244 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 29 47 3.0E-9 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS38785 41c04fa2d2c412fb3014753a16dfad8d 244 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 15 29 3.0E-9 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS38785 41c04fa2d2c412fb3014753a16dfad8d 244 Pfam PF00455 DeoR C terminal sensor domain 67 223 1.4E-40 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain DC74_RS38785 41c04fa2d2c412fb3014753a16dfad8d 244 SUPERFAMILY SSF46785 2 50 1.3E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38785 41c04fa2d2c412fb3014753a16dfad8d 244 SMART SM00420 1 49 1.4E-9 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS38785 41c04fa2d2c412fb3014753a16dfad8d 244 PANTHER PTHR30363 1 244 7.3E-76 T 23-04-2016 DC74_RS38785 41c04fa2d2c412fb3014753a16dfad8d 244 SMART SM01134 64 225 1.3E-48 T 23-04-2016 DC74_RS38785 41c04fa2d2c412fb3014753a16dfad8d 244 PANTHER PTHR30363:SF1 1 244 7.3E-76 T 23-04-2016 DC74_RS38785 41c04fa2d2c412fb3014753a16dfad8d 244 Pfam PF08220 DeoR-like helix-turn-helix domain 1 47 8.5E-15 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS11065 7dece03745386868d36feceaf923617b 208 Gene3D G3DSA:3.90.79.10 9 184 2.5E-48 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS11065 7dece03745386868d36feceaf923617b 208 PANTHER PTHR11839 9 206 4.4E-82 T 23-04-2016 DC74_RS11065 7dece03745386868d36feceaf923617b 208 Pfam PF00293 NUDIX domain 48 162 2.3E-16 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS11065 7dece03745386868d36feceaf923617b 208 PANTHER PTHR11839:SF9 9 206 4.4E-82 T 23-04-2016 DC74_RS11065 7dece03745386868d36feceaf923617b 208 SUPERFAMILY SSF55811 9 182 2.03E-43 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 SUPERFAMILY SSF52317 13 202 2.6E-51 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 54 68 5.2E-6 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 13 27 5.2E-6 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 84 100 5.2E-6 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 209 528 2.9E-145 T 23-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 Pfam PF02540 NAD synthase 219 288 2.5E-7 T 23-04-2016 IPR022310 NAD/GMP synthase DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 SUPERFAMILY SSF52402 189 448 1.63E-55 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 Gene3D G3DSA:3.30.300.10 403 528 1.9E-48 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 Gene3D G3DSA:3.40.50.620 204 402 8.8E-56 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 13 195 9.0E-72 T 23-04-2016 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 PANTHER PTHR11922 11 525 9.8E-268 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 PRINTS PR00096 Glutamine amidotransferase superfamily signature 57 66 9.8E-8 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 PRINTS PR00096 Glutamine amidotransferase superfamily signature 173 186 9.8E-8 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 PRINTS PR00096 Glutamine amidotransferase superfamily signature 84 95 9.8E-8 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 PRINTS PR00097 Anthranilate synthase component II signature 173 186 8.3E-6 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 PRINTS PR00097 Anthranilate synthase component II signature 84 95 8.3E-6 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 PRINTS PR00097 Anthranilate synthase component II signature 57 66 8.3E-6 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 Gene3D G3DSA:3.40.50.880 12 195 1.4E-55 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 10 528 53.408 T 23-04-2016 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 Pfam PF00117 Glutamine amidotransferase class-I 15 195 1.4E-40 T 23-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 PANTHER PTHR11922:SF2 11 525 9.8E-268 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 SUPERFAMILY SSF54810 407 528 3.27E-46 T 23-04-2016 DC74_RS24050 ddc4cc2ebcb05616c9f48bcd20556ef8 528 Pfam PF00958 GMP synthase C terminal domain 435 527 3.9E-38 T 23-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 DC74_RS25295 f5fa8628f5875d84b5f225da1075f20a 594 Pfam PF13245 Part of AAA domain 27 100 5.4E-8 T 23-04-2016 DC74_RS25295 f5fa8628f5875d84b5f225da1075f20a 594 Pfam PF13361 UvrD-like helicase C-terminal domain 485 559 5.9E-6 T 23-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 DC74_RS25295 f5fa8628f5875d84b5f225da1075f20a 594 Gene3D G3DSA:3.40.50.300 456 564 9.8E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25295 f5fa8628f5875d84b5f225da1075f20a 594 SUPERFAMILY SSF52540 26 435 1.4E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25295 f5fa8628f5875d84b5f225da1075f20a 594 SUPERFAMILY SSF52540 486 560 1.4E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25295 f5fa8628f5875d84b5f225da1075f20a 594 Gene3D G3DSA:3.40.50.300 155 250 3.5E-26 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25295 f5fa8628f5875d84b5f225da1075f20a 594 Gene3D G3DSA:3.40.50.300 27 118 3.5E-26 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09725 2eefaee02dbae28a53e4153d96023542 188 PANTHER PTHR35525:SF1 5 188 6.3E-63 T 23-04-2016 DC74_RS09725 2eefaee02dbae28a53e4153d96023542 188 PANTHER PTHR35525 5 188 6.3E-63 T 23-04-2016 DC74_RS09725 2eefaee02dbae28a53e4153d96023542 188 Gene3D G3DSA:1.10.3300.10 3 185 1.1E-53 T 23-04-2016 IPR023286 ABATE domain DC74_RS09725 2eefaee02dbae28a53e4153d96023542 188 SUPERFAMILY SSF160904 2 182 1.44E-48 T 23-04-2016 DC74_RS09725 2eefaee02dbae28a53e4153d96023542 188 Pfam PF07336 Putative stress-induced transcription regulator 12 121 8.7E-14 T 23-04-2016 IPR010852 Putative stress-induced transcription regulator DC74_RS09725 2eefaee02dbae28a53e4153d96023542 188 Pfam PF11706 CGNR zinc finger 140 183 3.9E-18 T 23-04-2016 IPR021005 Zinc finger, CGNR DC74_RS37085 95f9133cd53720af2f1aa1a69ffb2771 452 Gene3D G3DSA:3.40.50.980 144 297 1.3E-21 T 23-04-2016 DC74_RS37085 95f9133cd53720af2f1aa1a69ffb2771 452 Pfam PF00501 AMP-binding enzyme 135 371 1.1E-27 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS37085 95f9133cd53720af2f1aa1a69ffb2771 452 Gene3D G3DSA:3.40.50.980 35 143 1.4E-7 T 23-04-2016 DC74_RS37085 95f9133cd53720af2f1aa1a69ffb2771 452 PANTHER PTHR24096 38 327 1.3E-23 T 23-04-2016 DC74_RS37085 95f9133cd53720af2f1aa1a69ffb2771 452 PANTHER PTHR24096 347 390 1.3E-23 T 23-04-2016 DC74_RS37085 95f9133cd53720af2f1aa1a69ffb2771 452 SUPERFAMILY SSF56801 34 449 9.16E-58 T 23-04-2016 DC74_RS00180 c236af5ed10564417742cb3c02fba961 428 TIGRFAM TIGR02679 TIGR02679: TIGR02679 family protein 38 418 4.1E-136 T 23-04-2016 IPR013495 Conserved hypothetical protein CHP02679 DC74_RS00180 c236af5ed10564417742cb3c02fba961 428 Pfam PF09664 Protein of unknown function C-terminus (DUF2399) 266 418 1.4E-47 T 23-04-2016 IPR024465 Domain of unknown function DUF2399 DC74_RS00180 c236af5ed10564417742cb3c02fba961 428 Pfam PF11796 Protein of unknown function N-terminus (DUF3323) 43 244 3.8E-49 T 23-04-2016 IPR024466 Conserved hypothetical protein CHP02679, N terminus DC74_RS04315 1e93f92afe19c4b8c68b252b8479d3f8 433 PANTHER PTHR11911:SF23 272 402 1.1E-18 T 23-04-2016 DC74_RS04315 1e93f92afe19c4b8c68b252b8479d3f8 433 Pfam PF00571 CBS domain 349 399 1.5E-9 T 23-04-2016 IPR000644 CBS domain DC74_RS04315 1e93f92afe19c4b8c68b252b8479d3f8 433 SMART SM00924 175 280 1.7E-23 T 23-04-2016 IPR006668 Magnesium transporter, MgtE intracellular domain DC74_RS04315 1e93f92afe19c4b8c68b252b8479d3f8 433 Gene3D G3DSA:3.10.580.10 278 400 1.7E-19 T 23-04-2016 DC74_RS04315 1e93f92afe19c4b8c68b252b8479d3f8 433 PANTHER PTHR11911 272 402 1.1E-18 T 23-04-2016 DC74_RS04315 1e93f92afe19c4b8c68b252b8479d3f8 433 Pfam PF03448 MgtE intracellular N domain 175 276 4.7E-21 T 23-04-2016 IPR006668 Magnesium transporter, MgtE intracellular domain DC74_RS04315 1e93f92afe19c4b8c68b252b8479d3f8 433 Gene3D G3DSA:1.25.60.10 150 274 4.3E-24 T 23-04-2016 DC74_RS04315 1e93f92afe19c4b8c68b252b8479d3f8 433 SUPERFAMILY SSF158791 150 276 7.72E-22 T 23-04-2016 DC74_RS04315 1e93f92afe19c4b8c68b252b8479d3f8 433 SUPERFAMILY SSF54631 280 404 1.83E-25 T 23-04-2016 DC74_RS04315 1e93f92afe19c4b8c68b252b8479d3f8 433 SMART SM00116 352 400 8.9E-6 T 23-04-2016 IPR000644 CBS domain DC74_RS04315 1e93f92afe19c4b8c68b252b8479d3f8 433 SMART SM00116 287 341 82.0 T 23-04-2016 IPR000644 CBS domain DC74_RS16865 d1e2d7b893ab81e4c7b01288ed07c796 631 Gene3D G3DSA:2.120.10.30 404 625 1.4E-9 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS16865 d1e2d7b893ab81e4c7b01288ed07c796 631 SMART SM00909 242 337 4.8E-4 T 23-04-2016 IPR019606 GerMN domain DC74_RS16865 d1e2d7b893ab81e4c7b01288ed07c796 631 SUPERFAMILY SSF63829 402 625 4.05E-8 T 23-04-2016 DC74_RS16865 d1e2d7b893ab81e4c7b01288ed07c796 631 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 371 630 1.2E-43 T 23-04-2016 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 Pfam PF00072 Response regulator receiver domain 1 107 6.4E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 PANTHER PTHR26402:SF151 1 203 4.3E-57 T 23-04-2016 DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 1.2E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 Gene3D G3DSA:3.40.50.2300 1 149 8.6E-32 T 23-04-2016 DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 SMART SM00448 1 110 1.9E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 SUPERFAMILY SSF52172 1 167 1.41E-29 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 SMART SM00421 146 203 1.7E-18 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 Gene3D G3DSA:1.10.10.10 150 205 5.0E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 5.0E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 5.0E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 5.0E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01525 f4f77afb0b5374090ab88cec91c8cbdd 231 PANTHER PTHR26402 1 203 4.3E-57 T 23-04-2016 DC74_RS05080 885565b24f4756bdbdc86666e140a3e2 359 SUPERFAMILY SSF53807 47 356 2.67E-37 T 23-04-2016 DC74_RS05080 885565b24f4756bdbdc86666e140a3e2 359 Gene3D G3DSA:3.40.50.1980 210 355 4.5E-25 T 23-04-2016 DC74_RS05080 885565b24f4756bdbdc86666e140a3e2 359 Gene3D G3DSA:3.40.50.1980 46 123 3.6E-7 T 23-04-2016 DC74_RS05080 885565b24f4756bdbdc86666e140a3e2 359 PANTHER PTHR30535 45 355 2.6E-32 T 23-04-2016 DC74_RS05080 885565b24f4756bdbdc86666e140a3e2 359 Pfam PF01497 Periplasmic binding protein 66 332 3.1E-21 T 23-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 DC74_RS04430 7cf70306c5aea641a5247d2fe9646f39 190 Gene3D G3DSA:1.10.10.10 101 184 3.4E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04430 7cf70306c5aea641a5247d2fe9646f39 190 PANTHER PTHR10815:SF5 23 184 5.9E-38 T 23-04-2016 DC74_RS04430 7cf70306c5aea641a5247d2fe9646f39 190 SUPERFAMILY SSF53155 23 107 3.1E-13 T 23-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 DC74_RS04430 7cf70306c5aea641a5247d2fe9646f39 190 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 23 97 7.1E-5 T 23-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 DC74_RS04430 7cf70306c5aea641a5247d2fe9646f39 190 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 102 182 1.6E-24 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS04430 7cf70306c5aea641a5247d2fe9646f39 190 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 104 183 9.1E-26 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS04430 7cf70306c5aea641a5247d2fe9646f39 190 PANTHER PTHR10815 23 184 5.9E-38 T 23-04-2016 DC74_RS04430 7cf70306c5aea641a5247d2fe9646f39 190 SUPERFAMILY SSF46767 101 184 7.72E-25 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS30845 3556365b0390ad2c36bc7a2a92994aef 311 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 20 311 2.0E-138 T 23-04-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 DC74_RS30845 3556365b0390ad2c36bc7a2a92994aef 311 PANTHER PTHR23293:SF6 17 167 2.4E-74 T 23-04-2016 DC74_RS30845 3556365b0390ad2c36bc7a2a92994aef 311 PANTHER PTHR23293 17 167 2.4E-74 T 23-04-2016 DC74_RS30845 3556365b0390ad2c36bc7a2a92994aef 311 PANTHER PTHR23293:SF6 187 220 2.4E-74 T 23-04-2016 DC74_RS30845 3556365b0390ad2c36bc7a2a92994aef 311 PANTHER PTHR23293:SF6 253 311 2.4E-74 T 23-04-2016 DC74_RS30845 3556365b0390ad2c36bc7a2a92994aef 311 PANTHER PTHR23293 187 220 2.4E-74 T 23-04-2016 DC74_RS30845 3556365b0390ad2c36bc7a2a92994aef 311 PANTHER PTHR23293 253 311 2.4E-74 T 23-04-2016 DC74_RS30845 3556365b0390ad2c36bc7a2a92994aef 311 PIRSF PIRSF002936 11 311 2.8E-137 T 23-04-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 DC74_RS30845 3556365b0390ad2c36bc7a2a92994aef 311 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 41 265 1.7E-47 T 23-04-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 DC74_RS30845 3556365b0390ad2c36bc7a2a92994aef 311 SUPERFAMILY SSF52402 16 218 3.26E-63 T 23-04-2016 DC74_RS30845 3556365b0390ad2c36bc7a2a92994aef 311 Gene3D G3DSA:3.40.50.620 14 219 3.1E-52 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS30845 3556365b0390ad2c36bc7a2a92994aef 311 Gene3D G3DSA:3.40.50.620 252 260 3.1E-52 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS28220 908c37984f35f4217afe8ff0b7659abe 358 Pfam PF13343 Bacterial extracellular solute-binding protein 84 321 1.1E-21 T 23-04-2016 DC74_RS28220 908c37984f35f4217afe8ff0b7659abe 358 Gene3D G3DSA:3.40.190.10 139 287 2.7E-22 T 23-04-2016 DC74_RS28220 908c37984f35f4217afe8ff0b7659abe 358 SUPERFAMILY SSF53850 32 353 2.27E-54 T 23-04-2016 DC74_RS28220 908c37984f35f4217afe8ff0b7659abe 358 Gene3D G3DSA:3.40.190.10 288 348 1.2E-30 T 23-04-2016 DC74_RS28220 908c37984f35f4217afe8ff0b7659abe 358 Gene3D G3DSA:3.40.190.10 5 133 1.2E-30 T 23-04-2016 DC74_RS28220 908c37984f35f4217afe8ff0b7659abe 358 PANTHER PTHR30006 25 356 3.2E-89 T 23-04-2016 DC74_RS28220 908c37984f35f4217afe8ff0b7659abe 358 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 35 352 8.1E-66 T 23-04-2016 IPR005948 Thiamine ABC transporter periplasmic binding protein GO:0005215|GO:0006810|GO:0015888|GO:0030288|GO:0030975 DC74_RS28220 908c37984f35f4217afe8ff0b7659abe 358 PANTHER PTHR30006:SF3 25 356 3.2E-89 T 23-04-2016 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 SUPERFAMILY SSF48264 32 349 4.19E-83 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 291 300 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PANTHER PTHR11712 27 349 1.0E-81 T 23-04-2016 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00385 P450 superfamily signature 289 298 1.4E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00385 P450 superfamily signature 221 232 1.4E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00385 P450 superfamily signature 184 201 1.4E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00385 P450 superfamily signature 298 309 1.4E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00359 B-class P450 signature 138 160 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00359 B-class P450 signature 267 282 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00359 B-class P450 signature 298 309 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00359 B-class P450 signature 101 116 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00359 B-class P450 signature 289 298 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00359 B-class P450 signature 84 100 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00359 B-class P450 signature 221 232 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00359 B-class P450 signature 37 48 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 PRINTS PR00359 B-class P450 signature 239 266 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 Pfam PF00067 Cytochrome P450 221 319 5.5E-21 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 Pfam PF00067 Cytochrome P450 122 207 3.0E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS39765 d35bc4ec5fe049c95fc64dc258a848cd 349 Gene3D G3DSA:1.10.630.10 1 349 1.8E-104 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS25140 f6ed814b34c822f82d5a0ed266f2ab73 407 SUPERFAMILY SSF55073 219 353 6.91E-31 T 23-04-2016 IPR029787 Nucleotide cyclase DC74_RS25140 f6ed814b34c822f82d5a0ed266f2ab73 407 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 220 345 1.9E-13 T 23-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 DC74_RS25140 f6ed814b34c822f82d5a0ed266f2ab73 407 SMART SM00044 106 359 1.8E-4 T 23-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 DC74_RS25140 f6ed814b34c822f82d5a0ed266f2ab73 407 Gene3D G3DSA:3.30.70.1230 220 349 4.2E-20 T 23-04-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 DC74_RS25140 f6ed814b34c822f82d5a0ed266f2ab73 407 Pfam PF16701 Adenylate cyclase regulatory domain 70 197 5.3E-8 T 23-04-2016 IPR032026 Adenylate cyclase regulatory domain DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 SMART SM00304 218 271 1.3E-4 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 424 2.0E-16 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 438 2.0E-16 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 482 2.0E-16 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 2.0E-16 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 PANTHER PTHR24423:SF399 75 146 4.1E-90 T 23-04-2016 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 PANTHER PTHR24423:SF399 212 485 4.1E-90 T 23-04-2016 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 SUPERFAMILY SSF158472 218 268 1.44E-5 T 23-04-2016 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 SUPERFAMILY SSF47384 255 334 1.37E-12 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 SUPERFAMILY SSF55874 323 487 2.62E-37 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 377 483 7.7E-22 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 SMART SM00387 374 485 4.6E-34 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 Gene3D G3DSA:1.10.287.130 264 320 3.5E-10 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 PANTHER PTHR24423 75 146 4.1E-90 T 23-04-2016 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 PANTHER PTHR24423 212 485 4.1E-90 T 23-04-2016 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 Pfam PF00672 HAMP domain 199 267 4.1E-12 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 Pfam PF00512 His Kinase A (phospho-acceptor) domain 273 333 6.2E-9 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 SMART SM00388 272 333 2.3E-10 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS03810 ef24088ffb88b08a38d4112bb901c57e 495 Gene3D G3DSA:3.30.565.10 321 486 3.6E-38 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS34885 0e25cb09ac67e26ec22e16c4177f4fd2 301 Gene3D G3DSA:3.40.50.720 194 269 6.5E-4 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS34885 0e25cb09ac67e26ec22e16c4177f4fd2 301 PANTHER PTHR10459 101 255 2.1E-12 T 23-04-2016 DC74_RS34885 0e25cb09ac67e26ec22e16c4177f4fd2 301 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 13 255 2.1E-80 T 23-04-2016 IPR014145 DNA ligase D, polymerase domain DC74_RS34885 0e25cb09ac67e26ec22e16c4177f4fd2 301 PANTHER PTHR10459:SF36 101 255 2.1E-12 T 23-04-2016 DC74_RS32355 93bffb0bba58c4ba17be0538a513408b 436 PANTHER PTHR30244 277 435 1.4E-138 T 23-04-2016 DC74_RS32355 93bffb0bba58c4ba17be0538a513408b 436 PANTHER PTHR30244:SF11 277 435 1.4E-138 T 23-04-2016 DC74_RS32355 93bffb0bba58c4ba17be0538a513408b 436 PANTHER PTHR30244:SF11 26 249 1.4E-138 T 23-04-2016 DC74_RS32355 93bffb0bba58c4ba17be0538a513408b 436 PIRSF PIRSF000390 31 436 2.4E-100 T 23-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase DC74_RS32355 93bffb0bba58c4ba17be0538a513408b 436 Gene3D G3DSA:3.40.640.10 38 304 3.1E-68 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS32355 93bffb0bba58c4ba17be0538a513408b 436 PANTHER PTHR30244 26 249 1.4E-138 T 23-04-2016 DC74_RS32355 93bffb0bba58c4ba17be0538a513408b 436 Gene3D G3DSA:3.90.1150.10 305 429 1.6E-46 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS32355 93bffb0bba58c4ba17be0538a513408b 436 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 45 429 7.9E-94 T 23-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase DC74_RS32355 93bffb0bba58c4ba17be0538a513408b 436 SUPERFAMILY SSF53383 39 433 1.43E-94 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS24460 112b96ff281d87b2f02db4cd0166e862 174 Gene3D G3DSA:2.40.50.230 15 85 6.0E-10 T 23-04-2016 IPR006531 Gp5 N-terminal DC74_RS24460 112b96ff281d87b2f02db4cd0166e862 174 SUPERFAMILY SSF69255 9 85 1.12E-16 T 23-04-2016 DC74_RS16530 e1f60858e1019c827f1d22290edd893f 213 Gene3D G3DSA:3.30.450.40 80 146 5.4E-13 T 23-04-2016 IPR029016 GAF domain-like DC74_RS16530 e1f60858e1019c827f1d22290edd893f 213 SUPERFAMILY SSF55781 67 212 3.01E-19 T 23-04-2016 IPR029016 GAF domain-like DC74_RS16530 e1f60858e1019c827f1d22290edd893f 213 SMART SM00346 6 93 8.4E-17 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS16530 e1f60858e1019c827f1d22290edd893f 213 PANTHER PTHR30136 4 212 2.0E-48 T 23-04-2016 DC74_RS16530 e1f60858e1019c827f1d22290edd893f 213 Gene3D G3DSA:3.30.450.40 150 212 3.8E-7 T 23-04-2016 IPR029016 GAF domain-like DC74_RS16530 e1f60858e1019c827f1d22290edd893f 213 Gene3D G3DSA:1.10.10.10 5 76 1.6E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16530 e1f60858e1019c827f1d22290edd893f 213 SUPERFAMILY SSF46785 7 76 3.1E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16530 e1f60858e1019c827f1d22290edd893f 213 PANTHER PTHR30136:SF14 4 212 2.0E-48 T 23-04-2016 DC74_RS16530 e1f60858e1019c827f1d22290edd893f 213 Pfam PF09339 IclR helix-turn-helix domain 8 58 1.0E-14 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 70 293 1.7E-32 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 Gene3D G3DSA:1.10.10.10 242 293 3.8E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 PANTHER PTHR30385 45 298 2.0E-102 T 23-04-2016 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 PANTHER PTHR30385:SF4 45 298 2.0E-102 T 23-04-2016 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 Pfam PF04542 Sigma-70 region 2 73 145 3.9E-17 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 67 294 3.3E-88 T 23-04-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 Pfam PF04539 Sigma-70 region 3 155 223 9.2E-9 T 23-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 PRINTS PR00046 Major sigma-70 factor signature 248 260 5.3E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 PRINTS PR00046 Major sigma-70 factor signature 265 280 5.3E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 PRINTS PR00046 Major sigma-70 factor signature 100 113 5.3E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 Pfam PF04545 Sigma-70, region 4 246 292 2.5E-15 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 100 113 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 SUPERFAMILY SSF88946 41 145 6.93E-31 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 Gene3D G3DSA:1.10.601.10 55 142 3.2E-25 T 23-04-2016 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 Gene3D G3DSA:1.10.10.10 144 199 3.5E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 SUPERFAMILY SSF88659 212 296 8.78E-16 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37935 6b3671cf1502b4620869fd3c422382aa 299 SUPERFAMILY SSF88659 149 227 3.4E-14 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS09240 0642387de9723016d488c85ae7839e2c 415 Gene3D G3DSA:3.30.420.40 235 380 8.5E-32 T 23-04-2016 DC74_RS09240 0642387de9723016d488c85ae7839e2c 415 PANTHER PTHR18964 70 409 1.5E-59 T 23-04-2016 DC74_RS09240 0642387de9723016d488c85ae7839e2c 415 Pfam PF12802 MarR family 25 76 1.9E-7 T 23-04-2016 DC74_RS09240 0642387de9723016d488c85ae7839e2c 415 SUPERFAMILY SSF53067 92 408 1.14E-35 T 23-04-2016 DC74_RS09240 0642387de9723016d488c85ae7839e2c 415 PANTHER PTHR18964:SF108 70 409 1.5E-59 T 23-04-2016 DC74_RS09240 0642387de9723016d488c85ae7839e2c 415 SUPERFAMILY SSF46785 21 83 5.91E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09240 0642387de9723016d488c85ae7839e2c 415 Pfam PF00480 ROK family 94 403 7.7E-28 T 23-04-2016 IPR000600 ROK family DC74_RS09240 0642387de9723016d488c85ae7839e2c 415 Gene3D G3DSA:3.30.420.40 88 234 1.4E-24 T 23-04-2016 DC74_RS09240 0642387de9723016d488c85ae7839e2c 415 Gene3D G3DSA:1.10.10.10 19 84 6.3E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36445 8142b376c4ef1f50a5cc8e1c2e538d9e 294 Gene3D G3DSA:3.10.129.10 153 292 2.5E-36 T 23-04-2016 IPR029069 HotDog domain DC74_RS36445 8142b376c4ef1f50a5cc8e1c2e538d9e 294 Pfam PF01575 MaoC like domain 170 265 6.0E-23 T 23-04-2016 IPR002539 MaoC-like domain DC74_RS36445 8142b376c4ef1f50a5cc8e1c2e538d9e 294 SUPERFAMILY SSF54637 19 166 1.86E-38 T 23-04-2016 IPR029069 HotDog domain DC74_RS36445 8142b376c4ef1f50a5cc8e1c2e538d9e 294 SUPERFAMILY SSF54637 169 290 1.15E-27 T 23-04-2016 IPR029069 HotDog domain DC74_RS36445 8142b376c4ef1f50a5cc8e1c2e538d9e 294 Gene3D G3DSA:3.10.129.10 5 152 8.9E-44 T 23-04-2016 IPR029069 HotDog domain DC74_RS36445 8142b376c4ef1f50a5cc8e1c2e538d9e 294 Pfam PF13452 N-terminal half of MaoC dehydratase 20 144 9.0E-14 T 23-04-2016 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 Gene3D G3DSA:3.30.70.370 520 610 1.5E-19 T 23-04-2016 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 Gene3D G3DSA:3.30.70.370 368 414 1.5E-19 T 23-04-2016 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 SUPERFAMILY SSF53098 19 231 5.36E-17 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 Gene3D G3DSA:1.20.1060.10 240 367 2.9E-8 T 23-04-2016 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 Gene3D G3DSA:3.30.420.10 26 237 1.7E-13 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 PRINTS PR00868 DNA-polymerase family A (pol I) signature 453 478 3.3E-11 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 PRINTS PR00868 DNA-polymerase family A (pol I) signature 432 445 3.3E-11 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 PRINTS PR00868 DNA-polymerase family A (pol I) signature 490 501 3.3E-11 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 PRINTS PR00868 DNA-polymerase family A (pol I) signature 360 382 3.3E-11 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 Gene3D G3DSA:1.10.150.20 415 519 2.4E-23 T 23-04-2016 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 Pfam PF01612 3'-5' exonuclease 23 213 5.8E-14 T 23-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 PANTHER PTHR10133 98 619 2.0E-56 T 23-04-2016 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 SMART SM00474 19 215 2.3E-14 T 23-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 SUPERFAMILY SSF56672 221 605 2.67E-70 T 23-04-2016 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 SMART SM00482 388 578 1.2E-32 T 23-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 Pfam PF00476 DNA polymerase family A 258 611 1.4E-47 T 23-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS24130 6a6d6960f437e5c7b0c1d8f20180fb21 625 PANTHER PTHR10133:SF27 98 619 2.0E-56 T 23-04-2016 DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 SUPERFAMILY SSF51735 6 245 3.61E-71 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 2.7E-58 T 23-04-2016 DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 181 1.5E-5 T 23-04-2016 DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 9.1E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 9.1E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 Gene3D G3DSA:3.40.50.720 2 245 5.5E-75 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.6E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.6E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.6E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.6E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.6E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21625 77f8b850ef06c79d252479f06c71a0c0 247 PANTHER PTHR24322 11 182 7.7E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS30260 447f7511f134432ca4460e2370f65193 68 Gene3D G3DSA:3.30.70.20 1 62 2.6E-14 T 23-04-2016 DC74_RS30260 447f7511f134432ca4460e2370f65193 68 PANTHER PTHR36923:SF1 1 62 4.4E-18 T 23-04-2016 DC74_RS30260 447f7511f134432ca4460e2370f65193 68 SUPERFAMILY SSF54862 2 61 4.08E-13 T 23-04-2016 DC74_RS30260 447f7511f134432ca4460e2370f65193 68 PANTHER PTHR36923 1 62 4.4E-18 T 23-04-2016 DC74_RS30260 447f7511f134432ca4460e2370f65193 68 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 2.7E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS30260 447f7511f134432ca4460e2370f65193 68 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 2.7E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS30260 447f7511f134432ca4460e2370f65193 68 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 2.7E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS30260 447f7511f134432ca4460e2370f65193 68 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 60 1.6E-11 T 23-04-2016 DC74_RS16515 3d611e1a3191a919c03563e466b5302a 294 PANTHER PTHR30177:SF4 10 292 1.9E-97 T 23-04-2016 DC74_RS16515 3d611e1a3191a919c03563e466b5302a 294 SUPERFAMILY SSF161098 91 277 7.33E-34 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16515 3d611e1a3191a919c03563e466b5302a 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 280 6.2E-18 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16515 3d611e1a3191a919c03563e466b5302a 294 Gene3D G3DSA:1.10.3720.10 57 277 4.3E-28 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16515 3d611e1a3191a919c03563e466b5302a 294 PANTHER PTHR30177 10 292 1.9E-97 T 23-04-2016 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 Pfam PF02803 Thiolase, C-terminal domain 275 397 3.1E-36 T 23-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 PIRSF PIRSF000429 3 400 7.9E-120 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 Gene3D G3DSA:3.40.47.10 192 278 9.7E-51 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 Gene3D G3DSA:3.40.47.10 7 131 9.7E-51 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 SUPERFAMILY SSF53901 7 273 9.09E-57 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 Gene3D G3DSA:3.40.47.10 152 191 4.6E-49 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 Gene3D G3DSA:3.40.47.10 280 398 4.6E-49 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 SUPERFAMILY SSF53901 277 397 2.65E-38 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 PANTHER PTHR18919 3 400 1.3E-158 T 23-04-2016 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 397 1.0E-127 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 PANTHER PTHR18919:SF69 3 400 1.3E-158 T 23-04-2016 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 23-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 DC74_RS29770 8bf30b93c128644086934cc217ef7ec7 406 Pfam PF00108 Thiolase, N-terminal domain 8 266 7.4E-55 T 23-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 DC74_RS00855 6d3a4d2eb965b375b2477029337de7c6 335 PANTHER PTHR10366:SF124 13 226 1.7E-20 T 23-04-2016 DC74_RS00855 6d3a4d2eb965b375b2477029337de7c6 335 Pfam PF01370 NAD dependent epimerase/dehydratase family 15 215 2.4E-10 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS00855 6d3a4d2eb965b375b2477029337de7c6 335 Gene3D G3DSA:3.40.50.720 13 252 5.1E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00855 6d3a4d2eb965b375b2477029337de7c6 335 SUPERFAMILY SSF51735 13 321 4.26E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00855 6d3a4d2eb965b375b2477029337de7c6 335 PANTHER PTHR10366 13 226 1.7E-20 T 23-04-2016 DC74_RS25820 0181f4e72c9d1dff5fce4dbb33445c85 327 PANTHER PTHR30465 43 327 3.0E-175 T 23-04-2016 DC74_RS25820 0181f4e72c9d1dff5fce4dbb33445c85 327 Gene3D G3DSA:1.10.3720.10 118 324 7.6E-23 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS25820 0181f4e72c9d1dff5fce4dbb33445c85 327 PANTHER PTHR30465:SF29 43 327 3.0E-175 T 23-04-2016 DC74_RS25820 0181f4e72c9d1dff5fce4dbb33445c85 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 143 327 6.3E-25 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS25820 0181f4e72c9d1dff5fce4dbb33445c85 327 SUPERFAMILY SSF161098 121 312 4.45E-21 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS25820 0181f4e72c9d1dff5fce4dbb33445c85 327 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 50 91 2.1E-11 T 23-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain DC74_RS08860 4c1cbb6477c4213ffc6a27d9a1975908 426 Gene3D G3DSA:3.30.9.10 168 318 1.6E-25 T 23-04-2016 DC74_RS08860 4c1cbb6477c4213ffc6a27d9a1975908 426 PANTHER PTHR10617:SF108 2 376 3.1E-93 T 23-04-2016 DC74_RS08860 4c1cbb6477c4213ffc6a27d9a1975908 426 PANTHER PTHR10617 2 376 3.1E-93 T 23-04-2016 DC74_RS08860 4c1cbb6477c4213ffc6a27d9a1975908 426 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 14 309 5.7E-78 T 23-04-2016 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 DC74_RS08860 4c1cbb6477c4213ffc6a27d9a1975908 426 SUPERFAMILY SSF51905 271 360 3.38E-40 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08860 4c1cbb6477c4213ffc6a27d9a1975908 426 SUPERFAMILY SSF51905 14 182 3.38E-40 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08860 4c1cbb6477c4213ffc6a27d9a1975908 426 Pfam PF00890 FAD binding domain 15 60 3.5E-7 T 23-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain DC74_RS08860 4c1cbb6477c4213ffc6a27d9a1975908 426 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 1.9E-12 T 23-04-2016 DC74_RS08860 4c1cbb6477c4213ffc6a27d9a1975908 426 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 15 37 1.9E-12 T 23-04-2016 DC74_RS08860 4c1cbb6477c4213ffc6a27d9a1975908 426 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 1.9E-12 T 23-04-2016 DC74_RS08860 4c1cbb6477c4213ffc6a27d9a1975908 426 Gene3D G3DSA:3.50.50.60 12 167 9.2E-23 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08860 4c1cbb6477c4213ffc6a27d9a1975908 426 Pfam PF01494 FAD binding domain 92 178 7.9E-6 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS08765 69d49df6f53e352724267a103011b83f 282 Pfam PF00455 DeoR C terminal sensor domain 83 252 1.2E-47 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain DC74_RS08765 69d49df6f53e352724267a103011b83f 282 SMART SM01134 80 254 2.3E-56 T 23-04-2016 DC74_RS08765 69d49df6f53e352724267a103011b83f 282 Gene3D G3DSA:3.40.50.1360 171 235 1.6E-14 T 23-04-2016 DC74_RS08765 69d49df6f53e352724267a103011b83f 282 Gene3D G3DSA:3.40.50.1360 84 137 1.6E-14 T 23-04-2016 DC74_RS08765 69d49df6f53e352724267a103011b83f 282 SMART SM00420 12 64 7.3E-18 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS08765 69d49df6f53e352724267a103011b83f 282 Gene3D G3DSA:1.10.10.10 11 61 1.6E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08765 69d49df6f53e352724267a103011b83f 282 PANTHER PTHR30363:SF13 6 275 4.9E-88 T 23-04-2016 DC74_RS08765 69d49df6f53e352724267a103011b83f 282 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 30 44 5.4E-10 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS08765 69d49df6f53e352724267a103011b83f 282 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 44 62 5.4E-10 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS08765 69d49df6f53e352724267a103011b83f 282 SUPERFAMILY SSF100950 85 139 1.0E-28 T 23-04-2016 DC74_RS08765 69d49df6f53e352724267a103011b83f 282 SUPERFAMILY SSF100950 173 254 1.0E-28 T 23-04-2016 DC74_RS08765 69d49df6f53e352724267a103011b83f 282 SUPERFAMILY SSF46785 10 67 2.42E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08765 69d49df6f53e352724267a103011b83f 282 PANTHER PTHR30363 6 275 4.9E-88 T 23-04-2016 DC74_RS08765 69d49df6f53e352724267a103011b83f 282 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 23-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 DC74_RS08765 69d49df6f53e352724267a103011b83f 282 Pfam PF08220 DeoR-like helix-turn-helix domain 12 63 1.8E-17 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS02355 28166cbc4138d187b79f53c5a5910544 139 PANTHER PTHR36849 1 101 7.5E-17 T 23-04-2016 DC74_RS02355 28166cbc4138d187b79f53c5a5910544 139 Pfam PF04343 Protein of unknown function, DUF488 1 94 1.5E-10 T 23-04-2016 IPR007438 Protein of unknown function DUF488 DC74_RS02355 28166cbc4138d187b79f53c5a5910544 139 PANTHER PTHR36849:SF1 1 101 7.5E-17 T 23-04-2016 DC74_RS39005 ef4383b097b5fcaf02e222aa7e7ef8ef 209 SUPERFAMILY SSF81342 16 207 4.79E-28 T 23-04-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 DC74_RS39005 ef4383b097b5fcaf02e222aa7e7ef8ef 209 Gene3D G3DSA:1.20.950.20 16 206 2.0E-43 T 23-04-2016 DC74_RS39005 ef4383b097b5fcaf02e222aa7e7ef8ef 209 Pfam PF01292 Prokaryotic cytochrome b561 19 182 1.5E-13 T 23-04-2016 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 DC74_RS17875 3fb5e63cd69e68f34805778342b285e3 277 PANTHER PTHR11904:SF1 3 261 7.4E-113 T 23-04-2016 DC74_RS17875 3fb5e63cd69e68f34805778342b285e3 277 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 50 90 - T 23-04-2016 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 DC74_RS17875 3fb5e63cd69e68f34805778342b285e3 277 Gene3D G3DSA:3.40.50.1580 3 268 2.4E-82 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS17875 3fb5e63cd69e68f34805778342b285e3 277 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 6 251 4.4E-87 T 23-04-2016 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 DC74_RS17875 3fb5e63cd69e68f34805778342b285e3 277 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 4 272 41.188 T 23-04-2016 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 DC74_RS17875 3fb5e63cd69e68f34805778342b285e3 277 Pfam PF01048 Phosphorylase superfamily 6 249 4.4E-38 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS17875 3fb5e63cd69e68f34805778342b285e3 277 PANTHER PTHR11904 3 261 7.4E-113 T 23-04-2016 IPR001369 PNP/MTAP phosphorylase DC74_RS17875 3fb5e63cd69e68f34805778342b285e3 277 SUPERFAMILY SSF53167 5 269 8.01E-81 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS05360 6e26205719a7a9ae7580ca44d849f485 374 PANTHER PTHR10909 1 370 4.6E-90 T 23-04-2016 DC74_RS05360 6e26205719a7a9ae7580ca44d849f485 374 PANTHER PTHR10909:SF229 1 370 4.6E-90 T 23-04-2016 DC74_RS05360 6e26205719a7a9ae7580ca44d849f485 374 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 4.9E-18 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS05360 6e26205719a7a9ae7580ca44d849f485 374 Gene3D G3DSA:2.40.110.10 121 216 1.1E-31 T 23-04-2016 DC74_RS05360 6e26205719a7a9ae7580ca44d849f485 374 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 367 7.2E-19 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS05360 6e26205719a7a9ae7580ca44d849f485 374 Gene3D G3DSA:1.20.140.10 217 372 8.6E-26 T 23-04-2016 DC74_RS05360 6e26205719a7a9ae7580ca44d849f485 374 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 214 1.0E-21 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS05360 6e26205719a7a9ae7580ca44d849f485 374 SUPERFAMILY SSF56645 1 236 4.06E-64 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS05360 6e26205719a7a9ae7580ca44d849f485 374 SUPERFAMILY SSF47203 226 370 4.99E-15 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS05360 6e26205719a7a9ae7580ca44d849f485 374 Gene3D G3DSA:1.10.540.10 1 117 8.7E-21 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS04985 467eb9a052befdfaca807497394049e4 117 TIGRFAM TIGR03889 nitrile_acc: nitrile hydratase accessory protein 22 94 1.0E-24 T 23-04-2016 IPR023808 Nitrile hydratase accessory protein, putative DC74_RS04985 467eb9a052befdfaca807497394049e4 117 SUPERFAMILY SSF50090 8 115 3.1E-21 T 23-04-2016 IPR008990 Electron transport accessory protein-like domain DC74_RS04985 467eb9a052befdfaca807497394049e4 117 Gene3D G3DSA:1.10.472.20 9 115 2.1E-19 T 23-04-2016 DC74_RS04985 467eb9a052befdfaca807497394049e4 117 Pfam PF02211 Nitrile hydratase beta subunit 17 110 1.0E-10 T 23-04-2016 IPR024690 Nitrile hydratase beta subunit domain GO:0018822 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 DC74_RS09560 c08a4d3a37f06004995669a63b0ed956 213 SMART SM00756 25 166 3.0E-53 T 23-04-2016 IPR012932 Vitamin K epoxide reductase DC74_RS09560 c08a4d3a37f06004995669a63b0ed956 213 PANTHER PTHR34573:SF2 29 213 4.5E-39 T 23-04-2016 DC74_RS09560 c08a4d3a37f06004995669a63b0ed956 213 PANTHER PTHR34573 29 213 4.5E-39 T 23-04-2016 DC74_RS09560 c08a4d3a37f06004995669a63b0ed956 213 Pfam PF07884 Vitamin K epoxide reductase family 31 162 1.6E-30 T 23-04-2016 IPR012932 Vitamin K epoxide reductase DC74_RS01955 aa782acee9f69d052686c9ab60c57e27 500 PANTHER PTHR23501:SF37 5 488 7.7E-138 T 23-04-2016 DC74_RS01955 aa782acee9f69d052686c9ab60c57e27 500 PANTHER PTHR23501 5 488 7.7E-138 T 23-04-2016 DC74_RS01955 aa782acee9f69d052686c9ab60c57e27 500 Gene3D G3DSA:1.20.1250.20 258 415 4.4E-17 T 23-04-2016 DC74_RS01955 aa782acee9f69d052686c9ab60c57e27 500 Gene3D G3DSA:1.20.1250.20 456 484 4.4E-17 T 23-04-2016 DC74_RS01955 aa782acee9f69d052686c9ab60c57e27 500 Pfam PF07690 Major Facilitator Superfamily 17 404 3.9E-47 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS01955 aa782acee9f69d052686c9ab60c57e27 500 SUPERFAMILY SSF103473 243 414 3.53E-59 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS01955 aa782acee9f69d052686c9ab60c57e27 500 SUPERFAMILY SSF103473 455 481 3.53E-59 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS01955 aa782acee9f69d052686c9ab60c57e27 500 SUPERFAMILY SSF103473 5 193 3.53E-59 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS01955 aa782acee9f69d052686c9ab60c57e27 500 Gene3D G3DSA:1.20.1250.20 7 191 1.0E-28 T 23-04-2016 DC74_RS10700 d057d44b2b78dce00599196cb3ae4cd1 383 SUPERFAMILY SSF56645 2 241 3.4E-86 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS10700 d057d44b2b78dce00599196cb3ae4cd1 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS10700 d057d44b2b78dce00599196cb3ae4cd1 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 1.8E-48 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS10700 d057d44b2b78dce00599196cb3ae4cd1 383 PANTHER PTHR10909 1 379 1.2E-177 T 23-04-2016 DC74_RS10700 d057d44b2b78dce00599196cb3ae4cd1 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 1.2E-28 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS10700 d057d44b2b78dce00599196cb3ae4cd1 383 Gene3D G3DSA:1.20.140.10 218 379 1.0E-65 T 23-04-2016 DC74_RS10700 d057d44b2b78dce00599196cb3ae4cd1 383 SUPERFAMILY SSF47203 228 379 1.13E-55 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS10700 d057d44b2b78dce00599196cb3ae4cd1 383 Gene3D G3DSA:2.40.110.10 121 217 5.3E-41 T 23-04-2016 DC74_RS10700 d057d44b2b78dce00599196cb3ae4cd1 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.2E-36 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS10700 d057d44b2b78dce00599196cb3ae4cd1 383 Gene3D G3DSA:1.10.540.10 1 117 3.4E-41 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS10700 d057d44b2b78dce00599196cb3ae4cd1 383 PIRSF PIRSF016578 3 380 1.1E-19 T 23-04-2016 DC74_RS10700 d057d44b2b78dce00599196cb3ae4cd1 383 PANTHER PTHR10909:SF186 1 379 1.2E-177 T 23-04-2016 DC74_RS13435 ca1648c3c7357e1db9558d2e04c2f44c 317 Gene3D G3DSA:3.40.50.150 51 173 1.6E-10 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS13435 ca1648c3c7357e1db9558d2e04c2f44c 317 PANTHER PTHR21320 45 317 2.4E-48 T 23-04-2016 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 DC74_RS13435 ca1648c3c7357e1db9558d2e04c2f44c 317 PANTHER PTHR21320:SF0 45 317 2.4E-48 T 23-04-2016 DC74_RS13435 ca1648c3c7357e1db9558d2e04c2f44c 317 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 48 316 3.8E-101 T 23-04-2016 IPR015324 Ribosomal protein Rsm22, bacterial-type GO:0006412|GO:0008168 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS13435 ca1648c3c7357e1db9558d2e04c2f44c 317 SUPERFAMILY SSF53335 45 207 7.97E-14 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS32065 fa75cbf9a25f1104159ce03b459cd161 121 SUPERFAMILY SSF48600 31 113 1.43E-24 T 23-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS32065 fa75cbf9a25f1104159ce03b459cd161 121 Gene3D G3DSA:1.20.59.10 16 105 8.4E-21 T 23-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS32065 fa75cbf9a25f1104159ce03b459cd161 121 TIGRFAM TIGR01795 CM_mono_cladeE: chorismate mutase 21 111 1.6E-44 T 23-04-2016 IPR010951 Chorismate mutase, bacteria DC74_RS32065 fa75cbf9a25f1104159ce03b459cd161 121 SMART SM00830 28 108 4.5E-23 T 23-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS32065 fa75cbf9a25f1104159ce03b459cd161 121 Pfam PF01817 Chorismate mutase type II 28 102 4.2E-18 T 23-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 SMART SM00387 725 835 1.7E-29 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 SUPERFAMILY SSF55874 672 831 1.7E-33 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 PANTHER PTHR24423 243 281 2.3E-106 T 23-04-2016 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 SUPERFAMILY SSF52402 243 345 4.49E-9 T 23-04-2016 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 14 222 2.8E-94 T 23-04-2016 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 PANTHER PTHR24423:SF562 243 281 2.3E-106 T 23-04-2016 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 PANTHER PTHR24423:SF562 12 189 2.3E-106 T 23-04-2016 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 Gene3D G3DSA:1.20.120.620 389 488 9.1E-16 T 23-04-2016 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 SUPERFAMILY SSF47384 606 683 2.35E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 Pfam PF13493 Domain of unknown function (DUF4118) 395 497 1.2E-20 T 23-04-2016 IPR025201 Sensor protein KdpD, transmembrane domain DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 Pfam PF00582 Universal stress protein family 242 345 2.8E-7 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 Gene3D G3DSA:1.10.287.130 609 669 2.4E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 PANTHER PTHR24423 595 831 2.3E-106 T 23-04-2016 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 PANTHER PTHR24423 12 189 2.3E-106 T 23-04-2016 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 SMART SM00388 615 683 4.3E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 Gene3D G3DSA:3.40.50.300 13 220 6.1E-95 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 PANTHER PTHR24423:SF562 595 831 2.3E-106 T 23-04-2016 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 795 813 1.3E-9 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 819 832 1.3E-9 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 762 776 1.3E-9 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 780 790 1.3E-9 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 Gene3D G3DSA:3.40.50.620 238 345 1.8E-10 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 Pfam PF00512 His Kinase A (phospho-acceptor) domain 616 683 9.4E-12 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 726 833 3.6E-18 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01830 3971a0babc3ddd8c3f95b414d391d539 845 Gene3D G3DSA:3.30.565.10 670 834 2.2E-33 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06610 fb005b74658ec5f09abe519d9947a1ce 313 Gene3D G3DSA:1.10.10.10 1 86 2.1E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06610 fb005b74658ec5f09abe519d9947a1ce 313 PANTHER PTHR30346 1 310 3.7E-74 T 23-04-2016 DC74_RS06610 fb005b74658ec5f09abe519d9947a1ce 313 Gene3D G3DSA:3.40.190.10 91 174 1.1E-15 T 23-04-2016 DC74_RS06610 fb005b74658ec5f09abe519d9947a1ce 313 Gene3D G3DSA:3.40.190.10 175 266 1.2E-21 T 23-04-2016 DC74_RS06610 fb005b74658ec5f09abe519d9947a1ce 313 SUPERFAMILY SSF46785 1 86 2.37E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06610 fb005b74658ec5f09abe519d9947a1ce 313 Pfam PF03466 LysR substrate binding domain 87 292 4.3E-27 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS06610 fb005b74658ec5f09abe519d9947a1ce 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.0E-23 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS06610 fb005b74658ec5f09abe519d9947a1ce 313 SUPERFAMILY SSF53850 91 296 1.15E-24 T 23-04-2016 DC74_RS06610 fb005b74658ec5f09abe519d9947a1ce 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS06610 fb005b74658ec5f09abe519d9947a1ce 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS06610 fb005b74658ec5f09abe519d9947a1ce 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS33475 a30728cbaeae840cd71d216bed457115 460 SUPERFAMILY SSF54368 13 116 1.7E-6 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS33475 a30728cbaeae840cd71d216bed457115 460 Pfam PF16952 Glutamine synthetase N-terminal domain 19 102 5.4E-9 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS33475 a30728cbaeae840cd71d216bed457115 460 PANTHER PTHR20852:SF16 1 459 6.0E-120 T 23-04-2016 DC74_RS33475 a30728cbaeae840cd71d216bed457115 460 Gene3D G3DSA:3.30.590.10 121 446 1.2E-85 T 23-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 DC74_RS33475 a30728cbaeae840cd71d216bed457115 460 SUPERFAMILY SSF55931 117 448 4.41E-81 T 23-04-2016 DC74_RS33475 a30728cbaeae840cd71d216bed457115 460 Gene3D G3DSA:3.10.20.70 12 119 5.2E-4 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS33475 a30728cbaeae840cd71d216bed457115 460 PANTHER PTHR20852 1 459 6.0E-120 T 23-04-2016 DC74_RS33475 a30728cbaeae840cd71d216bed457115 460 Pfam PF00120 Glutamine synthetase, catalytic domain 119 447 6.4E-76 T 23-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS33475 a30728cbaeae840cd71d216bed457115 460 SMART SM01230 117 370 5.0E-71 T 23-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS31160 59f61b68e564425da6cac8528895d998 199 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS31160 59f61b68e564425da6cac8528895d998 199 Gene3D G3DSA:3.10.20.30 2 77 1.1E-26 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS31160 59f61b68e564425da6cac8528895d998 199 SUPERFAMILY SSF54292 2 79 8.65E-21 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS31160 59f61b68e564425da6cac8528895d998 199 Pfam PF01799 [2Fe-2S] binding domain 116 183 5.7E-28 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS31160 59f61b68e564425da6cac8528895d998 199 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 53 3.5E-7 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS31160 59f61b68e564425da6cac8528895d998 199 PANTHER PTHR11908 2 80 2.3E-33 T 23-04-2016 DC74_RS31160 59f61b68e564425da6cac8528895d998 199 PANTHER PTHR11908 113 184 2.3E-33 T 23-04-2016 DC74_RS31160 59f61b68e564425da6cac8528895d998 199 Gene3D G3DSA:1.10.150.120 116 193 3.2E-33 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS31160 59f61b68e564425da6cac8528895d998 199 SUPERFAMILY SSF47741 121 191 1.2E-29 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS36720 382616fa103e7a0555d728affe7e19e2 447 SUPERFAMILY SSF53686 3 313 1.31E-60 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS36720 382616fa103e7a0555d728affe7e19e2 447 PANTHER PTHR10314 1 312 5.2E-48 T 23-04-2016 DC74_RS36720 382616fa103e7a0555d728affe7e19e2 447 Pfam PF00581 Rhodanese-like domain 349 438 7.3E-12 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS36720 382616fa103e7a0555d728affe7e19e2 447 SUPERFAMILY SSF52821 343 446 3.54E-24 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS36720 382616fa103e7a0555d728affe7e19e2 447 Gene3D G3DSA:3.40.250.10 337 446 6.7E-22 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS36720 382616fa103e7a0555d728affe7e19e2 447 Gene3D G3DSA:3.40.50.1100 156 314 9.7E-61 T 23-04-2016 DC74_RS36720 382616fa103e7a0555d728affe7e19e2 447 Gene3D G3DSA:3.40.50.1100 1 42 9.7E-61 T 23-04-2016 DC74_RS36720 382616fa103e7a0555d728affe7e19e2 447 SMART SM00450 345 443 1.5E-13 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS36720 382616fa103e7a0555d728affe7e19e2 447 PANTHER PTHR10314:SF100 1 312 5.2E-48 T 23-04-2016 DC74_RS36720 382616fa103e7a0555d728affe7e19e2 447 Gene3D G3DSA:3.40.50.1100 43 142 1.3E-13 T 23-04-2016 DC74_RS36720 382616fa103e7a0555d728affe7e19e2 447 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 6 281 4.7E-48 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS20605 c655f50d474bfa68466018a67a9ed186 84 Pfam PF06781 Uncharacterised protein family (UPF0233) 2 84 2.4E-27 T 23-04-2016 IPR009619 Cell division protein CrgA DC74_RS20605 c655f50d474bfa68466018a67a9ed186 84 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 84 21.88 T 23-04-2016 IPR009619 Cell division protein CrgA DC74_RS21400 5417c0a93a22b286c5d5fcd21822bcf5 631 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 420 621 1.3E-38 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS21400 5417c0a93a22b286c5d5fcd21822bcf5 631 SMART SM00331 393 622 8.3E-33 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS21400 5417c0a93a22b286c5d5fcd21822bcf5 631 SUPERFAMILY SSF81606 504 621 9.02E-8 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS21400 5417c0a93a22b286c5d5fcd21822bcf5 631 SUPERFAMILY SSF55874 141 200 6.57E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21400 5417c0a93a22b286c5d5fcd21822bcf5 631 SUPERFAMILY SSF55874 64 102 6.57E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21400 5417c0a93a22b286c5d5fcd21822bcf5 631 SUPERFAMILY SSF55781 243 371 2.13E-10 T 23-04-2016 IPR029016 GAF domain-like DC74_RS21400 5417c0a93a22b286c5d5fcd21822bcf5 631 PANTHER PTHR21021 317 631 3.3E-45 T 23-04-2016 DC74_RS21400 5417c0a93a22b286c5d5fcd21822bcf5 631 Gene3D G3DSA:3.30.450.40 225 370 1.3E-11 T 23-04-2016 IPR029016 GAF domain-like DC74_RS21400 5417c0a93a22b286c5d5fcd21822bcf5 631 Pfam PF13492 GAF domain 252 363 2.2E-6 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS21400 5417c0a93a22b286c5d5fcd21822bcf5 631 PANTHER PTHR21021:SF19 317 631 3.3E-45 T 23-04-2016 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 PIRSF PIRSF000144 6 760 0.0 T 23-04-2016 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 757 5.1E-290 T 23-04-2016 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 Gene3D G3DSA:3.40.228.10 194 396 7.1E-51 T 23-04-2016 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 SUPERFAMILY SSF53706 58 633 2.22E-144 T 23-04-2016 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 Pfam PF01568 Molydopterin dinucleotide binding domain 644 751 4.8E-9 T 23-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 PANTHER PTHR11615:SF114 1 263 2.7E-288 T 23-04-2016 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 PANTHER PTHR11615:SF114 281 756 2.7E-288 T 23-04-2016 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 Pfam PF00384 Molybdopterin oxidoreductase 120 518 2.9E-30 T 23-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 SUPERFAMILY SSF50692 637 758 5.65E-18 T 23-04-2016 IPR009010 Aspartate decarboxylase-like domain DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 Gene3D G3DSA:2.40.40.20 633 758 5.4E-11 T 23-04-2016 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 PANTHER PTHR11615 1 263 2.7E-288 T 23-04-2016 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 PANTHER PTHR11615 281 756 2.7E-288 T 23-04-2016 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 Gene3D G3DSA:3.40.50.740 120 193 2.7E-58 T 23-04-2016 DC74_RS12080 6e6ac0f3ddbefaddc2be9d7a979ab6fb 761 Gene3D G3DSA:3.40.50.740 397 630 2.7E-58 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 Gene3D G3DSA:3.40.50.1000 463 581 1.8E-36 T 23-04-2016 IPR023214 HAD-like domain DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 Pfam PF00702 haloacid dehalogenase-like hydrolase 313 548 1.9E-31 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 30 694 0.0 T 23-04-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 PANTHER PTHR24093:SF49 38 605 0.0 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 PANTHER PTHR24093:SF49 643 697 0.0 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 SUPERFAMILY SSF56784 313 583 3.66E-37 T 23-04-2016 IPR023214 HAD-like domain DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 29 698 40.608 T 23-04-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 SUPERFAMILY SSF81665 219 310 2.88E-11 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 SUPERFAMILY SSF81665 53 118 2.88E-11 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 SUPERFAMILY SSF81653 119 218 1.1E-21 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 318 324 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 Gene3D G3DSA:2.70.150.10 68 219 4.2E-25 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 Gene3D G3DSA:3.40.1110.10 327 462 3.7E-48 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 PANTHER PTHR24093 38 605 0.0 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 PANTHER PTHR24093 643 697 0.0 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 569 5.2E-25 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 553 5.2E-25 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 481 491 5.2E-25 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 316 330 5.2E-25 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 165 179 5.2E-25 T 23-04-2016 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 87 354 6.1E-33 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 387 619 6.6E-42 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS29190 99c0c514cbb68ca052a0c9dab203ad1f 701 Pfam PF00122 E1-E2 ATPase 87 307 2.9E-44 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 SUPERFAMILY SSF51735 153 328 2.8E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 Pfam PF00107 Zinc-binding dehydrogenase 192 314 1.1E-25 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 Gene3D G3DSA:3.40.50.720 186 301 4.4E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 SUPERFAMILY SSF50129 1 184 4.72E-49 T 23-04-2016 IPR011032 GroES-like DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 PANTHER PTHR11695:SF269 123 361 2.8E-100 T 23-04-2016 DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 PANTHER PTHR11695:SF269 14 107 2.8E-100 T 23-04-2016 DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 SUPERFAMILY SSF50129 317 359 1.29E-5 T 23-04-2016 IPR011032 GroES-like DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 149 1.7E-28 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 Gene3D G3DSA:3.90.180.10 1 185 1.2E-56 T 23-04-2016 IPR011032 GroES-like DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 PANTHER PTHR11695 123 361 2.8E-100 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 PANTHER PTHR11695 14 107 2.8E-100 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS13570 9e11a4f43675ef0f93454a1827fcc326 361 SMART SM00829 10 355 6.3E-7 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS16740 630ae4233b6080cac07b5805cee12bec 229 SUPERFAMILY SSF53335 56 216 5.38E-21 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS16740 630ae4233b6080cac07b5805cee12bec 229 Gene3D G3DSA:3.40.50.150 66 205 1.2E-16 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS16740 630ae4233b6080cac07b5805cee12bec 229 Pfam PF13649 Methyltransferase domain 74 161 1.2E-8 T 23-04-2016 DC74_RS36235 831b468a099e05061284e1f5e7afb73f 132 PANTHER PTHR30204 1 119 8.6E-25 T 23-04-2016 DC74_RS36235 831b468a099e05061284e1f5e7afb73f 132 SUPERFAMILY SSF46955 1 111 2.89E-28 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS36235 831b468a099e05061284e1f5e7afb73f 132 SMART SM00422 1 69 1.8E-25 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS36235 831b468a099e05061284e1f5e7afb73f 132 PANTHER PTHR30204:SF4 1 119 8.6E-25 T 23-04-2016 DC74_RS36235 831b468a099e05061284e1f5e7afb73f 132 Gene3D G3DSA:1.10.1660.10 1 115 1.9E-34 T 23-04-2016 DC74_RS36235 831b468a099e05061284e1f5e7afb73f 132 Pfam PF13411 MerR HTH family regulatory protein 1 64 1.1E-18 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS36235 831b468a099e05061284e1f5e7afb73f 132 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS36235 831b468a099e05061284e1f5e7afb73f 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 6.3E-11 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS36235 831b468a099e05061284e1f5e7afb73f 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 6.3E-11 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS36235 831b468a099e05061284e1f5e7afb73f 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 6.3E-11 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS12200 aff2faa9c344da3a33a84cf691089fdd 322 Gene3D G3DSA:1.25.40.10 71 200 7.7E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS12200 aff2faa9c344da3a33a84cf691089fdd 322 Gene3D G3DSA:1.25.40.10 247 296 7.7E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS12200 aff2faa9c344da3a33a84cf691089fdd 322 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 1 28 3.3E-4 T 23-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal DC74_RS15535 ff348f9b895e4215a43b389c9d96b7cd 337 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 121 134 - T 23-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 DC74_RS15535 ff348f9b895e4215a43b389c9d96b7cd 337 PANTHER PTHR18966:SF234 77 320 1.9E-82 T 23-04-2016 DC74_RS15535 ff348f9b895e4215a43b389c9d96b7cd 337 SUPERFAMILY SSF53850 79 322 3.26E-56 T 23-04-2016 DC74_RS15535 ff348f9b895e4215a43b389c9d96b7cd 337 Gene3D G3DSA:3.40.190.10 179 280 1.2E-21 T 23-04-2016 DC74_RS15535 ff348f9b895e4215a43b389c9d96b7cd 337 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 98 320 3.3E-49 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS15535 ff348f9b895e4215a43b389c9d96b7cd 337 Gene3D G3DSA:3.40.190.10 94 178 1.3E-32 T 23-04-2016 DC74_RS15535 ff348f9b895e4215a43b389c9d96b7cd 337 Gene3D G3DSA:3.40.190.10 281 323 1.3E-32 T 23-04-2016 DC74_RS15535 ff348f9b895e4215a43b389c9d96b7cd 337 PANTHER PTHR18966 77 320 1.9E-82 T 23-04-2016 DC74_RS15535 ff348f9b895e4215a43b389c9d96b7cd 337 SMART SM00062 97 323 1.6E-50 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS27360 e6ffc5c27fc4a256f394e46a55a07d59 433 PANTHER PTHR30582 73 432 5.3E-103 T 23-04-2016 DC74_RS27360 e6ffc5c27fc4a256f394e46a55a07d59 433 SUPERFAMILY SSF141523 276 402 4.19E-21 T 23-04-2016 DC74_RS27360 e6ffc5c27fc4a256f394e46a55a07d59 433 Pfam PF03734 L,D-transpeptidase catalytic domain 274 402 7.5E-10 T 23-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 DC74_RS27360 e6ffc5c27fc4a256f394e46a55a07d59 433 PANTHER PTHR30582:SF2 73 432 5.3E-103 T 23-04-2016 DC74_RS27360 e6ffc5c27fc4a256f394e46a55a07d59 433 Gene3D G3DSA:2.40.440.10 276 403 4.0E-18 T 23-04-2016 DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 Gene3D G3DSA:1.10.10.10 143 236 6.8E-36 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 SMART SM00448 20 139 1.5E-15 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 190 1.0E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 206 1.0E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 206 218 1.0E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 ProSitePatterns PS00622 LuxR-type HTH domain signature. 190 217 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 SUPERFAMILY SSF52172 20 157 3.7E-22 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 Pfam PF00196 Bacterial regulatory proteins, luxR family 175 230 9.4E-21 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 PANTHER PTHR26402:SF151 20 230 8.4E-55 T 23-04-2016 DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 Pfam PF00072 Response regulator receiver domain 22 139 2.3E-15 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 SMART SM00421 173 230 3.1E-25 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 PANTHER PTHR26402 20 230 8.4E-55 T 23-04-2016 DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 Gene3D G3DSA:3.40.50.2300 17 142 7.3E-24 T 23-04-2016 DC74_RS24340 43d3b84c40da927876a68d31c4f0e868 236 SUPERFAMILY SSF46894 166 235 2.96E-23 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS25840 613d72284d0ac68c3e1e0a6b29f955a4 355 PANTHER PTHR24220 23 344 2.7E-158 T 23-04-2016 DC74_RS25840 613d72284d0ac68c3e1e0a6b29f955a4 355 SMART SM00382 50 249 2.6E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS25840 613d72284d0ac68c3e1e0a6b29f955a4 355 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 250 336 6.3E-21 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS25840 613d72284d0ac68c3e1e0a6b29f955a4 355 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 312 1.3E-17 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS25840 613d72284d0ac68c3e1e0a6b29f955a4 355 PANTHER PTHR24220:SF535 23 344 2.7E-158 T 23-04-2016 DC74_RS25840 613d72284d0ac68c3e1e0a6b29f955a4 355 Pfam PF00005 ABC transporter 42 199 1.5E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS25840 613d72284d0ac68c3e1e0a6b29f955a4 355 SUPERFAMILY SSF52540 22 270 2.04E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25840 613d72284d0ac68c3e1e0a6b29f955a4 355 Gene3D G3DSA:3.40.50.300 21 273 7.6E-74 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25840 613d72284d0ac68c3e1e0a6b29f955a4 355 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 Gene3D G3DSA:3.20.20.10 54 298 4.9E-83 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 30 441 4.2E-128 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 PRINTS PR01181 Diaminopimelate decarboxylase signature 409 431 8.4E-25 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 PRINTS PR01181 Diaminopimelate decarboxylase signature 326 344 8.4E-25 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 PRINTS PR01181 Diaminopimelate decarboxylase signature 181 190 8.4E-25 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 PRINTS PR01181 Diaminopimelate decarboxylase signature 93 110 8.4E-25 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 SUPERFAMILY SSF51419 46 310 2.49E-72 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 75 93 - T 23-04-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 PANTHER PTHR11482:SF5 28 437 2.7E-143 T 23-04-2016 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 PANTHER PTHR11482 28 437 2.7E-143 T 23-04-2016 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 55 308 1.0E-54 T 23-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 Gene3D G3DSA:2.40.37.10 299 441 3.7E-45 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 35 442 38.57 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 95 107 2.2E-18 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 209 222 2.2E-18 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 399 412 2.2E-18 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 298 317 2.2E-18 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 75 93 2.2E-18 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 SUPERFAMILY SSF50621 288 441 3.56E-48 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS21130 e951dfdbb0f855f415195629553f4870 444 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 315 418 1.4E-14 T 23-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS03385 5f62750fe26d10f71860e1161ed2efe0 446 PANTHER PTHR31299 39 443 9.6E-71 T 23-04-2016 DC74_RS03385 5f62750fe26d10f71860e1161ed2efe0 446 SUPERFAMILY SSF159501 40 441 1.83E-96 T 23-04-2016 DC74_RS03385 5f62750fe26d10f71860e1161ed2efe0 446 Gene3D G3DSA:1.20.1440.30 181 306 8.0E-30 T 23-04-2016 DC74_RS03385 5f62750fe26d10f71860e1161ed2efe0 446 Gene3D G3DSA:3.30.1870.10 102 175 1.3E-19 T 23-04-2016 DC74_RS03385 5f62750fe26d10f71860e1161ed2efe0 446 Gene3D G3DSA:3.40.1660.10 39 101 1.5E-48 T 23-04-2016 DC74_RS03385 5f62750fe26d10f71860e1161ed2efe0 446 Gene3D G3DSA:3.40.1660.10 308 443 1.5E-48 T 23-04-2016 DC74_RS03385 5f62750fe26d10f71860e1161ed2efe0 446 PANTHER PTHR31299:SF0 39 443 9.6E-71 T 23-04-2016 DC74_RS03385 5f62750fe26d10f71860e1161ed2efe0 446 Pfam PF05139 Erythromycin esterase 100 440 7.6E-70 T 23-04-2016 IPR007815 Erythromycin esterase GO:0046677 DC74_RS03385 5f62750fe26d10f71860e1161ed2efe0 446 PIRSF PIRSF036794 22 446 2.7E-109 T 23-04-2016 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type DC74_RS11700 3905c34c72be37f6cbe7eb50e6c43154 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.0E-27 T 23-04-2016 IPR000390 Small multidrug resistance protein family GO:0016021 DC74_RS11700 3905c34c72be37f6cbe7eb50e6c43154 106 PANTHER PTHR30561 1 102 4.9E-42 T 23-04-2016 DC74_RS11700 3905c34c72be37f6cbe7eb50e6c43154 106 PANTHER PTHR30561:SF1 1 102 4.9E-42 T 23-04-2016 DC74_RS11700 3905c34c72be37f6cbe7eb50e6c43154 106 SUPERFAMILY SSF103481 5 104 4.05E-20 T 23-04-2016 DC74_RS07990 8d836649adea144b890ceb404f49fa0b 226 Pfam PF04299 Putative FMN-binding domain 8 165 3.4E-22 T 23-04-2016 IPR007396 Transcriptional regulator PAI 2-type DC74_RS07990 8d836649adea144b890ceb404f49fa0b 226 SUPERFAMILY SSF50475 10 182 4.15E-26 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS07990 8d836649adea144b890ceb404f49fa0b 226 Gene3D G3DSA:2.30.110.10 1 207 5.7E-34 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 PANTHER PTHR18919 1 406 7.5E-185 T 23-04-2016 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 23-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 5.7E-140 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 Gene3D G3DSA:3.40.47.10 170 209 3.1E-57 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 Gene3D G3DSA:3.40.47.10 289 404 3.1E-57 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 Pfam PF02803 Thiolase, C-terminal domain 282 404 5.4E-48 T 23-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 SUPERFAMILY SSF53901 3 282 9.52E-69 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 Gene3D G3DSA:3.40.47.10 210 288 4.1E-61 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 Gene3D G3DSA:3.40.47.10 4 125 4.1E-61 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 PANTHER PTHR18919:SF69 1 406 7.5E-185 T 23-04-2016 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 PIRSF PIRSF000429 1 406 4.4E-130 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 SUPERFAMILY SSF53901 283 404 7.57E-44 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS17285 0dff1dc26ffb306687648d4c7598b848 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 4.8E-61 T 23-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 DC74_RS10295 916bb314b596a3aa127656f85e5fa4d0 453 Hamap MF_02111 Pup--protein ligase [pafA]. 1 453 49.846 T 23-04-2016 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 UniPathway: UPA00997|UniPathway: UPA00998 DC74_RS10295 916bb314b596a3aa127656f85e5fa4d0 453 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 453 1.2E-229 T 23-04-2016 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 UniPathway: UPA00997|UniPathway: UPA00998 DC74_RS10295 916bb314b596a3aa127656f85e5fa4d0 453 PIRSF PIRSF018077 1 453 3.5E-180 T 23-04-2016 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 UniPathway: UPA00997|UniPathway: UPA00998 DC74_RS10295 916bb314b596a3aa127656f85e5fa4d0 453 PANTHER PTHR42307:SF1 1 453 0.0 T 23-04-2016 DC74_RS10295 916bb314b596a3aa127656f85e5fa4d0 453 PANTHER PTHR42307 1 453 0.0 T 23-04-2016 DC74_RS10295 916bb314b596a3aa127656f85e5fa4d0 453 Pfam PF03136 Pup-ligase protein 4 423 2.5E-156 T 23-04-2016 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 UniPathway: UPA00997|UniPathway: UPA00998 DC74_RS25100 3743546e7bf4594930c07eb764de3e19 192 SUPERFAMILY SSF52317 1 180 7.98E-49 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS25100 3743546e7bf4594930c07eb764de3e19 192 Pfam PF01965 DJ-1/PfpI family 3 177 1.6E-44 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS25100 3743546e7bf4594930c07eb764de3e19 192 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 3 180 4.6E-46 T 23-04-2016 IPR006286 Peptidase C56, PfpI GO:0016798 DC74_RS25100 3743546e7bf4594930c07eb764de3e19 192 Gene3D G3DSA:3.40.50.880 1 185 7.5E-49 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS25100 3743546e7bf4594930c07eb764de3e19 192 PANTHER PTHR11019:SF135 3 181 1.2E-24 T 23-04-2016 DC74_RS25100 3743546e7bf4594930c07eb764de3e19 192 PANTHER PTHR11019 3 181 1.2E-24 T 23-04-2016 DC74_RS16670 d1adf4a74833bd725a7956c031ba34d4 166 Pfam PF01668 SmpB protein 17 79 3.7E-30 T 23-04-2016 IPR000037 SsrA-binding protein GO:0003723 DC74_RS16670 d1adf4a74833bd725a7956c031ba34d4 166 Hamap MF_00023 SsrA-binding protein [smpB]. 1 166 70.304 T 23-04-2016 IPR000037 SsrA-binding protein GO:0003723 DC74_RS16670 d1adf4a74833bd725a7956c031ba34d4 166 SUPERFAMILY SSF74982 10 140 6.54E-52 T 23-04-2016 IPR023620 Small protein B DC74_RS16670 d1adf4a74833bd725a7956c031ba34d4 166 PANTHER PTHR30308:SF2 5 163 2.7E-78 T 23-04-2016 DC74_RS16670 d1adf4a74833bd725a7956c031ba34d4 166 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 17 140 5.0E-60 T 23-04-2016 IPR000037 SsrA-binding protein GO:0003723 DC74_RS16670 d1adf4a74833bd725a7956c031ba34d4 166 PANTHER PTHR30308 5 163 2.7E-78 T 23-04-2016 DC74_RS16670 d1adf4a74833bd725a7956c031ba34d4 166 Gene3D G3DSA:2.40.280.10 15 135 3.4E-52 T 23-04-2016 IPR023620 Small protein B DC74_RS16670 d1adf4a74833bd725a7956c031ba34d4 166 ProSitePatterns PS01317 SsrA-binding protein. 35 47 - T 23-04-2016 IPR020081 SsrA-binding protein, conserved site DC74_RS16670 d1adf4a74833bd725a7956c031ba34d4 166 TIGRFAM TIGR00086 smpB: SsrA-binding protein 17 157 8.3E-57 T 23-04-2016 IPR000037 SsrA-binding protein GO:0003723 DC74_RS21840 d6e40f65c7919778826ad8d35ffd4f2b 312 SUPERFAMILY SSF88946 18 107 5.1E-14 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21840 d6e40f65c7919778826ad8d35ffd4f2b 312 PANTHER PTHR30173:SF25 1 312 3.5E-132 T 23-04-2016 DC74_RS21840 d6e40f65c7919778826ad8d35ffd4f2b 312 Pfam PF04542 Sigma-70 region 2 29 93 5.8E-14 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21840 d6e40f65c7919778826ad8d35ffd4f2b 312 Pfam PF08281 Sigma-70, region 4 125 176 5.8E-12 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21840 d6e40f65c7919778826ad8d35ffd4f2b 312 PANTHER PTHR30173 1 312 3.5E-132 T 23-04-2016 DC74_RS21840 d6e40f65c7919778826ad8d35ffd4f2b 312 Gene3D G3DSA:1.10.10.10 125 179 8.9E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21840 d6e40f65c7919778826ad8d35ffd4f2b 312 Gene3D G3DSA:1.10.1740.10 18 101 4.0E-13 T 23-04-2016 DC74_RS21840 d6e40f65c7919778826ad8d35ffd4f2b 312 Gene3D G3DSA:3.10.450.50 187 301 5.6E-11 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS21840 d6e40f65c7919778826ad8d35ffd4f2b 312 SUPERFAMILY SSF54427 189 304 4.96E-16 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS21840 d6e40f65c7919778826ad8d35ffd4f2b 312 SUPERFAMILY SSF88659 94 179 9.91E-11 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21840 d6e40f65c7919778826ad8d35ffd4f2b 312 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 27 304 1.2E-105 T 23-04-2016 IPR014303 RNA polymerase sigma-70, ECF type DC74_RS21840 d6e40f65c7919778826ad8d35ffd4f2b 312 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 177 2.2E-18 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21930 9045424021d901241e00fc98a0f2e2ff 110 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 1 97 19.274 T 23-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family DC74_RS21930 9045424021d901241e00fc98a0f2e2ff 110 Pfam PF02575 YbaB/EbfC DNA-binding family 6 97 1.2E-27 T 23-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family DC74_RS21930 9045424021d901241e00fc98a0f2e2ff 110 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 90 4.6E-18 T 23-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family DC74_RS21930 9045424021d901241e00fc98a0f2e2ff 110 Gene3D G3DSA:3.30.1310.10 1 103 6.8E-34 T 23-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family DC74_RS21930 9045424021d901241e00fc98a0f2e2ff 110 PANTHER PTHR33449:SF1 1 109 1.4E-29 T 23-04-2016 DC74_RS21930 9045424021d901241e00fc98a0f2e2ff 110 PANTHER PTHR33449 1 109 1.4E-29 T 23-04-2016 DC74_RS21930 9045424021d901241e00fc98a0f2e2ff 110 SUPERFAMILY SSF82607 1 95 4.05E-24 T 23-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family DC74_RS21930 9045424021d901241e00fc98a0f2e2ff 110 PIRSF PIRSF004555 1 110 1.1E-28 T 23-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family DC74_RS21175 fee7f45c08f63c301263fe25e71218bb 308 PANTHER PTHR21022:SF0 1 296 9.9E-90 T 23-04-2016 DC74_RS21175 fee7f45c08f63c301263fe25e71218bb 308 PANTHER PTHR21022 1 296 9.9E-90 T 23-04-2016 DC74_RS21175 fee7f45c08f63c301263fe25e71218bb 308 SUPERFAMILY SSF53850 5 190 5.3E-48 T 23-04-2016 DC74_RS21175 fee7f45c08f63c301263fe25e71218bb 308 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 159 181 - T 23-04-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 DC74_RS21175 fee7f45c08f63c301263fe25e71218bb 308 Gene3D G3DSA:3.40.190.10 94 171 3.2E-18 T 23-04-2016 DC74_RS21175 fee7f45c08f63c301263fe25e71218bb 308 Pfam PF00800 Prephenate dehydratase 8 184 2.5E-44 T 23-04-2016 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 DC74_RS21175 fee7f45c08f63c301263fe25e71218bb 308 PIRSF PIRSF001500 2 279 1.4E-57 T 23-04-2016 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 DC74_RS21175 fee7f45c08f63c301263fe25e71218bb 308 Gene3D G3DSA:3.30.70.260 190 277 6.3E-29 T 23-04-2016 DC74_RS21175 fee7f45c08f63c301263fe25e71218bb 308 Gene3D G3DSA:3.40.190.10 5 93 3.2E-25 T 23-04-2016 DC74_RS21175 fee7f45c08f63c301263fe25e71218bb 308 SUPERFAMILY SSF55021 178 276 2.81E-23 T 23-04-2016 DC74_RS27585 67b5ddfa74252168f3a30eb2bb7b9402 702 Gene3D G3DSA:3.30.70.270 253 414 1.8E-51 T 23-04-2016 DC74_RS27585 67b5ddfa74252168f3a30eb2bb7b9402 702 PANTHER PTHR33121:SF13 386 696 1.3E-80 T 23-04-2016 DC74_RS27585 67b5ddfa74252168f3a30eb2bb7b9402 702 Pfam PF00563 EAL domain 428 658 7.0E-72 T 23-04-2016 IPR001633 EAL domain DC74_RS27585 67b5ddfa74252168f3a30eb2bb7b9402 702 Gene3D G3DSA:3.20.20.450 427 672 2.3E-92 T 23-04-2016 IPR001633 EAL domain DC74_RS27585 67b5ddfa74252168f3a30eb2bb7b9402 702 SMART SM00052 421 665 4.9E-103 T 23-04-2016 IPR001633 EAL domain DC74_RS27585 67b5ddfa74252168f3a30eb2bb7b9402 702 SUPERFAMILY SSF55073 256 406 5.34E-45 T 23-04-2016 IPR029787 Nucleotide cyclase DC74_RS27585 67b5ddfa74252168f3a30eb2bb7b9402 702 Pfam PF00990 Diguanylate cyclase, GGDEF domain 253 405 4.7E-42 T 23-04-2016 IPR000160 GGDEF domain DC74_RS27585 67b5ddfa74252168f3a30eb2bb7b9402 702 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 251 405 1.7E-35 T 23-04-2016 IPR000160 GGDEF domain DC74_RS27585 67b5ddfa74252168f3a30eb2bb7b9402 702 PANTHER PTHR33121 386 696 1.3E-80 T 23-04-2016 DC74_RS27585 67b5ddfa74252168f3a30eb2bb7b9402 702 SUPERFAMILY SSF141868 427 673 1.24E-83 T 23-04-2016 IPR001633 EAL domain DC74_RS27585 67b5ddfa74252168f3a30eb2bb7b9402 702 SMART SM00267 245 411 1.4E-50 T 23-04-2016 IPR000160 GGDEF domain DC74_RS08290 f3bc34ec9c3a18d1489fb1a8b32f1837 247 PANTHER PTHR11751 31 119 3.5E-26 T 23-04-2016 DC74_RS08290 f3bc34ec9c3a18d1489fb1a8b32f1837 247 SUPERFAMILY SSF46785 27 97 1.49E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08290 f3bc34ec9c3a18d1489fb1a8b32f1837 247 SMART SM00895 103 231 4.0E-17 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS08290 f3bc34ec9c3a18d1489fb1a8b32f1837 247 Gene3D G3DSA:1.20.120.530 97 242 1.3E-36 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS08290 f3bc34ec9c3a18d1489fb1a8b32f1837 247 SUPERFAMILY SSF48008 98 238 4.71E-27 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS08290 f3bc34ec9c3a18d1489fb1a8b32f1837 247 SMART SM00345 35 93 2.9E-12 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS08290 f3bc34ec9c3a18d1489fb1a8b32f1837 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 93 1.9E-15 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS08290 f3bc34ec9c3a18d1489fb1a8b32f1837 247 PANTHER PTHR11751:SF3 31 119 3.5E-26 T 23-04-2016 DC74_RS08290 f3bc34ec9c3a18d1489fb1a8b32f1837 247 Pfam PF07729 FCD domain 103 230 4.1E-17 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS08290 f3bc34ec9c3a18d1489fb1a8b32f1837 247 Gene3D G3DSA:1.10.10.10 30 94 1.2E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07080 befe773dddbc78f2f51cd8e3dadbee61 299 PANTHER PTHR10992 28 296 8.7E-33 T 23-04-2016 DC74_RS07080 befe773dddbc78f2f51cd8e3dadbee61 299 Gene3D G3DSA:3.40.50.1820 23 294 2.1E-44 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS07080 befe773dddbc78f2f51cd8e3dadbee61 299 PANTHER PTHR10992:SF771 28 296 8.7E-33 T 23-04-2016 DC74_RS07080 befe773dddbc78f2f51cd8e3dadbee61 299 SUPERFAMILY SSF53474 25 294 2.41E-42 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS07080 befe773dddbc78f2f51cd8e3dadbee61 299 Pfam PF12697 Alpha/beta hydrolase family 51 287 4.6E-16 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS35010 85cbc179549a2c019ecaba82b4caad27 150 SUPERFAMILY SSF46785 4 149 5.69E-40 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35010 85cbc179549a2c019ecaba82b4caad27 150 PANTHER PTHR33164:SF5 9 149 4.0E-55 T 23-04-2016 DC74_RS35010 85cbc179549a2c019ecaba82b4caad27 150 Pfam PF01047 MarR family 42 100 2.7E-17 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS35010 85cbc179549a2c019ecaba82b4caad27 150 SMART SM00347 35 133 7.0E-27 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS35010 85cbc179549a2c019ecaba82b4caad27 150 PANTHER PTHR33164 9 149 4.0E-55 T 23-04-2016 DC74_RS35010 85cbc179549a2c019ecaba82b4caad27 150 Gene3D G3DSA:1.10.10.10 3 148 3.4E-46 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19065 277bb9228ab2392ed307be53ad0fbd47 251 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 108 230 1.6E-43 T 23-04-2016 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 DC74_RS19065 277bb9228ab2392ed307be53ad0fbd47 251 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 159 214 4.0E-25 T 23-04-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 DC74_RS19065 277bb9228ab2392ed307be53ad0fbd47 251 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 110 231 9.8E-40 T 23-04-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 DC74_RS19065 277bb9228ab2392ed307be53ad0fbd47 251 PANTHER PTHR10884 30 232 1.5E-83 T 23-04-2016 DC74_RS19065 277bb9228ab2392ed307be53ad0fbd47 251 PANTHER PTHR10884:SF6 30 232 1.5E-83 T 23-04-2016 DC74_RS19065 277bb9228ab2392ed307be53ad0fbd47 251 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 82 239 28.008 T 23-04-2016 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 DC74_RS19065 277bb9228ab2392ed307be53ad0fbd47 251 SUPERFAMILY SSF143243 93 247 1.31E-45 T 23-04-2016 DC74_RS09380 71373cc20b5a75271ba9ad3167dbaafa 312 Pfam PF00551 Formyl transferase 2 179 1.4E-33 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS09380 71373cc20b5a75271ba9ad3167dbaafa 312 Pfam PF02911 Formyl transferase, C-terminal domain 204 302 5.4E-24 T 23-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS09380 71373cc20b5a75271ba9ad3167dbaafa 312 SUPERFAMILY SSF53328 1 205 1.57E-57 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS09380 71373cc20b5a75271ba9ad3167dbaafa 312 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 305 33.229 T 23-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS09380 71373cc20b5a75271ba9ad3167dbaafa 312 SUPERFAMILY SSF50486 207 310 2.98E-27 T 23-04-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 DC74_RS09380 71373cc20b5a75271ba9ad3167dbaafa 312 Gene3D G3DSA:3.40.50.170 1 205 5.8E-61 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS09380 71373cc20b5a75271ba9ad3167dbaafa 312 PANTHER PTHR11138 1 312 6.4E-104 T 23-04-2016 DC74_RS09380 71373cc20b5a75271ba9ad3167dbaafa 312 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 303 2.5E-69 T 23-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS09380 71373cc20b5a75271ba9ad3167dbaafa 312 Gene3D G3DSA:3.10.25.10 208 311 8.2E-31 T 23-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS24835 60e750368e0daa2a6a28bfaf9ee9cbed 236 SUPERFAMILY SSF46785 8 77 6.62E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24835 60e750368e0daa2a6a28bfaf9ee9cbed 236 SMART SM00895 102 226 5.9E-16 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS24835 60e750368e0daa2a6a28bfaf9ee9cbed 236 SUPERFAMILY SSF48008 99 229 3.92E-20 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS24835 60e750368e0daa2a6a28bfaf9ee9cbed 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 73 1.9E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS24835 60e750368e0daa2a6a28bfaf9ee9cbed 236 Pfam PF07729 FCD domain 103 222 3.4E-19 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS24835 60e750368e0daa2a6a28bfaf9ee9cbed 236 Gene3D G3DSA:1.10.10.10 5 75 6.1E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24835 60e750368e0daa2a6a28bfaf9ee9cbed 236 Gene3D G3DSA:1.20.120.530 90 224 3.5E-19 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS24835 60e750368e0daa2a6a28bfaf9ee9cbed 236 SMART SM00345 15 73 4.8E-9 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS24835 60e750368e0daa2a6a28bfaf9ee9cbed 236 PANTHER PTHR11751 14 80 2.5E-17 T 23-04-2016 DC74_RS24835 60e750368e0daa2a6a28bfaf9ee9cbed 236 PANTHER PTHR11751 100 118 2.5E-17 T 23-04-2016 DC74_RS21030 fa80f111785805c863e73395871166bc 293 SUPERFAMILY SSF56784 11 290 1.02E-55 T 23-04-2016 IPR023214 HAD-like domain DC74_RS21030 fa80f111785805c863e73395871166bc 293 Pfam PF08282 haloacid dehalogenase-like hydrolase 15 286 2.0E-47 T 23-04-2016 IPR023214 HAD-like domain DC74_RS21030 fa80f111785805c863e73395871166bc 293 PANTHER PTHR10000 13 292 2.1E-60 T 23-04-2016 DC74_RS21030 fa80f111785805c863e73395871166bc 293 Gene3D G3DSA:3.40.50.1000 10 82 2.2E-45 T 23-04-2016 IPR023214 HAD-like domain DC74_RS21030 fa80f111785805c863e73395871166bc 293 Gene3D G3DSA:3.40.50.1000 194 291 2.2E-45 T 23-04-2016 IPR023214 HAD-like domain DC74_RS21030 fa80f111785805c863e73395871166bc 293 PANTHER PTHR10000:SF8 13 292 2.1E-60 T 23-04-2016 DC74_RS38950 10e3d90b3c6d14b273e605d819e22862 163 Pfam PF04982 HPP family 43 160 1.0E-22 T 23-04-2016 IPR007065 HPP DC74_RS15380 a4a3fd3c1ed89785a965c64bed2f61a9 487 Pfam PF00324 Amino acid permease 37 455 1.6E-116 T 23-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 DC74_RS15380 a4a3fd3c1ed89785a965c64bed2f61a9 487 ProSitePatterns PS00218 Amino acid permeases signature. 62 92 - T 23-04-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 DC74_RS15380 a4a3fd3c1ed89785a965c64bed2f61a9 487 PANTHER PTHR11785 23 471 4.9E-226 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS15380 a4a3fd3c1ed89785a965c64bed2f61a9 487 PIRSF PIRSF006060 13 486 4.8E-73 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS15380 a4a3fd3c1ed89785a965c64bed2f61a9 487 PANTHER PTHR11785:SF24 23 471 4.9E-226 T 23-04-2016 DC74_RS35750 45b69a6e7ceace511206ed4585296f1f 442 PANTHER PTHR10859 26 349 7.5E-12 T 23-04-2016 DC74_RS35750 45b69a6e7ceace511206ed4585296f1f 442 Pfam PF13641 Glycosyltransferase like family 2 47 298 1.2E-24 T 23-04-2016 DC74_RS35750 45b69a6e7ceace511206ed4585296f1f 442 Gene3D G3DSA:3.90.550.10 49 306 8.2E-17 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS35750 45b69a6e7ceace511206ed4585296f1f 442 SUPERFAMILY SSF53448 48 317 9.0E-28 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SUPERFAMILY SSF51735 1186 1388 2.94E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SUPERFAMILY SSF47336 1790 1863 5.5E-19 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 PANTHER PTHR11712 612 947 2.3E-300 T 23-04-2016 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 PANTHER PTHR11712 1449 1681 2.3E-300 T 23-04-2016 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 PANTHER PTHR11712 7 590 2.3E-300 T 23-04-2016 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 380 2.3E-40 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SUPERFAMILY SSF51735 936 1172 2.83E-20 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SUPERFAMILY SSF53901 150 376 4.1E-81 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SUPERFAMILY SSF53901 6 121 4.1E-81 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SUPERFAMILY SSF53901 408 429 4.1E-81 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SMART SM00826 1407 1572 2.1E-16 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Gene3D G3DSA:3.40.47.10 267 433 2.0E-59 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Gene3D G3DSA:3.40.47.10 7 266 8.8E-76 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Pfam PF08659 KR domain 1187 1384 3.2E-51 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 531 852 8.0E-98 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Pfam PF00550 Phosphopantetheine attachment site 1799 1862 5.6E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Gene3D G3DSA:3.40.366.10 522 677 2.9E-71 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Gene3D G3DSA:3.40.366.10 740 840 2.9E-71 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SUPERFAMILY SSF55048 681 739 8.37E-9 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 167 183 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Gene3D G3DSA:3.40.50.720 1186 1415 1.5E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 383 494 2.5E-20 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Gene3D G3DSA:1.10.1200.10 1787 1865 2.5E-25 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SUPERFAMILY SSF52151 742 839 4.45E-62 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SUPERFAMILY SSF52151 528 581 4.45E-62 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SUPERFAMILY SSF52151 610 683 4.45E-62 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SMART SM00823 Phosphopantetheine attachment site 1798 1867 0.0056 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1822 1837 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Pfam PF14765 Polyketide synthase dehydratase 1407 1684 8.8E-46 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1187 1385 1.1E-61 T 23-04-2016 DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Pfam PF00698 Acyl transferase domain 530 822 2.8E-42 T 23-04-2016 IPR014043 Acyl transferase DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 SMART SM00825 Beta-ketoacyl synthase 7 433 2.5E-179 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS39285 9b84bd95ef8bc962d2b9b6a98f9e1a25 1873 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 254 1.8E-69 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS02730 a7d05b93ef7674e43c58639d9672709d 216 SMART SM01120 30 206 1.7E-63 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 DC74_RS02730 a7d05b93ef7674e43c58639d9672709d 216 PANTHER PTHR28629 1 210 7.2E-63 T 23-04-2016 DC74_RS02730 a7d05b93ef7674e43c58639d9672709d 216 Pfam PF02734 DAK2 domain 30 205 4.3E-49 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 DC74_RS02730 a7d05b93ef7674e43c58639d9672709d 216 SUPERFAMILY SSF101473 2 207 5.49E-49 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 DC74_RS02730 a7d05b93ef7674e43c58639d9672709d 216 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 7 205 1.9E-60 T 23-04-2016 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00563+2.7.-.- DC74_RS13105 15406afd7f8bcb6ca43b928b2b50f5b0 271 SUPERFAMILY SSF55681 25 143 2.65E-58 T 23-04-2016 DC74_RS13105 15406afd7f8bcb6ca43b928b2b50f5b0 271 SUPERFAMILY SSF55681 189 262 2.65E-58 T 23-04-2016 DC74_RS13105 15406afd7f8bcb6ca43b928b2b50f5b0 271 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 84 99 - T 23-04-2016 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 DC74_RS13105 15406afd7f8bcb6ca43b928b2b50f5b0 271 Hamap MF_00013 Octanoyltransferase [lipB]. 14 264 31.825 T 23-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 DC74_RS13105 15406afd7f8bcb6ca43b928b2b50f5b0 271 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 88 140 1.0E-21 T 23-04-2016 DC74_RS13105 15406afd7f8bcb6ca43b928b2b50f5b0 271 PIRSF PIRSF016262 13 266 3.8E-57 T 23-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 DC74_RS13105 15406afd7f8bcb6ca43b928b2b50f5b0 271 Gene3D G3DSA:3.90.1550.10 25 147 1.5E-73 T 23-04-2016 DC74_RS13105 15406afd7f8bcb6ca43b928b2b50f5b0 271 Gene3D G3DSA:3.90.1550.10 190 261 1.5E-73 T 23-04-2016 DC74_RS13105 15406afd7f8bcb6ca43b928b2b50f5b0 271 PANTHER PTHR10993 15 145 3.3E-67 T 23-04-2016 DC74_RS13105 15406afd7f8bcb6ca43b928b2b50f5b0 271 PANTHER PTHR10993 188 267 3.3E-67 T 23-04-2016 DC74_RS27410 b3467751b88e21c1e35da7e2685cf690 434 SUPERFAMILY SSF53756 223 403 6.8E-48 T 23-04-2016 DC74_RS27410 b3467751b88e21c1e35da7e2685cf690 434 SUPERFAMILY SSF53756 73 196 6.8E-48 T 23-04-2016 DC74_RS27410 b3467751b88e21c1e35da7e2685cf690 434 SUPERFAMILY SSF53756 2 45 6.8E-48 T 23-04-2016 DC74_RS27410 b3467751b88e21c1e35da7e2685cf690 434 PANTHER PTHR12526 88 206 4.9E-31 T 23-04-2016 DC74_RS27410 b3467751b88e21c1e35da7e2685cf690 434 PANTHER PTHR12526 228 415 4.9E-31 T 23-04-2016 DC74_RS27410 b3467751b88e21c1e35da7e2685cf690 434 PANTHER PTHR12526 1 60 4.9E-31 T 23-04-2016 DC74_RS27410 b3467751b88e21c1e35da7e2685cf690 434 PANTHER PTHR12526:SF374 88 206 4.9E-31 T 23-04-2016 DC74_RS27410 b3467751b88e21c1e35da7e2685cf690 434 PANTHER PTHR12526:SF374 228 415 4.9E-31 T 23-04-2016 DC74_RS27410 b3467751b88e21c1e35da7e2685cf690 434 PANTHER PTHR12526:SF374 1 60 4.9E-31 T 23-04-2016 DC74_RS27410 b3467751b88e21c1e35da7e2685cf690 434 Pfam PF00534 Glycosyl transferases group 1 226 381 3.9E-24 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 DC74_RS27410 b3467751b88e21c1e35da7e2685cf690 434 Gene3D G3DSA:3.40.50.2000 226 382 8.3E-14 T 23-04-2016 DC74_RS03440 529246480368d2ae00a1776daecef028 141 Pfam PF12680 SnoaL-like domain 13 119 1.0E-12 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS03440 529246480368d2ae00a1776daecef028 141 SUPERFAMILY SSF54427 7 129 3.25E-33 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS03440 529246480368d2ae00a1776daecef028 141 Gene3D G3DSA:3.10.450.50 3 130 1.5E-50 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS36645 453e1f2284be7451112218bec5c8dec0 114 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 50 1.7E-17 T 23-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 DC74_RS36645 453e1f2284be7451112218bec5c8dec0 114 Pfam PF02416 mttA/Hcf106 family 8 53 6.6E-18 T 23-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 DC74_RS36645 453e1f2284be7451112218bec5c8dec0 114 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 3 75 18.098 T 23-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 DC74_RS15215 dd3514d6f0b77fd0efae8deae73c07bc 106 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 21.896 T 23-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15215 dd3514d6f0b77fd0efae8deae73c07bc 106 PANTHER PTHR21349 1 101 2.0E-32 T 23-04-2016 DC74_RS15215 dd3514d6f0b77fd0efae8deae73c07bc 106 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 23-04-2016 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15215 dd3514d6f0b77fd0efae8deae73c07bc 106 Pfam PF00829 Ribosomal prokaryotic L21 protein 2 101 1.1E-30 T 23-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 DC74_RS15215 dd3514d6f0b77fd0efae8deae73c07bc 106 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 9.2E-23 T 23-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15215 dd3514d6f0b77fd0efae8deae73c07bc 106 SUPERFAMILY SSF141091 1 101 4.84E-30 T 23-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 SUPERFAMILY SSF52518 13 277 3.06E-71 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 Gene3D G3DSA:3.40.50.920 492 621 2.1E-31 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 PANTHER PTHR11624:SF2 14 622 2.5E-245 T 23-04-2016 DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 Gene3D G3DSA:3.40.50.970 314 491 1.2E-52 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 Pfam PF02780 Transketolase, C-terminal domain 494 613 3.7E-29 T 23-04-2016 IPR033248 Transketolase, C-terminal domain DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 Gene3D G3DSA:3.40.50.970 17 281 1.9E-74 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 PANTHER PTHR11624 14 622 2.5E-245 T 23-04-2016 IPR033247 Transketolase family DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 Pfam PF02779 Transketolase, pyrimidine binding domain 317 479 7.3E-34 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 SUPERFAMILY SSF52922 489 621 5.89E-28 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 SUPERFAMILY SSF52518 308 482 9.82E-48 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 SMART SM00861 318 480 1.8E-42 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 21 277 1.1E-39 T 23-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS01600 b5b31868d4869c98785697fbb7d1952e 623 ProSitePatterns PS00802 Transketolase signature 2. 423 439 - T 23-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS01635 0afdc31872957cd509cb4f4a7d7b06ab 210 Pfam PF07510 Protein of unknown function (DUF1524) 101 202 4.8E-8 T 23-04-2016 IPR011089 Domain of unknown function DUF1524 DC74_RS01635 0afdc31872957cd509cb4f4a7d7b06ab 210 PANTHER PTHR24094:SF14 18 210 1.1E-50 T 23-04-2016 DC74_RS01635 0afdc31872957cd509cb4f4a7d7b06ab 210 PANTHER PTHR24094 18 210 1.1E-50 T 23-04-2016 DC74_RS33275 8641fcb1e76057448f029e2c23d3f47f 274 SUPERFAMILY SSF53335 12 259 6.11E-38 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS33275 8641fcb1e76057448f029e2c23d3f47f 274 PIRSF PIRSF017393 3 274 3.1E-85 T 23-04-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type DC74_RS33275 8641fcb1e76057448f029e2c23d3f47f 274 Pfam PF04672 S-adenosyl methyltransferase 5 273 4.0E-82 T 23-04-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type DC74_RS33275 8641fcb1e76057448f029e2c23d3f47f 274 Gene3D G3DSA:3.40.50.150 5 273 1.0E-93 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS17315 ce1b3faf61d6542797dd8c5c6c1fc01e 389 PANTHER PTHR12526 118 384 6.2E-59 T 23-04-2016 DC74_RS17315 ce1b3faf61d6542797dd8c5c6c1fc01e 389 PANTHER PTHR12526 23 90 6.2E-59 T 23-04-2016 DC74_RS17315 ce1b3faf61d6542797dd8c5c6c1fc01e 389 SUPERFAMILY SSF53756 17 384 7.85E-69 T 23-04-2016 DC74_RS17315 ce1b3faf61d6542797dd8c5c6c1fc01e 389 Pfam PF13579 Glycosyl transferase 4-like domain 23 191 5.9E-7 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain DC74_RS17315 ce1b3faf61d6542797dd8c5c6c1fc01e 389 Pfam PF00534 Glycosyl transferases group 1 207 366 3.5E-42 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 DC74_RS17315 ce1b3faf61d6542797dd8c5c6c1fc01e 389 Gene3D G3DSA:3.40.50.2000 205 366 5.8E-29 T 23-04-2016 DC74_RS05480 d46c66157e20aae47ea451570920583c 413 PANTHER PTHR12526:SF374 1 127 3.9E-73 T 23-04-2016 DC74_RS05480 d46c66157e20aae47ea451570920583c 413 PANTHER PTHR12526:SF374 162 402 3.9E-73 T 23-04-2016 DC74_RS05480 d46c66157e20aae47ea451570920583c 413 SUPERFAMILY SSF53756 1 390 4.71E-65 T 23-04-2016 DC74_RS05480 d46c66157e20aae47ea451570920583c 413 Pfam PF13439 Glycosyltransferase Family 4 17 203 5.5E-17 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain DC74_RS05480 d46c66157e20aae47ea451570920583c 413 Pfam PF00534 Glycosyl transferases group 1 217 369 4.5E-25 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 DC74_RS05480 d46c66157e20aae47ea451570920583c 413 PANTHER PTHR12526 1 127 3.9E-73 T 23-04-2016 DC74_RS05480 d46c66157e20aae47ea451570920583c 413 PANTHER PTHR12526 162 402 3.9E-73 T 23-04-2016 DC74_RS05480 d46c66157e20aae47ea451570920583c 413 Gene3D G3DSA:3.40.50.2000 213 367 4.5E-27 T 23-04-2016 DC74_RS29105 da9f9042129e8a8dec5ac7ea807857d1 279 PANTHER PTHR11364 1 276 8.6E-83 T 23-04-2016 DC74_RS29105 da9f9042129e8a8dec5ac7ea807857d1 279 Pfam PF00581 Rhodanese-like domain 6 126 3.3E-19 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS29105 da9f9042129e8a8dec5ac7ea807857d1 279 Pfam PF00581 Rhodanese-like domain 157 266 7.7E-11 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS29105 da9f9042129e8a8dec5ac7ea807857d1 279 Gene3D G3DSA:3.40.250.10 150 277 4.5E-38 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS29105 da9f9042129e8a8dec5ac7ea807857d1 279 Gene3D G3DSA:3.40.250.10 1 147 3.8E-44 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS29105 da9f9042129e8a8dec5ac7ea807857d1 279 SUPERFAMILY SSF52821 4 146 1.7E-35 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS29105 da9f9042129e8a8dec5ac7ea807857d1 279 ProSitePatterns PS00380 Rhodanese signature 1. 38 49 - T 23-04-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 DC74_RS29105 da9f9042129e8a8dec5ac7ea807857d1 279 SMART SM00450 6 130 4.3E-27 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS29105 da9f9042129e8a8dec5ac7ea807857d1 279 SMART SM00450 151 270 1.9E-15 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS29105 da9f9042129e8a8dec5ac7ea807857d1 279 PANTHER PTHR11364:SF0 1 276 8.6E-83 T 23-04-2016 DC74_RS29105 da9f9042129e8a8dec5ac7ea807857d1 279 SUPERFAMILY SSF52821 150 276 3.14E-32 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS28115 6b917077fe1741a146a93278720d90dd 79 Hamap MF_00088 UPF0109 protein . 2 73 21.565 T 23-04-2016 IPR020627 Uncharacterised protein family UPF0109 DC74_RS28115 6b917077fe1741a146a93278720d90dd 79 Pfam PF13083 KH domain 3 64 3.2E-19 T 23-04-2016 DC74_RS28115 6b917077fe1741a146a93278720d90dd 79 SUPERFAMILY SSF54814 16 62 1.83E-8 T 23-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 DC74_RS28115 6b917077fe1741a146a93278720d90dd 79 PANTHER PTHR34654 1 79 1.9E-25 T 23-04-2016 DC74_RS28115 6b917077fe1741a146a93278720d90dd 79 Gene3D G3DSA:3.30.300.120 5 63 9.2E-6 T 23-04-2016 DC74_RS18360 0aae43226ff83c395580085272973aed 427 PANTHER PTHR11360:SF115 15 422 9.1E-157 T 23-04-2016 DC74_RS18360 0aae43226ff83c395580085272973aed 427 PANTHER PTHR11360 15 422 9.1E-157 T 23-04-2016 DC74_RS18360 0aae43226ff83c395580085272973aed 427 Gene3D G3DSA:1.20.1250.20 237 424 2.0E-16 T 23-04-2016 DC74_RS18360 0aae43226ff83c395580085272973aed 427 Gene3D G3DSA:1.20.1250.20 14 207 3.7E-26 T 23-04-2016 DC74_RS18360 0aae43226ff83c395580085272973aed 427 SUPERFAMILY SSF103473 9 421 3.92E-58 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS18360 0aae43226ff83c395580085272973aed 427 Pfam PF07690 Major Facilitator Superfamily 28 287 1.2E-23 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS33960 a1706f1048f0d4b9b171950e89231544 204 SUPERFAMILY SSF52540 17 195 3.51E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33960 a1706f1048f0d4b9b171950e89231544 204 Gene3D G3DSA:3.40.50.300 17 194 2.7E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33960 a1706f1048f0d4b9b171950e89231544 204 Pfam PF03029 Conserved hypothetical ATP binding protein 25 191 7.6E-24 T 23-04-2016 IPR004130 GPN-loop GTPase DC74_RS33960 a1706f1048f0d4b9b171950e89231544 204 PANTHER PTHR11711 21 190 9.1E-56 T 23-04-2016 DC74_RS33960 a1706f1048f0d4b9b171950e89231544 204 PANTHER PTHR11711:SF117 21 190 9.1E-56 T 23-04-2016 DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.4E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.4E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.4E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 1.4E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 1.4E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 1.4E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PANTHER PTHR24322 171 202 6.8E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PANTHER PTHR24322 55 155 6.8E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PANTHER PTHR24322 12 31 6.8E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 Pfam PF00106 short chain dehydrogenase 9 211 3.4E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 Gene3D G3DSA:3.40.50.720 5 277 4.0E-69 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 202 0.0014 T 23-04-2016 DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PANTHER PTHR24322:SF428 171 202 6.8E-44 T 23-04-2016 DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PANTHER PTHR24322:SF428 55 155 6.8E-44 T 23-04-2016 DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PANTHER PTHR24322:SF428 12 31 6.8E-44 T 23-04-2016 DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 SUPERFAMILY SSF51735 6 262 1.38E-60 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 6.2E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 6.2E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 6.2E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36385 cae1b20292963fa8a3874c352aa981f1 302 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS10960 db935395a9243362b2f3f4669adcdc21 321 PANTHER PTHR14969 29 221 4.1E-18 T 23-04-2016 DC74_RS10960 db935395a9243362b2f3f4669adcdc21 321 SUPERFAMILY SSF48317 6 204 1.31E-26 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS10960 db935395a9243362b2f3f4669adcdc21 321 Gene3D G3DSA:1.20.144.10 9 200 2.7E-18 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS10960 db935395a9243362b2f3f4669adcdc21 321 SMART SM00014 83 198 7.0E-7 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS10960 db935395a9243362b2f3f4669adcdc21 321 Pfam PF01569 PAP2 superfamily 85 201 3.8E-20 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS27060 54b7961c25e72534284d922d3f214c98 350 SUPERFAMILY SSF51735 9 123 5.25E-12 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27060 54b7961c25e72534284d922d3f214c98 350 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 8 71 2.0E-6 T 23-04-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS27060 54b7961c25e72534284d922d3f214c98 350 Gene3D G3DSA:3.40.50.720 3 162 5.9E-18 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18705 3f50810a1bf1c7b4ced6c070fe8adc92 274 SMART SM00322 59 124 1.5E-7 T 23-04-2016 IPR004087 K Homology domain GO:0003676 DC74_RS18705 3f50810a1bf1c7b4ced6c070fe8adc92 274 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 5.5E-93 T 23-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 DC74_RS18705 3f50810a1bf1c7b4ced6c070fe8adc92 274 Pfam PF07650 KH domain 38 109 4.5E-19 T 23-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 DC74_RS18705 3f50810a1bf1c7b4ced6c070fe8adc92 274 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 3.9E-37 T 23-04-2016 DC74_RS18705 3f50810a1bf1c7b4ced6c070fe8adc92 274 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.89 T 23-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 DC74_RS18705 3f50810a1bf1c7b4ced6c070fe8adc92 274 Gene3D G3DSA:3.30.300.20 17 106 3.3E-31 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta DC74_RS18705 3f50810a1bf1c7b4ced6c070fe8adc92 274 PANTHER PTHR11760:SF19 2 242 1.7E-123 T 23-04-2016 DC74_RS18705 3f50810a1bf1c7b4ced6c070fe8adc92 274 SUPERFAMILY SSF54814 2 105 2.62E-34 T 23-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 DC74_RS18705 3f50810a1bf1c7b4ced6c070fe8adc92 274 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 23-04-2016 IPR018280 Ribosomal protein S3, conserved site DC74_RS18705 3f50810a1bf1c7b4ced6c070fe8adc92 274 PANTHER PTHR11760 2 242 1.7E-123 T 23-04-2016 DC74_RS18705 3f50810a1bf1c7b4ced6c070fe8adc92 274 SUPERFAMILY SSF54821 106 205 5.23E-38 T 23-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 DC74_RS18705 3f50810a1bf1c7b4ced6c070fe8adc92 274 Gene3D G3DSA:3.30.1140.32 107 206 9.7E-43 T 23-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 DC74_RS05755 4e58ed1f96e4ba3b84539b08086201d9 341 SUPERFAMILY SSF55874 45 137 3.9E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS05755 4e58ed1f96e4ba3b84539b08086201d9 341 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 174 294 6.7E-8 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS05755 4e58ed1f96e4ba3b84539b08086201d9 341 SMART SM00331 148 336 0.0012 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS05755 4e58ed1f96e4ba3b84539b08086201d9 341 SUPERFAMILY SSF81606 150 334 8.63E-15 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS05755 4e58ed1f96e4ba3b84539b08086201d9 341 PANTHER PTHR35801:SF1 10 340 2.8E-33 T 23-04-2016 DC74_RS05755 4e58ed1f96e4ba3b84539b08086201d9 341 Gene3D G3DSA:3.30.565.10 24 133 1.3E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS05755 4e58ed1f96e4ba3b84539b08086201d9 341 PANTHER PTHR35801 10 340 2.8E-33 T 23-04-2016 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 Gene3D G3DSA:3.40.50.720 254 381 1.1E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32080 69a82a06aa69220074aff88750a68919 711 SUPERFAMILY SSF52210 381 538 7.72E-40 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 SMART SM00881 257 352 3.0E-35 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 Gene3D G3DSA:3.40.50.261 382 536 5.8E-31 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 401 538 1.2E-50 T 23-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain DC74_RS32080 69a82a06aa69220074aff88750a68919 711 Pfam PF13549 ATP-grasp domain 15 233 3.5E-76 T 23-04-2016 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 PANTHER PTHR33303 5 129 1.9E-170 T 23-04-2016 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 PANTHER PTHR33303 243 687 1.9E-170 T 23-04-2016 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 Gene3D G3DSA:3.40.50.261 537 683 1.0E-11 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 Pfam PF13380 CoA binding domain 261 379 3.4E-21 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 SUPERFAMILY SSF52210 544 689 1.7E-28 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 Gene3D G3DSA:3.30.470.20 31 143 1.2E-5 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 PANTHER PTHR33303:SF3 5 129 1.9E-170 T 23-04-2016 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 PANTHER PTHR33303:SF3 243 687 1.9E-170 T 23-04-2016 DC74_RS32080 69a82a06aa69220074aff88750a68919 711 SUPERFAMILY SSF51735 254 389 4.91E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32080 69a82a06aa69220074aff88750a68919 711 SUPERFAMILY SSF56059 31 235 4.71E-38 T 23-04-2016 DC74_RS01885 0af2ac9368ac4612122f4ac931af0372 422 Gene3D G3DSA:1.20.1250.20 227 407 1.4E-10 T 23-04-2016 DC74_RS01885 0af2ac9368ac4612122f4ac931af0372 422 Gene3D G3DSA:1.20.1250.20 18 188 6.5E-21 T 23-04-2016 DC74_RS01885 0af2ac9368ac4612122f4ac931af0372 422 PANTHER PTHR23517 12 410 4.0E-46 T 23-04-2016 DC74_RS01885 0af2ac9368ac4612122f4ac931af0372 422 PRINTS PR01035 Tetracycline resistance protein signature 169 189 4.2E-7 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 DC74_RS01885 0af2ac9368ac4612122f4ac931af0372 422 PRINTS PR01035 Tetracycline resistance protein signature 357 380 4.2E-7 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 DC74_RS01885 0af2ac9368ac4612122f4ac931af0372 422 PRINTS PR01035 Tetracycline resistance protein signature 25 41 4.2E-7 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 DC74_RS01885 0af2ac9368ac4612122f4ac931af0372 422 PRINTS PR01035 Tetracycline resistance protein signature 141 163 4.2E-7 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 DC74_RS01885 0af2ac9368ac4612122f4ac931af0372 422 SUPERFAMILY SSF103473 18 409 1.02E-41 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS01885 0af2ac9368ac4612122f4ac931af0372 422 Pfam PF07690 Major Facilitator Superfamily 22 322 2.4E-20 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS00805 8396d68fbcedb608f8cd40ce423b3f7d 110 PANTHER PTHR30055 1 107 5.0E-21 T 23-04-2016 DC74_RS00805 8396d68fbcedb608f8cd40ce423b3f7d 110 SUPERFAMILY SSF48498 2 101 1.83E-12 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS00805 8396d68fbcedb608f8cd40ce423b3f7d 110 PANTHER PTHR30055:SF19 1 107 5.0E-21 T 23-04-2016 DC74_RS00805 8396d68fbcedb608f8cd40ce423b3f7d 110 Gene3D G3DSA:1.10.357.10 2 105 4.4E-13 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 SUPERFAMILY SSF54897 61 131 7.37E-11 T 23-04-2016 IPR009020 Proteinase inhibitor, propeptide DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 356 366 - T 23-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 SUPERFAMILY SSF52743 140 405 1.15E-74 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 Gene3D G3DSA:3.30.70.80 55 135 1.4E-17 T 23-04-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 Gene3D G3DSA:3.40.50.200 139 395 3.1E-83 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 Pfam PF05922 Peptidase inhibitor I9 87 130 1.0E-8 T 23-04-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 169 180 - T 23-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 PANTHER PTHR10795 13 392 2.6E-130 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 PANTHER PTHR10795:SF389 13 392 2.6E-130 T 23-04-2016 DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 Pfam PF00082 Subtilase family 164 392 6.3E-38 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 PRINTS PR00723 Subtilisin serine protease family (S8) signature 355 371 6.8E-19 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 PRINTS PR00723 Subtilisin serine protease family (S8) signature 202 215 6.8E-19 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS10760 6e9b55d8860fe4150f0b5c5852702260 412 PRINTS PR00723 Subtilisin serine protease family (S8) signature 164 183 6.8E-19 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS18330 53db6eec02bff7ea83317e355cd0b13b 157 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 67 132 7.9E-23 T 23-04-2016 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal DC74_RS18330 53db6eec02bff7ea83317e355cd0b13b 157 PANTHER PTHR34075 7 138 2.5E-30 T 23-04-2016 DC74_RS18330 53db6eec02bff7ea83317e355cd0b13b 157 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 28 65 4.1E-11 T 23-04-2016 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DC74_RS18330 53db6eec02bff7ea83317e355cd0b13b 157 SUPERFAMILY SSF50249 16 135 8.05E-35 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS18330 53db6eec02bff7ea83317e355cd0b13b 157 PANTHER PTHR34075:SF2 7 138 2.5E-30 T 23-04-2016 DC74_RS05785 5a90ed3c0cfcb3927102eb6e4cf5e654 536 PANTHER PTHR24095 24 536 4.3E-126 T 23-04-2016 DC74_RS05785 5a90ed3c0cfcb3927102eb6e4cf5e654 536 Gene3D G3DSA:2.30.38.10 362 436 9.6E-17 T 23-04-2016 DC74_RS05785 5a90ed3c0cfcb3927102eb6e4cf5e654 536 Pfam PF00501 AMP-binding enzyme 50 441 1.2E-71 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS05785 5a90ed3c0cfcb3927102eb6e4cf5e654 536 Gene3D G3DSA:3.40.50.980 203 361 5.1E-21 T 23-04-2016 DC74_RS05785 5a90ed3c0cfcb3927102eb6e4cf5e654 536 Gene3D G3DSA:3.40.50.980 47 202 7.4E-29 T 23-04-2016 DC74_RS05785 5a90ed3c0cfcb3927102eb6e4cf5e654 536 PANTHER PTHR24095:SF180 24 536 4.3E-126 T 23-04-2016 DC74_RS05785 5a90ed3c0cfcb3927102eb6e4cf5e654 536 Gene3D G3DSA:3.30.300.30 446 535 1.7E-18 T 23-04-2016 DC74_RS05785 5a90ed3c0cfcb3927102eb6e4cf5e654 536 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 530 1.6E-16 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS05785 5a90ed3c0cfcb3927102eb6e4cf5e654 536 SUPERFAMILY SSF56801 12 535 1.31E-117 T 23-04-2016 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 Gene3D G3DSA:2.40.30.10 87 186 1.4E-25 T 23-04-2016 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 Pfam PF00175 Oxidoreductase NAD-binding domain 198 295 2.8E-5 T 23-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 Gene3D G3DSA:3.40.50.80 191 309 3.8E-25 T 23-04-2016 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 SUPERFAMILY SSF52343 184 320 9.17E-27 T 23-04-2016 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 SUPERFAMILY SSF63380 88 186 1.13E-20 T 23-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 PANTHER PTHR19370:SF113 86 332 4.0E-57 T 23-04-2016 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 PANTHER PTHR19370:SF113 36 57 4.0E-57 T 23-04-2016 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 SUPERFAMILY SSF54292 307 413 1.7E-22 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 PRINTS PR00409 Phthalate dioxygenase reductase family signature 111 121 6.0E-23 T 23-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 PRINTS PR00409 Phthalate dioxygenase reductase family signature 197 216 6.0E-23 T 23-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 PRINTS PR00409 Phthalate dioxygenase reductase family signature 121 133 6.0E-23 T 23-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 PRINTS PR00409 Phthalate dioxygenase reductase family signature 222 231 6.0E-23 T 23-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 PRINTS PR00409 Phthalate dioxygenase reductase family signature 281 289 6.0E-23 T 23-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 PRINTS PR00409 Phthalate dioxygenase reductase family signature 133 147 6.0E-23 T 23-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 PANTHER PTHR19370 86 332 4.0E-57 T 23-04-2016 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 PANTHER PTHR19370 36 57 4.0E-57 T 23-04-2016 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 Gene3D G3DSA:3.10.20.30 310 411 9.1E-24 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 369 377 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS13210 b52d2bfd6ec3b836a51099c8ef3958e7 419 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 340 409 1.3E-11 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS06860 17f3e2297bfb01a258172361c261eada 342 PANTHER PTHR10366:SF32 4 333 9.2E-165 T 23-04-2016 DC74_RS06860 17f3e2297bfb01a258172361c261eada 342 Gene3D G3DSA:3.40.50.720 3 203 7.8E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06860 17f3e2297bfb01a258172361c261eada 342 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 330 50.246 T 23-04-2016 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|UniPathway: UPA00128 DC74_RS06860 17f3e2297bfb01a258172361c261eada 342 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 320 2.3E-118 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06860 17f3e2297bfb01a258172361c261eada 342 Gene3D G3DSA:3.90.25.10 204 332 1.4E-45 T 23-04-2016 DC74_RS06860 17f3e2297bfb01a258172361c261eada 342 SUPERFAMILY SSF51735 3 327 5.89E-73 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06860 17f3e2297bfb01a258172361c261eada 342 PANTHER PTHR10366 4 333 9.2E-165 T 23-04-2016 DC74_RS11655 97d1de12bd6ed7c3df6e47c8d012e789 90 PANTHER PTHR33884 1 88 4.4E-23 T 23-04-2016 DC74_RS11655 97d1de12bd6ed7c3df6e47c8d012e789 90 Pfam PF04226 Transglycosylase associated protein 33 83 1.6E-9 T 23-04-2016 IPR007341 Transglycosylase-associated protein GO:0016021 DC74_RS10805 b6de12719172848d22e60fd1c53065cb 333 SUPERFAMILY SSF81296 31 210 2.94E-49 T 23-04-2016 IPR014756 Immunoglobulin E-set DC74_RS10805 b6de12719172848d22e60fd1c53065cb 333 PANTHER PTHR34823 1 212 4.0E-73 T 23-04-2016 DC74_RS10805 b6de12719172848d22e60fd1c53065cb 333 Gene3D G3DSA:2.70.50.50 31 210 3.5E-53 T 23-04-2016 DC74_RS10805 b6de12719172848d22e60fd1c53065cb 333 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 207 1.2E-42 T 23-04-2016 IPR004302 Chitin-binding protein, N-terminal DC74_RS10805 b6de12719172848d22e60fd1c53065cb 333 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 295 329 0.0024 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain DC74_RS10805 b6de12719172848d22e60fd1c53065cb 333 PANTHER PTHR34823:SF2 1 212 4.0E-73 T 23-04-2016 DC74_RS26560 a063ed463591f1eabe6155cc45ea4bbd 510 Gene3D G3DSA:1.20.1250.20 20 211 2.0E-28 T 23-04-2016 DC74_RS26560 a063ed463591f1eabe6155cc45ea4bbd 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 29 53 2.8E-8 T 23-04-2016 DC74_RS26560 a063ed463591f1eabe6155cc45ea4bbd 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 2.8E-8 T 23-04-2016 DC74_RS26560 a063ed463591f1eabe6155cc45ea4bbd 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 120 140 2.8E-8 T 23-04-2016 DC74_RS26560 a063ed463591f1eabe6155cc45ea4bbd 510 Pfam PF07690 Major Facilitator Superfamily 31 432 1.3E-49 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS26560 a063ed463591f1eabe6155cc45ea4bbd 510 PANTHER PTHR23501 6 482 1.2E-185 T 23-04-2016 DC74_RS26560 a063ed463591f1eabe6155cc45ea4bbd 510 PANTHER PTHR23501:SF31 6 482 1.2E-185 T 23-04-2016 DC74_RS26560 a063ed463591f1eabe6155cc45ea4bbd 510 SUPERFAMILY SSF103473 267 482 3.4E-63 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS26560 a063ed463591f1eabe6155cc45ea4bbd 510 SUPERFAMILY SSF103473 1 216 3.4E-63 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS26560 a063ed463591f1eabe6155cc45ea4bbd 510 Gene3D G3DSA:1.20.1250.20 284 480 5.4E-12 T 23-04-2016 DC74_RS37770 748ceccb6d5d59e49afd25408a064413 107 PANTHER PTHR33336 1 102 8.8E-25 T 23-04-2016 DC74_RS37770 748ceccb6d5d59e49afd25408a064413 107 SUPERFAMILY SSF54909 1 93 1.03E-26 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS37770 748ceccb6d5d59e49afd25408a064413 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 6.1E-18 T 23-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain DC74_RS37770 748ceccb6d5d59e49afd25408a064413 107 Gene3D G3DSA:3.30.70.900 1 90 3.6E-24 T 23-04-2016 DC74_RS19090 2e9d80f58ac6bd555ae4b2b7167cc13f 284 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 26 264 6.4E-42 T 23-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 DC74_RS19090 2e9d80f58ac6bd555ae4b2b7167cc13f 284 PANTHER PTHR21581:SF3 26 284 5.8E-61 T 23-04-2016 DC74_RS19090 2e9d80f58ac6bd555ae4b2b7167cc13f 284 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 56 67 1.5E-13 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 DC74_RS19090 2e9d80f58ac6bd555ae4b2b7167cc13f 284 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 144 157 1.5E-13 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 DC74_RS19090 2e9d80f58ac6bd555ae4b2b7167cc13f 284 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 111 128 1.5E-13 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 DC74_RS19090 2e9d80f58ac6bd555ae4b2b7167cc13f 284 Gene3D G3DSA:3.40.710.10 25 283 1.4E-79 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS19090 2e9d80f58ac6bd555ae4b2b7167cc13f 284 PANTHER PTHR21581 26 284 5.8E-61 T 23-04-2016 DC74_RS19090 2e9d80f58ac6bd555ae4b2b7167cc13f 284 SUPERFAMILY SSF56601 26 282 7.05E-58 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS02440 bd6e4cc37f7d2ee80518204008875ee5 272 Gene3D G3DSA:3.40.50.720 111 239 7.1E-9 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02440 bd6e4cc37f7d2ee80518204008875ee5 272 Pfam PF02625 XdhC and CoxI family 14 73 1.2E-14 T 23-04-2016 IPR003777 XdhC- CoxI DC74_RS02440 bd6e4cc37f7d2ee80518204008875ee5 272 SUPERFAMILY SSF51735 112 187 4.63E-7 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02440 bd6e4cc37f7d2ee80518204008875ee5 272 PANTHER PTHR30388 3 272 4.2E-123 T 23-04-2016 DC74_RS02440 bd6e4cc37f7d2ee80518204008875ee5 272 PANTHER PTHR30388:SF5 3 272 4.2E-123 T 23-04-2016 DC74_RS02440 bd6e4cc37f7d2ee80518204008875ee5 272 TIGRFAM TIGR02964 xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC 21 264 3.7E-76 T 23-04-2016 IPR014308 Xanthine dehydrogenase accessory protein XdhC DC74_RS02440 bd6e4cc37f7d2ee80518204008875ee5 272 Pfam PF13478 XdhC Rossmann domain 112 263 2.5E-33 T 23-04-2016 IPR027051 XdhC Rossmann domain DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 Gene3D G3DSA:3.40.50.1700 337 585 8.2E-72 T 23-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 SUPERFAMILY SSF52279 350 585 9.42E-56 T 23-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 Pfam PF14310 Fibronectin type III-like domain 624 695 2.8E-22 T 23-04-2016 IPR026891 Fibronectin type III-like domain DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 PANTHER PTHR30620:SF5 1 17 1.2E-287 T 23-04-2016 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 PANTHER PTHR30620:SF5 39 706 1.2E-287 T 23-04-2016 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 PRINTS PR00133 Glycosyl hydrolase family 3 signature 164 180 1.4E-22 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 PRINTS PR00133 Glycosyl hydrolase family 3 signature 81 100 1.4E-22 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 PRINTS PR00133 Glycosyl hydrolase family 3 signature 234 252 1.4E-22 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 PRINTS PR00133 Glycosyl hydrolase family 3 signature 62 78 1.4E-22 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 PRINTS PR00133 Glycosyl hydrolase family 3 signature 127 143 1.4E-22 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 SUPERFAMILY SSF51445 1 349 1.26E-103 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 SMART SM01217 624 695 5.7E-31 T 23-04-2016 IPR026891 Fibronectin type III-like domain DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 234 251 - T 23-04-2016 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 PANTHER PTHR30620 1 17 1.2E-287 T 23-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 PANTHER PTHR30620 39 706 1.2E-287 T 23-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 Gene3D G3DSA:3.20.20.300 1 328 1.0E-108 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 350 582 2.3E-54 T 23-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 DC74_RS34265 3b8c249e9348894208ef6947acfb06ee 706 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 2 313 4.3E-78 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS34045 3c5aaa5c31db7202077938800d3fad4e 615 Gene3D G3DSA:1.20.1560.10 22 342 6.2E-66 T 23-04-2016 DC74_RS34045 3c5aaa5c31db7202077938800d3fad4e 615 SUPERFAMILY SSF52540 347 590 7.35E-91 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34045 3c5aaa5c31db7202077938800d3fad4e 615 SUPERFAMILY SSF90123 22 343 3.01E-67 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS34045 3c5aaa5c31db7202077938800d3fad4e 615 SMART SM00382 382 568 1.1E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS34045 3c5aaa5c31db7202077938800d3fad4e 615 Pfam PF00005 ABC transporter 373 522 8.7E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS34045 3c5aaa5c31db7202077938800d3fad4e 615 Gene3D G3DSA:3.40.50.300 356 587 7.9E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34045 3c5aaa5c31db7202077938800d3fad4e 615 Pfam PF00664 ABC transporter transmembrane region 36 308 3.1E-37 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS34045 3c5aaa5c31db7202077938800d3fad4e 615 ProSitePatterns PS00211 ABC transporters family signature. 494 508 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS34045 3c5aaa5c31db7202077938800d3fad4e 615 PANTHER PTHR24221:SF161 5 603 4.0E-220 T 23-04-2016 DC74_RS34045 3c5aaa5c31db7202077938800d3fad4e 615 PANTHER PTHR24221 5 603 4.0E-220 T 23-04-2016 DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.1E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.1E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.1E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 PANTHER PTHR24322 19 147 3.5E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 PANTHER PTHR24322 163 195 3.5E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 194 1.1E-4 T 23-04-2016 DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 Gene3D G3DSA:3.40.50.720 9 257 3.8E-84 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 5.8E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 5.8E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 5.8E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 5.8E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 5.8E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 5.8E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 256 4.7E-60 T 23-04-2016 DC74_RS09000 523fd9226c0e44ea0edce0b400452438 258 SUPERFAMILY SSF51735 10 257 1.13E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32295 6dc23ae9e48e77b85bea49a7b5d1e3d3 423 PANTHER PTHR11712 4 418 7.3E-135 T 23-04-2016 DC74_RS32295 6dc23ae9e48e77b85bea49a7b5d1e3d3 423 SMART SM00825 Beta-ketoacyl synthase 6 409 3.3E-15 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS32295 6dc23ae9e48e77b85bea49a7b5d1e3d3 423 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 253 1.0E-53 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS32295 6dc23ae9e48e77b85bea49a7b5d1e3d3 423 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 161 177 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS32295 6dc23ae9e48e77b85bea49a7b5d1e3d3 423 Gene3D G3DSA:3.40.47.10 271 417 3.3E-53 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS32295 6dc23ae9e48e77b85bea49a7b5d1e3d3 423 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 375 3.2E-35 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS32295 6dc23ae9e48e77b85bea49a7b5d1e3d3 423 SUPERFAMILY SSF53901 4 258 1.79E-64 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS32295 6dc23ae9e48e77b85bea49a7b5d1e3d3 423 SUPERFAMILY SSF53901 220 418 5.4E-68 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS32295 6dc23ae9e48e77b85bea49a7b5d1e3d3 423 Gene3D G3DSA:3.40.47.10 4 264 2.0E-68 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 SUPERFAMILY SSF54991 744 840 1.7E-26 T 23-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 SMART SM00896 747 840 1.3E-40 T 23-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 Pfam PF01588 Putative tRNA binding domain 48 154 8.2E-21 T 23-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 Gene3D G3DSA:3.30.930.10 503 734 4.5E-62 T 23-04-2016 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 834 40.239 T 23-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 SUPERFAMILY SSF46955 421 492 1.01E-14 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 Gene3D G3DSA:3.30.70.380 749 840 1.8E-29 T 23-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 840 1.1E-184 T 23-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 Gene3D G3DSA:3.30.56.20 421 492 1.4E-21 T 23-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 Gene3D G3DSA:3.30.56.10 1 40 8.1E-18 T 23-04-2016 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 Gene3D G3DSA:3.30.56.10 164 192 8.1E-18 T 23-04-2016 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 SUPERFAMILY SSF50249 47 204 2.03E-32 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 Gene3D G3DSA:2.40.50.140 45 162 1.2E-39 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 SUPERFAMILY SSF56037 211 413 2.62E-63 T 23-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 SMART SM00873 221 405 4.1E-81 T 23-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 Pfam PF03484 tRNA synthetase B5 domain 423 488 1.8E-16 T 23-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 Pfam PF03147 Ferredoxin-fold anticodon binding domain 747 840 8.9E-25 T 23-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 Gene3D G3DSA:3.50.40.10 211 414 8.4E-81 T 23-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 SUPERFAMILY SSF55681 484 600 2.15E-43 T 23-04-2016 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 SUPERFAMILY SSF55681 630 733 2.15E-43 T 23-04-2016 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 PANTHER PTHR10947:SF0 2 602 2.6E-269 T 23-04-2016 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 PANTHER PTHR10947:SF0 624 840 2.6E-269 T 23-04-2016 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 PANTHER PTHR10947 2 602 2.6E-269 T 23-04-2016 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 PANTHER PTHR10947 624 840 2.6E-269 T 23-04-2016 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 SMART SM00874 421 488 5.4E-21 T 23-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 DC74_RS10080 6677eb09158a756051ab7b15948b30e2 841 Pfam PF03483 B3/4 domain 221 405 1.5E-66 T 23-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 DC74_RS17495 45b143dc5f5b4d33c9bc74185c5c086d 324 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 1.3E-44 T 23-04-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 DC74_RS17495 45b143dc5f5b4d33c9bc74185c5c086d 324 SUPERFAMILY SSF53271 77 313 2.38E-61 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS17495 45b143dc5f5b4d33c9bc74185c5c086d 324 Gene3D G3DSA:3.40.50.2020 9 167 2.7E-68 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS17495 45b143dc5f5b4d33c9bc74185c5c086d 324 Pfam PF14572 Phosphoribosyl synthetase-associated domain 215 321 2.2E-24 T 23-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 DC74_RS17495 45b143dc5f5b4d33c9bc74185c5c086d 324 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 23-04-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 DC74_RS17495 45b143dc5f5b4d33c9bc74185c5c086d 324 SMART SM01400 12 128 8.4E-71 T 23-04-2016 DC74_RS17495 45b143dc5f5b4d33c9bc74185c5c086d 324 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 322 4.1E-114 T 23-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 DC74_RS17495 45b143dc5f5b4d33c9bc74185c5c086d 324 Gene3D G3DSA:3.40.50.2020 168 294 3.3E-47 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS17495 45b143dc5f5b4d33c9bc74185c5c086d 324 PANTHER PTHR10210:SF41 1 323 9.2E-174 T 23-04-2016 DC74_RS17495 45b143dc5f5b4d33c9bc74185c5c086d 324 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 322 46.728 T 23-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 DC74_RS17495 45b143dc5f5b4d33c9bc74185c5c086d 324 PANTHER PTHR10210 1 323 9.2E-174 T 23-04-2016 DC74_RS04815 759f33f99c8cd1eb3264828dff45e9d6 609 Gene3D G3DSA:1.50.10.10 226 601 1.2E-87 T 23-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 DC74_RS04815 759f33f99c8cd1eb3264828dff45e9d6 609 Pfam PF00723 Glycosyl hydrolases family 15 545 593 1.8E-5 T 23-04-2016 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: REACT_474 DC74_RS04815 759f33f99c8cd1eb3264828dff45e9d6 609 Pfam PF00723 Glycosyl hydrolases family 15 246 539 5.9E-45 T 23-04-2016 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: REACT_474 DC74_RS04815 759f33f99c8cd1eb3264828dff45e9d6 609 SUPERFAMILY SSF48208 215 599 1.85E-93 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 DC74_RS04815 759f33f99c8cd1eb3264828dff45e9d6 609 PANTHER PTHR31616:SF0 2 609 4.9E-163 T 23-04-2016 DC74_RS04815 759f33f99c8cd1eb3264828dff45e9d6 609 PANTHER PTHR31616 2 609 4.9E-163 T 23-04-2016 DC74_RS35740 ffe41221ce889dc297d5b6ae99651fe2 135 SUPERFAMILY SSF51735 8 80 3.94E-14 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS35740 ffe41221ce889dc297d5b6ae99651fe2 135 Gene3D G3DSA:3.40.50.720 8 65 3.7E-7 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS35740 ffe41221ce889dc297d5b6ae99651fe2 135 PANTHER PTHR14194 3 133 2.8E-32 T 23-04-2016 DC74_RS35740 ffe41221ce889dc297d5b6ae99651fe2 135 PANTHER PTHR14194:SF59 3 133 2.8E-32 T 23-04-2016 DC74_RS06175 4298f016a28c14098b001ebf4cb19ed2 318 Gene3D G3DSA:2.130.10.130 168 302 2.8E-9 T 23-04-2016 DC74_RS06175 4298f016a28c14098b001ebf4cb19ed2 318 SUPERFAMILY SSF69318 73 311 2.09E-17 T 23-04-2016 DC74_RS06175 4298f016a28c14098b001ebf4cb19ed2 318 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 216 279 4.2E-9 T 23-04-2016 DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 PANTHER PTHR24095:SF137 4 596 4.2E-178 T 23-04-2016 DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 Pfam PF00501 AMP-binding enzyme 11 394 1.3E-95 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 30 417 2.6E-127 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 Gene3D G3DSA:3.30.300.30 389 509 1.0E-29 T 23-04-2016 DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 ProSitePatterns PS00455 Putative AMP-binding domain signature. 146 157 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 SMART SM00823 Phosphopantetheine attachment site 505 576 2.5E-5 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 Gene3D G3DSA:1.10.1200.10 510 577 1.4E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 Pfam PF13193 AMP-binding enzyme C-terminal domain 402 479 3.5E-11 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 Gene3D G3DSA:3.40.50.980 3 154 7.4E-45 T 23-04-2016 DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 SUPERFAMILY SSF47336 502 583 9.81E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 ProSitePatterns PS00012 Phosphopantetheine attachment site. 531 546 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 Gene3D G3DSA:3.40.50.980 155 306 1.8E-34 T 23-04-2016 DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 Pfam PF00550 Phosphopantetheine attachment site 507 572 1.3E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 SUPERFAMILY SSF56801 3 518 1.57E-140 T 23-04-2016 DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 PANTHER PTHR24095 4 596 4.2E-178 T 23-04-2016 DC74_RS05990 9384d4c492295d1dd9fc44fcbd4170bc 606 Gene3D G3DSA:2.30.38.10 307 384 4.4E-27 T 23-04-2016 DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 Pfam PF10502 Signal peptidase, peptidase S26 137 225 4.8E-6 T 23-04-2016 IPR019533 Peptidase S26 DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 Gene3D G3DSA:2.10.109.10 54 147 1.5E-38 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 Gene3D G3DSA:2.10.109.10 185 237 1.5E-38 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 185 204 2.1E-21 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 137 149 2.1E-21 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 57 73 2.1E-21 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 ProSitePatterns PS00761 Signal peptidases I signature 3. 190 203 - T 23-04-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 42 232 3.3E-37 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 PANTHER PTHR12383 39 103 1.5E-57 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 PANTHER PTHR12383 135 247 1.5E-57 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 SUPERFAMILY SSF51306 57 104 3.14E-47 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 SUPERFAMILY SSF51306 132 237 3.14E-47 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 Pfam PF00717 Peptidase S24-like 64 102 4.4E-9 T 23-04-2016 IPR019759 Peptidase S24/S26A/S26B DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 PANTHER PTHR12383:SF14 39 103 1.5E-57 T 23-04-2016 DC74_RS28135 8c522073c7e764ea2dc8a8a33b8bac1d 254 PANTHER PTHR12383:SF14 135 247 1.5E-57 T 23-04-2016 DC74_RS27610 ee7f1f476af097cf628daf973807daba 301 Gene3D G3DSA:3.20.20.30 25 297 3.5E-29 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS27610 ee7f1f476af097cf628daf973807daba 301 Pfam PF00296 Luciferase-like monooxygenase 21 274 1.4E-24 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS27610 ee7f1f476af097cf628daf973807daba 301 SUPERFAMILY SSF51679 13 295 3.53E-41 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS27610 ee7f1f476af097cf628daf973807daba 301 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 10 298 3.7E-105 T 23-04-2016 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted DC74_RS16500 7241a49b63dcd242c9904955c71b69ba 155 PANTHER PTHR30154:SF12 3 155 5.7E-62 T 23-04-2016 DC74_RS16500 7241a49b63dcd242c9904955c71b69ba 155 Gene3D G3DSA:1.10.10.10 3 53 1.8E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16500 7241a49b63dcd242c9904955c71b69ba 155 PANTHER PTHR30154 3 155 5.7E-62 T 23-04-2016 DC74_RS16500 7241a49b63dcd242c9904955c71b69ba 155 SUPERFAMILY SSF54909 63 148 2.15E-17 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS16500 7241a49b63dcd242c9904955c71b69ba 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 4.9E-10 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS16500 7241a49b63dcd242c9904955c71b69ba 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 4.9E-10 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS16500 7241a49b63dcd242c9904955c71b69ba 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 4.9E-10 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS16500 7241a49b63dcd242c9904955c71b69ba 155 SUPERFAMILY SSF46785 2 63 2.18E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16500 7241a49b63dcd242c9904955c71b69ba 155 Pfam PF01037 Lrp/AsnC ligand binding domain 72 138 9.2E-14 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS16500 7241a49b63dcd242c9904955c71b69ba 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 5.5E-10 T 23-04-2016 DC74_RS16500 7241a49b63dcd242c9904955c71b69ba 155 Gene3D G3DSA:3.30.70.920 56 139 1.6E-18 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS16500 7241a49b63dcd242c9904955c71b69ba 155 SMART SM00344 3 109 2.9E-27 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS08885 547cafe5856a19b4e26b0ef94189b0e0 346 PANTHER PTHR30146 15 346 2.7E-188 T 23-04-2016 DC74_RS08885 547cafe5856a19b4e26b0ef94189b0e0 346 Gene3D G3DSA:1.10.260.40 15 65 1.4E-21 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS08885 547cafe5856a19b4e26b0ef94189b0e0 346 ProSitePatterns PS00356 LacI-type HTH domain signature. 18 36 - T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS08885 547cafe5856a19b4e26b0ef94189b0e0 346 SUPERFAMILY SSF53822 75 338 4.38E-62 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS08885 547cafe5856a19b4e26b0ef94189b0e0 346 PANTHER PTHR30146:SF41 15 346 2.7E-188 T 23-04-2016 DC74_RS08885 547cafe5856a19b4e26b0ef94189b0e0 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 62 2.1E-13 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS08885 547cafe5856a19b4e26b0ef94189b0e0 346 Gene3D G3DSA:3.40.50.2300 187 319 1.2E-41 T 23-04-2016 DC74_RS08885 547cafe5856a19b4e26b0ef94189b0e0 346 SMART SM00354 15 85 1.9E-23 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS08885 547cafe5856a19b4e26b0ef94189b0e0 346 SUPERFAMILY SSF47413 15 73 2.81E-15 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS08885 547cafe5856a19b4e26b0ef94189b0e0 346 Gene3D G3DSA:3.40.50.2300 66 186 1.6E-39 T 23-04-2016 DC74_RS08885 547cafe5856a19b4e26b0ef94189b0e0 346 Pfam PF13377 Periplasmic binding protein-like domain 182 338 6.7E-31 T 23-04-2016 DC74_RS13820 e2c21f8e4dcd299f8b6cbfbdaf1884b6 212 Pfam PF09335 SNARE associated Golgi protein 65 171 1.4E-9 T 23-04-2016 IPR032816 SNARE associated Golgi protein DC74_RS13820 e2c21f8e4dcd299f8b6cbfbdaf1884b6 212 PANTHER PTHR30353 13 202 1.5E-20 T 23-04-2016 IPR032818 DedA family DC74_RS00400 87b16b990b2a6cb2bfd85d13155683cf 198 Gene3D G3DSA:1.10.357.10 62 189 1.7E-31 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS00400 87b16b990b2a6cb2bfd85d13155683cf 198 Gene3D G3DSA:1.10.10.60 12 60 6.1E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00400 87b16b990b2a6cb2bfd85d13155683cf 198 SUPERFAMILY SSF46689 13 71 2.1E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00400 87b16b990b2a6cb2bfd85d13155683cf 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 66 1.8E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00400 87b16b990b2a6cb2bfd85d13155683cf 198 PANTHER PTHR30055:SF67 5 189 3.7E-75 T 23-04-2016 DC74_RS00400 87b16b990b2a6cb2bfd85d13155683cf 198 PANTHER PTHR30055 5 189 3.7E-75 T 23-04-2016 DC74_RS00400 87b16b990b2a6cb2bfd85d13155683cf 198 Pfam PF16859 Bacterial transcriptional repressor C-terminal 80 187 1.3E-25 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS00400 87b16b990b2a6cb2bfd85d13155683cf 198 SUPERFAMILY SSF48498 80 191 1.84E-22 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS23750 60bb47b0cef99ad5ae8d0194f809ac87 432 PANTHER PTHR11712 23 418 2.6E-78 T 23-04-2016 DC74_RS23750 60bb47b0cef99ad5ae8d0194f809ac87 432 Gene3D G3DSA:1.10.630.10 19 416 3.0E-83 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS23750 60bb47b0cef99ad5ae8d0194f809ac87 432 PRINTS PR00359 B-class P450 signature 352 361 7.6E-23 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23750 60bb47b0cef99ad5ae8d0194f809ac87 432 PRINTS PR00359 B-class P450 signature 157 173 7.6E-23 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23750 60bb47b0cef99ad5ae8d0194f809ac87 432 PRINTS PR00359 B-class P450 signature 286 297 7.6E-23 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23750 60bb47b0cef99ad5ae8d0194f809ac87 432 PRINTS PR00359 B-class P450 signature 111 122 7.6E-23 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23750 60bb47b0cef99ad5ae8d0194f809ac87 432 PRINTS PR00359 B-class P450 signature 208 230 7.6E-23 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23750 60bb47b0cef99ad5ae8d0194f809ac87 432 PRINTS PR00359 B-class P450 signature 304 331 7.6E-23 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS23750 60bb47b0cef99ad5ae8d0194f809ac87 432 PANTHER PTHR11712:SF234 23 418 2.6E-78 T 23-04-2016 DC74_RS23750 60bb47b0cef99ad5ae8d0194f809ac87 432 SUPERFAMILY SSF48264 21 416 9.95E-58 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 Hamap MF_01953 Urease subunit alpha [ureC]. 2 573 55.226 T 23-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 573 1.6E-266 T 23-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 PANTHER PTHR22642 327 507 3.3E-231 T 23-04-2016 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 PANTHER PTHR22642 44 303 3.3E-231 T 23-04-2016 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 407 422 3.7E-32 T 23-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 302 319 3.7E-32 T 23-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 433 446 3.7E-32 T 23-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 341 357 3.7E-32 T 23-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 Gene3D G3DSA:3.20.20.140 494 571 5.9E-194 T 23-04-2016 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 Gene3D G3DSA:3.20.20.140 151 435 5.9E-194 T 23-04-2016 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 Gene3D G3DSA:2.30.40.10 72 150 3.5E-14 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 Pfam PF01979 Amidohydrolase family 132 458 3.3E-70 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 ProSitePatterns PS00145 Urease active site. 324 340 - T 23-04-2016 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 126 1.7E-52 T 23-04-2016 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 SUPERFAMILY SSF51338 2 183 1.1E-55 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 PANTHER PTHR22642:SF7 327 507 3.3E-231 T 23-04-2016 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 PANTHER PTHR22642:SF7 44 303 3.3E-231 T 23-04-2016 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 ProSitePatterns PS01120 Urease nickel ligands signature. 134 147 - T 23-04-2016 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 SUPERFAMILY SSF51338 415 485 5.98E-11 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 SUPERFAMILY SSF51556 487 573 4.75E-185 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS35615 38f3471ae71c8f3a2b311df89fbac185 573 SUPERFAMILY SSF51556 136 438 4.75E-185 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS08900 cebffd556002194f445ece29e5eb736c 320 Gene3D G3DSA:3.40.50.1220 190 315 1.7E-57 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS08900 cebffd556002194f445ece29e5eb736c 320 PANTHER PTHR10909 148 314 4.4E-56 T 23-04-2016 DC74_RS08900 cebffd556002194f445ece29e5eb736c 320 PANTHER PTHR10909:SF294 148 314 4.4E-56 T 23-04-2016 DC74_RS08900 cebffd556002194f445ece29e5eb736c 320 SMART SM00893 4 187 1.8E-25 T 23-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 DC74_RS08900 cebffd556002194f445ece29e5eb736c 320 PIRSF PIRSF000089 1 320 1.3E-97 T 23-04-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 DC74_RS08900 cebffd556002194f445ece29e5eb736c 320 SUPERFAMILY SSF52402 3 187 7.67E-35 T 23-04-2016 DC74_RS08900 cebffd556002194f445ece29e5eb736c 320 SUPERFAMILY SSF52467 194 314 1.01E-46 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS08900 cebffd556002194f445ece29e5eb736c 320 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 259 285 - T 23-04-2016 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site DC74_RS08900 cebffd556002194f445ece29e5eb736c 320 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 196 278 1.1E-35 T 23-04-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal DC74_RS08900 cebffd556002194f445ece29e5eb736c 320 Gene3D G3DSA:3.40.50.620 3 185 1.0E-37 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS08900 cebffd556002194f445ece29e5eb736c 320 Pfam PF01012 Electron transfer flavoprotein domain 4 175 2.5E-28 T 23-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 DC74_RS17675 41977c823f02d9d977880ee260d60fff 257 Gene3D G3DSA:3.40.50.300 9 234 1.8E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17675 41977c823f02d9d977880ee260d60fff 257 PANTHER PTHR24220:SF66 14 256 3.2E-91 T 23-04-2016 DC74_RS17675 41977c823f02d9d977880ee260d60fff 257 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS17675 41977c823f02d9d977880ee260d60fff 257 Pfam PF00005 ABC transporter 31 174 3.8E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS17675 41977c823f02d9d977880ee260d60fff 257 SMART SM00382 38 227 3.1E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS17675 41977c823f02d9d977880ee260d60fff 257 SUPERFAMILY SSF52540 12 233 1.22E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17675 41977c823f02d9d977880ee260d60fff 257 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 22 203 4.7E-64 T 23-04-2016 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 DC74_RS17675 41977c823f02d9d977880ee260d60fff 257 PANTHER PTHR24220 14 256 3.2E-91 T 23-04-2016 DC74_RS35075 be4eb0f6ebb0f911fcc2096d9405e2b6 152 Gene3D G3DSA:3.10.129.10 11 151 1.8E-39 T 23-04-2016 IPR029069 HotDog domain DC74_RS35075 be4eb0f6ebb0f911fcc2096d9405e2b6 152 Pfam PF14539 Domain of unknown function (DUF4442) 12 147 5.7E-27 T 23-04-2016 IPR027961 Protein of unknown function DUF4442 DC74_RS35075 be4eb0f6ebb0f911fcc2096d9405e2b6 152 SUPERFAMILY SSF54637 6 150 2.67E-20 T 23-04-2016 IPR029069 HotDog domain DC74_RS02780 83d2b3248a348ac3c67fed3954118f4a 407 SUPERFAMILY SSF55874 305 405 7.6E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS02780 83d2b3248a348ac3c67fed3954118f4a 407 Pfam PF07730 Histidine kinase 219 285 1.6E-13 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS02780 83d2b3248a348ac3c67fed3954118f4a 407 PANTHER PTHR24421 194 407 7.1E-83 T 23-04-2016 DC74_RS02780 83d2b3248a348ac3c67fed3954118f4a 407 Pfam PF13796 Putative sensor 29 191 2.9E-29 T 23-04-2016 IPR025828 Putative sensor domain DC74_RS02780 83d2b3248a348ac3c67fed3954118f4a 407 PANTHER PTHR24421:SF19 194 407 7.1E-83 T 23-04-2016 DC74_RS02780 83d2b3248a348ac3c67fed3954118f4a 407 Gene3D G3DSA:3.30.565.10 319 406 5.0E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS37050 7257abe00feeef58862fa4f1af13394a 171 SUPERFAMILY SSF52309 62 123 5.49E-9 T 23-04-2016 DC74_RS37050 7257abe00feeef58862fa4f1af13394a 171 Gene3D G3DSA:3.40.50.1810 70 123 2.0E-5 T 23-04-2016 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 DC74_RS37050 7257abe00feeef58862fa4f1af13394a 171 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 61 122 9.3E-7 T 23-04-2016 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 DC74_RS10895 a9782b0f5ac3f53f0ef9db4f7896d295 310 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 86 148 3.3E-16 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 DC74_RS10895 a9782b0f5ac3f53f0ef9db4f7896d295 310 PANTHER PTHR30450 69 310 1.3E-75 T 23-04-2016 DC74_RS10895 a9782b0f5ac3f53f0ef9db4f7896d295 310 PANTHER PTHR30450:SF2 69 310 1.3E-75 T 23-04-2016 DC74_RS10895 a9782b0f5ac3f53f0ef9db4f7896d295 310 Gene3D G3DSA:1.10.3720.10 81 304 4.9E-48 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS10895 a9782b0f5ac3f53f0ef9db4f7896d295 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 303 1.8E-23 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS10895 a9782b0f5ac3f53f0ef9db4f7896d295 310 SUPERFAMILY SSF161098 86 296 1.57E-43 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 Gene3D G3DSA:3.20.70.20 159 356 1.2E-77 T 23-04-2016 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 Gene3D G3DSA:3.20.70.20 617 662 1.2E-77 T 23-04-2016 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 Gene3D G3DSA:3.20.70.20 406 571 1.2E-77 T 23-04-2016 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 606 628 - T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 PANTHER PTHR11573 33 806 0.0 T 23-04-2016 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 SUPERFAMILY SSF51998 697 767 6.71E-172 T 23-04-2016 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 SUPERFAMILY SSF51998 233 666 6.71E-172 T 23-04-2016 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 154 230 2.6E-19 T 23-04-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 157 766 9.9E-224 T 23-04-2016 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 Pfam PF02867 Ribonucleotide reductase, barrel domain 234 762 2.7E-173 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 SUPERFAMILY SSF48168 33 232 2.22E-41 T 23-04-2016 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 PANTHER PTHR11573:SF6 33 806 0.0 T 23-04-2016 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 PRINTS PR01183 Ribonucleotide reductase large chain signature 551 574 1.5E-48 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 PRINTS PR01183 Ribonucleotide reductase large chain signature 310 329 1.5E-48 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 PRINTS PR01183 Ribonucleotide reductase large chain signature 617 644 1.5E-48 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 PRINTS PR01183 Ribonucleotide reductase large chain signature 485 508 1.5E-48 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 PRINTS PR01183 Ribonucleotide reductase large chain signature 442 453 1.5E-48 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS26405 95f2875096d4ad9a92440f665e86b0fe 806 PRINTS PR01183 Ribonucleotide reductase large chain signature 523 545 1.5E-48 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 Gene3D G3DSA:1.10.1670.10 444 492 4.1E-9 T 23-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 Gene3D G3DSA:1.10.10.60 97 153 1.1E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 152 194 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 Gene3D G3DSA:1.10.10.60 154 200 6.0E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 PANTHER PTHR10242:SF3 275 504 6.6E-51 T 23-04-2016 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 PANTHER PTHR10242:SF3 69 256 6.6E-51 T 23-04-2016 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 Pfam PF06029 AlkA N-terminal domain 213 328 1.5E-33 T 23-04-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 PANTHER PTHR10242 275 504 6.6E-51 T 23-04-2016 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 PANTHER PTHR10242 69 256 6.6E-51 T 23-04-2016 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 SUPERFAMILY SSF55945 213 308 8.47E-25 T 23-04-2016 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 SUPERFAMILY SSF48150 319 492 1.73E-15 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 SMART SM00342 115 198 3.7E-20 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 SUPERFAMILY SSF57884 16 98 8.24E-30 T 23-04-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 Gene3D G3DSA:1.10.340.30 331 442 1.1E-7 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 SMART SM01009 213 328 3.0E-49 T 23-04-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 Pfam PF12833 Helix-turn-helix domain 121 198 9.3E-18 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 Pfam PF02805 Metal binding domain of Ada 24 86 9.4E-27 T 23-04-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 Gene3D G3DSA:3.30.310.20 213 327 2.1E-35 T 23-04-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 Gene3D G3DSA:3.40.10.10 19 96 5.3E-31 T 23-04-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 DC74_RS39750 70bfa82964459bab73ecce8f3c481637 514 SUPERFAMILY SSF46689 152 199 1.25E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS35365 45aa076f693f6943d07b67692ec1a5e7 235 Pfam PF07729 FCD domain 86 200 3.1E-18 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS35365 45aa076f693f6943d07b67692ec1a5e7 235 SUPERFAMILY SSF48008 81 203 1.78E-16 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS35365 45aa076f693f6943d07b67692ec1a5e7 235 PANTHER PTHR11751:SF362 12 100 2.4E-15 T 23-04-2016 DC74_RS35365 45aa076f693f6943d07b67692ec1a5e7 235 SMART SM00895 84 207 8.8E-7 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS35365 45aa076f693f6943d07b67692ec1a5e7 235 Gene3D G3DSA:1.20.120.530 80 200 1.8E-17 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS35365 45aa076f693f6943d07b67692ec1a5e7 235 SMART SM00345 16 74 1.0E-15 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS35365 45aa076f693f6943d07b67692ec1a5e7 235 SUPERFAMILY SSF46785 6 77 5.31E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35365 45aa076f693f6943d07b67692ec1a5e7 235 Gene3D G3DSA:1.10.10.10 4 76 1.5E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35365 45aa076f693f6943d07b67692ec1a5e7 235 PANTHER PTHR11751 12 100 2.4E-15 T 23-04-2016 DC74_RS35365 45aa076f693f6943d07b67692ec1a5e7 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 5.8E-17 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS13215 576a915174a7e197518a263d353a74fc 231 SUPERFAMILY SSF46689 6 79 3.33E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS13215 576a915174a7e197518a263d353a74fc 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.0E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13215 576a915174a7e197518a263d353a74fc 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.0E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13215 576a915174a7e197518a263d353a74fc 231 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS13215 576a915174a7e197518a263d353a74fc 231 Gene3D G3DSA:1.10.357.10 3 190 9.7E-36 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS13215 576a915174a7e197518a263d353a74fc 231 PANTHER PTHR30328:SF24 1 226 8.3E-56 T 23-04-2016 DC74_RS13215 576a915174a7e197518a263d353a74fc 231 PANTHER PTHR30328 1 226 8.3E-56 T 23-04-2016 DC74_RS13215 576a915174a7e197518a263d353a74fc 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 2.2E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS20860 0271be6d9e46ef8ab7523efb792c7e66 274 PANTHER PTHR10587 54 265 3.7E-15 T 23-04-2016 DC74_RS20860 0271be6d9e46ef8ab7523efb792c7e66 274 Pfam PF01522 Polysaccharide deacetylase 55 161 1.8E-13 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS20860 0271be6d9e46ef8ab7523efb792c7e66 274 PANTHER PTHR10587:SF72 54 265 3.7E-15 T 23-04-2016 DC74_RS20860 0271be6d9e46ef8ab7523efb792c7e66 274 SUPERFAMILY SSF88713 4 269 1.69E-44 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS20860 0271be6d9e46ef8ab7523efb792c7e66 274 Gene3D G3DSA:3.20.20.370 4 269 1.4E-52 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS33950 c81f381b3a347b3e43ea17b1dc4dba58 203 SUPERFAMILY SSF53335 12 195 5.52E-32 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS33950 c81f381b3a347b3e43ea17b1dc4dba58 203 PANTHER PTHR10108 38 146 1.7E-21 T 23-04-2016 DC74_RS33950 c81f381b3a347b3e43ea17b1dc4dba58 203 Pfam PF08241 Methyltransferase domain 50 145 1.3E-19 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS33950 c81f381b3a347b3e43ea17b1dc4dba58 203 Gene3D G3DSA:3.40.50.150 12 195 4.0E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS26245 db824505ec42c880d8c14446d7ec7b97 489 Pfam PF10103 Zinicin-like metallopeptidase 87 439 4.5E-129 T 23-04-2016 IPR018766 Zinicin-like metallopeptidase type 2 DC74_RS26245 db824505ec42c880d8c14446d7ec7b97 489 SUPERFAMILY SSF55486 86 440 5.64E-119 T 23-04-2016 DC74_RS26245 db824505ec42c880d8c14446d7ec7b97 489 PANTHER PTHR39420:SF2 8 477 1.4E-266 T 23-04-2016 DC74_RS26245 db824505ec42c880d8c14446d7ec7b97 489 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 87 440 6.5E-123 T 23-04-2016 IPR018766 Zinicin-like metallopeptidase type 2 DC74_RS26245 db824505ec42c880d8c14446d7ec7b97 489 PANTHER PTHR39420 8 477 1.4E-266 T 23-04-2016 DC74_RS28205 42e4d29d9acb08499eb7c35c82260090 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 2.0E-62 T 23-04-2016 IPR002661 Ribosome recycling factor GO:0006412 DC74_RS28205 42e4d29d9acb08499eb7c35c82260090 185 Gene3D G3DSA:1.10.132.20 66 185 8.0E-40 T 23-04-2016 IPR023584 Ribosome recycling factor domain DC74_RS28205 42e4d29d9acb08499eb7c35c82260090 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.983 T 23-04-2016 IPR002661 Ribosome recycling factor GO:0006412 DC74_RS28205 42e4d29d9acb08499eb7c35c82260090 185 PANTHER PTHR20982 1 185 2.1E-73 T 23-04-2016 IPR002661 Ribosome recycling factor GO:0006412 DC74_RS28205 42e4d29d9acb08499eb7c35c82260090 185 SUPERFAMILY SSF55194 3 184 9.55E-67 T 23-04-2016 IPR023584 Ribosome recycling factor domain DC74_RS28205 42e4d29d9acb08499eb7c35c82260090 185 Pfam PF01765 Ribosome recycling factor 21 183 2.6E-58 T 23-04-2016 IPR023584 Ribosome recycling factor domain DC74_RS09685 936309f817de138884520173dde61254 659 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 655 32.913 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS09685 936309f817de138884520173dde61254 659 PANTHER PTHR11451 32 656 1.8E-263 T 23-04-2016 DC74_RS09685 936309f817de138884520173dde61254 659 Gene3D G3DSA:3.30.930.10 259 551 2.5E-104 T 23-04-2016 DC74_RS09685 936309f817de138884520173dde61254 659 SUPERFAMILY SSF52954 550 654 5.89E-25 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS09685 936309f817de138884520173dde61254 659 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 343 550 2.6E-36 T 23-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS09685 936309f817de138884520173dde61254 659 Pfam PF03129 Anticodon binding domain 562 649 1.5E-14 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS09685 936309f817de138884520173dde61254 659 SUPERFAMILY SSF55681 260 547 5.55E-92 T 23-04-2016 DC74_RS09685 936309f817de138884520173dde61254 659 Gene3D G3DSA:3.30.980.10 205 241 8.3E-42 T 23-04-2016 DC74_RS09685 936309f817de138884520173dde61254 659 Gene3D G3DSA:3.30.980.10 66 129 8.3E-42 T 23-04-2016 DC74_RS09685 936309f817de138884520173dde61254 659 Gene3D G3DSA:3.30.54.20 131 204 7.7E-12 T 23-04-2016 DC74_RS09685 936309f817de138884520173dde61254 659 SUPERFAMILY SSF55186 64 258 2.09E-53 T 23-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 DC74_RS09685 936309f817de138884520173dde61254 659 SMART SM00863 180 236 2.1E-19 T 23-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 DC74_RS09685 936309f817de138884520173dde61254 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 485 513 7.1E-52 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS09685 936309f817de138884520173dde61254 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 555 567 7.1E-52 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS09685 936309f817de138884520173dde61254 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 349 377 7.1E-52 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS09685 936309f817de138884520173dde61254 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 382 405 7.1E-52 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS09685 936309f817de138884520173dde61254 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 528 541 7.1E-52 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS09685 936309f817de138884520173dde61254 659 PANTHER PTHR11451:SF5 32 656 1.8E-263 T 23-04-2016 DC74_RS09685 936309f817de138884520173dde61254 659 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 190 236 1.7E-12 T 23-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 DC74_RS09685 936309f817de138884520173dde61254 659 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 649 1.5E-190 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS09685 936309f817de138884520173dde61254 659 Gene3D G3DSA:3.40.50.800 552 656 8.3E-27 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS02145 ace5d356d6ab2b1be481efd3e4cc8b2d 335 Gene3D G3DSA:3.60.130.10 32 166 7.8E-61 T 23-04-2016 DC74_RS02145 ace5d356d6ab2b1be481efd3e4cc8b2d 335 Gene3D G3DSA:3.60.130.10 198 322 7.8E-61 T 23-04-2016 DC74_RS02145 ace5d356d6ab2b1be481efd3e4cc8b2d 335 PANTHER PTHR10696:SF27 34 319 6.6E-49 T 23-04-2016 DC74_RS02145 ace5d356d6ab2b1be481efd3e4cc8b2d 335 PANTHER PTHR10696 34 319 6.6E-49 T 23-04-2016 DC74_RS02145 ace5d356d6ab2b1be481efd3e4cc8b2d 335 SUPERFAMILY SSF51197 31 318 1.19E-71 T 23-04-2016 DC74_RS02145 ace5d356d6ab2b1be481efd3e4cc8b2d 335 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 37 316 4.0E-42 T 23-04-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 438 832 1.0E-114 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 SUPERFAMILY SSF52777 206 390 1.62E-7 T 23-04-2016 DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 Pfam PF00501 AMP-binding enzyme 417 808 4.2E-77 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 Gene3D G3DSA:3.30.300.30 803 922 1.2E-34 T 23-04-2016 DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 Pfam PF13193 AMP-binding enzyme C-terminal domain 820 893 8.3E-12 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 SUPERFAMILY SSF56801 399 931 3.4E-131 T 23-04-2016 DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 ProSitePatterns PS00012 Phosphopantetheine attachment site. 945 960 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 Gene3D G3DSA:3.40.50.980 410 563 1.9E-43 T 23-04-2016 DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 Gene3D G3DSA:3.40.50.980 564 721 1.2E-27 T 23-04-2016 DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 PANTHER PTHR24095:SF137 405 964 4.5E-148 T 23-04-2016 DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 PANTHER PTHR24095 405 964 4.5E-148 T 23-04-2016 DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 Gene3D G3DSA:1.10.1200.10 923 995 2.9E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 ProSitePatterns PS00455 Putative AMP-binding domain signature. 557 568 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 SUPERFAMILY SSF47336 915 963 2.52E-7 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 Pfam PF00550 Phosphopantetheine attachment site 921 964 2.3E-7 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS36895 0b371e6ddc1fa4fd7752f4acd3b3a273 999 Gene3D G3DSA:2.30.38.10 722 797 9.6E-22 T 23-04-2016 DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 SUPERFAMILY SSF46785 13 62 1.02E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 Pfam PF13404 AsnC-type helix-turn-helix domain 13 53 5.8E-10 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 Pfam PF13404 AsnC-type helix-turn-helix domain 182 222 2.4E-10 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 59 6.4E-7 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 13 29 6.4E-7 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 40 6.4E-7 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 SUPERFAMILY SSF54909 74 151 3.22E-9 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 SUPERFAMILY SSF46785 182 240 1.63E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 Gene3D G3DSA:1.10.10.10 181 227 2.9E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 Pfam PF01037 Lrp/AsnC ligand binding domain 80 148 7.6E-9 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 SMART SM00344 182 285 9.1E-6 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 SMART SM00344 13 118 5.6E-10 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 Gene3D G3DSA:1.10.10.10 13 60 3.3E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 SUPERFAMILY SSF54909 241 323 1.88E-7 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 Gene3D G3DSA:3.30.70.920 236 324 1.4E-6 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 Gene3D G3DSA:3.30.70.920 79 148 5.1E-12 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS21860 2af472ff0e28eed4d37893e9742e1d17 336 PANTHER PTHR30154 5 173 4.7E-23 T 23-04-2016 DC74_RS05530 f62479d9d997186d7f7090882a014c3e 452 PANTHER PTHR11986:SF83 1 23 2.2E-275 T 23-04-2016 DC74_RS05530 f62479d9d997186d7f7090882a014c3e 452 PANTHER PTHR11986:SF83 39 431 2.2E-275 T 23-04-2016 DC74_RS05530 f62479d9d997186d7f7090882a014c3e 452 PANTHER PTHR11986 39 431 2.2E-275 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS05530 f62479d9d997186d7f7090882a014c3e 452 SUPERFAMILY SSF53383 6 423 2.27E-80 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS05530 f62479d9d997186d7f7090882a014c3e 452 Pfam PF00202 Aminotransferase class-III 40 356 5.2E-37 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS05530 f62479d9d997186d7f7090882a014c3e 452 Gene3D G3DSA:3.90.1150.10 330 424 2.2E-21 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS05530 f62479d9d997186d7f7090882a014c3e 452 Gene3D G3DSA:3.90.1150.10 6 74 2.2E-21 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS05530 f62479d9d997186d7f7090882a014c3e 452 PANTHER PTHR11986 1 23 2.2E-275 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS05530 f62479d9d997186d7f7090882a014c3e 452 Gene3D G3DSA:3.40.640.10 75 328 1.2E-45 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS07605 a47af1d0ffd6509b31540a599461d715 634 Gene3D G3DSA:3.40.50.300 373 621 1.7E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07605 a47af1d0ffd6509b31540a599461d715 634 Gene3D G3DSA:1.20.1560.10 44 337 2.6E-8 T 23-04-2016 DC74_RS07605 a47af1d0ffd6509b31540a599461d715 634 PANTHER PTHR24221 360 624 2.0E-76 T 23-04-2016 DC74_RS07605 a47af1d0ffd6509b31540a599461d715 634 SUPERFAMILY SSF90123 42 336 1.96E-15 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS07605 a47af1d0ffd6509b31540a599461d715 634 SUPERFAMILY SSF52540 364 615 1.41E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07605 a47af1d0ffd6509b31540a599461d715 634 Pfam PF00005 ABC transporter 389 543 8.6E-25 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS07605 a47af1d0ffd6509b31540a599461d715 634 SMART SM00382 398 596 2.1E-19 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS28755 0ec6ba5eb5bd81899936e0b6a4542012 125 SMART SM00418 28 106 6.9E-18 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS28755 0ec6ba5eb5bd81899936e0b6a4542012 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 30 45 6.4E-10 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS28755 0ec6ba5eb5bd81899936e0b6a4542012 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 6.4E-10 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS28755 0ec6ba5eb5bd81899936e0b6a4542012 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 77 92 6.4E-10 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS28755 0ec6ba5eb5bd81899936e0b6a4542012 125 SUPERFAMILY SSF46785 18 104 1.71E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28755 0ec6ba5eb5bd81899936e0b6a4542012 125 Gene3D G3DSA:1.10.10.10 18 104 8.7E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28755 0ec6ba5eb5bd81899936e0b6a4542012 125 PANTHER PTHR33154 14 118 1.7E-22 T 23-04-2016 DC74_RS28755 0ec6ba5eb5bd81899936e0b6a4542012 125 Pfam PF01022 Bacterial regulatory protein, arsR family 36 81 2.5E-10 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS09125 ce4a397b7fba93868ab4779e2421279b 544 SUPERFAMILY SSF52518 1 175 2.65E-34 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS09125 ce4a397b7fba93868ab4779e2421279b 544 Gene3D G3DSA:3.40.50.970 360 538 3.2E-37 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS09125 ce4a397b7fba93868ab4779e2421279b 544 SUPERFAMILY SSF52467 154 341 7.71E-24 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS09125 ce4a397b7fba93868ab4779e2421279b 544 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 170 1.1E-36 T 23-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DC74_RS09125 ce4a397b7fba93868ab4779e2421279b 544 PANTHER PTHR18968 1 523 9.6E-78 T 23-04-2016 DC74_RS09125 ce4a397b7fba93868ab4779e2421279b 544 Gene3D G3DSA:3.40.50.1220 194 337 6.9E-25 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS09125 ce4a397b7fba93868ab4779e2421279b 544 Gene3D G3DSA:3.40.50.970 2 173 1.3E-37 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS09125 ce4a397b7fba93868ab4779e2421279b 544 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 308 1.3E-19 T 23-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DC74_RS09125 ce4a397b7fba93868ab4779e2421279b 544 SUPERFAMILY SSF52518 360 538 9.47E-39 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS09125 ce4a397b7fba93868ab4779e2421279b 544 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 523 6.7E-25 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS09125 ce4a397b7fba93868ab4779e2421279b 544 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 415 434 - T 23-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 DC74_RS36125 d75d59269fa454c60f9d14513aa455bf 234 Gene3D G3DSA:3.30.70.1210 96 232 1.7E-34 T 23-04-2016 DC74_RS36125 d75d59269fa454c60f9d14513aa455bf 234 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 1 232 8.9E-18 T 23-04-2016 IPR010179 CRISPR-associated protein Cse3 DC74_RS36125 d75d59269fa454c60f9d14513aa455bf 234 Pfam PF08798 CRISPR associated protein 1 232 6.2E-65 T 23-04-2016 IPR010179 CRISPR-associated protein Cse3 DC74_RS36125 d75d59269fa454c60f9d14513aa455bf 234 SMART SM01101 1 232 7.4E-73 T 23-04-2016 IPR010179 CRISPR-associated protein Cse3 DC74_RS36125 d75d59269fa454c60f9d14513aa455bf 234 SUPERFAMILY SSF117987 1 85 2.88E-22 T 23-04-2016 DC74_RS36125 d75d59269fa454c60f9d14513aa455bf 234 SUPERFAMILY SSF117987 96 232 1.33E-29 T 23-04-2016 DC74_RS36125 d75d59269fa454c60f9d14513aa455bf 234 Gene3D G3DSA:3.30.70.1200 1 83 1.4E-23 T 23-04-2016 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 SUPERFAMILY SSF48264 9 407 1.15E-94 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 Pfam PF00067 Cytochrome P450 204 367 6.7E-18 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PANTHER PTHR11712 5 410 7.8E-101 T 23-04-2016 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 339 348 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 Gene3D G3DSA:1.10.630.10 7 409 7.5E-128 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00359 B-class P450 signature 152 167 7.7E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00359 B-class P450 signature 188 210 7.7E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00359 B-class P450 signature 315 330 7.7E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00359 B-class P450 signature 84 95 7.7E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00359 B-class P450 signature 346 357 7.7E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00359 B-class P450 signature 269 280 7.7E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00359 B-class P450 signature 135 151 7.7E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00359 B-class P450 signature 287 314 7.7E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00359 B-class P450 signature 337 346 7.7E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00385 P450 superfamily signature 269 280 5.0E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00385 P450 superfamily signature 346 357 5.0E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00385 P450 superfamily signature 234 251 5.0E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35795 6ef3a81445fcc1e6b62aa694bdd6a958 418 PRINTS PR00385 P450 superfamily signature 337 346 5.0E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS28445 92e5b799f1c43485ff0e4b7d2a1e521d 151 Gene3D G3DSA:3.30.300.20 3 118 8.4E-35 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta DC74_RS28445 92e5b799f1c43485ff0e4b7d2a1e521d 151 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 97 3.0E-39 T 23-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 DC74_RS28445 92e5b799f1c43485ff0e4b7d2a1e521d 151 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 111 5.1E-21 T 23-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 DC74_RS28445 92e5b799f1c43485ff0e4b7d2a1e521d 151 PANTHER PTHR33515 2 151 6.4E-45 T 23-04-2016 DC74_RS28445 92e5b799f1c43485ff0e4b7d2a1e521d 151 SUPERFAMILY SSF89919 2 113 1.18E-29 T 23-04-2016 IPR023799 Ribosome-binding factor A domain DC74_RS28445 92e5b799f1c43485ff0e4b7d2a1e521d 151 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 117 19.351 T 23-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 DC74_RS28445 92e5b799f1c43485ff0e4b7d2a1e521d 151 Pfam PF02033 Ribosome-binding factor A 6 110 1.4E-24 T 23-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 TIGRFAM TIGR00498 lexA: repressor LexA 58 265 2.0E-75 T 23-04-2016 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 Gene3D G3DSA:1.10.10.10 59 124 2.2E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 Gene3D G3DSA:2.10.109.10 146 264 7.5E-45 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 PANTHER PTHR33516:SF2 56 265 3.3E-92 T 23-04-2016 DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 220 232 2.6E-11 T 23-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 181 191 2.6E-11 T 23-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 192 203 2.6E-11 T 23-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 PANTHER PTHR33516 56 265 3.3E-92 T 23-04-2016 DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 SUPERFAMILY SSF46785 59 124 4.02E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 SUPERFAMILY SSF51306 145 263 2.27E-36 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 Pfam PF00717 Peptidase S24-like 184 248 1.5E-16 T 23-04-2016 IPR019759 Peptidase S24/S26A/S26B DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 Hamap MF_00015 LexA repressor [lexA]. 59 265 34.212 T 23-04-2016 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 DC74_RS28925 c06e3752a41ea8e8261b2781fa20b6e4 265 Pfam PF01726 LexA DNA binding domain 58 121 1.1E-29 T 23-04-2016 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 DC74_RS21260 87924224100d1c54b54d0f7f2d474f42 553 PANTHER PTHR11632:SF38 471 552 1.3E-267 T 23-04-2016 DC74_RS21260 87924224100d1c54b54d0f7f2d474f42 553 PANTHER PTHR11632:SF38 3 398 1.3E-267 T 23-04-2016 DC74_RS21260 87924224100d1c54b54d0f7f2d474f42 553 Pfam PF00890 FAD binding domain 6 534 9.2E-111 T 23-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain DC74_RS21260 87924224100d1c54b54d0f7f2d474f42 553 Gene3D G3DSA:3.50.50.60 486 550 9.9E-68 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS21260 87924224100d1c54b54d0f7f2d474f42 553 Gene3D G3DSA:3.50.50.60 3 276 9.9E-68 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS21260 87924224100d1c54b54d0f7f2d474f42 553 SUPERFAMILY SSF51905 489 550 4.49E-35 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS21260 87924224100d1c54b54d0f7f2d474f42 553 SUPERFAMILY SSF51905 2 297 4.49E-35 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS21260 87924224100d1c54b54d0f7f2d474f42 553 PANTHER PTHR11632 471 552 1.3E-267 T 23-04-2016 DC74_RS21260 87924224100d1c54b54d0f7f2d474f42 553 PANTHER PTHR11632 3 398 1.3E-267 T 23-04-2016 DC74_RS21260 87924224100d1c54b54d0f7f2d474f42 553 PIRSF PIRSF036654 1 552 1.1E-284 T 23-04-2016 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 KEGG: 00071+1.3.99.-|KEGG: 00280+1.3.99.-|KEGG: 00281+1.3.99.-|KEGG: 00362+1.3.99.-|KEGG: 00626+1.3.99.-|KEGG: 00930+1.3.99.-|UniPathway: UPA00062 DC74_RS16370 237aa1167fda732a091597431d0f6325 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 286 7.1E-70 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS16370 237aa1167fda732a091597431d0f6325 316 PANTHER PTHR10314:SF100 1 307 1.3E-177 T 23-04-2016 DC74_RS16370 237aa1167fda732a091597431d0f6325 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 23-04-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 DC74_RS16370 237aa1167fda732a091597431d0f6325 316 Gene3D G3DSA:3.40.50.1100 42 143 1.3E-38 T 23-04-2016 DC74_RS16370 237aa1167fda732a091597431d0f6325 316 Gene3D G3DSA:3.40.50.1100 149 301 2.7E-68 T 23-04-2016 DC74_RS16370 237aa1167fda732a091597431d0f6325 316 Gene3D G3DSA:3.40.50.1100 3 41 2.7E-68 T 23-04-2016 DC74_RS16370 237aa1167fda732a091597431d0f6325 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 298 3.3E-112 T 23-04-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 DC74_RS16370 237aa1167fda732a091597431d0f6325 316 PANTHER PTHR10314 1 307 1.3E-177 T 23-04-2016 DC74_RS16370 237aa1167fda732a091597431d0f6325 316 SUPERFAMILY SSF53686 6 295 7.99E-89 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS07035 d58f3262e133577295393f1196e3c995 396 Pfam PF00067 Cytochrome P450 177 369 2.7E-22 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00359 B-class P450 signature 271 282 3.6E-62 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00359 B-class P450 signature 152 167 3.6E-62 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00359 B-class P450 signature 290 317 3.6E-62 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00359 B-class P450 signature 135 151 3.6E-62 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00359 B-class P450 signature 88 99 3.6E-62 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00359 B-class P450 signature 190 212 3.6E-62 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00359 B-class P450 signature 318 333 3.6E-62 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00359 B-class P450 signature 339 348 3.6E-62 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00359 B-class P450 signature 348 359 3.6E-62 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 SUPERFAMILY SSF48264 18 396 4.98E-98 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 Gene3D G3DSA:1.10.630.10 11 396 2.9E-128 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00385 P450 superfamily signature 236 253 1.3E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00385 P450 superfamily signature 348 359 1.3E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00385 P450 superfamily signature 339 348 1.3E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PRINTS PR00385 P450 superfamily signature 271 282 1.3E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS07035 d58f3262e133577295393f1196e3c995 396 PANTHER PTHR11712 45 396 1.1E-95 T 23-04-2016 DC74_RS33255 27e6e839e0537cf1a9a0157cbe76be3b 266 PANTHER PTHR30383 10 265 2.7E-115 T 23-04-2016 DC74_RS33255 27e6e839e0537cf1a9a0157cbe76be3b 266 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 21 194 1.8E-27 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS33255 27e6e839e0537cf1a9a0157cbe76be3b 266 Gene3D G3DSA:3.40.50.1110 19 204 2.9E-37 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS33255 27e6e839e0537cf1a9a0157cbe76be3b 266 SUPERFAMILY SSF52266 19 202 1.16E-34 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS33255 27e6e839e0537cf1a9a0157cbe76be3b 266 PANTHER PTHR30383:SF8 10 265 2.7E-115 T 23-04-2016 DC74_RS04300 36bad461a241a9fd31faacee003844fb 81 Pfam PF00486 Transcriptional regulatory protein, C terminal 2 67 3.2E-20 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS04300 36bad461a241a9fd31faacee003844fb 81 PANTHER PTHR26402:SF531 1 68 4.8E-17 T 23-04-2016 DC74_RS04300 36bad461a241a9fd31faacee003844fb 81 SMART SM00862 1 67 1.5E-13 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS04300 36bad461a241a9fd31faacee003844fb 81 PANTHER PTHR26402 1 68 4.8E-17 T 23-04-2016 DC74_RS04300 36bad461a241a9fd31faacee003844fb 81 SUPERFAMILY SSF46894 2 68 2.17E-18 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS04300 36bad461a241a9fd31faacee003844fb 81 Gene3D G3DSA:1.10.10.10 2 70 9.0E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36075 42c98d9069ad10792d58d9aa37aaf9bd 512 Gene3D G3DSA:1.25.40.10 365 479 1.5E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS36075 42c98d9069ad10792d58d9aa37aaf9bd 512 Gene3D G3DSA:1.25.40.10 219 252 1.5E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS37155 da468011137fd12e354d7359a162fdda 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 57 1.3E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37155 da468011137fd12e354d7359a162fdda 200 Gene3D G3DSA:1.10.357.10 1 199 3.7E-41 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS37155 da468011137fd12e354d7359a162fdda 200 Pfam PF13977 Bacterial transcriptional repressor 92 199 9.7E-14 T 23-04-2016 DC74_RS37155 da468011137fd12e354d7359a162fdda 200 PANTHER PTHR30055 2 190 2.2E-19 T 23-04-2016 DC74_RS37155 da468011137fd12e354d7359a162fdda 200 SUPERFAMILY SSF48498 88 198 6.07E-13 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS37155 da468011137fd12e354d7359a162fdda 200 SUPERFAMILY SSF46689 1 74 6.16E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS10850 81e6b4e2946a47195de5428f7c7ac9ed 146 SUPERFAMILY SSF55399 39 146 3.53E-37 T 23-04-2016 IPR023549 Subtilisin inhibitor GO:0004867 DC74_RS10850 81e6b4e2946a47195de5428f7c7ac9ed 146 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 67 85 - T 23-04-2016 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 DC74_RS10850 81e6b4e2946a47195de5428f7c7ac9ed 146 Gene3D G3DSA:3.30.350.10 40 146 1.1E-34 T 23-04-2016 IPR023549 Subtilisin inhibitor GO:0004867 DC74_RS10850 81e6b4e2946a47195de5428f7c7ac9ed 146 Pfam PF00720 Subtilisin inhibitor-like 40 132 4.4E-33 T 23-04-2016 IPR023549 Subtilisin inhibitor GO:0004867 DC74_RS10850 81e6b4e2946a47195de5428f7c7ac9ed 146 Hamap MF_00778 Probable subtilase-type protease inhibitor [sti]. 39 146 30.322 T 23-04-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 DC74_RS10850 81e6b4e2946a47195de5428f7c7ac9ed 146 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 44 136 3.0E-26 T 23-04-2016 IPR023549 Subtilisin inhibitor GO:0004867 DC74_RS10850 81e6b4e2946a47195de5428f7c7ac9ed 146 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 104 120 4.7E-25 T 23-04-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 DC74_RS10850 81e6b4e2946a47195de5428f7c7ac9ed 146 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 41 67 4.7E-25 T 23-04-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 DC74_RS10850 81e6b4e2946a47195de5428f7c7ac9ed 146 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 121 137 4.7E-25 T 23-04-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 DC74_RS09095 55487c31b5c1dc2327ea1207d373b294 184 Pfam PF13419 Haloacid dehalogenase-like hydrolase 52 158 1.7E-16 T 23-04-2016 IPR023214 HAD-like domain DC74_RS09095 55487c31b5c1dc2327ea1207d373b294 184 PANTHER PTHR12725 58 162 7.6E-32 T 23-04-2016 DC74_RS09095 55487c31b5c1dc2327ea1207d373b294 184 SUPERFAMILY SSF56784 4 182 1.8E-35 T 23-04-2016 IPR023214 HAD-like domain DC74_RS09095 55487c31b5c1dc2327ea1207d373b294 184 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 71 153 7.7E-14 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS09095 55487c31b5c1dc2327ea1207d373b294 184 Gene3D G3DSA:3.40.50.1000 46 182 4.9E-36 T 23-04-2016 IPR023214 HAD-like domain DC74_RS09095 55487c31b5c1dc2327ea1207d373b294 184 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 71 84 5.4E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS09095 55487c31b5c1dc2327ea1207d373b294 184 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 148 161 5.4E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS09095 55487c31b5c1dc2327ea1207d373b294 184 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 118 5.4E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS25945 6eeb7b387bbea348dc1e13a42d968331 250 Pfam PF03641 Possible lysine decarboxylase 114 242 3.8E-33 T 23-04-2016 IPR031100 LOG family DC74_RS25945 6eeb7b387bbea348dc1e13a42d968331 250 PANTHER PTHR31223:SF1 31 246 6.1E-92 T 23-04-2016 DC74_RS25945 6eeb7b387bbea348dc1e13a42d968331 250 Gene3D G3DSA:3.40.50.450 51 246 4.8E-63 T 23-04-2016 DC74_RS25945 6eeb7b387bbea348dc1e13a42d968331 250 SUPERFAMILY SSF102405 42 243 3.66E-62 T 23-04-2016 DC74_RS25945 6eeb7b387bbea348dc1e13a42d968331 250 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 72 245 2.3E-42 T 23-04-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG DC74_RS25945 6eeb7b387bbea348dc1e13a42d968331 250 PANTHER PTHR31223 31 246 6.1E-92 T 23-04-2016 DC74_RS04105 5f73e2163af3391c6118b592014fa983 235 Gene3D G3DSA:1.20.120.450 3 121 8.3E-7 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS04105 5f73e2163af3391c6118b592014fa983 235 SUPERFAMILY SSF55718 156 234 3.41E-9 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS04105 5f73e2163af3391c6118b592014fa983 235 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 147 1.1E-20 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS04105 5f73e2163af3391c6118b592014fa983 235 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 214 1.2E-29 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS04105 5f73e2163af3391c6118b592014fa983 235 SUPERFAMILY SSF109854 6 152 2.41E-33 T 23-04-2016 DC74_RS07875 b4cbbfa8dab90cb578f5d08d3ccc9a9d 146 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 34 111 3.6E-13 T 23-04-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 DC74_RS07875 b4cbbfa8dab90cb578f5d08d3ccc9a9d 146 Pfam PF04075 Domain of unknown function (DUF385) 31 108 7.3E-8 T 23-04-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 DC74_RS08790 24dc2a3e70e0babefe4b11f1740cc0f8 105 Pfam PF09851 Short C-terminal domain 67 92 4.6E-7 T 23-04-2016 IPR018649 SHOCT domain DC74_RS24380 e4d32c304f8cfa69d6eecf311020341d 151 PANTHER PTHR23408:SF8 21 127 2.0E-63 T 23-04-2016 DC74_RS24380 e4d32c304f8cfa69d6eecf311020341d 151 SUPERFAMILY SSF52242 18 144 1.96E-48 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS24380 e4d32c304f8cfa69d6eecf311020341d 151 PANTHER PTHR23408 21 127 2.0E-63 T 23-04-2016 DC74_RS24380 e4d32c304f8cfa69d6eecf311020341d 151 Gene3D G3DSA:3.40.50.280 17 146 3.7E-54 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS24380 e4d32c304f8cfa69d6eecf311020341d 151 Pfam PF02310 B12 binding domain 22 135 6.8E-23 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS24380 e4d32c304f8cfa69d6eecf311020341d 151 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 22 147 6.1E-48 T 23-04-2016 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 DC74_RS23595 6dad4ba6994acd932e1b274d97145006 429 SUPERFAMILY SSF103473 3 394 9.81E-60 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS23595 6dad4ba6994acd932e1b274d97145006 429 Pfam PF07690 Major Facilitator Superfamily 21 345 1.3E-43 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS23595 6dad4ba6994acd932e1b274d97145006 429 Gene3D G3DSA:1.20.1250.20 207 394 3.9E-18 T 23-04-2016 DC74_RS23595 6dad4ba6994acd932e1b274d97145006 429 Gene3D G3DSA:1.20.1250.20 17 199 3.6E-29 T 23-04-2016 DC74_RS23595 6dad4ba6994acd932e1b274d97145006 429 PANTHER PTHR23501 12 405 1.7E-143 T 23-04-2016 DC74_RS23595 6dad4ba6994acd932e1b274d97145006 429 PANTHER PTHR23501:SF4 12 405 1.7E-143 T 23-04-2016 DC74_RS30525 3054166332ad25ccc492fde7e5c854cb 251 PANTHER PTHR13370 2 242 9.1E-33 T 23-04-2016 DC74_RS30525 3054166332ad25ccc492fde7e5c854cb 251 Gene3D G3DSA:3.40.50.150 5 240 3.4E-58 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS30525 3054166332ad25ccc492fde7e5c854cb 251 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 215 235 6.1E-22 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 DC74_RS30525 3054166332ad25ccc492fde7e5c854cb 251 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 192 210 6.1E-22 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 DC74_RS30525 3054166332ad25ccc492fde7e5c854cb 251 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 21 35 6.1E-22 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 DC74_RS30525 3054166332ad25ccc492fde7e5c854cb 251 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 174 191 6.1E-22 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 DC74_RS30525 3054166332ad25ccc492fde7e5c854cb 251 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 79 99 6.1E-22 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 DC74_RS30525 3054166332ad25ccc492fde7e5c854cb 251 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 25 31 - T 23-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 DC74_RS30525 3054166332ad25ccc492fde7e5c854cb 251 Pfam PF01555 DNA methylase 22 147 2.3E-12 T 23-04-2016 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 DC74_RS30525 3054166332ad25ccc492fde7e5c854cb 251 Pfam PF01555 DNA methylase 169 231 7.2E-17 T 23-04-2016 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 DC74_RS30525 3054166332ad25ccc492fde7e5c854cb 251 SUPERFAMILY SSF53335 4 235 4.31E-51 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14585 aa32b51e189f9e12037cd563d965c779 478 SUPERFAMILY SSF53067 231 456 7.13E-30 T 23-04-2016 DC74_RS14585 aa32b51e189f9e12037cd563d965c779 478 PIRSF PIRSF000538 1 464 1.2E-57 T 23-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 DC74_RS14585 aa32b51e189f9e12037cd563d965c779 478 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 329 350 - T 23-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 DC74_RS14585 aa32b51e189f9e12037cd563d965c779 478 PANTHER PTHR10196 445 471 5.8E-97 T 23-04-2016 DC74_RS14585 aa32b51e189f9e12037cd563d965c779 478 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 226 1.8E-32 T 23-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 DC74_RS14585 aa32b51e189f9e12037cd563d965c779 478 PANTHER PTHR10196 1 419 5.8E-97 T 23-04-2016 DC74_RS14585 aa32b51e189f9e12037cd563d965c779 478 Gene3D G3DSA:3.30.420.40 232 462 5.0E-20 T 23-04-2016 DC74_RS14585 aa32b51e189f9e12037cd563d965c779 478 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 234 418 1.9E-16 T 23-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 DC74_RS14585 aa32b51e189f9e12037cd563d965c779 478 PANTHER PTHR10196:SF67 445 471 5.8E-97 T 23-04-2016 DC74_RS14585 aa32b51e189f9e12037cd563d965c779 478 SUPERFAMILY SSF53067 1 229 9.71E-32 T 23-04-2016 DC74_RS14585 aa32b51e189f9e12037cd563d965c779 478 Gene3D G3DSA:3.30.420.40 1 226 2.2E-32 T 23-04-2016 DC74_RS14585 aa32b51e189f9e12037cd563d965c779 478 PANTHER PTHR10196:SF67 1 419 5.8E-97 T 23-04-2016 DC74_RS24700 883e8659ee15676190e4e606328ba6b5 299 PANTHER PTHR30213 24 284 1.5E-45 T 23-04-2016 DC74_RS24700 883e8659ee15676190e4e606328ba6b5 299 PIRSF PIRSF035875 14 298 1.6E-23 T 23-04-2016 IPR017039 Virulence factor BrkB DC74_RS24700 883e8659ee15676190e4e606328ba6b5 299 Pfam PF03631 Virulence factor BrkB 37 284 2.3E-45 T 23-04-2016 IPR017039 Virulence factor BrkB DC74_RS24700 883e8659ee15676190e4e606328ba6b5 299 PANTHER PTHR30213:SF1 24 284 1.5E-45 T 23-04-2016 DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 5.3E-6 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 5.3E-6 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 316 5.2E-12 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 SMART SM00387 360 470 2.8E-25 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 Pfam PF00672 HAMP domain 186 249 2.9E-11 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 SMART SM00388 254 317 1.7E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 SUPERFAMILY SSF55874 306 468 1.83E-32 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 Gene3D G3DSA:3.30.565.10 323 469 1.3E-30 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 PANTHER PTHR24423 17 24 5.5E-61 T 23-04-2016 DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 PANTHER PTHR24423 194 471 5.5E-61 T 23-04-2016 DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 SMART SM00304 200 253 2.1E-9 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 Gene3D G3DSA:1.10.287.130 244 312 4.8E-12 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 468 3.1E-18 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 SUPERFAMILY SSF47384 237 315 1.08E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS28830 e7870b5fb05122b7dd5750a5da5c210f 471 SUPERFAMILY SSF158472 201 251 7.98E-6 T 23-04-2016 DC74_RS08115 3c9bba34c0ec96cc68806e84530f712c 238 PANTHER PTHR37313:SF3 1 238 1.2E-114 T 23-04-2016 DC74_RS08115 3c9bba34c0ec96cc68806e84530f712c 238 Pfam PF05949 Bacterial protein of unknown function (DUF881) 101 233 3.5E-40 T 23-04-2016 IPR010273 Protein of unknown function DUF881 DC74_RS08115 3c9bba34c0ec96cc68806e84530f712c 238 PANTHER PTHR37313 1 238 1.2E-114 T 23-04-2016 DC74_RS34900 e4557a7bbf53c433973e0e2137402435 194 SUPERFAMILY SSF55729 11 188 1.44E-32 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS34900 e4557a7bbf53c433973e0e2137402435 194 Pfam PF13302 Acetyltransferase (GNAT) domain 12 164 9.0E-15 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS34900 e4557a7bbf53c433973e0e2137402435 194 PANTHER PTHR13256:SF24 12 185 5.5E-33 T 23-04-2016 DC74_RS34900 e4557a7bbf53c433973e0e2137402435 194 Gene3D G3DSA:3.40.630.30 11 186 3.2E-37 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS34900 e4557a7bbf53c433973e0e2137402435 194 PANTHER PTHR13256 12 185 5.5E-33 T 23-04-2016 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 2.7E-5 T 23-04-2016 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.7E-5 T 23-04-2016 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 SUPERFAMILY SSF50475 418 568 9.81E-50 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 Gene3D G3DSA:3.50.50.60 274 326 7.6E-12 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 Gene3D G3DSA:3.50.50.60 2 167 7.6E-12 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 Pfam PF01613 Flavin reductase like domain 427 569 1.1E-36 T 23-04-2016 IPR002563 Flavin reductase like domain GO:0010181 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 SUPERFAMILY SSF51905 2 159 1.97E-18 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 SUPERFAMILY SSF51905 283 364 1.97E-18 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 Gene3D G3DSA:2.30.110.10 415 568 1.7E-57 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 PANTHER PTHR30466 420 572 2.9E-40 T 23-04-2016 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 PANTHER PTHR30466:SF1 420 572 2.9E-40 T 23-04-2016 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 SMART SM00903 426 569 2.4E-62 T 23-04-2016 IPR002563 Flavin reductase like domain GO:0010181 DC74_RS02110 81688d74a995fbff50663719eaeda2b2 576 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 49 4.0E-6 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS36595 6288dea7f09779ce426315f96759510d 316 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 5 303 1.0E-65 T 23-04-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DC74_RS36595 6288dea7f09779ce426315f96759510d 316 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 9 19 - T 23-04-2016 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 DC74_RS36595 6288dea7f09779ce426315f96759510d 316 PANTHER PTHR12304 4 314 1.1E-91 T 23-04-2016 IPR023186 Inosine/uridine-preferring nucleoside hydrolase DC74_RS36595 6288dea7f09779ce426315f96759510d 316 SUPERFAMILY SSF53590 5 310 1.02E-80 T 23-04-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DC74_RS36595 6288dea7f09779ce426315f96759510d 316 Gene3D G3DSA:3.90.245.10 5 311 7.2E-87 T 23-04-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DC74_RS36120 2dc3fe3d9ec325412c129e5e66e00746 242 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 7 212 1.2E-41 T 23-04-2016 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 DC74_RS36120 2dc3fe3d9ec325412c129e5e66e00746 242 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 8 48 2.5E-9 T 23-04-2016 IPR013422 CRISPR-associated protein Cas5, N-terminal DC74_RS36120 2dc3fe3d9ec325412c129e5e66e00746 242 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 8 211 4.0E-49 T 23-04-2016 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 314 421 1.1E-15 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 SMART SM00387 310 421 3.7E-25 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 Gene3D G3DSA:1.10.287.130 192 264 5.9E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 SUPERFAMILY SSF158472 149 198 1.12E-8 T 23-04-2016 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 Pfam PF00672 HAMP domain 129 197 3.7E-14 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 SMART SM00304 148 201 1.7E-12 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 PANTHER PTHR24423 142 421 5.5E-68 T 23-04-2016 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 PANTHER PTHR24423 31 36 5.5E-68 T 23-04-2016 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 Pfam PF00512 His Kinase A (phospho-acceptor) domain 202 267 4.7E-10 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 401 1.2E-8 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 362 1.2E-8 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 376 1.2E-8 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 420 1.2E-8 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 Gene3D G3DSA:3.30.565.10 271 421 3.8E-35 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 SMART SM00388 202 268 4.5E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 SUPERFAMILY SSF47384 185 267 9.81E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS29145 054b10944ef7e79b2c98edafb24c80ab 421 SUPERFAMILY SSF55874 271 421 1.96E-32 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS34075 da61eac4f2f6ec38806e694a0666292a 256 Gene3D G3DSA:1.10.10.10 20 84 1.6E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34075 da61eac4f2f6ec38806e694a0666292a 256 SMART SM00345 23 82 2.0E-16 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS34075 da61eac4f2f6ec38806e694a0666292a 256 Gene3D G3DSA:3.40.1410.10 112 235 4.2E-4 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS34075 da61eac4f2f6ec38806e694a0666292a 256 SUPERFAMILY SSF46785 20 85 2.35E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34075 da61eac4f2f6ec38806e694a0666292a 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 2.912652E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS34075 da61eac4f2f6ec38806e694a0666292a 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 2.912652E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS34075 da61eac4f2f6ec38806e694a0666292a 256 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 82 5.5E-17 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS34075 da61eac4f2f6ec38806e694a0666292a 256 SUPERFAMILY SSF64288 70 245 1.73E-9 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS34075 da61eac4f2f6ec38806e694a0666292a 256 PANTHER PTHR11751 24 79 3.5E-16 T 23-04-2016 DC74_RS14945 bab1f81eae1df9a271018f6cfeba5c0a 312 PANTHER PTHR11649:SF3 3 312 2.5E-101 T 23-04-2016 DC74_RS14945 bab1f81eae1df9a271018f6cfeba5c0a 312 SUPERFAMILY SSF54814 193 312 6.21E-35 T 23-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 DC74_RS14945 bab1f81eae1df9a271018f6cfeba5c0a 312 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 18 142 7.8E-17 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 DC74_RS14945 bab1f81eae1df9a271018f6cfeba5c0a 312 Gene3D G3DSA:3.30.300.20 203 309 1.2E-36 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta DC74_RS14945 bab1f81eae1df9a271018f6cfeba5c0a 312 Hamap MF_00367 GTPase Era [era]. 11 312 34.511 T 23-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 DC74_RS14945 bab1f81eae1df9a271018f6cfeba5c0a 312 Pfam PF07650 KH domain 219 301 4.9E-17 T 23-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 DC74_RS14945 bab1f81eae1df9a271018f6cfeba5c0a 312 Gene3D G3DSA:3.40.50.300 17 202 3.2E-36 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14945 bab1f81eae1df9a271018f6cfeba5c0a 312 SUPERFAMILY SSF52540 17 224 1.11E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14945 bab1f81eae1df9a271018f6cfeba5c0a 312 Pfam PF01926 50S ribosome-binding GTPase 17 131 1.8E-20 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS14945 bab1f81eae1df9a271018f6cfeba5c0a 312 PANTHER PTHR11649 3 312 2.5E-101 T 23-04-2016 DC74_RS14945 bab1f81eae1df9a271018f6cfeba5c0a 312 TIGRFAM TIGR00436 era: GTP-binding protein Era 14 295 1.5E-65 T 23-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 SUPERFAMILY SSF56553 48 169 4.97E-42 T 23-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 302 5.9E-26 T 23-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 34.296 T 23-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 SUPERFAMILY SSF47789 247 318 1.83E-23 T 23-04-2016 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 Gene3D G3DSA:1.10.150.20 245 319 9.2E-32 T 23-04-2016 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 PANTHER PTHR32108 12 324 1.4E-134 T 23-04-2016 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 Gene3D G3DSA:2.170.120.12 62 168 4.2E-45 T 23-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 257 311 2.0E-24 T 23-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 Gene3D G3DSA:3.30.1360.10 7 61 1.3E-10 T 23-04-2016 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 2.4E-19 T 23-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 PANTHER PTHR32108:SF0 12 324 1.4E-134 T 23-04-2016 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 3.4E-115 T 23-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 SUPERFAMILY SSF55257 14 48 2.35E-24 T 23-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 SUPERFAMILY SSF55257 170 220 2.35E-24 T 23-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 Gene3D G3DSA:3.30.1360.10 171 217 2.3E-4 T 23-04-2016 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 5.8E-24 T 23-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18600 5f6c775f115d63ac3e6deea7297c5af2 340 SMART SM00662 18 225 1.3E-94 T 23-04-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 Gene3D G3DSA:1.10.10.10 156 215 1.4E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 SUPERFAMILY SSF46894 146 215 1.22E-19 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 5.3E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 5.3E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 5.3E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 PANTHER PTHR26402:SF151 2 217 2.6E-77 T 23-04-2016 DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 PANTHER PTHR26402 2 217 2.6E-77 T 23-04-2016 DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 9.7E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 SUPERFAMILY SSF52172 2 132 4.84E-34 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 SMART SM00421 153 210 2.7E-21 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 Pfam PF00072 Response regulator receiver domain 4 115 7.5E-29 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 SMART SM00448 2 115 5.5E-31 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS34600 d6980b96cd1a078592aa07c7690de807 217 Gene3D G3DSA:3.40.50.2300 2 155 9.4E-40 T 23-04-2016 DC74_RS03845 bc355decca293136011feae2740b2c3a 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS03845 bc355decca293136011feae2740b2c3a 247 SUPERFAMILY SSF51735 5 245 8.76E-73 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03845 bc355decca293136011feae2740b2c3a 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 2.2E-57 T 23-04-2016 DC74_RS03845 bc355decca293136011feae2740b2c3a 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 186 0.001 T 23-04-2016 DC74_RS03845 bc355decca293136011feae2740b2c3a 247 Gene3D G3DSA:3.40.50.720 4 244 4.0E-74 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03845 bc355decca293136011feae2740b2c3a 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 5.3E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03845 bc355decca293136011feae2740b2c3a 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 5.3E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03845 bc355decca293136011feae2740b2c3a 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 5.3E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03845 bc355decca293136011feae2740b2c3a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.6E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03845 bc355decca293136011feae2740b2c3a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.6E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03845 bc355decca293136011feae2740b2c3a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.6E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03845 bc355decca293136011feae2740b2c3a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 5.6E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03845 bc355decca293136011feae2740b2c3a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.6E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03845 bc355decca293136011feae2740b2c3a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.6E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03845 bc355decca293136011feae2740b2c3a 247 PANTHER PTHR24322 11 131 4.0E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03845 bc355decca293136011feae2740b2c3a 247 PANTHER PTHR24322 150 182 4.0E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS25330 e5109ae3108489c61e0446019df55c86 198 PANTHER PTHR20855 22 190 4.7E-41 T 23-04-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 DC74_RS25330 e5109ae3108489c61e0446019df55c86 198 PANTHER PTHR20855:SF3 22 190 4.7E-41 T 23-04-2016 IPR005744 Hly-III GO:0016021|GO:0019835 DC74_RS25330 e5109ae3108489c61e0446019df55c86 198 Pfam PF03006 Haemolysin-III related 11 187 9.5E-40 T 23-04-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 DC74_RS13165 e5b4db0518c46c5bdbf632ad9f1008f8 188 SUPERFAMILY SSF144091 2 163 3.66E-6 T 23-04-2016 DC74_RS13165 e5b4db0518c46c5bdbf632ad9f1008f8 188 Gene3D G3DSA:1.20.1540.10 67 154 3.6E-4 T 23-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 DC74_RS13075 7055edae475b0bc9a6914674f7f729ca 310 SUPERFAMILY SSF51735 1 255 4.8E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS13075 7055edae475b0bc9a6914674f7f729ca 310 PANTHER PTHR24322:SF211 46 152 1.4E-60 T 23-04-2016 DC74_RS13075 7055edae475b0bc9a6914674f7f729ca 310 PANTHER PTHR24322:SF211 170 202 1.4E-60 T 23-04-2016 DC74_RS13075 7055edae475b0bc9a6914674f7f729ca 310 PANTHER PTHR24322:SF211 8 27 1.4E-60 T 23-04-2016 DC74_RS13075 7055edae475b0bc9a6914674f7f729ca 310 Pfam PF00106 short chain dehydrogenase 7 205 6.8E-13 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13075 7055edae475b0bc9a6914674f7f729ca 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 1.4E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13075 7055edae475b0bc9a6914674f7f729ca 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.4E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13075 7055edae475b0bc9a6914674f7f729ca 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.4E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13075 7055edae475b0bc9a6914674f7f729ca 310 PANTHER PTHR24322 46 152 1.4E-60 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13075 7055edae475b0bc9a6914674f7f729ca 310 PANTHER PTHR24322 170 202 1.4E-60 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13075 7055edae475b0bc9a6914674f7f729ca 310 PANTHER PTHR24322 8 27 1.4E-60 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13075 7055edae475b0bc9a6914674f7f729ca 310 Gene3D G3DSA:3.40.50.720 1 257 7.8E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16875 ef68d2f5eb12eb7726277597118f9d00 225 PANTHER PTHR26402:SF50 3 224 1.9E-109 T 23-04-2016 DC74_RS16875 ef68d2f5eb12eb7726277597118f9d00 225 Gene3D G3DSA:1.10.10.10 124 222 1.4E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16875 ef68d2f5eb12eb7726277597118f9d00 225 SUPERFAMILY SSF46894 119 221 3.12E-29 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS16875 ef68d2f5eb12eb7726277597118f9d00 225 SUPERFAMILY SSF52172 2 130 5.83E-43 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS16875 ef68d2f5eb12eb7726277597118f9d00 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 3.5E-25 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS16875 ef68d2f5eb12eb7726277597118f9d00 225 SMART SM00862 146 222 5.9E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS16875 ef68d2f5eb12eb7726277597118f9d00 225 Gene3D G3DSA:3.40.50.2300 2 123 2.1E-40 T 23-04-2016 DC74_RS16875 ef68d2f5eb12eb7726277597118f9d00 225 SMART SM00448 3 113 1.1E-44 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS16875 ef68d2f5eb12eb7726277597118f9d00 225 PANTHER PTHR26402 3 224 1.9E-109 T 23-04-2016 DC74_RS16875 ef68d2f5eb12eb7726277597118f9d00 225 Pfam PF00072 Response regulator receiver domain 5 114 1.2E-28 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS02210 f2c664496c7c7b0a265d9c666eeffc03 325 Pfam PF00891 O-methyltransferase 90 306 5.4E-45 T 23-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 DC74_RS02210 f2c664496c7c7b0a265d9c666eeffc03 325 PANTHER PTHR11746:SF63 5 323 4.1E-87 T 23-04-2016 DC74_RS02210 f2c664496c7c7b0a265d9c666eeffc03 325 PIRSF PIRSF005739 1 324 1.1E-53 T 23-04-2016 IPR016461 O-methyltransferase COMT-type GO:0008168 DC74_RS02210 f2c664496c7c7b0a265d9c666eeffc03 325 Gene3D G3DSA:3.40.50.150 85 323 5.3E-66 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS02210 f2c664496c7c7b0a265d9c666eeffc03 325 PANTHER PTHR11746 5 323 4.1E-87 T 23-04-2016 DC74_RS02210 f2c664496c7c7b0a265d9c666eeffc03 325 Gene3D G3DSA:1.10.10.10 2 84 3.1E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02210 f2c664496c7c7b0a265d9c666eeffc03 325 SUPERFAMILY SSF46785 3 80 3.07E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02210 f2c664496c7c7b0a265d9c666eeffc03 325 SUPERFAMILY SSF53335 84 322 1.32E-50 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS18145 7fa6ab6ff871aa082e864f79feb7cd74 340 Gene3D G3DSA:3.40.50.720 135 310 2.0E-58 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18145 7fa6ab6ff871aa082e864f79feb7cd74 340 SUPERFAMILY SSF52283 20 148 1.76E-21 T 23-04-2016 DC74_RS18145 7fa6ab6ff871aa082e864f79feb7cd74 340 PANTHER PTHR10996:SF127 9 338 6.2E-122 T 23-04-2016 DC74_RS18145 7fa6ab6ff871aa082e864f79feb7cd74 340 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 135 309 4.7E-54 T 23-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DC74_RS18145 7fa6ab6ff871aa082e864f79feb7cd74 340 PANTHER PTHR10996 9 338 6.2E-122 T 23-04-2016 DC74_RS18145 7fa6ab6ff871aa082e864f79feb7cd74 340 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 58 338 2.1E-11 T 23-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 DC74_RS18145 7fa6ab6ff871aa082e864f79feb7cd74 340 SUPERFAMILY SSF51735 130 309 1.22E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18145 7fa6ab6ff871aa082e864f79feb7cd74 340 Gene3D G3DSA:3.40.50.720 56 134 1.1E-22 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39365 4582daeedfb985d5fc5ed078ab82a5b1 457 PANTHER PTHR23501:SF7 13 450 2.3E-123 T 23-04-2016 DC74_RS39365 4582daeedfb985d5fc5ed078ab82a5b1 457 PANTHER PTHR23501 13 450 2.3E-123 T 23-04-2016 DC74_RS39365 4582daeedfb985d5fc5ed078ab82a5b1 457 Gene3D G3DSA:1.20.1250.20 247 448 2.3E-22 T 23-04-2016 DC74_RS39365 4582daeedfb985d5fc5ed078ab82a5b1 457 Pfam PF07690 Major Facilitator Superfamily 9 398 2.9E-59 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS39365 4582daeedfb985d5fc5ed078ab82a5b1 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 389 408 2.3E-5 T 23-04-2016 DC74_RS39365 4582daeedfb985d5fc5ed078ab82a5b1 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 96 116 2.3E-5 T 23-04-2016 DC74_RS39365 4582daeedfb985d5fc5ed078ab82a5b1 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 256 281 2.3E-5 T 23-04-2016 DC74_RS39365 4582daeedfb985d5fc5ed078ab82a5b1 457 Gene3D G3DSA:1.20.1250.20 3 187 8.6E-32 T 23-04-2016 DC74_RS39365 4582daeedfb985d5fc5ed078ab82a5b1 457 SUPERFAMILY SSF103473 237 453 5.36E-71 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS39365 4582daeedfb985d5fc5ed078ab82a5b1 457 SUPERFAMILY SSF103473 2 186 5.36E-71 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS27975 a3cccd0707d630a1c907bc657be88011 556 Pfam PF02734 DAK2 domain 35 213 6.0E-27 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 DC74_RS27975 a3cccd0707d630a1c907bc657be88011 556 PANTHER PTHR33434:SF4 1 556 7.9E-164 T 23-04-2016 DC74_RS27975 a3cccd0707d630a1c907bc657be88011 556 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 556 2.0E-128 T 23-04-2016 IPR019986 DAK2 domain-containing protein YloV DC74_RS27975 a3cccd0707d630a1c907bc657be88011 556 SMART SM01121 256 556 7.3E-97 T 23-04-2016 IPR033470 Uncharacterised protein, DhaK domain DC74_RS27975 a3cccd0707d630a1c907bc657be88011 556 SUPERFAMILY SSF101473 5 216 3.4E-31 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 DC74_RS27975 a3cccd0707d630a1c907bc657be88011 556 PANTHER PTHR33434 1 556 7.9E-164 T 23-04-2016 DC74_RS27975 a3cccd0707d630a1c907bc657be88011 556 SMART SM01120 35 214 4.2E-44 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 DC74_RS27975 a3cccd0707d630a1c907bc657be88011 556 Pfam PF13684 Dihydroxyacetone kinase family 258 556 6.7E-77 T 23-04-2016 IPR033470 Uncharacterised protein, DhaK domain DC74_RS22150 b8432b3d953594b85f39d5979c04f48c 756 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 1 742 0.0 T 23-04-2016 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria DC74_RS22150 b8432b3d953594b85f39d5979c04f48c 756 Pfam PF09369 Domain of unknown function (DUF1998) 638 717 4.6E-19 T 23-04-2016 IPR018973 DEAD/DEAH-box helicase, putative DC74_RS22150 b8432b3d953594b85f39d5979c04f48c 756 SUPERFAMILY SSF52540 259 394 7.43E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22150 b8432b3d953594b85f39d5979c04f48c 756 SUPERFAMILY SSF52540 81 222 7.43E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22150 b8432b3d953594b85f39d5979c04f48c 756 Pfam PF00271 Helicase conserved C-terminal domain 267 377 1.4E-10 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS22150 b8432b3d953594b85f39d5979c04f48c 756 PANTHER PTHR24031:SF122 3 416 1.1E-120 T 23-04-2016 DC74_RS22150 b8432b3d953594b85f39d5979c04f48c 756 PANTHER PTHR24031 3 416 1.1E-120 T 23-04-2016 DC74_RS22150 b8432b3d953594b85f39d5979c04f48c 756 SMART SM00487 27 236 7.5E-29 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS22150 b8432b3d953594b85f39d5979c04f48c 756 SMART SM00490 296 377 1.7E-15 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS22150 b8432b3d953594b85f39d5979c04f48c 756 Gene3D G3DSA:3.40.50.300 261 405 9.8E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22150 b8432b3d953594b85f39d5979c04f48c 756 Pfam PF00270 DEAD/DEAH box helicase 34 208 1.2E-24 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS22150 b8432b3d953594b85f39d5979c04f48c 756 Gene3D G3DSA:3.40.50.300 9 213 1.5E-35 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39500 e112ebb933bd87a4c01b9c83e7e4a28f 233 PANTHER PTHR10108 48 161 7.4E-21 T 23-04-2016 DC74_RS39500 e112ebb933bd87a4c01b9c83e7e4a28f 233 Gene3D G3DSA:3.40.50.150 25 190 3.9E-27 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS39500 e112ebb933bd87a4c01b9c83e7e4a28f 233 SUPERFAMILY SSF53335 22 189 5.02E-28 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS39500 e112ebb933bd87a4c01b9c83e7e4a28f 233 Pfam PF13649 Methyltransferase domain 48 142 3.7E-15 T 23-04-2016 DC74_RS39500 e112ebb933bd87a4c01b9c83e7e4a28f 233 PANTHER PTHR10108:SF918 48 161 7.4E-21 T 23-04-2016 DC74_RS06190 7e84dd8d4fc8596042c6b4b9c1116ac1 576 PANTHER PTHR11814 37 569 1.3E-84 T 23-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 DC74_RS06190 7e84dd8d4fc8596042c6b4b9c1116ac1 576 SUPERFAMILY SSF52091 454 556 1.26E-12 T 23-04-2016 IPR002645 STAS domain DC74_RS06190 7e84dd8d4fc8596042c6b4b9c1116ac1 576 Pfam PF00916 Sulfate permease family 38 394 5.3E-55 T 23-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 DC74_RS06190 7e84dd8d4fc8596042c6b4b9c1116ac1 576 Pfam PF01740 STAS domain 456 551 2.1E-9 T 23-04-2016 IPR002645 STAS domain DC74_RS06190 7e84dd8d4fc8596042c6b4b9c1116ac1 576 Gene3D G3DSA:3.30.750.24 454 555 2.9E-11 T 23-04-2016 IPR002645 STAS domain DC74_RS25570 72ee53c3542c19fc4cb291900a72ee3e 240 Gene3D G3DSA:2.40.380.10 28 221 8.7E-74 T 23-04-2016 IPR007295 Domain of unknown function DUF402 DC74_RS25570 72ee53c3542c19fc4cb291900a72ee3e 240 SUPERFAMILY SSF159234 53 223 1.31E-42 T 23-04-2016 DC74_RS25570 72ee53c3542c19fc4cb291900a72ee3e 240 Pfam PF04167 Protein of unknown function (DUF402) 111 175 1.8E-14 T 23-04-2016 IPR007295 Domain of unknown function DUF402 DC74_RS07950 283d0f535df54460b2818bb261885fa4 214 SUPERFAMILY SSF52499 7 207 3.79E-35 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS07950 283d0f535df54460b2818bb261885fa4 214 PANTHER PTHR11080 5 205 2.9E-16 T 23-04-2016 DC74_RS07950 283d0f535df54460b2818bb261885fa4 214 Gene3D G3DSA:3.40.50.850 10 208 1.5E-35 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS07950 283d0f535df54460b2818bb261885fa4 214 Pfam PF00857 Isochorismatase family 16 202 1.3E-23 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS19060 065f47b9429227251e93efd9525592bb 444 SUPERFAMILY SSF56762 52 444 4.32E-123 T 23-04-2016 IPR029014 NiFe hydrogenase-like DC74_RS19060 065f47b9429227251e93efd9525592bb 444 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 79 90 - T 23-04-2016 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 DC74_RS19060 065f47b9429227251e93efd9525592bb 444 PANTHER PTHR11993 29 339 1.3E-227 T 23-04-2016 DC74_RS19060 065f47b9429227251e93efd9525592bb 444 PANTHER PTHR11993 356 439 1.3E-227 T 23-04-2016 DC74_RS19060 065f47b9429227251e93efd9525592bb 444 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 159 444 2.6E-113 T 23-04-2016 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 DC74_RS19060 065f47b9429227251e93efd9525592bb 444 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 42 444 1.5E-174 T 23-04-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 DC74_RS19060 065f47b9429227251e93efd9525592bb 444 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 38 444 47.001 T 23-04-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 DC74_RS19060 065f47b9429227251e93efd9525592bb 444 PANTHER PTHR11993:SF28 29 339 1.3E-227 T 23-04-2016 DC74_RS19060 065f47b9429227251e93efd9525592bb 444 PANTHER PTHR11993:SF28 356 439 1.3E-227 T 23-04-2016 DC74_RS19060 065f47b9429227251e93efd9525592bb 444 Gene3D G3DSA:1.10.645.10 372 437 2.2E-70 T 23-04-2016 IPR029014 NiFe hydrogenase-like DC74_RS19060 065f47b9429227251e93efd9525592bb 444 Gene3D G3DSA:1.10.645.10 35 328 2.2E-70 T 23-04-2016 IPR029014 NiFe hydrogenase-like DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 Pfam PF00106 short chain dehydrogenase 9 212 5.4E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 5.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 5.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 5.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 5.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 5.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 4.3E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 4.3E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 4.3E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PANTHER PTHR24322:SF428 57 158 1.2E-47 T 23-04-2016 DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PANTHER PTHR24322:SF428 174 205 1.2E-47 T 23-04-2016 DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PANTHER PTHR24322:SF428 12 31 1.2E-47 T 23-04-2016 DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 SUPERFAMILY SSF51735 2 263 7.89E-67 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 234 6.3E-4 T 23-04-2016 DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PANTHER PTHR24322 57 158 1.2E-47 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PANTHER PTHR24322 174 205 1.2E-47 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 PANTHER PTHR24322 12 31 1.2E-47 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13565 c3ce676993548a4aad11f5477c24b525 313 Gene3D G3DSA:3.40.50.720 2 262 6.3E-73 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09235 7eed7f136422f18eb5cb675af23dd3b5 258 Pfam PF13460 NAD(P)H-binding 11 143 3.5E-21 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09235 7eed7f136422f18eb5cb675af23dd3b5 258 PANTHER PTHR14194 1 257 3.1E-81 T 23-04-2016 DC74_RS09235 7eed7f136422f18eb5cb675af23dd3b5 258 SUPERFAMILY SSF51735 5 221 2.12E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09235 7eed7f136422f18eb5cb675af23dd3b5 258 Gene3D G3DSA:3.40.50.720 5 214 7.8E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09235 7eed7f136422f18eb5cb675af23dd3b5 258 PANTHER PTHR14194:SF67 1 257 3.1E-81 T 23-04-2016 DC74_RS07415 c277a56475adcc303a33cf6ae2707753 359 Gene3D G3DSA:3.40.50.150 112 357 4.1E-72 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS07415 c277a56475adcc303a33cf6ae2707753 359 PANTHER PTHR11746:SF63 8 358 6.8E-91 T 23-04-2016 DC74_RS07415 c277a56475adcc303a33cf6ae2707753 359 SUPERFAMILY SSF53335 110 355 7.26E-53 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS07415 c277a56475adcc303a33cf6ae2707753 359 Pfam PF00891 O-methyltransferase 118 338 8.9E-49 T 23-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 DC74_RS07415 c277a56475adcc303a33cf6ae2707753 359 PANTHER PTHR11746 8 358 6.8E-91 T 23-04-2016 DC74_RS07415 c277a56475adcc303a33cf6ae2707753 359 PIRSF PIRSF005739 13 356 6.6E-53 T 23-04-2016 IPR016461 O-methyltransferase COMT-type GO:0008168 DC74_RS07415 c277a56475adcc303a33cf6ae2707753 359 Gene3D G3DSA:1.10.10.10 24 111 1.8E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07415 c277a56475adcc303a33cf6ae2707753 359 SUPERFAMILY SSF46785 26 107 5.39E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07415 c277a56475adcc303a33cf6ae2707753 359 Pfam PF16864 Dimerisation domain 28 90 4.9E-9 T 23-04-2016 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain DC74_RS08565 e0109231c6819b1e26dbf97858a93b13 480 SUPERFAMILY SSF103473 188 461 1.01E-22 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS08565 e0109231c6819b1e26dbf97858a93b13 480 Gene3D G3DSA:1.20.1250.20 267 467 2.8E-18 T 23-04-2016 DC74_RS08565 e0109231c6819b1e26dbf97858a93b13 480 Gene3D G3DSA:1.20.1250.20 4 175 6.9E-27 T 23-04-2016 DC74_RS08565 e0109231c6819b1e26dbf97858a93b13 480 Pfam PF07690 Major Facilitator Superfamily 6 178 2.6E-23 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS08565 e0109231c6819b1e26dbf97858a93b13 480 Pfam PF07690 Major Facilitator Superfamily 300 472 1.6E-10 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS08565 e0109231c6819b1e26dbf97858a93b13 480 SUPERFAMILY SSF103473 2 181 4.84E-32 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS08565 e0109231c6819b1e26dbf97858a93b13 480 PANTHER PTHR23501 1 478 5.7E-79 T 23-04-2016 DC74_RS14030 9cf1524a252487cf8248cd9d4467345b 318 Pfam PF00698 Acyl transferase domain 36 284 1.3E-19 T 23-04-2016 IPR014043 Acyl transferase DC74_RS14030 9cf1524a252487cf8248cd9d4467345b 318 Gene3D G3DSA:3.40.366.10 192 300 4.4E-49 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS14030 9cf1524a252487cf8248cd9d4467345b 318 Gene3D G3DSA:3.40.366.10 2 122 4.4E-49 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS14030 9cf1524a252487cf8248cd9d4467345b 318 Gene3D G3DSA:3.30.70.250 127 191 1.9E-23 T 23-04-2016 DC74_RS14030 9cf1524a252487cf8248cd9d4467345b 318 SUPERFAMILY SSF52151 185 306 1.86E-62 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS14030 9cf1524a252487cf8248cd9d4467345b 318 SUPERFAMILY SSF52151 2 122 1.86E-62 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS14030 9cf1524a252487cf8248cd9d4467345b 318 SUPERFAMILY SSF55048 130 188 7.46E-12 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS14030 9cf1524a252487cf8248cd9d4467345b 318 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 297 6.3E-17 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS14030 9cf1524a252487cf8248cd9d4467345b 318 PANTHER PTHR10982 3 305 5.0E-79 T 23-04-2016 DC74_RS37540 a41f7ec60dea71e689b90ba342fe8488 636 SMART SM00860 43 176 3.4E-7 T 23-04-2016 IPR018958 SMI1/KNR4-like domain DC74_RS37540 a41f7ec60dea71e689b90ba342fe8488 636 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 43 174 1.5E-6 T 23-04-2016 IPR018958 SMI1/KNR4-like domain DC74_RS37540 a41f7ec60dea71e689b90ba342fe8488 636 Gene3D G3DSA:3.40.1580.10 38 77 6.8E-6 T 23-04-2016 IPR018958 SMI1/KNR4-like domain DC74_RS37540 a41f7ec60dea71e689b90ba342fe8488 636 SUPERFAMILY SSF160631 37 178 5.1E-11 T 23-04-2016 DC74_RS06925 57e4e47bf1333990e653e9bd41dc9b56 212 Pfam PF13529 Peptidase_C39 like family 11 176 1.6E-8 T 23-04-2016 DC74_RS23420 cfc53d3af68990ddc9a16ff7167e89eb 371 PANTHER PTHR10804 136 351 2.6E-79 T 23-04-2016 DC74_RS23420 cfc53d3af68990ddc9a16ff7167e89eb 371 Gene3D G3DSA:3.90.230.10 145 369 3.3E-68 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS23420 cfc53d3af68990ddc9a16ff7167e89eb 371 SUPERFAMILY SSF53092 4 143 1.07E-11 T 23-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal DC74_RS23420 cfc53d3af68990ddc9a16ff7167e89eb 371 SUPERFAMILY SSF55920 144 370 2.62E-72 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS23420 cfc53d3af68990ddc9a16ff7167e89eb 371 Pfam PF00557 Metallopeptidase family M24 154 354 1.6E-55 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS23420 cfc53d3af68990ddc9a16ff7167e89eb 371 PANTHER PTHR10804:SF86 136 351 2.6E-79 T 23-04-2016 DC74_RS23420 cfc53d3af68990ddc9a16ff7167e89eb 371 Gene3D G3DSA:3.40.350.10 5 130 7.4E-10 T 23-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal DC74_RS23420 cfc53d3af68990ddc9a16ff7167e89eb 371 Pfam PF01321 Creatinase/Prolidase N-terminal domain 14 145 3.8E-10 T 23-04-2016 IPR000587 Creatinase, N-terminal GO:0016787 DC74_RS35330 55e8a2cb635e22c80f8ed54cac7dced7 141 Gene3D G3DSA:3.40.630.30 3 135 1.3E-27 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS35330 55e8a2cb635e22c80f8ed54cac7dced7 141 PANTHER PTHR23091 1 138 4.9E-27 T 23-04-2016 DC74_RS35330 55e8a2cb635e22c80f8ed54cac7dced7 141 PANTHER PTHR23091:SF276 1 138 4.9E-27 T 23-04-2016 DC74_RS35330 55e8a2cb635e22c80f8ed54cac7dced7 141 SUPERFAMILY SSF55729 1 135 2.03E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS35330 55e8a2cb635e22c80f8ed54cac7dced7 141 Pfam PF00583 Acetyltransferase (GNAT) family 51 126 9.5E-14 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS18780 7ec5c0adccaf2ec46dfd07e2e1c85455 128 Gene3D G3DSA:1.20.5.710 3 53 3.3E-17 T 23-04-2016 DC74_RS18780 7ec5c0adccaf2ec46dfd07e2e1c85455 128 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 54 2.1E-16 T 23-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18780 7ec5c0adccaf2ec46dfd07e2e1c85455 128 SUPERFAMILY SSF48300 5 64 9.16E-14 T 23-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18780 7ec5c0adccaf2ec46dfd07e2e1c85455 128 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 128 22.313 T 23-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18780 7ec5c0adccaf2ec46dfd07e2e1c85455 128 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 128 9.7E-45 T 23-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18780 7ec5c0adccaf2ec46dfd07e2e1c85455 128 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 63 101 4.0E-15 T 23-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 DC74_RS18780 7ec5c0adccaf2ec46dfd07e2e1c85455 128 SUPERFAMILY SSF54736 57 128 5.41E-22 T 23-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like DC74_RS18780 7ec5c0adccaf2ec46dfd07e2e1c85455 128 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 62 128 4.9E-27 T 23-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 DC74_RS18780 7ec5c0adccaf2ec46dfd07e2e1c85455 128 Gene3D G3DSA:3.30.1390.10 55 128 4.0E-30 T 23-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like DC74_RS03220 eac6c0991088f93a5f213466f97068f1 387 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 63 76 - T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS03220 eac6c0991088f93a5f213466f97068f1 387 SMART SM00839 153 384 5.9E-67 T 23-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 DC74_RS03220 eac6c0991088f93a5f213466f97068f1 387 SUPERFAMILY SSF53223 3 126 1.38E-23 T 23-04-2016 DC74_RS03220 eac6c0991088f93a5f213466f97068f1 387 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 157 375 2.0E-33 T 23-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 DC74_RS03220 eac6c0991088f93a5f213466f97068f1 387 Gene3D G3DSA:3.40.50.720 160 385 7.4E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03220 eac6c0991088f93a5f213466f97068f1 387 SUPERFAMILY SSF51735 157 385 1.13E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03220 eac6c0991088f93a5f213466f97068f1 387 Gene3D G3DSA:3.40.192.10 4 123 4.6E-22 T 23-04-2016 DC74_RS03220 eac6c0991088f93a5f213466f97068f1 387 PIRSF PIRSF000185 1 387 1.7E-99 T 23-04-2016 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 DC74_RS03220 eac6c0991088f93a5f213466f97068f1 387 PANTHER PTHR11606 13 114 1.4E-33 T 23-04-2016 DC74_RS03220 eac6c0991088f93a5f213466f97068f1 387 PANTHER PTHR11606 133 318 1.4E-33 T 23-04-2016 DC74_RS03220 eac6c0991088f93a5f213466f97068f1 387 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 12 96 4.0E-10 T 23-04-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 DC74_RS17500 f9e86b329d1f140acc6122be163c5429 194 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 175 2.3E-41 T 23-04-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 DC74_RS17500 f9e86b329d1f140acc6122be163c5429 194 Pfam PF01386 Ribosomal L25p family 6 90 3.0E-24 T 23-04-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 DC74_RS17500 f9e86b329d1f140acc6122be163c5429 194 Gene3D G3DSA:2.170.120.20 95 185 7.5E-21 T 23-04-2016 IPR020057 Ribosomal protein L25, beta domain DC74_RS17500 f9e86b329d1f140acc6122be163c5429 194 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 179 26.389 T 23-04-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 DC74_RS17500 f9e86b329d1f140acc6122be163c5429 194 SUPERFAMILY SSF50715 4 184 1.05E-47 T 23-04-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: REACT_71 DC74_RS17500 f9e86b329d1f140acc6122be163c5429 194 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 178 1.7E-18 T 23-04-2016 IPR020057 Ribosomal protein L25, beta domain DC74_RS17500 f9e86b329d1f140acc6122be163c5429 194 PANTHER PTHR33284 1 193 7.3E-51 T 23-04-2016 DC74_RS17500 f9e86b329d1f140acc6122be163c5429 194 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 89 1.0E-25 T 23-04-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 DC74_RS17500 f9e86b329d1f140acc6122be163c5429 194 Gene3D G3DSA:2.40.240.10 3 93 3.9E-29 T 23-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 DC74_RS07750 e790f3e15e5871b5465aba3e16283992 157 Gene3D G3DSA:3.10.450.50 15 147 1.5E-27 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS07750 e790f3e15e5871b5465aba3e16283992 157 SUPERFAMILY SSF54427 14 143 1.23E-31 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS07750 e790f3e15e5871b5465aba3e16283992 157 Pfam PF13577 SnoaL-like domain 16 137 4.5E-21 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS28815 b2716375537b124a9ec16e2bef0c0c11 303 SMART SM00062 65 289 2.2E-51 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS28815 b2716375537b124a9ec16e2bef0c0c11 303 Gene3D G3DSA:3.40.190.10 250 283 3.4E-28 T 23-04-2016 DC74_RS28815 b2716375537b124a9ec16e2bef0c0c11 303 Gene3D G3DSA:3.40.190.10 62 146 3.4E-28 T 23-04-2016 DC74_RS28815 b2716375537b124a9ec16e2bef0c0c11 303 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 89 102 - T 23-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 DC74_RS28815 b2716375537b124a9ec16e2bef0c0c11 303 SUPERFAMILY SSF53850 55 283 9.28E-56 T 23-04-2016 DC74_RS28815 b2716375537b124a9ec16e2bef0c0c11 303 SUPERFAMILY SSF53850 4 24 9.28E-56 T 23-04-2016 DC74_RS28815 b2716375537b124a9ec16e2bef0c0c11 303 Gene3D G3DSA:3.40.190.10 147 249 5.1E-24 T 23-04-2016 DC74_RS28815 b2716375537b124a9ec16e2bef0c0c11 303 PANTHER PTHR18966 64 282 2.6E-28 T 23-04-2016 DC74_RS28815 b2716375537b124a9ec16e2bef0c0c11 303 SMART SM00079 65 288 0.0072 T 23-04-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 DC74_RS28815 b2716375537b124a9ec16e2bef0c0c11 303 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 66 283 1.5E-47 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS28815 b2716375537b124a9ec16e2bef0c0c11 303 PANTHER PTHR18966:SF234 64 282 2.6E-28 T 23-04-2016 DC74_RS35975 6e92f2353ce7d2f244cfae469e4cb27b 331 PANTHER PTHR10459:SF36 43 330 1.4E-134 T 23-04-2016 DC74_RS35975 6e92f2353ce7d2f244cfae469e4cb27b 331 Pfam PF01896 DNA primase small subunit 131 251 1.1E-6 T 23-04-2016 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 DC74_RS35975 6e92f2353ce7d2f244cfae469e4cb27b 331 PANTHER PTHR10459 43 330 1.4E-134 T 23-04-2016 DC74_RS35975 6e92f2353ce7d2f244cfae469e4cb27b 331 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 10 255 2.1E-75 T 23-04-2016 IPR014145 DNA ligase D, polymerase domain DC74_RS03095 d9e8612e31e873862665a541f28ca5ba 352 PANTHER PTHR11835:SF37 3 352 3.4E-174 T 23-04-2016 DC74_RS03095 d9e8612e31e873862665a541f28ca5ba 352 PANTHER PTHR11835 3 352 3.4E-174 T 23-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 DC74_RS03095 d9e8612e31e873862665a541f28ca5ba 352 SMART SM01329 5 348 5.6E-154 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS03095 d9e8612e31e873862665a541f28ca5ba 352 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 350 1.8E-153 T 23-04-2016 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 DC74_RS03095 d9e8612e31e873862665a541f28ca5ba 352 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 347 8.5E-85 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS03095 d9e8612e31e873862665a541f28ca5ba 352 SUPERFAMILY SSF53659 2 352 1.37E-109 T 23-04-2016 DC74_RS03095 d9e8612e31e873862665a541f28ca5ba 352 Gene3D G3DSA:3.40.718.10 4 342 9.4E-109 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS03095 d9e8612e31e873862665a541f28ca5ba 352 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 241 260 - T 23-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 DC74_RS23075 3a8dc247c8deb9966a4e2ec8298b9f7c 124 SUPERFAMILY SSF54593 1 123 2.4E-16 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS23075 3a8dc247c8deb9966a4e2ec8298b9f7c 124 Gene3D G3DSA:3.10.180.10 4 122 9.6E-15 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS07170 bd8d5efc51001f435e393b28f6a7fb8b 302 Gene3D G3DSA:1.10.10.10 2 88 7.0E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07170 bd8d5efc51001f435e393b28f6a7fb8b 302 Gene3D G3DSA:3.40.190.10 182 271 2.7E-27 T 23-04-2016 DC74_RS07170 bd8d5efc51001f435e393b28f6a7fb8b 302 PANTHER PTHR30346 1 302 4.1E-115 T 23-04-2016 DC74_RS07170 bd8d5efc51001f435e393b28f6a7fb8b 302 PANTHER PTHR30346:SF2 1 302 4.1E-115 T 23-04-2016 DC74_RS07170 bd8d5efc51001f435e393b28f6a7fb8b 302 Gene3D G3DSA:3.40.190.10 89 181 1.2E-14 T 23-04-2016 DC74_RS07170 bd8d5efc51001f435e393b28f6a7fb8b 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.1E-18 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS07170 bd8d5efc51001f435e393b28f6a7fb8b 302 SUPERFAMILY SSF53850 89 301 4.78E-38 T 23-04-2016 DC74_RS07170 bd8d5efc51001f435e393b28f6a7fb8b 302 Pfam PF03466 LysR substrate binding domain 88 298 5.7E-40 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS07170 bd8d5efc51001f435e393b28f6a7fb8b 302 SUPERFAMILY SSF46785 2 112 9.09E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 PANTHER PTHR10357 1 305 6.5E-108 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 PANTHER PTHR10357 495 551 6.5E-108 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 Pfam PF00128 Alpha amylase, catalytic domain 120 195 6.7E-9 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 SUPERFAMILY SSF51445 81 517 4.9E-105 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 Gene3D G3DSA:3.20.20.80 98 432 3.2E-78 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 Gene3D G3DSA:3.20.20.80 482 516 3.2E-78 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 SUPERFAMILY SSF81296 2 82 1.64E-10 T 23-04-2016 IPR014756 Immunoglobulin E-set DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 Gene3D G3DSA:2.60.40.10 2 82 6.5E-19 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 PANTHER PTHR10357 326 462 6.5E-108 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 Pfam PF11941 Domain of unknown function (DUF3459) 502 607 5.1E-12 T 23-04-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 PANTHER PTHR10357:SF110 1 305 6.5E-108 T 23-04-2016 DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 PANTHER PTHR10357:SF110 326 462 6.5E-108 T 23-04-2016 DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 PANTHER PTHR10357:SF110 495 551 6.5E-108 T 23-04-2016 DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 SMART SM00642 83 451 2.9E-7 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 PIRSF PIRSF006337 1 582 5.5E-216 T 23-04-2016 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902|UniPathway: UPA00299 DC74_RS29960 1766a9e5ca8927b14246cfebbde90d61 623 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 3 551 2.2E-216 T 23-04-2016 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902|UniPathway: UPA00299 DC74_RS12375 dfc2eef09ba119bde0eede442f79b0ec 217 PIRSF PIRSF000495 9 217 4.4E-64 T 23-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 DC74_RS12375 dfc2eef09ba119bde0eede442f79b0ec 217 Gene3D G3DSA:3.40.50.880 9 215 4.3E-73 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS12375 dfc2eef09ba119bde0eede442f79b0ec 217 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 10 216 30.153 T 23-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 DC74_RS12375 dfc2eef09ba119bde0eede442f79b0ec 217 PANTHER PTHR21235 8 217 1.9E-84 T 23-04-2016 DC74_RS12375 dfc2eef09ba119bde0eede442f79b0ec 217 Pfam PF00117 Glutamine amidotransferase class-I 13 210 2.6E-18 T 23-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 DC74_RS12375 dfc2eef09ba119bde0eede442f79b0ec 217 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 11 215 1.2E-59 T 23-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 DC74_RS12375 dfc2eef09ba119bde0eede442f79b0ec 217 SUPERFAMILY SSF52317 9 215 2.07E-52 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS12375 dfc2eef09ba119bde0eede442f79b0ec 217 PANTHER PTHR21235:SF1 8 217 1.9E-84 T 23-04-2016 DC74_RS38415 a1cd12b474c41d11a13a3ab020a2c8da 259 PANTHER PTHR30296:SF0 2 247 4.9E-101 T 23-04-2016 DC74_RS38415 a1cd12b474c41d11a13a3ab020a2c8da 259 Pfam PF02754 Cysteine-rich domain 134 218 1.3E-14 T 23-04-2016 IPR004017 Cysteine-rich domain DC74_RS38415 a1cd12b474c41d11a13a3ab020a2c8da 259 Pfam PF02754 Cysteine-rich domain 4 80 5.6E-14 T 23-04-2016 IPR004017 Cysteine-rich domain DC74_RS38415 a1cd12b474c41d11a13a3ab020a2c8da 259 PANTHER PTHR30296 2 247 4.9E-101 T 23-04-2016 DC74_RS26000 d5f6eb98d66b12041c7c18cb8a3f98d4 388 PANTHER PTHR23264 11 368 3.4E-146 T 23-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein DC74_RS26000 d5f6eb98d66b12041c7c18cb8a3f98d4 388 SUPERFAMILY SSF52540 122 371 2.03E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26000 d5f6eb98d66b12041c7c18cb8a3f98d4 388 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 122 368 2.6E-92 T 23-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein DC74_RS26000 d5f6eb98d66b12041c7c18cb8a3f98d4 388 Gene3D G3DSA:3.40.50.300 112 367 1.9E-89 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26000 d5f6eb98d66b12041c7c18cb8a3f98d4 388 Hamap MF_02040 Iron-sulfur cluster carrier protein. 113 369 34.916 T 23-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein DC74_RS26000 d5f6eb98d66b12041c7c18cb8a3f98d4 388 ProSitePatterns PS01215 Mrp family signature. 226 242 - T 23-04-2016 IPR000808 Mrp, conserved site GO:0005524 DC74_RS26000 d5f6eb98d66b12041c7c18cb8a3f98d4 388 Pfam PF01883 Domain of unknown function DUF59 15 88 8.8E-19 T 23-04-2016 IPR002744 Domain of unknown function DUF59 DC74_RS26000 d5f6eb98d66b12041c7c18cb8a3f98d4 388 SUPERFAMILY SSF117916 13 98 5.56E-23 T 23-04-2016 DC74_RS26000 d5f6eb98d66b12041c7c18cb8a3f98d4 388 PANTHER PTHR23264:SF19 11 368 3.4E-146 T 23-04-2016 DC74_RS28415 77c8e7c5de08c017ca02efc406710807 167 SUPERFAMILY SSF47240 13 149 6.29E-35 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS28415 77c8e7c5de08c017ca02efc406710807 167 Gene3D G3DSA:1.20.1260.10 15 140 2.7E-43 T 23-04-2016 IPR012347 Ferritin-related DC74_RS28415 77c8e7c5de08c017ca02efc406710807 167 Pfam PF14530 Domain of unknown function (DUF4439) 19 148 3.0E-44 T 23-04-2016 IPR029447 Domain of unknown function DUF4439 DC74_RS10300 ffdf10d62a56d918a7eb2dcc4fbea48c 419 SUPERFAMILY SSF103473 14 386 4.45E-28 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS10300 ffdf10d62a56d918a7eb2dcc4fbea48c 419 PANTHER PTHR23542 2 419 8.1E-117 T 23-04-2016 DC74_RS10300 ffdf10d62a56d918a7eb2dcc4fbea48c 419 Pfam PF07690 Major Facilitator Superfamily 20 298 4.8E-12 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS10300 ffdf10d62a56d918a7eb2dcc4fbea48c 419 PANTHER PTHR23542:SF1 2 419 8.1E-117 T 23-04-2016 DC74_RS10300 ffdf10d62a56d918a7eb2dcc4fbea48c 419 Gene3D G3DSA:1.20.1250.20 20 199 2.4E-12 T 23-04-2016 DC74_RS10300 ffdf10d62a56d918a7eb2dcc4fbea48c 419 Gene3D G3DSA:1.20.1250.20 208 382 1.1E-7 T 23-04-2016 DC74_RS05390 3404284c6def6c8131214ec47b902618 351 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 74 302 1.8E-21 T 23-04-2016 IPR013658 SMP-30/Gluconolactonase/LRE-like region DC74_RS05390 3404284c6def6c8131214ec47b902618 351 SUPERFAMILY SSF63829 67 345 2.29E-42 T 23-04-2016 DC74_RS05390 3404284c6def6c8131214ec47b902618 351 Gene3D G3DSA:2.120.10.30 69 346 3.5E-40 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS17065 45965c234455ea523c0107c09a8546a6 431 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 186 340 1.1E-42 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS17065 45965c234455ea523c0107c09a8546a6 431 PANTHER PTHR33392:SF6 100 427 1.5E-89 T 23-04-2016 DC74_RS17065 45965c234455ea523c0107c09a8546a6 431 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 185 340 2.8E-37 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS17065 45965c234455ea523c0107c09a8546a6 431 PANTHER PTHR33392 100 427 1.5E-89 T 23-04-2016 DC74_RS25550 b6de940ead3c8f49ba0f8295c0f1d290 770 PANTHER PTHR32282 9 761 2.1E-264 T 23-04-2016 DC74_RS25550 b6de940ead3c8f49ba0f8295c0f1d290 770 SUPERFAMILY SSF53955 71 270 1.38E-60 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS25550 b6de940ead3c8f49ba0f8295c0f1d290 770 PANTHER PTHR32282:SF8 9 761 2.1E-264 T 23-04-2016 DC74_RS25550 b6de940ead3c8f49ba0f8295c0f1d290 770 Pfam PF00912 Transglycosylase 78 255 1.9E-56 T 23-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 DC74_RS25550 b6de940ead3c8f49ba0f8295c0f1d290 770 Pfam PF00905 Penicillin binding protein transpeptidase domain 354 604 5.3E-33 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS25550 b6de940ead3c8f49ba0f8295c0f1d290 770 Gene3D G3DSA:3.40.710.10 257 688 5.6E-99 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS25550 b6de940ead3c8f49ba0f8295c0f1d290 770 Gene3D G3DSA:1.10.3810.10 79 256 4.8E-62 T 23-04-2016 DC74_RS25550 b6de940ead3c8f49ba0f8295c0f1d290 770 SUPERFAMILY SSF56601 288 653 1.46E-78 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS25550 b6de940ead3c8f49ba0f8295c0f1d290 770 SUPERFAMILY SSF56601 241 259 1.46E-78 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS01690 eb67f4a6b0c80369cbd1b6719450195c 139 PANTHER PTHR30011 1 83 1.1E-16 T 23-04-2016 DC74_RS01690 eb67f4a6b0c80369cbd1b6719450195c 139 Pfam PF00296 Luciferase-like monooxygenase 2 91 8.6E-15 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS01690 eb67f4a6b0c80369cbd1b6719450195c 139 Gene3D G3DSA:3.20.20.30 2 93 1.0E-22 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS01690 eb67f4a6b0c80369cbd1b6719450195c 139 SUPERFAMILY SSF51679 2 133 3.93E-21 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS01690 eb67f4a6b0c80369cbd1b6719450195c 139 PANTHER PTHR30011:SF5 1 83 1.1E-16 T 23-04-2016 DC74_RS20475 13442c0ee24a6be8e57e6a835d976a86 236 SUPERFAMILY SSF47240 8 230 2.55E-61 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS20475 13442c0ee24a6be8e57e6a835d976a86 236 PANTHER PTHR30458 9 236 1.8E-80 T 23-04-2016 DC74_RS20475 13442c0ee24a6be8e57e6a835d976a86 236 PIRSF PIRSF037834 2 236 5.4E-89 T 23-04-2016 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 UniPathway: UPA00930 DC74_RS20475 13442c0ee24a6be8e57e6a835d976a86 236 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 9 236 1.3E-75 T 23-04-2016 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 UniPathway: UPA00930 DC74_RS20475 13442c0ee24a6be8e57e6a835d976a86 236 Pfam PF05138 Phenylacetic acid catabolic protein 8 236 1.3E-72 T 23-04-2016 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 UniPathway: UPA00930 DC74_RS20475 13442c0ee24a6be8e57e6a835d976a86 236 Gene3D G3DSA:1.20.1260.10 8 236 2.5E-78 T 23-04-2016 IPR012347 Ferritin-related DC74_RS20475 13442c0ee24a6be8e57e6a835d976a86 236 PANTHER PTHR30458:SF1 9 236 1.8E-80 T 23-04-2016 DC74_RS29990 43bc2e4a2580ecd4880ff677112b16d9 237 PANTHER PTHR30231 8 234 6.1E-59 T 23-04-2016 DC74_RS29990 43bc2e4a2580ecd4880ff677112b16d9 237 SMART SM00479 7 188 3.5E-19 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III DC74_RS29990 43bc2e4a2580ecd4880ff677112b16d9 237 SUPERFAMILY SSF53098 4 193 5.06E-44 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS29990 43bc2e4a2580ecd4880ff677112b16d9 237 Gene3D G3DSA:3.30.420.10 2 185 7.4E-38 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS29990 43bc2e4a2580ecd4880ff677112b16d9 237 PANTHER PTHR30231:SF9 8 234 6.1E-59 T 23-04-2016 DC74_RS29990 43bc2e4a2580ecd4880ff677112b16d9 237 Pfam PF00929 Exonuclease 9 177 4.5E-16 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III DC74_RS11530 3bb92b6770ece1634a228eb42152b6a0 464 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 8 451 2.2E-126 T 23-04-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 DC74_RS11530 3bb92b6770ece1634a228eb42152b6a0 464 SUPERFAMILY SSF52540 8 200 2.47E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11530 3bb92b6770ece1634a228eb42152b6a0 464 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 6 442 42.808 T 23-04-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 DC74_RS11530 3bb92b6770ece1634a228eb42152b6a0 464 SUPERFAMILY SSF52317 256 449 2.53E-31 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS11530 3bb92b6770ece1634a228eb42152b6a0 464 Gene3D G3DSA:3.40.50.300 7 197 1.3E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11530 3bb92b6770ece1634a228eb42152b6a0 464 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 9 181 2.5E-24 T 23-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DC74_RS11530 3bb92b6770ece1634a228eb42152b6a0 464 Gene3D G3DSA:3.40.50.880 257 450 2.9E-29 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS11530 3bb92b6770ece1634a228eb42152b6a0 464 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 259 441 1.8E-24 T 23-04-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 DC74_RS11530 3bb92b6770ece1634a228eb42152b6a0 464 PANTHER PTHR21343 261 454 5.8E-168 T 23-04-2016 DC74_RS11530 3bb92b6770ece1634a228eb42152b6a0 464 PANTHER PTHR21343 2 240 5.8E-168 T 23-04-2016 DC74_RS11530 3bb92b6770ece1634a228eb42152b6a0 464 PANTHER PTHR21343:SF6 261 454 5.8E-168 T 23-04-2016 DC74_RS11530 3bb92b6770ece1634a228eb42152b6a0 464 PANTHER PTHR21343:SF6 2 240 5.8E-168 T 23-04-2016 DC74_RS37380 3ad93b9e6d0444508a72f03b10f0241c 132 Pfam PF07045 Domain of unknown function (DUF1330) 36 110 6.1E-6 T 23-04-2016 IPR010753 Domain of unknown function DUF1330 DC74_RS37380 3ad93b9e6d0444508a72f03b10f0241c 132 SUPERFAMILY SSF54909 34 110 3.22E-12 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS37380 3ad93b9e6d0444508a72f03b10f0241c 132 Gene3D G3DSA:3.30.70.900 2 119 1.0E-34 T 23-04-2016 DC74_RS37380 3ad93b9e6d0444508a72f03b10f0241c 132 PANTHER PTHR40257:SF2 3 120 1.6E-14 T 23-04-2016 DC74_RS37380 3ad93b9e6d0444508a72f03b10f0241c 132 PANTHER PTHR40257 3 120 1.6E-14 T 23-04-2016 DC74_RS15105 ea643a6211b81e824333ca40d538839f 216 Gene3D G3DSA:3.10.560.10 63 113 4.3E-5 T 23-04-2016 DC74_RS15105 ea643a6211b81e824333ca40d538839f 216 Pfam PF10531 SLBB domain 63 115 9.8E-10 T 23-04-2016 IPR019554 Soluble ligand binding domain DC74_RS15105 ea643a6211b81e824333ca40d538839f 216 Gene3D G3DSA:1.10.150.280 154 215 2.2E-15 T 23-04-2016 DC74_RS15105 ea643a6211b81e824333ca40d538839f 216 SUPERFAMILY SSF47781 148 214 8.78E-23 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 DC74_RS15105 ea643a6211b81e824333ca40d538839f 216 PANTHER PTHR21180 37 215 9.4E-28 T 23-04-2016 DC74_RS15105 ea643a6211b81e824333ca40d538839f 216 Pfam PF12836 Helix-hairpin-helix motif 155 215 4.7E-18 T 23-04-2016 DC74_RS04980 0bbce60bd0c3fc3176d1bb7b9b44a7e9 199 SUPERFAMILY SSF56209 10 196 4.45E-80 T 23-04-2016 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 DC74_RS04980 0bbce60bd0c3fc3176d1bb7b9b44a7e9 199 PIRSF PIRSF001426 2 199 4.6E-93 T 23-04-2016 IPR023900 Nitrile hydratase alpha subunit /Thiocyanate hydrolase gamma subunit KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 DC74_RS04980 0bbce60bd0c3fc3176d1bb7b9b44a7e9 199 Gene3D G3DSA:3.90.330.10 10 198 1.8E-89 T 23-04-2016 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 DC74_RS04980 0bbce60bd0c3fc3176d1bb7b9b44a7e9 199 ProDom PD007559 HYDRATASE NITRILE ALPHA SUBUNIT LYASE CHAIN METAL-BINDING DIRECT SEQUENCING NITRILASE 16 196 3.0E-68 T 23-04-2016 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 DC74_RS04980 0bbce60bd0c3fc3176d1bb7b9b44a7e9 199 TIGRFAM TIGR01323 nitrile_alph: nitrile hydratase, alpha subunit 13 198 1.8E-91 T 23-04-2016 IPR018141 Nitrile hydratase, alpha subunit GO:0006807|GO:0018822|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 DC74_RS04980 0bbce60bd0c3fc3176d1bb7b9b44a7e9 199 Pfam PF02979 Nitrile hydratase, alpha chain 13 194 4.5E-87 T 23-04-2016 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 Gene3D G3DSA:3.40.50.720 3 237 9.7E-58 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 7.5E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 7.5E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 7.5E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 180 7.5E-4 T 23-04-2016 DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 PANTHER PTHR24322 7 176 4.7E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 237 1.2E-39 T 23-04-2016 DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 SUPERFAMILY SSF51735 3 237 1.98E-56 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 8.5E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 8.5E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 8.5E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 8.5E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 8.5E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS12245 0cb1e2edb354b4a76283d8396b585fbe 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 8.5E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03030 9ff4d28df986332238acbe7d65c123d2 414 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 157 173 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS03030 9ff4d28df986332238acbe7d65c123d2 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 258 369 3.2E-30 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS03030 9ff4d28df986332238acbe7d65c123d2 414 PANTHER PTHR11712 11 414 2.3E-127 T 23-04-2016 DC74_RS03030 9ff4d28df986332238acbe7d65c123d2 414 Gene3D G3DSA:3.40.47.10 266 412 2.8E-49 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS03030 9ff4d28df986332238acbe7d65c123d2 414 SUPERFAMILY SSF53901 217 413 3.49E-60 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS03030 9ff4d28df986332238acbe7d65c123d2 414 SUPERFAMILY SSF53901 10 253 5.49E-64 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS03030 9ff4d28df986332238acbe7d65c123d2 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 249 4.8E-49 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS03030 9ff4d28df986332238acbe7d65c123d2 414 Gene3D G3DSA:3.40.47.10 10 262 4.4E-62 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS03030 9ff4d28df986332238acbe7d65c123d2 414 SMART SM00825 Beta-ketoacyl synthase 10 404 7.6E-15 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS38490 8b8867fb3fe45605be3abf2545c8ecba 513 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 32 54 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS38490 8b8867fb3fe45605be3abf2545c8ecba 513 Gene3D G3DSA:3.30.200.20 22 102 8.9E-14 T 23-04-2016 DC74_RS38490 8b8867fb3fe45605be3abf2545c8ecba 513 SMART SM00220 26 280 2.3E-49 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS38490 8b8867fb3fe45605be3abf2545c8ecba 513 PANTHER PTHR24362 19 334 3.5E-83 T 23-04-2016 DC74_RS38490 8b8867fb3fe45605be3abf2545c8ecba 513 Gene3D G3DSA:1.10.510.10 107 272 4.2E-41 T 23-04-2016 DC74_RS38490 8b8867fb3fe45605be3abf2545c8ecba 513 PANTHER PTHR24362:SF247 19 334 3.5E-83 T 23-04-2016 DC74_RS38490 8b8867fb3fe45605be3abf2545c8ecba 513 SUPERFAMILY SSF56112 23 328 6.07E-66 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS38490 8b8867fb3fe45605be3abf2545c8ecba 513 Pfam PF00069 Protein kinase domain 26 271 3.8E-37 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS38490 8b8867fb3fe45605be3abf2545c8ecba 513 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 144 156 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS35890 b52c8f5be35b9b45949108fabf5eb62b 99 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 23-04-2016 IPR019812 Hydrogenase assembly chaperone, conserved site DC74_RS35890 b52c8f5be35b9b45949108fabf5eb62b 99 PANTHER PTHR35177:SF2 1 92 1.7E-28 T 23-04-2016 DC74_RS35890 b52c8f5be35b9b45949108fabf5eb62b 99 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 42 58 3.4E-15 T 23-04-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DC74_RS35890 b52c8f5be35b9b45949108fabf5eb62b 99 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 60 72 3.4E-15 T 23-04-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DC74_RS35890 b52c8f5be35b9b45949108fabf5eb62b 99 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 3.4E-15 T 23-04-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DC74_RS35890 b52c8f5be35b9b45949108fabf5eb62b 99 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 21 37 3.4E-15 T 23-04-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DC74_RS35890 b52c8f5be35b9b45949108fabf5eb62b 99 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 76 2.4E-22 T 23-04-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DC74_RS35890 b52c8f5be35b9b45949108fabf5eb62b 99 Pfam PF01455 HupF/HypC family 1 69 7.6E-27 T 23-04-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DC74_RS35890 b52c8f5be35b9b45949108fabf5eb62b 99 SUPERFAMILY SSF159127 1 80 6.54E-25 T 23-04-2016 DC74_RS35890 b52c8f5be35b9b45949108fabf5eb62b 99 PANTHER PTHR35177 1 92 1.7E-28 T 23-04-2016 DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 Pfam PF00271 Helicase conserved C-terminal domain 364 443 5.5E-5 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 SMART SM00487 32 214 6.4E-32 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 Pfam PF00270 DEAD/DEAH box helicase 38 186 3.1E-19 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 SMART SM00490 351 443 3.8E-12 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 PANTHER PTHR24031:SF122 367 398 9.8E-14 T 23-04-2016 DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 PANTHER PTHR24031:SF122 40 208 9.8E-14 T 23-04-2016 DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 PANTHER PTHR24031:SF122 289 325 9.8E-14 T 23-04-2016 DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 Gene3D G3DSA:3.40.50.300 34 216 1.7E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 Gene3D G3DSA:3.40.50.300 290 324 2.0E-17 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 Gene3D G3DSA:3.40.50.300 366 453 2.0E-17 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 Pfam PF13234 rRNA-processing arch domain 499 600 1.2E-4 T 23-04-2016 IPR025696 rRNA-processing arch domain DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 SMART SM01142 760 937 4.1E-62 T 23-04-2016 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 Pfam PF08148 DSHCT (NUC185) domain 763 932 3.2E-36 T 23-04-2016 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 SUPERFAMILY SSF52540 46 187 5.94E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 SUPERFAMILY SSF52540 269 321 5.94E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 SUPERFAMILY SSF52540 363 456 5.94E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 PANTHER PTHR24031 367 398 9.8E-14 T 23-04-2016 DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 PANTHER PTHR24031 40 208 9.8E-14 T 23-04-2016 DC74_RS10245 5ebee97582b7b5cca70b40b5797d5d95 938 PANTHER PTHR24031 289 325 9.8E-14 T 23-04-2016 DC74_RS09625 4ca821f4bb595c5005ba520afc11aa45 250 Gene3D G3DSA:1.10.10.200 1 77 1.7E-30 T 23-04-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like DC74_RS09625 4ca821f4bb595c5005ba520afc11aa45 250 Pfam PF01709 Transcriptional regulator 5 238 4.1E-87 T 23-04-2016 IPR002876 Transcriptional regulator TACO1-like DC74_RS09625 4ca821f4bb595c5005ba520afc11aa45 250 PANTHER PTHR12532:SF0 1 242 6.7E-104 T 23-04-2016 DC74_RS09625 4ca821f4bb595c5005ba520afc11aa45 250 SUPERFAMILY SSF75625 3 247 2.62E-88 T 23-04-2016 IPR029072 YebC-like DC74_RS09625 4ca821f4bb595c5005ba520afc11aa45 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.022 T 23-04-2016 IPR002876 Transcriptional regulator TACO1-like DC74_RS09625 4ca821f4bb595c5005ba520afc11aa45 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 2.2E-97 T 23-04-2016 IPR002876 Transcriptional regulator TACO1-like DC74_RS09625 4ca821f4bb595c5005ba520afc11aa45 250 PANTHER PTHR12532 1 242 6.7E-104 T 23-04-2016 IPR002876 Transcriptional regulator TACO1-like DC74_RS09625 4ca821f4bb595c5005ba520afc11aa45 250 Gene3D G3DSA:3.30.70.980 138 205 4.8E-24 T 23-04-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 DC74_RS09625 4ca821f4bb595c5005ba520afc11aa45 250 Gene3D G3DSA:3.30.1270.10 213 248 5.9E-40 T 23-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 DC74_RS09625 4ca821f4bb595c5005ba520afc11aa45 250 Gene3D G3DSA:3.30.1270.10 83 137 5.9E-40 T 23-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 DC74_RS37090 da5905d8a0dbab8d250ecee83c5b8730 270 PANTHER PTHR30011:SF5 17 216 4.7E-27 T 23-04-2016 DC74_RS37090 da5905d8a0dbab8d250ecee83c5b8730 270 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 20 254 2.5E-51 T 23-04-2016 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted DC74_RS37090 da5905d8a0dbab8d250ecee83c5b8730 270 PANTHER PTHR30011 17 216 4.7E-27 T 23-04-2016 DC74_RS37090 da5905d8a0dbab8d250ecee83c5b8730 270 SUPERFAMILY SSF51679 5 257 7.4E-43 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS37090 da5905d8a0dbab8d250ecee83c5b8730 270 Gene3D G3DSA:3.20.20.30 4 249 1.5E-49 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS37090 da5905d8a0dbab8d250ecee83c5b8730 270 Pfam PF00296 Luciferase-like monooxygenase 10 244 1.8E-39 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS17325 ca22fd7de3b4e72c3214be65461a37ed 260 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS17325 ca22fd7de3b4e72c3214be65461a37ed 260 Pfam PF00005 ABC transporter 38 184 9.3E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS17325 ca22fd7de3b4e72c3214be65461a37ed 260 PANTHER PTHR24220:SF484 20 259 7.9E-161 T 23-04-2016 DC74_RS17325 ca22fd7de3b4e72c3214be65461a37ed 260 SUPERFAMILY SSF52540 21 238 6.05E-69 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17325 ca22fd7de3b4e72c3214be65461a37ed 260 PANTHER PTHR24220 20 259 7.9E-161 T 23-04-2016 DC74_RS17325 ca22fd7de3b4e72c3214be65461a37ed 260 Gene3D G3DSA:3.40.50.300 21 237 1.3E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17325 ca22fd7de3b4e72c3214be65461a37ed 260 SMART SM00382 47 233 5.6E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS32045 e3cb1742032b302672d0cd9384ffab38 313 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 1.2E-6 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS32045 e3cb1742032b302672d0cd9384ffab38 313 PANTHER PTHR11695 15 313 9.1E-77 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS32045 e3cb1742032b302672d0cd9384ffab38 313 Pfam PF13602 Zinc-binding dehydrogenase 184 311 5.1E-21 T 23-04-2016 DC74_RS32045 e3cb1742032b302672d0cd9384ffab38 313 SUPERFAMILY SSF50129 2 149 1.02E-27 T 23-04-2016 IPR011032 GroES-like DC74_RS32045 e3cb1742032b302672d0cd9384ffab38 313 SMART SM00829 10 311 3.2E-14 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS32045 e3cb1742032b302672d0cd9384ffab38 313 Gene3D G3DSA:3.40.50.720 146 250 2.8E-23 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32045 e3cb1742032b302672d0cd9384ffab38 313 Gene3D G3DSA:3.90.180.10 2 145 3.0E-33 T 23-04-2016 IPR011032 GroES-like DC74_RS32045 e3cb1742032b302672d0cd9384ffab38 313 PANTHER PTHR11695:SF605 15 313 9.1E-77 T 23-04-2016 DC74_RS32045 e3cb1742032b302672d0cd9384ffab38 313 SUPERFAMILY SSF51735 114 278 1.02E-31 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 SUPERFAMILY SSF47802 5 85 2.62E-15 T 23-04-2016 IPR010996 DNA polymerase beta-like, N-terminal domain DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 SMART SM00483 3 317 1.2E-13 T 23-04-2016 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 255 262 4.9E-7 T 23-04-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 240 248 4.9E-7 T 23-04-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 59 76 4.9E-7 T 23-04-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 Gene3D G3DSA:1.10.8.310 4 85 2.7E-17 T 23-04-2016 IPR027420 DNA polymerase beta, N-terminal domain DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 PIRSF PIRSF005047 3 574 3.9E-205 T 23-04-2016 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 Pfam PF14791 DNA polymerase beta thumb 256 317 1.0E-20 T 23-04-2016 IPR029398 DNA polymerase beta, thumb domain DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 SUPERFAMILY SSF158702 61 148 9.42E-6 T 23-04-2016 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 Pfam PF02811 PHP domain 342 448 9.3E-7 T 23-04-2016 IPR004013 PHP domain GO:0003824 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 Gene3D G3DSA:3.30.460.10 142 256 4.3E-14 T 23-04-2016 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 Gene3D G3DSA:3.30.210.10 257 317 1.0E-22 T 23-04-2016 IPR029398 DNA polymerase beta, thumb domain DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 PANTHER PTHR11276 5 321 4.5E-67 T 23-04-2016 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 SMART SM00481 341 419 1.1E-12 T 23-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 SUPERFAMILY SSF81301 157 317 5.45E-39 T 23-04-2016 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 Pfam PF14520 Helix-hairpin-helix domain 92 144 1.0E-9 T 23-04-2016 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 Gene3D G3DSA:3.20.20.140 339 570 2.7E-49 T 23-04-2016 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 SMART SM00278 52 71 88.0 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 SMART SM00278 92 111 7.7 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 SMART SM00278 127 146 34.0 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 SUPERFAMILY SSF89550 340 572 1.14E-49 T 23-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 DC74_RS34545 fb9d3cda9a8dae1281c56cf5d6113b8a 575 Pfam PF14716 Helix-hairpin-helix domain 5 72 5.5E-19 T 23-04-2016 IPR010996 DNA polymerase beta-like, N-terminal domain DC74_RS14180 c35e84a9ac945e8625d706e5315a9869 251 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 44 175 5.9E-19 T 23-04-2016 IPR006342 Methyltransferase FkbM KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS14180 c35e84a9ac945e8625d706e5315a9869 251 Pfam PF05050 Methyltransferase FkbM domain 55 195 8.1E-12 T 23-04-2016 IPR006342 Methyltransferase FkbM KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS14180 c35e84a9ac945e8625d706e5315a9869 251 Gene3D G3DSA:3.40.50.150 28 213 2.7E-35 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14180 c35e84a9ac945e8625d706e5315a9869 251 PANTHER PTHR34203 45 173 1.2E-13 T 23-04-2016 DC74_RS14180 c35e84a9ac945e8625d706e5315a9869 251 SUPERFAMILY SSF53335 27 204 6.8E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS25915 c11a2e2379a0d1c93aaa250975ef19b5 351 Pfam PF00583 Acetyltransferase (GNAT) family 277 332 7.1E-10 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS25915 c11a2e2379a0d1c93aaa250975ef19b5 351 Gene3D G3DSA:3.40.630.30 212 345 8.1E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS25915 c11a2e2379a0d1c93aaa250975ef19b5 351 PANTHER PTHR20958 260 351 1.9E-13 T 23-04-2016 DC74_RS25915 c11a2e2379a0d1c93aaa250975ef19b5 351 SUPERFAMILY SSF55729 212 341 7.27E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS21270 2ca4f07cc7546f22358371bdbf59b333 236 Gene3D G3DSA:1.10.357.10 65 200 4.9E-36 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS21270 2ca4f07cc7546f22358371bdbf59b333 236 Pfam PF16859 Bacterial transcriptional repressor C-terminal 80 191 3.3E-29 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS21270 2ca4f07cc7546f22358371bdbf59b333 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 67 1.2E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS21270 2ca4f07cc7546f22358371bdbf59b333 236 PANTHER PTHR30328 7 206 8.7E-38 T 23-04-2016 DC74_RS21270 2ca4f07cc7546f22358371bdbf59b333 236 PANTHER PTHR30328:SF2 7 206 8.7E-38 T 23-04-2016 DC74_RS21270 2ca4f07cc7546f22358371bdbf59b333 236 SUPERFAMILY SSF46689 15 74 1.12E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS21270 2ca4f07cc7546f22358371bdbf59b333 236 SUPERFAMILY SSF48498 81 198 1.28E-23 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS21270 2ca4f07cc7546f22358371bdbf59b333 236 Gene3D G3DSA:1.10.10.60 14 62 1.3E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07465 1453a1b9cff3d8508f2ebdf0a2cfe900 354 SMART SM00710 110 132 200.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS07465 1453a1b9cff3d8508f2ebdf0a2cfe900 354 SMART SM00710 211 232 230.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS07465 1453a1b9cff3d8508f2ebdf0a2cfe900 354 SMART SM00710 133 178 770.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS07465 1453a1b9cff3d8508f2ebdf0a2cfe900 354 SMART SM00710 239 274 1400.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS07465 1453a1b9cff3d8508f2ebdf0a2cfe900 354 SMART SM00710 189 210 7500.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS07465 1453a1b9cff3d8508f2ebdf0a2cfe900 354 SMART SM00710 275 302 2100.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS07465 1453a1b9cff3d8508f2ebdf0a2cfe900 354 Gene3D G3DSA:2.160.20.10 25 342 2.5E-26 T 23-04-2016 IPR012334 Pectin lyase fold DC74_RS07465 1453a1b9cff3d8508f2ebdf0a2cfe900 354 Pfam PF13229 Right handed beta helix region 97 234 7.2E-13 T 23-04-2016 DC74_RS07465 1453a1b9cff3d8508f2ebdf0a2cfe900 354 SUPERFAMILY SSF51126 25 343 1.37E-35 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS28850 0c3d1bb48b58c6abe9626f31c4467c98 485 Pfam PF04055 Radical SAM superfamily 140 310 5.7E-31 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS28850 0c3d1bb48b58c6abe9626f31c4467c98 485 Pfam PF00919 Uncharacterized protein family UPF0004 1 93 2.0E-20 T 23-04-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 DC74_RS28850 0c3d1bb48b58c6abe9626f31c4467c98 485 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 1 429 7.4E-141 T 23-04-2016 DC74_RS28850 0c3d1bb48b58c6abe9626f31c4467c98 485 PANTHER PTHR11918:SF43 1 430 4.3E-173 T 23-04-2016 DC74_RS28850 0c3d1bb48b58c6abe9626f31c4467c98 485 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 433 65.792 T 23-04-2016 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 DC74_RS28850 0c3d1bb48b58c6abe9626f31c4467c98 485 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 1 428 2.4E-146 T 23-04-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 DC74_RS28850 0c3d1bb48b58c6abe9626f31c4467c98 485 Gene3D G3DSA:3.80.30.20 136 367 5.1E-85 T 23-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe DC74_RS28850 0c3d1bb48b58c6abe9626f31c4467c98 485 SUPERFAMILY SSF102114 122 361 3.53E-59 T 23-04-2016 DC74_RS28850 0c3d1bb48b58c6abe9626f31c4467c98 485 SMART SM00729 136 355 7.6E-61 T 23-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 DC74_RS28850 0c3d1bb48b58c6abe9626f31c4467c98 485 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 140 160 - T 23-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 DC74_RS28850 0c3d1bb48b58c6abe9626f31c4467c98 485 PANTHER PTHR11918 1 430 4.3E-173 T 23-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein DC74_RS01930 cea49d0212b169ac61da06af711bb234 439 Pfam PF00202 Aminotransferase class-III 37 426 4.2E-79 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS01930 cea49d0212b169ac61da06af711bb234 439 Gene3D G3DSA:3.90.1150.10 311 429 1.9E-28 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS01930 cea49d0212b169ac61da06af711bb234 439 SUPERFAMILY SSF53383 31 427 6.34E-92 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS01930 cea49d0212b169ac61da06af711bb234 439 Gene3D G3DSA:3.40.640.10 68 310 5.4E-64 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS01930 cea49d0212b169ac61da06af711bb234 439 PANTHER PTHR11986 39 435 2.6E-99 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS01930 cea49d0212b169ac61da06af711bb234 439 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 245 282 - T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS09115 7fd91568d848790e970a12f6e2c4e701 418 PANTHER PTHR23517 11 408 1.9E-23 T 23-04-2016 DC74_RS09115 7fd91568d848790e970a12f6e2c4e701 418 Gene3D G3DSA:1.20.1250.20 13 194 4.9E-16 T 23-04-2016 DC74_RS09115 7fd91568d848790e970a12f6e2c4e701 418 Pfam PF07690 Major Facilitator Superfamily 14 355 8.3E-21 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS09115 7fd91568d848790e970a12f6e2c4e701 418 SUPERFAMILY SSF103473 9 390 1.96E-30 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS09115 7fd91568d848790e970a12f6e2c4e701 418 Gene3D G3DSA:1.20.1250.20 202 363 4.8E-8 T 23-04-2016 DC74_RS21730 29d6c6ba7ced0f9f92b1f07091006810 343 SUPERFAMILY SSF53335 45 309 2.92E-40 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS21730 29d6c6ba7ced0f9f92b1f07091006810 343 PANTHER PTHR10108 48 179 1.1E-29 T 23-04-2016 DC74_RS21730 29d6c6ba7ced0f9f92b1f07091006810 343 Gene3D G3DSA:3.40.50.150 48 264 2.6E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS21730 29d6c6ba7ced0f9f92b1f07091006810 343 Pfam PF08241 Methyltransferase domain 80 179 8.8E-24 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 13 401 1.5E-120 T 23-04-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 PANTHER PTHR11820:SF1 291 401 5.6E-145 T 23-04-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 PANTHER PTHR11820:SF1 1 91 5.6E-145 T 23-04-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 PANTHER PTHR11820:SF1 117 272 5.6E-145 T 23-04-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 SUPERFAMILY SSF56529 119 400 6.41E-89 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 123 397 2.1E-55 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 Pfam PF09298 Fumarylacetoacetase N-terminal 19 117 7.7E-16 T 23-04-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 Gene3D G3DSA:2.30.30.230 8 119 1.2E-23 T 23-04-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 Gene3D G3DSA:3.90.850.10 120 393 1.4E-100 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 SUPERFAMILY SSF63433 6 117 1.44E-20 T 23-04-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 PANTHER PTHR11820 291 401 5.6E-145 T 23-04-2016 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 PANTHER PTHR11820 1 91 5.6E-145 T 23-04-2016 DC74_RS18995 44b012b456d3cfefeeedbb57044eb65d 409 PANTHER PTHR11820 117 272 5.6E-145 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 Gene3D G3DSA:2.70.150.10 52 221 4.7E-21 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 489 499 3.2E-25 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 561 3.2E-25 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 577 3.2E-25 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 318 332 3.2E-25 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 167 181 3.2E-25 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 26 702 3.6E-300 T 23-04-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 320 326 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 Pfam PF00122 E1-E2 ATPase 82 309 5.0E-40 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 Gene3D G3DSA:3.40.1110.10 329 469 6.5E-46 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 SUPERFAMILY SSF81665 221 312 2.22E-12 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 SUPERFAMILY SSF81665 49 113 2.22E-12 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 PANTHER PTHR24093 651 702 0.0 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 PANTHER PTHR24093 33 613 0.0 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 Pfam PF00702 haloacid dehalogenase-like hydrolase 314 556 4.5E-34 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 SUPERFAMILY SSF81660 329 477 3.6E-27 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 SUPERFAMILY SSF81653 131 220 6.15E-20 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 Gene3D G3DSA:3.40.50.1000 470 589 4.3E-38 T 23-04-2016 IPR023214 HAD-like domain DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 25 706 40.018 T 23-04-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 356 2.7E-29 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 460 624 3.1E-40 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 SUPERFAMILY SSF56784 461 585 2.42E-38 T 23-04-2016 IPR023214 HAD-like domain DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 SUPERFAMILY SSF56784 306 330 2.42E-38 T 23-04-2016 IPR023214 HAD-like domain DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 PANTHER PTHR24093:SF49 651 702 0.0 T 23-04-2016 DC74_RS01805 a55560a5c3b175394f08bbf6abef0ce9 709 PANTHER PTHR24093:SF49 33 613 0.0 T 23-04-2016 DC74_RS19085 b6a0737e1a8254023c3709c51cfb1985 437 PANTHER PTHR10617 1 420 1.5E-104 T 23-04-2016 DC74_RS19085 b6a0737e1a8254023c3709c51cfb1985 437 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 21 343 1.1E-88 T 23-04-2016 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 DC74_RS19085 b6a0737e1a8254023c3709c51cfb1985 437 Gene3D G3DSA:3.50.50.60 19 187 9.9E-22 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19085 b6a0737e1a8254023c3709c51cfb1985 437 Gene3D G3DSA:3.30.9.10 188 352 2.9E-51 T 23-04-2016 DC74_RS19085 b6a0737e1a8254023c3709c51cfb1985 437 PANTHER PTHR10617:SF101 1 420 1.5E-104 T 23-04-2016 DC74_RS19085 b6a0737e1a8254023c3709c51cfb1985 437 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 21 43 3.4E-10 T 23-04-2016 DC74_RS19085 b6a0737e1a8254023c3709c51cfb1985 437 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 171 186 3.4E-10 T 23-04-2016 DC74_RS19085 b6a0737e1a8254023c3709c51cfb1985 437 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 323 3.4E-10 T 23-04-2016 DC74_RS19085 b6a0737e1a8254023c3709c51cfb1985 437 SUPERFAMILY SSF51905 298 390 2.39E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19085 b6a0737e1a8254023c3709c51cfb1985 437 SUPERFAMILY SSF51905 17 202 2.39E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19085 b6a0737e1a8254023c3709c51cfb1985 437 Pfam PF01494 FAD binding domain 20 198 1.7E-11 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS14170 35d6a11ad7d916997756dac687e5b56d 301 SUPERFAMILY SSF103481 43 120 3.4E-5 T 23-04-2016 DC74_RS14170 35d6a11ad7d916997756dac687e5b56d 301 PANTHER PTHR40761 1 293 1.3E-18 T 23-04-2016 DC74_RS14170 35d6a11ad7d916997756dac687e5b56d 301 Pfam PF05653 Magnesium transporter NIPA 4 286 2.8E-12 T 23-04-2016 IPR008521 Magnesium transporter NIPA GO:0015095|GO:0015693|GO:0016021 DC74_RS04255 df08b41e6e10d98c47e8e00335834d71 136 PANTHER PTHR33570 17 132 1.7E-25 T 23-04-2016 DC74_RS04255 df08b41e6e10d98c47e8e00335834d71 136 PANTHER PTHR33570:SF5 17 132 1.7E-25 T 23-04-2016 DC74_RS04255 df08b41e6e10d98c47e8e00335834d71 136 Gene3D G3DSA:2.60.120.10 7 129 1.7E-28 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS04255 df08b41e6e10d98c47e8e00335834d71 136 SUPERFAMILY SSF51182 9 131 6.45E-28 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS04255 df08b41e6e10d98c47e8e00335834d71 136 Pfam PF07883 Cupin domain 38 100 2.4E-12 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS25000 da1b29a58d4bd0e82c722ccd9a8e44ea 216 Gene3D G3DSA:1.10.10.10 138 197 2.2E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25000 da1b29a58d4bd0e82c722ccd9a8e44ea 216 SUPERFAMILY SSF88659 136 197 5.42E-17 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS25000 da1b29a58d4bd0e82c722ccd9a8e44ea 216 Gene3D G3DSA:1.10.1740.10 42 117 6.3E-18 T 23-04-2016 DC74_RS25000 da1b29a58d4bd0e82c722ccd9a8e44ea 216 Pfam PF08281 Sigma-70, region 4 144 195 1.1E-14 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS25000 da1b29a58d4bd0e82c722ccd9a8e44ea 216 Pfam PF04542 Sigma-70 region 2 54 117 4.8E-12 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS25000 da1b29a58d4bd0e82c722ccd9a8e44ea 216 PANTHER PTHR30173 23 197 5.2E-33 T 23-04-2016 DC74_RS25000 da1b29a58d4bd0e82c722ccd9a8e44ea 216 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 197 1.9E-25 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS25000 da1b29a58d4bd0e82c722ccd9a8e44ea 216 SUPERFAMILY SSF88946 43 131 6.67E-16 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS25000 da1b29a58d4bd0e82c722ccd9a8e44ea 216 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 43 199 1.3E-60 T 23-04-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 DC74_RS12795 a72346ea81a4bc4d210e1c537e37743c 380 SUPERFAMILY SSF53756 5 380 4.71E-76 T 23-04-2016 DC74_RS12795 a72346ea81a4bc4d210e1c537e37743c 380 PANTHER PTHR12526 3 41 4.6E-126 T 23-04-2016 DC74_RS12795 a72346ea81a4bc4d210e1c537e37743c 380 PANTHER PTHR12526 65 380 4.6E-126 T 23-04-2016 DC74_RS12795 a72346ea81a4bc4d210e1c537e37743c 380 Gene3D G3DSA:3.40.50.2000 167 360 9.9E-40 T 23-04-2016 DC74_RS12795 a72346ea81a4bc4d210e1c537e37743c 380 PANTHER PTHR12526:SF353 3 41 4.6E-126 T 23-04-2016 DC74_RS12795 a72346ea81a4bc4d210e1c537e37743c 380 PANTHER PTHR12526:SF353 65 380 4.6E-126 T 23-04-2016 DC74_RS12795 a72346ea81a4bc4d210e1c537e37743c 380 Pfam PF00534 Glycosyl transferases group 1 197 362 1.3E-42 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 DC74_RS12795 a72346ea81a4bc4d210e1c537e37743c 380 Pfam PF13439 Glycosyltransferase Family 4 16 178 1.2E-7 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain DC74_RS18340 4b0f395aab07f9edd1f9cdfbfcf829ef 277 Gene3D G3DSA:3.90.226.10 20 218 6.5E-67 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS18340 4b0f395aab07f9edd1f9cdfbfcf829ef 277 PANTHER PTHR11941 4 274 1.5E-85 T 23-04-2016 DC74_RS18340 4b0f395aab07f9edd1f9cdfbfcf829ef 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 25 276 7.3E-63 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS18340 4b0f395aab07f9edd1f9cdfbfcf829ef 277 Gene3D G3DSA:1.10.12.10 219 277 2.4E-17 T 23-04-2016 IPR014748 Crontonase, C-terminal DC74_RS18340 4b0f395aab07f9edd1f9cdfbfcf829ef 277 SUPERFAMILY SSF52096 20 277 7.76E-86 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS12145 166992ed9611d8c61a3d6e2c8d8e12c0 478 PANTHER PTHR23024:SF215 63 140 4.1E-39 T 23-04-2016 DC74_RS12145 166992ed9611d8c61a3d6e2c8d8e12c0 478 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 21 365 3.4E-114 T 23-04-2016 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase DC74_RS12145 166992ed9611d8c61a3d6e2c8d8e12c0 478 SUPERFAMILY SSF51905 19 283 4.91E-15 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12145 166992ed9611d8c61a3d6e2c8d8e12c0 478 Gene3D G3DSA:3.50.50.60 107 224 3.0E-8 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12145 166992ed9611d8c61a3d6e2c8d8e12c0 478 PANTHER PTHR23024 63 140 4.1E-39 T 23-04-2016 DC74_RS12145 166992ed9611d8c61a3d6e2c8d8e12c0 478 Gene3D G3DSA:3.50.50.60 225 375 1.6E-4 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33345 127273c360ae91fe30057caa60a9d8dd 136 PANTHER PTHR36221 1 135 3.2E-32 T 23-04-2016 DC74_RS33345 127273c360ae91fe30057caa60a9d8dd 136 Pfam PF05331 Protein of unknown function (DUF742) 23 134 5.9E-33 T 23-04-2016 IPR007995 Protein of unknown function DUF742 DC74_RS21145 9e087b057e77720abce157f9375f0eaf 340 SUPERFAMILY SSF53850 89 301 4.74E-28 T 23-04-2016 DC74_RS21145 9e087b057e77720abce157f9375f0eaf 340 SUPERFAMILY SSF46785 2 109 4.9E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21145 9e087b057e77720abce157f9375f0eaf 340 Gene3D G3DSA:3.40.190.10 177 271 1.5E-10 T 23-04-2016 DC74_RS21145 9e087b057e77720abce157f9375f0eaf 340 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.5E-5 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS21145 9e087b057e77720abce157f9375f0eaf 340 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.5E-5 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS21145 9e087b057e77720abce157f9375f0eaf 340 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.5E-5 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS21145 9e087b057e77720abce157f9375f0eaf 340 Gene3D G3DSA:1.10.10.10 2 86 7.4E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21145 9e087b057e77720abce157f9375f0eaf 340 Gene3D G3DSA:3.40.190.10 89 176 3.1E-14 T 23-04-2016 DC74_RS21145 9e087b057e77720abce157f9375f0eaf 340 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.0E-20 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS21145 9e087b057e77720abce157f9375f0eaf 340 PANTHER PTHR30346 1 295 3.6E-48 T 23-04-2016 DC74_RS21145 9e087b057e77720abce157f9375f0eaf 340 Pfam PF03466 LysR substrate binding domain 87 296 8.9E-28 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS11665 d3383dedaad3d5740b3ea8acb743c784 338 SUPERFAMILY SSF51679 5 330 2.62E-62 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS11665 d3383dedaad3d5740b3ea8acb743c784 338 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 6 330 1.4E-101 T 23-04-2016 IPR019949 Luciferase family oxidoreductase, group 1 DC74_RS11665 d3383dedaad3d5740b3ea8acb743c784 338 PANTHER PTHR30137 1 331 2.8E-96 T 23-04-2016 DC74_RS11665 d3383dedaad3d5740b3ea8acb743c784 338 PANTHER PTHR30137:SF2 1 331 2.8E-96 T 23-04-2016 DC74_RS11665 d3383dedaad3d5740b3ea8acb743c784 338 Gene3D G3DSA:3.20.20.30 5 330 1.8E-75 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS11665 d3383dedaad3d5740b3ea8acb743c784 338 Pfam PF00296 Luciferase-like monooxygenase 5 304 1.5E-37 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS37990 e1f234d9c128f70e19c338b47b727ac8 221 Pfam PF03737 Demethylmenaquinone methyltransferase 20 166 2.9E-40 T 23-04-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein DC74_RS37990 e1f234d9c128f70e19c338b47b727ac8 221 PANTHER PTHR33254 11 188 7.8E-40 T 23-04-2016 DC74_RS37990 e1f234d9c128f70e19c338b47b727ac8 221 SUPERFAMILY SSF89562 15 176 1.57E-42 T 23-04-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein DC74_RS37990 e1f234d9c128f70e19c338b47b727ac8 221 PANTHER PTHR33254:SF5 11 188 7.8E-40 T 23-04-2016 DC74_RS37990 e1f234d9c128f70e19c338b47b727ac8 221 Gene3D G3DSA:3.50.30.40 16 175 1.0E-46 T 23-04-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein DC74_RS36610 a7bc0405b1526668426d0ebf16721722 485 PANTHER PTHR24322 395 428 4.6E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36610 a7bc0405b1526668426d0ebf16721722 485 PANTHER PTHR24322 153 242 4.6E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36610 a7bc0405b1526668426d0ebf16721722 485 PANTHER PTHR24322 333 375 4.6E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36610 a7bc0405b1526668426d0ebf16721722 485 PANTHER PTHR24322:SF506 395 428 4.6E-48 T 23-04-2016 DC74_RS36610 a7bc0405b1526668426d0ebf16721722 485 PANTHER PTHR24322:SF506 153 242 4.6E-48 T 23-04-2016 DC74_RS36610 a7bc0405b1526668426d0ebf16721722 485 PANTHER PTHR24322:SF506 333 375 4.6E-48 T 23-04-2016 DC74_RS36610 a7bc0405b1526668426d0ebf16721722 485 SUPERFAMILY SSF51735 330 430 9.38E-26 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36610 a7bc0405b1526668426d0ebf16721722 485 SUPERFAMILY SSF51735 145 243 9.38E-26 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36610 a7bc0405b1526668426d0ebf16721722 485 Gene3D G3DSA:3.40.50.720 325 463 1.1E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36610 a7bc0405b1526668426d0ebf16721722 485 Gene3D G3DSA:3.40.50.720 132 235 1.1E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36610 a7bc0405b1526668426d0ebf16721722 485 Pfam PF00106 short chain dehydrogenase 151 239 2.5E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22385 e4a839bdbf1814bb0da012bd2699704f 207 PANTHER PTHR30546 1 202 8.2E-48 T 23-04-2016 DC74_RS22385 e4a839bdbf1814bb0da012bd2699704f 207 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 6 198 2.3E-42 T 23-04-2016 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 DC74_RS22385 e4a839bdbf1814bb0da012bd2699704f 207 Gene3D G3DSA:3.40.50.360 4 201 2.9E-60 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS22385 e4a839bdbf1814bb0da012bd2699704f 207 SUPERFAMILY SSF52218 7 199 3.8E-47 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS22385 e4a839bdbf1814bb0da012bd2699704f 207 PANTHER PTHR30546:SF0 1 202 8.2E-48 T 23-04-2016 DC74_RS22385 e4a839bdbf1814bb0da012bd2699704f 207 Pfam PF03358 NADPH-dependent FMN reductase 16 133 2.8E-14 T 23-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 DC74_RS08685 34fd99d92927ee31e5cf92bbd9915a69 406 Gene3D G3DSA:3.50.50.60 4 171 2.1E-18 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08685 34fd99d92927ee31e5cf92bbd9915a69 406 SUPERFAMILY SSF51905 17 187 8.65E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08685 34fd99d92927ee31e5cf92bbd9915a69 406 SUPERFAMILY SSF51905 280 369 8.65E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08685 34fd99d92927ee31e5cf92bbd9915a69 406 Pfam PF01494 FAD binding domain 16 357 1.1E-55 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS08685 34fd99d92927ee31e5cf92bbd9915a69 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 17 39 2.8E-25 T 23-04-2016 DC74_RS08685 34fd99d92927ee31e5cf92bbd9915a69 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 2.8E-25 T 23-04-2016 DC74_RS08685 34fd99d92927ee31e5cf92bbd9915a69 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 2.8E-25 T 23-04-2016 DC74_RS08685 34fd99d92927ee31e5cf92bbd9915a69 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 2.8E-25 T 23-04-2016 DC74_RS08685 34fd99d92927ee31e5cf92bbd9915a69 406 PANTHER PTHR13789 15 401 8.4E-85 T 23-04-2016 DC74_RS08685 34fd99d92927ee31e5cf92bbd9915a69 406 SUPERFAMILY SSF54373 191 290 2.08E-28 T 23-04-2016 DC74_RS08685 34fd99d92927ee31e5cf92bbd9915a69 406 Gene3D G3DSA:3.30.9.10 172 314 1.1E-49 T 23-04-2016 DC74_RS08685 34fd99d92927ee31e5cf92bbd9915a69 406 PANTHER PTHR13789:SF192 15 401 8.4E-85 T 23-04-2016 DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 Gene3D G3DSA:3.40.50.2300 57 164 1.2E-34 T 23-04-2016 DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 Gene3D G3DSA:3.40.50.2300 165 328 4.7E-53 T 23-04-2016 DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 PANTHER PTHR30146 1 333 8.8E-145 T 23-04-2016 DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.7E-6 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.7E-6 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 Pfam PF13377 Periplasmic binding protein-like domain 168 327 1.1E-34 T 23-04-2016 DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 Gene3D G3DSA:1.10.260.40 2 56 3.9E-26 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 PANTHER PTHR30146:SF59 1 333 8.8E-145 T 23-04-2016 DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 SUPERFAMILY SSF53822 60 331 7.61E-70 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 SMART SM00354 1 70 1.5E-35 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 47 3.3E-20 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS14105 7619e12c79f4b263ca1d1a092c1fb749 333 SUPERFAMILY SSF47413 1 58 4.31E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS27510 328da19b211a43b1042951cb11e05759 345 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS27510 328da19b211a43b1042951cb11e05759 345 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 317 1.8E-29 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS27510 328da19b211a43b1042951cb11e05759 345 PANTHER PTHR24220 3 321 8.4E-169 T 23-04-2016 DC74_RS27510 328da19b211a43b1042951cb11e05759 345 SUPERFAMILY SSF52540 1 251 1.97E-74 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27510 328da19b211a43b1042951cb11e05759 345 Pfam PF00005 ABC transporter 29 179 2.6E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS27510 328da19b211a43b1042951cb11e05759 345 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 298 3.7E-18 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS27510 328da19b211a43b1042951cb11e05759 345 SMART SM00382 37 229 5.6E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS27510 328da19b211a43b1042951cb11e05759 345 PANTHER PTHR24220:SF336 3 321 8.4E-169 T 23-04-2016 DC74_RS27510 328da19b211a43b1042951cb11e05759 345 Gene3D G3DSA:3.40.50.300 2 253 2.1E-80 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12925 a8359153233533b3cb8f41996a471163 320 Gene3D G3DSA:1.10.287.90 41 124 1.3E-14 T 23-04-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 SUPERFAMILY SSF81464 26 124 1.8E-18 T 23-04-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 210 280 7.5E-17 T 23-04-2016 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 PANTHER PTHR22888:SF2 1 181 1.1E-99 T 23-04-2016 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 PANTHER PTHR22888:SF2 206 298 1.1E-99 T 23-04-2016 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 PANTHER PTHR22888 206 298 1.1E-99 T 23-04-2016 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 263 280 2.3E-13 T 23-04-2016 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 111 2.3E-13 T 23-04-2016 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 134 153 2.3E-13 T 23-04-2016 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 225 245 2.3E-13 T 23-04-2016 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 PRINTS PR01166 Cytochrome c oxidase subunit II signature 245 262 2.3E-13 T 23-04-2016 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 54 289 7.1E-45 T 23-04-2016 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 SUPERFAMILY SSF49503 131 157 5.67E-40 T 23-04-2016 IPR008972 Cupredoxin DC74_RS12925 a8359153233533b3cb8f41996a471163 320 SUPERFAMILY SSF49503 203 299 5.67E-40 T 23-04-2016 IPR008972 Cupredoxin DC74_RS12925 a8359153233533b3cb8f41996a471163 320 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 226 274 - T 23-04-2016 IPR001505 Copper centre Cu(A) GO:0005507 DC74_RS12925 a8359153233533b3cb8f41996a471163 320 Gene3D G3DSA:2.60.40.420 136 292 1.8E-39 T 23-04-2016 IPR008972 Cupredoxin DC74_RS12925 a8359153233533b3cb8f41996a471163 320 PANTHER PTHR22888 1 181 1.1E-99 T 23-04-2016 DC74_RS08175 b9b611f48d94635a9a5bc22bb7a392cc 820 SUPERFAMILY SSF51011 656 735 9.35E-19 T 23-04-2016 DC74_RS08175 b9b611f48d94635a9a5bc22bb7a392cc 820 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 467 474 - T 23-04-2016 IPR030458 Glycosyl hydrolases family 31, active site DC74_RS08175 b9b611f48d94635a9a5bc22bb7a392cc 820 SUPERFAMILY SSF74650 89 154 1.26E-13 T 23-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 DC74_RS08175 b9b611f48d94635a9a5bc22bb7a392cc 820 SUPERFAMILY SSF74650 182 302 1.26E-13 T 23-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 DC74_RS08175 b9b611f48d94635a9a5bc22bb7a392cc 820 PANTHER PTHR22762 162 742 3.4E-205 T 23-04-2016 DC74_RS08175 b9b611f48d94635a9a5bc22bb7a392cc 820 SUPERFAMILY SSF51445 307 654 2.28E-80 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS08175 b9b611f48d94635a9a5bc22bb7a392cc 820 Pfam PF01055 Glycosyl hydrolases family 31 299 740 1.7E-122 T 23-04-2016 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 DC74_RS08175 b9b611f48d94635a9a5bc22bb7a392cc 820 PANTHER PTHR22762:SF7 162 742 3.4E-205 T 23-04-2016 DC74_RS08175 b9b611f48d94635a9a5bc22bb7a392cc 820 Pfam PF13802 Galactose mutarotase-like 201 266 1.4E-9 T 23-04-2016 IPR025887 Glycoside hydrolase family 31, N-terminal domain DC74_RS27220 c367781518863304c184dd34442fb24d 474 Gene3D G3DSA:3.30.565.10 317 471 2.4E-38 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27220 c367781518863304c184dd34442fb24d 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 466 3.9E-20 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27220 c367781518863304c184dd34442fb24d 474 SMART SM00388 246 313 5.3E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS27220 c367781518863304c184dd34442fb24d 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 4.7E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS27220 c367781518863304c184dd34442fb24d 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 464 4.7E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS27220 c367781518863304c184dd34442fb24d 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 422 4.7E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS27220 c367781518863304c184dd34442fb24d 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 4.7E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS27220 c367781518863304c184dd34442fb24d 474 SMART SM00387 357 467 3.3E-33 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27220 c367781518863304c184dd34442fb24d 474 SUPERFAMILY SSF47384 229 312 5.89E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS27220 c367781518863304c184dd34442fb24d 474 Gene3D G3DSA:1.10.287.130 236 309 1.2E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS27220 c367781518863304c184dd34442fb24d 474 Pfam PF00672 HAMP domain 168 241 1.8E-14 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS27220 c367781518863304c184dd34442fb24d 474 SMART SM00304 187 245 1.2E-10 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS27220 c367781518863304c184dd34442fb24d 474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 312 5.7E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS27220 c367781518863304c184dd34442fb24d 474 SUPERFAMILY SSF55874 302 469 2.23E-37 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27220 c367781518863304c184dd34442fb24d 474 PANTHER PTHR24423 4 12 1.8E-67 T 23-04-2016 DC74_RS27220 c367781518863304c184dd34442fb24d 474 PANTHER PTHR24423 181 471 1.8E-67 T 23-04-2016 DC74_RS02555 fe4b007ceafc4af686f44ccff436fddb 199 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 32 158 1.9E-16 T 23-04-2016 DC74_RS02555 fe4b007ceafc4af686f44ccff436fddb 199 Gene3D G3DSA:3.40.50.720 1 198 1.6E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02555 fe4b007ceafc4af686f44ccff436fddb 199 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 55 66 3.4E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02555 fe4b007ceafc4af686f44ccff436fddb 199 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 3.4E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02555 fe4b007ceafc4af686f44ccff436fddb 199 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 145 3.4E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02555 fe4b007ceafc4af686f44ccff436fddb 199 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 162 3.4E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02555 fe4b007ceafc4af686f44ccff436fddb 199 SUPERFAMILY SSF51735 2 198 9.51E-32 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS28330 750f8e9a2a709e6580de42269ded984e 294 Gene3D G3DSA:1.10.3720.10 36 292 1.2E-50 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28330 750f8e9a2a709e6580de42269ded984e 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 281 5.6E-16 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28330 750f8e9a2a709e6580de42269ded984e 294 SUPERFAMILY SSF161098 32 287 1.87E-48 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28330 750f8e9a2a709e6580de42269ded984e 294 PANTHER PTHR30222 46 293 1.7E-62 T 23-04-2016 DC74_RS28330 750f8e9a2a709e6580de42269ded984e 294 PANTHER PTHR30222:SF1 46 293 1.7E-62 T 23-04-2016 DC74_RS29935 2b3ce01dac096b5208065d0e7532c9f2 305 PANTHER PTHR36492 25 297 4.5E-148 T 23-04-2016 DC74_RS29935 2b3ce01dac096b5208065d0e7532c9f2 305 Pfam PF00149 Calcineurin-like phosphoesterase 27 261 1.6E-15 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS29935 2b3ce01dac096b5208065d0e7532c9f2 305 Gene3D G3DSA:3.60.21.10 27 102 1.2E-21 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS29935 2b3ce01dac096b5208065d0e7532c9f2 305 Gene3D G3DSA:3.60.21.10 196 279 1.2E-21 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS29935 2b3ce01dac096b5208065d0e7532c9f2 305 PANTHER PTHR36492:SF1 25 297 4.5E-148 T 23-04-2016 DC74_RS29935 2b3ce01dac096b5208065d0e7532c9f2 305 SUPERFAMILY SSF56300 193 277 2.43E-26 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS29935 2b3ce01dac096b5208065d0e7532c9f2 305 SUPERFAMILY SSF56300 25 153 2.43E-26 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS38240 128df69b8a8a8750405b949ca12f03e9 145 Gene3D G3DSA:1.10.10.10 34 97 5.3E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38240 128df69b8a8a8750405b949ca12f03e9 145 Gene3D G3DSA:1.10.287.100 99 143 2.5E-12 T 23-04-2016 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 DC74_RS38240 128df69b8a8a8750405b949ca12f03e9 145 SUPERFAMILY SSF46785 13 143 2.0E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38240 128df69b8a8a8750405b949ca12f03e9 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 100 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS38240 128df69b8a8a8750405b949ca12f03e9 145 PANTHER PTHR39515 1 143 3.1E-22 T 23-04-2016 DC74_RS38240 128df69b8a8a8750405b949ca12f03e9 145 Pfam PF12802 MarR family 34 91 2.2E-10 T 23-04-2016 DC74_RS38240 128df69b8a8a8750405b949ca12f03e9 145 SMART SM00347 27 128 5.4E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS36300 7d000c01d1fbd1a3ff47bc7d24128359 214 Gene3D G3DSA:1.10.10.10 23 108 3.2E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36300 7d000c01d1fbd1a3ff47bc7d24128359 214 PANTHER PTHR33169 26 209 2.1E-19 T 23-04-2016 DC74_RS36300 7d000c01d1fbd1a3ff47bc7d24128359 214 SUPERFAMILY SSF46785 23 196 1.86E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36300 7d000c01d1fbd1a3ff47bc7d24128359 214 Pfam PF03551 Transcriptional regulator PadR-like family 27 103 1.1E-8 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS36300 7d000c01d1fbd1a3ff47bc7d24128359 214 PANTHER PTHR33169:SF4 26 209 2.1E-19 T 23-04-2016 DC74_RS30950 15e3e98711a169b9272849188c814512 197 Gene3D G3DSA:1.10.150.120 96 190 6.7E-31 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS30950 15e3e98711a169b9272849188c814512 197 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS30950 15e3e98711a169b9272849188c814512 197 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 27 74 7.4E-8 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS30950 15e3e98711a169b9272849188c814512 197 Gene3D G3DSA:3.10.20.30 23 95 3.2E-32 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS30950 15e3e98711a169b9272849188c814512 197 SUPERFAMILY SSF47741 105 190 4.58E-27 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS30950 15e3e98711a169b9272849188c814512 197 SUPERFAMILY SSF54292 23 108 8.78E-27 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS30950 15e3e98711a169b9272849188c814512 197 PANTHER PTHR11908 159 174 9.3E-40 T 23-04-2016 DC74_RS30950 15e3e98711a169b9272849188c814512 197 PANTHER PTHR11908 20 136 9.3E-40 T 23-04-2016 DC74_RS30950 15e3e98711a169b9272849188c814512 197 PANTHER PTHR11908:SF66 159 174 9.3E-40 T 23-04-2016 DC74_RS30950 15e3e98711a169b9272849188c814512 197 PANTHER PTHR11908:SF66 20 136 9.3E-40 T 23-04-2016 DC74_RS30950 15e3e98711a169b9272849188c814512 197 Pfam PF01799 [2Fe-2S] binding domain 94 184 1.4E-29 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS15695 ea6035335be768901410250709f9421c 630 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2 204 2.3E-30 T 23-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DC74_RS15695 ea6035335be768901410250709f9421c 630 Gene3D G3DSA:3.40.50.970 394 622 6.6E-57 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS15695 ea6035335be768901410250709f9421c 630 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 1 627 2.5E-265 T 23-04-2016 IPR030817 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22|UniPathway: UPA00076 DC74_RS15695 ea6035335be768901410250709f9421c 630 SUPERFAMILY SSF52518 402 616 3.04E-49 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS15695 ea6035335be768901410250709f9421c 630 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 423 581 1.8E-39 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS15695 ea6035335be768901410250709f9421c 630 PANTHER PTHR18968:SF9 1 616 2.7E-276 T 23-04-2016 IPR030817 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22|UniPathway: UPA00076 DC74_RS15695 ea6035335be768901410250709f9421c 630 PANTHER PTHR18968 1 616 2.7E-276 T 23-04-2016 DC74_RS15695 ea6035335be768901410250709f9421c 630 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 226 359 4.1E-31 T 23-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DC74_RS15695 ea6035335be768901410250709f9421c 630 SUPERFAMILY SSF52518 2 217 3.3E-28 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS15695 ea6035335be768901410250709f9421c 630 SUPERFAMILY SSF52467 192 373 2.5E-42 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS15695 ea6035335be768901410250709f9421c 630 Gene3D G3DSA:3.40.50.970 1 216 3.5E-56 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS15695 ea6035335be768901410250709f9421c 630 Gene3D G3DSA:3.40.50.1220 217 369 9.8E-41 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS34070 7f589f6758958228940a47ee72bb798c 446 Pfam PF00083 Sugar (and other) transporter 27 445 1.2E-31 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS34070 7f589f6758958228940a47ee72bb798c 446 Gene3D G3DSA:1.20.1250.20 258 442 5.4E-24 T 23-04-2016 DC74_RS34070 7f589f6758958228940a47ee72bb798c 446 Gene3D G3DSA:1.20.1250.20 23 226 3.4E-23 T 23-04-2016 DC74_RS34070 7f589f6758958228940a47ee72bb798c 446 PANTHER PTHR23508 21 445 1.0E-201 T 23-04-2016 DC74_RS34070 7f589f6758958228940a47ee72bb798c 446 ProSitePatterns PS00217 Sugar transport proteins signature 2. 136 161 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS34070 7f589f6758958228940a47ee72bb798c 446 PANTHER PTHR23508:SF4 21 445 1.0E-201 T 23-04-2016 DC74_RS34070 7f589f6758958228940a47ee72bb798c 446 ProSitePatterns PS00216 Sugar transport proteins signature 1. 314 331 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS34070 7f589f6758958228940a47ee72bb798c 446 SUPERFAMILY SSF103473 18 441 6.67E-70 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS16365 3f28c2f4f713de5840d9365e05b1bd90 250 SUPERFAMILY SSF56281 1 249 1.7E-54 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS16365 3f28c2f4f713de5840d9365e05b1bd90 250 Pfam PF12706 Beta-lactamase superfamily domain 30 218 2.0E-22 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS16365 3f28c2f4f713de5840d9365e05b1bd90 250 Gene3D G3DSA:3.60.15.10 1 249 1.5E-59 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS16365 3f28c2f4f713de5840d9365e05b1bd90 250 SMART SM00849 18 199 0.0035 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS16365 3f28c2f4f713de5840d9365e05b1bd90 250 PANTHER PTHR12553 1 242 1.2E-54 T 23-04-2016 DC74_RS12005 400960c2d941b5bfe95053901f3490e6 500 PANTHER PTHR38133 47 212 7.3E-63 T 23-04-2016 DC74_RS12005 400960c2d941b5bfe95053901f3490e6 500 PANTHER PTHR38133 246 500 7.3E-63 T 23-04-2016 DC74_RS12005 400960c2d941b5bfe95053901f3490e6 500 PANTHER PTHR38133:SF1 47 212 7.3E-63 T 23-04-2016 DC74_RS12005 400960c2d941b5bfe95053901f3490e6 500 PANTHER PTHR38133:SF1 246 500 7.3E-63 T 23-04-2016 DC74_RS12005 400960c2d941b5bfe95053901f3490e6 500 Pfam PF04434 SWIM zinc finger 156 178 2.7E-6 T 23-04-2016 IPR007527 Zinc finger, SWIM-type GO:0008270 DC74_RS04740 ab79aeae1413b3470616501c9efe71a6 323 Pfam PF07859 alpha/beta hydrolase fold 83 292 9.7E-65 T 23-04-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 DC74_RS04740 ab79aeae1413b3470616501c9efe71a6 323 SUPERFAMILY SSF53474 45 318 5.99E-68 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS04740 ab79aeae1413b3470616501c9efe71a6 323 Gene3D G3DSA:3.40.50.1820 11 318 1.3E-86 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS04740 ab79aeae1413b3470616501c9efe71a6 323 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 83 99 - T 23-04-2016 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 DC74_RS04740 ab79aeae1413b3470616501c9efe71a6 323 PANTHER PTHR23024:SF128 64 321 1.0E-105 T 23-04-2016 DC74_RS04740 ab79aeae1413b3470616501c9efe71a6 323 PANTHER PTHR23024 64 321 1.0E-105 T 23-04-2016 DC74_RS22845 4a09c6359a1f9788bace39b5fe119354 426 Gene3D G3DSA:3.40.47.10 1 277 1.0E-31 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22845 4a09c6359a1f9788bace39b5fe119354 426 SUPERFAMILY SSF53901 238 422 1.08E-28 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22845 4a09c6359a1f9788bace39b5fe119354 426 PANTHER PTHR11712:SF279 141 384 2.4E-20 T 23-04-2016 DC74_RS22845 4a09c6359a1f9788bace39b5fe119354 426 PANTHER PTHR11712:SF279 1 115 2.4E-20 T 23-04-2016 DC74_RS22845 4a09c6359a1f9788bace39b5fe119354 426 SMART SM00825 Beta-ketoacyl synthase 1 424 5.2E-5 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS22845 4a09c6359a1f9788bace39b5fe119354 426 SUPERFAMILY SSF53901 1 270 2.3E-32 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22845 4a09c6359a1f9788bace39b5fe119354 426 Gene3D G3DSA:3.40.47.10 293 422 4.7E-18 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22845 4a09c6359a1f9788bace39b5fe119354 426 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 265 4.4E-19 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS22845 4a09c6359a1f9788bace39b5fe119354 426 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 381 6.9E-11 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS22845 4a09c6359a1f9788bace39b5fe119354 426 PANTHER PTHR11712 1 115 2.4E-20 T 23-04-2016 DC74_RS22845 4a09c6359a1f9788bace39b5fe119354 426 PANTHER PTHR11712 141 384 2.4E-20 T 23-04-2016 DC74_RS00565 d731be4701a56ac0b47e961403800fda 376 PANTHER PTHR36195 48 367 3.4E-48 T 23-04-2016 DC74_RS00565 d731be4701a56ac0b47e961403800fda 376 PANTHER PTHR36195:SF3 48 367 3.4E-48 T 23-04-2016 DC74_RS00565 d731be4701a56ac0b47e961403800fda 376 Gene3D G3DSA:2.40.180.10 24 361 2.2E-30 T 23-04-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS00565 d731be4701a56ac0b47e961403800fda 376 SUPERFAMILY SSF56634 33 366 1.02E-46 T 23-04-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS33750 3f20e5146a16280eb13641cdbaf93cc4 332 PANTHER PTHR11695 16 330 2.0E-112 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS33750 3f20e5146a16280eb13641cdbaf93cc4 332 Pfam PF00107 Zinc-binding dehydrogenase 153 270 4.4E-30 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS33750 3f20e5146a16280eb13641cdbaf93cc4 332 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 142 163 - T 23-04-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 DC74_RS33750 3f20e5146a16280eb13641cdbaf93cc4 332 SUPERFAMILY SSF50129 2 142 9.13E-35 T 23-04-2016 IPR011032 GroES-like DC74_RS33750 3f20e5146a16280eb13641cdbaf93cc4 332 SMART SM00829 13 324 2.5E-36 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS33750 3f20e5146a16280eb13641cdbaf93cc4 332 Gene3D G3DSA:3.90.180.10 2 147 1.4E-41 T 23-04-2016 IPR011032 GroES-like DC74_RS33750 3f20e5146a16280eb13641cdbaf93cc4 332 PANTHER PTHR11695:SF31 16 330 2.0E-112 T 23-04-2016 DC74_RS33750 3f20e5146a16280eb13641cdbaf93cc4 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 4.1E-8 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS33750 3f20e5146a16280eb13641cdbaf93cc4 332 Gene3D G3DSA:3.40.50.720 148 263 3.5E-31 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS33750 3f20e5146a16280eb13641cdbaf93cc4 332 SUPERFAMILY SSF51735 114 269 1.72E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26775 5864378018bf27ff11057d8af755c2aa 315 SUPERFAMILY SSF47240 42 230 2.06E-10 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS26775 5864378018bf27ff11057d8af755c2aa 315 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 24 298 2.9E-96 T 23-04-2016 IPR025859 P-aminobenzoate N-oxygenase AurF DC74_RS20820 96fa3d747db561d6bc402758b9315e5b 96 PANTHER PTHR21011 1 92 4.2E-27 T 23-04-2016 DC74_RS20820 96fa3d747db561d6bc402758b9315e5b 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 92 2.3E-25 T 23-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS20820 96fa3d747db561d6bc402758b9315e5b 96 Gene3D G3DSA:3.30.70.60 1 94 3.5E-34 T 23-04-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 DC74_RS20820 96fa3d747db561d6bc402758b9315e5b 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 23-04-2016 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS20820 96fa3d747db561d6bc402758b9315e5b 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 21.969 T 23-04-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS20820 96fa3d747db561d6bc402758b9315e5b 96 Pfam PF01250 Ribosomal protein S6 3 92 6.9E-28 T 23-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS20820 96fa3d747db561d6bc402758b9315e5b 96 SUPERFAMILY SSF54995 1 94 4.84E-32 T 23-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 PANTHER PTHR19959:SF135 448 702 8.9E-24 T 23-04-2016 DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 SUPERFAMILY SSF48452 444 547 5.82E-10 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 SUPERFAMILY SSF48452 600 695 6.01E-8 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 SUPERFAMILY SSF48452 521 561 6.01E-8 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 Gene3D G3DSA:1.25.40.10 446 556 1.6E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 Gene3D G3DSA:1.25.40.10 607 688 1.6E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 Pfam PF13374 Tetratricopeptide repeat 660 692 1.0E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 Gene3D G3DSA:3.40.50.300 59 194 4.2E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 Pfam PF13424 Tetratricopeptide repeat 446 512 5.7E-8 T 23-04-2016 DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 PANTHER PTHR19959 448 702 8.9E-24 T 23-04-2016 DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 SUPERFAMILY SSF52540 62 269 1.81E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 PRINTS PR00364 Disease resistance protein signature 77 92 1.9E-5 T 23-04-2016 DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 PRINTS PR00364 Disease resistance protein signature 155 169 1.9E-5 T 23-04-2016 DC74_RS31660 80ee2960dc2aad5973964375eaef66e9 712 PRINTS PR00364 Disease resistance protein signature 240 254 1.9E-5 T 23-04-2016 DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 154 5.1E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 62 73 5.1E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 115 123 5.1E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 122 150 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 PANTHER PTHR24322 135 166 5.9E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 PANTHER PTHR24322 2 119 5.9E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 Pfam PF00106 short chain dehydrogenase 1 176 1.1E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 109 125 1.4E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 154 1.4E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 62 73 1.4E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 173 1.4E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 Gene3D G3DSA:3.40.50.720 1 252 2.0E-63 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS21265 fe1125b25dcf20d589e76d95d6961dec 259 SUPERFAMILY SSF51735 1 253 2.5E-57 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS33015 d332c7bd972b09b45dbf4bbe810330b6 380 Gene3D G3DSA:1.20.140.10 219 380 1.8E-57 T 23-04-2016 DC74_RS33015 d332c7bd972b09b45dbf4bbe810330b6 380 Gene3D G3DSA:1.10.540.10 6 120 1.4E-36 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS33015 d332c7bd972b09b45dbf4bbe810330b6 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 1.5E-34 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS33015 d332c7bd972b09b45dbf4bbe810330b6 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 1.8E-26 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS33015 d332c7bd972b09b45dbf4bbe810330b6 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 379 1.0E-42 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS33015 d332c7bd972b09b45dbf4bbe810330b6 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS33015 d332c7bd972b09b45dbf4bbe810330b6 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS33015 d332c7bd972b09b45dbf4bbe810330b6 380 Gene3D G3DSA:2.40.110.10 123 218 1.9E-40 T 23-04-2016 DC74_RS33015 d332c7bd972b09b45dbf4bbe810330b6 380 PANTHER PTHR10909 3 380 2.0E-238 T 23-04-2016 DC74_RS33015 d332c7bd972b09b45dbf4bbe810330b6 380 SUPERFAMILY SSF56645 5 242 6.54E-84 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS33015 d332c7bd972b09b45dbf4bbe810330b6 380 PANTHER PTHR10909:SF190 3 380 2.0E-238 T 23-04-2016 DC74_RS33015 d332c7bd972b09b45dbf4bbe810330b6 380 SUPERFAMILY SSF47203 229 380 2.99E-46 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS28230 91341f9ec27c5357c3ec848651b501e0 356 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS28230 91341f9ec27c5357c3ec848651b501e0 356 Gene3D G3DSA:3.40.50.300 5 245 3.9E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28230 91341f9ec27c5357c3ec848651b501e0 356 PANTHER PTHR24220:SF123 14 289 3.0E-110 T 23-04-2016 DC74_RS28230 91341f9ec27c5357c3ec848651b501e0 356 SUPERFAMILY SSF52540 12 254 2.49E-77 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28230 91341f9ec27c5357c3ec848651b501e0 356 Pfam PF00005 ABC transporter 31 173 6.9E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS28230 91341f9ec27c5357c3ec848651b501e0 356 Pfam PF08402 TOBE domain 281 351 1.6E-11 T 23-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 DC74_RS28230 91341f9ec27c5357c3ec848651b501e0 356 PANTHER PTHR24220 14 289 3.0E-110 T 23-04-2016 DC74_RS28230 91341f9ec27c5357c3ec848651b501e0 356 SMART SM00382 40 223 8.5E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS28230 91341f9ec27c5357c3ec848651b501e0 356 SUPERFAMILY SSF50331 250 352 7.37E-10 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal DC74_RS38735 d0366041720e79652308461270dad677 352 Gene3D G3DSA:3.90.1150.10 240 349 7.7E-16 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS38735 d0366041720e79652308461270dad677 352 PANTHER PTHR30244:SF16 6 352 6.4E-111 T 23-04-2016 DC74_RS38735 d0366041720e79652308461270dad677 352 Gene3D G3DSA:3.40.640.10 6 233 4.8E-78 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS38735 d0366041720e79652308461270dad677 352 SUPERFAMILY SSF53383 6 350 1.65E-99 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS38735 d0366041720e79652308461270dad677 352 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 344 5.4E-96 T 23-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase DC74_RS38735 d0366041720e79652308461270dad677 352 PANTHER PTHR30244 6 352 6.4E-111 T 23-04-2016 DC74_RS38735 d0366041720e79652308461270dad677 352 PIRSF PIRSF000390 4 351 7.9E-93 T 23-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase DC74_RS17650 ee094524ef156f8be77fc843d05000b3 551 Pfam PF00905 Penicillin binding protein transpeptidase domain 276 548 2.9E-37 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS17650 ee094524ef156f8be77fc843d05000b3 551 PANTHER PTHR30627:SF4 204 550 1.2E-126 T 23-04-2016 DC74_RS17650 ee094524ef156f8be77fc843d05000b3 551 PANTHER PTHR30627 204 550 1.2E-126 T 23-04-2016 DC74_RS17650 ee094524ef156f8be77fc843d05000b3 551 Gene3D G3DSA:3.40.710.10 256 549 2.4E-54 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS17650 ee094524ef156f8be77fc843d05000b3 551 SUPERFAMILY SSF56601 250 549 1.94E-54 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS17650 ee094524ef156f8be77fc843d05000b3 551 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 64 170 5.4E-6 T 23-04-2016 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 DC74_RS32220 f1701b9833c2db8840c773831957638a 399 Pfam PF02687 FtsX-like permease family 280 392 8.0E-23 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS32220 f1701b9833c2db8840c773831957638a 399 Pfam PF12704 MacB-like periplasmic core domain 32 197 3.1E-16 T 23-04-2016 IPR025857 MacB-like periplasmic core domain DC74_RS32220 f1701b9833c2db8840c773831957638a 399 PANTHER PTHR30572 14 399 1.3E-51 T 23-04-2016 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 Gene3D G3DSA:3.30.413.10 422 560 3.0E-37 T 23-04-2016 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 PANTHER PTHR32439 3 564 5.6E-207 T 23-04-2016 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 SUPERFAMILY SSF56014 421 562 1.06E-36 T 23-04-2016 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 PRINTS PR00397 Sirohaem Fe-binding site signature 425 443 1.4E-9 T 23-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 PRINTS PR00397 Sirohaem Fe-binding site signature 470 488 1.4E-9 T 23-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 470 486 - T 23-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 Gene3D G3DSA:3.30.413.10 172 324 3.2E-44 T 23-04-2016 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 SUPERFAMILY SSF55124 304 436 1.8E-19 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 101 162 7.6E-22 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 348 413 3.6E-13 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 SUPERFAMILY SSF56014 172 333 4.97E-47 T 23-04-2016 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 Gene3D G3DSA:3.90.480.10 101 169 5.2E-48 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 Gene3D G3DSA:3.90.480.10 341 416 5.2E-48 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 SUPERFAMILY SSF55124 21 171 2.29E-40 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 172 326 1.9E-40 T 23-04-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 425 557 8.0E-10 T 23-04-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS30860 6d21394654dba5c614871a38b6bc2dbb 564 PANTHER PTHR32439:SF0 3 564 5.6E-207 T 23-04-2016 DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 Gene3D G3DSA:1.10.10.10 165 223 7.5E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 PANTHER PTHR26402 13 223 4.1E-73 T 23-04-2016 DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 SUPERFAMILY SSF52172 12 142 1.1E-29 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 PANTHER PTHR26402:SF151 13 223 4.1E-73 T 23-04-2016 DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 Gene3D G3DSA:3.40.50.2300 11 164 8.5E-37 T 23-04-2016 DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 179 206 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 Pfam PF00072 Response regulator receiver domain 15 127 8.9E-24 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 219 3.6E-18 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 SUPERFAMILY SSF46894 153 223 2.01E-21 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 SMART SM00421 162 219 2.3E-26 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 207 3.9E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 179 3.9E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 195 3.9E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01195 833bbfe69eecf3e0c07085a132f71137 228 SMART SM00448 13 126 2.1E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 SUPERFAMILY SSF49785 392 566 2.98E-27 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 SMART SM00939 351 585 8.5E-17 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 Pfam PF00005 ABC transporter 646 786 2.5E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 Gene3D G3DSA:3.40.50.300 622 845 3.7E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 89 323 1.1E-19 T 23-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 SUPERFAMILY SSF52540 616 847 4.52E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 454 562 2.0E-13 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 Gene3D G3DSA:3.40.50.1820 252 359 1.6E-55 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 Gene3D G3DSA:3.40.50.1820 54 194 1.6E-55 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 Gene3D G3DSA:2.60.120.260 385 564 6.6E-24 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 PANTHER PTHR24220:SF427 628 847 2.7E-94 T 23-04-2016 DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 PANTHER PTHR24220 628 847 2.7E-94 T 23-04-2016 DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 SMART SM00382 654 834 2.9E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 ProSitePatterns PS00211 ABC transporters family signature. 758 772 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 SUPERFAMILY SSF53474 255 363 3.06E-49 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS15680 b92d2f6ec69a1852ed5e09ab8d99f6c1 931 SUPERFAMILY SSF53474 54 190 3.06E-49 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 56 394 4.5E-112 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 315 332 - T 23-04-2016 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 Gene3D G3DSA:3.40.50.1700 419 608 2.9E-17 T 23-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 PANTHER PTHR30480:SF5 86 610 4.7E-217 T 23-04-2016 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 PANTHER PTHR30480:SF5 41 70 4.7E-217 T 23-04-2016 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 Gene3D G3DSA:3.20.20.300 61 418 7.6E-111 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 PANTHER PTHR30480 86 610 4.7E-217 T 23-04-2016 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 PANTHER PTHR30480 41 70 4.7E-217 T 23-04-2016 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 433 610 1.4E-14 T 23-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 SUPERFAMILY SSF52279 433 610 1.11E-14 T 23-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 SUPERFAMILY SSF51445 39 429 1.37E-102 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 PRINTS PR00133 Glycosyl hydrolase family 3 signature 160 179 7.1E-7 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 PRINTS PR00133 Glycosyl hydrolase family 3 signature 134 150 7.1E-7 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 PRINTS PR00133 Glycosyl hydrolase family 3 signature 238 254 7.1E-7 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 PRINTS PR00133 Glycosyl hydrolase family 3 signature 315 333 7.1E-7 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS15800 d7a51521aa91167c259239918e8c4728 610 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 32 4.9E-4 T 23-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal DC74_RS16220 adef8b04a5b2a6d948935b4325c2866c 285 PANTHER PTHR11820 1 282 9.7E-161 T 23-04-2016 DC74_RS16220 adef8b04a5b2a6d948935b4325c2866c 285 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 282 3.5E-68 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS16220 adef8b04a5b2a6d948935b4325c2866c 285 Gene3D G3DSA:3.90.850.10 68 282 1.8E-85 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS16220 adef8b04a5b2a6d948935b4325c2866c 285 PANTHER PTHR11820:SF71 1 282 9.7E-161 T 23-04-2016 DC74_RS16220 adef8b04a5b2a6d948935b4325c2866c 285 SUPERFAMILY SSF56529 65 282 3.79E-75 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS01225 003896baf4a81da089ee7cc41207aa6f 220 Gene3D G3DSA:3.40.50.2300 2 121 1.3E-33 T 23-04-2016 DC74_RS01225 003896baf4a81da089ee7cc41207aa6f 220 SUPERFAMILY SSF52172 2 121 1.27E-33 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS01225 003896baf4a81da089ee7cc41207aa6f 220 PANTHER PTHR26402 3 219 1.6E-67 T 23-04-2016 DC74_RS01225 003896baf4a81da089ee7cc41207aa6f 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 218 7.7E-21 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS01225 003896baf4a81da089ee7cc41207aa6f 220 SMART SM00862 144 219 3.1E-20 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS01225 003896baf4a81da089ee7cc41207aa6f 220 Gene3D G3DSA:1.10.10.10 122 219 3.7E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01225 003896baf4a81da089ee7cc41207aa6f 220 SMART SM00448 3 113 5.7E-35 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS01225 003896baf4a81da089ee7cc41207aa6f 220 PANTHER PTHR26402:SF50 3 219 1.6E-67 T 23-04-2016 DC74_RS01225 003896baf4a81da089ee7cc41207aa6f 220 SUPERFAMILY SSF46894 122 219 3.4E-23 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS01225 003896baf4a81da089ee7cc41207aa6f 220 Pfam PF00072 Response regulator receiver domain 5 113 7.9E-22 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 Pfam PF09371 Tex-like protein N-terminal domain 20 203 1.6E-65 T 23-04-2016 IPR018974 Tex-like protein, N-terminal DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 Gene3D G3DSA:1.10.3500.10 463 510 3.9E-101 T 23-04-2016 IPR023323 Tex-like domain DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 Gene3D G3DSA:1.10.3500.10 121 333 3.9E-101 T 23-04-2016 IPR023323 Tex-like domain DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 Pfam PF12836 Helix-hairpin-helix motif 503 567 2.3E-27 T 23-04-2016 DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 Gene3D G3DSA:3.30.420.140 337 462 6.7E-51 T 23-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 Gene3D G3DSA:2.40.50.140 645 732 5.4E-26 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 SMART SM00732 337 436 5.0E-38 T 23-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 SUPERFAMILY SSF50249 649 734 1.57E-23 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 SUPERFAMILY SSF47781 482 570 6.45E-27 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 Pfam PF16921 Tex protein YqgF-like domain 338 463 2.8E-51 T 23-04-2016 IPR032639 Tex protein, YqgF-like domain DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 SUPERFAMILY SSF53098 333 481 6.75E-50 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 Gene3D G3DSA:1.10.150.310 511 642 1.3E-43 T 23-04-2016 IPR023097 Tex RuvX-like domain DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 SMART SM00316 661 732 1.2E-24 T 23-04-2016 IPR022967 RNA-binding domain, S1 DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 PANTHER PTHR10724:SF1 15 802 0.0 T 23-04-2016 DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 PANTHER PTHR10724 15 802 0.0 T 23-04-2016 DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 Pfam PF00575 S1 RNA binding domain 662 732 6.0E-18 T 23-04-2016 IPR003029 S1 domain GO:0003676 DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 SUPERFAMILY SSF47781 572 644 4.45E-19 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 Gene3D G3DSA:1.10.10.650 15 120 4.3E-42 T 23-04-2016 IPR023319 Tex-like protein, HTH domain DC74_RS33125 fa9273269d062ed113a9755d6e8c43b8 810 SUPERFAMILY SSF158832 15 332 8.5E-112 T 23-04-2016 DC74_RS08905 deb26ee8f6990ab5842907359566074d 262 Gene3D G3DSA:3.40.50.620 3 261 1.3E-86 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS08905 deb26ee8f6990ab5842907359566074d 262 SMART SM00893 24 215 8.2E-57 T 23-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 DC74_RS08905 deb26ee8f6990ab5842907359566074d 262 SUPERFAMILY SSF52402 3 258 3.43E-72 T 23-04-2016 DC74_RS08905 deb26ee8f6990ab5842907359566074d 262 PANTHER PTHR21294:SF0 1 256 1.2E-93 T 23-04-2016 DC74_RS08905 deb26ee8f6990ab5842907359566074d 262 PIRSF PIRSF000090 3 262 6.2E-83 T 23-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 DC74_RS08905 deb26ee8f6990ab5842907359566074d 262 Pfam PF01012 Electron transfer flavoprotein domain 25 210 9.9E-46 T 23-04-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 DC74_RS08905 deb26ee8f6990ab5842907359566074d 262 PANTHER PTHR21294 1 256 1.2E-93 T 23-04-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 DC74_RS04800 0d30425b708a346edde78d86e62da547 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 79 1.2E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS04800 0d30425b708a346edde78d86e62da547 238 SUPERFAMILY SSF48008 85 222 7.06E-23 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS04800 0d30425b708a346edde78d86e62da547 238 Pfam PF07729 FCD domain 89 209 7.0E-19 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS04800 0d30425b708a346edde78d86e62da547 238 SMART SM00895 89 214 3.5E-13 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS04800 0d30425b708a346edde78d86e62da547 238 Gene3D G3DSA:1.20.120.530 83 224 3.5E-24 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS04800 0d30425b708a346edde78d86e62da547 238 SUPERFAMILY SSF46785 13 103 2.53E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04800 0d30425b708a346edde78d86e62da547 238 SMART SM00345 21 79 8.4E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS04800 0d30425b708a346edde78d86e62da547 238 PANTHER PTHR11751 15 105 7.1E-14 T 23-04-2016 DC74_RS04800 0d30425b708a346edde78d86e62da547 238 Gene3D G3DSA:1.10.10.10 13 79 5.2E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14900 e1bfc495cebb091c45baf3ac01221d2c 120 PANTHER PTHR36221 9 118 4.5E-22 T 23-04-2016 DC74_RS14900 e1bfc495cebb091c45baf3ac01221d2c 120 Pfam PF05331 Protein of unknown function (DUF742) 10 118 2.4E-27 T 23-04-2016 IPR007995 Protein of unknown function DUF742 DC74_RS14900 e1bfc495cebb091c45baf3ac01221d2c 120 Gene3D G3DSA:1.10.10.10 52 92 1.3E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PANTHER PTHR22773 511 611 3.6E-180 T 23-04-2016 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PANTHER PTHR22773:SF50 1 481 3.6E-180 T 23-04-2016 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PANTHER PTHR22773:SF50 511 611 3.6E-180 T 23-04-2016 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PANTHER PTHR22773 1 481 3.6E-180 T 23-04-2016 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 68 119 4.6E-10 T 23-04-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 Pfam PF00361 Proton-conducting membrane transporter 133 406 1.1E-75 T 23-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 83 103 1.1E-8 T 23-04-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 261 283 1.1E-8 T 23-04-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 598 624 1.1E-8 T 23-04-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 356 378 1.1E-8 T 23-04-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 5 653 8.1E-136 T 23-04-2016 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 156 177 2.5E-48 T 23-04-2016 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 2.5E-48 T 23-04-2016 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 2.5E-48 T 23-04-2016 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 426 445 2.5E-48 T 23-04-2016 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 243 269 2.5E-48 T 23-04-2016 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 81 106 2.5E-48 T 23-04-2016 DC74_RS18900 d671b63c3c2fd5542d050a1d692fff28 665 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 109 129 2.5E-48 T 23-04-2016 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PANTHER PTHR10422:SF6 17 563 4.2E-290 T 23-04-2016 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 31 56 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 390 409 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 105 129 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 78 101 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 362 380 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 209 228 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 327 348 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 440 461 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 238 259 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 180 198 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 259 280 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 305 320 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PRINTS PR01165 Cytochrome c oxidase subunit I signature 148 160 3.3E-106 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 SUPERFAMILY SSF81442 29 539 4.71E-178 T 23-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 PANTHER PTHR10422 17 563 4.2E-290 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 32 536 6.6E-213 T 23-04-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 Gene3D G3DSA:1.20.210.10 26 549 8.0E-195 T 23-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 261 315 - T 23-04-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS03870 bcc9e8794f8141c84ad752c865b57875 563 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 41 484 1.6E-147 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS38480 9a82ae68c750541e2de1588a6255f64f 551 Gene3D G3DSA:3.40.190.10 218 319 3.3E-25 T 23-04-2016 DC74_RS38480 9a82ae68c750541e2de1588a6255f64f 551 PIRSF PIRSF002741 16 547 7.3E-69 T 23-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DC74_RS38480 9a82ae68c750541e2de1588a6255f64f 551 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 104 469 1.2E-62 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain DC74_RS38480 9a82ae68c750541e2de1588a6255f64f 551 PANTHER PTHR30290 9 546 9.7E-90 T 23-04-2016 DC74_RS38480 9a82ae68c750541e2de1588a6255f64f 551 Gene3D G3DSA:3.90.76.10 70 207 1.3E-27 T 23-04-2016 DC74_RS38480 9a82ae68c750541e2de1588a6255f64f 551 Gene3D G3DSA:3.10.105.10 320 516 3.6E-32 T 23-04-2016 DC74_RS38480 9a82ae68c750541e2de1588a6255f64f 551 SUPERFAMILY SSF53850 63 541 1.1E-98 T 23-04-2016 DC74_RS32580 a6d7369698cb0042b93e9af018fd6344 388 Pfam PF00931 NB-ARC domain 62 310 1.6E-6 T 23-04-2016 IPR002182 NB-ARC GO:0043531 DC74_RS32580 a6d7369698cb0042b93e9af018fd6344 388 SUPERFAMILY SSF52540 44 307 2.2E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32580 a6d7369698cb0042b93e9af018fd6344 388 Gene3D G3DSA:3.40.50.300 55 175 6.7E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32580 a6d7369698cb0042b93e9af018fd6344 388 PANTHER PTHR22845 33 374 2.5E-45 T 23-04-2016 DC74_RS32580 a6d7369698cb0042b93e9af018fd6344 388 PANTHER PTHR22845:SF4 33 374 2.5E-45 T 23-04-2016 DC74_RS03800 00516df2a5bc7eefb6c47571b55dbf7b 393 PANTHER PTHR34184:SF4 1 377 1.0E-93 T 23-04-2016 DC74_RS03800 00516df2a5bc7eefb6c47571b55dbf7b 393 Pfam PF03773 Predicted permease 6 316 1.0E-75 T 23-04-2016 IPR005524 Predicted permease DUF318 DC74_RS03800 00516df2a5bc7eefb6c47571b55dbf7b 393 PANTHER PTHR34184 1 377 1.0E-93 T 23-04-2016 DC74_RS22550 d419e0c205c3d5c6d6d90dad4a8db6f9 365 Pfam PF01212 Beta-eliminating lyase 35 269 4.9E-26 T 23-04-2016 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 DC74_RS22550 d419e0c205c3d5c6d6d90dad4a8db6f9 365 PANTHER PTHR10289 35 296 2.4E-94 T 23-04-2016 DC74_RS22550 d419e0c205c3d5c6d6d90dad4a8db6f9 365 SUPERFAMILY SSF53383 29 299 3.8E-57 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS22550 d419e0c205c3d5c6d6d90dad4a8db6f9 365 Gene3D G3DSA:3.40.640.10 11 248 1.2E-29 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS22550 d419e0c205c3d5c6d6d90dad4a8db6f9 365 PANTHER PTHR10289:SF7 35 296 2.4E-94 T 23-04-2016 DC74_RS07625 2832ec021763f0804fecd0ebb66a820d 431 Pfam PF07730 Histidine kinase 225 290 1.0E-14 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS07625 2832ec021763f0804fecd0ebb66a820d 431 PANTHER PTHR24421:SF26 153 430 7.6E-49 T 23-04-2016 DC74_RS07625 2832ec021763f0804fecd0ebb66a820d 431 SUPERFAMILY SSF55874 308 426 4.21E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS07625 2832ec021763f0804fecd0ebb66a820d 431 PANTHER PTHR24421 153 430 7.6E-49 T 23-04-2016 DC74_RS22115 ccdc1bb606360775b865af744ca6dba1 390 PANTHER PTHR13696:SF64 74 365 1.9E-57 T 23-04-2016 DC74_RS22115 ccdc1bb606360775b865af744ca6dba1 390 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 23 360 2.1E-94 T 23-04-2016 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like DC74_RS22115 ccdc1bb606360775b865af744ca6dba1 390 PANTHER PTHR13696 74 365 1.9E-57 T 23-04-2016 DC74_RS22115 ccdc1bb606360775b865af744ca6dba1 390 Gene3D G3DSA:3.40.50.300 133 343 7.1E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22115 ccdc1bb606360775b865af744ca6dba1 390 SUPERFAMILY SSF52540 133 343 4.85E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22115 ccdc1bb606360775b865af744ca6dba1 390 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 136 290 1.4E-10 T 23-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DC74_RS08135 435274e5fafcda4c2857aca0b22591e6 202 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 85 3.8E-15 T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS08135 435274e5fafcda4c2857aca0b22591e6 202 PANTHER PTHR14269 5 195 2.2E-32 T 23-04-2016 DC74_RS08135 435274e5fafcda4c2857aca0b22591e6 202 PIRSF PIRSF000847 11 202 1.1E-43 T 23-04-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 DC74_RS08135 435274e5fafcda4c2857aca0b22591e6 202 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS18070 65a807be498aa0080a6614a839268c18 426 PANTHER PTHR24423 64 87 1.7E-43 T 23-04-2016 DC74_RS18070 65a807be498aa0080a6614a839268c18 426 PANTHER PTHR24423 140 415 1.7E-43 T 23-04-2016 DC74_RS18070 65a807be498aa0080a6614a839268c18 426 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 409 6.2E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS18070 65a807be498aa0080a6614a839268c18 426 SMART SM00388 208 266 2.3E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS18070 65a807be498aa0080a6614a839268c18 426 Gene3D G3DSA:3.30.565.10 253 413 1.3E-22 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS18070 65a807be498aa0080a6614a839268c18 426 SMART SM00387 304 412 5.6E-16 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS18070 65a807be498aa0080a6614a839268c18 426 Pfam PF00672 HAMP domain 127 203 1.7E-11 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS18070 65a807be498aa0080a6614a839268c18 426 SMART SM00304 146 207 8.7E-9 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS18070 65a807be498aa0080a6614a839268c18 426 SUPERFAMILY SSF47384 192 266 2.35E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS18070 65a807be498aa0080a6614a839268c18 426 SUPERFAMILY SSF55874 255 414 7.2E-25 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS18070 65a807be498aa0080a6614a839268c18 426 Pfam PF00512 His Kinase A (phospho-acceptor) domain 209 266 3.8E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS18070 65a807be498aa0080a6614a839268c18 426 Gene3D G3DSA:1.10.287.130 198 252 1.9E-14 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 PANTHER PTHR10395:SF15 209 297 1.2E-131 T 23-04-2016 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 PANTHER PTHR10395:SF15 4 168 1.2E-131 T 23-04-2016 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 PIRSF PIRSF000241 1 300 3.5E-110 T 23-04-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 Gene3D G3DSA:3.10.270.10 3 298 3.9E-113 T 23-04-2016 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 186 293 1.0E-54 T 23-04-2016 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 SUPERFAMILY SSF55620 147 298 7.23E-57 T 23-04-2016 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 SUPERFAMILY SSF55620 4 139 3.38E-41 T 23-04-2016 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 Pfam PF01014 Uricase 151 288 1.4E-32 T 23-04-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 Pfam PF01014 Uricase 9 141 1.2E-19 T 23-04-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 TIGRFAM TIGR03383 urate_oxi: urate oxidase 5 293 3.5E-110 T 23-04-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 PANTHER PTHR10395 209 297 1.2E-131 T 23-04-2016 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 PANTHER PTHR10395 4 168 1.2E-131 T 23-04-2016 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 PRINTS PR00093 Uricase signature 172 184 3.4E-16 T 23-04-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 PRINTS PR00093 Uricase signature 156 172 3.4E-16 T 23-04-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 PRINTS PR00093 Uricase signature 86 99 3.4E-16 T 23-04-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 PRINTS PR00093 Uricase signature 50 64 3.4E-16 T 23-04-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 DC74_RS31350 419f6542a3ee909fe6846ce43c4a2a25 307 PRINTS PR00093 Uricase signature 11 22 3.4E-16 T 23-04-2016 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691|UniPathway: UPA00394 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 PRINTS PR00690 Adhesin family signature 205 226 6.4E-6 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 PRINTS PR00690 Adhesin family signature 69 82 6.4E-6 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 PRINTS PR00690 Adhesin family signature 258 276 6.4E-6 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 PRINTS PR00690 Adhesin family signature 38 56 6.4E-6 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 Gene3D G3DSA:3.40.50.1980 25 198 1.1E-41 T 23-04-2016 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 PRINTS PR00691 Adhesin B signature 149 168 2.6E-5 T 23-04-2016 IPR006129 Adhesin B GO:0007155 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 PRINTS PR00691 Adhesin B signature 38 59 2.6E-5 T 23-04-2016 IPR006129 Adhesin B GO:0007155 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 PRINTS PR00691 Adhesin B signature 63 81 2.6E-5 T 23-04-2016 IPR006129 Adhesin B GO:0007155 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 PRINTS PR00691 Adhesin B signature 296 314 2.6E-5 T 23-04-2016 IPR006129 Adhesin B GO:0007155 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 Gene3D G3DSA:3.40.50.1980 199 318 2.8E-30 T 23-04-2016 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 PANTHER PTHR30477:SF1 10 291 1.5E-57 T 23-04-2016 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 SUPERFAMILY SSF53807 20 318 3.92E-67 T 23-04-2016 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 Pfam PF01297 Zinc-uptake complex component A periplasmic 41 316 8.7E-65 T 23-04-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 DC74_RS14845 2219279424670ff4502b23c9334ce73b 320 PANTHER PTHR30477 10 291 1.5E-57 T 23-04-2016 DC74_RS25525 e84055b0cf0c151d95fdeda9e116f519 228 PANTHER PTHR24220 9 224 8.3E-108 T 23-04-2016 DC74_RS25525 e84055b0cf0c151d95fdeda9e116f519 228 SUPERFAMILY SSF52540 8 224 8.05E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25525 e84055b0cf0c151d95fdeda9e116f519 228 PANTHER PTHR24220:SF559 9 224 8.3E-108 T 23-04-2016 DC74_RS25525 e84055b0cf0c151d95fdeda9e116f519 228 Pfam PF00005 ABC transporter 23 171 3.5E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS25525 e84055b0cf0c151d95fdeda9e116f519 228 SMART SM00382 32 220 5.3E-19 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS25525 e84055b0cf0c151d95fdeda9e116f519 228 Gene3D G3DSA:3.40.50.300 7 222 8.1E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23825 5f878098db81f231909234e2ce56bc4e 359 Pfam PF08279 HTH domain 5 57 1.2E-16 T 23-04-2016 IPR013196 Helix-turn-helix, type 11 DC74_RS23825 5f878098db81f231909234e2ce56bc4e 359 Gene3D G3DSA:1.10.10.10 2 61 1.0E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23825 5f878098db81f231909234e2ce56bc4e 359 PANTHER PTHR34580 2 247 4.6E-31 T 23-04-2016 DC74_RS23825 5f878098db81f231909234e2ce56bc4e 359 PANTHER PTHR34580:SF3 2 247 4.6E-31 T 23-04-2016 DC74_RS23825 5f878098db81f231909234e2ce56bc4e 359 SUPERFAMILY SSF46785 3 57 5.46E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23825 5f878098db81f231909234e2ce56bc4e 359 Pfam PF13280 WYL domain 141 344 3.5E-28 T 23-04-2016 IPR026881 WYL domain DC74_RS38910 40f124134d36c06950820afa390430ef 529 PANTHER PTHR11938:SF8 1 23 7.9E-119 T 23-04-2016 DC74_RS38910 40f124134d36c06950820afa390430ef 529 PANTHER PTHR11938:SF8 161 327 7.9E-119 T 23-04-2016 DC74_RS38910 40f124134d36c06950820afa390430ef 529 PANTHER PTHR11938:SF8 125 134 7.9E-119 T 23-04-2016 DC74_RS38910 40f124134d36c06950820afa390430ef 529 Gene3D G3DSA:1.10.3650.10 350 428 9.4E-25 T 23-04-2016 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 DC74_RS38910 40f124134d36c06950820afa390430ef 529 Gene3D G3DSA:3.30.70.20 227 349 1.6E-67 T 23-04-2016 DC74_RS38910 40f124134d36c06950820afa390430ef 529 Gene3D G3DSA:3.30.70.20 430 454 1.6E-67 T 23-04-2016 DC74_RS38910 40f124134d36c06950820afa390430ef 529 PANTHER PTHR11938 1 23 7.9E-119 T 23-04-2016 DC74_RS38910 40f124134d36c06950820afa390430ef 529 PANTHER PTHR11938 161 327 7.9E-119 T 23-04-2016 DC74_RS38910 40f124134d36c06950820afa390430ef 529 PANTHER PTHR11938 125 134 7.9E-119 T 23-04-2016 DC74_RS38910 40f124134d36c06950820afa390430ef 529 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 349 430 1.7E-26 T 23-04-2016 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 DC74_RS38910 40f124134d36c06950820afa390430ef 529 Gene3D G3DSA:3.30.70.20 186 226 3.9E-25 T 23-04-2016 DC74_RS38910 40f124134d36c06950820afa390430ef 529 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 477 2.4E-221 T 23-04-2016 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 DC74_RS38910 40f124134d36c06950820afa390430ef 529 Pfam PF13247 4Fe-4S dicluster domain 166 262 2.5E-36 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS38910 40f124134d36c06950820afa390430ef 529 SUPERFAMILY SSF54862 1 479 2.2E-155 T 23-04-2016 DC74_RS38910 40f124134d36c06950820afa390430ef 529 Gene3D G3DSA:3.30.70.20 156 185 4.3E-11 T 23-04-2016 DC74_RS38910 40f124134d36c06950820afa390430ef 529 Gene3D G3DSA:3.30.70.20 2 18 4.3E-11 T 23-04-2016 DC74_RS30235 9de7358394f1406952f34224add80cb7 167 PANTHER PTHR10057 1 167 1.6E-23 T 23-04-2016 IPR004307 TspO/MBR-related protein GO:0016021 DC74_RS30235 9de7358394f1406952f34224add80cb7 167 PIRSF PIRSF005859 11 165 4.6E-36 T 23-04-2016 IPR004307 TspO/MBR-related protein GO:0016021 DC74_RS30235 9de7358394f1406952f34224add80cb7 167 Pfam PF03073 TspO/MBR family 22 161 1.5E-33 T 23-04-2016 IPR004307 TspO/MBR-related protein GO:0016021 DC74_RS36910 726d1c028c475e029d8818c0dbf4b51e 90 SUPERFAMILY SSF51004 21 75 5.49E-7 T 23-04-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain DC74_RS36910 726d1c028c475e029d8818c0dbf4b51e 90 Gene3D G3DSA:2.130.10.10 14 63 2.1E-6 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS30825 055df7b9788067f99a125367a54b7be6 301 SUPERFAMILY SSF161098 93 280 3.14E-26 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS30825 055df7b9788067f99a125367a54b7be6 301 Gene3D G3DSA:1.10.3720.10 92 277 6.0E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS30825 055df7b9788067f99a125367a54b7be6 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 279 2.3E-15 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS30825 055df7b9788067f99a125367a54b7be6 301 PANTHER PTHR30151 9 297 3.5E-106 T 23-04-2016 DC74_RS30825 055df7b9788067f99a125367a54b7be6 301 PANTHER PTHR30151:SF16 9 297 3.5E-106 T 23-04-2016 DC74_RS39435 dc4ab962a105ede293b3de305c6bd220 317 Gene3D G3DSA:3.40.190.10 174 266 8.2E-4 T 23-04-2016 DC74_RS39435 dc4ab962a105ede293b3de305c6bd220 317 Pfam PF03466 LysR substrate binding domain 88 291 8.4E-17 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS39435 dc4ab962a105ede293b3de305c6bd220 317 Gene3D G3DSA:3.40.190.10 102 173 8.6E-9 T 23-04-2016 DC74_RS39435 dc4ab962a105ede293b3de305c6bd220 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.2E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS39435 dc4ab962a105ede293b3de305c6bd220 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.2E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS39435 dc4ab962a105ede293b3de305c6bd220 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.2E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS39435 dc4ab962a105ede293b3de305c6bd220 317 Gene3D G3DSA:1.10.10.10 2 84 1.4E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39435 dc4ab962a105ede293b3de305c6bd220 317 SUPERFAMILY SSF46785 2 84 3.15E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39435 dc4ab962a105ede293b3de305c6bd220 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.8E-18 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS39435 dc4ab962a105ede293b3de305c6bd220 317 SUPERFAMILY SSF53850 100 299 5.79E-21 T 23-04-2016 DC74_RS39435 dc4ab962a105ede293b3de305c6bd220 317 PANTHER PTHR30346 1 313 6.2E-90 T 23-04-2016 DC74_RS39435 dc4ab962a105ede293b3de305c6bd220 317 PANTHER PTHR30346:SF7 1 313 6.2E-90 T 23-04-2016 DC74_RS14250 87e5aff7edfd335a87c670f165c8ff36 275 Gene3D G3DSA:3.40.50.620 26 222 3.7E-25 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS14250 87e5aff7edfd335a87c670f165c8ff36 275 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 28 226 7.6E-14 T 23-04-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 DC74_RS14250 87e5aff7edfd335a87c670f165c8ff36 275 SUPERFAMILY SSF52402 24 216 2.46E-22 T 23-04-2016 DC74_RS36880 26950a13f511d284713c8f3bbc49b96f 377 PANTHER PTHR30472 30 374 7.7E-161 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS36880 26950a13f511d284713c8f3bbc49b96f 377 Gene3D G3DSA:1.10.3470.10 38 372 4.6E-111 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS36880 26950a13f511d284713c8f3bbc49b96f 377 PANTHER PTHR30472:SF3 30 374 7.7E-161 T 23-04-2016 DC74_RS36880 26950a13f511d284713c8f3bbc49b96f 377 SUPERFAMILY SSF81345 35 368 1.19E-84 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS36880 26950a13f511d284713c8f3bbc49b96f 377 Pfam PF01032 FecCD transport family 52 368 3.7E-95 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS33805 72793137632a591beffeb90337f6718f 226 SMART SM00382 27 218 1.6E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS33805 72793137632a591beffeb90337f6718f 226 Pfam PF00005 ABC transporter 19 168 1.5E-24 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS33805 72793137632a591beffeb90337f6718f 226 Gene3D G3DSA:3.40.50.300 1 211 6.2E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33805 72793137632a591beffeb90337f6718f 226 PANTHER PTHR24220 3 211 2.6E-59 T 23-04-2016 DC74_RS33805 72793137632a591beffeb90337f6718f 226 SUPERFAMILY SSF52540 2 211 1.05E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12895 03e6f0f31b99040c94a2ca8835592a5f 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 143 216 2.3E-13 T 23-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 DC74_RS12895 03e6f0f31b99040c94a2ca8835592a5f 269 Gene3D G3DSA:1.10.760.10 156 223 4.7E-19 T 23-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 DC74_RS12895 03e6f0f31b99040c94a2ca8835592a5f 269 Gene3D G3DSA:1.10.760.10 48 124 9.1E-18 T 23-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 DC74_RS12895 03e6f0f31b99040c94a2ca8835592a5f 269 PIRSF PIRSF000007 1 263 9.7E-123 T 23-04-2016 IPR009152 Ubiquinol-cytochrome-c reductase, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 DC74_RS12895 03e6f0f31b99040c94a2ca8835592a5f 269 SUPERFAMILY SSF46626 13 129 1.28E-18 T 23-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 DC74_RS12895 03e6f0f31b99040c94a2ca8835592a5f 269 SUPERFAMILY SSF46626 124 216 3.55E-27 T 23-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 DC74_RS12895 03e6f0f31b99040c94a2ca8835592a5f 269 Gene3D G3DSA:1.10.760.10 125 155 3.3E-4 T 23-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 DC74_RS12895 03e6f0f31b99040c94a2ca8835592a5f 269 PANTHER PTHR33751:SF1 6 226 1.3E-64 T 23-04-2016 DC74_RS12895 03e6f0f31b99040c94a2ca8835592a5f 269 PANTHER PTHR33751 6 226 1.3E-64 T 23-04-2016 DC74_RS12895 03e6f0f31b99040c94a2ca8835592a5f 269 Pfam PF00034 Cytochrome c 50 125 4.1E-8 T 23-04-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 DC74_RS00005 32b1a42c90277bd39f8a2fdd3061761c 167 SUPERFAMILY SSF53098 8 140 7.74E-16 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS00005 32b1a42c90277bd39f8a2fdd3061761c 167 Gene3D G3DSA:3.30.420.10 9 145 9.1E-19 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS00005 32b1a42c90277bd39f8a2fdd3061761c 167 Pfam PF00665 Integrase core domain 10 134 1.8E-13 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 DC74_RS30700 c21f62dbcd7d779e0e0e288bdd9dee36 210 PANTHER PTHR38839 22 108 2.4E-17 T 23-04-2016 DC74_RS30700 c21f62dbcd7d779e0e0e288bdd9dee36 210 Pfam PF02467 Transcription factor WhiB 22 89 3.0E-21 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS30700 c21f62dbcd7d779e0e0e288bdd9dee36 210 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 9 173 21.579 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS16115 6f63b47c26b722758339579659afc567 275 PANTHER PTHR24220 27 275 3.1E-107 T 23-04-2016 DC74_RS16115 6f63b47c26b722758339579659afc567 275 PIRSF PIRSF039085 22 275 7.6E-96 T 23-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 DC74_RS16115 6f63b47c26b722758339579659afc567 275 Gene3D G3DSA:3.40.50.300 25 272 2.4E-81 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16115 6f63b47c26b722758339579659afc567 275 SUPERFAMILY SSF52540 25 270 2.32E-74 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16115 6f63b47c26b722758339579659afc567 275 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 26 275 1.4E-109 T 23-04-2016 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein DC74_RS16115 6f63b47c26b722758339579659afc567 275 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS16115 6f63b47c26b722758339579659afc567 275 SMART SM00382 50 248 1.7E-19 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS16115 6f63b47c26b722758339579659afc567 275 Pfam PF00005 ABC transporter 41 199 1.9E-34 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS16115 6f63b47c26b722758339579659afc567 275 PANTHER PTHR24220:SF327 27 275 3.1E-107 T 23-04-2016 DC74_RS12285 d76fe6569feffd7fb9834854a50d390f 344 PANTHER PTHR30589 1 281 6.1E-120 T 23-04-2016 DC74_RS12285 d76fe6569feffd7fb9834854a50d390f 344 PANTHER PTHR30589:SF0 1 281 6.1E-120 T 23-04-2016 DC74_RS12285 d76fe6569feffd7fb9834854a50d390f 344 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 140 152 - T 23-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 DC74_RS12285 d76fe6569feffd7fb9834854a50d390f 344 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 262 15.775 T 23-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 DC74_RS12285 d76fe6569feffd7fb9834854a50d390f 344 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 13 262 1.7E-43 T 23-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 DC74_RS12285 d76fe6569feffd7fb9834854a50d390f 344 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 257 1.2E-66 T 23-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 DC74_RS29480 aa6cc84ced0e9141f93b64c0b2a6cc53 544 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS29480 aa6cc84ced0e9141f93b64c0b2a6cc53 544 Pfam PF00501 AMP-binding enzyme 29 437 6.4E-56 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS29480 aa6cc84ced0e9141f93b64c0b2a6cc53 544 Gene3D G3DSA:2.30.38.10 357 430 6.7E-15 T 23-04-2016 DC74_RS29480 aa6cc84ced0e9141f93b64c0b2a6cc53 544 PANTHER PTHR22754 5 439 3.5E-64 T 23-04-2016 DC74_RS29480 aa6cc84ced0e9141f93b64c0b2a6cc53 544 Gene3D G3DSA:3.40.50.980 33 169 8.9E-20 T 23-04-2016 DC74_RS29480 aa6cc84ced0e9141f93b64c0b2a6cc53 544 SUPERFAMILY SSF56801 23 531 1.31E-81 T 23-04-2016 DC74_RS29480 aa6cc84ced0e9141f93b64c0b2a6cc53 544 Gene3D G3DSA:3.40.50.980 170 332 1.4E-23 T 23-04-2016 DC74_RS30855 3b98718a32de4545dbc8c7360335e94d 229 Gene3D G3DSA:3.40.50.620 7 202 2.5E-56 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS30855 3b98718a32de4545dbc8c7360335e94d 229 SUPERFAMILY SSF52402 15 191 3.84E-48 T 23-04-2016 DC74_RS30855 3b98718a32de4545dbc8c7360335e94d 229 PANTHER PTHR23293 8 229 6.1E-81 T 23-04-2016 DC74_RS30855 3b98718a32de4545dbc8c7360335e94d 229 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 43 205 1.6E-41 T 23-04-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 DC74_RS30855 3b98718a32de4545dbc8c7360335e94d 229 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 24 229 9.0E-58 T 23-04-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 DC74_RS30855 3b98718a32de4545dbc8c7360335e94d 229 PIRSF PIRSF000857 2 229 9.4E-91 T 23-04-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 DC74_RS30855 3b98718a32de4545dbc8c7360335e94d 229 PANTHER PTHR23293:SF5 8 229 6.1E-81 T 23-04-2016 DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 4.4E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 4.4E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 4.4E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 Gene3D G3DSA:3.40.50.2300 2 128 1.6E-37 T 23-04-2016 DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 SMART SM00448 3 120 2.9E-30 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 Pfam PF00072 Response regulator receiver domain 5 121 4.8E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 PANTHER PTHR26402:SF564 3 221 1.1E-98 T 23-04-2016 DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 215 3.9E-20 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 SUPERFAMILY SSF52172 4 192 8.19E-34 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 PANTHER PTHR26402 3 221 1.1E-98 T 23-04-2016 DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 SMART SM00421 158 215 2.7E-26 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13990 c99937770ef4acd3aee7c2ec64176a1a 226 Gene3D G3DSA:1.10.10.10 129 223 4.7E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08195 def3796b8de7e17669c15925f39620c5 389 Gene3D G3DSA:3.40.190.10 63 167 1.8E-9 T 23-04-2016 DC74_RS08195 def3796b8de7e17669c15925f39620c5 389 Gene3D G3DSA:3.40.190.10 168 319 5.2E-35 T 23-04-2016 DC74_RS08195 def3796b8de7e17669c15925f39620c5 389 PANTHER PTHR30222:SF5 39 338 2.8E-52 T 23-04-2016 DC74_RS08195 def3796b8de7e17669c15925f39620c5 389 Pfam PF13416 Bacterial extracellular solute-binding protein 64 331 1.4E-29 T 23-04-2016 DC74_RS08195 def3796b8de7e17669c15925f39620c5 389 SUPERFAMILY SSF53850 41 388 1.57E-59 T 23-04-2016 DC74_RS08195 def3796b8de7e17669c15925f39620c5 389 PANTHER PTHR30222 39 338 2.8E-52 T 23-04-2016 DC74_RS18395 8ca9744fcc67c3028c99da03f13df208 384 PANTHER PTHR10909 1 382 1.0E-119 T 23-04-2016 DC74_RS18395 8ca9744fcc67c3028c99da03f13df208 384 Gene3D G3DSA:2.40.110.10 126 222 1.4E-34 T 23-04-2016 DC74_RS18395 8ca9744fcc67c3028c99da03f13df208 384 SUPERFAMILY SSF47203 233 382 1.61E-17 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS18395 8ca9744fcc67c3028c99da03f13df208 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 220 3.7E-20 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS18395 8ca9744fcc67c3028c99da03f13df208 384 PANTHER PTHR10909:SF229 1 382 1.0E-119 T 23-04-2016 DC74_RS18395 8ca9744fcc67c3028c99da03f13df208 384 Gene3D G3DSA:1.10.540.10 1 124 1.4E-27 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS18395 8ca9744fcc67c3028c99da03f13df208 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 378 9.2E-27 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS18395 8ca9744fcc67c3028c99da03f13df208 384 SUPERFAMILY SSF56645 2 244 2.09E-72 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS18395 8ca9744fcc67c3028c99da03f13df208 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 123 3.0E-22 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS18395 8ca9744fcc67c3028c99da03f13df208 384 Gene3D G3DSA:1.20.140.10 223 382 2.8E-25 T 23-04-2016 DC74_RS32930 9135b08532a4292c9450c64194ea96b4 168 Gene3D G3DSA:1.10.10.10 12 160 1.6E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32930 9135b08532a4292c9450c64194ea96b4 168 SUPERFAMILY SSF46785 18 158 1.48E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32930 9135b08532a4292c9450c64194ea96b4 168 Pfam PF12802 MarR family 50 108 1.7E-14 T 23-04-2016 DC74_RS32930 9135b08532a4292c9450c64194ea96b4 168 PANTHER PTHR33164:SF4 3 160 1.0E-27 T 23-04-2016 DC74_RS32930 9135b08532a4292c9450c64194ea96b4 168 PANTHER PTHR33164 3 160 1.0E-27 T 23-04-2016 DC74_RS32930 9135b08532a4292c9450c64194ea96b4 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 5.1E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32930 9135b08532a4292c9450c64194ea96b4 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 5.1E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32930 9135b08532a4292c9450c64194ea96b4 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 135 155 5.1E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32930 9135b08532a4292c9450c64194ea96b4 168 ProSitePatterns PS01117 MarR-type HTH domain signature. 84 118 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS32930 9135b08532a4292c9450c64194ea96b4 168 SMART SM00347 44 145 1.9E-21 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS28020 33f42414e69d6731bbc24adb732fcce7 327 Pfam PF00188 Cysteine-rich secretory protein family 211 325 8.3E-19 T 23-04-2016 IPR014044 CAP domain DC74_RS28020 33f42414e69d6731bbc24adb732fcce7 327 PANTHER PTHR31157 205 326 1.6E-44 T 23-04-2016 DC74_RS28020 33f42414e69d6731bbc24adb732fcce7 327 Gene3D G3DSA:3.40.33.10 202 318 9.7E-13 T 23-04-2016 IPR014044 CAP domain DC74_RS28020 33f42414e69d6731bbc24adb732fcce7 327 SUPERFAMILY SSF55797 205 325 1.5E-24 T 23-04-2016 IPR014044 CAP domain DC74_RS16355 413b383adaeae57e6d280c71f9dcd04a 443 PANTHER PTHR30009 25 432 7.9E-174 T 23-04-2016 DC74_RS16355 413b383adaeae57e6d280c71f9dcd04a 443 Pfam PF02378 Phosphotransferase system, EIIC 33 362 8.3E-65 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 DC74_RS16355 413b383adaeae57e6d280c71f9dcd04a 443 PANTHER PTHR30009:SF2 25 432 7.9E-174 T 23-04-2016 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 Pfam PF03952 Enolase, N-terminal domain 16 146 3.4E-55 T 23-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 16 435 7.8E-204 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 Pfam PF00113 Enolase, C-terminal TIM barrel domain 152 432 5.2E-134 T 23-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 PRINTS PR00148 Enolase signature 373 390 1.3E-46 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 PRINTS PR00148 Enolase signature 344 358 1.3E-46 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 PRINTS PR00148 Enolase signature 119 135 1.3E-46 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 PRINTS PR00148 Enolase signature 49 63 1.3E-46 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 PRINTS PR00148 Enolase signature 321 332 1.3E-46 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 PRINTS PR00148 Enolase signature 173 186 1.3E-46 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 SMART SM01192 151 435 4.3E-227 T 23-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 Gene3D G3DSA:3.20.20.120 140 433 9.6E-140 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 ProSitePatterns PS00164 Enolase signature. 344 357 - T 23-04-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 Hamap MF_00318 Enolase [eno]. 14 421 45.072 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 PANTHER PTHR11902 14 431 4.7E-270 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 SUPERFAMILY SSF51604 150 434 1.44E-132 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 PIRSF PIRSF001400 13 434 2.0E-187 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 SUPERFAMILY SSF54826 16 150 3.38E-52 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 SMART SM01193 16 146 1.1E-87 T 23-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 DC74_RS17360 72e4132b0478e3777154f00a44997e4c 438 Gene3D G3DSA:3.30.390.10 16 137 2.8E-52 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS34800 dbd71ade47fc7adb76aebc59bee21649 390 Gene3D G3DSA:3.90.1200.10 165 345 5.5E-19 T 23-04-2016 DC74_RS34800 dbd71ade47fc7adb76aebc59bee21649 390 SUPERFAMILY SSF56112 38 362 8.16E-27 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS34800 dbd71ade47fc7adb76aebc59bee21649 390 Pfam PF01636 Phosphotransferase enzyme family 109 313 5.5E-19 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS15630 e1810834e39b1ecf6abd5870af43aaa7 138 Pfam PF04143 Sulphur transport 31 118 9.4E-10 T 23-04-2016 IPR007272 Sulphur transport domain DC74_RS05395 a6a106e7a00399470002e94e5836a422 532 PANTHER PTHR24095 17 514 1.8E-186 T 23-04-2016 DC74_RS05395 a6a106e7a00399470002e94e5836a422 532 Gene3D G3DSA:3.30.300.30 419 515 2.1E-30 T 23-04-2016 DC74_RS05395 a6a106e7a00399470002e94e5836a422 532 Pfam PF13193 AMP-binding enzyme C-terminal domain 431 505 1.6E-23 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS05395 a6a106e7a00399470002e94e5836a422 532 Gene3D G3DSA:2.30.38.10 348 416 6.3E-21 T 23-04-2016 DC74_RS05395 a6a106e7a00399470002e94e5836a422 532 Pfam PF00501 AMP-binding enzyme 17 422 3.2E-91 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS05395 a6a106e7a00399470002e94e5836a422 532 Gene3D G3DSA:3.40.50.980 175 318 2.5E-30 T 23-04-2016 DC74_RS05395 a6a106e7a00399470002e94e5836a422 532 Gene3D G3DSA:3.40.50.980 10 174 1.5E-36 T 23-04-2016 DC74_RS05395 a6a106e7a00399470002e94e5836a422 532 SUPERFAMILY SSF56801 10 514 3.27E-138 T 23-04-2016 DC74_RS05395 a6a106e7a00399470002e94e5836a422 532 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS16395 bb4fb3a9c02823857416de43ba222d03 197 Pfam PF09438 Domain of unknown function (DUF2017) 9 196 5.2E-59 T 23-04-2016 IPR018561 Domain of unknown function DUF2017 DC74_RS16280 d3efce7ed6fa304f00c83f2facda199e 763 Pfam PF00912 Transglycosylase 96 265 2.8E-57 T 23-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 DC74_RS16280 d3efce7ed6fa304f00c83f2facda199e 763 Gene3D G3DSA:3.40.710.10 266 687 5.8E-95 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS16280 d3efce7ed6fa304f00c83f2facda199e 763 SUPERFAMILY SSF56601 250 269 4.77E-81 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS16280 d3efce7ed6fa304f00c83f2facda199e 763 SUPERFAMILY SSF56601 298 668 4.77E-81 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS16280 d3efce7ed6fa304f00c83f2facda199e 763 PANTHER PTHR32282:SF8 19 746 1.1E-267 T 23-04-2016 DC74_RS16280 d3efce7ed6fa304f00c83f2facda199e 763 Gene3D G3DSA:1.10.3810.10 90 265 6.1E-65 T 23-04-2016 DC74_RS16280 d3efce7ed6fa304f00c83f2facda199e 763 SUPERFAMILY SSF53955 80 284 5.91E-64 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS16280 d3efce7ed6fa304f00c83f2facda199e 763 PANTHER PTHR32282 19 746 1.1E-267 T 23-04-2016 DC74_RS16280 d3efce7ed6fa304f00c83f2facda199e 763 Pfam PF00905 Penicillin binding protein transpeptidase domain 367 625 5.8E-30 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS31455 f17011068748730aff259b3d40d48025 127 PANTHER PTHR21366 1 127 4.5E-16 T 23-04-2016 DC74_RS31455 f17011068748730aff259b3d40d48025 127 Gene3D G3DSA:3.10.180.10 7 123 1.2E-19 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS31455 f17011068748730aff259b3d40d48025 127 PANTHER PTHR21366:SF4 1 127 4.5E-16 T 23-04-2016 DC74_RS31455 f17011068748730aff259b3d40d48025 127 SUPERFAMILY SSF54593 3 125 5.24E-22 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS31455 f17011068748730aff259b3d40d48025 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 119 4.3E-10 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS12190 adb182385de594529966704094ca4d83 224 SMART SM00448 3 123 2.0E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS12190 adb182385de594529966704094ca4d83 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 1.8E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12190 adb182385de594529966704094ca4d83 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 1.8E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12190 adb182385de594529966704094ca4d83 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 1.8E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12190 adb182385de594529966704094ca4d83 224 SUPERFAMILY SSF52172 1 136 2.99E-29 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS12190 adb182385de594529966704094ca4d83 224 SMART SM00421 158 215 5.9E-23 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12190 adb182385de594529966704094ca4d83 224 Gene3D G3DSA:3.40.50.2300 1 129 2.9E-34 T 23-04-2016 DC74_RS12190 adb182385de594529966704094ca4d83 224 Pfam PF00072 Response regulator receiver domain 5 122 2.8E-23 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS12190 adb182385de594529966704094ca4d83 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12190 adb182385de594529966704094ca4d83 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 4.4E-19 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12190 adb182385de594529966704094ca4d83 224 PANTHER PTHR26402 3 220 1.6E-77 T 23-04-2016 DC74_RS12190 adb182385de594529966704094ca4d83 224 SUPERFAMILY SSF46894 150 220 1.26E-20 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS12190 adb182385de594529966704094ca4d83 224 Gene3D G3DSA:1.10.10.10 130 221 1.2E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS12190 adb182385de594529966704094ca4d83 224 PANTHER PTHR26402:SF564 3 220 1.6E-77 T 23-04-2016 DC74_RS33165 6f1065722fe65f838be56aedbca54999 163 SUPERFAMILY SSF55874 45 152 6.16E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33165 6f1065722fe65f838be56aedbca54999 163 Gene3D G3DSA:3.30.565.10 53 153 2.0E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33165 6f1065722fe65f838be56aedbca54999 163 Pfam PF13581 Histidine kinase-like ATPase domain 28 130 1.2E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23310 a0bfa7561af2171531debebbc32dfcd8 160 Pfam PF02559 CarD-like/TRCF domain 3 110 1.4E-15 T 23-04-2016 IPR003711 CarD-like/TRCF domain DC74_RS23310 a0bfa7561af2171531debebbc32dfcd8 160 PANTHER PTHR38447 1 160 2.6E-70 T 23-04-2016 DC74_RS23310 a0bfa7561af2171531debebbc32dfcd8 160 SMART SM01058 2 112 1.2E-32 T 23-04-2016 IPR003711 CarD-like/TRCF domain DC74_RS23310 a0bfa7561af2171531debebbc32dfcd8 160 SUPERFAMILY SSF141259 2 65 3.66E-15 T 23-04-2016 IPR003711 CarD-like/TRCF domain DC74_RS11140 6b3c6ee22e540e8b424f466d1a227122 351 Pfam PF01032 FecCD transport family 37 345 3.0E-91 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS11140 6b3c6ee22e540e8b424f466d1a227122 351 PANTHER PTHR30472:SF31 1 351 4.4E-156 T 23-04-2016 DC74_RS11140 6b3c6ee22e540e8b424f466d1a227122 351 PANTHER PTHR30472 1 351 4.4E-156 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS11140 6b3c6ee22e540e8b424f466d1a227122 351 Gene3D G3DSA:1.10.3470.10 28 347 5.2E-100 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS11140 6b3c6ee22e540e8b424f466d1a227122 351 SUPERFAMILY SSF81345 30 346 1.29E-79 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS16540 bf3f5e36ab253d22e4a5069d09693016 501 PANTHER PTHR23501 282 455 4.7E-129 T 23-04-2016 DC74_RS16540 bf3f5e36ab253d22e4a5069d09693016 501 PANTHER PTHR23501:SF91 282 455 4.7E-129 T 23-04-2016 DC74_RS16540 bf3f5e36ab253d22e4a5069d09693016 501 Pfam PF07690 Major Facilitator Superfamily 51 345 1.2E-21 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS16540 bf3f5e36ab253d22e4a5069d09693016 501 SUPERFAMILY SSF103473 38 243 1.7E-36 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS16540 bf3f5e36ab253d22e4a5069d09693016 501 SUPERFAMILY SSF103473 275 462 1.7E-36 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS16540 bf3f5e36ab253d22e4a5069d09693016 501 Gene3D G3DSA:1.20.1250.20 76 230 1.2E-20 T 23-04-2016 DC74_RS16540 bf3f5e36ab253d22e4a5069d09693016 501 PANTHER PTHR23501 37 266 4.7E-129 T 23-04-2016 DC74_RS16540 bf3f5e36ab253d22e4a5069d09693016 501 Gene3D G3DSA:1.20.1250.20 298 461 1.5E-10 T 23-04-2016 DC74_RS16540 bf3f5e36ab253d22e4a5069d09693016 501 PANTHER PTHR23501:SF91 37 266 4.7E-129 T 23-04-2016 DC74_RS01645 c1745c6aef35537ad48402892ada4104 294 Gene3D G3DSA:1.10.260.40 3 79 2.9E-22 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS01645 c1745c6aef35537ad48402892ada4104 294 SUPERFAMILY SSF47413 28 79 1.07E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS01645 c1745c6aef35537ad48402892ada4104 294 PANTHER PTHR35010 1 286 2.0E-86 T 23-04-2016 DC74_RS01645 c1745c6aef35537ad48402892ada4104 294 Pfam PF13560 Helix-turn-helix domain 7 84 5.2E-17 T 23-04-2016 DC74_RS01645 c1745c6aef35537ad48402892ada4104 294 PANTHER PTHR35010:SF2 1 286 2.0E-86 T 23-04-2016 DC74_RS01645 c1745c6aef35537ad48402892ada4104 294 SMART SM00530 10 82 5.3E-7 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS34750 ef5ed9f2eb19bc25664ae6343f10219e 475 Pfam PF10282 Lactonase, 7-bladed beta-propeller 208 325 3.9E-9 T 23-04-2016 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31|UniPathway: UPA00115 DC74_RS34750 ef5ed9f2eb19bc25664ae6343f10219e 475 SUPERFAMILY SSF50974 42 343 2.2E-78 T 23-04-2016 IPR011045 Nitrous oxide reductase, N-terminal DC74_RS34750 ef5ed9f2eb19bc25664ae6343f10219e 475 PANTHER PTHR13833 54 343 1.8E-48 T 23-04-2016 DC74_RS34750 ef5ed9f2eb19bc25664ae6343f10219e 475 Gene3D G3DSA:2.130.10.10 51 345 1.3E-82 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS34750 ef5ed9f2eb19bc25664ae6343f10219e 475 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 94 135 1.4E-11 T 23-04-2016 IPR011964 YVTN beta-propeller repeat DC74_RS34750 ef5ed9f2eb19bc25664ae6343f10219e 475 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 136 177 2.3E-11 T 23-04-2016 IPR011964 YVTN beta-propeller repeat DC74_RS34750 ef5ed9f2eb19bc25664ae6343f10219e 475 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 304 343 2.8E-9 T 23-04-2016 IPR011964 YVTN beta-propeller repeat DC74_RS34750 ef5ed9f2eb19bc25664ae6343f10219e 475 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 178 219 2.0E-14 T 23-04-2016 IPR011964 YVTN beta-propeller repeat DC74_RS34750 ef5ed9f2eb19bc25664ae6343f10219e 475 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 220 261 3.7E-13 T 23-04-2016 IPR011964 YVTN beta-propeller repeat DC74_RS34750 ef5ed9f2eb19bc25664ae6343f10219e 475 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 58 92 2.4E-11 T 23-04-2016 IPR011964 YVTN beta-propeller repeat DC74_RS34750 ef5ed9f2eb19bc25664ae6343f10219e 475 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 262 303 1.9E-8 T 23-04-2016 IPR011964 YVTN beta-propeller repeat DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 PANTHER PTHR11533:SF190 629 709 1.2E-173 T 23-04-2016 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 PANTHER PTHR11533:SF190 23 602 1.2E-173 T 23-04-2016 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 SUPERFAMILY SSF55486 218 462 1.06E-74 T 23-04-2016 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 854 0.0 T 23-04-2016 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 SUPERFAMILY SSF63737 8 199 3.92E-38 T 23-04-2016 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 270 280 2.3E-18 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 323 335 2.3E-18 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 182 197 2.3E-18 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 304 319 2.3E-18 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 138 153 2.3E-18 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 PANTHER PTHR11533 23 602 1.2E-173 T 23-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 Pfam PF11838 ERAP1-like C-terminal domain 536 847 2.0E-61 T 23-04-2016 IPR024571 ERAP1-like C-terminal domain DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 Pfam PF01433 Peptidase family M1 87 396 3.7E-65 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 Gene3D G3DSA:1.10.390.10 317 464 4.1E-41 T 23-04-2016 DC74_RS15410 18105cb8bda8906ad29f9dfe2f85b1b2 862 PANTHER PTHR11533 629 709 1.2E-173 T 23-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 DC74_RS39260 246859b48abb9cc549ff7f8a5eb2be87 189 PANTHER PTHR21327 12 189 6.8E-67 T 23-04-2016 DC74_RS39260 246859b48abb9cc549ff7f8a5eb2be87 189 SUPERFAMILY SSF142695 11 161 6.67E-51 T 23-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 DC74_RS39260 246859b48abb9cc549ff7f8a5eb2be87 189 Pfam PF00925 GTP cyclohydrolase II 12 160 1.3E-54 T 23-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 DC74_RS39260 246859b48abb9cc549ff7f8a5eb2be87 189 PANTHER PTHR21327:SF6 12 189 6.8E-67 T 23-04-2016 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 269 337 2.0E-14 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 SUPERFAMILY SSF63380 2 105 2.51E-25 T 23-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 SUPERFAMILY SSF52343 92 238 6.42E-30 T 23-04-2016 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 SUPERFAMILY SSF54292 231 345 1.84E-26 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 Gene3D G3DSA:3.40.50.80 94 233 7.9E-35 T 23-04-2016 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 208 216 1.2E-7 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 53 60 1.2E-7 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 97 106 1.2E-7 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 112 131 1.2E-7 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 Gene3D G3DSA:3.10.20.30 234 344 9.8E-30 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 Pfam PF00175 Oxidoreductase NAD-binding domain 114 222 7.8E-12 T 23-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 295 303 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 Gene3D G3DSA:2.40.30.10 2 93 2.7E-25 T 23-04-2016 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 PANTHER PTHR19370 2 260 7.1E-56 T 23-04-2016 DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 Pfam PF00970 Oxidoreductase FAD-binding domain 5 102 6.3E-14 T 23-04-2016 IPR008333 Oxidoreductase, FAD-binding domain DC74_RS20485 9baeddd4c4fcd2573038d5010835ac1e 348 PANTHER PTHR19370:SF93 2 260 7.1E-56 T 23-04-2016 DC74_RS40670 9406f69f0c7912469033827f1341ac1f 205 Gene3D G3DSA:3.40.50.1820 1 194 6.0E-65 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS40670 9406f69f0c7912469033827f1341ac1f 205 SUPERFAMILY SSF53474 1 197 1.54E-50 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS40670 9406f69f0c7912469033827f1341ac1f 205 PANTHER PTHR23024:SF24 1 197 7.2E-61 T 23-04-2016 DC74_RS40670 9406f69f0c7912469033827f1341ac1f 205 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 39 51 - T 23-04-2016 IPR033140 Lipase, GDXG, putative serine active site DC74_RS40670 9406f69f0c7912469033827f1341ac1f 205 PANTHER PTHR23024 1 197 7.2E-61 T 23-04-2016 DC74_RS40670 9406f69f0c7912469033827f1341ac1f 205 Pfam PF07859 alpha/beta hydrolase fold 1 173 1.1E-57 T 23-04-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 DC74_RS08045 e48882d6ab4bd323648a5084d1f7f9e1 273 Gene3D G3DSA:3.10.310.10 129 259 4.2E-37 T 23-04-2016 DC74_RS08045 e48882d6ab4bd323648a5084d1f7f9e1 273 PANTHER PTHR13774:SF17 1 270 7.5E-94 T 23-04-2016 DC74_RS08045 e48882d6ab4bd323648a5084d1f7f9e1 273 PIRSF PIRSF016184 1 271 3.4E-46 T 23-04-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- DC74_RS08045 e48882d6ab4bd323648a5084d1f7f9e1 273 SUPERFAMILY SSF54506 2 269 4.8E-70 T 23-04-2016 DC74_RS08045 e48882d6ab4bd323648a5084d1f7f9e1 273 Pfam PF02567 Phenazine biosynthesis-like protein 6 267 7.3E-57 T 23-04-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- DC74_RS08045 e48882d6ab4bd323648a5084d1f7f9e1 273 Gene3D G3DSA:3.10.310.10 2 128 9.7E-42 T 23-04-2016 DC74_RS08045 e48882d6ab4bd323648a5084d1f7f9e1 273 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 267 5.0E-35 T 23-04-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- DC74_RS08045 e48882d6ab4bd323648a5084d1f7f9e1 273 PANTHER PTHR13774 1 270 7.5E-94 T 23-04-2016 DC74_RS18690 8f68605f7d9bdcaf3c795e41c8c3c829 93 PANTHER PTHR10744:SF1 10 92 9.3E-38 T 23-04-2016 DC74_RS18690 8f68605f7d9bdcaf3c795e41c8c3c829 93 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 13 91 25.129 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18690 8f68605f7d9bdcaf3c795e41c8c3c829 93 SUPERFAMILY SSF50249 15 92 4.28E-30 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS18690 8f68605f7d9bdcaf3c795e41c8c3c829 93 Gene3D G3DSA:2.40.50.140 15 92 2.6E-34 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS18690 8f68605f7d9bdcaf3c795e41c8c3c829 93 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 20 86 3.0E-32 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18690 8f68605f7d9bdcaf3c795e41c8c3c829 93 PANTHER PTHR10744 10 92 9.3E-38 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18690 8f68605f7d9bdcaf3c795e41c8c3c829 93 ProSitePatterns PS00056 Ribosomal protein S17 signature. 66 78 - T 23-04-2016 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18690 8f68605f7d9bdcaf3c795e41c8c3c829 93 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 15 86 1.2E-34 T 23-04-2016 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18690 8f68605f7d9bdcaf3c795e41c8c3c829 93 PRINTS PR00973 Ribosomal protein S17 family signature 34 57 1.3E-11 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18690 8f68605f7d9bdcaf3c795e41c8c3c829 93 PRINTS PR00973 Ribosomal protein S17 family signature 66 76 1.3E-11 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18690 8f68605f7d9bdcaf3c795e41c8c3c829 93 PRINTS PR00973 Ribosomal protein S17 family signature 76 83 1.3E-11 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18690 8f68605f7d9bdcaf3c795e41c8c3c829 93 Pfam PF00366 Ribosomal protein S17 20 87 4.2E-30 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 2.9E-28 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 PRINTS PR00149 Fumarate lyase superfamily signature 182 200 2.9E-28 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 2.9E-28 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 2.9E-28 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 23-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 6 462 5.7E-214 T 23-04-2016 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 PANTHER PTHR11444 1 461 1.3E-250 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 Gene3D G3DSA:1.10.275.10 5 141 8.4E-56 T 23-04-2016 IPR024083 Fumarase/histidase, N-terminal DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 Gene3D G3DSA:1.20.200.10 142 420 9.0E-94 T 23-04-2016 DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 Pfam PF10415 Fumarase C C-terminus 410 461 1.3E-20 T 23-04-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 SUPERFAMILY SSF48557 5 460 1.25E-154 T 23-04-2016 IPR008948 L-Aspartase-like GO:0003824 DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 Gene3D G3DSA:1.10.40.30 421 460 1.1E-20 T 23-04-2016 DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 PANTHER PTHR11444:SF25 1 461 1.3E-250 T 23-04-2016 DC74_RS06660 6d3c41cd6f3d7d6c2533d740622949e7 469 Pfam PF00206 Lyase 14 344 2.8E-109 T 23-04-2016 IPR022761 Fumarate lyase, N-terminal DC74_RS11235 fad6fc8b8e938360e334052548cf7a4e 311 PRINTS PR00721 Stomatin signature 111 128 1.6E-31 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS11235 fad6fc8b8e938360e334052548cf7a4e 311 PRINTS PR00721 Stomatin signature 155 173 1.6E-31 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS11235 fad6fc8b8e938360e334052548cf7a4e 311 PRINTS PR00721 Stomatin signature 76 97 1.6E-31 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS11235 fad6fc8b8e938360e334052548cf7a4e 311 PRINTS PR00721 Stomatin signature 174 195 1.6E-31 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS11235 fad6fc8b8e938360e334052548cf7a4e 311 PRINTS PR00721 Stomatin signature 28 50 1.6E-31 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS11235 fad6fc8b8e938360e334052548cf7a4e 311 PRINTS PR00721 Stomatin signature 131 154 1.6E-31 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS11235 fad6fc8b8e938360e334052548cf7a4e 311 PANTHER PTHR10264:SF27 4 290 1.0E-116 T 23-04-2016 DC74_RS11235 fad6fc8b8e938360e334052548cf7a4e 311 SMART SM00244 21 179 1.7E-52 T 23-04-2016 IPR001107 Band 7 domain DC74_RS11235 fad6fc8b8e938360e334052548cf7a4e 311 SUPERFAMILY SSF117892 52 186 1.96E-39 T 23-04-2016 IPR001107 Band 7 domain DC74_RS11235 fad6fc8b8e938360e334052548cf7a4e 311 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 23-04-2016 IPR018080 Band 7/stomatin-like, conserved site DC74_RS11235 fad6fc8b8e938360e334052548cf7a4e 311 PANTHER PTHR10264 4 290 1.0E-116 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS11235 fad6fc8b8e938360e334052548cf7a4e 311 Pfam PF01145 SPFH domain / Band 7 family 25 194 4.2E-35 T 23-04-2016 IPR001107 Band 7 domain DC74_RS08960 a6e574dbfcbb60c13845a7dbbc56257c 300 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 83 186 4.5E-17 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 DC74_RS08960 a6e574dbfcbb60c13845a7dbbc56257c 300 SUPERFAMILY SSF161098 85 277 8.37E-34 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS08960 a6e574dbfcbb60c13845a7dbbc56257c 300 PANTHER PTHR30614 5 296 1.2E-60 T 23-04-2016 DC74_RS08960 a6e574dbfcbb60c13845a7dbbc56257c 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 291 1.3E-18 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS08960 a6e574dbfcbb60c13845a7dbbc56257c 300 Gene3D G3DSA:1.10.3720.10 84 292 1.9E-39 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS36490 0fa16d58d977e45097a18147813f06ca 387 Pfam PF02515 CoA-transferase family III 4 368 9.5E-112 T 23-04-2016 IPR003673 CoA-transferase family III GO:0003824 DC74_RS36490 0fa16d58d977e45097a18147813f06ca 387 Gene3D G3DSA:3.40.50.10540 303 379 4.3E-94 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS36490 0fa16d58d977e45097a18147813f06ca 387 Gene3D G3DSA:3.40.50.10540 2 213 4.3E-94 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS36490 0fa16d58d977e45097a18147813f06ca 387 PANTHER PTHR24023:SF593 41 379 1.1E-23 T 23-04-2016 DC74_RS36490 0fa16d58d977e45097a18147813f06ca 387 PANTHER PTHR24023 41 379 1.1E-23 T 23-04-2016 DC74_RS36490 0fa16d58d977e45097a18147813f06ca 387 Gene3D G3DSA:3.30.1540.10 219 302 1.5E-26 T 23-04-2016 DC74_RS36490 0fa16d58d977e45097a18147813f06ca 387 SUPERFAMILY SSF89796 1 381 3.66E-121 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS35775 6a5d6beece38b6ad767449deb471afe8 279 SUPERFAMILY SSF51658 9 270 5.24E-57 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS35775 6a5d6beece38b6ad767449deb471afe8 279 Gene3D G3DSA:3.20.20.150 7 272 4.0E-68 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS35775 6a5d6beece38b6ad767449deb471afe8 279 PANTHER PTHR12110 1 271 4.1E-80 T 23-04-2016 DC74_RS35775 6a5d6beece38b6ad767449deb471afe8 279 PIRSF PIRSF006241 4 277 4.4E-79 T 23-04-2016 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 DC74_RS35775 6a5d6beece38b6ad767449deb471afe8 279 Pfam PF01261 Xylose isomerase-like TIM barrel 26 229 2.0E-26 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS35775 6a5d6beece38b6ad767449deb471afe8 279 PANTHER PTHR12110:SF3 1 271 4.1E-80 T 23-04-2016 DC74_RS05795 649e6adbf4610d8fc46009557ab8b8f9 463 PIRSF PIRSF500824 2 440 9.7E-184 T 23-04-2016 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS05795 649e6adbf4610d8fc46009557ab8b8f9 463 Gene3D G3DSA:3.40.50.1100 57 242 3.6E-47 T 23-04-2016 DC74_RS05795 649e6adbf4610d8fc46009557ab8b8f9 463 PANTHER PTHR10314 206 453 1.4E-196 T 23-04-2016 DC74_RS05795 649e6adbf4610d8fc46009557ab8b8f9 463 PANTHER PTHR10314 37 189 1.4E-196 T 23-04-2016 DC74_RS05795 649e6adbf4610d8fc46009557ab8b8f9 463 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 15 433 7.0E-167 T 23-04-2016 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS05795 649e6adbf4610d8fc46009557ab8b8f9 463 Gene3D G3DSA:3.40.50.1100 243 425 6.7E-12 T 23-04-2016 DC74_RS05795 649e6adbf4610d8fc46009557ab8b8f9 463 PIRSF PIRSF001413 11 437 4.2E-109 T 23-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS05795 649e6adbf4610d8fc46009557ab8b8f9 463 SUPERFAMILY SSF53686 52 430 2.49E-99 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS05795 649e6adbf4610d8fc46009557ab8b8f9 463 PANTHER PTHR10314:SF21 206 453 1.4E-196 T 23-04-2016 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS05795 649e6adbf4610d8fc46009557ab8b8f9 463 PANTHER PTHR10314:SF21 37 189 1.4E-196 T 23-04-2016 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS05795 649e6adbf4610d8fc46009557ab8b8f9 463 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 81 418 1.6E-47 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS28110 e4e10a291da67f4fed5972bf119a2d0f 146 Pfam PF00886 Ribosomal protein S16 9 67 1.1E-23 T 23-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28110 e4e10a291da67f4fed5972bf119a2d0f 146 Gene3D G3DSA:3.30.1320.10 2 83 1.4E-32 T 23-04-2016 IPR023803 Ribosomal protein S16 domain DC74_RS28110 e4e10a291da67f4fed5972bf119a2d0f 146 SUPERFAMILY SSF54565 2 98 1.31E-33 T 23-04-2016 IPR023803 Ribosomal protein S16 domain DC74_RS28110 e4e10a291da67f4fed5972bf119a2d0f 146 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.969 T 23-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28110 e4e10a291da67f4fed5972bf119a2d0f 146 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 23-04-2016 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28110 e4e10a291da67f4fed5972bf119a2d0f 146 PANTHER PTHR12919 2 135 3.2E-42 T 23-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28110 e4e10a291da67f4fed5972bf119a2d0f 146 PANTHER PTHR12919:SF20 2 135 3.2E-42 T 23-04-2016 DC74_RS28110 e4e10a291da67f4fed5972bf119a2d0f 146 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 4.7E-32 T 23-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS12230 6f6bb943eee52400088ff04d124eb7cd 243 SUPERFAMILY SSF56281 3 235 4.06E-43 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS12230 6f6bb943eee52400088ff04d124eb7cd 243 PANTHER PTHR11935 26 227 6.5E-25 T 23-04-2016 DC74_RS12230 6f6bb943eee52400088ff04d124eb7cd 243 Gene3D G3DSA:3.60.15.10 1 225 6.2E-40 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS12230 6f6bb943eee52400088ff04d124eb7cd 243 SMART SM00849 17 221 1.9E-24 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS12230 6f6bb943eee52400088ff04d124eb7cd 243 Pfam PF00753 Metallo-beta-lactamase superfamily 26 221 7.2E-21 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS36915 7c95b93322243e02f027a90a34b7c2e7 872 SUPERFAMILY SSF56112 230 416 1.91E-22 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS36915 7c95b93322243e02f027a90a34b7c2e7 872 SMART SM01260 539 866 4.6E-5 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS36915 7c95b93322243e02f027a90a34b7c2e7 872 SMART SM00220 230 529 1.1E-6 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS36915 7c95b93322243e02f027a90a34b7c2e7 872 SUPERFAMILY SSF158745 540 863 3.66E-23 T 23-04-2016 DC74_RS36915 7c95b93322243e02f027a90a34b7c2e7 872 PANTHER PTHR24362 229 427 1.4E-20 T 23-04-2016 DC74_RS36915 7c95b93322243e02f027a90a34b7c2e7 872 PANTHER PTHR24362:SF160 229 427 1.4E-20 T 23-04-2016 DC74_RS36915 7c95b93322243e02f027a90a34b7c2e7 872 Pfam PF00069 Protein kinase domain 241 432 2.3E-12 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS36915 7c95b93322243e02f027a90a34b7c2e7 872 Gene3D G3DSA:3.30.200.20 237 358 2.7E-8 T 23-04-2016 DC74_RS36915 7c95b93322243e02f027a90a34b7c2e7 872 Gene3D G3DSA:1.10.510.10 359 458 2.6E-9 T 23-04-2016 DC74_RS04870 74da96ed84cf97411b1839dd05a87985 295 PANTHER PTHR24322 192 227 1.7E-14 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04870 74da96ed84cf97411b1839dd05a87985 295 PANTHER PTHR24322:SF228 9 139 1.7E-14 T 23-04-2016 DC74_RS04870 74da96ed84cf97411b1839dd05a87985 295 Pfam PF00106 short chain dehydrogenase 6 147 4.9E-14 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04870 74da96ed84cf97411b1839dd05a87985 295 PANTHER PTHR24322:SF228 192 227 1.7E-14 T 23-04-2016 DC74_RS04870 74da96ed84cf97411b1839dd05a87985 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.1E-13 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04870 74da96ed84cf97411b1839dd05a87985 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 234 6.1E-13 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04870 74da96ed84cf97411b1839dd05a87985 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 6.1E-13 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04870 74da96ed84cf97411b1839dd05a87985 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 6.1E-13 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04870 74da96ed84cf97411b1839dd05a87985 295 PANTHER PTHR24322 9 139 1.7E-14 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04870 74da96ed84cf97411b1839dd05a87985 295 Gene3D G3DSA:3.40.50.720 5 259 3.5E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04870 74da96ed84cf97411b1839dd05a87985 295 SUPERFAMILY SSF51735 4 273 6.94E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS24620 f650c45cfccdffdf7ef30f71b193a3c1 380 PANTHER PTHR24220:SF374 34 44 1.2E-147 T 23-04-2016 DC74_RS24620 f650c45cfccdffdf7ef30f71b193a3c1 380 PANTHER PTHR24220:SF374 70 308 1.2E-147 T 23-04-2016 DC74_RS24620 f650c45cfccdffdf7ef30f71b193a3c1 380 Gene3D G3DSA:3.40.50.300 62 294 5.0E-81 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24620 f650c45cfccdffdf7ef30f71b193a3c1 380 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 66 322 6.8E-108 T 23-04-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 DC74_RS24620 f650c45cfccdffdf7ef30f71b193a3c1 380 SMART SM00382 82 279 1.2E-19 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS24620 f650c45cfccdffdf7ef30f71b193a3c1 380 PANTHER PTHR24220 34 44 1.2E-147 T 23-04-2016 DC74_RS24620 f650c45cfccdffdf7ef30f71b193a3c1 380 PANTHER PTHR24220 70 308 1.2E-147 T 23-04-2016 DC74_RS24620 f650c45cfccdffdf7ef30f71b193a3c1 380 SUPERFAMILY SSF52540 69 298 5.99E-78 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24620 f650c45cfccdffdf7ef30f71b193a3c1 380 Pfam PF00005 ABC transporter 74 221 4.8E-33 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS24620 f650c45cfccdffdf7ef30f71b193a3c1 380 ProSitePatterns PS00211 ABC transporters family signature. 194 208 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS33880 27277ad2d90c3cb7d523bc677ddacc9d 476 PANTHER PTHR10196 1 463 1.3E-110 T 23-04-2016 DC74_RS33880 27277ad2d90c3cb7d523bc677ddacc9d 476 SUPERFAMILY SSF53067 9 248 6.26E-54 T 23-04-2016 DC74_RS33880 27277ad2d90c3cb7d523bc677ddacc9d 476 TIGRFAM TIGR01312 XylB: xylulokinase 11 447 1.5E-134 T 23-04-2016 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 DC74_RS33880 27277ad2d90c3cb7d523bc677ddacc9d 476 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 9 246 1.2E-63 T 23-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 DC74_RS33880 27277ad2d90c3cb7d523bc677ddacc9d 476 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 341 361 - T 23-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 DC74_RS33880 27277ad2d90c3cb7d523bc677ddacc9d 476 Gene3D G3DSA:3.30.420.40 6 246 3.3E-54 T 23-04-2016 DC74_RS33880 27277ad2d90c3cb7d523bc677ddacc9d 476 PIRSF PIRSF000538 7 463 7.1E-81 T 23-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 DC74_RS33880 27277ad2d90c3cb7d523bc677ddacc9d 476 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 311 427 3.9E-15 T 23-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 DC74_RS33880 27277ad2d90c3cb7d523bc677ddacc9d 476 PANTHER PTHR10196:SF67 1 463 1.3E-110 T 23-04-2016 DC74_RS33880 27277ad2d90c3cb7d523bc677ddacc9d 476 Gene3D G3DSA:3.30.420.40 249 455 5.9E-20 T 23-04-2016 DC74_RS33880 27277ad2d90c3cb7d523bc677ddacc9d 476 SUPERFAMILY SSF53067 249 451 6.48E-32 T 23-04-2016 DC74_RS24740 8e68c5a4ecc893d17a7fb80509bf87f4 145 Gene3D G3DSA:1.20.1290.10 3 143 4.3E-47 T 23-04-2016 IPR029032 AhpD-like DC74_RS24740 8e68c5a4ecc893d17a7fb80509bf87f4 145 Pfam PF02627 Carboxymuconolactone decarboxylase family 8 90 5.3E-15 T 23-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS24740 8e68c5a4ecc893d17a7fb80509bf87f4 145 SUPERFAMILY SSF69118 3 142 6.89E-40 T 23-04-2016 IPR029032 AhpD-like DC74_RS24740 8e68c5a4ecc893d17a7fb80509bf87f4 145 PANTHER PTHR34846:SF2 27 138 5.7E-14 T 23-04-2016 DC74_RS24740 8e68c5a4ecc893d17a7fb80509bf87f4 145 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 26 73 5.0E-16 T 23-04-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS24740 8e68c5a4ecc893d17a7fb80509bf87f4 145 PANTHER PTHR34846 27 138 5.7E-14 T 23-04-2016 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PANTHER PTHR11712 2 392 3.3E-100 T 23-04-2016 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 SUPERFAMILY SSF48264 7 392 2.49E-100 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00385 P450 superfamily signature 341 352 6.5E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00385 P450 superfamily signature 332 341 6.5E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00385 P450 superfamily signature 230 247 6.5E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00385 P450 superfamily signature 265 276 6.5E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 Gene3D G3DSA:1.10.630.10 5 392 8.6E-134 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00359 B-class P450 signature 332 341 1.9E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00359 B-class P450 signature 265 276 1.9E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00359 B-class P450 signature 283 310 1.9E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00359 B-class P450 signature 130 146 1.9E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00359 B-class P450 signature 147 162 1.9E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00359 B-class P450 signature 341 352 1.9E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00359 B-class P450 signature 82 93 1.9E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00359 B-class P450 signature 311 326 1.9E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 PRINTS PR00359 B-class P450 signature 183 205 1.9E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS00870 4993bdac4d0bcdca764818407cc236a3 393 Pfam PF00067 Cytochrome P450 13 362 5.4E-26 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS05200 60220be7db6f4c0f6eddd0727e23a826 360 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 199 213 - T 23-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 DC74_RS05200 60220be7db6f4c0f6eddd0727e23a826 360 PANTHER PTHR30486 9 352 3.2E-135 T 23-04-2016 DC74_RS05200 60220be7db6f4c0f6eddd0727e23a826 360 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 9 348 1.1E-134 T 23-04-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 DC74_RS05200 60220be7db6f4c0f6eddd0727e23a826 360 SMART SM00382 128 253 6.3E-5 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS05200 60220be7db6f4c0f6eddd0727e23a826 360 Pfam PF00437 Type II/IV secretion system protein 129 261 5.5E-37 T 23-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 DC74_RS05200 60220be7db6f4c0f6eddd0727e23a826 360 SUPERFAMILY SSF52540 5 343 4.66E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05200 60220be7db6f4c0f6eddd0727e23a826 360 PANTHER PTHR30486:SF6 9 352 3.2E-135 T 23-04-2016 DC74_RS05200 60220be7db6f4c0f6eddd0727e23a826 360 Gene3D G3DSA:3.40.50.300 106 349 1.2E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 PANTHER PTHR11811:SF28 1 291 1.7E-163 T 23-04-2016 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 SUPERFAMILY SSF51735 1 143 2.46E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 Gene3D G3DSA:1.10.1040.10 162 270 8.6E-37 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 PANTHER PTHR11811 1 291 1.7E-163 T 23-04-2016 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 SUPERFAMILY SSF48179 158 290 2.58E-42 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 228 240 - T 23-04-2016 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 143 5.1E-37 T 23-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 224 251 3.2E-37 T 23-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 3.2E-37 T 23-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 3.2E-37 T 23-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 149 177 3.2E-37 T 23-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 3.2E-37 T 23-04-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 SMART SM01350 160 287 1.9E-6 T 23-04-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 Gene3D G3DSA:3.40.50.720 1 161 2.8E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 291 2.6E-103 T 23-04-2016 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 DC74_RS20680 e2415ef1154f04f56dba1c85069cf8df 292 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 160 270 3.3E-27 T 23-04-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|UniPathway: UPA00115 DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 SMART SM00471 434 566 3.1E-8 T 23-04-2016 IPR003607 HD/PDEase domain DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 827 94.026 T 23-04-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 SUPERFAMILY SSF55021 754 813 1.75E-7 T 23-04-2016 DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 SUPERFAMILY SSF109604 405 575 1.57E-16 T 23-04-2016 DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 39 608 5.5E-188 T 23-04-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 Gene3D G3DSA:3.30.460.10 67 128 3.1E-5 T 23-04-2016 DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 PANTHER PTHR13734:SF45 345 602 5.4E-81 T 23-04-2016 DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 SUPERFAMILY SSF81301 41 162 9.49E-17 T 23-04-2016 DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 PANTHER PTHR13734 345 602 5.4E-81 T 23-04-2016 DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 Gene3D G3DSA:3.30.70.260 756 809 1.7E-7 T 23-04-2016 DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 Gene3D G3DSA:1.10.3210.10 433 580 6.7E-19 T 23-04-2016 IPR006674 HD domain DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 Pfam PF08335 GlnD PII-uridylyltransferase 215 286 8.4E-6 T 23-04-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 Pfam PF01966 HD domain 439 555 6.6E-13 T 23-04-2016 IPR006674 HD domain DC74_RS28090 ca2ce45b2b063e596522104905868d06 827 SUPERFAMILY SSF81593 171 285 1.1E-5 T 23-04-2016 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 2.7E-11 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 2.7E-11 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 2.7E-11 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 164 259 1.1E-18 T 23-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 98 107 - T 23-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 Gene3D G3DSA:3.40.120.10 256 373 1.1E-31 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 Gene3D G3DSA:3.40.120.10 4 159 4.1E-43 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 138 6.0E-39 T 23-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 PANTHER PTHR22573 3 452 6.6E-148 T 23-04-2016 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 Gene3D G3DSA:3.30.310.50 375 450 5.1E-20 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 379 447 1.2E-13 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 373 2.1E-31 T 23-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 SUPERFAMILY SSF53738 263 369 8.63E-29 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 SUPERFAMILY SSF55957 364 452 2.35E-22 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 SUPERFAMILY SSF53738 163 261 2.0E-25 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 448 2.2E-171 T 23-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 Gene3D G3DSA:3.40.120.10 182 255 2.2E-23 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 PANTHER PTHR22573:SF15 3 452 6.6E-148 T 23-04-2016 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 450 44.267 T 23-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS18570 758222d9457438f354b1900e47d751dc 452 SUPERFAMILY SSF53738 4 185 1.53E-44 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS23920 ca5ba76aeaaa0da2049d8bc129105824 291 Pfam PF12697 Alpha/beta hydrolase family 39 278 2.6E-20 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS23920 ca5ba76aeaaa0da2049d8bc129105824 291 PANTHER PTHR10992:SF877 1 286 1.2E-80 T 23-04-2016 DC74_RS23920 ca5ba76aeaaa0da2049d8bc129105824 291 PANTHER PTHR10992 1 286 1.2E-80 T 23-04-2016 DC74_RS23920 ca5ba76aeaaa0da2049d8bc129105824 291 SUPERFAMILY SSF53474 7 284 2.23E-50 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS23920 ca5ba76aeaaa0da2049d8bc129105824 291 Gene3D G3DSA:3.40.50.1820 6 285 1.4E-55 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 Pfam PF02872 5'-nucleotidase, C-terminal domain 384 566 7.9E-26 T 23-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 Gene3D G3DSA:3.60.21.10 37 372 6.3E-58 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 PANTHER PTHR11575 172 418 1.9E-71 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 PANTHER PTHR11575 441 601 1.9E-71 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 PANTHER PTHR11575 40 152 1.9E-71 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 PRINTS PR01607 Apyrase family signature 286 309 3.2E-10 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 PRINTS PR01607 Apyrase family signature 42 60 3.2E-10 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 PRINTS PR01607 Apyrase family signature 462 485 3.2E-10 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 PRINTS PR01607 Apyrase family signature 540 559 3.2E-10 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 PRINTS PR01607 Apyrase family signature 317 337 3.2E-10 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 PRINTS PR01607 Apyrase family signature 253 270 3.2E-10 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 Pfam PF00149 Calcineurin-like phosphoesterase 48 303 1.6E-5 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 PANTHER PTHR11575:SF7 172 418 1.9E-71 T 23-04-2016 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 PANTHER PTHR11575:SF7 441 601 1.9E-71 T 23-04-2016 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 PANTHER PTHR11575:SF7 40 152 1.9E-71 T 23-04-2016 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 SUPERFAMILY SSF56300 42 374 3.04E-50 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 SUPERFAMILY SSF55816 383 603 2.35E-33 T 23-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 DC74_RS09860 c5a38374c09041bd6db98fa4d2014f04 656 Gene3D G3DSA:3.90.780.10 384 603 7.1E-37 T 23-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 DC74_RS23240 3b1e06b8e7c4c5d243f1247478131349 207 Gene3D G3DSA:3.40.630.30 13 202 7.7E-54 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS23240 3b1e06b8e7c4c5d243f1247478131349 207 SUPERFAMILY SSF55729 19 193 1.18E-46 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS23240 3b1e06b8e7c4c5d243f1247478131349 207 PANTHER PTHR13256 19 198 1.1E-51 T 23-04-2016 DC74_RS23240 3b1e06b8e7c4c5d243f1247478131349 207 Pfam PF13302 Acetyltransferase (GNAT) domain 27 169 3.3E-29 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS23240 3b1e06b8e7c4c5d243f1247478131349 207 PANTHER PTHR13256:SF43 19 198 1.1E-51 T 23-04-2016 DC74_RS17420 d48bad7a8e33f5b006f45f07c2639adc 558 PANTHER PTHR24362:SF160 521 533 1.6E-96 T 23-04-2016 DC74_RS17420 d48bad7a8e33f5b006f45f07c2639adc 558 PANTHER PTHR24362:SF160 3 375 1.6E-96 T 23-04-2016 DC74_RS17420 d48bad7a8e33f5b006f45f07c2639adc 558 SUPERFAMILY SSF56112 4 315 2.7E-75 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS17420 d48bad7a8e33f5b006f45f07c2639adc 558 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS17420 d48bad7a8e33f5b006f45f07c2639adc 558 PANTHER PTHR24362 3 375 1.6E-96 T 23-04-2016 DC74_RS17420 d48bad7a8e33f5b006f45f07c2639adc 558 PANTHER PTHR24362 521 533 1.6E-96 T 23-04-2016 DC74_RS17420 d48bad7a8e33f5b006f45f07c2639adc 558 Gene3D G3DSA:1.25.40.10 384 534 2.2E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS17420 d48bad7a8e33f5b006f45f07c2639adc 558 SMART SM00220 10 276 7.7E-55 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS17420 d48bad7a8e33f5b006f45f07c2639adc 558 Gene3D G3DSA:1.10.510.10 80 269 2.2E-47 T 23-04-2016 DC74_RS17420 d48bad7a8e33f5b006f45f07c2639adc 558 SUPERFAMILY SSF48452 418 531 2.8E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS17420 d48bad7a8e33f5b006f45f07c2639adc 558 Pfam PF00069 Protein kinase domain 10 266 3.4E-42 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS17420 d48bad7a8e33f5b006f45f07c2639adc 558 Gene3D G3DSA:3.30.200.20 3 79 4.1E-22 T 23-04-2016 DC74_RS29225 fe419627e643303688ddb10e0e3ae8e2 254 PIRSF PIRSF010219 1 223 1.9E-84 T 23-04-2016 IPR016566 Uncharacterised conserved protein UCP010219 DC74_RS29225 fe419627e643303688ddb10e0e3ae8e2 254 Pfam PF11361 Protein of unknown function (DUF3159) 23 207 1.6E-56 T 23-04-2016 IPR016566 Uncharacterised conserved protein UCP010219 DC74_RS38830 b5a97603ad3c72509eb7373dfbc4ec98 342 PANTHER PTHR13812:SF19 2 333 3.5E-28 T 23-04-2016 DC74_RS38830 b5a97603ad3c72509eb7373dfbc4ec98 342 PIRSF PIRSF001439 3 333 4.6E-77 T 23-04-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin DC74_RS38830 b5a97603ad3c72509eb7373dfbc4ec98 342 Gene3D G3DSA:3.30.1780.10 8 148 1.8E-37 T 23-04-2016 IPR023401 Ornithine cyclodeaminase, N-terminal DC74_RS38830 b5a97603ad3c72509eb7373dfbc4ec98 342 Gene3D G3DSA:3.40.50.720 149 304 3.5E-15 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38830 b5a97603ad3c72509eb7373dfbc4ec98 342 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 26 323 7.3E-31 T 23-04-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin DC74_RS38830 b5a97603ad3c72509eb7373dfbc4ec98 342 PANTHER PTHR13812 2 333 3.5E-28 T 23-04-2016 DC74_RS38830 b5a97603ad3c72509eb7373dfbc4ec98 342 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 9 334 1.2E-124 T 23-04-2016 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB DC74_RS38830 b5a97603ad3c72509eb7373dfbc4ec98 342 SUPERFAMILY SSF51735 8 331 4.65E-62 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00020 c7f4c76ea47c718e2c46d5a3fd432303 287 Pfam PF00480 ROK family 5 261 5.0E-19 T 23-04-2016 IPR000600 ROK family DC74_RS00020 c7f4c76ea47c718e2c46d5a3fd432303 287 Gene3D G3DSA:3.30.420.40 130 256 5.5E-24 T 23-04-2016 DC74_RS00020 c7f4c76ea47c718e2c46d5a3fd432303 287 SUPERFAMILY SSF53067 5 278 5.03E-31 T 23-04-2016 DC74_RS00020 c7f4c76ea47c718e2c46d5a3fd432303 287 PANTHER PTHR18964:SF108 4 283 2.9E-13 T 23-04-2016 DC74_RS00020 c7f4c76ea47c718e2c46d5a3fd432303 287 PANTHER PTHR18964 4 283 2.9E-13 T 23-04-2016 DC74_RS00020 c7f4c76ea47c718e2c46d5a3fd432303 287 Gene3D G3DSA:3.30.420.40 5 129 3.1E-10 T 23-04-2016 DC74_RS36220 14a50b084f3f5f604643852022a4df40 260 Gene3D G3DSA:2.60.120.620 162 243 1.5E-6 T 23-04-2016 DC74_RS36220 14a50b084f3f5f604643852022a4df40 260 Gene3D G3DSA:1.10.287.110 49 89 4.8E-4 T 23-04-2016 IPR001623 DnaJ domain DC74_RS36220 14a50b084f3f5f604643852022a4df40 260 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 136 247 3.5E-9 T 23-04-2016 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 DC74_RS36220 14a50b084f3f5f604643852022a4df40 260 SUPERFAMILY SSF46565 48 87 3.53E-5 T 23-04-2016 IPR001623 DnaJ domain DC74_RS38805 cac7e4cbe3739f68e1c5611bf991e77d 217 PANTHER PTHR38847:SF2 29 215 2.7E-98 T 23-04-2016 DC74_RS38805 cac7e4cbe3739f68e1c5611bf991e77d 217 Pfam PF14273 Domain of unknown function (DUF4360) 35 213 9.9E-67 T 23-04-2016 IPR025649 Protein of unknown function DUF4360 DC74_RS38805 cac7e4cbe3739f68e1c5611bf991e77d 217 PANTHER PTHR38847 29 215 2.7E-98 T 23-04-2016 DC74_RS24370 75352ee70ea48d90deb920648fc9db45 596 Gene3D G3DSA:2.70.70.10 446 589 1.3E-38 T 23-04-2016 DC74_RS24370 75352ee70ea48d90deb920648fc9db45 596 SUPERFAMILY SSF51261 468 588 6.28E-38 T 23-04-2016 IPR011055 Duplicated hybrid motif DC74_RS24370 75352ee70ea48d90deb920648fc9db45 596 PANTHER PTHR21666 427 594 2.0E-36 T 23-04-2016 DC74_RS24370 75352ee70ea48d90deb920648fc9db45 596 Pfam PF01551 Peptidase family M23 491 584 2.0E-25 T 23-04-2016 IPR016047 Peptidase M23 DC74_RS10255 831e91b8f2614851d09b62d503437f7a 318 PANTHER PTHR30371:SF0 6 278 3.7E-75 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS10255 831e91b8f2614851d09b62d503437f7a 318 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 17 44 6.9E-35 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS10255 831e91b8f2614851d09b62d503437f7a 318 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 125 151 6.9E-35 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS10255 831e91b8f2614851d09b62d503437f7a 318 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 107 125 6.9E-35 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS10255 831e91b8f2614851d09b62d503437f7a 318 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 175 203 6.9E-35 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS10255 831e91b8f2614851d09b62d503437f7a 318 PANTHER PTHR30371 6 278 3.7E-75 T 23-04-2016 DC74_RS10255 831e91b8f2614851d09b62d503437f7a 318 Pfam PF00902 Sec-independent protein translocase protein (TatC) 21 243 3.5E-57 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS10255 831e91b8f2614851d09b62d503437f7a 318 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 18 248 2.1E-52 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS10255 831e91b8f2614851d09b62d503437f7a 318 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 7 262 16.3 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 Gene3D G3DSA:2.60.120.10 294 398 2.9E-16 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 Gene3D G3DSA:1.10.441.10 140 238 1.3E-22 T 23-04-2016 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 Gene3D G3DSA:1.10.441.10 281 293 1.3E-22 T 23-04-2016 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 PRINTS PR00714 Phosphomannose isomerase type I signature 31 46 8.9E-65 T 23-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 PRINTS PR00714 Phosphomannose isomerase type I signature 227 242 8.9E-65 T 23-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 PRINTS PR00714 Phosphomannose isomerase type I signature 281 300 8.9E-65 T 23-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 PRINTS PR00714 Phosphomannose isomerase type I signature 262 281 8.9E-65 T 23-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 8.9E-65 T 23-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 PRINTS PR00714 Phosphomannose isomerase type I signature 243 262 8.9E-65 T 23-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 PRINTS PR00714 Phosphomannose isomerase type I signature 80 101 8.9E-65 T 23-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 PRINTS PR00714 Phosphomannose isomerase type I signature 125 148 8.9E-65 T 23-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 PANTHER PTHR10309:SF0 1 398 7.3E-118 T 23-04-2016 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 Gene3D G3DSA:2.60.120.10 245 280 1.7E-60 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 Gene3D G3DSA:2.60.120.10 6 139 1.7E-60 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 PANTHER PTHR10309 1 398 7.3E-118 T 23-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 Pfam PF01238 Phosphomannose isomerase type I 3 360 2.9E-68 T 23-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 125 133 - T 23-04-2016 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 SUPERFAMILY SSF51182 2 394 1.09E-96 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 PIRSF PIRSF001480 1 400 5.7E-96 T 23-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 DC74_RS16950 2c0e0e6092f47167932d6f8a54fe6acf 400 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 4 394 4.2E-71 T 23-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 DC74_RS27460 05d0cb4dc05737187d46bc698c985d1a 419 SUPERFAMILY SSF53383 4 417 7.09E-174 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS27460 05d0cb4dc05737187d46bc698c985d1a 419 Gene3D G3DSA:3.90.1150.10 284 417 3.1E-48 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS27460 05d0cb4dc05737187d46bc698c985d1a 419 PANTHER PTHR11680 3 416 2.8E-247 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS27460 05d0cb4dc05737187d46bc698c985d1a 419 Gene3D G3DSA:3.40.640.10 37 283 7.0E-107 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS27460 05d0cb4dc05737187d46bc698c985d1a 419 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 23-04-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS27460 05d0cb4dc05737187d46bc698c985d1a 419 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 50.935 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS27460 05d0cb4dc05737187d46bc698c985d1a 419 PIRSF PIRSF000412 1 414 1.5E-157 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS27460 05d0cb4dc05737187d46bc698c985d1a 419 Pfam PF00464 Serine hydroxymethyltransferase 9 389 1.6E-165 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS20160 a21ad0bf85465a5d05f7157d5b7e72a8 521 Gene3D G3DSA:3.40.1010.10 23 155 2.2E-36 T 23-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 DC74_RS20160 a21ad0bf85465a5d05f7157d5b7e72a8 521 PANTHER PTHR21091 24 435 7.5E-39 T 23-04-2016 DC74_RS20160 a21ad0bf85465a5d05f7157d5b7e72a8 521 SUPERFAMILY SSF53790 273 505 7.33E-53 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS20160 a21ad0bf85465a5d05f7157d5b7e72a8 521 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 25 236 1.4E-52 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS20160 a21ad0bf85465a5d05f7157d5b7e72a8 521 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 276 482 7.3E-36 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS20160 a21ad0bf85465a5d05f7157d5b7e72a8 521 SUPERFAMILY SSF53790 20 260 2.75E-49 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS20160 a21ad0bf85465a5d05f7157d5b7e72a8 521 Gene3D G3DSA:3.40.1010.10 274 387 3.1E-28 T 23-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 DC74_RS20160 a21ad0bf85465a5d05f7157d5b7e72a8 521 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 29 43 - T 23-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 DC74_RS20160 a21ad0bf85465a5d05f7157d5b7e72a8 521 Gene3D G3DSA:3.30.950.10 388 499 8.5E-12 T 23-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 DC74_RS20160 a21ad0bf85465a5d05f7157d5b7e72a8 521 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 276 518 2.3E-82 T 23-04-2016 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 DC74_RS20160 a21ad0bf85465a5d05f7157d5b7e72a8 521 PANTHER PTHR21091:SF127 24 435 7.5E-39 T 23-04-2016 DC74_RS20160 a21ad0bf85465a5d05f7157d5b7e72a8 521 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 24 256 4.7E-65 T 23-04-2016 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 DC74_RS32260 c6c3764c733ca54107f8790c979e8e23 287 Pfam PF13460 NAD(P)H-binding 7 174 1.0E-20 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32260 c6c3764c733ca54107f8790c979e8e23 287 SUPERFAMILY SSF51735 2 235 2.56E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32260 c6c3764c733ca54107f8790c979e8e23 287 PANTHER PTHR14194 1 287 8.9E-50 T 23-04-2016 DC74_RS32260 c6c3764c733ca54107f8790c979e8e23 287 Gene3D G3DSA:3.40.50.720 1 207 8.5E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32260 c6c3764c733ca54107f8790c979e8e23 287 PANTHER PTHR14194:SF21 1 287 8.9E-50 T 23-04-2016 DC74_RS17615 0ff05ca2cfc2d2463adf5e8215c6880b 313 Gene3D G3DSA:3.30.230.10 9 165 7.1E-48 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS17615 0ff05ca2cfc2d2463adf5e8215c6880b 313 Pfam PF08544 GHMP kinases C terminal 216 292 2.8E-8 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain DC74_RS17615 0ff05ca2cfc2d2463adf5e8215c6880b 313 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 8 286 6.1E-47 T 23-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS17615 0ff05ca2cfc2d2463adf5e8215c6880b 313 PANTHER PTHR20861:SF2 3 300 3.4E-76 T 23-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS17615 0ff05ca2cfc2d2463adf5e8215c6880b 313 PANTHER PTHR20861 3 300 3.4E-76 T 23-04-2016 DC74_RS17615 0ff05ca2cfc2d2463adf5e8215c6880b 313 PIRSF PIRSF010376 7 309 3.9E-75 T 23-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS17615 0ff05ca2cfc2d2463adf5e8215c6880b 313 SUPERFAMILY SSF55060 171 295 5.47E-22 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain DC74_RS17615 0ff05ca2cfc2d2463adf5e8215c6880b 313 SUPERFAMILY SSF54211 9 165 6.68E-40 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS17615 0ff05ca2cfc2d2463adf5e8215c6880b 313 Gene3D G3DSA:3.30.70.890 171 298 2.4E-26 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain DC74_RS17615 0ff05ca2cfc2d2463adf5e8215c6880b 313 Pfam PF00288 GHMP kinases N terminal domain 93 151 5.3E-7 T 23-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 DC74_RS17615 0ff05ca2cfc2d2463adf5e8215c6880b 313 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 9 302 29.904 T 23-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 321 4.2E-67 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PIRSF PIRSF000350 1 446 3.7E-72 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 1.1E-33 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 1.1E-33 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 1.1E-33 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 1.1E-33 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.1E-33 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 43 53 - T 23-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 Gene3D G3DSA:3.50.50.60 138 327 6.3E-48 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 Gene3D G3DSA:3.50.50.60 9 137 1.2E-38 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 SUPERFAMILY SSF51905 7 366 1.12E-59 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PANTHER PTHR22912:SF125 1 453 5.3E-184 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PANTHER PTHR22912 1 453 5.3E-184 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 449 6.4E-24 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 9 459 4.8E-137 T 23-04-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.5E-63 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 3.5E-63 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 3.5E-63 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 3.5E-63 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 3.5E-63 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 3.5E-63 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 3.5E-63 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 3.5E-63 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 3.5E-63 T 23-04-2016 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 SUPERFAMILY SSF55424 338 459 7.04E-29 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS13050 fe2a61d366df9786ac5418d704116828 462 Gene3D G3DSA:3.30.390.30 328 458 3.5E-28 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 464 35.136 T 23-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 SUPERFAMILY SSF52374 4 311 1.05E-85 T 23-04-2016 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 SUPERFAMILY SSF47323 320 463 1.7E-30 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 Pfam PF09190 DALR domain 340 393 4.9E-10 T 23-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 Gene3D G3DSA:3.40.50.620 21 303 1.1E-94 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 PANTHER PTHR10890 3 463 1.2E-195 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 Gene3D G3DSA:1.20.120.640 304 392 6.4E-19 T 23-04-2016 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 SMART SM00840 340 401 8.3E-15 T 23-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.9E-27 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.9E-27 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 190 208 2.9E-27 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 221 242 2.9E-27 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 462 1.3E-136 T 23-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 DC74_RS23330 505ef7f164562dd5c47372e853502cd7 464 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 311 1.8E-118 T 23-04-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 DC74_RS05270 849d13aa4568b1f1cbc61db995b783a2 413 Gene3D G3DSA:3.30.470.20 104 337 1.7E-30 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS05270 849d13aa4568b1f1cbc61db995b783a2 413 SUPERFAMILY SSF56059 91 328 8.13E-40 T 23-04-2016 DC74_RS05270 849d13aa4568b1f1cbc61db995b783a2 413 SMART SM01209 111 292 1.6E-4 T 23-04-2016 DC74_RS05270 849d13aa4568b1f1cbc61db995b783a2 413 Pfam PF13535 ATP-grasp domain 146 297 1.1E-19 T 23-04-2016 DC74_RS05270 849d13aa4568b1f1cbc61db995b783a2 413 PANTHER PTHR23132 84 300 5.9E-16 T 23-04-2016 DC74_RS11615 0820f5a76d25d6acfc5cbfaa87fd2248 178 Pfam PF00583 Acetyltransferase (GNAT) family 69 148 7.9E-13 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS11615 0820f5a76d25d6acfc5cbfaa87fd2248 178 Gene3D G3DSA:3.40.630.30 4 157 1.0E-30 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS11615 0820f5a76d25d6acfc5cbfaa87fd2248 178 PANTHER PTHR23091 7 166 2.9E-14 T 23-04-2016 DC74_RS11615 0820f5a76d25d6acfc5cbfaa87fd2248 178 SUPERFAMILY SSF55729 7 154 2.4E-29 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS07555 7c16693cefe6e3ebc489f4a0104018e1 307 Gene3D G3DSA:3.30.360.10 128 305 4.0E-56 T 23-04-2016 DC74_RS07555 7c16693cefe6e3ebc489f4a0104018e1 307 PANTHER PTHR22604:SF126 1 306 3.0E-97 T 23-04-2016 DC74_RS07555 7c16693cefe6e3ebc489f4a0104018e1 307 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 121 1.8E-13 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 DC74_RS07555 7c16693cefe6e3ebc489f4a0104018e1 307 SUPERFAMILY SSF51735 1 146 1.01E-32 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07555 7c16693cefe6e3ebc489f4a0104018e1 307 SUPERFAMILY SSF55347 123 265 1.14E-32 T 23-04-2016 DC74_RS07555 7c16693cefe6e3ebc489f4a0104018e1 307 Gene3D G3DSA:3.40.50.720 1 127 1.6E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07555 7c16693cefe6e3ebc489f4a0104018e1 307 PANTHER PTHR22604 1 306 3.0E-97 T 23-04-2016 DC74_RS04910 ecb1da7c8476d6a8c931fe8af6a466b9 283 PANTHER PTHR14194 1 231 1.1E-63 T 23-04-2016 DC74_RS04910 ecb1da7c8476d6a8c931fe8af6a466b9 283 PANTHER PTHR14194:SF46 1 231 1.1E-63 T 23-04-2016 DC74_RS04910 ecb1da7c8476d6a8c931fe8af6a466b9 283 Pfam PF05368 NmrA-like family 6 227 8.0E-44 T 23-04-2016 IPR008030 NmrA-like domain DC74_RS04910 ecb1da7c8476d6a8c931fe8af6a466b9 283 Gene3D G3DSA:3.40.50.720 4 223 5.8E-56 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04910 ecb1da7c8476d6a8c931fe8af6a466b9 283 SUPERFAMILY SSF51735 5 253 2.1E-62 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03710 77c07f2702bb97189e43d0e613b0711b 375 Gene3D G3DSA:3.40.50.280 106 231 3.0E-24 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS03710 77c07f2702bb97189e43d0e613b0711b 375 Pfam PF02310 B12 binding domain 108 220 3.4E-18 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS03710 77c07f2702bb97189e43d0e613b0711b 375 SUPERFAMILY SSF52242 104 229 2.83E-22 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS03710 77c07f2702bb97189e43d0e613b0711b 375 Pfam PF02607 B12 binding domain 23 93 4.6E-10 T 23-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain DC74_RS38585 4d99304f616bcd369eab37dceb669461 460 Pfam PF06969 HemN C-terminal domain 373 434 1.1E-8 T 23-04-2016 IPR010723 HemN, C-terminal DC74_RS38585 4d99304f616bcd369eab37dceb669461 460 PANTHER PTHR13932 55 456 1.6E-72 T 23-04-2016 DC74_RS38585 4d99304f616bcd369eab37dceb669461 460 Pfam PF04055 Radical SAM superfamily 59 232 2.1E-13 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS38585 4d99304f616bcd369eab37dceb669461 460 SUPERFAMILY SSF102114 40 446 4.05E-73 T 23-04-2016 DC74_RS38585 4d99304f616bcd369eab37dceb669461 460 SMART SM00729 54 277 8.4E-31 T 23-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 DC74_RS38585 4d99304f616bcd369eab37dceb669461 460 Gene3D G3DSA:3.80.30.20 55 274 4.9E-24 T 23-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe DC74_RS26310 cc53d2b0097e8c7032506a897b66e91f 139 PANTHER PTHR33202:SF7 1 139 2.1E-40 T 23-04-2016 DC74_RS26310 cc53d2b0097e8c7032506a897b66e91f 139 PANTHER PTHR33202 1 139 2.1E-40 T 23-04-2016 DC74_RS26310 cc53d2b0097e8c7032506a897b66e91f 139 Pfam PF01475 Ferric uptake regulator family 11 126 1.0E-25 T 23-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 DC74_RS26310 cc53d2b0097e8c7032506a897b66e91f 139 Gene3D G3DSA:1.10.10.10 2 82 7.0E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26310 cc53d2b0097e8c7032506a897b66e91f 139 SUPERFAMILY SSF46785 3 133 1.66E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34445 ee308c57379812bfec40eaf8b1c0e5d0 381 SUPERFAMILY SSF56112 21 324 1.43E-21 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS34445 ee308c57379812bfec40eaf8b1c0e5d0 381 Gene3D G3DSA:3.90.1200.10 182 312 1.2E-10 T 23-04-2016 DC74_RS34445 ee308c57379812bfec40eaf8b1c0e5d0 381 Pfam PF01636 Phosphotransferase enzyme family 63 306 3.8E-14 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 Gene3D G3DSA:3.30.460.10 281 427 6.0E-49 T 23-04-2016 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 SMART SM00471 146 256 1.1E-12 T 23-04-2016 IPR003607 HD/PDEase domain DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 SUPERFAMILY SSF109604 120 293 2.48E-71 T 23-04-2016 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 SUPERFAMILY SSF55021 762 843 1.62E-15 T 23-04-2016 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 SUPERFAMILY SSF81301 283 511 8.01E-63 T 23-04-2016 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 PANTHER PTHR21262 75 842 0.0 T 23-04-2016 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 Gene3D G3DSA:3.30.70.260 765 837 5.7E-15 T 23-04-2016 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 Pfam PF02824 TGS domain 507 566 1.2E-21 T 23-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 Pfam PF04607 Region found in RelA / SpoT proteins 338 447 3.8E-37 T 23-04-2016 IPR007685 RelA/SpoT GO:0015969 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 131 839 2.5E-257 T 23-04-2016 IPR004811 RelA/SpoT family GO:0015969 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 Gene3D G3DSA:3.10.20.30 506 568 4.3E-23 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 SUPERFAMILY SSF81271 494 566 3.71E-21 T 23-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 PANTHER PTHR21262:SF0 75 842 0.0 T 23-04-2016 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 Pfam PF13291 ACT domain 763 839 4.0E-17 T 23-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 SMART SM00954 338 448 2.1E-64 T 23-04-2016 IPR007685 RelA/SpoT GO:0015969 DC74_RS09585 047542b570ce6a9011bf5cf4a2cf6aaf 846 Pfam PF13328 HD domain 131 278 2.4E-51 T 23-04-2016 IPR003607 HD/PDEase domain DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 SMART SM01002 149 297 1.2E-80 T 23-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 23-04-2016 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 Gene3D G3DSA:3.40.50.1770 2 177 1.7E-57 T 23-04-2016 DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 SUPERFAMILY SSF52283 305 360 6.89E-68 T 23-04-2016 DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 SUPERFAMILY SSF52283 2 137 6.89E-68 T 23-04-2016 DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 2.1E-47 T 23-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.5E-81 T 23-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 SMART SM01003 4 137 1.0E-79 T 23-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 SUPERFAMILY SSF51735 137 303 5.16E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 Gene3D G3DSA:3.40.50.1770 194 356 7.6E-30 T 23-04-2016 DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 Gene3D G3DSA:3.50.50.60 178 193 5.8E-5 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 2 368 3.7E-175 T 23-04-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 PANTHER PTHR10160 2 364 1.3E-201 T 23-04-2016 DC74_RS11055 aa5ecdf3c25233eeb345747fb22e2650 371 PIRSF PIRSF000183 1 371 9.6E-168 T 23-04-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 Gene3D G3DSA:3.30.70.250 86 145 3.2E-6 T 23-04-2016 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1109 1124 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 SMART SM01294 1083 1150 4.6E-4 T 23-04-2016 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 PANTHER PTHR11712 1172 1227 6.0E-305 T 23-04-2016 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 SUPERFAMILY SSF51735 799 1015 8.78E-42 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 SMART SM00823 Phosphopantetheine attachment site 1082 1154 1.1E-28 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 PANTHER PTHR11712:SF242 1172 1227 6.0E-305 T 23-04-2016 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 Pfam PF08659 KR domain 801 978 7.2E-55 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 Gene3D G3DSA:3.40.50.720 800 1012 9.7E-31 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1 254 1.3E-85 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 SUPERFAMILY SSF52151 2 80 1.46E-62 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 SUPERFAMILY SSF52151 139 250 1.46E-62 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 Pfam PF00550 Phosphopantetheine attachment site 1085 1150 5.1E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 Gene3D G3DSA:1.10.1200.10 1079 1155 6.8E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 PANTHER PTHR11712:SF242 2 1150 6.0E-305 T 23-04-2016 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 SUPERFAMILY SSF47336 1074 1164 1.7E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 801 981 7.7E-57 T 23-04-2016 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 Pfam PF14765 Polyketide synthase dehydratase 322 572 8.3E-21 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 SMART SM00826 322 481 6.1E-45 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 Pfam PF00698 Acyl transferase domain 3 273 1.4E-46 T 23-04-2016 IPR014043 Acyl transferase DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 PANTHER PTHR11712 2 1150 6.0E-305 T 23-04-2016 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 SUPERFAMILY SSF55048 85 146 4.45E-9 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 SUPERFAMILY SSF51735 590 782 2.01E-31 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 Gene3D G3DSA:3.40.366.10 146 258 6.5E-66 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS38710 19fa98c322d07919ead44ef7b106d3a8 1241 Gene3D G3DSA:3.40.366.10 2 80 6.5E-66 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS27825 d96ee2732ee5bc1837610f998eee2711 140 PANTHER PTHR36222 1 140 5.7E-57 T 23-04-2016 DC74_RS27825 d96ee2732ee5bc1837610f998eee2711 140 Gene3D G3DSA:3.30.450.30 6 126 9.4E-26 T 23-04-2016 DC74_RS27825 d96ee2732ee5bc1837610f998eee2711 140 SMART SM00960 12 102 1.6E-33 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS27825 d96ee2732ee5bc1837610f998eee2711 140 SUPERFAMILY SSF103196 4 128 2.22E-32 T 23-04-2016 DC74_RS27825 d96ee2732ee5bc1837610f998eee2711 140 Pfam PF03259 Roadblock/LC7 domain 12 102 2.1E-26 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 471 750 25.237 T 23-04-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 187 431 5.6E-61 T 23-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 8 451 35.708 T 23-04-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 SUPERFAMILY SSF82866 566 748 3.53E-31 T 23-04-2016 DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 499 739 2.6E-60 T 23-04-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 SUPERFAMILY SSF82866 243 438 1.96E-34 T 23-04-2016 DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 36 437 1.4E-108 T 23-04-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 PRINTS PR01755 Bacterial translocase SecF protein signature 607 621 8.1E-22 T 23-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 PRINTS PR01755 Bacterial translocase SecF protein signature 498 513 8.1E-22 T 23-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 PRINTS PR01755 Bacterial translocase SecF protein signature 687 702 8.1E-22 T 23-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 PRINTS PR01755 Bacterial translocase SecF protein signature 655 673 8.1E-22 T 23-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 Pfam PF02355 Protein export membrane protein 268 437 3.4E-15 T 23-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 Pfam PF02355 Protein export membrane protein 568 747 1.2E-61 T 23-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 PANTHER PTHR30081 149 472 5.3E-99 T 23-04-2016 DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 PANTHER PTHR30081 13 118 5.3E-99 T 23-04-2016 DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 Pfam PF07549 SecD/SecF GG Motif 495 520 1.0E-5 T 23-04-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 Pfam PF07549 SecD/SecF GG Motif 30 50 1.5E-4 T 23-04-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 Gene3D G3DSA:1.20.1640.10 262 439 6.9E-23 T 23-04-2016 DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 Gene3D G3DSA:1.20.1640.10 585 756 1.4E-21 T 23-04-2016 DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 PANTHER PTHR30081:SF1 149 472 5.3E-99 T 23-04-2016 DC74_RS02670 27f6905eccec8959a1d9c4877c7b2158 777 PANTHER PTHR30081:SF1 13 118 5.3E-99 T 23-04-2016 DC74_RS22120 53c9ef875305b6ddce17e019b5af46f7 385 SUPERFAMILY SSF52540 38 337 1.4E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22120 53c9ef875305b6ddce17e019b5af46f7 385 Gene3D G3DSA:3.30.450.90 53 148 3.4E-28 T 23-04-2016 DC74_RS22120 53c9ef875305b6ddce17e019b5af46f7 385 PANTHER PTHR30258 25 374 5.7E-154 T 23-04-2016 DC74_RS22120 53c9ef875305b6ddce17e019b5af46f7 385 PANTHER PTHR30258:SF12 25 374 5.7E-154 T 23-04-2016 DC74_RS22120 53c9ef875305b6ddce17e019b5af46f7 385 Gene3D G3DSA:3.40.50.300 156 371 1.8E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22120 53c9ef875305b6ddce17e019b5af46f7 385 Pfam PF00437 Type II/IV secretion system protein 56 331 9.7E-79 T 23-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 DC74_RS22120 53c9ef875305b6ddce17e019b5af46f7 385 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 6 343 1.8E-158 T 23-04-2016 IPR022399 Helicase/secretion neighbourhood ATPase DC74_RS21255 18c4d6db49090cf34a45e63745856f5e 380 Pfam PF13421 SPFH domain-Band 7 family 26 237 3.7E-98 T 23-04-2016 DC74_RS21255 18c4d6db49090cf34a45e63745856f5e 380 Pfam PF14237 Domain of unknown function (DUF4339) 316 358 1.1E-12 T 23-04-2016 IPR025640 Domain of unknown function DUF4339 DC74_RS21255 18c4d6db49090cf34a45e63745856f5e 380 SUPERFAMILY SSF117892 124 232 2.09E-6 T 23-04-2016 IPR001107 Band 7 domain DC74_RS21255 18c4d6db49090cf34a45e63745856f5e 380 PANTHER PTHR37826 1 366 4.1E-111 T 23-04-2016 DC74_RS21255 18c4d6db49090cf34a45e63745856f5e 380 PANTHER PTHR37826:SF2 1 366 4.1E-111 T 23-04-2016 DC74_RS31610 8030902ab876830132aa0299e87c939c 184 SUPERFAMILY SSF52499 7 183 8.5E-50 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS31610 8030902ab876830132aa0299e87c939c 184 Gene3D G3DSA:3.40.50.850 9 180 1.4E-50 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS31610 8030902ab876830132aa0299e87c939c 184 PANTHER PTHR11080:SF37 9 183 2.5E-50 T 23-04-2016 DC74_RS31610 8030902ab876830132aa0299e87c939c 184 PANTHER PTHR11080 9 183 2.5E-50 T 23-04-2016 DC74_RS31610 8030902ab876830132aa0299e87c939c 184 Pfam PF00857 Isochorismatase family 10 177 7.0E-42 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 PIRSF PIRSF000724 1 403 3.4E-129 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 403 39.75 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 PANTHER PTHR11406 2 403 2.3E-183 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 SUPERFAMILY SSF53748 3 403 2.0E-137 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 PRINTS PR00477 Phosphoglycerate kinase family signature 355 366 7.59E-78 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 7.59E-78 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 PRINTS PR00477 Phosphoglycerate kinase family signature 11 27 7.59E-78 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 7.59E-78 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 7.59E-78 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 PRINTS PR00477 Phosphoglycerate kinase family signature 379 396 7.59E-78 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 7.59E-78 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 PRINTS PR00477 Phosphoglycerate kinase family signature 322 347 7.59E-78 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 7.59E-78 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 Gene3D G3DSA:3.40.50.1270 185 391 5.9E-77 T 23-04-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 Gene3D G3DSA:3.40.50.1260 2 184 2.9E-62 T 23-04-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 Pfam PF00162 Phosphoglycerate kinase 12 393 5.4E-142 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS11825 3d115bbc2b54f51ef4cb19480185566c 403 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 16 26 - T 23-04-2016 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 DC74_RS06275 0d794991bd1510d8ece1976622137a1d 428 SMART SM00382 195 329 5.3E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS06275 0d794991bd1510d8ece1976622137a1d 428 PANTHER PTHR23077 18 25 7.9E-40 T 23-04-2016 DC74_RS06275 0d794991bd1510d8ece1976622137a1d 428 PANTHER PTHR23077 155 417 7.9E-40 T 23-04-2016 DC74_RS06275 0d794991bd1510d8ece1976622137a1d 428 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 199 325 2.1E-25 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS06275 0d794991bd1510d8ece1976622137a1d 428 Pfam PF00583 Acetyltransferase (GNAT) family 52 124 4.1E-7 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS06275 0d794991bd1510d8ece1976622137a1d 428 Gene3D G3DSA:3.40.630.30 5 128 7.8E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06275 0d794991bd1510d8ece1976622137a1d 428 SUPERFAMILY SSF52540 160 380 1.04E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06275 0d794991bd1510d8ece1976622137a1d 428 ProSitePatterns PS00674 AAA-protein family signature. 297 315 - T 23-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DC74_RS06275 0d794991bd1510d8ece1976622137a1d 428 SUPERFAMILY SSF55729 1 135 1.3E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06275 0d794991bd1510d8ece1976622137a1d 428 Gene3D G3DSA:3.40.50.300 161 380 3.4E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 870 884 2.6E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 900 912 2.6E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 884 900 2.6E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 SUPERFAMILY SSF46894 862 923 8.16E-16 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 Gene3D G3DSA:1.25.40.10 743 812 1.3E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 Gene3D G3DSA:1.25.40.10 390 428 1.3E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 Gene3D G3DSA:1.25.40.10 633 678 1.3E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 PANTHER PTHR16305 783 848 2.7E-25 T 23-04-2016 DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 PANTHER PTHR16305 2 429 2.7E-25 T 23-04-2016 DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 Gene3D G3DSA:1.10.10.10 864 922 3.0E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 Pfam PF13191 AAA ATPase domain 2 164 7.5E-21 T 23-04-2016 DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 SUPERFAMILY SSF52540 131 236 3.2E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 SUPERFAMILY SSF52540 3 83 3.2E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 SMART SM00421 867 924 1.2E-17 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 Pfam PF00196 Bacterial regulatory proteins, luxR family 869 922 5.3E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38775 0d00b60eede0ccbea3f88d0a0fed1053 927 Gene3D G3DSA:3.40.50.300 13 58 3.8E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32835 99e1d8714589a9c42096b0841ef19cd6 272 Pfam PF04672 S-adenosyl methyltransferase 9 271 1.6E-102 T 23-04-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type DC74_RS32835 99e1d8714589a9c42096b0841ef19cd6 272 SUPERFAMILY SSF53335 17 250 8.77E-47 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS32835 99e1d8714589a9c42096b0841ef19cd6 272 PIRSF PIRSF017393 1 272 9.3E-101 T 23-04-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type DC74_RS32835 99e1d8714589a9c42096b0841ef19cd6 272 Gene3D G3DSA:3.40.50.150 3 272 2.8E-108 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS04680 6974d93a9efdf34fd25c3736d0e06535 323 SMART SM00342 240 323 1.8E-22 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS04680 6974d93a9efdf34fd25c3736d0e06535 323 PANTHER PTHR11019 94 321 3.1E-18 T 23-04-2016 DC74_RS04680 6974d93a9efdf34fd25c3736d0e06535 323 Gene3D G3DSA:1.10.10.60 222 276 4.9E-5 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04680 6974d93a9efdf34fd25c3736d0e06535 323 SUPERFAMILY SSF46689 276 323 3.82E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04680 6974d93a9efdf34fd25c3736d0e06535 323 Gene3D G3DSA:1.10.10.60 277 323 2.8E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04680 6974d93a9efdf34fd25c3736d0e06535 323 Pfam PF14525 AraC-binding-like domain 93 208 3.9E-7 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS04680 6974d93a9efdf34fd25c3736d0e06535 323 Pfam PF12833 Helix-turn-helix domain 246 321 2.5E-22 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS26870 2578c1850112b4143747934f94112368 374 PANTHER PTHR33392:SF7 13 360 8.5E-111 T 23-04-2016 DC74_RS26870 2578c1850112b4143747934f94112368 374 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 111 268 7.8E-49 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS26870 2578c1850112b4143747934f94112368 374 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 110 268 2.4E-55 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS26870 2578c1850112b4143747934f94112368 374 PANTHER PTHR33392 13 360 8.5E-111 T 23-04-2016 DC74_RS38460 2ec1f06d04a1618b58688899681993d8 265 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 224 256 9.8E-8 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS38460 2ec1f06d04a1618b58688899681993d8 265 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS38460 2ec1f06d04a1618b58688899681993d8 265 PANTHER PTHR24220 7 256 1.1E-102 T 23-04-2016 DC74_RS38460 2ec1f06d04a1618b58688899681993d8 265 SUPERFAMILY SSF52540 3 251 2.21E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38460 2ec1f06d04a1618b58688899681993d8 265 Pfam PF00005 ABC transporter 22 172 2.3E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS38460 2ec1f06d04a1618b58688899681993d8 265 Gene3D G3DSA:3.40.50.300 3 251 3.7E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38460 2ec1f06d04a1618b58688899681993d8 265 PANTHER PTHR24220:SF336 7 256 1.1E-102 T 23-04-2016 DC74_RS38460 2ec1f06d04a1618b58688899681993d8 265 SMART SM00382 30 222 8.7E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS23730 1d83d6627b01b6f99b9747981e197082 537 SUPERFAMILY SSF55874 234 357 4.98E-18 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23730 1d83d6627b01b6f99b9747981e197082 537 Gene3D G3DSA:3.30.565.10 232 359 1.0E-15 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23730 1d83d6627b01b6f99b9747981e197082 537 PANTHER PTHR24423 72 421 1.1E-22 T 23-04-2016 DC74_RS23730 1d83d6627b01b6f99b9747981e197082 537 PANTHER PTHR24423:SF508 72 421 1.1E-22 T 23-04-2016 DC74_RS23730 1d83d6627b01b6f99b9747981e197082 537 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 250 356 1.6E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23730 1d83d6627b01b6f99b9747981e197082 537 SMART SM00387 247 358 1.6E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01785 c2cf526d0d06155168c99f3c5a3ae0fd 278 Pfam PF02311 AraC-like ligand binding domain 17 139 3.8E-20 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS01785 c2cf526d0d06155168c99f3c5a3ae0fd 278 Pfam PF12833 Helix-turn-helix domain 186 262 3.8E-21 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS01785 c2cf526d0d06155168c99f3c5a3ae0fd 278 Gene3D G3DSA:2.60.120.280 21 136 2.6E-6 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS01785 c2cf526d0d06155168c99f3c5a3ae0fd 278 Gene3D G3DSA:1.10.10.60 218 262 1.2E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01785 c2cf526d0d06155168c99f3c5a3ae0fd 278 SUPERFAMILY SSF51215 21 138 2.22E-10 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS01785 c2cf526d0d06155168c99f3c5a3ae0fd 278 Gene3D G3DSA:1.10.10.60 161 217 6.5E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01785 c2cf526d0d06155168c99f3c5a3ae0fd 278 PANTHER PTHR11019:SF75 4 269 4.1E-77 T 23-04-2016 DC74_RS01785 c2cf526d0d06155168c99f3c5a3ae0fd 278 PANTHER PTHR11019 4 269 4.1E-77 T 23-04-2016 DC74_RS01785 c2cf526d0d06155168c99f3c5a3ae0fd 278 SUPERFAMILY SSF46689 215 262 1.97E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01785 c2cf526d0d06155168c99f3c5a3ae0fd 278 SUPERFAMILY SSF46689 166 213 2.96E-6 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01785 c2cf526d0d06155168c99f3c5a3ae0fd 278 SMART SM00342 179 261 2.1E-26 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS23875 7dc8f4894f430852d6f07129b7b5b08a 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 381 1.3E-29 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS23875 7dc8f4894f430852d6f07129b7b5b08a 391 SUPERFAMILY SSF47203 232 389 1.39E-37 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS23875 7dc8f4894f430852d6f07129b7b5b08a 391 SUPERFAMILY SSF56645 10 247 4.58E-61 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS23875 7dc8f4894f430852d6f07129b7b5b08a 391 Gene3D G3DSA:1.10.540.10 12 122 9.1E-31 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS23875 7dc8f4894f430852d6f07129b7b5b08a 391 PANTHER PTHR10909 8 391 2.8E-116 T 23-04-2016 DC74_RS23875 7dc8f4894f430852d6f07129b7b5b08a 391 PANTHER PTHR10909:SF121 8 391 2.8E-116 T 23-04-2016 DC74_RS23875 7dc8f4894f430852d6f07129b7b5b08a 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 122 6.6E-29 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS23875 7dc8f4894f430852d6f07129b7b5b08a 391 Gene3D G3DSA:1.20.140.10 225 390 2.3E-46 T 23-04-2016 DC74_RS23875 7dc8f4894f430852d6f07129b7b5b08a 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 220 6.7E-17 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS23875 7dc8f4894f430852d6f07129b7b5b08a 391 Gene3D G3DSA:2.40.110.10 127 224 9.6E-26 T 23-04-2016 DC74_RS11150 f29dd35d66264fd2053dc3e0247ece7b 296 Gene3D G3DSA:2.40.30.10 10 142 2.5E-33 T 23-04-2016 DC74_RS11150 f29dd35d66264fd2053dc3e0247ece7b 296 PANTHER PTHR30157 11 286 1.7E-91 T 23-04-2016 DC74_RS11150 f29dd35d66264fd2053dc3e0247ece7b 296 SUPERFAMILY SSF63380 10 142 3.78E-10 T 23-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 DC74_RS11150 f29dd35d66264fd2053dc3e0247ece7b 296 Gene3D G3DSA:3.40.50.80 152 282 3.5E-49 T 23-04-2016 DC74_RS11150 f29dd35d66264fd2053dc3e0247ece7b 296 PANTHER PTHR30157:SF0 11 286 1.7E-91 T 23-04-2016 DC74_RS11150 f29dd35d66264fd2053dc3e0247ece7b 296 Pfam PF04954 Siderophore-interacting protein 158 276 1.2E-40 T 23-04-2016 IPR007037 Siderophore-interacting protein DC74_RS11150 f29dd35d66264fd2053dc3e0247ece7b 296 Pfam PF08021 Siderophore-interacting FAD-binding domain 18 144 1.5E-36 T 23-04-2016 IPR013113 FAD-binding 9, siderophore-interacting DC74_RS18645 163b92e9229734500acc1f84994b8531 151 Gene3D G3DSA:3.100.10.10 37 150 6.3E-31 T 23-04-2016 DC74_RS18645 163b92e9229734500acc1f84994b8531 151 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 9 150 18.364 T 23-04-2016 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 DC74_RS18645 163b92e9229734500acc1f84994b8531 151 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 32 148 1.3E-31 T 23-04-2016 IPR021131 Ribosomal protein L18e/L15P DC74_RS18645 163b92e9229734500acc1f84994b8531 151 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 8 147 8.1E-44 T 23-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 DC74_RS18645 163b92e9229734500acc1f84994b8531 151 SUPERFAMILY SSF52080 10 148 3.92E-39 T 23-04-2016 IPR021131 Ribosomal protein L18e/L15P DC74_RS18645 163b92e9229734500acc1f84994b8531 151 ProSitePatterns PS00475 Ribosomal protein L15 signature. 114 144 - T 23-04-2016 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS32490 f4db86a268a20532b55aff51d761f620 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 106 2.0E-6 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS32490 f4db86a268a20532b55aff51d761f620 128 SUPERFAMILY SSF54593 5 112 6.46E-24 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS32490 f4db86a268a20532b55aff51d761f620 128 Gene3D G3DSA:3.10.180.10 2 113 2.4E-31 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS09040 f3edc721b67268965bd7e0c0e5cd2b2f 287 Gene3D G3DSA:1.10.260.40 6 83 7.9E-19 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS09040 f3edc721b67268965bd7e0c0e5cd2b2f 287 Pfam PF13560 Helix-turn-helix domain 8 86 3.0E-16 T 23-04-2016 DC74_RS09040 f3edc721b67268965bd7e0c0e5cd2b2f 287 SUPERFAMILY SSF47413 32 80 1.65E-6 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS09040 f3edc721b67268965bd7e0c0e5cd2b2f 287 SMART SM00530 12 84 1.6E-5 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS09040 f3edc721b67268965bd7e0c0e5cd2b2f 287 PANTHER PTHR35010 7 283 4.6E-100 T 23-04-2016 DC74_RS09040 f3edc721b67268965bd7e0c0e5cd2b2f 287 PANTHER PTHR35010:SF2 7 283 4.6E-100 T 23-04-2016 DC74_RS02585 f386433cce026741350462afd1068532 301 SUPERFAMILY SSF53850 92 295 6.19E-40 T 23-04-2016 DC74_RS02585 f386433cce026741350462afd1068532 301 Gene3D G3DSA:1.10.10.10 3 88 3.3E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02585 f386433cce026741350462afd1068532 301 Gene3D G3DSA:3.40.190.10 91 184 4.6E-20 T 23-04-2016 DC74_RS02585 f386433cce026741350462afd1068532 301 Pfam PF03466 LysR substrate binding domain 90 291 7.0E-41 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS02585 f386433cce026741350462afd1068532 301 PANTHER PTHR30346 1 293 1.1E-94 T 23-04-2016 DC74_RS02585 f386433cce026741350462afd1068532 301 Gene3D G3DSA:3.40.190.10 185 263 3.6E-13 T 23-04-2016 DC74_RS02585 f386433cce026741350462afd1068532 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.7E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS02585 f386433cce026741350462afd1068532 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.7E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS02585 f386433cce026741350462afd1068532 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.7E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS02585 f386433cce026741350462afd1068532 301 SUPERFAMILY SSF46785 2 113 2.27E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02585 f386433cce026741350462afd1068532 301 PANTHER PTHR30346:SF3 1 293 1.1E-94 T 23-04-2016 DC74_RS02585 f386433cce026741350462afd1068532 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.0E-26 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 SUPERFAMILY SSF55073 164 309 7.85E-9 T 23-04-2016 IPR029787 Nucleotide cyclase DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 Pfam PF13641 Glycosyltransferase like family 2 413 637 3.3E-27 T 23-04-2016 DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 SUPERFAMILY SSF53448 402 671 9.23E-33 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 SMART SM00267 141 318 4.3E-4 T 23-04-2016 IPR000160 GGDEF domain DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 PANTHER PTHR10587:SF64 619 625 1.9E-29 T 23-04-2016 DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 Gene3D G3DSA:3.30.70.270 160 318 2.3E-10 T 23-04-2016 DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 Gene3D G3DSA:3.40.50.2300 24 150 3.2E-10 T 23-04-2016 DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 Pfam PF00990 Diguanylate cyclase, GGDEF domain 160 309 7.1E-5 T 23-04-2016 IPR000160 GGDEF domain DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 PANTHER PTHR10587 376 581 1.9E-29 T 23-04-2016 DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 PANTHER PTHR10587 619 625 1.9E-29 T 23-04-2016 DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 Gene3D G3DSA:3.90.550.10 416 652 1.5E-18 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 SUPERFAMILY SSF52172 30 157 1.15E-12 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS31025 4fa9b8d9f4ca42ef403d1a6a2909dddc 790 PANTHER PTHR10587:SF64 376 581 1.9E-29 T 23-04-2016 DC74_RS11030 a6af7d213079d0e200d09b372b0dc115 370 SUPERFAMILY SSF55120 179 368 1.09E-42 T 23-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS11030 a6af7d213079d0e200d09b372b0dc115 370 Pfam PF00849 RNA pseudouridylate synthase 196 326 3.4E-23 T 23-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 DC74_RS11030 a6af7d213079d0e200d09b372b0dc115 370 Pfam PF01479 S4 domain 134 180 4.6E-13 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS11030 a6af7d213079d0e200d09b372b0dc115 370 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 199 357 9.3E-43 T 23-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 DC74_RS11030 a6af7d213079d0e200d09b372b0dc115 370 SUPERFAMILY SSF55174 126 198 9.03E-13 T 23-04-2016 DC74_RS11030 a6af7d213079d0e200d09b372b0dc115 370 SMART SM00363 134 195 5.5E-9 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS11030 a6af7d213079d0e200d09b372b0dc115 370 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 232 246 - T 23-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 DC74_RS11030 a6af7d213079d0e200d09b372b0dc115 370 Gene3D G3DSA:3.10.290.10 132 192 6.7E-22 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS11030 a6af7d213079d0e200d09b372b0dc115 370 PANTHER PTHR21600 130 370 9.9E-79 T 23-04-2016 DC74_RS11030 a6af7d213079d0e200d09b372b0dc115 370 PANTHER PTHR21600:SF2 130 370 9.9E-79 T 23-04-2016 DC74_RS30900 a8db1fa415a8f5d4ac02b66e551f8571 268 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 110 138 - T 23-04-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 DC74_RS30900 a8db1fa415a8f5d4ac02b66e551f8571 268 PANTHER PTHR33711:SF1 51 268 4.3E-95 T 23-04-2016 DC74_RS30900 a8db1fa415a8f5d4ac02b66e551f8571 268 Pfam PF00775 Dioxygenase 79 258 6.7E-52 T 23-04-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 DC74_RS30900 a8db1fa415a8f5d4ac02b66e551f8571 268 PANTHER PTHR33711 51 268 4.3E-95 T 23-04-2016 DC74_RS30900 a8db1fa415a8f5d4ac02b66e551f8571 268 SUPERFAMILY SSF49482 76 265 1.83E-61 T 23-04-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 DC74_RS30900 a8db1fa415a8f5d4ac02b66e551f8571 268 Gene3D G3DSA:2.60.130.10 73 265 2.5E-69 T 23-04-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 DC74_RS29395 d4bbd6373539c2359f9fcbffaf0a0125 535 Gene3D G3DSA:3.30.300.30 431 532 1.3E-31 T 23-04-2016 DC74_RS29395 d4bbd6373539c2359f9fcbffaf0a0125 535 Gene3D G3DSA:3.40.50.980 200 352 1.1E-31 T 23-04-2016 DC74_RS29395 d4bbd6373539c2359f9fcbffaf0a0125 535 PANTHER PTHR24095 34 535 1.2E-140 T 23-04-2016 DC74_RS29395 d4bbd6373539c2359f9fcbffaf0a0125 535 Gene3D G3DSA:3.40.50.980 47 199 2.8E-29 T 23-04-2016 DC74_RS29395 d4bbd6373539c2359f9fcbffaf0a0125 535 Pfam PF00501 AMP-binding enzyme 50 436 3.3E-78 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS29395 d4bbd6373539c2359f9fcbffaf0a0125 535 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 523 2.8E-24 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS29395 d4bbd6373539c2359f9fcbffaf0a0125 535 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS29395 d4bbd6373539c2359f9fcbffaf0a0125 535 SUPERFAMILY SSF56801 24 534 2.49E-134 T 23-04-2016 DC74_RS29395 d4bbd6373539c2359f9fcbffaf0a0125 535 Gene3D G3DSA:2.30.38.10 355 427 2.5E-16 T 23-04-2016 DC74_RS11210 3cf0f9fe77c5d9045de5db36b439cbc9 216 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 13 198 1.7E-59 T 23-04-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 DC74_RS11210 3cf0f9fe77c5d9045de5db36b439cbc9 216 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 12 201 33.304 T 23-04-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 DC74_RS11210 3cf0f9fe77c5d9045de5db36b439cbc9 216 Gene3D G3DSA:3.10.300.10 8 210 2.2E-65 T 23-04-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 DC74_RS11210 3cf0f9fe77c5d9045de5db36b439cbc9 216 SUPERFAMILY SSF50486 8 207 4.0E-58 T 23-04-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 DC74_RS11210 3cf0f9fe77c5d9045de5db36b439cbc9 216 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 10 201 1.7E-47 T 23-04-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 DC74_RS11210 3cf0f9fe77c5d9045de5db36b439cbc9 216 PANTHER PTHR10429:SF0 3 216 1.0E-64 T 23-04-2016 DC74_RS11210 3cf0f9fe77c5d9045de5db36b439cbc9 216 PANTHER PTHR10429 3 216 1.0E-64 T 23-04-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 DC74_RS24770 1eed9440693fcebe42e63b16e784f5cb 273 SUPERFAMILY SSF53474 18 269 1.26E-51 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS24770 1eed9440693fcebe42e63b16e784f5cb 273 Gene3D G3DSA:3.40.50.1820 18 269 2.0E-51 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS24770 1eed9440693fcebe42e63b16e784f5cb 273 PANTHER PTHR10992 17 270 2.5E-40 T 23-04-2016 DC74_RS24770 1eed9440693fcebe42e63b16e784f5cb 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 4.4E-11 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS24770 1eed9440693fcebe42e63b16e784f5cb 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 215 229 4.4E-11 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS24770 1eed9440693fcebe42e63b16e784f5cb 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 4.4E-11 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS24770 1eed9440693fcebe42e63b16e784f5cb 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 4.4E-11 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS24770 1eed9440693fcebe42e63b16e784f5cb 273 Pfam PF00561 alpha/beta hydrolase fold 30 255 1.2E-24 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 PANTHER PTHR11482 8 438 4.9E-162 T 23-04-2016 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 PANTHER PTHR11482:SF45 8 438 4.9E-162 T 23-04-2016 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 343 401 2.5E-8 T 23-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 48 288 1.4E-37 T 23-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 SUPERFAMILY SSF50621 254 402 4.19E-31 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 230 245 - T 23-04-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Reactome: REACT_13 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 79 91 1.3E-11 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 383 396 1.3E-11 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 59 77 1.3E-11 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 192 205 1.3E-11 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 278 297 1.3E-11 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 Gene3D G3DSA:2.40.37.10 275 429 4.3E-35 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 Gene3D G3DSA:3.20.20.10 33 274 8.3E-60 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS17250 cd0214e84316d571a374c47a145a2287 444 SUPERFAMILY SSF51419 30 291 1.6E-53 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS03565 f2ad3707f19ea0bb935ad63ce9b97e95 442 PANTHER PTHR21015:SF21 13 392 1.8E-58 T 23-04-2016 DC74_RS03565 f2ad3707f19ea0bb935ad63ce9b97e95 442 Gene3D G3DSA:3.40.50.2000 189 354 2.9E-22 T 23-04-2016 DC74_RS03565 f2ad3707f19ea0bb935ad63ce9b97e95 442 SUPERFAMILY SSF53756 137 355 1.95E-15 T 23-04-2016 DC74_RS03565 f2ad3707f19ea0bb935ad63ce9b97e95 442 Pfam PF13692 Glycosyl transferases group 1 236 317 2.8E-6 T 23-04-2016 DC74_RS03565 f2ad3707f19ea0bb935ad63ce9b97e95 442 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 36 181 1.9E-8 T 23-04-2016 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 DC74_RS03565 f2ad3707f19ea0bb935ad63ce9b97e95 442 PANTHER PTHR21015 13 392 1.8E-58 T 23-04-2016 DC74_RS33710 288978ec39a9dbd02cba0c5f4a1eb30c 251 SUPERFAMILY SSF56235 2 244 2.44E-17 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS33710 288978ec39a9dbd02cba0c5f4a1eb30c 251 Pfam PF13522 Glutamine amidotransferase domain 75 216 7.6E-15 T 23-04-2016 DC74_RS33710 288978ec39a9dbd02cba0c5f4a1eb30c 251 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 246 9.8E-86 T 23-04-2016 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 DC74_RS33710 288978ec39a9dbd02cba0c5f4a1eb30c 251 Gene3D G3DSA:3.60.20.10 1 245 2.0E-35 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS33710 288978ec39a9dbd02cba0c5f4a1eb30c 251 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 246 40.472 T 23-04-2016 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 KEGG: 00311+3.5.1.11|KEGG: 00340+3.5.1.118|MetaCyc: PWY-7255|UniPathway: UPA01014 DC74_RS33710 288978ec39a9dbd02cba0c5f4a1eb30c 251 PANTHER PTHR11907 1 249 4.1E-118 T 23-04-2016 DC74_RS33710 288978ec39a9dbd02cba0c5f4a1eb30c 251 PANTHER PTHR11907:SF5 1 249 4.1E-118 T 23-04-2016 DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 SMART SM00564 579 615 6.0 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 SMART SM00564 421 455 45.0 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 SMART SM00564 501 532 0.0037 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 SMART SM00564 378 409 0.071 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 SMART SM00564 542 574 10.0 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 SMART SM00564 626 660 0.0043 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 SMART SM00564 463 493 0.0015 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 SMART SM00564 669 695 640.0 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 SMART SM00220 10 267 8.9E-60 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 Gene3D G3DSA:1.10.510.10 80 262 1.2E-47 T 23-04-2016 DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 SUPERFAMILY SSF50998 368 453 5.3E-8 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 PANTHER PTHR24362:SF160 3 270 3.5E-85 T 23-04-2016 DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 Gene3D G3DSA:3.30.200.20 3 79 1.2E-22 T 23-04-2016 DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 Gene3D G3DSA:2.140.10.10 461 693 2.9E-37 T 23-04-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 Gene3D G3DSA:2.140.10.10 362 460 3.2E-9 T 23-04-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 Pfam PF13360 PQQ-like domain 543 693 8.3E-17 T 23-04-2016 IPR002372 Pyrrolo-quinoline quinone repeat DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 Pfam PF00069 Protein kinase domain 10 261 1.5E-48 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 SUPERFAMILY SSF50998 450 692 7.85E-33 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 PANTHER PTHR24362 3 270 3.5E-85 T 23-04-2016 DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 Pfam PF13570 PQQ-like domain 486 524 2.8E-8 T 23-04-2016 IPR025666 Pyrrolo-quinoline quinone-like domain DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 Pfam PF13570 PQQ-like domain 363 401 7.7E-4 T 23-04-2016 IPR025666 Pyrrolo-quinoline quinone-like domain DC74_RS40640 e3b6b34b7678e5361563c887e7750864 696 SUPERFAMILY SSF56112 4 300 4.26E-68 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS38590 827611aef4373e74d5c28b1c1106d9ed 301 SUPERFAMILY SSF103481 185 287 1.83E-16 T 23-04-2016 DC74_RS38590 827611aef4373e74d5c28b1c1106d9ed 301 PANTHER PTHR22911 4 295 4.4E-42 T 23-04-2016 DC74_RS38590 827611aef4373e74d5c28b1c1106d9ed 301 SUPERFAMILY SSF103481 38 140 7.98E-12 T 23-04-2016 DC74_RS38590 827611aef4373e74d5c28b1c1106d9ed 301 Pfam PF00892 EamA-like transporter family 3 137 5.9E-15 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS38590 827611aef4373e74d5c28b1c1106d9ed 301 Pfam PF00892 EamA-like transporter family 148 281 4.1E-17 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 SUPERFAMILY SSF48264 19 399 4.19E-92 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PANTHER PTHR24286:SF42 25 401 1.0E-84 T 23-04-2016 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00359 B-class P450 signature 338 347 3.9E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00359 B-class P450 signature 196 218 3.9E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00359 B-class P450 signature 142 158 3.9E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00359 B-class P450 signature 289 316 3.9E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00359 B-class P450 signature 272 283 3.9E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00359 B-class P450 signature 347 358 3.9E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00359 B-class P450 signature 95 106 3.9E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00359 B-class P450 signature 317 332 3.9E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00359 B-class P450 signature 159 174 3.9E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 Pfam PF00067 Cytochrome P450 198 369 7.5E-26 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PANTHER PTHR24286 25 401 1.0E-84 T 23-04-2016 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 Gene3D G3DSA:1.10.630.10 18 400 2.0E-118 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00385 P450 superfamily signature 347 358 2.7E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00385 P450 superfamily signature 237 254 2.7E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00385 P450 superfamily signature 272 283 2.7E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS30265 aa8c2ef4d98a835890f63dfaebf355fc 401 PRINTS PR00385 P450 superfamily signature 338 347 2.7E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS09220 45630163eed89463f10787d1d6b3f62e 219 PANTHER PTHR36122:SF1 1 218 1.2E-67 T 23-04-2016 DC74_RS09220 45630163eed89463f10787d1d6b3f62e 219 Pfam PF04973 Nicotinamide mononucleotide transporter 21 201 1.7E-41 T 23-04-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 DC74_RS09220 45630163eed89463f10787d1d6b3f62e 219 PANTHER PTHR36122 1 218 1.2E-67 T 23-04-2016 DC74_RS03695 69afd6fc3a64ba4882de04a670005683 352 PANTHER PTHR30595 1 346 2.3E-51 T 23-04-2016 DC74_RS03695 69afd6fc3a64ba4882de04a670005683 352 Pfam PF08279 HTH domain 7 62 7.9E-7 T 23-04-2016 IPR013196 Helix-turn-helix, type 11 DC74_RS03695 69afd6fc3a64ba4882de04a670005683 352 Gene3D G3DSA:1.10.10.10 4 66 1.4E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03695 69afd6fc3a64ba4882de04a670005683 352 SUPERFAMILY SSF46785 6 61 1.97E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03695 69afd6fc3a64ba4882de04a670005683 352 Pfam PF13280 WYL domain 144 346 1.2E-30 T 23-04-2016 IPR026881 WYL domain DC74_RS03695 69afd6fc3a64ba4882de04a670005683 352 PANTHER PTHR30595:SF4 1 346 2.3E-51 T 23-04-2016 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 SUPERFAMILY SSF50465 305 397 4.8E-36 T 23-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.053 T 23-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 Gene3D G3DSA:3.40.50.300 5 213 5.0E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 Pfam PF03143 Elongation factor Tu C-terminal domain 302 395 4.1E-33 T 23-04-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 23-04-2016 IPR031157 Tr-type G domain, conserved site DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 Gene3D G3DSA:2.40.30.10 214 301 5.6E-36 T 23-04-2016 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 Pfam PF03144 Elongation factor Tu domain 2 227 295 1.9E-16 T 23-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.1E-24 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.1E-24 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.1E-24 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.1E-24 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.1E-24 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 SUPERFAMILY SSF52540 6 221 1.43E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 SUPERFAMILY SSF50447 207 304 2.5E-30 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 Gene3D G3DSA:2.40.30.10 303 395 1.1E-45 T 23-04-2016 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 5.3E-217 T 23-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 PANTHER PTHR23115 1 397 1.8E-244 T 23-04-2016 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 2.8E-57 T 23-04-2016 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 PANTHER PTHR23115:SF112 1 397 1.8E-244 T 23-04-2016 DC74_RS00125 c8fe6a56dcd35949f57266987c0693bf 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 150 4.4E-14 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 Gene3D G3DSA:3.20.20.80 743 768 1.7E-75 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 Gene3D G3DSA:3.20.20.80 583 700 1.7E-75 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 Gene3D G3DSA:3.20.20.80 236 536 1.7E-75 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 SUPERFAMILY SSF81296 126 223 5.6E-19 T 23-04-2016 IPR014756 Immunoglobulin E-set DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 Pfam PF11852 Domain of unknown function (DUF3372) 711 859 3.2E-45 T 23-04-2016 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 128 206 1.8E-8 T 23-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 13 861 8.2E-284 T 23-04-2016 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 Gene3D G3DSA:2.60.40.10 129 220 1.5E-15 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 PANTHER PTHR10357:SF99 334 500 4.9E-200 T 23-04-2016 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 PANTHER PTHR10357:SF99 67 91 4.9E-200 T 23-04-2016 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 PANTHER PTHR10357:SF99 746 861 4.9E-200 T 23-04-2016 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 PANTHER PTHR10357:SF99 519 722 4.9E-200 T 23-04-2016 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 PANTHER PTHR10357:SF99 110 307 4.9E-200 T 23-04-2016 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 SUPERFAMILY SSF51445 218 767 5.16E-117 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 SUPERFAMILY SSF81296 7 118 1.54E-18 T 23-04-2016 IPR014756 Immunoglobulin E-set DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 PANTHER PTHR10357 334 500 4.9E-200 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 PANTHER PTHR10357 67 91 4.9E-200 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 PANTHER PTHR10357 746 861 4.9E-200 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 PANTHER PTHR10357 519 722 4.9E-200 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 PANTHER PTHR10357 110 307 4.9E-200 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS13225 70c4e747a0386544c2b05b4961c1e5d7 862 SUPERFAMILY SSF51011 772 860 1.29E-23 T 23-04-2016 DC74_RS38515 2a4f7482514f1d4e1cffa5d0d23068b6 206 Gene3D G3DSA:3.30.460.10 8 187 5.1E-43 T 23-04-2016 DC74_RS38515 2a4f7482514f1d4e1cffa5d0d23068b6 206 SUPERFAMILY SSF81301 11 186 1.34E-35 T 23-04-2016 DC74_RS38515 2a4f7482514f1d4e1cffa5d0d23068b6 206 PANTHER PTHR34822 9 206 3.8E-28 T 23-04-2016 DC74_RS38515 2a4f7482514f1d4e1cffa5d0d23068b6 206 Pfam PF04229 GrpB protein 9 177 7.9E-39 T 23-04-2016 IPR007344 GrpB/Dephospho-CoA kinase DC74_RS29030 3924795279cd4c0257e114045e153442 388 PANTHER PTHR24421 54 388 7.2E-63 T 23-04-2016 DC74_RS29030 3924795279cd4c0257e114045e153442 388 Pfam PF07730 Histidine kinase 194 263 1.9E-12 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS29030 3924795279cd4c0257e114045e153442 388 SUPERFAMILY SSF55874 265 387 2.34E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29030 3924795279cd4c0257e114045e153442 388 Gene3D G3DSA:3.30.565.10 271 387 1.5E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29030 3924795279cd4c0257e114045e153442 388 PANTHER PTHR24421:SF26 54 388 7.2E-63 T 23-04-2016 DC74_RS29030 3924795279cd4c0257e114045e153442 388 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 301 387 5.3E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 SUPERFAMILY SSF48452 590 659 2.47E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 SUPERFAMILY SSF48452 412 464 2.47E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 Gene3D G3DSA:3.40.50.300 116 213 9.8E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 Gene3D G3DSA:3.40.50.300 9 77 9.8E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 ProSitePatterns PS00622 LuxR-type HTH domain signature. 904 931 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 Pfam PF13191 AAA ATPase domain 14 181 1.5E-26 T 23-04-2016 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 Gene3D G3DSA:1.25.40.10 564 783 1.2E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 PANTHER PTHR16305 14 477 5.9E-31 T 23-04-2016 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 PANTHER PTHR16305 823 864 5.9E-31 T 23-04-2016 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 Gene3D G3DSA:1.10.10.10 883 942 6.4E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 890 904 2.4E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 904 920 2.4E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 920 932 2.4E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 SMART SM00421 887 944 2.7E-17 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 SUPERFAMILY SSF52540 10 89 2.24E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 SUPERFAMILY SSF52540 128 259 2.24E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 Pfam PF00196 Bacterial regulatory proteins, luxR family 889 941 7.8E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 SUPERFAMILY SSF46894 879 944 4.42E-15 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 Gene3D G3DSA:1.25.40.10 816 861 2.4E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS38765 3d24ec1f073305b0002102fc206d5e1a 965 Gene3D G3DSA:1.25.40.10 396 497 2.4E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS13290 11d7c8b126d811c2356ac403dc864df0 453 Gene3D G3DSA:3.30.590.10 108 440 1.4E-111 T 23-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 DC74_RS13290 11d7c8b126d811c2356ac403dc864df0 453 PANTHER PTHR20852:SF7 1 453 2.5E-168 T 23-04-2016 DC74_RS13290 11d7c8b126d811c2356ac403dc864df0 453 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 232 247 - T 23-04-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13290 11d7c8b126d811c2356ac403dc864df0 453 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 98 2.4E-28 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13290 11d7c8b126d811c2356ac403dc864df0 453 Gene3D G3DSA:3.10.20.70 6 107 9.1E-39 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13290 11d7c8b126d811c2356ac403dc864df0 453 SUPERFAMILY SSF54368 8 104 1.96E-30 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13290 11d7c8b126d811c2356ac403dc864df0 453 Pfam PF00120 Glutamine synthetase, catalytic domain 105 448 9.5E-125 T 23-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13290 11d7c8b126d811c2356ac403dc864df0 453 PANTHER PTHR20852 1 453 2.5E-168 T 23-04-2016 DC74_RS13290 11d7c8b126d811c2356ac403dc864df0 453 SUPERFAMILY SSF55931 106 450 9.81E-113 T 23-04-2016 DC74_RS13290 11d7c8b126d811c2356ac403dc864df0 453 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 449 4.0E-131 T 23-04-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13290 11d7c8b126d811c2356ac403dc864df0 453 SMART SM01230 104 363 6.1E-121 T 23-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS25320 d8a5c4e0f480acc9842c90386daad496 142 SMART SM00422 1 69 1.6E-21 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS25320 d8a5c4e0f480acc9842c90386daad496 142 SUPERFAMILY SSF46955 1 123 4.4E-24 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS25320 d8a5c4e0f480acc9842c90386daad496 142 Pfam PF13411 MerR HTH family regulatory protein 1 64 7.7E-18 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS25320 d8a5c4e0f480acc9842c90386daad496 142 PANTHER PTHR30204 1 122 2.7E-19 T 23-04-2016 DC74_RS25320 d8a5c4e0f480acc9842c90386daad496 142 Gene3D G3DSA:1.10.1660.10 1 123 3.7E-31 T 23-04-2016 DC74_RS25320 d8a5c4e0f480acc9842c90386daad496 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.6E-9 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS25320 d8a5c4e0f480acc9842c90386daad496 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.6E-9 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS25320 d8a5c4e0f480acc9842c90386daad496 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.6E-9 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS25320 d8a5c4e0f480acc9842c90386daad496 142 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS30320 9a8fa58e288b39311432f8a6ea2e66a7 102 Pfam PF01527 Transposase 12 85 3.5E-11 T 23-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 DC74_RS30320 9a8fa58e288b39311432f8a6ea2e66a7 102 PANTHER PTHR33215 10 100 5.2E-21 T 23-04-2016 DC74_RS30320 9a8fa58e288b39311432f8a6ea2e66a7 102 SUPERFAMILY SSF46689 11 100 4.12E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS30320 9a8fa58e288b39311432f8a6ea2e66a7 102 Gene3D G3DSA:1.10.10.60 16 95 3.3E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS28125 e38061659e2d49bcabca78178fd25c6e 269 PIRSF PIRSF000386 1 255 1.2E-92 T 23-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 DC74_RS28125 e38061659e2d49bcabca78178fd25c6e 269 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 269 100.048 T 23-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 DC74_RS28125 e38061659e2d49bcabca78178fd25c6e 269 PANTHER PTHR32125:SF1 1 235 1.8E-94 T 23-04-2016 DC74_RS28125 e38061659e2d49bcabca78178fd25c6e 269 PANTHER PTHR32125 1 235 1.8E-94 T 23-04-2016 DC74_RS28125 e38061659e2d49bcabca78178fd25c6e 269 Gene3D G3DSA:3.40.1280.10 1 163 9.5E-64 T 23-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DC74_RS28125 e38061659e2d49bcabca78178fd25c6e 269 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 228 2.1E-68 T 23-04-2016 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 DC74_RS28125 e38061659e2d49bcabca78178fd25c6e 269 Gene3D G3DSA:1.10.1270.20 164 252 1.7E-28 T 23-04-2016 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 DC74_RS28125 e38061659e2d49bcabca78178fd25c6e 269 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 234 5.5E-67 T 23-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 DC74_RS28125 e38061659e2d49bcabca78178fd25c6e 269 SUPERFAMILY SSF75217 1 241 1.57E-84 T 23-04-2016 IPR029028 Alpha/beta knot methyltransferases DC74_RS16460 d4dedbabf073a246f84a6cf78cafaa8e 252 Gene3D G3DSA:1.10.260.40 2 56 1.1E-6 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS16460 d4dedbabf073a246f84a6cf78cafaa8e 252 SUPERFAMILY SSF47413 3 61 6.22E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS03210 cb49886081c97edcf099b08ffa5a4595 385 PANTHER PTHR10909 11 385 6.7E-131 T 23-04-2016 DC74_RS03210 cb49886081c97edcf099b08ffa5a4595 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 385 3.4E-48 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS03210 cb49886081c97edcf099b08ffa5a4595 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 122 5.5E-27 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS03210 cb49886081c97edcf099b08ffa5a4595 385 Gene3D G3DSA:2.40.110.10 130 228 2.0E-33 T 23-04-2016 DC74_RS03210 cb49886081c97edcf099b08ffa5a4595 385 SUPERFAMILY SSF56645 11 248 3.66E-65 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS03210 cb49886081c97edcf099b08ffa5a4595 385 PANTHER PTHR10909:SF305 11 385 6.7E-131 T 23-04-2016 DC74_RS03210 cb49886081c97edcf099b08ffa5a4595 385 Gene3D G3DSA:1.20.140.10 229 385 1.1E-65 T 23-04-2016 DC74_RS03210 cb49886081c97edcf099b08ffa5a4595 385 Gene3D G3DSA:1.10.540.10 11 122 2.3E-29 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS03210 cb49886081c97edcf099b08ffa5a4595 385 SUPERFAMILY SSF47203 236 385 4.35E-55 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS03210 cb49886081c97edcf099b08ffa5a4595 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 224 3.2E-23 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 71 299 1.3E-42 T 23-04-2016 IPR003741 LUD domain DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 Pfam PF11870 Domain of unknown function (DUF3390) 396 474 2.2E-12 T 23-04-2016 IPR024569 4Fe-4S binding protein, C-terminal DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 PANTHER PTHR32479 25 476 7.3E-181 T 23-04-2016 DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 21 460 2.0E-139 T 23-04-2016 IPR004452 4Fe-4S binding protein GO:0019516 DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 Gene3D G3DSA:3.40.50.10420 197 300 9.2E-42 T 23-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 Gene3D G3DSA:3.40.50.10420 66 129 9.2E-42 T 23-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 SUPERFAMILY SSF100950 65 90 1.26E-33 T 23-04-2016 DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 SUPERFAMILY SSF100950 136 300 1.26E-33 T 23-04-2016 DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 Gene3D G3DSA:1.10.1060.10 314 399 1.6E-12 T 23-04-2016 DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 SUPERFAMILY SSF54862 296 401 1.72E-16 T 23-04-2016 DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 Pfam PF13183 4Fe-4S dicluster domain 315 384 2.8E-11 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 PANTHER PTHR32479:SF10 25 476 7.3E-181 T 23-04-2016 DC74_RS38410 ecc0c02e17243d7aa982d2ce62ce5b78 479 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 318 329 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS16490 204668dec38ad61616ba53cfc8a283e6 454 PANTHER PTHR11748 2 454 5.4E-165 T 23-04-2016 DC74_RS16490 204668dec38ad61616ba53cfc8a283e6 454 PANTHER PTHR11748:SF78 2 454 5.4E-165 T 23-04-2016 DC74_RS16490 204668dec38ad61616ba53cfc8a283e6 454 Gene3D G3DSA:3.30.43.10 2 94 7.1E-25 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS16490 204668dec38ad61616ba53cfc8a283e6 454 Gene3D G3DSA:3.30.465.10 95 215 1.2E-44 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS16490 204668dec38ad61616ba53cfc8a283e6 454 SUPERFAMILY SSF56176 2 215 1.31E-69 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS16490 204668dec38ad61616ba53cfc8a283e6 454 Pfam PF01565 FAD binding domain 39 177 2.8E-40 T 23-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DC74_RS16490 204668dec38ad61616ba53cfc8a283e6 454 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 453 2.6E-66 T 23-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 DC74_RS16490 204668dec38ad61616ba53cfc8a283e6 454 Gene3D G3DSA:1.10.45.10 414 453 3.9E-13 T 23-04-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 DC74_RS16490 204668dec38ad61616ba53cfc8a283e6 454 SUPERFAMILY SSF55103 189 453 2.13E-61 T 23-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DC74_RS11100 d61afe36c3ee7297ba2400998e7335e9 585 Gene3D G3DSA:3.40.50.300 457 544 5.6E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11100 d61afe36c3ee7297ba2400998e7335e9 585 SUPERFAMILY SSF52540 6 50 2.23E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11100 d61afe36c3ee7297ba2400998e7335e9 585 SUPERFAMILY SSF52540 342 533 2.23E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11100 d61afe36c3ee7297ba2400998e7335e9 585 Pfam PF02463 RecF/RecN/SMC N terminal domain 15 538 8.9E-17 T 23-04-2016 IPR003395 RecF/RecN/SMC, N-terminal DC74_RS11100 d61afe36c3ee7297ba2400998e7335e9 585 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 579 6.9E-158 T 23-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 DC74_RS11100 d61afe36c3ee7297ba2400998e7335e9 585 SUPERFAMILY SSF52540 1 220 8.6E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11100 d61afe36c3ee7297ba2400998e7335e9 585 PANTHER PTHR11059 2 411 1.2E-150 T 23-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 DC74_RS11100 d61afe36c3ee7297ba2400998e7335e9 585 PANTHER PTHR11059 428 582 1.2E-150 T 23-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 DC74_RS11100 d61afe36c3ee7297ba2400998e7335e9 585 PIRSF PIRSF003128 1 583 2.7E-148 T 23-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 DC74_RS11100 d61afe36c3ee7297ba2400998e7335e9 585 Gene3D G3DSA:3.40.50.300 2 209 4.3E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33830 625a71b97b834df9f66c0b7b161509f6 505 PANTHER PTHR10196 21 499 1.2E-73 T 23-04-2016 DC74_RS33830 625a71b97b834df9f66c0b7b161509f6 505 Gene3D G3DSA:3.30.420.40 261 485 9.9E-17 T 23-04-2016 DC74_RS33830 625a71b97b834df9f66c0b7b161509f6 505 SUPERFAMILY SSF53067 20 261 2.59E-45 T 23-04-2016 DC74_RS33830 625a71b97b834df9f66c0b7b161509f6 505 SUPERFAMILY SSF53067 263 482 6.15E-24 T 23-04-2016 DC74_RS33830 625a71b97b834df9f66c0b7b161509f6 505 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 19 258 1.9E-36 T 23-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 DC74_RS33830 625a71b97b834df9f66c0b7b161509f6 505 Gene3D G3DSA:3.30.420.40 20 259 1.0E-45 T 23-04-2016 DC74_RS33830 625a71b97b834df9f66c0b7b161509f6 505 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 328 444 8.4E-9 T 23-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 DC74_RS33830 625a71b97b834df9f66c0b7b161509f6 505 PIRSF PIRSF000538 17 495 4.3E-63 T 23-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 DC74_RS21935 a5c73c740b9dd8fe712d9e0694e5dff4 199 PANTHER PTHR30446:SF0 1 199 3.8E-117 T 23-04-2016 DC74_RS21935 a5c73c740b9dd8fe712d9e0694e5dff4 199 Pfam PF13662 Toprim domain 80 170 4.4E-26 T 23-04-2016 IPR006171 Toprim domain DC74_RS21935 a5c73c740b9dd8fe712d9e0694e5dff4 199 Gene3D G3DSA:3.40.50.140 114 169 3.2E-6 T 23-04-2016 IPR006171 Toprim domain DC74_RS21935 a5c73c740b9dd8fe712d9e0694e5dff4 199 SMART SM00493 79 164 3.2E-17 T 23-04-2016 IPR006171 Toprim domain DC74_RS21935 a5c73c740b9dd8fe712d9e0694e5dff4 199 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 23-04-2016 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 DC74_RS21935 a5c73c740b9dd8fe712d9e0694e5dff4 199 Pfam PF00633 Helix-hairpin-helix motif 2 27 4.7E-6 T 23-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 DC74_RS21935 a5c73c740b9dd8fe712d9e0694e5dff4 199 Gene3D G3DSA:3.90.79.10 50 113 4.0E-4 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS21935 a5c73c740b9dd8fe712d9e0694e5dff4 199 PANTHER PTHR30446 1 199 3.8E-117 T 23-04-2016 DC74_RS21935 a5c73c740b9dd8fe712d9e0694e5dff4 199 SUPERFAMILY SSF111304 3 197 1.16E-74 T 23-04-2016 IPR023627 Recombination protein RecR DC74_RS21935 a5c73c740b9dd8fe712d9e0694e5dff4 199 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 1.1E-83 T 23-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 DC74_RS21935 a5c73c740b9dd8fe712d9e0694e5dff4 199 Pfam PF02132 RecR protein 38 77 5.2E-16 T 23-04-2016 IPR023628 Recombination protein RecR, C4-type zinc finger DC74_RS21935 a5c73c740b9dd8fe712d9e0694e5dff4 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 108.544 T 23-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 DC74_RS32570 43d9d5af42cb1cc7da3a0bc256cc8702 678 Gene3D G3DSA:3.40.50.980 2 111 5.3E-23 T 23-04-2016 DC74_RS32570 43d9d5af42cb1cc7da3a0bc256cc8702 678 SUPERFAMILY SSF52777 419 674 8.67E-19 T 23-04-2016 DC74_RS32570 43d9d5af42cb1cc7da3a0bc256cc8702 678 Pfam PF00550 Phosphopantetheine attachment site 153 202 4.9E-6 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS32570 43d9d5af42cb1cc7da3a0bc256cc8702 678 SUPERFAMILY SSF56801 2 155 1.83E-28 T 23-04-2016 DC74_RS32570 43d9d5af42cb1cc7da3a0bc256cc8702 678 Pfam PF00501 AMP-binding enzyme 2 115 2.9E-12 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS32570 43d9d5af42cb1cc7da3a0bc256cc8702 678 Pfam PF00668 Condensation domain 230 529 1.4E-27 T 23-04-2016 IPR001242 Condensation domain DC74_RS32570 43d9d5af42cb1cc7da3a0bc256cc8702 678 SUPERFAMILY SSF47336 153 237 2.45E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS32570 43d9d5af42cb1cc7da3a0bc256cc8702 678 PANTHER PTHR24095 1 425 4.2E-27 T 23-04-2016 DC74_RS32570 43d9d5af42cb1cc7da3a0bc256cc8702 678 Gene3D G3DSA:1.10.1200.10 153 208 1.1E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS32570 43d9d5af42cb1cc7da3a0bc256cc8702 678 SUPERFAMILY SSF52777 229 403 1.22E-28 T 23-04-2016 DC74_RS32570 43d9d5af42cb1cc7da3a0bc256cc8702 678 PANTHER PTHR24095:SF137 1 425 4.2E-27 T 23-04-2016 DC74_RS07205 cc3ce9fea379765e300ce81ec61705e5 168 SUPERFAMILY SSF109854 4 163 3.97E-42 T 23-04-2016 DC74_RS07205 cc3ce9fea379765e300ce81ec61705e5 168 Gene3D G3DSA:1.20.120.450 3 167 8.2E-46 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS07205 cc3ce9fea379765e300ce81ec61705e5 168 Pfam PF04978 Protein of unknown function (DUF664) 17 164 4.0E-46 T 23-04-2016 IPR007061 Protein of unknown function DUF664 DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 Pfam PF00106 short chain dehydrogenase 3 190 1.5E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 Gene3D G3DSA:3.40.50.720 2 248 2.0E-66 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 SUPERFAMILY SSF51735 2 246 7.52E-62 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 PANTHER PTHR24322 148 180 1.1E-49 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 PANTHER PTHR24322 7 132 1.1E-49 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 5.6E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 5.6E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 5.6E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.6E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 5.6E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 3.2E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 3.2E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 3.2E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04260 729d78a78c21f8f501f060736fbad7b0 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS02755 effcceabdd26323055d5704216f94984 312 PANTHER PTHR32322 1 308 2.8E-55 T 23-04-2016 DC74_RS02755 effcceabdd26323055d5704216f94984 312 Pfam PF00892 EamA-like transporter family 150 285 1.4E-12 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS02755 effcceabdd26323055d5704216f94984 312 Pfam PF00892 EamA-like transporter family 4 134 4.5E-15 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS02755 effcceabdd26323055d5704216f94984 312 PANTHER PTHR32322:SF8 1 308 2.8E-55 T 23-04-2016 DC74_RS02755 effcceabdd26323055d5704216f94984 312 SUPERFAMILY SSF103481 35 138 1.57E-15 T 23-04-2016 DC74_RS02755 effcceabdd26323055d5704216f94984 312 SUPERFAMILY SSF103481 186 287 2.09E-8 T 23-04-2016 DC74_RS11780 57be5c31a2d90d9ff5fdb8f228e32c9d 372 PIRSF PIRSF036915 1 372 4.1E-178 T 23-04-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 DC74_RS11780 57be5c31a2d90d9ff5fdb8f228e32c9d 372 Pfam PF00923 Transaldolase 15 359 5.7E-80 T 23-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 DC74_RS11780 57be5c31a2d90d9ff5fdb8f228e32c9d 372 PANTHER PTHR10683 1 364 6.5E-247 T 23-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 DC74_RS11780 57be5c31a2d90d9ff5fdb8f228e32c9d 372 ProSitePatterns PS01054 Transaldolase signature 1. 41 49 - T 23-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 DC74_RS11780 57be5c31a2d90d9ff5fdb8f228e32c9d 372 TIGRFAM TIGR00876 tal_mycobact: transaldolase 12 359 4.3E-133 T 23-04-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 DC74_RS11780 57be5c31a2d90d9ff5fdb8f228e32c9d 372 Hamap MF_00493 Transaldolase [tal]. 1 370 162.463 T 23-04-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 DC74_RS11780 57be5c31a2d90d9ff5fdb8f228e32c9d 372 PANTHER PTHR10683:SF12 1 364 6.5E-247 T 23-04-2016 DC74_RS11780 57be5c31a2d90d9ff5fdb8f228e32c9d 372 Gene3D G3DSA:3.20.20.70 1 359 2.3E-122 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS11780 57be5c31a2d90d9ff5fdb8f228e32c9d 372 SUPERFAMILY SSF51569 2 359 1.03E-74 T 23-04-2016 DC74_RS13805 8a05acb3f10dcd4093767bd96fe7e914 214 PANTHER PTHR24094 33 214 5.1E-75 T 23-04-2016 DC74_RS13805 8a05acb3f10dcd4093767bd96fe7e914 214 PANTHER PTHR24094:SF14 33 214 5.1E-75 T 23-04-2016 DC74_RS13805 8a05acb3f10dcd4093767bd96fe7e914 214 Pfam PF07510 Protein of unknown function (DUF1524) 111 209 3.0E-10 T 23-04-2016 IPR011089 Domain of unknown function DUF1524 DC74_RS16855 14575b11763f7a944b21268c034085ee 231 Gene3D G3DSA:3.30.160.100 2 102 1.0E-25 T 23-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 DC74_RS16855 14575b11763f7a944b21268c034085ee 231 SUPERFAMILY SSF69754 3 108 4.84E-22 T 23-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 DC74_RS16855 14575b11763f7a944b21268c034085ee 231 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 2 104 1.9E-21 T 23-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 DC74_RS16855 14575b11763f7a944b21268c034085ee 231 PANTHER PTHR33231:SF1 1 215 2.1E-53 T 23-04-2016 DC74_RS16855 14575b11763f7a944b21268c034085ee 231 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 100 4.6E-19 T 23-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 DC74_RS16855 14575b11763f7a944b21268c034085ee 231 PANTHER PTHR33231 1 215 2.1E-53 T 23-04-2016 DC74_RS16855 14575b11763f7a944b21268c034085ee 231 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 155 209 5.2E-22 T 23-04-2016 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal DC74_RS25235 f4c56ab43fd0bc83987c957598856d21 399 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 41 54 - T 23-04-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 DC74_RS25235 f4c56ab43fd0bc83987c957598856d21 399 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 20 397 1.6E-131 T 23-04-2016 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00052 DC74_RS25235 f4c56ab43fd0bc83987c957598856d21 399 Gene3D G3DSA:3.40.50.1100 69 317 1.2E-74 T 23-04-2016 DC74_RS25235 f4c56ab43fd0bc83987c957598856d21 399 Gene3D G3DSA:3.30.70.260 324 390 6.6E-4 T 23-04-2016 DC74_RS25235 f4c56ab43fd0bc83987c957598856d21 399 PANTHER PTHR10314 1 353 6.6E-150 T 23-04-2016 DC74_RS25235 f4c56ab43fd0bc83987c957598856d21 399 SUPERFAMILY SSF53686 3 309 3.67E-92 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS25235 f4c56ab43fd0bc83987c957598856d21 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 15 301 4.0E-80 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS25235 f4c56ab43fd0bc83987c957598856d21 399 PANTHER PTHR10314:SF17 1 353 6.6E-150 T 23-04-2016 DC74_RS22900 7b225243bc80ea1061e32b034a1d41fc 334 Gene3D G3DSA:3.90.1720.10 192 321 1.2E-37 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS22900 7b225243bc80ea1061e32b034a1d41fc 334 Gene3D G3DSA:1.10.530.10 48 191 5.3E-32 T 23-04-2016 DC74_RS22900 7b225243bc80ea1061e32b034a1d41fc 334 SUPERFAMILY SSF53955 47 186 2.09E-32 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS22900 7b225243bc80ea1061e32b034a1d41fc 334 Pfam PF01464 Transglycosylase SLT domain 64 174 2.1E-15 T 23-04-2016 IPR008258 Transglycosylase SLT domain 1 DC74_RS22900 7b225243bc80ea1061e32b034a1d41fc 334 PANTHER PTHR21666 143 322 6.0E-31 T 23-04-2016 DC74_RS22900 7b225243bc80ea1061e32b034a1d41fc 334 SUPERFAMILY SSF54001 192 320 1.72E-35 T 23-04-2016 DC74_RS22900 7b225243bc80ea1061e32b034a1d41fc 334 PANTHER PTHR21666:SF190 143 322 6.0E-31 T 23-04-2016 DC74_RS22900 7b225243bc80ea1061e32b034a1d41fc 334 Pfam PF00877 NlpC/P60 family 211 307 4.0E-23 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 Gene3D G3DSA:2.70.150.10 91 239 5.8E-25 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 Pfam PF00122 E1-E2 ATPase 110 330 6.2E-54 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 SUPERFAMILY SSF56784 398 639 1.27E-48 T 23-04-2016 IPR023214 HAD-like domain DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 SUPERFAMILY SSF56784 338 357 1.27E-48 T 23-04-2016 IPR023214 HAD-like domain DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 Pfam PF00702 haloacid dehalogenase-like hydrolase 335 552 1.7E-38 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 ProSitePatterns PS01229 Hypothetical cof family signature 2. 539 561 - T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 112 603 6.1E-68 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 341 347 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 88 642 4.4E-170 T 23-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 558 5.5E-23 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 563 575 5.5E-23 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 189 203 5.5E-23 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 463 474 5.5E-23 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 486 496 5.5E-23 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 339 353 5.5E-23 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 SUPERFAMILY SSF81653 144 239 6.8E-23 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 PANTHER PTHR24093 53 603 1.7E-211 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 PANTHER PTHR24093:SF317 53 603 1.7E-211 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 Gene3D G3DSA:3.40.50.1000 315 353 2.1E-39 T 23-04-2016 IPR023214 HAD-like domain DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 Gene3D G3DSA:3.40.50.1000 466 604 2.1E-39 T 23-04-2016 IPR023214 HAD-like domain DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 88 644 4.6E-145 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 SUPERFAMILY SSF81665 240 333 6.93E-9 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 SUPERFAMILY SSF81665 90 142 6.93E-9 T 23-04-2016 DC74_RS06675 f9ce7404de3a856d6be372435f5e3a97 656 Gene3D G3DSA:3.40.1110.10 354 465 4.7E-21 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 Pfam PF04542 Sigma-70 region 2 101 170 3.4E-21 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 SUPERFAMILY SSF88659 174 248 1.0E-16 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 Gene3D G3DSA:1.10.10.10 258 317 9.1E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 SUPERFAMILY SSF88659 237 317 1.42E-16 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 PRINTS PR00046 Major sigma-70 factor signature 270 282 8.1E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 PRINTS PR00046 Major sigma-70 factor signature 302 313 8.1E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 PRINTS PR00046 Major sigma-70 factor signature 149 157 8.1E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 PRINTS PR00046 Major sigma-70 factor signature 125 138 8.1E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 PRINTS PR00046 Major sigma-70 factor signature 287 302 8.1E-10 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 Gene3D G3DSA:1.10.601.10 27 43 7.8E-28 T 23-04-2016 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 Gene3D G3DSA:1.10.601.10 93 168 7.8E-28 T 23-04-2016 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 PANTHER PTHR30385 33 321 2.2E-110 T 23-04-2016 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 SUPERFAMILY SSF88946 78 170 3.4E-32 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 PANTHER PTHR30385:SF4 33 321 2.2E-110 T 23-04-2016 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 Gene3D G3DSA:1.10.10.10 169 224 4.1E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 Pfam PF04539 Sigma-70 region 3 184 240 2.0E-16 T 23-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 95 317 3.8E-96 T 23-04-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 97 317 9.5E-38 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26490 7db13cb84bb6a9debc0b5d805a76dc10 321 Pfam PF04545 Sigma-70, region 4 266 315 2.3E-16 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS40605 e35b958f5881d3f3a2e212bf22ef24d4 228 PANTHER PTHR14136:SF12 54 183 3.9E-17 T 23-04-2016 DC74_RS40605 e35b958f5881d3f3a2e212bf22ef24d4 228 SUPERFAMILY SSF141571 41 213 1.28E-30 T 23-04-2016 DC74_RS40605 e35b958f5881d3f3a2e212bf22ef24d4 228 Pfam PF13599 Pentapeptide repeats (9 copies) 41 109 1.4E-7 T 23-04-2016 IPR001646 Pentapeptide repeat DC74_RS40605 e35b958f5881d3f3a2e212bf22ef24d4 228 Pfam PF13599 Pentapeptide repeats (9 copies) 115 183 2.5E-10 T 23-04-2016 IPR001646 Pentapeptide repeat DC74_RS40605 e35b958f5881d3f3a2e212bf22ef24d4 228 PANTHER PTHR14136 54 183 3.9E-17 T 23-04-2016 DC74_RS20410 f87522883433dc57a38cb724ff504f8f 303 SUPERFAMILY SSF53448 7 192 3.03E-25 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS20410 f87522883433dc57a38cb724ff504f8f 303 Pfam PF12804 MobA-like NTP transferase domain 9 155 9.3E-29 T 23-04-2016 IPR025877 MobA-like NTP transferase DC74_RS20410 f87522883433dc57a38cb724ff504f8f 303 Gene3D G3DSA:3.90.550.10 5 200 1.6E-38 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS25670 b8dd2c932237bd1cdeeaf6f118e4598c 115 Pfam PF00589 Phage integrase family 17 85 8.6E-13 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS25670 b8dd2c932237bd1cdeeaf6f118e4598c 115 PANTHER PTHR30349 2 88 4.6E-13 T 23-04-2016 DC74_RS25670 b8dd2c932237bd1cdeeaf6f118e4598c 115 SUPERFAMILY SSF56349 4 88 1.35E-19 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DC74_RS25670 b8dd2c932237bd1cdeeaf6f118e4598c 115 Gene3D G3DSA:1.10.443.10 4 87 3.9E-18 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS19545 4c3b3ab462e58624c5d2a22d590be9e1 249 Gene3D G3DSA:1.10.357.10 26 247 3.3E-61 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS19545 4c3b3ab462e58624c5d2a22d590be9e1 249 PANTHER PTHR30055 23 114 1.5E-30 T 23-04-2016 DC74_RS19545 4c3b3ab462e58624c5d2a22d590be9e1 249 SUPERFAMILY SSF48498 174 245 2.28E-11 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS19545 4c3b3ab462e58624c5d2a22d590be9e1 249 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 82 4.8E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS19545 4c3b3ab462e58624c5d2a22d590be9e1 249 SUPERFAMILY SSF46689 26 108 4.49E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS19545 4c3b3ab462e58624c5d2a22d590be9e1 249 PANTHER PTHR30055:SF43 23 114 1.5E-30 T 23-04-2016 DC74_RS19545 4c3b3ab462e58624c5d2a22d590be9e1 249 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 58 81 8.4E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS19545 4c3b3ab462e58624c5d2a22d590be9e1 249 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 51 8.4E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS36395 d3e0e4094640c33668c25650d9015dbe 300 Gene3D G3DSA:3.30.360.10 142 274 4.2E-66 T 23-04-2016 DC74_RS36395 d3e0e4094640c33668c25650d9015dbe 300 PIRSF PIRSF015689 3 300 5.0E-133 T 23-04-2016 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 DC74_RS36395 d3e0e4094640c33668c25650d9015dbe 300 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 300 137.178 T 23-04-2016 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 DC74_RS36395 d3e0e4094640c33668c25650d9015dbe 300 SUPERFAMILY SSF51735 7 153 1.57E-25 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36395 d3e0e4094640c33668c25650d9015dbe 300 SMART SM00859 8 121 1.0E-5 T 23-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DC74_RS36395 d3e0e4094640c33668c25650d9015dbe 300 Gene3D G3DSA:3.40.50.720 5 141 2.0E-68 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36395 d3e0e4094640c33668c25650d9015dbe 300 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 116 2.8E-10 T 23-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DC74_RS36395 d3e0e4094640c33668c25650d9015dbe 300 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 6 298 2.1E-134 T 23-04-2016 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 DC74_RS36395 d3e0e4094640c33668c25650d9015dbe 300 SUPERFAMILY SSF55347 129 274 7.85E-59 T 23-04-2016 DC74_RS36395 d3e0e4094640c33668c25650d9015dbe 300 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 129 274 1.9E-63 T 23-04-2016 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 DC74_RS36395 d3e0e4094640c33668c25650d9015dbe 300 PANTHER PTHR41706 2 300 1.5E-137 T 23-04-2016 DC74_RS10920 49dca51c1c06b1aaf47b4d52ef0ce3b0 200 SUPERFAMILY SSF52540 12 187 6.26E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10920 49dca51c1c06b1aaf47b4d52ef0ce3b0 200 PANTHER PTHR11711:SF117 13 183 1.8E-53 T 23-04-2016 DC74_RS10920 49dca51c1c06b1aaf47b4d52ef0ce3b0 200 Pfam PF03029 Conserved hypothetical ATP binding protein 17 180 9.2E-23 T 23-04-2016 IPR004130 GPN-loop GTPase DC74_RS10920 49dca51c1c06b1aaf47b4d52ef0ce3b0 200 Gene3D G3DSA:3.40.50.300 12 186 3.3E-15 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10920 49dca51c1c06b1aaf47b4d52ef0ce3b0 200 PANTHER PTHR11711 13 183 1.8E-53 T 23-04-2016 DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 PANTHER PTHR24322 13 139 5.1E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 PANTHER PTHR24322 155 187 5.1E-34 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 SUPERFAMILY SSF51735 4 259 4.87E-54 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 Gene3D G3DSA:3.40.50.720 4 206 1.5E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 186 0.0013 T 23-04-2016 DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.3E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.3E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.3E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.3E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.3E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.5E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.5E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.5E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04540 6c904939bb10ff6d05fed9f59485b81f 296 Pfam PF00106 short chain dehydrogenase 10 197 1.5E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS21800 67b9fc80ad944ce328cd847a606ac9f3 281 PANTHER PTHR12737:SF20 8 280 1.7E-107 T 23-04-2016 DC74_RS21800 67b9fc80ad944ce328cd847a606ac9f3 281 PANTHER PTHR12737 8 280 1.7E-107 T 23-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS21800 67b9fc80ad944ce328cd847a606ac9f3 281 Gene3D G3DSA:3.75.10.10 6 279 1.0E-62 T 23-04-2016 DC74_RS21800 67b9fc80ad944ce328cd847a606ac9f3 281 Pfam PF02274 Amidinotransferase 12 279 5.1E-18 T 23-04-2016 DC74_RS21800 67b9fc80ad944ce328cd847a606ac9f3 281 SUPERFAMILY SSF55909 4 280 1.12E-57 T 23-04-2016 DC74_RS01675 34ccaa899fe90ad603f0b31b0d7ae936 367 PANTHER PTHR11695 138 360 3.6E-131 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS01675 34ccaa899fe90ad603f0b31b0d7ae936 367 Gene3D G3DSA:3.40.50.720 191 297 6.4E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01675 34ccaa899fe90ad603f0b31b0d7ae936 367 Pfam PF00107 Zinc-binding dehydrogenase 198 289 2.3E-18 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS01675 34ccaa899fe90ad603f0b31b0d7ae936 367 SUPERFAMILY SSF51735 160 327 4.66E-32 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01675 34ccaa899fe90ad603f0b31b0d7ae936 367 SUPERFAMILY SSF50129 2 194 5.33E-49 T 23-04-2016 IPR011032 GroES-like DC74_RS01675 34ccaa899fe90ad603f0b31b0d7ae936 367 PANTHER PTHR11695:SF571 138 360 3.6E-131 T 23-04-2016 DC74_RS01675 34ccaa899fe90ad603f0b31b0d7ae936 367 PANTHER PTHR11695:SF571 15 107 3.6E-131 T 23-04-2016 DC74_RS01675 34ccaa899fe90ad603f0b31b0d7ae936 367 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 155 1.6E-20 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS01675 34ccaa899fe90ad603f0b31b0d7ae936 367 SMART SM00829 9 360 0.0015 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS01675 34ccaa899fe90ad603f0b31b0d7ae936 367 PANTHER PTHR11695 15 107 3.6E-131 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS01675 34ccaa899fe90ad603f0b31b0d7ae936 367 Gene3D G3DSA:3.90.180.10 3 190 1.8E-48 T 23-04-2016 IPR011032 GroES-like DC74_RS18040 93f11c19897a84220a710d54857db30d 249 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 54 7.4E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS18040 93f11c19897a84220a710d54857db30d 249 PANTHER PTHR30055:SF39 3 239 9.9E-64 T 23-04-2016 DC74_RS18040 93f11c19897a84220a710d54857db30d 249 Gene3D G3DSA:1.10.357.10 4 187 7.1E-30 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS18040 93f11c19897a84220a710d54857db30d 249 PANTHER PTHR30055 3 239 9.9E-64 T 23-04-2016 DC74_RS18040 93f11c19897a84220a710d54857db30d 249 SUPERFAMILY SSF46689 4 78 1.12E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS15760 8d1f65a80d924b171504feda15c23222 95 PRINTS PR00944 Copper ion binding protein signature 78 91 2.0E-5 T 23-04-2016 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 DC74_RS15760 8d1f65a80d924b171504feda15c23222 95 PRINTS PR00944 Copper ion binding protein signature 28 40 2.0E-5 T 23-04-2016 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 DC74_RS15760 8d1f65a80d924b171504feda15c23222 95 PRINTS PR00944 Copper ion binding protein signature 40 53 2.0E-5 T 23-04-2016 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 DC74_RS15760 8d1f65a80d924b171504feda15c23222 95 SUPERFAMILY SSF55008 26 92 8.25E-15 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 DC74_RS15760 8d1f65a80d924b171504feda15c23222 95 Gene3D G3DSA:3.30.70.100 28 91 8.6E-19 T 23-04-2016 DC74_RS15760 8d1f65a80d924b171504feda15c23222 95 Pfam PF00403 Heavy-metal-associated domain 30 90 4.2E-13 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 DC74_RS15945 a4fa5414c98a3b429ac092885d9cafad 422 Pfam PF01965 DJ-1/PfpI family 57 191 9.8E-15 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS15945 a4fa5414c98a3b429ac092885d9cafad 422 SUPERFAMILY SSF52317 24 212 3.99E-47 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS15945 a4fa5414c98a3b429ac092885d9cafad 422 Gene3D G3DSA:3.40.50.880 24 212 8.3E-49 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS15945 a4fa5414c98a3b429ac092885d9cafad 422 SUPERFAMILY SSF46689 235 283 3.84E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS15945 a4fa5414c98a3b429ac092885d9cafad 422 Gene3D G3DSA:1.10.10.60 234 286 2.0E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS15945 a4fa5414c98a3b429ac092885d9cafad 422 SUPERFAMILY SSF46689 287 337 6.66E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS15945 a4fa5414c98a3b429ac092885d9cafad 422 PANTHER PTHR11019 18 341 3.4E-156 T 23-04-2016 DC74_RS15945 a4fa5414c98a3b429ac092885d9cafad 422 Pfam PF12833 Helix-turn-helix domain 256 334 7.4E-19 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS15945 a4fa5414c98a3b429ac092885d9cafad 422 PANTHER PTHR11019:SF68 18 341 3.4E-156 T 23-04-2016 DC74_RS15945 a4fa5414c98a3b429ac092885d9cafad 422 Gene3D G3DSA:1.10.10.60 287 336 2.4E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS15945 a4fa5414c98a3b429ac092885d9cafad 422 SMART SM00342 250 333 1.3E-21 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS22080 95925b7c185e54294ef4b0da93ac654b 464 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 28 394 8.6E-96 T 23-04-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 DC74_RS22080 95925b7c185e54294ef4b0da93ac654b 464 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 23 403 20.802 T 23-04-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 DC74_RS22080 95925b7c185e54294ef4b0da93ac654b 464 PANTHER PTHR30341:SF0 6 411 2.6E-177 T 23-04-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 DC74_RS22080 95925b7c185e54294ef4b0da93ac654b 464 PANTHER PTHR30341 6 411 2.6E-177 T 23-04-2016 DC74_RS22080 95925b7c185e54294ef4b0da93ac654b 464 Pfam PF06965 Na+/H+ antiporter 1 26 397 5.8E-132 T 23-04-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 DC74_RS22080 95925b7c185e54294ef4b0da93ac654b 464 Gene3D G3DSA:1.20.1530.10 23 403 2.1E-135 T 23-04-2016 IPR023171 Na/H antiporter domain DC74_RS10905 6d826b204df396588ba3b54ac5ff14dd 287 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 71 174 1.6E-20 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 DC74_RS10905 6d826b204df396588ba3b54ac5ff14dd 287 Gene3D G3DSA:1.10.3720.10 69 279 9.5E-44 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS10905 6d826b204df396588ba3b54ac5ff14dd 287 PANTHER PTHR30450:SF2 54 287 4.7E-84 T 23-04-2016 DC74_RS10905 6d826b204df396588ba3b54ac5ff14dd 287 PANTHER PTHR30450 54 287 4.7E-84 T 23-04-2016 DC74_RS10905 6d826b204df396588ba3b54ac5ff14dd 287 SUPERFAMILY SSF161098 71 265 1.07E-41 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS10905 6d826b204df396588ba3b54ac5ff14dd 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 278 3.4E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS17600 fe0eaa5025a38d37141e4400ad51ecbd 196 SUPERFAMILY SSF52980 33 157 8.04E-11 T 23-04-2016 IPR011335 Restriction endonuclease type II-like DC74_RS17600 fe0eaa5025a38d37141e4400ad51ecbd 196 Pfam PF05685 Putative restriction endonuclease 33 159 6.4E-13 T 23-04-2016 IPR008538 Domain of unknown function DUF820 DC74_RS17600 fe0eaa5025a38d37141e4400ad51ecbd 196 Gene3D G3DSA:3.90.1570.10 33 157 2.1E-10 T 23-04-2016 IPR012296 Nuclease, putative, TT1808 DC74_RS01710 391b3ce1aabd7da69bcce2c2393cd0df 162 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS01710 391b3ce1aabd7da69bcce2c2393cd0df 162 Pfam PF00293 NUDIX domain 5 127 3.3E-13 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS01710 391b3ce1aabd7da69bcce2c2393cd0df 162 Gene3D G3DSA:3.90.79.10 4 130 5.5E-21 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS01710 391b3ce1aabd7da69bcce2c2393cd0df 162 SUPERFAMILY SSF55811 4 131 6.5E-19 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS11990 f3964b7245950611fed802b184829f35 727 PRINTS PR00364 Disease resistance protein signature 76 91 2.5E-8 T 23-04-2016 DC74_RS11990 f3964b7245950611fed802b184829f35 727 PRINTS PR00364 Disease resistance protein signature 242 256 2.5E-8 T 23-04-2016 DC74_RS11990 f3964b7245950611fed802b184829f35 727 PRINTS PR00364 Disease resistance protein signature 154 168 2.5E-8 T 23-04-2016 DC74_RS11990 f3964b7245950611fed802b184829f35 727 SUPERFAMILY SSF48452 553 688 1.44E-11 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS11990 f3964b7245950611fed802b184829f35 727 Pfam PF00931 NB-ARC domain 77 257 3.2E-8 T 23-04-2016 IPR002182 NB-ARC GO:0043531 DC74_RS11990 f3964b7245950611fed802b184829f35 727 Gene3D G3DSA:3.40.50.300 70 191 3.7E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11990 f3964b7245950611fed802b184829f35 727 PANTHER PTHR22845:SF4 33 688 6.9E-34 T 23-04-2016 DC74_RS11990 f3964b7245950611fed802b184829f35 727 Gene3D G3DSA:1.25.40.10 547 713 3.1E-14 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS11990 f3964b7245950611fed802b184829f35 727 SUPERFAMILY SSF52540 42 263 6.55E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11990 f3964b7245950611fed802b184829f35 727 PANTHER PTHR22845 33 688 6.9E-34 T 23-04-2016 DC74_RS36670 63d9fed3e34b9f4a5bb786cd64d1c22e 117 SUPERFAMILY SSF46785 10 96 3.83E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36670 63d9fed3e34b9f4a5bb786cd64d1c22e 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 1.3E-9 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS36670 63d9fed3e34b9f4a5bb786cd64d1c22e 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 22 37 1.3E-9 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS36670 63d9fed3e34b9f4a5bb786cd64d1c22e 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.3E-9 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS36670 63d9fed3e34b9f4a5bb786cd64d1c22e 117 PANTHER PTHR33154 8 109 7.9E-22 T 23-04-2016 DC74_RS36670 63d9fed3e34b9f4a5bb786cd64d1c22e 117 SMART SM00418 20 98 3.7E-17 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS36670 63d9fed3e34b9f4a5bb786cd64d1c22e 117 Pfam PF01022 Bacterial regulatory protein, arsR family 28 73 1.6E-9 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS36670 63d9fed3e34b9f4a5bb786cd64d1c22e 117 Gene3D G3DSA:1.10.10.10 6 96 7.2E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 SUPERFAMILY SSF54909 66 144 2.28E-7 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 Pfam PF13404 AsnC-type helix-turn-helix domain 6 47 2.8E-14 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 Pfam PF13404 AsnC-type helix-turn-helix domain 156 196 1.2E-13 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 SMART SM00344 6 110 7.0E-11 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 SMART SM00344 156 259 1.3E-5 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 PANTHER PTHR30154 1 163 4.9E-29 T 23-04-2016 DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 156 172 3.2E-11 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 183 202 3.2E-11 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 172 183 3.2E-11 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 SUPERFAMILY SSF46785 156 203 1.43E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 Gene3D G3DSA:1.10.10.10 154 203 1.6E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 Gene3D G3DSA:1.10.10.10 5 53 2.9E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 SUPERFAMILY SSF46785 6 53 4.63E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 Pfam PF01037 Lrp/AsnC ligand binding domain 82 135 2.6E-6 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS14770 5098020c47ee3c0e9de2e2d88bb06f12 299 Gene3D G3DSA:3.30.70.920 59 135 6.9E-8 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS03530 56681e4af5eef236fa62595d9d4e3fe8 658 PANTHER PTHR31263 66 424 2.3E-39 T 23-04-2016 DC74_RS03530 56681e4af5eef236fa62595d9d4e3fe8 658 SUPERFAMILY SSF51445 65 440 1.37E-42 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS03530 56681e4af5eef236fa62595d9d4e3fe8 658 Gene3D G3DSA:3.20.20.80 62 436 8.6E-65 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS03530 56681e4af5eef236fa62595d9d4e3fe8 658 PANTHER PTHR31263:SF0 66 424 2.3E-39 T 23-04-2016 DC74_RS03530 56681e4af5eef236fa62595d9d4e3fe8 658 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 126 420 1.2E-29 T 23-04-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 DC74_RS17410 96c46f088e8394db2d0d968fb3ce3832 314 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 135 209 4.0E-25 T 23-04-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core DC74_RS17410 96c46f088e8394db2d0d968fb3ce3832 314 PANTHER PTHR30522:SF0 1 310 9.4E-77 T 23-04-2016 IPR011551 NTP pyrophosphohydrolase MazG DC74_RS17410 96c46f088e8394db2d0d968fb3ce3832 314 SUPERFAMILY SSF101386 116 214 9.0E-23 T 23-04-2016 DC74_RS17410 96c46f088e8394db2d0d968fb3ce3832 314 PANTHER PTHR30522 1 310 9.4E-77 T 23-04-2016 DC74_RS17410 96c46f088e8394db2d0d968fb3ce3832 314 Gene3D G3DSA:1.10.287.1080 115 186 1.8E-12 T 23-04-2016 DC74_RS21500 5f9005f287455f0497ec3f9f5c4bb2d0 465 Pfam PF04138 GtrA-like protein 295 412 2.3E-12 T 23-04-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 DC74_RS21500 5f9005f287455f0497ec3f9f5c4bb2d0 465 Pfam PF00535 Glycosyl transferase family 2 30 193 1.1E-19 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS21500 5f9005f287455f0497ec3f9f5c4bb2d0 465 SUPERFAMILY SSF53448 28 239 4.69E-32 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS21500 5f9005f287455f0497ec3f9f5c4bb2d0 465 Gene3D G3DSA:3.90.550.10 30 224 1.5E-17 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS21500 5f9005f287455f0497ec3f9f5c4bb2d0 465 PANTHER PTHR10859 13 254 8.5E-49 T 23-04-2016 DC74_RS29165 57fe0118cd7b89a41cd7e6d2f4a61da8 197 PANTHER PTHR12418 63 173 1.4E-16 T 23-04-2016 DC74_RS29165 57fe0118cd7b89a41cd7e6d2f4a61da8 197 Gene3D G3DSA:3.10.129.10 24 170 5.2E-42 T 23-04-2016 IPR029069 HotDog domain DC74_RS29165 57fe0118cd7b89a41cd7e6d2f4a61da8 197 Pfam PF03061 Thioesterase superfamily 78 138 3.1E-8 T 23-04-2016 IPR006683 Thioesterase domain DC74_RS29165 57fe0118cd7b89a41cd7e6d2f4a61da8 197 SUPERFAMILY SSF54637 23 162 1.33E-31 T 23-04-2016 IPR029069 HotDog domain DC74_RS24010 a2a7db464aec6a66f358887b4004e1ed 405 SUPERFAMILY SSF48452 151 228 8.01E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS24010 a2a7db464aec6a66f358887b4004e1ed 405 SMART SM00530 13 69 1.0E-9 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS24010 a2a7db464aec6a66f358887b4004e1ed 405 Gene3D G3DSA:1.25.40.10 163 290 4.7E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS24010 a2a7db464aec6a66f358887b4004e1ed 405 Gene3D G3DSA:1.10.260.40 8 70 2.1E-17 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS24010 a2a7db464aec6a66f358887b4004e1ed 405 SUPERFAMILY SSF47413 9 71 1.23E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS24010 a2a7db464aec6a66f358887b4004e1ed 405 Pfam PF13560 Helix-turn-helix domain 10 65 6.1E-11 T 23-04-2016 DC74_RS25480 22e4a189ec4c28a2e537e894c7b0baf8 259 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 30 259 36.37 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 DC74_RS25480 22e4a189ec4c28a2e537e894c7b0baf8 259 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 204 221 - T 23-04-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 DC74_RS25480 22e4a189ec4c28a2e537e894c7b0baf8 259 PANTHER PTHR10291:SF1 6 258 9.4E-115 T 23-04-2016 DC74_RS25480 22e4a189ec4c28a2e537e894c7b0baf8 259 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 30 258 2.4E-65 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 DC74_RS25480 22e4a189ec4c28a2e537e894c7b0baf8 259 Gene3D G3DSA:3.40.1180.10 16 258 5.7E-88 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 DC74_RS25480 22e4a189ec4c28a2e537e894c7b0baf8 259 PANTHER PTHR10291 6 258 9.4E-115 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 DC74_RS25480 22e4a189ec4c28a2e537e894c7b0baf8 259 SUPERFAMILY SSF64005 25 253 7.59E-75 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 DC74_RS25480 22e4a189ec4c28a2e537e894c7b0baf8 259 Pfam PF01255 Putative undecaprenyl diphosphate synthase 37 258 5.2E-71 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 DC74_RS36585 85180c3e9e31935e0af0b16c27a91837 184 SUPERFAMILY SSF56214 75 146 1.7E-10 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS36585 85180c3e9e31935e0af0b16c27a91837 184 Gene3D G3DSA:3.90.470.20 11 79 4.4E-10 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS36585 85180c3e9e31935e0af0b16c27a91837 184 PANTHER PTHR12215:SF10 12 141 3.2E-12 T 23-04-2016 DC74_RS36585 85180c3e9e31935e0af0b16c27a91837 184 PANTHER PTHR12215 12 141 3.2E-12 T 23-04-2016 DC74_RS36585 85180c3e9e31935e0af0b16c27a91837 184 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 75 132 1.3E-5 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS36585 85180c3e9e31935e0af0b16c27a91837 184 SUPERFAMILY SSF56214 11 70 2.22E-9 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS36585 85180c3e9e31935e0af0b16c27a91837 184 Gene3D G3DSA:3.90.470.20 80 136 4.9E-8 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS36950 f094b52575466d419ab7ce6219397f52 238 Pfam PF04471 Restriction endonuclease 114 230 2.5E-21 T 23-04-2016 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 DC74_RS36950 f094b52575466d419ab7ce6219397f52 238 Gene3D G3DSA:3.40.1350.10 109 230 2.2E-23 T 23-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 DC74_RS36950 f094b52575466d419ab7ce6219397f52 238 PANTHER PTHR30015 1 237 1.7E-19 T 23-04-2016 DC74_RS36950 f094b52575466d419ab7ce6219397f52 238 SUPERFAMILY SSF52980 117 230 2.09E-13 T 23-04-2016 IPR011335 Restriction endonuclease type II-like DC74_RS13120 07ab304935ade747b2cc5f645880bc40 236 Pfam PF13829 Domain of unknown function (DUF4191) 14 230 4.4E-81 T 23-04-2016 IPR025445 Protein of unknown function DUF4191 DC74_RS13120 07ab304935ade747b2cc5f645880bc40 236 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 18 214 7.0E-83 T 23-04-2016 DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 Gene3D G3DSA:3.40.50.300 18 251 9.6E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 Pfam PF00005 ABC transporter 29 177 1.9E-22 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 Pfam PF00005 ABC transporter 361 488 1.1E-19 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 SUPERFAMILY SSF52540 24 226 5.42E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 SMART SM00382 36 221 6.2E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 SMART SM00382 366 533 1.4E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 Gene3D G3DSA:3.40.50.300 360 523 3.9E-34 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 PANTHER PTHR19211:SF6 284 530 9.2E-205 T 23-04-2016 DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 PANTHER PTHR19211:SF6 9 258 9.2E-205 T 23-04-2016 DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 PANTHER PTHR19211 284 530 9.2E-205 T 23-04-2016 DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 PANTHER PTHR19211 9 258 9.2E-205 T 23-04-2016 DC74_RS10535 69df9ee945b1887b7e49c62c59fd5ff6 541 SUPERFAMILY SSF52540 360 523 1.8E-37 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29670 40208f8d4ab831bd8ea22b323ad279a5 509 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 79 496 1.1E-41 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 DC74_RS29670 40208f8d4ab831bd8ea22b323ad279a5 509 SUPERFAMILY SSF47413 4 65 9.12E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS29670 40208f8d4ab831bd8ea22b323ad279a5 509 Gene3D G3DSA:3.65.10.10 92 292 2.4E-38 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 DC74_RS29670 40208f8d4ab831bd8ea22b323ad279a5 509 SUPERFAMILY SSF55205 74 506 3.27E-93 T 23-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 DC74_RS29670 40208f8d4ab831bd8ea22b323ad279a5 509 PANTHER PTHR21090:SF4 38 509 1.1E-112 T 23-04-2016 DC74_RS29670 40208f8d4ab831bd8ea22b323ad279a5 509 Gene3D G3DSA:1.10.260.40 3 66 2.8E-20 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS29670 40208f8d4ab831bd8ea22b323ad279a5 509 Gene3D G3DSA:3.65.10.10 293 504 2.8E-39 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 DC74_RS29670 40208f8d4ab831bd8ea22b323ad279a5 509 PANTHER PTHR21090 38 509 1.1E-112 T 23-04-2016 DC74_RS29670 40208f8d4ab831bd8ea22b323ad279a5 509 Pfam PF01381 Helix-turn-helix 13 63 2.9E-14 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS29670 40208f8d4ab831bd8ea22b323ad279a5 509 SMART SM00530 12 67 1.2E-14 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 Pfam PF00106 short chain dehydrogenase 3 188 1.4E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 Gene3D G3DSA:3.40.50.720 3 218 1.0E-57 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 PIRSF PIRSF000126 1 253 1.8E-65 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 SUPERFAMILY SSF51735 3 228 3.78E-56 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 PANTHER PTHR24322 6 180 2.4E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 PANTHER PTHR24322:SF513 6 180 2.4E-44 T 23-04-2016 DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 179 0.0028 T 23-04-2016 DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 4.2E-28 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.2E-28 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.2E-28 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.2E-28 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 4.2E-28 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 9.1E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 9.1E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18470 45ecd1e487d1b62a673863e33f2a0657 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 9.1E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02955 89fef911ba55069c5d900a561c8de543 191 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 3.4E-11 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS02955 89fef911ba55069c5d900a561c8de543 191 PANTHER PTHR33169:SF4 1 182 1.3E-45 T 23-04-2016 DC74_RS02955 89fef911ba55069c5d900a561c8de543 191 PANTHER PTHR33169 1 182 1.3E-45 T 23-04-2016 DC74_RS02955 89fef911ba55069c5d900a561c8de543 191 Pfam PF10400 Virulence activator alpha C-term 92 180 1.8E-18 T 23-04-2016 IPR018309 Transcription regulator PadR, C-terminal DC74_RS02955 89fef911ba55069c5d900a561c8de543 191 Gene3D G3DSA:1.10.10.10 1 84 1.8E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02955 89fef911ba55069c5d900a561c8de543 191 SUPERFAMILY SSF46785 3 180 1.02E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29050 056ffd1f261f6bc182756d92bd358741 814 PANTHER PTHR10169 11 756 3.6E-237 T 23-04-2016 DC74_RS29050 056ffd1f261f6bc182756d92bd358741 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 737 769 0.0078 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 DC74_RS29050 056ffd1f261f6bc182756d92bd358741 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 667 712 1.0E-6 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 DC74_RS29050 056ffd1f261f6bc182756d92bd358741 814 SUPERFAMILY SSF101904 513 793 3.01E-41 T 23-04-2016 DC74_RS29050 056ffd1f261f6bc182756d92bd358741 814 Gene3D G3DSA:3.90.199.10 41 246 1.9E-110 T 23-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 DC74_RS29050 056ffd1f261f6bc182756d92bd358741 814 Gene3D G3DSA:3.90.199.10 345 410 1.9E-110 T 23-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 DC74_RS29050 056ffd1f261f6bc182756d92bd358741 814 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 42 478 2.1E-147 T 23-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29050 056ffd1f261f6bc182756d92bd358741 814 Gene3D G3DSA:3.30.1360.40 247 344 1.0E-27 T 23-04-2016 IPR024946 Arginine repressor C-terminal-like domain DC74_RS29050 056ffd1f261f6bc182756d92bd358741 814 Gene3D G3DSA:2.120.10.90 513 800 7.0E-42 T 23-04-2016 DC74_RS29050 056ffd1f261f6bc182756d92bd358741 814 SUPERFAMILY SSF56719 41 498 9.94E-164 T 23-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 DC74_RS29050 056ffd1f261f6bc182756d92bd358741 814 SMART SM00434 21 476 9.4E-255 T 23-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS29050 056ffd1f261f6bc182756d92bd358741 814 PANTHER PTHR10169:SF48 11 756 3.6E-237 T 23-04-2016 DC74_RS04455 1b9b409913bf8616d5376ad7903b5374 205 PANTHER PTHR33798:SF1 5 199 6.0E-59 T 23-04-2016 DC74_RS04455 1b9b409913bf8616d5376ad7903b5374 205 PANTHER PTHR33798 5 199 6.0E-59 T 23-04-2016 DC74_RS04455 1b9b409913bf8616d5376ad7903b5374 205 SUPERFAMILY SSF50475 3 185 9.7E-50 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS04455 1b9b409913bf8616d5376ad7903b5374 205 SMART SM00903 21 165 3.2E-18 T 23-04-2016 IPR002563 Flavin reductase like domain GO:0010181 DC74_RS04455 1b9b409913bf8616d5376ad7903b5374 205 Gene3D G3DSA:2.30.110.10 4 187 2.0E-62 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS04455 1b9b409913bf8616d5376ad7903b5374 205 Pfam PF01613 Flavin reductase like domain 24 158 1.9E-23 T 23-04-2016 IPR002563 Flavin reductase like domain GO:0010181 DC74_RS23100 b118bc3420bc32be39285e6e9c19f1a0 143 SUPERFAMILY SSF48403 32 139 3.26E-20 T 23-04-2016 IPR020683 Ankyrin repeat-containing domain DC74_RS23100 b118bc3420bc32be39285e6e9c19f1a0 143 PANTHER PTHR24124 17 130 1.8E-47 T 23-04-2016 DC74_RS23100 b118bc3420bc32be39285e6e9c19f1a0 143 SMART SM00248 57 86 0.0024 T 23-04-2016 IPR002110 Ankyrin repeat GO:0005515 DC74_RS23100 b118bc3420bc32be39285e6e9c19f1a0 143 SMART SM00248 90 119 0.087 T 23-04-2016 IPR002110 Ankyrin repeat GO:0005515 DC74_RS23100 b118bc3420bc32be39285e6e9c19f1a0 143 Pfam PF12796 Ankyrin repeats (3 copies) 33 118 2.5E-11 T 23-04-2016 IPR020683 Ankyrin repeat-containing domain DC74_RS23100 b118bc3420bc32be39285e6e9c19f1a0 143 PANTHER PTHR24124:SF9 17 130 1.8E-47 T 23-04-2016 DC74_RS23100 b118bc3420bc32be39285e6e9c19f1a0 143 Gene3D G3DSA:1.25.40.20 31 119 3.0E-21 T 23-04-2016 IPR020683 Ankyrin repeat-containing domain DC74_RS10060 b98b5d2bc53096b3fb80060e6db9b322 698 Gene3D G3DSA:1.25.40.10 469 675 1.5E-22 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS10060 b98b5d2bc53096b3fb80060e6db9b322 698 Pfam PF13191 AAA ATPase domain 34 99 4.0E-8 T 23-04-2016 DC74_RS10060 b98b5d2bc53096b3fb80060e6db9b322 698 PANTHER PTHR22845 18 373 1.4E-55 T 23-04-2016 DC74_RS10060 b98b5d2bc53096b3fb80060e6db9b322 698 SUPERFAMILY SSF48452 470 673 6.32E-19 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS10060 b98b5d2bc53096b3fb80060e6db9b322 698 Gene3D G3DSA:3.40.50.300 47 128 1.1E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10060 b98b5d2bc53096b3fb80060e6db9b322 698 PANTHER PTHR22845:SF4 18 373 1.4E-55 T 23-04-2016 DC74_RS10060 b98b5d2bc53096b3fb80060e6db9b322 698 Pfam PF13424 Tetratricopeptide repeat 489 545 6.3E-9 T 23-04-2016 DC74_RS10060 b98b5d2bc53096b3fb80060e6db9b322 698 SUPERFAMILY SSF52540 21 279 8.54E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33370 148d9c2205c8d3d3117cbc5af4e705fd 304 Gene3D G3DSA:3.40.50.1820 172 303 2.7E-46 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS33370 148d9c2205c8d3d3117cbc5af4e705fd 304 Gene3D G3DSA:3.40.50.1820 8 136 2.7E-46 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS33370 148d9c2205c8d3d3117cbc5af4e705fd 304 Pfam PF12146 Serine aminopeptidase, S33 25 288 2.1E-45 T 23-04-2016 IPR022742 Serine aminopeptidase, S33 DC74_RS33370 148d9c2205c8d3d3117cbc5af4e705fd 304 SUPERFAMILY SSF53474 7 304 4.71E-35 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS33370 148d9c2205c8d3d3117cbc5af4e705fd 304 PANTHER PTHR11614 9 304 3.5E-43 T 23-04-2016 DC74_RS23170 373bada3cddd60f95ef520c7e84c3d30 281 SMART SM00450 146 273 4.0E-19 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS23170 373bada3cddd60f95ef520c7e84c3d30 281 SMART SM00450 8 122 2.4E-20 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS23170 373bada3cddd60f95ef520c7e84c3d30 281 PANTHER PTHR11364 1 281 1.3E-184 T 23-04-2016 DC74_RS23170 373bada3cddd60f95ef520c7e84c3d30 281 ProSitePatterns PS00683 Rhodanese C-terminal signature. 257 267 - T 23-04-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 DC74_RS23170 373bada3cddd60f95ef520c7e84c3d30 281 Gene3D G3DSA:3.40.250.10 155 276 4.3E-31 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS23170 373bada3cddd60f95ef520c7e84c3d30 281 Pfam PF00581 Rhodanese-like domain 10 118 8.0E-18 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS23170 373bada3cddd60f95ef520c7e84c3d30 281 Pfam PF00581 Rhodanese-like domain 151 268 1.2E-14 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS23170 373bada3cddd60f95ef520c7e84c3d30 281 Gene3D G3DSA:3.40.250.10 4 139 6.4E-37 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS23170 373bada3cddd60f95ef520c7e84c3d30 281 SUPERFAMILY SSF52821 151 278 6.94E-32 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS23170 373bada3cddd60f95ef520c7e84c3d30 281 SUPERFAMILY SSF52821 4 132 1.57E-35 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS23170 373bada3cddd60f95ef520c7e84c3d30 281 PANTHER PTHR11364:SF10 1 281 1.3E-184 T 23-04-2016 DC74_RS21790 c7de880eee65c136a02cfeaf7081a3c5 264 PANTHER PTHR10245:SF7 5 261 1.1E-56 T 23-04-2016 DC74_RS21790 c7de880eee65c136a02cfeaf7081a3c5 264 PANTHER PTHR10245 5 261 1.1E-56 T 23-04-2016 DC74_RS21790 c7de880eee65c136a02cfeaf7081a3c5 264 SMART SM00530 8 63 1.2E-11 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS21790 c7de880eee65c136a02cfeaf7081a3c5 264 SUPERFAMILY SSF47413 4 58 5.09E-12 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS21790 c7de880eee65c136a02cfeaf7081a3c5 264 Pfam PF13560 Helix-turn-helix domain 6 58 1.2E-12 T 23-04-2016 DC74_RS21790 c7de880eee65c136a02cfeaf7081a3c5 264 Gene3D G3DSA:1.10.260.40 5 58 5.7E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS12640 b76535b47cea10aef7bf7ee8cbebe926 502 Pfam PF01593 Flavin containing amine oxidoreductase 9 286 2.2E-16 T 23-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 DC74_RS12640 b76535b47cea10aef7bf7ee8cbebe926 502 PANTHER PTHR10668 1 494 5.8E-113 T 23-04-2016 DC74_RS12640 b76535b47cea10aef7bf7ee8cbebe926 502 Gene3D G3DSA:3.50.50.60 1 49 3.9E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12640 b76535b47cea10aef7bf7ee8cbebe926 502 Gene3D G3DSA:3.50.50.60 175 176 3.9E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12640 b76535b47cea10aef7bf7ee8cbebe926 502 Gene3D G3DSA:3.50.50.60 440 492 3.9E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12640 b76535b47cea10aef7bf7ee8cbebe926 502 Gene3D G3DSA:3.50.50.60 82 83 3.9E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12640 b76535b47cea10aef7bf7ee8cbebe926 502 Gene3D G3DSA:3.50.50.60 214 294 3.9E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12640 b76535b47cea10aef7bf7ee8cbebe926 502 SUPERFAMILY SSF51905 455 493 4.77E-46 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12640 b76535b47cea10aef7bf7ee8cbebe926 502 SUPERFAMILY SSF51905 1 328 4.77E-46 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12640 b76535b47cea10aef7bf7ee8cbebe926 502 PANTHER PTHR10668:SF75 1 494 5.8E-113 T 23-04-2016 DC74_RS38900 c01783f8f83e33daee20fd8a783e5112 254 Gene3D G3DSA:1.20.950.20 6 216 8.0E-82 T 23-04-2016 DC74_RS38900 c01783f8f83e33daee20fd8a783e5112 254 SUPERFAMILY SSF103501 6 224 5.1E-63 T 23-04-2016 IPR023234 NarG-like domain DC74_RS38900 c01783f8f83e33daee20fd8a783e5112 254 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 7 224 9.9E-59 T 23-04-2016 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 DC74_RS38900 c01783f8f83e33daee20fd8a783e5112 254 PANTHER PTHR30598:SF3 2 245 2.8E-106 T 23-04-2016 DC74_RS38900 c01783f8f83e33daee20fd8a783e5112 254 Pfam PF02665 Nitrate reductase gamma subunit 8 224 6.5E-79 T 23-04-2016 IPR023234 NarG-like domain DC74_RS38900 c01783f8f83e33daee20fd8a783e5112 254 PANTHER PTHR30598 2 245 2.8E-106 T 23-04-2016 DC74_RS23190 231138d01fa5cf7e4f5896f9acf17f3d 577 SUPERFAMILY SSF52540 325 570 4.58E-82 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23190 231138d01fa5cf7e4f5896f9acf17f3d 577 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS23190 231138d01fa5cf7e4f5896f9acf17f3d 577 SUPERFAMILY SSF90123 9 315 2.09E-72 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS23190 231138d01fa5cf7e4f5896f9acf17f3d 577 Gene3D G3DSA:3.40.50.300 334 564 1.3E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23190 231138d01fa5cf7e4f5896f9acf17f3d 577 Pfam PF00005 ABC transporter 351 498 2.2E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS23190 231138d01fa5cf7e4f5896f9acf17f3d 577 PANTHER PTHR24221 4 575 4.4E-232 T 23-04-2016 DC74_RS23190 231138d01fa5cf7e4f5896f9acf17f3d 577 PANTHER PTHR24221:SF190 4 575 4.4E-232 T 23-04-2016 DC74_RS23190 231138d01fa5cf7e4f5896f9acf17f3d 577 Pfam PF00664 ABC transporter transmembrane region 19 287 2.6E-44 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS23190 231138d01fa5cf7e4f5896f9acf17f3d 577 SMART SM00382 360 546 9.3E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS23190 231138d01fa5cf7e4f5896f9acf17f3d 577 Gene3D G3DSA:1.20.1560.10 10 320 1.4E-65 T 23-04-2016 DC74_RS20370 e942918ab075562afd136d008762bfd8 347 Gene3D G3DSA:3.90.1200.10 113 330 2.5E-21 T 23-04-2016 DC74_RS20370 e942918ab075562afd136d008762bfd8 347 Gene3D G3DSA:3.30.200.20 15 110 1.3E-15 T 23-04-2016 DC74_RS20370 e942918ab075562afd136d008762bfd8 347 Pfam PF01636 Phosphotransferase enzyme family 34 283 1.2E-28 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS20370 e942918ab075562afd136d008762bfd8 347 SUPERFAMILY SSF56112 14 335 5.98E-45 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS21445 c78b61c633405e7067a72e788fba882d 308 Pfam PF00589 Phage integrase family 144 289 2.4E-8 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS21445 c78b61c633405e7067a72e788fba882d 308 PANTHER PTHR30349:SF20 144 304 3.8E-17 T 23-04-2016 DC74_RS21445 c78b61c633405e7067a72e788fba882d 308 Gene3D G3DSA:1.10.443.10 144 297 6.2E-20 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS21445 c78b61c633405e7067a72e788fba882d 308 PANTHER PTHR30349 144 304 3.8E-17 T 23-04-2016 DC74_RS21445 c78b61c633405e7067a72e788fba882d 308 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 15 63 1.8E-7 T 23-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 DC74_RS21445 c78b61c633405e7067a72e788fba882d 308 Gene3D G3DSA:1.10.150.130 16 134 7.5E-12 T 23-04-2016 IPR023109 Integrase/recombinase, N-terminal DC74_RS21445 c78b61c633405e7067a72e788fba882d 308 SUPERFAMILY SSF56349 92 297 2.56E-34 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DC74_RS21445 c78b61c633405e7067a72e788fba882d 308 SUPERFAMILY SSF56349 15 63 2.56E-34 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DC74_RS27185 65aa318d35f2a8590f62b264e79d4aba 116 PANTHER PTHR40077 2 114 1.7E-18 T 23-04-2016 DC74_RS27185 65aa318d35f2a8590f62b264e79d4aba 116 Pfam PF12823 Domain of unknown function (DUF3817) 9 97 1.9E-15 T 23-04-2016 IPR023845 Domain of unknown function DUF3817, transmembrane DC74_RS27185 65aa318d35f2a8590f62b264e79d4aba 116 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 13 95 2.0E-18 T 23-04-2016 IPR023845 Domain of unknown function DUF3817, transmembrane DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 SUPERFAMILY SSF50465 301 391 1.41E-24 T 23-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 Pfam PF03144 Elongation factor Tu domain 2 224 291 6.5E-12 T 23-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 SUPERFAMILY SSF50447 204 297 3.53E-24 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 Pfam PF03143 Elongation factor Tu C-terminal domain 297 389 3.7E-18 T 23-04-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 Gene3D G3DSA:2.40.30.10 316 389 2.7E-28 T 23-04-2016 DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 Gene3D G3DSA:3.40.50.300 8 212 8.3E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 23-04-2016 IPR031157 Tr-type G domain, conserved site DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.4E-22 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.4E-22 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.4E-22 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.4E-22 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.4E-22 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 Pfam PF00009 Elongation factor Tu GTP binding domain 10 200 4.0E-52 T 23-04-2016 DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 PANTHER PTHR23115 1 389 2.8E-190 T 23-04-2016 DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 391 8.0E-167 T 23-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 SUPERFAMILY SSF52540 8 225 1.84E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 149 7.3E-12 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 Gene3D G3DSA:2.40.30.10 213 315 2.6E-39 T 23-04-2016 DC74_RS35055 b862292554fb25a2de30454cfcdff9a0 391 PANTHER PTHR23115:SF112 1 389 2.8E-190 T 23-04-2016 DC74_RS38520 e54338817a2c1799f60640b0aee282fd 221 Gene3D G3DSA:1.10.10.10 8 69 2.6E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38520 e54338817a2c1799f60640b0aee282fd 221 SUPERFAMILY SSF46785 10 100 4.7E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38520 e54338817a2c1799f60640b0aee282fd 221 Pfam PF12840 Helix-turn-helix domain 12 68 2.2E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36935 6fc62b34ce4582d9cb25ebea63bddfbb 195 SUPERFAMILY SSF46894 120 194 2.86E-17 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS36935 6fc62b34ce4582d9cb25ebea63bddfbb 195 SUPERFAMILY SSF52172 2 119 1.04E-10 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS36935 6fc62b34ce4582d9cb25ebea63bddfbb 195 Gene3D G3DSA:1.10.10.10 115 195 4.2E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36935 6fc62b34ce4582d9cb25ebea63bddfbb 195 PANTHER PTHR26402 2 195 8.9E-44 T 23-04-2016 DC74_RS36935 6fc62b34ce4582d9cb25ebea63bddfbb 195 Gene3D G3DSA:3.40.50.2300 2 114 1.8E-9 T 23-04-2016 DC74_RS36935 6fc62b34ce4582d9cb25ebea63bddfbb 195 Pfam PF00196 Bacterial regulatory proteins, luxR family 134 187 6.4E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS36935 6fc62b34ce4582d9cb25ebea63bddfbb 195 ProSitePatterns PS00622 LuxR-type HTH domain signature. 149 176 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS36935 6fc62b34ce4582d9cb25ebea63bddfbb 195 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 165 2.1E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS36935 6fc62b34ce4582d9cb25ebea63bddfbb 195 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 177 2.1E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS36935 6fc62b34ce4582d9cb25ebea63bddfbb 195 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 135 149 2.1E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS36935 6fc62b34ce4582d9cb25ebea63bddfbb 195 PANTHER PTHR26402:SF137 2 195 8.9E-44 T 23-04-2016 DC74_RS36935 6fc62b34ce4582d9cb25ebea63bddfbb 195 SMART SM00421 132 189 2.3E-18 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 5.3E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 5.3E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 5.3E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 16 5.3E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 SUPERFAMILY SSF51735 1 229 1.79E-61 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 PANTHER PTHR24322 4 138 1.3E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 PANTHER PTHR24322 154 185 1.3E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 Pfam PF00106 short chain dehydrogenase 1 195 1.7E-49 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.5E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.5E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.5E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS13450 15b61712c47089520876bf4614dc48ce 249 Gene3D G3DSA:3.40.50.720 1 237 1.5E-65 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 SUPERFAMILY SSF89082 160 251 3.4E-29 T 23-04-2016 IPR012925 TipAS antibiotic-recognition domain DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 PANTHER PTHR30204 1 245 2.8E-75 T 23-04-2016 DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 SMART SM00422 3 72 6.8E-33 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 Gene3D G3DSA:1.10.1660.10 58 107 1.6E-10 T 23-04-2016 DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 SUPERFAMILY SSF46955 3 104 4.4E-30 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 PANTHER PTHR30204:SF5 1 245 2.8E-75 T 23-04-2016 DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 Pfam PF07739 TipAS antibiotic-recognition domain 132 246 1.8E-36 T 23-04-2016 IPR012925 TipAS antibiotic-recognition domain DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 2.2E-9 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 2.2E-9 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 2.2E-9 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 Gene3D G3DSA:1.10.490.50 160 251 4.0E-34 T 23-04-2016 IPR012925 TipAS antibiotic-recognition domain DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 Pfam PF13411 MerR HTH family regulatory protein 3 70 7.2E-17 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 Gene3D G3DSA:1.10.1660.10 3 57 7.0E-26 T 23-04-2016 DC74_RS22395 99cc614769a6e1e615631aaae9a475e3 252 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS02325 88392f085905feb1c11929558ebe0ede 195 PANTHER PTHR33711:SF2 7 194 6.3E-46 T 23-04-2016 DC74_RS02325 88392f085905feb1c11929558ebe0ede 195 Gene3D G3DSA:2.60.130.10 6 193 5.9E-50 T 23-04-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 DC74_RS02325 88392f085905feb1c11929558ebe0ede 195 SUPERFAMILY SSF49482 5 193 4.45E-36 T 23-04-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 DC74_RS02325 88392f085905feb1c11929558ebe0ede 195 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 9 193 2.0E-44 T 23-04-2016 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|UniPathway: UPA00157 DC74_RS02325 88392f085905feb1c11929558ebe0ede 195 PANTHER PTHR33711 7 194 6.3E-46 T 23-04-2016 DC74_RS02030 2e06601319ee901e98d5ac4a9aee16fa 269 PANTHER PTHR22981 13 220 1.9E-41 T 23-04-2016 DC74_RS02030 2e06601319ee901e98d5ac4a9aee16fa 269 SUPERFAMILY SSF48179 161 256 2.15E-15 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS02030 2e06601319ee901e98d5ac4a9aee16fa 269 Gene3D G3DSA:3.40.50.720 3 161 5.3E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02030 2e06601319ee901e98d5ac4a9aee16fa 269 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 160 1.0E-24 T 23-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 DC74_RS02030 2e06601319ee901e98d5ac4a9aee16fa 269 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 163 251 3.5E-11 T 23-04-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 DC74_RS02030 2e06601319ee901e98d5ac4a9aee16fa 269 SUPERFAMILY SSF51735 3 160 3.31E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02030 2e06601319ee901e98d5ac4a9aee16fa 269 PIRSF PIRSF000103 1 266 4.2E-41 T 23-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 DC74_RS02030 2e06601319ee901e98d5ac4a9aee16fa 269 Gene3D G3DSA:1.10.1040.10 163 265 2.2E-13 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS39985 f84aff4be469d546b47ce3ec359eba8f 404 Pfam PF13560 Helix-turn-helix domain 2 61 2.5E-14 T 23-04-2016 DC74_RS39985 f84aff4be469d546b47ce3ec359eba8f 404 SMART SM00530 6 62 8.9E-8 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS39985 f84aff4be469d546b47ce3ec359eba8f 404 SUPERFAMILY SSF47413 1 57 1.44E-12 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS39985 f84aff4be469d546b47ce3ec359eba8f 404 Gene3D G3DSA:1.10.260.40 3 71 1.8E-12 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS33315 cde26d125e6345c3a644c07b1106ea3f 305 Gene3D G3DSA:3.40.1190.20 1 282 6.9E-45 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS33315 cde26d125e6345c3a644c07b1106ea3f 305 Pfam PF00294 pfkB family carbohydrate kinase 179 273 6.5E-19 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS33315 cde26d125e6345c3a644c07b1106ea3f 305 SUPERFAMILY SSF53613 1 274 2.34E-44 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS33315 cde26d125e6345c3a644c07b1106ea3f 305 PANTHER PTHR10584 1 282 4.5E-33 T 23-04-2016 DC74_RS00540 b666e6d6c5f5806d0a53426937d9ba9b 333 PANTHER PTHR30146 4 333 3.5E-53 T 23-04-2016 DC74_RS00540 b666e6d6c5f5806d0a53426937d9ba9b 333 Gene3D G3DSA:3.40.50.2300 171 330 2.3E-19 T 23-04-2016 DC74_RS00540 b666e6d6c5f5806d0a53426937d9ba9b 333 Gene3D G3DSA:3.40.50.2300 58 170 1.6E-16 T 23-04-2016 DC74_RS00540 b666e6d6c5f5806d0a53426937d9ba9b 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 8.3E-18 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS00540 b666e6d6c5f5806d0a53426937d9ba9b 333 Pfam PF13377 Periplasmic binding protein-like domain 170 329 1.0E-18 T 23-04-2016 DC74_RS00540 b666e6d6c5f5806d0a53426937d9ba9b 333 Gene3D G3DSA:1.10.260.40 6 57 1.1E-24 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS00540 b666e6d6c5f5806d0a53426937d9ba9b 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS00540 b666e6d6c5f5806d0a53426937d9ba9b 333 SUPERFAMILY SSF47413 5 63 1.26E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS00540 b666e6d6c5f5806d0a53426937d9ba9b 333 SUPERFAMILY SSF53822 66 323 1.83E-27 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS00540 b666e6d6c5f5806d0a53426937d9ba9b 333 SMART SM00354 5 75 4.4E-25 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS05295 f8bd25a0f9dc0dc54e275bf0e02b6cb0 180 PANTHER PTHR11002 1 176 3.4E-12 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS05295 f8bd25a0f9dc0dc54e275bf0e02b6cb0 180 Gene3D G3DSA:3.40.1050.10 7 177 3.4E-24 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS05295 f8bd25a0f9dc0dc54e275bf0e02b6cb0 180 Pfam PF00484 Carbonic anhydrase 36 105 6.5E-7 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS05295 f8bd25a0f9dc0dc54e275bf0e02b6cb0 180 SUPERFAMILY SSF53056 6 176 5.36E-21 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS05295 f8bd25a0f9dc0dc54e275bf0e02b6cb0 180 SMART SM00947 27 177 5.3E-7 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS05295 f8bd25a0f9dc0dc54e275bf0e02b6cb0 180 PANTHER PTHR11002:SF4 1 176 3.4E-12 T 23-04-2016 DC74_RS28430 ca29152a3cd454ebeb70af8f26d9bc2a 92 PANTHER PTHR34215:SF1 2 88 2.6E-21 T 23-04-2016 DC74_RS28430 ca29152a3cd454ebeb70af8f26d9bc2a 92 SUPERFAMILY SSF64376 9 80 2.62E-21 T 23-04-2016 IPR007393 Domain of unknown function DUF448 DC74_RS28430 ca29152a3cd454ebeb70af8f26d9bc2a 92 PANTHER PTHR34215 2 88 2.6E-21 T 23-04-2016 DC74_RS28430 ca29152a3cd454ebeb70af8f26d9bc2a 92 Gene3D G3DSA:3.30.1230.10 7 76 2.6E-23 T 23-04-2016 IPR007393 Domain of unknown function DUF448 DC74_RS28430 ca29152a3cd454ebeb70af8f26d9bc2a 92 Pfam PF04296 Protein of unknown function (DUF448) 13 73 4.2E-20 T 23-04-2016 IPR007393 Domain of unknown function DUF448 DC74_RS31645 6cc5fdfc57e62b5f57559a0ba29a2c92 294 SUPERFAMILY SSF53807 11 264 1.49E-18 T 23-04-2016 DC74_RS31645 6cc5fdfc57e62b5f57559a0ba29a2c92 294 Pfam PF01497 Periplasmic binding protein 56 256 7.5E-9 T 23-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 DC74_RS31645 6cc5fdfc57e62b5f57559a0ba29a2c92 294 Gene3D G3DSA:3.40.50.1980 23 136 3.1E-7 T 23-04-2016 DC74_RS31645 6cc5fdfc57e62b5f57559a0ba29a2c92 294 Gene3D G3DSA:3.40.50.1980 137 256 1.7E-6 T 23-04-2016 DC74_RS11910 6dd683beaedd2d85029d662381a2e6a9 246 Pfam PF07398 MDMPI C-terminal domain 159 238 1.3E-7 T 23-04-2016 IPR010872 MDMPI C-terminal DC74_RS11910 6dd683beaedd2d85029d662381a2e6a9 246 Gene3D G3DSA:1.20.120.450 11 122 5.8E-5 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS11910 6dd683beaedd2d85029d662381a2e6a9 246 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 227 8.1E-32 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS11910 6dd683beaedd2d85029d662381a2e6a9 246 SUPERFAMILY SSF55718 159 245 1.88E-11 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS11910 6dd683beaedd2d85029d662381a2e6a9 246 SUPERFAMILY SSF109854 3 156 2.29E-37 T 23-04-2016 DC74_RS11910 6dd683beaedd2d85029d662381a2e6a9 246 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 15 151 9.7E-24 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS20165 bcda6f75ece84af0db0a6be63767dc77 256 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 12 253 2.7E-48 T 23-04-2016 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 DC74_RS20165 bcda6f75ece84af0db0a6be63767dc77 256 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 13 238 3.6E-72 T 23-04-2016 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 DC74_RS20165 bcda6f75ece84af0db0a6be63767dc77 256 PANTHER PTHR36925 9 256 1.2E-74 T 23-04-2016 DC74_RS20165 bcda6f75ece84af0db0a6be63767dc77 256 Gene3D G3DSA:3.40.50.2300 192 239 1.6E-4 T 23-04-2016 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 527 1.7E-243 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 SUPERFAMILY SSF52029 184 376 3.44E-79 T 23-04-2016 IPR027409 GroEL-like apical domain DC74_RS18480 74c432016e2f65669394d262b036f99d 540 Gene3D G3DSA:3.50.7.10 195 370 1.3E-89 T 23-04-2016 IPR027409 GroEL-like apical domain DC74_RS18480 74c432016e2f65669394d262b036f99d 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 525 6.2E-93 T 23-04-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 Gene3D G3DSA:1.10.560.10 6 194 2.4E-43 T 23-04-2016 IPR027413 GroEL-like equatorial domain DC74_RS18480 74c432016e2f65669394d262b036f99d 540 SUPERFAMILY SSF54849 136 203 1.53E-24 T 23-04-2016 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 Gene3D G3DSA:1.10.560.10 371 518 1.3E-37 T 23-04-2016 IPR027413 GroEL-like equatorial domain DC74_RS18480 74c432016e2f65669394d262b036f99d 540 SUPERFAMILY SSF48592 6 133 6.83E-72 T 23-04-2016 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 SUPERFAMILY SSF48592 406 521 6.83E-72 T 23-04-2016 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 538 41.327 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 23-04-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 PRINTS PR00298 60kDa chaperonin signature 26 52 3.6E-71 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 PRINTS PR00298 60kDa chaperonin signature 350 375 3.6E-71 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 PRINTS PR00298 60kDa chaperonin signature 398 419 3.6E-71 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 PRINTS PR00298 60kDa chaperonin signature 268 291 3.6E-71 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 PRINTS PR00298 60kDa chaperonin signature 82 109 3.6E-71 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 DC74_RS18480 74c432016e2f65669394d262b036f99d 540 PANTHER PTHR11353 1 531 3.6E-217 T 23-04-2016 DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 Gene3D G3DSA:1.10.10.10 832 889 1.1E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 836 850 7.8E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 850 866 7.8E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 866 878 7.8E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 Pfam PF00196 Bacterial regulatory proteins, luxR family 835 888 1.7E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 SUPERFAMILY SSF52540 9 206 1.8E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 ProSitePatterns PS00622 LuxR-type HTH domain signature. 850 877 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 SUPERFAMILY SSF46894 823 889 1.6E-17 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 Gene3D G3DSA:3.40.50.300 12 53 7.1E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 Gene3D G3DSA:3.40.50.300 92 147 7.1E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 SMART SM00421 833 890 5.9E-20 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 PANTHER PTHR16305 854 885 1.5E-32 T 23-04-2016 DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 PANTHER PTHR16305 4 438 1.5E-32 T 23-04-2016 DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 SMART SM00382 8 185 0.0025 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS04650 e29d3469e20053a8172fbfee40ae1cab 893 Pfam PF13191 AAA ATPase domain 7 146 2.5E-17 T 23-04-2016 DC74_RS34850 e4b651de0a4f9dc6e8336baad624f58d 197 PANTHER PTHR40078:SF1 1 191 3.4E-48 T 23-04-2016 DC74_RS34850 e4b651de0a4f9dc6e8336baad624f58d 197 PANTHER PTHR40078 1 191 3.4E-48 T 23-04-2016 DC74_RS29185 ff37e06e3ccf6c84309b34365d253401 558 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 5 558 5.6E-204 T 23-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 DC74_RS29185 ff37e06e3ccf6c84309b34365d253401 558 Pfam PF03814 Potassium-transporting ATPase A subunit 14 557 9.1E-221 T 23-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 DC74_RS29185 ff37e06e3ccf6c84309b34365d253401 558 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 558 31.977 T 23-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 DC74_RS29185 ff37e06e3ccf6c84309b34365d253401 558 PANTHER PTHR30607 4 558 1.8E-284 T 23-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 DC74_RS29185 ff37e06e3ccf6c84309b34365d253401 558 PIRSF PIRSF001294 4 558 1.9E-212 T 23-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 DC74_RS30920 e2574a05ad4e9ee9851ba495ca43fa8a 352 SMART SM00331 116 330 1.1E-32 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS30920 e2574a05ad4e9ee9851ba495ca43fa8a 352 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 143 330 2.7E-45 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS30920 e2574a05ad4e9ee9851ba495ca43fa8a 352 SUPERFAMILY SSF81606 129 330 1.1E-6 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS30920 e2574a05ad4e9ee9851ba495ca43fa8a 352 PANTHER PTHR21021 81 339 3.4E-46 T 23-04-2016 DC74_RS38380 3ef76353b360d661bf95c692ce866b64 876 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 131 831 9.0E-237 T 23-04-2016 IPR012728 Non-ribosomal peptide synthetase, C-terminal DC74_RS38380 3ef76353b360d661bf95c692ce866b64 876 SUPERFAMILY SSF51161 229 343 7.21E-14 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS38380 3ef76353b360d661bf95c692ce866b64 876 SUPERFAMILY SSF47336 29 118 3.66E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38380 3ef76353b360d661bf95c692ce866b64 876 SUPERFAMILY SSF51161 701 832 8.46E-19 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS38380 3ef76353b360d661bf95c692ce866b64 876 SMART SM00823 Phosphopantetheine attachment site 31 103 0.0051 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS38380 3ef76353b360d661bf95c692ce866b64 876 Gene3D G3DSA:2.160.10.10 751 833 4.7E-25 T 23-04-2016 DC74_RS38380 3ef76353b360d661bf95c692ce866b64 876 Gene3D G3DSA:2.160.10.10 531 579 4.7E-25 T 23-04-2016 DC74_RS38380 3ef76353b360d661bf95c692ce866b64 876 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 785 810 0.0019 T 23-04-2016 IPR001451 Hexapeptide repeat DC74_RS38380 3ef76353b360d661bf95c692ce866b64 876 Gene3D G3DSA:2.160.10.10 191 343 3.9E-18 T 23-04-2016 DC74_RS38380 3ef76353b360d661bf95c692ce866b64 876 Pfam PF00550 Phosphopantetheine attachment site 35 99 1.3E-8 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS38380 3ef76353b360d661bf95c692ce866b64 876 Gene3D G3DSA:1.10.1200.10 28 101 7.2E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PANTHER PTHR24322:SF25 12 138 8.7E-56 T 23-04-2016 DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 Gene3D G3DSA:3.40.50.720 4 259 2.8E-68 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 258 7.3E-45 T 23-04-2016 DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PANTHER PTHR24322 12 138 8.7E-56 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.2E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.2E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.2E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.2E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.2E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.2E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.5E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.5E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.5E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PANTHER PTHR24322 154 186 8.7E-56 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 PANTHER PTHR24322:SF25 154 186 8.7E-56 T 23-04-2016 DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 SUPERFAMILY SSF51735 3 259 1.28E-63 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02845 2b71874f6f16a42075308520c04b252c 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS22825 c63ea5d283769803fe368768c91aaadf 192 SMART SM00823 Phosphopantetheine attachment site 11 70 0.0046 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS22825 c63ea5d283769803fe368768c91aaadf 192 Gene3D G3DSA:1.10.1200.10 7 67 2.2E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS22825 c63ea5d283769803fe368768c91aaadf 192 SUPERFAMILY SSF47336 7 72 6.41E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS22825 c63ea5d283769803fe368768c91aaadf 192 Pfam PF00550 Phosphopantetheine attachment site 14 71 1.7E-9 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS22305 2b64e7934f8b65feb02b69b363821a0e 65 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 3 63 16.996 T 23-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 DC74_RS22305 2b64e7934f8b65feb02b69b363821a0e 65 Pfam PF02416 mttA/Hcf106 family 8 56 6.8E-17 T 23-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 DC74_RS22305 2b64e7934f8b65feb02b69b363821a0e 65 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 6 51 7.0E-16 T 23-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 DC74_RS23570 75d48c713ba08a462f138fde156645b2 577 Pfam PF00367 phosphotransferase system, EIIB 13 43 1.3E-12 T 23-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 DC74_RS23570 75d48c713ba08a462f138fde156645b2 577 Gene3D G3DSA:3.30.1360.60 6 84 5.2E-22 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 DC74_RS23570 75d48c713ba08a462f138fde156645b2 577 PANTHER PTHR30175 10 80 8.3E-148 T 23-04-2016 DC74_RS23570 75d48c713ba08a462f138fde156645b2 577 PANTHER PTHR30175 143 520 8.3E-148 T 23-04-2016 DC74_RS23570 75d48c713ba08a462f138fde156645b2 577 SUPERFAMILY SSF55604 10 81 1.44E-16 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 DC74_RS23570 75d48c713ba08a462f138fde156645b2 577 Pfam PF02378 Phosphotransferase system, EIIC 176 444 1.3E-29 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 DC74_RS23570 75d48c713ba08a462f138fde156645b2 577 PANTHER PTHR30175:SF3 10 80 8.3E-148 T 23-04-2016 DC74_RS23570 75d48c713ba08a462f138fde156645b2 577 PANTHER PTHR30175:SF3 143 520 8.3E-148 T 23-04-2016 DC74_RS23570 75d48c713ba08a462f138fde156645b2 577 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 22 39 - T 23-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 DC74_RS22105 f53b1fc1a681f1af7a3d6570b72646ad 285 Gene3D G3DSA:1.10.3290.10 55 272 2.5E-6 T 23-04-2016 IPR003812 Fido domain DC74_RS25605 e825cbf002403063adc1dbadfa1bb8af 276 PANTHER PTHR40763 12 268 6.5E-70 T 23-04-2016 DC74_RS25605 e825cbf002403063adc1dbadfa1bb8af 276 PANTHER PTHR40763:SF1 12 268 6.5E-70 T 23-04-2016 DC74_RS25605 e825cbf002403063adc1dbadfa1bb8af 276 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 126 191 1.6E-11 T 23-04-2016 IPR024425 Cell wall-active antibiotics response 4TMS YvqF DC74_RS25605 e825cbf002403063adc1dbadfa1bb8af 276 Pfam PF08044 Domain of unknown function (DUF1707) 30 82 6.1E-23 T 23-04-2016 IPR012551 Protein of unknown function DUF1707 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 2.1E-35 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 2.1E-35 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 2.1E-35 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 2.1E-35 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 329 7.6E-126 T 23-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 SUPERFAMILY SSF52540 161 330 4.07E-48 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 23-04-2016 IPR006074 GTP1/OBG, conserved site GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 Pfam PF01018 GTP1/OBG 4 157 1.5E-52 T 23-04-2016 IPR006169 GTP1/OBG domain GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 Gene3D G3DSA:2.70.210.12 3 156 3.8E-49 T 23-04-2016 IPR006169 GTP1/OBG domain GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 SUPERFAMILY SSF102741 354 430 3.92E-19 T 23-04-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 Gene3D G3DSA:3.40.50.300 160 343 2.2E-48 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 SUPERFAMILY SSF82051 4 157 4.45E-47 T 23-04-2016 IPR006169 GTP1/OBG domain GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 356 429 6.2E-27 T 23-04-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 PANTHER PTHR11702 4 338 3.0E-135 T 23-04-2016 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 PANTHER PTHR11702 462 467 3.0E-135 T 23-04-2016 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 Hamap MF_01454 GTPase Obg [obg]. 3 330 44.354 T 23-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 Pfam PF01926 50S ribosome-binding GTPase 161 283 1.6E-22 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 PANTHER PTHR11702:SF3 4 338 3.0E-135 T 23-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 PANTHER PTHR11702:SF3 462 467 3.0E-135 T 23-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 DC74_RS15205 bd57f07313c58e75467207f30a092ca2 478 Pfam PF09269 Domain of unknown function (DUF1967) 356 428 9.5E-24 T 23-04-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 DC74_RS23820 b5f42d25ff1bbafc18d6e2bf8bfe633c 372 Gene3D G3DSA:3.40.640.10 20 266 3.0E-52 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS23820 b5f42d25ff1bbafc18d6e2bf8bfe633c 372 Pfam PF00266 Aminotransferase class-V 18 331 1.5E-19 T 23-04-2016 IPR000192 Aminotransferase class V domain DC74_RS23820 b5f42d25ff1bbafc18d6e2bf8bfe633c 372 PIRSF PIRSF000525 1 372 2.6E-76 T 23-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 DC74_RS23820 b5f42d25ff1bbafc18d6e2bf8bfe633c 372 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 5 372 23.111 T 23-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 DC74_RS23820 b5f42d25ff1bbafc18d6e2bf8bfe633c 372 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 11 371 3.3E-212 T 23-04-2016 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 DC74_RS23820 b5f42d25ff1bbafc18d6e2bf8bfe633c 372 Gene3D G3DSA:3.90.1150.10 268 368 2.6E-4 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS23820 b5f42d25ff1bbafc18d6e2bf8bfe633c 372 PANTHER PTHR21152 3 372 7.6E-178 T 23-04-2016 DC74_RS23820 b5f42d25ff1bbafc18d6e2bf8bfe633c 372 SUPERFAMILY SSF53383 12 369 1.5E-77 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS23820 b5f42d25ff1bbafc18d6e2bf8bfe633c 372 PANTHER PTHR21152:SF20 3 372 7.6E-178 T 23-04-2016 DC74_RS26335 56965e3c666d8307a595c56527f6d203 107 PANTHER PTHR30561:SF10 1 103 4.8E-60 T 23-04-2016 DC74_RS26335 56965e3c666d8307a595c56527f6d203 107 PANTHER PTHR30561 1 103 4.8E-60 T 23-04-2016 DC74_RS26335 56965e3c666d8307a595c56527f6d203 107 SUPERFAMILY SSF103481 6 105 1.27E-17 T 23-04-2016 DC74_RS26335 56965e3c666d8307a595c56527f6d203 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 3.1E-24 T 23-04-2016 IPR000390 Small multidrug resistance protein family GO:0016021 DC74_RS36805 40dbcfe0b7582570cd343a881f84a404 202 SUPERFAMILY SSF47413 11 73 3.38E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS36805 40dbcfe0b7582570cd343a881f84a404 202 Gene3D G3DSA:1.10.260.40 11 77 1.4E-20 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS36805 40dbcfe0b7582570cd343a881f84a404 202 PANTHER PTHR10245 1 191 4.1E-26 T 23-04-2016 DC74_RS36805 40dbcfe0b7582570cd343a881f84a404 202 SMART SM00530 16 71 1.4E-19 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS36805 40dbcfe0b7582570cd343a881f84a404 202 Gene3D G3DSA:2.60.120.10 127 186 1.5E-9 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS36805 40dbcfe0b7582570cd343a881f84a404 202 SUPERFAMILY SSF51182 109 182 4.62E-13 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS36805 40dbcfe0b7582570cd343a881f84a404 202 Pfam PF01381 Helix-turn-helix 17 71 1.4E-18 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS36805 40dbcfe0b7582570cd343a881f84a404 202 Pfam PF07883 Cupin domain 125 182 8.0E-10 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS23270 f2c40900d7083f96eab13ec34a11503d 438 Gene3D G3DSA:3.40.50.2000 191 404 5.0E-41 T 23-04-2016 DC74_RS23270 f2c40900d7083f96eab13ec34a11503d 438 Pfam PF13439 Glycosyltransferase Family 4 30 211 7.1E-33 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain DC74_RS23270 f2c40900d7083f96eab13ec34a11503d 438 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 11 427 2.4E-200 T 23-04-2016 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 DC74_RS23270 f2c40900d7083f96eab13ec34a11503d 438 PANTHER PTHR12526 2 431 1.2E-224 T 23-04-2016 DC74_RS23270 f2c40900d7083f96eab13ec34a11503d 438 SUPERFAMILY SSF53756 11 425 1.61E-85 T 23-04-2016 DC74_RS23270 f2c40900d7083f96eab13ec34a11503d 438 Pfam PF00534 Glycosyl transferases group 1 230 403 6.9E-34 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 DC74_RS23270 f2c40900d7083f96eab13ec34a11503d 438 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 10 430 52.684 T 23-04-2016 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 DC74_RS23270 f2c40900d7083f96eab13ec34a11503d 438 PANTHER PTHR12526:SF185 2 431 1.2E-224 T 23-04-2016 DC74_RS32185 7dcf4a5c55488580f07ef4e0b9197663 370 Gene3D G3DSA:3.20.20.70 18 233 2.0E-25 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS32185 7dcf4a5c55488580f07ef4e0b9197663 370 Pfam PF04055 Radical SAM superfamily 23 171 7.2E-12 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS32185 7dcf4a5c55488580f07ef4e0b9197663 370 SUPERFAMILY SSF102114 17 45 2.09E-22 T 23-04-2016 DC74_RS32185 7dcf4a5c55488580f07ef4e0b9197663 370 SUPERFAMILY SSF102114 74 244 2.09E-22 T 23-04-2016 DC74_RS21010 147a6ce2f5de5e5cd8b2b20bc74a391d 502 PANTHER PTHR30365:SF0 384 492 5.5E-211 T 23-04-2016 DC74_RS21010 147a6ce2f5de5e5cd8b2b20bc74a391d 502 PANTHER PTHR30365:SF0 1 360 5.5E-211 T 23-04-2016 DC74_RS21010 147a6ce2f5de5e5cd8b2b20bc74a391d 502 PANTHER PTHR30365 384 492 5.5E-211 T 23-04-2016 DC74_RS21010 147a6ce2f5de5e5cd8b2b20bc74a391d 502 PANTHER PTHR30365 1 360 5.5E-211 T 23-04-2016 DC74_RS21010 147a6ce2f5de5e5cd8b2b20bc74a391d 502 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 473 5.6E-178 T 23-04-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 DC74_RS30580 664503b35a4456d09c169a97f0733357 408 Gene3D G3DSA:1.20.1250.20 223 358 2.9E-11 T 23-04-2016 DC74_RS30580 664503b35a4456d09c169a97f0733357 408 Gene3D G3DSA:1.20.1250.20 21 200 1.5E-9 T 23-04-2016 DC74_RS30580 664503b35a4456d09c169a97f0733357 408 PANTHER PTHR23513 25 400 5.4E-15 T 23-04-2016 DC74_RS30580 664503b35a4456d09c169a97f0733357 408 SUPERFAMILY SSF103473 21 397 4.45E-26 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS30580 664503b35a4456d09c169a97f0733357 408 Pfam PF07690 Major Facilitator Superfamily 24 352 1.8E-14 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS03305 55e8e1bce09a1cd3ac97b92ab892d722 321 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 270 312 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS03305 55e8e1bce09a1cd3ac97b92ab892d722 321 PANTHER PTHR11019:SF68 66 320 6.1E-91 T 23-04-2016 DC74_RS03305 55e8e1bce09a1cd3ac97b92ab892d722 321 SUPERFAMILY SSF46689 270 319 2.06E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03305 55e8e1bce09a1cd3ac97b92ab892d722 321 SMART SM00342 233 316 1.3E-24 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS03305 55e8e1bce09a1cd3ac97b92ab892d722 321 Gene3D G3DSA:3.40.50.880 10 222 2.8E-46 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS03305 55e8e1bce09a1cd3ac97b92ab892d722 321 Pfam PF01965 DJ-1/PfpI family 10 179 3.4E-14 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS03305 55e8e1bce09a1cd3ac97b92ab892d722 321 Pfam PF12833 Helix-turn-helix domain 240 317 4.2E-19 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS03305 55e8e1bce09a1cd3ac97b92ab892d722 321 Gene3D G3DSA:1.10.10.60 271 318 1.7E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03305 55e8e1bce09a1cd3ac97b92ab892d722 321 SUPERFAMILY SSF46689 218 266 4.93E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03305 55e8e1bce09a1cd3ac97b92ab892d722 321 PANTHER PTHR11019 66 320 6.1E-91 T 23-04-2016 DC74_RS03305 55e8e1bce09a1cd3ac97b92ab892d722 321 Gene3D G3DSA:1.10.10.60 223 270 3.7E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03305 55e8e1bce09a1cd3ac97b92ab892d722 321 SUPERFAMILY SSF52317 8 200 1.81E-41 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS06225 55077b6852d29257d23588fc83690095 769 PANTHER PTHR30519:SF0 8 769 0.0 T 23-04-2016 DC74_RS06225 55077b6852d29257d23588fc83690095 769 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 13 323 2.9E-115 T 23-04-2016 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 DC74_RS06225 55077b6852d29257d23588fc83690095 769 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 16 768 0.0 T 23-04-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 DC74_RS06225 55077b6852d29257d23588fc83690095 769 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 10 768 35.019 T 23-04-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 DC74_RS06225 55077b6852d29257d23588fc83690095 769 PANTHER PTHR30519 8 769 0.0 T 23-04-2016 DC74_RS06225 55077b6852d29257d23588fc83690095 769 SUPERFAMILY SSF51726 12 404 1.1E-102 T 23-04-2016 DC74_RS06225 55077b6852d29257d23588fc83690095 769 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 441 763 9.2E-143 T 23-04-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 DC74_RS06225 55077b6852d29257d23588fc83690095 769 Gene3D G3DSA:3.20.20.210 403 769 1.0E-125 T 23-04-2016 DC74_RS06225 55077b6852d29257d23588fc83690095 769 PIRSF PIRSF000382 9 769 0.0 T 23-04-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 DC74_RS06225 55077b6852d29257d23588fc83690095 769 SUPERFAMILY SSF51726 406 767 7.98E-111 T 23-04-2016 DC74_RS06225 55077b6852d29257d23588fc83690095 769 Gene3D G3DSA:3.20.20.210 12 399 2.5E-139 T 23-04-2016 DC74_RS16495 bd18d2873bbaab91a25aa3affab122f7 385 PIRSF PIRSF009283 12 385 4.4E-136 T 23-04-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 DC74_RS16495 bd18d2873bbaab91a25aa3affab122f7 385 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 198 339 3.4E-16 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS16495 bd18d2873bbaab91a25aa3affab122f7 385 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 26 140 1.2E-4 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS16495 bd18d2873bbaab91a25aa3affab122f7 385 PANTHER PTHR11959 6 385 3.2E-171 T 23-04-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 DC74_RS16495 bd18d2873bbaab91a25aa3affab122f7 385 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 26 385 4.5E-134 T 23-04-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 DC74_RS16495 bd18d2873bbaab91a25aa3affab122f7 385 Gene3D G3DSA:3.10.180.10 19 191 6.1E-45 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS16495 bd18d2873bbaab91a25aa3affab122f7 385 SUPERFAMILY SSF54593 19 372 1.05E-93 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS16495 bd18d2873bbaab91a25aa3affab122f7 385 Gene3D G3DSA:3.10.180.10 192 385 1.5E-80 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS35060 bc5ff50dfaf4f5422369a6692f9eeb9f 283 Gene3D G3DSA:3.40.1090.10 6 194 3.1E-5 T 23-04-2016 DC74_RS35060 bc5ff50dfaf4f5422369a6692f9eeb9f 283 Pfam PF01734 Patatin-like phospholipase 8 200 6.7E-20 T 23-04-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 DC74_RS35060 bc5ff50dfaf4f5422369a6692f9eeb9f 283 PANTHER PTHR14226 5 209 8.8E-22 T 23-04-2016 DC74_RS35060 bc5ff50dfaf4f5422369a6692f9eeb9f 283 SUPERFAMILY SSF52151 137 221 2.88E-32 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS35060 bc5ff50dfaf4f5422369a6692f9eeb9f 283 SUPERFAMILY SSF52151 1 94 2.88E-32 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS33240 c253969cae7c540dfe65d5f3a18ba361 341 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 319 1.0E-161 T 23-04-2016 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH DC74_RS33240 c253969cae7c540dfe65d5f3a18ba361 341 Pfam PF13394 4Fe-4S single cluster domain 38 113 7.7E-5 T 23-04-2016 DC74_RS33240 c253969cae7c540dfe65d5f3a18ba361 341 PANTHER PTHR11228:SF22 20 327 1.8E-102 T 23-04-2016 DC74_RS33240 c253969cae7c540dfe65d5f3a18ba361 341 Gene3D G3DSA:3.20.20.70 23 311 1.1E-40 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS33240 c253969cae7c540dfe65d5f3a18ba361 341 SUPERFAMILY SSF102114 24 309 4.32E-48 T 23-04-2016 DC74_RS33240 c253969cae7c540dfe65d5f3a18ba361 341 Pfam PF11946 Domain of unknown function (DUF3463) 197 329 3.5E-56 T 23-04-2016 IPR022563 Domain of unknown function DUF3463 DC74_RS33240 c253969cae7c540dfe65d5f3a18ba361 341 Pfam PF04055 Radical SAM superfamily 35 188 2.2E-17 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS33240 c253969cae7c540dfe65d5f3a18ba361 341 PANTHER PTHR11228 20 327 1.8E-102 T 23-04-2016 DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 4.9E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 4.9E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 4.9E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 PANTHER PTHR24322 148 179 1.6E-52 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 PANTHER PTHR24322 7 132 1.6E-52 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 SUPERFAMILY SSF51735 3 237 2.1E-63 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 3.5E-26 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 3.5E-26 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.5E-26 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.5E-26 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.5E-26 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 Pfam PF00106 short chain dehydrogenase 5 187 7.6E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02565 13d90e771521ef9762e400af0a39ac44 277 Gene3D G3DSA:3.40.50.720 2 244 2.3E-66 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS24920 846677af19d2b700987558d5f3fa3674 345 PANTHER PTHR34296 39 345 5.4E-105 T 23-04-2016 DC74_RS24920 846677af19d2b700987558d5f3fa3674 345 Gene3D G3DSA:3.40.50.2300 159 312 1.0E-47 T 23-04-2016 DC74_RS24920 846677af19d2b700987558d5f3fa3674 345 Pfam PF02608 Basic membrane protein 43 341 2.0E-63 T 23-04-2016 IPR003760 Basic membrane lipoprotein GO:0005886 DC74_RS24920 846677af19d2b700987558d5f3fa3674 345 Gene3D G3DSA:3.40.50.2300 36 158 4.3E-44 T 23-04-2016 DC74_RS24920 846677af19d2b700987558d5f3fa3674 345 SUPERFAMILY SSF53822 50 258 2.83E-12 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS24920 846677af19d2b700987558d5f3fa3674 345 PANTHER PTHR34296:SF2 39 345 5.4E-105 T 23-04-2016 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 Pfam PF02772 S-adenosylmethionine synthetase, central domain 125 248 1.6E-44 T 23-04-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 PANTHER PTHR11964 5 395 2.5E-244 T 23-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 400 56.626 T 23-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 SUPERFAMILY SSF55973 3 109 1.14E-42 T 23-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 276 284 - T 23-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 PIRSF PIRSF000497 1 401 2.3E-163 T 23-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 250 389 4.0E-67 T 23-04-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 Gene3D G3DSA:3.30.300.10 11 145 1.6E-42 T 23-04-2016 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 SUPERFAMILY SSF55973 250 399 6.67E-68 T 23-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 1.9E-38 T 23-04-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 Gene3D G3DSA:3.30.300.10 146 250 6.8E-39 T 23-04-2016 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 399 2.9E-168 T 23-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 23-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 SUPERFAMILY SSF55973 120 248 7.85E-45 T 23-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 DC74_RS37265 c9e6c1d347eac59e218dbcf3164c80a2 404 Gene3D G3DSA:3.30.300.10 261 400 6.9E-69 T 23-04-2016 DC74_RS12580 d0fa48412c3f0803c8248e13d8cf504a 319 SUPERFAMILY SSF53335 7 117 7.58E-40 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS12580 d0fa48412c3f0803c8248e13d8cf504a 319 SUPERFAMILY SSF53335 219 314 7.58E-40 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS12580 d0fa48412c3f0803c8248e13d8cf504a 319 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 313 1.4E-91 T 23-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS12580 d0fa48412c3f0803c8248e13d8cf504a 319 PIRSF PIRSF004486 1 315 5.8E-98 T 23-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS12580 d0fa48412c3f0803c8248e13d8cf504a 319 Gene3D G3DSA:1.10.150.170 117 221 2.0E-35 T 23-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS12580 d0fa48412c3f0803c8248e13d8cf504a 319 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 314 36.274 T 23-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS12580 d0fa48412c3f0803c8248e13d8cf504a 319 PANTHER PTHR11265 1 316 1.4E-134 T 23-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS12580 d0fa48412c3f0803c8248e13d8cf504a 319 SUPERFAMILY SSF81799 118 219 2.49E-32 T 23-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS12580 d0fa48412c3f0803c8248e13d8cf504a 319 Gene3D G3DSA:3.40.50.150 222 316 3.4E-48 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS12580 d0fa48412c3f0803c8248e13d8cf504a 319 Gene3D G3DSA:3.40.50.150 7 114 3.4E-48 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS12580 d0fa48412c3f0803c8248e13d8cf504a 319 Pfam PF01795 MraW methylase family 5 313 2.5E-110 T 23-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS12580 d0fa48412c3f0803c8248e13d8cf504a 319 PANTHER PTHR11265:SF0 1 316 1.4E-134 T 23-04-2016 DC74_RS10405 2393eea2b83bbec061bfe8efa294c1bf 365 PANTHER PTHR30137:SF8 1 353 9.8E-82 T 23-04-2016 DC74_RS10405 2393eea2b83bbec061bfe8efa294c1bf 365 PANTHER PTHR30137 1 353 9.8E-82 T 23-04-2016 DC74_RS10405 2393eea2b83bbec061bfe8efa294c1bf 365 Pfam PF00296 Luciferase-like monooxygenase 1 307 3.4E-71 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10405 2393eea2b83bbec061bfe8efa294c1bf 365 Gene3D G3DSA:3.20.20.30 1 345 3.4E-89 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10405 2393eea2b83bbec061bfe8efa294c1bf 365 SUPERFAMILY SSF51679 1 344 3.53E-79 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 Pfam PF13537 Glutamine amidotransferase domain 48 170 4.0E-46 T 23-04-2016 IPR017932 Glutamine amidotransferase type 2 domain DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 539 1.8E-144 T 23-04-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|UniPathway: UPA00134 DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 SUPERFAMILY SSF56235 1 225 3.43E-63 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 Gene3D G3DSA:3.60.20.10 1 224 8.2E-74 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 PANTHER PTHR11772 445 544 1.1E-194 T 23-04-2016 DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 PANTHER PTHR11772 2 399 1.1E-194 T 23-04-2016 DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 Gene3D G3DSA:3.40.50.620 463 582 9.3E-73 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 Gene3D G3DSA:3.40.50.620 225 401 9.3E-73 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 PANTHER PTHR11772:SF7 445 544 1.1E-194 T 23-04-2016 DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 PANTHER PTHR11772:SF7 2 399 1.1E-194 T 23-04-2016 DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 SUPERFAMILY SSF52402 459 583 1.89E-60 T 23-04-2016 DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 SUPERFAMILY SSF52402 230 397 1.89E-60 T 23-04-2016 DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 Pfam PF00733 Asparagine synthase 241 604 1.1E-80 T 23-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 DC74_RS37845 9d0601754c771d7cb31b9524a97ff2c3 614 PIRSF PIRSF001589 1 611 1.1E-135 T 23-04-2016 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 SUPERFAMILY SSF52151 199 290 2.38E-47 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 SUPERFAMILY SSF52151 7 137 2.38E-47 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 Gene3D G3DSA:3.30.70.250 451 517 5.8E-14 T 23-04-2016 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 SUPERFAMILY SSF55048 135 197 2.22E-5 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 337 1013 5.7E-22 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 10 303 1.0E-41 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 Gene3D G3DSA:3.40.366.10 7 131 1.3E-52 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 Gene3D G3DSA:3.40.366.10 197 295 1.3E-52 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 SUPERFAMILY SSF55048 452 518 1.44E-12 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 335 614 5.0E-88 T 23-04-2016 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 Pfam PF00698 Acyl transferase domain 8 288 5.1E-36 T 23-04-2016 IPR014043 Acyl transferase DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 Pfam PF00698 Acyl transferase domain 334 608 6.5E-28 T 23-04-2016 IPR014043 Acyl transferase DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 SUPERFAMILY SSF52151 332 448 1.54E-59 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 SUPERFAMILY SSF52151 511 625 1.54E-59 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 Gene3D G3DSA:3.40.366.10 518 621 2.9E-58 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 Gene3D G3DSA:3.40.366.10 332 448 2.9E-58 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS27035 37f1e5bd26ae76944349488918ca46bf 1109 PANTHER PTHR10982 337 611 1.8E-95 T 23-04-2016 DC74_RS37365 38ab29732661724bab2798a4342135f6 185 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 17 183 29.736 T 23-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 DC74_RS37365 38ab29732661724bab2798a4342135f6 185 Pfam PF00156 Phosphoribosyl transferase domain 46 161 3.4E-13 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 DC74_RS37365 38ab29732661724bab2798a4342135f6 185 Gene3D G3DSA:3.40.50.2020 17 182 8.9E-54 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS37365 38ab29732661724bab2798a4342135f6 185 SUPERFAMILY SSF53271 18 174 3.41E-39 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS37365 38ab29732661724bab2798a4342135f6 185 PANTHER PTHR32315 2 185 1.2E-58 T 23-04-2016 DC74_RS03580 4473baa307880900911cce4934c026dd 464 SMART SM00631 124 444 7.1E-45 T 23-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 DC74_RS03580 4473baa307880900911cce4934c026dd 464 Gene3D G3DSA:3.40.630.10 120 453 2.2E-69 T 23-04-2016 DC74_RS03580 4473baa307880900911cce4934c026dd 464 SUPERFAMILY SSF53187 121 431 4.96E-64 T 23-04-2016 DC74_RS03580 4473baa307880900911cce4934c026dd 464 Pfam PF00246 Zinc carboxypeptidase 131 425 8.0E-48 T 23-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 DC74_RS03580 4473baa307880900911cce4934c026dd 464 PANTHER PTHR11705 124 325 3.2E-57 T 23-04-2016 DC74_RS03580 4473baa307880900911cce4934c026dd 464 PANTHER PTHR11705 341 422 3.2E-57 T 23-04-2016 DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 SUPERFAMILY SSF102114 181 414 3.14E-42 T 23-04-2016 DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 190 484 5.3E-79 T 23-04-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 PANTHER PTHR11918:SF57 1 134 1.7E-183 T 23-04-2016 DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 PANTHER PTHR11918:SF57 154 489 1.7E-183 T 23-04-2016 DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 5 487 60.284 T 23-04-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 SMART SM00729 192 410 5.5E-38 T 23-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 7 484 1.7E-118 T 23-04-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 Pfam PF00919 Uncharacterized protein family UPF0004 7 105 2.8E-31 T 23-04-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 196 216 - T 23-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 Gene3D G3DSA:2.40.50.140 425 488 2.0E-16 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 PANTHER PTHR11918 1 134 1.7E-183 T 23-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 PANTHER PTHR11918 154 489 1.7E-183 T 23-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 Pfam PF04055 Radical SAM superfamily 198 368 1.4E-17 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS28670 4970e7e9f0d7258a79e74066996ef10d 501 Gene3D G3DSA:3.80.30.20 192 420 2.2E-58 T 23-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe DC74_RS10005 8bb265b2ea70142eb058f97260680a89 422 PANTHER PTHR31299 22 417 1.4E-61 T 23-04-2016 DC74_RS10005 8bb265b2ea70142eb058f97260680a89 422 Gene3D G3DSA:3.40.1660.10 3 66 7.1E-48 T 23-04-2016 DC74_RS10005 8bb265b2ea70142eb058f97260680a89 422 Gene3D G3DSA:3.40.1660.10 276 416 7.1E-48 T 23-04-2016 DC74_RS10005 8bb265b2ea70142eb058f97260680a89 422 SUPERFAMILY SSF159501 4 416 2.28E-89 T 23-04-2016 DC74_RS10005 8bb265b2ea70142eb058f97260680a89 422 Gene3D G3DSA:3.30.1870.10 67 141 1.6E-21 T 23-04-2016 DC74_RS10005 8bb265b2ea70142eb058f97260680a89 422 Pfam PF05139 Erythromycin esterase 65 410 1.1E-69 T 23-04-2016 IPR007815 Erythromycin esterase GO:0046677 DC74_RS10005 8bb265b2ea70142eb058f97260680a89 422 PIRSF PIRSF036794 2 419 4.8E-68 T 23-04-2016 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type DC74_RS10005 8bb265b2ea70142eb058f97260680a89 422 PANTHER PTHR31299:SF0 22 417 1.4E-61 T 23-04-2016 DC74_RS01485 104e29e83f24a5f8bfd1be87382a45b9 253 PANTHER PTHR13903 8 247 1.6E-80 T 23-04-2016 IPR012093 Pirin DC74_RS01485 104e29e83f24a5f8bfd1be87382a45b9 253 SUPERFAMILY SSF51182 7 246 1.09E-56 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS01485 104e29e83f24a5f8bfd1be87382a45b9 253 Gene3D G3DSA:2.60.120.10 7 247 5.0E-59 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS01485 104e29e83f24a5f8bfd1be87382a45b9 253 PIRSF PIRSF006232 3 250 1.2E-45 T 23-04-2016 IPR012093 Pirin DC74_RS01485 104e29e83f24a5f8bfd1be87382a45b9 253 PANTHER PTHR13903:SF7 8 247 1.6E-80 T 23-04-2016 DC74_RS01485 104e29e83f24a5f8bfd1be87382a45b9 253 Pfam PF02678 Pirin 14 130 6.7E-32 T 23-04-2016 IPR003829 Pirin, N-terminal domain DC74_RS22535 3b606ba6e6b81f891391c839ada2dc57 231 Pfam PF07335 Fungal chitosanase of glycosyl hydrolase group 75 85 214 2.3E-23 T 23-04-2016 IPR009939 Fungal chitosanase KEGG: 00520+3.2.1.132 DC74_RS22535 3b606ba6e6b81f891391c839ada2dc57 231 PANTHER PTHR42061 40 224 2.2E-49 T 23-04-2016 DC74_RS22535 3b606ba6e6b81f891391c839ada2dc57 231 PANTHER PTHR42061:SF1 40 224 2.2E-49 T 23-04-2016 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 PANTHER PTHR11596 293 451 2.2E-105 T 23-04-2016 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 PANTHER PTHR11596 30 273 2.2E-105 T 23-04-2016 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 Gene3D G3DSA:3.40.720.10 15 451 1.0E-121 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 PANTHER PTHR11596:SF5 293 451 2.2E-105 T 23-04-2016 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 PANTHER PTHR11596:SF5 30 273 2.2E-105 T 23-04-2016 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 SMART SM00098 48 452 2.9E-154 T 23-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 SUPERFAMILY SSF53649 21 451 1.31E-116 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 PRINTS PR00113 Alkaline phosphatase signature 140 160 1.2E-34 T 23-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 PRINTS PR00113 Alkaline phosphatase signature 102 117 1.2E-34 T 23-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 PRINTS PR00113 Alkaline phosphatase signature 202 212 1.2E-34 T 23-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 PRINTS PR00113 Alkaline phosphatase signature 300 329 1.2E-34 T 23-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 PRINTS PR00113 Alkaline phosphatase signature 47 67 1.2E-34 T 23-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 DC74_RS38200 67a86a0af7514597c5a2fd3636f97717 452 Pfam PF00245 Alkaline phosphatase 47 405 6.8E-105 T 23-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 DC74_RS09450 88edd392bf5b4473732b340ba5f1ac46 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 424 8.3E-129 T 23-04-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09450 88edd392bf5b4473732b340ba5f1ac46 428 SUPERFAMILY SSF51338 367 427 3.29E-20 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS09450 88edd392bf5b4473732b340ba5f1ac46 428 SUPERFAMILY SSF51338 1 50 3.29E-20 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS09450 88edd392bf5b4473732b340ba5f1ac46 428 SUPERFAMILY SSF51556 51 365 6.54E-102 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS09450 88edd392bf5b4473732b340ba5f1ac46 428 Gene3D G3DSA:2.30.40.10 3 65 1.0E-19 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS09450 88edd392bf5b4473732b340ba5f1ac46 428 Gene3D G3DSA:3.20.20.140 66 407 8.2E-106 T 23-04-2016 DC74_RS09450 88edd392bf5b4473732b340ba5f1ac46 428 PANTHER PTHR11647:SF70 1 427 8.7E-184 T 23-04-2016 DC74_RS09450 88edd392bf5b4473732b340ba5f1ac46 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 425 43.439 T 23-04-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09450 88edd392bf5b4473732b340ba5f1ac46 428 PANTHER PTHR11647 1 427 8.7E-184 T 23-04-2016 DC74_RS09450 88edd392bf5b4473732b340ba5f1ac46 428 Pfam PF01979 Amidohydrolase family 47 419 1.5E-18 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS09450 88edd392bf5b4473732b340ba5f1ac46 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 23-04-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS15435 9d9de4f2c3157846d20a11fd6cb992e1 381 TIGRFAM TIGR02961 allantoicase: allantoicase 39 362 5.8E-118 T 23-04-2016 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 DC74_RS15435 9d9de4f2c3157846d20a11fd6cb992e1 381 PANTHER PTHR12045 15 375 3.5E-121 T 23-04-2016 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 DC74_RS15435 9d9de4f2c3157846d20a11fd6cb992e1 381 Hamap MF_00813 Probable allantoicase [alc]. 28 365 46.146 T 23-04-2016 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 DC74_RS15435 9d9de4f2c3157846d20a11fd6cb992e1 381 Gene3D G3DSA:2.60.120.260 35 211 6.8E-57 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS15435 9d9de4f2c3157846d20a11fd6cb992e1 381 Gene3D G3DSA:2.60.120.260 217 366 5.8E-40 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS15435 9d9de4f2c3157846d20a11fd6cb992e1 381 PIRSF PIRSF016516 28 366 1.0E-91 T 23-04-2016 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 DC74_RS15435 9d9de4f2c3157846d20a11fd6cb992e1 381 Pfam PF03561 Allantoicase repeat 48 207 2.6E-45 T 23-04-2016 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 DC74_RS15435 9d9de4f2c3157846d20a11fd6cb992e1 381 Pfam PF03561 Allantoicase repeat 230 362 9.8E-38 T 23-04-2016 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 DC74_RS15435 9d9de4f2c3157846d20a11fd6cb992e1 381 SUPERFAMILY SSF49785 34 211 1.79E-52 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS15435 9d9de4f2c3157846d20a11fd6cb992e1 381 SUPERFAMILY SSF49785 215 364 1.68E-40 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 2 888 0.0 T 23-04-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 Gene3D G3DSA:3.30.1490.20 2 108 3.7E-57 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 Gene3D G3DSA:3.30.1490.20 197 240 3.7E-57 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 SUPERFAMILY SSF56059 2 374 4.94E-134 T 23-04-2016 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 PANTHER PTHR22931 2 644 0.0 T 23-04-2016 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 Gene3D G3DSA:3.50.30.10 396 503 2.4E-38 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 Gene3D G3DSA:3.30.470.20 241 338 5.5E-34 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 533 885 1.3E-86 T 23-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 PANTHER PTHR22931:SF9 2 644 0.0 T 23-04-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 PANTHER PTHR22931:SF9 661 897 0.0 T 23-04-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 Gene3D G3DSA:1.10.189.10 339 395 5.7E-23 T 23-04-2016 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 Gene3D G3DSA:1.20.80.30 109 195 1.2E-34 T 23-04-2016 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 Gene3D G3DSA:3.20.20.60 546 890 2.3E-128 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 Pfam PF00391 PEP-utilising enzyme, mobile domain 417 499 1.9E-25 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 SUPERFAMILY SSF52009 380 508 8.37E-35 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 SUPERFAMILY SSF51621 535 887 1.28E-113 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 16 284 6.1E-42 T 23-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 292 348 1.4E-9 T 23-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 PIRSF PIRSF000853 1 897 0.0 T 23-04-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 PANTHER PTHR22931 661 897 0.0 T 23-04-2016 DC74_RS14795 6f05e658cd294f78c8c0e9948bf7352d 897 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 445 456 - T 23-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 DC74_RS20025 50e0fb7c1349b986ccc5a5a2bd6b322e 256 SUPERFAMILY SSF49899 70 251 1.19E-30 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS20025 50e0fb7c1349b986ccc5a5a2bd6b322e 256 Gene3D G3DSA:2.60.120.200 55 250 1.2E-31 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS20025 50e0fb7c1349b986ccc5a5a2bd6b322e 256 SMART SM00560 110 245 2.3E-7 T 23-04-2016 IPR006558 LamG-like jellyroll fold DC74_RS20025 50e0fb7c1349b986ccc5a5a2bd6b322e 256 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 94 247 1.4E-25 T 23-04-2016 DC74_RS00930 062b1c9261ba9aba855feb3954ffe0a7 164 Gene3D G3DSA:1.10.357.10 4 149 2.0E-21 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS00930 062b1c9261ba9aba855feb3954ffe0a7 164 Pfam PF00440 Bacterial regulatory proteins, tetR family 4 42 1.1E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00930 062b1c9261ba9aba855feb3954ffe0a7 164 SUPERFAMILY SSF46689 3 64 1.03E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00930 062b1c9261ba9aba855feb3954ffe0a7 164 PANTHER PTHR30055 1 118 2.8E-26 T 23-04-2016 DC74_RS00930 062b1c9261ba9aba855feb3954ffe0a7 164 PANTHER PTHR30055:SF18 1 118 2.8E-26 T 23-04-2016 DC74_RS01725 594e0503c6365ef6a21114e749a97957 150 Gene3D G3DSA:1.10.287.100 106 148 1.3E-9 T 23-04-2016 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 DC74_RS01725 594e0503c6365ef6a21114e749a97957 150 Pfam PF12802 MarR family 39 97 8.2E-10 T 23-04-2016 DC74_RS01725 594e0503c6365ef6a21114e749a97957 150 Gene3D G3DSA:1.10.10.10 39 103 3.5E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01725 594e0503c6365ef6a21114e749a97957 150 SMART SM00347 33 133 3.5E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS01725 594e0503c6365ef6a21114e749a97957 150 PANTHER PTHR33164 19 149 2.8E-28 T 23-04-2016 DC74_RS01725 594e0503c6365ef6a21114e749a97957 150 PANTHER PTHR33164:SF2 19 149 2.8E-28 T 23-04-2016 DC74_RS01725 594e0503c6365ef6a21114e749a97957 150 SUPERFAMILY SSF46785 20 144 1.53E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18725 b1e333506931f1bf70cca538881cf0fa 107 Gene3D G3DSA:3.30.70.330 13 103 1.2E-36 T 23-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 DC74_RS18725 b1e333506931f1bf70cca538881cf0fa 107 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 15 104 22.244 T 23-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 DC74_RS18725 b1e333506931f1bf70cca538881cf0fa 107 PANTHER PTHR11620 13 102 4.9E-35 T 23-04-2016 DC74_RS18725 b1e333506931f1bf70cca538881cf0fa 107 ProSitePatterns PS00050 Ribosomal protein L23 signature. 87 102 - T 23-04-2016 IPR001014 Ribosomal protein L23/L25, conserved site DC74_RS18725 b1e333506931f1bf70cca538881cf0fa 107 SUPERFAMILY SSF54189 12 104 7.55E-33 T 23-04-2016 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18725 b1e333506931f1bf70cca538881cf0fa 107 Pfam PF00276 Ribosomal protein L23 16 101 2.1E-32 T 23-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 DC74_RS19040 64c4ece471fdb25b56f9efa118969e1a 459 PANTHER PTHR11432 25 367 1.1E-159 T 23-04-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 DC74_RS19040 64c4ece471fdb25b56f9efa118969e1a 459 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 238 251 - T 23-04-2016 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 DC74_RS19040 64c4ece471fdb25b56f9efa118969e1a 459 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 71 86 - T 23-04-2016 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 DC74_RS19040 64c4ece471fdb25b56f9efa118969e1a 459 PANTHER PTHR11432:SF3 25 367 1.1E-159 T 23-04-2016 DC74_RS19040 64c4ece471fdb25b56f9efa118969e1a 459 Pfam PF00146 NADH dehydrogenase 32 355 1.2E-123 T 23-04-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 DC74_RS19040 64c4ece471fdb25b56f9efa118969e1a 459 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 25 362 24.321 T 23-04-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 DC74_RS31920 81b08fea0cf6b8188eeaed41302f175e 271 Gene3D G3DSA:3.40.50.150 7 265 2.2E-46 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS31920 81b08fea0cf6b8188eeaed41302f175e 271 PANTHER PTHR10108:SF815 31 250 5.1E-87 T 23-04-2016 DC74_RS31920 81b08fea0cf6b8188eeaed41302f175e 271 PANTHER PTHR10108 31 250 5.1E-87 T 23-04-2016 DC74_RS31920 81b08fea0cf6b8188eeaed41302f175e 271 SUPERFAMILY SSF53335 6 258 1.43E-44 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS31920 81b08fea0cf6b8188eeaed41302f175e 271 Pfam PF13847 Methyltransferase domain 38 153 3.1E-26 T 23-04-2016 IPR025714 Methyltransferase domain DC74_RS37780 93b051e4957618fec31ef20302006049 300 PANTHER PTHR31964:SF42 1 159 1.8E-21 T 23-04-2016 DC74_RS37780 93b051e4957618fec31ef20302006049 300 SUPERFAMILY SSF52402 4 138 1.84E-19 T 23-04-2016 DC74_RS37780 93b051e4957618fec31ef20302006049 300 PANTHER PTHR31964 1 159 1.8E-21 T 23-04-2016 DC74_RS37780 93b051e4957618fec31ef20302006049 300 PRINTS PR01438 Universal stress protein signature 97 109 4.6E-5 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS37780 93b051e4957618fec31ef20302006049 300 PRINTS PR01438 Universal stress protein signature 115 137 4.6E-5 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS37780 93b051e4957618fec31ef20302006049 300 Gene3D G3DSA:3.40.50.620 2 137 8.8E-24 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS37780 93b051e4957618fec31ef20302006049 300 Gene3D G3DSA:3.40.50.620 164 300 7.4E-18 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS37780 93b051e4957618fec31ef20302006049 300 Pfam PF00582 Universal stress protein family 5 137 2.4E-17 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS37780 93b051e4957618fec31ef20302006049 300 Pfam PF00582 Universal stress protein family 164 300 5.4E-11 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS37780 93b051e4957618fec31ef20302006049 300 SUPERFAMILY SSF52402 164 300 6.78E-18 T 23-04-2016 DC74_RS25750 41ff0340bca03180ee478ef7c06a3470 559 Pfam PF13520 Amino acid permease 21 429 9.4E-47 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS25750 41ff0340bca03180ee478ef7c06a3470 559 PANTHER PTHR11785 18 462 4.1E-126 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS25750 41ff0340bca03180ee478ef7c06a3470 559 PIRSF PIRSF006060 2 471 6.1E-73 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS25750 41ff0340bca03180ee478ef7c06a3470 559 PANTHER PTHR11785:SF322 18 462 4.1E-126 T 23-04-2016 DC74_RS28710 79662254155899d4f36151cbfe6f2c68 311 Gene3D G3DSA:1.10.10.60 183 237 1.6E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS28710 79662254155899d4f36151cbfe6f2c68 311 Gene3D G3DSA:2.60.120.280 40 166 8.3E-16 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS28710 79662254155899d4f36151cbfe6f2c68 311 SUPERFAMILY SSF46689 185 233 8.24E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS28710 79662254155899d4f36151cbfe6f2c68 311 Pfam PF02311 AraC-like ligand binding domain 29 158 3.3E-25 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS28710 79662254155899d4f36151cbfe6f2c68 311 PANTHER PTHR11019:SF75 16 289 6.3E-71 T 23-04-2016 DC74_RS28710 79662254155899d4f36151cbfe6f2c68 311 PANTHER PTHR11019 16 289 6.3E-71 T 23-04-2016 DC74_RS28710 79662254155899d4f36151cbfe6f2c68 311 Pfam PF12833 Helix-turn-helix domain 205 282 3.3E-20 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS28710 79662254155899d4f36151cbfe6f2c68 311 SMART SM00342 199 281 6.4E-27 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS28710 79662254155899d4f36151cbfe6f2c68 311 SUPERFAMILY SSF46689 236 283 1.47E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS28710 79662254155899d4f36151cbfe6f2c68 311 SUPERFAMILY SSF51215 40 166 1.57E-20 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS28710 79662254155899d4f36151cbfe6f2c68 311 Gene3D G3DSA:1.10.10.60 238 283 1.5E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS33560 9d1844a86dc2a6d10d7921324cde69b4 520 Gene3D G3DSA:2.30.38.10 331 408 2.7E-11 T 23-04-2016 DC74_RS33560 9d1844a86dc2a6d10d7921324cde69b4 520 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS33560 9d1844a86dc2a6d10d7921324cde69b4 520 Gene3D G3DSA:3.40.50.980 8 170 7.9E-27 T 23-04-2016 DC74_RS33560 9d1844a86dc2a6d10d7921324cde69b4 520 Gene3D G3DSA:3.40.50.980 171 330 7.2E-36 T 23-04-2016 DC74_RS33560 9d1844a86dc2a6d10d7921324cde69b4 520 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 502 1.1E-14 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS33560 9d1844a86dc2a6d10d7921324cde69b4 520 PANTHER PTHR24096 18 514 1.0E-160 T 23-04-2016 DC74_RS33560 9d1844a86dc2a6d10d7921324cde69b4 520 Pfam PF00501 AMP-binding enzyme 7 418 1.9E-64 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS33560 9d1844a86dc2a6d10d7921324cde69b4 520 SUPERFAMILY SSF56801 9 515 5.1E-121 T 23-04-2016 DC74_RS33560 9d1844a86dc2a6d10d7921324cde69b4 520 PANTHER PTHR24096:SF106 18 514 1.0E-160 T 23-04-2016 DC74_RS33560 9d1844a86dc2a6d10d7921324cde69b4 520 Gene3D G3DSA:3.30.300.30 414 513 3.1E-29 T 23-04-2016 DC74_RS03430 ace9d3568e141fb11d39377a62f1be32 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 76 2.1E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03430 ace9d3568e141fb11d39377a62f1be32 226 PANTHER PTHR30055:SF43 13 224 4.7E-42 T 23-04-2016 DC74_RS03430 ace9d3568e141fb11d39377a62f1be32 226 SUPERFAMILY SSF48498 96 201 2.8E-19 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS03430 ace9d3568e141fb11d39377a62f1be32 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 2.0E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03430 ace9d3568e141fb11d39377a62f1be32 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 2.0E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03430 ace9d3568e141fb11d39377a62f1be32 226 PANTHER PTHR30055 13 224 4.7E-42 T 23-04-2016 DC74_RS03430 ace9d3568e141fb11d39377a62f1be32 226 Gene3D G3DSA:1.10.357.10 21 210 7.3E-39 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS03430 ace9d3568e141fb11d39377a62f1be32 226 SUPERFAMILY SSF46689 20 100 1.46E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS12510 c74e50a80ba6783ac2055f996c4e00c7 97 Pfam PF02325 YGGT family 10 90 4.0E-12 T 23-04-2016 IPR003425 CCB3/YggT GO:0016020 DC74_RS33760 e557be10f1b54fa8de675ab8d6a33b93 380 PANTHER PTHR10909 10 372 3.5E-93 T 23-04-2016 DC74_RS33760 e557be10f1b54fa8de675ab8d6a33b93 380 Gene3D G3DSA:1.20.140.10 236 372 2.8E-33 T 23-04-2016 DC74_RS33760 e557be10f1b54fa8de675ab8d6a33b93 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 371 8.6E-27 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS33760 e557be10f1b54fa8de675ab8d6a33b93 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 100 8.5E-15 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS33760 e557be10f1b54fa8de675ab8d6a33b93 380 SUPERFAMILY SSF56645 13 217 1.31E-25 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS33760 e557be10f1b54fa8de675ab8d6a33b93 380 PANTHER PTHR10909:SF302 10 372 3.5E-93 T 23-04-2016 DC74_RS33760 e557be10f1b54fa8de675ab8d6a33b93 380 Gene3D G3DSA:1.10.540.10 6 108 1.6E-17 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS33760 e557be10f1b54fa8de675ab8d6a33b93 380 SUPERFAMILY SSF47203 235 373 8.22E-34 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 Gene3D G3DSA:2.40.40.20 492 564 3.7E-38 T 23-04-2016 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 Gene3D G3DSA:2.40.40.20 424 451 3.7E-38 T 23-04-2016 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1251 0.0 T 23-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1260 10.004 T 23-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 SUPERFAMILY SSF64484 5 1251 0.0 T 23-04-2016 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 PANTHER PTHR19376 213 628 0.0 T 23-04-2016 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 PANTHER PTHR19376 659 1146 0.0 T 23-04-2016 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 4.4E-82 T 23-04-2016 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 PANTHER PTHR19376 2 157 0.0 T 23-04-2016 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 PANTHER PTHR19376 1187 1278 0.0 T 23-04-2016 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 PANTHER PTHR19376:SF32 213 628 0.0 T 23-04-2016 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 PANTHER PTHR19376:SF32 2 157 0.0 T 23-04-2016 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 PANTHER PTHR19376:SF32 659 1146 0.0 T 23-04-2016 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 PANTHER PTHR19376:SF32 1187 1278 0.0 T 23-04-2016 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 Gene3D G3DSA:2.40.50.100 1041 1095 2.8E-10 T 23-04-2016 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 Pfam PF00623 RNA polymerase Rpb1, domain 2 468 560 9.6E-28 T 23-04-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 480 1.3E-8 T 23-04-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 731 1.9E-21 T 23-04-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 Pfam PF04998 RNA polymerase Rpb1, domain 5 838 1199 2.7E-66 T 23-04-2016 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 Pfam PF05000 RNA polymerase Rpb1, domain 4 760 824 4.3E-14 T 23-04-2016 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18770 303eee9fc2c9aeef151cb0fb0d564539 1299 SMART SM00663 310 589 2.9E-174 T 23-04-2016 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS18140 6461e6e0f29d1ad63f23e056f08e6342 373 Pfam PF03747 ADP-ribosylglycohydrolase 25 327 9.5E-70 T 23-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 DC74_RS18140 6461e6e0f29d1ad63f23e056f08e6342 373 PANTHER PTHR16222 8 371 8.0E-94 T 23-04-2016 DC74_RS18140 6461e6e0f29d1ad63f23e056f08e6342 373 SUPERFAMILY SSF101478 18 348 1.44E-67 T 23-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 DC74_RS18140 6461e6e0f29d1ad63f23e056f08e6342 373 PANTHER PTHR16222:SF12 8 371 8.0E-94 T 23-04-2016 DC74_RS29060 973e76cd48639f1aeab8ddde6e35d139 460 Gene3D G3DSA:3.30.830.10 247 440 2.6E-10 T 23-04-2016 IPR011237 Peptidase M16 domain GO:0046872 DC74_RS29060 973e76cd48639f1aeab8ddde6e35d139 460 SUPERFAMILY SSF63411 14 224 1.47E-37 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 DC74_RS29060 973e76cd48639f1aeab8ddde6e35d139 460 Pfam PF05193 Peptidase M16 inactive domain 185 373 8.9E-19 T 23-04-2016 IPR007863 Peptidase M16, C-terminal DC74_RS29060 973e76cd48639f1aeab8ddde6e35d139 460 Gene3D G3DSA:3.30.830.10 22 227 3.3E-32 T 23-04-2016 IPR011237 Peptidase M16 domain GO:0046872 DC74_RS29060 973e76cd48639f1aeab8ddde6e35d139 460 PANTHER PTHR11851:SF144 6 442 2.1E-65 T 23-04-2016 DC74_RS29060 973e76cd48639f1aeab8ddde6e35d139 460 PANTHER PTHR11851 6 442 2.1E-65 T 23-04-2016 DC74_RS29060 973e76cd48639f1aeab8ddde6e35d139 460 Pfam PF00675 Insulinase (Peptidase family M16) 32 159 3.3E-11 T 23-04-2016 IPR011765 Peptidase M16, N-terminal DC74_RS29060 973e76cd48639f1aeab8ddde6e35d139 460 SUPERFAMILY SSF63411 237 456 3.86E-18 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 DC74_RS28290 6376c0dbe6ed24287def16130b999bb7 393 Pfam PF13416 Bacterial extracellular solute-binding protein 75 347 1.5E-28 T 23-04-2016 DC74_RS28290 6376c0dbe6ed24287def16130b999bb7 393 PANTHER PTHR30222:SF5 46 375 8.8E-86 T 23-04-2016 DC74_RS28290 6376c0dbe6ed24287def16130b999bb7 393 Gene3D G3DSA:3.40.190.10 63 180 1.9E-9 T 23-04-2016 DC74_RS28290 6376c0dbe6ed24287def16130b999bb7 393 PANTHER PTHR30222 46 375 8.8E-86 T 23-04-2016 DC74_RS28290 6376c0dbe6ed24287def16130b999bb7 393 SUPERFAMILY SSF53850 50 391 1.09E-62 T 23-04-2016 DC74_RS28290 6376c0dbe6ed24287def16130b999bb7 393 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 242 261 2.6E-12 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 DC74_RS28290 6376c0dbe6ed24287def16130b999bb7 393 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 160 176 2.6E-12 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 DC74_RS28290 6376c0dbe6ed24287def16130b999bb7 393 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 286 305 2.6E-12 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 DC74_RS28290 6376c0dbe6ed24287def16130b999bb7 393 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 112 126 2.6E-12 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 DC74_RS28290 6376c0dbe6ed24287def16130b999bb7 393 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 185 199 2.6E-12 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 DC74_RS28290 6376c0dbe6ed24287def16130b999bb7 393 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 128 141 2.6E-12 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 DC74_RS28290 6376c0dbe6ed24287def16130b999bb7 393 Gene3D G3DSA:3.40.190.10 181 335 6.0E-44 T 23-04-2016 DC74_RS23155 c2bfd384e40b3cf42d2262a0bcf0c8a7 121 SUPERFAMILY SSF75169 3 112 1.28E-20 T 23-04-2016 IPR027396 DsrEFH-like DC74_RS23155 c2bfd384e40b3cf42d2262a0bcf0c8a7 121 PANTHER PTHR33279 5 121 1.9E-47 T 23-04-2016 DC74_RS23155 c2bfd384e40b3cf42d2262a0bcf0c8a7 121 PANTHER PTHR33279:SF2 5 121 1.9E-47 T 23-04-2016 DC74_RS23155 c2bfd384e40b3cf42d2262a0bcf0c8a7 121 Gene3D G3DSA:3.40.1260.10 3 109 4.0E-19 T 23-04-2016 IPR027396 DsrEFH-like DC74_RS23155 c2bfd384e40b3cf42d2262a0bcf0c8a7 121 Pfam PF02635 DsrE/DsrF-like family 3 104 4.2E-12 T 23-04-2016 IPR003787 Sulphur relay, DsrE/F-like protein DC74_RS33355 1afc989bef5fe171285549ee16869daa 193 SMART SM00065 33 190 4.6E-5 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS33355 1afc989bef5fe171285549ee16869daa 193 Pfam PF01590 GAF domain 37 176 2.7E-13 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS33355 1afc989bef5fe171285549ee16869daa 193 SUPERFAMILY SSF55781 37 188 2.45E-22 T 23-04-2016 IPR029016 GAF domain-like DC74_RS33355 1afc989bef5fe171285549ee16869daa 193 Gene3D G3DSA:3.30.450.40 31 189 5.7E-16 T 23-04-2016 IPR029016 GAF domain-like DC74_RS33355 1afc989bef5fe171285549ee16869daa 193 PANTHER PTHR33121 86 178 5.2E-12 T 23-04-2016 DC74_RS33355 1afc989bef5fe171285549ee16869daa 193 PANTHER PTHR33121:SF12 86 178 5.2E-12 T 23-04-2016 DC74_RS38080 a8dc1ea09554bfe1e5f3ec6e461d29f9 414 Pfam PF05977 Transmembrane secretion effector 10 395 2.3E-34 T 23-04-2016 IPR010290 Transmembrane secretion effector DC74_RS38080 a8dc1ea09554bfe1e5f3ec6e461d29f9 414 Gene3D G3DSA:1.20.1250.20 29 187 4.3E-10 T 23-04-2016 DC74_RS38080 a8dc1ea09554bfe1e5f3ec6e461d29f9 414 SUPERFAMILY SSF103473 17 401 4.32E-35 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS38080 a8dc1ea09554bfe1e5f3ec6e461d29f9 414 PANTHER PTHR23513 2 405 1.1E-79 T 23-04-2016 DC74_RS38080 a8dc1ea09554bfe1e5f3ec6e461d29f9 414 PANTHER PTHR23513:SF9 2 405 1.1E-79 T 23-04-2016 DC74_RS38080 a8dc1ea09554bfe1e5f3ec6e461d29f9 414 Gene3D G3DSA:1.20.1250.20 243 396 2.0E-12 T 23-04-2016 DC74_RS08005 6cd33c1e0f22d26ce57f8227f08055e3 211 Gene3D G3DSA:1.10.357.10 8 187 3.8E-37 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS08005 6cd33c1e0f22d26ce57f8227f08055e3 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.9E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS08005 6cd33c1e0f22d26ce57f8227f08055e3 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.9E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS08005 6cd33c1e0f22d26ce57f8227f08055e3 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 3.3E-19 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS08005 6cd33c1e0f22d26ce57f8227f08055e3 211 SUPERFAMILY SSF46689 4 65 7.18E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS08005 6cd33c1e0f22d26ce57f8227f08055e3 211 SUPERFAMILY SSF48498 86 198 7.12E-12 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS08005 6cd33c1e0f22d26ce57f8227f08055e3 211 Pfam PF13977 Bacterial transcriptional repressor 96 198 1.4E-8 T 23-04-2016 DC74_RS08005 6cd33c1e0f22d26ce57f8227f08055e3 211 PANTHER PTHR30055 1 188 3.6E-28 T 23-04-2016 DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 SUPERFAMILY SSF55486 199 448 8.06E-69 T 23-04-2016 DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 4 851 0.0 T 23-04-2016 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 Pfam PF11838 ERAP1-like C-terminal domain 515 845 2.0E-47 T 23-04-2016 IPR024571 ERAP1-like C-terminal domain DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 SUPERFAMILY SSF63737 4 189 2.35E-34 T 23-04-2016 DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 306 318 4.1E-21 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 287 302 4.1E-21 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 172 187 4.1E-21 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 129 144 4.1E-21 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 253 263 4.1E-21 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 Pfam PF01433 Peptidase family M1 21 382 6.8E-60 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 PANTHER PTHR11533:SF190 20 594 2.7E-140 T 23-04-2016 DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 Gene3D G3DSA:1.10.390.10 300 450 2.9E-38 T 23-04-2016 DC74_RS12155 6431724a59e5cf8b72105e6a383f49d3 855 PANTHER PTHR11533 20 594 2.7E-140 T 23-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 DC74_RS18700 50d33a1e947dfa53150dc9a3f8b67a53 139 SUPERFAMILY SSF54686 1 135 4.84E-54 T 23-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 DC74_RS18700 50d33a1e947dfa53150dc9a3f8b67a53 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 23-04-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18700 50d33a1e947dfa53150dc9a3f8b67a53 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.3E-53 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 DC74_RS18700 50d33a1e947dfa53150dc9a3f8b67a53 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.2E-46 T 23-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 DC74_RS18700 50d33a1e947dfa53150dc9a3f8b67a53 139 PANTHER PTHR12220 1 135 7.3E-67 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 DC74_RS18700 50d33a1e947dfa53150dc9a3f8b67a53 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 23-04-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18700 50d33a1e947dfa53150dc9a3f8b67a53 139 Gene3D G3DSA:3.90.1170.10 23 136 2.3E-51 T 23-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 DC74_RS18700 50d33a1e947dfa53150dc9a3f8b67a53 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.4E-37 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 DC74_RS18700 50d33a1e947dfa53150dc9a3f8b67a53 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.4E-37 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 DC74_RS18700 50d33a1e947dfa53150dc9a3f8b67a53 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.4E-37 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 DC74_RS18700 50d33a1e947dfa53150dc9a3f8b67a53 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.4E-37 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 DC74_RS18700 50d33a1e947dfa53150dc9a3f8b67a53 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.559 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 DC74_RS23895 82fbac0f9544706a292a3ed846403bf8 366 Pfam PF00285 Citrate synthase, C-terminal domain 7 343 7.4E-87 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS23895 82fbac0f9544706a292a3ed846403bf8 366 PANTHER PTHR11739 3 366 1.7E-254 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS23895 82fbac0f9544706a292a3ed846403bf8 366 SUPERFAMILY SSF48256 3 354 1.57E-96 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS23895 82fbac0f9544706a292a3ed846403bf8 366 PRINTS PR00143 Citrate synthase signature 235 255 3.4E-26 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS23895 82fbac0f9544706a292a3ed846403bf8 366 PRINTS PR00143 Citrate synthase signature 160 175 3.4E-26 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS23895 82fbac0f9544706a292a3ed846403bf8 366 PRINTS PR00143 Citrate synthase signature 314 328 3.4E-26 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS23895 82fbac0f9544706a292a3ed846403bf8 366 PRINTS PR00143 Citrate synthase signature 182 210 3.4E-26 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS23895 82fbac0f9544706a292a3ed846403bf8 366 PRINTS PR00143 Citrate synthase signature 294 310 3.4E-26 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS23895 82fbac0f9544706a292a3ed846403bf8 366 Gene3D G3DSA:1.10.230.10 222 306 1.5E-25 T 23-04-2016 IPR016143 Citrate synthase-like, small alpha subdomain DC74_RS23895 82fbac0f9544706a292a3ed846403bf8 366 Gene3D G3DSA:1.10.580.10 13 221 3.3E-48 T 23-04-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 DC74_RS23895 82fbac0f9544706a292a3ed846403bf8 366 ProSitePatterns PS00480 Citrate synthase signature. 242 254 - T 23-04-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 DC74_RS23895 82fbac0f9544706a292a3ed846403bf8 366 PANTHER PTHR11739:SF14 3 366 1.7E-254 T 23-04-2016 DC74_RS32445 e990408e1b05ebb0b491ea524aa5a65e 453 PANTHER PTHR11712:SF282 21 393 5.7E-73 T 23-04-2016 DC74_RS32445 e990408e1b05ebb0b491ea524aa5a65e 453 SUPERFAMILY SSF48264 5 393 4.19E-61 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS32445 e990408e1b05ebb0b491ea524aa5a65e 453 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 333 342 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS32445 e990408e1b05ebb0b491ea524aa5a65e 453 PRINTS PR00359 B-class P450 signature 188 210 1.4E-23 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32445 e990408e1b05ebb0b491ea524aa5a65e 453 PRINTS PR00359 B-class P450 signature 91 102 1.4E-23 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32445 e990408e1b05ebb0b491ea524aa5a65e 453 PRINTS PR00359 B-class P450 signature 137 153 1.4E-23 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32445 e990408e1b05ebb0b491ea524aa5a65e 453 PRINTS PR00359 B-class P450 signature 331 340 1.4E-23 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32445 e990408e1b05ebb0b491ea524aa5a65e 453 PRINTS PR00359 B-class P450 signature 284 311 1.4E-23 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32445 e990408e1b05ebb0b491ea524aa5a65e 453 PRINTS PR00359 B-class P450 signature 154 169 1.4E-23 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32445 e990408e1b05ebb0b491ea524aa5a65e 453 PANTHER PTHR11712 21 393 5.7E-73 T 23-04-2016 DC74_RS32445 e990408e1b05ebb0b491ea524aa5a65e 453 Gene3D G3DSA:1.10.630.10 4 393 1.2E-88 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS05540 5fd0dfe733a452f998504d9846186809 268 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 214 5.6E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS05540 5fd0dfe733a452f998504d9846186809 268 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 230 242 5.6E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS05540 5fd0dfe733a452f998504d9846186809 268 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 214 230 5.6E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS05540 5fd0dfe733a452f998504d9846186809 268 Gene3D G3DSA:1.10.10.10 192 258 2.6E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05540 5fd0dfe733a452f998504d9846186809 268 SMART SM00421 197 254 5.9E-17 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS05540 5fd0dfe733a452f998504d9846186809 268 Pfam PF00196 Bacterial regulatory proteins, luxR family 200 252 4.4E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS05540 5fd0dfe733a452f998504d9846186809 268 SUPERFAMILY SSF46894 192 260 3.16E-16 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 1 379 7.1E-107 T 23-04-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 PANTHER PTHR11609 145 380 5.8E-129 T 23-04-2016 DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 PANTHER PTHR11609 1 125 5.8E-129 T 23-04-2016 DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 SUPERFAMILY SSF51246 321 389 1.33E-16 T 23-04-2016 IPR011054 Rudiment single hybrid motif DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 Gene3D G3DSA:3.30.470.20 168 390 4.9E-80 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 Gene3D G3DSA:3.40.50.20 2 101 6.2E-27 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 1 374 37.257 T 23-04-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 PANTHER PTHR11609:SF5 145 380 5.8E-129 T 23-04-2016 DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 PANTHER PTHR11609:SF5 1 125 5.8E-129 T 23-04-2016 DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 Gene3D G3DSA:3.30.1490.20 106 167 9.8E-9 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 SUPERFAMILY SSF52440 2 90 6.76E-24 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 Pfam PF02222 ATP-grasp domain 149 295 1.1E-45 T 23-04-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UniPathway: UPA00074 DC74_RS17145 86d7921f66ddf537267bcfb46a47dd83 394 SUPERFAMILY SSF56059 95 315 1.71E-52 T 23-04-2016 DC74_RS02385 97aa25922e5facc418873c78cca29b08 246 ProDom PD037589 AROM ARO OPERON REGULATED BY AROR BIOSYNTHESIS TRANSCRIPTION AMINO AROMATIC 16 240 3.0E-23 T 23-04-2016 IPR010843 Uncharacterised protein family AroM DC74_RS02385 97aa25922e5facc418873c78cca29b08 246 Pfam PF07302 AroM protein 16 240 1.1E-65 T 23-04-2016 IPR010843 Uncharacterised protein family AroM DC74_RS11900 395bea68911d7a3634b2d210908cf187 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 78 1.4E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS11900 395bea68911d7a3634b2d210908cf187 231 PANTHER PTHR30055:SF54 21 199 1.8E-39 T 23-04-2016 DC74_RS11900 395bea68911d7a3634b2d210908cf187 231 PANTHER PTHR30055 21 199 1.8E-39 T 23-04-2016 DC74_RS11900 395bea68911d7a3634b2d210908cf187 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 1.0E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS11900 395bea68911d7a3634b2d210908cf187 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 1.0E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS11900 395bea68911d7a3634b2d210908cf187 231 Gene3D G3DSA:1.10.357.10 76 223 3.6E-20 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS11900 395bea68911d7a3634b2d210908cf187 231 SUPERFAMILY SSF48498 99 192 2.92E-5 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS11900 395bea68911d7a3634b2d210908cf187 231 Gene3D G3DSA:1.10.10.60 23 75 3.5E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS11900 395bea68911d7a3634b2d210908cf187 231 SUPERFAMILY SSF46689 23 101 3.74E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS28465 c2d34170c86742032118e50b31a72b31 880 PANTHER PTHR13696:SF1 520 788 8.6E-49 T 23-04-2016 DC74_RS28465 c2d34170c86742032118e50b31a72b31 880 Pfam PF13614 AAA domain 541 688 5.9E-11 T 23-04-2016 IPR025669 AAA domain DC74_RS28465 c2d34170c86742032118e50b31a72b31 880 SUPERFAMILY SSF52540 539 775 2.86E-25 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28465 c2d34170c86742032118e50b31a72b31 880 Gene3D G3DSA:3.40.50.300 540 770 3.0E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28465 c2d34170c86742032118e50b31a72b31 880 PANTHER PTHR13696 520 788 8.6E-49 T 23-04-2016 DC74_RS16985 6029e91f982820446d6144993a6be597 87 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 6 86 15.859 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS16985 6029e91f982820446d6144993a6be597 87 Pfam PF02467 Transcription factor WhiB 19 82 6.1E-27 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS16985 6029e91f982820446d6144993a6be597 87 PANTHER PTHR38839:SF4 1 85 1.4E-57 T 23-04-2016 DC74_RS16985 6029e91f982820446d6144993a6be597 87 PANTHER PTHR38839 1 85 1.4E-57 T 23-04-2016 DC74_RS09230 9093af76c2f423cadcb20387b047f7fe 402 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 157 371 1.7E-56 T 23-04-2016 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 DC74_RS09230 9093af76c2f423cadcb20387b047f7fe 402 SUPERFAMILY SSF53597 156 369 1.96E-53 T 23-04-2016 IPR024072 Dihydrofolate reductase-like domain DC74_RS09230 9093af76c2f423cadcb20387b047f7fe 402 PANTHER PTHR11079 18 235 4.3E-55 T 23-04-2016 DC74_RS09230 9093af76c2f423cadcb20387b047f7fe 402 SUPERFAMILY SSF53927 16 151 5.16E-41 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS09230 9093af76c2f423cadcb20387b047f7fe 402 Gene3D G3DSA:3.40.140.10 16 138 1.1E-26 T 23-04-2016 DC74_RS09230 9093af76c2f423cadcb20387b047f7fe 402 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 62 100 - T 23-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 DC74_RS09230 9093af76c2f423cadcb20387b047f7fe 402 Gene3D G3DSA:3.40.430.10 139 370 1.1E-67 T 23-04-2016 IPR024072 Dihydrofolate reductase-like domain DC74_RS09230 9093af76c2f423cadcb20387b047f7fe 402 Pfam PF01872 RibD C-terminal domain 158 366 3.6E-49 T 23-04-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 DC74_RS09230 9093af76c2f423cadcb20387b047f7fe 402 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 16 111 7.3E-17 T 23-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 DC74_RS09230 9093af76c2f423cadcb20387b047f7fe 402 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 18 367 5.1E-109 T 23-04-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525|UniPathway: UPA00275|UniPathway: UPA00275 DC74_RS09230 9093af76c2f423cadcb20387b047f7fe 402 PANTHER PTHR11079:SF10 18 235 4.3E-55 T 23-04-2016 DC74_RS09230 9093af76c2f423cadcb20387b047f7fe 402 PIRSF PIRSF006769 10 375 4.6E-121 T 23-04-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525|UniPathway: UPA00275|UniPathway: UPA00275 DC74_RS04915 b69f5c4aa60cc41a2bf8cccde1ce48c6 562 PANTHER PTHR24222 19 512 7.7E-57 T 23-04-2016 DC74_RS04915 b69f5c4aa60cc41a2bf8cccde1ce48c6 562 SMART SM00382 352 534 4.3E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS04915 b69f5c4aa60cc41a2bf8cccde1ce48c6 562 Pfam PF00005 ABC transporter 357 486 6.0E-23 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS04915 b69f5c4aa60cc41a2bf8cccde1ce48c6 562 Gene3D G3DSA:1.20.1560.10 16 320 4.1E-19 T 23-04-2016 DC74_RS04915 b69f5c4aa60cc41a2bf8cccde1ce48c6 562 SUPERFAMILY SSF52540 356 512 3.85E-35 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04915 b69f5c4aa60cc41a2bf8cccde1ce48c6 562 Gene3D G3DSA:3.40.50.300 357 514 1.1E-35 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04915 b69f5c4aa60cc41a2bf8cccde1ce48c6 562 SUPERFAMILY SSF90123 7 318 3.92E-25 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS04915 b69f5c4aa60cc41a2bf8cccde1ce48c6 562 ProSitePatterns PS00211 ABC transporters family signature. 458 472 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS04915 b69f5c4aa60cc41a2bf8cccde1ce48c6 562 PANTHER PTHR24222:SF30 19 512 7.7E-57 T 23-04-2016 DC74_RS05575 37cd747d7268bbf8b1daeb218043e4f7 89 PANTHER PTHR33677:SF2 4 88 3.3E-33 T 23-04-2016 DC74_RS05575 37cd747d7268bbf8b1daeb218043e4f7 89 PANTHER PTHR33677 4 88 3.3E-33 T 23-04-2016 DC74_RS05575 37cd747d7268bbf8b1daeb218043e4f7 89 Pfam PF02583 Metal-sensitive transcriptional repressor 10 84 3.9E-24 T 23-04-2016 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 DC74_RS09540 df8984b0d0964f34a99053609dcc50f1 729 SUPERFAMILY SSF52540 14 246 2.91E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09540 df8984b0d0964f34a99053609dcc50f1 729 Gene3D G3DSA:1.25.40.10 416 520 5.3E-8 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS09540 df8984b0d0964f34a99053609dcc50f1 729 Gene3D G3DSA:1.25.40.10 521 629 7.6E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS09540 df8984b0d0964f34a99053609dcc50f1 729 SUPERFAMILY SSF48452 425 619 1.66E-13 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS09540 df8984b0d0964f34a99053609dcc50f1 729 Gene3D G3DSA:3.40.50.300 27 73 2.0E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09540 df8984b0d0964f34a99053609dcc50f1 729 PRINTS PR00364 Disease resistance protein signature 119 133 2.2E-6 T 23-04-2016 DC74_RS09540 df8984b0d0964f34a99053609dcc50f1 729 PRINTS PR00364 Disease resistance protein signature 213 227 2.2E-6 T 23-04-2016 DC74_RS09540 df8984b0d0964f34a99053609dcc50f1 729 PRINTS PR00364 Disease resistance protein signature 50 65 2.2E-6 T 23-04-2016 DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 Pfam PF02983 Alpha-lytic protease prodomain 85 140 2.0E-19 T 23-04-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 Gene3D G3DSA:2.40.10.10 157 241 2.2E-28 T 23-04-2016 DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 Gene3D G3DSA:2.40.10.10 242 329 1.5E-31 T 23-04-2016 DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 Gene3D G3DSA:3.30.300.50 17 83 8.2E-6 T 23-04-2016 DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 307 321 4.7E-44 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 243 263 4.7E-44 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 264 281 4.7E-44 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 283 306 4.7E-44 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 183 197 4.7E-44 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 PIRSF PIRSF001134 1 342 2.8E-128 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 292 303 - T 23-04-2016 IPR033116 Serine proteases, trypsin family, serine active site DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 Gene3D G3DSA:3.30.300.50 84 151 1.5E-13 T 23-04-2016 DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 SUPERFAMILY SSF50494 159 339 6.24E-37 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS10855 1cd2e65a69e9e981e5ef440eb42810ae 342 Pfam PF00089 Trypsin 183 332 5.8E-11 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS12030 22096a8408b319a9f4d5e4e1f74ad3d5 196 Pfam PF01121 Dephospho-CoA kinase 4 179 4.5E-60 T 23-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 DC74_RS12030 22096a8408b319a9f4d5e4e1f74ad3d5 196 SUPERFAMILY SSF52540 1 192 7.2E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12030 22096a8408b319a9f4d5e4e1f74ad3d5 196 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 28.086 T 23-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 DC74_RS12030 22096a8408b319a9f4d5e4e1f74ad3d5 196 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 187 7.0E-54 T 23-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 DC74_RS12030 22096a8408b319a9f4d5e4e1f74ad3d5 196 Gene3D G3DSA:3.40.50.300 1 195 1.1E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12030 22096a8408b319a9f4d5e4e1f74ad3d5 196 PANTHER PTHR10695 1 194 8.7E-78 T 23-04-2016 DC74_RS39490 14c691f1f0623175b3326d6fe619b4d2 124 PANTHER PTHR35908 1 122 1.3E-61 T 23-04-2016 DC74_RS39490 14c691f1f0623175b3326d6fe619b4d2 124 PANTHER PTHR35908:SF2 1 122 1.3E-61 T 23-04-2016 DC74_RS39490 14c691f1f0623175b3326d6fe619b4d2 124 Gene3D G3DSA:3.10.180.10 3 122 4.6E-16 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS39490 14c691f1f0623175b3326d6fe619b4d2 124 SUPERFAMILY SSF54593 4 122 1.03E-18 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS18185 1a1c9fb2d06ca9e0e392369fe5e83e27 579 Gene3D G3DSA:2.30.40.10 1 71 1.2E-16 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS18185 1a1c9fb2d06ca9e0e392369fe5e83e27 579 Pfam PF07969 Amidohydrolase family 47 550 2.9E-67 T 23-04-2016 IPR013108 Amidohydrolase 3 DC74_RS18185 1a1c9fb2d06ca9e0e392369fe5e83e27 579 PANTHER PTHR22935:SF55 478 577 1.3E-12 T 23-04-2016 DC74_RS18185 1a1c9fb2d06ca9e0e392369fe5e83e27 579 PANTHER PTHR22935 478 577 1.3E-12 T 23-04-2016 DC74_RS18185 1a1c9fb2d06ca9e0e392369fe5e83e27 579 Gene3D G3DSA:3.20.20.140 72 307 2.4E-81 T 23-04-2016 DC74_RS18185 1a1c9fb2d06ca9e0e392369fe5e83e27 579 Gene3D G3DSA:3.20.20.140 424 484 2.4E-81 T 23-04-2016 DC74_RS18185 1a1c9fb2d06ca9e0e392369fe5e83e27 579 SUPERFAMILY SSF51338 1 57 8.06E-19 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS18185 1a1c9fb2d06ca9e0e392369fe5e83e27 579 SUPERFAMILY SSF51338 499 562 8.06E-19 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS18185 1a1c9fb2d06ca9e0e392369fe5e83e27 579 SUPERFAMILY SSF51556 58 315 7.31E-53 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS18185 1a1c9fb2d06ca9e0e392369fe5e83e27 579 SUPERFAMILY SSF51556 371 499 7.31E-53 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS18185 1a1c9fb2d06ca9e0e392369fe5e83e27 579 Gene3D G3DSA:2.30.40.10 485 517 2.5E-10 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS02570 4dc1072fb5b625d77404029d3d8b14dc 165 SUPERFAMILY SSF53927 4 117 1.47E-32 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS02570 4dc1072fb5b625d77404029d3d8b14dc 165 Gene3D G3DSA:3.40.140.10 3 135 5.2E-34 T 23-04-2016 DC74_RS02570 4dc1072fb5b625d77404029d3d8b14dc 165 Pfam PF14437 MafB19-like deaminase 9 90 1.4E-18 T 23-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 DC74_RS02570 4dc1072fb5b625d77404029d3d8b14dc 165 PANTHER PTHR11079 8 99 9.0E-25 T 23-04-2016 DC74_RS02570 4dc1072fb5b625d77404029d3d8b14dc 165 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 49 86 - T 23-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 DC74_RS01540 c17a0a1f47b4e0fe1f0c484676f596d4 120 Gene3D G3DSA:3.10.180.10 6 117 3.8E-41 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS01540 c17a0a1f47b4e0fe1f0c484676f596d4 120 SUPERFAMILY SSF54593 1 118 1.51E-19 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS01540 c17a0a1f47b4e0fe1f0c484676f596d4 120 PANTHER PTHR39175 1 120 1.0E-43 T 23-04-2016 DC74_RS01540 c17a0a1f47b4e0fe1f0c484676f596d4 120 PANTHER PTHR39175:SF1 1 120 1.0E-43 T 23-04-2016 DC74_RS01965 6b2aad7f4e8b3b03c8b850e5a58fab63 403 Pfam PF08281 Sigma-70, region 4 104 153 1.3E-9 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS01965 6b2aad7f4e8b3b03c8b850e5a58fab63 403 SUPERFAMILY SSF88946 5 92 2.55E-11 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS01965 6b2aad7f4e8b3b03c8b850e5a58fab63 403 Gene3D G3DSA:1.10.1740.10 5 95 4.9E-11 T 23-04-2016 DC74_RS01965 6b2aad7f4e8b3b03c8b850e5a58fab63 403 SUPERFAMILY SSF88659 99 156 3.92E-9 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS01965 6b2aad7f4e8b3b03c8b850e5a58fab63 403 Gene3D G3DSA:1.10.10.10 98 156 5.5E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01965 6b2aad7f4e8b3b03c8b850e5a58fab63 403 PANTHER PTHR30173:SF15 6 373 7.3E-131 T 23-04-2016 DC74_RS01965 6b2aad7f4e8b3b03c8b850e5a58fab63 403 PANTHER PTHR30173 6 373 7.3E-131 T 23-04-2016 DC74_RS01965 6b2aad7f4e8b3b03c8b850e5a58fab63 403 Pfam PF04542 Sigma-70 region 2 9 75 5.7E-9 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 PANTHER PTHR10357:SF26 32 444 1.9E-146 T 23-04-2016 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 PRINTS PR00110 Alpha-amylase signature 70 87 2.6E-24 T 23-04-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 PRINTS PR00110 Alpha-amylase signature 275 287 2.6E-24 T 23-04-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 PRINTS PR00110 Alpha-amylase signature 191 202 2.6E-24 T 23-04-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 PRINTS PR00110 Alpha-amylase signature 102 113 2.6E-24 T 23-04-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 PRINTS PR00110 Alpha-amylase signature 219 237 2.6E-24 T 23-04-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 SMART SM00632 364 446 2.8E-36 T 23-04-2016 IPR031319 Alpha-amylase, C-terminal domain DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 367 444 3.9E-14 T 23-04-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: REACT_474 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 SUPERFAMILY SSF51445 23 358 7.04E-78 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 SMART SM00642 27 355 3.2E-74 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 Pfam PF00128 Alpha amylase, catalytic domain 79 321 2.7E-17 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 Gene3D G3DSA:3.20.20.80 22 355 5.7E-92 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 PANTHER PTHR10357 32 444 1.9E-146 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 SUPERFAMILY SSF51011 362 444 9.0E-29 T 23-04-2016 DC74_RS34030 2681e6f760008aac4fa174a46410b508 446 Gene3D G3DSA:2.60.40.1180 362 445 8.4E-30 T 23-04-2016 IPR013780 Glycosyl hydrolase, all-beta DC74_RS10290 cde6f44f6920b9c91728b862a64d3990 314 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 222 310 1.4E-18 T 23-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 DC74_RS10290 cde6f44f6920b9c91728b862a64d3990 314 Gene3D G3DSA:3.10.50.40 206 312 6.1E-27 T 23-04-2016 DC74_RS10290 cde6f44f6920b9c91728b862a64d3990 314 SUPERFAMILY SSF54534 198 313 9.43E-26 T 23-04-2016 DC74_RS10290 cde6f44f6920b9c91728b862a64d3990 314 PANTHER PTHR10516:SF320 188 311 7.0E-25 T 23-04-2016 DC74_RS10290 cde6f44f6920b9c91728b862a64d3990 314 PANTHER PTHR10516:SF320 141 165 7.0E-25 T 23-04-2016 DC74_RS10290 cde6f44f6920b9c91728b862a64d3990 314 PANTHER PTHR10516 188 311 7.0E-25 T 23-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type DC74_RS10290 cde6f44f6920b9c91728b862a64d3990 314 PANTHER PTHR10516 141 165 7.0E-25 T 23-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type DC74_RS10290 cde6f44f6920b9c91728b862a64d3990 314 SUPERFAMILY SSF54534 40 170 9.43E-6 T 23-04-2016 DC74_RS10290 cde6f44f6920b9c91728b862a64d3990 314 Gene3D G3DSA:3.10.50.40 40 175 4.1E-5 T 23-04-2016 DC74_RS00940 870860ef96c59270492cb7fdfc7158a2 478 SUPERFAMILY SSF75304 4 465 7.98E-124 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS00940 870860ef96c59270492cb7fdfc7158a2 478 Gene3D G3DSA:3.90.1300.10 4 462 3.3E-126 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS00940 870860ef96c59270492cb7fdfc7158a2 478 PANTHER PTHR11895 3 467 7.1E-126 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS00940 870860ef96c59270492cb7fdfc7158a2 478 Pfam PF01425 Amidase 27 450 6.0E-100 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 SUPERFAMILY SSF46929 149 204 8.89E-8 T 23-04-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 Gene3D G3DSA:1.10.150.20 66 131 1.3E-24 T 23-04-2016 DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 203 26.434 T 23-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 PANTHER PTHR33796 2 205 3.8E-67 T 23-04-2016 DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 Pfam PF07499 RuvA, C-terminal domain 150 202 1.8E-10 T 23-04-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 SUPERFAMILY SSF50249 1 62 8.57E-14 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 183 3.6E-36 T 23-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 Gene3D G3DSA:2.40.50.140 1 64 5.3E-22 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 Pfam PF14520 Helix-hairpin-helix domain 71 129 3.3E-14 T 23-04-2016 DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 SMART SM00278 72 91 50.0 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 SMART SM00278 107 126 0.05 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 Gene3D G3DSA:1.10.8.10 144 206 1.9E-11 T 23-04-2016 DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 Pfam PF01330 RuvA N terminal domain 1 61 9.9E-19 T 23-04-2016 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 DC74_RS09615 1d9714a2e031159063d9de8925d0c942 206 SUPERFAMILY SSF47781 65 132 8.62E-18 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 Pfam PF05199 GMC oxidoreductase 440 539 1.6E-13 T 23-04-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 PANTHER PTHR10668:SF68 44 539 1.3E-52 T 23-04-2016 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 SUPERFAMILY SSF54373 362 493 7.65E-59 T 23-04-2016 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 SUPERFAMILY SSF51905 56 344 2.67E-37 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 SUPERFAMILY SSF51905 490 547 2.67E-37 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 152 175 - T 23-04-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 Pfam PF00732 GMC oxidoreductase 148 343 3.5E-6 T 23-04-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 PANTHER PTHR10668:SF68 1 27 1.3E-52 T 23-04-2016 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 Gene3D G3DSA:3.50.50.60 484 546 7.9E-71 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 Gene3D G3DSA:3.50.50.60 259 365 7.9E-71 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 Gene3D G3DSA:3.50.50.60 55 196 7.9E-71 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 PANTHER PTHR10668 44 539 1.3E-52 T 23-04-2016 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 PANTHER PTHR10668 1 27 1.3E-52 T 23-04-2016 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 Gene3D G3DSA:3.30.410.10 366 483 3.4E-81 T 23-04-2016 DC74_RS06775 4e072027a067958fd01f31f8f4680e95 553 Gene3D G3DSA:3.30.410.10 199 257 3.4E-81 T 23-04-2016 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 PANTHER PTHR11465 1 479 2.9E-291 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 Pfam PF00199 Catalase 7 389 1.7E-186 T 23-04-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 PRINTS PR00067 Catalase signature 83 101 1.7E-70 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 PRINTS PR00067 Catalase signature 104 121 1.7E-70 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 PRINTS PR00067 Catalase signature 288 315 1.7E-70 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 PRINTS PR00067 Catalase signature 20 43 1.7E-70 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 PRINTS PR00067 Catalase signature 320 346 1.7E-70 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 PRINTS PR00067 Catalase signature 123 141 1.7E-70 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 23-04-2016 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 Pfam PF06628 Catalase-related immune-responsive 417 478 6.6E-22 T 23-04-2016 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 Gene3D G3DSA:2.40.180.10 2 357 3.7E-178 T 23-04-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 SMART SM01060 7 392 6.7E-276 T 23-04-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 23-04-2016 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 PIRSF PIRSF038928 1 485 8.0E-221 T 23-04-2016 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS31310 9e5affd6da4d4f98857a2fb1cd30c711 485 SUPERFAMILY SSF56634 3 479 1.1E-205 T 23-04-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS22320 998ae4850dcd78f5eee98b4a9090a8ae 54 Pfam PF00471 Ribosomal protein L33 9 54 8.0E-17 T 23-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22320 998ae4850dcd78f5eee98b4a9090a8ae 54 SUPERFAMILY SSF57829 4 54 7.32E-18 T 23-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 DC74_RS22320 998ae4850dcd78f5eee98b4a9090a8ae 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 23-04-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22320 998ae4850dcd78f5eee98b4a9090a8ae 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 4.8E-23 T 23-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22320 998ae4850dcd78f5eee98b4a9090a8ae 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.798 T 23-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22320 998ae4850dcd78f5eee98b4a9090a8ae 54 PANTHER PTHR15238 1 53 5.5E-23 T 23-04-2016 DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 53 618 4.7E-152 T 23-04-2016 IPR005674 CocE/Serine esterase GO:0016787 DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 SUPERFAMILY SSF53474 37 395 1.59E-55 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 56 331 6.1E-64 T 23-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 PANTHER PTHR11731 263 330 3.2E-45 T 23-04-2016 DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 Gene3D G3DSA:3.40.50.1820 272 391 2.7E-82 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 Gene3D G3DSA:3.40.50.1820 29 186 2.7E-82 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 SUPERFAMILY SSF49785 387 618 3.83E-69 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 PANTHER PTHR11731:SF151 48 209 3.2E-45 T 23-04-2016 DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 Gene3D G3DSA:1.10.3020.10 187 271 3.5E-14 T 23-04-2016 DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 PANTHER PTHR11731 48 209 3.2E-45 T 23-04-2016 DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 378 612 6.1E-60 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 Gene3D G3DSA:2.60.120.260 393 619 5.9E-85 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 SMART SM00939 360 613 1.4E-91 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 DC74_RS01865 e6b0f3f0ad7cedbc718922d6e63ee936 632 PANTHER PTHR11731:SF151 263 330 3.2E-45 T 23-04-2016 DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 Gene3D G3DSA:3.40.50.2300 2 164 1.6E-37 T 23-04-2016 DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 Pfam PF00072 Response regulator receiver domain 5 119 3.3E-27 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 SUPERFAMILY SSF46894 157 223 6.12E-23 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 217 3.8E-19 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 SMART SM00448 3 118 2.6E-30 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 PANTHER PTHR26402 3 223 1.8E-88 T 23-04-2016 DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 6.2E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 6.2E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 6.2E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 Gene3D G3DSA:1.10.10.10 165 222 5.9E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 SMART SM00421 160 217 3.6E-27 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 SUPERFAMILY SSF52172 3 130 6.55E-33 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS12990 e739853cd5f3029e0dafc771384a5101 228 PANTHER PTHR26402:SF151 3 223 1.8E-88 T 23-04-2016 DC74_RS25455 83bd40df24a125852fd3503b20c1a31d 194 Gene3D G3DSA:1.10.357.10 72 194 1.4E-26 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS25455 83bd40df24a125852fd3503b20c1a31d 194 Gene3D G3DSA:1.10.10.60 1 64 6.3E-21 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS25455 83bd40df24a125852fd3503b20c1a31d 194 SUPERFAMILY SSF48498 80 193 1.11E-23 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS25455 83bd40df24a125852fd3503b20c1a31d 194 PANTHER PTHR30055 1 194 2.9E-42 T 23-04-2016 DC74_RS25455 83bd40df24a125852fd3503b20c1a31d 194 SUPERFAMILY SSF46689 2 76 3.14E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS25455 83bd40df24a125852fd3503b20c1a31d 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 2.1E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS25455 83bd40df24a125852fd3503b20c1a31d 194 PANTHER PTHR30055:SF34 1 194 2.9E-42 T 23-04-2016 DC74_RS15500 e357b7d4e17e70aea76e223dc856bdbe 318 PANTHER PTHR30193:SF6 1 242 9.3E-83 T 23-04-2016 DC74_RS15500 e357b7d4e17e70aea76e223dc856bdbe 318 PANTHER PTHR30193:SF6 258 308 9.3E-83 T 23-04-2016 DC74_RS15500 e357b7d4e17e70aea76e223dc856bdbe 318 PANTHER PTHR30193 1 242 9.3E-83 T 23-04-2016 DC74_RS15500 e357b7d4e17e70aea76e223dc856bdbe 318 PANTHER PTHR30193 258 308 9.3E-83 T 23-04-2016 DC74_RS15500 e357b7d4e17e70aea76e223dc856bdbe 318 Gene3D G3DSA:1.10.3720.10 12 307 5.8E-54 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS15500 e357b7d4e17e70aea76e223dc856bdbe 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 298 6.2E-6 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS15500 e357b7d4e17e70aea76e223dc856bdbe 318 SUPERFAMILY SSF161098 63 303 3.27E-49 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS14880 3e46d54532a8e103ade03eda5298f787 272 SUPERFAMILY SSF64005 34 257 9.94E-85 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 DC74_RS14880 3e46d54532a8e103ade03eda5298f787 272 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 261 7.2E-75 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 DC74_RS14880 3e46d54532a8e103ade03eda5298f787 272 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 23-04-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 DC74_RS14880 3e46d54532a8e103ade03eda5298f787 272 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 261 3.0E-79 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 DC74_RS14880 3e46d54532a8e103ade03eda5298f787 272 Gene3D G3DSA:3.40.1180.10 32 262 1.2E-91 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 DC74_RS14880 3e46d54532a8e103ade03eda5298f787 272 PANTHER PTHR10291:SF0 34 261 5.3E-121 T 23-04-2016 DC74_RS14880 3e46d54532a8e103ade03eda5298f787 272 PANTHER PTHR10291 34 261 5.3E-121 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 DC74_RS14880 3e46d54532a8e103ade03eda5298f787 272 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 262 38.166 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 DC74_RS28955 27b816ea682901daff46c7d73877751f 219 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 23-04-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 DC74_RS28955 27b816ea682901daff46c7d73877751f 219 PANTHER PTHR23029:SF26 1 204 1.8E-75 T 23-04-2016 DC74_RS28955 27b816ea682901daff46c7d73877751f 219 SUPERFAMILY SSF53254 4 199 4.45E-40 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS28955 27b816ea682901daff46c7d73877751f 219 Gene3D G3DSA:3.40.50.1240 4 201 2.9E-43 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS28955 27b816ea682901daff46c7d73877751f 219 SMART SM00855 6 166 5.4E-18 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS28955 27b816ea682901daff46c7d73877751f 219 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 199 1.1E-35 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS28955 27b816ea682901daff46c7d73877751f 219 PANTHER PTHR23029 1 204 1.8E-75 T 23-04-2016 DC74_RS32725 2db52ec27d652c032de27000a4621d98 410 SUPERFAMILY SSF55785 4 131 3.32E-13 T 23-04-2016 IPR000014 PAS domain DC74_RS32725 2db52ec27d652c032de27000a4621d98 410 SMART SM00331 197 410 5.2E-36 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS32725 2db52ec27d652c032de27000a4621d98 410 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 224 409 1.3E-43 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS32725 2db52ec27d652c032de27000a4621d98 410 PANTHER PTHR21021:SF19 144 154 1.3E-47 T 23-04-2016 DC74_RS32725 2db52ec27d652c032de27000a4621d98 410 PANTHER PTHR21021:SF19 173 410 1.3E-47 T 23-04-2016 DC74_RS32725 2db52ec27d652c032de27000a4621d98 410 PANTHER PTHR21021 173 410 1.3E-47 T 23-04-2016 DC74_RS32725 2db52ec27d652c032de27000a4621d98 410 SMART SM00091 5 71 3.2E-6 T 23-04-2016 IPR000014 PAS domain DC74_RS32725 2db52ec27d652c032de27000a4621d98 410 Gene3D G3DSA:3.30.450.20 6 132 8.4E-17 T 23-04-2016 DC74_RS32725 2db52ec27d652c032de27000a4621d98 410 Pfam PF08448 PAS fold 12 135 1.7E-11 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS32725 2db52ec27d652c032de27000a4621d98 410 SUPERFAMILY SSF81606 211 410 1.96E-10 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS32725 2db52ec27d652c032de27000a4621d98 410 PANTHER PTHR21021 144 154 1.3E-47 T 23-04-2016 DC74_RS11515 7c2f14ea2c27b971ae736d9547d33f94 502 SUPERFAMILY SSF52317 274 425 5.88E-37 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS11515 7c2f14ea2c27b971ae736d9547d33f94 502 SUPERFAMILY SSF52317 193 239 5.88E-37 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS11515 7c2f14ea2c27b971ae736d9547d33f94 502 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 489 171.443 T 23-04-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 DC74_RS11515 7c2f14ea2c27b971ae736d9547d33f94 502 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 226 1.6E-24 T 23-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DC74_RS11515 7c2f14ea2c27b971ae736d9547d33f94 502 Gene3D G3DSA:3.40.50.880 262 443 2.1E-39 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS11515 7c2f14ea2c27b971ae736d9547d33f94 502 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 481 6.1E-135 T 23-04-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 DC74_RS11515 7c2f14ea2c27b971ae736d9547d33f94 502 Gene3D G3DSA:3.40.50.300 5 237 6.9E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11515 7c2f14ea2c27b971ae736d9547d33f94 502 PANTHER PTHR21343 5 486 1.5E-198 T 23-04-2016 DC74_RS11515 7c2f14ea2c27b971ae736d9547d33f94 502 PANTHER PTHR21343:SF1 5 486 1.5E-198 T 23-04-2016 DC74_RS11515 7c2f14ea2c27b971ae736d9547d33f94 502 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 262 432 3.7E-44 T 23-04-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 DC74_RS11515 7c2f14ea2c27b971ae736d9547d33f94 502 SUPERFAMILY SSF52540 5 241 3.5E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37785 89ed97fe4ed8322be625669658e77fbd 217 SMART SM00116 13 61 2.0E-8 T 23-04-2016 IPR000644 CBS domain DC74_RS37785 89ed97fe4ed8322be625669658e77fbd 217 SMART SM00116 76 124 6.7E-10 T 23-04-2016 IPR000644 CBS domain DC74_RS37785 89ed97fe4ed8322be625669658e77fbd 217 SUPERFAMILY SSF54631 2 122 6.34E-35 T 23-04-2016 DC74_RS37785 89ed97fe4ed8322be625669658e77fbd 217 Gene3D G3DSA:3.10.580.10 5 123 3.6E-33 T 23-04-2016 DC74_RS37785 89ed97fe4ed8322be625669658e77fbd 217 Pfam PF00571 CBS domain 69 123 1.4E-16 T 23-04-2016 IPR000644 CBS domain DC74_RS37785 89ed97fe4ed8322be625669658e77fbd 217 Pfam PF00571 CBS domain 6 60 1.8E-12 T 23-04-2016 IPR000644 CBS domain DC74_RS37785 89ed97fe4ed8322be625669658e77fbd 217 Pfam PF04972 BON domain 127 193 1.7E-10 T 23-04-2016 IPR007055 BON domain DC74_RS37785 89ed97fe4ed8322be625669658e77fbd 217 PANTHER PTHR11911 1 134 3.6E-35 T 23-04-2016 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 Gene3D G3DSA:1.10.260.40 11 94 5.8E-29 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 Hamap MF_00535 Cyanate hydratase [cynS]. 1 164 73.842 T 23-04-2016 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 PRINTS PR01693 Cyanase signature 117 133 2.9E-30 T 23-04-2016 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 PRINTS PR01693 Cyanase signature 30 45 2.9E-30 T 23-04-2016 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 PRINTS PR01693 Cyanase signature 99 113 2.9E-30 T 23-04-2016 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 PRINTS PR01693 Cyanase signature 50 67 2.9E-30 T 23-04-2016 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 PRINTS PR01693 Cyanase signature 149 159 2.9E-30 T 23-04-2016 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 PIRSF PIRSF001263 11 164 5.2E-60 T 23-04-2016 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 SMART SM01116 91 164 8.2E-47 T 23-04-2016 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 SUPERFAMILY SSF55234 96 163 2.48E-29 T 23-04-2016 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 TIGRFAM TIGR00673 cynS: cyanase 21 164 2.7E-59 T 23-04-2016 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 SUPERFAMILY SSF47413 13 93 6.26E-19 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 Pfam PF02560 Cyanate lyase C-terminal domain 96 162 4.9E-32 T 23-04-2016 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 PANTHER PTHR34186 4 164 5.8E-69 T 23-04-2016 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 Gene3D G3DSA:3.30.1160.10 97 164 3.5E-36 T 23-04-2016 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DC74_RS02575 026755a19ad01001d7c1f318b234796f 164 PANTHER PTHR34186:SF2 4 164 5.8E-69 T 23-04-2016 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 287 294 - T 23-04-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 294 451 1.8E-43 T 23-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 PANTHER PTHR10836:SF35 117 476 2.0E-233 T 23-04-2016 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 SUPERFAMILY SSF55347 289 452 2.62E-49 T 23-04-2016 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 130 289 8.0E-40 T 23-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 131 463 8.7E-113 T 23-04-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 Gene3D G3DSA:3.30.360.10 298 453 9.4E-51 T 23-04-2016 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 SUPERFAMILY SSF51735 130 305 3.69E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 PANTHER PTHR10836 117 476 2.0E-233 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 Gene3D G3DSA:3.40.50.720 130 297 3.8E-50 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 247 260 1.7E-18 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 366 383 1.7E-18 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 283 301 1.7E-18 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 310 326 1.7E-18 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS06650 a02e76c9ed0655abe2ca436b3a7f1768 481 SMART SM00846 129 289 1.0E-53 T 23-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 DC74_RS13940 131a50cb9b36b592f0bfed65d8cba078 191 Pfam PF02342 TerD domain 3 187 5.3E-85 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS13940 131a50cb9b36b592f0bfed65d8cba078 191 PANTHER PTHR32097 2 191 5.1E-94 T 23-04-2016 DC74_RS13940 131a50cb9b36b592f0bfed65d8cba078 191 Gene3D G3DSA:2.60.60.30 18 185 3.3E-74 T 23-04-2016 DC74_RS12655 0ad1cc26a1116b34d7d48183f1e05597 216 SUPERFAMILY SSF51391 5 210 4.19E-59 T 23-04-2016 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 DC74_RS12655 0ad1cc26a1116b34d7d48183f1e05597 216 Pfam PF02581 Thiamine monophosphate synthase/TENI 13 194 3.5E-49 T 23-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 DC74_RS12655 0ad1cc26a1116b34d7d48183f1e05597 216 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 12 207 8.9E-59 T 23-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 DC74_RS12655 0ad1cc26a1116b34d7d48183f1e05597 216 PANTHER PTHR20857 1 213 4.7E-60 T 23-04-2016 DC74_RS12655 0ad1cc26a1116b34d7d48183f1e05597 216 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 10 212 23.315 T 23-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 DC74_RS12655 0ad1cc26a1116b34d7d48183f1e05597 216 PANTHER PTHR20857:SF15 1 213 4.7E-60 T 23-04-2016 DC74_RS12655 0ad1cc26a1116b34d7d48183f1e05597 216 Gene3D G3DSA:3.20.20.70 4 213 2.5E-70 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS35965 2bdf6aa5ef962b3a7253c51d6c5f6093 327 Pfam PF05231 MASE1 21 294 1.8E-42 T 23-04-2016 IPR007895 MASE1 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 Gene3D G3DSA:3.30.300.30 840 927 4.7E-20 T 23-04-2016 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 PRINTS PR00359 B-class P450 signature 358 367 1.6E-25 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 PRINTS PR00359 B-class P450 signature 309 336 1.6E-25 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 PRINTS PR00359 B-class P450 signature 102 113 1.6E-25 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 PRINTS PR00359 B-class P450 signature 337 352 1.6E-25 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 PRINTS PR00359 B-class P450 signature 209 231 1.6E-25 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 PRINTS PR00359 B-class P450 signature 148 164 1.6E-25 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 Pfam PF00550 Phosphopantetheine attachment site 962 1025 6.6E-9 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 SUPERFAMILY SSF56801 454 927 1.83E-122 T 23-04-2016 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 482 870 8.9E-113 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 ProSitePatterns PS00455 Putative AMP-binding domain signature. 596 607 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 SUPERFAMILY SSF47336 954 1026 1.44E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 Pfam PF13193 AMP-binding enzyme C-terminal domain 854 923 2.9E-6 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 Pfam PF00501 AMP-binding enzyme 461 846 1.1E-77 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 Gene3D G3DSA:2.30.38.10 758 836 1.2E-19 T 23-04-2016 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 Gene3D G3DSA:1.10.630.10 20 419 4.9E-76 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 Gene3D G3DSA:1.10.1200.10 952 1029 1.6E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 PANTHER PTHR24095 458 923 2.0E-150 T 23-04-2016 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 360 369 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 Gene3D G3DSA:3.40.50.980 618 757 1.6E-35 T 23-04-2016 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 Gene3D G3DSA:3.40.50.980 456 617 3.8E-41 T 23-04-2016 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 Pfam PF00067 Cytochrome P450 248 385 1.8E-10 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03455 09cf17a947cd912490fba7d7a799c71f 1033 SUPERFAMILY SSF48264 19 418 7.47E-59 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35065 01435aa36bf5622c94224269e19c999d 277 SUPERFAMILY SSF53335 23 232 1.32E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS35065 01435aa36bf5622c94224269e19c999d 277 Gene3D G3DSA:3.40.50.150 8 261 7.6E-66 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS35065 01435aa36bf5622c94224269e19c999d 277 PANTHER PTHR12176:SF22 12 243 1.2E-102 T 23-04-2016 DC74_RS35065 01435aa36bf5622c94224269e19c999d 277 PANTHER PTHR12176 12 243 1.2E-102 T 23-04-2016 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 Gene3D G3DSA:3.50.50.60 111 323 5.3E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 PANTHER PTHR22912:SF180 3 404 4.6E-143 T 23-04-2016 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 SUPERFAMILY SSF55424 326 419 3.16E-27 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 Gene3D G3DSA:3.50.50.60 4 110 1.4E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 PANTHER PTHR22912 3 404 4.6E-143 T 23-04-2016 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 3.9E-23 T 23-04-2016 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.9E-23 T 23-04-2016 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 3.9E-23 T 23-04-2016 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 3.9E-23 T 23-04-2016 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 3.9E-23 T 23-04-2016 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 Pfam PF14759 Reductase C-terminal 333 419 9.3E-17 T 23-04-2016 IPR028202 Reductase, C-terminal DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 2.6E-15 T 23-04-2016 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 2.6E-15 T 23-04-2016 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.6E-15 T 23-04-2016 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 2.6E-15 T 23-04-2016 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 SUPERFAMILY SSF51905 153 323 9.78E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 313 1.4E-60 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 Gene3D G3DSA:3.30.390.30 333 419 4.7E-31 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS14605 2ef42f499491481e02f065542c32bfdd 420 SUPERFAMILY SSF51905 3 198 2.31E-44 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS15970 2fa736cb1a45ac194feb8287376ec29f 350 Pfam PF00704 Glycosyl hydrolases family 18 75 280 1.9E-10 T 23-04-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 DC74_RS15970 2fa736cb1a45ac194feb8287376ec29f 350 PANTHER PTHR11177:SF203 31 316 4.1E-100 T 23-04-2016 DC74_RS15970 2fa736cb1a45ac194feb8287376ec29f 350 PANTHER PTHR11177 31 316 4.1E-100 T 23-04-2016 DC74_RS15970 2fa736cb1a45ac194feb8287376ec29f 350 SUPERFAMILY SSF51445 60 320 6.56E-25 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS15970 2fa736cb1a45ac194feb8287376ec29f 350 Gene3D G3DSA:3.20.20.80 77 320 9.2E-11 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS26365 1cdb6f629f2420b805b097b06ad5d3ca 233 PANTHER PTHR30173 33 206 5.1E-50 T 23-04-2016 DC74_RS26365 1cdb6f629f2420b805b097b06ad5d3ca 233 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 24 210 4.0E-109 T 23-04-2016 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26365 1cdb6f629f2420b805b097b06ad5d3ca 233 Pfam PF04542 Sigma-70 region 2 40 103 5.6E-18 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26365 1cdb6f629f2420b805b097b06ad5d3ca 233 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 198 4.4E-26 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26365 1cdb6f629f2420b805b097b06ad5d3ca 233 SUPERFAMILY SSF88946 32 118 9.16E-24 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26365 1cdb6f629f2420b805b097b06ad5d3ca 233 PANTHER PTHR30173:SF9 33 206 5.1E-50 T 23-04-2016 DC74_RS26365 1cdb6f629f2420b805b097b06ad5d3ca 233 SUPERFAMILY SSF88659 138 200 4.3E-16 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26365 1cdb6f629f2420b805b097b06ad5d3ca 233 Gene3D G3DSA:1.10.10.10 138 202 4.6E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26365 1cdb6f629f2420b805b097b06ad5d3ca 233 Gene3D G3DSA:1.10.1740.10 28 105 3.1E-28 T 23-04-2016 DC74_RS26365 1cdb6f629f2420b805b097b06ad5d3ca 233 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 58 89 - T 23-04-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26365 1cdb6f629f2420b805b097b06ad5d3ca 233 Pfam PF08281 Sigma-70, region 4 145 195 1.5E-13 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS16590 6b2f65a7a4067f8fe535738bc9a6937b 286 Gene3D G3DSA:1.10.10.10 5 83 3.9E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16590 6b2f65a7a4067f8fe535738bc9a6937b 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 3.2E-20 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS16590 6b2f65a7a4067f8fe535738bc9a6937b 286 Pfam PF03466 LysR substrate binding domain 90 279 1.0E-23 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS16590 6b2f65a7a4067f8fe535738bc9a6937b 286 Gene3D G3DSA:3.40.190.10 175 258 1.1E-12 T 23-04-2016 DC74_RS16590 6b2f65a7a4067f8fe535738bc9a6937b 286 SUPERFAMILY SSF53850 90 278 4.52E-23 T 23-04-2016 DC74_RS16590 6b2f65a7a4067f8fe535738bc9a6937b 286 PANTHER PTHR30346 5 277 8.7E-49 T 23-04-2016 DC74_RS16590 6b2f65a7a4067f8fe535738bc9a6937b 286 Gene3D G3DSA:3.40.190.10 90 174 1.4E-6 T 23-04-2016 DC74_RS16590 6b2f65a7a4067f8fe535738bc9a6937b 286 SUPERFAMILY SSF46785 6 84 1.71E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16590 6b2f65a7a4067f8fe535738bc9a6937b 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 6.2E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS16590 6b2f65a7a4067f8fe535738bc9a6937b 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 6.2E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS16590 6b2f65a7a4067f8fe535738bc9a6937b 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 6.2E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS28255 5780960a677f70b7b4d0f95966fb1946 135 SUPERFAMILY SSF46785 4 122 7.63E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28255 5780960a677f70b7b4d0f95966fb1946 135 Pfam PF12802 MarR family 31 89 6.5E-11 T 23-04-2016 DC74_RS28255 5780960a677f70b7b4d0f95966fb1946 135 SMART SM00347 23 125 1.7E-10 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS28255 5780960a677f70b7b4d0f95966fb1946 135 PANTHER PTHR33164 4 118 5.2E-25 T 23-04-2016 DC74_RS28255 5780960a677f70b7b4d0f95966fb1946 135 PANTHER PTHR33164:SF15 4 118 5.2E-25 T 23-04-2016 DC74_RS28255 5780960a677f70b7b4d0f95966fb1946 135 Gene3D G3DSA:1.10.10.10 4 121 1.1E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28255 5780960a677f70b7b4d0f95966fb1946 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 4.5E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS28255 5780960a677f70b7b4d0f95966fb1946 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 4.5E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS28255 5780960a677f70b7b4d0f95966fb1946 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 4.5E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS36655 426a9759700d8bf1e53668a20014eb1b 479 PANTHER PTHR33392:SF7 3 443 9.6E-84 T 23-04-2016 DC74_RS36655 426a9759700d8bf1e53668a20014eb1b 479 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 361 443 2.3E-14 T 23-04-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain DC74_RS36655 426a9759700d8bf1e53668a20014eb1b 479 PANTHER PTHR33392 3 443 9.6E-84 T 23-04-2016 DC74_RS36655 426a9759700d8bf1e53668a20014eb1b 479 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 73 242 8.1E-37 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS36655 426a9759700d8bf1e53668a20014eb1b 479 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 72 241 1.9E-35 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS31100 296b0d1b6094e244743b8d647893019f 376 Pfam PF03193 Protein of unknown function, DUF258 102 277 5.6E-43 T 23-04-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 DC74_RS31100 296b0d1b6094e244743b8d647893019f 376 Gene3D G3DSA:1.10.40.50 280 342 9.2E-23 T 23-04-2016 DC74_RS31100 296b0d1b6094e244743b8d647893019f 376 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 34 341 29.918 T 23-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 DC74_RS31100 296b0d1b6094e244743b8d647893019f 376 PANTHER PTHR32120:SF8 12 371 5.5E-128 T 23-04-2016 DC74_RS31100 296b0d1b6094e244743b8d647893019f 376 SUPERFAMILY SSF52540 120 338 1.13E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS31100 296b0d1b6094e244743b8d647893019f 376 PANTHER PTHR32120 12 371 5.5E-128 T 23-04-2016 DC74_RS31100 296b0d1b6094e244743b8d647893019f 376 Gene3D G3DSA:3.40.50.300 120 274 1.4E-37 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS31100 296b0d1b6094e244743b8d647893019f 376 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 77 333 1.4E-45 T 23-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 DC74_RS12305 33e558d70601bbcf5d78acecc2cab220 269 Gene3D G3DSA:3.20.20.70 2 259 1.3E-93 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS12305 33e558d70601bbcf5d78acecc2cab220 269 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 255 1.2E-79 T 23-04-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 DC74_RS12305 33e558d70601bbcf5d78acecc2cab220 269 PANTHER PTHR22854:SF2 2 258 1.4E-99 T 23-04-2016 DC74_RS12305 33e558d70601bbcf5d78acecc2cab220 269 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 34 253 29.302 T 23-04-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 DC74_RS12305 33e558d70601bbcf5d78acecc2cab220 269 PANTHER PTHR22854 2 258 1.4E-99 T 23-04-2016 DC74_RS12305 33e558d70601bbcf5d78acecc2cab220 269 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 68 - T 23-04-2016 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 DC74_RS12305 33e558d70601bbcf5d78acecc2cab220 269 SUPERFAMILY SSF51366 12 257 1.18E-76 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 DC74_RS12305 33e558d70601bbcf5d78acecc2cab220 269 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 257 33.454 T 23-04-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 Pfam PF00561 alpha/beta hydrolase fold 31 309 3.9E-29 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 SUPERFAMILY SSF53474 4 322 3.71E-63 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 PANTHER PTHR10992 3 167 3.8E-69 T 23-04-2016 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 4.3E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 4.3E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 Gene3D G3DSA:3.40.50.1820 215 323 3.2E-71 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 Gene3D G3DSA:3.40.50.1820 3 182 3.2E-71 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 PRINTS PR00412 Epoxide hydrolase signature 115 128 1.8E-23 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 PRINTS PR00412 Epoxide hydrolase signature 265 281 1.8E-23 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 PRINTS PR00412 Epoxide hydrolase signature 101 114 1.8E-23 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 PRINTS PR00412 Epoxide hydrolase signature 297 319 1.8E-23 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 PRINTS PR00412 Epoxide hydrolase signature 35 53 1.8E-23 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 PRINTS PR00412 Epoxide hydrolase signature 55 70 1.8E-23 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 PANTHER PTHR10992:SF305 3 167 3.8E-69 T 23-04-2016 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 PANTHER PTHR10992 209 322 3.8E-69 T 23-04-2016 DC74_RS37440 90a2119a4de1d46ac1cfc506e70d4798 324 PANTHER PTHR10992:SF305 209 322 3.8E-69 T 23-04-2016 DC74_RS01320 19c8edca6413d81bf875ca92bb74392f 315 PANTHER PTHR33824:SF2 1 272 3.7E-83 T 23-04-2016 DC74_RS01320 19c8edca6413d81bf875ca92bb74392f 315 SUPERFAMILY SSF55961 107 238 9.9E-20 T 23-04-2016 DC74_RS01320 19c8edca6413d81bf875ca92bb74392f 315 Gene3D G3DSA:3.30.530.20 110 214 1.2E-6 T 23-04-2016 IPR023393 START-like domain DC74_RS01320 19c8edca6413d81bf875ca92bb74392f 315 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 115 232 9.5E-14 T 23-04-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain DC74_RS01320 19c8edca6413d81bf875ca92bb74392f 315 PANTHER PTHR33824 1 272 3.7E-83 T 23-04-2016 DC74_RS06795 0bd9ac227cb5a5718be26e3052c148e2 63 Pfam PF06902 Divergent 4Fe-4S mono-cluster 2 60 1.1E-12 T 23-04-2016 IPR010693 Divergent 4Fe-4S mono-cluster DC74_RS06795 0bd9ac227cb5a5718be26e3052c148e2 63 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 6.4E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS06795 0bd9ac227cb5a5718be26e3052c148e2 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 6.4E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS06795 0bd9ac227cb5a5718be26e3052c148e2 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 6.4E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS06795 0bd9ac227cb5a5718be26e3052c148e2 63 PANTHER PTHR36923 1 62 1.2E-19 T 23-04-2016 DC74_RS06795 0bd9ac227cb5a5718be26e3052c148e2 63 SUPERFAMILY SSF54862 2 60 4.75E-13 T 23-04-2016 DC74_RS06795 0bd9ac227cb5a5718be26e3052c148e2 63 PANTHER PTHR36923:SF1 1 62 1.2E-19 T 23-04-2016 DC74_RS06795 0bd9ac227cb5a5718be26e3052c148e2 63 Gene3D G3DSA:3.30.70.20 1 62 9.9E-15 T 23-04-2016 DC74_RS37200 3f000d3f2a58e20c9e57c267ed41b33c 314 Pfam PF13602 Zinc-binding dehydrogenase 191 311 3.6E-12 T 23-04-2016 DC74_RS37200 3f000d3f2a58e20c9e57c267ed41b33c 314 PANTHER PTHR11695 15 314 5.2E-60 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS37200 3f000d3f2a58e20c9e57c267ed41b33c 314 SMART SM00829 10 311 1.3E-11 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS37200 3f000d3f2a58e20c9e57c267ed41b33c 314 Gene3D G3DSA:3.90.180.10 1 201 2.9E-50 T 23-04-2016 IPR011032 GroES-like DC74_RS37200 3f000d3f2a58e20c9e57c267ed41b33c 314 SUPERFAMILY SSF50129 1 143 7.46E-35 T 23-04-2016 IPR011032 GroES-like DC74_RS37200 3f000d3f2a58e20c9e57c267ed41b33c 314 SUPERFAMILY SSF51735 121 246 1.01E-20 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37200 3f000d3f2a58e20c9e57c267ed41b33c 314 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 96 2.0E-8 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS12570 894298e8510690bf16887be3ae77b580 589 Pfam PF00905 Penicillin binding protein transpeptidase domain 248 562 1.3E-73 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS12570 894298e8510690bf16887be3ae77b580 589 Pfam PF03717 Penicillin-binding Protein dimerisation domain 34 202 4.1E-13 T 23-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 DC74_RS12570 894298e8510690bf16887be3ae77b580 589 Gene3D G3DSA:3.40.710.10 230 568 7.7E-91 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS12570 894298e8510690bf16887be3ae77b580 589 PANTHER PTHR30627 141 587 2.1E-187 T 23-04-2016 DC74_RS12570 894298e8510690bf16887be3ae77b580 589 PANTHER PTHR30627 1 124 2.1E-187 T 23-04-2016 DC74_RS12570 894298e8510690bf16887be3ae77b580 589 SUPERFAMILY SSF56519 31 222 7.72E-34 T 23-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 DC74_RS12570 894298e8510690bf16887be3ae77b580 589 Gene3D G3DSA:3.90.1310.10 143 229 1.9E-25 T 23-04-2016 DC74_RS12570 894298e8510690bf16887be3ae77b580 589 SUPERFAMILY SSF56601 175 575 8.71E-86 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS12570 894298e8510690bf16887be3ae77b580 589 PANTHER PTHR30627:SF1 141 587 2.1E-187 T 23-04-2016 DC74_RS12570 894298e8510690bf16887be3ae77b580 589 PANTHER PTHR30627:SF1 1 124 2.1E-187 T 23-04-2016 DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 Pfam PF00571 CBS domain 290 337 4.7E-5 T 23-04-2016 IPR000644 CBS domain DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 Pfam PF00571 CBS domain 220 273 0.0014 T 23-04-2016 IPR000644 CBS domain DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 PANTHER PTHR22777 1 446 2.4E-243 T 23-04-2016 DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 SMART SM00116 227 276 0.044 T 23-04-2016 IPR000644 CBS domain DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 SMART SM00116 290 337 32.0 T 23-04-2016 IPR000644 CBS domain DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 SUPERFAMILY SSF56176 363 435 2.54E-15 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 Gene3D G3DSA:3.30.465.10 332 433 7.9E-23 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 SUPERFAMILY SSF54631 210 347 1.26E-25 T 23-04-2016 DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 SMART SM01091 357 434 3.9E-18 T 23-04-2016 IPR005170 Transporter-associated domain DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 Pfam PF01595 Domain of unknown function DUF21 10 202 8.0E-36 T 23-04-2016 IPR002550 Domain of unknown function DUF21 DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 Gene3D G3DSA:3.10.580.10 210 331 3.8E-18 T 23-04-2016 DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 PANTHER PTHR22777:SF5 1 446 2.4E-243 T 23-04-2016 DC74_RS09190 45636546f57ce9d0ec47520617aca791 454 Pfam PF03471 Transporter associated domain 363 432 1.7E-14 T 23-04-2016 IPR005170 Transporter-associated domain DC74_RS21245 e2dc02b4d6658c503b864f89007f0350 262 Pfam PF01061 ABC-2 type transporter 12 224 3.9E-26 T 23-04-2016 IPR013525 ABC-2 type transporter GO:0016020 DC74_RS21245 e2dc02b4d6658c503b864f89007f0350 262 PIRSF PIRSF006648 1 261 6.6E-65 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS21245 e2dc02b4d6658c503b864f89007f0350 262 PANTHER PTHR30294:SF24 10 257 1.0E-77 T 23-04-2016 DC74_RS21245 e2dc02b4d6658c503b864f89007f0350 262 PANTHER PTHR30294 10 257 1.0E-77 T 23-04-2016 DC74_RS26155 6527c6bb6dea252e481b83fbfdfd9ce4 284 SUPERFAMILY SSF109854 13 170 3.89E-14 T 23-04-2016 DC74_RS26155 6527c6bb6dea252e481b83fbfdfd9ce4 284 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 24 164 7.2E-11 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS26155 6527c6bb6dea252e481b83fbfdfd9ce4 284 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 24 249 2.2E-20 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS23290 880789ddbd6bbb9204e8ec947b834bbf 225 PANTHER PTHR10010 1 216 1.2E-58 T 23-04-2016 DC74_RS23290 880789ddbd6bbb9204e8ec947b834bbf 225 PIRSF PIRSF003107 1 217 3.9E-55 T 23-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 DC74_RS23290 880789ddbd6bbb9204e8ec947b834bbf 225 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 4.8E-58 T 23-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 DC74_RS23290 880789ddbd6bbb9204e8ec947b834bbf 225 Gene3D G3DSA:1.20.58.220 116 215 7.2E-22 T 23-04-2016 DC74_RS23290 880789ddbd6bbb9204e8ec947b834bbf 225 SUPERFAMILY SSF109755 2 217 9.73E-59 T 23-04-2016 DC74_RS23290 880789ddbd6bbb9204e8ec947b834bbf 225 Pfam PF01895 PhoU domain 121 204 5.1E-13 T 23-04-2016 IPR026022 PhoU domain DC74_RS23290 880789ddbd6bbb9204e8ec947b834bbf 225 Pfam PF01895 PhoU domain 16 103 3.1E-17 T 23-04-2016 IPR026022 PhoU domain DC74_RS23290 880789ddbd6bbb9204e8ec947b834bbf 225 Gene3D G3DSA:1.20.58.220 1 105 1.4E-28 T 23-04-2016 DC74_RS23290 880789ddbd6bbb9204e8ec947b834bbf 225 PANTHER PTHR10010:SF14 1 216 1.2E-58 T 23-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 DC74_RS16210 f7e6f04a79d175c29efc94eefb33b144 379 Gene3D G3DSA:1.10.10.10 28 97 8.6E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16210 f7e6f04a79d175c29efc94eefb33b144 379 PANTHER PTHR18964 79 153 3.3E-19 T 23-04-2016 DC74_RS16210 f7e6f04a79d175c29efc94eefb33b144 379 Gene3D G3DSA:3.30.420.40 98 157 2.4E-11 T 23-04-2016 DC74_RS16210 f7e6f04a79d175c29efc94eefb33b144 379 SUPERFAMILY SSF46785 28 93 3.55E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16210 f7e6f04a79d175c29efc94eefb33b144 379 PANTHER PTHR18964:SF124 79 153 3.3E-19 T 23-04-2016 DC74_RS28635 dec8186b7771fc0bcd040ad22d0ae115 225 PANTHER PTHR30244:SF16 7 97 4.7E-20 T 23-04-2016 DC74_RS28635 dec8186b7771fc0bcd040ad22d0ae115 225 Gene3D G3DSA:3.40.640.10 7 97 5.5E-22 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS28635 dec8186b7771fc0bcd040ad22d0ae115 225 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 107 212 9.7E-9 T 23-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase DC74_RS28635 dec8186b7771fc0bcd040ad22d0ae115 225 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 6 94 8.5E-26 T 23-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase DC74_RS28635 dec8186b7771fc0bcd040ad22d0ae115 225 PANTHER PTHR30244 7 97 4.7E-20 T 23-04-2016 DC74_RS28635 dec8186b7771fc0bcd040ad22d0ae115 225 SUPERFAMILY SSF53383 5 213 1.82E-31 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS28635 dec8186b7771fc0bcd040ad22d0ae115 225 Gene3D G3DSA:3.90.1150.10 107 217 1.6E-18 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS06560 ff84370aca8c535783e08df4f48ad963 271 PANTHER PTHR24220 10 265 8.6E-90 T 23-04-2016 DC74_RS06560 ff84370aca8c535783e08df4f48ad963 271 SUPERFAMILY SSF52540 9 236 2.53E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06560 ff84370aca8c535783e08df4f48ad963 271 SMART SM00382 38 218 1.5E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS06560 ff84370aca8c535783e08df4f48ad963 271 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS06560 ff84370aca8c535783e08df4f48ad963 271 Gene3D G3DSA:3.40.50.300 4 217 2.0E-69 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06560 ff84370aca8c535783e08df4f48ad963 271 PANTHER PTHR24220:SF561 10 265 8.6E-90 T 23-04-2016 DC74_RS06560 ff84370aca8c535783e08df4f48ad963 271 Pfam PF00005 ABC transporter 30 168 7.8E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS03300 5dd8c8c7dfb24bf7354ddf2fbdd5cda4 167 SUPERFAMILY SSF46689 6 129 9.86E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03300 5dd8c8c7dfb24bf7354ddf2fbdd5cda4 167 Pfam PF13384 Homeodomain-like domain 13 60 3.0E-8 T 23-04-2016 DC74_RS03300 5dd8c8c7dfb24bf7354ddf2fbdd5cda4 167 Gene3D G3DSA:1.10.10.60 16 63 2.3E-4 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03300 5dd8c8c7dfb24bf7354ddf2fbdd5cda4 167 Pfam PF13592 Winged helix-turn helix 95 153 4.8E-20 T 23-04-2016 IPR025959 Winged helix-turn helix domain DC74_RS12680 1cacc5379c7b1097aa528d2134b75016 246 SUPERFAMILY SSF110399 1 224 4.45E-74 T 23-04-2016 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892|UniPathway: UPA00060 DC74_RS12680 1cacc5379c7b1097aa528d2134b75016 246 Gene3D G3DSA:3.20.20.70 2 233 4.6E-52 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS12680 1cacc5379c7b1097aa528d2134b75016 246 PANTHER PTHR34266 1 243 4.6E-139 T 23-04-2016 DC74_RS12680 1cacc5379c7b1097aa528d2134b75016 246 Pfam PF05690 Thiazole biosynthesis protein ThiG 1 232 1.3E-99 T 23-04-2016 DC74_RS08675 53ae370f6fe6e5c36197248c6ed247c8 371 SUPERFAMILY SSF55315 282 371 3.24E-5 T 23-04-2016 IPR029064 50S ribosomal protein L30e-like DC74_RS20470 bb2fd2d92b785ae32b3b80bf373dbfc8 88 Pfam PF06243 Phenylacetic acid degradation B 1 84 1.5E-38 T 23-04-2016 IPR009359 Phenylacetic acid degradation B UniPathway: UPA00930 DC74_RS20470 bb2fd2d92b785ae32b3b80bf373dbfc8 88 PIRSF PIRSF030200 1 88 9.5E-41 T 23-04-2016 IPR009359 Phenylacetic acid degradation B UniPathway: UPA00930 DC74_RS20470 bb2fd2d92b785ae32b3b80bf373dbfc8 88 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 1 87 6.8E-41 T 23-04-2016 IPR009359 Phenylacetic acid degradation B UniPathway: UPA00930 DC74_RS26340 7359d7a916e8f50a44bc8b1f09492232 335 SUPERFAMILY SSF52540 113 331 3.65E-40 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26340 7359d7a916e8f50a44bc8b1f09492232 335 Gene3D G3DSA:3.40.50.300 113 270 6.2E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26340 7359d7a916e8f50a44bc8b1f09492232 335 Pfam PF03193 Protein of unknown function, DUF258 95 270 1.3E-43 T 23-04-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 DC74_RS26340 7359d7a916e8f50a44bc8b1f09492232 335 Gene3D G3DSA:1.10.40.50 272 332 3.6E-12 T 23-04-2016 DC74_RS26340 7359d7a916e8f50a44bc8b1f09492232 335 PANTHER PTHR32120:SF2 33 333 4.5E-71 T 23-04-2016 DC74_RS26340 7359d7a916e8f50a44bc8b1f09492232 335 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 71 321 1.9E-42 T 23-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 DC74_RS26340 7359d7a916e8f50a44bc8b1f09492232 335 PANTHER PTHR32120 33 333 4.5E-71 T 23-04-2016 DC74_RS26340 7359d7a916e8f50a44bc8b1f09492232 335 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 36 333 26.85 T 23-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 DC74_RS12765 42a7cbaaed56f4979b0b24ddf1fa0fea 313 SUPERFAMILY SSF53067 2 312 1.61E-69 T 23-04-2016 DC74_RS12765 42a7cbaaed56f4979b0b24ddf1fa0fea 313 Gene3D G3DSA:3.30.420.40 135 286 1.4E-51 T 23-04-2016 DC74_RS12765 42a7cbaaed56f4979b0b24ddf1fa0fea 313 Pfam PF00480 ROK family 4 312 1.9E-101 T 23-04-2016 IPR000600 ROK family DC74_RS12765 42a7cbaaed56f4979b0b24ddf1fa0fea 313 Gene3D G3DSA:3.30.420.40 1 134 5.9E-46 T 23-04-2016 DC74_RS12765 42a7cbaaed56f4979b0b24ddf1fa0fea 313 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 5 311 7.9E-131 T 23-04-2016 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 DC74_RS12765 42a7cbaaed56f4979b0b24ddf1fa0fea 313 PANTHER PTHR18964:SF108 2 312 9.0E-92 T 23-04-2016 DC74_RS12765 42a7cbaaed56f4979b0b24ddf1fa0fea 313 PANTHER PTHR18964 2 312 9.0E-92 T 23-04-2016 DC74_RS12765 42a7cbaaed56f4979b0b24ddf1fa0fea 313 ProSitePatterns PS01125 ROK family signature. 130 157 - T 23-04-2016 IPR000600 ROK family DC74_RS37905 adbac1d6f07ee2e639d21eed979060f2 263 SUPERFAMILY SSF100950 83 241 5.44E-21 T 23-04-2016 DC74_RS37905 adbac1d6f07ee2e639d21eed979060f2 263 Pfam PF08220 DeoR-like helix-turn-helix domain 14 65 2.5E-9 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS37905 adbac1d6f07ee2e639d21eed979060f2 263 Pfam PF00455 DeoR C terminal sensor domain 83 238 8.8E-36 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain DC74_RS37905 adbac1d6f07ee2e639d21eed979060f2 263 SMART SM00420 14 66 6.9E-6 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS37905 adbac1d6f07ee2e639d21eed979060f2 263 ProSitePatterns PS00894 DeoR-type HTH domain signature. 14 48 - T 23-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 DC74_RS37905 adbac1d6f07ee2e639d21eed979060f2 263 SMART SM01134 81 240 8.5E-42 T 23-04-2016 DC74_RS37905 adbac1d6f07ee2e639d21eed979060f2 263 PANTHER PTHR30363 8 261 4.0E-48 T 23-04-2016 DC74_RS37905 adbac1d6f07ee2e639d21eed979060f2 263 Gene3D G3DSA:3.40.50.1360 85 221 2.3E-8 T 23-04-2016 DC74_RS37905 adbac1d6f07ee2e639d21eed979060f2 263 SUPERFAMILY SSF46785 11 71 3.1E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37905 adbac1d6f07ee2e639d21eed979060f2 263 PANTHER PTHR30363:SF1 8 261 4.0E-48 T 23-04-2016 DC74_RS37905 adbac1d6f07ee2e639d21eed979060f2 263 Gene3D G3DSA:1.10.10.10 11 60 7.7E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38100 24ff57a9627c03bccd1ad440a5382b21 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.3E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38100 24ff57a9627c03bccd1ad440a5382b21 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.3E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38100 24ff57a9627c03bccd1ad440a5382b21 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.3E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38100 24ff57a9627c03bccd1ad440a5382b21 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.3E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38100 24ff57a9627c03bccd1ad440a5382b21 229 SUPERFAMILY SSF51735 4 229 3.44E-55 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38100 24ff57a9627c03bccd1ad440a5382b21 229 PANTHER PTHR24322 151 182 2.1E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38100 24ff57a9627c03bccd1ad440a5382b21 229 PANTHER PTHR24322 8 133 2.1E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38100 24ff57a9627c03bccd1ad440a5382b21 229 Pfam PF00106 short chain dehydrogenase 5 189 6.9E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38100 24ff57a9627c03bccd1ad440a5382b21 229 Gene3D G3DSA:3.40.50.720 4 229 5.2E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32125 be7d14aed233e24bcb033d4c27012bda 181 PANTHER PTHR14359 16 166 6.6E-21 T 23-04-2016 DC74_RS32125 be7d14aed233e24bcb033d4c27012bda 181 PANTHER PTHR14359:SF20 16 166 6.6E-21 T 23-04-2016 DC74_RS32125 be7d14aed233e24bcb033d4c27012bda 181 Gene3D G3DSA:3.40.50.1950 16 171 1.1E-32 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS32125 be7d14aed233e24bcb033d4c27012bda 181 SUPERFAMILY SSF52507 16 166 2.88E-33 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS32125 be7d14aed233e24bcb033d4c27012bda 181 Pfam PF02441 Flavoprotein 16 137 1.5E-21 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS04170 7d2d774ea5e77059f545417609b1d4bd 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 2 119 17.999 T 23-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 DC74_RS04170 7d2d774ea5e77059f545417609b1d4bd 127 TIGRFAM TIGR00494 crcB: protein CrcB 4 116 7.9E-25 T 23-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 DC74_RS04170 7d2d774ea5e77059f545417609b1d4bd 127 PANTHER PTHR28259 4 127 1.7E-34 T 23-04-2016 DC74_RS04170 7d2d774ea5e77059f545417609b1d4bd 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 113 5.8E-21 T 23-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 DC74_RS18310 a604c6e1fa07a5784f80107daa9ac50b 424 SUPERFAMILY SSF47203 261 395 3.89E-31 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS18310 a604c6e1fa07a5784f80107daa9ac50b 424 PANTHER PTHR10909 1 396 2.0E-73 T 23-04-2016 DC74_RS18310 a604c6e1fa07a5784f80107daa9ac50b 424 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 6.1E-22 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS18310 a604c6e1fa07a5784f80107daa9ac50b 424 Gene3D G3DSA:1.10.540.10 1 120 5.6E-23 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS18310 a604c6e1fa07a5784f80107daa9ac50b 424 SUPERFAMILY SSF56645 1 237 2.09E-29 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS18310 a604c6e1fa07a5784f80107daa9ac50b 424 Gene3D G3DSA:1.20.140.10 261 395 1.3E-29 T 23-04-2016 DC74_RS18310 a604c6e1fa07a5784f80107daa9ac50b 424 PANTHER PTHR10909:SF302 1 396 2.0E-73 T 23-04-2016 DC74_RS18310 a604c6e1fa07a5784f80107daa9ac50b 424 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 264 395 2.6E-23 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS10555 89ae3fad2e18fc3192576f1a4fe2167b 428 PANTHER PTHR23513:SF6 6 428 2.4E-51 T 23-04-2016 DC74_RS10555 89ae3fad2e18fc3192576f1a4fe2167b 428 Gene3D G3DSA:1.20.1250.20 224 405 4.2E-10 T 23-04-2016 DC74_RS10555 89ae3fad2e18fc3192576f1a4fe2167b 428 Gene3D G3DSA:1.20.1250.20 7 194 9.0E-13 T 23-04-2016 DC74_RS10555 89ae3fad2e18fc3192576f1a4fe2167b 428 Pfam PF05977 Transmembrane secretion effector 7 410 2.0E-21 T 23-04-2016 IPR010290 Transmembrane secretion effector DC74_RS10555 89ae3fad2e18fc3192576f1a4fe2167b 428 PANTHER PTHR23513 6 428 2.4E-51 T 23-04-2016 DC74_RS10555 89ae3fad2e18fc3192576f1a4fe2167b 428 SUPERFAMILY SSF103473 6 406 4.58E-39 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21055 087d9ff6d02141affadb999fe9f572fc 204 PANTHER PTHR33169:SF4 1 184 3.5E-27 T 23-04-2016 DC74_RS21055 087d9ff6d02141affadb999fe9f572fc 204 Pfam PF10400 Virulence activator alpha C-term 90 168 1.4E-7 T 23-04-2016 IPR018309 Transcription regulator PadR, C-terminal DC74_RS21055 087d9ff6d02141affadb999fe9f572fc 204 PANTHER PTHR33169 1 184 3.5E-27 T 23-04-2016 DC74_RS21055 087d9ff6d02141affadb999fe9f572fc 204 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 3.0E-10 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS21055 087d9ff6d02141affadb999fe9f572fc 204 SUPERFAMILY SSF46785 2 169 1.71E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21055 087d9ff6d02141affadb999fe9f572fc 204 Gene3D G3DSA:1.10.10.10 1 82 9.2E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS12905 1c26a8c1cd315b3535ea181541438d2b 137 SMART SM00448 5 121 0.0071 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS12905 1c26a8c1cd315b3535ea181541438d2b 137 Gene3D G3DSA:3.40.50.2300 3 132 1.2E-13 T 23-04-2016 DC74_RS12905 1c26a8c1cd315b3535ea181541438d2b 137 SUPERFAMILY SSF52172 6 133 2.13E-11 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS29350 57e89e3c1c02eb1f573c6d5a8cdd81ca 509 PANTHER PTHR11785 20 468 6.1E-251 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS29350 57e89e3c1c02eb1f573c6d5a8cdd81ca 509 PANTHER PTHR11785:SF328 20 468 6.1E-251 T 23-04-2016 DC74_RS29350 57e89e3c1c02eb1f573c6d5a8cdd81ca 509 PIRSF PIRSF006060 19 470 9.1E-90 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS29350 57e89e3c1c02eb1f573c6d5a8cdd81ca 509 Pfam PF13520 Amino acid permease 35 435 3.6E-59 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS23465 0afc864b6571596df770b3cde06bc46b 178 Pfam PF01613 Flavin reductase like domain 23 177 1.1E-37 T 23-04-2016 IPR002563 Flavin reductase like domain GO:0010181 DC74_RS23465 0afc864b6571596df770b3cde06bc46b 178 SMART SM00903 22 176 6.6E-49 T 23-04-2016 IPR002563 Flavin reductase like domain GO:0010181 DC74_RS23465 0afc864b6571596df770b3cde06bc46b 178 PANTHER PTHR30466 8 178 2.9E-70 T 23-04-2016 DC74_RS23465 0afc864b6571596df770b3cde06bc46b 178 PANTHER PTHR30466:SF2 8 178 2.9E-70 T 23-04-2016 DC74_RS23465 0afc864b6571596df770b3cde06bc46b 178 Gene3D G3DSA:2.30.110.10 13 176 6.1E-49 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS23465 0afc864b6571596df770b3cde06bc46b 178 SUPERFAMILY SSF50475 14 177 1.03E-40 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS02725 27286710652632a2fa9db342d010ca1c 258 Gene3D G3DSA:1.10.10.10 1 71 8.2E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02725 27286710652632a2fa9db342d010ca1c 258 PANTHER PTHR30136 1 258 2.9E-55 T 23-04-2016 DC74_RS02725 27286710652632a2fa9db342d010ca1c 258 PANTHER PTHR30136:SF13 1 258 2.9E-55 T 23-04-2016 DC74_RS02725 27286710652632a2fa9db342d010ca1c 258 SUPERFAMILY SSF55781 69 247 2.94E-37 T 23-04-2016 IPR029016 GAF domain-like DC74_RS02725 27286710652632a2fa9db342d010ca1c 258 Gene3D G3DSA:3.30.450.40 72 248 6.9E-44 T 23-04-2016 IPR029016 GAF domain-like DC74_RS02725 27286710652632a2fa9db342d010ca1c 258 SUPERFAMILY SSF46785 2 76 1.37E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02725 27286710652632a2fa9db342d010ca1c 258 Pfam PF01614 Bacterial transcriptional regulator 123 244 1.6E-26 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS02725 27286710652632a2fa9db342d010ca1c 258 SMART SM00346 2 92 2.4E-26 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS02725 27286710652632a2fa9db342d010ca1c 258 Pfam PF09339 IclR helix-turn-helix domain 4 54 3.7E-15 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS26400 4662103a2451753e6e1493442af436a5 354 Gene3D G3DSA:1.10.620.20 33 321 9.8E-96 T 23-04-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 DC74_RS26400 4662103a2451753e6e1493442af436a5 354 PIRSF PIRSF000355 4 352 7.9E-99 T 23-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 DC74_RS26400 4662103a2451753e6e1493442af436a5 354 SUPERFAMILY SSF47240 24 341 1.33E-87 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS26400 4662103a2451753e6e1493442af436a5 354 PANTHER PTHR23409:SF18 33 354 1.1E-117 T 23-04-2016 DC74_RS26400 4662103a2451753e6e1493442af436a5 354 PANTHER PTHR23409 33 354 1.1E-117 T 23-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 DC74_RS26400 4662103a2451753e6e1493442af436a5 354 Pfam PF00268 Ribonucleotide reductase, small chain 33 317 4.1E-79 T 23-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 DC74_RS33490 cb4e3fc7491b97ae518f5de46491cfde 465 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 261 272 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS33490 cb4e3fc7491b97ae518f5de46491cfde 465 PANTHER PTHR11699:SF28 3 460 2.8E-255 T 23-04-2016 DC74_RS33490 cb4e3fc7491b97ae518f5de46491cfde 465 PANTHER PTHR11699 3 460 2.8E-255 T 23-04-2016 DC74_RS33490 cb4e3fc7491b97ae518f5de46491cfde 465 Gene3D G3DSA:3.40.309.10 248 434 1.8E-65 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS33490 cb4e3fc7491b97ae518f5de46491cfde 465 Pfam PF00171 Aldehyde dehydrogenase family 3 459 2.0E-142 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS33490 cb4e3fc7491b97ae518f5de46491cfde 465 SUPERFAMILY SSF53720 3 462 2.09E-146 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS33490 cb4e3fc7491b97ae518f5de46491cfde 465 Gene3D G3DSA:3.40.605.10 3 247 2.4E-73 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS13825 ce0d9493d2b943d7204f822a1b8eb0ac 306 Gene3D G3DSA:3.40.50.620 149 292 3.9E-20 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS13825 ce0d9493d2b943d7204f822a1b8eb0ac 306 PANTHER PTHR31964 6 151 2.8E-21 T 23-04-2016 DC74_RS13825 ce0d9493d2b943d7204f822a1b8eb0ac 306 SUPERFAMILY SSF52402 153 293 9.21E-20 T 23-04-2016 DC74_RS13825 ce0d9493d2b943d7204f822a1b8eb0ac 306 Gene3D G3DSA:3.40.50.620 4 134 4.7E-26 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS13825 ce0d9493d2b943d7204f822a1b8eb0ac 306 PRINTS PR01438 Universal stress protein signature 3 21 1.2E-11 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS13825 ce0d9493d2b943d7204f822a1b8eb0ac 306 PRINTS PR01438 Universal stress protein signature 109 131 1.2E-11 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS13825 ce0d9493d2b943d7204f822a1b8eb0ac 306 PRINTS PR01438 Universal stress protein signature 91 103 1.2E-11 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS13825 ce0d9493d2b943d7204f822a1b8eb0ac 306 PANTHER PTHR31964:SF26 6 151 2.8E-21 T 23-04-2016 DC74_RS13825 ce0d9493d2b943d7204f822a1b8eb0ac 306 Pfam PF00582 Universal stress protein family 6 51 5.8E-10 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS13825 ce0d9493d2b943d7204f822a1b8eb0ac 306 Pfam PF00582 Universal stress protein family 95 131 2.5E-8 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS13825 ce0d9493d2b943d7204f822a1b8eb0ac 306 Pfam PF00582 Universal stress protein family 153 292 3.5E-15 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS13825 ce0d9493d2b943d7204f822a1b8eb0ac 306 SUPERFAMILY SSF52402 5 134 1.76E-24 T 23-04-2016 DC74_RS28790 05eea5a417497b0511630de75e9d1702 132 SUPERFAMILY SSF52821 8 125 6.16E-22 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS28790 05eea5a417497b0511630de75e9d1702 132 SMART SM00450 18 122 2.8E-17 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS28790 05eea5a417497b0511630de75e9d1702 132 Pfam PF00581 Rhodanese-like domain 24 118 8.1E-10 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS28790 05eea5a417497b0511630de75e9d1702 132 Gene3D G3DSA:3.40.250.10 4 124 4.0E-22 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 SUPERFAMILY SSF48150 84 292 2.51E-69 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 TIGRFAM TIGR01083 nth: endonuclease III 84 273 2.0E-74 T 23-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 SMART SM00478 117 264 1.6E-60 T 23-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 113 247 6.1E-23 T 23-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 SMART SM00525 265 285 5.4E-6 T 23-04-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 PANTHER PTHR10359 25 302 7.7E-81 T 23-04-2016 DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 PANTHER PTHR10359:SF18 25 302 7.7E-81 T 23-04-2016 DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 Gene3D G3DSA:1.10.340.30 102 201 8.7E-38 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 Hamap MF_00942 Endonuclease III [nth]. 75 288 38.045 T 23-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 ProSitePatterns PS01155 Endonuclease III family signature. 181 210 - T 23-04-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 Pfam PF00633 Helix-hairpin-helix motif 178 205 1.3E-7 T 23-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 Gene3D G3DSA:1.10.1670.10 202 287 1.5E-33 T 23-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal DC74_RS22055 d557e5dbbb96aaef29684f90278e7e17 328 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 266 282 - T 23-04-2016 IPR004035 Endonuclease III, iron-sulphur binding site DC74_RS30885 e346aed547dec1c87caf6de17ecbd428 548 SUPERFAMILY SSF56645 70 295 1.31E-31 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS30885 e346aed547dec1c87caf6de17ecbd428 548 PANTHER PTHR10909:SF289 29 459 2.9E-191 T 23-04-2016 DC74_RS30885 e346aed547dec1c87caf6de17ecbd428 548 SUPERFAMILY SSF47203 292 442 1.22E-39 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS30885 e346aed547dec1c87caf6de17ecbd428 548 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 398 417 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS30885 e346aed547dec1c87caf6de17ecbd428 548 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 286 439 1.9E-29 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS30885 e346aed547dec1c87caf6de17ecbd428 548 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 180 274 3.3E-17 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS30885 e346aed547dec1c87caf6de17ecbd428 548 Gene3D G3DSA:1.20.140.10 273 443 6.1E-40 T 23-04-2016 DC74_RS30885 e346aed547dec1c87caf6de17ecbd428 548 PANTHER PTHR10909 29 459 2.9E-191 T 23-04-2016 DC74_RS30885 e346aed547dec1c87caf6de17ecbd428 548 Gene3D G3DSA:2.40.110.10 180 272 4.3E-21 T 23-04-2016 DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 SUPERFAMILY SSF50129 50 230 2.8E-28 T 23-04-2016 IPR011032 GroES-like DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 Pfam PF00107 Zinc-binding dehydrogenase 236 380 1.1E-39 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 PANTHER PTHR11695 163 274 8.5E-96 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 PANTHER PTHR11695 54 89 8.5E-96 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 115 189 8.5E-6 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 PANTHER PTHR11695 107 145 8.5E-96 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 PANTHER PTHR11695 291 427 8.5E-96 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 PANTHER PTHR11695:SF294 163 274 8.5E-96 T 23-04-2016 DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 PANTHER PTHR11695:SF294 54 89 8.5E-96 T 23-04-2016 DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 SUPERFAMILY SSF51735 198 394 1.13E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 SMART SM00829 49 415 9.7E-12 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 Gene3D G3DSA:3.40.50.720 232 364 2.2E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 Gene3D G3DSA:3.90.180.10 44 231 7.8E-31 T 23-04-2016 IPR011032 GroES-like DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 244 7.1E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 447 458 7.1E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 328 344 7.1E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 PANTHER PTHR11695:SF294 107 145 8.5E-96 T 23-04-2016 DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 PANTHER PTHR11695:SF294 291 427 8.5E-96 T 23-04-2016 DC74_RS31775 29b53cab607c788eb69fabc8959f8ce8 458 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 31 427 8.8E-192 T 23-04-2016 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00359 B-class P450 signature 294 321 1.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00359 B-class P450 signature 277 288 1.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00359 B-class P450 signature 322 337 1.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00359 B-class P450 signature 146 162 1.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00359 B-class P450 signature 163 178 1.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00359 B-class P450 signature 343 352 1.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00359 B-class P450 signature 352 363 1.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00359 B-class P450 signature 200 222 1.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00359 B-class P450 signature 99 110 1.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 SUPERFAMILY SSF48264 4 404 5.24E-100 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00385 P450 superfamily signature 277 288 1.9E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00385 P450 superfamily signature 242 259 1.9E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00385 P450 superfamily signature 343 352 1.9E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PRINTS PR00385 P450 superfamily signature 352 363 1.9E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 Pfam PF00067 Cytochrome P450 196 374 2.2E-25 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 Gene3D G3DSA:1.10.630.10 5 405 3.5E-128 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06050 74383b13a440db0bf81b97956ab876b0 408 PANTHER PTHR11712 13 405 1.1E-94 T 23-04-2016 DC74_RS04575 9a0dd8951ac4c643f78bf3f86cd7f0ea 339 PANTHER PTHR30365:SF6 1 333 1.2E-121 T 23-04-2016 DC74_RS04575 9a0dd8951ac4c643f78bf3f86cd7f0ea 339 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 5.7E-107 T 23-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 DC74_RS04575 9a0dd8951ac4c643f78bf3f86cd7f0ea 339 PANTHER PTHR30365 1 333 1.2E-121 T 23-04-2016 DC74_RS04575 9a0dd8951ac4c643f78bf3f86cd7f0ea 339 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 216 1.0E-70 T 23-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 DC74_RS04575 9a0dd8951ac4c643f78bf3f86cd7f0ea 339 PIRSF PIRSF000267 1 336 4.5E-116 T 23-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 SUPERFAMILY SSF55874 599 704 6.88E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 SUPERFAMILY SSF55781 201 339 2.4E-14 T 23-04-2016 IPR029016 GAF domain-like DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 384 572 3.6E-43 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 Pfam PF08447 PAS fold 61 148 7.1E-13 T 23-04-2016 IPR013655 PAS fold-3 GO:0005515 DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 SUPERFAMILY SSF81606 369 570 2.62E-10 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 Gene3D G3DSA:3.30.450.40 166 338 1.1E-13 T 23-04-2016 IPR029016 GAF domain-like DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 SUPERFAMILY SSF55785 47 152 1.92E-13 T 23-04-2016 IPR000014 PAS domain DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 SMART SM00331 358 572 2.8E-33 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 PANTHER PTHR21021:SF19 39 44 2.0E-51 T 23-04-2016 DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 PANTHER PTHR21021:SF19 333 581 2.0E-51 T 23-04-2016 DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 Pfam PF13581 Histidine kinase-like ATPase domain 591 691 4.9E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 PANTHER PTHR21021 39 44 2.0E-51 T 23-04-2016 DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 PANTHER PTHR21021 333 581 2.0E-51 T 23-04-2016 DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 Gene3D G3DSA:3.30.450.20 46 149 5.0E-15 T 23-04-2016 DC74_RS33505 815e862bcfd473cd85e4adf73141840d 715 SMART SM00065 183 337 0.0016 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PANTHER PTHR10169 13 684 1.8E-289 T 23-04-2016 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 41 684 4.2E-284 T 23-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 Gene3D G3DSA:3.30.230.10 262 437 1.7E-71 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 38 684 88.438 T 23-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 Pfam PF01751 Toprim domain 464 575 2.9E-17 T 23-04-2016 IPR006171 Toprim domain DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 SMART SM00387 66 210 5.3E-19 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 Pfam PF00204 DNA gyrase B 263 435 1.7E-62 T 23-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 Gene3D G3DSA:3.30.565.10 41 246 5.9E-87 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR01159 DNA gyrase subunit B signature 262 284 3.5E-74 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR01159 DNA gyrase subunit B signature 637 649 3.5E-74 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR01159 DNA gyrase subunit B signature 215 230 3.5E-74 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR01159 DNA gyrase subunit B signature 405 419 3.5E-74 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR01159 DNA gyrase subunit B signature 230 243 3.5E-74 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR01159 DNA gyrase subunit B signature 287 305 3.5E-74 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR01159 DNA gyrase subunit B signature 419 439 3.5E-74 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR01159 DNA gyrase subunit B signature 653 669 3.5E-74 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR01159 DNA gyrase subunit B signature 41 51 3.5E-74 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR01159 DNA gyrase subunit B signature 357 373 3.5E-74 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR01159 DNA gyrase subunit B signature 515 524 3.5E-74 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 SMART SM00433 70 677 0.0 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 SUPERFAMILY SSF55874 41 247 3.41E-69 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 SUPERFAMILY SSF56719 439 679 1.05E-82 T 23-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 SUPERFAMILY SSF54211 263 436 1.48E-55 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 Gene3D G3DSA:3.40.50.670 449 666 3.0E-88 T 23-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 615 673 4.7E-24 T 23-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 ProSitePatterns PS00177 DNA topoisomerase II signature. 467 475 - T 23-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 68 208 4.9E-21 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR00418 DNA topoisomerase II family signature 313 326 6.0E-66 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR00418 DNA topoisomerase II family signature 105 118 6.0E-66 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR00418 DNA topoisomerase II family signature 569 581 6.0E-66 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR00418 DNA topoisomerase II family signature 616 632 6.0E-66 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR00418 DNA topoisomerase II family signature 70 85 6.0E-66 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR00418 DNA topoisomerase II family signature 465 479 6.0E-66 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR00418 DNA topoisomerase II family signature 531 547 6.0E-66 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR00418 DNA topoisomerase II family signature 549 566 6.0E-66 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20665 387b9d281e9eebbdd0c9fa8d862f2204 684 PRINTS PR00418 DNA topoisomerase II family signature 148 162 6.0E-66 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS01380 61d69d89a7b8d9482333ffbff5502c2e 379 Pfam PF06081 Aromatic acid exporter family member 1 27 159 5.9E-5 T 23-04-2016 IPR010343 Aromatic acid exporter family member 1 DC74_RS20790 7351ab3de62b95346b733f95d46a713a 222 Pfam PF03551 Transcriptional regulator PadR-like family 12 94 2.6E-15 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS20790 7351ab3de62b95346b733f95d46a713a 222 SUPERFAMILY SSF46785 8 184 2.65E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20790 7351ab3de62b95346b733f95d46a713a 222 PANTHER PTHR33169 4 200 5.8E-75 T 23-04-2016 DC74_RS20790 7351ab3de62b95346b733f95d46a713a 222 Gene3D G3DSA:1.10.10.10 4 99 6.2E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20790 7351ab3de62b95346b733f95d46a713a 222 PANTHER PTHR33169:SF11 4 200 5.8E-75 T 23-04-2016 DC74_RS37235 e4bd568c4b57ae9ea9821166fd6c2367 207 SUPERFAMILY SSF46689 2 71 1.23E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS37235 e4bd568c4b57ae9ea9821166fd6c2367 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 9.1E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37235 e4bd568c4b57ae9ea9821166fd6c2367 207 PANTHER PTHR30328:SF29 5 185 1.2E-33 T 23-04-2016 DC74_RS37235 e4bd568c4b57ae9ea9821166fd6c2367 207 SUPERFAMILY SSF48498 78 203 2.57E-24 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS37235 e4bd568c4b57ae9ea9821166fd6c2367 207 PANTHER PTHR30328 5 185 1.2E-33 T 23-04-2016 DC74_RS37235 e4bd568c4b57ae9ea9821166fd6c2367 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS37235 e4bd568c4b57ae9ea9821166fd6c2367 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.4E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37235 e4bd568c4b57ae9ea9821166fd6c2367 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.4E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37235 e4bd568c4b57ae9ea9821166fd6c2367 207 Gene3D G3DSA:1.10.357.10 1 191 1.4E-36 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 SUPERFAMILY SSF53732 1 467 3.14E-159 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 Gene3D G3DSA:3.30.499.10 330 467 1.7E-56 T 23-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 467 57.173 T 23-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PANTHER PTHR11670 329 462 2.9E-242 T 23-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PANTHER PTHR11670 4 309 2.9E-242 T 23-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PRINTS PR00415 Aconitase family signature 135 150 3.62E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PRINTS PR00415 Aconitase family signature 401 414 3.62E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PRINTS PR00415 Aconitase family signature 197 210 3.62E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PRINTS PR00415 Aconitase family signature 110 118 3.62E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PRINTS PR00415 Aconitase family signature 288 302 3.62E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PRINTS PR00415 Aconitase family signature 345 356 3.62E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PRINTS PR00415 Aconitase family signature 121 134 3.62E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PRINTS PR00415 Aconitase family signature 84 97 3.62E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PRINTS PR00415 Aconitase family signature 211 224 3.62E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PANTHER PTHR11670:SF38 329 462 2.9E-242 T 23-04-2016 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 PANTHER PTHR11670:SF38 4 309 2.9E-242 T 23-04-2016 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 Gene3D G3DSA:3.40.1060.10 168 283 4.9E-37 T 23-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 Gene3D G3DSA:3.30.499.10 2 160 2.5E-24 T 23-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 ProSitePatterns PS01244 Aconitase family signature 2. 401 414 - T 23-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 2 462 1.8E-215 T 23-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 Pfam PF00330 Aconitase family (aconitate hydratase) 7 459 9.9E-153 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37295 73d2ee8c0aa859f5cde4025994d421ff 467 ProSitePatterns PS00450 Aconitase family signature 1. 341 357 - T 23-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS18670 7c2294baed4fcd384646860fc3c5ef7e 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.492 T 23-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 DC74_RS18670 7c2294baed4fcd384646860fc3c5ef7e 132 Gene3D G3DSA:3.30.1370.30 2 72 8.8E-28 T 23-04-2016 DC74_RS18670 7c2294baed4fcd384646860fc3c5ef7e 132 PANTHER PTHR11758 1 132 1.5E-55 T 23-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 DC74_RS18670 7c2294baed4fcd384646860fc3c5ef7e 132 SUPERFAMILY SSF56047 3 132 7.72E-44 T 23-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 DC74_RS18670 7c2294baed4fcd384646860fc3c5ef7e 132 Pfam PF00410 Ribosomal protein S8 5 132 4.1E-49 T 23-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 DC74_RS18670 7c2294baed4fcd384646860fc3c5ef7e 132 Gene3D G3DSA:3.30.1490.10 76 132 6.2E-28 T 23-04-2016 DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 Gene3D G3DSA:3.40.50.920 501 620 1.2E-31 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 1.1E-107 T 23-04-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 23-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 PANTHER PTHR11624 17 211 7.9E-261 T 23-04-2016 IPR033247 Transketolase family DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 23-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 SUPERFAMILY SSF52922 501 620 4.19E-28 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 SUPERFAMILY SSF52518 294 477 9.64E-51 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 PANTHER PTHR11624:SF20 238 633 7.9E-261 T 23-04-2016 DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 PANTHER PTHR11624:SF20 17 211 7.9E-261 T 23-04-2016 DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 SUPERFAMILY SSF52518 3 345 3.54E-69 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 622 41.661 T 23-04-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 Gene3D G3DSA:3.40.50.970 331 479 1.0E-29 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 SMART SM00861 315 479 3.2E-50 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 Pfam PF02780 Transketolase, C-terminal domain 501 613 4.8E-29 T 23-04-2016 IPR033248 Transketolase, C-terminal domain DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 PANTHER PTHR11624 238 633 7.9E-261 T 23-04-2016 IPR033247 Transketolase family DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 Pfam PF02779 Transketolase, pyrimidine binding domain 316 477 7.7E-37 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 5 618 1.3E-191 T 23-04-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 Gene3D G3DSA:3.40.50.970 239 330 7.8E-59 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS29750 0880e3ff5a4e20d733cb0d37e3ad2d42 655 Gene3D G3DSA:3.40.50.970 18 194 7.8E-59 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS17310 eccf1eb5629dc36c4fced140e8087afb 951 Gene3D G3DSA:3.90.550.10 4 208 8.3E-49 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS17310 eccf1eb5629dc36c4fced140e8087afb 951 SUPERFAMILY SSF53448 4 242 1.22E-49 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS17310 eccf1eb5629dc36c4fced140e8087afb 951 Pfam PF00535 Glycosyl transferase family 2 7 147 6.8E-32 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS17310 eccf1eb5629dc36c4fced140e8087afb 951 PANTHER PTHR37316 582 951 9.7E-52 T 23-04-2016 DC74_RS17310 eccf1eb5629dc36c4fced140e8087afb 951 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 577 945 1.4E-97 T 23-04-2016 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 DC74_RS17310 eccf1eb5629dc36c4fced140e8087afb 951 SUPERFAMILY SSF53756 708 945 1.16E-12 T 23-04-2016 DC74_RS13920 d90b38fa62771c258aa1d7d418f4f093 368 PANTHER PTHR32097 1 254 1.0E-66 T 23-04-2016 DC74_RS13920 d90b38fa62771c258aa1d7d418f4f093 368 Gene3D G3DSA:2.60.60.30 16 171 2.0E-27 T 23-04-2016 DC74_RS13920 d90b38fa62771c258aa1d7d418f4f093 368 PANTHER PTHR32097:SF4 1 254 1.0E-66 T 23-04-2016 DC74_RS13920 d90b38fa62771c258aa1d7d418f4f093 368 Pfam PF02342 TerD domain 1 174 1.5E-42 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS08035 e701b94317e7979bd850e9473a9c6638 142 Gene3D G3DSA:3.30.530.20 1 141 5.2E-19 T 23-04-2016 IPR023393 START-like domain DC74_RS08035 e701b94317e7979bd850e9473a9c6638 142 SUPERFAMILY SSF55961 1 141 2.0E-24 T 23-04-2016 DC74_RS08035 e701b94317e7979bd850e9473a9c6638 142 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 138 2.5E-20 T 23-04-2016 IPR019587 Polyketide cyclase/dehydrase DC74_RS37445 ae46628a12898a1b982f2fbc227da3af 212 PANTHER PTHR30055 1 200 1.4E-18 T 23-04-2016 DC74_RS37445 ae46628a12898a1b982f2fbc227da3af 212 Gene3D G3DSA:1.10.357.10 8 205 6.4E-29 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS37445 ae46628a12898a1b982f2fbc227da3af 212 SUPERFAMILY SSF46689 5 79 5.64E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS37445 ae46628a12898a1b982f2fbc227da3af 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.9E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37445 ae46628a12898a1b982f2fbc227da3af 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.9E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37445 ae46628a12898a1b982f2fbc227da3af 212 PANTHER PTHR30055:SF73 1 200 1.4E-18 T 23-04-2016 DC74_RS37445 ae46628a12898a1b982f2fbc227da3af 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 3.5E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37445 ae46628a12898a1b982f2fbc227da3af 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 SUPERFAMILY SSF51294 1040 1183 6.8E-16 T 23-04-2016 IPR028992 Hedgehog/Intein (Hint) domain DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 SMART SM00306 1037 1141 4.4E-9 T 23-04-2016 IPR003587 Hint domain N-terminal DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 Gene3D G3DSA:2.170.16.10 1037 1226 4.7E-23 T 23-04-2016 IPR028992 Hedgehog/Intein (Hint) domain DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 PANTHER PTHR23242:SF9 1 918 5.8E-40 T 23-04-2016 DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 Pfam PF07591 Pretoxin HINT domain 1054 1185 6.7E-17 T 23-04-2016 DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 Pfam PF03752 Short repeats of unknown function 166 206 1.4E-15 T 23-04-2016 IPR005506 Protein of unknown function DUF312 DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 Pfam PF03752 Short repeats of unknown function 580 620 2.4E-9 T 23-04-2016 IPR005506 Protein of unknown function DUF312 DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 Pfam PF03752 Short repeats of unknown function 673 713 1.5E-17 T 23-04-2016 IPR005506 Protein of unknown function DUF312 DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 Pfam PF03752 Short repeats of unknown function 30 62 3.8E-6 T 23-04-2016 IPR005506 Protein of unknown function DUF312 DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 Pfam PF03752 Short repeats of unknown function 121 160 2.6E-13 T 23-04-2016 IPR005506 Protein of unknown function DUF312 DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 Pfam PF03752 Short repeats of unknown function 719 759 1.3E-8 T 23-04-2016 IPR005506 Protein of unknown function DUF312 DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 Pfam PF03752 Short repeats of unknown function 74 113 8.8E-10 T 23-04-2016 IPR005506 Protein of unknown function DUF312 DC74_RS30035 cdadb974209032352ffc5e7bd5f5de54 1279 PANTHER PTHR23242 1 918 5.8E-40 T 23-04-2016 DC74_RS33735 9e7ac88567dd1720f4156d70023678c9 115 SUPERFAMILY SSF56112 5 108 3.06E-9 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS33735 9e7ac88567dd1720f4156d70023678c9 115 Gene3D G3DSA:3.90.1200.10 5 112 9.4E-8 T 23-04-2016 DC74_RS33735 9e7ac88567dd1720f4156d70023678c9 115 Pfam PF01636 Phosphotransferase enzyme family 5 54 3.5E-5 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS25925 21a45416d4a6b0896a1c0eb79ce07dae 375 PANTHER PTHR11751:SF354 24 373 9.5E-131 T 23-04-2016 DC74_RS25925 21a45416d4a6b0896a1c0eb79ce07dae 375 Pfam PF00155 Aminotransferase class I and II 40 373 3.0E-42 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS25925 21a45416d4a6b0896a1c0eb79ce07dae 375 PANTHER PTHR11751 24 373 9.5E-131 T 23-04-2016 DC74_RS25925 21a45416d4a6b0896a1c0eb79ce07dae 375 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 18 373 8.0E-183 T 23-04-2016 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria DC74_RS25925 21a45416d4a6b0896a1c0eb79ce07dae 375 Gene3D G3DSA:3.40.640.10 53 251 6.7E-40 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS25925 21a45416d4a6b0896a1c0eb79ce07dae 375 SUPERFAMILY SSF53383 16 374 4.31E-78 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS25925 21a45416d4a6b0896a1c0eb79ce07dae 375 Gene3D G3DSA:3.90.1150.10 252 374 5.3E-22 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS16650 67a942143a5969e4f322e99078fcdadd 634 SUPERFAMILY SSF52402 461 577 1.41E-20 T 23-04-2016 DC74_RS16650 67a942143a5969e4f322e99078fcdadd 634 SUPERFAMILY SSF52402 202 361 1.41E-20 T 23-04-2016 DC74_RS16650 67a942143a5969e4f322e99078fcdadd 634 Pfam PF00733 Asparagine synthase 220 589 1.2E-29 T 23-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 DC74_RS16650 67a942143a5969e4f322e99078fcdadd 634 Gene3D G3DSA:3.60.20.10 153 206 4.7E-4 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS16650 67a942143a5969e4f322e99078fcdadd 634 Gene3D G3DSA:3.40.50.620 207 363 1.9E-23 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS16650 67a942143a5969e4f322e99078fcdadd 634 Gene3D G3DSA:3.40.50.620 460 585 1.9E-23 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS13020 facdefafa1d8b6ecb2f9aba66152a82d 413 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 236 410 3.1E-51 T 23-04-2016 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148|UniPathway: UPA00148 DC74_RS13020 facdefafa1d8b6ecb2f9aba66152a82d 413 Gene3D G3DSA:3.60.15.10 3 75 3.1E-9 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS13020 facdefafa1d8b6ecb2f9aba66152a82d 413 PANTHER PTHR34848 224 413 8.3E-68 T 23-04-2016 DC74_RS13020 facdefafa1d8b6ecb2f9aba66152a82d 413 Gene3D G3DSA:3.40.50.300 236 411 1.5E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS13020 facdefafa1d8b6ecb2f9aba66152a82d 413 SUPERFAMILY SSF56281 2 137 9.47E-6 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS13020 facdefafa1d8b6ecb2f9aba66152a82d 413 SUPERFAMILY SSF52540 236 411 8.9E-37 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00955 90e8871707aadecb7a3f00b09988bb8c 129 SUPERFAMILY SSF46785 12 115 1.39E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00955 90e8871707aadecb7a3f00b09988bb8c 129 Pfam PF01638 HxlR-like helix-turn-helix 22 109 1.1E-26 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS00955 90e8871707aadecb7a3f00b09988bb8c 129 PANTHER PTHR33204 1 120 6.3E-35 T 23-04-2016 DC74_RS00955 90e8871707aadecb7a3f00b09988bb8c 129 Gene3D G3DSA:1.10.10.10 9 116 5.0E-38 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29865 b5e1c7dce4e92699871b946b569bf103 361 PANTHER PTHR12169:SF0 98 357 4.3E-74 T 23-04-2016 DC74_RS29865 b5e1c7dce4e92699871b946b569bf103 361 Gene3D G3DSA:3.40.50.300 27 222 2.9E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29865 b5e1c7dce4e92699871b946b569bf103 361 SUPERFAMILY SSF52540 95 266 2.83E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29865 b5e1c7dce4e92699871b946b569bf103 361 PANTHER PTHR12169 98 357 4.3E-74 T 23-04-2016 IPR005654 ATPase, AFG1-like GO:0005524 DC74_RS29865 b5e1c7dce4e92699871b946b569bf103 361 Pfam PF03969 AFG1-like ATPase 54 246 2.7E-40 T 23-04-2016 IPR005654 ATPase, AFG1-like GO:0005524 DC74_RS29865 b5e1c7dce4e92699871b946b569bf103 361 Pfam PF03969 AFG1-like ATPase 248 353 4.6E-15 T 23-04-2016 IPR005654 ATPase, AFG1-like GO:0005524 DC74_RS20740 0c33720d7cd34698be1eed140ecb15ee 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 23-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 DC74_RS20740 0c33720d7cd34698be1eed140ecb15ee 108 SUPERFAMILY SSF52833 4 107 3.28E-37 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS20740 0c33720d7cd34698be1eed140ecb15ee 108 PANTHER PTHR10438 9 108 4.0E-39 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DC74_RS20740 0c33720d7cd34698be1eed140ecb15ee 108 PIRSF PIRSF000077 2 107 4.8E-40 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DC74_RS20740 0c33720d7cd34698be1eed140ecb15ee 108 PRINTS PR00421 Thioredoxin family signature 24 32 1.5E-7 T 23-04-2016 DC74_RS20740 0c33720d7cd34698be1eed140ecb15ee 108 PRINTS PR00421 Thioredoxin family signature 71 82 1.5E-7 T 23-04-2016 DC74_RS20740 0c33720d7cd34698be1eed140ecb15ee 108 PRINTS PR00421 Thioredoxin family signature 32 41 1.5E-7 T 23-04-2016 DC74_RS20740 0c33720d7cd34698be1eed140ecb15ee 108 Pfam PF00085 Thioredoxin 6 103 5.7E-32 T 23-04-2016 IPR013766 Thioredoxin domain GO:0045454 DC74_RS20740 0c33720d7cd34698be1eed140ecb15ee 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 105 1.9E-35 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DC74_RS20740 0c33720d7cd34698be1eed140ecb15ee 108 Gene3D G3DSA:3.40.30.10 3 104 3.1E-37 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS08640 0af19851eb3b7ed2390b35804d299c26 162 PANTHER PTHR21340:SF1 122 161 6.4E-52 T 23-04-2016 DC74_RS08640 0af19851eb3b7ed2390b35804d299c26 162 PANTHER PTHR21340:SF1 4 105 6.4E-52 T 23-04-2016 DC74_RS08640 0af19851eb3b7ed2390b35804d299c26 162 SUPERFAMILY SSF55811 4 155 1.76E-16 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS08640 0af19851eb3b7ed2390b35804d299c26 162 ProSitePatterns PS00893 Nudix box signature. 45 66 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS08640 0af19851eb3b7ed2390b35804d299c26 162 PANTHER PTHR21340 122 161 6.4E-52 T 23-04-2016 DC74_RS08640 0af19851eb3b7ed2390b35804d299c26 162 PANTHER PTHR21340 4 105 6.4E-52 T 23-04-2016 DC74_RS08640 0af19851eb3b7ed2390b35804d299c26 162 Gene3D G3DSA:3.90.79.10 4 153 4.3E-26 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS08640 0af19851eb3b7ed2390b35804d299c26 162 Pfam PF00293 NUDIX domain 6 150 8.5E-13 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS28940 e92a650cf124eeadf141c52264954090 285 PANTHER PTHR10992:SF800 217 280 4.4E-46 T 23-04-2016 DC74_RS28940 e92a650cf124eeadf141c52264954090 285 PANTHER PTHR10992:SF800 8 201 4.4E-46 T 23-04-2016 DC74_RS28940 e92a650cf124eeadf141c52264954090 285 PANTHER PTHR10992 217 280 4.4E-46 T 23-04-2016 DC74_RS28940 e92a650cf124eeadf141c52264954090 285 PANTHER PTHR10992 8 201 4.4E-46 T 23-04-2016 DC74_RS28940 e92a650cf124eeadf141c52264954090 285 Gene3D G3DSA:3.40.50.1820 2 279 6.1E-49 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS28940 e92a650cf124eeadf141c52264954090 285 Pfam PF00561 alpha/beta hydrolase fold 22 265 7.7E-19 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS28940 e92a650cf124eeadf141c52264954090 285 SUPERFAMILY SSF53474 164 279 1.49E-47 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS28940 e92a650cf124eeadf141c52264954090 285 SUPERFAMILY SSF53474 3 125 1.49E-47 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 SMART SM01043 197 341 1.7E-37 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 Pfam PF00196 Bacterial regulatory proteins, luxR family 15 69 1.9E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 Pfam PF00486 Transcriptional regulatory protein, C terminal 124 190 1.2E-10 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 Pfam PF03704 Bacterial transcriptional activator domain 197 340 4.4E-34 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 SMART SM00421 12 69 5.6E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 SUPERFAMILY SSF46894 7 75 6.8E-14 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 29 45 9.1E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 15 29 9.1E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 45 57 9.1E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 Gene3D G3DSA:1.10.10.10 8 74 1.1E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 SUPERFAMILY SSF46894 102 190 9.92E-13 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 PANTHER PTHR35807 76 343 1.2E-34 T 23-04-2016 DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 SMART SM00862 115 190 5.7E-10 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 SUPERFAMILY SSF48452 193 350 1.82E-27 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS37405 98f72582c3173f8d72e98b8f9a718e62 353 Gene3D G3DSA:1.10.10.10 110 191 1.4E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13980 006592a39ad2daadeda32495c5a05bc4 292 Pfam PF09851 Short C-terminal domain 262 289 2.0E-6 T 23-04-2016 IPR018649 SHOCT domain DC74_RS13980 006592a39ad2daadeda32495c5a05bc4 292 Pfam PF14472 Domain of unknown function (DUF4429) 139 229 4.8E-39 T 23-04-2016 IPR027860 Domain of unknown function DUF4429 DC74_RS13980 006592a39ad2daadeda32495c5a05bc4 292 Pfam PF14472 Domain of unknown function (DUF4429) 12 106 3.1E-15 T 23-04-2016 IPR027860 Domain of unknown function DUF4429 DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 PIRSF PIRSF000156 6 891 0.0 T 23-04-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 Gene3D G3DSA:3.40.50.920 719 891 8.2E-65 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 Gene3D G3DSA:3.40.50.970 484 717 1.9E-111 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 Gene3D G3DSA:3.40.50.970 67 479 9.2E-133 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 148 308 4.1E-11 T 23-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 PANTHER PTHR11624:SF67 492 547 0.0 T 23-04-2016 DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 PANTHER PTHR11624:SF67 84 301 0.0 T 23-04-2016 DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 PANTHER PTHR11624:SF67 373 462 0.0 T 23-04-2016 DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 PANTHER PTHR11624:SF67 800 883 0.0 T 23-04-2016 DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 PANTHER PTHR11624:SF67 565 784 0.0 T 23-04-2016 DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 SUPERFAMILY SSF52518 67 478 2.44E-112 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 PANTHER PTHR11624 492 547 0.0 T 23-04-2016 IPR033247 Transketolase family DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 PANTHER PTHR11624 84 301 0.0 T 23-04-2016 IPR033247 Transketolase family DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 PANTHER PTHR11624 373 462 0.0 T 23-04-2016 IPR033247 Transketolase family DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 PANTHER PTHR11624 800 883 0.0 T 23-04-2016 IPR033247 Transketolase family DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 PANTHER PTHR11624 565 784 0.0 T 23-04-2016 IPR033247 Transketolase family DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 15 890 0.0 T 23-04-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 SUPERFAMILY SSF52922 714 891 8.03E-51 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 DC74_RS13065 fa4d32e1c2d1c2295d95c3eb46fa32ea 891 SUPERFAMILY SSF52518 484 713 1.83E-88 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 SMART SM00421 152 209 4.7E-24 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 SUPERFAMILY SSF46894 138 215 4.08E-22 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 Gene3D G3DSA:1.10.10.10 126 216 1.3E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 Gene3D G3DSA:3.40.50.2300 1 125 3.5E-39 T 23-04-2016 DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 Pfam PF00072 Response regulator receiver domain 5 116 7.9E-27 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 PANTHER PTHR26402 3 216 6.2E-95 T 23-04-2016 DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 3.2E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 3.2E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 3.2E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 1.3E-17 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 SMART SM00448 3 116 2.1E-30 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 SUPERFAMILY SSF52172 2 134 3.13E-34 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS32545 7fabff56438cc5f34a9a9a49da47843b 219 PANTHER PTHR26402:SF564 3 216 6.2E-95 T 23-04-2016 DC74_RS14120 a8270e1185ad1bf3344bf8132232934f 158 SUPERFAMILY SSF46785 5 139 2.77E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14120 a8270e1185ad1bf3344bf8132232934f 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 4.8E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS14120 a8270e1185ad1bf3344bf8132232934f 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 4.8E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS14120 a8270e1185ad1bf3344bf8132232934f 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 4.8E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS14120 a8270e1185ad1bf3344bf8132232934f 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 4.8E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS14120 a8270e1185ad1bf3344bf8132232934f 158 Pfam PF12802 MarR family 35 91 8.7E-14 T 23-04-2016 DC74_RS14120 a8270e1185ad1bf3344bf8132232934f 158 Gene3D G3DSA:1.10.10.10 5 139 3.8E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14120 a8270e1185ad1bf3344bf8132232934f 158 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 101 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS14120 a8270e1185ad1bf3344bf8132232934f 158 PANTHER PTHR33164 8 151 2.5E-24 T 23-04-2016 DC74_RS14120 a8270e1185ad1bf3344bf8132232934f 158 SMART SM00347 29 127 2.0E-20 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS03505 c1210d0c9280b4769f7294826b159ea5 470 SMART SM00487 46 246 5.5E-51 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS03505 c1210d0c9280b4769f7294826b159ea5 470 Gene3D G3DSA:3.40.50.300 236 387 2.1E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS03505 c1210d0c9280b4769f7294826b159ea5 470 SUPERFAMILY SSF52540 98 377 2.64E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS03505 c1210d0c9280b4769f7294826b159ea5 470 Gene3D G3DSA:3.40.50.300 26 235 2.7E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS03505 c1210d0c9280b4769f7294826b159ea5 470 PANTHER PTHR24031:SF334 19 387 2.3E-197 T 23-04-2016 DC74_RS03505 c1210d0c9280b4769f7294826b159ea5 470 Pfam PF00271 Helicase conserved C-terminal domain 263 361 2.4E-25 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS03505 c1210d0c9280b4769f7294826b159ea5 470 Pfam PF00270 DEAD/DEAH box helicase 51 219 2.8E-45 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS03505 c1210d0c9280b4769f7294826b159ea5 470 PANTHER PTHR24031 19 387 2.3E-197 T 23-04-2016 DC74_RS03505 c1210d0c9280b4769f7294826b159ea5 470 SMART SM00490 280 361 3.7E-32 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS02455 a9a84c01416a3e3076699be38db68537 460 Gene3D G3DSA:1.20.1250.20 252 436 3.0E-21 T 23-04-2016 DC74_RS02455 a9a84c01416a3e3076699be38db68537 460 PANTHER PTHR23501 6 438 4.1E-159 T 23-04-2016 DC74_RS02455 a9a84c01416a3e3076699be38db68537 460 SUPERFAMILY SSF103473 2 180 4.19E-68 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS02455 a9a84c01416a3e3076699be38db68537 460 SUPERFAMILY SSF103473 228 438 4.19E-68 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS02455 a9a84c01416a3e3076699be38db68537 460 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 1 398 4.9E-89 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS02455 a9a84c01416a3e3076699be38db68537 460 Gene3D G3DSA:1.20.1250.20 3 178 1.2E-31 T 23-04-2016 DC74_RS02455 a9a84c01416a3e3076699be38db68537 460 PANTHER PTHR23501:SF91 6 438 4.1E-159 T 23-04-2016 DC74_RS02455 a9a84c01416a3e3076699be38db68537 460 Pfam PF07690 Major Facilitator Superfamily 2 389 1.2E-58 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS20155 48ddd67fef65dfd8c95d88b0a348ee19 210 Pfam PF02570 Precorrin-8X methylmutase 13 207 9.4E-74 T 23-04-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 DC74_RS20155 48ddd67fef65dfd8c95d88b0a348ee19 210 Gene3D G3DSA:3.40.50.10230 3 206 5.7E-82 T 23-04-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 DC74_RS20155 48ddd67fef65dfd8c95d88b0a348ee19 210 SUPERFAMILY SSF63965 4 207 7.32E-75 T 23-04-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 DC74_RS20155 48ddd67fef65dfd8c95d88b0a348ee19 210 PANTHER PTHR32439 4 205 7.5E-75 T 23-04-2016 DC74_RS12535 816613d3d81845779b2c3db9da55c922 271 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 38 269 17.428 T 23-04-2016 IPR026579 Cell division protein FtsQ GO:0000917 DC74_RS12535 816613d3d81845779b2c3db9da55c922 271 PANTHER PTHR37820 35 270 2.0E-41 T 23-04-2016 DC74_RS12535 816613d3d81845779b2c3db9da55c922 271 Pfam PF08478 POTRA domain, FtsQ-type 69 137 2.1E-15 T 23-04-2016 IPR013685 Polypeptide-transport-associated, FtsQ-type DC74_RS12535 816613d3d81845779b2c3db9da55c922 271 Pfam PF03799 Cell division protein FtsQ 143 251 9.4E-6 T 23-04-2016 IPR005548 Cell division protein FtsQ/DivIB DC74_RS06345 6b9f431b2f5f9c117eb163c5eed87b4b 545 PANTHER PTHR22642 4 542 2.9E-157 T 23-04-2016 DC74_RS06345 6b9f431b2f5f9c117eb163c5eed87b4b 545 Pfam PF07969 Amidohydrolase family 50 542 4.2E-102 T 23-04-2016 IPR013108 Amidohydrolase 3 DC74_RS06345 6b9f431b2f5f9c117eb163c5eed87b4b 545 PANTHER PTHR22642:SF2 4 542 2.9E-157 T 23-04-2016 DC74_RS06345 6b9f431b2f5f9c117eb163c5eed87b4b 545 Gene3D G3DSA:2.30.40.10 488 543 2.1E-7 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS06345 6b9f431b2f5f9c117eb163c5eed87b4b 545 Gene3D G3DSA:2.30.40.10 2 86 4.3E-17 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS06345 6b9f431b2f5f9c117eb163c5eed87b4b 545 SUPERFAMILY SSF51338 3 62 4.07E-23 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS06345 6b9f431b2f5f9c117eb163c5eed87b4b 545 SUPERFAMILY SSF51338 501 543 4.07E-23 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS06345 6b9f431b2f5f9c117eb163c5eed87b4b 545 Gene3D G3DSA:3.20.20.140 199 487 7.2E-26 T 23-04-2016 DC74_RS06345 6b9f431b2f5f9c117eb163c5eed87b4b 545 SUPERFAMILY SSF51556 61 118 2.04E-30 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS06345 6b9f431b2f5f9c117eb163c5eed87b4b 545 SUPERFAMILY SSF51556 193 499 2.04E-30 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS38640 2d482bfa2aad26cfb94a7eb203428f12 163 SUPERFAMILY SSF46785 24 158 8.07E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38640 2d482bfa2aad26cfb94a7eb203428f12 163 Gene3D G3DSA:1.10.10.10 26 154 6.7E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26065 5d900e88b97bb2402310a3a036e2000e 772 SMART SM00487 29 242 5.7E-55 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS26065 5d900e88b97bb2402310a3a036e2000e 772 Pfam PF00271 Helicase conserved C-terminal domain 250 359 2.2E-27 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS26065 5d900e88b97bb2402310a3a036e2000e 772 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 170 178 - T 23-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site DC74_RS26065 5d900e88b97bb2402310a3a036e2000e 772 Pfam PF00270 DEAD/DEAH box helicase 34 210 4.2E-51 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS26065 5d900e88b97bb2402310a3a036e2000e 772 SMART SM00490 278 359 1.2E-31 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS26065 5d900e88b97bb2402310a3a036e2000e 772 PANTHER PTHR24031 10 536 1.4E-163 T 23-04-2016 DC74_RS26065 5d900e88b97bb2402310a3a036e2000e 772 PANTHER PTHR24031:SF261 10 536 1.4E-163 T 23-04-2016 DC74_RS26065 5d900e88b97bb2402310a3a036e2000e 772 SUPERFAMILY SSF52540 92 379 2.73E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26065 5d900e88b97bb2402310a3a036e2000e 772 Gene3D G3DSA:3.40.50.300 8 239 2.8E-74 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26065 5d900e88b97bb2402310a3a036e2000e 772 Gene3D G3DSA:3.40.50.300 240 391 5.7E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37700 50d262361bb60a47806ea208409f189a 389 PANTHER PTHR30605 1 373 3.3E-150 T 23-04-2016 DC74_RS37700 50d262361bb60a47806ea208409f189a 389 Pfam PF03702 Uncharacterised protein family (UPF0075) 2 367 2.8E-130 T 23-04-2016 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17|UniPathway: UPA00343|UniPathway: UPA00544 DC74_RS37700 50d262361bb60a47806ea208409f189a 389 SUPERFAMILY SSF53067 71 110 9.71E-14 T 23-04-2016 DC74_RS37700 50d262361bb60a47806ea208409f189a 389 SUPERFAMILY SSF53067 143 321 9.71E-14 T 23-04-2016 DC74_RS37700 50d262361bb60a47806ea208409f189a 389 Gene3D G3DSA:3.30.420.40 2 196 1.9E-57 T 23-04-2016 DC74_RS37700 50d262361bb60a47806ea208409f189a 389 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 368 35.233 T 23-04-2016 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17|UniPathway: UPA00343|UniPathway: UPA00544 DC74_RS37700 50d262361bb60a47806ea208409f189a 389 PANTHER PTHR30605:SF0 1 373 3.3E-150 T 23-04-2016 DC74_RS37700 50d262361bb60a47806ea208409f189a 389 Gene3D G3DSA:3.30.420.40 286 310 8.6E-4 T 23-04-2016 DC74_RS13960 8010d66bbd8bfd3f173739f4b7ed2a0c 143 Pfam PF03995 Peptidase inhibitor family I36 48 115 1.0E-11 T 23-04-2016 DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 SUPERFAMILY SSF52540 1 213 2.62E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 PRINTS PR00094 Adenylate kinase signature 81 97 2.1E-36 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 PRINTS PR00094 Adenylate kinase signature 32 46 2.1E-36 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 PRINTS PR00094 Adenylate kinase signature 178 192 2.1E-36 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 PRINTS PR00094 Adenylate kinase signature 161 176 2.1E-36 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 PRINTS PR00094 Adenylate kinase signature 4 17 2.1E-36 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 1.2E-77 T 23-04-2016 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 Hamap MF_00235 Adenylate kinase [adk]. 1 214 50.524 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 Pfam PF05191 Adenylate kinase, active site lid 127 163 2.2E-12 T 23-04-2016 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 PANTHER PTHR23359 1 213 7.8E-97 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 Gene3D G3DSA:3.40.50.300 1 212 3.8E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18635 4d49a919a226c02454a5cbaaedd4800e 217 Pfam PF00406 Adenylate kinase 5 191 1.4E-57 T 23-04-2016 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 Pfam PF00224 Pyruvate kinase, barrel domain 1 337 3.7E-126 T 23-04-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 SUPERFAMILY SSF50800 70 164 1.06E-26 T 23-04-2016 IPR011037 Pyruvate kinase-like, insert domain DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 SUPERFAMILY SSF52935 320 470 4.71E-38 T 23-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 Gene3D G3DSA:2.40.33.10 73 166 1.8E-29 T 23-04-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 PANTHER PTHR11817 1 468 1.1E-218 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 SUPERFAMILY SSF51621 1 74 1.08E-96 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 SUPERFAMILY SSF51621 154 337 1.08E-96 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 23-04-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 Gene3D G3DSA:3.40.1380.20 324 469 1.1E-42 T 23-04-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 PRINTS PR01050 Pyruvate kinase family signature 184 198 1.4E-62 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 PRINTS PR01050 Pyruvate kinase family signature 310 326 1.4E-62 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 PRINTS PR01050 Pyruvate kinase family signature 291 309 1.4E-62 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 PRINTS PR01050 Pyruvate kinase family signature 214 240 1.4E-62 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 PRINTS PR01050 Pyruvate kinase family signature 241 265 1.4E-62 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 PRINTS PR01050 Pyruvate kinase family signature 266 290 1.4E-62 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.4E-62 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 2.6E-28 T 23-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 Gene3D G3DSA:3.20.20.60 167 323 1.0E-104 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 Gene3D G3DSA:3.20.20.60 2 72 1.0E-104 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS27265 f148c741af0e6b135682b767251d74d6 475 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 6.2E-166 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 Gene3D G3DSA:3.40.50.720 1 256 5.8E-74 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 254 5.6E-51 T 23-04-2016 DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.1E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.1E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.1E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.6E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 4.6E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.6E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 4.6E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 4.6E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 4.6E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PANTHER PTHR24322 11 143 2.0E-60 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PANTHER PTHR24322 160 191 2.0E-60 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PANTHER PTHR24322:SF390 11 143 2.0E-60 T 23-04-2016 DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 PANTHER PTHR24322:SF390 160 191 2.0E-60 T 23-04-2016 DC74_RS26460 eacbb9ec3a1cdc48f72169479c290d67 257 SUPERFAMILY SSF51735 6 255 5.22E-69 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31195 068e92d85c52ca294786b07c8070322d 417 Gene3D G3DSA:3.30.1050.10 312 405 1.4E-18 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS31195 068e92d85c52ca294786b07c8070322d 417 SUPERFAMILY SSF55729 9 309 8.24E-51 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31195 068e92d85c52ca294786b07c8070322d 417 Gene3D G3DSA:3.40.630.30 6 131 9.5E-20 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31195 068e92d85c52ca294786b07c8070322d 417 PANTHER PTHR37817 1 417 2.6E-54 T 23-04-2016 DC74_RS31195 068e92d85c52ca294786b07c8070322d 417 PANTHER PTHR37817:SF1 1 417 2.6E-54 T 23-04-2016 DC74_RS31195 068e92d85c52ca294786b07c8070322d 417 Gene3D G3DSA:3.40.630.30 132 300 5.8E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31195 068e92d85c52ca294786b07c8070322d 417 Pfam PF13530 Sterol carrier protein domain 185 412 2.6E-45 T 23-04-2016 IPR025559 Enhanced intracellular survival protein domain DC74_RS31195 068e92d85c52ca294786b07c8070322d 417 SUPERFAMILY SSF55718 310 409 1.57E-19 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS31195 068e92d85c52ca294786b07c8070322d 417 Pfam PF13527 Acetyltransferase (GNAT) domain 11 134 2.6E-25 T 23-04-2016 DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 282 31.381 T 23-04-2016 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 Pfam PF01634 ATP phosphoribosyltransferase 49 203 9.3E-40 T 23-04-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 Gene3D G3DSA:3.30.70.120 210 281 3.7E-27 T 23-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 SUPERFAMILY SSF53850 1 208 5.87E-58 T 23-04-2016 DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 Pfam PF08029 HisG, C-terminal domain 207 278 4.7E-25 T 23-04-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 23-04-2016 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 191 281 1.9E-28 T 23-04-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 SUPERFAMILY SSF54913 210 281 8.34E-21 T 23-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 PANTHER PTHR21403:SF0 1 281 9.1E-99 T 23-04-2016 DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 Gene3D G3DSA:3.40.190.10 109 173 1.0E-23 T 23-04-2016 DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 4.2E-50 T 23-04-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 Gene3D G3DSA:3.40.190.10 1 108 8.4E-32 T 23-04-2016 DC74_RS09200 db27e310c9dab3fae0d5f1cbc3f851da 282 PANTHER PTHR21403 1 281 9.1E-99 T 23-04-2016 IPR001348 ATP phosphoribosyltransferase HisG GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 SUPERFAMILY SSF51735 5 250 1.51E-55 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 PANTHER PTHR24322:SF456 13 142 4.5E-60 T 23-04-2016 DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 PANTHER PTHR24322:SF456 158 190 4.5E-60 T 23-04-2016 DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 249 5.5E-43 T 23-04-2016 DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 Gene3D G3DSA:3.40.50.720 5 250 2.2E-57 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 3.2E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 3.2E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.2E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 PANTHER PTHR24322 13 142 4.5E-60 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 PANTHER PTHR24322 158 190 4.5E-60 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.0E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.0E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.0E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.0E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS02950 f28ca3b50c15b2fe858d4e16f45c4971 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.0E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS33045 cda003a39cff14cde9da9173a27d4534 164 SUPERFAMILY SSF52949 11 163 2.86E-40 T 23-04-2016 DC74_RS33045 cda003a39cff14cde9da9173a27d4534 164 PANTHER PTHR12521 10 163 1.1E-36 T 23-04-2016 DC74_RS33045 cda003a39cff14cde9da9173a27d4534 164 Pfam PF01661 Macro domain 30 146 2.1E-4 T 23-04-2016 IPR002589 Macro domain DC74_RS33045 cda003a39cff14cde9da9173a27d4534 164 SMART SM00506 10 148 6.2E-21 T 23-04-2016 IPR002589 Macro domain DC74_RS31170 12d18b9c80da21b9c3f04e83cdb5375d 487 Pfam PF00860 Permease family 47 439 3.9E-32 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS31170 12d18b9c80da21b9c3f04e83cdb5375d 487 PANTHER PTHR11119 25 467 7.7E-104 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS31170 12d18b9c80da21b9c3f04e83cdb5375d 487 PANTHER PTHR11119:SF9 25 467 7.7E-104 T 23-04-2016 IPR029940 AzgA purine transporter GO:0005345|GO:0006863 DC74_RS14175 35937dffd69862650a212f9b924eb85f 87 Pfam PF03966 Trm112p-like protein 4 43 4.3E-8 T 23-04-2016 IPR005651 Uncharacterised protein family UPF0434/Trm112 DC74_RS14175 35937dffd69862650a212f9b924eb85f 87 Gene3D G3DSA:2.20.25.10 10 66 5.1E-16 T 23-04-2016 DC74_RS14175 35937dffd69862650a212f9b924eb85f 87 PANTHER PTHR33505 4 67 2.8E-17 T 23-04-2016 DC74_RS14175 35937dffd69862650a212f9b924eb85f 87 SUPERFAMILY SSF158997 1 57 6.67E-16 T 23-04-2016 DC74_RS21895 6cc50a3b6b12ba608071f88ed21a1521 416 PANTHER PTHR21240 73 413 1.1E-18 T 23-04-2016 DC74_RS21895 6cc50a3b6b12ba608071f88ed21a1521 416 SUPERFAMILY SSF51556 16 45 1.36E-76 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS21895 6cc50a3b6b12ba608071f88ed21a1521 416 SUPERFAMILY SSF51556 95 407 1.36E-76 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS21895 6cc50a3b6b12ba608071f88ed21a1521 416 Pfam PF04909 Amidohydrolase 96 403 1.7E-49 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS21895 6cc50a3b6b12ba608071f88ed21a1521 416 Gene3D G3DSA:3.20.20.140 92 404 1.6E-71 T 23-04-2016 DC74_RS21895 6cc50a3b6b12ba608071f88ed21a1521 416 Gene3D G3DSA:3.20.20.140 17 44 1.6E-71 T 23-04-2016 DC74_RS22620 e83fd5f336bfdf294231c6f615e9870c 205 SUPERFAMILY SSF46689 5 82 4.87E-21 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS22620 e83fd5f336bfdf294231c6f615e9870c 205 PANTHER PTHR30055 1 188 2.5E-32 T 23-04-2016 DC74_RS22620 e83fd5f336bfdf294231c6f615e9870c 205 PANTHER PTHR30055:SF11 1 188 2.5E-32 T 23-04-2016 DC74_RS22620 e83fd5f336bfdf294231c6f615e9870c 205 Gene3D G3DSA:1.10.357.10 2 191 2.9E-33 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS22620 e83fd5f336bfdf294231c6f615e9870c 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 1.1E-18 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS22620 e83fd5f336bfdf294231c6f615e9870c 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.3E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS22620 e83fd5f336bfdf294231c6f615e9870c 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.3E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS22620 e83fd5f336bfdf294231c6f615e9870c 205 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS25775 8fcee55ea60b315020704e471d663d0e 469 SUPERFAMILY SSF51338 67 117 4.03E-11 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS25775 8fcee55ea60b315020704e471d663d0e 469 PANTHER PTHR11271:SF7 15 468 2.9E-81 T 23-04-2016 DC74_RS25775 8fcee55ea60b315020704e471d663d0e 469 Gene3D G3DSA:2.30.40.10 39 115 2.8E-21 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS25775 8fcee55ea60b315020704e471d663d0e 469 Gene3D G3DSA:3.20.20.140 116 379 1.2E-57 T 23-04-2016 DC74_RS25775 8fcee55ea60b315020704e471d663d0e 469 PANTHER PTHR11271 15 468 2.9E-81 T 23-04-2016 DC74_RS25775 8fcee55ea60b315020704e471d663d0e 469 SUPERFAMILY SSF51338 357 467 1.22E-25 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS25775 8fcee55ea60b315020704e471d663d0e 469 Gene3D G3DSA:2.30.40.10 380 450 1.5E-9 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS25775 8fcee55ea60b315020704e471d663d0e 469 Pfam PF01979 Amidohydrolase family 104 440 2.3E-48 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS25775 8fcee55ea60b315020704e471d663d0e 469 SUPERFAMILY SSF51556 107 393 4.66E-66 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 PANTHER PTHR11606 241 607 0.0 T 23-04-2016 DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 PANTHER PTHR11606 20 158 0.0 T 23-04-2016 DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 PANTHER PTHR11606 1167 1412 0.0 T 23-04-2016 DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 PANTHER PTHR11606 714 1142 0.0 T 23-04-2016 DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 PIRSF PIRSF036761 3 1653 0.0 T 23-04-2016 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 84 1646 0.0 T 23-04-2016 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 Gene3D G3DSA:3.40.50.720 985 1096 1.4E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 Gene3D G3DSA:3.40.50.720 1153 1225 1.4E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 SUPERFAMILY SSF51735 1128 1326 4.4E-32 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 SUPERFAMILY SSF51735 988 1090 4.4E-32 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 PANTHER PTHR11606:SF1 241 607 0.0 T 23-04-2016 DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 PANTHER PTHR11606:SF1 20 158 0.0 T 23-04-2016 DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 PANTHER PTHR11606:SF1 1167 1412 0.0 T 23-04-2016 DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 PANTHER PTHR11606:SF1 714 1142 0.0 T 23-04-2016 DC74_RS16815 0d09a225339f88753df148bec9523da6 1653 SUPERFAMILY SSF53223 797 983 2.01E-22 T 23-04-2016 DC74_RS20275 e958955998aa1bc66afd3807dc6060b3 608 SUPERFAMILY SSF56645 38 283 1.57E-41 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS20275 e958955998aa1bc66afd3807dc6060b3 608 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 1.3E-10 T 23-04-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria DC74_RS20275 e958955998aa1bc66afd3807dc6060b3 608 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 472 604 1.0E-30 T 23-04-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain DC74_RS20275 e958955998aa1bc66afd3807dc6060b3 608 Gene3D G3DSA:1.10.540.10 37 147 2.4E-6 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS20275 e958955998aa1bc66afd3807dc6060b3 608 PANTHER PTHR10909:SF340 13 482 1.8E-236 T 23-04-2016 DC74_RS20275 e958955998aa1bc66afd3807dc6060b3 608 Gene3D G3DSA:2.40.110.10 161 272 5.2E-25 T 23-04-2016 DC74_RS20275 e958955998aa1bc66afd3807dc6060b3 608 Gene3D G3DSA:1.20.140.10 273 466 5.5E-42 T 23-04-2016 DC74_RS20275 e958955998aa1bc66afd3807dc6060b3 608 PANTHER PTHR10909 13 482 1.8E-236 T 23-04-2016 DC74_RS20275 e958955998aa1bc66afd3807dc6060b3 608 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 286 452 8.8E-15 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS20275 e958955998aa1bc66afd3807dc6060b3 608 SUPERFAMILY SSF47203 290 472 3.06E-32 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS20275 e958955998aa1bc66afd3807dc6060b3 608 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 9.5E-18 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS00535 ca2c7ea40bf181d613f736e623788abe 578 SUPERFAMILY SSF75304 6 354 4.58E-79 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS00535 ca2c7ea40bf181d613f736e623788abe 578 SUPERFAMILY SSF75304 384 564 4.58E-79 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS00535 ca2c7ea40bf181d613f736e623788abe 578 Gene3D G3DSA:3.90.1300.10 6 573 1.4E-109 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS00535 ca2c7ea40bf181d613f736e623788abe 578 Pfam PF01425 Amidase 28 252 4.6E-41 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS00535 ca2c7ea40bf181d613f736e623788abe 578 Pfam PF01425 Amidase 472 553 9.5E-6 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS00535 ca2c7ea40bf181d613f736e623788abe 578 PANTHER PTHR11895 325 380 2.2E-174 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS00535 ca2c7ea40bf181d613f736e623788abe 578 PANTHER PTHR11895 415 570 2.2E-174 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS00535 ca2c7ea40bf181d613f736e623788abe 578 PANTHER PTHR11895 5 304 2.2E-174 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS00535 ca2c7ea40bf181d613f736e623788abe 578 PANTHER PTHR11895:SF94 325 380 2.2E-174 T 23-04-2016 DC74_RS00535 ca2c7ea40bf181d613f736e623788abe 578 PANTHER PTHR11895:SF94 415 570 2.2E-174 T 23-04-2016 DC74_RS00535 ca2c7ea40bf181d613f736e623788abe 578 PANTHER PTHR11895:SF94 5 304 2.2E-174 T 23-04-2016 DC74_RS08400 0ca8bb219e04a92dfa9a8d5ef7bec8b1 542 Gene3D G3DSA:3.40.50.980 4 183 1.1E-36 T 23-04-2016 DC74_RS08400 0ca8bb219e04a92dfa9a8d5ef7bec8b1 542 Gene3D G3DSA:3.30.300.30 438 534 9.1E-30 T 23-04-2016 DC74_RS08400 0ca8bb219e04a92dfa9a8d5ef7bec8b1 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 450 526 9.0E-19 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS08400 0ca8bb219e04a92dfa9a8d5ef7bec8b1 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS08400 0ca8bb219e04a92dfa9a8d5ef7bec8b1 542 Pfam PF00501 AMP-binding enzyme 11 440 2.2E-64 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS08400 0ca8bb219e04a92dfa9a8d5ef7bec8b1 542 Gene3D G3DSA:3.40.50.980 184 350 1.3E-21 T 23-04-2016 DC74_RS08400 0ca8bb219e04a92dfa9a8d5ef7bec8b1 542 SUPERFAMILY SSF56801 4 539 1.83E-118 T 23-04-2016 DC74_RS08400 0ca8bb219e04a92dfa9a8d5ef7bec8b1 542 PANTHER PTHR24095 7 155 2.2E-96 T 23-04-2016 DC74_RS08400 0ca8bb219e04a92dfa9a8d5ef7bec8b1 542 PANTHER PTHR24095 171 210 2.2E-96 T 23-04-2016 DC74_RS08400 0ca8bb219e04a92dfa9a8d5ef7bec8b1 542 PANTHER PTHR24095 234 541 2.2E-96 T 23-04-2016 DC74_RS08400 0ca8bb219e04a92dfa9a8d5ef7bec8b1 542 Gene3D G3DSA:2.30.38.10 363 434 1.4E-12 T 23-04-2016 DC74_RS31810 e4cef36d5ce2abc1b25eceb0f9ed1525 339 Pfam PF04055 Radical SAM superfamily 57 228 1.2E-7 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS31810 e4cef36d5ce2abc1b25eceb0f9ed1525 339 PANTHER PTHR11228 37 312 1.6E-79 T 23-04-2016 DC74_RS31810 e4cef36d5ce2abc1b25eceb0f9ed1525 339 PANTHER PTHR11228:SF26 37 312 1.6E-79 T 23-04-2016 DC74_RS31810 e4cef36d5ce2abc1b25eceb0f9ed1525 339 Gene3D G3DSA:3.20.20.70 60 256 4.2E-4 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS31810 e4cef36d5ce2abc1b25eceb0f9ed1525 339 SUPERFAMILY SSF102114 56 263 6.47E-11 T 23-04-2016 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 468 6.3E-201 T 23-04-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 23-04-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 SMART SM01230 101 378 1.5E-153 T 23-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 256 271 - T 23-04-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 Pfam PF00120 Glutamine synthetase, catalytic domain 102 466 3.3E-138 T 23-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 94 2.7E-24 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 385 397 - T 23-04-2016 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 PANTHER PTHR20852 1 137 2.1E-258 T 23-04-2016 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 PANTHER PTHR20852 155 469 2.1E-258 T 23-04-2016 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 Gene3D G3DSA:3.30.590.10 105 448 8.3E-137 T 23-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 SUPERFAMILY SSF55931 102 468 1.08E-137 T 23-04-2016 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 PANTHER PTHR20852:SF15 1 137 2.1E-258 T 23-04-2016 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 PANTHER PTHR20852:SF15 155 469 2.1E-258 T 23-04-2016 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 SUPERFAMILY SSF54368 5 99 2.09E-29 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13130 d89f592c3b49461c65b94cd25c5ca8a7 469 Gene3D G3DSA:3.10.20.70 5 104 2.0E-33 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS18810 51cebaf7968d4e453a7c6288fe08f582 98 PANTHER PTHR33910 17 98 4.6E-17 T 23-04-2016 DC74_RS18810 51cebaf7968d4e453a7c6288fe08f582 98 PANTHER PTHR33910:SF1 17 98 4.6E-17 T 23-04-2016 DC74_RS18810 51cebaf7968d4e453a7c6288fe08f582 98 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 44 98 1.0E-19 T 23-04-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 DC74_RS18810 51cebaf7968d4e453a7c6288fe08f582 98 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 45 94 7.0E-18 T 23-04-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 DC74_RS18810 51cebaf7968d4e453a7c6288fe08f582 98 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 45 73 - T 23-04-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 DC74_RS18810 51cebaf7968d4e453a7c6288fe08f582 98 Gene3D G3DSA:1.20.5.1030 39 97 4.3E-21 T 23-04-2016 DC74_RS18810 51cebaf7968d4e453a7c6288fe08f582 98 Hamap MF_00422 Protein translocase subunit SecE [secE]. 40 95 13.61 T 23-04-2016 IPR022943 Preprotein translocase subunit SecE DC74_RS01685 3d75b0075d1be9908a51955134db7909 143 Gene3D G3DSA:2.30.110.10 4 141 4.6E-33 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS01685 3d75b0075d1be9908a51955134db7909 143 TIGRFAM TIGR03668 Rv0121_F420: PPOX class probable F420-dependent enzyme, Rv0121 family 8 141 5.6E-49 T 23-04-2016 IPR019967 F420-dependent enzyme, PPOX class, family Rv0121, probable DC74_RS01685 3d75b0075d1be9908a51955134db7909 143 SUPERFAMILY SSF50475 3 141 1.7E-24 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS01685 3d75b0075d1be9908a51955134db7909 143 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 98 1.9E-14 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 SUPERFAMILY SSF53623 168 411 1.02E-63 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 Gene3D G3DSA:3.90.190.20 416 563 3.9E-49 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 PANTHER PTHR23135:SF4 76 583 2.5E-176 T 23-04-2016 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 SUPERFAMILY SSF53244 412 571 1.57E-43 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 Pfam PF01225 Mur ligase family, catalytic domain 89 161 1.0E-11 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 Gene3D G3DSA:3.40.1190.10 170 415 4.8E-74 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 67 569 32.828 T 23-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 Pfam PF02875 Mur ligase family, glutamate ligase domain 412 496 3.1E-18 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 PANTHER PTHR23135 76 583 2.5E-176 T 23-04-2016 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 Pfam PF08245 Mur ligase middle domain 177 391 1.3E-47 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 Gene3D G3DSA:3.40.1390.10 72 166 8.1E-22 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 SUPERFAMILY SSF63418 79 166 6.41E-20 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12565 f464ffb24e634450252dcf2a62573a79 588 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 87 568 1.0E-136 T 23-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 DC74_RS06220 7a65d954a91b8b93862f276a54801215 150 PANTHER PTHR11079 2 150 2.6E-28 T 23-04-2016 DC74_RS06220 7a65d954a91b8b93862f276a54801215 150 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 48 85 - T 23-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 DC74_RS06220 7a65d954a91b8b93862f276a54801215 150 PANTHER PTHR11079:SF69 2 150 2.6E-28 T 23-04-2016 DC74_RS06220 7a65d954a91b8b93862f276a54801215 150 SUPERFAMILY SSF53927 2 149 1.95E-32 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS06220 7a65d954a91b8b93862f276a54801215 150 Gene3D G3DSA:3.40.140.10 2 149 5.4E-35 T 23-04-2016 DC74_RS06220 7a65d954a91b8b93862f276a54801215 150 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 96 3.3E-16 T 23-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 DC74_RS06305 1f3eb600f2cd832e3d5f3b8d8c253e7d 162 Pfam PF00583 Acetyltransferase (GNAT) family 66 136 1.5E-16 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS06305 1f3eb600f2cd832e3d5f3b8d8c253e7d 162 PANTHER PTHR23091 1 157 2.5E-22 T 23-04-2016 DC74_RS06305 1f3eb600f2cd832e3d5f3b8d8c253e7d 162 SUPERFAMILY SSF55729 2 147 1.26E-32 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06305 1f3eb600f2cd832e3d5f3b8d8c253e7d 162 Gene3D G3DSA:3.40.630.30 3 158 4.1E-32 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 PANTHER PTHR11575 47 592 2.1E-173 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 Gene3D G3DSA:3.90.780.10 382 592 4.4E-40 T 23-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 SUPERFAMILY SSF56300 51 380 1.52E-74 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 PANTHER PTHR11575:SF6 47 592 2.1E-173 T 23-04-2016 DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 PRINTS PR01607 Apyrase family signature 251 268 2.3E-22 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 PRINTS PR01607 Apyrase family signature 536 555 2.3E-22 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 PRINTS PR01607 Apyrase family signature 317 337 2.3E-22 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 PRINTS PR01607 Apyrase family signature 445 468 2.3E-22 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 PRINTS PR01607 Apyrase family signature 52 70 2.3E-22 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 PRINTS PR01607 Apyrase family signature 284 307 2.3E-22 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 Gene3D G3DSA:3.60.21.10 52 380 5.8E-77 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 Pfam PF00149 Calcineurin-like phosphoesterase 54 301 7.6E-10 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 ProSitePatterns PS00786 5'-nucleotidase signature 2. 149 160 - T 23-04-2016 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 SUPERFAMILY SSF55816 379 592 7.46E-40 T 23-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 DC74_RS12140 8435b03486ef1a9bfe7bf6e9bca1eb74 608 Pfam PF02872 5'-nucleotidase, C-terminal domain 382 561 3.7E-28 T 23-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 DC74_RS39080 5ddaa13cec124a67d3f2bd3422038c0b 558 SMART SM00997 318 478 1.3E-4 T 23-04-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS39080 5ddaa13cec124a67d3f2bd3422038c0b 558 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 338 473 1.2E-8 T 23-04-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS39080 5ddaa13cec124a67d3f2bd3422038c0b 558 Gene3D G3DSA:3.40.50.720 356 396 1.3E-4 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39080 5ddaa13cec124a67d3f2bd3422038c0b 558 SUPERFAMILY SSF51735 331 447 9.67E-10 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39080 5ddaa13cec124a67d3f2bd3422038c0b 558 Gene3D G3DSA:3.40.50.1480 252 355 9.8E-9 T 23-04-2016 DC74_RS39775 fd5a4ad6972a5b4d4142e427ef4b9863 165 Gene3D G3DSA:3.40.630.30 1 164 2.2E-29 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS39775 fd5a4ad6972a5b4d4142e427ef4b9863 165 SUPERFAMILY SSF55729 1 163 1.11E-27 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS39775 fd5a4ad6972a5b4d4142e427ef4b9863 165 Pfam PF00583 Acetyltransferase (GNAT) family 73 140 1.7E-9 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS39775 fd5a4ad6972a5b4d4142e427ef4b9863 165 PANTHER PTHR23091 1 144 2.9E-14 T 23-04-2016 DC74_RS10100 6a3a33f644074f74efaa50b2e56c3773 128 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.1E-37 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 DC74_RS10100 6a3a33f644074f74efaa50b2e56c3773 128 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.1E-37 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 DC74_RS10100 6a3a33f644074f74efaa50b2e56c3773 128 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.1E-37 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 DC74_RS10100 6a3a33f644074f74efaa50b2e56c3773 128 PANTHER PTHR10986 2 124 5.8E-71 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 DC74_RS10100 6a3a33f644074f74efaa50b2e56c3773 128 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 DC74_RS10100 6a3a33f644074f74efaa50b2e56c3773 128 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 113 2.3E-44 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 DC74_RS10100 6a3a33f644074f74efaa50b2e56c3773 128 PANTHER PTHR10986:SF12 2 124 5.8E-71 T 23-04-2016 DC74_RS10100 6a3a33f644074f74efaa50b2e56c3773 128 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.627 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 DC74_RS10100 6a3a33f644074f74efaa50b2e56c3773 128 SUPERFAMILY SSF74731 3 117 3.01E-45 T 23-04-2016 DC74_RS10100 6a3a33f644074f74efaa50b2e56c3773 128 Pfam PF00453 Ribosomal protein L20 3 109 2.7E-44 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 DC74_RS10100 6a3a33f644074f74efaa50b2e56c3773 128 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 5.0E-23 T 23-04-2016 DC74_RS10100 6a3a33f644074f74efaa50b2e56c3773 128 Gene3D G3DSA:1.10.1900.20 56 117 9.3E-32 T 23-04-2016 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 337 345 - T 23-04-2016 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 ProSitePatterns PS00438 Catalase proximal active site signature. 47 63 - T 23-04-2016 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 Gene3D G3DSA:2.40.180.10 8 361 2.0E-179 T 23-04-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 PRINTS PR00067 Catalase signature 24 47 9.7E-67 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 PRINTS PR00067 Catalase signature 108 125 9.7E-67 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 PRINTS PR00067 Catalase signature 324 350 9.7E-67 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 PRINTS PR00067 Catalase signature 127 145 9.7E-67 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 PRINTS PR00067 Catalase signature 87 105 9.7E-67 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 PRINTS PR00067 Catalase signature 292 319 9.7E-67 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 PANTHER PTHR11465 10 482 6.2E-281 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 Pfam PF00199 Catalase 11 392 7.2E-186 T 23-04-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 Pfam PF06628 Catalase-related immune-responsive 421 482 4.8E-22 T 23-04-2016 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 SUPERFAMILY SSF56634 5 483 2.75E-206 T 23-04-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 PIRSF PIRSF038928 2 486 2.9E-219 T 23-04-2016 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS26315 c60b31b52165033289f3bf5bf8f11712 487 SMART SM01060 11 395 2.9E-278 T 23-04-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS22655 a58a4f27a13ff46075804ad0a2ec8003 237 Pfam PF00072 Response regulator receiver domain 6 115 3.2E-27 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS22655 a58a4f27a13ff46075804ad0a2ec8003 237 SMART SM00862 164 235 2.0E-24 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS22655 a58a4f27a13ff46075804ad0a2ec8003 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 235 1.2E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS22655 a58a4f27a13ff46075804ad0a2ec8003 237 Gene3D G3DSA:1.10.10.10 143 236 5.1E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22655 a58a4f27a13ff46075804ad0a2ec8003 237 Gene3D G3DSA:3.40.50.2300 3 126 9.9E-41 T 23-04-2016 DC74_RS22655 a58a4f27a13ff46075804ad0a2ec8003 237 SUPERFAMILY SSF52172 2 123 1.42E-39 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS22655 a58a4f27a13ff46075804ad0a2ec8003 237 SMART SM00448 4 114 1.0E-39 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS22655 a58a4f27a13ff46075804ad0a2ec8003 237 PANTHER PTHR26402 4 124 2.6E-123 T 23-04-2016 DC74_RS22655 a58a4f27a13ff46075804ad0a2ec8003 237 PANTHER PTHR26402 140 236 2.6E-123 T 23-04-2016 DC74_RS22655 a58a4f27a13ff46075804ad0a2ec8003 237 PANTHER PTHR26402:SF509 4 124 2.6E-123 T 23-04-2016 DC74_RS22655 a58a4f27a13ff46075804ad0a2ec8003 237 PANTHER PTHR26402:SF509 140 236 2.6E-123 T 23-04-2016 DC74_RS22655 a58a4f27a13ff46075804ad0a2ec8003 237 SUPERFAMILY SSF46894 141 235 7.94E-28 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS18430 98c5374c135b221214261816987f359b 415 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 196 287 5.5E-21 T 23-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 DC74_RS18430 98c5374c135b221214261816987f359b 415 PANTHER PTHR11374:SF4 3 407 1.2E-118 T 23-04-2016 DC74_RS18430 98c5374c135b221214261816987f359b 415 SMART SM00984 314 409 3.7E-18 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS18430 98c5374c135b221214261816987f359b 415 PIRSF PIRSF000124 3 414 9.5E-42 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 DC74_RS18430 98c5374c135b221214261816987f359b 415 SUPERFAMILY SSF52413 301 408 2.62E-19 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS18430 98c5374c135b221214261816987f359b 415 PANTHER PTHR11374 3 407 1.2E-118 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 DC74_RS18430 98c5374c135b221214261816987f359b 415 Gene3D G3DSA:3.40.50.720 227 407 1.1E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18430 98c5374c135b221214261816987f359b 415 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 178 1.7E-22 T 23-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS18430 98c5374c135b221214261816987f359b 415 SUPERFAMILY SSF48179 196 293 5.44E-22 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS18430 98c5374c135b221214261816987f359b 415 PIRSF PIRSF500136 1 415 1.6E-123 T 23-04-2016 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 DC74_RS18430 98c5374c135b221214261816987f359b 415 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 404 9.5E-96 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 DC74_RS18430 98c5374c135b221214261816987f359b 415 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 315 406 4.1E-14 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS18430 98c5374c135b221214261816987f359b 415 SUPERFAMILY SSF51735 6 190 2.27E-31 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18430 98c5374c135b221214261816987f359b 415 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 5 32 - T 23-04-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 DC74_RS18430 98c5374c135b221214261816987f359b 415 Gene3D G3DSA:3.40.50.720 6 190 2.2E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07860 636a9c41da2bf67425ad1c571b740a75 254 Gene3D G3DSA:2.60.120.10 22 86 1.3E-8 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS07860 636a9c41da2bf67425ad1c571b740a75 254 PANTHER PTHR11019:SF129 1 254 4.1E-127 T 23-04-2016 DC74_RS07860 636a9c41da2bf67425ad1c571b740a75 254 PANTHER PTHR11019 1 254 4.1E-127 T 23-04-2016 DC74_RS07860 636a9c41da2bf67425ad1c571b740a75 254 Pfam PF12833 Helix-turn-helix domain 176 251 1.6E-18 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS07860 636a9c41da2bf67425ad1c571b740a75 254 SUPERFAMILY SSF46689 207 251 2.69E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07860 636a9c41da2bf67425ad1c571b740a75 254 SMART SM00342 170 251 6.1E-17 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS07860 636a9c41da2bf67425ad1c571b740a75 254 SUPERFAMILY SSF51182 21 142 1.33E-11 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS07860 636a9c41da2bf67425ad1c571b740a75 254 Gene3D G3DSA:1.10.10.60 208 250 3.1E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07860 636a9c41da2bf67425ad1c571b740a75 254 Gene3D G3DSA:1.10.10.60 169 207 2.8E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07860 636a9c41da2bf67425ad1c571b740a75 254 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 220 235 5.7E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS07860 636a9c41da2bf67425ad1c571b740a75 254 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 235 251 5.7E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS07860 636a9c41da2bf67425ad1c571b740a75 254 Pfam PF02311 AraC-like ligand binding domain 24 109 1.1E-5 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PANTHER PTHR22912 3 307 1.2E-162 T 23-04-2016 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 23-04-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 Gene3D G3DSA:3.50.50.60 130 240 1.0E-36 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 Gene3D G3DSA:3.50.50.60 5 104 1.4E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 9.1E-38 T 23-04-2016 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 9.1E-38 T 23-04-2016 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 9.1E-38 T 23-04-2016 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 9.1E-38 T 23-04-2016 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 9.1E-38 T 23-04-2016 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 306 1.5E-121 T 23-04-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 SUPERFAMILY SSF51905 5 304 7.38E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PANTHER PTHR22912:SF48 3 307 1.2E-162 T 23-04-2016 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 1.5E-80 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.5E-80 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 1.5E-80 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 1.5E-80 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 1.5E-80 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 1.5E-80 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 1.5E-80 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 1.5E-80 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.5E-80 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 Gene3D G3DSA:3.50.50.60 270 299 3.8E-6 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 Gene3D G3DSA:3.50.50.60 105 129 3.8E-6 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS20745 76d9d37c622432b1bf9b2e4936169a46 324 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 295 6.8E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 PANTHER PTHR23115 201 631 1.9E-253 T 23-04-2016 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 Gene3D G3DSA:3.30.70.240 432 509 1.5E-29 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 SUPERFAMILY SSF52540 6 222 3.04E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 Gene3D G3DSA:2.40.50.250 512 606 1.0E-37 T 23-04-2016 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 Gene3D G3DSA:3.30.70.870 321 431 7.2E-34 T 23-04-2016 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 49 64 - T 23-04-2016 IPR031157 Tr-type G domain, conserved site DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 SUPERFAMILY SSF50447 163 185 1.39E-30 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 SUPERFAMILY SSF50447 212 316 1.39E-30 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 PRINTS PR00315 GTP-binding elongation factor signature 56 64 1.5E-15 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.5E-15 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 PRINTS PR00315 GTP-binding elongation factor signature 98 109 1.5E-15 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 PRINTS PR00315 GTP-binding elongation factor signature 82 92 1.5E-15 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 PRINTS PR00315 GTP-binding elongation factor signature 134 143 1.5E-15 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 Gene3D G3DSA:2.40.30.10 223 320 3.2E-29 T 23-04-2016 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 PANTHER PTHR23115:SF14 1 181 1.9E-253 T 23-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 Pfam PF00009 Elongation factor Tu GTP binding domain 7 212 1.7E-51 T 23-04-2016 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 PANTHER PTHR23115:SF14 201 631 1.9E-253 T 23-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 PANTHER PTHR23115 1 181 1.9E-253 T 23-04-2016 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 627 1.8E-287 T 23-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 162 2.1E-21 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 Gene3D G3DSA:3.40.50.300 5 222 2.1E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 Pfam PF00679 Elongation factor G C-terminus 426 505 1.5E-19 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 Pfam PF03144 Elongation factor Tu domain 2 236 306 1.1E-10 T 23-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 SUPERFAMILY SSF54980 428 542 1.68E-26 T 23-04-2016 IPR009022 Elongation factor G, III-V domain DC74_RS25805 1b4387c055ef687f4e22684efadda0a6 636 SUPERFAMILY SSF54980 320 417 1.25E-9 T 23-04-2016 IPR009022 Elongation factor G, III-V domain DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 PRINTS PR00359 B-class P450 signature 197 219 3.8E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 PRINTS PR00359 B-class P450 signature 353 364 3.8E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 PRINTS PR00359 B-class P450 signature 295 322 3.8E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 PRINTS PR00359 B-class P450 signature 140 156 3.8E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 PRINTS PR00359 B-class P450 signature 94 105 3.8E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 PRINTS PR00359 B-class P450 signature 157 172 3.8E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 PRINTS PR00359 B-class P450 signature 278 289 3.8E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 PRINTS PR00359 B-class P450 signature 323 338 3.8E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 PRINTS PR00359 B-class P450 signature 344 353 3.8E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 Gene3D G3DSA:1.10.630.10 10 403 2.4E-102 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 Pfam PF00067 Cytochrome P450 277 371 1.8E-13 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 PANTHER PTHR24286 50 410 2.1E-70 T 23-04-2016 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 PANTHER PTHR24286:SF42 50 410 2.1E-70 T 23-04-2016 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 SUPERFAMILY SSF48264 22 403 3.67E-83 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06000 a4b64be9cadd8f70556885697ea58374 412 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 PANTHER PTHR24319:SF32 1 248 1.3E-51 T 23-04-2016 DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 SUPERFAMILY SSF51735 3 239 9.18E-64 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 7.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 7.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 7.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 7.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 7.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 PANTHER PTHR24319 1 248 1.3E-51 T 23-04-2016 DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 192 1.5E-4 T 23-04-2016 DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 Pfam PF00106 short chain dehydrogenase 10 202 6.4E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 Gene3D G3DSA:3.40.50.720 5 244 1.3E-65 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 4.3E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 4.3E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS09045 096afd23255abe0e8a3336bc677d316f 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.3E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS31890 2618d043f86e75c5dc3b4f68bf855727 134 Gene3D G3DSA:3.10.180.10 12 127 1.8E-32 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS31890 2618d043f86e75c5dc3b4f68bf855727 134 SUPERFAMILY SSF54593 18 130 1.02E-18 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS16090 53dc2d41cf88a8c235cfb0ed20c88485 472 ProSitePatterns PS00571 Amidases signature. 159 190 - T 23-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS16090 53dc2d41cf88a8c235cfb0ed20c88485 472 Pfam PF01425 Amidase 29 452 2.9E-102 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS16090 53dc2d41cf88a8c235cfb0ed20c88485 472 PANTHER PTHR11895:SF66 7 470 3.4E-134 T 23-04-2016 DC74_RS16090 53dc2d41cf88a8c235cfb0ed20c88485 472 Gene3D G3DSA:3.90.1300.10 7 468 4.7E-133 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS16090 53dc2d41cf88a8c235cfb0ed20c88485 472 PANTHER PTHR11895 7 470 3.4E-134 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS16090 53dc2d41cf88a8c235cfb0ed20c88485 472 SUPERFAMILY SSF75304 6 460 1.31E-132 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS11180 5664229a8d5839ac38901ce05a8cfb16 600 PANTHER PTHR34384:SF5 8 596 6.4E-260 T 23-04-2016 DC74_RS11180 5664229a8d5839ac38901ce05a8cfb16 600 Pfam PF04183 IucA / IucC family 148 397 2.6E-78 T 23-04-2016 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 DC74_RS11180 5664229a8d5839ac38901ce05a8cfb16 600 Pfam PF06276 Ferric iron reductase FhuF-like transporter 418 575 7.5E-40 T 23-04-2016 IPR022770 Ferric iron reductase FhuF domain DC74_RS11180 5664229a8d5839ac38901ce05a8cfb16 600 PANTHER PTHR34384 8 596 6.4E-260 T 23-04-2016 DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 PANTHER PTHR24031 1103 1204 1.1E-30 T 23-04-2016 DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 PANTHER PTHR24031 1470 1481 1.1E-30 T 23-04-2016 DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 PANTHER PTHR24031 801 839 1.1E-30 T 23-04-2016 DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 PANTHER PTHR24031 75 275 1.1E-30 T 23-04-2016 DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 PANTHER PTHR24031 757 781 1.1E-30 T 23-04-2016 DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 Gene3D G3DSA:3.40.50.300 1091 1185 2.6E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 Gene3D G3DSA:3.40.50.300 677 698 2.6E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 Pfam PF00271 Helicase conserved C-terminal domain 1098 1171 6.8E-10 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 SUPERFAMILY SSF52540 74 277 9.35E-22 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 PANTHER PTHR24031:SF249 1103 1204 1.1E-30 T 23-04-2016 DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 PANTHER PTHR24031:SF249 1470 1481 1.1E-30 T 23-04-2016 DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 PANTHER PTHR24031:SF249 801 839 1.1E-30 T 23-04-2016 DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 PANTHER PTHR24031:SF249 75 275 1.1E-30 T 23-04-2016 DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 PANTHER PTHR24031:SF249 757 781 1.1E-30 T 23-04-2016 DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 Gene3D G3DSA:3.40.50.300 73 276 7.7E-22 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 Pfam PF09369 Domain of unknown function (DUF1998) 1705 1794 1.1E-9 T 23-04-2016 IPR018973 DEAD/DEAH-box helicase, putative DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 SMART SM00490 1087 1172 3.8E-14 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 SUPERFAMILY SSF52540 97 155 5.58E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 SUPERFAMILY SSF52540 1086 1193 5.58E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 Pfam PF00270 DEAD/DEAH box helicase 79 254 2.9E-13 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS25685 d0d51de3ca1644e7c96930d4e13c2b73 2089 SMART SM00487 72 301 4.5E-12 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS12815 2e569e3fd8bd39cb7120a8d9f77cec77 341 Pfam PF00877 NlpC/P60 family 241 336 2.5E-24 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS12815 2e569e3fd8bd39cb7120a8d9f77cec77 341 Gene3D G3DSA:3.90.1720.10 224 331 4.5E-39 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS12815 2e569e3fd8bd39cb7120a8d9f77cec77 341 PANTHER PTHR21666 224 332 1.5E-32 T 23-04-2016 DC74_RS12815 2e569e3fd8bd39cb7120a8d9f77cec77 341 SUPERFAMILY SSF54001 224 332 2.01E-36 T 23-04-2016 DC74_RS31115 6cad586aca76405385054366e5aed04d 580 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 171 1.7E-41 T 23-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DC74_RS31115 6cad586aca76405385054366e5aed04d 580 Gene3D G3DSA:3.40.50.970 357 551 2.5E-55 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS31115 6cad586aca76405385054366e5aed04d 580 SUPERFAMILY SSF52518 4 177 5.4E-41 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS31115 6cad586aca76405385054366e5aed04d 580 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 320 1.1E-29 T 23-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DC74_RS31115 6cad586aca76405385054366e5aed04d 580 SUPERFAMILY SSF52518 360 542 5.05E-57 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS31115 6cad586aca76405385054366e5aed04d 580 Gene3D G3DSA:3.40.50.1220 186 341 2.0E-38 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS31115 6cad586aca76405385054366e5aed04d 580 SUPERFAMILY SSF52467 183 346 3.13E-40 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS31115 6cad586aca76405385054366e5aed04d 580 Gene3D G3DSA:3.40.50.970 3 177 7.7E-51 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS31115 6cad586aca76405385054366e5aed04d 580 PANTHER PTHR18968:SF12 1 575 0.0 T 23-04-2016 DC74_RS31115 6cad586aca76405385054366e5aed04d 580 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 529 9.2E-40 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS31115 6cad586aca76405385054366e5aed04d 580 PANTHER PTHR18968 1 575 0.0 T 23-04-2016 DC74_RS08000 e9937e280203b3e26632fcce63f2d206 204 SUPERFAMILY SSF47413 15 81 6.7E-19 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS08000 e9937e280203b3e26632fcce63f2d206 204 SUPERFAMILY SSF51182 78 180 1.65E-20 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS08000 e9937e280203b3e26632fcce63f2d206 204 Gene3D G3DSA:1.10.260.40 15 86 9.7E-23 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS08000 e9937e280203b3e26632fcce63f2d206 204 PANTHER PTHR10245 15 191 2.6E-32 T 23-04-2016 DC74_RS08000 e9937e280203b3e26632fcce63f2d206 204 Pfam PF01381 Helix-turn-helix 21 75 1.0E-16 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS08000 e9937e280203b3e26632fcce63f2d206 204 Gene3D G3DSA:2.60.120.10 101 181 2.2E-14 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS08000 e9937e280203b3e26632fcce63f2d206 204 PANTHER PTHR10245:SF20 15 191 2.6E-32 T 23-04-2016 DC74_RS08000 e9937e280203b3e26632fcce63f2d206 204 SMART SM00530 20 75 1.8E-18 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS08000 e9937e280203b3e26632fcce63f2d206 204 Pfam PF07883 Cupin domain 113 181 2.7E-15 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS10330 a6c91958409ca6b4d25391cf1d3b2781 588 SMART SM00382 265 419 1.5E-22 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS10330 a6c91958409ca6b4d25391cf1d3b2781 588 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 52 565 1.4E-252 T 23-04-2016 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 DC74_RS10330 a6c91958409ca6b4d25391cf1d3b2781 588 Pfam PF16450 Proteasomal ATPase OB/ID domain 97 226 1.5E-53 T 23-04-2016 IPR032501 Proteasomal ATPase, OB/ID domain DC74_RS10330 a6c91958409ca6b4d25391cf1d3b2781 588 PANTHER PTHR23077 220 444 5.1E-85 T 23-04-2016 DC74_RS10330 a6c91958409ca6b4d25391cf1d3b2781 588 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 269 417 6.9E-48 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS10330 a6c91958409ca6b4d25391cf1d3b2781 588 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 54 566 50.206 T 23-04-2016 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 DC74_RS10330 a6c91958409ca6b4d25391cf1d3b2781 588 SUPERFAMILY SSF52540 475 511 2.84E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10330 a6c91958409ca6b4d25391cf1d3b2781 588 SUPERFAMILY SSF52540 227 434 2.84E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10330 a6c91958409ca6b4d25391cf1d3b2781 588 ProSitePatterns PS00674 AAA-protein family signature. 387 405 - T 23-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DC74_RS10330 a6c91958409ca6b4d25391cf1d3b2781 588 Gene3D G3DSA:3.40.50.300 217 434 2.5E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12385 56df2ba363a4ce03688c145bea4031fc 201 Gene3D G3DSA:3.30.230.40 7 93 1.6E-36 T 23-04-2016 DC74_RS12385 56df2ba363a4ce03688c145bea4031fc 201 PANTHER PTHR23133:SF2 7 201 5.8E-101 T 23-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 DC74_RS12385 56df2ba363a4ce03688c145bea4031fc 201 SUPERFAMILY SSF54211 7 90 2.02E-32 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS12385 56df2ba363a4ce03688c145bea4031fc 201 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 36 180 7.6E-62 T 23-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 DC74_RS12385 56df2ba363a4ce03688c145bea4031fc 201 SUPERFAMILY SSF54211 92 185 3.41E-30 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS12385 56df2ba363a4ce03688c145bea4031fc 201 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 7 201 41.063 T 23-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 DC74_RS12385 56df2ba363a4ce03688c145bea4031fc 201 PANTHER PTHR23133 7 201 5.8E-101 T 23-04-2016 DC74_RS12385 56df2ba363a4ce03688c145bea4031fc 201 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 66 79 - T 23-04-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 DC74_RS12385 56df2ba363a4ce03688c145bea4031fc 201 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 162 174 - T 23-04-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 DC74_RS12385 56df2ba363a4ce03688c145bea4031fc 201 Gene3D G3DSA:3.30.230.40 95 201 1.4E-28 T 23-04-2016 DC74_RS29130 5969614f8c106b4b5a55b8417439ddf6 384 Gene3D G3DSA:3.40.50.1400 9 165 2.3E-39 T 23-04-2016 DC74_RS29130 5969614f8c106b4b5a55b8417439ddf6 384 Gene3D G3DSA:3.40.50.1400 166 313 3.5E-45 T 23-04-2016 DC74_RS29130 5969614f8c106b4b5a55b8417439ddf6 384 Pfam PF00762 Ferrochelatase 11 332 3.5E-91 T 23-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 DC74_RS29130 5969614f8c106b4b5a55b8417439ddf6 384 Hamap MF_00323 Ferrochelatase [hemH]. 9 333 29.599 T 23-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 DC74_RS29130 5969614f8c106b4b5a55b8417439ddf6 384 SUPERFAMILY SSF53800 9 345 6.05E-79 T 23-04-2016 DC74_RS29130 5969614f8c106b4b5a55b8417439ddf6 384 PANTHER PTHR11108 8 332 8.5E-80 T 23-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 Gene3D G3DSA:3.40.50.140 13 157 7.2E-49 T 23-04-2016 IPR006171 Toprim domain DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 PANTHER PTHR11390 267 597 6.7E-274 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 SMART SM00437 289 556 7.6E-119 T 23-04-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 Pfam PF01751 Toprim domain 15 136 1.3E-26 T 23-04-2016 IPR006171 Toprim domain DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 Pfam PF01131 DNA topoisomerase 151 593 1.2E-129 T 23-04-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 PANTHER PTHR11390 12 249 6.7E-274 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 PANTHER PTHR11390:SF27 12 249 6.7E-274 T 23-04-2016 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 PANTHER PTHR11390:SF27 267 597 6.7E-274 T 23-04-2016 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 SUPERFAMILY SSF56712 13 597 2.22E-179 T 23-04-2016 IPR023405 DNA topoisomerase, type IA, core domain DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 408 424 1.0E-33 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 185 203 1.0E-33 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 101 114 1.0E-33 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 519 533 1.0E-33 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 331 340 1.0E-33 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 326 340 - T 23-04-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 Pfam PF13368 Topoisomerase C-terminal repeat 644 695 1.8E-7 T 23-04-2016 IPR025589 Topoisomerase C-terminal repeat DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 Pfam PF13368 Topoisomerase C-terminal repeat 703 766 6.2E-14 T 23-04-2016 IPR025589 Topoisomerase C-terminal repeat DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 Pfam PF13368 Topoisomerase C-terminal repeat 773 823 2.4E-15 T 23-04-2016 IPR025589 Topoisomerase C-terminal repeat DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 Pfam PF13368 Topoisomerase C-terminal repeat 836 888 6.3E-20 T 23-04-2016 IPR025589 Topoisomerase C-terminal repeat DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 Gene3D G3DSA:1.10.460.10 158 205 3.1E-50 T 23-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 Gene3D G3DSA:1.10.460.10 503 597 3.1E-50 T 23-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 15 664 1.4E-240 T 23-04-2016 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 SMART SM00493 13 127 1.3E-37 T 23-04-2016 IPR006171 Toprim domain DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 Hamap MF_00952 DNA topoisomerase 1 [topA]. 13 782 55.046 T 23-04-2016 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 SMART SM00436 127 215 3.5E-45 T 23-04-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 Gene3D G3DSA:2.70.20.10 207 355 4.8E-26 T 23-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 DC74_RS22200 f42c8caf96f201b903c10bf8479ddef6 947 Gene3D G3DSA:2.70.20.10 356 502 1.9E-34 T 23-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 DC74_RS37215 dd35ea39f8fd29b1fdfcffa4d5b0d8da 213 Gene3D G3DSA:3.40.50.150 20 173 2.8E-17 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS37215 dd35ea39f8fd29b1fdfcffa4d5b0d8da 213 Pfam PF13489 Methyltransferase domain 45 184 7.4E-10 T 23-04-2016 DC74_RS37215 dd35ea39f8fd29b1fdfcffa4d5b0d8da 213 PANTHER PTHR10108 23 164 6.4E-24 T 23-04-2016 DC74_RS37215 dd35ea39f8fd29b1fdfcffa4d5b0d8da 213 PANTHER PTHR10108:SF919 23 164 6.4E-24 T 23-04-2016 DC74_RS37215 dd35ea39f8fd29b1fdfcffa4d5b0d8da 213 SUPERFAMILY SSF53335 10 167 1.71E-20 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS31880 9f32725b17a0f55481a525b16123362b 484 Pfam PF02515 CoA-transferase family III 218 425 5.9E-50 T 23-04-2016 IPR003673 CoA-transferase family III GO:0003824 DC74_RS31880 9f32725b17a0f55481a525b16123362b 484 PANTHER PTHR24023:SF593 286 415 1.1E-13 T 23-04-2016 DC74_RS31880 9f32725b17a0f55481a525b16123362b 484 PANTHER PTHR24023 286 415 1.1E-13 T 23-04-2016 DC74_RS31880 9f32725b17a0f55481a525b16123362b 484 Gene3D G3DSA:3.40.50.10540 5 151 6.5E-6 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS31880 9f32725b17a0f55481a525b16123362b 484 Gene3D G3DSA:3.40.50.10540 216 414 7.0E-68 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS31880 9f32725b17a0f55481a525b16123362b 484 SUPERFAMILY SSF89796 6 209 2.49E-20 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS31880 9f32725b17a0f55481a525b16123362b 484 SUPERFAMILY SSF89796 216 438 3.14E-58 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS22755 68a6f07082555418e70335a7939d119f 270 Gene3D G3DSA:3.40.50.150 20 171 2.5E-26 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS22755 68a6f07082555418e70335a7939d119f 270 SUPERFAMILY SSF53335 22 182 6.53E-30 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS22755 68a6f07082555418e70335a7939d119f 270 Pfam PF08241 Methyltransferase domain 61 151 4.4E-16 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS22755 68a6f07082555418e70335a7939d119f 270 PANTHER PTHR10108 25 186 2.4E-24 T 23-04-2016 DC74_RS29680 21b954454dc161cda9344b62ac77bc1f 119 PANTHER PTHR38445:SF2 1 113 3.0E-18 T 23-04-2016 DC74_RS29680 21b954454dc161cda9344b62ac77bc1f 119 SUPERFAMILY SSF46785 6 80 4.54E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29680 21b954454dc161cda9344b62ac77bc1f 119 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 2.5E-15 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS29680 21b954454dc161cda9344b62ac77bc1f 119 SMART SM00345 17 76 1.3E-13 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS29680 21b954454dc161cda9344b62ac77bc1f 119 Gene3D G3DSA:1.10.10.10 4 77 6.1E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29680 21b954454dc161cda9344b62ac77bc1f 119 PANTHER PTHR38445 1 113 3.0E-18 T 23-04-2016 DC74_RS27735 e9024dfdfec0639a7e5ed78d2c975475 510 Pfam PF00149 Calcineurin-like phosphoesterase 187 386 9.2E-12 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS27735 e9024dfdfec0639a7e5ed78d2c975475 510 Gene3D G3DSA:3.60.21.10 175 508 8.8E-67 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS27735 e9024dfdfec0639a7e5ed78d2c975475 510 PANTHER PTHR22953 68 430 9.5E-55 T 23-04-2016 DC74_RS27735 e9024dfdfec0639a7e5ed78d2c975475 510 PANTHER PTHR22953 451 507 9.5E-55 T 23-04-2016 DC74_RS27735 e9024dfdfec0639a7e5ed78d2c975475 510 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 64 169 6.0E-15 T 23-04-2016 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 DC74_RS27735 e9024dfdfec0639a7e5ed78d2c975475 510 Gene3D G3DSA:2.60.40.380 64 172 5.5E-10 T 23-04-2016 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 DC74_RS27735 e9024dfdfec0639a7e5ed78d2c975475 510 SUPERFAMILY SSF49363 50 171 5.89E-14 T 23-04-2016 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 DC74_RS27735 e9024dfdfec0639a7e5ed78d2c975475 510 SUPERFAMILY SSF56300 176 504 4.91E-45 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS27735 e9024dfdfec0639a7e5ed78d2c975475 510 PANTHER PTHR22953:SF0 68 430 9.5E-55 T 23-04-2016 DC74_RS27735 e9024dfdfec0639a7e5ed78d2c975475 510 PANTHER PTHR22953:SF0 451 507 9.5E-55 T 23-04-2016 DC74_RS10860 e5847b66fe27b564fe2e112ace985a06 314 SMART SM00244 22 180 5.6E-61 T 23-04-2016 IPR001107 Band 7 domain DC74_RS10860 e5847b66fe27b564fe2e112ace985a06 314 PRINTS PR00721 Stomatin signature 175 196 3.2E-59 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS10860 e5847b66fe27b564fe2e112ace985a06 314 PRINTS PR00721 Stomatin signature 29 51 3.2E-59 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS10860 e5847b66fe27b564fe2e112ace985a06 314 PRINTS PR00721 Stomatin signature 132 155 3.2E-59 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS10860 e5847b66fe27b564fe2e112ace985a06 314 PRINTS PR00721 Stomatin signature 200 223 3.2E-59 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS10860 e5847b66fe27b564fe2e112ace985a06 314 PRINTS PR00721 Stomatin signature 77 98 3.2E-59 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS10860 e5847b66fe27b564fe2e112ace985a06 314 PRINTS PR00721 Stomatin signature 112 129 3.2E-59 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS10860 e5847b66fe27b564fe2e112ace985a06 314 PRINTS PR00721 Stomatin signature 156 174 3.2E-59 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS10860 e5847b66fe27b564fe2e112ace985a06 314 Pfam PF01145 SPFH domain / Band 7 family 26 196 1.3E-32 T 23-04-2016 IPR001107 Band 7 domain DC74_RS10860 e5847b66fe27b564fe2e112ace985a06 314 PANTHER PTHR10264 18 251 2.4E-95 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS10860 e5847b66fe27b564fe2e112ace985a06 314 SUPERFAMILY SSF117892 54 187 1.44E-39 T 23-04-2016 IPR001107 Band 7 domain DC74_RS10860 e5847b66fe27b564fe2e112ace985a06 314 PANTHER PTHR10264:SF60 18 251 2.4E-95 T 23-04-2016 DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 Gene3D G3DSA:3.30.1490.20 137 192 1.3E-18 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 588 605 - T 23-04-2016 IPR001882 Biotin-binding site DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 Pfam PF02785 Biotin carboxylase C-terminal domain 324 427 1.2E-29 T 23-04-2016 IPR005482 Biotin carboxylase, C-terminal DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 3.8E-41 T 23-04-2016 IPR005481 Biotin carboxylase-like, N-terminal domain DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 Gene3D G3DSA:3.30.470.20 194 436 1.5E-87 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 SUPERFAMILY SSF51230 554 631 6.02E-19 T 23-04-2016 IPR011053 Single hybrid motif DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 Pfam PF00364 Biotin-requiring enzyme 566 630 1.1E-15 T 23-04-2016 IPR000089 Biotin/lipoyl attachment DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 SUPERFAMILY SSF56059 82 318 1.2E-58 T 23-04-2016 DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 SUPERFAMILY SSF51246 318 435 5.76E-33 T 23-04-2016 IPR011054 Rudiment single hybrid motif DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 276 283 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 136 312 7.8E-61 T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 SMART SM00878 324 429 2.2E-46 T 23-04-2016 IPR005482 Biotin carboxylase, C-terminal DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 SUPERFAMILY SSF52440 1 112 1.01E-43 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 Gene3D G3DSA:3.40.50.20 1 128 2.2E-47 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 PANTHER PTHR18866:SF85 1 631 0.0 T 23-04-2016 DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 PANTHER PTHR18866 1 631 0.0 T 23-04-2016 DC74_RS23870 842cd2d8c766f32dc99482328a6083d5 633 Gene3D G3DSA:2.40.50.100 560 631 2.5E-22 T 23-04-2016 DC74_RS15895 b6219faa11dec2008697710fd4fde6b6 402 PANTHER PTHR10909:SF190 3 400 2.0E-219 T 23-04-2016 DC74_RS15895 b6219faa11dec2008697710fd4fde6b6 402 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 240 7.7E-21 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS15895 b6219faa11dec2008697710fd4fde6b6 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 119 1.0E-30 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS15895 b6219faa11dec2008697710fd4fde6b6 402 Gene3D G3DSA:1.20.140.10 241 400 3.3E-55 T 23-04-2016 DC74_RS15895 b6219faa11dec2008697710fd4fde6b6 402 PANTHER PTHR10909 3 400 2.0E-219 T 23-04-2016 DC74_RS15895 b6219faa11dec2008697710fd4fde6b6 402 SUPERFAMILY SSF47203 250 400 9.18E-47 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS15895 b6219faa11dec2008697710fd4fde6b6 402 Gene3D G3DSA:2.40.110.10 122 240 9.4E-35 T 23-04-2016 DC74_RS15895 b6219faa11dec2008697710fd4fde6b6 402 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 359 378 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS15895 b6219faa11dec2008697710fd4fde6b6 402 SUPERFAMILY SSF56645 4 264 1.44E-73 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS15895 b6219faa11dec2008697710fd4fde6b6 402 Gene3D G3DSA:1.10.540.10 6 120 5.0E-33 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS15895 b6219faa11dec2008697710fd4fde6b6 402 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 252 400 6.3E-43 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS09925 4a0dbbe0384ce8f816714e740018ed5b 251 Gene3D G3DSA:1.10.10.10 87 166 1.3E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09925 4a0dbbe0384ce8f816714e740018ed5b 251 Pfam PF13936 Helix-turn-helix domain 5 45 5.4E-14 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain DC74_RS09925 4a0dbbe0384ce8f816714e740018ed5b 251 PANTHER PTHR10948 1 171 5.0E-30 T 23-04-2016 DC74_RS09925 4a0dbbe0384ce8f816714e740018ed5b 251 SUPERFAMILY SSF46785 86 170 4.94E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09925 4a0dbbe0384ce8f816714e740018ed5b 251 Pfam PF12802 MarR family 104 162 1.6E-12 T 23-04-2016 DC74_RS09925 4a0dbbe0384ce8f816714e740018ed5b 251 Gene3D G3DSA:1.10.10.10 5 43 9.3E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09925 4a0dbbe0384ce8f816714e740018ed5b 251 SMART SM00347 98 205 0.0027 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS13770 74390f524efdf24380257427781d452b 62 Pfam PF04149 Domain of unknown function (DUF397) 7 59 4.1E-21 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS32980 29af6365a051f457b1cb5dff557bb176 99 SUPERFAMILY SSF54909 1 83 9.12E-19 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS32980 29af6365a051f457b1cb5dff557bb176 99 Gene3D G3DSA:3.30.70.1060 11 82 2.0E-10 T 23-04-2016 DC74_RS32980 29af6365a051f457b1cb5dff557bb176 99 PANTHER PTHR37828:SF1 1 97 1.6E-27 T 23-04-2016 DC74_RS32980 29af6365a051f457b1cb5dff557bb176 99 Pfam PF03795 YCII-related domain 1 82 5.3E-17 T 23-04-2016 IPR005545 YCII-related DC74_RS32980 29af6365a051f457b1cb5dff557bb176 99 PANTHER PTHR37828 1 97 1.6E-27 T 23-04-2016 DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 SUPERFAMILY SSF55060 173 288 1.2E-27 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 Gene3D G3DSA:3.30.230.10 10 161 2.6E-58 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 TIGRFAM TIGR00191 thrB: homoserine kinase 11 280 2.0E-64 T 23-04-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 Pfam PF00288 GHMP kinases N terminal domain 88 151 2.6E-12 T 23-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 Hamap MF_00384 Homoserine kinase [thrB]. 11 300 29.443 T 23-04-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 Gene3D G3DSA:3.30.70.890 171 293 1.7E-35 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 PRINTS PR00958 Homoserine kinase signature 254 269 1.8E-33 T 23-04-2016 DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 PRINTS PR00958 Homoserine kinase signature 101 116 1.8E-33 T 23-04-2016 DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 PRINTS PR00958 Homoserine kinase signature 138 151 1.8E-33 T 23-04-2016 DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 PRINTS PR00958 Homoserine kinase signature 18 33 1.8E-33 T 23-04-2016 DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 PRINTS PR00958 Homoserine kinase signature 177 194 1.8E-33 T 23-04-2016 DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 Pfam PF08544 GHMP kinases C terminal 222 279 3.4E-6 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 SUPERFAMILY SSF54211 11 158 7.51E-31 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 PANTHER PTHR20861:SF1 11 295 1.1E-79 T 23-04-2016 DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 PANTHER PTHR20861 11 295 1.1E-79 T 23-04-2016 DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 PIRSF PIRSF000676 7 298 1.0E-84 T 23-04-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 DC74_RS26860 d5f228f85acfaa75dde6097e32c5b62f 305 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 94 105 - T 23-04-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 DC74_RS35845 3670813d5fbcbb5880a898b091978b36 593 SUPERFAMILY SSF56762 12 571 2.88E-113 T 23-04-2016 IPR029014 NiFe hydrogenase-like DC74_RS35845 3670813d5fbcbb5880a898b091978b36 593 PANTHER PTHR11993 554 578 3.6E-54 T 23-04-2016 DC74_RS35845 3670813d5fbcbb5880a898b091978b36 593 PANTHER PTHR11993 353 534 3.6E-54 T 23-04-2016 DC74_RS35845 3670813d5fbcbb5880a898b091978b36 593 PANTHER PTHR11993 20 130 3.6E-54 T 23-04-2016 DC74_RS35845 3670813d5fbcbb5880a898b091978b36 593 PANTHER PTHR11993 172 240 3.6E-54 T 23-04-2016 DC74_RS35845 3670813d5fbcbb5880a898b091978b36 593 Gene3D G3DSA:1.10.645.10 16 571 3.8E-155 T 23-04-2016 IPR029014 NiFe hydrogenase-like DC74_RS35845 3670813d5fbcbb5880a898b091978b36 593 Pfam PF00374 Nickel-dependent hydrogenase 53 134 2.3E-17 T 23-04-2016 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DC74_RS35845 3670813d5fbcbb5880a898b091978b36 593 Pfam PF00374 Nickel-dependent hydrogenase 175 571 1.3E-44 T 23-04-2016 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DC74_RS35845 3670813d5fbcbb5880a898b091978b36 593 PANTHER PTHR11993:SF22 554 578 3.6E-54 T 23-04-2016 DC74_RS35845 3670813d5fbcbb5880a898b091978b36 593 PANTHER PTHR11993:SF22 353 534 3.6E-54 T 23-04-2016 DC74_RS35845 3670813d5fbcbb5880a898b091978b36 593 PANTHER PTHR11993:SF22 20 130 3.6E-54 T 23-04-2016 DC74_RS35845 3670813d5fbcbb5880a898b091978b36 593 PANTHER PTHR11993:SF22 172 240 3.6E-54 T 23-04-2016 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 438 5.1E-140 T 23-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 PIRSF PIRSF000099 4 442 2.3E-158 T 23-04-2016 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 239 271 - T 23-04-2016 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 PRINTS PR00083 Histidinol dehydrogenase signature 373 391 6.3E-69 T 23-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 6.3E-69 T 23-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 PRINTS PR00083 Histidinol dehydrogenase signature 239 260 6.3E-69 T 23-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 PRINTS PR00083 Histidinol dehydrogenase signature 210 235 6.3E-69 T 23-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 6.3E-69 T 23-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 PRINTS PR00083 Histidinol dehydrogenase signature 261 280 6.3E-69 T 23-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 PRINTS PR00083 Histidinol dehydrogenase signature 332 357 6.3E-69 T 23-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 PANTHER PTHR21256 16 445 1.7E-181 T 23-04-2016 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 8 439 38.707 T 23-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 SUPERFAMILY SSF53720 26 443 5.3E-71 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 Gene3D G3DSA:3.40.50.1980 30 249 1.6E-78 T 23-04-2016 DC74_RS12395 f0ef91d6b4fb61ddfbc86381d4b520ad 447 Pfam PF00815 Histidinol dehydrogenase 23 439 2.5E-155 T 23-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 DC74_RS13785 242182f24ed238688899e865a8840124 693 SUPERFAMILY SSF46785 556 657 1.36E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13785 242182f24ed238688899e865a8840124 693 Gene3D G3DSA:1.10.10.10 547 658 2.1E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13785 242182f24ed238688899e865a8840124 693 Pfam PF07690 Major Facilitator Superfamily 27 419 4.6E-53 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS13785 242182f24ed238688899e865a8840124 693 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 499 6.4E-82 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS13785 242182f24ed238688899e865a8840124 693 Gene3D G3DSA:1.20.1250.20 24 201 1.1E-35 T 23-04-2016 DC74_RS13785 242182f24ed238688899e865a8840124 693 Gene3D G3DSA:1.20.1250.20 274 435 9.8E-21 T 23-04-2016 DC74_RS13785 242182f24ed238688899e865a8840124 693 Gene3D G3DSA:1.20.1250.20 482 505 9.8E-21 T 23-04-2016 DC74_RS13785 242182f24ed238688899e865a8840124 693 PANTHER PTHR23501:SF73 13 539 1.2E-215 T 23-04-2016 DC74_RS13785 242182f24ed238688899e865a8840124 693 SUPERFAMILY SSF103473 14 204 2.09E-71 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS13785 242182f24ed238688899e865a8840124 693 SUPERFAMILY SSF103473 477 504 2.09E-71 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS13785 242182f24ed238688899e865a8840124 693 SUPERFAMILY SSF103473 257 429 2.09E-71 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS13785 242182f24ed238688899e865a8840124 693 PANTHER PTHR23501 13 539 1.2E-215 T 23-04-2016 DC74_RS23385 7832618974ebd2e71224c61011c25d5a 218 Pfam PF00589 Phage integrase family 24 200 2.3E-24 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS23385 7832618974ebd2e71224c61011c25d5a 218 SUPERFAMILY SSF56349 7 207 2.8E-46 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DC74_RS23385 7832618974ebd2e71224c61011c25d5a 218 PANTHER PTHR30349 12 218 7.1E-50 T 23-04-2016 DC74_RS23385 7832618974ebd2e71224c61011c25d5a 218 PANTHER PTHR30349:SF20 12 218 7.1E-50 T 23-04-2016 DC74_RS23385 7832618974ebd2e71224c61011c25d5a 218 Gene3D G3DSA:1.10.443.10 16 207 1.2E-44 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS06400 f58ff97add25e88cb1e0674bb099f188 77 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.1E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS06400 f58ff97add25e88cb1e0674bb099f188 77 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.1E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS06400 f58ff97add25e88cb1e0674bb099f188 77 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 1.1E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS06400 f58ff97add25e88cb1e0674bb099f188 77 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 59 1.2E-12 T 23-04-2016 DC74_RS06400 f58ff97add25e88cb1e0674bb099f188 77 PANTHER PTHR36923 1 70 1.0E-14 T 23-04-2016 DC74_RS06400 f58ff97add25e88cb1e0674bb099f188 77 Gene3D G3DSA:3.30.70.20 1 61 1.5E-13 T 23-04-2016 DC74_RS06400 f58ff97add25e88cb1e0674bb099f188 77 SUPERFAMILY SSF54862 2 60 3.49E-12 T 23-04-2016 DC74_RS06400 f58ff97add25e88cb1e0674bb099f188 77 PANTHER PTHR36923:SF1 1 70 1.0E-14 T 23-04-2016 DC74_RS26095 c4b4f6545862bc31e9a10be59599edcd 343 PRINTS PR00111 Alpha/beta hydrolase fold signature 146 159 1.6E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS26095 c4b4f6545862bc31e9a10be59599edcd 343 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 145 1.6E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS26095 c4b4f6545862bc31e9a10be59599edcd 343 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 102 1.6E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS26095 c4b4f6545862bc31e9a10be59599edcd 343 Pfam PF00561 alpha/beta hydrolase fold 65 310 7.7E-26 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS26095 c4b4f6545862bc31e9a10be59599edcd 343 PANTHER PTHR10992 58 325 7.1E-58 T 23-04-2016 DC74_RS26095 c4b4f6545862bc31e9a10be59599edcd 343 Gene3D G3DSA:3.40.50.1820 43 323 1.3E-53 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS26095 c4b4f6545862bc31e9a10be59599edcd 343 PANTHER PTHR10992:SF107 58 325 7.1E-58 T 23-04-2016 DC74_RS26095 c4b4f6545862bc31e9a10be59599edcd 343 SUPERFAMILY SSF53474 58 321 5.63E-52 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS07325 44d6883f0b87559cd2c471cf9d9942b2 140 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 68 5.3E-19 T 23-04-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 DC74_RS07325 44d6883f0b87559cd2c471cf9d9942b2 140 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 74 138 9.5E-20 T 23-04-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 DC74_RS07325 44d6883f0b87559cd2c471cf9d9942b2 140 SUPERFAMILY SSF50331 1 69 4.13E-19 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal DC74_RS07325 44d6883f0b87559cd2c471cf9d9942b2 140 Gene3D G3DSA:2.40.50.100 74 137 5.8E-22 T 23-04-2016 DC74_RS07325 44d6883f0b87559cd2c471cf9d9942b2 140 SUPERFAMILY SSF50331 50 135 4.16E-20 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal DC74_RS07325 44d6883f0b87559cd2c471cf9d9942b2 140 Pfam PF03459 TOBE domain 4 66 3.4E-17 T 23-04-2016 IPR005116 Transport-associated OB, type 1 DC74_RS07325 44d6883f0b87559cd2c471cf9d9942b2 140 Pfam PF03459 TOBE domain 75 136 1.8E-19 T 23-04-2016 IPR005116 Transport-associated OB, type 1 DC74_RS07325 44d6883f0b87559cd2c471cf9d9942b2 140 Gene3D G3DSA:2.40.50.100 1 68 8.9E-23 T 23-04-2016 DC74_RS32585 55ed7acc560f48009e7841e0da6bec47 120 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 4 95 3.3E-26 T 23-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein DC74_RS32585 55ed7acc560f48009e7841e0da6bec47 120 PIRSF PIRSF006113 1 120 1.3E-25 T 23-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein DC74_RS32585 55ed7acc560f48009e7841e0da6bec47 120 Gene3D G3DSA:3.30.479.10 1 119 1.9E-34 T 23-04-2016 DC74_RS32585 55ed7acc560f48009e7841e0da6bec47 120 PANTHER PTHR12589 1 119 5.0E-32 T 23-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein DC74_RS32585 55ed7acc560f48009e7841e0da6bec47 120 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 119 8.7E-31 T 23-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein DC74_RS32585 55ed7acc560f48009e7841e0da6bec47 120 SUPERFAMILY SSF55620 1 119 2.99E-35 T 23-04-2016 DC74_RS35350 2a71016a6cde8a7469d509002ef9bb11 400 Gene3D G3DSA:3.50.50.60 24 106 9.0E-29 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35350 2a71016a6cde8a7469d509002ef9bb11 400 Gene3D G3DSA:3.50.50.60 164 238 9.0E-29 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35350 2a71016a6cde8a7469d509002ef9bb11 400 Gene3D G3DSA:3.50.50.60 362 395 9.0E-29 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35350 2a71016a6cde8a7469d509002ef9bb11 400 PANTHER PTHR13847 5 250 2.0E-28 T 23-04-2016 DC74_RS35350 2a71016a6cde8a7469d509002ef9bb11 400 PANTHER PTHR13847 279 397 2.0E-28 T 23-04-2016 DC74_RS35350 2a71016a6cde8a7469d509002ef9bb11 400 Pfam PF01266 FAD dependent oxidoreductase 30 397 2.4E-41 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DC74_RS35350 2a71016a6cde8a7469d509002ef9bb11 400 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 30 396 9.8E-133 T 23-04-2016 IPR017741 FAD-dependent oxidoreductase, HpnW DC74_RS35350 2a71016a6cde8a7469d509002ef9bb11 400 Gene3D G3DSA:3.30.9.10 109 163 1.3E-7 T 23-04-2016 DC74_RS35350 2a71016a6cde8a7469d509002ef9bb11 400 Gene3D G3DSA:3.30.9.10 239 316 1.3E-7 T 23-04-2016 DC74_RS35350 2a71016a6cde8a7469d509002ef9bb11 400 SUPERFAMILY SSF51905 373 394 6.34E-35 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35350 2a71016a6cde8a7469d509002ef9bb11 400 SUPERFAMILY SSF51905 30 239 6.34E-35 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 392 401 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 SUPERFAMILY SSF48264 60 438 2.36E-83 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00385 P450 superfamily signature 323 334 3.9E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00385 P450 superfamily signature 390 399 3.9E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00385 P450 superfamily signature 399 410 3.9E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00385 P450 superfamily signature 288 305 3.9E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PANTHER PTHR11712 1 445 4.9E-92 T 23-04-2016 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00359 B-class P450 signature 181 197 3.2E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00359 B-class P450 signature 340 367 3.2E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00359 B-class P450 signature 241 263 3.2E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00359 B-class P450 signature 399 410 3.2E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00359 B-class P450 signature 131 142 3.2E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00359 B-class P450 signature 368 383 3.2E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00359 B-class P450 signature 323 334 3.2E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00359 B-class P450 signature 198 213 3.2E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 PRINTS PR00359 B-class P450 signature 390 399 3.2E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 Gene3D G3DSA:1.10.630.10 60 447 2.6E-101 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02395 7d29d26b7a4910cc0b763201ea87181d 453 Pfam PF00067 Cytochrome P450 245 428 3.4E-26 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS07615 9606b7fd28278df96deb7faa7023fb41 292 SUPERFAMILY SSF53850 79 227 5.18E-14 T 23-04-2016 DC74_RS07615 9606b7fd28278df96deb7faa7023fb41 292 Pfam PF09084 NMT1/THI5 like 82 222 3.7E-6 T 23-04-2016 IPR015168 SsuA/THI5-like DC74_RS07615 9606b7fd28278df96deb7faa7023fb41 292 Gene3D G3DSA:3.40.190.10 86 167 4.7E-11 T 23-04-2016 DC74_RS23605 99f1576c8e1b792dc854150833ba1653 288 PANTHER PTHR18966:SF191 33 227 2.0E-15 T 23-04-2016 DC74_RS23605 99f1576c8e1b792dc854150833ba1653 288 Gene3D G3DSA:3.40.190.10 115 214 1.5E-15 T 23-04-2016 DC74_RS23605 99f1576c8e1b792dc854150833ba1653 288 SUPERFAMILY SSF53850 8 248 5.88E-42 T 23-04-2016 DC74_RS23605 99f1576c8e1b792dc854150833ba1653 288 Gene3D G3DSA:3.40.190.10 218 248 7.9E-19 T 23-04-2016 DC74_RS23605 99f1576c8e1b792dc854150833ba1653 288 Gene3D G3DSA:3.40.190.10 35 114 7.9E-19 T 23-04-2016 DC74_RS23605 99f1576c8e1b792dc854150833ba1653 288 SMART SM00062 37 273 1.1E-27 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS23605 99f1576c8e1b792dc854150833ba1653 288 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 246 2.6E-33 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS23605 99f1576c8e1b792dc854150833ba1653 288 PANTHER PTHR18966 33 227 2.0E-15 T 23-04-2016 DC74_RS18475 d63b8db4d2d3d3ba453c9a816160666f 336 SUPERFAMILY SSF51735 110 297 2.96E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18475 d63b8db4d2d3d3ba453c9a816160666f 336 PANTHER PTHR10996:SF167 2 333 7.2E-111 T 23-04-2016 DC74_RS18475 d63b8db4d2d3d3ba453c9a816160666f 336 Gene3D G3DSA:3.40.50.720 123 298 5.6E-54 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18475 d63b8db4d2d3d3ba453c9a816160666f 336 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 35 327 4.4E-11 T 23-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 DC74_RS18475 d63b8db4d2d3d3ba453c9a816160666f 336 SUPERFAMILY SSF52283 27 136 1.04E-12 T 23-04-2016 DC74_RS18475 d63b8db4d2d3d3ba453c9a816160666f 336 PANTHER PTHR10996 2 333 7.2E-111 T 23-04-2016 DC74_RS18475 d63b8db4d2d3d3ba453c9a816160666f 336 Gene3D G3DSA:3.40.50.720 24 122 3.1E-14 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18475 d63b8db4d2d3d3ba453c9a816160666f 336 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 207 229 - T 23-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site DC74_RS18475 d63b8db4d2d3d3ba453c9a816160666f 336 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 122 296 1.2E-48 T 23-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DC74_RS02345 7ad8b22ab06d7b0adc837d7af4fe85e6 156 PANTHER PTHR33164 9 150 6.3E-34 T 23-04-2016 DC74_RS02345 7ad8b22ab06d7b0adc837d7af4fe85e6 156 SUPERFAMILY SSF46785 4 143 3.77E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02345 7ad8b22ab06d7b0adc837d7af4fe85e6 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 1.6E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS02345 7ad8b22ab06d7b0adc837d7af4fe85e6 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 1.6E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS02345 7ad8b22ab06d7b0adc837d7af4fe85e6 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 1.6E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS02345 7ad8b22ab06d7b0adc837d7af4fe85e6 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 1.6E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS02345 7ad8b22ab06d7b0adc837d7af4fe85e6 156 Gene3D G3DSA:1.10.10.10 5 140 4.8E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02345 7ad8b22ab06d7b0adc837d7af4fe85e6 156 PANTHER PTHR33164:SF16 9 150 6.3E-34 T 23-04-2016 DC74_RS02345 7ad8b22ab06d7b0adc837d7af4fe85e6 156 Pfam PF13463 Winged helix DNA-binding domain 33 99 1.3E-12 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS02345 7ad8b22ab06d7b0adc837d7af4fe85e6 156 SMART SM00347 26 126 1.6E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS05995 661af630de1086e00cce9558ead5ac8c 594 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 258 1.0E-54 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS05995 661af630de1086e00cce9558ead5ac8c 594 SUPERFAMILY SSF53901 409 430 7.54E-61 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS05995 661af630de1086e00cce9558ead5ac8c 594 SUPERFAMILY SSF53901 10 126 7.54E-61 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS05995 661af630de1086e00cce9558ead5ac8c 594 SUPERFAMILY SSF53901 153 374 7.54E-61 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS05995 661af630de1086e00cce9558ead5ac8c 594 Gene3D G3DSA:3.40.47.10 14 270 5.4E-60 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS05995 661af630de1086e00cce9558ead5ac8c 594 SMART SM00825 Beta-ketoacyl synthase 14 434 4.1E-72 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS05995 661af630de1086e00cce9558ead5ac8c 594 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 266 381 4.7E-22 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS05995 661af630de1086e00cce9558ead5ac8c 594 PANTHER PTHR11712 13 512 1.1E-116 T 23-04-2016 DC74_RS05995 661af630de1086e00cce9558ead5ac8c 594 Gene3D G3DSA:3.40.47.10 271 435 1.8E-33 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS05995 661af630de1086e00cce9558ead5ac8c 594 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 385 489 9.8E-12 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS05995 661af630de1086e00cce9558ead5ac8c 594 PANTHER PTHR11712:SF288 13 512 1.1E-116 T 23-04-2016 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 PANTHER PTHR11712 31 424 8.6E-100 T 23-04-2016 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 PRINTS PR00359 B-class P450 signature 110 121 4.2E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 PRINTS PR00359 B-class P450 signature 340 355 4.2E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 PRINTS PR00359 B-class P450 signature 361 370 4.2E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 PRINTS PR00359 B-class P450 signature 370 381 4.2E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 PRINTS PR00359 B-class P450 signature 312 339 4.2E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 PRINTS PR00359 B-class P450 signature 214 236 4.2E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 PRINTS PR00359 B-class P450 signature 294 305 4.2E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 PRINTS PR00359 B-class P450 signature 156 172 4.2E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 Pfam PF00067 Cytochrome P450 219 390 1.2E-24 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 Gene3D G3DSA:1.10.630.10 14 424 1.7E-120 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 SUPERFAMILY SSF48264 15 424 4.45E-94 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS05050 97f47664d6c7fd4fbd5da8c2acc0f7da 425 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 363 372 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS04685 e87d12d4326b896d70bb3facb3fadfc1 468 PANTHER PTHR10617 23 456 8.4E-54 T 23-04-2016 DC74_RS04685 e87d12d4326b896d70bb3facb3fadfc1 468 PANTHER PTHR10617:SF114 23 456 8.4E-54 T 23-04-2016 DC74_RS04685 e87d12d4326b896d70bb3facb3fadfc1 468 Pfam PF01494 FAD binding domain 24 364 2.2E-7 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS04685 e87d12d4326b896d70bb3facb3fadfc1 468 SUPERFAMILY SSF51905 25 206 8.75E-22 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04685 e87d12d4326b896d70bb3facb3fadfc1 468 SUPERFAMILY SSF51905 330 376 8.75E-22 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04685 e87d12d4326b896d70bb3facb3fadfc1 468 Gene3D G3DSA:3.50.50.60 312 368 3.7E-15 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04685 e87d12d4326b896d70bb3facb3fadfc1 468 Gene3D G3DSA:3.50.50.60 25 214 3.7E-15 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS25920 f06d9fb06af53e3945b0e5ed45fbd8c6 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS25920 f06d9fb06af53e3945b0e5ed45fbd8c6 108 Gene3D G3DSA:3.30.70.20 3 76 1.5E-19 T 23-04-2016 DC74_RS25920 f06d9fb06af53e3945b0e5ed45fbd8c6 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 4.0E-18 T 23-04-2016 IPR000813 7Fe ferredoxin GO:0009055 DC74_RS25920 f06d9fb06af53e3945b0e5ed45fbd8c6 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 4.0E-18 T 23-04-2016 IPR000813 7Fe ferredoxin GO:0009055 DC74_RS25920 f06d9fb06af53e3945b0e5ed45fbd8c6 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 4.0E-18 T 23-04-2016 IPR000813 7Fe ferredoxin GO:0009055 DC74_RS25920 f06d9fb06af53e3945b0e5ed45fbd8c6 108 Pfam PF00037 4Fe-4S binding domain 34 55 1.3E-8 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS25920 f06d9fb06af53e3945b0e5ed45fbd8c6 108 SUPERFAMILY SSF54862 3 91 2.54E-22 T 23-04-2016 DC74_RS25920 f06d9fb06af53e3945b0e5ed45fbd8c6 108 PANTHER PTHR11938 1 89 7.4E-34 T 23-04-2016 DC74_RS32020 7c0a10b10e169364a7cb1258f426fadd 277 PRINTS PR00069 Aldo-keto reductase signature 37 61 2.3E-49 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS32020 7c0a10b10e169364a7cb1258f426fadd 277 PRINTS PR00069 Aldo-keto reductase signature 125 142 2.3E-49 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS32020 7c0a10b10e169364a7cb1258f426fadd 277 PRINTS PR00069 Aldo-keto reductase signature 159 188 2.3E-49 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS32020 7c0a10b10e169364a7cb1258f426fadd 277 PRINTS PR00069 Aldo-keto reductase signature 197 221 2.3E-49 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS32020 7c0a10b10e169364a7cb1258f426fadd 277 PRINTS PR00069 Aldo-keto reductase signature 93 111 2.3E-49 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS32020 7c0a10b10e169364a7cb1258f426fadd 277 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 23-04-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 DC74_RS32020 7c0a10b10e169364a7cb1258f426fadd 277 Pfam PF00248 Aldo/keto reductase family 18 261 4.1E-49 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS32020 7c0a10b10e169364a7cb1258f426fadd 277 Gene3D G3DSA:3.20.20.100 6 272 1.1E-105 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS32020 7c0a10b10e169364a7cb1258f426fadd 277 PANTHER PTHR11732 3 275 3.7E-142 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS32020 7c0a10b10e169364a7cb1258f426fadd 277 SUPERFAMILY SSF51430 7 268 6.68E-96 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS32020 7c0a10b10e169364a7cb1258f426fadd 277 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 23-04-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 Gene3D G3DSA:3.40.50.720 10 243 3.3E-57 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 220 0.0012 T 23-04-2016 DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 Pfam PF00106 short chain dehydrogenase 11 197 3.4E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PANTHER PTHR24322:SF468 13 142 6.4E-41 T 23-04-2016 DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PANTHER PTHR24322:SF468 158 189 6.4E-41 T 23-04-2016 DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 7.4E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.4E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.4E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 7.4E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.4E-23 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PANTHER PTHR24322 13 142 6.4E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PANTHER PTHR24322 158 189 6.4E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PIRSF PIRSF000126 3 260 7.1E-71 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.4E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.4E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.4E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 SUPERFAMILY SSF51735 9 259 1.59E-59 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06445 0d1250c2cff7c0eeb3c99ae5e8b73df9 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS26410 2b39b2b24c1e31a4c4e39bdfd65aaf00 167 Pfam PF00583 Acetyltransferase (GNAT) family 62 143 1.2E-11 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS26410 2b39b2b24c1e31a4c4e39bdfd65aaf00 167 Gene3D G3DSA:3.40.630.30 1 153 1.8E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS26410 2b39b2b24c1e31a4c4e39bdfd65aaf00 167 PANTHER PTHR23091 1 166 1.9E-15 T 23-04-2016 DC74_RS26410 2b39b2b24c1e31a4c4e39bdfd65aaf00 167 SUPERFAMILY SSF55729 1 156 1.08E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS23280 c85acb6e99454b414ff3374d752a1ded 413 Pfam PF07690 Major Facilitator Superfamily 35 353 2.1E-32 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS23280 c85acb6e99454b414ff3374d752a1ded 413 PANTHER PTHR23517 11 412 3.0E-131 T 23-04-2016 DC74_RS23280 c85acb6e99454b414ff3374d752a1ded 413 PANTHER PTHR23517:SF3 11 412 3.0E-131 T 23-04-2016 DC74_RS23280 c85acb6e99454b414ff3374d752a1ded 413 Gene3D G3DSA:1.20.1250.20 234 411 1.8E-15 T 23-04-2016 DC74_RS23280 c85acb6e99454b414ff3374d752a1ded 413 Gene3D G3DSA:1.20.1250.20 29 210 5.1E-30 T 23-04-2016 DC74_RS23280 c85acb6e99454b414ff3374d752a1ded 413 SUPERFAMILY SSF103473 28 411 3.79E-57 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS28285 a5389b23d2fe15904664f8a8c7f2be22 484 Pfam PF00171 Aldehyde dehydrogenase family 19 478 2.4E-160 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS28285 a5389b23d2fe15904664f8a8c7f2be22 484 SUPERFAMILY SSF53720 5 480 4.19E-157 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS28285 a5389b23d2fe15904664f8a8c7f2be22 484 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS28285 a5389b23d2fe15904664f8a8c7f2be22 484 PANTHER PTHR11699 1 479 0.0 T 23-04-2016 DC74_RS28285 a5389b23d2fe15904664f8a8c7f2be22 484 PANTHER PTHR11699:SF109 1 479 0.0 T 23-04-2016 IPR015657 Aminobutyraldehyde dehydrogenase KEGG: 00330+1.2.1.19|KEGG: 00410+1.2.1.19|MetaCyc: PWY-2|MetaCyc: PWY-3|UniPathway: UPA00188 DC74_RS28285 a5389b23d2fe15904664f8a8c7f2be22 484 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS28285 a5389b23d2fe15904664f8a8c7f2be22 484 Gene3D G3DSA:3.40.309.10 269 453 3.1E-62 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS28285 a5389b23d2fe15904664f8a8c7f2be22 484 Gene3D G3DSA:3.40.605.10 8 268 1.3E-89 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS08170 3bd9ae624225e17a4fb8dc8ead9de75d 674 Gene3D G3DSA:2.30.38.10 465 539 7.1E-4 T 23-04-2016 DC74_RS08170 3bd9ae624225e17a4fb8dc8ead9de75d 674 PANTHER PTHR24095 8 672 2.9E-300 T 23-04-2016 DC74_RS08170 3bd9ae624225e17a4fb8dc8ead9de75d 674 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 54 110 3.5E-13 T 23-04-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 DC74_RS08170 3bd9ae624225e17a4fb8dc8ead9de75d 674 SUPERFAMILY SSF56801 48 645 2.22E-123 T 23-04-2016 DC74_RS08170 3bd9ae624225e17a4fb8dc8ead9de75d 674 Gene3D G3DSA:3.30.300.30 543 633 3.1E-11 T 23-04-2016 DC74_RS08170 3bd9ae624225e17a4fb8dc8ead9de75d 674 Gene3D G3DSA:3.40.50.980 119 289 4.4E-28 T 23-04-2016 DC74_RS08170 3bd9ae624225e17a4fb8dc8ead9de75d 674 PANTHER PTHR24095:SF46 8 672 2.9E-300 T 23-04-2016 DC74_RS08170 3bd9ae624225e17a4fb8dc8ead9de75d 674 Pfam PF00501 AMP-binding enzyme 120 544 1.2E-47 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS08170 3bd9ae624225e17a4fb8dc8ead9de75d 674 Gene3D G3DSA:3.40.50.980 290 424 3.4E-15 T 23-04-2016 DC74_RS08170 3bd9ae624225e17a4fb8dc8ead9de75d 674 ProSitePatterns PS00455 Putative AMP-binding domain signature. 284 295 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS08170 3bd9ae624225e17a4fb8dc8ead9de75d 674 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 13 670 0.0 T 23-04-2016 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 PANTHER PTHR22912:SF180 1 412 7.5E-73 T 23-04-2016 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 1.7E-9 T 23-04-2016 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 1.7E-9 T 23-04-2016 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 1.7E-9 T 23-04-2016 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.7E-9 T 23-04-2016 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 SUPERFAMILY SSF55424 335 425 1.0E-20 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 SUPERFAMILY SSF51905 15 192 8.87E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 320 1.5E-39 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 SUPERFAMILY SSF51905 154 331 2.39E-23 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 5.0E-10 T 23-04-2016 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 5.0E-10 T 23-04-2016 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 244 258 5.0E-10 T 23-04-2016 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 5.0E-10 T 23-04-2016 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 Gene3D G3DSA:3.50.50.60 155 332 2.0E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 Gene3D G3DSA:3.50.50.60 15 140 8.1E-24 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 PANTHER PTHR22912 1 412 7.5E-73 T 23-04-2016 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 Gene3D G3DSA:3.30.390.30 344 414 7.8E-19 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS37500 4931b4f6369b2d5629d59283ce339c07 463 Pfam PF14759 Reductase C-terminal 344 414 1.1E-9 T 23-04-2016 IPR028202 Reductase, C-terminal DC74_RS33555 beec899cdc5b4e409b5f4a3e46b736a6 191 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 177 4.0E-25 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS33555 beec899cdc5b4e409b5f4a3e46b736a6 191 SUPERFAMILY SSF109854 4 138 8.24E-21 T 23-04-2016 DC74_RS33555 beec899cdc5b4e409b5f4a3e46b736a6 191 Gene3D G3DSA:1.20.120.450 4 60 8.7E-5 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS33555 beec899cdc5b4e409b5f4a3e46b736a6 191 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 17 132 1.4E-13 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS33555 beec899cdc5b4e409b5f4a3e46b736a6 191 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 10 189 5.5E-51 T 23-04-2016 IPR017520 Conserved hypothetical protein CHP03086 DC74_RS37375 fbacae3a2ade6e3b2d434db966888635 555 PANTHER PTHR21000:SF5 9 550 1.4E-247 T 23-04-2016 DC74_RS37375 fbacae3a2ade6e3b2d434db966888635 555 SUPERFAMILY SSF143975 5 372 9.94E-118 T 23-04-2016 DC74_RS37375 fbacae3a2ade6e3b2d434db966888635 555 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 459 470 - T 23-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS37375 fbacae3a2ade6e3b2d434db966888635 555 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 23-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS37375 fbacae3a2ade6e3b2d434db966888635 555 Pfam PF00920 Dehydratase family 31 548 4.8E-189 T 23-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS37375 fbacae3a2ade6e3b2d434db966888635 555 SUPERFAMILY SSF52016 373 551 1.49E-53 T 23-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel DC74_RS37375 fbacae3a2ade6e3b2d434db966888635 555 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 550 1.9E-190 T 23-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS37375 fbacae3a2ade6e3b2d434db966888635 555 PANTHER PTHR21000 9 550 1.4E-247 T 23-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS37375 fbacae3a2ade6e3b2d434db966888635 555 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 551 41.762 T 23-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 PANTHER PTHR24322 11 128 1.4E-33 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 PANTHER PTHR24322 144 175 1.4E-33 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 Gene3D G3DSA:3.40.50.720 6 215 1.6E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 PANTHER PTHR24322:SF330 11 128 1.4E-33 T 23-04-2016 DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 PANTHER PTHR24322:SF330 144 175 1.4E-33 T 23-04-2016 DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.0E-19 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 2.0E-19 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.0E-19 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 2.0E-19 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 2.0E-19 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 Pfam PF00106 short chain dehydrogenase 7 184 7.1E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10620 84b76c165b59f59b773590480be71eaa 257 SUPERFAMILY SSF51735 5 247 3.92E-50 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 Gene3D G3DSA:2.40.30.10 205 298 6.4E-19 T 23-04-2016 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 PANTHER PTHR22924:SF2 68 456 3.0E-55 T 23-04-2016 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 SUPERFAMILY SSF52343 303 444 1.96E-24 T 23-04-2016 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 PRINTS PR00410 Phenol hydroxylase reductase family signature 311 330 8.1E-6 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 PRINTS PR00410 Phenol hydroxylase reductase family signature 232 244 8.1E-6 T 23-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 SUPERFAMILY SSF63380 205 300 5.91E-16 T 23-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 311 330 1.0E-5 T 23-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 250 257 1.0E-5 T 23-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 345 354 1.0E-5 T 23-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 SUPERFAMILY SSF46458 70 193 1.13E-21 T 23-04-2016 IPR009050 Globin-like DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 Pfam PF00042 Globin 87 160 8.3E-5 T 23-04-2016 IPR000971 Globin GO:0019825|GO:0020037 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 PANTHER PTHR22924 68 456 3.0E-55 T 23-04-2016 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 Gene3D G3DSA:1.10.490.10 69 196 1.4E-26 T 23-04-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 Pfam PF00175 Oxidoreductase NAD-binding domain 312 426 2.7E-9 T 23-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 Gene3D G3DSA:3.40.50.80 299 444 4.3E-25 T 23-04-2016 DC74_RS03885 75e7f3ed4f19a4b9555dfddc851f5ac4 470 Pfam PF00970 Oxidoreductase FAD-binding domain 208 298 4.2E-7 T 23-04-2016 IPR008333 Oxidoreductase, FAD-binding domain DC74_RS26815 e88b7f33caa15cc15307b638b04de00d 465 PANTHER PTHR30474 61 459 5.5E-179 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 DC74_RS26815 e88b7f33caa15cc15307b638b04de00d 465 Pfam PF01098 Cell cycle protein 86 442 3.7E-69 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 DC74_RS26815 e88b7f33caa15cc15307b638b04de00d 465 PANTHER PTHR30474:SF3 61 459 5.5E-179 T 23-04-2016 DC74_RS39570 bb31fefacf853a5ffadc6b3bc05605a2 198 SUPERFAMILY SSF48403 7 194 2.04E-42 T 23-04-2016 IPR020683 Ankyrin repeat-containing domain DC74_RS39570 bb31fefacf853a5ffadc6b3bc05605a2 198 Gene3D G3DSA:1.25.40.20 6 194 3.5E-41 T 23-04-2016 IPR020683 Ankyrin repeat-containing domain DC74_RS39570 bb31fefacf853a5ffadc6b3bc05605a2 198 SMART SM00248 136 170 1.6 T 23-04-2016 IPR002110 Ankyrin repeat GO:0005515 DC74_RS39570 bb31fefacf853a5ffadc6b3bc05605a2 198 SMART SM00248 36 65 0.035 T 23-04-2016 IPR002110 Ankyrin repeat GO:0005515 DC74_RS39570 bb31fefacf853a5ffadc6b3bc05605a2 198 SMART SM00248 69 98 1600.0 T 23-04-2016 IPR002110 Ankyrin repeat GO:0005515 DC74_RS39570 bb31fefacf853a5ffadc6b3bc05605a2 198 SMART SM00248 3 32 220.0 T 23-04-2016 IPR002110 Ankyrin repeat GO:0005515 DC74_RS39570 bb31fefacf853a5ffadc6b3bc05605a2 198 Pfam PF12796 Ankyrin repeats (3 copies) 83 171 1.1E-8 T 23-04-2016 IPR020683 Ankyrin repeat-containing domain DC74_RS39570 bb31fefacf853a5ffadc6b3bc05605a2 198 Pfam PF12796 Ankyrin repeats (3 copies) 6 67 5.5E-7 T 23-04-2016 IPR020683 Ankyrin repeat-containing domain DC74_RS39570 bb31fefacf853a5ffadc6b3bc05605a2 198 PANTHER PTHR24198 7 194 2.8E-38 T 23-04-2016 DC74_RS04165 3c7c87ffd3836cac444550fee742ed9d 116 SUPERFAMILY SSF54913 7 106 2.11E-29 T 23-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta DC74_RS04165 3c7c87ffd3836cac444550fee742ed9d 116 Pfam PF02641 Uncharacterized ACR, COG1993 10 104 6.5E-34 T 23-04-2016 IPR003793 Domain of unknown function DUF190 DC74_RS04165 3c7c87ffd3836cac444550fee742ed9d 116 Gene3D G3DSA:3.30.70.120 3 113 2.5E-39 T 23-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal DC74_RS04165 3c7c87ffd3836cac444550fee742ed9d 116 PANTHER PTHR35983 3 114 9.6E-39 T 23-04-2016 DC74_RS28785 b5190ddc948de254d423b615a568d645 222 PANTHER PTHR33602 58 213 8.0E-39 T 23-04-2016 DC74_RS28785 b5190ddc948de254d423b615a568d645 222 Hamap MF_01114 Regulatory protein RecX [recX]. 52 208 15.197 T 23-04-2016 IPR003783 Regulatory protein RecX GO:0006282 DC74_RS28785 b5190ddc948de254d423b615a568d645 222 Gene3D G3DSA:1.10.10.10 107 148 4.6E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28785 b5190ddc948de254d423b615a568d645 222 PANTHER PTHR33602:SF1 58 213 8.0E-39 T 23-04-2016 DC74_RS28785 b5190ddc948de254d423b615a568d645 222 Pfam PF02631 RecX family 83 203 2.7E-28 T 23-04-2016 IPR003783 Regulatory protein RecX GO:0006282 DC74_RS28785 b5190ddc948de254d423b615a568d645 222 Gene3D G3DSA:1.10.10.10 61 105 3.1E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 Pfam PF13307 Helicase C-terminal domain 471 629 3.5E-26 T 23-04-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 SMART SM00491 488 617 7.2E-40 T 23-04-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 PANTHER PTHR11472 21 634 1.4E-177 T 23-04-2016 DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 Gene3D G3DSA:3.40.50.300 460 613 5.1E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 PANTHER PTHR11472:SF37 21 634 1.4E-177 T 23-04-2016 DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 SMART SM00487 17 291 1.4E-4 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 Gene3D G3DSA:3.40.50.300 189 257 8.4E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 Gene3D G3DSA:3.40.50.300 394 403 8.4E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 Gene3D G3DSA:3.40.50.300 20 106 8.4E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 SUPERFAMILY SSF52540 189 260 4.86E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 SUPERFAMILY SSF52540 392 406 4.86E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 SUPERFAMILY SSF52540 445 600 4.86E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28920 f22141f6259dce9ae39b09345fa5d4f1 662 SUPERFAMILY SSF52540 37 85 4.86E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20890 e0a903d6be7c56061dff8e6e707eacb1 379 Pfam PF00266 Aminotransferase class-V 26 321 1.8E-28 T 23-04-2016 IPR000192 Aminotransferase class V domain DC74_RS20890 e0a903d6be7c56061dff8e6e707eacb1 379 Gene3D G3DSA:3.90.1150.10 245 357 8.2E-17 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS20890 e0a903d6be7c56061dff8e6e707eacb1 379 PANTHER PTHR21152:SF21 24 359 3.9E-54 T 23-04-2016 DC74_RS20890 e0a903d6be7c56061dff8e6e707eacb1 379 PANTHER PTHR21152 24 359 3.9E-54 T 23-04-2016 DC74_RS20890 e0a903d6be7c56061dff8e6e707eacb1 379 SUPERFAMILY SSF53383 23 356 6.69E-64 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS20890 e0a903d6be7c56061dff8e6e707eacb1 379 Gene3D G3DSA:3.40.640.10 24 244 2.8E-44 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS20890 e0a903d6be7c56061dff8e6e707eacb1 379 PIRSF PIRSF000524 22 378 3.3E-72 T 23-04-2016 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 DC74_RS20940 c7692da387dda757a5a3b37487608485 374 Gene3D G3DSA:3.90.1150.10 246 372 4.7E-31 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS20940 c7692da387dda757a5a3b37487608485 374 SUPERFAMILY SSF53383 35 371 3.38E-83 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS20940 c7692da387dda757a5a3b37487608485 374 PANTHER PTHR11808 1 374 4.6E-193 T 23-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 DC74_RS20940 c7692da387dda757a5a3b37487608485 374 PANTHER PTHR11808:SF44 1 374 4.6E-193 T 23-04-2016 DC74_RS20940 c7692da387dda757a5a3b37487608485 374 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 34 369 1.9E-79 T 23-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 DC74_RS20940 c7692da387dda757a5a3b37487608485 374 PIRSF PIRSF001434 6 373 1.4E-104 T 23-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 DC74_RS20940 c7692da387dda757a5a3b37487608485 374 Gene3D G3DSA:3.40.640.10 5 245 2.2E-62 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS08950 e279621a82785413aa8c6e46904a1f3c 216 Gene3D G3DSA:3.20.20.190 4 210 3.1E-58 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS08950 e279621a82785413aa8c6e46904a1f3c 216 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 5 207 8.7E-31 T 23-04-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 DC74_RS08950 e279621a82785413aa8c6e46904a1f3c 216 PANTHER PTHR23344 1 208 4.9E-55 T 23-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 DC74_RS08950 e279621a82785413aa8c6e46904a1f3c 216 SUPERFAMILY SSF51695 3 211 3.14E-57 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS26165 123975fbd715012781ba1f0eb5bd526d 146 Gene3D G3DSA:1.10.10.10 33 100 2.3E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26165 123975fbd715012781ba1f0eb5bd526d 146 PANTHER PTHR10815:SF2 30 144 1.1E-28 T 23-04-2016 DC74_RS26165 123975fbd715012781ba1f0eb5bd526d 146 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 34 102 7.3E-16 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS26165 123975fbd715012781ba1f0eb5bd526d 146 PANTHER PTHR10815 30 144 1.1E-28 T 23-04-2016 DC74_RS26165 123975fbd715012781ba1f0eb5bd526d 146 SUPERFAMILY SSF46767 33 100 1.22E-11 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS04820 52be4b03a26fec39835de9c0aed17670 225 SUPERFAMILY SSF53335 56 206 8.13E-16 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS04820 52be4b03a26fec39835de9c0aed17670 225 Pfam PF13649 Methyltransferase domain 63 150 2.6E-6 T 23-04-2016 DC74_RS04820 52be4b03a26fec39835de9c0aed17670 225 Gene3D G3DSA:3.40.50.150 63 205 5.6E-13 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS27960 c3af5e5977a0a93f682e060427a999f2 322 Gene3D G3DSA:3.30.1330.10 4 146 1.9E-45 T 23-04-2016 IPR016188 PurM-like, N-terminal domain DC74_RS27960 c3af5e5977a0a93f682e060427a999f2 322 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 8 312 29.032 T 23-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 DC74_RS27960 c3af5e5977a0a93f682e060427a999f2 322 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 9 315 8.3E-85 T 23-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 DC74_RS27960 c3af5e5977a0a93f682e060427a999f2 322 PANTHER PTHR30270 1 322 5.0E-114 T 23-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 DC74_RS27960 c3af5e5977a0a93f682e060427a999f2 322 Pfam PF00586 AIR synthase related protein, N-terminal domain 33 142 4.3E-22 T 23-04-2016 IPR016188 PurM-like, N-terminal domain DC74_RS27960 c3af5e5977a0a93f682e060427a999f2 322 PANTHER PTHR30270:SF0 1 322 5.0E-114 T 23-04-2016 DC74_RS27960 c3af5e5977a0a93f682e060427a999f2 322 PIRSF PIRSF005303 3 315 1.5E-91 T 23-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 DC74_RS27960 c3af5e5977a0a93f682e060427a999f2 322 SUPERFAMILY SSF56042 148 296 6.63E-33 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS27960 c3af5e5977a0a93f682e060427a999f2 322 Pfam PF02769 AIR synthase related protein, C-terminal domain 156 244 4.5E-6 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS27960 c3af5e5977a0a93f682e060427a999f2 322 SUPERFAMILY SSF55326 5 142 1.94E-34 T 23-04-2016 DC74_RS27960 c3af5e5977a0a93f682e060427a999f2 322 Gene3D G3DSA:3.90.650.10 151 315 6.5E-51 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS02990 67c82e7786b0f84cf0273e1f3aaa7a88 449 Gene3D G3DSA:1.25.40.10 309 412 5.6E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS02990 67c82e7786b0f84cf0273e1f3aaa7a88 449 Gene3D G3DSA:1.25.40.10 216 308 1.1E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS02990 67c82e7786b0f84cf0273e1f3aaa7a88 449 SUPERFAMILY SSF48452 217 322 3.96E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS12365 86c39ff8553f88aed1c6caea178f2ed5 136 SUPERFAMILY SSF55298 1 126 1.37E-25 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS12365 86c39ff8553f88aed1c6caea178f2ed5 136 Pfam PF01042 Endoribonuclease L-PSP 17 124 2.0E-14 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS12365 86c39ff8553f88aed1c6caea178f2ed5 136 Gene3D G3DSA:3.30.1330.40 1 127 1.8E-32 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS12365 86c39ff8553f88aed1c6caea178f2ed5 136 PANTHER PTHR11803:SF7 4 127 1.1E-35 T 23-04-2016 DC74_RS12365 86c39ff8553f88aed1c6caea178f2ed5 136 PANTHER PTHR11803 4 127 1.1E-35 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS34430 03efe88d2f2b9bf4f2887b11410f9fd0 462 PANTHER PTHR12526:SF374 341 424 1.9E-17 T 23-04-2016 DC74_RS34430 03efe88d2f2b9bf4f2887b11410f9fd0 462 PANTHER PTHR12526:SF374 56 294 1.9E-17 T 23-04-2016 DC74_RS34430 03efe88d2f2b9bf4f2887b11410f9fd0 462 PANTHER PTHR12526 341 424 1.9E-17 T 23-04-2016 DC74_RS34430 03efe88d2f2b9bf4f2887b11410f9fd0 462 PANTHER PTHR12526 56 294 1.9E-17 T 23-04-2016 DC74_RS34430 03efe88d2f2b9bf4f2887b11410f9fd0 462 Pfam PF13692 Glycosyl transferases group 1 160 285 7.3E-16 T 23-04-2016 DC74_RS34430 03efe88d2f2b9bf4f2887b11410f9fd0 462 Gene3D G3DSA:3.40.50.2000 155 280 2.8E-13 T 23-04-2016 DC74_RS34430 03efe88d2f2b9bf4f2887b11410f9fd0 462 SUPERFAMILY SSF53756 53 281 3.92E-30 T 23-04-2016 DC74_RS22315 9d59d04315c24400b957edd5f52d36fe 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 1.8E-26 T 23-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22315 9d59d04315c24400b957edd5f52d36fe 78 Pfam PF00830 Ribosomal L28 family 4 60 1.6E-24 T 23-04-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 DC74_RS22315 9d59d04315c24400b957edd5f52d36fe 78 SUPERFAMILY SSF143800 2 77 6.87E-26 T 23-04-2016 DC74_RS22315 9d59d04315c24400b957edd5f52d36fe 78 Gene3D G3DSA:2.30.170.40 2 78 1.8E-31 T 23-04-2016 DC74_RS22315 9d59d04315c24400b957edd5f52d36fe 78 PANTHER PTHR13528 1 74 2.8E-28 T 23-04-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 DC74_RS22315 9d59d04315c24400b957edd5f52d36fe 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 71 20.128 T 23-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS37825 398fb941f261a3e98d3673ff0195fad3 539 Gene3D G3DSA:3.40.50.300 122 235 2.4E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37825 398fb941f261a3e98d3673ff0195fad3 539 Gene3D G3DSA:3.40.50.300 3 90 2.4E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37825 398fb941f261a3e98d3673ff0195fad3 539 SUPERFAMILY SSF52540 347 525 9.94E-32 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37825 398fb941f261a3e98d3673ff0195fad3 539 SUPERFAMILY SSF52540 16 235 2.45E-37 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37825 398fb941f261a3e98d3673ff0195fad3 539 SMART SM00382 29 236 2.0E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS37825 398fb941f261a3e98d3673ff0195fad3 539 SMART SM00382 356 520 7.3E-7 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS37825 398fb941f261a3e98d3673ff0195fad3 539 PANTHER PTHR19211 16 524 2.8E-103 T 23-04-2016 DC74_RS37825 398fb941f261a3e98d3673ff0195fad3 539 Pfam PF00005 ABC transporter 348 475 4.6E-13 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS37825 398fb941f261a3e98d3673ff0195fad3 539 Pfam PF00005 ABC transporter 20 191 2.4E-19 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS37825 398fb941f261a3e98d3673ff0195fad3 539 Gene3D G3DSA:3.40.50.300 347 525 3.0E-29 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16065 0418caca189752d92850da961ad31811 609 PANTHER PTHR33121 324 603 2.5E-83 T 23-04-2016 DC74_RS16065 0418caca189752d92850da961ad31811 609 PANTHER PTHR33121:SF13 324 603 2.5E-83 T 23-04-2016 DC74_RS16065 0418caca189752d92850da961ad31811 609 Pfam PF00990 Diguanylate cyclase, GGDEF domain 163 330 5.1E-39 T 23-04-2016 IPR000160 GGDEF domain DC74_RS16065 0418caca189752d92850da961ad31811 609 Pfam PF00563 EAL domain 352 592 1.7E-68 T 23-04-2016 IPR001633 EAL domain DC74_RS16065 0418caca189752d92850da961ad31811 609 Pfam PF08448 PAS fold 44 152 2.6E-9 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS16065 0418caca189752d92850da961ad31811 609 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 159 333 3.1E-31 T 23-04-2016 IPR000160 GGDEF domain DC74_RS16065 0418caca189752d92850da961ad31811 609 Gene3D G3DSA:3.20.20.450 349 603 3.1E-105 T 23-04-2016 IPR001633 EAL domain DC74_RS16065 0418caca189752d92850da961ad31811 609 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 35 154 6.3E-14 T 23-04-2016 IPR000014 PAS domain DC74_RS16065 0418caca189752d92850da961ad31811 609 SMART SM00267 151 335 4.9E-47 T 23-04-2016 IPR000160 GGDEF domain DC74_RS16065 0418caca189752d92850da961ad31811 609 SUPERFAMILY SSF55073 168 337 1.65E-38 T 23-04-2016 IPR029787 Nucleotide cyclase DC74_RS16065 0418caca189752d92850da961ad31811 609 SUPERFAMILY SSF55785 32 133 1.33E-13 T 23-04-2016 IPR000014 PAS domain DC74_RS16065 0418caca189752d92850da961ad31811 609 SMART SM00052 345 597 3.8E-102 T 23-04-2016 IPR001633 EAL domain DC74_RS16065 0418caca189752d92850da961ad31811 609 SMART SM00091 35 101 0.0012 T 23-04-2016 IPR000014 PAS domain DC74_RS16065 0418caca189752d92850da961ad31811 609 Gene3D G3DSA:3.30.450.20 34 149 8.5E-15 T 23-04-2016 DC74_RS16065 0418caca189752d92850da961ad31811 609 SUPERFAMILY SSF141868 352 602 9.55E-83 T 23-04-2016 IPR001633 EAL domain DC74_RS16065 0418caca189752d92850da961ad31811 609 Gene3D G3DSA:3.30.70.270 163 340 2.8E-50 T 23-04-2016 DC74_RS32995 d3c9a67894322dd37c9898c45594191b 513 Gene3D G3DSA:1.20.1250.20 293 463 1.1E-14 T 23-04-2016 DC74_RS32995 d3c9a67894322dd37c9898c45594191b 513 SUPERFAMILY SSF103473 11 210 3.92E-62 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS32995 d3c9a67894322dd37c9898c45594191b 513 SUPERFAMILY SSF103473 280 463 3.92E-62 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS32995 d3c9a67894322dd37c9898c45594191b 513 Gene3D G3DSA:1.20.1250.20 27 206 3.3E-32 T 23-04-2016 DC74_RS32995 d3c9a67894322dd37c9898c45594191b 513 PANTHER PTHR23508 17 228 8.0E-181 T 23-04-2016 DC74_RS32995 d3c9a67894322dd37c9898c45594191b 513 PANTHER PTHR23508 280 476 8.0E-181 T 23-04-2016 DC74_RS32995 d3c9a67894322dd37c9898c45594191b 513 PANTHER PTHR23508:SF3 17 228 8.0E-181 T 23-04-2016 DC74_RS32995 d3c9a67894322dd37c9898c45594191b 513 PANTHER PTHR23508:SF3 280 476 8.0E-181 T 23-04-2016 DC74_RS32995 d3c9a67894322dd37c9898c45594191b 513 Pfam PF07690 Major Facilitator Superfamily 33 307 8.3E-24 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS25950 6b92e9d0ec09cdef58d3a9cfb82ef97d 286 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 DC74_RS25950 6b92e9d0ec09cdef58d3a9cfb82ef97d 286 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 271 1.3E-81 T 23-04-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614|UniPathway: UPA00077 DC74_RS25950 6b92e9d0ec09cdef58d3a9cfb82ef97d 286 PANTHER PTHR20941:SF8 1 277 1.5E-185 T 23-04-2016 DC74_RS25950 6b92e9d0ec09cdef58d3a9cfb82ef97d 286 SUPERFAMILY SSF51717 5 276 2.62E-81 T 23-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 DC74_RS25950 6b92e9d0ec09cdef58d3a9cfb82ef97d 286 Gene3D G3DSA:3.20.20.20 12 274 5.9E-85 T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 DC74_RS25950 6b92e9d0ec09cdef58d3a9cfb82ef97d 286 PANTHER PTHR20941 1 277 1.5E-185 T 23-04-2016 DC74_RS25950 6b92e9d0ec09cdef58d3a9cfb82ef97d 286 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 DC74_RS25950 6b92e9d0ec09cdef58d3a9cfb82ef97d 286 Pfam PF00809 Pterin binding enzyme 17 257 1.5E-64 T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 Gene3D G3DSA:3.40.50.300 115 186 3.9E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 Gene3D G3DSA:3.40.50.300 1 74 3.9E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 SUPERFAMILY SSF46894 841 902 1.09E-15 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 PANTHER PTHR16305 838 873 5.6E-55 T 23-04-2016 DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 PANTHER PTHR16305 1 429 5.6E-55 T 23-04-2016 DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 Pfam PF13191 AAA ATPase domain 2 161 1.8E-18 T 23-04-2016 DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 SMART SM00421 848 905 2.6E-18 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 Pfam PF00196 Bacterial regulatory proteins, luxR family 850 901 7.4E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 SUPERFAMILY SSF48452 543 689 2.62E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 Gene3D G3DSA:1.10.10.10 845 901 5.4E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 865 881 7.3E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 881 893 7.3E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 851 865 7.3E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 SUPERFAMILY SSF52540 2 65 4.11E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 SUPERFAMILY SSF52540 113 188 4.11E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 Gene3D G3DSA:1.25.40.10 585 825 1.2E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS04880 72861fbd0e4a2b6ab453025bd54934bc 911 Gene3D G3DSA:1.25.40.10 360 400 1.2E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS13590 fddac6e05ddb60f09f3397d13239a936 478 Pfam PF07690 Major Facilitator Superfamily 29 421 6.2E-47 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS13590 fddac6e05ddb60f09f3397d13239a936 478 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 435 2.0E-73 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS13590 fddac6e05ddb60f09f3397d13239a936 478 SUPERFAMILY SSF103473 259 472 1.96E-66 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS13590 fddac6e05ddb60f09f3397d13239a936 478 SUPERFAMILY SSF103473 16 208 1.96E-66 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS13590 fddac6e05ddb60f09f3397d13239a936 478 Gene3D G3DSA:1.20.1250.20 22 208 2.0E-28 T 23-04-2016 DC74_RS13590 fddac6e05ddb60f09f3397d13239a936 478 PANTHER PTHR23501 14 472 1.1E-173 T 23-04-2016 DC74_RS13590 fddac6e05ddb60f09f3397d13239a936 478 ProSitePatterns PS00216 Sugar transport proteins signature 1. 78 94 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS13590 fddac6e05ddb60f09f3397d13239a936 478 Gene3D G3DSA:1.20.1250.20 281 472 1.0E-19 T 23-04-2016 DC74_RS13590 fddac6e05ddb60f09f3397d13239a936 478 PANTHER PTHR23501:SF76 14 472 1.1E-173 T 23-04-2016 DC74_RS32635 855313217f7a34dcfaa2adc6e5682da2 830 SUPERFAMILY SSF52009 719 812 4.58E-8 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS32635 855313217f7a34dcfaa2adc6e5682da2 830 PANTHER PTHR11241 1 169 8.3E-36 T 23-04-2016 DC74_RS32635 855313217f7a34dcfaa2adc6e5682da2 830 PANTHER PTHR11241:SF1 1 169 8.3E-36 T 23-04-2016 DC74_RS32635 855313217f7a34dcfaa2adc6e5682da2 830 Gene3D G3DSA:3.30.1490.20 186 355 1.8E-28 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS32635 855313217f7a34dcfaa2adc6e5682da2 830 Pfam PF00391 PEP-utilising enzyme, mobile domain 766 810 4.9E-6 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS32635 855313217f7a34dcfaa2adc6e5682da2 830 Gene3D G3DSA:3.30.470.20 356 457 6.8E-12 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS32635 855313217f7a34dcfaa2adc6e5682da2 830 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 191 397 2.7E-28 T 23-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 DC74_RS32635 855313217f7a34dcfaa2adc6e5682da2 830 SUPERFAMILY SSF51283 1 168 1.45E-33 T 23-04-2016 IPR029054 dUTPase-like DC74_RS32635 855313217f7a34dcfaa2adc6e5682da2 830 Gene3D G3DSA:2.70.40.10 1 168 1.5E-33 T 23-04-2016 IPR029054 dUTPase-like DC74_RS32635 855313217f7a34dcfaa2adc6e5682da2 830 SUPERFAMILY SSF56059 189 462 8.83E-36 T 23-04-2016 DC74_RS32635 855313217f7a34dcfaa2adc6e5682da2 830 Gene3D G3DSA:3.50.30.10 752 822 4.6E-7 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS09645 0f0fc3cce3f1e9e57945b0a285f8b9a8 379 SUPERFAMILY SSF53756 2 363 1.32E-83 T 23-04-2016 DC74_RS09645 0f0fc3cce3f1e9e57945b0a285f8b9a8 379 Pfam PF13439 Glycosyltransferase Family 4 14 173 2.9E-34 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain DC74_RS09645 0f0fc3cce3f1e9e57945b0a285f8b9a8 379 PANTHER PTHR12526 1 363 2.6E-208 T 23-04-2016 DC74_RS09645 0f0fc3cce3f1e9e57945b0a285f8b9a8 379 PANTHER PTHR12526:SF368 1 363 2.6E-208 T 23-04-2016 DC74_RS09645 0f0fc3cce3f1e9e57945b0a285f8b9a8 379 Gene3D G3DSA:3.40.50.2000 185 340 1.2E-25 T 23-04-2016 DC74_RS09645 0f0fc3cce3f1e9e57945b0a285f8b9a8 379 Pfam PF13692 Glycosyl transferases group 1 187 327 3.3E-29 T 23-04-2016 DC74_RS02410 1d5522de1a57f7ad8e5ef67e11323152 249 SUPERFAMILY SSF46955 17 116 9.16E-8 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS02410 1d5522de1a57f7ad8e5ef67e11323152 249 Pfam PF13411 MerR HTH family regulatory protein 133 199 6.0E-16 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS02410 1d5522de1a57f7ad8e5ef67e11323152 249 Gene3D G3DSA:1.10.1660.10 16 120 3.6E-11 T 23-04-2016 DC74_RS02410 1d5522de1a57f7ad8e5ef67e11323152 249 Gene3D G3DSA:1.10.1660.10 133 243 3.9E-18 T 23-04-2016 DC74_RS02410 1d5522de1a57f7ad8e5ef67e11323152 249 PANTHER PTHR30204 125 223 3.9E-12 T 23-04-2016 DC74_RS02410 1d5522de1a57f7ad8e5ef67e11323152 249 SUPERFAMILY SSF46955 133 239 2.15E-15 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS02410 1d5522de1a57f7ad8e5ef67e11323152 249 Pfam PF00376 MerR family regulatory protein 17 51 5.0E-7 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS02410 1d5522de1a57f7ad8e5ef67e11323152 249 SMART SM00422 13 79 0.026 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS02410 1d5522de1a57f7ad8e5ef67e11323152 249 SMART SM00422 133 202 4.6E-6 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS11280 993556074d806f4b7e7d83f821b0fa40 239 SUPERFAMILY SSF53955 131 233 2.7E-14 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS11280 993556074d806f4b7e7d83f821b0fa40 239 Pfam PF01464 Transglycosylase SLT domain 164 236 1.1E-8 T 23-04-2016 IPR008258 Transglycosylase SLT domain 1 DC74_RS11280 993556074d806f4b7e7d83f821b0fa40 239 Gene3D G3DSA:1.10.530.10 160 236 1.1E-9 T 23-04-2016 DC74_RS02865 5770befe8cf30e9686f1fb850a65aa85 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.3E-13 T 23-04-2016 DC74_RS02865 5770befe8cf30e9686f1fb850a65aa85 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 1.3E-13 T 23-04-2016 DC74_RS02865 5770befe8cf30e9686f1fb850a65aa85 375 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 1.3E-13 T 23-04-2016 DC74_RS02865 5770befe8cf30e9686f1fb850a65aa85 375 SUPERFAMILY SSF51905 6 171 1.3E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02865 5770befe8cf30e9686f1fb850a65aa85 375 SUPERFAMILY SSF51905 276 362 1.3E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02865 5770befe8cf30e9686f1fb850a65aa85 375 Gene3D G3DSA:3.50.50.60 276 354 1.0E-38 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02865 5770befe8cf30e9686f1fb850a65aa85 375 Gene3D G3DSA:3.50.50.60 6 176 1.0E-38 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02865 5770befe8cf30e9686f1fb850a65aa85 375 PANTHER PTHR13789:SF174 5 367 1.5E-106 T 23-04-2016 DC74_RS02865 5770befe8cf30e9686f1fb850a65aa85 375 PANTHER PTHR13789 5 367 1.5E-106 T 23-04-2016 DC74_RS02865 5770befe8cf30e9686f1fb850a65aa85 375 Pfam PF01494 FAD binding domain 7 326 7.2E-14 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS02860 e8cdda3da6f9b3c9ef5cf93ac43512ba 155 SUPERFAMILY SSF46785 12 132 3.15E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02860 e8cdda3da6f9b3c9ef5cf93ac43512ba 155 PANTHER PTHR33164:SF15 15 131 3.3E-43 T 23-04-2016 DC74_RS02860 e8cdda3da6f9b3c9ef5cf93ac43512ba 155 SMART SM00347 32 137 1.3E-12 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS02860 e8cdda3da6f9b3c9ef5cf93ac43512ba 155 PANTHER PTHR33164 15 131 3.3E-43 T 23-04-2016 DC74_RS02860 e8cdda3da6f9b3c9ef5cf93ac43512ba 155 Gene3D G3DSA:1.10.10.10 5 132 6.9E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02860 e8cdda3da6f9b3c9ef5cf93ac43512ba 155 Pfam PF01047 MarR family 60 101 4.4E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS29405 8240b34239c7f2ae7b6c3a10a0b7a6cf 499 Gene3D G3DSA:3.40.605.10 5 261 6.3E-84 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS29405 8240b34239c7f2ae7b6c3a10a0b7a6cf 499 PANTHER PTHR11699:SF189 1 498 2.1E-270 T 23-04-2016 DC74_RS29405 8240b34239c7f2ae7b6c3a10a0b7a6cf 499 PANTHER PTHR11699 1 498 2.1E-270 T 23-04-2016 DC74_RS29405 8240b34239c7f2ae7b6c3a10a0b7a6cf 499 Pfam PF00171 Aldehyde dehydrogenase family 18 479 1.9E-139 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS29405 8240b34239c7f2ae7b6c3a10a0b7a6cf 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS29405 8240b34239c7f2ae7b6c3a10a0b7a6cf 499 Gene3D G3DSA:3.40.309.10 262 444 1.1E-63 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS29405 8240b34239c7f2ae7b6c3a10a0b7a6cf 499 SUPERFAMILY SSF53720 2 484 2.23E-148 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS29405 8240b34239c7f2ae7b6c3a10a0b7a6cf 499 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 6 483 1.5E-193 T 23-04-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 DC74_RS30305 4a50e478a50ae9b3ef60571d1894be4c 207 Gene3D G3DSA:3.40.50.1950 1 189 3.4E-80 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS30305 4a50e478a50ae9b3ef60571d1894be4c 207 Pfam PF02441 Flavoprotein 1 128 3.5E-25 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS30305 4a50e478a50ae9b3ef60571d1894be4c 207 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 183 1.1E-76 T 23-04-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 DC74_RS30305 4a50e478a50ae9b3ef60571d1894be4c 207 Hamap MF_01986 Probable UbiX-like flavin prenyltransferase. 1 189 48.501 T 23-04-2016 IPR032901 Probable UbiX-like flavin prenyltransferase DC74_RS30305 4a50e478a50ae9b3ef60571d1894be4c 207 PANTHER PTHR30108:SF2 1 185 1.9E-87 T 23-04-2016 DC74_RS30305 4a50e478a50ae9b3ef60571d1894be4c 207 PANTHER PTHR30108 1 185 1.9E-87 T 23-04-2016 DC74_RS30305 4a50e478a50ae9b3ef60571d1894be4c 207 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 185 37.019 T 23-04-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 DC74_RS30305 4a50e478a50ae9b3ef60571d1894be4c 207 SUPERFAMILY SSF52507 1 185 9.81E-62 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS37565 6133a28986ca01e0987dedc9d8d952fa 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 25 274 6.5E-56 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS37565 6133a28986ca01e0987dedc9d8d952fa 275 SUPERFAMILY SSF52096 15 274 7.23E-77 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS37565 6133a28986ca01e0987dedc9d8d952fa 275 Gene3D G3DSA:3.90.226.10 17 273 1.7E-77 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS37565 6133a28986ca01e0987dedc9d8d952fa 275 PANTHER PTHR11941 3 272 2.2E-81 T 23-04-2016 DC74_RS37565 6133a28986ca01e0987dedc9d8d952fa 275 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 117 137 - T 23-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 DC74_RS23000 cd6741103b00218f192bb910657fbe4f 342 SUPERFAMILY SSF52540 91 326 1.7E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23000 cd6741103b00218f192bb910657fbe4f 342 Gene3D G3DSA:3.40.50.300 88 218 2.2E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23000 cd6741103b00218f192bb910657fbe4f 342 Pfam PF05621 Bacterial TniB protein 62 321 3.7E-30 T 23-04-2016 IPR008868 Bacterial TniB DC74_RS19665 b5da76e935d1b4fbebc249c074e24455 68 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 11 58 1.2E-8 T 23-04-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 DC74_RS19665 b5da76e935d1b4fbebc249c074e24455 68 SUPERFAMILY SSF46955 11 59 2.61E-11 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS19665 b5da76e935d1b4fbebc249c074e24455 68 Gene3D G3DSA:1.10.1660.10 11 57 5.4E-7 T 23-04-2016 DC74_RS19665 b5da76e935d1b4fbebc249c074e24455 68 Pfam PF12728 Helix-turn-helix domain 11 59 1.3E-11 T 23-04-2016 DC74_RS32575 5e6af482aa56eb809521666282e4f23d 335 Gene3D G3DSA:3.40.50.2300 174 333 3.7E-43 T 23-04-2016 DC74_RS32575 5e6af482aa56eb809521666282e4f23d 335 SMART SM00354 6 78 5.0E-24 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS32575 5e6af482aa56eb809521666282e4f23d 335 Gene3D G3DSA:1.10.260.40 7 60 1.9E-22 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS32575 5e6af482aa56eb809521666282e4f23d 335 Gene3D G3DSA:3.40.50.2300 61 173 1.1E-26 T 23-04-2016 DC74_RS32575 5e6af482aa56eb809521666282e4f23d 335 SUPERFAMILY SSF47413 6 66 5.88E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS32575 5e6af482aa56eb809521666282e4f23d 335 PANTHER PTHR30146:SF47 6 334 3.9E-130 T 23-04-2016 DC74_RS32575 5e6af482aa56eb809521666282e4f23d 335 PANTHER PTHR30146 6 334 3.9E-130 T 23-04-2016 DC74_RS32575 5e6af482aa56eb809521666282e4f23d 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 2.1E-12 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS32575 5e6af482aa56eb809521666282e4f23d 335 Pfam PF13377 Periplasmic binding protein-like domain 173 331 3.1E-33 T 23-04-2016 DC74_RS32575 5e6af482aa56eb809521666282e4f23d 335 SUPERFAMILY SSF53822 65 325 3.62E-49 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS27435 20b1b64bbc09eb13af6aac22f1493d0e 238 Pfam PF09335 SNARE associated Golgi protein 47 177 3.7E-20 T 23-04-2016 IPR032816 SNARE associated Golgi protein DC74_RS27435 20b1b64bbc09eb13af6aac22f1493d0e 238 PANTHER PTHR30353:SF0 1 238 1.3E-73 T 23-04-2016 DC74_RS27435 20b1b64bbc09eb13af6aac22f1493d0e 238 PANTHER PTHR30353 1 238 1.3E-73 T 23-04-2016 IPR032818 DedA family DC74_RS37690 e5a3a431e270e6b81d1fa167cfc1b911 293 PANTHER PTHR10992 9 68 5.9E-48 T 23-04-2016 DC74_RS37690 e5a3a431e270e6b81d1fa167cfc1b911 293 PANTHER PTHR10992 94 274 5.9E-48 T 23-04-2016 DC74_RS37690 e5a3a431e270e6b81d1fa167cfc1b911 293 Pfam PF00561 alpha/beta hydrolase fold 24 179 4.3E-14 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS37690 e5a3a431e270e6b81d1fa167cfc1b911 293 Gene3D G3DSA:3.40.50.1820 2 289 2.3E-62 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS37690 e5a3a431e270e6b81d1fa167cfc1b911 293 PANTHER PTHR10992:SF851 9 68 5.9E-48 T 23-04-2016 DC74_RS37690 e5a3a431e270e6b81d1fa167cfc1b911 293 PANTHER PTHR10992:SF851 94 274 5.9E-48 T 23-04-2016 DC74_RS37690 e5a3a431e270e6b81d1fa167cfc1b911 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 238 252 3.3E-8 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS37690 e5a3a431e270e6b81d1fa167cfc1b911 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 3.3E-8 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS37690 e5a3a431e270e6b81d1fa167cfc1b911 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 145 3.3E-8 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS37690 e5a3a431e270e6b81d1fa167cfc1b911 293 SUPERFAMILY SSF53474 6 289 7.69E-59 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31580 27a3bc98259c6e8b8a829828406cf37b 326 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 32 321 6.1E-74 T 23-04-2016 IPR014146 DNA ligase D, ligase domain DC74_RS31580 27a3bc98259c6e8b8a829828406cf37b 326 PANTHER PTHR10459:SF61 18 321 1.1E-36 T 23-04-2016 DC74_RS31580 27a3bc98259c6e8b8a829828406cf37b 326 Gene3D G3DSA:3.30.470.30 45 157 6.0E-23 T 23-04-2016 DC74_RS31580 27a3bc98259c6e8b8a829828406cf37b 326 PANTHER PTHR10459 18 321 1.1E-36 T 23-04-2016 DC74_RS31580 27a3bc98259c6e8b8a829828406cf37b 326 SUPERFAMILY SSF50249 213 321 3.3E-23 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS31580 27a3bc98259c6e8b8a829828406cf37b 326 Gene3D G3DSA:2.40.50.140 214 322 7.0E-32 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS31580 27a3bc98259c6e8b8a829828406cf37b 326 SUPERFAMILY SSF56091 16 211 4.32E-40 T 23-04-2016 DC74_RS31580 27a3bc98259c6e8b8a829828406cf37b 326 Pfam PF01068 ATP dependent DNA ligase domain 32 211 3.4E-25 T 23-04-2016 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 Reactome: REACT_216 DC74_RS31580 27a3bc98259c6e8b8a829828406cf37b 326 Gene3D G3DSA:3.30.1490.70 168 212 3.9E-19 T 23-04-2016 DC74_RS31580 27a3bc98259c6e8b8a829828406cf37b 326 Gene3D G3DSA:3.30.1490.70 16 44 3.9E-19 T 23-04-2016 DC74_RS31580 27a3bc98259c6e8b8a829828406cf37b 326 Pfam PF04679 ATP dependent DNA ligase C terminal region 232 321 8.3E-20 T 23-04-2016 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 DC74_RS07350 7237c18e851e3a348b04f79af2c6fec2 135 Gene3D G3DSA:2.40.50.100 65 128 3.2E-19 T 23-04-2016 DC74_RS07350 7237c18e851e3a348b04f79af2c6fec2 135 Pfam PF03459 TOBE domain 66 128 2.0E-14 T 23-04-2016 IPR005116 Transport-associated OB, type 1 DC74_RS07350 7237c18e851e3a348b04f79af2c6fec2 135 SUPERFAMILY SSF50331 10 128 1.82E-16 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal DC74_RS07350 7237c18e851e3a348b04f79af2c6fec2 135 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 65 129 8.1E-16 T 23-04-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 DC74_RS07350 7237c18e851e3a348b04f79af2c6fec2 135 Pfam PF12728 Helix-turn-helix domain 4 53 6.0E-7 T 23-04-2016 DC74_RS07350 7237c18e851e3a348b04f79af2c6fec2 135 PANTHER PTHR30432 3 130 9.6E-13 T 23-04-2016 DC74_RS07350 7237c18e851e3a348b04f79af2c6fec2 135 Gene3D G3DSA:1.10.1660.10 4 40 3.2E-5 T 23-04-2016 DC74_RS38290 fbf597a020f0c3a1002d93e9ba0f4c51 275 PANTHER PTHR30465:SF2 1 274 3.7E-79 T 23-04-2016 DC74_RS38290 fbf597a020f0c3a1002d93e9ba0f4c51 275 Gene3D G3DSA:1.10.3720.10 66 274 1.5E-22 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38290 fbf597a020f0c3a1002d93e9ba0f4c51 275 SUPERFAMILY SSF161098 71 258 9.94E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38290 fbf597a020f0c3a1002d93e9ba0f4c51 275 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 4 52 1.0E-8 T 23-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain DC74_RS38290 fbf597a020f0c3a1002d93e9ba0f4c51 275 PANTHER PTHR30465 1 274 3.7E-79 T 23-04-2016 DC74_RS38290 fbf597a020f0c3a1002d93e9ba0f4c51 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 274 1.0E-22 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS11740 303c4edc2f532b461669694afb2ea5b2 273 PANTHER PTHR30363 32 242 4.7E-39 T 23-04-2016 DC74_RS11740 303c4edc2f532b461669694afb2ea5b2 273 Pfam PF01022 Bacterial regulatory protein, arsR family 32 76 5.0E-6 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS11740 303c4edc2f532b461669694afb2ea5b2 273 SUPERFAMILY SSF46785 32 223 1.57E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11740 303c4edc2f532b461669694afb2ea5b2 273 Gene3D G3DSA:1.10.10.10 33 122 2.2E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11740 303c4edc2f532b461669694afb2ea5b2 273 PANTHER PTHR30363:SF17 32 242 4.7E-39 T 23-04-2016 DC74_RS20530 21ccf8dbc8c6501f5e70a9fa940984c9 396 SUPERFAMILY SSF103473 11 386 2.49E-55 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS20530 21ccf8dbc8c6501f5e70a9fa940984c9 396 Gene3D G3DSA:1.20.1250.20 207 389 2.0E-16 T 23-04-2016 DC74_RS20530 21ccf8dbc8c6501f5e70a9fa940984c9 396 PANTHER PTHR23501:SF4 12 392 6.7E-92 T 23-04-2016 DC74_RS20530 21ccf8dbc8c6501f5e70a9fa940984c9 396 Gene3D G3DSA:1.20.1250.20 12 190 2.0E-26 T 23-04-2016 DC74_RS20530 21ccf8dbc8c6501f5e70a9fa940984c9 396 Pfam PF07690 Major Facilitator Superfamily 28 340 4.1E-33 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS20530 21ccf8dbc8c6501f5e70a9fa940984c9 396 PANTHER PTHR23501 12 392 6.7E-92 T 23-04-2016 DC74_RS25080 829bfaa2de4819318802a35808240729 208 PANTHER PTHR30055 23 208 6.7E-45 T 23-04-2016 DC74_RS25080 829bfaa2de4819318802a35808240729 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 40 85 1.2E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS25080 829bfaa2de4819318802a35808240729 208 SUPERFAMILY SSF46689 26 106 2.17E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS25080 829bfaa2de4819318802a35808240729 208 PANTHER PTHR30055:SF19 23 208 6.7E-45 T 23-04-2016 DC74_RS25080 829bfaa2de4819318802a35808240729 208 SUPERFAMILY SSF48498 105 208 5.15E-11 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS25080 829bfaa2de4819318802a35808240729 208 Gene3D G3DSA:1.10.357.10 28 207 6.4E-42 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS25080 829bfaa2de4819318802a35808240729 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 53 3.0E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS25080 829bfaa2de4819318802a35808240729 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 60 83 3.0E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01705 2ca48350f23cdf30c69e09f6bd51bc5e 122 Gene3D G3DSA:3.10.180.10 3 117 4.8E-16 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS01705 2ca48350f23cdf30c69e09f6bd51bc5e 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 115 8.1E-7 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS01705 2ca48350f23cdf30c69e09f6bd51bc5e 122 SUPERFAMILY SSF54593 3 119 3.49E-19 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS01705 2ca48350f23cdf30c69e09f6bd51bc5e 122 PANTHER PTHR35908 1 118 1.6E-33 T 23-04-2016 DC74_RS01705 2ca48350f23cdf30c69e09f6bd51bc5e 122 PANTHER PTHR35908:SF1 1 118 1.6E-33 T 23-04-2016 DC74_RS13640 e5ab05eecb37e4e70ed8c5ec16cf26ce 270 PANTHER PTHR10108:SF752 1 181 1.7E-50 T 23-04-2016 DC74_RS13640 e5ab05eecb37e4e70ed8c5ec16cf26ce 270 SUPERFAMILY SSF53335 8 236 3.41E-43 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS13640 e5ab05eecb37e4e70ed8c5ec16cf26ce 270 Gene3D G3DSA:3.40.50.150 7 236 1.0E-50 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS13640 e5ab05eecb37e4e70ed8c5ec16cf26ce 270 Pfam PF08241 Methyltransferase domain 18 121 1.7E-22 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS13640 e5ab05eecb37e4e70ed8c5ec16cf26ce 270 PANTHER PTHR10108 1 181 1.7E-50 T 23-04-2016 DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 SUPERFAMILY SSF47413 2 60 9.12E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 SMART SM00354 2 72 4.7E-20 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 Pfam PF13377 Periplasmic binding protein-like domain 203 361 4.7E-35 T 23-04-2016 DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 PANTHER PTHR30146 192 363 1.3E-102 T 23-04-2016 DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 PANTHER PTHR30146 1 172 1.3E-102 T 23-04-2016 DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 Gene3D G3DSA:3.40.50.2300 63 206 6.8E-38 T 23-04-2016 DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 SUPERFAMILY SSF53822 62 363 1.71E-55 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 47 2.1E-15 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 PANTHER PTHR30146:SF48 192 363 1.3E-102 T 23-04-2016 DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 PANTHER PTHR30146:SF48 1 172 1.3E-102 T 23-04-2016 DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 Gene3D G3DSA:1.10.260.40 3 62 3.3E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS15790 900154a47d50f48ee696746d4a24fa47 392 Gene3D G3DSA:3.40.50.2300 207 340 4.1E-54 T 23-04-2016 DC74_RS08210 8f5c98f4efae414d78b875644f8a0d15 319 Pfam PF12833 Helix-turn-helix domain 228 306 2.7E-20 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS08210 8f5c98f4efae414d78b875644f8a0d15 319 SUPERFAMILY SSF46689 210 256 1.26E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS08210 8f5c98f4efae414d78b875644f8a0d15 319 Pfam PF01965 DJ-1/PfpI family 4 165 2.8E-20 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS08210 8f5c98f4efae414d78b875644f8a0d15 319 Gene3D G3DSA:3.40.50.880 4 210 1.4E-48 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS08210 8f5c98f4efae414d78b875644f8a0d15 319 SUPERFAMILY SSF52317 4 187 1.37E-44 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS08210 8f5c98f4efae414d78b875644f8a0d15 319 PANTHER PTHR11019:SF68 4 313 1.9E-112 T 23-04-2016 DC74_RS08210 8f5c98f4efae414d78b875644f8a0d15 319 SMART SM00342 222 305 1.6E-23 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS08210 8f5c98f4efae414d78b875644f8a0d15 319 Gene3D G3DSA:1.10.10.60 260 308 1.2E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS08210 8f5c98f4efae414d78b875644f8a0d15 319 Gene3D G3DSA:1.10.10.60 211 259 3.4E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS08210 8f5c98f4efae414d78b875644f8a0d15 319 SUPERFAMILY SSF46689 259 309 5.25E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS08210 8f5c98f4efae414d78b875644f8a0d15 319 PANTHER PTHR11019 4 313 1.9E-112 T 23-04-2016 DC74_RS37775 b67b4a882125b8601c3e8006205656ba 570 Gene3D G3DSA:3.40.50.1820 68 211 1.2E-45 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS37775 b67b4a882125b8601c3e8006205656ba 570 Gene3D G3DSA:3.40.50.1820 261 344 1.2E-45 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS37775 b67b4a882125b8601c3e8006205656ba 570 SUPERFAMILY SSF53474 69 343 4.45E-42 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS37775 b67b4a882125b8601c3e8006205656ba 570 SUPERFAMILY SSF49785 443 569 9.78E-14 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS37775 b67b4a882125b8601c3e8006205656ba 570 PANTHER PTHR11731 70 213 4.8E-12 T 23-04-2016 DC74_RS37775 b67b4a882125b8601c3e8006205656ba 570 Gene3D G3DSA:2.60.120.260 416 564 4.6E-12 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS37775 b67b4a882125b8601c3e8006205656ba 570 SMART SM00939 333 566 5.1E-7 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 DC74_RS37775 b67b4a882125b8601c3e8006205656ba 570 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 74 314 2.2E-28 T 23-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 DC74_RS37775 b67b4a882125b8601c3e8006205656ba 570 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 442 550 2.0E-12 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 Gene3D G3DSA:2.60.40.10 5 151 2.2E-51 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 PANTHER PTHR10357 632 725 0.0 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 PANTHER PTHR10357 1 601 0.0 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 SMART SM00642 177 557 2.0E-7 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 SUPERFAMILY SSF81296 5 147 2.52E-41 T 23-04-2016 IPR014756 Immunoglobulin E-set DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 SUPERFAMILY SSF51011 613 724 1.15E-21 T 23-04-2016 DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 Pfam PF00128 Alpha amylase, catalytic domain 188 276 1.3E-6 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 Gene3D G3DSA:3.20.20.80 152 598 4.2E-116 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 551 1.4E-269 T 23-04-2016 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 UniPathway: UPA00165 DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 7.7E-16 T 23-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 Gene3D G3DSA:2.60.40.1180 612 725 1.2E-30 T 23-04-2016 IPR013780 Glycosyl hydrolase, all-beta DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 PANTHER PTHR10357:SF74 632 725 0.0 T 23-04-2016 DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 PANTHER PTHR10357:SF74 1 601 0.0 T 23-04-2016 DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 SUPERFAMILY SSF51445 133 470 1.04E-131 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS29980 9fd6fa2cafeac9c53cc4cbbf99562074 727 SUPERFAMILY SSF51445 499 598 1.04E-131 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS35315 464f43dea4ad2ec88b175a8e2b0fe9e5 411 SUPERFAMILY SSF51905 2 161 1.4E-46 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35315 464f43dea4ad2ec88b175a8e2b0fe9e5 411 SUPERFAMILY SSF51905 268 354 1.4E-46 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35315 464f43dea4ad2ec88b175a8e2b0fe9e5 411 PANTHER PTHR13789:SF209 1 396 1.3E-114 T 23-04-2016 DC74_RS35315 464f43dea4ad2ec88b175a8e2b0fe9e5 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 2.9E-8 T 23-04-2016 DC74_RS35315 464f43dea4ad2ec88b175a8e2b0fe9e5 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 2.9E-8 T 23-04-2016 DC74_RS35315 464f43dea4ad2ec88b175a8e2b0fe9e5 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 140 155 2.9E-8 T 23-04-2016 DC74_RS35315 464f43dea4ad2ec88b175a8e2b0fe9e5 411 PANTHER PTHR13789 1 396 1.3E-114 T 23-04-2016 DC74_RS35315 464f43dea4ad2ec88b175a8e2b0fe9e5 411 Gene3D G3DSA:3.50.50.60 269 346 2.5E-34 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35315 464f43dea4ad2ec88b175a8e2b0fe9e5 411 Gene3D G3DSA:3.50.50.60 2 166 2.5E-34 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35315 464f43dea4ad2ec88b175a8e2b0fe9e5 411 Pfam PF01494 FAD binding domain 1 327 2.3E-46 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS24360 f164b1ab57005139405eada0243dcff2 377 Pfam PF00877 NlpC/P60 family 277 367 5.0E-25 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS24360 f164b1ab57005139405eada0243dcff2 377 Gene3D G3DSA:3.90.1720.10 262 366 6.0E-44 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS24360 f164b1ab57005139405eada0243dcff2 377 PANTHER PTHR21666 268 367 1.0E-37 T 23-04-2016 DC74_RS24360 f164b1ab57005139405eada0243dcff2 377 SUPERFAMILY SSF54001 262 368 2.94E-41 T 23-04-2016 DC74_RS38465 d2badd7df0e05383fbb4250f975b73a4 337 Gene3D G3DSA:3.40.50.300 14 262 8.6E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38465 d2badd7df0e05383fbb4250f975b73a4 337 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 325 2.0E-22 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS38465 d2badd7df0e05383fbb4250f975b73a4 337 SMART SM00382 42 238 1.1E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS38465 d2badd7df0e05383fbb4250f975b73a4 337 PANTHER PTHR24220:SF535 17 309 3.2E-111 T 23-04-2016 DC74_RS38465 d2badd7df0e05383fbb4250f975b73a4 337 SUPERFAMILY SSF52540 14 261 7.66E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38465 d2badd7df0e05383fbb4250f975b73a4 337 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 304 5.2E-20 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS38465 d2badd7df0e05383fbb4250f975b73a4 337 PANTHER PTHR24220 17 309 3.2E-111 T 23-04-2016 DC74_RS38465 d2badd7df0e05383fbb4250f975b73a4 337 Pfam PF00005 ABC transporter 33 188 1.1E-22 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS38465 d2badd7df0e05383fbb4250f975b73a4 337 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS06770 5702cc92fe97561b42974881371b1aba 239 PANTHER PTHR24094 61 238 4.6E-62 T 23-04-2016 DC74_RS06770 5702cc92fe97561b42974881371b1aba 239 Pfam PF07510 Protein of unknown function (DUF1524) 130 232 2.5E-6 T 23-04-2016 IPR011089 Domain of unknown function DUF1524 DC74_RS06770 5702cc92fe97561b42974881371b1aba 239 PANTHER PTHR24094:SF14 61 238 4.6E-62 T 23-04-2016 DC74_RS30970 cbccc5d03e7a5b8e187493226f558944 685 PANTHER PTHR31956:SF1 4 511 1.5E-181 T 23-04-2016 DC74_RS30970 cbccc5d03e7a5b8e187493226f558944 685 Pfam PF04185 Phosphoesterase family 44 428 3.4E-120 T 23-04-2016 IPR007312 Phosphoesterase GO:0016788 DC74_RS30970 cbccc5d03e7a5b8e187493226f558944 685 SUPERFAMILY SSF53649 144 257 1.18E-6 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS30970 cbccc5d03e7a5b8e187493226f558944 685 SUPERFAMILY SSF53649 308 431 1.18E-6 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS30970 cbccc5d03e7a5b8e187493226f558944 685 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 682 2.8E-268 T 23-04-2016 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 DC74_RS30970 cbccc5d03e7a5b8e187493226f558944 685 Pfam PF05506 Domain of unknown function (DUF756) 589 669 8.2E-18 T 23-04-2016 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 DC74_RS30970 cbccc5d03e7a5b8e187493226f558944 685 Pfam PF05506 Domain of unknown function (DUF756) 496 582 2.2E-18 T 23-04-2016 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 DC74_RS30970 cbccc5d03e7a5b8e187493226f558944 685 PANTHER PTHR31956 4 511 1.5E-181 T 23-04-2016 DC74_RS33205 960cd9359837354c3d57ee67adfe32f0 263 Gene3D G3DSA:3.40.50.300 52 260 1.2E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33205 960cd9359837354c3d57ee67adfe32f0 263 PANTHER PTHR24220 41 260 4.6E-89 T 23-04-2016 DC74_RS33205 960cd9359837354c3d57ee67adfe32f0 263 Pfam PF00005 ABC transporter 61 194 2.1E-16 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS33205 960cd9359837354c3d57ee67adfe32f0 263 PANTHER PTHR24220:SF117 41 260 4.6E-89 T 23-04-2016 DC74_RS33205 960cd9359837354c3d57ee67adfe32f0 263 SMART SM00382 69 243 2.1E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS33205 960cd9359837354c3d57ee67adfe32f0 263 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS33205 960cd9359837354c3d57ee67adfe32f0 263 SUPERFAMILY SSF52540 51 257 6.63E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21795 3f9c484ddb63823d06bee6ddb85adc2a 414 Gene3D G3DSA:3.40.640.10 74 318 2.6E-82 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS21795 3f9c484ddb63823d06bee6ddb85adc2a 414 Pfam PF00202 Aminotransferase class-III 31 413 2.2E-110 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS21795 3f9c484ddb63823d06bee6ddb85adc2a 414 Gene3D G3DSA:3.90.1150.10 17 73 4.8E-35 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS21795 3f9c484ddb63823d06bee6ddb85adc2a 414 Gene3D G3DSA:3.90.1150.10 323 413 4.8E-35 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS21795 3f9c484ddb63823d06bee6ddb85adc2a 414 SUPERFAMILY SSF53383 30 413 6.47E-115 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS21795 3f9c484ddb63823d06bee6ddb85adc2a 414 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 275 - T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS21795 3f9c484ddb63823d06bee6ddb85adc2a 414 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 21 413 2.6E-146 T 23-04-2016 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|UniPathway: UPA00098 DC74_RS21795 3f9c484ddb63823d06bee6ddb85adc2a 414 PANTHER PTHR11986 1 413 7.8E-199 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS21795 3f9c484ddb63823d06bee6ddb85adc2a 414 PANTHER PTHR11986:SF18 1 413 7.8E-199 T 23-04-2016 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|UniPathway: UPA00098 DC74_RS04565 eac6f855f20471ca5f794afe2c9ad4ee 390 PANTHER PTHR31686:SF2 26 389 1.9E-107 T 23-04-2016 DC74_RS04565 eac6f855f20471ca5f794afe2c9ad4ee 390 Pfam PF03595 Voltage-dependent anion channel 28 363 1.1E-69 T 23-04-2016 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 DC74_RS04565 eac6f855f20471ca5f794afe2c9ad4ee 390 PANTHER PTHR31686 26 389 1.9E-107 T 23-04-2016 DC74_RS38980 a5bdf5f537adaa811f46cb63191a271f 320 SUPERFAMILY SSF55729 29 308 5.29E-22 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS38980 a5bdf5f537adaa811f46cb63191a271f 320 Gene3D G3DSA:3.40.630.30 172 311 2.3E-15 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS38980 a5bdf5f537adaa811f46cb63191a271f 320 Pfam PF00583 Acetyltransferase (GNAT) family 230 302 1.9E-8 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS04470 dba4339d3a7992ce06d8cd74dd497ab4 263 PANTHER PTHR30007:SF0 1 260 2.0E-75 T 23-04-2016 DC74_RS04470 dba4339d3a7992ce06d8cd74dd497ab4 263 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 77 6.2E-22 T 23-04-2016 IPR025161 Putative transposase IS4/IS5 family DC74_RS04470 dba4339d3a7992ce06d8cd74dd497ab4 263 PANTHER PTHR30007 1 260 2.0E-75 T 23-04-2016 DC74_RS04470 dba4339d3a7992ce06d8cd74dd497ab4 263 Pfam PF01609 Transposase DDE domain 96 248 4.5E-17 T 23-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 DC74_RS15700 39e3930d9be85fcf8707c94f5755e721 333 Pfam PF04962 KduI/IolB family 44 307 1.0E-85 T 23-04-2016 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507|UniPathway: UPA00545 DC74_RS15700 39e3930d9be85fcf8707c94f5755e721 333 Gene3D G3DSA:2.60.120.10 51 155 3.9E-26 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS15700 39e3930d9be85fcf8707c94f5755e721 333 SUPERFAMILY SSF51182 51 292 1.51E-59 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS15700 39e3930d9be85fcf8707c94f5755e721 333 Gene3D G3DSA:2.60.120.10 156 313 5.1E-64 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS15700 39e3930d9be85fcf8707c94f5755e721 333 PANTHER PTHR39193:SF1 34 321 1.6E-112 T 23-04-2016 DC74_RS15700 39e3930d9be85fcf8707c94f5755e721 333 PANTHER PTHR39193 34 321 1.6E-112 T 23-04-2016 DC74_RS15700 39e3930d9be85fcf8707c94f5755e721 333 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 52 308 1.0E-81 T 23-04-2016 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30|UniPathway: UPA00076 DC74_RS00820 3037c344565afe4a9958cf6d272bfd0c 286 PANTHER PTHR14194:SF73 2 282 1.5E-78 T 23-04-2016 DC74_RS00820 3037c344565afe4a9958cf6d272bfd0c 286 Pfam PF13460 NAD(P)H-binding 6 142 2.8E-22 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00820 3037c344565afe4a9958cf6d272bfd0c 286 Gene3D G3DSA:3.40.50.720 2 219 1.1E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00820 3037c344565afe4a9958cf6d272bfd0c 286 SUPERFAMILY SSF51735 2 276 2.33E-53 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00820 3037c344565afe4a9958cf6d272bfd0c 286 PANTHER PTHR14194 2 282 1.5E-78 T 23-04-2016 DC74_RS01310 19a85272cc3c599bdc1aaeed70d118ac 158 PANTHER PTHR35344:SF3 16 130 5.7E-55 T 23-04-2016 DC74_RS01310 19a85272cc3c599bdc1aaeed70d118ac 158 Pfam PF00741 Gas vesicle protein 21 59 7.9E-12 T 23-04-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 DC74_RS01310 19a85272cc3c599bdc1aaeed70d118ac 158 PANTHER PTHR35344 16 130 5.7E-55 T 23-04-2016 DC74_RS01310 19a85272cc3c599bdc1aaeed70d118ac 158 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 10 98 26.874 T 23-04-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 DC74_RS01310 19a85272cc3c599bdc1aaeed70d118ac 158 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 22 36 - T 23-04-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 DC74_RS01310 19a85272cc3c599bdc1aaeed70d118ac 158 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 55 68 - T 23-04-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 Gene3D G3DSA:1.10.510.10 101 284 7.8E-39 T 23-04-2016 DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 SUPERFAMILY SSF56112 12 267 5.13E-64 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 SUPERFAMILY SSF56112 316 366 5.13E-64 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 PANTHER PTHR24362 8 267 3.5E-90 T 23-04-2016 DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 487 638 8.1E-28 T 23-04-2016 DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 SMART SM00220 15 262 1.1E-39 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 SUPERFAMILY SSF49899 440 642 6.02E-33 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 Pfam PF00069 Protein kinase domain 15 262 2.1E-37 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 Gene3D G3DSA:2.60.120.200 479 642 2.3E-29 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 PANTHER PTHR24362:SF247 8 267 3.5E-90 T 23-04-2016 DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 SMART SM00560 505 635 4.3E-33 T 23-04-2016 IPR006558 LamG-like jellyroll fold DC74_RS06030 5b540ab1b4818ffb70ae0062ade69564 646 Gene3D G3DSA:3.30.200.20 8 92 1.2E-13 T 23-04-2016 DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 SUPERFAMILY SSF52210 208 350 1.44E-31 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 Gene3D G3DSA:3.30.470.20 548 644 2.1E-6 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 Gene3D G3DSA:3.40.50.720 68 192 5.2E-21 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 SMART SM00881 72 167 2.2E-16 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 214 348 2.0E-43 T 23-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 SUPERFAMILY SSF56059 544 755 4.42E-41 T 23-04-2016 DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 PANTHER PTHR33303:SF3 69 493 2.2E-155 T 23-04-2016 DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 PANTHER PTHR33303:SF3 519 755 2.2E-155 T 23-04-2016 DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 SUPERFAMILY SSF52210 354 511 1.1E-25 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 SUPERFAMILY SSF51735 69 197 1.74E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 Pfam PF13549 ATP-grasp domain 536 752 9.2E-64 T 23-04-2016 DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 Pfam PF13380 CoA binding domain 77 197 4.4E-13 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 Gene3D G3DSA:3.40.50.261 193 346 1.6E-15 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 PANTHER PTHR33303 69 493 2.2E-155 T 23-04-2016 DC74_RS18335 2fc971545efc745ee549f3fc47754d66 757 PANTHER PTHR33303 519 755 2.2E-155 T 23-04-2016 DC74_RS03805 f219cee755df334e3c8211895f4fd7cd 225 PANTHER PTHR26402 1 223 5.8E-94 T 23-04-2016 DC74_RS03805 f219cee755df334e3c8211895f4fd7cd 225 PANTHER PTHR26402:SF316 1 223 5.8E-94 T 23-04-2016 DC74_RS03805 f219cee755df334e3c8211895f4fd7cd 225 SMART SM00862 145 220 1.4E-27 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS03805 f219cee755df334e3c8211895f4fd7cd 225 SUPERFAMILY SSF46894 119 221 5.95E-30 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS03805 f219cee755df334e3c8211895f4fd7cd 225 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS03805 f219cee755df334e3c8211895f4fd7cd 225 SUPERFAMILY SSF52172 1 129 1.02E-39 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS03805 f219cee755df334e3c8211895f4fd7cd 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 2.8E-25 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS03805 f219cee755df334e3c8211895f4fd7cd 225 Gene3D G3DSA:3.40.50.2300 1 120 9.0E-41 T 23-04-2016 DC74_RS03805 f219cee755df334e3c8211895f4fd7cd 225 SMART SM00448 1 112 3.3E-41 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS03805 f219cee755df334e3c8211895f4fd7cd 225 Gene3D G3DSA:1.10.10.10 124 221 5.8E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 PANTHER PTHR24423 191 477 9.3E-63 T 23-04-2016 DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 PANTHER PTHR24423 3 20 9.3E-63 T 23-04-2016 DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 SMART SM00388 257 324 9.1E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 476 2.6E-17 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 SMART SM00304 197 249 8.0E-15 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 324 6.8E-14 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 SUPERFAMILY SSF158472 197 247 4.97E-9 T 23-04-2016 DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 SUPERFAMILY SSF47384 243 324 1.2E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 SMART SM00387 365 477 1.5E-27 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 SUPERFAMILY SSF55874 313 477 2.1E-34 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 Pfam PF00672 HAMP domain 182 245 5.6E-14 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 Gene3D G3DSA:3.30.565.10 311 478 1.7E-38 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 2.0E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 431 2.0E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 474 2.0E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 417 2.0E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS34690 73fa8f076df4474f77e91ed3963775d3 483 Gene3D G3DSA:1.10.287.130 250 310 1.9E-14 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 PANTHER PTHR32282 1 998 0.0 T 23-04-2016 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Gene3D G3DSA:1.20.1580.10 92 130 9.2E-57 T 23-04-2016 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Gene3D G3DSA:1.20.1580.10 412 482 9.2E-57 T 23-04-2016 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Gene3D G3DSA:1.20.1580.10 255 288 9.2E-57 T 23-04-2016 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 SUPERFAMILY SSF52540 435 574 3.7E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 SUPERFAMILY SSF52540 10 205 3.7E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Gene3D G3DSA:1.20.1580.10 698 824 2.7E-55 T 23-04-2016 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Pfam PF00005 ABC transporter 628 864 1.4E-9 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Gene3D G3DSA:3.30.1490.20 201 240 2.3E-24 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Gene3D G3DSA:3.30.1490.20 131 154 2.3E-24 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 ProSitePatterns PS00211 ABC transporters family signature. 834 848 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 SUPERFAMILY SSF52540 619 913 1.5E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 944 22.715 T 23-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Gene3D G3DSA:1.10.8.280 290 411 2.5E-37 T 23-04-2016 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 PANTHER PTHR32282:SF2 1 998 0.0 T 23-04-2016 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 929 0.0 T 23-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Gene3D G3DSA:3.40.50.300 616 677 2.8E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Gene3D G3DSA:3.40.50.300 825 942 2.8E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Gene3D G3DSA:3.40.50.300 6 90 5.1E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11895 889f1f78f31bdb24f0ea5fce667d4778 1029 Gene3D G3DSA:3.40.50.300 483 600 5.1E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06020 b77ffbba1b31fbeeb7e56f454e03818f 144 SUPERFAMILY SSF50475 1 134 6.06E-31 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS06020 b77ffbba1b31fbeeb7e56f454e03818f 144 PANTHER PTHR35176 1 144 1.6E-17 T 23-04-2016 DC74_RS06020 b77ffbba1b31fbeeb7e56f454e03818f 144 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 12 129 1.9E-33 T 23-04-2016 IPR019920 F420-binding domain, putative DC74_RS06020 b77ffbba1b31fbeeb7e56f454e03818f 144 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 86 5.0E-17 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS06020 b77ffbba1b31fbeeb7e56f454e03818f 144 Gene3D G3DSA:2.30.110.10 7 130 2.7E-31 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS08345 0180cff0ef34463e98bbb9bbdc26ebf6 508 Gene3D G3DSA:1.25.40.10 240 450 4.3E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS10400 f91fcedfed53c0cc446f9a017d193df6 534 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 34 46 1.3E-20 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS10400 f91fcedfed53c0cc446f9a017d193df6 534 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 47 57 1.3E-20 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS10400 f91fcedfed53c0cc446f9a017d193df6 534 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 109 121 1.3E-20 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS10400 f91fcedfed53c0cc446f9a017d193df6 534 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 349 355 1.3E-20 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS10400 f91fcedfed53c0cc446f9a017d193df6 534 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 378 390 1.3E-20 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS10400 f91fcedfed53c0cc446f9a017d193df6 534 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 63 75 1.3E-20 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS10400 f91fcedfed53c0cc446f9a017d193df6 534 Gene3D G3DSA:3.50.50.60 32 275 3.6E-43 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS10400 f91fcedfed53c0cc446f9a017d193df6 534 SUPERFAMILY SSF51905 33 260 5.51E-35 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS10400 f91fcedfed53c0cc446f9a017d193df6 534 SUPERFAMILY SSF51905 434 460 5.51E-35 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS10400 f91fcedfed53c0cc446f9a017d193df6 534 Pfam PF01266 FAD dependent oxidoreductase 35 389 4.5E-46 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DC74_RS10400 f91fcedfed53c0cc446f9a017d193df6 534 PANTHER PTHR11985 9 512 8.8E-169 T 23-04-2016 DC74_RS10400 f91fcedfed53c0cc446f9a017d193df6 534 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 420 517 8.6E-14 T 23-04-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS07070 151425fa155d9515db79a55b3f2ab7a3 243 PANTHER PTHR38588 2 202 2.1E-24 T 23-04-2016 DC74_RS07070 151425fa155d9515db79a55b3f2ab7a3 243 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 7 141 6.8E-17 T 23-04-2016 IPR010419 Carbon monoxide dehydrogenase subunit G DC74_RS07070 151425fa155d9515db79a55b3f2ab7a3 243 SUPERFAMILY SSF55961 1 146 1.51E-30 T 23-04-2016 DC74_RS07070 151425fa155d9515db79a55b3f2ab7a3 243 PANTHER PTHR38588:SF1 2 202 2.1E-24 T 23-04-2016 DC74_RS07070 151425fa155d9515db79a55b3f2ab7a3 243 Gene3D G3DSA:3.30.530.20 1 145 8.5E-36 T 23-04-2016 IPR023393 START-like domain DC74_RS34090 cb0c4448b299f33b0b56341b71ebab75 358 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 58 339 3.6E-57 T 23-04-2016 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 DC74_RS34090 cb0c4448b299f33b0b56341b71ebab75 358 SUPERFAMILY SSF53850 56 276 2.18E-46 T 23-04-2016 DC74_RS34090 cb0c4448b299f33b0b56341b71ebab75 358 Pfam PF09084 NMT1/THI5 like 96 271 3.6E-15 T 23-04-2016 IPR015168 SsuA/THI5-like DC74_RS34090 cb0c4448b299f33b0b56341b71ebab75 358 PANTHER PTHR30024:SF3 56 342 2.1E-84 T 23-04-2016 DC74_RS34090 cb0c4448b299f33b0b56341b71ebab75 358 SMART SM00062 56 270 2.2E-11 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS34090 cb0c4448b299f33b0b56341b71ebab75 358 Gene3D G3DSA:3.40.190.10 134 231 3.4E-29 T 23-04-2016 DC74_RS34090 cb0c4448b299f33b0b56341b71ebab75 358 PANTHER PTHR30024 56 342 2.1E-84 T 23-04-2016 DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 Pfam PF01493 GXGXG motif 1280 1455 1.2E-76 T 23-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 Gene3D G3DSA:3.20.20.70 463 819 5.1E-104 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 Pfam PF01645 Conserved region in glutamate synthase 833 1195 4.0E-156 T 23-04-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 Pfam PF00310 Glutamine amidotransferases class-II 40 452 4.9E-180 T 23-04-2016 IPR017932 Glutamine amidotransferase type 2 domain DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 SUPERFAMILY SSF56235 40 454 6.86E-146 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 Gene3D G3DSA:3.20.20.70 845 1228 8.0E-180 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 SUPERFAMILY SSF51395 467 1232 2.24E-263 T 23-04-2016 DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 Gene3D G3DSA:3.60.20.10 40 462 7.1E-185 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 Pfam PF04898 Glutamate synthase central domain 479 767 2.6E-112 T 23-04-2016 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 UniPathway: UPA00045 DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 PANTHER PTHR11938:SF1 29 1514 0.0 T 23-04-2016 DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 Gene3D G3DSA:2.160.20.60 1250 1524 1.1E-104 T 23-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 PANTHER PTHR11938 29 1514 0.0 T 23-04-2016 DC74_RS12270 9796721b083bb0141d52e426b8f6e979 1536 SUPERFAMILY SSF69336 1244 1509 9.02E-89 T 23-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 DC74_RS09305 095208e8636f9366993baf3b5b24425f 496 PANTHER PTHR23501:SF48 14 474 1.7E-97 T 23-04-2016 DC74_RS09305 095208e8636f9366993baf3b5b24425f 496 PANTHER PTHR23501 14 474 1.7E-97 T 23-04-2016 DC74_RS09305 095208e8636f9366993baf3b5b24425f 496 Gene3D G3DSA:1.20.1250.20 265 473 2.8E-13 T 23-04-2016 DC74_RS09305 095208e8636f9366993baf3b5b24425f 496 SUPERFAMILY SSF103473 256 464 2.75E-55 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS09305 095208e8636f9366993baf3b5b24425f 496 SUPERFAMILY SSF103473 8 206 2.75E-55 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS09305 095208e8636f9366993baf3b5b24425f 496 Gene3D G3DSA:1.20.1250.20 22 203 1.8E-23 T 23-04-2016 DC74_RS09305 095208e8636f9366993baf3b5b24425f 496 Pfam PF07690 Major Facilitator Superfamily 36 417 1.4E-37 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS36275 dd884dc75f7848f9e63dbd66257dec45 591 SUPERFAMILY SSF55486 240 583 3.66E-68 T 23-04-2016 DC74_RS36275 dd884dc75f7848f9e63dbd66257dec45 591 Pfam PF03413 Peptidase propeptide and YPEB domain 129 195 8.8E-5 T 23-04-2016 IPR025711 PepSY domain DC74_RS36275 dd884dc75f7848f9e63dbd66257dec45 591 Gene3D G3DSA:1.10.390.10 415 583 2.4E-45 T 23-04-2016 DC74_RS36275 dd884dc75f7848f9e63dbd66257dec45 591 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 67 114 1.9E-11 T 23-04-2016 IPR011096 FTP domain DC74_RS36275 dd884dc75f7848f9e63dbd66257dec45 591 PANTHER PTHR33794 44 585 2.1E-110 T 23-04-2016 DC74_RS36275 dd884dc75f7848f9e63dbd66257dec45 591 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 485 501 5.1E-9 T 23-04-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 DC74_RS36275 dd884dc75f7848f9e63dbd66257dec45 591 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 350 370 5.1E-9 T 23-04-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 DC74_RS36275 dd884dc75f7848f9e63dbd66257dec45 591 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 388 404 5.1E-9 T 23-04-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 DC74_RS36275 dd884dc75f7848f9e63dbd66257dec45 591 Gene3D G3DSA:3.10.170.10 244 401 3.5E-39 T 23-04-2016 IPR013856 Peptidase M4 domain GO:0004222 DC74_RS36275 dd884dc75f7848f9e63dbd66257dec45 591 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 415 583 1.7E-44 T 23-04-2016 IPR001570 Peptidase M4, C-terminal GO:0004222 DC74_RS36275 dd884dc75f7848f9e63dbd66257dec45 591 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 244 396 1.3E-40 T 23-04-2016 IPR013856 Peptidase M4 domain GO:0004222 DC74_RS31500 560885501a3a9a6b1faf0809e58d9473 337 PANTHER PTHR30036:SF2 4 337 1.0E-111 T 23-04-2016 DC74_RS31500 560885501a3a9a6b1faf0809e58d9473 337 SUPERFAMILY SSF53822 54 324 8.01E-51 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS31500 560885501a3a9a6b1faf0809e58d9473 337 Pfam PF13407 Periplasmic binding protein domain 56 300 8.8E-40 T 23-04-2016 IPR025997 Periplasmic binding protein DC74_RS31500 560885501a3a9a6b1faf0809e58d9473 337 Gene3D G3DSA:3.40.50.2300 50 171 2.4E-31 T 23-04-2016 DC74_RS31500 560885501a3a9a6b1faf0809e58d9473 337 Gene3D G3DSA:3.40.50.2300 172 306 8.4E-19 T 23-04-2016 DC74_RS31500 560885501a3a9a6b1faf0809e58d9473 337 PANTHER PTHR30036 4 337 1.0E-111 T 23-04-2016 DC74_RS16720 9aacf26b4cd58a951a5d8a02621f519c 446 Gene3D G3DSA:3.40.190.10 56 177 1.1E-18 T 23-04-2016 DC74_RS16720 9aacf26b4cd58a951a5d8a02621f519c 446 SUPERFAMILY SSF53850 48 437 1.14E-51 T 23-04-2016 DC74_RS16720 9aacf26b4cd58a951a5d8a02621f519c 446 Pfam PF01547 Bacterial extracellular solute-binding protein 62 355 5.5E-28 T 23-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 DC74_RS16720 9aacf26b4cd58a951a5d8a02621f519c 446 PANTHER PTHR30061 2 440 3.9E-144 T 23-04-2016 DC74_RS16720 9aacf26b4cd58a951a5d8a02621f519c 446 Gene3D G3DSA:3.40.190.10 178 371 7.1E-28 T 23-04-2016 DC74_RS16720 9aacf26b4cd58a951a5d8a02621f519c 446 PANTHER PTHR30061:SF2 2 440 3.9E-144 T 23-04-2016 DC74_RS11295 541aef88cb90b0f5b030285c5a91db6c 172 SUPERFAMILY SSF53254 6 155 4.93E-27 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS11295 541aef88cb90b0f5b030285c5a91db6c 172 SMART SM00855 8 119 8.7E-6 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS11295 541aef88cb90b0f5b030285c5a91db6c 172 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 135 1.6E-11 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS11295 541aef88cb90b0f5b030285c5a91db6c 172 Gene3D G3DSA:3.40.50.1240 4 171 1.5E-57 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS11295 541aef88cb90b0f5b030285c5a91db6c 172 PANTHER PTHR20935 7 108 5.8E-23 T 23-04-2016 DC74_RS07915 2694d61abeba35eb7b75124b8c1c4b8c 200 PANTHER PTHR30328:SF4 1 193 4.8E-27 T 23-04-2016 DC74_RS07915 2694d61abeba35eb7b75124b8c1c4b8c 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 7.0E-16 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS07915 2694d61abeba35eb7b75124b8c1c4b8c 200 SUPERFAMILY SSF48498 87 189 3.16E-11 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS07915 2694d61abeba35eb7b75124b8c1c4b8c 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 5.2E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS07915 2694d61abeba35eb7b75124b8c1c4b8c 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 5.2E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS07915 2694d61abeba35eb7b75124b8c1c4b8c 200 SUPERFAMILY SSF46689 7 72 9.98E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07915 2694d61abeba35eb7b75124b8c1c4b8c 200 Gene3D G3DSA:1.10.357.10 15 198 1.0E-27 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS07915 2694d61abeba35eb7b75124b8c1c4b8c 200 PANTHER PTHR30328 1 193 4.8E-27 T 23-04-2016 DC74_RS13555 3c89c52491a6918b1faba4ed3ab4cc3f 342 Gene3D G3DSA:3.40.50.1980 186 341 1.4E-33 T 23-04-2016 DC74_RS13555 3c89c52491a6918b1faba4ed3ab4cc3f 342 SUPERFAMILY SSF53807 70 336 5.1E-62 T 23-04-2016 DC74_RS13555 3c89c52491a6918b1faba4ed3ab4cc3f 342 Pfam PF01497 Periplasmic binding protein 91 312 1.8E-26 T 23-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 DC74_RS13555 3c89c52491a6918b1faba4ed3ab4cc3f 342 Gene3D G3DSA:3.40.50.1980 68 185 9.6E-37 T 23-04-2016 DC74_RS13555 3c89c52491a6918b1faba4ed3ab4cc3f 342 PANTHER PTHR30532 3 34 1.1E-69 T 23-04-2016 DC74_RS13555 3c89c52491a6918b1faba4ed3ab4cc3f 342 PANTHER PTHR30532 61 342 1.1E-69 T 23-04-2016 DC74_RS19570 b74b8746fd3b2bf2b1156f8c6dfa7a04 263 Gene3D G3DSA:3.40.50.150 93 229 6.9E-12 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS19570 b74b8746fd3b2bf2b1156f8c6dfa7a04 263 PANTHER PTHR23417 43 262 1.3E-62 T 23-04-2016 DC74_RS19570 b74b8746fd3b2bf2b1156f8c6dfa7a04 263 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 50 262 28.855 T 23-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 DC74_RS19570 b74b8746fd3b2bf2b1156f8c6dfa7a04 263 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 91 261 3.0E-44 T 23-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 DC74_RS19570 b74b8746fd3b2bf2b1156f8c6dfa7a04 263 PANTHER PTHR23417:SF14 43 262 1.3E-62 T 23-04-2016 DC74_RS19570 b74b8746fd3b2bf2b1156f8c6dfa7a04 263 Pfam PF02390 Putative methyltransferase 91 256 9.4E-49 T 23-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 DC74_RS19570 b74b8746fd3b2bf2b1156f8c6dfa7a04 263 SUPERFAMILY SSF53335 41 262 2.56E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS16545 fe8105fee4b8c02d2f816b09f4d19dcf 287 Pfam PF00561 alpha/beta hydrolase fold 25 263 6.2E-22 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS16545 fe8105fee4b8c02d2f816b09f4d19dcf 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 1.6E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS16545 fe8105fee4b8c02d2f816b09f4d19dcf 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 1.6E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS16545 fe8105fee4b8c02d2f816b09f4d19dcf 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 1.6E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS16545 fe8105fee4b8c02d2f816b09f4d19dcf 287 Gene3D G3DSA:3.40.50.1820 3 285 8.0E-57 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS16545 fe8105fee4b8c02d2f816b09f4d19dcf 287 SUPERFAMILY SSF53474 2 285 2.16E-50 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS16545 fe8105fee4b8c02d2f816b09f4d19dcf 287 PANTHER PTHR10992 1 162 3.9E-41 T 23-04-2016 DC74_RS16545 fe8105fee4b8c02d2f816b09f4d19dcf 287 PANTHER PTHR10992 209 286 3.9E-41 T 23-04-2016 DC74_RS27970 3433e72cc873ab4af61d936d489d10f4 61 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 56 3.0E-22 T 23-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS27970 3433e72cc873ab4af61d936d489d10f4 61 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 61 15.768 T 23-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS27970 3433e72cc873ab4af61d936d489d10f4 61 SUPERFAMILY SSF143800 2 59 3.92E-22 T 23-04-2016 DC74_RS27970 3433e72cc873ab4af61d936d489d10f4 61 Pfam PF00830 Ribosomal L28 family 4 58 3.8E-22 T 23-04-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 DC74_RS27970 3433e72cc873ab4af61d936d489d10f4 61 Gene3D G3DSA:4.10.1160.10 19 61 2.0E-22 T 23-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS39070 3acb556e7ec1ce98d9e6a02e27cce123 435 SMART SM00729 196 403 1.3E-12 T 23-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 DC74_RS39070 3acb556e7ec1ce98d9e6a02e27cce123 435 Pfam PF04055 Radical SAM superfamily 203 343 1.6E-8 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS39070 3acb556e7ec1ce98d9e6a02e27cce123 435 PANTHER PTHR11918:SF64 21 381 2.0E-30 T 23-04-2016 DC74_RS39070 3acb556e7ec1ce98d9e6a02e27cce123 435 SUPERFAMILY SSF102114 165 383 3.79E-21 T 23-04-2016 DC74_RS39070 3acb556e7ec1ce98d9e6a02e27cce123 435 Gene3D G3DSA:3.80.30.20 199 405 7.5E-23 T 23-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe DC74_RS39070 3acb556e7ec1ce98d9e6a02e27cce123 435 PANTHER PTHR11918 21 381 2.0E-30 T 23-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 Pfam PF00989 PAS fold 170 269 1.3E-7 T 23-04-2016 IPR013767 PAS fold GO:0006355 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 SUPERFAMILY SSF81606 672 880 2.88E-6 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 690 880 5.8E-42 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 SMART SM00065 488 642 0.024 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 SMART SM00065 309 453 4.9E-12 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 SUPERFAMILY SSF55785 170 264 6.11E-16 T 23-04-2016 IPR000014 PAS domain DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 Gene3D G3DSA:3.30.450.40 463 640 7.7E-22 T 23-04-2016 IPR029016 GAF domain-like DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 PANTHER PTHR21021 638 886 3.5E-66 T 23-04-2016 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 PANTHER PTHR21021 397 458 3.5E-66 T 23-04-2016 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 SUPERFAMILY SSF55781 459 640 5.56E-11 T 23-04-2016 IPR029016 GAF domain-like DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 Pfam PF13492 GAF domain 585 634 8.9E-7 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 Pfam PF13185 GAF domain 309 444 3.6E-10 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 SUPERFAMILY SSF55781 310 448 3.27E-19 T 23-04-2016 IPR029016 GAF domain-like DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 SMART SM00331 663 880 8.0E-66 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 PANTHER PTHR21021:SF19 638 886 3.5E-66 T 23-04-2016 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 PANTHER PTHR21021:SF19 397 458 3.5E-66 T 23-04-2016 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 Gene3D G3DSA:3.30.450.20 170 269 2.4E-12 T 23-04-2016 DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 170 269 1.5E-9 T 23-04-2016 IPR000014 PAS domain DC74_RS28645 f92fab4c3e738b684859734e235ab3c4 886 Gene3D G3DSA:3.30.450.40 308 450 1.3E-19 T 23-04-2016 IPR029016 GAF domain-like DC74_RS36430 6de2972df6533ec868f78cddafaa9842 287 Gene3D G3DSA:3.40.50.1820 7 286 4.6E-67 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS36430 6de2972df6533ec868f78cddafaa9842 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 2.2E-18 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36430 6de2972df6533ec868f78cddafaa9842 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 2.2E-18 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36430 6de2972df6533ec868f78cddafaa9842 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 231 245 2.2E-18 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36430 6de2972df6533ec868f78cddafaa9842 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 62 77 2.2E-18 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36430 6de2972df6533ec868f78cddafaa9842 287 Pfam PF00561 alpha/beta hydrolase fold 34 273 1.4E-27 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36430 6de2972df6533ec868f78cddafaa9842 287 SUPERFAMILY SSF53474 8 286 8.17E-64 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS36430 6de2972df6533ec868f78cddafaa9842 287 PANTHER PTHR10992 12 287 2.2E-53 T 23-04-2016 DC74_RS22475 7ba2509254456bb6c0b57fae769527da 214 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 49 180 2.1E-45 T 23-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 DC74_RS22475 7ba2509254456bb6c0b57fae769527da 214 SUPERFAMILY SSF55083 48 191 4.71E-51 T 23-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 DC74_RS22475 7ba2509254456bb6c0b57fae769527da 214 Gene3D G3DSA:3.30.70.560 48 201 1.6E-57 T 23-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 DC74_RS22475 7ba2509254456bb6c0b57fae769527da 214 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 50 180 1.8E-38 T 23-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 DC74_RS22475 7ba2509254456bb6c0b57fae769527da 214 PANTHER PTHR20941:SF10 23 203 2.6E-81 T 23-04-2016 DC74_RS22475 7ba2509254456bb6c0b57fae769527da 214 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 135 146 - T 23-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 DC74_RS22475 7ba2509254456bb6c0b57fae769527da 214 PANTHER PTHR20941 23 203 2.6E-81 T 23-04-2016 DC74_RS08220 30ac89268b17642ddfda77faf87279de 202 SUPERFAMILY SSF52540 17 192 1.44E-22 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS08220 30ac89268b17642ddfda77faf87279de 202 PANTHER PTHR11711 18 198 6.9E-62 T 23-04-2016 DC74_RS08220 30ac89268b17642ddfda77faf87279de 202 Gene3D G3DSA:3.40.50.300 16 196 8.8E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS08220 30ac89268b17642ddfda77faf87279de 202 Pfam PF03029 Conserved hypothetical ATP binding protein 23 190 9.9E-28 T 23-04-2016 IPR004130 GPN-loop GTPase DC74_RS08220 30ac89268b17642ddfda77faf87279de 202 PANTHER PTHR11711:SF117 18 198 6.9E-62 T 23-04-2016 DC74_RS06740 130adb4dcdb3eabe577d0e2541dd213b 616 Pfam PF00005 ABC transporter 383 536 1.5E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS06740 130adb4dcdb3eabe577d0e2541dd213b 616 Gene3D G3DSA:1.20.1560.10 36 338 5.0E-16 T 23-04-2016 DC74_RS06740 130adb4dcdb3eabe577d0e2541dd213b 616 SMART SM00382 392 582 6.9E-19 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS06740 130adb4dcdb3eabe577d0e2541dd213b 616 Gene3D G3DSA:3.40.50.300 366 599 1.3E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06740 130adb4dcdb3eabe577d0e2541dd213b 616 PANTHER PTHR24221 20 193 1.5E-87 T 23-04-2016 DC74_RS06740 130adb4dcdb3eabe577d0e2541dd213b 616 PANTHER PTHR24221 223 615 1.5E-87 T 23-04-2016 DC74_RS06740 130adb4dcdb3eabe577d0e2541dd213b 616 SUPERFAMILY SSF90123 31 334 1.57E-20 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS06740 130adb4dcdb3eabe577d0e2541dd213b 616 SUPERFAMILY SSF52540 359 606 1.44E-69 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36520 ef4521fdff48696c1f32889d72a42737 399 ProSitePatterns PS00216 Sugar transport proteins signature 1. 75 91 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS36520 ef4521fdff48696c1f32889d72a42737 399 PANTHER PTHR23517:SF3 1 383 2.9E-67 T 23-04-2016 DC74_RS36520 ef4521fdff48696c1f32889d72a42737 399 Gene3D G3DSA:1.20.1250.20 24 203 4.4E-33 T 23-04-2016 DC74_RS36520 ef4521fdff48696c1f32889d72a42737 399 Gene3D G3DSA:1.20.1250.20 214 397 5.2E-23 T 23-04-2016 DC74_RS36520 ef4521fdff48696c1f32889d72a42737 399 Pfam PF07690 Major Facilitator Superfamily 36 306 1.3E-35 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS36520 ef4521fdff48696c1f32889d72a42737 399 PANTHER PTHR23517 1 383 2.9E-67 T 23-04-2016 DC74_RS36520 ef4521fdff48696c1f32889d72a42737 399 SUPERFAMILY SSF103473 22 396 4.19E-58 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS10810 d7159bb39cdf270543d7e97dcd5ebf0a 155 SUPERFAMILY SSF54909 64 146 1.74E-14 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS10810 d7159bb39cdf270543d7e97dcd5ebf0a 155 Gene3D G3DSA:3.30.70.920 54 145 1.5E-18 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS10810 d7159bb39cdf270543d7e97dcd5ebf0a 155 SUPERFAMILY SSF46785 1 59 4.01E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10810 d7159bb39cdf270543d7e97dcd5ebf0a 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.6E-15 T 23-04-2016 DC74_RS10810 d7159bb39cdf270543d7e97dcd5ebf0a 155 PANTHER PTHR30154 1 150 9.4E-44 T 23-04-2016 DC74_RS10810 d7159bb39cdf270543d7e97dcd5ebf0a 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 5.6E-13 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS10810 d7159bb39cdf270543d7e97dcd5ebf0a 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 5.6E-13 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS10810 d7159bb39cdf270543d7e97dcd5ebf0a 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 5.6E-13 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS10810 d7159bb39cdf270543d7e97dcd5ebf0a 155 PANTHER PTHR30154:SF28 1 150 9.4E-44 T 23-04-2016 DC74_RS10810 d7159bb39cdf270543d7e97dcd5ebf0a 155 Gene3D G3DSA:1.10.10.10 1 52 7.9E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10810 d7159bb39cdf270543d7e97dcd5ebf0a 155 SMART SM00344 1 110 8.3E-38 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS10810 d7159bb39cdf270543d7e97dcd5ebf0a 155 Pfam PF01037 Lrp/AsnC ligand binding domain 69 139 4.0E-15 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS26640 789f42efc6a7baeda22bbbee5f06d271 409 SUPERFAMILY SSF53223 32 180 9.35E-56 T 23-04-2016 DC74_RS26640 789f42efc6a7baeda22bbbee5f06d271 409 PANTHER PTHR23406:SF33 40 409 5.1E-253 T 23-04-2016 DC74_RS26640 789f42efc6a7baeda22bbbee5f06d271 409 PANTHER PTHR23406 40 409 5.1E-253 T 23-04-2016 DC74_RS26640 789f42efc6a7baeda22bbbee5f06d271 409 SMART SM01274 37 170 1.5E-77 T 23-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DC74_RS26640 789f42efc6a7baeda22bbbee5f06d271 409 PIRSF PIRSF000106 37 409 2.3E-74 T 23-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 DC74_RS26640 789f42efc6a7baeda22bbbee5f06d271 409 SUPERFAMILY SSF51735 182 408 3.85E-68 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26640 789f42efc6a7baeda22bbbee5f06d271 409 Pfam PF00390 Malic enzyme, N-terminal domain 39 170 2.5E-27 T 23-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DC74_RS26640 789f42efc6a7baeda22bbbee5f06d271 409 Pfam PF03949 Malic enzyme, NAD binding domain 184 383 3.4E-20 T 23-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 DC74_RS26640 789f42efc6a7baeda22bbbee5f06d271 409 SMART SM00919 182 402 1.3E-108 T 23-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 DC74_RS26640 789f42efc6a7baeda22bbbee5f06d271 409 Gene3D G3DSA:3.40.50.720 180 408 2.1E-70 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26640 789f42efc6a7baeda22bbbee5f06d271 409 Gene3D G3DSA:3.40.50.10380 35 179 6.8E-54 T 23-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DC74_RS14020 848dd03bf9e6259317f40f3e990bf337 232 SUPERFAMILY SSF51182 22 225 5.35E-48 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS14020 848dd03bf9e6259317f40f3e990bf337 232 PANTHER PTHR13903 10 225 4.8E-67 T 23-04-2016 IPR012093 Pirin DC74_RS14020 848dd03bf9e6259317f40f3e990bf337 232 Gene3D G3DSA:2.60.120.10 21 225 3.7E-45 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS14020 848dd03bf9e6259317f40f3e990bf337 232 Pfam PF02678 Pirin 26 129 3.1E-29 T 23-04-2016 IPR003829 Pirin, N-terminal domain DC74_RS14020 848dd03bf9e6259317f40f3e990bf337 232 PANTHER PTHR13903:SF7 10 225 4.8E-67 T 23-04-2016 DC74_RS33570 186b8a6d50fe22f291f5a2b88318dd59 337 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS33570 186b8a6d50fe22f291f5a2b88318dd59 337 Pfam PF00107 Zinc-binding dehydrogenase 172 281 2.8E-15 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS33570 186b8a6d50fe22f291f5a2b88318dd59 337 SUPERFAMILY SSF50129 1 139 2.13E-55 T 23-04-2016 IPR011032 GroES-like DC74_RS33570 186b8a6d50fe22f291f5a2b88318dd59 337 SUPERFAMILY SSF50129 303 329 2.13E-55 T 23-04-2016 IPR011032 GroES-like DC74_RS33570 186b8a6d50fe22f291f5a2b88318dd59 337 SUPERFAMILY SSF51735 139 298 3.04E-25 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS33570 186b8a6d50fe22f291f5a2b88318dd59 337 Gene3D G3DSA:3.90.180.10 1 165 2.5E-56 T 23-04-2016 IPR011032 GroES-like DC74_RS33570 186b8a6d50fe22f291f5a2b88318dd59 337 PANTHER PTHR11695 12 333 3.6E-104 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS33570 186b8a6d50fe22f291f5a2b88318dd59 337 Gene3D G3DSA:3.40.50.720 166 279 2.0E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS33570 186b8a6d50fe22f291f5a2b88318dd59 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 130 1.2E-32 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS33570 186b8a6d50fe22f291f5a2b88318dd59 337 PANTHER PTHR11695:SF429 12 333 3.6E-104 T 23-04-2016 DC74_RS01895 9651534307169788ecfdfb39e0e15292 286 SUPERFAMILY SSF53901 22 152 4.19E-15 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS01895 9651534307169788ecfdfb39e0e15292 286 SUPERFAMILY SSF53901 135 266 3.02E-7 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS01895 9651534307169788ecfdfb39e0e15292 286 Gene3D G3DSA:3.40.47.10 146 267 9.1E-5 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS01895 9651534307169788ecfdfb39e0e15292 286 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 90 151 6.0E-5 T 23-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS01895 9651534307169788ecfdfb39e0e15292 286 Gene3D G3DSA:3.40.47.10 26 145 1.2E-12 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 SUPERFAMILY SSF51984 11 121 1.2E-14 T 23-04-2016 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 PANTHER PTHR23135:SF2 66 499 9.0E-144 T 23-04-2016 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 SUPERFAMILY SSF53244 355 498 2.15E-39 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 Gene3D G3DSA:3.40.50.720 11 120 1.3E-17 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 Gene3D G3DSA:3.90.190.20 355 495 1.2E-45 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 PANTHER PTHR23135 66 499 9.0E-144 T 23-04-2016 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 138 161 - T 23-04-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 SUPERFAMILY SSF53623 135 351 6.54E-47 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 PANTHER PTHR23135 7 45 9.0E-144 T 23-04-2016 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 16 495 3.7E-111 T 23-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 Gene3D G3DSA:3.40.1190.10 121 352 7.3E-67 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 Pfam PF02875 Mur ligase family, glutamate ligase domain 355 423 1.2E-7 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 15 498 33.818 T 23-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 Pfam PF08245 Mur ligase middle domain 140 334 4.4E-25 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS12550 cb179fa5f3a50e6433078dcffe4e47df 503 PANTHER PTHR23135:SF2 7 45 9.0E-144 T 23-04-2016 DC74_RS18655 9c48d834346627e3451b7a7350f7bd68 200 SUPERFAMILY SSF54768 32 98 4.39E-22 T 23-04-2016 DC74_RS18655 9c48d834346627e3451b7a7350f7bd68 200 ProSitePatterns PS00585 Ribosomal protein S5 signature. 50 82 - T 23-04-2016 IPR018192 Ribosomal protein S5, N-terminal, conserved site DC74_RS18655 9c48d834346627e3451b7a7350f7bd68 200 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 31 185 6.0E-68 T 23-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 DC74_RS18655 9c48d834346627e3451b7a7350f7bd68 200 PANTHER PTHR13718 35 186 9.7E-71 T 23-04-2016 IPR000851 Ribosomal protein S5 GO:0003735|GO:0005840|GO:0006412 DC74_RS18655 9c48d834346627e3451b7a7350f7bd68 200 Gene3D G3DSA:3.30.160.20 33 94 8.0E-29 T 23-04-2016 IPR014720 Double-stranded RNA-binding domain DC74_RS18655 9c48d834346627e3451b7a7350f7bd68 200 Gene3D G3DSA:3.30.230.10 100 180 2.4E-32 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS18655 9c48d834346627e3451b7a7350f7bd68 200 Pfam PF03719 Ribosomal protein S5, C-terminal domain 109 179 1.5E-29 T 23-04-2016 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 DC74_RS18655 9c48d834346627e3451b7a7350f7bd68 200 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 185 34.823 T 23-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 DC74_RS18655 9c48d834346627e3451b7a7350f7bd68 200 Pfam PF00333 Ribosomal protein S5, N-terminal domain 35 97 1.3E-27 T 23-04-2016 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 DC74_RS18655 9c48d834346627e3451b7a7350f7bd68 200 SUPERFAMILY SSF54211 101 180 4.05E-25 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS15980 50da4d9b00c31f5edd74df121f8cb12c 230 SMART SM00862 151 226 1.7E-24 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS15980 50da4d9b00c31f5edd74df121f8cb12c 230 SMART SM00448 2 112 8.7E-34 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS15980 50da4d9b00c31f5edd74df121f8cb12c 230 PANTHER PTHR26402 2 229 1.8E-93 T 23-04-2016 DC74_RS15980 50da4d9b00c31f5edd74df121f8cb12c 230 PANTHER PTHR26402:SF578 2 229 1.8E-93 T 23-04-2016 DC74_RS15980 50da4d9b00c31f5edd74df121f8cb12c 230 Gene3D G3DSA:3.40.50.2300 1 123 2.3E-35 T 23-04-2016 DC74_RS15980 50da4d9b00c31f5edd74df121f8cb12c 230 Pfam PF00072 Response regulator receiver domain 4 111 4.1E-24 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS15980 50da4d9b00c31f5edd74df121f8cb12c 230 Gene3D G3DSA:1.10.10.10 129 229 5.1E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS15980 50da4d9b00c31f5edd74df121f8cb12c 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 224 4.5E-23 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS15980 50da4d9b00c31f5edd74df121f8cb12c 230 SUPERFAMILY SSF52172 1 184 1.99E-37 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS17110 21934ac2cfc92435ac8903c7d3be4629 194 Gene3D G3DSA:1.10.10.10 37 100 2.0E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19480 0632d554199ce82f3ff075d818e50780 349 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 237 1.5E-20 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS19480 0632d554199ce82f3ff075d818e50780 349 Gene3D G3DSA:3.40.50.720 4 187 4.8E-29 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19480 0632d554199ce82f3ff075d818e50780 349 SUPERFAMILY SSF51735 3 318 3.97E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19480 0632d554199ce82f3ff075d818e50780 349 PANTHER PTHR10366 4 257 3.8E-123 T 23-04-2016 DC74_RS19480 0632d554199ce82f3ff075d818e50780 349 PANTHER PTHR10366 276 343 3.8E-123 T 23-04-2016 DC74_RS19480 0632d554199ce82f3ff075d818e50780 349 PANTHER PTHR10366:SF5 4 257 3.8E-123 T 23-04-2016 DC74_RS19480 0632d554199ce82f3ff075d818e50780 349 PANTHER PTHR10366:SF5 276 343 3.8E-123 T 23-04-2016 DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 2.7E-15 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 Pfam PF00455 DeoR C terminal sensor domain 75 240 2.0E-50 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 SUPERFAMILY SSF46785 4 66 9.87E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 PANTHER PTHR30363:SF13 1 266 4.7E-78 T 23-04-2016 DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 SMART SM01134 72 242 4.8E-65 T 23-04-2016 DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 Gene3D G3DSA:3.40.50.1360 76 224 1.2E-20 T 23-04-2016 DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.3E-6 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.3E-6 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 PANTHER PTHR30363 1 266 4.7E-78 T 23-04-2016 DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 SMART SM00420 6 58 2.9E-13 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 SUPERFAMILY SSF100950 76 243 2.33E-32 T 23-04-2016 DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 23-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 DC74_RS32960 7269d6a5c1c8b35148df7cc4099efb3b 267 Gene3D G3DSA:1.10.10.10 1 59 1.6E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13985 4be77d3cc67121bb9596835cce3f5126 473 SUPERFAMILY SSF55874 337 455 1.23E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS13985 4be77d3cc67121bb9596835cce3f5126 473 Pfam PF07730 Histidine kinase 245 310 2.8E-19 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS13985 4be77d3cc67121bb9596835cce3f5126 473 Gene3D G3DSA:3.30.565.10 415 458 3.8E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS13985 4be77d3cc67121bb9596835cce3f5126 473 PANTHER PTHR24421:SF26 134 470 6.8E-91 T 23-04-2016 DC74_RS13985 4be77d3cc67121bb9596835cce3f5126 473 PANTHER PTHR24421 134 470 6.8E-91 T 23-04-2016 DC74_RS26180 7aa8fed4ebd78d86bf39cbf43ddcab5f 466 Pfam PF07687 Peptidase dimerisation domain 201 360 7.6E-21 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS26180 7aa8fed4ebd78d86bf39cbf43ddcab5f 466 Gene3D G3DSA:3.40.630.10 374 460 3.9E-63 T 23-04-2016 DC74_RS26180 7aa8fed4ebd78d86bf39cbf43ddcab5f 466 Gene3D G3DSA:3.40.630.10 8 198 3.9E-63 T 23-04-2016 DC74_RS26180 7aa8fed4ebd78d86bf39cbf43ddcab5f 466 Pfam PF01546 Peptidase family M20/M25/M40 88 455 8.8E-34 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS26180 7aa8fed4ebd78d86bf39cbf43ddcab5f 466 PANTHER PTHR11014:SF72 1 273 1.1E-202 T 23-04-2016 DC74_RS26180 7aa8fed4ebd78d86bf39cbf43ddcab5f 466 PANTHER PTHR11014:SF72 291 464 1.1E-202 T 23-04-2016 DC74_RS26180 7aa8fed4ebd78d86bf39cbf43ddcab5f 466 PANTHER PTHR11014 1 273 1.1E-202 T 23-04-2016 DC74_RS26180 7aa8fed4ebd78d86bf39cbf43ddcab5f 466 PANTHER PTHR11014 291 464 1.1E-202 T 23-04-2016 DC74_RS26180 7aa8fed4ebd78d86bf39cbf43ddcab5f 466 SUPERFAMILY SSF53187 375 460 2.74E-62 T 23-04-2016 DC74_RS26180 7aa8fed4ebd78d86bf39cbf43ddcab5f 466 SUPERFAMILY SSF53187 8 204 2.74E-62 T 23-04-2016 DC74_RS26180 7aa8fed4ebd78d86bf39cbf43ddcab5f 466 Gene3D G3DSA:3.30.70.360 204 367 2.3E-54 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS27490 1b6ab7064d9ad6bcc8050a46ff572da9 332 PANTHER PTHR30465 25 332 1.1E-120 T 23-04-2016 DC74_RS27490 1b6ab7064d9ad6bcc8050a46ff572da9 332 Gene3D G3DSA:1.10.3720.10 114 329 2.0E-29 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS27490 1b6ab7064d9ad6bcc8050a46ff572da9 332 SUPERFAMILY SSF161098 116 316 1.18E-27 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS27490 1b6ab7064d9ad6bcc8050a46ff572da9 332 PANTHER PTHR30465:SF69 25 332 1.1E-120 T 23-04-2016 DC74_RS27490 1b6ab7064d9ad6bcc8050a46ff572da9 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 139 331 1.9E-26 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS27490 1b6ab7064d9ad6bcc8050a46ff572da9 332 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 82 6.8E-10 T 23-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain DC74_RS21305 efabca94f16573bee62593b2026ea611 298 Gene3D G3DSA:3.20.20.190 10 295 7.2E-76 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS21305 efabca94f16573bee62593b2026ea611 298 SUPERFAMILY SSF51695 17 293 5.23E-65 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS21305 efabca94f16573bee62593b2026ea611 298 PANTHER PTHR23344 122 292 6.4E-65 T 23-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 DC74_RS21305 efabca94f16573bee62593b2026ea611 298 PANTHER PTHR23344 3 103 6.4E-65 T 23-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 DC74_RS21305 efabca94f16573bee62593b2026ea611 298 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 22 289 6.0E-44 T 23-04-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 DC74_RS27515 cb543294685fd4ff111ab2e1ea14530d 469 PANTHER PTHR11533:SF185 4 10 1.2E-87 T 23-04-2016 DC74_RS27515 cb543294685fd4ff111ab2e1ea14530d 469 PANTHER PTHR11533:SF185 30 466 1.2E-87 T 23-04-2016 DC74_RS27515 cb543294685fd4ff111ab2e1ea14530d 469 PANTHER PTHR11533 4 10 1.2E-87 T 23-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 DC74_RS27515 cb543294685fd4ff111ab2e1ea14530d 469 PANTHER PTHR11533 30 466 1.2E-87 T 23-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 DC74_RS27515 cb543294685fd4ff111ab2e1ea14530d 469 SUPERFAMILY SSF55486 243 465 3.22E-50 T 23-04-2016 DC74_RS27515 cb543294685fd4ff111ab2e1ea14530d 469 SUPERFAMILY SSF63737 38 234 6.15E-41 T 23-04-2016 DC74_RS27515 cb543294685fd4ff111ab2e1ea14530d 469 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 218 233 2.1E-12 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS27515 cb543294685fd4ff111ab2e1ea14530d 469 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 171 186 2.1E-12 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS27515 cb543294685fd4ff111ab2e1ea14530d 469 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 336 348 2.1E-12 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS27515 cb543294685fd4ff111ab2e1ea14530d 469 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 317 332 2.1E-12 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS27515 cb543294685fd4ff111ab2e1ea14530d 469 Gene3D G3DSA:1.10.390.10 331 465 1.0E-25 T 23-04-2016 DC74_RS27515 cb543294685fd4ff111ab2e1ea14530d 469 Pfam PF01433 Peptidase family M1 53 401 1.6E-44 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS31715 291120abbfbbd3cb94bf1a2eea96f26f 181 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 90 169 3.9E-33 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS31715 291120abbfbbd3cb94bf1a2eea96f26f 181 PANTHER PTHR10815:SF5 19 170 6.3E-59 T 23-04-2016 DC74_RS31715 291120abbfbbd3cb94bf1a2eea96f26f 181 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 19 85 1.3E-6 T 23-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 DC74_RS31715 291120abbfbbd3cb94bf1a2eea96f26f 181 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 89 168 1.4E-35 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS31715 291120abbfbbd3cb94bf1a2eea96f26f 181 Gene3D G3DSA:1.10.10.10 88 169 1.9E-35 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31715 291120abbfbbd3cb94bf1a2eea96f26f 181 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 13 171 39.728 T 23-04-2016 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 DC74_RS31715 291120abbfbbd3cb94bf1a2eea96f26f 181 SUPERFAMILY SSF46767 88 169 4.19E-33 T 23-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 DC74_RS31715 291120abbfbbd3cb94bf1a2eea96f26f 181 PANTHER PTHR10815 19 170 6.3E-59 T 23-04-2016 DC74_RS31715 291120abbfbbd3cb94bf1a2eea96f26f 181 SUPERFAMILY SSF53155 15 94 1.57E-19 T 23-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 DC74_RS31715 291120abbfbbd3cb94bf1a2eea96f26f 181 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 139 145 - T 23-04-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 SMART SM00382 30 215 2.4E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 SMART SM00382 367 542 3.3E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 SUPERFAMILY SSF52540 340 542 8.84E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 Gene3D G3DSA:3.40.50.300 356 542 4.8E-34 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 SUPERFAMILY SSF52540 17 221 4.43E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 Gene3D G3DSA:3.40.50.300 9 264 2.4E-48 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 Pfam PF00005 ABC transporter 23 171 2.4E-20 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 Pfam PF00005 ABC transporter 360 489 1.7E-18 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 PANTHER PTHR19211 292 538 4.2E-223 T 23-04-2016 DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 PANTHER PTHR19211 1 252 4.2E-223 T 23-04-2016 DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 PANTHER PTHR19211:SF6 292 538 4.2E-223 T 23-04-2016 DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 PANTHER PTHR19211:SF6 1 252 4.2E-223 T 23-04-2016 DC74_RS34570 dc1d18ab42bf18dc0b460311ef74b12e 544 Pfam PF12848 ABC transporter 209 270 1.4E-5 T 23-04-2016 IPR032781 ABC-transporter extension domain DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 PANTHER PTHR11632:SF59 6 133 1.3E-161 T 23-04-2016 DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 PANTHER PTHR11632:SF59 205 551 1.3E-161 T 23-04-2016 DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 PANTHER PTHR11632 6 133 1.3E-161 T 23-04-2016 DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 PANTHER PTHR11632 205 551 1.3E-161 T 23-04-2016 DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 Gene3D G3DSA:3.50.50.60 2 142 3.7E-61 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 Gene3D G3DSA:3.50.50.60 206 313 3.7E-61 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 Gene3D G3DSA:3.50.50.60 491 552 3.7E-61 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 Pfam PF00890 FAD binding domain 10 535 6.3E-85 T 23-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 Gene3D G3DSA:3.90.700.10 329 487 3.0E-34 T 23-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 SUPERFAMILY SSF51905 213 323 3.64E-37 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 SUPERFAMILY SSF51905 3 133 3.64E-37 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 SUPERFAMILY SSF51905 494 552 3.64E-37 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS36450 2394fbca643fb3579824eb7ab9d7eacb 553 SUPERFAMILY SSF56425 314 488 1.07E-34 T 23-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PANTHER PTHR24286:SF42 63 428 6.5E-74 T 23-04-2016 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PANTHER PTHR24286 63 428 6.5E-74 T 23-04-2016 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PRINTS PR00385 P450 superfamily signature 305 316 1.8E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PRINTS PR00385 P450 superfamily signature 380 391 1.8E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PRINTS PR00385 P450 superfamily signature 270 287 1.8E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PRINTS PR00385 P450 superfamily signature 371 380 1.8E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PRINTS PR00359 B-class P450 signature 108 119 3.7E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PRINTS PR00359 B-class P450 signature 305 316 3.7E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PRINTS PR00359 B-class P450 signature 176 191 3.7E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PRINTS PR00359 B-class P450 signature 228 250 3.7E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PRINTS PR00359 B-class P450 signature 380 391 3.7E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PRINTS PR00359 B-class P450 signature 371 380 3.7E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PRINTS PR00359 B-class P450 signature 350 365 3.7E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 PRINTS PR00359 B-class P450 signature 322 349 3.7E-44 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 Pfam PF00067 Cytochrome P450 307 393 3.8E-14 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 373 382 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 SUPERFAMILY SSF48264 26 428 4.71E-74 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37640 2d502ff6473c31bc43a8abaedd8b59eb 430 Gene3D G3DSA:1.10.630.10 21 428 5.1E-98 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS09430 df80419e418fc369e05b02163e00517d 370 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 344 47.038 T 23-04-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09430 df80419e418fc369e05b02163e00517d 370 Gene3D G3DSA:3.20.20.70 1 365 3.0E-130 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS09430 df80419e418fc369e05b02163e00517d 370 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 2 365 1.4E-128 T 23-04-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09430 df80419e418fc369e05b02163e00517d 370 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 300 320 - T 23-04-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 DC74_RS09430 df80419e418fc369e05b02163e00517d 370 SUPERFAMILY SSF51395 1 364 7.33E-103 T 23-04-2016 DC74_RS09430 df80419e418fc369e05b02163e00517d 370 Pfam PF01180 Dihydroorotate dehydrogenase 50 348 1.6E-95 T 23-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 DC74_RS09430 df80419e418fc369e05b02163e00517d 370 PANTHER PTHR11938:SF105 1 361 1.9E-113 T 23-04-2016 DC74_RS09430 df80419e418fc369e05b02163e00517d 370 PANTHER PTHR11938 1 361 1.9E-113 T 23-04-2016 DC74_RS04780 dbeccccccb03dbadb81a1b5353ddc93e 306 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 14 76 8.6E-8 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS04780 dbeccccccb03dbadb81a1b5353ddc93e 306 PANTHER PTHR11695 1 297 2.3E-121 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS04780 dbeccccccb03dbadb81a1b5353ddc93e 306 SUPERFAMILY SSF51735 103 224 4.87E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04780 dbeccccccb03dbadb81a1b5353ddc93e 306 Gene3D G3DSA:3.40.50.720 137 223 3.6E-19 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04780 dbeccccccb03dbadb81a1b5353ddc93e 306 Pfam PF00107 Zinc-binding dehydrogenase 142 223 1.1E-15 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS04780 dbeccccccb03dbadb81a1b5353ddc93e 306 SMART SM00829 1 286 9.4E-15 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS04780 dbeccccccb03dbadb81a1b5353ddc93e 306 SUPERFAMILY SSF50129 1 136 1.08E-29 T 23-04-2016 IPR011032 GroES-like DC74_RS04780 dbeccccccb03dbadb81a1b5353ddc93e 306 PANTHER PTHR11695:SF533 1 297 2.3E-121 T 23-04-2016 DC74_RS04780 dbeccccccb03dbadb81a1b5353ddc93e 306 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 131 152 - T 23-04-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 DC74_RS04780 dbeccccccb03dbadb81a1b5353ddc93e 306 Gene3D G3DSA:3.90.180.10 2 136 1.2E-37 T 23-04-2016 IPR011032 GroES-like DC74_RS02700 4db2775dce10fe5cdee30708a3079de3 293 PANTHER PTHR10992:SF771 34 293 1.3E-36 T 23-04-2016 DC74_RS02700 4db2775dce10fe5cdee30708a3079de3 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 241 255 1.3E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS02700 4db2775dce10fe5cdee30708a3079de3 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 150 163 1.3E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS02700 4db2775dce10fe5cdee30708a3079de3 293 PRINTS PR00111 Alpha/beta hydrolase fold signature 136 149 1.3E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS02700 4db2775dce10fe5cdee30708a3079de3 293 Pfam PF12697 Alpha/beta hydrolase family 68 282 1.6E-15 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS02700 4db2775dce10fe5cdee30708a3079de3 293 Gene3D G3DSA:3.40.50.1820 27 291 3.2E-52 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02700 4db2775dce10fe5cdee30708a3079de3 293 PANTHER PTHR10992 34 293 1.3E-36 T 23-04-2016 DC74_RS02700 4db2775dce10fe5cdee30708a3079de3 293 SUPERFAMILY SSF53474 38 292 2.47E-44 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS07720 b0b3ae77754170331c57a5f329a868b0 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 8.8E-9 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS07720 b0b3ae77754170331c57a5f329a868b0 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 8.8E-9 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS07720 b0b3ae77754170331c57a5f329a868b0 229 SMART SM00895 94 221 1.0E-19 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS07720 b0b3ae77754170331c57a5f329a868b0 229 SUPERFAMILY SSF46785 6 78 7.21E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07720 b0b3ae77754170331c57a5f329a868b0 229 Pfam PF07729 FCD domain 94 216 7.0E-24 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS07720 b0b3ae77754170331c57a5f329a868b0 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 4.6E-21 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS07720 b0b3ae77754170331c57a5f329a868b0 229 SMART SM00345 15 74 6.1E-18 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS07720 b0b3ae77754170331c57a5f329a868b0 229 Gene3D G3DSA:1.10.10.10 8 80 2.3E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07720 b0b3ae77754170331c57a5f329a868b0 229 PANTHER PTHR11751 11 110 4.0E-28 T 23-04-2016 DC74_RS07720 b0b3ae77754170331c57a5f329a868b0 229 Gene3D G3DSA:1.20.120.530 90 226 4.4E-26 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS07720 b0b3ae77754170331c57a5f329a868b0 229 SUPERFAMILY SSF48008 92 227 1.36E-23 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS07720 b0b3ae77754170331c57a5f329a868b0 229 PANTHER PTHR11751:SF342 11 110 4.0E-28 T 23-04-2016 DC74_RS04245 d2359df713e677702b637e67566b1d76 525 SUPERFAMILY SSF81296 415 524 4.06E-23 T 23-04-2016 IPR014756 Immunoglobulin E-set DC74_RS04245 d2359df713e677702b637e67566b1d76 525 SUPERFAMILY SSF56524 229 423 1.44E-49 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS04245 d2359df713e677702b637e67566b1d76 525 Pfam PF00174 Oxidoreductase molybdopterin binding domain 246 398 5.0E-34 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS04245 d2359df713e677702b637e67566b1d76 525 PANTHER PTHR19372 228 504 1.1E-61 T 23-04-2016 DC74_RS04245 d2359df713e677702b637e67566b1d76 525 PRINTS PR00407 Eukaryotic molybdopterin domain signature 348 364 3.6E-8 T 23-04-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 DC74_RS04245 d2359df713e677702b637e67566b1d76 525 PRINTS PR00407 Eukaryotic molybdopterin domain signature 297 312 3.6E-8 T 23-04-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 DC74_RS04245 d2359df713e677702b637e67566b1d76 525 PRINTS PR00407 Eukaryotic molybdopterin domain signature 365 378 3.6E-8 T 23-04-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 DC74_RS04245 d2359df713e677702b637e67566b1d76 525 Gene3D G3DSA:2.60.40.650 421 524 1.2E-20 T 23-04-2016 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 DC74_RS04245 d2359df713e677702b637e67566b1d76 525 Gene3D G3DSA:3.90.420.10 227 420 1.1E-47 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS15665 e88d7f2bd9abf338f3c07e3b700f283b 338 Gene3D G3DSA:3.40.50.1820 76 321 1.8E-29 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS15665 e88d7f2bd9abf338f3c07e3b700f283b 338 Gene3D G3DSA:3.40.50.1820 10 32 1.8E-29 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS15665 e88d7f2bd9abf338f3c07e3b700f283b 338 SUPERFAMILY SSF53474 82 313 1.29E-21 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS15665 e88d7f2bd9abf338f3c07e3b700f283b 338 Pfam PF00756 Putative esterase 94 312 1.3E-12 T 23-04-2016 IPR000801 Putative esterase DC74_RS32775 8278c0612f3a5bf4cdee0833b3d2c380 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 65 6.6E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS32775 8278c0612f3a5bf4cdee0833b3d2c380 212 SUPERFAMILY SSF46689 9 80 6.67E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS32775 8278c0612f3a5bf4cdee0833b3d2c380 212 Gene3D G3DSA:1.10.10.60 10 65 2.9E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS32775 8278c0612f3a5bf4cdee0833b3d2c380 212 Gene3D G3DSA:1.10.357.10 66 207 1.4E-19 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS32775 8278c0612f3a5bf4cdee0833b3d2c380 212 PANTHER PTHR30055:SF54 4 172 9.3E-41 T 23-04-2016 DC74_RS32775 8278c0612f3a5bf4cdee0833b3d2c380 212 PANTHER PTHR30055 4 172 9.3E-41 T 23-04-2016 DC74_RS39485 3487be4e14775032930c33f88d834f3a 300 Pfam PF03466 LysR substrate binding domain 91 298 1.3E-44 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS39485 3487be4e14775032930c33f88d834f3a 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 3.1E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS39485 3487be4e14775032930c33f88d834f3a 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 3.1E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS39485 3487be4e14775032930c33f88d834f3a 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 3.1E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS39485 3487be4e14775032930c33f88d834f3a 300 PANTHER PTHR30126:SF11 4 298 2.1E-80 T 23-04-2016 DC74_RS39485 3487be4e14775032930c33f88d834f3a 300 Gene3D G3DSA:1.10.10.10 4 87 1.7E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39485 3487be4e14775032930c33f88d834f3a 300 Gene3D G3DSA:3.40.190.10 175 266 3.5E-20 T 23-04-2016 DC74_RS39485 3487be4e14775032930c33f88d834f3a 300 Gene3D G3DSA:3.40.190.10 94 174 4.3E-17 T 23-04-2016 DC74_RS39485 3487be4e14775032930c33f88d834f3a 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 3.0E-17 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS39485 3487be4e14775032930c33f88d834f3a 300 SUPERFAMILY SSF46785 4 114 4.39E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39485 3487be4e14775032930c33f88d834f3a 300 PANTHER PTHR30126 4 298 2.1E-80 T 23-04-2016 DC74_RS39485 3487be4e14775032930c33f88d834f3a 300 SUPERFAMILY SSF53850 94 298 8.54E-39 T 23-04-2016 DC74_RS18795 4067d88ee62cbeb8417a5a2590f66ec7 238 Gene3D G3DSA:3.30.190.20 16 67 4.6E-45 T 23-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 DC74_RS18795 4067d88ee62cbeb8417a5a2590f66ec7 238 Gene3D G3DSA:3.30.190.20 160 225 4.6E-45 T 23-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 DC74_RS18795 4067d88ee62cbeb8417a5a2590f66ec7 238 PANTHER PTHR23105 16 236 1.8E-78 T 23-04-2016 DC74_RS18795 4067d88ee62cbeb8417a5a2590f66ec7 238 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 228 42.87 T 23-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 DC74_RS18795 4067d88ee62cbeb8417a5a2590f66ec7 238 Gene3D G3DSA:3.40.50.790 68 158 4.8E-41 T 23-04-2016 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich DC74_RS18795 4067d88ee62cbeb8417a5a2590f66ec7 238 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 2 226 2.9E-101 T 23-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 DC74_RS18795 4067d88ee62cbeb8417a5a2590f66ec7 238 PANTHER PTHR23105:SF5 16 236 1.8E-78 T 23-04-2016 DC74_RS18795 4067d88ee62cbeb8417a5a2590f66ec7 238 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 7.3E-53 T 23-04-2016 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein DC74_RS18795 4067d88ee62cbeb8417a5a2590f66ec7 238 SUPERFAMILY SSF56808 6 226 1.44E-81 T 23-04-2016 IPR023674 Ribosomal protein L1-like DC74_RS18795 4067d88ee62cbeb8417a5a2590f66ec7 238 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 138 - T 23-04-2016 IPR023673 Ribosomal protein L1, conserved site DC74_RS18795 4067d88ee62cbeb8417a5a2590f66ec7 238 PIRSF PIRSF002155 1 226 3.6E-73 T 23-04-2016 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 DC74_RS21195 4870c63c437552a24d71debe1ee3136f 218 PANTHER PTHR12151:SF0 1 214 1.1E-44 T 23-04-2016 DC74_RS21195 4870c63c437552a24d71debe1ee3136f 218 SUPERFAMILY SSF52833 54 213 8.61E-36 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS21195 4870c63c437552a24d71debe1ee3136f 218 Pfam PF02630 SCO1/SenC 53 186 3.4E-29 T 23-04-2016 IPR003782 Copper chaperone SCO1/SenC DC74_RS21195 4870c63c437552a24d71debe1ee3136f 218 Gene3D G3DSA:3.40.30.10 15 215 4.3E-44 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS21195 4870c63c437552a24d71debe1ee3136f 218 PANTHER PTHR12151 1 214 1.1E-44 T 23-04-2016 IPR003782 Copper chaperone SCO1/SenC DC74_RS14115 c45f659bb6e52d423fcb546fa849bae8 340 Gene3D G3DSA:3.40.50.720 145 306 8.3E-70 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS14115 c45f659bb6e52d423fcb546fa849bae8 340 Pfam PF16884 N-terminal domain of oxidoreductase 10 115 2.1E-42 T 23-04-2016 DC74_RS14115 c45f659bb6e52d423fcb546fa849bae8 340 SMART SM00829 22 336 3.2E-8 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS14115 c45f659bb6e52d423fcb546fa849bae8 340 Pfam PF00107 Zinc-binding dehydrogenase 162 290 4.9E-22 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS14115 c45f659bb6e52d423fcb546fa849bae8 340 PANTHER PTHR11695 27 340 1.1E-127 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS14115 c45f659bb6e52d423fcb546fa849bae8 340 Gene3D G3DSA:3.90.180.10 6 144 6.5E-54 T 23-04-2016 IPR011032 GroES-like DC74_RS14115 c45f659bb6e52d423fcb546fa849bae8 340 SUPERFAMILY SSF50129 7 144 3.14E-42 T 23-04-2016 IPR011032 GroES-like DC74_RS14115 c45f659bb6e52d423fcb546fa849bae8 340 SUPERFAMILY SSF51735 127 303 2.74E-49 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS14115 c45f659bb6e52d423fcb546fa849bae8 340 PANTHER PTHR11695:SF528 27 340 1.1E-127 T 23-04-2016 DC74_RS23800 7ee49de07b13941c9d92781054bba7fc 223 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 2 200 2.8E-15 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS23800 7ee49de07b13941c9d92781054bba7fc 223 Gene3D G3DSA:3.40.50.1110 2 214 2.5E-22 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS23800 7ee49de07b13941c9d92781054bba7fc 223 PANTHER PTHR30383:SF3 1 39 7.1E-22 T 23-04-2016 DC74_RS23800 7ee49de07b13941c9d92781054bba7fc 223 PANTHER PTHR30383:SF3 58 221 7.1E-22 T 23-04-2016 DC74_RS23800 7ee49de07b13941c9d92781054bba7fc 223 SUPERFAMILY SSF52266 2 35 1.24E-22 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS23800 7ee49de07b13941c9d92781054bba7fc 223 SUPERFAMILY SSF52266 66 215 1.24E-22 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS23800 7ee49de07b13941c9d92781054bba7fc 223 PANTHER PTHR30383 1 39 7.1E-22 T 23-04-2016 DC74_RS23800 7ee49de07b13941c9d92781054bba7fc 223 PANTHER PTHR30383 58 221 7.1E-22 T 23-04-2016 DC74_RS35875 5a52e104899443140d1377c22ed18391 126 PIRSF PIRSF004761 1 116 4.4E-29 T 23-04-2016 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 DC74_RS35875 5a52e104899443140d1377c22ed18391 126 PANTHER PTHR34535 2 116 8.2E-35 T 23-04-2016 DC74_RS35875 5a52e104899443140d1377c22ed18391 126 Hamap MF_00213 Probable hydrogenase nickel incorporation protein HypA [hypA]. 1 114 21.298 T 23-04-2016 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 DC74_RS35875 5a52e104899443140d1377c22ed18391 126 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 111 7.2E-31 T 23-04-2016 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 DC74_RS02415 3575c340712f47d52cc357f72273cdd0 499 Pfam PF07730 Histidine kinase 110 174 1.1E-13 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS02415 3575c340712f47d52cc357f72273cdd0 499 PANTHER PTHR24421 7 326 7.9E-63 T 23-04-2016 DC74_RS02415 3575c340712f47d52cc357f72273cdd0 499 SUPERFAMILY SSF55874 199 314 2.84E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS02415 3575c340712f47d52cc357f72273cdd0 499 PANTHER PTHR24421:SF26 7 326 7.9E-63 T 23-04-2016 DC74_RS02415 3575c340712f47d52cc357f72273cdd0 499 Gene3D G3DSA:3.30.565.10 197 321 6.9E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 Gene3D G3DSA:1.10.150.120 85 199 5.7E-30 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 73 1.7E-8 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 Gene3D G3DSA:3.10.20.30 4 84 5.1E-27 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 Gene3D G3DSA:3.30.390.50 381 480 2.4E-32 T 23-04-2016 DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 SUPERFAMILY SSF47741 100 197 1.01E-24 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 Gene3D G3DSA:3.30.465.10 261 373 5.6E-37 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 SUPERFAMILY SSF55447 379 480 2.88E-30 T 23-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 Pfam PF01799 [2Fe-2S] binding domain 83 175 2.4E-25 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 SUPERFAMILY SSF54292 4 88 7.87E-17 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 380 476 1.1E-26 T 23-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 Gene3D G3DSA:3.30.43.10 203 260 3.5E-11 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 SUPERFAMILY SSF56176 203 373 3.6E-51 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 SMART SM01092 380 481 2.4E-28 T 23-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 PANTHER PTHR11908 3 469 3.1E-120 T 23-04-2016 DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 210 373 1.6E-48 T 23-04-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DC74_RS02450 a526f7d7e2af3e6e660e159fb27e0dc9 487 PIRSF PIRSF036557 1 487 2.8E-200 T 23-04-2016 IPR012175 Xanthine dehydrogenase, small subunit, bacteria DC74_RS10420 c442a54c8f28f0a800b227fa83b8f028 283 PANTHER PTHR21240:SF1 1 278 3.8E-62 T 23-04-2016 DC74_RS10420 c442a54c8f28f0a800b227fa83b8f028 283 PANTHER PTHR21240 1 278 3.8E-62 T 23-04-2016 DC74_RS10420 c442a54c8f28f0a800b227fa83b8f028 283 SUPERFAMILY SSF51556 3 275 1.5E-70 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS10420 c442a54c8f28f0a800b227fa83b8f028 283 Pfam PF04909 Amidohydrolase 3 274 4.8E-45 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS10420 c442a54c8f28f0a800b227fa83b8f028 283 Gene3D G3DSA:3.20.20.140 1 276 3.6E-77 T 23-04-2016 DC74_RS39820 c5447032d556410c0906ebd7a4682d13 136 PANTHER PTHR11803 29 133 9.6E-18 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS39820 c5447032d556410c0906ebd7a4682d13 136 Pfam PF01042 Endoribonuclease L-PSP 17 133 2.5E-13 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS39820 c5447032d556410c0906ebd7a4682d13 136 Gene3D G3DSA:3.30.1330.40 16 133 3.5E-24 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS39820 c5447032d556410c0906ebd7a4682d13 136 SUPERFAMILY SSF55298 17 133 3.46E-20 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS39820 c5447032d556410c0906ebd7a4682d13 136 PANTHER PTHR11803:SF9 29 133 9.6E-18 T 23-04-2016 DC74_RS07845 563f3c704811dd18f4936c83f5198e8e 520 Pfam PF10756 Bacterial PH domain 66 127 2.4E-6 T 23-04-2016 IPR019692 Protein of unknown function DUF2581 DC74_RS36900 4cb15e8f695d954cddaae003025c2811 263 Pfam PF00005 ABC transporter 23 171 3.3E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS36900 4cb15e8f695d954cddaae003025c2811 263 SMART SM00382 31 219 5.0E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS36900 4cb15e8f695d954cddaae003025c2811 263 Gene3D G3DSA:3.40.50.300 6 240 8.4E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36900 4cb15e8f695d954cddaae003025c2811 263 PANTHER PTHR24220 8 258 4.4E-104 T 23-04-2016 DC74_RS36900 4cb15e8f695d954cddaae003025c2811 263 SUPERFAMILY SSF52540 7 235 9.4E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36900 4cb15e8f695d954cddaae003025c2811 263 PANTHER PTHR24220:SF266 8 258 4.4E-104 T 23-04-2016 DC74_RS34530 7c0f497da9d59e1945676c675786b357 239 SUPERFAMILY SSF56784 12 213 1.06E-46 T 23-04-2016 IPR023214 HAD-like domain DC74_RS34530 7c0f497da9d59e1945676c675786b357 239 PANTHER PTHR18901 8 214 4.1E-52 T 23-04-2016 DC74_RS34530 7c0f497da9d59e1945676c675786b357 239 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 129 192 1.6E-15 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34530 7c0f497da9d59e1945676c675786b357 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 7.3E-5 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34530 7c0f497da9d59e1945676c675786b357 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 11 22 7.3E-5 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34530 7c0f497da9d59e1945676c675786b357 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 174 7.3E-5 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34530 7c0f497da9d59e1945676c675786b357 239 Gene3D G3DSA:3.40.50.1000 97 213 7.8E-38 T 23-04-2016 IPR023214 HAD-like domain DC74_RS34530 7c0f497da9d59e1945676c675786b357 239 Gene3D G3DSA:3.40.50.1000 11 25 7.8E-38 T 23-04-2016 IPR023214 HAD-like domain DC74_RS34530 7c0f497da9d59e1945676c675786b357 239 PANTHER PTHR18901:SF9 8 214 4.1E-52 T 23-04-2016 DC74_RS34530 7c0f497da9d59e1945676c675786b357 239 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 192 5.9E-27 T 23-04-2016 IPR023214 HAD-like domain DC74_RS00450 371ead33ff7fc5eba9368953b4e6aa39 297 PANTHER PTHR30346:SF2 1 296 4.5E-70 T 23-04-2016 DC74_RS00450 371ead33ff7fc5eba9368953b4e6aa39 297 Pfam PF03466 LysR substrate binding domain 93 293 3.5E-27 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS00450 371ead33ff7fc5eba9368953b4e6aa39 297 Gene3D G3DSA:1.10.10.10 6 84 2.8E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00450 371ead33ff7fc5eba9368953b4e6aa39 297 SUPERFAMILY SSF53850 92 295 1.92E-24 T 23-04-2016 DC74_RS00450 371ead33ff7fc5eba9368953b4e6aa39 297 PANTHER PTHR30346 1 296 4.5E-70 T 23-04-2016 DC74_RS00450 371ead33ff7fc5eba9368953b4e6aa39 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 7.1E-19 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00450 371ead33ff7fc5eba9368953b4e6aa39 297 Gene3D G3DSA:3.40.190.10 94 183 2.6E-16 T 23-04-2016 DC74_RS00450 371ead33ff7fc5eba9368953b4e6aa39 297 SUPERFAMILY SSF46785 7 112 1.09E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00450 371ead33ff7fc5eba9368953b4e6aa39 297 Gene3D G3DSA:3.40.190.10 184 269 9.4E-12 T 23-04-2016 DC74_RS00450 371ead33ff7fc5eba9368953b4e6aa39 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 5.5E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00450 371ead33ff7fc5eba9368953b4e6aa39 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 5.5E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00450 371ead33ff7fc5eba9368953b4e6aa39 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 5.5E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS17630 9479f83324cb802aca4995464d4a0dee 299 PANTHER PTHR10060 12 93 1.4E-109 T 23-04-2016 IPR001130 TatD family GO:0016788 DC74_RS17630 9479f83324cb802aca4995464d4a0dee 299 PANTHER PTHR10060 118 299 1.4E-109 T 23-04-2016 IPR001130 TatD family GO:0016788 DC74_RS17630 9479f83324cb802aca4995464d4a0dee 299 PANTHER PTHR10060:SF20 12 93 1.4E-109 T 23-04-2016 DC74_RS17630 9479f83324cb802aca4995464d4a0dee 299 PANTHER PTHR10060:SF20 118 299 1.4E-109 T 23-04-2016 DC74_RS17630 9479f83324cb802aca4995464d4a0dee 299 PIRSF PIRSF005902 12 299 2.7E-65 T 23-04-2016 IPR001130 TatD family GO:0016788 DC74_RS17630 9479f83324cb802aca4995464d4a0dee 299 SUPERFAMILY SSF51556 19 89 7.64E-70 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS17630 9479f83324cb802aca4995464d4a0dee 299 SUPERFAMILY SSF51556 119 298 7.64E-70 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS17630 9479f83324cb802aca4995464d4a0dee 299 Pfam PF01026 TatD related DNase 22 297 6.4E-66 T 23-04-2016 IPR001130 TatD family GO:0016788 DC74_RS17630 9479f83324cb802aca4995464d4a0dee 299 Gene3D G3DSA:3.20.20.140 12 298 3.1E-77 T 23-04-2016 DC74_RS29660 e186dfc62e34962f2c3b3d32f0e7a6f6 100 SUPERFAMILY SSF46955 20 72 5.86E-10 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS29660 e186dfc62e34962f2c3b3d32f0e7a6f6 100 Gene3D G3DSA:1.10.10.10 20 75 1.4E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29660 e186dfc62e34962f2c3b3d32f0e7a6f6 100 Pfam PF12728 Helix-turn-helix domain 20 72 3.5E-14 T 23-04-2016 DC74_RS21480 6d80fa2824f9c33727dd84fdfc2dedd8 292 PANTHER PTHR21240 20 291 1.0E-21 T 23-04-2016 DC74_RS21480 6d80fa2824f9c33727dd84fdfc2dedd8 292 Gene3D G3DSA:3.20.20.140 19 291 1.4E-61 T 23-04-2016 DC74_RS21480 6d80fa2824f9c33727dd84fdfc2dedd8 292 Pfam PF04909 Amidohydrolase 21 291 7.4E-36 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS21480 6d80fa2824f9c33727dd84fdfc2dedd8 292 SUPERFAMILY SSF51556 20 291 6.17E-54 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS39580 1b329c1fb8cbd5e9c9e2648523870b1a 532 Gene3D G3DSA:2.160.20.10 107 224 1.2E-11 T 23-04-2016 IPR012334 Pectin lyase fold DC74_RS39580 1b329c1fb8cbd5e9c9e2648523870b1a 532 Gene3D G3DSA:2.160.20.10 313 369 1.2E-11 T 23-04-2016 IPR012334 Pectin lyase fold DC74_RS39580 1b329c1fb8cbd5e9c9e2648523870b1a 532 SUPERFAMILY SSF51126 100 193 1.36E-12 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS39580 1b329c1fb8cbd5e9c9e2648523870b1a 532 SUPERFAMILY SSF51126 379 472 1.36E-12 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS39580 1b329c1fb8cbd5e9c9e2648523870b1a 532 SUPERFAMILY SSF51126 285 347 1.36E-12 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS12220 90a2d3c782cbb5e26e0e589ffd89e229 231 Pfam PF12697 Alpha/beta hydrolase family 16 223 1.5E-16 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS12220 90a2d3c782cbb5e26e0e589ffd89e229 231 Gene3D G3DSA:3.40.50.1820 2 231 3.4E-29 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS12220 90a2d3c782cbb5e26e0e589ffd89e229 231 SUPERFAMILY SSF53474 2 231 8.11E-32 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS12220 90a2d3c782cbb5e26e0e589ffd89e229 231 PANTHER PTHR10992 2 231 3.2E-22 T 23-04-2016 DC74_RS04035 5e74dc11d9ee4c6562e7632f6901dd59 330 SUPERFAMILY SSF51430 1 315 5.63E-100 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS04035 5e74dc11d9ee4c6562e7632f6901dd59 330 PANTHER PTHR11732 1 327 3.1E-179 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS04035 5e74dc11d9ee4c6562e7632f6901dd59 330 Gene3D G3DSA:3.20.20.100 1 322 1.2E-112 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS04035 5e74dc11d9ee4c6562e7632f6901dd59 330 PANTHER PTHR11732:SF215 1 327 3.1E-179 T 23-04-2016 DC74_RS04035 5e74dc11d9ee4c6562e7632f6901dd59 330 Pfam PF00248 Aldo/keto reductase family 15 309 8.4E-74 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS17345 b6f90aae0a4fe4edf6d649dabed09a7a 313 Gene3D G3DSA:3.30.420.150 135 312 1.4E-59 T 23-04-2016 DC74_RS17345 b6f90aae0a4fe4edf6d649dabed09a7a 313 PANTHER PTHR30005:SF1 3 313 4.1E-135 T 23-04-2016 DC74_RS17345 b6f90aae0a4fe4edf6d649dabed09a7a 313 Pfam PF02541 Ppx/GppA phosphatase family 26 309 2.6E-56 T 23-04-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40|UniPathway: UPA00908 DC74_RS17345 b6f90aae0a4fe4edf6d649dabed09a7a 313 SUPERFAMILY SSF53067 3 124 3.02E-33 T 23-04-2016 DC74_RS17345 b6f90aae0a4fe4edf6d649dabed09a7a 313 Gene3D G3DSA:3.30.420.40 2 125 4.4E-50 T 23-04-2016 DC74_RS17345 b6f90aae0a4fe4edf6d649dabed09a7a 313 SUPERFAMILY SSF53067 135 312 1.94E-39 T 23-04-2016 DC74_RS17345 b6f90aae0a4fe4edf6d649dabed09a7a 313 PANTHER PTHR30005 3 313 4.1E-135 T 23-04-2016 DC74_RS29355 fcbe66289791230a5630a520f032d3f8 275 Gene3D G3DSA:1.10.12.10 217 275 4.0E-23 T 23-04-2016 IPR014748 Crontonase, C-terminal DC74_RS29355 fcbe66289791230a5630a520f032d3f8 275 PANTHER PTHR11941 2 272 2.4E-169 T 23-04-2016 DC74_RS29355 fcbe66289791230a5630a520f032d3f8 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 274 7.1E-53 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS29355 fcbe66289791230a5630a520f032d3f8 275 PANTHER PTHR11941:SF90 2 272 2.4E-169 T 23-04-2016 DC74_RS29355 fcbe66289791230a5630a520f032d3f8 275 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 115 135 - T 23-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 DC74_RS29355 fcbe66289791230a5630a520f032d3f8 275 Gene3D G3DSA:3.90.226.10 15 216 6.3E-59 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS29355 fcbe66289791230a5630a520f032d3f8 275 SUPERFAMILY SSF52096 14 274 3.73E-77 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS14205 79b27d6a8d45e6424ea4734b944cf4b1 266 SUPERFAMILY SSF56281 8 245 1.6E-23 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS14205 79b27d6a8d45e6424ea4734b944cf4b1 266 Gene3D G3DSA:3.60.15.10 4 229 4.1E-30 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS18300 31e05031b86e17ec50b28a17c3023845 215 SUPERFAMILY SSF46689 15 76 1.56E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS18300 31e05031b86e17ec50b28a17c3023845 215 SUPERFAMILY SSF48498 93 196 1.33E-6 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS18300 31e05031b86e17ec50b28a17c3023845 215 PANTHER PTHR30328 14 197 1.5E-28 T 23-04-2016 DC74_RS18300 31e05031b86e17ec50b28a17c3023845 215 Gene3D G3DSA:1.10.357.10 12 204 2.1E-24 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS18300 31e05031b86e17ec50b28a17c3023845 215 PANTHER PTHR30328:SF6 14 197 1.5E-28 T 23-04-2016 DC74_RS18300 31e05031b86e17ec50b28a17c3023845 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 62 8.7E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS06810 14b16899d5358f8d114b0bfc1434d5f7 373 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 266 276 - T 23-04-2016 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 DC74_RS06810 14b16899d5358f8d114b0bfc1434d5f7 373 PANTHER PTHR31126 234 371 2.5E-53 T 23-04-2016 DC74_RS06810 14b16899d5358f8d114b0bfc1434d5f7 373 PANTHER PTHR31126 113 212 2.5E-53 T 23-04-2016 DC74_RS06810 14b16899d5358f8d114b0bfc1434d5f7 373 Pfam PF13350 Tyrosine phosphatase family 134 371 1.2E-67 T 23-04-2016 IPR026893 Tyrosine/serine-protein phosphatase IphP-type DC74_RS06810 14b16899d5358f8d114b0bfc1434d5f7 373 SUPERFAMILY SSF52799 133 371 4.65E-53 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS06810 14b16899d5358f8d114b0bfc1434d5f7 373 PANTHER PTHR31126:SF21 234 371 2.5E-53 T 23-04-2016 DC74_RS06810 14b16899d5358f8d114b0bfc1434d5f7 373 PANTHER PTHR31126:SF21 113 212 2.5E-53 T 23-04-2016 DC74_RS06810 14b16899d5358f8d114b0bfc1434d5f7 373 Gene3D G3DSA:3.90.190.10 137 305 1.1E-16 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 2.0E-32 T 23-04-2016 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 Gene3D G3DSA:2.40.50.140 1 115 8.1E-52 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 SMART SM01383 42 119 1.1E-39 T 23-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 SUPERFAMILY SSF50104 127 271 2.11E-56 T 23-04-2016 IPR008991 Translation protein SH3-like domain DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 PIRSF PIRSF002158 4 275 4.0E-94 T 23-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 PANTHER PTHR13691 1 278 1.4E-139 T 23-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 23-04-2016 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 SMART SM01382 125 253 5.6E-89 T 23-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 Gene3D G3DSA:2.30.30.30 120 196 2.1E-30 T 23-04-2016 IPR014722 Ribosomal protein L2 domain 2 DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 SUPERFAMILY SSF50249 3 126 5.14E-49 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 3.1E-55 T 23-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 Gene3D G3DSA:4.10.950.10 197 273 4.8E-32 T 23-04-2016 IPR014726 Ribosomal protein L2, domain 3 DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 7.7E-128 T 23-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 DC74_RS18720 af3fb7ae364bb947bfd824f157b9dcd0 278 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 48.019 T 23-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 Gene3D G3DSA:3.30.390.30 331 395 3.0E-11 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 PANTHER PTHR22912:SF180 2 395 3.1E-67 T 23-04-2016 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 98 106 3.6E-9 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 230 251 3.6E-9 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 137 161 3.6E-9 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 3.6E-9 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 Gene3D G3DSA:3.50.50.60 101 316 1.7E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 308 8.0E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 SUPERFAMILY SSF55424 323 396 3.98E-14 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 SUPERFAMILY SSF51905 140 318 7.11E-23 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.5E-15 T 23-04-2016 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 3.5E-15 T 23-04-2016 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 3.5E-15 T 23-04-2016 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 3.5E-15 T 23-04-2016 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 Pfam PF14759 Reductase C-terminal 331 397 1.5E-7 T 23-04-2016 IPR028202 Reductase, C-terminal DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 PANTHER PTHR22912 2 395 3.1E-67 T 23-04-2016 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 Gene3D G3DSA:3.50.50.60 3 100 2.0E-24 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS22820 71d5b1e267016a92f042e4d82573f848 399 SUPERFAMILY SSF51905 3 183 8.42E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 PRINTS PR00732 Glycosyl hydrolase family 4 signature 185 197 9.9E-35 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 9.9E-35 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 PRINTS PR00732 Glycosyl hydrolase family 4 signature 135 152 9.9E-35 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 9.9E-35 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 9.9E-35 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 9.9E-35 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 PANTHER PTHR32092 368 489 6.3E-171 T 23-04-2016 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 PANTHER PTHR32092 1 295 6.3E-171 T 23-04-2016 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 SUPERFAMILY SSF56327 163 311 3.63E-29 T 23-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 Gene3D G3DSA:3.90.110.10 384 487 4.7E-31 T 23-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 PANTHER PTHR32092:SF5 368 489 6.3E-171 T 23-04-2016 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 PANTHER PTHR32092:SF5 1 295 6.3E-171 T 23-04-2016 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 Pfam PF02056 Family 4 glycosyl hydrolase 2 179 3.9E-46 T 23-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 SUPERFAMILY SSF51735 1 157 4.66E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 SUPERFAMILY SSF56327 385 487 5.27E-26 T 23-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 Gene3D G3DSA:3.90.110.10 162 310 1.3E-48 T 23-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 385 466 5.6E-21 T 23-04-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 190 310 9.5E-13 T 23-04-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 DC74_RS15510 4a604f884b091359298d079a2c25dd3d 490 Gene3D G3DSA:3.40.50.720 1 159 7.7E-56 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 SUPERFAMILY SSF51905 4 98 1.15E-47 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 SUPERFAMILY SSF51905 142 350 1.15E-47 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 6.3E-53 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 437 6.3E-53 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 444 464 6.3E-53 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 292 6.3E-53 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 166 6.3E-53 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 6.3E-53 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 357 378 6.3E-53 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 321 328 6.3E-53 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 193 218 6.3E-53 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 5.2E-34 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 277 293 5.2E-34 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 193 211 5.2E-34 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 306 328 5.2E-34 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.2E-34 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PANTHER PTHR22912 1 130 3.3E-160 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PANTHER PTHR22912 152 473 3.3E-160 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 SUPERFAMILY SSF55424 357 475 4.47E-28 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 Gene3D G3DSA:3.50.50.60 5 158 1.1E-25 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PIRSF PIRSF000350 1 475 5.6E-75 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 341 1.7E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 Gene3D G3DSA:3.30.390.30 356 474 5.9E-31 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 Gene3D G3DSA:3.50.50.60 159 349 4.0E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PANTHER PTHR22912:SF20 1 130 3.3E-160 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 PANTHER PTHR22912:SF20 152 473 3.3E-160 T 23-04-2016 DC74_RS25070 4f7bdfba0cf60c3b2576468bce888c71 481 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 363 468 1.0E-22 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS20990 95d0da77ff08413f04654c7a49c09154 351 PANTHER PTHR24032 68 225 1.9E-17 T 23-04-2016 DC74_RS20990 95d0da77ff08413f04654c7a49c09154 351 Gene3D G3DSA:3.60.21.10 78 347 9.0E-36 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS20990 95d0da77ff08413f04654c7a49c09154 351 SUPERFAMILY SSF56300 82 338 2.64E-37 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS20990 95d0da77ff08413f04654c7a49c09154 351 PRINTS PR00114 Serine/threonine phosphatase family signature 83 110 2.0E-6 T 23-04-2016 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 DC74_RS20990 95d0da77ff08413f04654c7a49c09154 351 PRINTS PR00114 Serine/threonine phosphatase family signature 120 147 2.0E-6 T 23-04-2016 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04660+3.1.3.16 DC74_RS20990 95d0da77ff08413f04654c7a49c09154 351 Pfam PF00149 Calcineurin-like phosphoesterase 83 299 3.0E-9 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS10335 834c00747f569614774908eb2dc35227 97 SUPERFAMILY SSF54862 11 82 1.01E-9 T 23-04-2016 DC74_RS10335 834c00747f569614774908eb2dc35227 97 PANTHER PTHR39163 9 95 1.0E-26 T 23-04-2016 DC74_RS10335 834c00747f569614774908eb2dc35227 97 Pfam PF13459 4Fe-4S single cluster domain 12 82 4.8E-19 T 23-04-2016 DC74_RS10335 834c00747f569614774908eb2dc35227 97 Gene3D G3DSA:3.30.70.20 10 94 2.2E-28 T 23-04-2016 DC74_RS10335 834c00747f569614774908eb2dc35227 97 PANTHER PTHR39163:SF1 9 95 1.0E-26 T 23-04-2016 DC74_RS10335 834c00747f569614774908eb2dc35227 97 PRINTS PR00352 3Fe-4S ferredoxin signature 25 35 9.3E-7 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS10335 834c00747f569614774908eb2dc35227 97 PRINTS PR00352 3Fe-4S ferredoxin signature 14 25 9.3E-7 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS10335 834c00747f569614774908eb2dc35227 97 PRINTS PR00352 3Fe-4S ferredoxin signature 68 80 9.3E-7 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS12085 ea5daf9a48ae1dd88e8aa4da191208cc 157 PANTHER PTHR21660:SF1 1 153 3.1E-88 T 23-04-2016 DC74_RS12085 ea5daf9a48ae1dd88e8aa4da191208cc 157 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 37 146 2.7E-26 T 23-04-2016 IPR003736 Phenylacetic acid degradation-related domain DC74_RS12085 ea5daf9a48ae1dd88e8aa4da191208cc 157 PANTHER PTHR21660 1 153 3.1E-88 T 23-04-2016 DC74_RS12085 ea5daf9a48ae1dd88e8aa4da191208cc 157 Pfam PF03061 Thioesterase superfamily 62 139 4.2E-16 T 23-04-2016 IPR006683 Thioesterase domain DC74_RS12085 ea5daf9a48ae1dd88e8aa4da191208cc 157 Gene3D G3DSA:3.10.129.10 24 149 1.5E-46 T 23-04-2016 IPR029069 HotDog domain DC74_RS12085 ea5daf9a48ae1dd88e8aa4da191208cc 157 SUPERFAMILY SSF54637 26 150 2.62E-28 T 23-04-2016 IPR029069 HotDog domain DC74_RS36745 85fca4dce769fe4f6d6450c60c9cc6e9 410 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 54 398 1.4E-93 T 23-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- DC74_RS36745 85fca4dce769fe4f6d6450c60c9cc6e9 410 PANTHER PTHR30521:SF4 37 410 1.2E-127 T 23-04-2016 DC74_RS36745 85fca4dce769fe4f6d6450c60c9cc6e9 410 PANTHER PTHR30521 37 410 1.2E-127 T 23-04-2016 DC74_RS36745 85fca4dce769fe4f6d6450c60c9cc6e9 410 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 2 409 3.9E-134 T 23-04-2016 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 KEGG: 00480+1.11.1.- DC74_RS36745 85fca4dce769fe4f6d6450c60c9cc6e9 410 SUPERFAMILY SSF54909 47 402 5.54E-95 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS36745 85fca4dce769fe4f6d6450c60c9cc6e9 410 Pfam PF04261 Dyp-type peroxidase family 54 398 1.1E-102 T 23-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- DC74_RS24750 8bc1776196f1e71356508800180f1249 255 Gene3D G3DSA:3.40.710.10 2 242 1.2E-32 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS24750 8bc1776196f1e71356508800180f1249 255 Pfam PF13354 Beta-lactamase enzyme family 16 213 2.9E-26 T 23-04-2016 DC74_RS24750 8bc1776196f1e71356508800180f1249 255 SUPERFAMILY SSF56601 3 232 2.44E-21 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS29905 9bbb7be93a79c1ca4d7429fd19d59914 135 PANTHER PTHR10173:SF18 3 135 5.5E-62 T 23-04-2016 DC74_RS29905 9bbb7be93a79c1ca4d7429fd19d59914 135 PANTHER PTHR10173 3 135 5.5E-62 T 23-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 DC74_RS29905 9bbb7be93a79c1ca4d7429fd19d59914 135 Gene3D G3DSA:2.170.150.20 2 134 1.9E-59 T 23-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 DC74_RS29905 9bbb7be93a79c1ca4d7429fd19d59914 135 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 134 9.5E-48 T 23-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 DC74_RS29905 9bbb7be93a79c1ca4d7429fd19d59914 135 Pfam PF01641 SelR domain 11 131 5.5E-52 T 23-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 DC74_RS29905 9bbb7be93a79c1ca4d7429fd19d59914 135 SUPERFAMILY SSF51316 6 134 6.28E-55 T 23-04-2016 IPR011057 Mss4-like DC74_RS22770 60638e934cee69ffb46950e568720d68 270 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 23-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 DC74_RS22770 60638e934cee69ffb46950e568720d68 270 Gene3D G3DSA:3.40.50.720 2 157 1.7E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS22770 60638e934cee69ffb46950e568720d68 270 PANTHER PTHR11645 1 264 1.8E-121 T 23-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 DC74_RS22770 60638e934cee69ffb46950e568720d68 270 PANTHER PTHR11645:SF0 1 264 1.8E-121 T 23-04-2016 DC74_RS22770 60638e934cee69ffb46950e568720d68 270 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 264 2.9E-81 T 23-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 DC74_RS22770 60638e934cee69ffb46950e568720d68 270 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 264 26.523 T 23-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 DC74_RS22770 60638e934cee69ffb46950e568720d68 270 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 97 2.9E-21 T 23-04-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal DC74_RS22770 60638e934cee69ffb46950e568720d68 270 SUPERFAMILY SSF48179 159 265 1.04E-35 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS22770 60638e934cee69ffb46950e568720d68 270 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 5.6E-38 T 23-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 DC74_RS22770 60638e934cee69ffb46950e568720d68 270 SUPERFAMILY SSF51735 4 158 1.51E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS22770 60638e934cee69ffb46950e568720d68 270 PIRSF PIRSF000193 2 267 1.5E-77 T 23-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 DC74_RS22770 60638e934cee69ffb46950e568720d68 270 Gene3D G3DSA:1.10.3730.10 159 264 4.0E-41 T 23-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 DC74_RS01890 0668354051b6d62c8198637aa42244ad 84 PANTHER PTHR24095 1 75 4.0E-12 T 23-04-2016 DC74_RS01890 0668354051b6d62c8198637aa42244ad 84 Gene3D G3DSA:1.10.1200.10 2 77 8.4E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01890 0668354051b6d62c8198637aa42244ad 84 Pfam PF00550 Phosphopantetheine attachment site 6 74 4.3E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01890 0668354051b6d62c8198637aa42244ad 84 SUPERFAMILY SSF47336 2 74 5.23E-16 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS13240 9e1941597078488a182a7ff57dd1c66f 278 PANTHER PTHR32243:SF18 3 278 2.4E-107 T 23-04-2016 DC74_RS13240 9e1941597078488a182a7ff57dd1c66f 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 271 6.3E-17 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS13240 9e1941597078488a182a7ff57dd1c66f 278 SUPERFAMILY SSF161098 8 278 6.15E-72 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS13240 9e1941597078488a182a7ff57dd1c66f 278 PANTHER PTHR32243 3 278 2.4E-107 T 23-04-2016 DC74_RS13240 9e1941597078488a182a7ff57dd1c66f 278 Gene3D G3DSA:1.10.3720.10 2 265 5.3E-69 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 SUPERFAMILY SSF81901 520 736 3.14E-22 T 23-04-2016 DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 SUPERFAMILY SSF81901 460 548 5.23E-11 T 23-04-2016 DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 Gene3D G3DSA:1.25.40.10 672 741 8.7E-32 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 Gene3D G3DSA:1.25.40.10 471 631 8.7E-32 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 PANTHER PTHR11102 684 740 7.6E-23 T 23-04-2016 DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 PANTHER PTHR11102 465 643 7.6E-23 T 23-04-2016 DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 Pfam PF08238 Sel1 repeat 712 732 0.028 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 Pfam PF08238 Sel1 repeat 685 700 120.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 Pfam PF08238 Sel1 repeat 491 504 0.52 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 Pfam PF08238 Sel1 repeat 612 627 13.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 SMART SM00671 506 537 350.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 SMART SM00671 474 505 110.0 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS40370 e80778bed7967ad4b0229fb0e9570722 744 SMART SM00671 701 732 0.0048 T 23-04-2016 IPR006597 Sel1-like repeat DC74_RS28045 092dcd1573c72e4f1bfdc41710af7661 566 SMART SM00248 275 304 0.12 T 23-04-2016 IPR002110 Ankyrin repeat GO:0005515 DC74_RS28045 092dcd1573c72e4f1bfdc41710af7661 566 SMART SM00248 308 339 2.7 T 23-04-2016 IPR002110 Ankyrin repeat GO:0005515 DC74_RS28045 092dcd1573c72e4f1bfdc41710af7661 566 Pfam PF12796 Ankyrin repeats (3 copies) 263 335 2.6E-8 T 23-04-2016 IPR020683 Ankyrin repeat-containing domain DC74_RS28045 092dcd1573c72e4f1bfdc41710af7661 566 PANTHER PTHR24158 278 350 2.2E-12 T 23-04-2016 DC74_RS28045 092dcd1573c72e4f1bfdc41710af7661 566 SUPERFAMILY SSF48403 252 352 5.24E-16 T 23-04-2016 IPR020683 Ankyrin repeat-containing domain DC74_RS28045 092dcd1573c72e4f1bfdc41710af7661 566 Gene3D G3DSA:1.25.40.20 254 351 5.6E-17 T 23-04-2016 IPR020683 Ankyrin repeat-containing domain DC74_RS31935 5435409090aa98b6acbbb043b64f584d 383 Pfam PF00155 Aminotransferase class I and II 41 315 8.4E-10 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS31935 5435409090aa98b6acbbb043b64f584d 383 SUPERFAMILY SSF53383 16 354 1.97E-34 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS31935 5435409090aa98b6acbbb043b64f584d 383 Gene3D G3DSA:3.40.640.10 41 209 2.0E-19 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS31935 5435409090aa98b6acbbb043b64f584d 383 PANTHER PTHR11751 11 335 6.6E-13 T 23-04-2016 DC74_RS25475 b19214274dedd50d11c9920373cf1fec 344 SUPERFAMILY SSF51430 17 333 1.96E-90 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS25475 b19214274dedd50d11c9920373cf1fec 344 Gene3D G3DSA:3.20.20.100 16 333 7.8E-86 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS25475 b19214274dedd50d11c9920373cf1fec 344 PANTHER PTHR11732:SF191 17 333 2.2E-168 T 23-04-2016 DC74_RS25475 b19214274dedd50d11c9920373cf1fec 344 PANTHER PTHR11732 17 333 2.2E-168 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS25475 b19214274dedd50d11c9920373cf1fec 344 Pfam PF00248 Aldo/keto reductase family 32 331 2.7E-66 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS07620 73fbfa87db07707346a71a268c166643 231 PANTHER PTHR26402:SF564 16 226 4.0E-82 T 23-04-2016 DC74_RS07620 73fbfa87db07707346a71a268c166643 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 207 3.1E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS07620 73fbfa87db07707346a71a268c166643 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 195 3.1E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS07620 73fbfa87db07707346a71a268c166643 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 179 3.1E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS07620 73fbfa87db07707346a71a268c166643 231 SUPERFAMILY SSF52172 16 139 4.13E-30 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS07620 73fbfa87db07707346a71a268c166643 231 Gene3D G3DSA:3.40.50.2300 12 133 5.0E-33 T 23-04-2016 DC74_RS07620 73fbfa87db07707346a71a268c166643 231 SUPERFAMILY SSF46894 152 225 1.19E-20 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS07620 73fbfa87db07707346a71a268c166643 231 Gene3D G3DSA:1.10.10.10 134 225 4.7E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07620 73fbfa87db07707346a71a268c166643 231 Pfam PF00072 Response regulator receiver domain 19 130 3.7E-27 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS07620 73fbfa87db07707346a71a268c166643 231 Pfam PF00196 Bacterial regulatory proteins, luxR family 164 219 3.5E-18 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS07620 73fbfa87db07707346a71a268c166643 231 SMART SM00421 162 219 2.9E-22 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS07620 73fbfa87db07707346a71a268c166643 231 ProSitePatterns PS00622 LuxR-type HTH domain signature. 179 206 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS07620 73fbfa87db07707346a71a268c166643 231 PANTHER PTHR26402 16 226 4.0E-82 T 23-04-2016 DC74_RS07620 73fbfa87db07707346a71a268c166643 231 SMART SM00448 16 130 2.1E-30 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS36480 d1848b91f9e9e5e801f436ac599e216d 297 Pfam PF04185 Phosphoesterase family 70 279 6.8E-32 T 23-04-2016 IPR007312 Phosphoesterase GO:0016788 DC74_RS36480 d1848b91f9e9e5e801f436ac599e216d 297 PANTHER PTHR31956 52 293 2.0E-66 T 23-04-2016 DC74_RS36480 d1848b91f9e9e5e801f436ac599e216d 297 PANTHER PTHR31956:SF13 52 293 2.0E-66 T 23-04-2016 DC74_RS36480 d1848b91f9e9e5e801f436ac599e216d 297 SUPERFAMILY SSF53649 50 284 2.18E-7 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS39720 ae5dbf75b7cdb13cf1569ef11bcf7c12 372 SUPERFAMILY SSF51679 1 356 1.31E-88 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS39720 ae5dbf75b7cdb13cf1569ef11bcf7c12 372 Pfam PF00296 Luciferase-like monooxygenase 6 329 4.9E-74 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS39720 ae5dbf75b7cdb13cf1569ef11bcf7c12 372 TIGRFAM TIGR04021 LLM_DMSO2_sfnG: dimethyl sulfone monooxygenase SfnG 5 358 2.2E-189 T 23-04-2016 IPR024014 Dimethyl sulphone monooxygenase SfnG DC74_RS39720 ae5dbf75b7cdb13cf1569ef11bcf7c12 372 PANTHER PTHR30011 1 356 2.4E-151 T 23-04-2016 DC74_RS39720 ae5dbf75b7cdb13cf1569ef11bcf7c12 372 PANTHER PTHR30011:SF13 1 356 2.4E-151 T 23-04-2016 DC74_RS39720 ae5dbf75b7cdb13cf1569ef11bcf7c12 372 Gene3D G3DSA:3.20.20.30 3 365 3.3E-96 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 76 5.2E-8 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 SMART SM01043 95 240 6.0E-40 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 PANTHER PTHR35807 1 331 2.4E-45 T 23-04-2016 DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 SUPERFAMILY SSF48452 90 251 6.07E-26 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 Gene3D G3DSA:1.25.40.10 709 993 4.7E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 PRINTS PR00364 Disease resistance protein signature 355 369 3.8E-5 T 23-04-2016 DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 PRINTS PR00364 Disease resistance protein signature 281 296 3.8E-5 T 23-04-2016 DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 PRINTS PR00364 Disease resistance protein signature 461 475 3.8E-5 T 23-04-2016 DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 Gene3D G3DSA:1.10.10.10 27 77 1.0E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 SMART SM00862 16 88 1.5E-9 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 Pfam PF03704 Bacterial transcriptional activator domain 95 240 1.7E-35 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 SUPERFAMILY SSF46894 3 88 2.13E-12 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 SUPERFAMILY SSF52540 251 528 8.45E-15 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20870 6f013e5a788ce72ba8492640671b1655 1047 SUPERFAMILY SSF48452 789 920 6.6E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS24915 b8c50f350b2ffc8a0f8d2d7e93408722 404 SUPERFAMILY SSF53187 317 402 3.97E-64 T 23-04-2016 DC74_RS24915 b8c50f350b2ffc8a0f8d2d7e93408722 404 SUPERFAMILY SSF53187 19 216 3.97E-64 T 23-04-2016 DC74_RS24915 b8c50f350b2ffc8a0f8d2d7e93408722 404 Gene3D G3DSA:3.40.630.10 317 403 7.4E-86 T 23-04-2016 DC74_RS24915 b8c50f350b2ffc8a0f8d2d7e93408722 404 Gene3D G3DSA:3.40.630.10 19 197 7.4E-86 T 23-04-2016 DC74_RS24915 b8c50f350b2ffc8a0f8d2d7e93408722 404 PIRSF PIRSF005962 16 404 3.3E-93 T 23-04-2016 IPR017439 Amidohydrolase GO:0016787 DC74_RS24915 b8c50f350b2ffc8a0f8d2d7e93408722 404 Pfam PF07687 Peptidase dimerisation domain 205 299 6.3E-5 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS24915 b8c50f350b2ffc8a0f8d2d7e93408722 404 Gene3D G3DSA:3.30.70.360 201 316 3.5E-28 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS24915 b8c50f350b2ffc8a0f8d2d7e93408722 404 Pfam PF01546 Peptidase family M20/M25/M40 89 401 8.8E-26 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS24915 b8c50f350b2ffc8a0f8d2d7e93408722 404 SUPERFAMILY SSF55031 202 315 1.03E-21 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS24915 b8c50f350b2ffc8a0f8d2d7e93408722 404 PANTHER PTHR11014:SF63 20 403 5.8E-128 T 23-04-2016 DC74_RS24915 b8c50f350b2ffc8a0f8d2d7e93408722 404 PANTHER PTHR11014 20 403 5.8E-128 T 23-04-2016 DC74_RS24915 b8c50f350b2ffc8a0f8d2d7e93408722 404 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 26 394 5.1E-101 T 23-04-2016 IPR017439 Amidohydrolase GO:0016787 DC74_RS01900 858bd01c721d415465935bbccbcf503f 326 SUPERFAMILY SSF53901 45 176 8.65E-14 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS01900 858bd01c721d415465935bbccbcf503f 326 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 188 1.2E-6 T 23-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS01900 858bd01c721d415465935bbccbcf503f 326 Gene3D G3DSA:3.40.47.10 50 176 2.9E-13 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS11455 a630e749fc7ee9a4fba61e02ba2b465c 156 Pfam PF03780 Asp23 family, cell envelope-related function 25 137 3.6E-30 T 23-04-2016 IPR005531 Alkaline shock protein Asp23 DC74_RS11455 a630e749fc7ee9a4fba61e02ba2b465c 156 PANTHER PTHR34297:SF1 3 145 2.0E-43 T 23-04-2016 DC74_RS11455 a630e749fc7ee9a4fba61e02ba2b465c 156 PANTHER PTHR34297 3 145 2.0E-43 T 23-04-2016 DC74_RS03985 a040f618e0132b29ef5fef9a1d53b969 234 PANTHER PTHR30055 6 136 2.9E-33 T 23-04-2016 DC74_RS03985 a040f618e0132b29ef5fef9a1d53b969 234 SUPERFAMILY SSF46689 13 76 8.03E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03985 a040f618e0132b29ef5fef9a1d53b969 234 Gene3D G3DSA:1.10.357.10 9 227 1.1E-34 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS03985 a040f618e0132b29ef5fef9a1d53b969 234 PANTHER PTHR30055:SF93 6 136 2.9E-33 T 23-04-2016 DC74_RS03985 a040f618e0132b29ef5fef9a1d53b969 234 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 90 200 4.0E-5 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS03985 a040f618e0132b29ef5fef9a1d53b969 234 SUPERFAMILY SSF48498 87 227 5.86E-9 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS03985 a040f618e0132b29ef5fef9a1d53b969 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 67 5.0E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 513 48.17 T 23-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 SUPERFAMILY SSF52540 100 382 1.09E-91 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 PANTHER PTHR15184:SF3 1 497 2.9E-275 T 23-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 Gene3D G3DSA:3.40.50.300 99 383 1.4E-106 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 2.4E-238 T 23-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 SUPERFAMILY SSF50615 27 98 6.54E-22 T 23-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 Gene3D G3DSA:1.20.150.20 384 512 2.5E-52 T 23-04-2016 DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 153 376 3.7E-66 T 23-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 507 4.0E-48 T 23-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 Gene3D G3DSA:2.40.30.20 5 97 4.6E-28 T 23-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 PANTHER PTHR15184 1 497 2.9E-275 T 23-04-2016 DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 23-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 SUPERFAMILY SSF47917 384 512 3.92E-47 T 23-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26935 e7b1b9337ad31937f395f4fc9abe242c 530 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 30 96 7.3E-15 T 23-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS23685 5f5c7c582d335d938b46b553250f5122 227 SUPERFAMILY SSF56784 10 204 1.43E-36 T 23-04-2016 IPR023214 HAD-like domain DC74_RS23685 5f5c7c582d335d938b46b553250f5122 227 PANTHER PTHR18901:SF14 10 226 1.9E-33 T 23-04-2016 DC74_RS23685 5f5c7c582d335d938b46b553250f5122 227 Gene3D G3DSA:1.10.150.240 22 74 4.1E-11 T 23-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 DC74_RS23685 5f5c7c582d335d938b46b553250f5122 227 Pfam PF12710 haloacid dehalogenase-like hydrolase 12 164 5.8E-14 T 23-04-2016 DC74_RS23685 5f5c7c582d335d938b46b553250f5122 227 Gene3D G3DSA:3.40.50.1000 75 205 5.2E-24 T 23-04-2016 IPR023214 HAD-like domain DC74_RS23685 5f5c7c582d335d938b46b553250f5122 227 PANTHER PTHR18901 10 226 1.9E-33 T 23-04-2016 DC74_RS15775 f6c60466a7f0e2cd7b5cd6504c74e112 293 Gene3D G3DSA:3.20.20.150 15 292 1.0E-66 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS15775 f6c60466a7f0e2cd7b5cd6504c74e112 293 PANTHER PTHR12110 5 290 1.7E-98 T 23-04-2016 DC74_RS15775 f6c60466a7f0e2cd7b5cd6504c74e112 293 PANTHER PTHR12110:SF27 5 290 1.7E-98 T 23-04-2016 DC74_RS15775 f6c60466a7f0e2cd7b5cd6504c74e112 293 Pfam PF01261 Xylose isomerase-like TIM barrel 31 238 1.7E-31 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS15775 f6c60466a7f0e2cd7b5cd6504c74e112 293 SUPERFAMILY SSF51658 12 285 2.62E-58 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 PIRSF PIRSF002811 2 628 1.3E-166 T 23-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 PANTHER PTHR30313 3 633 3.3E-137 T 23-04-2016 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 Hamap MF_00974 DNA primase [dnaG]. 4 622 26.205 T 23-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 Pfam PF13662 Toprim domain 262 332 6.4E-17 T 23-04-2016 IPR006171 Toprim domain DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 SUPERFAMILY SSF57783 4 102 1.48E-31 T 23-04-2016 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 Pfam PF01807 CHC2 zinc finger 7 101 8.1E-32 T 23-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 SMART SM00766 488 617 9.7E-12 T 23-04-2016 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 Gene3D G3DSA:3.90.980.10 117 241 4.7E-39 T 23-04-2016 IPR013264 DNA primase, catalytic core, N-terminal DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 Pfam PF10410 DnaB-helicase binding domain of primase 373 426 7.8E-15 T 23-04-2016 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 Gene3D G3DSA:3.40.1360.10 243 370 2.2E-41 T 23-04-2016 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 TIGRFAM TIGR01391 dnaG: DNA primase 5 420 8.2E-119 T 23-04-2016 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 Gene3D G3DSA:1.20.50.20 372 429 3.1E-9 T 23-04-2016 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 Pfam PF08278 DNA primase DnaG DnaB-binding 489 614 5.1E-16 T 23-04-2016 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 253 6.9E-37 T 23-04-2016 IPR013264 DNA primase, catalytic core, N-terminal DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 SMART SM00493 261 337 3.7E-15 T 23-04-2016 IPR006171 Toprim domain DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 SMART SM00400 37 91 6.5E-33 T 23-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 SUPERFAMILY SSF56731 117 428 1.67E-95 T 23-04-2016 DC74_RS14595 6c9f7e3a9c33709d4f1ef734974c430d 638 Gene3D G3DSA:3.90.580.10 3 102 1.7E-35 T 23-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 Pfam PF00672 HAMP domain 60 126 1.6E-15 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 PANTHER PTHR24423 5 23 7.4E-71 T 23-04-2016 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 PANTHER PTHR24423 72 220 7.4E-71 T 23-04-2016 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 PANTHER PTHR24423 238 370 7.4E-71 T 23-04-2016 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 SMART SM00304 78 130 3.6E-14 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 SUPERFAMILY SSF47384 114 195 1.71E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 Pfam PF00512 His Kinase A (phospho-acceptor) domain 132 195 6.1E-14 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 SMART SM00387 258 373 2.5E-37 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 259 370 1.2E-22 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 Gene3D G3DSA:3.30.565.10 251 373 8.6E-40 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 Gene3D G3DSA:3.30.565.10 182 214 8.6E-40 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 SUPERFAMILY SSF158472 80 126 3.4E-11 T 23-04-2016 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 SUPERFAMILY SSF55874 185 370 7.33E-36 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 315 325 1.5E-14 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 352 1.5E-14 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 370 1.5E-14 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 297 311 1.5E-14 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 SMART SM00388 131 195 1.8E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS26685 f5183f27b49a8c2dcdf89406e33b09b9 377 Gene3D G3DSA:1.10.287.130 121 181 6.4E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS32140 f7ff558d00c1114423d91c2e0637ff1e 335 SUPERFAMILY SSF53335 112 332 1.11E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS32140 f7ff558d00c1114423d91c2e0637ff1e 335 PANTHER PTHR11746:SF63 17 333 3.4E-49 T 23-04-2016 DC74_RS32140 f7ff558d00c1114423d91c2e0637ff1e 335 SUPERFAMILY SSF46785 14 89 3.7E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32140 f7ff558d00c1114423d91c2e0637ff1e 335 Pfam PF00891 O-methyltransferase 117 317 1.9E-29 T 23-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 DC74_RS32140 f7ff558d00c1114423d91c2e0637ff1e 335 PANTHER PTHR11746 17 333 3.4E-49 T 23-04-2016 DC74_RS32140 f7ff558d00c1114423d91c2e0637ff1e 335 PIRSF PIRSF005739 4 334 6.6E-31 T 23-04-2016 IPR016461 O-methyltransferase COMT-type GO:0008168 DC74_RS32140 f7ff558d00c1114423d91c2e0637ff1e 335 Gene3D G3DSA:1.10.10.10 6 97 1.4E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32140 f7ff558d00c1114423d91c2e0637ff1e 335 Gene3D G3DSA:3.40.50.150 110 333 1.0E-45 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS38495 bfc7e0cd777efba36bace46707b71163 185 Pfam PF13977 Bacterial transcriptional repressor 70 179 5.6E-15 T 23-04-2016 DC74_RS38495 bfc7e0cd777efba36bace46707b71163 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 44 8.9E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS38495 bfc7e0cd777efba36bace46707b71163 185 PANTHER PTHR30055 1 182 2.7E-15 T 23-04-2016 DC74_RS38495 bfc7e0cd777efba36bace46707b71163 185 Gene3D G3DSA:1.10.357.10 2 177 4.8E-25 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS38495 bfc7e0cd777efba36bace46707b71163 185 SUPERFAMILY SSF48498 69 177 1.78E-10 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS38495 bfc7e0cd777efba36bace46707b71163 185 SUPERFAMILY SSF46689 1 66 2.92E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS25345 a20d701900f1c69423653cfbb6d47591 403 Gene3D G3DSA:3.40.640.10 51 277 6.9E-69 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS25345 a20d701900f1c69423653cfbb6d47591 403 Gene3D G3DSA:3.90.1150.10 278 400 4.2E-39 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS25345 a20d701900f1c69423653cfbb6d47591 403 PANTHER PTHR11751:SF303 8 402 2.1E-185 T 23-04-2016 DC74_RS25345 a20d701900f1c69423653cfbb6d47591 403 SUPERFAMILY SSF53383 7 398 2.79E-96 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS25345 a20d701900f1c69423653cfbb6d47591 403 Pfam PF00155 Aminotransferase class I and II 34 393 2.5E-51 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS25345 a20d701900f1c69423653cfbb6d47591 403 PANTHER PTHR11751 8 402 2.1E-185 T 23-04-2016 DC74_RS15185 1fe5c43ebcaed45342dfa9defbc618f0 422 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 18 412 8.1E-152 T 23-04-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 DC74_RS15185 1fe5c43ebcaed45342dfa9defbc618f0 422 PIRSF PIRSF000151 3 422 4.3E-174 T 23-04-2016 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 DC74_RS15185 1fe5c43ebcaed45342dfa9defbc618f0 422 Gene3D G3DSA:3.40.309.10 232 380 2.2E-41 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS15185 1fe5c43ebcaed45342dfa9defbc618f0 422 SUPERFAMILY SSF53720 13 422 1.83E-118 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS15185 1fe5c43ebcaed45342dfa9defbc618f0 422 Pfam PF00171 Aldehyde dehydrogenase family 7 304 3.9E-22 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS15185 1fe5c43ebcaed45342dfa9defbc618f0 422 PANTHER PTHR11063:SF8 1 422 7.9E-184 T 23-04-2016 DC74_RS15185 1fe5c43ebcaed45342dfa9defbc618f0 422 Gene3D G3DSA:3.40.605.10 381 422 1.1E-103 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS15185 1fe5c43ebcaed45342dfa9defbc618f0 422 Gene3D G3DSA:3.40.605.10 6 229 1.1E-103 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS15185 1fe5c43ebcaed45342dfa9defbc618f0 422 PANTHER PTHR11063 1 422 7.9E-184 T 23-04-2016 DC74_RS15185 1fe5c43ebcaed45342dfa9defbc618f0 422 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 10 422 42.191 T 23-04-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 DC74_RS15185 1fe5c43ebcaed45342dfa9defbc618f0 422 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 329 350 - T 23-04-2016 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 DC74_RS35485 055d56c2c46713bec82cc61000c169b1 721 Pfam PF02687 FtsX-like permease family 192 300 3.1E-6 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS36025 9f7e78be817be75bd9b7458005dcd932 458 PANTHER PTHR11662 29 426 7.1E-101 T 23-04-2016 DC74_RS36025 9f7e78be817be75bd9b7458005dcd932 458 Gene3D G3DSA:1.20.1250.20 33 222 3.6E-48 T 23-04-2016 DC74_RS36025 9f7e78be817be75bd9b7458005dcd932 458 SUPERFAMILY SSF103473 26 433 1.11E-86 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS36025 9f7e78be817be75bd9b7458005dcd932 458 PANTHER PTHR11662:SF3 29 426 7.1E-101 T 23-04-2016 DC74_RS36025 9f7e78be817be75bd9b7458005dcd932 458 Pfam PF07690 Major Facilitator Superfamily 286 439 3.2E-9 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS36025 9f7e78be817be75bd9b7458005dcd932 458 Pfam PF07690 Major Facilitator Superfamily 39 279 6.6E-43 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS36025 9f7e78be817be75bd9b7458005dcd932 458 Gene3D G3DSA:1.20.1250.20 248 435 1.8E-22 T 23-04-2016 DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 SMART SM00421 186 243 3.2E-28 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 Pfam PF00196 Bacterial regulatory proteins, luxR family 188 243 4.7E-23 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 SUPERFAMILY SSF52172 35 167 4.84E-36 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 PANTHER PTHR26402:SF527 36 252 2.4E-111 T 23-04-2016 DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 Gene3D G3DSA:1.10.10.10 156 250 9.0E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 Pfam PF00072 Response regulator receiver domain 38 149 3.0E-27 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 203 8.1E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 203 219 8.1E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 219 231 8.1E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 SMART SM00448 36 149 4.2E-32 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 Gene3D G3DSA:3.40.50.2300 31 155 6.3E-38 T 23-04-2016 DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 PANTHER PTHR26402 36 252 2.4E-111 T 23-04-2016 DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 SUPERFAMILY SSF46894 172 249 3.74E-24 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS16850 1fa90ff3f374dff180a83c921be6ddd4 252 ProSitePatterns PS00622 LuxR-type HTH domain signature. 203 230 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01845 9164e485af174c8a849cd1761e034da8 123 PANTHER PTHR35908:SF1 1 123 3.1E-35 T 23-04-2016 DC74_RS01845 9164e485af174c8a849cd1761e034da8 123 PANTHER PTHR35908 1 123 3.1E-35 T 23-04-2016 DC74_RS01845 9164e485af174c8a849cd1761e034da8 123 SUPERFAMILY SSF54593 5 115 6.68E-13 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS01845 9164e485af174c8a849cd1761e034da8 123 Gene3D G3DSA:3.10.180.10 6 115 2.6E-10 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS39305 f0b9c52b16688cbaf9f98b78898d3a4f 366 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 28 135 3.8E-18 T 23-04-2016 IPR010033 HAD-superfamily phosphatase, subfamily IIIC DC74_RS39305 f0b9c52b16688cbaf9f98b78898d3a4f 366 Gene3D G3DSA:3.40.630.30 201 342 6.2E-8 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS39305 f0b9c52b16688cbaf9f98b78898d3a4f 366 SUPERFAMILY SSF56784 26 147 2.34E-17 T 23-04-2016 IPR023214 HAD-like domain DC74_RS39305 f0b9c52b16688cbaf9f98b78898d3a4f 366 TIGRFAM TIGR01686 FkbH: FkbH domain 27 334 2.6E-90 T 23-04-2016 IPR010037 FkbH domain DC74_RS39305 f0b9c52b16688cbaf9f98b78898d3a4f 366 SUPERFAMILY SSF55729 201 339 6.95E-7 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS39305 f0b9c52b16688cbaf9f98b78898d3a4f 366 Gene3D G3DSA:3.40.50.1000 27 158 2.1E-20 T 23-04-2016 IPR023214 HAD-like domain DC74_RS21525 85881377faafc42b63563c0eead958c1 275 PANTHER PTHR34293:SF1 3 274 7.8E-30 T 23-04-2016 DC74_RS21525 85881377faafc42b63563c0eead958c1 275 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 13 78 6.7E-17 T 23-04-2016 IPR002831 Transcription regulator TrmB, N-terminal DC74_RS21525 85881377faafc42b63563c0eead958c1 275 PANTHER PTHR34293 3 274 7.8E-30 T 23-04-2016 DC74_RS21525 85881377faafc42b63563c0eead958c1 275 SUPERFAMILY SSF46785 6 94 6.91E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21525 85881377faafc42b63563c0eead958c1 275 Gene3D G3DSA:1.10.10.10 8 96 2.7E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27745 4cdf30f01c01b3b6b45a398708c27274 368 ProSitePatterns PS00770 Aminotransferases class-IV signature. 238 273 - T 23-04-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS27745 4cdf30f01c01b3b6b45a398708c27274 368 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 48 366 2.6E-129 T 23-04-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 DC74_RS27745 4cdf30f01c01b3b6b45a398708c27274 368 PANTHER PTHR11825 6 366 2.2E-144 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS27745 4cdf30f01c01b3b6b45a398708c27274 368 PANTHER PTHR11825:SF2 6 366 2.2E-144 T 23-04-2016 DC74_RS27745 4cdf30f01c01b3b6b45a398708c27274 368 Gene3D G3DSA:3.30.470.10 21 179 3.2E-74 T 23-04-2016 DC74_RS27745 4cdf30f01c01b3b6b45a398708c27274 368 Gene3D G3DSA:3.20.10.10 180 354 2.5E-62 T 23-04-2016 DC74_RS27745 4cdf30f01c01b3b6b45a398708c27274 368 SUPERFAMILY SSF56752 12 365 5.62E-113 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS27745 4cdf30f01c01b3b6b45a398708c27274 368 PIRSF PIRSF006468 5 368 8.3E-130 T 23-04-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 DC74_RS27745 4cdf30f01c01b3b6b45a398708c27274 368 Pfam PF01063 Amino-transferase class IV 74 322 2.0E-28 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS02785 612d80888c043a676835d097d7636246 215 SMART SM00448 3 123 1.4E-13 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS02785 612d80888c043a676835d097d7636246 215 Gene3D G3DSA:1.10.10.10 154 214 1.7E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02785 612d80888c043a676835d097d7636246 215 SMART SM00421 149 211 4.1E-17 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02785 612d80888c043a676835d097d7636246 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 196 4.2E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02785 612d80888c043a676835d097d7636246 215 SUPERFAMILY SSF52172 3 174 1.11E-21 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS02785 612d80888c043a676835d097d7636246 215 Pfam PF00072 Response regulator receiver domain 5 102 2.2E-16 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS02785 612d80888c043a676835d097d7636246 215 Gene3D G3DSA:3.40.50.2300 3 153 2.4E-28 T 23-04-2016 DC74_RS02785 612d80888c043a676835d097d7636246 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 3.0E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02785 612d80888c043a676835d097d7636246 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 3.0E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02785 612d80888c043a676835d097d7636246 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 3.0E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02785 612d80888c043a676835d097d7636246 215 PANTHER PTHR26402 3 210 2.7E-77 T 23-04-2016 DC74_RS02785 612d80888c043a676835d097d7636246 215 PANTHER PTHR26402:SF582 3 210 2.7E-77 T 23-04-2016 DC74_RS37165 8be189963937622c6b737806e1c8191c 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 165 1.1E-20 T 23-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 DC74_RS37165 8be189963937622c6b737806e1c8191c 295 PANTHER PTHR22981 8 295 1.2E-33 T 23-04-2016 DC74_RS37165 8be189963937622c6b737806e1c8191c 295 SUPERFAMILY SSF48179 170 294 9.3E-5 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS37165 8be189963937622c6b737806e1c8191c 295 PANTHER PTHR22981:SF76 8 295 1.2E-33 T 23-04-2016 DC74_RS37165 8be189963937622c6b737806e1c8191c 295 Gene3D G3DSA:1.10.1040.10 186 293 5.0E-6 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS37165 8be189963937622c6b737806e1c8191c 295 PIRSF PIRSF000103 2 295 8.8E-39 T 23-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 DC74_RS37165 8be189963937622c6b737806e1c8191c 295 Gene3D G3DSA:3.40.50.720 7 167 1.4E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37165 8be189963937622c6b737806e1c8191c 295 SUPERFAMILY SSF51735 10 166 6.14E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36105 9853b13f553e0bc89217d8c64c4bbdcc 1379 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 824 1310 1.1E-121 T 23-04-2016 IPR013381 CRISPR-associated protein Cse1 DC74_RS36105 9853b13f553e0bc89217d8c64c4bbdcc 1379 SUPERFAMILY SSF52540 394 537 1.72E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36105 9853b13f553e0bc89217d8c64c4bbdcc 1379 SUPERFAMILY SSF52540 263 355 1.72E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36105 9853b13f553e0bc89217d8c64c4bbdcc 1379 SUPERFAMILY SSF52540 146 198 1.72E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36105 9853b13f553e0bc89217d8c64c4bbdcc 1379 Gene3D G3DSA:3.40.50.300 414 535 5.3E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36105 9853b13f553e0bc89217d8c64c4bbdcc 1379 Gene3D G3DSA:3.40.50.300 284 359 4.0E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36105 9853b13f553e0bc89217d8c64c4bbdcc 1379 Gene3D G3DSA:3.40.50.300 128 228 4.0E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36105 9853b13f553e0bc89217d8c64c4bbdcc 1379 Pfam PF00270 DEAD/DEAH box helicase 132 353 5.1E-6 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS36105 9853b13f553e0bc89217d8c64c4bbdcc 1379 SMART SM00487 126 381 4.0E-6 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS36105 9853b13f553e0bc89217d8c64c4bbdcc 1379 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 149 539 3.6E-50 T 23-04-2016 IPR006474 Helicase Cas3, CRISPR-associated, core DC74_RS36105 9853b13f553e0bc89217d8c64c4bbdcc 1379 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 824 1346 3.2E-64 T 23-04-2016 IPR013381 CRISPR-associated protein Cse1 DC74_RS01745 42a878d3b6d9e3dad47bb5497dc3f1f9 463 ProSitePatterns PS00571 Amidases signature. 147 178 - T 23-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS01745 42a878d3b6d9e3dad47bb5497dc3f1f9 463 Gene3D G3DSA:3.90.1300.10 4 458 2.3E-154 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS01745 42a878d3b6d9e3dad47bb5497dc3f1f9 463 PANTHER PTHR11895 5 461 1.8E-158 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS01745 42a878d3b6d9e3dad47bb5497dc3f1f9 463 Pfam PF01425 Amidase 24 444 7.1E-128 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS01745 42a878d3b6d9e3dad47bb5497dc3f1f9 463 SUPERFAMILY SSF75304 3 453 2.35E-145 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 Gene3D G3DSA:1.10.10.10 152 213 3.5E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 PANTHER PTHR26402:SF582 1 208 1.9E-88 T 23-04-2016 DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 SUPERFAMILY SSF52172 2 132 1.71E-20 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 SMART SM00448 1 120 1.3E-12 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 PANTHER PTHR26402 1 208 1.9E-88 T 23-04-2016 DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 Gene3D G3DSA:3.40.50.2300 2 151 1.3E-28 T 23-04-2016 DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 8.4E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 8.4E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 8.4E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 SMART SM00421 147 209 5.4E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 Pfam PF00072 Response regulator receiver domain 3 107 2.0E-14 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 194 8.7E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS21865 a7f3c2a94e41713be631fc6c6276b754 218 SUPERFAMILY SSF46894 136 194 1.87E-15 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS40555 5dacb6406ad93e189f6a1bfe9a967c10 77 PANTHER PTHR23501 1 74 1.3E-14 T 23-04-2016 DC74_RS40555 5dacb6406ad93e189f6a1bfe9a967c10 77 Pfam PF07690 Major Facilitator Superfamily 9 74 9.8E-10 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS40555 5dacb6406ad93e189f6a1bfe9a967c10 77 PANTHER PTHR23501:SF66 1 74 1.3E-14 T 23-04-2016 DC74_RS40555 5dacb6406ad93e189f6a1bfe9a967c10 77 Gene3D G3DSA:1.20.1250.20 2 74 1.3E-9 T 23-04-2016 DC74_RS40555 5dacb6406ad93e189f6a1bfe9a967c10 77 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 40 3.1E-5 T 23-04-2016 DC74_RS40555 5dacb6406ad93e189f6a1bfe9a967c10 77 PRINTS PR01036 Tetracycline resistance protein TetB signature 50 74 3.1E-5 T 23-04-2016 DC74_RS40555 5dacb6406ad93e189f6a1bfe9a967c10 77 SUPERFAMILY SSF103473 2 74 6.15E-13 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS11710 e77227f5e3d6854549b7208cb147c5f6 152 SUPERFAMILY SSF82649 2 141 2.88E-43 T 23-04-2016 DC74_RS11710 e77227f5e3d6854549b7208cb147c5f6 152 PANTHER PTHR10093 109 140 2.1E-39 T 23-04-2016 DC74_RS11710 e77227f5e3d6854549b7208cb147c5f6 152 PANTHER PTHR10093 3 90 2.1E-39 T 23-04-2016 DC74_RS11710 e77227f5e3d6854549b7208cb147c5f6 152 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 140 6.5E-48 T 23-04-2016 DC74_RS11710 e77227f5e3d6854549b7208cb147c5f6 152 Pfam PF01592 NifU-like N terminal domain 6 129 1.5E-26 T 23-04-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 DC74_RS11710 e77227f5e3d6854549b7208cb147c5f6 152 Gene3D G3DSA:3.90.1010.10 5 149 3.1E-45 T 23-04-2016 DC74_RS08020 72a0d8463634ca02fe8a68e616bffea4 304 PANTHER PTHR12715:SF4 1 296 6.9E-80 T 23-04-2016 DC74_RS08020 72a0d8463634ca02fe8a68e616bffea4 304 SUPERFAMILY SSF103481 179 288 4.97E-11 T 23-04-2016 DC74_RS08020 72a0d8463634ca02fe8a68e616bffea4 304 SUPERFAMILY SSF103481 30 126 4.58E-13 T 23-04-2016 DC74_RS08020 72a0d8463634ca02fe8a68e616bffea4 304 Pfam PF00892 EamA-like transporter family 1 125 2.4E-15 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS08020 72a0d8463634ca02fe8a68e616bffea4 304 Pfam PF00892 EamA-like transporter family 138 283 3.1E-14 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS08020 72a0d8463634ca02fe8a68e616bffea4 304 PANTHER PTHR12715 1 296 6.9E-80 T 23-04-2016 DC74_RS34580 8e7010dfde50a75882648b6ea0d10a1e 186 SUPERFAMILY SSF160904 5 177 8.76E-42 T 23-04-2016 DC74_RS34580 8e7010dfde50a75882648b6ea0d10a1e 186 PANTHER PTHR35525:SF3 7 185 1.1E-44 T 23-04-2016 DC74_RS34580 8e7010dfde50a75882648b6ea0d10a1e 186 Pfam PF11706 CGNR zinc finger 136 178 2.3E-16 T 23-04-2016 IPR021005 Zinc finger, CGNR DC74_RS34580 8e7010dfde50a75882648b6ea0d10a1e 186 Pfam PF07336 Putative stress-induced transcription regulator 10 131 5.3E-23 T 23-04-2016 IPR010852 Putative stress-induced transcription regulator DC74_RS34580 8e7010dfde50a75882648b6ea0d10a1e 186 Gene3D G3DSA:1.10.3300.10 5 179 1.4E-43 T 23-04-2016 IPR023286 ABATE domain DC74_RS34580 8e7010dfde50a75882648b6ea0d10a1e 186 PANTHER PTHR35525 7 185 1.1E-44 T 23-04-2016 DC74_RS15050 04c3b072b54c67cbe5885b12f82318b2 91 SUPERFAMILY SSF143212 3 84 7.19E-28 T 23-04-2016 DC74_RS15050 04c3b072b54c67cbe5885b12f82318b2 91 Pfam PF08962 Domain of unknown function (DUF1876) 7 85 8.8E-30 T 23-04-2016 IPR015057 Protein of unknown function DUF1876 DC74_RS15050 04c3b072b54c67cbe5885b12f82318b2 91 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 4 81 1.0E-31 T 23-04-2016 IPR015057 Protein of unknown function DUF1876 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 PANTHER PTHR10909:SF305 6 382 4.9E-173 T 23-04-2016 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 SUPERFAMILY SSF47203 227 378 5.48E-53 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 PANTHER PTHR10909 6 382 4.9E-173 T 23-04-2016 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 SUPERFAMILY SSF56645 5 241 1.44E-78 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 Gene3D G3DSA:1.10.540.10 5 118 7.3E-35 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 377 2.6E-47 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 7.5E-27 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 PIRSF PIRSF016578 2 374 1.9E-23 T 23-04-2016 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 216 2.1E-25 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 Gene3D G3DSA:2.40.110.10 122 218 3.4E-38 T 23-04-2016 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 Gene3D G3DSA:1.20.140.10 219 378 7.0E-62 T 23-04-2016 DC74_RS29410 6a069216252a013b386732fef13a7ce1 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS02540 b8fb055207caa6a07350d46af170ea97 136 Gene3D G3DSA:3.30.429.10 3 126 4.8E-35 T 23-04-2016 DC74_RS02540 b8fb055207caa6a07350d46af170ea97 136 PANTHER PTHR38460:SF1 2 129 6.9E-35 T 23-04-2016 DC74_RS02540 b8fb055207caa6a07350d46af170ea97 136 PANTHER PTHR38460 2 129 6.9E-35 T 23-04-2016 DC74_RS02540 b8fb055207caa6a07350d46af170ea97 136 Pfam PF14552 Tautomerase enzyme 37 119 2.3E-23 T 23-04-2016 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 DC74_RS02540 b8fb055207caa6a07350d46af170ea97 136 SUPERFAMILY SSF55331 3 127 4.42E-30 T 23-04-2016 IPR014347 Tautomerase/MIF superfamily DC74_RS18085 3838f886db8e5adfe36dd54bc8e60dcf 290 Pfam PF13714 Phosphoenolpyruvate phosphomutase 1 238 2.0E-63 T 23-04-2016 DC74_RS18085 3838f886db8e5adfe36dd54bc8e60dcf 290 PANTHER PTHR21631 1 242 5.9E-58 T 23-04-2016 DC74_RS18085 3838f886db8e5adfe36dd54bc8e60dcf 290 Gene3D G3DSA:3.20.20.60 5 219 1.8E-46 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS18085 3838f886db8e5adfe36dd54bc8e60dcf 290 PANTHER PTHR21631:SF18 1 242 5.9E-58 T 23-04-2016 DC74_RS18085 3838f886db8e5adfe36dd54bc8e60dcf 290 SUPERFAMILY SSF51621 5 244 4.97E-48 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS17835 efebe12775b68fd032fb8232f899c52f 160 Pfam PF01967 MoaC family 19 152 1.2E-51 T 23-04-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 DC74_RS17835 efebe12775b68fd032fb8232f899c52f 160 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 8 154 1.5E-61 T 23-04-2016 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 UniPathway: UPA00344 DC74_RS17835 efebe12775b68fd032fb8232f899c52f 160 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 6 160 36.038 T 23-04-2016 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type UniPathway: UPA00344 DC74_RS17835 efebe12775b68fd032fb8232f899c52f 160 Gene3D G3DSA:3.30.70.640 7 159 5.4E-64 T 23-04-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 DC74_RS17835 efebe12775b68fd032fb8232f899c52f 160 SUPERFAMILY SSF55040 15 157 1.96E-56 T 23-04-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 DC74_RS17835 efebe12775b68fd032fb8232f899c52f 160 PANTHER PTHR22960 8 160 3.5E-91 T 23-04-2016 DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 Gene3D G3DSA:3.40.50.300 39 81 1.8E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 PRINTS PR00364 Disease resistance protein signature 231 245 8.9E-6 T 23-04-2016 DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 PRINTS PR00364 Disease resistance protein signature 70 85 8.9E-6 T 23-04-2016 DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 PRINTS PR00364 Disease resistance protein signature 146 160 8.9E-6 T 23-04-2016 DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 Gene3D G3DSA:1.25.40.10 508 681 2.4E-21 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 SUPERFAMILY SSF52540 38 291 4.41E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 Pfam PF13424 Tetratricopeptide repeat 500 571 1.2E-9 T 23-04-2016 DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 PANTHER PTHR10098 371 389 6.3E-20 T 23-04-2016 DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 PANTHER PTHR10098 499 680 6.3E-20 T 23-04-2016 DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 SUPERFAMILY SSF48452 495 681 2.02E-18 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 Pfam PF00931 NB-ARC domain 66 248 1.0E-7 T 23-04-2016 IPR002182 NB-ARC GO:0043531 DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 SMART SM00382 67 218 6.9E-7 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 Gene3D G3DSA:3.40.50.300 82 169 3.8E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 SMART SM00028 501 534 170.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 SMART SM00028 541 574 19.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS11060 4e062809a481cafb5c3313f4005daf09 696 SMART SM00028 581 614 0.12 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS26525 f2f816b6f5b0982b589ebad60e56f0fa 243 PANTHER PTHR11019 159 233 6.0E-12 T 23-04-2016 DC74_RS26525 f2f816b6f5b0982b589ebad60e56f0fa 243 Pfam PF12833 Helix-turn-helix domain 164 241 2.7E-13 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS26525 f2f816b6f5b0982b589ebad60e56f0fa 243 PANTHER PTHR11019:SF126 159 233 6.0E-12 T 23-04-2016 DC74_RS26525 f2f816b6f5b0982b589ebad60e56f0fa 243 SMART SM00342 158 240 1.6E-7 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS35215 38ec66472b87f4fe7c0e4810133bace7 289 Gene3D G3DSA:3.40.50.620 2 137 7.9E-24 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS35215 38ec66472b87f4fe7c0e4810133bace7 289 Gene3D G3DSA:3.40.50.620 150 287 3.9E-20 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS35215 38ec66472b87f4fe7c0e4810133bace7 289 PANTHER PTHR31964 1 155 1.8E-22 T 23-04-2016 DC74_RS35215 38ec66472b87f4fe7c0e4810133bace7 289 Pfam PF00582 Universal stress protein family 156 287 1.9E-16 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS35215 38ec66472b87f4fe7c0e4810133bace7 289 Pfam PF00582 Universal stress protein family 3 137 3.5E-16 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS35215 38ec66472b87f4fe7c0e4810133bace7 289 PRINTS PR01438 Universal stress protein signature 115 137 2.2E-5 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS35215 38ec66472b87f4fe7c0e4810133bace7 289 PRINTS PR01438 Universal stress protein signature 2 20 2.2E-5 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS35215 38ec66472b87f4fe7c0e4810133bace7 289 PRINTS PR01438 Universal stress protein signature 97 109 2.2E-5 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS35215 38ec66472b87f4fe7c0e4810133bace7 289 SUPERFAMILY SSF52402 153 288 2.93E-18 T 23-04-2016 DC74_RS35215 38ec66472b87f4fe7c0e4810133bace7 289 PANTHER PTHR31964:SF42 1 155 1.8E-22 T 23-04-2016 DC74_RS35215 38ec66472b87f4fe7c0e4810133bace7 289 SUPERFAMILY SSF52402 5 138 2.85E-19 T 23-04-2016 DC74_RS31925 9846445635e60e6cd505d01b9a3b88e0 495 PANTHER PTHR14969:SF23 10 173 3.5E-73 T 23-04-2016 DC74_RS31925 9846445635e60e6cd505d01b9a3b88e0 495 SUPERFAMILY SSF48317 6 183 1.57E-35 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS31925 9846445635e60e6cd505d01b9a3b88e0 495 Gene3D G3DSA:3.40.50.10330 260 340 3.4E-6 T 23-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS31925 9846445635e60e6cd505d01b9a3b88e0 495 Pfam PF01569 PAP2 superfamily 66 176 7.3E-16 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS31925 9846445635e60e6cd505d01b9a3b88e0 495 SMART SM00014 63 172 4.9E-16 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS31925 9846445635e60e6cd505d01b9a3b88e0 495 SUPERFAMILY SSF111331 197 490 1.22E-46 T 23-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain DC74_RS31925 9846445635e60e6cd505d01b9a3b88e0 495 Pfam PF00781 Diacylglycerol kinase catalytic domain 200 322 1.6E-15 T 23-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 DC74_RS31925 9846445635e60e6cd505d01b9a3b88e0 495 Gene3D G3DSA:1.20.144.10 7 183 4.2E-30 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS31925 9846445635e60e6cd505d01b9a3b88e0 495 SMART SM00046 199 323 1.9E-7 T 23-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 DC74_RS31925 9846445635e60e6cd505d01b9a3b88e0 495 PANTHER PTHR14969 10 173 3.5E-73 T 23-04-2016 DC74_RS09710 949ec5207daf5d967e99bfd47151ae23 156 Gene3D G3DSA:3.30.530.20 14 154 2.4E-15 T 23-04-2016 IPR023393 START-like domain DC74_RS09710 949ec5207daf5d967e99bfd47151ae23 156 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 20 127 1.6E-10 T 23-04-2016 IPR019587 Polyketide cyclase/dehydrase DC74_RS09710 949ec5207daf5d967e99bfd47151ae23 156 SUPERFAMILY SSF55961 15 153 3.75E-16 T 23-04-2016 DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 SMART SM01134 76 237 1.2E-51 T 23-04-2016 DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 SUPERFAMILY SSF100950 78 218 7.95E-27 T 23-04-2016 DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 45 - T 23-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 SMART SM00420 12 63 1.5E-9 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 PANTHER PTHR30363:SF1 8 214 1.5E-52 T 23-04-2016 DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 PANTHER PTHR30363 8 214 1.5E-52 T 23-04-2016 DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 Gene3D G3DSA:3.40.50.1360 79 224 1.9E-15 T 23-04-2016 DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 SUPERFAMILY SSF46785 11 60 1.82E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 Pfam PF08220 DeoR-like helix-turn-helix domain 12 62 3.6E-12 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 29 43 7.5E-7 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 43 61 7.5E-7 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 Pfam PF00455 DeoR C terminal sensor domain 78 214 5.0E-40 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain DC74_RS36010 a3110faa4a12204dd20a82dc9869b909 284 Gene3D G3DSA:1.10.10.10 8 60 6.5E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19725 0fc838665804519e0581bb8cf6af78aa 234 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 229 40.655 T 23-04-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19725 0fc838665804519e0581bb8cf6af78aa 234 SMART SM01211 2 231 8.5E-121 T 23-04-2016 DC74_RS19725 0fc838665804519e0581bb8cf6af78aa 234 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 3 212 5.6E-38 T 23-04-2016 DC74_RS19725 0fc838665804519e0581bb8cf6af78aa 234 PANTHER PTHR10099 4 229 2.1E-103 T 23-04-2016 DC74_RS19725 0fc838665804519e0581bb8cf6af78aa 234 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 230 7.6E-83 T 23-04-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19725 0fc838665804519e0581bb8cf6af78aa 234 PIRSF PIRSF001586 1 234 1.1E-84 T 23-04-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19725 0fc838665804519e0581bb8cf6af78aa 234 SUPERFAMILY SSF52317 3 229 1.86E-68 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS19725 0fc838665804519e0581bb8cf6af78aa 234 Gene3D G3DSA:3.40.50.880 2 229 1.0E-39 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 PANTHER PTHR23115 2 615 2.1E-270 T 23-04-2016 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 22 196 7.6E-18 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 Pfam PF00679 Elongation factor G C-terminus 418 503 3.8E-21 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 SUPERFAMILY SSF52540 13 223 1.83E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 Gene3D G3DSA:2.40.30.10 214 309 1.5E-19 T 23-04-2016 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 SUPERFAMILY SSF54980 311 390 9.71E-20 T 23-04-2016 IPR009022 Elongation factor G, III-V domain DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 SUPERFAMILY SSF54980 417 513 9.59E-24 T 23-04-2016 IPR009022 Elongation factor G, III-V domain DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 Hamap MF_00071 Elongation factor 4 [lepA]. 1 617 281.402 T 23-04-2016 IPR006297 Elongation factor 4 GO:0005525 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 Gene3D G3DSA:3.30.70.240 420 508 1.3E-20 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 Pfam PF03144 Elongation factor Tu domain 2 225 295 1.2E-7 T 23-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 Pfam PF00009 Elongation factor Tu GTP binding domain 19 201 3.2E-50 T 23-04-2016 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 Gene3D G3DSA:3.40.50.300 16 213 1.6E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 TIGRFAM TIGR01393 lepA: elongation factor 4 19 615 1.3E-289 T 23-04-2016 IPR006297 Elongation factor 4 GO:0005525 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 SUPERFAMILY SSF50447 185 305 1.23E-24 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 SMART SM00838 417 501 7.6E-4 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 23-04-2016 IPR031157 Tr-type G domain, conserved site DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 Pfam PF06421 GTP-binding protein LepA C-terminus 508 613 4.6E-48 T 23-04-2016 IPR013842 GTP-binding protein LepA, C-terminal DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 PRINTS PR00315 GTP-binding elongation factor signature 64 72 4.2E-13 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 PRINTS PR00315 GTP-binding elongation factor signature 146 155 4.2E-13 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 PRINTS PR00315 GTP-binding elongation factor signature 94 104 4.2E-13 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 PRINTS PR00315 GTP-binding elongation factor signature 21 34 4.2E-13 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 PRINTS PR00315 GTP-binding elongation factor signature 110 121 4.2E-13 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 Gene3D G3DSA:3.30.70.870 311 388 2.0E-25 T 23-04-2016 DC74_RS15070 827f1200f10edc7b1c56a35a3a1f0a07 624 PANTHER PTHR23115:SF97 2 615 2.1E-270 T 23-04-2016 DC74_RS26465 4ba373e9676923b8681766681aeb0e51 222 SUPERFAMILY SSF48498 86 201 1.53E-25 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS26465 4ba373e9676923b8681766681aeb0e51 222 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS26465 4ba373e9676923b8681766681aeb0e51 222 SUPERFAMILY SSF46689 8 81 4.36E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS26465 4ba373e9676923b8681766681aeb0e51 222 PANTHER PTHR30055 3 201 1.1E-68 T 23-04-2016 DC74_RS26465 4ba373e9676923b8681766681aeb0e51 222 Gene3D G3DSA:1.10.357.10 74 202 1.3E-39 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS26465 4ba373e9676923b8681766681aeb0e51 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 3.3E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS26465 4ba373e9676923b8681766681aeb0e51 222 Gene3D G3DSA:1.10.10.60 7 70 4.4E-22 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS26465 4ba373e9676923b8681766681aeb0e51 222 PANTHER PTHR30055:SF79 3 201 1.1E-68 T 23-04-2016 DC74_RS18245 f5db668e02874bed8892dff3ed6652c7 285 SUPERFAMILY SSF51679 1 280 1.31E-50 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS18245 f5db668e02874bed8892dff3ed6652c7 285 Pfam PF00296 Luciferase-like monooxygenase 1 220 1.4E-46 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS18245 f5db668e02874bed8892dff3ed6652c7 285 PANTHER PTHR30011 18 218 1.4E-39 T 23-04-2016 DC74_RS18245 f5db668e02874bed8892dff3ed6652c7 285 Gene3D G3DSA:3.20.20.30 1 279 2.7E-55 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS18245 f5db668e02874bed8892dff3ed6652c7 285 PANTHER PTHR30011:SF5 18 218 1.4E-39 T 23-04-2016 DC74_RS18245 f5db668e02874bed8892dff3ed6652c7 285 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 21 255 9.6E-56 T 23-04-2016 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted DC74_RS00075 63ff1869428ae3023b81651d99b9609f 265 PANTHER PTHR33993 2 265 6.3E-25 T 23-04-2016 DC74_RS00075 63ff1869428ae3023b81651d99b9609f 265 SUPERFAMILY SSF54593 144 264 3.09E-20 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS00075 63ff1869428ae3023b81651d99b9609f 265 Gene3D G3DSA:3.10.180.10 147 263 9.1E-22 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS00075 63ff1869428ae3023b81651d99b9609f 265 Gene3D G3DSA:3.10.180.10 9 123 9.4E-22 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS00075 63ff1869428ae3023b81651d99b9609f 265 SUPERFAMILY SSF54593 9 129 9.13E-17 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS38090 a7cf8155652468e0ce324ddbf8d2d2b1 269 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.7E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS38090 a7cf8155652468e0ce324ddbf8d2d2b1 269 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.7E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS38090 a7cf8155652468e0ce324ddbf8d2d2b1 269 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.7E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS38090 a7cf8155652468e0ce324ddbf8d2d2b1 269 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 3.5E-22 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS38090 a7cf8155652468e0ce324ddbf8d2d2b1 269 PANTHER PTHR30346 1 265 8.4E-64 T 23-04-2016 DC74_RS38090 a7cf8155652468e0ce324ddbf8d2d2b1 269 PANTHER PTHR30346:SF7 1 265 8.4E-64 T 23-04-2016 DC74_RS38090 a7cf8155652468e0ce324ddbf8d2d2b1 269 SUPERFAMILY SSF46785 3 89 1.57E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38090 a7cf8155652468e0ce324ddbf8d2d2b1 269 Gene3D G3DSA:3.40.190.10 104 184 5.1E-16 T 23-04-2016 DC74_RS38090 a7cf8155652468e0ce324ddbf8d2d2b1 269 Pfam PF03466 LysR substrate binding domain 93 191 1.8E-18 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS38090 a7cf8155652468e0ce324ddbf8d2d2b1 269 Gene3D G3DSA:1.10.10.10 2 84 1.4E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38090 a7cf8155652468e0ce324ddbf8d2d2b1 269 SUPERFAMILY SSF53850 93 267 4.65E-23 T 23-04-2016 DC74_RS19795 d77b1994802f9531e7f8ad09377af761 227 Gene3D G3DSA:1.20.120.530 83 221 1.4E-14 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS19795 d77b1994802f9531e7f8ad09377af761 227 Pfam PF07729 FCD domain 107 214 2.1E-11 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS19795 d77b1994802f9531e7f8ad09377af761 227 SUPERFAMILY SSF46785 12 83 5.89E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19795 d77b1994802f9531e7f8ad09377af761 227 Gene3D G3DSA:1.10.10.10 6 79 2.3E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19795 d77b1994802f9531e7f8ad09377af761 227 SUPERFAMILY SSF48008 85 222 6.02E-13 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS19795 d77b1994802f9531e7f8ad09377af761 227 PANTHER PTHR11751 15 109 1.1E-18 T 23-04-2016 DC74_RS19795 d77b1994802f9531e7f8ad09377af761 227 SMART SM00345 21 79 3.2E-14 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS19795 d77b1994802f9531e7f8ad09377af761 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 79 1.9E-17 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 Gene3D G3DSA:2.60.40.10 572 651 2.6E-11 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 SUPERFAMILY SSF49313 569 652 5.65E-13 T 23-04-2016 IPR015919 Cadherin-like GO:0005509|GO:0016020 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 PANTHER PTHR33794 61 579 3.4E-196 T 23-04-2016 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 235 380 5.2E-47 T 23-04-2016 IPR013856 Peptidase M4 domain GO:0004222 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 Gene3D G3DSA:2.60.120.260 690 768 5.0E-15 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 Gene3D G3DSA:3.10.170.10 234 385 1.2E-43 T 23-04-2016 IPR013856 Peptidase M4 domain GO:0004222 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 Gene3D G3DSA:1.10.390.10 386 558 7.0E-53 T 23-04-2016 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 SMART SM00736 567 656 0.0088 T 23-04-2016 IPR006644 Dystroglycan-type cadherin-like GO:0016020 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 SUPERFAMILY SSF55486 234 559 7.69E-79 T 23-04-2016 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 SUPERFAMILY SSF49785 657 768 4.25E-22 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 94 140 8.9E-17 T 23-04-2016 IPR011096 FTP domain DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 PANTHER PTHR33794:SF2 61 579 3.4E-196 T 23-04-2016 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 Pfam PF05345 Putative Ig domain 598 637 2.1E-11 T 23-04-2016 IPR008009 Putative Ig DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 Pfam PF01483 Proprotein convertase P-domain 690 768 4.2E-18 T 23-04-2016 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 384 558 8.9E-53 T 23-04-2016 IPR001570 Peptidase M4, C-terminal GO:0004222 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 372 388 4.0E-18 T 23-04-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 336 356 4.0E-18 T 23-04-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 393 404 4.0E-18 T 23-04-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 DC74_RS27340 f269b7d4cc0f1ef6996f4c47477f7a3b 768 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 460 476 4.0E-18 T 23-04-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 DC74_RS00290 54c0899d345a9701d08df8255533860b 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.0E-8 T 23-04-2016 DC74_RS00290 54c0899d345a9701d08df8255533860b 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 3.0E-8 T 23-04-2016 DC74_RS00290 54c0899d345a9701d08df8255533860b 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 3.0E-8 T 23-04-2016 DC74_RS00290 54c0899d345a9701d08df8255533860b 411 PANTHER PTHR13789 2 363 1.5E-104 T 23-04-2016 DC74_RS00290 54c0899d345a9701d08df8255533860b 411 Gene3D G3DSA:3.50.50.60 2 170 2.1E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS00290 54c0899d345a9701d08df8255533860b 411 Gene3D G3DSA:3.50.50.60 266 339 2.1E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS00290 54c0899d345a9701d08df8255533860b 411 Pfam PF01494 FAD binding domain 2 160 5.1E-10 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS00290 54c0899d345a9701d08df8255533860b 411 SUPERFAMILY SSF51905 265 365 6.08E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS00290 54c0899d345a9701d08df8255533860b 411 SUPERFAMILY SSF51905 3 165 6.08E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS00290 54c0899d345a9701d08df8255533860b 411 PANTHER PTHR13789:SF246 2 363 1.5E-104 T 23-04-2016 DC74_RS36845 0fdc9579166c5119a00d0ee5a4e2d2bd 201 Pfam PF00857 Isochorismatase family 23 195 5.6E-26 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS36845 0fdc9579166c5119a00d0ee5a4e2d2bd 201 PANTHER PTHR11080:SF17 1 198 6.7E-61 T 23-04-2016 DC74_RS36845 0fdc9579166c5119a00d0ee5a4e2d2bd 201 Gene3D G3DSA:3.40.50.850 10 199 1.4E-36 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS36845 0fdc9579166c5119a00d0ee5a4e2d2bd 201 PANTHER PTHR11080 1 198 6.7E-61 T 23-04-2016 DC74_RS36845 0fdc9579166c5119a00d0ee5a4e2d2bd 201 SUPERFAMILY SSF52499 9 198 4.97E-37 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS15085 a7afce5290505f93a83f2cda85a05b31 327 PANTHER PTHR34388 1 327 2.0E-70 T 23-04-2016 DC74_RS15085 a7afce5290505f93a83f2cda85a05b31 327 Pfam PF06144 DNA polymerase III, delta subunit 17 179 4.0E-10 T 23-04-2016 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 DC74_RS15085 a7afce5290505f93a83f2cda85a05b31 327 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 11 320 1.0E-31 T 23-04-2016 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 DC74_RS15085 a7afce5290505f93a83f2cda85a05b31 327 Gene3D G3DSA:1.10.8.60 137 212 8.7E-7 T 23-04-2016 DC74_RS15085 a7afce5290505f93a83f2cda85a05b31 327 SUPERFAMILY SSF48019 203 322 1.87E-16 T 23-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 DC74_RS15085 a7afce5290505f93a83f2cda85a05b31 327 Gene3D G3DSA:1.20.272.20 213 323 2.3E-4 T 23-04-2016 DC74_RS15085 a7afce5290505f93a83f2cda85a05b31 327 Gene3D G3DSA:3.40.50.300 9 105 6.2E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23885 c0e09c7b4caf6d405bb09ca4e60f74a4 250 PANTHER PTHR11941:SF86 1 248 5.8E-86 T 23-04-2016 DC74_RS23885 c0e09c7b4caf6d405bb09ca4e60f74a4 250 SUPERFAMILY SSF52096 4 248 3.78E-61 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS23885 c0e09c7b4caf6d405bb09ca4e60f74a4 250 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 248 1.0E-44 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS23885 c0e09c7b4caf6d405bb09ca4e60f74a4 250 Gene3D G3DSA:1.10.12.10 194 248 3.5E-13 T 23-04-2016 IPR014748 Crontonase, C-terminal DC74_RS23885 c0e09c7b4caf6d405bb09ca4e60f74a4 250 Gene3D G3DSA:3.90.226.10 4 178 4.9E-46 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS23885 c0e09c7b4caf6d405bb09ca4e60f74a4 250 PANTHER PTHR11941 1 248 5.8E-86 T 23-04-2016 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 Gene3D G3DSA:3.50.50.60 111 195 5.3E-53 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 Gene3D G3DSA:3.50.50.60 278 355 5.3E-53 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 Gene3D G3DSA:3.50.50.60 9 74 5.3E-53 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 SUPERFAMILY SSF51905 277 361 8.64E-56 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 SUPERFAMILY SSF51905 9 190 8.64E-56 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 Pfam PF01494 FAD binding domain 9 355 1.9E-88 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 PANTHER PTHR13789:SF90 7 361 1.7E-61 T 23-04-2016 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 PANTHER PTHR13789 7 361 1.7E-61 T 23-04-2016 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 3.9E-38 T 23-04-2016 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 3.9E-38 T 23-04-2016 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 321 3.9E-38 T 23-04-2016 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 341 3.9E-38 T 23-04-2016 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 169 184 3.9E-38 T 23-04-2016 DC74_RS35925 1d10554ef444bc3f67a7def7a7f7e88f 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 357 3.9E-38 T 23-04-2016 DC74_RS34055 c0312d880949b277aba3fda540a0f849 222 Gene3D G3DSA:3.40.50.10420 41 212 2.4E-54 T 23-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain DC74_RS34055 c0312d880949b277aba3fda540a0f849 222 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 103 212 1.3E-19 T 23-04-2016 IPR003741 LUD domain DC74_RS34055 c0312d880949b277aba3fda540a0f849 222 SUPERFAMILY SSF100950 41 212 2.76E-37 T 23-04-2016 DC74_RS34055 c0312d880949b277aba3fda540a0f849 222 PANTHER PTHR32479:SF11 3 212 1.3E-41 T 23-04-2016 DC74_RS34055 c0312d880949b277aba3fda540a0f849 222 PANTHER PTHR32479 3 212 1.3E-41 T 23-04-2016 DC74_RS28355 e06f24594ca3f1ba57d281c64f3fc512 449 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 31 445 2.2E-178 T 23-04-2016 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 DC74_RS28355 e06f24594ca3f1ba57d281c64f3fc512 449 Pfam PF00202 Aminotransferase class-III 42 445 4.9E-120 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS28355 e06f24594ca3f1ba57d281c64f3fc512 449 Gene3D G3DSA:3.40.640.10 82 329 1.4E-78 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS28355 e06f24594ca3f1ba57d281c64f3fc512 449 PANTHER PTHR11986:SF17 8 446 3.4E-199 T 23-04-2016 DC74_RS28355 e06f24594ca3f1ba57d281c64f3fc512 449 PANTHER PTHR11986 8 446 3.4E-199 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS28355 e06f24594ca3f1ba57d281c64f3fc512 449 Gene3D G3DSA:3.90.1150.10 330 447 4.7E-40 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS28355 e06f24594ca3f1ba57d281c64f3fc512 449 SUPERFAMILY SSF53383 40 446 6.56E-124 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS28355 e06f24594ca3f1ba57d281c64f3fc512 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 262 299 - T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS19310 55856a148240c4ff38a25b34c0236aa2 204 PANTHER PTHR10681 59 203 1.3E-40 T 23-04-2016 DC74_RS19310 55856a148240c4ff38a25b34c0236aa2 204 Gene3D G3DSA:3.40.30.10 15 203 3.1E-47 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS19310 55856a148240c4ff38a25b34c0236aa2 204 SUPERFAMILY SSF52833 58 203 5.68E-37 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS19310 55856a148240c4ff38a25b34c0236aa2 204 Pfam PF00578 AhpC/TSA family 62 182 9.2E-24 T 23-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS19310 55856a148240c4ff38a25b34c0236aa2 204 PANTHER PTHR10681:SF125 59 203 1.3E-40 T 23-04-2016 DC74_RS04700 41f078543d8668f8465a0d9c352034c2 188 PANTHER PTHR30055:SF75 1 176 1.2E-27 T 23-04-2016 DC74_RS04700 41f078543d8668f8465a0d9c352034c2 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS04700 41f078543d8668f8465a0d9c352034c2 188 Gene3D G3DSA:1.10.10.60 10 53 9.6E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04700 41f078543d8668f8465a0d9c352034c2 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.8E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS04700 41f078543d8668f8465a0d9c352034c2 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 4.8E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS04700 41f078543d8668f8465a0d9c352034c2 188 PANTHER PTHR30055 1 176 1.2E-27 T 23-04-2016 DC74_RS04700 41f078543d8668f8465a0d9c352034c2 188 Gene3D G3DSA:1.10.357.10 54 183 1.6E-15 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS04700 41f078543d8668f8465a0d9c352034c2 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 55 1.2E-14 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS04700 41f078543d8668f8465a0d9c352034c2 188 SUPERFAMILY SSF46689 9 69 5.64E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS20525 f061eb0dbfad86972822480f2200c662 216 Pfam PF02525 Flavodoxin-like fold 3 163 5.7E-33 T 23-04-2016 IPR003680 Flavodoxin-like fold DC74_RS20525 f061eb0dbfad86972822480f2200c662 216 PANTHER PTHR10204:SF37 1 214 1.1E-88 T 23-04-2016 DC74_RS20525 f061eb0dbfad86972822480f2200c662 216 SUPERFAMILY SSF52218 1 210 4.04E-39 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS20525 f061eb0dbfad86972822480f2200c662 216 Gene3D G3DSA:3.40.50.360 1 212 1.9E-57 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS20525 f061eb0dbfad86972822480f2200c662 216 PANTHER PTHR10204 1 214 1.1E-88 T 23-04-2016 DC74_RS20525 f061eb0dbfad86972822480f2200c662 216 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 215 26.545 T 23-04-2016 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 DC74_RS26985 ba0f097aee7c0d0e8b78059f30a51932 95 Pfam PF00550 Phosphopantetheine attachment site 1 59 1.2E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS26985 ba0f097aee7c0d0e8b78059f30a51932 95 SMART SM00823 Phosphopantetheine attachment site 1 63 4.0E-5 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS26985 ba0f097aee7c0d0e8b78059f30a51932 95 Gene3D G3DSA:1.10.1200.10 7 61 1.4E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS26985 ba0f097aee7c0d0e8b78059f30a51932 95 SUPERFAMILY SSF47336 8 66 1.57E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS23220 94e126a732d865378d4167f6047b0628 487 SUPERFAMILY SSF47384 245 330 2.35E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 Pfam PF00672 HAMP domain 188 257 8.0E-15 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 SMART SM00387 377 483 1.4E-33 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23220 94e126a732d865378d4167f6047b0628 487 Gene3D G3DSA:1.10.287.130 253 329 7.3E-12 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 PANTHER PTHR24423 202 487 3.1E-59 T 23-04-2016 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 PANTHER PTHR24423 21 28 3.1E-59 T 23-04-2016 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 480 6.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 438 6.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 461 6.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 424 6.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 SMART SM00304 208 261 5.6E-12 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 Pfam PF00512 His Kinase A (phospho-acceptor) domain 263 329 1.3E-9 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 Gene3D G3DSA:3.30.565.10 341 483 1.9E-34 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23220 94e126a732d865378d4167f6047b0628 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 380 480 4.0E-22 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23220 94e126a732d865378d4167f6047b0628 487 SUPERFAMILY SSF158472 209 257 3.01E-7 T 23-04-2016 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 SMART SM00388 262 333 9.7E-8 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS23220 94e126a732d865378d4167f6047b0628 487 SUPERFAMILY SSF55874 340 483 1.19E-34 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS09735 7350b100053a17105a02624895be4d72 183 Gene3D G3DSA:3.40.30.10 19 172 3.8E-31 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS09735 7350b100053a17105a02624895be4d72 183 SUPERFAMILY SSF52833 18 168 1.49E-27 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS09735 7350b100053a17105a02624895be4d72 183 Pfam PF13462 Thioredoxin 19 168 1.4E-20 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS09735 7350b100053a17105a02624895be4d72 183 PANTHER PTHR13887 10 173 3.9E-70 T 23-04-2016 DC74_RS09735 7350b100053a17105a02624895be4d72 183 PANTHER PTHR13887:SF24 10 173 3.9E-70 T 23-04-2016 DC74_RS12980 49bb49301cda5e75d1b87b97db3dcd00 305 PANTHER PTHR11935 67 294 2.6E-30 T 23-04-2016 DC74_RS12980 49bb49301cda5e75d1b87b97db3dcd00 305 SUPERFAMILY SSF56281 89 279 5.78E-38 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS12980 49bb49301cda5e75d1b87b97db3dcd00 305 Gene3D G3DSA:3.60.15.10 87 284 3.0E-51 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS12980 49bb49301cda5e75d1b87b97db3dcd00 305 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 22 74 4.7E-8 T 23-04-2016 DC74_RS12980 49bb49301cda5e75d1b87b97db3dcd00 305 Pfam PF00753 Metallo-beta-lactamase superfamily 110 261 1.1E-4 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS12980 49bb49301cda5e75d1b87b97db3dcd00 305 PANTHER PTHR11935:SF104 67 294 2.6E-30 T 23-04-2016 DC74_RS12980 49bb49301cda5e75d1b87b97db3dcd00 305 SMART SM00849 108 268 6.6E-16 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS12810 aa5b98006f8058b56432767dd4822f4f 362 PANTHER PTHR21666 27 47 5.5E-34 T 23-04-2016 DC74_RS12810 aa5b98006f8058b56432767dd4822f4f 362 PANTHER PTHR21666 254 353 5.5E-34 T 23-04-2016 DC74_RS12810 aa5b98006f8058b56432767dd4822f4f 362 SUPERFAMILY SSF54001 246 352 9.32E-38 T 23-04-2016 DC74_RS12810 aa5b98006f8058b56432767dd4822f4f 362 Gene3D G3DSA:3.90.1720.10 247 352 4.5E-41 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS12810 aa5b98006f8058b56432767dd4822f4f 362 Pfam PF00877 NlpC/P60 family 263 350 3.4E-26 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS26690 c5f1bfee4b265af19605b914452f645e 246 SMART SM00862 170 241 1.7E-25 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS26690 c5f1bfee4b265af19605b914452f645e 246 SMART SM00448 20 130 7.2E-42 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS26690 c5f1bfee4b265af19605b914452f645e 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 170 241 1.1E-23 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS26690 c5f1bfee4b265af19605b914452f645e 246 Gene3D G3DSA:3.40.50.2300 17 138 9.6E-40 T 23-04-2016 DC74_RS26690 c5f1bfee4b265af19605b914452f645e 246 Pfam PF00072 Response regulator receiver domain 22 130 1.2E-27 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS26690 c5f1bfee4b265af19605b914452f645e 246 PANTHER PTHR26402:SF292 20 246 1.5E-98 T 23-04-2016 DC74_RS26690 c5f1bfee4b265af19605b914452f645e 246 SUPERFAMILY SSF52172 16 139 1.57E-41 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS26690 c5f1bfee4b265af19605b914452f645e 246 PANTHER PTHR26402 20 246 1.5E-98 T 23-04-2016 DC74_RS26690 c5f1bfee4b265af19605b914452f645e 246 Gene3D G3DSA:1.10.10.10 148 243 8.9E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26690 c5f1bfee4b265af19605b914452f645e 246 SUPERFAMILY SSF46894 147 242 5.39E-27 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS26320 a76bc48750bf68687a7521efc98debf7 132 PANTHER PTHR11911 1 119 1.5E-34 T 23-04-2016 DC74_RS26320 a76bc48750bf68687a7521efc98debf7 132 SUPERFAMILY SSF54631 1 123 4.55E-30 T 23-04-2016 DC74_RS26320 a76bc48750bf68687a7521efc98debf7 132 PANTHER PTHR11911:SF107 1 119 1.5E-34 T 23-04-2016 DC74_RS26320 a76bc48750bf68687a7521efc98debf7 132 SMART SM00116 10 58 0.0021 T 23-04-2016 IPR000644 CBS domain DC74_RS26320 a76bc48750bf68687a7521efc98debf7 132 SMART SM00116 75 122 8.5E-8 T 23-04-2016 IPR000644 CBS domain DC74_RS26320 a76bc48750bf68687a7521efc98debf7 132 Gene3D G3DSA:3.10.580.10 1 122 8.8E-32 T 23-04-2016 DC74_RS26320 a76bc48750bf68687a7521efc98debf7 132 Pfam PF00571 CBS domain 3 57 4.7E-9 T 23-04-2016 IPR000644 CBS domain DC74_RS26320 a76bc48750bf68687a7521efc98debf7 132 Pfam PF00571 CBS domain 73 120 1.4E-11 T 23-04-2016 IPR000644 CBS domain DC74_RS17280 9f2d22ab153d8a54b0fc33b1e965d744 330 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 69 248 6.4E-22 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS17280 9f2d22ab153d8a54b0fc33b1e965d744 330 Gene3D G3DSA:3.40.50.1110 66 260 3.3E-24 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS17280 9f2d22ab153d8a54b0fc33b1e965d744 330 PANTHER PTHR30383 64 275 9.4E-17 T 23-04-2016 DC74_RS17280 9f2d22ab153d8a54b0fc33b1e965d744 330 SUPERFAMILY SSF52266 64 262 5.8E-30 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS31035 e2d0317d0540bfd54eb769f7b0e555c7 251 Pfam PF13977 Bacterial transcriptional repressor 128 240 1.4E-12 T 23-04-2016 DC74_RS31035 e2d0317d0540bfd54eb769f7b0e555c7 251 Pfam PF00440 Bacterial regulatory proteins, tetR family 67 102 4.9E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS31035 e2d0317d0540bfd54eb769f7b0e555c7 251 PANTHER PTHR30055 36 214 6.0E-21 T 23-04-2016 DC74_RS31035 e2d0317d0540bfd54eb769f7b0e555c7 251 SUPERFAMILY SSF46689 53 115 1.28E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS31035 e2d0317d0540bfd54eb769f7b0e555c7 251 SUPERFAMILY SSF48498 126 242 1.48E-13 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS31035 e2d0317d0540bfd54eb769f7b0e555c7 251 Gene3D G3DSA:1.10.357.10 53 228 2.4E-33 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS06980 9137339eba2484d99ad0364bcc846f8e 318 Gene3D G3DSA:1.10.10.60 213 265 3.2E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06980 9137339eba2484d99ad0364bcc846f8e 318 Gene3D G3DSA:1.10.10.60 266 316 8.0E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06980 9137339eba2484d99ad0364bcc846f8e 318 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 265 307 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS06980 9137339eba2484d99ad0364bcc846f8e 318 SUPERFAMILY SSF46689 264 315 8.24E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06980 9137339eba2484d99ad0364bcc846f8e 318 Pfam PF01965 DJ-1/PfpI family 6 173 3.1E-19 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS06980 9137339eba2484d99ad0364bcc846f8e 318 SUPERFAMILY SSF46689 214 261 2.33E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06980 9137339eba2484d99ad0364bcc846f8e 318 PANTHER PTHR11019 1 316 1.2E-112 T 23-04-2016 DC74_RS06980 9137339eba2484d99ad0364bcc846f8e 318 Pfam PF12833 Helix-turn-helix domain 234 312 1.6E-21 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS06980 9137339eba2484d99ad0364bcc846f8e 318 SUPERFAMILY SSF52317 5 194 2.38E-47 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS06980 9137339eba2484d99ad0364bcc846f8e 318 SMART SM00342 228 311 2.0E-28 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS06980 9137339eba2484d99ad0364bcc846f8e 318 PANTHER PTHR11019:SF68 1 316 1.2E-112 T 23-04-2016 DC74_RS06980 9137339eba2484d99ad0364bcc846f8e 318 Gene3D G3DSA:3.40.50.880 5 194 1.4E-48 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 203 223 2.6E-47 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 244 267 2.6E-47 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 224 241 2.6E-47 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 268 282 2.6E-47 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 145 159 2.6E-47 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 PIRSF PIRSF001134 14 303 1.5E-96 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 Pfam PF00089 Trypsin 119 295 3.4E-10 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 Gene3D G3DSA:2.40.10.10 119 201 2.8E-30 T 23-04-2016 DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 SUPERFAMILY SSF50494 126 296 3.42E-37 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 Gene3D G3DSA:3.30.300.50 49 114 2.0E-9 T 23-04-2016 DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 147 152 - T 23-04-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 Gene3D G3DSA:2.40.10.10 202 290 1.5E-30 T 23-04-2016 DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 Pfam PF02983 Alpha-lytic protease prodomain 48 102 6.3E-11 T 23-04-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 DC74_RS10865 74b02b4d87814fb5ffc77046d751050c 303 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 253 264 - T 23-04-2016 IPR033116 Serine proteases, trypsin family, serine active site DC74_RS16410 0ac9ecaead77e4e22c009828b9777b74 198 SUPERFAMILY SSF52499 2 190 1.09E-47 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS16410 0ac9ecaead77e4e22c009828b9777b74 198 Pfam PF00857 Isochorismatase family 4 190 5.1E-33 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS16410 0ac9ecaead77e4e22c009828b9777b74 198 PANTHER PTHR11080 1 189 5.8E-46 T 23-04-2016 DC74_RS16410 0ac9ecaead77e4e22c009828b9777b74 198 Gene3D G3DSA:3.40.50.850 1 190 1.4E-59 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS16410 0ac9ecaead77e4e22c009828b9777b74 198 PANTHER PTHR11080:SF2 1 189 5.8E-46 T 23-04-2016 DC74_RS29625 2f838a5de27ad35040f4f6acb4151e56 570 Pfam PF03432 Relaxase/Mobilisation nuclease domain 88 233 4.2E-6 T 23-04-2016 IPR005094 Endonuclease relaxase, MobA/VirD2 DC74_RS04955 dbb41faa87f84adbba2f5e7656208c2a 220 PANTHER PTHR14119:SF1 14 211 3.5E-110 T 23-04-2016 DC74_RS04955 dbb41faa87f84adbba2f5e7656208c2a 220 SUPERFAMILY SSF52499 13 210 2.09E-52 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS04955 dbb41faa87f84adbba2f5e7656208c2a 220 Pfam PF00857 Isochorismatase family 22 172 4.9E-31 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS04955 dbb41faa87f84adbba2f5e7656208c2a 220 PANTHER PTHR14119 14 211 3.5E-110 T 23-04-2016 DC74_RS04955 dbb41faa87f84adbba2f5e7656208c2a 220 Gene3D G3DSA:3.40.50.850 13 211 3.2E-49 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS36310 d8cd357cf3767e670f5f69d7362e0907 548 SUPERFAMILY SSF56801 13 543 1.57E-152 T 23-04-2016 DC74_RS36310 d8cd357cf3767e670f5f69d7362e0907 548 PANTHER PTHR24096 11 538 2.2E-161 T 23-04-2016 DC74_RS36310 d8cd357cf3767e670f5f69d7362e0907 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 530 2.9E-21 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS36310 d8cd357cf3767e670f5f69d7362e0907 548 Gene3D G3DSA:3.40.50.980 202 364 3.1E-38 T 23-04-2016 DC74_RS36310 d8cd357cf3767e670f5f69d7362e0907 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 197 208 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS36310 d8cd357cf3767e670f5f69d7362e0907 548 Gene3D G3DSA:3.40.50.980 19 201 3.5E-36 T 23-04-2016 DC74_RS36310 d8cd357cf3767e670f5f69d7362e0907 548 Pfam PF00501 AMP-binding enzyme 26 446 1.4E-98 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS36310 d8cd357cf3767e670f5f69d7362e0907 548 Gene3D G3DSA:2.30.38.10 365 436 1.0E-28 T 23-04-2016 DC74_RS36310 d8cd357cf3767e670f5f69d7362e0907 548 Gene3D G3DSA:3.30.300.30 441 539 2.1E-31 T 23-04-2016 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 PANTHER PTHR11963 10 510 2.9E-192 T 23-04-2016 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 510 34.371 T 23-04-2016 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 PANTHER PTHR11963:SF13 10 510 2.9E-192 T 23-04-2016 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 20 146 1.5E-25 T 23-04-2016 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 SUPERFAMILY SSF52949 17 147 2.41E-25 T 23-04-2016 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 Gene3D G3DSA:3.40.220.10 16 188 4.0E-39 T 23-04-2016 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 356 363 - T 23-04-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 SUPERFAMILY SSF53187 190 507 8.57E-114 T 23-04-2016 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 PRINTS PR00481 Cytosol aminopeptidase signature 380 395 4.8E-51 T 23-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 PRINTS PR00481 Cytosol aminopeptidase signature 271 288 4.8E-51 T 23-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 PRINTS PR00481 Cytosol aminopeptidase signature 293 314 4.8E-51 T 23-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 PRINTS PR00481 Cytosol aminopeptidase signature 330 351 4.8E-51 T 23-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 PRINTS PR00481 Cytosol aminopeptidase signature 352 372 4.8E-51 T 23-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 196 501 2.8E-116 T 23-04-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 DC74_RS13045 9c787ffc63fa4a82cc5f7df730bd9a33 514 Gene3D G3DSA:3.40.630.10 189 509 1.5E-131 T 23-04-2016 DC74_RS02430 2e8be7444b73c7c4a73cc7c285379463 853 Pfam PF02687 FtsX-like permease family 273 393 3.0E-25 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS02430 2e8be7444b73c7c4a73cc7c285379463 853 Pfam PF02687 FtsX-like permease family 729 846 2.8E-22 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS02430 2e8be7444b73c7c4a73cc7c285379463 853 PANTHER PTHR30489:SF9 1 196 1.9E-149 T 23-04-2016 DC74_RS02430 2e8be7444b73c7c4a73cc7c285379463 853 PANTHER PTHR30489:SF9 246 853 1.9E-149 T 23-04-2016 DC74_RS02430 2e8be7444b73c7c4a73cc7c285379463 853 PANTHER PTHR30489 1 196 1.9E-149 T 23-04-2016 DC74_RS02430 2e8be7444b73c7c4a73cc7c285379463 853 PANTHER PTHR30489 246 853 1.9E-149 T 23-04-2016 DC74_RS02430 2e8be7444b73c7c4a73cc7c285379463 853 Pfam PF12704 MacB-like periplasmic core domain 496 695 2.8E-13 T 23-04-2016 IPR025857 MacB-like periplasmic core domain DC74_RS02430 2e8be7444b73c7c4a73cc7c285379463 853 Pfam PF12704 MacB-like periplasmic core domain 17 235 8.0E-12 T 23-04-2016 IPR025857 MacB-like periplasmic core domain DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 SUPERFAMILY SSF48264 21 403 1.44E-89 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 PRINTS PR00359 B-class P450 signature 275 286 8.5E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 PRINTS PR00359 B-class P450 signature 156 171 8.5E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 PRINTS PR00359 B-class P450 signature 352 363 8.5E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 PRINTS PR00359 B-class P450 signature 92 103 8.5E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 PRINTS PR00359 B-class P450 signature 139 155 8.5E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 PRINTS PR00359 B-class P450 signature 194 216 8.5E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 PRINTS PR00359 B-class P450 signature 322 337 8.5E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 PRINTS PR00359 B-class P450 signature 294 321 8.5E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 PRINTS PR00359 B-class P450 signature 343 352 8.5E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 Gene3D G3DSA:1.10.630.10 14 403 1.3E-116 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 Pfam PF00067 Cytochrome P450 193 373 2.1E-22 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS29280 dbbcc4a5c45ae2213b5f23c5dd4d5d2a 403 PANTHER PTHR11712 13 403 1.0E-83 T 23-04-2016 DC74_RS09170 de4fc6aae9152237c939a72a74b482b2 461 Pfam PF13529 Peptidase_C39 like family 248 399 6.2E-29 T 23-04-2016 DC74_RS30850 6e67e753726f89242420088841e7d0e3 177 PANTHER PTHR11055 3 176 5.7E-102 T 23-04-2016 DC74_RS30850 6e67e753726f89242420088841e7d0e3 177 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 3 169 2.4E-57 T 23-04-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: REACT_13433|UniPathway: UPA00140 DC74_RS30850 6e67e753726f89242420088841e7d0e3 177 SUPERFAMILY SSF52540 3 174 1.24E-33 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30850 6e67e753726f89242420088841e7d0e3 177 PANTHER PTHR11055:SF15 3 176 5.7E-102 T 23-04-2016 DC74_RS30850 6e67e753726f89242420088841e7d0e3 177 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 1 175 33.581 T 23-04-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: REACT_13433|UniPathway: UPA00140 DC74_RS30850 6e67e753726f89242420088841e7d0e3 177 Gene3D G3DSA:3.40.50.300 2 176 1.1E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30850 6e67e753726f89242420088841e7d0e3 177 Pfam PF01583 Adenylylsulphate kinase 3 159 2.8E-58 T 23-04-2016 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 32 536 1.8E-212 T 23-04-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PANTHER PTHR10422:SF6 17 550 7.8E-288 T 23-04-2016 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 41 483 6.6E-144 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 261 315 - T 23-04-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PANTHER PTHR10422 17 550 7.8E-288 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 SUPERFAMILY SSF81442 29 539 1.7E-174 T 23-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 Gene3D G3DSA:1.20.210.10 30 545 8.3E-191 T 23-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 105 129 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 180 198 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 259 280 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 31 56 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 148 160 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 362 380 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 78 101 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 238 259 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 327 348 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 390 409 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 209 228 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 305 320 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS13710 021c4db65b1a5c200f731549bd8ed308 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 440 461 6.2E-101 T 23-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 SMART SM00662 18 225 5.4E-93 T 23-04-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 Gene3D G3DSA:2.170.120.12 62 168 3.8E-44 T 23-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 SUPERFAMILY SSF47789 247 318 8.76E-23 T 23-04-2016 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 3.3E-113 T 23-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 9.4E-24 T 23-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 PANTHER PTHR32108:SF0 12 324 3.7E-132 T 23-04-2016 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 4.1E-19 T 23-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 33.901 T 23-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 Gene3D G3DSA:3.30.1360.10 8 61 3.6E-10 T 23-04-2016 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 SUPERFAMILY SSF55257 170 220 1.14E-23 T 23-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 SUPERFAMILY SSF55257 15 48 1.14E-23 T 23-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 SUPERFAMILY SSF56553 48 169 8.63E-41 T 23-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 PANTHER PTHR32108 12 324 3.7E-132 T 23-04-2016 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 Gene3D G3DSA:1.10.150.20 245 318 6.3E-31 T 23-04-2016 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 Gene3D G3DSA:3.30.1360.10 171 217 4.0E-4 T 23-04-2016 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 302 2.8E-25 T 23-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS05205 b3ea149c8a1306dc783608fc8cb5fbb8 338 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 317 2.0E-31 T 23-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS34095 6af1d89287cf4197d6251f8100c7a0fc 252 PANTHER PTHR24220:SF365 6 215 2.1E-81 T 23-04-2016 IPR017875 Aliphatic sulfonates import ATP-binding protein SsuB GO:0005215|GO:0005524|GO:0005886|GO:0006810 DC74_RS34095 6af1d89287cf4197d6251f8100c7a0fc 252 Gene3D G3DSA:3.40.50.300 5 200 7.2E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34095 6af1d89287cf4197d6251f8100c7a0fc 252 ProSitePatterns PS00211 ABC transporters family signature. 119 133 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS34095 6af1d89287cf4197d6251f8100c7a0fc 252 PANTHER PTHR24220 6 215 2.1E-81 T 23-04-2016 DC74_RS34095 6af1d89287cf4197d6251f8100c7a0fc 252 SUPERFAMILY SSF52540 6 202 1.27E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34095 6af1d89287cf4197d6251f8100c7a0fc 252 SMART SM00382 29 196 2.5E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS34095 6af1d89287cf4197d6251f8100c7a0fc 252 Pfam PF00005 ABC transporter 21 146 6.8E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS04480 8be6fccdf39185d7edfbfc713dc1f363 101 Gene3D G3DSA:1.10.1200.10 5 81 1.8E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04480 8be6fccdf39185d7edfbfc713dc1f363 101 Pfam PF00550 Phosphopantetheine attachment site 23 72 7.9E-6 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS04480 8be6fccdf39185d7edfbfc713dc1f363 101 SUPERFAMILY SSF47336 11 82 3.14E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05170 4c6a0787fb1a9a839cac881c423e013d 124 Pfam PF13633 Prokaryotic N-terminal methylation site 21 43 9.4E-9 T 23-04-2016 IPR012902 Prokaryotic N-terminal methylation site DC74_RS05170 4c6a0787fb1a9a839cac881c423e013d 124 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 22 44 2.3E-8 T 23-04-2016 IPR012902 Prokaryotic N-terminal methylation site DC74_RS05170 4c6a0787fb1a9a839cac881c423e013d 124 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 22 42 - T 23-04-2016 IPR012902 Prokaryotic N-terminal methylation site DC74_RS05170 4c6a0787fb1a9a839cac881c423e013d 124 PANTHER PTHR30093 9 79 1.3E-15 T 23-04-2016 DC74_RS05170 4c6a0787fb1a9a839cac881c423e013d 124 SUPERFAMILY SSF54523 24 84 9.42E-16 T 23-04-2016 DC74_RS05170 4c6a0787fb1a9a839cac881c423e013d 124 PRINTS PR00885 Bacterial general secretion pathway protein H signature 19 33 3.3E-5 T 23-04-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 DC74_RS05170 4c6a0787fb1a9a839cac881c423e013d 124 PRINTS PR00885 Bacterial general secretion pathway protein H signature 34 48 3.3E-5 T 23-04-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 DC74_RS05170 4c6a0787fb1a9a839cac881c423e013d 124 Gene3D G3DSA:3.30.700.10 24 79 5.9E-7 T 23-04-2016 DC74_RS29310 9be949affcc6e9e051a2134d9ffdf0ac 479 Gene3D G3DSA:3.40.1140.10 385 410 7.5E-10 T 23-04-2016 DC74_RS29310 9be949affcc6e9e051a2134d9ffdf0ac 479 Gene3D G3DSA:3.40.1140.10 13 84 7.5E-10 T 23-04-2016 DC74_RS29310 9be949affcc6e9e051a2134d9ffdf0ac 479 SUPERFAMILY SSF52540 24 70 1.67E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29310 9be949affcc6e9e051a2134d9ffdf0ac 479 SUPERFAMILY SSF52540 366 412 1.67E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28995 976208a71b8dc0bfd2ab754af16bff41 256 Gene3D G3DSA:3.90.79.10 3 167 4.3E-47 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS28995 976208a71b8dc0bfd2ab754af16bff41 256 PANTHER PTHR22769:SF42 2 231 8.9E-79 T 23-04-2016 DC74_RS28995 976208a71b8dc0bfd2ab754af16bff41 256 PRINTS PR00502 NUDIX hydrolase family signature 58 73 1.9E-5 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS28995 976208a71b8dc0bfd2ab754af16bff41 256 PRINTS PR00502 NUDIX hydrolase family signature 44 58 1.9E-5 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS28995 976208a71b8dc0bfd2ab754af16bff41 256 SUPERFAMILY SSF46785 179 249 2.09E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28995 976208a71b8dc0bfd2ab754af16bff41 256 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS28995 976208a71b8dc0bfd2ab754af16bff41 256 Pfam PF00293 NUDIX domain 15 143 2.7E-18 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS28995 976208a71b8dc0bfd2ab754af16bff41 256 SUPERFAMILY SSF55811 4 176 2.71E-28 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS28995 976208a71b8dc0bfd2ab754af16bff41 256 PANTHER PTHR22769 2 231 8.9E-79 T 23-04-2016 DC74_RS28995 976208a71b8dc0bfd2ab754af16bff41 256 Gene3D G3DSA:1.10.10.10 171 244 5.5E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06735 124240ee5a0c93d3af30f77d41cbbabc 212 PANTHER PTHR13256:SF19 9 210 7.2E-25 T 23-04-2016 DC74_RS06735 124240ee5a0c93d3af30f77d41cbbabc 212 Pfam PF13302 Acetyltransferase (GNAT) domain 47 164 1.1E-13 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS06735 124240ee5a0c93d3af30f77d41cbbabc 212 PANTHER PTHR13256 9 210 7.2E-25 T 23-04-2016 DC74_RS06735 124240ee5a0c93d3af30f77d41cbbabc 212 SUPERFAMILY SSF55729 45 170 1.02E-20 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06735 124240ee5a0c93d3af30f77d41cbbabc 212 Gene3D G3DSA:3.40.630.30 8 174 4.1E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS14395 8d78e7aec66bd63c23dece0d428afe23 230 Gene3D G3DSA:1.10.3210.10 49 173 6.3E-9 T 23-04-2016 IPR006674 HD domain DC74_RS14395 8d78e7aec66bd63c23dece0d428afe23 230 SUPERFAMILY SSF109604 48 180 1.22E-10 T 23-04-2016 DC74_RS39375 580b4d5ee4b3d4d1892bab4a6657bb32 381 SUPERFAMILY SSF88946 4 85 3.02E-12 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS39375 580b4d5ee4b3d4d1892bab4a6657bb32 381 SUPERFAMILY SSF88659 94 149 3.71E-8 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS39375 580b4d5ee4b3d4d1892bab4a6657bb32 381 Gene3D G3DSA:1.10.10.10 93 149 2.2E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39375 580b4d5ee4b3d4d1892bab4a6657bb32 381 PANTHER PTHR30173 3 347 6.2E-142 T 23-04-2016 DC74_RS39375 580b4d5ee4b3d4d1892bab4a6657bb32 381 Gene3D G3DSA:1.10.1740.10 4 89 8.2E-12 T 23-04-2016 DC74_RS39375 580b4d5ee4b3d4d1892bab4a6657bb32 381 Pfam PF08281 Sigma-70, region 4 98 148 4.4E-8 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS39375 580b4d5ee4b3d4d1892bab4a6657bb32 381 Pfam PF04542 Sigma-70 region 2 9 68 7.0E-9 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS39375 580b4d5ee4b3d4d1892bab4a6657bb32 381 PANTHER PTHR30173:SF15 3 347 6.2E-142 T 23-04-2016 DC74_RS10585 53bcddbb05f7ad0c4aff93cc09f83d9f 127 Pfam PF02656 Domain of unknown function (DUF202) 24 89 1.0E-14 T 23-04-2016 IPR003807 Domain of unknown function DUF202 DC74_RS10585 53bcddbb05f7ad0c4aff93cc09f83d9f 127 PANTHER PTHR34187 4 123 9.4E-24 T 23-04-2016 DC74_RS28165 108e06a8a08a927c2a4841ab1df2a008 113 Pfam PF02021 Uncharacterised protein family UPF0102 5 96 1.6E-26 T 23-04-2016 IPR003509 Uncharacterised protein family UPF0102 DC74_RS28165 108e06a8a08a927c2a4841ab1df2a008 113 Gene3D G3DSA:3.40.1350.10 4 112 7.7E-35 T 23-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 DC74_RS28165 108e06a8a08a927c2a4841ab1df2a008 113 PANTHER PTHR34039 1 112 9.9E-35 T 23-04-2016 DC74_RS28165 108e06a8a08a927c2a4841ab1df2a008 113 PANTHER PTHR34039:SF1 1 112 9.9E-35 T 23-04-2016 DC74_RS28165 108e06a8a08a927c2a4841ab1df2a008 113 SUPERFAMILY SSF52980 3 97 1.5E-19 T 23-04-2016 IPR011335 Restriction endonuclease type II-like DC74_RS28165 108e06a8a08a927c2a4841ab1df2a008 113 Hamap MF_00048 UPF0102 protein YraN [yraN]. 1 109 17.156 T 23-04-2016 IPR003509 Uncharacterised protein family UPF0102 DC74_RS14715 9af1a6adcb6e32179a7022ca162cb3a8 679 Pfam PF11308 Glycosyl hydrolases related to GH101 family, GH129 312 630 6.3E-91 T 23-04-2016 IPR021459 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 DC74_RS00705 58d82ae50c715e98b1839836977ca485 249 Gene3D G3DSA:3.90.550.10 19 245 8.7E-53 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS00705 58d82ae50c715e98b1839836977ca485 249 PANTHER PTHR22572:SF107 20 243 2.7E-56 T 23-04-2016 DC74_RS00705 58d82ae50c715e98b1839836977ca485 249 Pfam PF00483 Nucleotidyl transferase 21 240 6.5E-20 T 23-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 DC74_RS00705 58d82ae50c715e98b1839836977ca485 249 SUPERFAMILY SSF53448 19 243 4.73E-52 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS00705 58d82ae50c715e98b1839836977ca485 249 PANTHER PTHR22572 20 243 2.7E-56 T 23-04-2016 DC74_RS03050 5cccc110f6b073e6e12eadb5f4568e1f 202 PANTHER PTHR30108 1 182 1.9E-80 T 23-04-2016 DC74_RS03050 5cccc110f6b073e6e12eadb5f4568e1f 202 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 1 176 2.6E-75 T 23-04-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 DC74_RS03050 5cccc110f6b073e6e12eadb5f4568e1f 202 Pfam PF02441 Flavoprotein 1 119 4.1E-21 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS03050 5cccc110f6b073e6e12eadb5f4568e1f 202 SUPERFAMILY SSF52507 1 178 1.57E-54 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS03050 5cccc110f6b073e6e12eadb5f4568e1f 202 Gene3D G3DSA:3.40.50.1950 1 184 2.3E-73 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS03050 5cccc110f6b073e6e12eadb5f4568e1f 202 PANTHER PTHR30108:SF2 1 182 1.9E-80 T 23-04-2016 DC74_RS03050 5cccc110f6b073e6e12eadb5f4568e1f 202 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 178 33.148 T 23-04-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 DC74_RS36755 8f557b51e0e0575d45506eac279ad9b0 225 PANTHER PTHR30086:SF2 1 101 5.4E-46 T 23-04-2016 DC74_RS36755 8f557b51e0e0575d45506eac279ad9b0 225 PANTHER PTHR30086:SF2 120 215 5.4E-46 T 23-04-2016 DC74_RS36755 8f557b51e0e0575d45506eac279ad9b0 225 PANTHER PTHR30086 1 101 5.4E-46 T 23-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 DC74_RS36755 8f557b51e0e0575d45506eac279ad9b0 225 PANTHER PTHR30086 120 215 5.4E-46 T 23-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 DC74_RS36755 8f557b51e0e0575d45506eac279ad9b0 225 Pfam PF01810 LysE type translocator 15 221 2.2E-33 T 23-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 DC74_RS36755 8f557b51e0e0575d45506eac279ad9b0 225 PIRSF PIRSF006324 1 224 1.3E-45 T 23-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 DC74_RS26545 1a5d8c0e8079389a3dc83283f0d302df 312 PANTHER PTHR18919:SF109 27 312 9.2E-100 T 23-04-2016 DC74_RS26545 1a5d8c0e8079389a3dc83283f0d302df 312 Gene3D G3DSA:3.40.47.10 1 160 3.7E-59 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS26545 1a5d8c0e8079389a3dc83283f0d302df 312 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 311 58.033 T 23-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS26545 1a5d8c0e8079389a3dc83283f0d302df 312 PANTHER PTHR18919 27 312 9.2E-100 T 23-04-2016 DC74_RS26545 1a5d8c0e8079389a3dc83283f0d302df 312 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 222 310 1.3E-24 T 23-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS26545 1a5d8c0e8079389a3dc83283f0d302df 312 SUPERFAMILY SSF53901 3 311 6.04E-58 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS26545 1a5d8c0e8079389a3dc83283f0d302df 312 Gene3D G3DSA:3.40.47.10 161 311 2.6E-38 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS26545 1a5d8c0e8079389a3dc83283f0d302df 312 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 173 1.1E-26 T 23-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS26545 1a5d8c0e8079389a3dc83283f0d302df 312 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 310 2.1E-89 T 23-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS32305 1282d238d785e502b6102e9b83ed043f 87 ProSitePatterns PS00012 Phosphopantetheine attachment site. 37 52 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS32305 1282d238d785e502b6102e9b83ed043f 87 Gene3D G3DSA:1.10.1200.10 6 84 4.3E-18 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS32305 1282d238d785e502b6102e9b83ed043f 87 SUPERFAMILY SSF47336 5 86 3.53E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS32305 1282d238d785e502b6102e9b83ed043f 87 SMART SM00823 Phosphopantetheine attachment site 12 82 0.0013 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS32305 1282d238d785e502b6102e9b83ed043f 87 Pfam PF00550 Phosphopantetheine attachment site 10 78 1.0E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29505 b4b390ea766a525c73a7ed6a7eaf5cd2 236 Gene3D G3DSA:3.90.470.20 106 183 1.2E-4 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS29505 b4b390ea766a525c73a7ed6a7eaf5cd2 236 PANTHER PTHR38096 42 224 2.4E-46 T 23-04-2016 DC74_RS29505 b4b390ea766a525c73a7ed6a7eaf5cd2 236 PRINTS PR01399 Enterobactin synthetase component D signature 70 88 2.3E-20 T 23-04-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UniPathway: UPA00017 DC74_RS29505 b4b390ea766a525c73a7ed6a7eaf5cd2 236 PRINTS PR01399 Enterobactin synthetase component D signature 147 163 2.3E-20 T 23-04-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UniPathway: UPA00017 DC74_RS29505 b4b390ea766a525c73a7ed6a7eaf5cd2 236 PRINTS PR01399 Enterobactin synthetase component D signature 40 60 2.3E-20 T 23-04-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UniPathway: UPA00017 DC74_RS29505 b4b390ea766a525c73a7ed6a7eaf5cd2 236 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 105 183 1.0E-8 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS29505 b4b390ea766a525c73a7ed6a7eaf5cd2 236 SUPERFAMILY SSF56214 104 216 3.49E-11 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 SUPERFAMILY SSF53474 25 374 3.8E-70 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 56 225 1.8E-19 T 23-04-2016 IPR005674 CocE/Serine esterase GO:0016787 DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 PANTHER PTHR11731 36 237 9.2E-70 T 23-04-2016 DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 PANTHER PTHR11731 260 359 9.2E-70 T 23-04-2016 DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 51 324 2.0E-59 T 23-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 PANTHER PTHR11731:SF148 36 237 9.2E-70 T 23-04-2016 DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 PANTHER PTHR11731:SF148 260 359 9.2E-70 T 23-04-2016 DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 SMART SM00939 339 597 2.6E-38 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 SUPERFAMILY SSF49785 410 601 1.24E-30 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 Gene3D G3DSA:2.60.120.260 367 473 1.2E-36 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 Gene3D G3DSA:2.60.120.260 520 600 1.2E-36 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 351 597 7.8E-39 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 Gene3D G3DSA:3.40.50.1820 279 366 2.9E-56 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS33100 c0c55ed595ee6a925deec91744b20b95 641 Gene3D G3DSA:3.40.50.1820 32 219 2.9E-56 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34275 1f9e62507d18b260f4ddb141a3b0c754 225 Pfam PF12697 Alpha/beta hydrolase family 35 186 3.3E-9 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS34275 1f9e62507d18b260f4ddb141a3b0c754 225 Gene3D G3DSA:3.40.50.1820 16 205 2.9E-20 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34275 1f9e62507d18b260f4ddb141a3b0c754 225 SUPERFAMILY SSF53474 13 208 1.16E-23 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS22440 8472acad113f7fc0d3ec5ed2a11073dc 668 PANTHER PTHR23076 113 622 5.3E-301 T 23-04-2016 DC74_RS22440 8472acad113f7fc0d3ec5ed2a11073dc 668 SUPERFAMILY SSF52540 161 411 1.13E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22440 8472acad113f7fc0d3ec5ed2a11073dc 668 Gene3D G3DSA:1.10.8.60 348 414 1.9E-23 T 23-04-2016 DC74_RS22440 8472acad113f7fc0d3ec5ed2a11073dc 668 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 120 610 6.1E-232 T 23-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 DC74_RS22440 8472acad113f7fc0d3ec5ed2a11073dc 668 Pfam PF01434 Peptidase family M41 404 609 3.3E-80 T 23-04-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 DC74_RS22440 8472acad113f7fc0d3ec5ed2a11073dc 668 Gene3D G3DSA:3.40.50.300 163 347 5.2E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22440 8472acad113f7fc0d3ec5ed2a11073dc 668 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 339 9.3E-45 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS22440 8472acad113f7fc0d3ec5ed2a11073dc 668 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 619 37.185 T 23-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 DC74_RS22440 8472acad113f7fc0d3ec5ed2a11073dc 668 SMART SM00382 203 342 6.2E-25 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS22440 8472acad113f7fc0d3ec5ed2a11073dc 668 SUPERFAMILY SSF140990 421 616 1.7E-73 T 23-04-2016 DC74_RS22440 8472acad113f7fc0d3ec5ed2a11073dc 668 ProSitePatterns PS00674 AAA-protein family signature. 310 328 - T 23-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DC74_RS01340 65aaa18680b1480ac162fc4d5765b0cc 171 Pfam PF12973 ChrR Cupin-like domain 39 124 5.4E-11 T 23-04-2016 IPR025979 ChrR-like cupin domain DC74_RS01340 65aaa18680b1480ac162fc4d5765b0cc 171 SUPERFAMILY SSF51182 34 154 1.92E-22 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS01340 65aaa18680b1480ac162fc4d5765b0cc 171 Gene3D G3DSA:2.60.120.10 34 166 3.4E-41 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS11490 fc7095d92f96383c8f645bdd00d52ae0 222 PANTHER PTHR22789:SF0 1 220 8.8E-81 T 23-04-2016 DC74_RS11490 fc7095d92f96383c8f645bdd00d52ae0 222 SMART SM01007 13 186 2.2E-56 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal DC74_RS11490 fc7095d92f96383c8f645bdd00d52ae0 222 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 14 185 1.3E-47 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal DC74_RS11490 fc7095d92f96383c8f645bdd00d52ae0 222 SUPERFAMILY SSF53639 9 216 5.3E-59 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal DC74_RS11490 fc7095d92f96383c8f645bdd00d52ae0 222 Gene3D G3DSA:3.40.225.10 9 217 8.6E-66 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal DC74_RS11490 fc7095d92f96383c8f645bdd00d52ae0 222 PANTHER PTHR22789 1 220 8.8E-81 T 23-04-2016 DC74_RS01395 2e56f52525dbc78ba1c2d3626789ce78 278 SUPERFAMILY SSF103481 41 135 1.83E-5 T 23-04-2016 DC74_RS01395 2e56f52525dbc78ba1c2d3626789ce78 278 Pfam PF00892 EamA-like transporter family 146 275 1.0E-8 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS01395 2e56f52525dbc78ba1c2d3626789ce78 278 SUPERFAMILY SSF103481 184 277 6.15E-10 T 23-04-2016 DC74_RS01395 2e56f52525dbc78ba1c2d3626789ce78 278 PANTHER PTHR22911 4 277 6.9E-26 T 23-04-2016 DC74_RS01395 2e56f52525dbc78ba1c2d3626789ce78 278 PANTHER PTHR22911:SF54 4 277 6.9E-26 T 23-04-2016 DC74_RS28395 6cde794658075bcd2637c91a5c749c86 281 PIRSF PIRSF021603 2 281 6.1E-133 T 23-04-2016 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like DC74_RS28395 6cde794658075bcd2637c91a5c749c86 281 PANTHER PTHR23091 111 277 8.8E-43 T 23-04-2016 DC74_RS28395 6cde794658075bcd2637c91a5c749c86 281 PANTHER PTHR23091:SF122 111 277 8.8E-43 T 23-04-2016 DC74_RS28395 6cde794658075bcd2637c91a5c749c86 281 Pfam PF13312 Domain of unknown function (DUF4081) 48 152 6.6E-42 T 23-04-2016 IPR025289 Domain of unknown function DUF4081 DC74_RS28395 6cde794658075bcd2637c91a5c749c86 281 SUPERFAMILY SSF55729 7 276 1.03E-22 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS28395 6cde794658075bcd2637c91a5c749c86 281 Gene3D G3DSA:3.40.630.30 130 277 8.9E-22 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS28395 6cde794658075bcd2637c91a5c749c86 281 Pfam PF00583 Acetyltransferase (GNAT) family 208 271 7.4E-11 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS06935 5b0c9b8b6e6056cb30cc183262ad63fe 270 Gene3D G3DSA:3.40.50.150 64 265 1.0E-37 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS06935 5b0c9b8b6e6056cb30cc183262ad63fe 270 SUPERFAMILY SSF53335 50 248 3.19E-41 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS06935 5b0c9b8b6e6056cb30cc183262ad63fe 270 PANTHER PTHR10108:SF877 51 266 6.0E-23 T 23-04-2016 DC74_RS06935 5b0c9b8b6e6056cb30cc183262ad63fe 270 PANTHER PTHR10108 51 266 6.0E-23 T 23-04-2016 DC74_RS06935 5b0c9b8b6e6056cb30cc183262ad63fe 270 Pfam PF13649 Methyltransferase domain 89 191 2.5E-18 T 23-04-2016 DC74_RS38175 c0d3d620ef73ac78ad08a549f836fab0 311 Gene3D G3DSA:1.10.10.10 3 88 2.5E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38175 c0d3d620ef73ac78ad08a549f836fab0 311 Gene3D G3DSA:3.40.190.10 180 272 6.6E-14 T 23-04-2016 DC74_RS38175 c0d3d620ef73ac78ad08a549f836fab0 311 SUPERFAMILY SSF46785 2 112 1.48E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38175 c0d3d620ef73ac78ad08a549f836fab0 311 PANTHER PTHR30346 2 297 1.0E-70 T 23-04-2016 DC74_RS38175 c0d3d620ef73ac78ad08a549f836fab0 311 Gene3D G3DSA:3.40.190.10 92 179 1.6E-12 T 23-04-2016 DC74_RS38175 c0d3d620ef73ac78ad08a549f836fab0 311 Pfam PF03466 LysR substrate binding domain 90 299 5.6E-24 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS38175 c0d3d620ef73ac78ad08a549f836fab0 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 7.7E-20 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS38175 c0d3d620ef73ac78ad08a549f836fab0 311 PANTHER PTHR30346:SF2 2 297 1.0E-70 T 23-04-2016 DC74_RS38175 c0d3d620ef73ac78ad08a549f836fab0 311 SUPERFAMILY SSF53850 91 301 4.34E-23 T 23-04-2016 DC74_RS33875 1e7468977245321924dde8d989bd0bfa 470 SUPERFAMILY SSF51206 87 212 8.25E-18 T 23-04-2016 IPR018490 Cyclic nucleotide-binding-like DC74_RS33875 1e7468977245321924dde8d989bd0bfa 470 PANTHER PTHR24567:SF37 20 218 1.9E-162 T 23-04-2016 DC74_RS33875 1e7468977245321924dde8d989bd0bfa 470 PANTHER PTHR24567:SF37 286 470 1.9E-162 T 23-04-2016 DC74_RS33875 1e7468977245321924dde8d989bd0bfa 470 SMART SM00100 97 220 2.1E-7 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS33875 1e7468977245321924dde8d989bd0bfa 470 Gene3D G3DSA:2.60.120.10 89 215 1.1E-16 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS33875 1e7468977245321924dde8d989bd0bfa 470 PANTHER PTHR24567 20 218 1.9E-162 T 23-04-2016 DC74_RS33875 1e7468977245321924dde8d989bd0bfa 470 PANTHER PTHR24567 286 470 1.9E-162 T 23-04-2016 DC74_RS33875 1e7468977245321924dde8d989bd0bfa 470 Pfam PF00027 Cyclic nucleotide-binding domain 117 203 7.7E-10 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS05670 568fb7dfe8c7007802217fad8e24af0d 204 Gene3D G3DSA:1.10.10.60 11 70 5.0E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS05670 568fb7dfe8c7007802217fad8e24af0d 204 PANTHER PTHR30055:SF11 6 202 2.4E-47 T 23-04-2016 DC74_RS05670 568fb7dfe8c7007802217fad8e24af0d 204 PANTHER PTHR30055 6 202 2.4E-47 T 23-04-2016 DC74_RS05670 568fb7dfe8c7007802217fad8e24af0d 204 SUPERFAMILY SSF48498 88 199 5.28E-26 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS05670 568fb7dfe8c7007802217fad8e24af0d 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 6.5E-16 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS05670 568fb7dfe8c7007802217fad8e24af0d 204 Gene3D G3DSA:1.10.357.10 71 199 2.1E-24 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS05670 568fb7dfe8c7007802217fad8e24af0d 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 8.51E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS05670 568fb7dfe8c7007802217fad8e24af0d 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 8.51E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS05670 568fb7dfe8c7007802217fad8e24af0d 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 67 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS05670 568fb7dfe8c7007802217fad8e24af0d 204 SUPERFAMILY SSF46689 10 91 1.08E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PANTHER PTHR24322 188 220 3.1E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PANTHER PTHR24322 39 172 3.1E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 Gene3D G3DSA:3.40.50.720 30 279 1.9E-75 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 117 128 6.3E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 188 207 6.3E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 176 6.3E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PANTHER PTHR24322:SF390 188 220 3.1E-50 T 23-04-2016 DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 SUPERFAMILY SSF51735 34 279 8.89E-70 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 175 203 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 41 277 2.1E-51 T 23-04-2016 DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PANTHER PTHR24322:SF390 39 172 3.1E-50 T 23-04-2016 DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 35 219 4.4E-4 T 23-04-2016 DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 226 2.9E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 242 262 2.9E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 36 53 2.9E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 207 2.9E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 178 2.9E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32325 4301ac6da653664825925eeaba8f372d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 128 2.9E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS27770 2c8833903d2bb0e303e3eb4323457409 205 PANTHER PTHR30328:SF6 6 204 8.8E-35 T 23-04-2016 DC74_RS27770 2c8833903d2bb0e303e3eb4323457409 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 4.0E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS27770 2c8833903d2bb0e303e3eb4323457409 205 SUPERFAMILY SSF46689 6 91 1.08E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS27770 2c8833903d2bb0e303e3eb4323457409 205 PANTHER PTHR30328 6 204 8.8E-35 T 23-04-2016 DC74_RS27770 2c8833903d2bb0e303e3eb4323457409 205 SUPERFAMILY SSF48498 86 197 3.62E-12 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS27770 2c8833903d2bb0e303e3eb4323457409 205 Pfam PF13977 Bacterial transcriptional repressor 88 198 3.5E-21 T 23-04-2016 DC74_RS27770 2c8833903d2bb0e303e3eb4323457409 205 Gene3D G3DSA:1.10.357.10 10 203 4.4E-37 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS16970 984495f37c059f8b6b8b81f6736daca4 129 Pfam PF06262 Zinicin-like metallopeptidase 54 124 1.7E-9 T 23-04-2016 IPR010428 Zinicin-like metallopeptidase DC74_RS16970 984495f37c059f8b6b8b81f6736daca4 129 SUPERFAMILY SSF55486 16 126 4.39E-25 T 23-04-2016 DC74_RS13310 416824b80adfbe07d4c1b8ea734ade06 590 SUPERFAMILY SSF52402 306 570 2.56E-74 T 23-04-2016 DC74_RS13310 416824b80adfbe07d4c1b8ea734ade06 590 SUPERFAMILY SSF56317 3 259 1.7E-56 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS13310 416824b80adfbe07d4c1b8ea734ade06 590 Gene3D G3DSA:3.60.110.10 3 259 2.5E-55 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS13310 416824b80adfbe07d4c1b8ea734ade06 590 PIRSF PIRSF006630 1 590 3.2E-210 T 23-04-2016 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|UniPathway: UPA00253 DC74_RS13310 416824b80adfbe07d4c1b8ea734ade06 590 TIGRFAM TIGR00552 nadE: NAD+ synthetase 322 565 2.1E-57 T 23-04-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 DC74_RS13310 416824b80adfbe07d4c1b8ea734ade06 590 Pfam PF02540 NAD synthase 315 562 5.0E-70 T 23-04-2016 IPR022310 NAD/GMP synthase DC74_RS13310 416824b80adfbe07d4c1b8ea734ade06 590 PANTHER PTHR23090 1 584 1.9E-160 T 23-04-2016 DC74_RS13310 416824b80adfbe07d4c1b8ea734ade06 590 Gene3D G3DSA:3.40.50.620 306 570 4.9E-73 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS13310 416824b80adfbe07d4c1b8ea734ade06 590 Pfam PF00795 Carbon-nitrogen hydrolase 5 260 1.6E-24 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS13310 416824b80adfbe07d4c1b8ea734ade06 590 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 36 51 - T 23-04-2016 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 DC74_RS39665 660df218de0323fe55f5b310138ef0c8 123 Gene3D G3DSA:1.10.10.10 10 117 2.1E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39665 660df218de0323fe55f5b310138ef0c8 123 SUPERFAMILY SSF46785 17 118 1.17E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39665 660df218de0323fe55f5b310138ef0c8 123 PANTHER PTHR33204 10 118 3.1E-55 T 23-04-2016 DC74_RS39665 660df218de0323fe55f5b310138ef0c8 123 PANTHER PTHR33204:SF7 10 118 3.1E-55 T 23-04-2016 DC74_RS39665 660df218de0323fe55f5b310138ef0c8 123 Pfam PF01638 HxlR-like helix-turn-helix 32 117 4.9E-21 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS06840 7d97dfc93ae48bfb97f6d61d6d1e50f3 209 Gene3D G3DSA:3.30.450.20 2 115 4.1E-7 T 23-04-2016 DC74_RS06840 7d97dfc93ae48bfb97f6d61d6d1e50f3 209 SUPERFAMILY SSF55785 41 113 1.08E-6 T 23-04-2016 IPR000014 PAS domain DC74_RS06840 7d97dfc93ae48bfb97f6d61d6d1e50f3 209 SUPERFAMILY SSF46894 127 194 2.01E-11 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS06840 7d97dfc93ae48bfb97f6d61d6d1e50f3 209 Gene3D G3DSA:1.10.10.10 131 193 5.7E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06840 7d97dfc93ae48bfb97f6d61d6d1e50f3 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 134 187 1.2E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06840 7d97dfc93ae48bfb97f6d61d6d1e50f3 209 SMART SM00421 131 188 1.3E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS36320 1b94f2eec7d84cddeab4483d3a1d49d6 327 Gene3D G3DSA:1.20.140.10 187 323 5.6E-32 T 23-04-2016 DC74_RS36320 1b94f2eec7d84cddeab4483d3a1d49d6 327 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 187 316 4.8E-27 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS36320 1b94f2eec7d84cddeab4483d3a1d49d6 327 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 5.2E-13 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS36320 1b94f2eec7d84cddeab4483d3a1d49d6 327 PANTHER PTHR10909 188 308 7.5E-48 T 23-04-2016 DC74_RS36320 1b94f2eec7d84cddeab4483d3a1d49d6 327 PANTHER PTHR10909 1 167 7.5E-48 T 23-04-2016 DC74_RS36320 1b94f2eec7d84cddeab4483d3a1d49d6 327 SUPERFAMILY SSF47203 187 324 3.06E-33 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS36320 1b94f2eec7d84cddeab4483d3a1d49d6 327 Gene3D G3DSA:1.10.540.10 3 117 2.3E-13 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS36320 1b94f2eec7d84cddeab4483d3a1d49d6 327 PANTHER PTHR10909:SF312 188 308 7.5E-48 T 23-04-2016 DC74_RS36320 1b94f2eec7d84cddeab4483d3a1d49d6 327 PANTHER PTHR10909:SF312 1 167 7.5E-48 T 23-04-2016 DC74_RS36320 1b94f2eec7d84cddeab4483d3a1d49d6 327 SUPERFAMILY SSF56645 1 146 1.7E-16 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS02720 0d7efd22bc9477588ff81969156b686d 130 PANTHER PTHR38594:SF1 3 130 4.7E-36 T 23-04-2016 DC74_RS02720 0d7efd22bc9477588ff81969156b686d 130 Pfam PF03610 PTS system fructose IIA component 6 115 4.9E-21 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 DC74_RS02720 0d7efd22bc9477588ff81969156b686d 130 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 5 124 7.0E-31 T 23-04-2016 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain DC74_RS02720 0d7efd22bc9477588ff81969156b686d 130 SUPERFAMILY SSF53062 5 126 4.19E-28 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 DC74_RS02720 0d7efd22bc9477588ff81969156b686d 130 PANTHER PTHR38594 3 130 4.7E-36 T 23-04-2016 DC74_RS02720 0d7efd22bc9477588ff81969156b686d 130 Gene3D G3DSA:3.40.50.510 4 129 9.5E-39 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 DC74_RS04205 2e6aea143c7351ebb5c5c2d60bea482e 315 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 169 4.0E-36 T 23-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 DC74_RS04205 2e6aea143c7351ebb5c5c2d60bea482e 315 PIRSF PIRSF000103 5 299 2.6E-66 T 23-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 DC74_RS04205 2e6aea143c7351ebb5c5c2d60bea482e 315 SUPERFAMILY SSF48179 174 298 1.59E-25 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS04205 2e6aea143c7351ebb5c5c2d60bea482e 315 SUPERFAMILY SSF51735 10 170 9.64E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04205 2e6aea143c7351ebb5c5c2d60bea482e 315 Gene3D G3DSA:1.10.1040.10 176 298 1.1E-29 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS04205 2e6aea143c7351ebb5c5c2d60bea482e 315 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 176 289 2.5E-20 T 23-04-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 DC74_RS04205 2e6aea143c7351ebb5c5c2d60bea482e 315 Gene3D G3DSA:3.40.50.720 9 170 1.2E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04205 2e6aea143c7351ebb5c5c2d60bea482e 315 PANTHER PTHR22981 7 289 1.5E-77 T 23-04-2016 DC74_RS17945 f1f6da18a23f1d9be903c86551f55487 238 PANTHER PTHR31851 19 236 3.7E-64 T 23-04-2016 DC74_RS17945 f1f6da18a23f1d9be903c86551f55487 238 Pfam PF01988 VIT family 23 230 5.9E-58 T 23-04-2016 IPR008217 Ccc1 family DC74_RS03360 62d08833304238ca5f586c4cc3585034 90 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 68 2.6E-20 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS03360 62d08833304238ca5f586c4cc3585034 90 PANTHER PTHR37301 2 79 5.6E-35 T 23-04-2016 DC74_RS03360 62d08833304238ca5f586c4cc3585034 90 SMART SM00530 6 62 9.6E-6 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS03360 62d08833304238ca5f586c4cc3585034 90 Gene3D G3DSA:1.10.260.40 3 68 1.1E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS03360 62d08833304238ca5f586c4cc3585034 90 SUPERFAMILY SSF47413 2 69 2.73E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS06705 1fbd5858b3497d1006568a4972de0238 106 SUPERFAMILY SSF50022 2 98 1.57E-29 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS06705 1fbd5858b3497d1006568a4972de0238 106 Gene3D G3DSA:2.102.10.10 2 101 4.5E-32 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS06705 1fbd5858b3497d1006568a4972de0238 106 PANTHER PTHR21496 2 98 3.4E-28 T 23-04-2016 DC74_RS06705 1fbd5858b3497d1006568a4972de0238 106 PANTHER PTHR21496:SF11 2 98 3.4E-28 T 23-04-2016 DC74_RS06705 1fbd5858b3497d1006568a4972de0238 106 Pfam PF00355 Rieske [2Fe-2S] domain 2 86 1.8E-17 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS21650 bbc5e53a1bb8a5bd417d3ee8fd7d99eb 211 Gene3D G3DSA:3.40.50.2020 2 209 1.6E-73 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS21650 bbc5e53a1bb8a5bd417d3ee8fd7d99eb 211 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 3.5E-76 T 23-04-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 DC74_RS21650 bbc5e53a1bb8a5bd417d3ee8fd7d99eb 211 PANTHER PTHR10285 1 199 1.3E-77 T 23-04-2016 DC74_RS21650 bbc5e53a1bb8a5bd417d3ee8fd7d99eb 211 Pfam PF14681 Uracil phosphoribosyltransferase 5 209 1.5E-64 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS21650 bbc5e53a1bb8a5bd417d3ee8fd7d99eb 211 SUPERFAMILY SSF53271 3 208 1.19E-64 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS21650 bbc5e53a1bb8a5bd417d3ee8fd7d99eb 211 PANTHER PTHR10285:SF46 1 199 1.3E-77 T 23-04-2016 DC74_RS21650 bbc5e53a1bb8a5bd417d3ee8fd7d99eb 211 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 210 43.306 T 23-04-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 DC74_RS34140 70f006d955b1e28fcda7851b26c7fd0a 392 Gene3D G3DSA:3.40.710.10 61 373 4.6E-80 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS34140 70f006d955b1e28fcda7851b26c7fd0a 392 PANTHER PTHR22935 22 370 2.4E-61 T 23-04-2016 DC74_RS34140 70f006d955b1e28fcda7851b26c7fd0a 392 SUPERFAMILY SSF56601 50 374 9.61E-77 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS34140 70f006d955b1e28fcda7851b26c7fd0a 392 Pfam PF00144 Beta-lactamase 57 386 1.5E-62 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS39075 15701d3b75f2a82e3a176e12e5ed4913 373 SUPERFAMILY SSF51735 6 133 1.13E-7 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39075 15701d3b75f2a82e3a176e12e5ed4913 373 Gene3D G3DSA:3.40.50.720 47 132 3.2E-6 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 PANTHER PTHR23501 1 484 2.6E-188 T 23-04-2016 DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 125 149 1.2E-10 T 23-04-2016 DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 5 29 1.2E-10 T 23-04-2016 DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 389 408 1.2E-10 T 23-04-2016 DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 95 115 1.2E-10 T 23-04-2016 DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 190 208 1.2E-10 T 23-04-2016 DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 Gene3D G3DSA:1.20.1250.20 251 409 1.3E-20 T 23-04-2016 DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 Gene3D G3DSA:1.20.1250.20 3 184 3.2E-34 T 23-04-2016 DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 Gene3D G3DSA:1.20.1250.20 456 482 1.3E-20 T 23-04-2016 DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 2 478 2.9E-86 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 SUPERFAMILY SSF103473 236 408 1.83E-70 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 SUPERFAMILY SSF103473 455 479 1.83E-70 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 SUPERFAMILY SSF103473 2 182 1.83E-70 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 PANTHER PTHR23501:SF73 1 484 2.6E-188 T 23-04-2016 DC74_RS22625 ca486925a09e208e2780e25e374cb8d4 507 Pfam PF07690 Major Facilitator Superfamily 6 398 2.9E-52 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS19685 142b91e857e230e25842f0ab8467b781 356 SUPERFAMILY SSF55326 9 172 9.87E-44 T 23-04-2016 DC74_RS19685 142b91e857e230e25842f0ab8467b781 356 Pfam PF02769 AIR synthase related protein, C-terminal domain 180 344 2.3E-30 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS19685 142b91e857e230e25842f0ab8467b781 356 Gene3D G3DSA:3.30.1330.10 24 172 6.6E-50 T 23-04-2016 IPR016188 PurM-like, N-terminal domain DC74_RS19685 142b91e857e230e25842f0ab8467b781 356 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 8 350 40.074 T 23-04-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19685 142b91e857e230e25842f0ab8467b781 356 Pfam PF00586 AIR synthase related protein, N-terminal domain 64 167 1.1E-15 T 23-04-2016 IPR016188 PurM-like, N-terminal domain DC74_RS19685 142b91e857e230e25842f0ab8467b781 356 SUPERFAMILY SSF56042 176 345 1.17E-50 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS19685 142b91e857e230e25842f0ab8467b781 356 PANTHER PTHR10520 3 341 6.5E-164 T 23-04-2016 DC74_RS19685 142b91e857e230e25842f0ab8467b781 356 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 9 340 3.3E-124 T 23-04-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19685 142b91e857e230e25842f0ab8467b781 356 Gene3D G3DSA:3.90.650.10 176 347 2.4E-61 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS33340 05c39905af904574cf380e63d0f9ac7a 149 Gene3D G3DSA:3.30.450.30 13 138 2.1E-22 T 23-04-2016 DC74_RS33340 05c39905af904574cf380e63d0f9ac7a 149 Pfam PF03259 Roadblock/LC7 domain 22 112 1.5E-24 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS33340 05c39905af904574cf380e63d0f9ac7a 149 SUPERFAMILY SSF103196 15 141 5.76E-27 T 23-04-2016 DC74_RS33340 05c39905af904574cf380e63d0f9ac7a 149 SMART SM00960 22 112 4.5E-26 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS33340 05c39905af904574cf380e63d0f9ac7a 149 PANTHER PTHR36222 10 149 3.0E-46 T 23-04-2016 DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 SMART SM00052 656 909 8.3E-36 T 23-04-2016 IPR001633 EAL domain DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 SMART SM00267 469 646 6.5E-57 T 23-04-2016 IPR000160 GGDEF domain DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 476 645 1.0E-40 T 23-04-2016 IPR000160 GGDEF domain DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 PANTHER PTHR10799:SF774 325 476 3.3E-49 T 23-04-2016 DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 PANTHER PTHR10799:SF774 513 763 3.3E-49 T 23-04-2016 DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 Pfam PF00563 EAL domain 663 904 9.7E-49 T 23-04-2016 IPR001633 EAL domain DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 349 476 3.0E-12 T 23-04-2016 IPR000014 PAS domain DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 Gene3D G3DSA:3.20.20.450 659 916 3.3E-70 T 23-04-2016 IPR001633 EAL domain DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 Gene3D G3DSA:3.30.70.270 482 654 2.5E-55 T 23-04-2016 DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 SUPERFAMILY SSF55073 485 647 1.1E-44 T 23-04-2016 IPR029787 Nucleotide cyclase DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 Pfam PF00990 Diguanylate cyclase, GGDEF domain 480 641 3.2E-42 T 23-04-2016 IPR000160 GGDEF domain DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 SUPERFAMILY SSF141868 662 915 4.45E-51 T 23-04-2016 IPR001633 EAL domain DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 SUPERFAMILY SSF55785 344 467 6.42E-15 T 23-04-2016 IPR000014 PAS domain DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 Pfam PF08448 PAS fold 361 471 1.4E-7 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 Gene3D G3DSA:3.30.450.20 345 469 5.5E-17 T 23-04-2016 DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 PANTHER PTHR10799 325 476 3.3E-49 T 23-04-2016 DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 PANTHER PTHR10799 513 763 3.3E-49 T 23-04-2016 DC74_RS27680 0af3cb396cab9bee6f0dc1294613bae1 958 SMART SM00091 352 418 4.1E-9 T 23-04-2016 IPR000014 PAS domain DC74_RS21100 c2db44701fd4735415b38c8747bf3667 303 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS21100 c2db44701fd4735415b38c8747bf3667 303 SMART SM00382 27 204 3.6E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS21100 c2db44701fd4735415b38c8747bf3667 303 PANTHER PTHR24220 5 233 5.8E-83 T 23-04-2016 DC74_RS21100 c2db44701fd4735415b38c8747bf3667 303 PANTHER PTHR24220 250 255 5.8E-83 T 23-04-2016 DC74_RS21100 c2db44701fd4735415b38c8747bf3667 303 PANTHER PTHR24220:SF160 5 233 5.8E-83 T 23-04-2016 DC74_RS21100 c2db44701fd4735415b38c8747bf3667 303 SUPERFAMILY SSF52540 4 216 2.24E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21100 c2db44701fd4735415b38c8747bf3667 303 PANTHER PTHR24220:SF160 250 255 5.8E-83 T 23-04-2016 DC74_RS21100 c2db44701fd4735415b38c8747bf3667 303 Pfam PF00005 ABC transporter 20 157 3.0E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS21100 c2db44701fd4735415b38c8747bf3667 303 Gene3D G3DSA:3.40.50.300 3 216 2.0E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04200 44a278148cfd3d62df6267250700c659 363 PANTHER PTHR35861:SF1 76 360 1.1E-75 T 23-04-2016 DC74_RS04200 44a278148cfd3d62df6267250700c659 363 Pfam PF04984 Phage tail sheath protein 74 357 1.2E-48 T 23-04-2016 IPR007067 Tail sheath protein DC74_RS04200 44a278148cfd3d62df6267250700c659 363 PANTHER PTHR35861 76 360 1.1E-75 T 23-04-2016 DC74_RS40585 9d0aa81623a11b96b18375f87b35ce86 604 SUPERFAMILY SSF49899 3 154 1.22E-24 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS40585 9d0aa81623a11b96b18375f87b35ce86 604 SUPERFAMILY SSF49899 187 359 1.71E-24 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS40585 9d0aa81623a11b96b18375f87b35ce86 604 PANTHER PTHR23344 366 602 6.6E-65 T 23-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 DC74_RS40585 9d0aa81623a11b96b18375f87b35ce86 604 SUPERFAMILY SSF51695 368 597 7.06E-67 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS40585 9d0aa81623a11b96b18375f87b35ce86 604 Gene3D G3DSA:2.60.120.200 197 359 5.2E-29 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS40585 9d0aa81623a11b96b18375f87b35ce86 604 Gene3D G3DSA:2.60.120.200 3 152 6.5E-27 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS40585 9d0aa81623a11b96b18375f87b35ce86 604 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 4 146 4.1E-25 T 23-04-2016 DC74_RS40585 9d0aa81623a11b96b18375f87b35ce86 604 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 208 360 1.5E-24 T 23-04-2016 DC74_RS40585 9d0aa81623a11b96b18375f87b35ce86 604 SMART SM00560 6 145 9.7E-19 T 23-04-2016 IPR006558 LamG-like jellyroll fold DC74_RS40585 9d0aa81623a11b96b18375f87b35ce86 604 SMART SM00560 225 364 1.1E-16 T 23-04-2016 IPR006558 LamG-like jellyroll fold DC74_RS40585 9d0aa81623a11b96b18375f87b35ce86 604 Gene3D G3DSA:3.20.20.190 369 598 4.4E-67 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS40585 9d0aa81623a11b96b18375f87b35ce86 604 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 373 591 1.8E-39 T 23-04-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 DC74_RS06230 3aba8254d09c0ba0e7108eba3db2a553 370 SUPERFAMILY SSF53822 16 340 1.58E-52 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS06230 3aba8254d09c0ba0e7108eba3db2a553 370 PANTHER PTHR30483:SF6 10 363 7.7E-71 T 23-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 DC74_RS06230 3aba8254d09c0ba0e7108eba3db2a553 370 Gene3D G3DSA:3.40.50.2300 143 291 6.8E-5 T 23-04-2016 DC74_RS06230 3aba8254d09c0ba0e7108eba3db2a553 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 41 57 6.3E-5 T 23-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 DC74_RS06230 3aba8254d09c0ba0e7108eba3db2a553 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 60 78 6.3E-5 T 23-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 DC74_RS06230 3aba8254d09c0ba0e7108eba3db2a553 370 Pfam PF13458 Periplasmic binding protein 17 338 4.6E-38 T 23-04-2016 IPR028081 Leucine-binding protein domain DC74_RS06230 3aba8254d09c0ba0e7108eba3db2a553 370 Gene3D G3DSA:3.40.50.2300 292 337 9.6E-36 T 23-04-2016 DC74_RS06230 3aba8254d09c0ba0e7108eba3db2a553 370 Gene3D G3DSA:3.40.50.2300 14 141 9.6E-36 T 23-04-2016 DC74_RS06230 3aba8254d09c0ba0e7108eba3db2a553 370 PANTHER PTHR30483 10 363 7.7E-71 T 23-04-2016 DC74_RS24610 f87e706d44c09392e735cce9d8f529d2 491 Gene3D G3DSA:3.40.309.10 254 452 2.3E-65 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS24610 f87e706d44c09392e735cce9d8f529d2 491 SUPERFAMILY SSF53720 2 483 9.16E-152 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS24610 f87e706d44c09392e735cce9d8f529d2 491 PANTHER PTHR11699 2 489 1.1E-253 T 23-04-2016 DC74_RS24610 f87e706d44c09392e735cce9d8f529d2 491 PANTHER PTHR11699:SF164 2 489 1.1E-253 T 23-04-2016 DC74_RS24610 f87e706d44c09392e735cce9d8f529d2 491 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS24610 f87e706d44c09392e735cce9d8f529d2 491 Gene3D G3DSA:3.40.605.10 3 253 3.0E-82 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS24610 f87e706d44c09392e735cce9d8f529d2 491 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS24610 f87e706d44c09392e735cce9d8f529d2 491 Pfam PF00171 Aldehyde dehydrogenase family 2 477 1.3E-158 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS06625 15ba10b5cf0696bef0d50df55dcaeefc 463 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 48 399 1.9E-47 T 23-04-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 DC74_RS06625 15ba10b5cf0696bef0d50df55dcaeefc 463 Gene3D G3DSA:3.40.640.10 84 352 2.4E-85 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS06625 15ba10b5cf0696bef0d50df55dcaeefc 463 SUPERFAMILY SSF53383 11 458 2.34E-104 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS06625 15ba10b5cf0696bef0d50df55dcaeefc 463 PANTHER PTHR11999 48 458 3.8E-93 T 23-04-2016 DC74_RS06625 15ba10b5cf0696bef0d50df55dcaeefc 463 Gene3D G3DSA:3.90.1150.10 353 457 5.2E-23 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS09515 9df79ce5f5c43c2dfdf84967f494ec09 622 Pfam PF02618 YceG-like family 308 608 7.3E-62 T 23-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like DC74_RS09515 9df79ce5f5c43c2dfdf84967f494ec09 622 PANTHER PTHR30518 252 621 1.5E-72 T 23-04-2016 DC74_RS09515 9df79ce5f5c43c2dfdf84967f494ec09 622 Gene3D G3DSA:3.30.160.60 584 619 6.9E-4 T 23-04-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 DC74_RS09515 9df79ce5f5c43c2dfdf84967f494ec09 622 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 303 615 6.1E-41 T 23-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like DC74_RS09515 9df79ce5f5c43c2dfdf84967f494ec09 622 PANTHER PTHR30518:SF2 252 621 1.5E-72 T 23-04-2016 DC74_RS16765 087206f361e0c46482ee937a148eaa8d 237 SUPERFAMILY SSF46689 14 79 1.7E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS16765 087206f361e0c46482ee937a148eaa8d 237 PANTHER PTHR30055:SF93 9 138 7.3E-47 T 23-04-2016 DC74_RS16765 087206f361e0c46482ee937a148eaa8d 237 PANTHER PTHR30055 9 138 7.3E-47 T 23-04-2016 DC74_RS16765 087206f361e0c46482ee937a148eaa8d 237 Gene3D G3DSA:1.10.357.10 75 225 2.5E-33 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS16765 087206f361e0c46482ee937a148eaa8d 237 SUPERFAMILY SSF48498 88 227 6.32E-25 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS16765 087206f361e0c46482ee937a148eaa8d 237 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 87 226 1.9E-17 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS16765 087206f361e0c46482ee937a148eaa8d 237 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 70 4.4E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS16765 087206f361e0c46482ee937a148eaa8d 237 Gene3D G3DSA:1.10.10.60 9 74 4.0E-23 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01970 1bfc94d6fdb3eea1a0f905c3a85d3bc1 225 SUPERFAMILY SSF46689 18 97 1.8E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01970 1bfc94d6fdb3eea1a0f905c3a85d3bc1 225 PANTHER PTHR30055 14 212 1.1E-47 T 23-04-2016 DC74_RS01970 1bfc94d6fdb3eea1a0f905c3a85d3bc1 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 71 5.8E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01970 1bfc94d6fdb3eea1a0f905c3a85d3bc1 225 PANTHER PTHR30055:SF10 14 212 1.1E-47 T 23-04-2016 DC74_RS01970 1bfc94d6fdb3eea1a0f905c3a85d3bc1 225 Gene3D G3DSA:1.10.10.60 17 67 3.4E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01970 1bfc94d6fdb3eea1a0f905c3a85d3bc1 225 Gene3D G3DSA:1.10.357.10 69 213 9.6E-21 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS01970 1bfc94d6fdb3eea1a0f905c3a85d3bc1 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 8.4E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01970 1bfc94d6fdb3eea1a0f905c3a85d3bc1 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 8.4E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS20810 33b19b136ef6ab7c11c1381a9ab5db08 372 PANTHER PTHR36174 139 372 1.9E-148 T 23-04-2016 DC74_RS20810 33b19b136ef6ab7c11c1381a9ab5db08 372 PANTHER PTHR36174 1 122 1.9E-148 T 23-04-2016 DC74_RS20810 33b19b136ef6ab7c11c1381a9ab5db08 372 Gene3D G3DSA:3.40.630.30 1 116 1.9E-54 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS20810 33b19b136ef6ab7c11c1381a9ab5db08 372 Gene3D G3DSA:3.40.630.30 148 184 1.9E-54 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS20810 33b19b136ef6ab7c11c1381a9ab5db08 372 PANTHER PTHR36174:SF1 139 372 1.9E-148 T 23-04-2016 DC74_RS20810 33b19b136ef6ab7c11c1381a9ab5db08 372 PANTHER PTHR36174:SF1 1 122 1.9E-148 T 23-04-2016 DC74_RS20810 33b19b136ef6ab7c11c1381a9ab5db08 372 SUPERFAMILY SSF55729 143 194 1.59E-35 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS20810 33b19b136ef6ab7c11c1381a9ab5db08 372 Gene3D G3DSA:3.40.630.30 185 345 2.2E-51 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS20810 33b19b136ef6ab7c11c1381a9ab5db08 372 SUPERFAMILY SSF55729 185 365 5.83E-36 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS20810 33b19b136ef6ab7c11c1381a9ab5db08 372 Pfam PF02388 FemAB family 265 365 5.1E-17 T 23-04-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 DC74_RS20810 33b19b136ef6ab7c11c1381a9ab5db08 372 Pfam PF02388 FemAB family 8 248 3.4E-28 T 23-04-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 DC74_RS20810 33b19b136ef6ab7c11c1381a9ab5db08 372 SUPERFAMILY SSF55729 5 114 1.59E-35 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS17020 2f9ed7125acfb8f9f190ed0bdd3ba037 252 Gene3D G3DSA:3.40.50.980 7 90 5.6E-6 T 23-04-2016 DC74_RS17020 2f9ed7125acfb8f9f190ed0bdd3ba037 252 Pfam PF00501 AMP-binding enzyme 21 90 5.5E-6 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS17020 2f9ed7125acfb8f9f190ed0bdd3ba037 252 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 11 246 2.7E-77 T 23-04-2016 IPR017523 Conserved hypothetical protein CHP03089 DC74_RS17020 2f9ed7125acfb8f9f190ed0bdd3ba037 252 SUPERFAMILY SSF56801 3 249 5.36E-20 T 23-04-2016 DC74_RS13495 7ed35add1832c760c4debaf8812ddf4e 107 ProDom PD031543 GP20 GENE GP17 GP16 60 105 6.0E-4 T 23-04-2016 IPR020286 Protein of unknown function Gp20 DC74_RS12800 55b19d0831f6263bae969f98c8eb7393 405 PIRSF PIRSF010361 1 398 3.3E-70 T 23-04-2016 IPR016570 Uncharacterised conserved protein UCP010361, membrane DC74_RS12800 55b19d0831f6263bae969f98c8eb7393 405 Pfam PF09594 Protein of unknown function (DUF2029) 44 285 2.5E-13 T 23-04-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 DC74_RS23205 e6489be3b4bc5c0b85c5ff3fd49cbb55 341 PANTHER PTHR30146:SF30 2 339 1.8E-107 T 23-04-2016 DC74_RS23205 e6489be3b4bc5c0b85c5ff3fd49cbb55 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 51 1.1E-14 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS23205 e6489be3b4bc5c0b85c5ff3fd49cbb55 341 Gene3D G3DSA:1.10.260.40 4 63 2.0E-23 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS23205 e6489be3b4bc5c0b85c5ff3fd49cbb55 341 PANTHER PTHR30146 2 339 1.8E-107 T 23-04-2016 DC74_RS23205 e6489be3b4bc5c0b85c5ff3fd49cbb55 341 Gene3D G3DSA:3.40.50.2300 64 172 1.1E-33 T 23-04-2016 DC74_RS23205 e6489be3b4bc5c0b85c5ff3fd49cbb55 341 SUPERFAMILY SSF47413 3 62 1.03E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS23205 e6489be3b4bc5c0b85c5ff3fd49cbb55 341 Pfam PF13377 Periplasmic binding protein-like domain 171 337 6.8E-31 T 23-04-2016 DC74_RS23205 e6489be3b4bc5c0b85c5ff3fd49cbb55 341 SUPERFAMILY SSF53822 64 338 2.16E-59 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS23205 e6489be3b4bc5c0b85c5ff3fd49cbb55 341 Gene3D G3DSA:3.40.50.2300 173 339 1.2E-47 T 23-04-2016 DC74_RS23205 e6489be3b4bc5c0b85c5ff3fd49cbb55 341 SMART SM00354 3 74 3.4E-27 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS02595 7426e456cae8eae4fd8229f90a20ea91 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 144 8.6E-9 T 23-04-2016 IPR019587 Polyketide cyclase/dehydrase DC74_RS02595 7426e456cae8eae4fd8229f90a20ea91 147 Gene3D G3DSA:3.30.530.20 6 144 2.6E-13 T 23-04-2016 IPR023393 START-like domain DC74_RS02595 7426e456cae8eae4fd8229f90a20ea91 147 SUPERFAMILY SSF55961 3 144 1.67E-15 T 23-04-2016 DC74_RS34435 4061181827221ecacefed872b5d02a47 603 Gene3D G3DSA:3.40.50.970 66 271 1.2E-28 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS34435 4061181827221ecacefed872b5d02a47 603 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 163 247 4.4E-6 T 23-04-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 DC74_RS34435 4061181827221ecacefed872b5d02a47 603 SUPERFAMILY SSF52518 64 277 6.7E-27 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS06185 58312d062404212c330c47cdb31881ac 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 63 3.1E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS06185 58312d062404212c330c47cdb31881ac 192 PANTHER PTHR30055 5 111 2.1E-14 T 23-04-2016 DC74_RS06185 58312d062404212c330c47cdb31881ac 192 PANTHER PTHR30055:SF36 5 111 2.1E-14 T 23-04-2016 DC74_RS06185 58312d062404212c330c47cdb31881ac 192 SUPERFAMILY SSF46689 11 74 7.83E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06185 58312d062404212c330c47cdb31881ac 192 Gene3D G3DSA:1.10.357.10 8 187 5.6E-28 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS06185 58312d062404212c330c47cdb31881ac 192 SUPERFAMILY SSF48498 83 186 1.45E-6 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS17910 568811041d77ec3e780a4b7f84736aa8 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 20 42 8.5E-8 T 23-04-2016 DC74_RS17910 568811041d77ec3e780a4b7f84736aa8 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 319 8.5E-8 T 23-04-2016 DC74_RS17910 568811041d77ec3e780a4b7f84736aa8 412 Gene3D G3DSA:3.50.50.60 271 343 1.2E-43 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17910 568811041d77ec3e780a4b7f84736aa8 412 Gene3D G3DSA:3.50.50.60 18 131 1.2E-43 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17910 568811041d77ec3e780a4b7f84736aa8 412 SUPERFAMILY SSF51905 130 270 9.07E-27 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17910 568811041d77ec3e780a4b7f84736aa8 412 SUPERFAMILY SSF51905 18 159 9.64E-27 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17910 568811041d77ec3e780a4b7f84736aa8 412 PANTHER PTHR10632:SF2 18 411 1.4E-155 T 23-04-2016 DC74_RS17910 568811041d77ec3e780a4b7f84736aa8 412 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 20 318 1.5E-17 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17910 568811041d77ec3e780a4b7f84736aa8 412 PANTHER PTHR10632 18 411 1.4E-155 T 23-04-2016 DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 Pfam PF13365 Trypsin-like peptidase domain 140 324 1.1E-27 T 23-04-2016 DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 Gene3D G3DSA:2.40.10.10 133 211 2.0E-29 T 23-04-2016 DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 PANTHER PTHR22939 36 254 2.6E-67 T 23-04-2016 DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 PANTHER PTHR22939 296 364 2.6E-67 T 23-04-2016 DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 PRINTS PR00834 HtrA/DegQ protease family signature 295 312 4.3E-26 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 PRINTS PR00834 HtrA/DegQ protease family signature 317 334 4.3E-26 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 PRINTS PR00834 HtrA/DegQ protease family signature 170 190 4.3E-26 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 PRINTS PR00834 HtrA/DegQ protease family signature 149 161 4.3E-26 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 SUPERFAMILY SSF50494 115 252 8.08E-52 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 SUPERFAMILY SSF50494 299 357 8.08E-52 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 Gene3D G3DSA:2.40.10.10 295 364 8.9E-38 T 23-04-2016 DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 Gene3D G3DSA:2.40.10.10 212 245 8.9E-38 T 23-04-2016 DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 PANTHER PTHR22939:SF79 36 254 2.6E-67 T 23-04-2016 DC74_RS23210 ec09b78a981253fc9ad3c9c83eebe444 372 PANTHER PTHR22939:SF79 296 364 2.6E-67 T 23-04-2016 DC74_RS29775 1d06555b4d64f07c7a40ab009efbbbbf 385 SMART SM00474 1 165 4.1E-33 T 23-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 DC74_RS29775 1d06555b4d64f07c7a40ab009efbbbbf 385 Pfam PF00570 HRDC domain 207 271 1.2E-13 T 23-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 DC74_RS29775 1d06555b4d64f07c7a40ab009efbbbbf 385 SUPERFAMILY SSF53098 4 202 1.99E-48 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS29775 1d06555b4d64f07c7a40ab009efbbbbf 385 Gene3D G3DSA:3.30.420.10 63 172 7.4E-6 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS29775 1d06555b4d64f07c7a40ab009efbbbbf 385 Gene3D G3DSA:1.10.150.80 213 261 4.6E-4 T 23-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 DC74_RS29775 1d06555b4d64f07c7a40ab009efbbbbf 385 PANTHER PTHR12124 3 304 6.7E-52 T 23-04-2016 DC74_RS29775 1d06555b4d64f07c7a40ab009efbbbbf 385 Pfam PF01612 3'-5' exonuclease 6 165 9.5E-33 T 23-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 DC74_RS29775 1d06555b4d64f07c7a40ab009efbbbbf 385 SUPERFAMILY SSF47819 185 296 5.01E-26 T 23-04-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 DC74_RS29775 1d06555b4d64f07c7a40ab009efbbbbf 385 SMART SM00341 204 284 1.9E-16 T 23-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 DC74_RS32015 129d7b77049f4d127cee102374e57510 261 PANTHER PTHR33993:SF2 11 261 4.2E-80 T 23-04-2016 DC74_RS32015 129d7b77049f4d127cee102374e57510 261 PANTHER PTHR33993 11 261 4.2E-80 T 23-04-2016 DC74_RS32015 129d7b77049f4d127cee102374e57510 261 SUPERFAMILY SSF54593 13 188 4.23E-20 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS32015 129d7b77049f4d127cee102374e57510 261 Gene3D G3DSA:3.10.180.10 12 129 1.2E-33 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS32015 129d7b77049f4d127cee102374e57510 261 Gene3D G3DSA:3.10.180.10 144 259 1.9E-31 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS32015 129d7b77049f4d127cee102374e57510 261 SUPERFAMILY SSF54593 144 256 1.22E-21 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS32015 129d7b77049f4d127cee102374e57510 261 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 124 1.1E-4 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS13270 a73166ed7fcbd20794d3d0ed07fbbb31 533 PANTHER PTHR22642 1 532 3.4E-121 T 23-04-2016 DC74_RS13270 a73166ed7fcbd20794d3d0ed07fbbb31 533 SUPERFAMILY SSF51556 188 488 1.0E-36 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS13270 a73166ed7fcbd20794d3d0ed07fbbb31 533 SUPERFAMILY SSF51556 55 112 1.0E-36 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS13270 a73166ed7fcbd20794d3d0ed07fbbb31 533 SUPERFAMILY SSF51338 1 56 6.74E-19 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS13270 a73166ed7fcbd20794d3d0ed07fbbb31 533 SUPERFAMILY SSF51338 488 530 6.74E-19 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS13270 a73166ed7fcbd20794d3d0ed07fbbb31 533 Pfam PF07969 Amidohydrolase family 44 527 3.8E-67 T 23-04-2016 IPR013108 Amidohydrolase 3 DC74_RS13270 a73166ed7fcbd20794d3d0ed07fbbb31 533 Gene3D G3DSA:2.30.40.10 1 88 1.4E-14 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS13270 a73166ed7fcbd20794d3d0ed07fbbb31 533 Gene3D G3DSA:2.30.40.10 477 510 6.5E-4 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS13270 a73166ed7fcbd20794d3d0ed07fbbb31 533 PANTHER PTHR22642:SF2 1 532 3.4E-121 T 23-04-2016 DC74_RS13270 a73166ed7fcbd20794d3d0ed07fbbb31 533 Gene3D G3DSA:3.20.20.140 194 476 9.8E-33 T 23-04-2016 DC74_RS07865 a4138b0f8b1864bb84321615e8e41ac8 265 Pfam PF01925 Sulfite exporter TauE/SafE 4 260 3.8E-25 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 DC74_RS07865 a4138b0f8b1864bb84321615e8e41ac8 265 PANTHER PTHR30269 1 262 4.5E-116 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 DC74_RS07865 a4138b0f8b1864bb84321615e8e41ac8 265 PANTHER PTHR30269:SF7 1 262 4.5E-116 T 23-04-2016 DC74_RS03535 020a1d17aab4f9cf6e424920dd298023 203 Pfam PF01464 Transglycosylase SLT domain 60 174 2.5E-14 T 23-04-2016 IPR008258 Transglycosylase SLT domain 1 DC74_RS03535 020a1d17aab4f9cf6e424920dd298023 203 SUPERFAMILY SSF53955 28 188 2.33E-33 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS03535 020a1d17aab4f9cf6e424920dd298023 203 Gene3D G3DSA:1.10.530.10 49 195 6.6E-31 T 23-04-2016 DC74_RS03535 020a1d17aab4f9cf6e424920dd298023 203 PANTHER PTHR21666 36 179 1.0E-14 T 23-04-2016 DC74_RS02155 8f28bb354ee08d9f44099d5575a44ae2 327 Gene3D G3DSA:3.40.50.1100 35 136 3.5E-18 T 23-04-2016 DC74_RS02155 8f28bb354ee08d9f44099d5575a44ae2 327 SUPERFAMILY SSF53686 20 309 5.89E-65 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS02155 8f28bb354ee08d9f44099d5575a44ae2 327 PANTHER PTHR10314:SF109 17 307 8.7E-64 T 23-04-2016 DC74_RS02155 8f28bb354ee08d9f44099d5575a44ae2 327 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 9 307 3.5E-116 T 23-04-2016 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA DC74_RS02155 8f28bb354ee08d9f44099d5575a44ae2 327 Gene3D G3DSA:3.40.50.1100 137 306 8.6E-48 T 23-04-2016 DC74_RS02155 8f28bb354ee08d9f44099d5575a44ae2 327 PANTHER PTHR10314 17 307 8.7E-64 T 23-04-2016 DC74_RS02155 8f28bb354ee08d9f44099d5575a44ae2 327 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 278 1.8E-44 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS08350 1428bd5f1764d99c19d4d65c8ae58ccc 377 Gene3D G3DSA:3.90.1200.10 239 278 2.9E-9 T 23-04-2016 DC74_RS08350 1428bd5f1764d99c19d4d65c8ae58ccc 377 Gene3D G3DSA:3.90.1200.10 120 140 2.9E-9 T 23-04-2016 DC74_RS08350 1428bd5f1764d99c19d4d65c8ae58ccc 377 Pfam PF01636 Phosphotransferase enzyme family 112 301 1.7E-14 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS08350 1428bd5f1764d99c19d4d65c8ae58ccc 377 SUPERFAMILY SSF56112 85 313 1.76E-23 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 412 1.4E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 SMART SM00304 152 206 2.0E-4 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 265 6.9E-14 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 Gene3D G3DSA:1.10.287.130 197 261 7.9E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 SUPERFAMILY SSF47384 191 265 1.49E-14 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 SMART SM00388 207 265 9.5E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 Gene3D G3DSA:3.30.565.10 274 411 6.3E-22 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 Pfam PF00672 HAMP domain 133 202 8.0E-14 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 SUPERFAMILY SSF55874 254 411 1.96E-24 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 SMART SM00387 311 414 6.4E-18 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 6.8E-6 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 411 6.8E-6 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 356 6.8E-6 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 PANTHER PTHR24423 146 427 1.6E-43 T 23-04-2016 DC74_RS16305 c676c2245a7beccbd53b5efaa88d7294 427 PANTHER PTHR24423 32 109 1.6E-43 T 23-04-2016 DC74_RS04705 6a313cc770fcface50a85bb0a1a77809 310 PANTHER PTHR11695:SF294 15 308 1.7E-64 T 23-04-2016 DC74_RS04705 6a313cc770fcface50a85bb0a1a77809 310 SUPERFAMILY SSF50129 1 150 1.23E-39 T 23-04-2016 IPR011032 GroES-like DC74_RS04705 6a313cc770fcface50a85bb0a1a77809 310 SMART SM00829 10 307 3.7E-13 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS04705 6a313cc770fcface50a85bb0a1a77809 310 SUPERFAMILY SSF51735 117 279 8.45E-25 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04705 6a313cc770fcface50a85bb0a1a77809 310 PANTHER PTHR11695 15 308 1.7E-64 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS04705 6a313cc770fcface50a85bb0a1a77809 310 Pfam PF13602 Zinc-binding dehydrogenase 200 307 3.3E-12 T 23-04-2016 DC74_RS04705 6a313cc770fcface50a85bb0a1a77809 310 Gene3D G3DSA:3.40.50.720 151 234 8.5E-10 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04705 6a313cc770fcface50a85bb0a1a77809 310 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 1.2E-8 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS04705 6a313cc770fcface50a85bb0a1a77809 310 Gene3D G3DSA:3.90.180.10 1 150 9.6E-45 T 23-04-2016 IPR011032 GroES-like DC74_RS40285 2761975ff02d77aa3b2de5e2f5de85ee 264 SUPERFAMILY SSF48008 116 256 1.23E-21 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS40285 2761975ff02d77aa3b2de5e2f5de85ee 264 Pfam PF07729 FCD domain 121 247 5.0E-20 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS40285 2761975ff02d77aa3b2de5e2f5de85ee 264 Gene3D G3DSA:1.20.120.530 115 259 1.4E-22 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS40285 2761975ff02d77aa3b2de5e2f5de85ee 264 SUPERFAMILY SSF46785 127 134 4.91E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS40285 2761975ff02d77aa3b2de5e2f5de85ee 264 SUPERFAMILY SSF46785 27 99 4.91E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS40285 2761975ff02d77aa3b2de5e2f5de85ee 264 Gene3D G3DSA:1.10.10.10 28 97 3.7E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS40285 2761975ff02d77aa3b2de5e2f5de85ee 264 Pfam PF00392 Bacterial regulatory proteins, gntR family 34 89 1.1E-20 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40285 2761975ff02d77aa3b2de5e2f5de85ee 264 SMART SM00345 34 95 2.2E-19 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40285 2761975ff02d77aa3b2de5e2f5de85ee 264 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 67 4.4E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40285 2761975ff02d77aa3b2de5e2f5de85ee 264 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 67 83 4.4E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40285 2761975ff02d77aa3b2de5e2f5de85ee 264 PANTHER PTHR11751 34 135 4.4E-23 T 23-04-2016 DC74_RS40285 2761975ff02d77aa3b2de5e2f5de85ee 264 SMART SM00895 119 248 2.3E-16 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS18640 53317073271fee827ac72ec2d683292a 437 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 436 29.942 T 23-04-2016 IPR026593 Protein translocase subunit SecY DC74_RS18640 53317073271fee827ac72ec2d683292a 437 PANTHER PTHR10906 1 437 2.5E-201 T 23-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 SUPERFAMILY SSF103491 2 427 1.02E-127 T 23-04-2016 IPR023201 SecY subunit domain DC74_RS18640 53317073271fee827ac72ec2d683292a 437 ProSitePatterns PS00756 Protein secY signature 2. 176 193 - T 23-04-2016 IPR030659 SecY conserved site DC74_RS18640 53317073271fee827ac72ec2d683292a 437 Pfam PF00344 SecY translocase 73 420 6.4E-118 T 23-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 Gene3D G3DSA:1.10.3370.10 2 437 1.6E-158 T 23-04-2016 IPR023201 SecY subunit domain DC74_RS18640 53317073271fee827ac72ec2d683292a 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 274 293 1.2E-107 T 23-04-2016 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 1.2E-107 T 23-04-2016 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 1.2E-107 T 23-04-2016 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 316 338 1.2E-107 T 23-04-2016 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 1.2E-107 T 23-04-2016 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 1.2E-107 T 23-04-2016 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 371 389 1.2E-107 T 23-04-2016 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 1.2E-107 T 23-04-2016 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 405 423 1.2E-107 T 23-04-2016 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 PANTHER PTHR10906:SF2 1 437 2.5E-201 T 23-04-2016 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 23-04-2016 IPR030659 SecY conserved site DC74_RS18640 53317073271fee827ac72ec2d683292a 437 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 432 3.6E-149 T 23-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 DC74_RS18640 53317073271fee827ac72ec2d683292a 437 PIRSF PIRSF004557 1 437 1.2E-126 T 23-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 DC74_RS32540 204cde08783c55644b745a4b59f64be5 439 SUPERFAMILY SSF55874 326 435 3.58E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32540 204cde08783c55644b745a4b59f64be5 439 PANTHER PTHR24421:SF26 115 439 7.1E-82 T 23-04-2016 DC74_RS32540 204cde08783c55644b745a4b59f64be5 439 PANTHER PTHR24421 115 439 7.1E-82 T 23-04-2016 DC74_RS32540 204cde08783c55644b745a4b59f64be5 439 Pfam PF07730 Histidine kinase 234 299 5.7E-19 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS24290 7626b57d3e7acef5787a4a7ae55f0066 531 SMART SM00857 33 193 4.4E-5 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS24290 7626b57d3e7acef5787a4a7ae55f0066 531 Pfam PF07508 Recombinase 219 311 1.1E-10 T 23-04-2016 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 DC74_RS24290 7626b57d3e7acef5787a4a7ae55f0066 531 Pfam PF00239 Resolvase, N terminal domain 33 193 8.9E-8 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS24290 7626b57d3e7acef5787a4a7ae55f0066 531 PANTHER PTHR30461 33 464 9.8E-24 T 23-04-2016 DC74_RS24290 7626b57d3e7acef5787a4a7ae55f0066 531 SUPERFAMILY SSF53041 33 193 4.19E-8 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS24290 7626b57d3e7acef5787a4a7ae55f0066 531 PANTHER PTHR30461:SF3 33 464 9.8E-24 T 23-04-2016 DC74_RS03405 0761ee12046d4aa3a56d36200b45fb8f 108 SUPERFAMILY SSF55729 1 108 5.41E-16 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS03405 0761ee12046d4aa3a56d36200b45fb8f 108 PANTHER PTHR23091 1 108 1.6E-12 T 23-04-2016 DC74_RS03405 0761ee12046d4aa3a56d36200b45fb8f 108 Gene3D G3DSA:3.40.630.30 1 108 5.7E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS20145 805fe1920aa215f225da4566bf92ef75 1200 PANTHER PTHR23304 45 1199 0.0 T 23-04-2016 DC74_RS20145 805fe1920aa215f225da4566bf92ef75 1200 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 41 1193 0.0 T 23-04-2016 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 DC74_RS20145 805fe1920aa215f225da4566bf92ef75 1200 Pfam PF02514 CobN/Magnesium Chelatase 102 1180 0.0 T 23-04-2016 IPR003672 CobN/magnesium chelatase GO:0009058 DC74_RS20145 805fe1920aa215f225da4566bf92ef75 1200 PANTHER PTHR23304:SF96 45 1199 0.0 T 23-04-2016 DC74_RS03000 53d7436695306b18361f18a9582b0a57 302 Gene3D G3DSA:3.40.366.10 34 92 1.8E-26 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS03000 53d7436695306b18361f18a9582b0a57 302 Gene3D G3DSA:3.40.366.10 159 257 1.8E-26 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS03000 53d7436695306b18361f18a9582b0a57 302 SUPERFAMILY SSF52151 32 98 1.7E-28 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS03000 53d7436695306b18361f18a9582b0a57 302 SUPERFAMILY SSF52151 161 255 1.7E-28 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS03000 53d7436695306b18361f18a9582b0a57 302 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 10 282 4.8E-14 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS03000 53d7436695306b18361f18a9582b0a57 302 SUPERFAMILY SSF55048 96 157 3.4E-6 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS03000 53d7436695306b18361f18a9582b0a57 302 Pfam PF00698 Acyl transferase domain 31 259 1.3E-17 T 23-04-2016 IPR014043 Acyl transferase DC74_RS03000 53d7436695306b18361f18a9582b0a57 302 PANTHER PTHR11712 34 254 7.4E-25 T 23-04-2016 DC74_RS15020 a62e170fb281c68fbdc4377840dff52a 247 PANTHER PTHR30027:SF3 1 247 8.4E-63 T 23-04-2016 DC74_RS15020 a62e170fb281c68fbdc4377840dff52a 247 PIRSF PIRSF015601 3 246 2.2E-48 T 23-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS15020 a62e170fb281c68fbdc4377840dff52a 247 SUPERFAMILY SSF88697 5 70 6.21E-10 T 23-04-2016 IPR015947 PUA-like domain DC74_RS15020 a62e170fb281c68fbdc4377840dff52a 247 SUPERFAMILY SSF75217 77 246 1.26E-46 T 23-04-2016 IPR029028 Alpha/beta knot methyltransferases DC74_RS15020 a62e170fb281c68fbdc4377840dff52a 247 Gene3D G3DSA:3.40.1280.10 4 246 5.6E-71 T 23-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DC74_RS15020 a62e170fb281c68fbdc4377840dff52a 247 PANTHER PTHR30027 1 247 8.4E-63 T 23-04-2016 DC74_RS15020 a62e170fb281c68fbdc4377840dff52a 247 Pfam PF04452 RNA methyltransferase 21 239 3.4E-62 T 23-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS15020 a62e170fb281c68fbdc4377840dff52a 247 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 19 239 1.8E-34 T 23-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS00735 66557e942b6dbc4db75ab139f94feef3 493 PANTHER PTHR11699 5 485 4.4E-177 T 23-04-2016 DC74_RS00735 66557e942b6dbc4db75ab139f94feef3 493 Gene3D G3DSA:3.40.309.10 271 454 1.2E-60 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS00735 66557e942b6dbc4db75ab139f94feef3 493 Gene3D G3DSA:3.40.605.10 11 270 2.5E-79 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS00735 66557e942b6dbc4db75ab139f94feef3 493 Pfam PF00171 Aldehyde dehydrogenase family 18 479 6.8E-149 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS00735 66557e942b6dbc4db75ab139f94feef3 493 SUPERFAMILY SSF53720 7 482 1.7E-145 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS00735 66557e942b6dbc4db75ab139f94feef3 493 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS23025 b0d389f158ed0e05d1934a1dc4681027 494 Gene3D G3DSA:3.40.50.300 313 400 3.5E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23025 b0d389f158ed0e05d1934a1dc4681027 494 Gene3D G3DSA:3.40.50.300 174 213 3.5E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23025 b0d389f158ed0e05d1934a1dc4681027 494 SUPERFAMILY SSF52540 176 406 3.5E-16 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23025 b0d389f158ed0e05d1934a1dc4681027 494 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 311 398 5.0E-12 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 SUPERFAMILY SSF52402 465 583 1.18E-65 T 23-04-2016 DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 SUPERFAMILY SSF52402 230 398 1.18E-65 T 23-04-2016 DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 PANTHER PTHR11772:SF7 2 400 7.3E-213 T 23-04-2016 DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 PANTHER PTHR11772:SF7 454 550 7.3E-213 T 23-04-2016 DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 SUPERFAMILY SSF56235 1 225 1.72E-64 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 Gene3D G3DSA:3.60.20.10 1 224 1.9E-77 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 Gene3D G3DSA:3.40.50.620 225 402 1.8E-75 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 Gene3D G3DSA:3.40.50.620 469 583 1.8E-75 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 PIRSF PIRSF001589 1 615 1.7E-137 T 23-04-2016 DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 Pfam PF00733 Asparagine synthase 241 608 1.1E-89 T 23-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 Pfam PF13537 Glutamine amidotransferase domain 48 169 6.2E-46 T 23-04-2016 IPR017932 Glutamine amidotransferase type 2 domain DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 545 1.5E-147 T 23-04-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|UniPathway: UPA00134 DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 PANTHER PTHR11772 2 400 7.3E-213 T 23-04-2016 DC74_RS10785 faf14911f5ac1731ae3444917d882913 616 PANTHER PTHR11772 454 550 7.3E-213 T 23-04-2016 DC74_RS26420 ed2c6694587bb8d0057a25ba43f3169e 556 PANTHER PTHR11819 18 547 1.3E-215 T 23-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS26420 ed2c6694587bb8d0057a25ba43f3169e 556 Pfam PF00474 Sodium:solute symporter family 56 420 1.1E-18 T 23-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS26420 ed2c6694587bb8d0057a25ba43f3169e 556 PANTHER PTHR11819:SF2 18 547 1.3E-215 T 23-04-2016 DC74_RS11175 bfdb807864d9a4345f0054f7ddf79475 188 Pfam PF13523 Acetyltransferase (GNAT) domain 22 165 3.1E-47 T 23-04-2016 DC74_RS11175 bfdb807864d9a4345f0054f7ddf79475 188 SMART SM01006 19 66 1.1E-14 T 23-04-2016 IPR019432 Siderophore biosynthesis protein, conserved domain DC74_RS11175 bfdb807864d9a4345f0054f7ddf79475 188 SUPERFAMILY SSF55729 11 179 1.61E-40 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS11175 bfdb807864d9a4345f0054f7ddf79475 188 PANTHER PTHR31438 14 183 5.8E-48 T 23-04-2016 DC74_RS11175 bfdb807864d9a4345f0054f7ddf79475 188 Gene3D G3DSA:3.40.630.30 7 185 1.4E-53 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 7.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 7.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 7.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 7.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 7.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 190 0.0085 T 23-04-2016 DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.1E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.1E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.1E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 PANTHER PTHR24322 8 132 1.1E-47 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 PANTHER PTHR24322 150 181 1.1E-47 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 Gene3D G3DSA:3.40.50.720 4 236 2.2E-63 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 SUPERFAMILY SSF51735 3 236 3.33E-61 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38430 542b89a1782eab98e9d30d8f15a695ea 287 Pfam PF00106 short chain dehydrogenase 7 191 1.2E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS26110 5ec8ecda750ace7b59654efd12f15672 578 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 491 1.3E-76 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain DC74_RS26110 5ec8ecda750ace7b59654efd12f15672 578 Gene3D G3DSA:3.90.76.10 62 237 7.8E-33 T 23-04-2016 DC74_RS26110 5ec8ecda750ace7b59654efd12f15672 578 PANTHER PTHR30290 5 566 5.4E-93 T 23-04-2016 DC74_RS26110 5ec8ecda750ace7b59654efd12f15672 578 Gene3D G3DSA:3.10.105.10 326 548 5.5E-43 T 23-04-2016 DC74_RS26110 5ec8ecda750ace7b59654efd12f15672 578 SUPERFAMILY SSF53850 44 567 2.35E-99 T 23-04-2016 DC74_RS26110 5ec8ecda750ace7b59654efd12f15672 578 PIRSF PIRSF002741 14 577 2.6E-67 T 23-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DC74_RS00645 b4a268e455e2e223dba344e5a38dea10 513 ProSitePatterns PS00336 Beta-lactamase class-C active site. 43 50 - T 23-04-2016 IPR001586 Beta-lactamase, class-C active site GO:0008800|GO:0017001|GO:0030288 KEGG: 00311+3.5.2.6 DC74_RS00645 b4a268e455e2e223dba344e5a38dea10 513 PANTHER PTHR22935 5 329 8.5E-68 T 23-04-2016 DC74_RS00645 b4a268e455e2e223dba344e5a38dea10 513 Pfam PF00144 Beta-lactamase 7 316 6.3E-64 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS00645 b4a268e455e2e223dba344e5a38dea10 513 SUPERFAMILY SSF56601 6 319 3.52E-80 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS00645 b4a268e455e2e223dba344e5a38dea10 513 Gene3D G3DSA:3.40.710.10 5 327 4.2E-76 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS27070 6ef723423aa81a4a5d3503cb49efb4f9 408 PANTHER PTHR24421 56 356 2.4E-61 T 23-04-2016 DC74_RS27070 6ef723423aa81a4a5d3503cb49efb4f9 408 Pfam PF07730 Histidine kinase 190 253 1.9E-14 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS27070 6ef723423aa81a4a5d3503cb49efb4f9 408 SUPERFAMILY SSF55874 298 346 9.03E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27070 6ef723423aa81a4a5d3503cb49efb4f9 408 PANTHER PTHR24421:SF26 56 356 2.4E-61 T 23-04-2016 DC74_RS11970 4dcaab32bad7d31ba3a6a58d86c15fb1 293 PANTHER PTHR30136 12 289 1.3E-15 T 23-04-2016 DC74_RS11970 4dcaab32bad7d31ba3a6a58d86c15fb1 293 SUPERFAMILY SSF55781 108 283 1.77E-16 T 23-04-2016 IPR029016 GAF domain-like DC74_RS11970 4dcaab32bad7d31ba3a6a58d86c15fb1 293 Gene3D G3DSA:3.30.450.40 112 279 3.8E-19 T 23-04-2016 IPR029016 GAF domain-like DC74_RS11970 4dcaab32bad7d31ba3a6a58d86c15fb1 293 Pfam PF01614 Bacterial transcriptional regulator 173 254 6.3E-10 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS11970 4dcaab32bad7d31ba3a6a58d86c15fb1 293 PANTHER PTHR30136:SF14 12 289 1.3E-15 T 23-04-2016 DC74_RS11970 4dcaab32bad7d31ba3a6a58d86c15fb1 293 Gene3D G3DSA:1.10.10.10 24 96 1.9E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05580 2d9f0f8b2cc1e75b2d4fd73fdb4461a7 287 PANTHER PTHR30269 1 250 3.8E-56 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 DC74_RS05580 2d9f0f8b2cc1e75b2d4fd73fdb4461a7 287 Pfam PF01925 Sulfite exporter TauE/SafE 6 239 1.1E-52 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 DC74_RS05580 2d9f0f8b2cc1e75b2d4fd73fdb4461a7 287 PANTHER PTHR30269:SF14 1 250 3.8E-56 T 23-04-2016 DC74_RS36995 850d08c746545207be2ef3a4a4a1cdf6 294 Gene3D G3DSA:1.10.1740.10 5 76 6.8E-13 T 23-04-2016 DC74_RS36995 850d08c746545207be2ef3a4a4a1cdf6 294 SUPERFAMILY SSF88659 108 168 2.06E-8 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS36995 850d08c746545207be2ef3a4a4a1cdf6 294 Pfam PF04542 Sigma-70 region 2 11 74 1.2E-13 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS36995 850d08c746545207be2ef3a4a4a1cdf6 294 SUPERFAMILY SSF88946 4 84 2.59E-13 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS36995 850d08c746545207be2ef3a4a4a1cdf6 294 Pfam PF08281 Sigma-70, region 4 116 166 2.7E-7 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS36995 850d08c746545207be2ef3a4a4a1cdf6 294 PANTHER PTHR30173 3 290 1.2E-94 T 23-04-2016 DC74_RS36995 850d08c746545207be2ef3a4a4a1cdf6 294 SUPERFAMILY SSF54427 181 290 7.84E-14 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS36995 850d08c746545207be2ef3a4a4a1cdf6 294 Gene3D G3DSA:3.10.450.50 176 289 2.3E-10 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS36995 850d08c746545207be2ef3a4a4a1cdf6 294 Gene3D G3DSA:1.10.10.10 115 168 1.0E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36995 850d08c746545207be2ef3a4a4a1cdf6 294 PANTHER PTHR30173:SF11 3 290 1.2E-94 T 23-04-2016 DC74_RS36995 850d08c746545207be2ef3a4a4a1cdf6 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 168 1.6E-13 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28825 ed0f422f605e949720b144abefdc94ce 247 Gene3D G3DSA:3.40.50.2300 1 121 4.9E-35 T 23-04-2016 DC74_RS28825 ed0f422f605e949720b144abefdc94ce 247 Pfam PF00072 Response regulator receiver domain 4 114 2.2E-23 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS28825 ed0f422f605e949720b144abefdc94ce 247 PANTHER PTHR26402:SF518 1 236 7.6E-101 T 23-04-2016 DC74_RS28825 ed0f422f605e949720b144abefdc94ce 247 SMART SM00448 1 114 8.4E-37 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS28825 ed0f422f605e949720b144abefdc94ce 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 231 9.7E-25 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS28825 ed0f422f605e949720b144abefdc94ce 247 SUPERFAMILY SSF52172 1 193 1.11E-35 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS28825 ed0f422f605e949720b144abefdc94ce 247 SMART SM00862 159 231 3.5E-25 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS28825 ed0f422f605e949720b144abefdc94ce 247 PANTHER PTHR26402 1 236 7.6E-101 T 23-04-2016 DC74_RS28825 ed0f422f605e949720b144abefdc94ce 247 Gene3D G3DSA:1.10.10.10 139 234 8.5E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05405 c652e25765ed5f878531263f9075047f 247 SMART SM00895 109 238 1.6E-13 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS05405 c652e25765ed5f878531263f9075047f 247 Gene3D G3DSA:1.10.10.10 16 87 1.4E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05405 c652e25765ed5f878531263f9075047f 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 79 5.6E-10 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS05405 c652e25765ed5f878531263f9075047f 247 SUPERFAMILY SSF48008 108 243 4.71E-17 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS05405 c652e25765ed5f878531263f9075047f 247 SMART SM00345 23 84 0.0013 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS05405 c652e25765ed5f878531263f9075047f 247 Pfam PF07729 FCD domain 109 237 5.0E-18 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS05405 c652e25765ed5f878531263f9075047f 247 Gene3D G3DSA:1.20.120.530 108 244 8.2E-17 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS05405 c652e25765ed5f878531263f9075047f 247 SUPERFAMILY SSF46785 16 103 3.69E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14815 749a7e496b38e65dfb8f2f4d67dd883c 485 SUPERFAMILY SSF103473 247 464 2.22E-70 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS14815 749a7e496b38e65dfb8f2f4d67dd883c 485 SUPERFAMILY SSF103473 4 199 2.22E-70 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS14815 749a7e496b38e65dfb8f2f4d67dd883c 485 Gene3D G3DSA:1.20.1250.20 6 197 1.6E-36 T 23-04-2016 DC74_RS14815 749a7e496b38e65dfb8f2f4d67dd883c 485 Pfam PF07690 Major Facilitator Superfamily 17 408 1.4E-60 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS14815 749a7e496b38e65dfb8f2f4d67dd883c 485 PANTHER PTHR23501:SF91 3 467 6.5E-197 T 23-04-2016 DC74_RS14815 749a7e496b38e65dfb8f2f4d67dd883c 485 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 416 7.5E-89 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS14815 749a7e496b38e65dfb8f2f4d67dd883c 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 75 97 2.2E-8 T 23-04-2016 DC74_RS14815 749a7e496b38e65dfb8f2f4d67dd883c 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 2.2E-8 T 23-04-2016 DC74_RS14815 749a7e496b38e65dfb8f2f4d67dd883c 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 2.2E-8 T 23-04-2016 DC74_RS14815 749a7e496b38e65dfb8f2f4d67dd883c 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 2.2E-8 T 23-04-2016 DC74_RS14815 749a7e496b38e65dfb8f2f4d67dd883c 485 Gene3D G3DSA:1.20.1250.20 267 455 1.3E-17 T 23-04-2016 DC74_RS14815 749a7e496b38e65dfb8f2f4d67dd883c 485 PANTHER PTHR23501 3 467 6.5E-197 T 23-04-2016 DC74_RS37510 d6f31e15ae4646dcbf5eeeffcfa16976 180 PANTHER PTHR40763:SF2 13 180 3.0E-44 T 23-04-2016 DC74_RS37510 d6f31e15ae4646dcbf5eeeffcfa16976 180 PANTHER PTHR40763 13 180 3.0E-44 T 23-04-2016 DC74_RS37510 d6f31e15ae4646dcbf5eeeffcfa16976 180 Pfam PF08044 Domain of unknown function (DUF1707) 13 62 9.1E-17 T 23-04-2016 IPR012551 Protein of unknown function DUF1707 DC74_RS27520 ad8d1bff2af7486108ee6610facd4d9b 210 Pfam PF03458 UPF0126 domain 90 164 2.2E-18 T 23-04-2016 IPR005115 Uncharacterised domain UPF0126 DC74_RS27520 ad8d1bff2af7486108ee6610facd4d9b 210 Pfam PF03458 UPF0126 domain 4 75 1.4E-15 T 23-04-2016 IPR005115 Uncharacterised domain UPF0126 DC74_RS27520 ad8d1bff2af7486108ee6610facd4d9b 210 PANTHER PTHR30506 1 209 4.7E-54 T 23-04-2016 DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 3.0E-56 T 23-04-2016 DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 PANTHER PTHR24322 154 186 7.2E-54 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 SUPERFAMILY SSF51735 4 249 1.18E-75 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 PANTHER PTHR24322:SF562 154 186 7.2E-54 T 23-04-2016 DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 Gene3D G3DSA:3.40.50.720 3 249 3.8E-76 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.5E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.5E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.5E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.5E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.5E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.5E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 PANTHER PTHR24322:SF562 9 138 7.2E-54 T 23-04-2016 DC74_RS03230 e77d8a751cdf6600ae97c172cc061110 256 PANTHER PTHR24322 9 138 7.2E-54 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS33900 ee07884a8993199fd1da9d41ed661fd8 263 Gene3D G3DSA:1.10.3720.10 57 260 2.2E-42 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS33900 ee07884a8993199fd1da9d41ed661fd8 263 SUPERFAMILY SSF161098 56 245 2.09E-37 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS33900 ee07884a8993199fd1da9d41ed661fd8 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 259 8.9E-19 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS33900 ee07884a8993199fd1da9d41ed661fd8 263 PANTHER PTHR30614 1 263 1.1E-63 T 23-04-2016 DC74_RS33900 ee07884a8993199fd1da9d41ed661fd8 263 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 56 151 5.8E-19 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 DC74_RS22005 2b9aa499222b9ec2e75271c6f8be66fb 154 SUPERFAMILY SSF89095 3 152 6.28E-36 T 23-04-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 DC74_RS22005 2b9aa499222b9ec2e75271c6f8be66fb 154 PANTHER PTHR28055:SF1 1 154 1.1E-45 T 23-04-2016 DC74_RS22005 2b9aa499222b9ec2e75271c6f8be66fb 154 Gene3D G3DSA:1.10.10.410 94 153 2.9E-22 T 23-04-2016 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal DC74_RS22005 2b9aa499222b9ec2e75271c6f8be66fb 154 Gene3D G3DSA:1.10.1510.10 3 93 3.9E-25 T 23-04-2016 DC74_RS22005 2b9aa499222b9ec2e75271c6f8be66fb 154 PANTHER PTHR28055 1 154 1.1E-45 T 23-04-2016 DC74_RS22005 2b9aa499222b9ec2e75271c6f8be66fb 154 Pfam PF09424 Yqey-like protein 5 152 1.4E-45 T 23-04-2016 IPR019004 Uncharacterised domain YOR215C, mitochondrial DC74_RS00700 b3397225c4597668e9c9e2c066fce928 288 SUPERFAMILY SSF51679 5 275 1.03E-25 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS00700 b3397225c4597668e9c9e2c066fce928 288 Gene3D G3DSA:3.20.20.30 16 279 9.4E-13 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS00700 b3397225c4597668e9c9e2c066fce928 288 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 3 284 2.5E-88 T 23-04-2016 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted DC74_RS32400 aef43b050bfdacef57d5413e731fb70b 379 SUPERFAMILY SSF53756 1 378 2.26E-64 T 23-04-2016 DC74_RS32400 aef43b050bfdacef57d5413e731fb70b 379 Gene3D G3DSA:3.40.50.2000 1 217 1.4E-15 T 23-04-2016 DC74_RS32400 aef43b050bfdacef57d5413e731fb70b 379 Gene3D G3DSA:3.40.50.2000 218 360 8.4E-17 T 23-04-2016 DC74_RS32400 aef43b050bfdacef57d5413e731fb70b 379 Pfam PF06722 Protein of unknown function (DUF1205) 173 266 7.0E-20 T 23-04-2016 IPR010610 Domain of unknown function DUF1205 DC74_RS17370 c03cb83edcc5c90c18c579496867149c 352 SUPERFAMILY SSF53955 40 122 7.87E-27 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS17370 c03cb83edcc5c90c18c579496867149c 352 Gene3D G3DSA:3.10.350.10 298 345 2.6E-5 T 23-04-2016 IPR018392 LysM domain DC74_RS17370 c03cb83edcc5c90c18c579496867149c 352 Gene3D G3DSA:1.10.530.10 19 122 1.6E-37 T 23-04-2016 DC74_RS17370 c03cb83edcc5c90c18c579496867149c 352 Pfam PF06737 Transglycosylase-like domain 40 116 6.6E-30 T 23-04-2016 IPR010618 Transglycosylase-like DC74_RS13440 2ac7883f331c632dea455a6655b323b7 356 SUPERFAMILY SSF56601 12 326 6.42E-66 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS13440 2ac7883f331c632dea455a6655b323b7 356 Gene3D G3DSA:3.40.710.10 10 328 5.0E-62 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS13440 2ac7883f331c632dea455a6655b323b7 356 Pfam PF00144 Beta-lactamase 10 333 6.0E-53 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS13440 2ac7883f331c632dea455a6655b323b7 356 PANTHER PTHR22935 56 327 1.1E-51 T 23-04-2016 DC74_RS04225 fde995001ac615a43cef785d64d9d772 509 PANTHER PTHR30330 19 493 7.8E-178 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 DC74_RS04225 fde995001ac615a43cef785d64d9d772 509 PANTHER PTHR30330:SF3 19 493 7.8E-178 T 23-04-2016 DC74_RS04225 fde995001ac615a43cef785d64d9d772 509 PRINTS PR00175 Sodium/alanine symporter signature 223 241 3.4E-46 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 DC74_RS04225 fde995001ac615a43cef785d64d9d772 509 PRINTS PR00175 Sodium/alanine symporter signature 116 138 3.4E-46 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 DC74_RS04225 fde995001ac615a43cef785d64d9d772 509 PRINTS PR00175 Sodium/alanine symporter signature 396 418 3.4E-46 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 DC74_RS04225 fde995001ac615a43cef785d64d9d772 509 PRINTS PR00175 Sodium/alanine symporter signature 341 359 3.4E-46 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 DC74_RS04225 fde995001ac615a43cef785d64d9d772 509 PRINTS PR00175 Sodium/alanine symporter signature 251 270 3.4E-46 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 DC74_RS04225 fde995001ac615a43cef785d64d9d772 509 PRINTS PR00175 Sodium/alanine symporter signature 457 477 3.4E-46 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 DC74_RS04225 fde995001ac615a43cef785d64d9d772 509 TIGRFAM TIGR00835 agcS: amino acid carrier protein 44 486 5.7E-115 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 DC74_RS04225 fde995001ac615a43cef785d64d9d772 509 Pfam PF01235 Sodium:alanine symporter family 79 494 1.0E-126 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 DC74_RS13245 089c854562cd8e4b4f7e3e71856f6540 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 298 3.4E-18 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS13245 089c854562cd8e4b4f7e3e71856f6540 311 SUPERFAMILY SSF161098 70 296 4.45E-61 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS13245 089c854562cd8e4b4f7e3e71856f6540 311 PANTHER PTHR32243 8 309 3.3E-91 T 23-04-2016 DC74_RS13245 089c854562cd8e4b4f7e3e71856f6540 311 PANTHER PTHR32243:SF40 8 309 3.3E-91 T 23-04-2016 DC74_RS13245 089c854562cd8e4b4f7e3e71856f6540 311 Gene3D G3DSA:1.10.3720.10 76 307 1.5E-63 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS25975 3f86366f1403cb1f9ac444678c3fe021 229 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 43 200 1.3E-32 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS25975 3f86366f1403cb1f9ac444678c3fe021 229 PANTHER PTHR30173 17 206 6.2E-70 T 23-04-2016 DC74_RS25975 3f86366f1403cb1f9ac444678c3fe021 229 Pfam PF04542 Sigma-70 region 2 47 112 4.8E-21 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS25975 3f86366f1403cb1f9ac444678c3fe021 229 SUPERFAMILY SSF88659 139 201 2.06E-17 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS25975 3f86366f1403cb1f9ac444678c3fe021 229 Gene3D G3DSA:1.10.1740.10 41 135 7.1E-27 T 23-04-2016 DC74_RS25975 3f86366f1403cb1f9ac444678c3fe021 229 PANTHER PTHR30173:SF18 17 206 6.2E-70 T 23-04-2016 DC74_RS25975 3f86366f1403cb1f9ac444678c3fe021 229 Pfam PF08281 Sigma-70, region 4 146 196 1.1E-16 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS25975 3f86366f1403cb1f9ac444678c3fe021 229 Gene3D G3DSA:1.10.10.10 137 202 2.4E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25975 3f86366f1403cb1f9ac444678c3fe021 229 SUPERFAMILY SSF88946 42 122 5.89E-24 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS19690 b505d7ce2a086314eae70b7705f6ec18 519 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 23 474 2.0E-156 T 23-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 DC74_RS19690 b505d7ce2a086314eae70b7705f6ec18 519 Pfam PF00156 Phosphoribosyl transferase domain 297 403 1.1E-7 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 DC74_RS19690 b505d7ce2a086314eae70b7705f6ec18 519 PIRSF PIRSF000485 19 485 1.5E-161 T 23-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 DC74_RS19690 b505d7ce2a086314eae70b7705f6ec18 519 SUPERFAMILY SSF56235 23 286 4.37E-65 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS19690 b505d7ce2a086314eae70b7705f6ec18 519 PANTHER PTHR11907:SF0 20 487 8.8E-231 T 23-04-2016 DC74_RS19690 b505d7ce2a086314eae70b7705f6ec18 519 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 22 475 46.751 T 23-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 DC74_RS19690 b505d7ce2a086314eae70b7705f6ec18 519 Pfam PF13522 Glutamine amidotransferase domain 83 227 2.0E-15 T 23-04-2016 DC74_RS19690 b505d7ce2a086314eae70b7705f6ec18 519 SUPERFAMILY SSF53271 268 483 1.19E-67 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS19690 b505d7ce2a086314eae70b7705f6ec18 519 PANTHER PTHR11907 20 487 8.8E-231 T 23-04-2016 DC74_RS19690 b505d7ce2a086314eae70b7705f6ec18 519 Gene3D G3DSA:3.60.20.10 23 274 1.3E-68 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS19690 b505d7ce2a086314eae70b7705f6ec18 519 Gene3D G3DSA:3.40.50.2020 290 456 2.5E-44 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS29995 d6351dd0ce666d3034e180cdd6b5aea3 295 Pfam PF01636 Phosphotransferase enzyme family 36 240 1.9E-15 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS29995 d6351dd0ce666d3034e180cdd6b5aea3 295 Gene3D G3DSA:3.90.1200.10 103 219 2.4E-11 T 23-04-2016 DC74_RS29995 d6351dd0ce666d3034e180cdd6b5aea3 295 SUPERFAMILY SSF56112 6 266 1.43E-30 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS38370 5c6215b56a1b23de34cb1cc9053b6a71 334 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 27 314 2.4E-45 T 23-04-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 DC74_RS38370 5c6215b56a1b23de34cb1cc9053b6a71 334 SUPERFAMILY SSF51197 25 316 4.58E-71 T 23-04-2016 DC74_RS38370 5c6215b56a1b23de34cb1cc9053b6a71 334 PANTHER PTHR10696:SF27 27 316 2.6E-47 T 23-04-2016 DC74_RS38370 5c6215b56a1b23de34cb1cc9053b6a71 334 Gene3D G3DSA:3.60.130.10 197 321 1.4E-60 T 23-04-2016 DC74_RS38370 5c6215b56a1b23de34cb1cc9053b6a71 334 Gene3D G3DSA:3.60.130.10 18 165 1.4E-60 T 23-04-2016 DC74_RS38370 5c6215b56a1b23de34cb1cc9053b6a71 334 PANTHER PTHR10696 27 316 2.6E-47 T 23-04-2016 DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 1.8E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 1.8E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 1.8E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 Gene3D G3DSA:1.10.10.10 149 208 5.5E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 191 1.2E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 Pfam PF00072 Response regulator receiver domain 2 105 2.1E-16 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 Gene3D G3DSA:3.40.50.2300 2 148 7.7E-27 T 23-04-2016 DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 SMART SM00448 1 117 4.1E-6 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 PANTHER PTHR26402:SF582 1 205 2.0E-83 T 23-04-2016 DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 PANTHER PTHR26402 1 205 2.0E-83 T 23-04-2016 DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 SMART SM00421 144 207 7.7E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 SUPERFAMILY SSF52172 2 136 1.71E-20 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS07930 2894d63594181096081ddc1228ecb8d6 212 SUPERFAMILY SSF46894 132 192 4.42E-15 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 SUPERFAMILY SSF54665 149 298 9.94E-40 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 36 44 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Gene3D G3DSA:3.90.1170.50 145 267 2.4E-39 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Gene3D G3DSA:3.30.365.10 333 437 5.2E-38 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 SMART SM01008 167 279 4.8E-47 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Gene3D G3DSA:3.10.20.30 2 71 4.9E-23 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 56 1.9E-4 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Gene3D G3DSA:3.30.365.10 758 903 2.7E-55 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Gene3D G3DSA:3.30.365.10 514 603 2.7E-55 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Gene3D G3DSA:1.10.150.120 72 144 2.3E-26 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 PANTHER PTHR11908:SF96 729 907 3.9E-298 T 23-04-2016 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 PANTHER PTHR11908:SF96 151 704 3.9E-298 T 23-04-2016 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Gene3D G3DSA:3.30.365.10 604 751 2.9E-33 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 SUPERFAMILY SSF54292 3 86 1.05E-19 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 SUPERFAMILY SSF47741 81 144 1.96E-23 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Gene3D G3DSA:3.30.365.10 439 512 5.7E-41 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Gene3D G3DSA:3.30.365.10 268 332 5.7E-41 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Pfam PF01799 [2Fe-2S] binding domain 70 138 4.5E-25 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 309 841 2.7E-152 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 SUPERFAMILY SSF56003 273 901 1.44E-172 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 167 279 2.3E-26 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 PANTHER PTHR11908 729 907 3.9E-298 T 23-04-2016 DC74_RS06270 eef93d6b41ecba1f93fd27142e86c1a7 919 PANTHER PTHR11908 151 704 3.9E-298 T 23-04-2016 DC74_RS13315 99f87ccf4952d49b0a955a70879d9ff2 422 PANTHER PTHR23501 1 379 8.4E-137 T 23-04-2016 DC74_RS13315 99f87ccf4952d49b0a955a70879d9ff2 422 Gene3D G3DSA:1.20.1250.20 198 376 3.9E-14 T 23-04-2016 DC74_RS13315 99f87ccf4952d49b0a955a70879d9ff2 422 PANTHER PTHR23501:SF4 1 379 8.4E-137 T 23-04-2016 DC74_RS13315 99f87ccf4952d49b0a955a70879d9ff2 422 Gene3D G3DSA:1.20.1250.20 5 184 1.2E-27 T 23-04-2016 DC74_RS13315 99f87ccf4952d49b0a955a70879d9ff2 422 SUPERFAMILY SSF103473 3 379 3.27E-58 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS13315 99f87ccf4952d49b0a955a70879d9ff2 422 Pfam PF07690 Major Facilitator Superfamily 8 339 2.4E-43 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS19350 e124de7975684ce2cdbd0238cdc13110 189 PANTHER PTHR30055 3 185 3.3E-19 T 23-04-2016 DC74_RS19350 e124de7975684ce2cdbd0238cdc13110 189 Gene3D G3DSA:1.10.357.10 64 187 3.8E-33 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS19350 e124de7975684ce2cdbd0238cdc13110 189 Gene3D G3DSA:1.10.10.60 4 62 7.5E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS19350 e124de7975684ce2cdbd0238cdc13110 189 PANTHER PTHR30055:SF53 3 185 3.3E-19 T 23-04-2016 DC74_RS19350 e124de7975684ce2cdbd0238cdc13110 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 6.1E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS19350 e124de7975684ce2cdbd0238cdc13110 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 6.1E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS19350 e124de7975684ce2cdbd0238cdc13110 189 SUPERFAMILY SSF48498 78 186 1.07E-23 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS19350 e124de7975684ce2cdbd0238cdc13110 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 2.9E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS19350 e124de7975684ce2cdbd0238cdc13110 189 SUPERFAMILY SSF46689 4 66 4.05E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 324 431 2.2E-14 T 23-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 293 308 9.0E-5 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 143 157 9.0E-5 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 SUPERFAMILY SSF55957 433 540 1.03E-13 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 218 309 8.0E-23 T 23-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 Gene3D G3DSA:3.40.120.10 305 438 3.2E-30 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 PANTHER PTHR22573 27 553 3.5E-190 T 23-04-2016 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 144 153 - T 23-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 Gene3D G3DSA:3.40.120.10 21 211 1.9E-58 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 504 527 1.1E-6 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 SUPERFAMILY SSF53738 206 310 1.14E-19 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 Gene3D G3DSA:3.30.310.50 461 546 5.7E-17 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 SUPERFAMILY SSF53738 301 436 1.84E-23 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 PANTHER PTHR22573:SF54 27 553 3.5E-190 T 23-04-2016 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 48 185 1.6E-39 T 23-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 SUPERFAMILY SSF53738 38 205 1.61E-41 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS25055 b260da9e38e4efc62ada6710cdd86291 560 Gene3D G3DSA:3.40.120.10 226 304 3.0E-19 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS04065 a9261ebf5aa4f063f0acd3f8631b285a 271 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 221 232 - T 23-04-2016 IPR033116 Serine proteases, trypsin family, serine active site DC74_RS04065 a9261ebf5aa4f063f0acd3f8631b285a 271 Pfam PF00089 Trypsin 47 260 6.8E-62 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS04065 a9261ebf5aa4f063f0acd3f8631b285a 271 PANTHER PTHR24276 10 260 1.0E-103 T 23-04-2016 DC74_RS04065 a9261ebf5aa4f063f0acd3f8631b285a 271 Gene3D G3DSA:2.40.10.10 81 268 8.9E-58 T 23-04-2016 DC74_RS04065 a9261ebf5aa4f063f0acd3f8631b285a 271 SUPERFAMILY SSF50494 16 261 3.75E-78 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS04065 a9261ebf5aa4f063f0acd3f8631b285a 271 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 73 88 4.7E-14 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS04065 a9261ebf5aa4f063f0acd3f8631b285a 271 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 128 142 4.7E-14 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS04065 a9261ebf5aa4f063f0acd3f8631b285a 271 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 220 232 4.7E-14 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS04065 a9261ebf5aa4f063f0acd3f8631b285a 271 Gene3D G3DSA:2.40.10.10 47 80 1.3E-16 T 23-04-2016 DC74_RS04065 a9261ebf5aa4f063f0acd3f8631b285a 271 SMART SM00020 46 268 9.3E-76 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS04065 a9261ebf5aa4f063f0acd3f8631b285a 271 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 83 88 - T 23-04-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 DC74_RS39845 264ccf0da76153e3a58e9ea36e7872ce 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 85 4.5E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39845 264ccf0da76153e3a58e9ea36e7872ce 234 SUPERFAMILY SSF48498 120 216 1.82E-5 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS39845 264ccf0da76153e3a58e9ea36e7872ce 234 SUPERFAMILY SSF46689 30 108 4.62E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39845 264ccf0da76153e3a58e9ea36e7872ce 234 Gene3D G3DSA:1.10.357.10 20 204 4.3E-28 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS39845 264ccf0da76153e3a58e9ea36e7872ce 234 PANTHER PTHR30055 25 234 5.2E-19 T 23-04-2016 DC74_RS39845 264ccf0da76153e3a58e9ea36e7872ce 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 52 4.1E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39845 264ccf0da76153e3a58e9ea36e7872ce 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 60 83 4.1E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 Gene3D G3DSA:3.30.70.1430 575 654 1.4E-5 T 23-04-2016 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 Gene3D G3DSA:3.30.70.1430 41 130 2.4E-26 T 23-04-2016 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 Gene3D G3DSA:3.30.2090.10 185 272 3.5E-12 T 23-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 PANTHER PTHR32063 1 1039 0.0 T 23-04-2016 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 Pfam PF00873 AcrB/AcrD/AcrF family 5 1021 5.5E-225 T 23-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 SUPERFAMILY SSF82693 571 656 5.18E-5 T 23-04-2016 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 SUPERFAMILY SSF82693 275 330 3.14E-16 T 23-04-2016 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 SUPERFAMILY SSF82693 41 130 1.23E-23 T 23-04-2016 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 SUPERFAMILY SSF82714 725 799 2.22E-5 T 23-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 SUPERFAMILY SSF82714 184 271 7.32E-11 T 23-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 SUPERFAMILY SSF82866 799 1025 7.46E-50 T 23-04-2016 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 Gene3D G3DSA:1.10.3850.10 279 498 1.9E-58 T 23-04-2016 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 Gene3D G3DSA:1.10.3850.10 807 1022 7.7E-58 T 23-04-2016 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 8.4E-42 T 23-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 PRINTS PR00702 Acriflavin resistance protein family signature 337 360 8.4E-42 T 23-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 PRINTS PR00702 Acriflavin resistance protein family signature 364 385 8.4E-42 T 23-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 8.4E-42 T 23-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 PRINTS PR00702 Acriflavin resistance protein family signature 392 416 8.4E-42 T 23-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 8.4E-42 T 23-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 SUPERFAMILY SSF82866 301 498 8.24E-43 T 23-04-2016 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 PANTHER PTHR32063:SF0 1 1039 0.0 T 23-04-2016 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 SUPERFAMILY SSF82693 134 181 3.14E-16 T 23-04-2016 DC74_RS12985 7fc043dc21877a9135b5fde9ab16c22a 1058 Gene3D G3DSA:3.30.2090.10 726 803 4.7E-6 T 23-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains DC74_RS07800 ae04ef3d6b9c4d9b7bc4d94ad45d70db 304 SUPERFAMILY SSF53850 88 296 3.33E-35 T 23-04-2016 DC74_RS07800 ae04ef3d6b9c4d9b7bc4d94ad45d70db 304 SUPERFAMILY SSF46785 1 112 2.47E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07800 ae04ef3d6b9c4d9b7bc4d94ad45d70db 304 Gene3D G3DSA:1.10.10.10 1 82 7.9E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07800 ae04ef3d6b9c4d9b7bc4d94ad45d70db 304 PANTHER PTHR30346:SF2 1 294 7.0E-85 T 23-04-2016 DC74_RS07800 ae04ef3d6b9c4d9b7bc4d94ad45d70db 304 Gene3D G3DSA:3.40.190.10 199 265 3.2E-18 T 23-04-2016 DC74_RS07800 ae04ef3d6b9c4d9b7bc4d94ad45d70db 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.9E-17 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS07800 ae04ef3d6b9c4d9b7bc4d94ad45d70db 304 Pfam PF03466 LysR substrate binding domain 87 291 1.3E-36 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS07800 ae04ef3d6b9c4d9b7bc4d94ad45d70db 304 Gene3D G3DSA:3.40.190.10 83 198 6.4E-26 T 23-04-2016 DC74_RS07800 ae04ef3d6b9c4d9b7bc4d94ad45d70db 304 PANTHER PTHR30346 1 294 7.0E-85 T 23-04-2016 DC74_RS17480 7de9bf96628b4f4146c08c1045faaa6f 460 SUPERFAMILY SSF55874 357 449 3.24E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17480 7de9bf96628b4f4146c08c1045faaa6f 460 PANTHER PTHR24421 30 250 1.8E-87 T 23-04-2016 DC74_RS17480 7de9bf96628b4f4146c08c1045faaa6f 460 PANTHER PTHR24421:SF26 303 450 1.8E-87 T 23-04-2016 DC74_RS17480 7de9bf96628b4f4146c08c1045faaa6f 460 Pfam PF07730 Histidine kinase 184 249 7.9E-17 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS17480 7de9bf96628b4f4146c08c1045faaa6f 460 PANTHER PTHR24421 303 450 1.8E-87 T 23-04-2016 DC74_RS17480 7de9bf96628b4f4146c08c1045faaa6f 460 PANTHER PTHR24421:SF26 30 250 1.8E-87 T 23-04-2016 DC74_RS03690 d86485eeef4c0d718ddd18796df69b21 132 PANTHER PTHR21366 3 132 4.3E-22 T 23-04-2016 DC74_RS03690 d86485eeef4c0d718ddd18796df69b21 132 SUPERFAMILY SSF54593 3 121 1.48E-24 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS03690 d86485eeef4c0d718ddd18796df69b21 132 Gene3D G3DSA:3.10.180.10 2 121 1.2E-31 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS03690 d86485eeef4c0d718ddd18796df69b21 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 118 1.0E-11 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS03690 d86485eeef4c0d718ddd18796df69b21 132 PANTHER PTHR21366:SF13 3 132 4.3E-22 T 23-04-2016 DC74_RS06210 d31c2464b56c20082bbcab6d2ea1858c 538 SMART SM00220 15 264 1.6E-43 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS06210 d31c2464b56c20082bbcab6d2ea1858c 538 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS06210 d31c2464b56c20082bbcab6d2ea1858c 538 PANTHER PTHR24362:SF247 13 323 6.8E-86 T 23-04-2016 DC74_RS06210 d31c2464b56c20082bbcab6d2ea1858c 538 SUPERFAMILY SSF56112 12 282 7.66E-66 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS06210 d31c2464b56c20082bbcab6d2ea1858c 538 Gene3D G3DSA:1.10.510.10 98 262 1.9E-45 T 23-04-2016 DC74_RS06210 d31c2464b56c20082bbcab6d2ea1858c 538 Gene3D G3DSA:3.30.200.20 8 88 1.0E-11 T 23-04-2016 DC74_RS06210 d31c2464b56c20082bbcab6d2ea1858c 538 Pfam PF00069 Protein kinase domain 16 260 6.8E-41 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS06210 d31c2464b56c20082bbcab6d2ea1858c 538 PANTHER PTHR24362 13 323 6.8E-86 T 23-04-2016 DC74_RS06210 d31c2464b56c20082bbcab6d2ea1858c 538 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS34240 f3e43a1df341f85e742266b86f7954a7 295 Gene3D G3DSA:1.10.800.10 19 281 1.2E-74 T 23-04-2016 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 DC74_RS34240 f3e43a1df341f85e742266b86f7954a7 295 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 20 277 1.9E-57 T 23-04-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 DC74_RS34240 f3e43a1df341f85e742266b86f7954a7 295 PANTHER PTHR11473:SF24 21 278 1.1E-63 T 23-04-2016 DC74_RS34240 f3e43a1df341f85e742266b86f7954a7 295 SUPERFAMILY SSF56534 19 284 9.16E-72 T 23-04-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 DC74_RS34240 f3e43a1df341f85e742266b86f7954a7 295 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 215 233 1.2E-9 T 23-04-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 DC74_RS34240 f3e43a1df341f85e742266b86f7954a7 295 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 110 132 1.2E-9 T 23-04-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 DC74_RS34240 f3e43a1df341f85e742266b86f7954a7 295 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 23 42 1.2E-9 T 23-04-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 DC74_RS34240 f3e43a1df341f85e742266b86f7954a7 295 PANTHER PTHR11473 21 278 1.1E-63 T 23-04-2016 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 DC74_RS21340 79bab1d7ce2c5255a4ce72382b31767c 296 SUPERFAMILY SSF56747 16 213 3.73E-32 T 23-04-2016 DC74_RS21340 79bab1d7ce2c5255a4ce72382b31767c 296 SMART SM00943 20 206 1.1E-41 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal DC74_RS21340 79bab1d7ce2c5255a4ce72382b31767c 296 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 20 203 4.4E-39 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal DC74_RS21340 79bab1d7ce2c5255a4ce72382b31767c 296 SMART SM00942 237 296 3.7E-5 T 23-04-2016 IPR014820 Primase, C-terminal 1 DC74_RS08090 ff8cd320079e990454579a19e14ef787 201 Pfam PF13411 MerR HTH family regulatory protein 47 113 1.4E-14 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS08090 ff8cd320079e990454579a19e14ef787 201 Gene3D G3DSA:1.10.1660.10 49 122 1.1E-13 T 23-04-2016 DC74_RS08090 ff8cd320079e990454579a19e14ef787 201 SMART SM00422 43 115 1.5E-17 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS08090 ff8cd320079e990454579a19e14ef787 201 PANTHER PTHR30204:SF3 35 131 1.3E-54 T 23-04-2016 DC74_RS08090 ff8cd320079e990454579a19e14ef787 201 PANTHER PTHR30204 35 131 1.3E-54 T 23-04-2016 DC74_RS08090 ff8cd320079e990454579a19e14ef787 201 SUPERFAMILY SSF46955 47 131 1.28E-14 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS38885 eeffc0936ed1267ae0e42abed1935175 352 SUPERFAMILY SSF48576 48 350 2.04E-29 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS38885 eeffc0936ed1267ae0e42abed1935175 352 Gene3D G3DSA:1.10.600.10 36 347 4.1E-52 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS06040 1513551ef62d7d01423f46a1683b7644 399 SUPERFAMILY SSF88713 70 115 4.73E-26 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS06040 1513551ef62d7d01423f46a1683b7644 399 SUPERFAMILY SSF88713 145 379 4.73E-26 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS06040 1513551ef62d7d01423f46a1683b7644 399 Gene3D G3DSA:3.20.20.370 69 378 2.5E-10 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS23200 83d07c2fff72aa13ed9bd54eb5cb97c6 274 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 1.3E-28 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS23200 83d07c2fff72aa13ed9bd54eb5cb97c6 274 SUPERFAMILY SSF46894 122 221 8.68E-31 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS23200 83d07c2fff72aa13ed9bd54eb5cb97c6 274 SMART SM00862 145 219 2.2E-30 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS23200 83d07c2fff72aa13ed9bd54eb5cb97c6 274 PANTHER PTHR26402:SF506 32 222 2.3E-68 T 23-04-2016 DC74_RS23200 83d07c2fff72aa13ed9bd54eb5cb97c6 274 PANTHER PTHR26402 32 222 2.3E-68 T 23-04-2016 DC74_RS23200 83d07c2fff72aa13ed9bd54eb5cb97c6 274 Gene3D G3DSA:1.10.10.10 123 222 8.0E-37 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17010 819ac336698399d6dc6f5cd120ea5a82 360 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 306 333 4.5E-4 T 23-04-2016 IPR001451 Hexapeptide repeat DC74_RS17010 819ac336698399d6dc6f5cd120ea5a82 360 Gene3D G3DSA:3.90.550.10 2 238 6.3E-63 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS17010 819ac336698399d6dc6f5cd120ea5a82 360 SUPERFAMILY SSF53448 4 242 3.67E-66 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS17010 819ac336698399d6dc6f5cd120ea5a82 360 SUPERFAMILY SSF53448 279 328 3.67E-66 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS17010 819ac336698399d6dc6f5cd120ea5a82 360 PANTHER PTHR22572:SF15 3 354 6.5E-105 T 23-04-2016 DC74_RS17010 819ac336698399d6dc6f5cd120ea5a82 360 Gene3D G3DSA:2.160.10.10 258 354 8.5E-17 T 23-04-2016 DC74_RS17010 819ac336698399d6dc6f5cd120ea5a82 360 PANTHER PTHR22572 3 354 6.5E-105 T 23-04-2016 DC74_RS17010 819ac336698399d6dc6f5cd120ea5a82 360 Pfam PF00483 Nucleotidyl transferase 4 236 5.5E-44 T 23-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 DC74_RS17525 6af97c9ef50dc470678962212aa59c20 285 PANTHER PTHR10108:SF808 1 251 3.5E-85 T 23-04-2016 DC74_RS17525 6af97c9ef50dc470678962212aa59c20 285 Pfam PF13649 Methyltransferase domain 42 137 1.6E-16 T 23-04-2016 DC74_RS17525 6af97c9ef50dc470678962212aa59c20 285 Gene3D G3DSA:1.10.150.290 195 252 5.3E-26 T 23-04-2016 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 DC74_RS17525 6af97c9ef50dc470678962212aa59c20 285 Gene3D G3DSA:3.40.50.150 9 190 6.0E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS17525 6af97c9ef50dc470678962212aa59c20 285 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 5 271 44.351 T 23-04-2016 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 DC74_RS17525 6af97c9ef50dc470678962212aa59c20 285 SUPERFAMILY SSF53335 6 271 6.08E-35 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS17525 6af97c9ef50dc470678962212aa59c20 285 PANTHER PTHR10108 1 251 3.5E-85 T 23-04-2016 DC74_RS33725 b9b55e01e96d47d40bc37fc3c7d0cd70 403 Gene3D G3DSA:3.40.640.10 50 279 3.8E-68 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS33725 b9b55e01e96d47d40bc37fc3c7d0cd70 403 PANTHER PTHR11751 8 398 1.0E-185 T 23-04-2016 DC74_RS33725 b9b55e01e96d47d40bc37fc3c7d0cd70 403 PANTHER PTHR11751:SF303 8 398 1.0E-185 T 23-04-2016 DC74_RS33725 b9b55e01e96d47d40bc37fc3c7d0cd70 403 Gene3D G3DSA:3.90.1150.10 280 402 5.0E-40 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS33725 b9b55e01e96d47d40bc37fc3c7d0cd70 403 SUPERFAMILY SSF53383 5 400 7.85E-95 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS33725 b9b55e01e96d47d40bc37fc3c7d0cd70 403 Pfam PF00155 Aminotransferase class I and II 34 394 2.3E-49 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS00960 5fa090c4e261880a89280be6b01440fd 309 SUPERFAMILY SSF50129 1 141 1.0E-32 T 23-04-2016 IPR011032 GroES-like DC74_RS00960 5fa090c4e261880a89280be6b01440fd 309 SUPERFAMILY SSF51735 115 242 1.31E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00960 5fa090c4e261880a89280be6b01440fd 309 PANTHER PTHR11695:SF294 15 308 7.6E-89 T 23-04-2016 DC74_RS00960 5fa090c4e261880a89280be6b01440fd 309 Gene3D G3DSA:3.40.50.720 149 234 8.2E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00960 5fa090c4e261880a89280be6b01440fd 309 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 143 164 - T 23-04-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 DC74_RS00960 5fa090c4e261880a89280be6b01440fd 309 SMART SM00829 10 307 8.2E-40 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS00960 5fa090c4e261880a89280be6b01440fd 309 PANTHER PTHR11695 15 308 7.6E-89 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS00960 5fa090c4e261880a89280be6b01440fd 309 Gene3D G3DSA:3.90.180.10 1 148 7.9E-38 T 23-04-2016 IPR011032 GroES-like DC74_RS00960 5fa090c4e261880a89280be6b01440fd 309 Pfam PF13602 Zinc-binding dehydrogenase 186 307 3.5E-29 T 23-04-2016 DC74_RS17920 6fb659eb31acc6e968752e8f437f02b8 417 Gene3D G3DSA:3.30.70.360 192 310 1.3E-34 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS17920 6fb659eb31acc6e968752e8f437f02b8 417 SUPERFAMILY SSF55031 195 302 1.44E-26 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS17920 6fb659eb31acc6e968752e8f437f02b8 417 Pfam PF07687 Peptidase dimerisation domain 196 292 5.7E-12 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS17920 6fb659eb31acc6e968752e8f437f02b8 417 PANTHER PTHR11014:SF89 20 401 8.9E-120 T 23-04-2016 DC74_RS17920 6fb659eb31acc6e968752e8f437f02b8 417 PIRSF PIRSF005962 8 415 1.9E-98 T 23-04-2016 IPR017439 Amidohydrolase GO:0016787 DC74_RS17920 6fb659eb31acc6e968752e8f437f02b8 417 SUPERFAMILY SSF53187 311 413 1.2E-75 T 23-04-2016 DC74_RS17920 6fb659eb31acc6e968752e8f437f02b8 417 SUPERFAMILY SSF53187 12 208 1.2E-75 T 23-04-2016 DC74_RS17920 6fb659eb31acc6e968752e8f437f02b8 417 PANTHER PTHR11014 20 401 8.9E-120 T 23-04-2016 DC74_RS17920 6fb659eb31acc6e968752e8f437f02b8 417 Gene3D G3DSA:3.40.630.10 10 189 2.0E-84 T 23-04-2016 DC74_RS17920 6fb659eb31acc6e968752e8f437f02b8 417 Gene3D G3DSA:3.40.630.10 311 412 2.0E-84 T 23-04-2016 DC74_RS17920 6fb659eb31acc6e968752e8f437f02b8 417 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 24 351 3.9E-86 T 23-04-2016 IPR017439 Amidohydrolase GO:0016787 DC74_RS17920 6fb659eb31acc6e968752e8f437f02b8 417 Pfam PF01546 Peptidase family M20/M25/M40 80 363 1.3E-22 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS01125 44449451adcc27f2da73cf004b2b4059 192 SUPERFAMILY SSF46689 5 79 1.75E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01125 44449451adcc27f2da73cf004b2b4059 192 PANTHER PTHR30055 2 186 1.7E-49 T 23-04-2016 DC74_RS01125 44449451adcc27f2da73cf004b2b4059 192 Gene3D G3DSA:1.10.357.10 60 184 8.7E-12 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS01125 44449451adcc27f2da73cf004b2b4059 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 6.7E-16 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01125 44449451adcc27f2da73cf004b2b4059 192 PANTHER PTHR30055:SF54 2 186 1.7E-49 T 23-04-2016 DC74_RS01125 44449451adcc27f2da73cf004b2b4059 192 Gene3D G3DSA:1.10.10.60 3 59 5.7E-21 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01125 44449451adcc27f2da73cf004b2b4059 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 9.4E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01125 44449451adcc27f2da73cf004b2b4059 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 9.4E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS14990 a74fbbdd5fe8c4556af154fc49aa06c8 435 PANTHER PTHR13794:SF56 1 423 7.2E-171 T 23-04-2016 DC74_RS14990 a74fbbdd5fe8c4556af154fc49aa06c8 435 PANTHER PTHR13794 1 423 7.2E-171 T 23-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 DC74_RS14990 a74fbbdd5fe8c4556af154fc49aa06c8 435 Gene3D G3DSA:3.20.20.120 149 389 1.1E-71 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS14990 a74fbbdd5fe8c4556af154fc49aa06c8 435 SUPERFAMILY SSF54826 10 146 5.39E-21 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS14990 a74fbbdd5fe8c4556af154fc49aa06c8 435 Gene3D G3DSA:3.30.390.10 7 148 2.6E-32 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS14990 a74fbbdd5fe8c4556af154fc49aa06c8 435 Pfam PF13378 Enolase C-terminal domain-like 185 395 1.8E-51 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS14990 a74fbbdd5fe8c4556af154fc49aa06c8 435 SMART SM00922 182 276 2.7E-20 T 23-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DC74_RS14990 a74fbbdd5fe8c4556af154fc49aa06c8 435 SUPERFAMILY SSF51604 146 401 6.16E-70 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS05925 dfe1fbaf5a59e7f2d2252d184126eefb 245 Gene3D G3DSA:3.40.50.2300 14 138 9.4E-40 T 23-04-2016 DC74_RS05925 dfe1fbaf5a59e7f2d2252d184126eefb 245 Gene3D G3DSA:1.10.10.10 143 242 7.5E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05925 dfe1fbaf5a59e7f2d2252d184126eefb 245 SMART SM00448 19 130 4.0E-40 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS05925 dfe1fbaf5a59e7f2d2252d184126eefb 245 PANTHER PTHR26402 19 245 7.9E-97 T 23-04-2016 DC74_RS05925 dfe1fbaf5a59e7f2d2252d184126eefb 245 PANTHER PTHR26402:SF316 19 245 7.9E-97 T 23-04-2016 DC74_RS05925 dfe1fbaf5a59e7f2d2252d184126eefb 245 SUPERFAMILY SSF52172 17 197 4.98E-40 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS05925 dfe1fbaf5a59e7f2d2252d184126eefb 245 Pfam PF00072 Response regulator receiver domain 21 130 5.1E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS05925 dfe1fbaf5a59e7f2d2252d184126eefb 245 SMART SM00862 166 240 2.7E-27 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS05925 dfe1fbaf5a59e7f2d2252d184126eefb 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 169 240 5.7E-25 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 Gene3D G3DSA:1.25.40.10 792 848 1.3E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 Pfam PF00196 Bacterial regulatory proteins, luxR family 878 927 6.1E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 Gene3D G3DSA:1.25.40.10 615 772 8.1E-8 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 SUPERFAMILY SSF48452 657 843 6.12E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 Gene3D G3DSA:3.40.50.300 112 173 5.8E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 Gene3D G3DSA:3.40.50.300 3 64 5.8E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 SUPERFAMILY SSF46894 874 938 1.33E-13 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 878 892 2.4E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 892 908 2.4E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 908 920 2.4E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 Gene3D G3DSA:1.10.10.10 877 929 8.1E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 Pfam PF13191 AAA ATPase domain 2 159 3.4E-19 T 23-04-2016 DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 ProSitePatterns PS00622 LuxR-type HTH domain signature. 892 919 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 SMART SM00421 875 932 1.3E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 SUPERFAMILY SSF52540 127 243 7.83E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32630 fb4e2b4ab6906dc93f695848d10d24b4 947 SUPERFAMILY SSF52540 3 83 7.83E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19255 0017276751ec7ce2f6a2352ddc015b7f 484 SUPERFAMILY SSF50475 3 318 1.02E-114 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS19255 0017276751ec7ce2f6a2352ddc015b7f 484 PANTHER PTHR30108 1 484 2.8E-223 T 23-04-2016 DC74_RS19255 0017276751ec7ce2f6a2352ddc015b7f 484 Gene3D G3DSA:3.40.1670.10 333 448 1.7E-38 T 23-04-2016 DC74_RS19255 0017276751ec7ce2f6a2352ddc015b7f 484 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 449 5.0E-139 T 23-04-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 DC74_RS19255 0017276751ec7ce2f6a2352ddc015b7f 484 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 424 5.6E-158 T 23-04-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 DC74_RS19255 0017276751ec7ce2f6a2352ddc015b7f 484 Gene3D G3DSA:1.20.5.570 449 484 1.4E-6 T 23-04-2016 DC74_RS19255 0017276751ec7ce2f6a2352ddc015b7f 484 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 9 441 1.4E-196 T 23-04-2016 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 DC74_RS19255 0017276751ec7ce2f6a2352ddc015b7f 484 SUPERFAMILY SSF143968 319 484 9.29E-55 T 23-04-2016 DC74_RS19255 0017276751ec7ce2f6a2352ddc015b7f 484 PANTHER PTHR30108:SF1 1 484 2.8E-223 T 23-04-2016 DC74_RS29890 7c4cf8ce202cdaed179adee014ed7a0a 362 PANTHER PTHR30572 222 361 7.1E-24 T 23-04-2016 DC74_RS29890 7c4cf8ce202cdaed179adee014ed7a0a 362 Pfam PF02687 FtsX-like permease family 247 354 1.4E-12 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS29890 7c4cf8ce202cdaed179adee014ed7a0a 362 PANTHER PTHR30572:SF11 222 361 7.1E-24 T 23-04-2016 DC74_RS04425 a6b598cf33f094eedb096f63f24c23fb 157 Pfam PF13577 SnoaL-like domain 10 138 2.1E-19 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS04425 a6b598cf33f094eedb096f63f24c23fb 157 SUPERFAMILY SSF54427 8 148 3.37E-28 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS04425 a6b598cf33f094eedb096f63f24c23fb 157 Gene3D G3DSA:3.10.450.50 9 148 2.3E-23 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS04890 63ff1fc1454732fc677fb93ed7e77f4a 328 SUPERFAMILY SSF53474 63 325 5.83E-59 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS04890 63ff1fc1454732fc677fb93ed7e77f4a 328 Gene3D G3DSA:3.40.50.1820 20 325 8.7E-76 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS04890 63ff1fc1454732fc677fb93ed7e77f4a 328 PANTHER PTHR23024:SF128 70 316 2.3E-74 T 23-04-2016 DC74_RS04890 63ff1fc1454732fc677fb93ed7e77f4a 328 PANTHER PTHR23024 70 316 2.3E-74 T 23-04-2016 DC74_RS04890 63ff1fc1454732fc677fb93ed7e77f4a 328 Pfam PF07859 alpha/beta hydrolase fold 93 301 3.4E-61 T 23-04-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 DC74_RS18410 c11f45333fa504569689030d42095c65 495 Gene3D G3DSA:1.10.510.10 274 374 6.5E-18 T 23-04-2016 DC74_RS18410 c11f45333fa504569689030d42095c65 495 Gene3D G3DSA:1.10.510.10 178 220 6.5E-18 T 23-04-2016 DC74_RS18410 c11f45333fa504569689030d42095c65 495 PANTHER PTHR22983 298 418 1.2E-29 T 23-04-2016 DC74_RS18410 c11f45333fa504569689030d42095c65 495 Gene3D G3DSA:3.30.200.20 114 177 2.3E-8 T 23-04-2016 DC74_RS18410 c11f45333fa504569689030d42095c65 495 PANTHER PTHR22983:SF13 298 418 1.2E-29 T 23-04-2016 DC74_RS18410 c11f45333fa504569689030d42095c65 495 Pfam PF07714 Protein tyrosine kinase 116 206 7.0E-5 T 23-04-2016 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain GO:0004672|GO:0006468 DC74_RS18410 c11f45333fa504569689030d42095c65 495 SUPERFAMILY SSF56112 109 213 3.37E-28 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS18410 c11f45333fa504569689030d42095c65 495 SUPERFAMILY SSF56112 273 380 3.37E-28 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS18410 c11f45333fa504569689030d42095c65 495 SMART SM00220 38 377 2.4E-9 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS11670 6f6688d3e445e5acc082f73be27ca732 296 SUPERFAMILY SSF53335 61 287 9.47E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS11670 6f6688d3e445e5acc082f73be27ca732 296 Gene3D G3DSA:3.40.50.150 68 292 7.7E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS11670 6f6688d3e445e5acc082f73be27ca732 296 PANTHER PTHR10108 62 261 3.5E-23 T 23-04-2016 DC74_RS11670 6f6688d3e445e5acc082f73be27ca732 296 Pfam PF08241 Methyltransferase domain 97 197 1.9E-18 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS03795 96431c95087da9731d559a6974b2e3b8 193 SUPERFAMILY SSF55729 10 140 1.59E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS03795 96431c95087da9731d559a6974b2e3b8 193 Pfam PF13527 Acetyltransferase (GNAT) domain 16 135 2.9E-9 T 23-04-2016 DC74_RS03795 96431c95087da9731d559a6974b2e3b8 193 Gene3D G3DSA:3.40.630.30 14 144 1.2E-15 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS23455 7bfeb795081b8937513ce000f4945fb2 191 PANTHER PTHR32097 1 191 1.8E-92 T 23-04-2016 DC74_RS23455 7bfeb795081b8937513ce000f4945fb2 191 Pfam PF02342 TerD domain 1 187 5.3E-84 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS23455 7bfeb795081b8937513ce000f4945fb2 191 Gene3D G3DSA:2.60.60.30 18 185 2.2E-72 T 23-04-2016 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 PANTHER PTHR10992 219 330 1.2E-51 T 23-04-2016 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 PANTHER PTHR10992 177 198 1.2E-51 T 23-04-2016 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 PANTHER PTHR10992 12 137 1.2E-51 T 23-04-2016 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 PANTHER PTHR10992:SF877 219 330 1.2E-51 T 23-04-2016 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 PANTHER PTHR10992:SF877 177 198 1.2E-51 T 23-04-2016 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 SUPERFAMILY SSF53474 223 330 6.26E-57 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 SUPERFAMILY SSF53474 8 192 6.26E-57 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 Pfam PF00561 alpha/beta hydrolase fold 24 316 5.2E-25 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 PRINTS PR00412 Epoxide hydrolase signature 30 48 1.8E-15 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 PRINTS PR00412 Epoxide hydrolase signature 96 109 1.8E-15 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 PRINTS PR00412 Epoxide hydrolase signature 110 123 1.8E-15 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 PRINTS PR00412 Epoxide hydrolase signature 50 65 1.8E-15 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 PRINTS PR00412 Epoxide hydrolase signature 270 286 1.8E-15 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 PANTHER PTHR10992:SF877 12 137 1.2E-51 T 23-04-2016 DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 Gene3D G3DSA:3.40.50.1820 8 190 9.4E-65 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02305 ecdea79921e3a1eecf50a2fd2da21257 334 Gene3D G3DSA:3.40.50.1820 223 330 9.4E-65 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31745 cff236b866dabd8fd8fda9bb51b181d5 284 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 87 108 - T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS31745 cff236b866dabd8fd8fda9bb51b181d5 284 PANTHER PTHR15362:SF2 17 176 9.9E-20 T 23-04-2016 DC74_RS31745 cff236b866dabd8fd8fda9bb51b181d5 284 PANTHER PTHR15362 17 176 9.9E-20 T 23-04-2016 DC74_RS31745 cff236b866dabd8fd8fda9bb51b181d5 284 Pfam PF01066 CDP-alcohol phosphatidyltransferase 29 108 2.1E-11 T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS31745 cff236b866dabd8fd8fda9bb51b181d5 284 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 34 206 1.7E-33 T 23-04-2016 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 DC74_RS35405 3c850d6b962afaa89415571475f7b054 389 Pfam PF00155 Aminotransferase class I and II 42 379 4.5E-55 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS35405 3c850d6b962afaa89415571475f7b054 389 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 237 246 - T 23-04-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 DC74_RS35405 3c850d6b962afaa89415571475f7b054 389 Gene3D G3DSA:3.40.640.10 60 273 1.5E-76 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS35405 3c850d6b962afaa89415571475f7b054 389 PANTHER PTHR13693:SF53 40 379 8.4E-138 T 23-04-2016 DC74_RS35405 3c850d6b962afaa89415571475f7b054 389 Gene3D G3DSA:3.90.1150.10 274 380 8.0E-15 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS35405 3c850d6b962afaa89415571475f7b054 389 PANTHER PTHR13693 40 379 8.4E-138 T 23-04-2016 DC74_RS35405 3c850d6b962afaa89415571475f7b054 389 SUPERFAMILY SSF53383 17 382 1.0E-91 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS30890 fccf94e25edc8297bca4fb39815565f0 348 PANTHER PTHR30213:SF2 4 348 2.4E-105 T 23-04-2016 DC74_RS30890 fccf94e25edc8297bca4fb39815565f0 348 Pfam PF03631 Virulence factor BrkB 48 302 9.6E-45 T 23-04-2016 IPR017039 Virulence factor BrkB DC74_RS30890 fccf94e25edc8297bca4fb39815565f0 348 PIRSF PIRSF035875 22 324 3.2E-46 T 23-04-2016 IPR017039 Virulence factor BrkB DC74_RS30890 fccf94e25edc8297bca4fb39815565f0 348 PANTHER PTHR30213 4 348 2.4E-105 T 23-04-2016 DC74_RS16350 4c425523e331134b4c7681de7d491acc 77 Pfam PF00367 phosphotransferase system, EIIB 7 39 1.1E-13 T 23-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 DC74_RS16350 4c425523e331134b4c7681de7d491acc 77 SUPERFAMILY SSF55604 5 76 9.02E-22 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 DC74_RS16350 4c425523e331134b4c7681de7d491acc 77 PANTHER PTHR30009:SF4 4 77 7.7E-24 T 23-04-2016 DC74_RS16350 4c425523e331134b4c7681de7d491acc 77 Gene3D G3DSA:3.30.1360.60 3 77 8.1E-28 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 DC74_RS16350 4c425523e331134b4c7681de7d491acc 77 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 3 63 2.2E-17 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 DC74_RS16350 4c425523e331134b4c7681de7d491acc 77 PANTHER PTHR30009 4 77 7.7E-24 T 23-04-2016 DC74_RS03725 740e3e1c5fd14b9d6d7e809644e7ab63 129 PANTHER PTHR33495 7 121 3.0E-26 T 23-04-2016 DC74_RS03725 740e3e1c5fd14b9d6d7e809644e7ab63 129 Pfam PF13466 STAS domain 25 100 5.9E-16 T 23-04-2016 IPR002645 STAS domain DC74_RS03725 740e3e1c5fd14b9d6d7e809644e7ab63 129 SUPERFAMILY SSF52091 14 114 3.73E-24 T 23-04-2016 IPR002645 STAS domain DC74_RS03725 740e3e1c5fd14b9d6d7e809644e7ab63 129 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 15 111 5.8E-22 T 23-04-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 DC74_RS03725 740e3e1c5fd14b9d6d7e809644e7ab63 129 PANTHER PTHR33495:SF3 7 121 3.0E-26 T 23-04-2016 DC74_RS03725 740e3e1c5fd14b9d6d7e809644e7ab63 129 Gene3D G3DSA:3.30.750.24 14 117 7.0E-29 T 23-04-2016 IPR002645 STAS domain DC74_RS08355 dcd60c5c65bb87fb06c6eb3d3f2ab30b 670 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 306 435 7.6E-21 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS08355 dcd60c5c65bb87fb06c6eb3d3f2ab30b 670 PANTHER PTHR30417 16 667 1.4E-219 T 23-04-2016 DC74_RS08355 dcd60c5c65bb87fb06c6eb3d3f2ab30b 670 SMART SM00644 297 434 8.9E-43 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS08355 dcd60c5c65bb87fb06c6eb3d3f2ab30b 670 SUPERFAMILY SSF55846 294 446 3.01E-38 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS08355 dcd60c5c65bb87fb06c6eb3d3f2ab30b 670 SUPERFAMILY SSF53955 31 99 1.5E-6 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS08355 dcd60c5c65bb87fb06c6eb3d3f2ab30b 670 Gene3D G3DSA:1.10.530.10 50 114 6.5E-8 T 23-04-2016 DC74_RS08355 dcd60c5c65bb87fb06c6eb3d3f2ab30b 670 Gene3D G3DSA:1.10.530.10 158 200 6.5E-8 T 23-04-2016 DC74_RS08355 dcd60c5c65bb87fb06c6eb3d3f2ab30b 670 PANTHER PTHR30417:SF1 16 667 1.4E-219 T 23-04-2016 DC74_RS08355 dcd60c5c65bb87fb06c6eb3d3f2ab30b 670 Gene3D G3DSA:3.40.80.10 294 446 1.0E-37 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS21520 b8d00e75d6bf86066ad4b5bdf5c99898 414 Gene3D G3DSA:3.40.50.200 86 409 4.6E-65 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS21520 b8d00e75d6bf86066ad4b5bdf5c99898 414 PRINTS PR00723 Subtilisin serine protease family (S8) signature 103 122 1.0E-5 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS21520 b8d00e75d6bf86066ad4b5bdf5c99898 414 PRINTS PR00723 Subtilisin serine protease family (S8) signature 338 354 1.0E-5 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS21520 b8d00e75d6bf86066ad4b5bdf5c99898 414 SUPERFAMILY SSF52743 85 412 3.27E-43 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS21520 b8d00e75d6bf86066ad4b5bdf5c99898 414 PANTHER PTHR14218 89 407 6.5E-20 T 23-04-2016 DC74_RS21520 b8d00e75d6bf86066ad4b5bdf5c99898 414 Pfam PF00082 Subtilase family 185 354 1.1E-4 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS21520 b8d00e75d6bf86066ad4b5bdf5c99898 414 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 339 349 - T 23-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site DC74_RS21520 b8d00e75d6bf86066ad4b5bdf5c99898 414 PANTHER PTHR14218:SF15 89 407 6.5E-20 T 23-04-2016 DC74_RS38045 1376248f2ec3793065949e81464f40c4 286 SUPERFAMILY SSF161098 13 286 3.01E-75 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38045 1376248f2ec3793065949e81464f40c4 286 PANTHER PTHR32243 10 286 4.7E-121 T 23-04-2016 DC74_RS38045 1376248f2ec3793065949e81464f40c4 286 Gene3D G3DSA:1.10.3720.10 13 273 6.8E-70 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38045 1376248f2ec3793065949e81464f40c4 286 PANTHER PTHR32243:SF42 10 286 4.7E-121 T 23-04-2016 DC74_RS38045 1376248f2ec3793065949e81464f40c4 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 277 3.4E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS06515 d9f0c9745d3dce298b5c5767b82c0096 483 SUPERFAMILY SSF56601 31 350 3.91E-83 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS06515 d9f0c9745d3dce298b5c5767b82c0096 483 Pfam PF00144 Beta-lactamase 34 353 4.4E-66 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS06515 d9f0c9745d3dce298b5c5767b82c0096 483 Gene3D G3DSA:3.40.710.10 31 367 2.0E-82 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS06515 d9f0c9745d3dce298b5c5767b82c0096 483 PANTHER PTHR22935 29 420 4.1E-74 T 23-04-2016 DC74_RS08055 1a069f2c8445484c48b70003e4bbc5fc 570 SMART SM00327 360 558 2.4E-7 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS08055 1a069f2c8445484c48b70003e4bbc5fc 570 Gene3D G3DSA:3.40.190.10 271 336 1.3E-4 T 23-04-2016 DC74_RS08055 1a069f2c8445484c48b70003e4bbc5fc 570 Gene3D G3DSA:3.40.190.10 7 148 1.3E-4 T 23-04-2016 DC74_RS08055 1a069f2c8445484c48b70003e4bbc5fc 570 SUPERFAMILY SSF53850 34 328 1.59E-14 T 23-04-2016 DC74_RS08055 1a069f2c8445484c48b70003e4bbc5fc 570 Gene3D G3DSA:3.40.50.410 361 561 1.8E-9 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS08055 1a069f2c8445484c48b70003e4bbc5fc 570 Pfam PF13531 Bacterial extracellular solute-binding protein 37 312 3.4E-35 T 23-04-2016 DC74_RS08055 1a069f2c8445484c48b70003e4bbc5fc 570 SUPERFAMILY SSF53300 362 558 4.08E-17 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Gene3D G3DSA:3.40.50.980 455 622 4.4E-49 T 23-04-2016 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Gene3D G3DSA:3.40.50.980 623 785 1.9E-30 T 23-04-2016 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 SMART SM00824 Thioesterase 1085 1311 7.6E-8 T 23-04-2016 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 ProSitePatterns PS00455 Putative AMP-binding domain signature. 614 625 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Gene3D G3DSA:2.30.38.10 786 863 2.0E-27 T 23-04-2016 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 SUPERFAMILY SSF56801 420 1000 6.15E-155 T 23-04-2016 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 PANTHER PTHR24095:SF137 1 345 0.0 T 23-04-2016 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 PANTHER PTHR24095:SF137 362 1084 0.0 T 23-04-2016 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Pfam PF13193 AMP-binding enzyme C-terminal domain 881 962 8.9E-14 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 SUPERFAMILY SSF53474 1058 1311 2.6E-54 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 483 897 2.6E-121 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Pfam PF00501 AMP-binding enzyme 462 873 3.9E-97 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1011 1026 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Pfam PF13745 HxxPF-repeated domain 312 407 1.3E-28 T 23-04-2016 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 SUPERFAMILY SSF47336 982 1052 8.64E-19 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Gene3D G3DSA:3.40.50.1820 1077 1186 5.2E-50 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Gene3D G3DSA:3.40.50.1820 1245 1313 5.2E-50 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Gene3D G3DSA:3.30.300.30 868 991 2.9E-40 T 23-04-2016 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 SUPERFAMILY SSF52777 180 448 5.78E-62 T 23-04-2016 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Pfam PF00975 Thioesterase domain 1083 1300 4.0E-31 T 23-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 SUPERFAMILY SSF52777 1 172 7.0E-47 T 23-04-2016 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 PANTHER PTHR24095 1 345 0.0 T 23-04-2016 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Pfam PF00550 Phosphopantetheine attachment site 989 1051 3.1E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 PANTHER PTHR24095 362 1084 0.0 T 23-04-2016 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Pfam PF00668 Condensation domain 1 290 8.9E-62 T 23-04-2016 IPR001242 Condensation domain DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 SMART SM00823 Phosphopantetheine attachment site 987 1056 6.1E-5 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS05705 2845fdbc92d9e13ebc611ebb5bfa5179 1316 Gene3D G3DSA:1.10.1200.10 992 1056 4.1E-23 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS19075 9e5700e022ac76843a64b363b34aa5d8 119 PANTHER PTHR11058 2 119 6.4E-53 T 23-04-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 DC74_RS19075 9e5700e022ac76843a64b363b34aa5d8 119 PANTHER PTHR11058:SF5 2 119 6.4E-53 T 23-04-2016 DC74_RS19075 9e5700e022ac76843a64b363b34aa5d8 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 19 118 2.4E-36 T 23-04-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 DC74_RS19075 9e5700e022ac76843a64b363b34aa5d8 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 119 17.71 T 23-04-2016 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 DC74_RS06165 deff15be081e50887d080741bdb9be81 228 SUPERFAMILY SSF46955 120 225 1.24E-16 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS06165 deff15be081e50887d080741bdb9be81 228 SUPERFAMILY SSF46955 7 109 3.39E-13 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS06165 deff15be081e50887d080741bdb9be81 228 Pfam PF00376 MerR family regulatory protein 7 41 6.2E-11 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS06165 deff15be081e50887d080741bdb9be81 228 SMART SM00422 3 74 0.0024 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS06165 deff15be081e50887d080741bdb9be81 228 SMART SM00422 120 187 2.7E-6 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS06165 deff15be081e50887d080741bdb9be81 228 Gene3D G3DSA:1.10.1660.10 7 108 1.4E-15 T 23-04-2016 DC74_RS06165 deff15be081e50887d080741bdb9be81 228 Gene3D G3DSA:1.10.1660.10 120 225 1.8E-19 T 23-04-2016 DC74_RS06165 deff15be081e50887d080741bdb9be81 228 Pfam PF13411 MerR HTH family regulatory protein 120 186 2.4E-13 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17975 3f33d93777939d15b1370219544fef85 724 SUPERFAMILY SSF55804 2 144 1.96E-31 T 23-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 DC74_RS17975 3f33d93777939d15b1370219544fef85 724 Pfam PF02378 Phosphotransferase system, EIIC 361 638 4.0E-16 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 DC74_RS17975 3f33d93777939d15b1370219544fef85 724 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 227 309 3.4E-27 T 23-04-2016 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 DC74_RS17975 3f33d93777939d15b1370219544fef85 724 Gene3D G3DSA:3.40.930.10 1 145 2.7E-40 T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- DC74_RS17975 3f33d93777939d15b1370219544fef85 724 Gene3D G3DSA:3.40.50.2300 225 323 3.0E-37 T 23-04-2016 DC74_RS17975 3f33d93777939d15b1370219544fef85 724 PANTHER PTHR30505:SF0 41 192 9.7E-240 T 23-04-2016 DC74_RS17975 3f33d93777939d15b1370219544fef85 724 PANTHER PTHR30505:SF0 225 714 9.7E-240 T 23-04-2016 DC74_RS17975 3f33d93777939d15b1370219544fef85 724 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 353 690 1.1E-111 T 23-04-2016 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 DC74_RS17975 3f33d93777939d15b1370219544fef85 724 SUPERFAMILY SSF52794 225 323 2.27E-30 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 DC74_RS17975 3f33d93777939d15b1370219544fef85 724 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 143 2.6E-30 T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- DC74_RS17975 3f33d93777939d15b1370219544fef85 724 PANTHER PTHR30505 41 192 9.7E-240 T 23-04-2016 DC74_RS17975 3f33d93777939d15b1370219544fef85 724 PANTHER PTHR30505 225 714 9.7E-240 T 23-04-2016 DC74_RS17975 3f33d93777939d15b1370219544fef85 724 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 228 317 1.8E-17 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 DC74_RS09950 93025ea5797c3ae6665edca564e81790 63 Pfam PF06348 Protein of unknown function (DUF1059) 3 56 6.8E-10 T 23-04-2016 IPR009409 Protein of unknown function DUF1059 DC74_RS35600 47347c0175d4c3b979fb3302d043aa5c 309 Pfam PF04389 Peptidase family M28 99 303 1.5E-47 T 23-04-2016 IPR007484 Peptidase M28 DC74_RS35600 47347c0175d4c3b979fb3302d043aa5c 309 SUPERFAMILY SSF53187 43 307 3.55E-68 T 23-04-2016 DC74_RS35600 47347c0175d4c3b979fb3302d043aa5c 309 Gene3D G3DSA:3.40.630.10 41 308 4.1E-76 T 23-04-2016 DC74_RS35600 47347c0175d4c3b979fb3302d043aa5c 309 PANTHER PTHR12147 20 256 4.9E-59 T 23-04-2016 DC74_RS35600 47347c0175d4c3b979fb3302d043aa5c 309 PANTHER PTHR12147 274 309 4.9E-59 T 23-04-2016 DC74_RS35600 47347c0175d4c3b979fb3302d043aa5c 309 PANTHER PTHR12147:SF23 20 256 4.9E-59 T 23-04-2016 DC74_RS35600 47347c0175d4c3b979fb3302d043aa5c 309 PANTHER PTHR12147:SF23 274 309 4.9E-59 T 23-04-2016 DC74_RS35155 7cf494404a2a8ba1941456d253505142 285 Pfam PF04072 Leucine carboxyl methyltransferase 13 190 8.8E-48 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS35155 7cf494404a2a8ba1941456d253505142 285 SUPERFAMILY SSF53335 10 281 1.21E-62 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS35155 7cf494404a2a8ba1941456d253505142 285 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 11 265 1.6E-46 T 23-04-2016 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS35155 7cf494404a2a8ba1941456d253505142 285 PANTHER PTHR13600:SF12 12 244 1.8E-39 T 23-04-2016 DC74_RS35155 7cf494404a2a8ba1941456d253505142 285 Gene3D G3DSA:3.40.50.150 62 200 1.9E-15 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS35155 7cf494404a2a8ba1941456d253505142 285 PANTHER PTHR13600 12 244 1.8E-39 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS23115 ddfceb93b7ef50f5a4682c4582404a45 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 141 2.3E-39 T 23-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 DC74_RS23115 ddfceb93b7ef50f5a4682c4582404a45 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 30.137 T 23-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 DC74_RS23115 ddfceb93b7ef50f5a4682c4582404a45 141 Gene3D G3DSA:3.50.80.10 1 140 4.1E-53 T 23-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain DC74_RS23115 ddfceb93b7ef50f5a4682c4582404a45 141 SUPERFAMILY SSF69500 1 140 1.7E-45 T 23-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain DC74_RS23115 ddfceb93b7ef50f5a4682c4582404a45 141 PANTHER PTHR10472 2 140 9.3E-58 T 23-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 DC74_RS23115 ddfceb93b7ef50f5a4682c4582404a45 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 6.5E-50 T 23-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 DC74_RS21380 08043aeca3af8460e8547a94355e55d7 163 SUPERFAMILY SSF46785 19 159 7.26E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21380 08043aeca3af8460e8547a94355e55d7 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 85 2.4E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21380 08043aeca3af8460e8547a94355e55d7 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 135 155 2.4E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21380 08043aeca3af8460e8547a94355e55d7 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 2.4E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21380 08043aeca3af8460e8547a94355e55d7 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 2.4E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21380 08043aeca3af8460e8547a94355e55d7 163 Pfam PF01047 MarR family 56 108 1.1E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21380 08043aeca3af8460e8547a94355e55d7 163 SMART SM00347 48 145 5.6E-14 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21380 08043aeca3af8460e8547a94355e55d7 163 Gene3D G3DSA:1.10.10.10 16 158 7.4E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21380 08043aeca3af8460e8547a94355e55d7 163 PANTHER PTHR33164:SF16 18 157 8.0E-19 T 23-04-2016 DC74_RS21380 08043aeca3af8460e8547a94355e55d7 163 PANTHER PTHR33164 18 157 8.0E-19 T 23-04-2016 DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 SUPERFAMILY SSF55874 851 928 1.35E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 Gene3D G3DSA:3.30.450.20 32 169 4.0E-34 T 23-04-2016 DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 PANTHER PTHR21021:SF19 672 815 2.1E-50 T 23-04-2016 DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 Gene3D G3DSA:3.30.450.40 330 504 5.4E-40 T 23-04-2016 IPR029016 GAF domain-like DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 SMART SM00331 524 806 4.1E-33 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 SUPERFAMILY SSF103190 39 166 2.24E-24 T 23-04-2016 IPR029151 Periplasmic sensor domain-like DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 PANTHER PTHR21021 419 602 2.1E-50 T 23-04-2016 DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 Pfam PF01590 GAF domain 380 496 1.1E-8 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 SUPERFAMILY SSF81606 676 805 3.92E-6 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 PANTHER PTHR21021:SF19 419 602 2.1E-50 T 23-04-2016 DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 551 806 1.4E-45 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 SUPERFAMILY SSF55781 397 500 1.64E-14 T 23-04-2016 IPR029016 GAF domain-like DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 Pfam PF13581 Histidine kinase-like ATPase domain 819 927 6.3E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 Pfam PF17203 Single cache domain 3 36 161 6.0E-20 T 23-04-2016 IPR033463 Single cache domain 3 DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 SMART SM00065 331 506 1.1E-9 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 Gene3D G3DSA:3.30.450.20 213 310 2.4E-5 T 23-04-2016 DC74_RS31060 d80aae0c4caeca85181e82c96d89455d 958 PANTHER PTHR21021 672 815 2.1E-50 T 23-04-2016 DC74_RS25910 f3a03d713bad9b4babd6fd452b15560b 298 Pfam PF13371 Tetratricopeptide repeat 216 287 2.8E-10 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS25910 f3a03d713bad9b4babd6fd452b15560b 298 PANTHER PTHR31350 82 282 6.7E-31 T 23-04-2016 DC74_RS25910 f3a03d713bad9b4babd6fd452b15560b 298 Pfam PF13369 Transglutaminase-like superfamily 83 214 2.1E-42 T 23-04-2016 IPR032698 Protein SirB1, N-terminal DC74_RS23630 67ef535b6c22e4b5443368e27a63aae5 698 PANTHER PTHR11070 405 688 4.3E-223 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS23630 67ef535b6c22e4b5443368e27a63aae5 698 PANTHER PTHR11070 99 367 4.3E-223 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS23630 67ef535b6c22e4b5443368e27a63aae5 698 Gene3D G3DSA:3.40.50.300 532 692 8.8E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23630 67ef535b6c22e4b5443368e27a63aae5 698 PANTHER PTHR11070:SF25 99 367 4.3E-223 T 23-04-2016 DC74_RS23630 67ef535b6c22e4b5443368e27a63aae5 698 SUPERFAMILY SSF52540 188 267 1.4E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23630 67ef535b6c22e4b5443368e27a63aae5 698 SUPERFAMILY SSF52540 456 689 1.4E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23630 67ef535b6c22e4b5443368e27a63aae5 698 Gene3D G3DSA:3.40.50.300 392 522 3.7E-30 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23630 67ef535b6c22e4b5443368e27a63aae5 698 Gene3D G3DSA:3.40.50.300 195 257 3.7E-30 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23630 67ef535b6c22e4b5443368e27a63aae5 698 PANTHER PTHR11070:SF25 405 688 4.3E-223 T 23-04-2016 DC74_RS23630 67ef535b6c22e4b5443368e27a63aae5 698 Pfam PF13245 Part of AAA domain 209 270 7.9E-13 T 23-04-2016 DC74_RS04410 ed0fb3c6081e442bfec5533453fbbd7f 235 Gene3D G3DSA:3.40.50.1860 1 112 1.4E-42 T 23-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS04410 ed0fb3c6081e442bfec5533453fbbd7f 235 PANTHER PTHR21198:SF7 1 227 1.5E-84 T 23-04-2016 DC74_RS04410 ed0fb3c6081e442bfec5533453fbbd7f 235 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 230 1.1E-72 T 23-04-2016 IPR004380 Aspartate racemase GO:0006520|GO:0016855 DC74_RS04410 ed0fb3c6081e442bfec5533453fbbd7f 235 SUPERFAMILY SSF53681 1 116 1.18E-35 T 23-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS04410 ed0fb3c6081e442bfec5533453fbbd7f 235 Gene3D G3DSA:3.40.50.1860 113 213 4.0E-35 T 23-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS04410 ed0fb3c6081e442bfec5533453fbbd7f 235 PANTHER PTHR21198 1 227 1.5E-84 T 23-04-2016 DC74_RS04410 ed0fb3c6081e442bfec5533453fbbd7f 235 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 223 8.4E-57 T 23-04-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS04410 ed0fb3c6081e442bfec5533453fbbd7f 235 SUPERFAMILY SSF53681 118 228 1.64E-33 T 23-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS30520 2762961c22a7254fc5ba511544747796 375 Pfam PF00877 NlpC/P60 family 264 363 6.0E-19 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS30520 2762961c22a7254fc5ba511544747796 375 Gene3D G3DSA:3.90.1720.10 246 364 1.5E-35 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS30520 2762961c22a7254fc5ba511544747796 375 SUPERFAMILY SSF54001 245 366 2.42E-31 T 23-04-2016 DC74_RS30520 2762961c22a7254fc5ba511544747796 375 PANTHER PTHR21666 255 363 5.6E-23 T 23-04-2016 DC74_RS08040 7eb2cdbaa4876575ce059a4c5d05bd30 140 PANTHER PTHR33169 1 110 3.3E-32 T 23-04-2016 DC74_RS08040 7eb2cdbaa4876575ce059a4c5d05bd30 140 SUPERFAMILY SSF46785 2 77 8.95E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08040 7eb2cdbaa4876575ce059a4c5d05bd30 140 Gene3D G3DSA:1.10.10.10 2 73 5.9E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08040 7eb2cdbaa4876575ce059a4c5d05bd30 140 Pfam PF03551 Transcriptional regulator PadR-like family 5 71 2.8E-21 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS08040 7eb2cdbaa4876575ce059a4c5d05bd30 140 PANTHER PTHR33169:SF11 1 110 3.3E-32 T 23-04-2016 DC74_RS35880 207f76c5993c68b53b00d39073257fa0 252 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 33 195 3.7E-20 T 23-04-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain DC74_RS35880 207f76c5993c68b53b00d39073257fa0 252 PANTHER PTHR30134 3 228 4.3E-90 T 23-04-2016 DC74_RS35880 207f76c5993c68b53b00d39073257fa0 252 SUPERFAMILY SSF52540 3 218 1.01E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35880 207f76c5993c68b53b00d39073257fa0 252 Gene3D G3DSA:3.40.50.300 33 140 9.0E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35880 207f76c5993c68b53b00d39073257fa0 252 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 4 210 5.3E-66 T 23-04-2016 IPR004392 Hydrogenase accessory protein HypB GO:0006461|GO:0016151 DC74_RS35880 207f76c5993c68b53b00d39073257fa0 252 PIRSF PIRSF005624 1 229 2.8E-82 T 23-04-2016 DC74_RS35880 207f76c5993c68b53b00d39073257fa0 252 PANTHER PTHR30134:SF2 3 228 4.3E-90 T 23-04-2016 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 PANTHER PTHR22600 29 528 3.6E-162 T 23-04-2016 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 Gene3D G3DSA:3.20.20.80 172 522 6.1E-108 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 174 493 8.3E-84 T 23-04-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 SUPERFAMILY SSF51445 174 522 3.61E-111 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 Gene3D G3DSA:3.30.379.10 4 171 4.6E-37 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 38 171 4.3E-25 T 23-04-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 PRINTS PR00738 Glycosyl hydrolase family 20 signature 256 273 1.6E-49 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 PRINTS PR00738 Glycosyl hydrolase family 20 signature 126 146 1.6E-49 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 PRINTS PR00738 Glycosyl hydrolase family 20 signature 197 218 1.6E-49 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 PRINTS PR00738 Glycosyl hydrolase family 20 signature 326 339 1.6E-49 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 PRINTS PR00738 Glycosyl hydrolase family 20 signature 457 473 1.6E-49 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 PRINTS PR00738 Glycosyl hydrolase family 20 signature 168 185 1.6E-49 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 PRINTS PR00738 Glycosyl hydrolase family 20 signature 304 322 1.6E-49 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 PRINTS PR00738 Glycosyl hydrolase family 20 signature 475 492 1.6E-49 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 SUPERFAMILY SSF55545 31 173 6.02E-33 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like DC74_RS15925 565534752e51ef8abc67f2d9c96b1774 531 PANTHER PTHR22600:SF21 29 528 3.6E-162 T 23-04-2016 DC74_RS24655 acf5ec1e2c9d82feb29fef3c94900073 405 SUPERFAMILY SSF51735 44 151 2.97E-5 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS24655 acf5ec1e2c9d82feb29fef3c94900073 405 PANTHER PTHR37480 6 405 9.3E-120 T 23-04-2016 DC74_RS24655 acf5ec1e2c9d82feb29fef3c94900073 405 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 8 84 4.3E-20 T 23-04-2016 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 DC74_RS24655 acf5ec1e2c9d82feb29fef3c94900073 405 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 87 319 2.6E-79 T 23-04-2016 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 DC74_RS24655 acf5ec1e2c9d82feb29fef3c94900073 405 Pfam PF07055 Enoyl reductase FAD binding domain 331 394 1.6E-23 T 23-04-2016 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 DC74_RS24655 acf5ec1e2c9d82feb29fef3c94900073 405 Gene3D G3DSA:3.40.50.720 43 147 6.6E-7 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS24655 acf5ec1e2c9d82feb29fef3c94900073 405 Gene3D G3DSA:3.40.50.720 189 204 6.6E-7 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18485 6b3544c2a2b3962cac5a1bb35fd9bfb9 102 PANTHER PTHR10772 10 101 4.2E-39 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS18485 6b3544c2a2b3962cac5a1bb35fd9bfb9 102 Pfam PF00166 Chaperonin 10 Kd subunit 10 100 1.4E-32 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS18485 6b3544c2a2b3962cac5a1bb35fd9bfb9 102 ProSitePatterns PS00681 Chaperonins cpn10 signature. 10 34 - T 23-04-2016 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 DC74_RS18485 6b3544c2a2b3962cac5a1bb35fd9bfb9 102 SMART SM00883 9 100 1.0E-49 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS18485 6b3544c2a2b3962cac5a1bb35fd9bfb9 102 Hamap MF_00580 10 kDa chaperonin [groS]. 9 101 25.329 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS18485 6b3544c2a2b3962cac5a1bb35fd9bfb9 102 Gene3D G3DSA:2.30.33.40 10 101 4.6E-36 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS18485 6b3544c2a2b3962cac5a1bb35fd9bfb9 102 PRINTS PR00297 10kDa chaperonin signature 10 25 6.1E-31 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS18485 6b3544c2a2b3962cac5a1bb35fd9bfb9 102 PRINTS PR00297 10kDa chaperonin signature 32 53 6.1E-31 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS18485 6b3544c2a2b3962cac5a1bb35fd9bfb9 102 PRINTS PR00297 10kDa chaperonin signature 87 100 6.1E-31 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS18485 6b3544c2a2b3962cac5a1bb35fd9bfb9 102 PRINTS PR00297 10kDa chaperonin signature 66 78 6.1E-31 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS18485 6b3544c2a2b3962cac5a1bb35fd9bfb9 102 SUPERFAMILY SSF50129 9 101 3.38E-32 T 23-04-2016 IPR011032 GroES-like DC74_RS37055 dadfac817bfd3ddbb68ebd03fdd661eb 86 Pfam PF00550 Phosphopantetheine attachment site 15 72 5.0E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS37055 dadfac817bfd3ddbb68ebd03fdd661eb 86 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 33 75 6.0E-5 T 23-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 DC74_RS37055 dadfac817bfd3ddbb68ebd03fdd661eb 86 Gene3D G3DSA:1.10.1200.10 3 76 1.3E-16 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS37055 dadfac817bfd3ddbb68ebd03fdd661eb 86 SUPERFAMILY SSF47336 15 84 5.76E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS32200 c128add89fbc11388b1af3a80ace490a 243 Gene3D G3DSA:1.10.260.40 1 58 7.5E-4 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS06475 5de617cc9500fa4d17aaeea87bba95e4 466 Pfam PF09471 IgA Peptidase M64 78 334 8.7E-65 T 23-04-2016 IPR019026 Peptidase M64, IgA DC74_RS06475 5de617cc9500fa4d17aaeea87bba95e4 466 Gene3D G3DSA:3.40.390.10 185 247 5.9E-4 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 DC74_RS26515 dff63bdbefeedf127b71325429201110 301 PIRSF PIRSF006278 4 301 3.0E-76 T 23-04-2016 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase DC74_RS26515 dff63bdbefeedf127b71325429201110 301 SUPERFAMILY SSF53686 13 299 1.15E-49 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS26515 dff63bdbefeedf127b71325429201110 301 PANTHER PTHR10314:SF105 30 194 2.6E-31 T 23-04-2016 DC74_RS26515 dff63bdbefeedf127b71325429201110 301 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 14 299 6.7E-19 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS26515 dff63bdbefeedf127b71325429201110 301 Gene3D G3DSA:3.40.50.1100 110 299 5.5E-41 T 23-04-2016 DC74_RS26515 dff63bdbefeedf127b71325429201110 301 Gene3D G3DSA:3.40.50.1100 66 109 9.3E-5 T 23-04-2016 DC74_RS26515 dff63bdbefeedf127b71325429201110 301 PANTHER PTHR10314 30 194 2.6E-31 T 23-04-2016 DC74_RS11645 77f7d647cec6e3d43ee996a5b32c4f74 326 SUPERFAMILY SSF51569 18 312 2.41E-60 T 23-04-2016 DC74_RS11645 77f7d647cec6e3d43ee996a5b32c4f74 326 Gene3D G3DSA:3.20.20.70 18 313 9.0E-73 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS11645 77f7d647cec6e3d43ee996a5b32c4f74 326 PANTHER PTHR12128:SF19 22 312 5.4E-122 T 23-04-2016 DC74_RS11645 77f7d647cec6e3d43ee996a5b32c4f74 326 PANTHER PTHR12128 22 312 5.4E-122 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS11645 77f7d647cec6e3d43ee996a5b32c4f74 326 PIRSF PIRSF001365 17 321 6.2E-54 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS11645 77f7d647cec6e3d43ee996a5b32c4f74 326 Pfam PF00701 Dihydrodipicolinate synthetase family 21 311 3.4E-49 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS11645 77f7d647cec6e3d43ee996a5b32c4f74 326 SMART SM01130 19 314 1.4E-66 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS20100 527a9b7619e8588ed4cd1638988ae42e 151 SUPERFAMILY SSF158682 21 150 4.45E-24 T 23-04-2016 IPR029024 TerB-like DC74_RS20100 527a9b7619e8588ed4cd1638988ae42e 151 Gene3D G3DSA:1.10.3680.10 21 150 1.6E-25 T 23-04-2016 IPR029024 TerB-like DC74_RS20100 527a9b7619e8588ed4cd1638988ae42e 151 Pfam PF05099 Tellurite resistance protein TerB 11 150 1.7E-31 T 23-04-2016 IPR007791 Co-chaperone DjlA, N-terminal DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 SUPERFAMILY SSF55826 247 401 1.14E-21 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 101 461 3.1E-42 T 23-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 9 562 3.7E-176 T 23-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 Hamap MF_01569 Proline--tRNA ligase [proS]. 8 567 36.504 T 23-04-2016 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 Pfam PF04073 Aminoacyl-tRNA editing domain 263 381 1.0E-25 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 SUPERFAMILY SSF55681 409 480 4.38E-87 T 23-04-2016 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 SUPERFAMILY SSF55681 17 244 4.38E-87 T 23-04-2016 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 Pfam PF03129 Anticodon binding domain 478 565 6.9E-16 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 SUPERFAMILY SSF52954 463 565 3.27E-24 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 PANTHER PTHR11451:SF3 11 251 2.4E-132 T 23-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 PANTHER PTHR11451:SF3 400 565 2.4E-132 T 23-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 111 122 4.3E-16 T 23-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 141 149 4.3E-16 T 23-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 75 93 4.3E-16 T 23-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 151 162 4.3E-16 T 23-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 Gene3D G3DSA:3.30.930.10 18 241 1.1E-94 T 23-04-2016 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 Gene3D G3DSA:3.30.930.10 391 473 1.1E-94 T 23-04-2016 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 Gene3D G3DSA:3.90.960.10 245 389 3.9E-20 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 Gene3D G3DSA:3.40.50.800 474 565 3.9E-23 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 PANTHER PTHR11451 11 251 2.4E-132 T 23-04-2016 DC74_RS28405 3f1d932efe9860b239dc7752212ca158 567 PANTHER PTHR11451 400 565 2.4E-132 T 23-04-2016 DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 263 4.5E-49 T 23-04-2016 DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PANTHER PTHR24322:SF390 170 201 6.1E-51 T 23-04-2016 DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PANTHER PTHR24322:SF390 15 154 6.1E-51 T 23-04-2016 DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 SUPERFAMILY SSF51735 9 263 5.27E-66 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PANTHER PTHR24322 170 201 6.1E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PANTHER PTHR24322 15 154 6.1E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 1.6E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 1.6E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 1.6E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.6E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 1.6E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 1.6E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 6.4E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 6.4E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 6.4E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 Gene3D G3DSA:3.40.50.720 7 263 1.5E-74 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS14710 431d84a83211e109a4bf735fe1e871f1 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS25170 7b494847e6f9e7b986e54ec41406765d 430 Pfam PF13205 Bacterial Ig-like domain 168 261 4.9E-7 T 23-04-2016 IPR032812 SbsA, Ig-like domain DC74_RS25170 7b494847e6f9e7b986e54ec41406765d 430 SUPERFAMILY SSF141523 269 400 4.71E-25 T 23-04-2016 DC74_RS25170 7b494847e6f9e7b986e54ec41406765d 430 Pfam PF03734 L,D-transpeptidase catalytic domain 267 400 1.3E-14 T 23-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 DC74_RS25170 7b494847e6f9e7b986e54ec41406765d 430 PANTHER PTHR30582 56 430 1.4E-108 T 23-04-2016 DC74_RS25170 7b494847e6f9e7b986e54ec41406765d 430 PANTHER PTHR30582:SF2 56 430 1.4E-108 T 23-04-2016 DC74_RS25170 7b494847e6f9e7b986e54ec41406765d 430 Gene3D G3DSA:2.40.440.10 269 402 3.3E-21 T 23-04-2016 DC74_RS35910 0619d182508818b4357dfc905a1f953b 389 Gene3D G3DSA:3.40.50.1820 298 363 8.2E-26 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35910 0619d182508818b4357dfc905a1f953b 389 Gene3D G3DSA:3.40.50.1820 74 250 8.2E-26 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35910 0619d182508818b4357dfc905a1f953b 389 PIRSF PIRSF029171 1 388 5.4E-75 T 23-04-2016 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 DC74_RS35910 0619d182508818b4357dfc905a1f953b 389 SUPERFAMILY SSF53474 294 377 3.35E-24 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35910 0619d182508818b4357dfc905a1f953b 389 SUPERFAMILY SSF53474 74 224 3.35E-24 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35910 0619d182508818b4357dfc905a1f953b 389 Pfam PF03583 Secretory lipase 117 386 6.7E-56 T 23-04-2016 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 DC74_RS35910 0619d182508818b4357dfc905a1f953b 389 PANTHER PTHR34853 28 388 7.1E-74 T 23-04-2016 DC74_RS27135 55c5a48eea73ba846f36eb9fa42580e9 340 Gene3D G3DSA:3.40.50.300 1 224 5.4E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27135 55c5a48eea73ba846f36eb9fa42580e9 340 PANTHER PTHR24220 3 224 5.7E-119 T 23-04-2016 DC74_RS27135 55c5a48eea73ba846f36eb9fa42580e9 340 PANTHER PTHR24220:SF523 3 224 5.7E-119 T 23-04-2016 DC74_RS27135 55c5a48eea73ba846f36eb9fa42580e9 340 SMART SM00382 26 204 3.2E-7 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS27135 55c5a48eea73ba846f36eb9fa42580e9 340 Pfam PF00005 ABC transporter 18 156 3.1E-21 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS27135 55c5a48eea73ba846f36eb9fa42580e9 340 SUPERFAMILY SSF52540 2 225 2.07E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25645 ca2d24dc5bcb8eecf53f861e3d392b3c 330 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 11 294 36.563 T 23-04-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 DC74_RS25645 ca2d24dc5bcb8eecf53f861e3d392b3c 330 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 12 290 1.4E-95 T 23-04-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 DC74_RS25645 ca2d24dc5bcb8eecf53f861e3d392b3c 330 PANTHER PTHR30426 11 321 8.3E-149 T 23-04-2016 DC74_RS25645 ca2d24dc5bcb8eecf53f861e3d392b3c 330 Pfam PF02401 LytB protein 13 290 8.4E-88 T 23-04-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 DC74_RS31285 73a7708ef8075a74b159bbebc6b3a6bc 566 Gene3D G3DSA:3.40.50.980 207 352 2.7E-53 T 23-04-2016 DC74_RS31285 73a7708ef8075a74b159bbebc6b3a6bc 566 PANTHER PTHR24095 17 546 6.7E-206 T 23-04-2016 DC74_RS31285 73a7708ef8075a74b159bbebc6b3a6bc 566 Gene3D G3DSA:2.30.38.10 360 434 7.4E-29 T 23-04-2016 DC74_RS31285 73a7708ef8075a74b159bbebc6b3a6bc 566 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS31285 73a7708ef8075a74b159bbebc6b3a6bc 566 Pfam PF00501 AMP-binding enzyme 31 443 2.2E-114 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS31285 73a7708ef8075a74b159bbebc6b3a6bc 566 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 528 2.9E-19 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS31285 73a7708ef8075a74b159bbebc6b3a6bc 566 SUPERFAMILY SSF56801 23 540 8.37E-164 T 23-04-2016 DC74_RS31285 73a7708ef8075a74b159bbebc6b3a6bc 566 Gene3D G3DSA:3.40.50.980 24 206 2.2E-41 T 23-04-2016 DC74_RS31285 73a7708ef8075a74b159bbebc6b3a6bc 566 Gene3D G3DSA:3.30.300.30 438 538 2.8E-33 T 23-04-2016 DC74_RS01130 2f3eb5dc1e2451f1a5666bc980fd6e74 297 PANTHER PTHR11695 15 297 4.8E-64 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS01130 2f3eb5dc1e2451f1a5666bc980fd6e74 297 SUPERFAMILY SSF50129 1 147 6.7E-28 T 23-04-2016 IPR011032 GroES-like DC74_RS01130 2f3eb5dc1e2451f1a5666bc980fd6e74 297 Pfam PF13602 Zinc-binding dehydrogenase 189 294 1.1E-13 T 23-04-2016 DC74_RS01130 2f3eb5dc1e2451f1a5666bc980fd6e74 297 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 89 6.4E-9 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS01130 2f3eb5dc1e2451f1a5666bc980fd6e74 297 PANTHER PTHR11695:SF605 15 297 4.8E-64 T 23-04-2016 DC74_RS01130 2f3eb5dc1e2451f1a5666bc980fd6e74 297 Gene3D G3DSA:3.40.50.720 144 237 2.2E-13 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01130 2f3eb5dc1e2451f1a5666bc980fd6e74 297 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 138 159 - T 23-04-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 DC74_RS01130 2f3eb5dc1e2451f1a5666bc980fd6e74 297 SUPERFAMILY SSF51735 111 292 1.35E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01130 2f3eb5dc1e2451f1a5666bc980fd6e74 297 Gene3D G3DSA:3.90.180.10 1 143 3.3E-35 T 23-04-2016 IPR011032 GroES-like DC74_RS01130 2f3eb5dc1e2451f1a5666bc980fd6e74 297 SMART SM00829 10 295 7.5E-13 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 SUPERFAMILY SSF51735 8 254 1.77E-66 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 252 7.7E-55 T 23-04-2016 DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 Gene3D G3DSA:3.40.50.720 4 253 1.3E-72 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 8.4E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 8.4E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 8.4E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 8.4E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 8.4E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 8.4E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 PANTHER PTHR24321 5 253 2.4E-39 T 23-04-2016 DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 PANTHER PTHR24321:SF6 5 253 2.4E-39 T 23-04-2016 DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 6.5E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 6.5E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS05105 a67c08a7452d91d2a67ffacb89b76ca9 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 6.5E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22985 d9cf39012b3e8c1a429c8fc21f618221 151 PANTHER PTHR10245:SF36 8 126 7.0E-57 T 23-04-2016 DC74_RS22985 d9cf39012b3e8c1a429c8fc21f618221 151 SUPERFAMILY SSF47413 8 69 1.32E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS22985 d9cf39012b3e8c1a429c8fc21f618221 151 SMART SM00530 12 67 1.2E-15 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS22985 d9cf39012b3e8c1a429c8fc21f618221 151 Gene3D G3DSA:1.10.260.40 8 109 5.3E-21 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS22985 d9cf39012b3e8c1a429c8fc21f618221 151 Pfam PF01381 Helix-turn-helix 13 65 1.5E-14 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS22985 d9cf39012b3e8c1a429c8fc21f618221 151 PANTHER PTHR10245 8 126 7.0E-57 T 23-04-2016 DC74_RS33650 157e5eef3c678224ccae2b4639b63074 479 Pfam PF13520 Amino acid permease 35 450 9.5E-58 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS33650 157e5eef3c678224ccae2b4639b63074 479 PIRSF PIRSF006060 14 475 2.1E-88 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS33650 157e5eef3c678224ccae2b4639b63074 479 PANTHER PTHR11785 1 466 7.3E-137 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 Gene3D G3DSA:3.40.630.10 220 430 3.8E-102 T 23-04-2016 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 Gene3D G3DSA:3.40.630.10 11 90 3.8E-102 T 23-04-2016 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 Gene3D G3DSA:2.30.250.10 91 217 3.9E-39 T 23-04-2016 IPR023358 Peptidase M18, domain 2 GO:0004177 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 PANTHER PTHR28570 13 431 4.2E-166 T 23-04-2016 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 18 428 1.9E-124 T 23-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 Hamap MF_00467 Probable M18 family aminopeptidase 2 [apeB]. 1 431 56.398 T 23-04-2016 IPR022984 M18 family aminopeptidase 2, putative GO:0004177 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 113 133 1.1E-36 T 23-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 396 411 1.1E-36 T 23-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 307 323 1.1E-36 T 23-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 264 282 1.1E-36 T 23-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 80 96 1.1E-36 T 23-04-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 SUPERFAMILY SSF53187 211 430 4.94E-95 T 23-04-2016 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 SUPERFAMILY SSF53187 9 91 4.94E-95 T 23-04-2016 DC74_RS20280 bef5480f0263951557a35988fb835df3 431 SUPERFAMILY SSF101821 92 211 4.67E-31 T 23-04-2016 DC74_RS12025 be9a18fa4fd66d12946eb0b1927c9d9f 112 Pfam PF05899 Protein of unknown function (DUF861) 37 108 1.8E-17 T 23-04-2016 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 DC74_RS12025 be9a18fa4fd66d12946eb0b1927c9d9f 112 Gene3D G3DSA:2.60.120.10 14 110 7.4E-26 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS12025 be9a18fa4fd66d12946eb0b1927c9d9f 112 PANTHER PTHR40943 8 110 1.1E-30 T 23-04-2016 DC74_RS12025 be9a18fa4fd66d12946eb0b1927c9d9f 112 SUPERFAMILY SSF51182 3 109 4.32E-15 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS22360 b57a001603e4bbddc4f67c7c7dce664e 287 Pfam PF13560 Helix-turn-helix domain 16 78 2.6E-13 T 23-04-2016 DC74_RS22360 b57a001603e4bbddc4f67c7c7dce664e 287 Gene3D G3DSA:1.10.260.40 15 70 2.4E-6 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS22360 b57a001603e4bbddc4f67c7c7dce664e 287 PANTHER PTHR10245:SF20 11 287 6.2E-107 T 23-04-2016 DC74_RS22360 b57a001603e4bbddc4f67c7c7dce664e 287 SUPERFAMILY SSF47413 13 71 5.07E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS22360 b57a001603e4bbddc4f67c7c7dce664e 287 PANTHER PTHR10245 11 287 6.2E-107 T 23-04-2016 DC74_RS22360 b57a001603e4bbddc4f67c7c7dce664e 287 SMART SM00530 19 74 4.8E-5 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS17240 a86631f050962c327f244967c8a4d0bf 338 PANTHER PTHR24220:SF414 33 271 2.0E-90 T 23-04-2016 DC74_RS17240 a86631f050962c327f244967c8a4d0bf 338 Gene3D G3DSA:3.40.50.300 28 253 4.9E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17240 a86631f050962c327f244967c8a4d0bf 338 SUPERFAMILY SSF52540 20 249 3.55E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17240 a86631f050962c327f244967c8a4d0bf 338 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS17240 a86631f050962c327f244967c8a4d0bf 338 SMART SM00382 56 235 2.6E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS17240 a86631f050962c327f244967c8a4d0bf 338 Pfam PF00005 ABC transporter 47 185 3.5E-25 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS17240 a86631f050962c327f244967c8a4d0bf 338 PANTHER PTHR24220 33 271 2.0E-90 T 23-04-2016 DC74_RS22375 a328298384a3f88c3b2f41c37f04e89f 215 PANTHER PTHR33169 1 190 1.3E-73 T 23-04-2016 DC74_RS22375 a328298384a3f88c3b2f41c37f04e89f 215 Pfam PF03551 Transcriptional regulator PadR-like family 8 84 4.5E-11 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS22375 a328298384a3f88c3b2f41c37f04e89f 215 Gene3D G3DSA:1.10.10.10 4 89 4.9E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22375 a328298384a3f88c3b2f41c37f04e89f 215 PANTHER PTHR33169:SF5 1 190 1.3E-73 T 23-04-2016 DC74_RS22375 a328298384a3f88c3b2f41c37f04e89f 215 SUPERFAMILY SSF46785 4 177 6.47E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 SUPERFAMILY SSF46565 3 99 3.27E-32 T 23-04-2016 IPR001623 DnaJ domain DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 Gene3D G3DSA:1.10.287.110 3 100 3.5E-32 T 23-04-2016 IPR001623 DnaJ domain DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 Pfam PF00226 DnaJ domain 4 65 1.1E-25 T 23-04-2016 IPR001623 DnaJ domain DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 PANTHER PTHR24078 3 357 8.1E-161 T 23-04-2016 DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 374 37.689 T 23-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 SUPERFAMILY SSF57938 130 210 3.53E-18 T 23-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 349 4.0E-119 T 23-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 Gene3D G3DSA:2.60.260.20 256 334 6.0E-21 T 23-04-2016 DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 Pfam PF01556 DnaJ C terminal domain 118 333 3.5E-39 T 23-04-2016 IPR002939 Chaperone DnaJ, C-terminal DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 SUPERFAMILY SSF49493 258 344 2.88E-21 T 23-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 Gene3D G3DSA:2.60.260.20 104 136 2.5E-21 T 23-04-2016 DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 Gene3D G3DSA:2.60.260.20 210 253 2.5E-21 T 23-04-2016 DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 SMART SM00271 3 60 8.2E-30 T 23-04-2016 IPR001623 DnaJ domain DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 PANTHER PTHR24078:SF190 3 357 8.1E-161 T 23-04-2016 DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 Pfam PF00684 DnaJ central domain 143 207 1.6E-12 T 23-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 PRINTS PR00625 DnaJ domain signature 24 39 2.1E-24 T 23-04-2016 IPR001623 DnaJ domain DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 PRINTS PR00625 DnaJ domain signature 40 60 2.1E-24 T 23-04-2016 IPR001623 DnaJ domain DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 PRINTS PR00625 DnaJ domain signature 60 79 2.1E-24 T 23-04-2016 IPR001623 DnaJ domain DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 PRINTS PR00625 DnaJ domain signature 6 24 2.1E-24 T 23-04-2016 IPR001623 DnaJ domain DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 23-04-2016 IPR018253 DnaJ domain, conserved site DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 Gene3D G3DSA:2.10.230.10 137 209 1.3E-19 T 23-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 SUPERFAMILY SSF49493 213 257 3.66E-19 T 23-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 DC74_RS15030 f4108f6a5e2ebaec7e0c992bac4db4cf 378 SUPERFAMILY SSF49493 115 148 3.66E-19 T 23-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 DC74_RS20150 efe578e1f2aeae993457be5ae6e15c75 502 SUPERFAMILY SSF55124 22 102 2.62E-17 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS20150 efe578e1f2aeae993457be5ae6e15c75 502 Gene3D G3DSA:3.30.413.10 368 440 8.2E-6 T 23-04-2016 DC74_RS20150 efe578e1f2aeae993457be5ae6e15c75 502 SUPERFAMILY SSF56014 367 440 7.59E-8 T 23-04-2016 DC74_RS20150 efe578e1f2aeae993457be5ae6e15c75 502 PANTHER PTHR32439 25 435 2.0E-50 T 23-04-2016 DC74_RS20150 efe578e1f2aeae993457be5ae6e15c75 502 PANTHER PTHR32439:SF3 25 435 2.0E-50 T 23-04-2016 DC74_RS20150 efe578e1f2aeae993457be5ae6e15c75 502 SUPERFAMILY SSF55124 216 361 3.6E-18 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS20150 efe578e1f2aeae993457be5ae6e15c75 502 Gene3D G3DSA:3.90.480.10 36 105 8.2E-23 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS20150 efe578e1f2aeae993457be5ae6e15c75 502 Gene3D G3DSA:3.90.480.10 284 362 8.2E-23 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS20150 efe578e1f2aeae993457be5ae6e15c75 502 TIGRFAM TIGR02435 CobG: precorrin-3B synthase 24 439 5.8E-74 T 23-04-2016 IPR012798 Cobalamin (vitamin B12) biosynthesis CobG-like DC74_RS20150 efe578e1f2aeae993457be5ae6e15c75 502 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 41 87 2.4E-12 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS20150 efe578e1f2aeae993457be5ae6e15c75 502 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 295 345 6.2E-9 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS11565 c060f5014dd9bb93ed444f2957707878 133 PANTHER PTHR33154:SF12 26 124 1.8E-31 T 23-04-2016 DC74_RS11565 c060f5014dd9bb93ed444f2957707878 133 SMART SM00418 35 112 1.2E-13 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS11565 c060f5014dd9bb93ed444f2957707878 133 SUPERFAMILY SSF46785 26 111 5.86E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11565 c060f5014dd9bb93ed444f2957707878 133 Gene3D G3DSA:1.10.10.10 20 111 5.0E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11565 c060f5014dd9bb93ed444f2957707878 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 2.4E-6 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS11565 c060f5014dd9bb93ed444f2957707878 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 83 98 2.4E-6 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS11565 c060f5014dd9bb93ed444f2957707878 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 2.4E-6 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS11565 c060f5014dd9bb93ed444f2957707878 133 PANTHER PTHR33154 26 124 1.8E-31 T 23-04-2016 DC74_RS28400 b728a9c76b0946aa20f6f405ffe8aed9 178 Gene3D G3DSA:3.40.630.30 36 173 3.3E-15 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS28400 b728a9c76b0946aa20f6f405ffe8aed9 178 SUPERFAMILY SSF55729 14 170 7.2E-15 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS28400 b728a9c76b0946aa20f6f405ffe8aed9 178 Pfam PF13508 Acetyltransferase (GNAT) domain 67 151 5.1E-9 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS00825 afa0b29ee16b78d6da100adaf44aa3bc 242 SUPERFAMILY SSF48498 82 168 8.9E-5 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS00825 afa0b29ee16b78d6da100adaf44aa3bc 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.6E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00825 afa0b29ee16b78d6da100adaf44aa3bc 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.6E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00825 afa0b29ee16b78d6da100adaf44aa3bc 242 Gene3D G3DSA:1.10.357.10 3 187 1.9E-34 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS00825 afa0b29ee16b78d6da100adaf44aa3bc 242 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 7.9E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00825 afa0b29ee16b78d6da100adaf44aa3bc 242 SUPERFAMILY SSF46689 5 76 1.84E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00825 afa0b29ee16b78d6da100adaf44aa3bc 242 PANTHER PTHR30055 10 230 3.5E-23 T 23-04-2016 DC74_RS33575 9285f4afd5e3042c9ebfca3a539ecf6a 153 SUPERFAMILY SSF89623 4 146 5.62E-47 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 DC74_RS33575 9285f4afd5e3042c9ebfca3a539ecf6a 153 Gene3D G3DSA:3.40.1400.10 6 149 4.8E-53 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 DC74_RS33575 9285f4afd5e3042c9ebfca3a539ecf6a 153 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 7 147 1.5E-40 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 DC74_RS33575 9285f4afd5e3042c9ebfca3a539ecf6a 153 PANTHER PTHR30345 7 151 8.2E-58 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 DC74_RS33575 9285f4afd5e3042c9ebfca3a539ecf6a 153 PIRSF PIRSF005384 5 149 1.4E-46 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 DC74_RS33575 9285f4afd5e3042c9ebfca3a539ecf6a 153 Pfam PF02502 Ribose/Galactose Isomerase 7 142 1.9E-45 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 DC74_RS04610 587e4c8c0211547974b51754a7d7a48e 848 Pfam PF12704 MacB-like periplasmic core domain 493 682 1.5E-11 T 23-04-2016 IPR025857 MacB-like periplasmic core domain DC74_RS04610 587e4c8c0211547974b51754a7d7a48e 848 Pfam PF12704 MacB-like periplasmic core domain 17 235 8.7E-16 T 23-04-2016 IPR025857 MacB-like periplasmic core domain DC74_RS04610 587e4c8c0211547974b51754a7d7a48e 848 PANTHER PTHR30489:SF9 1 193 7.5E-190 T 23-04-2016 DC74_RS04610 587e4c8c0211547974b51754a7d7a48e 848 PANTHER PTHR30489:SF9 243 848 7.5E-190 T 23-04-2016 DC74_RS04610 587e4c8c0211547974b51754a7d7a48e 848 Pfam PF02687 FtsX-like permease family 722 840 1.5E-20 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS04610 587e4c8c0211547974b51754a7d7a48e 848 Pfam PF02687 FtsX-like permease family 272 392 4.0E-24 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS04610 587e4c8c0211547974b51754a7d7a48e 848 PANTHER PTHR30489 1 193 7.5E-190 T 23-04-2016 DC74_RS04610 587e4c8c0211547974b51754a7d7a48e 848 PANTHER PTHR30489 243 848 7.5E-190 T 23-04-2016 DC74_RS25085 dbb93846b34c6df498e0d9bd3fb1c446 394 PANTHER PTHR10907:SF33 123 297 2.1E-25 T 23-04-2016 DC74_RS25085 dbb93846b34c6df498e0d9bd3fb1c446 394 PANTHER PTHR10907 123 297 2.1E-25 T 23-04-2016 DC74_RS25085 dbb93846b34c6df498e0d9bd3fb1c446 394 SUPERFAMILY SSF53474 126 382 8.31E-28 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS25085 dbb93846b34c6df498e0d9bd3fb1c446 394 Pfam PF00756 Putative esterase 146 384 4.0E-16 T 23-04-2016 IPR000801 Putative esterase DC74_RS25085 dbb93846b34c6df498e0d9bd3fb1c446 394 Gene3D G3DSA:3.40.50.1820 124 384 8.5E-37 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS25335 ff0efe6b2ee41ac328678da64ad9351a 605 PANTHER PTHR11561 14 604 0.0 T 23-04-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 DC74_RS25335 ff0efe6b2ee41ac328678da64ad9351a 605 PIRSF PIRSF001348 3 605 8.7E-280 T 23-04-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 DC74_RS25335 ff0efe6b2ee41ac328678da64ad9351a 605 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 7 605 52.37 T 23-04-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 DC74_RS25335 ff0efe6b2ee41ac328678da64ad9351a 605 Pfam PF00821 Phosphoenolpyruvate carboxykinase 18 604 2.7E-284 T 23-04-2016 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 DC74_RS25335 ff0efe6b2ee41ac328678da64ad9351a 605 Gene3D G3DSA:3.90.228.20 331 604 4.5E-103 T 23-04-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 DC74_RS25335 ff0efe6b2ee41ac328678da64ad9351a 605 Gene3D G3DSA:3.90.228.20 245 314 4.3E-33 T 23-04-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 DC74_RS25335 ff0efe6b2ee41ac328678da64ad9351a 605 Gene3D G3DSA:3.40.449.10 9 244 8.6E-98 T 23-04-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 DC74_RS25335 ff0efe6b2ee41ac328678da64ad9351a 605 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 269 277 - T 23-04-2016 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00138 DC74_RS25335 ff0efe6b2ee41ac328678da64ad9351a 605 SUPERFAMILY SSF68923 9 244 2.46E-96 T 23-04-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 DC74_RS25335 ff0efe6b2ee41ac328678da64ad9351a 605 SUPERFAMILY SSF53795 245 604 1.35E-159 T 23-04-2016 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 89 102 - T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 81 95 2.5E-20 T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 147 169 2.5E-20 T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 304 315 2.5E-20 T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 191 211 2.5E-20 T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 SUPERFAMILY SSF53223 26 159 1.98E-43 T 23-04-2016 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 PIRSF PIRSF000188 16 367 1.4E-139 T 23-04-2016 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 37 144 3.3E-25 T 23-04-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 SMART SM00839 159 366 2.5E-40 T 23-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 Gene3D G3DSA:3.40.192.10 22 162 4.4E-63 T 23-04-2016 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 225 312 4.6E-7 T 23-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 Gene3D G3DSA:3.40.50.720 163 354 1.6E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 SUPERFAMILY SSF51735 156 366 2.54E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 PANTHER PTHR11606 40 366 6.3E-139 T 23-04-2016 DC74_RS19675 086c68097ebc2da229967ec03c726d0d 367 PANTHER PTHR11606:SF3 40 366 6.3E-139 T 23-04-2016 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 DC74_RS20320 3cb0f5589ee73c8bb7951682f430b9c5 274 SUPERFAMILY SSF109854 3 159 5.95E-29 T 23-04-2016 DC74_RS20320 3cb0f5589ee73c8bb7951682f430b9c5 274 Gene3D G3DSA:3.30.1050.10 187 265 1.3E-5 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS20320 3cb0f5589ee73c8bb7951682f430b9c5 274 SUPERFAMILY SSF55718 189 268 5.89E-6 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS20320 3cb0f5589ee73c8bb7951682f430b9c5 274 Pfam PF07398 MDMPI C-terminal domain 169 263 1.5E-10 T 23-04-2016 IPR010872 MDMPI C-terminal DC74_RS20320 3cb0f5589ee73c8bb7951682f430b9c5 274 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 17 153 1.9E-17 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS20320 3cb0f5589ee73c8bb7951682f430b9c5 274 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 244 1.7E-31 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS20320 3cb0f5589ee73c8bb7951682f430b9c5 274 Gene3D G3DSA:1.20.120.450 6 155 3.0E-7 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 SUPERFAMILY SSF50249 32 133 9.7E-22 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 PANTHER PTHR10724 22 370 3.7E-120 T 23-04-2016 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 Gene3D G3DSA:2.40.50.140 205 286 1.9E-30 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 SMART SM00316 37 108 1.9E-16 T 23-04-2016 IPR022967 RNA-binding domain, S1 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 SMART SM00316 210 280 1.3E-27 T 23-04-2016 IPR022967 RNA-binding domain, S1 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 SMART SM00316 124 191 6.5E-11 T 23-04-2016 IPR022967 RNA-binding domain, S1 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 SMART SM00316 295 366 1.1E-26 T 23-04-2016 IPR022967 RNA-binding domain, S1 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 Gene3D G3DSA:2.40.50.140 287 369 1.9E-29 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 PANTHER PTHR10724:SF6 22 370 3.7E-120 T 23-04-2016 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 SUPERFAMILY SSF50249 280 368 4.08E-26 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 Gene3D G3DSA:2.40.50.140 116 192 8.0E-16 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 Gene3D G3DSA:2.40.50.140 30 109 9.4E-18 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 PRINTS PR00681 Ribosomal protein S1 signature 39 57 4.3E-86 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 PRINTS PR00681 Ribosomal protein S1 signature 129 145 4.3E-86 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 PRINTS PR00681 Ribosomal protein S1 signature 57 71 4.3E-86 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 PRINTS PR00681 Ribosomal protein S1 signature 105 124 4.3E-86 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 PRINTS PR00681 Ribosomal protein S1 signature 232 253 4.3E-86 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 PRINTS PR00681 Ribosomal protein S1 signature 146 163 4.3E-86 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 PRINTS PR00681 Ribosomal protein S1 signature 310 329 4.3E-86 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 PRINTS PR00681 Ribosomal protein S1 signature 349 367 4.3E-86 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 PRINTS PR00681 Ribosomal protein S1 signature 175 195 4.3E-86 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 Pfam PF00575 S1 RNA binding domain 124 191 1.1E-13 T 23-04-2016 IPR003029 S1 domain GO:0003676 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 Pfam PF00575 S1 RNA binding domain 294 366 3.6E-23 T 23-04-2016 IPR003029 S1 domain GO:0003676 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 Pfam PF00575 S1 RNA binding domain 209 280 9.6E-26 T 23-04-2016 IPR003029 S1 domain GO:0003676 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 Pfam PF00575 S1 RNA binding domain 36 108 5.0E-15 T 23-04-2016 IPR003029 S1 domain GO:0003676 DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 SUPERFAMILY SSF50249 113 191 1.34E-14 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS12045 8a0e956e14fb5496c44d16459410859f 503 SUPERFAMILY SSF50249 210 292 3.29E-27 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS26695 d2d4f34585fda650234c8afed6e2dcde 250 SUPERFAMILY SSF53335 19 219 2.26E-20 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS26695 d2d4f34585fda650234c8afed6e2dcde 250 PANTHER PTHR11558 90 237 1.9E-41 T 23-04-2016 DC74_RS26695 d2d4f34585fda650234c8afed6e2dcde 250 Gene3D G3DSA:3.40.50.150 73 217 3.8E-20 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS26695 d2d4f34585fda650234c8afed6e2dcde 250 PANTHER PTHR11558:SF4 90 237 1.9E-41 T 23-04-2016 DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 PANTHER PTHR30294:SF25 532 735 3.6E-62 T 23-04-2016 DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 PANTHER PTHR30294:SF25 24 262 3.6E-62 T 23-04-2016 DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 SUPERFAMILY SSF58104 260 480 6.02E-6 T 23-04-2016 DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 5.5E-56 T 23-04-2016 IPR017500 Phage infection protein, YhgE, N-terminal DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 PANTHER PTHR30294 532 735 3.6E-62 T 23-04-2016 DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 PANTHER PTHR30294 24 262 3.6E-62 T 23-04-2016 DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 176 202 3.4E-4 T 23-04-2016 IPR023908 xxxLxxG heptad repeat DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 415 440 1.1E-5 T 23-04-2016 IPR023908 xxxLxxG heptad repeat DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 203 230 2.1E-4 T 23-04-2016 IPR023908 xxxLxxG heptad repeat DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 470 496 4.0E-5 T 23-04-2016 IPR023908 xxxLxxG heptad repeat DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 435 461 1.1E-6 T 23-04-2016 IPR023908 xxxLxxG heptad repeat DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 518 721 1.7E-68 T 23-04-2016 IPR017501 Phage infection protein, YhgE, C-terminal DC74_RS12625 a1b08664cb802054c70b3952bda26cdc 735 Pfam PF12698 ABC-2 family transporter protein 525 714 5.9E-13 T 23-04-2016 DC74_RS38420 6c192ef4463f2e1839f782bbdcf07513 221 Pfam PF07729 FCD domain 80 202 3.7E-20 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS38420 6c192ef4463f2e1839f782bbdcf07513 221 SUPERFAMILY SSF46785 3 73 5.45E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38420 6c192ef4463f2e1839f782bbdcf07513 221 SMART SM00895 79 203 9.1E-10 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS38420 6c192ef4463f2e1839f782bbdcf07513 221 SMART SM00345 11 69 1.4E-12 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS38420 6c192ef4463f2e1839f782bbdcf07513 221 SUPERFAMILY SSF48008 76 208 1.1E-20 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS38420 6c192ef4463f2e1839f782bbdcf07513 221 PANTHER PTHR11751 9 95 1.5E-18 T 23-04-2016 DC74_RS38420 6c192ef4463f2e1839f782bbdcf07513 221 Gene3D G3DSA:1.10.10.10 3 69 4.2E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38420 6c192ef4463f2e1839f782bbdcf07513 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 69 1.2E-14 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS38420 6c192ef4463f2e1839f782bbdcf07513 221 PANTHER PTHR11751:SF385 9 95 1.5E-18 T 23-04-2016 DC74_RS38420 6c192ef4463f2e1839f782bbdcf07513 221 Gene3D G3DSA:1.20.120.530 73 208 1.9E-22 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS15795 a22a23365df55d8a1ce0a7f4e627dec2 267 PANTHER PTHR12110:SF3 2 264 1.8E-47 T 23-04-2016 DC74_RS15795 a22a23365df55d8a1ce0a7f4e627dec2 267 PANTHER PTHR12110 2 264 1.8E-47 T 23-04-2016 DC74_RS15795 a22a23365df55d8a1ce0a7f4e627dec2 267 Gene3D G3DSA:3.20.20.150 3 261 1.4E-51 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS15795 a22a23365df55d8a1ce0a7f4e627dec2 267 SUPERFAMILY SSF51658 2 243 2.35E-39 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS15795 a22a23365df55d8a1ce0a7f4e627dec2 267 Pfam PF01261 Xylose isomerase-like TIM barrel 20 215 5.0E-28 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS02940 59bc592174df92eeac8a7a12494eb26e 144 PANTHER PTHR41294:SF1 2 137 1.3E-59 T 23-04-2016 DC74_RS02940 59bc592174df92eeac8a7a12494eb26e 144 Gene3D G3DSA:3.10.180.10 6 116 7.4E-24 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS02940 59bc592174df92eeac8a7a12494eb26e 144 PANTHER PTHR41294 2 137 1.3E-59 T 23-04-2016 DC74_RS02940 59bc592174df92eeac8a7a12494eb26e 144 SUPERFAMILY SSF54593 6 120 3.62E-19 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS02940 59bc592174df92eeac8a7a12494eb26e 144 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 86 1.6E-11 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS13455 b60387efa5a3731e1bd68ec858caea78 305 Gene3D G3DSA:3.10.310.10 21 144 5.5E-36 T 23-04-2016 DC74_RS13455 b60387efa5a3731e1bd68ec858caea78 305 PANTHER PTHR13774:SF21 9 297 1.8E-76 T 23-04-2016 DC74_RS13455 b60387efa5a3731e1bd68ec858caea78 305 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 19 300 3.7E-47 T 23-04-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- DC74_RS13455 b60387efa5a3731e1bd68ec858caea78 305 Gene3D G3DSA:3.10.310.10 145 287 5.6E-37 T 23-04-2016 DC74_RS13455 b60387efa5a3731e1bd68ec858caea78 305 SUPERFAMILY SSF54506 20 300 2.09E-55 T 23-04-2016 DC74_RS13455 b60387efa5a3731e1bd68ec858caea78 305 PIRSF PIRSF016184 16 304 8.0E-60 T 23-04-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- DC74_RS13455 b60387efa5a3731e1bd68ec858caea78 305 PANTHER PTHR13774 9 297 1.8E-76 T 23-04-2016 DC74_RS13455 b60387efa5a3731e1bd68ec858caea78 305 Pfam PF02567 Phenazine biosynthesis-like protein 25 300 8.4E-62 T 23-04-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 PANTHER PTHR13789:SF90 3 382 1.7E-71 T 23-04-2016 DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 Gene3D G3DSA:3.50.50.60 4 72 4.7E-43 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 Gene3D G3DSA:3.50.50.60 107 186 4.7E-43 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 Gene3D G3DSA:3.50.50.60 296 375 4.7E-43 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 SUPERFAMILY SSF51905 295 385 1.77E-44 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 SUPERFAMILY SSF51905 3 181 1.77E-44 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 Pfam PF01494 FAD binding domain 3 370 8.3E-48 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 PANTHER PTHR13789 3 382 1.7E-71 T 23-04-2016 DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 339 6.4E-30 T 23-04-2016 DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 6.4E-30 T 23-04-2016 DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 359 6.4E-30 T 23-04-2016 DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 160 175 6.4E-30 T 23-04-2016 DC74_RS28800 1b40886ea1c2204932e78b512b44741a 599 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 323 6.4E-30 T 23-04-2016 DC74_RS37300 e7ba63c61cebd4841a3e7a62ab2a4c46 366 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 17 366 44.35 T 23-04-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 DC74_RS37300 e7ba63c61cebd4841a3e7a62ab2a4c46 366 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 18 363 1.7E-128 T 23-04-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 DC74_RS37300 e7ba63c61cebd4841a3e7a62ab2a4c46 366 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 250 269 - T 23-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 DC74_RS37300 e7ba63c61cebd4841a3e7a62ab2a4c46 366 Gene3D G3DSA:3.40.718.10 18 356 6.9E-116 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS37300 e7ba63c61cebd4841a3e7a62ab2a4c46 366 SUPERFAMILY SSF53659 18 366 1.23E-107 T 23-04-2016 DC74_RS37300 e7ba63c61cebd4841a3e7a62ab2a4c46 366 PANTHER PTHR11835 18 366 1.3E-165 T 23-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 DC74_RS37300 e7ba63c61cebd4841a3e7a62ab2a4c46 366 PANTHER PTHR11835:SF35 18 366 1.3E-165 T 23-04-2016 DC74_RS37300 e7ba63c61cebd4841a3e7a62ab2a4c46 366 SMART SM01329 18 362 2.5E-163 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS37300 e7ba63c61cebd4841a3e7a62ab2a4c46 366 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 19 361 2.7E-115 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS30245 ac27373d6aed91f78d0cee18390ec3a5 325 PANTHER PTHR17490 2 324 1.6E-101 T 23-04-2016 DC74_RS30245 ac27373d6aed91f78d0cee18390ec3a5 325 PANTHER PTHR17490:SF3 2 324 1.6E-101 T 23-04-2016 DC74_RS30245 ac27373d6aed91f78d0cee18390ec3a5 325 Pfam PF03481 Putative GTP-binding controlling metal-binding 191 320 2.0E-22 T 23-04-2016 IPR005145 Putative GTP-binding controlling metal-binding domain DC74_RS30245 ac27373d6aed91f78d0cee18390ec3a5 325 Gene3D G3DSA:3.90.870.10 3 197 2.5E-77 T 23-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain DC74_RS30245 ac27373d6aed91f78d0cee18390ec3a5 325 Pfam PF01300 Telomere recombination 15 189 1.5E-57 T 23-04-2016 IPR006070 YrdC-like domain GO:0003725 DC74_RS30245 ac27373d6aed91f78d0cee18390ec3a5 325 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 4 200 5.5E-58 T 23-04-2016 IPR006070 YrdC-like domain GO:0003725 DC74_RS30245 ac27373d6aed91f78d0cee18390ec3a5 325 SUPERFAMILY SSF55821 7 200 8.85E-64 T 23-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain DC74_RS30245 ac27373d6aed91f78d0cee18390ec3a5 325 PIRSF PIRSF004930 1 325 7.8E-110 T 23-04-2016 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 DC74_RS05895 7a7f2006e9c0472d0e43b56fcd3c1184 154 Pfam PF13411 MerR HTH family regulatory protein 33 94 2.0E-14 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS05895 7a7f2006e9c0472d0e43b56fcd3c1184 154 ProSitePatterns PS00552 MerR-type HTH domain signature. 36 58 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS05895 7a7f2006e9c0472d0e43b56fcd3c1184 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 34 45 3.8E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS05895 7a7f2006e9c0472d0e43b56fcd3c1184 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 45 58 3.8E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS05895 7a7f2006e9c0472d0e43b56fcd3c1184 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 69 89 3.8E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS05895 7a7f2006e9c0472d0e43b56fcd3c1184 154 PANTHER PTHR30204 25 145 7.5E-57 T 23-04-2016 DC74_RS05895 7a7f2006e9c0472d0e43b56fcd3c1184 154 PANTHER PTHR30204:SF2 25 145 7.5E-57 T 23-04-2016 DC74_RS05895 7a7f2006e9c0472d0e43b56fcd3c1184 154 SUPERFAMILY SSF46955 33 144 1.72E-29 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS05895 7a7f2006e9c0472d0e43b56fcd3c1184 154 Gene3D G3DSA:1.10.1660.10 33 145 9.4E-31 T 23-04-2016 DC74_RS05895 7a7f2006e9c0472d0e43b56fcd3c1184 154 SMART SM00422 33 102 1.3E-16 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS13860 773eed66c387dfa31092151afc0aa560 166 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 122 1.1E-15 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS13860 773eed66c387dfa31092151afc0aa560 166 PANTHER PTHR10374:SF14 5 132 4.7E-18 T 23-04-2016 DC74_RS13860 773eed66c387dfa31092151afc0aa560 166 PANTHER PTHR10374 5 132 4.7E-18 T 23-04-2016 DC74_RS13860 773eed66c387dfa31092151afc0aa560 166 SUPERFAMILY SSF54593 1 137 1.32E-34 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS13860 773eed66c387dfa31092151afc0aa560 166 Gene3D G3DSA:3.10.180.10 3 132 8.0E-31 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS32085 e6641f9b10b7db29bb2e12fe4941cde9 409 Gene3D G3DSA:3.40.50.10540 2 214 4.2E-106 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS32085 e6641f9b10b7db29bb2e12fe4941cde9 409 Gene3D G3DSA:3.40.50.10540 319 409 4.2E-106 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS32085 e6641f9b10b7db29bb2e12fe4941cde9 409 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 3 409 4.9E-204 T 23-04-2016 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0008152|GO:0033608 MetaCyc: PWY-6695|UniPathway: UPA00540 DC74_RS32085 e6641f9b10b7db29bb2e12fe4941cde9 409 PANTHER PTHR24023:SF593 237 396 5.0E-28 T 23-04-2016 DC74_RS32085 e6641f9b10b7db29bb2e12fe4941cde9 409 PANTHER PTHR24023 237 396 5.0E-28 T 23-04-2016 DC74_RS32085 e6641f9b10b7db29bb2e12fe4941cde9 409 PANTHER PTHR24023 42 211 5.0E-28 T 23-04-2016 DC74_RS32085 e6641f9b10b7db29bb2e12fe4941cde9 409 SUPERFAMILY SSF89796 3 409 4.32E-122 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS32085 e6641f9b10b7db29bb2e12fe4941cde9 409 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 1 409 63.431 T 23-04-2016 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0008152|GO:0033608 MetaCyc: PWY-6695|UniPathway: UPA00540 DC74_RS32085 e6641f9b10b7db29bb2e12fe4941cde9 409 PANTHER PTHR24023:SF593 42 211 5.0E-28 T 23-04-2016 DC74_RS32085 e6641f9b10b7db29bb2e12fe4941cde9 409 Gene3D G3DSA:3.30.1540.10 234 318 2.9E-24 T 23-04-2016 DC74_RS32085 e6641f9b10b7db29bb2e12fe4941cde9 409 Pfam PF02515 CoA-transferase family III 5 385 1.3E-103 T 23-04-2016 IPR003673 CoA-transferase family III GO:0003824 DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 Gene3D G3DSA:1.10.40.30 405 464 3.1E-21 T 23-04-2016 DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 SUPERFAMILY SSF48557 7 463 3.14E-145 T 23-04-2016 IPR008948 L-Aspartase-like GO:0003824 DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 ProSitePatterns PS00163 Fumarate lyases signature. 314 323 - T 23-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 Pfam PF00206 Lyase 15 339 2.3E-103 T 23-04-2016 IPR022761 Fumarate lyase, N-terminal DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 Pfam PF10415 Fumarase C C-terminus 405 463 2.3E-20 T 23-04-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 PANTHER PTHR11444 1 464 3.9E-228 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 PRINTS PR00145 Argininosuccinate lyase family signature 314 330 2.6E-5 T 23-04-2016 DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 PRINTS PR00145 Argininosuccinate lyase family signature 172 192 2.6E-5 T 23-04-2016 DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 Gene3D G3DSA:1.10.275.10 7 135 1.1E-53 T 23-04-2016 IPR024083 Fumarase/histidase, N-terminal DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 Gene3D G3DSA:1.20.200.10 136 400 2.5E-95 T 23-04-2016 DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 PRINTS PR00149 Fumarate lyase superfamily signature 268 295 9.1E-33 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 PRINTS PR00149 Fumarate lyase superfamily signature 314 330 9.1E-33 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 PRINTS PR00149 Fumarate lyase superfamily signature 131 149 9.1E-33 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 PRINTS PR00149 Fumarate lyase superfamily signature 177 195 9.1E-33 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 PANTHER PTHR11444:SF1 1 464 3.9E-228 T 23-04-2016 DC74_RS25575 77f3078952bd1b612c9c015af7da1420 464 Hamap MF_00743 Fumarate hydratase class II [fumC]. 7 464 81.906 T 23-04-2016 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS38345 bd6404eb90b381dadd9f16a647ca0574 120 SUPERFAMILY SSF55331 2 115 1.83E-17 T 23-04-2016 IPR014347 Tautomerase/MIF superfamily DC74_RS38345 bd6404eb90b381dadd9f16a647ca0574 120 Gene3D G3DSA:3.30.429.10 2 117 4.3E-21 T 23-04-2016 DC74_RS38345 bd6404eb90b381dadd9f16a647ca0574 120 PANTHER PTHR37950 2 115 2.0E-16 T 23-04-2016 DC74_RS29700 f461518c393063a8ae580313bdc69bcd 317 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 215 278 4.4E-9 T 23-04-2016 DC74_RS29700 f461518c393063a8ae580313bdc69bcd 317 Gene3D G3DSA:2.130.10.130 173 306 2.0E-11 T 23-04-2016 DC74_RS29700 f461518c393063a8ae580313bdc69bcd 317 SUPERFAMILY SSF69318 83 310 1.44E-20 T 23-04-2016 DC74_RS21095 c7e4f83b67239d77632ffc4fdc28cf62 297 Pfam PF12679 ABC-2 family transporter protein 93 295 1.9E-7 T 23-04-2016 IPR032688 ABC-2 family transporter protein GO:0006810 DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 Gene3D G3DSA:3.40.50.720 2 205 7.9E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 1.4E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 1.4E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 1.4E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 1.4E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.4E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 Pfam PF00106 short chain dehydrogenase 7 182 5.0E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 PANTHER PTHR24322:SF546 143 175 1.9E-40 T 23-04-2016 DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 PANTHER PTHR24322:SF546 10 127 1.9E-40 T 23-04-2016 DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 SUPERFAMILY SSF51735 1 206 3.57E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 4.0E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 4.0E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 4.0E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 PANTHER PTHR24322 143 175 1.9E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04965 d504836f98f5e60134114324bf7f3491 228 PANTHER PTHR24322 10 127 1.9E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS32380 bbc573eaf1b7392a4781956a05abea5b 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 62 4.9E-18 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS32380 bbc573eaf1b7392a4781956a05abea5b 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS32380 bbc573eaf1b7392a4781956a05abea5b 193 Gene3D G3DSA:1.10.357.10 5 187 2.2E-29 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS32380 bbc573eaf1b7392a4781956a05abea5b 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.4E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS32380 bbc573eaf1b7392a4781956a05abea5b 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 5.4E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS32380 bbc573eaf1b7392a4781956a05abea5b 193 PANTHER PTHR30055 1 186 5.8E-29 T 23-04-2016 DC74_RS32380 bbc573eaf1b7392a4781956a05abea5b 193 PANTHER PTHR30055:SF11 1 186 5.8E-29 T 23-04-2016 DC74_RS32380 bbc573eaf1b7392a4781956a05abea5b 193 SUPERFAMILY SSF46689 7 83 3.49E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS19095 c44391d6a6b62785877c54c990c40536 233 PANTHER PTHR10108:SF24 12 229 8.6E-73 T 23-04-2016 DC74_RS19095 c44391d6a6b62785877c54c990c40536 233 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 229 33.952 T 23-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 DC74_RS19095 c44391d6a6b62785877c54c990c40536 233 SUPERFAMILY SSF53335 4 228 5.27E-44 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS19095 c44391d6a6b62785877c54c990c40536 233 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 229 1.4E-70 T 23-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 DC74_RS19095 c44391d6a6b62785877c54c990c40536 233 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 229 5.3E-60 T 23-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 DC74_RS19095 c44391d6a6b62785877c54c990c40536 233 PANTHER PTHR10108 12 229 8.6E-73 T 23-04-2016 DC74_RS19095 c44391d6a6b62785877c54c990c40536 233 Gene3D G3DSA:3.40.50.150 12 225 8.0E-45 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS19095 c44391d6a6b62785877c54c990c40536 233 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 137 151 - T 23-04-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 DC74_RS15005 e72d55e4e0c00eb8e6a9ffbb07ca773d 119 PANTHER PTHR23089:SF2 4 119 1.4E-46 T 23-04-2016 DC74_RS15005 e72d55e4e0c00eb8e6a9ffbb07ca773d 119 Pfam PF01230 HIT domain 17 112 6.5E-25 T 23-04-2016 IPR001310 Histidine triad (HIT) protein DC74_RS15005 e72d55e4e0c00eb8e6a9ffbb07ca773d 119 PRINTS PR00332 Histidine triad family signature 10 26 2.3E-19 T 23-04-2016 IPR001310 Histidine triad (HIT) protein DC74_RS15005 e72d55e4e0c00eb8e6a9ffbb07ca773d 119 PRINTS PR00332 Histidine triad family signature 31 49 2.3E-19 T 23-04-2016 IPR001310 Histidine triad (HIT) protein DC74_RS15005 e72d55e4e0c00eb8e6a9ffbb07ca773d 119 PRINTS PR00332 Histidine triad family signature 99 109 2.3E-19 T 23-04-2016 IPR001310 Histidine triad (HIT) protein DC74_RS15005 e72d55e4e0c00eb8e6a9ffbb07ca773d 119 SUPERFAMILY SSF54197 7 118 3.25E-34 T 23-04-2016 IPR011146 HIT-like domain GO:0003824 DC74_RS15005 e72d55e4e0c00eb8e6a9ffbb07ca773d 119 PANTHER PTHR23089 4 119 1.4E-46 T 23-04-2016 IPR001310 Histidine triad (HIT) protein DC74_RS15005 e72d55e4e0c00eb8e6a9ffbb07ca773d 119 Gene3D G3DSA:3.30.428.10 4 119 1.1E-37 T 23-04-2016 IPR011146 HIT-like domain GO:0003824 DC74_RS29095 fab4ba017b8e031a9cc2970298ff61ca 223 Gene3D G3DSA:3.30.60.20 144 174 9.9E-4 T 23-04-2016 DC74_RS29095 fab4ba017b8e031a9cc2970298ff61ca 223 Gene3D G3DSA:3.40.50.300 2 120 1.2E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29095 fab4ba017b8e031a9cc2970298ff61ca 223 SUPERFAMILY SSF57716 144 201 3.28E-7 T 23-04-2016 DC74_RS29095 fab4ba017b8e031a9cc2970298ff61ca 223 PIRSF PIRSF035805 1 211 9.6E-37 T 23-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 DC74_RS29095 fab4ba017b8e031a9cc2970298ff61ca 223 Pfam PF00265 Thymidine kinase 4 173 5.3E-23 T 23-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 DC74_RS29095 fab4ba017b8e031a9cc2970298ff61ca 223 Hamap MF_00124 Thymidine kinase [tdk]. 1 201 27.964 T 23-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 DC74_RS29095 fab4ba017b8e031a9cc2970298ff61ca 223 SUPERFAMILY SSF52540 1 139 1.68E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16945 67bb9bd67c60e629debe1e5b6b7d142e 314 SUPERFAMILY SSF161111 6 219 4.58E-38 T 23-04-2016 DC74_RS16945 67bb9bd67c60e629debe1e5b6b7d142e 314 Gene3D G3DSA:3.30.70.1350 220 298 1.4E-6 T 23-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain DC74_RS16945 67bb9bd67c60e629debe1e5b6b7d142e 314 Pfam PF01545 Cation efflux family 11 218 2.3E-34 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DC74_RS16945 67bb9bd67c60e629debe1e5b6b7d142e 314 Gene3D G3DSA:1.20.1510.10 8 218 2.0E-33 T 23-04-2016 IPR027469 Cation efflux protein transmembrane domain DC74_RS16945 67bb9bd67c60e629debe1e5b6b7d142e 314 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 292 8.8E-40 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DC74_RS16945 67bb9bd67c60e629debe1e5b6b7d142e 314 PANTHER PTHR13414 1 286 1.5E-90 T 23-04-2016 DC74_RS16945 67bb9bd67c60e629debe1e5b6b7d142e 314 SUPERFAMILY SSF160240 222 295 4.45E-8 T 23-04-2016 DC74_RS32815 6d02c608249eec7f65115712930ca8f9 489 Pfam PF00171 Aldehyde dehydrogenase family 10 476 3.7E-163 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS32815 6d02c608249eec7f65115712930ca8f9 489 PANTHER PTHR11699:SF164 3 488 1.1E-239 T 23-04-2016 DC74_RS32815 6d02c608249eec7f65115712930ca8f9 489 Gene3D G3DSA:3.40.605.10 3 262 8.4E-90 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS32815 6d02c608249eec7f65115712930ca8f9 489 SUPERFAMILY SSF53720 3 481 5.89E-160 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS32815 6d02c608249eec7f65115712930ca8f9 489 Gene3D G3DSA:3.40.309.10 263 442 9.8E-67 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS32815 6d02c608249eec7f65115712930ca8f9 489 PANTHER PTHR11699 3 488 1.1E-239 T 23-04-2016 DC74_RS32815 6d02c608249eec7f65115712930ca8f9 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS32815 6d02c608249eec7f65115712930ca8f9 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS40140 20349a61cd8057c5d3777cbe397f1318 339 SUPERFAMILY SSF50129 5 140 3.93E-20 T 23-04-2016 IPR011032 GroES-like DC74_RS40140 20349a61cd8057c5d3777cbe397f1318 339 Gene3D G3DSA:3.40.50.720 135 178 7.9E-11 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS40140 20349a61cd8057c5d3777cbe397f1318 339 PANTHER PTHR11695 8 174 3.3E-25 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS40140 20349a61cd8057c5d3777cbe397f1318 339 Gene3D G3DSA:3.90.180.10 9 134 9.4E-21 T 23-04-2016 IPR011032 GroES-like DC74_RS40140 20349a61cd8057c5d3777cbe397f1318 339 SUPERFAMILY SSF51735 110 232 2.78E-10 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS40140 20349a61cd8057c5d3777cbe397f1318 339 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 134 171 9.5E-6 T 23-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS12250 8e6a3aae2b1936728936c9c86bb34b25 193 Gene3D G3DSA:1.10.10.10 30 178 9.2E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS12250 8e6a3aae2b1936728936c9c86bb34b25 193 Pfam PF12802 MarR family 67 123 2.7E-11 T 23-04-2016 DC74_RS12250 8e6a3aae2b1936728936c9c86bb34b25 193 PANTHER PTHR33164 15 188 3.1E-19 T 23-04-2016 DC74_RS12250 8e6a3aae2b1936728936c9c86bb34b25 193 SMART SM00347 61 164 5.1E-10 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS12250 8e6a3aae2b1936728936c9c86bb34b25 193 SUPERFAMILY SSF46785 30 176 1.17E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25940 e08c807922791725d3e4044b04e8cd58 362 Pfam PF01546 Peptidase family M20/M25/M40 72 356 6.9E-21 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS25940 e08c807922791725d3e4044b04e8cd58 362 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 14 361 1.2E-158 T 23-04-2016 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18|UniPathway: UPA00034 DC74_RS25940 e08c807922791725d3e4044b04e8cd58 362 SUPERFAMILY SSF55031 173 273 2.99E-19 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS25940 e08c807922791725d3e4044b04e8cd58 362 Pfam PF07687 Peptidase dimerisation domain 173 271 6.4E-14 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS25940 e08c807922791725d3e4044b04e8cd58 362 SUPERFAMILY SSF53187 282 361 7.6E-42 T 23-04-2016 DC74_RS25940 e08c807922791725d3e4044b04e8cd58 362 SUPERFAMILY SSF53187 17 185 7.6E-42 T 23-04-2016 DC74_RS25940 e08c807922791725d3e4044b04e8cd58 362 Gene3D G3DSA:3.40.630.10 15 173 9.5E-45 T 23-04-2016 DC74_RS25940 e08c807922791725d3e4044b04e8cd58 362 Gene3D G3DSA:3.40.630.10 283 360 9.5E-45 T 23-04-2016 DC74_RS25940 e08c807922791725d3e4044b04e8cd58 362 PANTHER PTHR11014 17 347 1.7E-55 T 23-04-2016 DC74_RS25940 e08c807922791725d3e4044b04e8cd58 362 Gene3D G3DSA:3.30.70.360 174 272 7.3E-23 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS08735 0168e94aee43393fa30ff15ea0d7beb1 274 PANTHER PTHR14237 2 274 2.5E-82 T 23-04-2016 DC74_RS08735 0168e94aee43393fa30ff15ea0d7beb1 274 Pfam PF03473 MOSC domain 144 270 5.2E-30 T 23-04-2016 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 DC74_RS08735 0168e94aee43393fa30ff15ea0d7beb1 274 PANTHER PTHR14237:SF30 2 274 2.5E-82 T 23-04-2016 DC74_RS08735 0168e94aee43393fa30ff15ea0d7beb1 274 Pfam PF03476 MOSC N-terminal beta barrel domain 5 118 1.2E-25 T 23-04-2016 IPR005303 MOSC, N-terminal beta barrel DC74_RS08735 0168e94aee43393fa30ff15ea0d7beb1 274 SUPERFAMILY SSF50800 4 52 6.07E-16 T 23-04-2016 IPR011037 Pyruvate kinase-like, insert domain DC74_RS08735 0168e94aee43393fa30ff15ea0d7beb1 274 SUPERFAMILY SSF50800 153 273 6.07E-16 T 23-04-2016 IPR011037 Pyruvate kinase-like, insert domain DC74_RS08735 0168e94aee43393fa30ff15ea0d7beb1 274 SUPERFAMILY SSF141673 6 134 9.02E-32 T 23-04-2016 DC74_RS03590 67d857ffe6c52ea838746639007bc42c 392 Gene3D G3DSA:1.20.140.10 224 387 5.6E-61 T 23-04-2016 DC74_RS03590 67d857ffe6c52ea838746639007bc42c 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 3.0E-44 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS03590 67d857ffe6c52ea838746639007bc42c 392 Gene3D G3DSA:2.40.110.10 123 223 2.8E-31 T 23-04-2016 DC74_RS03590 67d857ffe6c52ea838746639007bc42c 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 222 2.8E-25 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS03590 67d857ffe6c52ea838746639007bc42c 392 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS03590 67d857ffe6c52ea838746639007bc42c 392 PIRSF PIRSF016578 14 389 1.2E-15 T 23-04-2016 DC74_RS03590 67d857ffe6c52ea838746639007bc42c 392 SUPERFAMILY SSF47203 235 387 8.22E-52 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS03590 67d857ffe6c52ea838746639007bc42c 392 Gene3D G3DSA:1.10.540.10 7 121 1.6E-34 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS03590 67d857ffe6c52ea838746639007bc42c 392 PANTHER PTHR10909 7 387 1.1E-197 T 23-04-2016 DC74_RS03590 67d857ffe6c52ea838746639007bc42c 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 119 5.9E-30 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS03590 67d857ffe6c52ea838746639007bc42c 392 PANTHER PTHR10909:SF311 7 387 1.1E-197 T 23-04-2016 DC74_RS03590 67d857ffe6c52ea838746639007bc42c 392 SUPERFAMILY SSF56645 7 248 6.28E-68 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS17850 d5513dec584eccbd5360637f63a54ca3 189 SUPERFAMILY SSF100950 38 187 5.58E-39 T 23-04-2016 DC74_RS17850 d5513dec584eccbd5360637f63a54ca3 189 Gene3D G3DSA:3.40.50.10420 2 187 5.6E-49 T 23-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain DC74_RS17850 d5513dec584eccbd5360637f63a54ca3 189 PANTHER PTHR23407:SF1 1 188 1.5E-40 T 23-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase DC74_RS17850 d5513dec584eccbd5360637f63a54ca3 189 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 38 181 1.0E-37 T 23-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase DC74_RS17850 d5513dec584eccbd5360637f63a54ca3 189 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 37 181 1.8E-36 T 23-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase DC74_RS17850 d5513dec584eccbd5360637f63a54ca3 189 PANTHER PTHR23407 1 188 1.5E-40 T 23-04-2016 DC74_RS36495 aeb8324f9a16a02b118a0a1ea91ceacb 472 Gene3D G3DSA:1.25.40.10 159 212 1.1E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS36495 aeb8324f9a16a02b118a0a1ea91ceacb 472 Gene3D G3DSA:1.25.40.10 17 27 1.1E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS36495 aeb8324f9a16a02b118a0a1ea91ceacb 472 Gene3D G3DSA:1.25.40.10 417 462 1.1E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS36495 aeb8324f9a16a02b118a0a1ea91ceacb 472 SUPERFAMILY SSF48452 157 213 3.97E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS36495 aeb8324f9a16a02b118a0a1ea91ceacb 472 SUPERFAMILY SSF48452 407 458 3.97E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS36495 aeb8324f9a16a02b118a0a1ea91ceacb 472 PANTHER PTHR16263 35 470 2.5E-91 T 23-04-2016 DC74_RS32970 e3b7c271f6d58ff675061bb5918f364b 301 PANTHER PTHR10937 36 296 4.0E-27 T 23-04-2016 DC74_RS32970 e3b7c271f6d58ff675061bb5918f364b 301 Pfam PF01380 SIS domain 36 145 8.6E-6 T 23-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 DC74_RS32970 e3b7c271f6d58ff675061bb5918f364b 301 Gene3D G3DSA:3.40.50.10490 5 152 3.9E-18 T 23-04-2016 DC74_RS32970 e3b7c271f6d58ff675061bb5918f364b 301 Gene3D G3DSA:3.40.50.10490 162 241 8.9E-21 T 23-04-2016 DC74_RS32970 e3b7c271f6d58ff675061bb5918f364b 301 Gene3D G3DSA:3.40.50.10490 258 293 1.0E-6 T 23-04-2016 DC74_RS32970 e3b7c271f6d58ff675061bb5918f364b 301 SUPERFAMILY SSF53697 5 294 1.44E-42 T 23-04-2016 DC74_RS32970 e3b7c271f6d58ff675061bb5918f364b 301 PANTHER PTHR10937:SF4 36 296 4.0E-27 T 23-04-2016 DC74_RS26445 882900990d883d3be3cf2a892365025a 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 263 2.2E-22 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26445 882900990d883d3be3cf2a892365025a 276 PANTHER PTHR32243:SF42 1 276 8.3E-134 T 23-04-2016 DC74_RS26445 882900990d883d3be3cf2a892365025a 276 Gene3D G3DSA:1.10.3720.10 5 263 5.5E-64 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26445 882900990d883d3be3cf2a892365025a 276 SUPERFAMILY SSF161098 2 276 1.96E-70 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26445 882900990d883d3be3cf2a892365025a 276 PANTHER PTHR32243 1 276 8.3E-134 T 23-04-2016 DC74_RS05255 1232c4f114de40f7f31d2dda7722ed2d 349 Gene3D G3DSA:3.30.390.10 3 120 1.6E-17 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS05255 1232c4f114de40f7f31d2dda7722ed2d 349 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 182 213 - T 23-04-2016 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 DC74_RS05255 1232c4f114de40f7f31d2dda7722ed2d 349 SMART SM00922 136 232 3.6E-19 T 23-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DC74_RS05255 1232c4f114de40f7f31d2dda7722ed2d 349 SUPERFAMILY SSF54826 2 118 2.53E-18 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS05255 1232c4f114de40f7f31d2dda7722ed2d 349 Gene3D G3DSA:3.20.20.120 121 341 1.3E-59 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS05255 1232c4f114de40f7f31d2dda7722ed2d 349 SUPERFAMILY SSF51604 106 341 3.41E-54 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS05255 1232c4f114de40f7f31d2dda7722ed2d 349 PANTHER PTHR13794 1 341 5.5E-75 T 23-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 DC74_RS05255 1232c4f114de40f7f31d2dda7722ed2d 349 Pfam PF13378 Enolase C-terminal domain-like 142 341 1.7E-36 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS05255 1232c4f114de40f7f31d2dda7722ed2d 349 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 6 118 9.5E-11 T 23-04-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain DC74_RS05255 1232c4f114de40f7f31d2dda7722ed2d 349 PANTHER PTHR13794:SF60 1 341 5.5E-75 T 23-04-2016 DC74_RS21410 31c81bdc6f9d31ba74b028e24badb1db 550 PANTHER PTHR24096:SF53 3 539 2.3E-255 T 23-04-2016 DC74_RS21410 31c81bdc6f9d31ba74b028e24badb1db 550 Gene3D G3DSA:3.40.50.980 190 342 2.5E-35 T 23-04-2016 DC74_RS21410 31c81bdc6f9d31ba74b028e24badb1db 550 Gene3D G3DSA:3.30.300.30 440 539 2.1E-30 T 23-04-2016 DC74_RS21410 31c81bdc6f9d31ba74b028e24badb1db 550 Gene3D G3DSA:3.40.50.980 14 189 2.6E-30 T 23-04-2016 DC74_RS21410 31c81bdc6f9d31ba74b028e24badb1db 550 Gene3D G3DSA:2.30.38.10 358 439 1.7E-17 T 23-04-2016 DC74_RS21410 31c81bdc6f9d31ba74b028e24badb1db 550 Pfam PF00501 AMP-binding enzyme 31 445 3.1E-87 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS21410 31c81bdc6f9d31ba74b028e24badb1db 550 SUPERFAMILY SSF56801 8 541 1.31E-138 T 23-04-2016 DC74_RS21410 31c81bdc6f9d31ba74b028e24badb1db 550 PANTHER PTHR24096 3 539 2.3E-255 T 23-04-2016 DC74_RS21410 31c81bdc6f9d31ba74b028e24badb1db 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 529 6.4E-19 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS21410 31c81bdc6f9d31ba74b028e24badb1db 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS23395 d0ed09db323919b1320fda342c5b7424 290 PANTHER PTHR11732:SF136 10 290 1.5E-143 T 23-04-2016 DC74_RS23395 d0ed09db323919b1320fda342c5b7424 290 PRINTS PR00069 Aldo-keto reductase signature 117 135 5.1E-9 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS23395 d0ed09db323919b1320fda342c5b7424 290 PRINTS PR00069 Aldo-keto reductase signature 52 76 5.1E-9 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS23395 d0ed09db323919b1320fda342c5b7424 290 PRINTS PR00069 Aldo-keto reductase signature 152 169 5.1E-9 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS23395 d0ed09db323919b1320fda342c5b7424 290 PRINTS PR00069 Aldo-keto reductase signature 222 246 5.1E-9 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS23395 d0ed09db323919b1320fda342c5b7424 290 SUPERFAMILY SSF51430 17 288 7.73E-68 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS23395 d0ed09db323919b1320fda342c5b7424 290 Pfam PF00248 Aldo/keto reductase family 24 288 9.0E-50 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS23395 d0ed09db323919b1320fda342c5b7424 290 PANTHER PTHR11732 10 290 1.5E-143 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS23395 d0ed09db323919b1320fda342c5b7424 290 Gene3D G3DSA:3.20.20.100 17 288 2.1E-65 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS16385 ceaf341656e0743b1f1f8d1335fea627 141 SMART SM00232 1 134 2.0E-27 T 23-04-2016 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 DC74_RS16385 ceaf341656e0743b1f1f8d1335fea627 141 Gene3D G3DSA:3.40.140.10 1 136 3.2E-35 T 23-04-2016 DC74_RS16385 ceaf341656e0743b1f1f8d1335fea627 141 SUPERFAMILY SSF102712 1 133 5.23E-28 T 23-04-2016 DC74_RS16385 ceaf341656e0743b1f1f8d1335fea627 141 PANTHER PTHR34858:SF1 1 110 3.8E-41 T 23-04-2016 DC74_RS16385 ceaf341656e0743b1f1f8d1335fea627 141 Pfam PF14464 Prokaryotic homologs of the JAB domain 6 112 2.8E-27 T 23-04-2016 IPR028090 JAB domain, prokaryotic DC74_RS16385 ceaf341656e0743b1f1f8d1335fea627 141 PANTHER PTHR34858 1 110 3.8E-41 T 23-04-2016 DC74_RS34875 014f5f0c6ba6c4a0dc527211bf15f3b1 137 Pfam PF01479 S4 domain 11 56 9.7E-11 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS34875 014f5f0c6ba6c4a0dc527211bf15f3b1 137 SUPERFAMILY SSF55174 8 94 8.24E-24 T 23-04-2016 DC74_RS34875 014f5f0c6ba6c4a0dc527211bf15f3b1 137 PIRSF PIRSF016821 7 129 1.6E-44 T 23-04-2016 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 DC74_RS34875 014f5f0c6ba6c4a0dc527211bf15f3b1 137 SMART SM00363 10 74 7.5E-9 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS34875 014f5f0c6ba6c4a0dc527211bf15f3b1 137 Gene3D G3DSA:3.10.290.10 7 102 4.6E-30 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS27615 d5a7308cf8ac6e9978c8efb0ada3641c 334 SUPERFAMILY SSF51430 2 315 1.11E-95 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS27615 d5a7308cf8ac6e9978c8efb0ada3641c 334 PANTHER PTHR11732:SF225 1 315 1.5E-132 T 23-04-2016 DC74_RS27615 d5a7308cf8ac6e9978c8efb0ada3641c 334 Gene3D G3DSA:3.20.20.100 2 325 1.3E-105 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS27615 d5a7308cf8ac6e9978c8efb0ada3641c 334 PANTHER PTHR11732 1 315 1.5E-132 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS27615 d5a7308cf8ac6e9978c8efb0ada3641c 334 Pfam PF00248 Aldo/keto reductase family 16 313 2.1E-72 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 SUPERFAMILY SSF81665 671 871 1.57E-66 T 23-04-2016 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 SUPERFAMILY SSF81665 249 343 1.57E-66 T 23-04-2016 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 SUPERFAMILY SSF81665 26 132 1.57E-66 T 23-04-2016 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 Pfam PF00690 Cation transporter/ATPase, N-terminus 24 89 3.2E-14 T 23-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 351 357 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 PRINTS PR01836 Magnesium-transporting ATPase signature 698 709 5.0E-27 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 PRINTS PR01836 Magnesium-transporting ATPase signature 835 856 5.0E-27 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 PRINTS PR01836 Magnesium-transporting ATPase signature 786 807 5.0E-27 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 PRINTS PR01836 Magnesium-transporting ATPase signature 680 695 5.0E-27 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 PRINTS PR01836 Magnesium-transporting ATPase signature 278 297 5.0E-27 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 PRINTS PR01836 Magnesium-transporting ATPase signature 750 766 5.0E-27 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 PRINTS PR01836 Magnesium-transporting ATPase signature 261 277 5.0E-27 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 SMART SM00831 21 94 2.7E-15 T 23-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 SUPERFAMILY SSF56784 347 367 3.94E-34 T 23-04-2016 IPR023214 HAD-like domain DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 SUPERFAMILY SSF56784 478 722 3.94E-34 T 23-04-2016 IPR023214 HAD-like domain DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 PANTHER PTHR24093:SF128 23 880 1.2E-189 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 Gene3D G3DSA:3.40.1110.10 342 528 2.0E-25 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 594 711 1.2E-22 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 PANTHER PTHR24093 23 880 1.2E-189 T 23-04-2016 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 SUPERFAMILY SSF81660 355 530 3.53E-24 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 Pfam PF00122 E1-E2 ATPase 100 339 9.5E-42 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 28 877 3.9E-201 T 23-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 Gene3D G3DSA:2.70.150.10 39 73 1.8E-34 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 Gene3D G3DSA:2.70.150.10 127 243 1.8E-34 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 Pfam PF00702 haloacid dehalogenase-like hydrolase 345 636 5.0E-13 T 23-04-2016 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 SUPERFAMILY SSF81653 147 244 5.23E-23 T 23-04-2016 DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 Gene3D G3DSA:1.20.1110.10 74 126 7.5E-51 T 23-04-2016 IPR023298 P-type ATPase, transmembrane domain DC74_RS36665 56447654dacc03e8a2fa961ca4b5c463 889 Gene3D G3DSA:1.20.1110.10 591 862 7.5E-51 T 23-04-2016 IPR023298 P-type ATPase, transmembrane domain DC74_RS18190 9fd99f4a36384ee26f3d9de292f03d28 377 Pfam PF00296 Luciferase-like monooxygenase 9 329 2.0E-42 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS18190 9fd99f4a36384ee26f3d9de292f03d28 377 SUPERFAMILY SSF51679 1 358 4.45E-65 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS18190 9fd99f4a36384ee26f3d9de292f03d28 377 PANTHER PTHR30137 1 369 3.1E-46 T 23-04-2016 DC74_RS18190 9fd99f4a36384ee26f3d9de292f03d28 377 Gene3D G3DSA:3.20.20.30 1 366 1.4E-75 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS22165 610ecdc7ec0541a8691692efd5e93573 802 PANTHER PTHR31998 14 742 0.0 T 23-04-2016 DC74_RS22165 610ecdc7ec0541a8691692efd5e93573 802 PANTHER PTHR31998:SF0 14 742 0.0 T 23-04-2016 DC74_RS22165 610ecdc7ec0541a8691692efd5e93573 802 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 26 741 24.424 T 23-04-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 DC74_RS22165 610ecdc7ec0541a8691692efd5e93573 802 Pfam PF03030 Inorganic H+ pyrophosphatase 38 736 6.6E-237 T 23-04-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 DC74_RS22165 610ecdc7ec0541a8691692efd5e93573 802 PIRSF PIRSF001265 21 750 2.7E-260 T 23-04-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 DC74_RS22165 610ecdc7ec0541a8691692efd5e93573 802 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 30 742 8.7E-202 T 23-04-2016 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1 DC74_RS10365 95135c68d5409d254b5a440c723a2011 531 PIRSF PIRSF002741 9 523 4.1E-57 T 23-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DC74_RS10365 95135c68d5409d254b5a440c723a2011 531 PANTHER PTHR30290 1 525 7.6E-129 T 23-04-2016 DC74_RS10365 95135c68d5409d254b5a440c723a2011 531 Gene3D G3DSA:3.90.76.10 50 204 1.5E-31 T 23-04-2016 DC74_RS10365 95135c68d5409d254b5a440c723a2011 531 PANTHER PTHR30290:SF7 1 525 7.6E-129 T 23-04-2016 DC74_RS10365 95135c68d5409d254b5a440c723a2011 531 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 445 5.9E-68 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain DC74_RS10365 95135c68d5409d254b5a440c723a2011 531 SUPERFAMILY SSF53850 35 525 5.27E-95 T 23-04-2016 DC74_RS10365 95135c68d5409d254b5a440c723a2011 531 Gene3D G3DSA:3.10.105.10 284 497 1.1E-41 T 23-04-2016 DC74_RS16570 5d3f260c4450df46570ab1ccf9854a5b 298 Gene3D G3DSA:3.30.465.10 62 175 6.7E-26 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS16570 5d3f260c4450df46570ab1ccf9854a5b 298 PANTHER PTHR11908 15 260 2.5E-35 T 23-04-2016 DC74_RS16570 5d3f260c4450df46570ab1ccf9854a5b 298 Gene3D G3DSA:3.30.390.50 182 270 1.4E-4 T 23-04-2016 DC74_RS16570 5d3f260c4450df46570ab1ccf9854a5b 298 PANTHER PTHR11908:SF68 15 260 2.5E-35 T 23-04-2016 DC74_RS16570 5d3f260c4450df46570ab1ccf9854a5b 298 Gene3D G3DSA:3.30.43.10 15 55 6.6E-8 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS16570 5d3f260c4450df46570ab1ccf9854a5b 298 SUPERFAMILY SSF56176 11 175 1.73E-37 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS16570 5d3f260c4450df46570ab1ccf9854a5b 298 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 12 175 2.0E-38 T 23-04-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DC74_RS20560 050ca6a606269ac54e57e72a256ba5d7 465 PANTHER PTHR30474 57 461 2.0E-197 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 DC74_RS20560 050ca6a606269ac54e57e72a256ba5d7 465 PANTHER PTHR30474:SF3 57 461 2.0E-197 T 23-04-2016 DC74_RS20560 050ca6a606269ac54e57e72a256ba5d7 465 Pfam PF01098 Cell cycle protein 82 444 1.5E-70 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 DC74_RS23965 a215c7270d5f89c6ac1fdc5ce90899ff 446 Pfam PF13458 Periplasmic binding protein 61 400 1.0E-21 T 23-04-2016 IPR028081 Leucine-binding protein domain DC74_RS23965 a215c7270d5f89c6ac1fdc5ce90899ff 446 Gene3D G3DSA:3.40.50.2300 45 166 2.7E-17 T 23-04-2016 DC74_RS23965 a215c7270d5f89c6ac1fdc5ce90899ff 446 Gene3D G3DSA:3.40.50.2300 327 399 2.7E-17 T 23-04-2016 DC74_RS23965 a215c7270d5f89c6ac1fdc5ce90899ff 446 SUPERFAMILY SSF53822 57 406 1.37E-21 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS23965 a215c7270d5f89c6ac1fdc5ce90899ff 446 PANTHER PTHR30483:SF20 1 429 1.0E-63 T 23-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 DC74_RS23965 a215c7270d5f89c6ac1fdc5ce90899ff 446 PANTHER PTHR30483 1 429 1.0E-63 T 23-04-2016 DC74_RS23235 cb6749e200bbd03ec6b0641def189b4c 312 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 15 310 36.087 T 23-04-2016 IPR017813 Mycothiol acetyltransferase GO:0016747 DC74_RS23235 cb6749e200bbd03ec6b0641def189b4c 312 SUPERFAMILY SSF55729 18 308 2.4E-47 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS23235 cb6749e200bbd03ec6b0641def189b4c 312 PANTHER PTHR23091:SF235 140 309 3.3E-57 T 23-04-2016 DC74_RS23235 cb6749e200bbd03ec6b0641def189b4c 312 Pfam PF00583 Acetyltransferase (GNAT) family 222 299 5.5E-13 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS23235 cb6749e200bbd03ec6b0641def189b4c 312 Pfam PF00583 Acetyltransferase (GNAT) family 73 141 1.1E-5 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS23235 cb6749e200bbd03ec6b0641def189b4c 312 Gene3D G3DSA:3.40.630.30 168 308 3.7E-33 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS23235 cb6749e200bbd03ec6b0641def189b4c 312 PANTHER PTHR23091 140 309 3.3E-57 T 23-04-2016 DC74_RS23235 cb6749e200bbd03ec6b0641def189b4c 312 Gene3D G3DSA:3.40.630.30 20 141 5.4E-11 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS23235 cb6749e200bbd03ec6b0641def189b4c 312 PIRSF PIRSF021524 9 312 1.2E-110 T 23-04-2016 IPR017813 Mycothiol acetyltransferase GO:0016747 DC74_RS23235 cb6749e200bbd03ec6b0641def189b4c 312 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 20 308 1.4E-116 T 23-04-2016 IPR017813 Mycothiol acetyltransferase GO:0016747 DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 Pfam PF07690 Major Facilitator Superfamily 13 401 1.0E-46 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 Gene3D G3DSA:1.20.1250.20 8 189 2.6E-25 T 23-04-2016 DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 PANTHER PTHR23501:SF7 5 495 8.2E-130 T 23-04-2016 DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 Gene3D G3DSA:1.20.1250.20 470 498 1.6E-21 T 23-04-2016 DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 Gene3D G3DSA:1.20.1250.20 251 413 1.6E-21 T 23-04-2016 DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 10 34 4.4E-5 T 23-04-2016 DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 101 121 4.4E-5 T 23-04-2016 DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 4.4E-5 T 23-04-2016 DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 ProSitePatterns PS00216 Sugar transport proteins signature 1. 61 77 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 PANTHER PTHR23501 5 495 8.2E-130 T 23-04-2016 DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 6 488 4.2E-77 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 SUPERFAMILY SSF103473 8 196 1.05E-62 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 SUPERFAMILY SSF103473 469 503 1.05E-62 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS39755 10f7fc187542b7a79de588927ed10132 515 SUPERFAMILY SSF103473 242 412 1.05E-62 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 SUPERFAMILY SSF55961 175 381 4.16E-42 T 23-04-2016 DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 Gene3D G3DSA:3.90.380.10 153 376 2.8E-17 T 23-04-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 PANTHER PTHR21266 22 376 5.3E-79 T 23-04-2016 DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 Pfam PF00355 Rieske [2Fe-2S] domain 46 131 8.6E-19 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 SUPERFAMILY SSF50022 22 159 2.36E-45 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 PANTHER PTHR21266:SF2 22 376 5.3E-79 T 23-04-2016 DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 60 75 1.2E-22 T 23-04-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 103 123 1.2E-22 T 23-04-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 81 101 1.2E-22 T 23-04-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 188 210 1.2E-22 T 23-04-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 30 55 1.2E-22 T 23-04-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 Gene3D G3DSA:2.102.10.10 44 152 3.6E-37 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS06680 129d752ab513cbcdfd78afcd63125630 385 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 188 381 2.7E-43 T 23-04-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 DC74_RS10430 364cbfe697cac50ebec32120c09c53ec 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 305 9.7E-43 T 23-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 DC74_RS10430 364cbfe697cac50ebec32120c09c53ec 317 PANTHER PTHR32196 3 316 5.4E-64 T 23-04-2016 DC74_RS10430 364cbfe697cac50ebec32120c09c53ec 317 PANTHER PTHR32196:SF21 3 316 5.4E-64 T 23-04-2016 DC74_RS05110 d3f21fd982bc6bc47e8733f9de6875c5 292 Pfam PF04542 Sigma-70 region 2 11 76 7.4E-15 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS05110 d3f21fd982bc6bc47e8733f9de6875c5 292 Gene3D G3DSA:3.10.450.50 172 281 2.5E-9 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS05110 d3f21fd982bc6bc47e8733f9de6875c5 292 SUPERFAMILY SSF54427 176 285 1.06E-13 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS05110 d3f21fd982bc6bc47e8733f9de6875c5 292 SUPERFAMILY SSF88946 5 92 2.63E-17 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS05110 d3f21fd982bc6bc47e8733f9de6875c5 292 Gene3D G3DSA:1.10.1740.10 7 99 3.4E-17 T 23-04-2016 DC74_RS05110 d3f21fd982bc6bc47e8733f9de6875c5 292 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 161 2.3E-20 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS05110 d3f21fd982bc6bc47e8733f9de6875c5 292 PANTHER PTHR30173 3 283 1.0E-91 T 23-04-2016 DC74_RS05110 d3f21fd982bc6bc47e8733f9de6875c5 292 PANTHER PTHR30173:SF11 3 283 1.0E-91 T 23-04-2016 DC74_RS05110 d3f21fd982bc6bc47e8733f9de6875c5 292 SUPERFAMILY SSF88659 101 161 2.24E-10 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS05110 d3f21fd982bc6bc47e8733f9de6875c5 292 Gene3D G3DSA:1.10.10.10 104 161 1.4E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05110 d3f21fd982bc6bc47e8733f9de6875c5 292 Pfam PF08281 Sigma-70, region 4 109 160 3.3E-10 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21470 244d4fd0d2ba9f17b45f1c9da64ec819 352 Pfam PF01965 DJ-1/PfpI family 125 200 2.3E-10 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS21470 244d4fd0d2ba9f17b45f1c9da64ec819 352 Gene3D G3DSA:3.40.50.880 26 248 2.0E-45 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS21470 244d4fd0d2ba9f17b45f1c9da64ec819 352 SUPERFAMILY SSF52317 25 222 4.82E-41 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS21470 244d4fd0d2ba9f17b45f1c9da64ec819 352 PANTHER PTHR11019 17 347 4.8E-101 T 23-04-2016 DC74_RS21470 244d4fd0d2ba9f17b45f1c9da64ec819 352 SUPERFAMILY SSF46689 293 343 4.62E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS21470 244d4fd0d2ba9f17b45f1c9da64ec819 352 PANTHER PTHR11019:SF68 17 347 4.8E-101 T 23-04-2016 DC74_RS21470 244d4fd0d2ba9f17b45f1c9da64ec819 352 Gene3D G3DSA:1.10.10.60 295 341 1.5E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS21470 244d4fd0d2ba9f17b45f1c9da64ec819 352 SMART SM00342 256 339 2.1E-27 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS21470 244d4fd0d2ba9f17b45f1c9da64ec819 352 SUPERFAMILY SSF46689 244 290 1.57E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS21470 244d4fd0d2ba9f17b45f1c9da64ec819 352 Pfam PF12833 Helix-turn-helix domain 262 340 1.4E-21 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS21470 244d4fd0d2ba9f17b45f1c9da64ec819 352 Gene3D G3DSA:1.10.10.60 249 294 8.5E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS12295 1bd8bf00b297d7c31a335d4c9a1d28dd 286 Pfam PF00290 Tryptophan synthase alpha chain 18 268 3.3E-75 T 23-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS12295 1bd8bf00b297d7c31a335d4c9a1d28dd 286 Gene3D G3DSA:3.20.20.70 15 280 6.7E-91 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS12295 1bd8bf00b297d7c31a335d4c9a1d28dd 286 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 24 277 33.376 T 23-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS12295 1bd8bf00b297d7c31a335d4c9a1d28dd 286 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 58 71 - T 23-04-2016 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS12295 1bd8bf00b297d7c31a335d4c9a1d28dd 286 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 20 274 3.0E-66 T 23-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS12295 1bd8bf00b297d7c31a335d4c9a1d28dd 286 SUPERFAMILY SSF51366 14 254 1.65E-77 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 DC74_RS36890 d049d7c7adad609af0899884ff670365 259 Gene3D G3DSA:3.30.470.10 4 106 2.9E-7 T 23-04-2016 DC74_RS36890 d049d7c7adad609af0899884ff670365 259 Gene3D G3DSA:3.20.10.10 114 254 2.2E-18 T 23-04-2016 DC74_RS36890 d049d7c7adad609af0899884ff670365 259 Pfam PF01063 Amino-transferase class IV 23 231 9.2E-27 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS36890 d049d7c7adad609af0899884ff670365 259 SUPERFAMILY SSF56752 11 242 4.32E-39 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS18675 0f970d164724ba0b3b23775cda458b9a 186 ProSitePatterns PS00358 Ribosomal protein L5 signature. 63 79 - T 23-04-2016 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18675 0f970d164724ba0b3b23775cda458b9a 186 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 7 185 43.71 T 23-04-2016 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18675 0f970d164724ba0b3b23775cda458b9a 186 SUPERFAMILY SSF55282 9 184 1.2E-75 T 23-04-2016 IPR022803 Ribosomal protein L5 domain DC74_RS18675 0f970d164724ba0b3b23775cda458b9a 186 PIRSF PIRSF002161 3 186 2.1E-64 T 23-04-2016 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 DC74_RS18675 0f970d164724ba0b3b23775cda458b9a 186 Pfam PF00281 Ribosomal protein L5 30 86 2.4E-28 T 23-04-2016 IPR031310 Ribosomal protein L5, N-terminal DC74_RS18675 0f970d164724ba0b3b23775cda458b9a 186 PANTHER PTHR11994 8 185 1.4E-93 T 23-04-2016 DC74_RS18675 0f970d164724ba0b3b23775cda458b9a 186 Pfam PF00673 ribosomal L5P family C-terminus 90 183 1.9E-39 T 23-04-2016 IPR031309 Ribosomal protein L5, C-terminal DC74_RS18675 0f970d164724ba0b3b23775cda458b9a 186 Gene3D G3DSA:3.30.1440.10 8 184 2.7E-76 T 23-04-2016 IPR022803 Ribosomal protein L5 domain DC74_RS17120 3c7a9e55b571b9b95e1cd98a90ddd35d 392 PANTHER PTHR30349 249 386 1.4E-32 T 23-04-2016 DC74_RS17120 3c7a9e55b571b9b95e1cd98a90ddd35d 392 PANTHER PTHR30349 68 233 1.4E-32 T 23-04-2016 DC74_RS17120 3c7a9e55b571b9b95e1cd98a90ddd35d 392 PANTHER PTHR30349:SF20 68 233 1.4E-32 T 23-04-2016 DC74_RS17120 3c7a9e55b571b9b95e1cd98a90ddd35d 392 Gene3D G3DSA:1.10.443.10 176 361 7.1E-27 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS17120 3c7a9e55b571b9b95e1cd98a90ddd35d 392 Pfam PF00589 Phage integrase family 175 358 1.5E-20 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS17120 3c7a9e55b571b9b95e1cd98a90ddd35d 392 SUPERFAMILY SSF56349 64 362 2.5E-47 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DC74_RS17120 3c7a9e55b571b9b95e1cd98a90ddd35d 392 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 68 138 2.8E-6 T 23-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 DC74_RS17120 3c7a9e55b571b9b95e1cd98a90ddd35d 392 PANTHER PTHR30349:SF20 249 386 1.4E-32 T 23-04-2016 DC74_RS17120 3c7a9e55b571b9b95e1cd98a90ddd35d 392 Gene3D G3DSA:1.10.150.130 67 161 1.7E-12 T 23-04-2016 IPR023109 Integrase/recombinase, N-terminal DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 Gene3D G3DSA:3.60.21.10 43 390 5.3E-75 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 PRINTS PR01607 Apyrase family signature 460 483 3.76E-17 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 PRINTS PR01607 Apyrase family signature 294 317 3.76E-17 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 PRINTS PR01607 Apyrase family signature 536 555 3.76E-17 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 PRINTS PR01607 Apyrase family signature 48 66 3.76E-17 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 SUPERFAMILY SSF56300 43 391 4.91E-66 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 PANTHER PTHR11575 292 603 2.2E-135 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 PANTHER PTHR11575 42 271 2.2E-135 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 PANTHER PTHR11575:SF7 292 603 2.2E-135 T 23-04-2016 DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 PANTHER PTHR11575:SF7 42 271 2.2E-135 T 23-04-2016 DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 SUPERFAMILY SSF55816 392 602 4.71E-48 T 23-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 Gene3D G3DSA:3.90.780.10 394 602 1.5E-50 T 23-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 DC74_RS23230 8d6bc1d5dc4e80ea6f91c9b9310d79b4 603 Pfam PF02872 5'-nucleotidase, C-terminal domain 395 562 7.9E-39 T 23-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 DC74_RS35335 bb0f3a4f761414b9e2dd40a348d2a205 296 PANTHER PTHR30011 21 287 4.8E-39 T 23-04-2016 DC74_RS35335 bb0f3a4f761414b9e2dd40a348d2a205 296 SUPERFAMILY SSF51679 4 293 1.09E-51 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS35335 bb0f3a4f761414b9e2dd40a348d2a205 296 PANTHER PTHR30011:SF14 21 287 4.8E-39 T 23-04-2016 DC74_RS35335 bb0f3a4f761414b9e2dd40a348d2a205 296 Pfam PF00296 Luciferase-like monooxygenase 21 242 4.5E-32 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS35335 bb0f3a4f761414b9e2dd40a348d2a205 296 TIGRFAM TIGR03621 F420_MSMEG_2516: probable F420-dependent oxidoreductase, MSMEG_2516 family 5 293 1.0E-106 T 23-04-2016 IPR019923 Luciferase-like, F420-dependent oxidoreductase, MSMEG2516, predicted DC74_RS35335 bb0f3a4f761414b9e2dd40a348d2a205 296 Gene3D G3DSA:3.20.20.30 4 279 4.9E-56 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS09065 b62f1f09467aaca447fe26979750f21b 140 PANTHER PTHR36115 50 138 2.7E-14 T 23-04-2016 DC74_RS09065 b62f1f09467aaca447fe26979750f21b 140 Pfam PF06271 RDD family 2 131 3.8E-20 T 23-04-2016 IPR010432 RDD DC74_RS09065 b62f1f09467aaca447fe26979750f21b 140 PANTHER PTHR36115:SF3 50 138 2.7E-14 T 23-04-2016 DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 Gene3D G3DSA:1.10.10.10 7 58 2.2E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 ProSitePatterns PS00519 AsnC-type HTH domain signature. 24 50 - T 23-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 Pfam PF01037 Lrp/AsnC ligand binding domain 81 138 2.3E-12 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 PANTHER PTHR30154 1 140 5.6E-54 T 23-04-2016 DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 SMART SM00344 7 112 4.3E-32 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 SUPERFAMILY SSF54909 67 141 1.64E-13 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 52 6.2E-17 T 23-04-2016 DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 Gene3D G3DSA:3.30.70.920 59 133 7.7E-17 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 1.9E-15 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 1.9E-15 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 1.9E-15 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 SUPERFAMILY SSF46785 7 65 3.25E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35245 e6f0a674b14324900dd86a592e4d2bc5 148 PANTHER PTHR30154:SF16 1 140 5.6E-54 T 23-04-2016 DC74_RS37455 546c02b5b290c24210e48dbae791d8bb 394 Pfam PF00296 Luciferase-like monooxygenase 8 315 2.0E-38 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS37455 546c02b5b290c24210e48dbae791d8bb 394 PANTHER PTHR30137 1 360 3.7E-129 T 23-04-2016 DC74_RS37455 546c02b5b290c24210e48dbae791d8bb 394 SUPERFAMILY SSF51679 7 351 3.27E-68 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS37455 546c02b5b290c24210e48dbae791d8bb 394 PANTHER PTHR30137:SF1 1 360 3.7E-129 T 23-04-2016 DC74_RS37455 546c02b5b290c24210e48dbae791d8bb 394 Gene3D G3DSA:3.20.20.30 8 350 7.3E-72 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS31065 53ac1a6b70d98572589f286e1109a290 456 Gene3D G3DSA:2.60.120.10 74 195 1.1E-15 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS31065 53ac1a6b70d98572589f286e1109a290 456 PANTHER PTHR24567:SF37 7 198 4.9E-94 T 23-04-2016 DC74_RS31065 53ac1a6b70d98572589f286e1109a290 456 PANTHER PTHR24567:SF37 264 452 4.9E-94 T 23-04-2016 DC74_RS31065 53ac1a6b70d98572589f286e1109a290 456 SMART SM00100 79 197 9.9E-6 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS31065 53ac1a6b70d98572589f286e1109a290 456 Pfam PF00027 Cyclic nucleotide-binding domain 98 185 5.6E-11 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS31065 53ac1a6b70d98572589f286e1109a290 456 PANTHER PTHR24567 7 198 4.9E-94 T 23-04-2016 DC74_RS31065 53ac1a6b70d98572589f286e1109a290 456 PANTHER PTHR24567 264 452 4.9E-94 T 23-04-2016 DC74_RS31065 53ac1a6b70d98572589f286e1109a290 456 SUPERFAMILY SSF51206 72 189 7.59E-18 T 23-04-2016 IPR018490 Cyclic nucleotide-binding-like DC74_RS38770 f1790e89d6f3ebbcfe7e83c42ac57972 952 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 887 901 8.1E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38770 f1790e89d6f3ebbcfe7e83c42ac57972 952 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 917 929 8.1E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38770 f1790e89d6f3ebbcfe7e83c42ac57972 952 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 901 917 8.1E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38770 f1790e89d6f3ebbcfe7e83c42ac57972 952 Gene3D G3DSA:1.10.10.10 881 941 1.9E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38770 f1790e89d6f3ebbcfe7e83c42ac57972 952 Gene3D G3DSA:1.25.40.10 579 773 3.5E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS38770 f1790e89d6f3ebbcfe7e83c42ac57972 952 Gene3D G3DSA:1.25.40.10 407 435 3.5E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS38770 f1790e89d6f3ebbcfe7e83c42ac57972 952 SMART SM00421 884 941 8.4E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38770 f1790e89d6f3ebbcfe7e83c42ac57972 952 Pfam PF00196 Bacterial regulatory proteins, luxR family 886 940 2.2E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS38770 f1790e89d6f3ebbcfe7e83c42ac57972 952 SUPERFAMILY SSF46894 874 941 4.08E-14 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS38770 f1790e89d6f3ebbcfe7e83c42ac57972 952 ProSitePatterns PS00622 LuxR-type HTH domain signature. 901 928 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS33915 739af5970033ccae0f8c606c4e7ecffc 290 Gene3D G3DSA:2.60.40.1120 32 107 2.6E-9 T 23-04-2016 IPR014766 Carboxypeptidase, regulatory domain DC74_RS33915 739af5970033ccae0f8c606c4e7ecffc 290 SUPERFAMILY SSF101874 118 289 3.79E-44 T 23-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like DC74_RS33915 739af5970033ccae0f8c606c4e7ecffc 290 Gene3D G3DSA:2.40.128.110 118 288 4.7E-49 T 23-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like DC74_RS33915 739af5970033ccae0f8c606c4e7ecffc 290 Pfam PF04264 YceI-like domain 120 286 5.6E-34 T 23-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like DC74_RS33915 739af5970033ccae0f8c606c4e7ecffc 290 SUPERFAMILY SSF49464 32 106 9.02E-9 T 23-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain DC74_RS33915 739af5970033ccae0f8c606c4e7ecffc 290 PANTHER PTHR34406 65 288 4.9E-45 T 23-04-2016 DC74_RS33915 739af5970033ccae0f8c606c4e7ecffc 290 Pfam PF13620 Carboxypeptidase regulatory-like domain 31 106 4.9E-12 T 23-04-2016 DC74_RS33915 739af5970033ccae0f8c606c4e7ecffc 290 SMART SM00867 119 287 2.1E-48 T 23-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like DC74_RS33915 739af5970033ccae0f8c606c4e7ecffc 290 PANTHER PTHR34406:SF1 65 288 4.9E-45 T 23-04-2016 DC74_RS22725 f935822e0dc69c69f9d44d4691b4e4b2 270 Pfam PF01261 Xylose isomerase-like TIM barrel 25 211 1.6E-16 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS22725 f935822e0dc69c69f9d44d4691b4e4b2 270 Gene3D G3DSA:3.20.20.150 4 261 8.3E-48 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS22725 f935822e0dc69c69f9d44d4691b4e4b2 270 SUPERFAMILY SSF51658 5 261 2.36E-46 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS22725 f935822e0dc69c69f9d44d4691b4e4b2 270 PANTHER PTHR12110 2 266 1.3E-72 T 23-04-2016 DC74_RS22725 f935822e0dc69c69f9d44d4691b4e4b2 270 PANTHER PTHR12110:SF17 2 266 1.3E-72 T 23-04-2016 DC74_RS11385 342474415fe338d73b608ff03c22cf62 420 Pfam PF04909 Amidohydrolase 53 376 2.6E-38 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS11385 342474415fe338d73b608ff03c22cf62 420 PANTHER PTHR21240 305 386 1.2E-31 T 23-04-2016 DC74_RS11385 342474415fe338d73b608ff03c22cf62 420 PANTHER PTHR21240 119 287 1.2E-31 T 23-04-2016 DC74_RS11385 342474415fe338d73b608ff03c22cf62 420 Gene3D G3DSA:3.20.20.140 19 383 1.1E-58 T 23-04-2016 DC74_RS11385 342474415fe338d73b608ff03c22cf62 420 SUPERFAMILY SSF51556 17 377 6.08E-63 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS34775 a0a45ef5769d2eab18a6c70bb5d56b41 218 PANTHER PTHR30055:SF51 11 208 4.0E-66 T 23-04-2016 DC74_RS34775 a0a45ef5769d2eab18a6c70bb5d56b41 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 69 1.3E-14 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34775 a0a45ef5769d2eab18a6c70bb5d56b41 218 Gene3D G3DSA:1.10.357.10 12 197 1.0E-33 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS34775 a0a45ef5769d2eab18a6c70bb5d56b41 218 SUPERFAMILY SSF48498 94 193 2.0E-5 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS34775 a0a45ef5769d2eab18a6c70bb5d56b41 218 SUPERFAMILY SSF46689 18 85 3.49E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS34775 a0a45ef5769d2eab18a6c70bb5d56b41 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 9.8E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34775 a0a45ef5769d2eab18a6c70bb5d56b41 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 9.8E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34775 a0a45ef5769d2eab18a6c70bb5d56b41 218 PANTHER PTHR30055 11 208 4.0E-66 T 23-04-2016 DC74_RS38390 302f99240fec09b63c4ba079664b7164 501 PANTHER PTHR38657:SF1 1 498 7.9E-212 T 23-04-2016 DC74_RS38390 302f99240fec09b63c4ba079664b7164 501 SUPERFAMILY SSF48173 220 480 1.31E-51 T 23-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain DC74_RS38390 302f99240fec09b63c4ba079664b7164 501 PANTHER PTHR38657 1 498 7.9E-212 T 23-04-2016 DC74_RS38390 302f99240fec09b63c4ba079664b7164 501 Gene3D G3DSA:1.25.40.80 220 305 2.1E-13 T 23-04-2016 DC74_RS38390 302f99240fec09b63c4ba079664b7164 501 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 6 202 1.4E-34 T 23-04-2016 IPR007357 Deoxyribodipyrimidine photolyase-related protein DC74_RS38390 302f99240fec09b63c4ba079664b7164 501 Gene3D G3DSA:1.10.579.10 306 399 1.4E-6 T 23-04-2016 DC74_RS02470 8ca720ed2277c7913bf554cfd7ccc755 264 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 78 232 6.0E-47 T 23-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DC74_RS02470 8ca720ed2277c7913bf554cfd7ccc755 264 Gene3D G3DSA:3.40.50.720 8 61 3.1E-11 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02470 8ca720ed2277c7913bf554cfd7ccc755 264 PANTHER PTHR10996 33 241 2.9E-66 T 23-04-2016 DC74_RS02470 8ca720ed2277c7913bf554cfd7ccc755 264 SUPERFAMILY SSF52283 5 77 2.0E-10 T 23-04-2016 DC74_RS02470 8ca720ed2277c7913bf554cfd7ccc755 264 Gene3D G3DSA:3.40.50.720 62 233 6.4E-53 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02470 8ca720ed2277c7913bf554cfd7ccc755 264 SUPERFAMILY SSF51735 55 233 3.09E-47 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02470 8ca720ed2277c7913bf554cfd7ccc755 264 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 243 3.9E-7 T 23-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 DC74_RS16900 07631e219c2bd187ffdfc9ece1393753 324 PANTHER PTHR11603 9 324 2.5E-148 T 23-04-2016 DC74_RS16900 07631e219c2bd187ffdfc9ece1393753 324 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 46 176 2.2E-63 T 23-04-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 DC74_RS16900 07631e219c2bd187ffdfc9ece1393753 324 SUPERFAMILY SSF52540 13 299 3.6E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16900 07631e219c2bd187ffdfc9ece1393753 324 PANTHER PTHR11603:SF148 9 324 2.5E-148 T 23-04-2016 DC74_RS16900 07631e219c2bd187ffdfc9ece1393753 324 Gene3D G3DSA:3.40.50.300 28 192 2.4E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16900 07631e219c2bd187ffdfc9ece1393753 324 Gene3D G3DSA:1.10.8.300 212 318 1.1E-38 T 23-04-2016 DC74_RS16900 07631e219c2bd187ffdfc9ece1393753 324 PIRSF PIRSF002849 2 324 4.5E-131 T 23-04-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted DC74_RS14765 b146ff0224b4ff6aab36a9644d21d0a1 280 SUPERFAMILY SSF46785 195 271 6.17E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14765 b146ff0224b4ff6aab36a9644d21d0a1 280 Gene3D G3DSA:1.10.10.10 204 267 2.7E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14765 b146ff0224b4ff6aab36a9644d21d0a1 280 SMART SM00418 197 272 0.0027 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS14765 b146ff0224b4ff6aab36a9644d21d0a1 280 Pfam PF12840 Helix-turn-helix domain 205 252 6.9E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08720 97963b6238172b8ee75b3abfd25bcd7a 382 Pfam PF13641 Glycosyltransferase like family 2 39 270 6.6E-22 T 23-04-2016 DC74_RS08720 97963b6238172b8ee75b3abfd25bcd7a 382 PANTHER PTHR10859 22 338 9.0E-101 T 23-04-2016 DC74_RS08720 97963b6238172b8ee75b3abfd25bcd7a 382 Gene3D G3DSA:3.90.550.10 39 248 3.7E-22 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS08720 97963b6238172b8ee75b3abfd25bcd7a 382 TIGRFAM TIGR03469 HpnB: hopene-associated glycosyltransferase HpnB 4 379 9.7E-149 T 23-04-2016 IPR017832 Glycosyl transferase, family 2, hopene-associated, HpnB DC74_RS08720 97963b6238172b8ee75b3abfd25bcd7a 382 PANTHER PTHR10859:SF75 22 338 9.0E-101 T 23-04-2016 DC74_RS08720 97963b6238172b8ee75b3abfd25bcd7a 382 SUPERFAMILY SSF53448 31 268 1.94E-36 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 PANTHER PTHR23151 4 124 8.3E-140 T 23-04-2016 DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 PANTHER PTHR23151 186 477 8.3E-140 T 23-04-2016 DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 SUPERFAMILY SSF51230 4 94 1.16E-23 T 23-04-2016 IPR011053 Single hybrid motif DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 Gene3D G3DSA:2.40.50.100 5 89 5.0E-23 T 23-04-2016 DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 Gene3D G3DSA:4.10.320.10 189 229 7.4E-15 T 23-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 SUPERFAMILY SSF47005 186 227 1.83E-10 T 23-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 Pfam PF00364 Biotin-requiring enzyme 6 77 1.8E-16 T 23-04-2016 IPR000089 Biotin/lipoyl attachment DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 252 477 9.1E-70 T 23-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 Gene3D G3DSA:3.30.559.10 250 477 4.0E-72 T 23-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 SUPERFAMILY SSF52777 251 478 2.58E-68 T 23-04-2016 DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 Pfam PF02817 e3 binding domain 191 224 6.0E-12 T 23-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 PANTHER PTHR23151:SF68 4 124 8.3E-140 T 23-04-2016 DC74_RS20415 4ec45119a963a005558ed75c6eab71b2 480 PANTHER PTHR23151:SF68 186 477 8.3E-140 T 23-04-2016 DC74_RS36405 471ad254f67a56e0d978f899adf38c38 378 PANTHER PTHR21266 3 374 6.2E-101 T 23-04-2016 DC74_RS36405 471ad254f67a56e0d978f899adf38c38 378 Pfam PF00355 Rieske [2Fe-2S] domain 24 107 7.6E-17 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS36405 471ad254f67a56e0d978f899adf38c38 378 SUPERFAMILY SSF50022 13 132 1.28E-28 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS36405 471ad254f67a56e0d978f899adf38c38 378 Gene3D G3DSA:2.102.10.10 22 138 1.8E-28 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS36405 471ad254f67a56e0d978f899adf38c38 378 PANTHER PTHR21266:SF31 3 374 6.2E-101 T 23-04-2016 DC74_RS36405 471ad254f67a56e0d978f899adf38c38 378 SUPERFAMILY SSF55961 131 344 1.51E-30 T 23-04-2016 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 Pfam PF08264 Anticodon-binding domain of tRNA 687 832 2.1E-29 T 23-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 SUPERFAMILY SSF52374 394 648 6.19E-123 T 23-04-2016 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 SUPERFAMILY SSF52374 10 203 6.19E-123 T 23-04-2016 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 Gene3D G3DSA:3.40.50.620 10 199 1.6E-133 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 Gene3D G3DSA:3.40.50.620 397 636 1.6E-133 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 SUPERFAMILY SSF50677 206 394 2.62E-43 T 23-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 23 628 1.1E-165 T 23-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 8 1041 13.68 T 23-04-2016 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 SUPERFAMILY SSF47323 655 892 9.91E-49 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 Gene3D G3DSA:3.90.740.10 208 380 4.4E-49 T 23-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 PANTHER PTHR11946:SF87 270 935 0.0 T 23-04-2016 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 PANTHER PTHR11946:SF87 1 250 0.0 T 23-04-2016 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 10 838 2.2E-267 T 23-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 Gene3D G3DSA:1.10.730.10 646 823 4.1E-46 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 519 532 1.6E-26 T 23-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 392 407 1.6E-26 T 23-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 46 57 1.6E-26 T 23-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 229 252 1.6E-26 T 23-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 559 568 1.6E-26 T 23-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 PANTHER PTHR11946 270 935 0.0 T 23-04-2016 DC74_RS12500 e9b21c645229b9b7fe5ead9219c26987 1047 PANTHER PTHR11946 1 250 0.0 T 23-04-2016 DC74_RS06295 84d816a544456f3a84c7e17bf2234525 229 Gene3D G3DSA:2.40.33.20 3 218 2.6E-70 T 23-04-2016 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like DC74_RS06295 84d816a544456f3a84c7e17bf2234525 229 PANTHER PTHR30212 1 216 5.5E-44 T 23-04-2016 DC74_RS06295 84d816a544456f3a84c7e17bf2234525 229 PANTHER PTHR30212:SF2 1 216 5.5E-44 T 23-04-2016 DC74_RS06295 84d816a544456f3a84c7e17bf2234525 229 SUPERFAMILY SSF50800 4 204 4.87E-54 T 23-04-2016 IPR011037 Pyruvate kinase-like, insert domain DC74_RS06295 84d816a544456f3a84c7e17bf2234525 229 Pfam PF03473 MOSC domain 61 173 8.2E-24 T 23-04-2016 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 DC74_RS25720 adce60e636a0e6a1d061a10fbe3e1f38 145 SUPERFAMILY SSF88697 15 119 5.47E-5 T 23-04-2016 IPR015947 PUA-like domain DC74_RS25720 adce60e636a0e6a1d061a10fbe3e1f38 145 Gene3D G3DSA:3.10.590.10 15 121 5.2E-5 T 23-04-2016 IPR002740 EVE domain DC74_RS07730 892992224cdefc7174d7238d106a4227 276 Gene3D G3DSA:3.60.21.10 2 222 2.5E-30 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS07730 892992224cdefc7174d7238d106a4227 276 PANTHER PTHR12905:SF7 1 17 2.0E-22 T 23-04-2016 DC74_RS07730 892992224cdefc7174d7238d106a4227 276 SUPERFAMILY SSF56300 1 224 2.39E-45 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS07730 892992224cdefc7174d7238d106a4227 276 Pfam PF00149 Calcineurin-like phosphoesterase 2 200 3.7E-14 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS07730 892992224cdefc7174d7238d106a4227 276 PANTHER PTHR12905 1 17 2.0E-22 T 23-04-2016 DC74_RS07730 892992224cdefc7174d7238d106a4227 276 PANTHER PTHR12905 34 219 2.0E-22 T 23-04-2016 DC74_RS07730 892992224cdefc7174d7238d106a4227 276 PANTHER PTHR12905:SF7 34 219 2.0E-22 T 23-04-2016 DC74_RS13665 c7eddce89cd9778995f2e679310090b5 359 SMART SM00849 26 269 6.9E-21 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS13665 c7eddce89cd9778995f2e679310090b5 359 PANTHER PTHR23131:SF4 212 346 1.7E-32 T 23-04-2016 DC74_RS13665 c7eddce89cd9778995f2e679310090b5 359 PANTHER PTHR23131:SF4 159 195 1.7E-32 T 23-04-2016 DC74_RS13665 c7eddce89cd9778995f2e679310090b5 359 PANTHER PTHR23131:SF4 15 134 1.7E-32 T 23-04-2016 DC74_RS13665 c7eddce89cd9778995f2e679310090b5 359 Pfam PF00753 Metallo-beta-lactamase superfamily 25 269 1.5E-13 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS13665 c7eddce89cd9778995f2e679310090b5 359 SUPERFAMILY SSF56281 10 350 5.9E-53 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS13665 c7eddce89cd9778995f2e679310090b5 359 Gene3D G3DSA:3.60.15.10 9 106 7.5E-46 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS13665 c7eddce89cd9778995f2e679310090b5 359 Gene3D G3DSA:3.60.15.10 138 312 7.5E-46 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS13665 c7eddce89cd9778995f2e679310090b5 359 PANTHER PTHR23131 212 346 1.7E-32 T 23-04-2016 DC74_RS13665 c7eddce89cd9778995f2e679310090b5 359 PANTHER PTHR23131 159 195 1.7E-32 T 23-04-2016 DC74_RS13665 c7eddce89cd9778995f2e679310090b5 359 PANTHER PTHR23131 15 134 1.7E-32 T 23-04-2016 DC74_RS21825 1af28e8c5c2d4ff6f28cb516280ac54d 305 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 129 143 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DC74_RS21825 1af28e8c5c2d4ff6f28cb516280ac54d 305 Pfam PF08443 RimK-like ATP-grasp domain 94 257 6.5E-5 T 23-04-2016 IPR013651 ATP-grasp fold, RimK-type DC74_RS21825 1af28e8c5c2d4ff6f28cb516280ac54d 305 Gene3D G3DSA:3.40.50.20 4 97 2.7E-6 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS21825 1af28e8c5c2d4ff6f28cb516280ac54d 305 Gene3D G3DSA:3.30.470.20 168 258 5.8E-5 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS21825 1af28e8c5c2d4ff6f28cb516280ac54d 305 PANTHER PTHR21621 18 261 2.3E-19 T 23-04-2016 DC74_RS21825 1af28e8c5c2d4ff6f28cb516280ac54d 305 Gene3D G3DSA:3.30.1490.20 98 154 3.8E-12 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS21825 1af28e8c5c2d4ff6f28cb516280ac54d 305 SUPERFAMILY SSF56059 95 258 1.63E-22 T 23-04-2016 DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 SUPERFAMILY SSF56024 912 1061 2.33E-17 T 23-04-2016 DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 Pfam PF13086 AAA domain 159 629 1.0E-27 T 23-04-2016 DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 PANTHER PTHR10887 499 642 5.3E-53 T 23-04-2016 DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 PANTHER PTHR10887 155 233 5.3E-53 T 23-04-2016 DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 PANTHER PTHR10887 663 720 5.3E-53 T 23-04-2016 DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 PANTHER PTHR10887 832 848 5.3E-53 T 23-04-2016 DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 PANTHER PTHR10887 740 808 5.3E-53 T 23-04-2016 DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 Gene3D G3DSA:3.40.50.300 151 236 9.1E-29 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 Gene3D G3DSA:3.40.50.300 588 695 9.1E-29 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 Gene3D G3DSA:3.40.50.300 302 303 9.1E-29 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 Gene3D G3DSA:3.30.870.10 915 1059 2.2E-15 T 23-04-2016 DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 Pfam PF13091 PLD-like domain 929 1056 3.0E-9 T 23-04-2016 IPR025202 Phospholipase D-like domain DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 SMART SM00382 164 712 2.3E-5 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 Pfam PF13087 AAA domain 745 849 5.9E-13 T 23-04-2016 DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 SUPERFAMILY SSF52540 539 852 9.91E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 SUPERFAMILY SSF52540 155 217 9.91E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25290 250e5fbe065038609b9ca236cf1460b6 1148 Gene3D G3DSA:3.40.50.300 742 850 1.5E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20550 edb46aa7c3137b757f8dfed50b0766e3 175 Gene3D G3DSA:2.60.200.20 81 174 2.1E-26 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS20550 edb46aa7c3137b757f8dfed50b0766e3 175 PANTHER PTHR21712:SF36 1 158 6.6E-54 T 23-04-2016 DC74_RS20550 edb46aa7c3137b757f8dfed50b0766e3 175 SMART SM00240 101 152 7.6E-13 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS20550 edb46aa7c3137b757f8dfed50b0766e3 175 SUPERFAMILY SSF49879 52 174 1.61E-27 T 23-04-2016 IPR008984 SMAD/FHA domain GO:0005515 DC74_RS20550 edb46aa7c3137b757f8dfed50b0766e3 175 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 87 174 1.8E-15 T 23-04-2016 IPR032030 YscD, cytoplasmic domain DC74_RS20550 edb46aa7c3137b757f8dfed50b0766e3 175 PANTHER PTHR21712 1 158 6.6E-54 T 23-04-2016 DC74_RS19220 0771981b00890d3554f710be15e1e839 387 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 6 371 49.37 T 23-04-2016 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 DC74_RS19220 0771981b00890d3554f710be15e1e839 387 Gene3D G3DSA:3.20.20.70 17 360 3.8E-55 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS19220 0771981b00890d3554f710be15e1e839 387 PIRSF PIRSF004762 1 381 1.1E-100 T 23-04-2016 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 DC74_RS19220 0771981b00890d3554f710be15e1e839 387 Pfam PF04055 Radical SAM superfamily 61 229 8.6E-11 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS19220 0771981b00890d3554f710be15e1e839 387 PANTHER PTHR22976:SF4 7 385 4.4E-173 T 23-04-2016 DC74_RS19220 0771981b00890d3554f710be15e1e839 387 PANTHER PTHR22976 7 385 4.4E-173 T 23-04-2016 DC74_RS19220 0771981b00890d3554f710be15e1e839 387 SUPERFAMILY SSF102114 16 361 8.89E-44 T 23-04-2016 DC74_RS19220 0771981b00890d3554f710be15e1e839 387 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 52 368 4.2E-91 T 23-04-2016 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 DC74_RS19220 0771981b00890d3554f710be15e1e839 387 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 10 368 9.7E-163 T 23-04-2016 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 DC74_RS18755 96f3820448f5ccc8ef5d2f8aff3a8a6d 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.1E-63 T 23-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 DC74_RS18755 96f3820448f5ccc8ef5d2f8aff3a8a6d 156 Gene3D G3DSA:1.10.455.10 8 156 4.8E-59 T 23-04-2016 IPR023798 Ribosomal protein S7 domain DC74_RS18755 96f3820448f5ccc8ef5d2f8aff3a8a6d 156 PANTHER PTHR11205 1 156 6.3E-82 T 23-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 DC74_RS18755 96f3820448f5ccc8ef5d2f8aff3a8a6d 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.3E-58 T 23-04-2016 IPR023798 Ribosomal protein S7 domain DC74_RS18755 96f3820448f5ccc8ef5d2f8aff3a8a6d 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 23-04-2016 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 DC74_RS18755 96f3820448f5ccc8ef5d2f8aff3a8a6d 156 SUPERFAMILY SSF47973 1 149 5.49E-56 T 23-04-2016 IPR023798 Ribosomal protein S7 domain DC74_RS18755 96f3820448f5ccc8ef5d2f8aff3a8a6d 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.329 T 23-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 DC74_RS18755 96f3820448f5ccc8ef5d2f8aff3a8a6d 156 PIRSF PIRSF002122 7 156 7.0E-54 T 23-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 DC74_RS19015 ac1328e43c9f12a3c4c6bd8a2e609847 552 Pfam PF00361 Proton-conducting membrane transporter 142 452 2.7E-64 T 23-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 DC74_RS19015 ac1328e43c9f12a3c4c6bd8a2e609847 552 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 410 436 3.1E-28 T 23-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 DC74_RS19015 ac1328e43c9f12a3c4c6bd8a2e609847 552 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 270 294 3.1E-28 T 23-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 DC74_RS19015 ac1328e43c9f12a3c4c6bd8a2e609847 552 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 148 167 3.1E-28 T 23-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 DC74_RS19015 ac1328e43c9f12a3c4c6bd8a2e609847 552 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 189 213 3.1E-28 T 23-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 DC74_RS19015 ac1328e43c9f12a3c4c6bd8a2e609847 552 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 358 377 3.1E-28 T 23-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 DC74_RS19015 ac1328e43c9f12a3c4c6bd8a2e609847 552 PANTHER PTHR22773 1 522 1.6E-176 T 23-04-2016 DC74_RS19015 ac1328e43c9f12a3c4c6bd8a2e609847 552 PANTHER PTHR22773:SF40 1 522 1.6E-176 T 23-04-2016 DC74_RS19015 ac1328e43c9f12a3c4c6bd8a2e609847 552 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 518 3.6E-175 T 23-04-2016 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 DC74_RS10195 baa55bace7b2443892e7af81823dcbef 388 PANTHER PTHR31686 24 388 3.7E-168 T 23-04-2016 DC74_RS10195 baa55bace7b2443892e7af81823dcbef 388 PANTHER PTHR31686:SF2 24 388 3.7E-168 T 23-04-2016 DC74_RS10195 baa55bace7b2443892e7af81823dcbef 388 Pfam PF03595 Voltage-dependent anion channel 28 362 6.7E-65 T 23-04-2016 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 DC74_RS31550 c7d709dff70386481b81d9d8aebb675a 535 SUPERFAMILY SSF49785 409 534 1.59E-15 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS31550 c7d709dff70386481b81d9d8aebb675a 535 SUPERFAMILY SSF53474 54 355 1.66E-50 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31550 c7d709dff70386481b81d9d8aebb675a 535 Gene3D G3DSA:2.60.120.260 406 534 7.8E-15 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS31550 c7d709dff70386481b81d9d8aebb675a 535 SMART SM00939 319 529 4.3E-21 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 DC74_RS31550 c7d709dff70386481b81d9d8aebb675a 535 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 63 355 8.7E-22 T 23-04-2016 IPR005674 CocE/Serine esterase GO:0016787 DC74_RS31550 c7d709dff70386481b81d9d8aebb675a 535 PANTHER PTHR11731 54 191 5.3E-17 T 23-04-2016 DC74_RS31550 c7d709dff70386481b81d9d8aebb675a 535 Gene3D G3DSA:3.40.50.1820 32 195 1.5E-51 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31550 c7d709dff70386481b81d9d8aebb675a 535 Gene3D G3DSA:3.40.50.1820 247 351 1.5E-51 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31550 c7d709dff70386481b81d9d8aebb675a 535 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 412 520 1.3E-13 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 DC74_RS31550 c7d709dff70386481b81d9d8aebb675a 535 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 63 300 8.6E-35 T 23-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 DC74_RS17710 eeee5179e9caff743a8da58f415bb8a3 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 67 82 5.9E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS17710 eeee5179e9caff743a8da58f415bb8a3 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 5.9E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS17710 eeee5179e9caff743a8da58f415bb8a3 321 PRINTS PR00111 Alpha/beta hydrolase fold signature 242 256 5.9E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS17710 eeee5179e9caff743a8da58f415bb8a3 321 Pfam PF12146 Serine aminopeptidase, S33 42 284 1.1E-20 T 23-04-2016 IPR022742 Serine aminopeptidase, S33 DC74_RS17710 eeee5179e9caff743a8da58f415bb8a3 321 PANTHER PTHR10992:SF771 215 299 5.2E-41 T 23-04-2016 DC74_RS17710 eeee5179e9caff743a8da58f415bb8a3 321 PANTHER PTHR10992:SF771 15 188 5.2E-41 T 23-04-2016 DC74_RS17710 eeee5179e9caff743a8da58f415bb8a3 321 Gene3D G3DSA:3.40.50.1820 23 299 3.7E-52 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS17710 eeee5179e9caff743a8da58f415bb8a3 321 SUPERFAMILY SSF53474 15 296 6.51E-51 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS17710 eeee5179e9caff743a8da58f415bb8a3 321 PANTHER PTHR10992 215 299 5.2E-41 T 23-04-2016 DC74_RS17710 eeee5179e9caff743a8da58f415bb8a3 321 PANTHER PTHR10992 15 188 5.2E-41 T 23-04-2016 DC74_RS11020 aec7ccb89a60c37343c4860d35b2f752 241 Pfam PF10127 Predicted nucleotidyltransferase 23 230 2.1E-35 T 23-04-2016 IPR018775 Nucleotidyltransferase, predicted DC74_RS11020 aec7ccb89a60c37343c4860d35b2f752 241 PANTHER PTHR34817 25 241 1.5E-69 T 23-04-2016 DC74_RS11020 aec7ccb89a60c37343c4860d35b2f752 241 PANTHER PTHR34817:SF2 25 241 1.5E-69 T 23-04-2016 DC74_RS34620 b4577a70206ec1f3996ce210ea6d7223 286 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 3 235 9.8E-53 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS34620 b4577a70206ec1f3996ce210ea6d7223 286 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 94 112 4.7E-36 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS34620 b4577a70206ec1f3996ce210ea6d7223 286 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 162 190 4.7E-36 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS34620 b4577a70206ec1f3996ce210ea6d7223 286 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 2 29 4.7E-36 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS34620 b4577a70206ec1f3996ce210ea6d7223 286 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 112 138 4.7E-36 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS34620 b4577a70206ec1f3996ce210ea6d7223 286 PANTHER PTHR30371:SF0 1 268 2.0E-86 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS34620 b4577a70206ec1f3996ce210ea6d7223 286 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 249 16.341 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS34620 b4577a70206ec1f3996ce210ea6d7223 286 Pfam PF00902 Sec-independent protein translocase protein (TatC) 5 230 8.6E-59 T 23-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DC74_RS34620 b4577a70206ec1f3996ce210ea6d7223 286 PANTHER PTHR30371 1 268 2.0E-86 T 23-04-2016 DC74_RS17150 931bec9b38d3305cf61e106a11dfdcc4 133 Pfam PF09394 Chagasin family peptidase inhibitor I42 35 118 1.0E-6 T 23-04-2016 IPR018990 Proteinase inhibitor I42, chagasin DC74_RS17150 931bec9b38d3305cf61e106a11dfdcc4 133 SUPERFAMILY SSF141066 27 113 6.67E-5 T 23-04-2016 IPR018990 Proteinase inhibitor I42, chagasin DC74_RS07675 84e35407a4ab756ac7ab0885a647894c 238 SMART SM00020 39 232 2.4E-18 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS07675 84e35407a4ab756ac7ab0885a647894c 238 Gene3D G3DSA:2.40.10.10 40 71 2.3E-10 T 23-04-2016 DC74_RS07675 84e35407a4ab756ac7ab0885a647894c 238 PANTHER PTHR24260:SF50 12 236 2.1E-101 T 23-04-2016 DC74_RS07675 84e35407a4ab756ac7ab0885a647894c 238 Gene3D G3DSA:2.40.10.10 72 235 1.9E-25 T 23-04-2016 DC74_RS07675 84e35407a4ab756ac7ab0885a647894c 238 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 190 202 8.5E-9 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS07675 84e35407a4ab756ac7ab0885a647894c 238 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 64 79 8.5E-9 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS07675 84e35407a4ab756ac7ab0885a647894c 238 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 108 122 8.5E-9 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS07675 84e35407a4ab756ac7ab0885a647894c 238 PANTHER PTHR24260 12 236 2.1E-101 T 23-04-2016 DC74_RS07675 84e35407a4ab756ac7ab0885a647894c 238 SUPERFAMILY SSF50494 18 236 2.0E-36 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS07675 84e35407a4ab756ac7ab0885a647894c 238 Pfam PF00089 Trypsin 45 232 1.9E-27 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS33360 7182a647f9cd14eac56344507118ee5a 417 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 118 1.5E-27 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS33360 7182a647f9cd14eac56344507118ee5a 417 Gene3D G3DSA:1.20.140.10 217 382 3.8E-38 T 23-04-2016 DC74_RS33360 7182a647f9cd14eac56344507118ee5a 417 Gene3D G3DSA:2.40.110.10 123 216 1.8E-31 T 23-04-2016 DC74_RS33360 7182a647f9cd14eac56344507118ee5a 417 Gene3D G3DSA:1.10.540.10 6 118 3.0E-32 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS33360 7182a647f9cd14eac56344507118ee5a 417 SUPERFAMILY SSF47203 237 382 2.09E-31 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS33360 7182a647f9cd14eac56344507118ee5a 417 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 215 6.4E-22 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS33360 7182a647f9cd14eac56344507118ee5a 417 PIRSF PIRSF016578 3 379 3.7E-13 T 23-04-2016 DC74_RS33360 7182a647f9cd14eac56344507118ee5a 417 PANTHER PTHR10909 7 370 2.7E-96 T 23-04-2016 DC74_RS33360 7182a647f9cd14eac56344507118ee5a 417 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 374 2.9E-26 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS33360 7182a647f9cd14eac56344507118ee5a 417 SUPERFAMILY SSF56645 4 234 1.7E-68 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS39610 0058226f066e67dbf5433b88084901ee 198 PANTHER PTHR30055:SF19 9 172 1.7E-49 T 23-04-2016 DC74_RS39610 0058226f066e67dbf5433b88084901ee 198 Gene3D G3DSA:1.10.357.10 15 195 4.6E-41 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS39610 0058226f066e67dbf5433b88084901ee 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 3.5E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39610 0058226f066e67dbf5433b88084901ee 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 3.5E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39610 0058226f066e67dbf5433b88084901ee 198 SUPERFAMILY SSF48498 92 195 7.69E-10 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS39610 0058226f066e67dbf5433b88084901ee 198 PANTHER PTHR30055 9 172 1.7E-49 T 23-04-2016 DC74_RS39610 0058226f066e67dbf5433b88084901ee 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 1.1E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39610 0058226f066e67dbf5433b88084901ee 198 SUPERFAMILY SSF46689 12 95 4.04E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS33995 1eecb803a8ce39baefd87afe8a70ba0e 837 Pfam PF00270 DEAD/DEAH box helicase 33 178 7.5E-10 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS33995 1eecb803a8ce39baefd87afe8a70ba0e 837 SMART SM00490 277 363 1.5E-12 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS33995 1eecb803a8ce39baefd87afe8a70ba0e 837 SMART SM00487 27 212 9.6E-17 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS33995 1eecb803a8ce39baefd87afe8a70ba0e 837 Gene3D G3DSA:3.40.50.300 214 377 4.1E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33995 1eecb803a8ce39baefd87afe8a70ba0e 837 Gene3D G3DSA:3.40.50.300 17 193 9.0E-30 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33995 1eecb803a8ce39baefd87afe8a70ba0e 837 PANTHER PTHR12131 317 363 7.1E-12 T 23-04-2016 DC74_RS33995 1eecb803a8ce39baefd87afe8a70ba0e 837 SUPERFAMILY SSF52540 44 250 8.77E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33995 1eecb803a8ce39baefd87afe8a70ba0e 837 SUPERFAMILY SSF52540 283 375 8.77E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33995 1eecb803a8ce39baefd87afe8a70ba0e 837 Pfam PF12029 Domain of unknown function (DUF3516) 374 834 2.1E-218 T 23-04-2016 IPR021904 Protein of unknown function DUF3516 DC74_RS33995 1eecb803a8ce39baefd87afe8a70ba0e 837 Pfam PF00271 Helicase conserved C-terminal domain 244 363 4.1E-6 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS33995 1eecb803a8ce39baefd87afe8a70ba0e 837 PANTHER PTHR12131:SF4 317 363 7.1E-12 T 23-04-2016 DC74_RS40130 5504ce0d45f58c34f97f5b0b2e193c5c 75 Pfam PF00582 Universal stress protein family 12 73 3.1E-6 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS40130 5504ce0d45f58c34f97f5b0b2e193c5c 75 SUPERFAMILY SSF52402 4 74 2.43E-10 T 23-04-2016 DC74_RS40130 5504ce0d45f58c34f97f5b0b2e193c5c 75 Gene3D G3DSA:3.40.50.620 2 73 2.3E-10 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS32510 a12b604dcd161359ea851ad8c50fc916 131 SUPERFAMILY SSF55729 12 124 2.53E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS32510 a12b604dcd161359ea851ad8c50fc916 131 Pfam PF00583 Acetyltransferase (GNAT) family 47 121 1.9E-12 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS32510 a12b604dcd161359ea851ad8c50fc916 131 Gene3D G3DSA:3.40.630.30 14 123 1.8E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31655 c2ee35819861781c2688a427e48e3cf5 332 PANTHER PTHR30011 16 332 4.0E-98 T 23-04-2016 DC74_RS31655 c2ee35819861781c2688a427e48e3cf5 332 Pfam PF00296 Luciferase-like monooxygenase 11 306 8.8E-54 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS31655 c2ee35819861781c2688a427e48e3cf5 332 PANTHER PTHR30011:SF27 16 332 4.0E-98 T 23-04-2016 DC74_RS31655 c2ee35819861781c2688a427e48e3cf5 332 TIGRFAM TIGR03842 F420_CPS_4043: F420-dependent oxidoreductase, CPS_4043 family 2 331 2.0E-175 T 23-04-2016 IPR022315 F420-dependent oxidoreductase-predicted, CPS4043 DC74_RS31655 c2ee35819861781c2688a427e48e3cf5 332 Gene3D G3DSA:3.20.20.30 2 332 1.4E-70 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS31655 c2ee35819861781c2688a427e48e3cf5 332 SUPERFAMILY SSF51679 2 329 8.24E-61 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS29875 035abfa25f2f7e9f8b8d2ffc2fe38a04 165 Gene3D G3DSA:3.40.50.620 73 151 5.6E-11 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS29875 035abfa25f2f7e9f8b8d2ffc2fe38a04 165 SUPERFAMILY SSF52402 9 151 1.47E-20 T 23-04-2016 DC74_RS11070 3de8eb5d8b642ecee08fe5cdec69c0c6 562 SUPERFAMILY SSF52317 300 553 9.02E-69 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS11070 3de8eb5d8b642ecee08fe5cdec69c0c6 562 Pfam PF00117 Glutamine amidotransferase class-I 313 547 6.4E-47 T 23-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 DC74_RS11070 3de8eb5d8b642ecee08fe5cdec69c0c6 562 Gene3D G3DSA:3.40.50.880 299 553 4.0E-85 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS11070 3de8eb5d8b642ecee08fe5cdec69c0c6 562 Pfam PF06418 CTP synthase N-terminus 15 278 2.4E-121 T 23-04-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 DC74_RS11070 3de8eb5d8b642ecee08fe5cdec69c0c6 562 PANTHER PTHR11550 7 561 0.0 T 23-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 DC74_RS11070 3de8eb5d8b642ecee08fe5cdec69c0c6 562 Hamap MF_01227 CTP synthase [pyrG]. 14 552 50.228 T 23-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 DC74_RS11070 3de8eb5d8b642ecee08fe5cdec69c0c6 562 Gene3D G3DSA:3.40.50.300 7 296 2.3E-130 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11070 3de8eb5d8b642ecee08fe5cdec69c0c6 562 TIGRFAM TIGR00337 PyrG: CTP synthase 13 547 1.1E-227 T 23-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 DC74_RS11070 3de8eb5d8b642ecee08fe5cdec69c0c6 562 SUPERFAMILY SSF52540 14 278 4.2E-117 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05075 93316b7a228da2599cc8a1411fcaa991 365 PANTHER PTHR30472 14 365 4.8E-120 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS05075 93316b7a228da2599cc8a1411fcaa991 365 SUPERFAMILY SSF81345 32 359 6.54E-82 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS05075 93316b7a228da2599cc8a1411fcaa991 365 PANTHER PTHR30472:SF32 14 365 4.8E-120 T 23-04-2016 DC74_RS05075 93316b7a228da2599cc8a1411fcaa991 365 Pfam PF01032 FecCD transport family 40 357 1.9E-94 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS05075 93316b7a228da2599cc8a1411fcaa991 365 Gene3D G3DSA:1.10.3470.10 33 360 3.9E-106 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS02335 d4118dee6979b7f7a732d27e41afb798 219 Gene3D G3DSA:3.40.810.20 4 211 6.9E-90 T 23-04-2016 DC74_RS02335 d4118dee6979b7f7a732d27e41afb798 219 SMART SM00882 6 202 3.7E-73 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 DC74_RS02335 d4118dee6979b7f7a732d27e41afb798 219 SUPERFAMILY SSF100950 3 212 1.26E-70 T 23-04-2016 DC74_RS02335 d4118dee6979b7f7a732d27e41afb798 219 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 207 8.3E-98 T 23-04-2016 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 DC74_RS02335 d4118dee6979b7f7a732d27e41afb798 219 PANTHER PTHR13707 3 210 3.6E-122 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 DC74_RS02335 d4118dee6979b7f7a732d27e41afb798 219 Pfam PF01144 Coenzyme A transferase 7 201 8.5E-43 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 DC74_RS20795 47eec9e0e81648668e7ab779d050369b 759 SUPERFAMILY SSF56601 269 660 7.19E-79 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS20795 47eec9e0e81648668e7ab779d050369b 759 SUPERFAMILY SSF56601 215 237 7.19E-79 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS20795 47eec9e0e81648668e7ab779d050369b 759 Gene3D G3DSA:3.40.710.10 236 679 3.7E-95 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS20795 47eec9e0e81648668e7ab779d050369b 759 Pfam PF00905 Penicillin binding protein transpeptidase domain 342 593 2.9E-24 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS20795 47eec9e0e81648668e7ab779d050369b 759 SUPERFAMILY SSF53955 41 254 1.29E-62 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS20795 47eec9e0e81648668e7ab779d050369b 759 PANTHER PTHR32282:SF8 1 735 3.8E-235 T 23-04-2016 DC74_RS20795 47eec9e0e81648668e7ab779d050369b 759 Pfam PF00912 Transglycosylase 54 233 1.1E-54 T 23-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 DC74_RS20795 47eec9e0e81648668e7ab779d050369b 759 PANTHER PTHR32282 1 735 3.8E-235 T 23-04-2016 DC74_RS20795 47eec9e0e81648668e7ab779d050369b 759 Gene3D G3DSA:1.10.3810.10 50 235 5.8E-63 T 23-04-2016 DC74_RS05695 7fe54990d616945f448093e5cb7508e0 188 Gene3D G3DSA:3.40.50.1950 12 160 1.5E-20 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS05695 7fe54990d616945f448093e5cb7508e0 188 SUPERFAMILY SSF52507 15 154 3.01E-24 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS05695 7fe54990d616945f448093e5cb7508e0 188 PANTHER PTHR14359 41 153 7.5E-12 T 23-04-2016 DC74_RS05695 7fe54990d616945f448093e5cb7508e0 188 Pfam PF02441 Flavoprotein 18 137 3.0E-8 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS00365 86544ce75087f7f09b04f702bd14ff81 265 Gene3D G3DSA:3.40.50.720 17 202 2.6E-25 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00365 86544ce75087f7f09b04f702bd14ff81 265 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 138 1.9E-12 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS00365 86544ce75087f7f09b04f702bd14ff81 265 PANTHER PTHR10366 17 249 5.4E-30 T 23-04-2016 DC74_RS00365 86544ce75087f7f09b04f702bd14ff81 265 PANTHER PTHR10366:SF448 17 249 5.4E-30 T 23-04-2016 DC74_RS00365 86544ce75087f7f09b04f702bd14ff81 265 SUPERFAMILY SSF51735 2 261 3.31E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS24330 d87c8556f15f3696de5ae64b25532129 630 PANTHER PTHR24362:SF160 1 285 1.3E-90 T 23-04-2016 DC74_RS24330 d87c8556f15f3696de5ae64b25532129 630 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 144 156 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS24330 d87c8556f15f3696de5ae64b25532129 630 SMART SM00220 17 275 2.0E-64 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS24330 d87c8556f15f3696de5ae64b25532129 630 SUPERFAMILY SSF56112 13 273 1.58E-70 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS24330 d87c8556f15f3696de5ae64b25532129 630 PANTHER PTHR24362 1 285 1.3E-90 T 23-04-2016 DC74_RS24330 d87c8556f15f3696de5ae64b25532129 630 Gene3D G3DSA:3.30.200.20 7 86 1.9E-26 T 23-04-2016 DC74_RS24330 d87c8556f15f3696de5ae64b25532129 630 Pfam PF00069 Protein kinase domain 17 270 3.7E-48 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS24330 d87c8556f15f3696de5ae64b25532129 630 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 46 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS24330 d87c8556f15f3696de5ae64b25532129 630 Gene3D G3DSA:1.10.510.10 87 272 2.4E-48 T 23-04-2016 DC74_RS39615 47a442b03b2a0fe429a41162e0a2c41c 231 PANTHER PTHR38589 6 231 1.3E-49 T 23-04-2016 DC74_RS39615 47a442b03b2a0fe429a41162e0a2c41c 231 PANTHER PTHR38589:SF1 6 231 1.3E-49 T 23-04-2016 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 48 524 41.28 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 2.5E-54 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 2.5E-54 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 342 363 2.5E-54 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 152 171 2.5E-54 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 265 283 2.5E-54 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 2.5E-54 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 PANTHER PTHR11469 1 548 2.1E-300 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 23-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 SUPERFAMILY SSF53697 9 548 2.78E-206 T 23-04-2016 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 Gene3D G3DSA:3.40.50.10490 149 187 2.5E-153 T 23-04-2016 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 Gene3D G3DSA:3.40.50.10490 267 501 2.5E-153 T 23-04-2016 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 Gene3D G3DSA:3.40.50.10490 9 104 2.5E-153 T 23-04-2016 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 Gene3D G3DSA:1.10.1390.10 502 548 2.2E-21 T 23-04-2016 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS11800 60485a9316eeb80f09edb0e1eb6d41c3 550 Pfam PF00342 Phosphoglucose isomerase 54 541 4.9E-214 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS30760 152025b74dd50e9179c665dd488c7bac 155 SUPERFAMILY SSF46894 6 59 4.42E-8 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS30760 152025b74dd50e9179c665dd488c7bac 155 Pfam PF00196 Bacterial regulatory proteins, luxR family 10 53 2.5E-6 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS30760 152025b74dd50e9179c665dd488c7bac 155 Gene3D G3DSA:1.10.10.10 8 65 1.7E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS30760 152025b74dd50e9179c665dd488c7bac 155 Gene3D G3DSA:1.10.10.10 85 145 8.2E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS30760 152025b74dd50e9179c665dd488c7bac 155 SMART SM00421 82 139 0.0082 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS30760 152025b74dd50e9179c665dd488c7bac 155 SMART SM00421 8 66 0.0012 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS30760 152025b74dd50e9179c665dd488c7bac 155 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 41 53 3.3E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS30760 152025b74dd50e9179c665dd488c7bac 155 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 11 25 3.3E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS30760 152025b74dd50e9179c665dd488c7bac 155 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 25 41 3.3E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS30760 152025b74dd50e9179c665dd488c7bac 155 SUPERFAMILY SSF46894 73 145 2.55E-7 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS10775 ec6c7cab41f0b7aac3bf2104e3420843 263 SUPERFAMILY SSF55909 6 254 6.48E-52 T 23-04-2016 DC74_RS10775 ec6c7cab41f0b7aac3bf2104e3420843 263 PANTHER PTHR12737:SF9 1 260 2.9E-61 T 23-04-2016 DC74_RS10775 ec6c7cab41f0b7aac3bf2104e3420843 263 PANTHER PTHR12737 1 260 2.9E-61 T 23-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS10775 ec6c7cab41f0b7aac3bf2104e3420843 263 Gene3D G3DSA:3.75.10.10 4 253 1.4E-61 T 23-04-2016 DC74_RS10775 ec6c7cab41f0b7aac3bf2104e3420843 263 Pfam PF02274 Amidinotransferase 30 204 1.1E-9 T 23-04-2016 DC74_RS17725 3f7e6b1018bb01c4595af5cc18cdac05 267 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 264 1.2E-73 T 23-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 DC74_RS17725 3f7e6b1018bb01c4595af5cc18cdac05 267 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 4 263 3.7E-72 T 23-04-2016 DC74_RS17725 3f7e6b1018bb01c4595af5cc18cdac05 267 Gene3D G3DSA:3.60.10.10 1 265 5.7E-91 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS17725 3f7e6b1018bb01c4595af5cc18cdac05 267 SUPERFAMILY SSF56219 2 264 3.14E-72 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS17725 3f7e6b1018bb01c4595af5cc18cdac05 267 PANTHER PTHR22748 1 263 1.0E-90 T 23-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 DC74_RS17725 3f7e6b1018bb01c4595af5cc18cdac05 267 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 258 1.5E-27 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS36530 8ec8999f714a2fd050fc2d3be28f17c3 423 SUPERFAMILY SSF52777 6 202 3.22E-22 T 23-04-2016 DC74_RS36530 8ec8999f714a2fd050fc2d3be28f17c3 423 Pfam PF00668 Condensation domain 42 274 7.8E-19 T 23-04-2016 IPR001242 Condensation domain DC74_RS36530 8ec8999f714a2fd050fc2d3be28f17c3 423 SUPERFAMILY SSF52777 188 369 1.22E-12 T 23-04-2016 DC74_RS26950 79f1813ef9baf50c3bbb5efb6a2be831 127 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 122 18.723 T 23-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26950 79f1813ef9baf50c3bbb5efb6a2be831 127 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 17 92 1.0E-28 T 23-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26950 79f1813ef9baf50c3bbb5efb6a2be831 127 SUPERFAMILY SSF51344 4 87 3.92E-19 T 23-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26950 79f1813ef9baf50c3bbb5efb6a2be831 127 Gene3D G3DSA:2.60.15.10 3 90 3.3E-23 T 23-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26950 79f1813ef9baf50c3bbb5efb6a2be831 127 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 86 3.3E-22 T 23-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26950 79f1813ef9baf50c3bbb5efb6a2be831 127 Gene3D G3DSA:1.20.5.440 91 104 8.2E-4 T 23-04-2016 DC74_RS26950 79f1813ef9baf50c3bbb5efb6a2be831 127 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 116 7.0E-25 T 23-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26950 79f1813ef9baf50c3bbb5efb6a2be831 127 PANTHER PTHR13822 3 122 3.5E-27 T 23-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 Pfam PF14759 Reductase C-terminal 328 417 3.1E-23 T 23-04-2016 IPR028202 Reductase, C-terminal DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 SUPERFAMILY SSF55424 322 418 4.26E-26 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 SUPERFAMILY SSF51905 12 196 1.57E-40 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 16 38 3.4E-11 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 3.4E-11 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 235 256 3.4E-11 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 271 289 3.4E-11 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 148 172 3.4E-11 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 Gene3D G3DSA:3.50.50.60 14 113 1.3E-27 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 PANTHER PTHR22912 1 403 2.3E-119 T 23-04-2016 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 PANTHER PTHR22912:SF180 1 403 2.3E-119 T 23-04-2016 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 5.1E-28 T 23-04-2016 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 5.1E-28 T 23-04-2016 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 5.1E-28 T 23-04-2016 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 5.1E-28 T 23-04-2016 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 5.1E-28 T 23-04-2016 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 Gene3D G3DSA:3.50.50.60 114 314 4.7E-46 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 16 302 8.1E-57 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 Gene3D G3DSA:3.30.390.30 328 418 4.4E-28 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS12665 aa283923ee6aaa273d9e92d8c10b72a4 419 SUPERFAMILY SSF51905 150 315 3.15E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17140 960a9b9a787204fb8737fe6ecb6d6cdf 195 Gene3D G3DSA:3.40.50.7700 18 180 1.9E-74 T 23-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 DC74_RS17140 960a9b9a787204fb8737fe6ecb6d6cdf 195 SUPERFAMILY SSF52255 23 183 3.92E-66 T 23-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 DC74_RS17140 960a9b9a787204fb8737fe6ecb6d6cdf 195 PANTHER PTHR11609:SF5 23 186 1.4E-87 T 23-04-2016 DC74_RS17140 960a9b9a787204fb8737fe6ecb6d6cdf 195 PANTHER PTHR11609 23 186 1.4E-87 T 23-04-2016 DC74_RS17140 960a9b9a787204fb8737fe6ecb6d6cdf 195 PIRSF PIRSF001338 20 183 2.3E-68 T 23-04-2016 IPR024694 N5-carboxyaminoimidazole ribonucleotide mutase PurE GO:0006189|GO:0034023 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234|UniPathway: UPA00074 DC74_RS17140 960a9b9a787204fb8737fe6ecb6d6cdf 195 SMART SM01001 23 172 2.1E-97 T 23-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 DC74_RS17140 960a9b9a787204fb8737fe6ecb6d6cdf 195 Pfam PF00731 AIR carboxylase 25 170 1.0E-65 T 23-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 DC74_RS17140 960a9b9a787204fb8737fe6ecb6d6cdf 195 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 25 176 32.458 T 23-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 DC74_RS17140 960a9b9a787204fb8737fe6ecb6d6cdf 195 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 25 179 7.0E-65 T 23-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 DC74_RS09880 3bb3c875fbf656266731b4a878e9094b 398 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 23-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09880 3bb3c875fbf656266731b4a878e9094b 398 SUPERFAMILY SSF52402 3 166 3.31E-42 T 23-04-2016 DC74_RS09880 3bb3c875fbf656266731b4a878e9094b 398 PANTHER PTHR11587:SF2 3 394 2.7E-180 T 23-04-2016 DC74_RS09880 3bb3c875fbf656266731b4a878e9094b 398 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 396 51.16 T 23-04-2016 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09880 3bb3c875fbf656266731b4a878e9094b 398 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 23-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09880 3bb3c875fbf656266731b4a878e9094b 398 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 392 6.1E-143 T 23-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09880 3bb3c875fbf656266731b4a878e9094b 398 Gene3D G3DSA:3.40.50.620 3 173 1.4E-55 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS09880 3bb3c875fbf656266731b4a878e9094b 398 SUPERFAMILY SSF69864 171 394 1.27E-80 T 23-04-2016 DC74_RS09880 3bb3c875fbf656266731b4a878e9094b 398 Gene3D G3DSA:3.90.1260.10 174 394 8.1E-79 T 23-04-2016 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09880 3bb3c875fbf656266731b4a878e9094b 398 Pfam PF00764 Arginosuccinate synthase 6 391 4.1E-180 T 23-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09880 3bb3c875fbf656266731b4a878e9094b 398 PANTHER PTHR11587 3 394 2.7E-180 T 23-04-2016 DC74_RS22995 29781cc0f23af285c54da7d94347e850 704 Gene3D G3DSA:3.30.420.10 362 465 2.7E-22 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS22995 29781cc0f23af285c54da7d94347e850 704 Gene3D G3DSA:3.30.420.10 259 328 2.7E-22 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS22995 29781cc0f23af285c54da7d94347e850 704 Pfam PF00665 Integrase core domain 258 413 3.7E-12 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 DC74_RS22995 29781cc0f23af285c54da7d94347e850 704 Pfam PF09299 Mu transposase, C-terminal 502 565 1.0E-8 T 23-04-2016 IPR015378 Transposase-like, Mu, C-terminal DC74_RS22995 29781cc0f23af285c54da7d94347e850 704 SUPERFAMILY SSF53098 358 469 2.06E-13 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS22995 29781cc0f23af285c54da7d94347e850 704 SUPERFAMILY SSF53098 256 322 2.06E-13 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS12360 03fd3a756082adf5254da54bfb006554 251 Gene3D G3DSA:3.20.20.70 6 251 8.3E-102 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS12360 03fd3a756082adf5254da54bfb006554 251 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 251 1.8E-108 T 23-04-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 DC74_RS12360 03fd3a756082adf5254da54bfb006554 251 PANTHER PTHR21235:SF2 3 251 1.5E-119 T 23-04-2016 DC74_RS12360 03fd3a756082adf5254da54bfb006554 251 Pfam PF00977 Histidine biosynthesis protein 6 234 1.7E-87 T 23-04-2016 IPR006062 Histidine biosynthesis GO:0000105 DC74_RS12360 03fd3a756082adf5254da54bfb006554 251 PANTHER PTHR21235 3 251 1.5E-119 T 23-04-2016 DC74_RS12360 03fd3a756082adf5254da54bfb006554 251 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 251 47.529 T 23-04-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 DC74_RS12360 03fd3a756082adf5254da54bfb006554 251 SUPERFAMILY SSF51366 3 251 6.83E-83 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 DC74_RS34405 da6e0ea7badb2e2015942ed3f1bf8a62 291 SUPERFAMILY SSF56219 18 288 1.22E-19 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS34405 da6e0ea7badb2e2015942ed3f1bf8a62 291 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 20 281 1.1E-7 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS34405 da6e0ea7badb2e2015942ed3f1bf8a62 291 Gene3D G3DSA:3.60.10.10 30 289 1.1E-7 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS12485 6606208ad8b38e399ca4dad104662f48 200 Pfam PF01252 Signal peptidase (SPase) II 51 188 5.7E-28 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS12485 6606208ad8b38e399ca4dad104662f48 200 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 97 3.6E-15 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS12485 6606208ad8b38e399ca4dad104662f48 200 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 169 185 3.6E-15 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS12485 6606208ad8b38e399ca4dad104662f48 200 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 131 146 3.6E-15 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS12485 6606208ad8b38e399ca4dad104662f48 200 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 42 194 14.613 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS12485 6606208ad8b38e399ca4dad104662f48 200 ProSitePatterns PS00855 Signal peptidases II signature. 134 146 - T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS12485 6606208ad8b38e399ca4dad104662f48 200 PANTHER PTHR33695 22 194 3.8E-43 T 23-04-2016 DC74_RS12485 6606208ad8b38e399ca4dad104662f48 200 PANTHER PTHR33695:SF1 22 194 3.8E-43 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS12485 6606208ad8b38e399ca4dad104662f48 200 TIGRFAM TIGR00077 lspA: signal peptidase II 47 188 1.3E-21 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 DC74_RS29690 552822e4a7a9def66aeb4cc8f26b785d 481 Gene3D G3DSA:3.40.50.620 4 175 6.8E-41 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS29690 552822e4a7a9def66aeb4cc8f26b785d 481 SUPERFAMILY SSF69864 190 433 4.05E-74 T 23-04-2016 DC74_RS29690 552822e4a7a9def66aeb4cc8f26b785d 481 Gene3D G3DSA:1.10.287.400 377 434 1.0E-28 T 23-04-2016 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS29690 552822e4a7a9def66aeb4cc8f26b785d 481 PANTHER PTHR11587:SF2 1 426 1.1E-161 T 23-04-2016 DC74_RS29690 552822e4a7a9def66aeb4cc8f26b785d 481 Pfam PF00764 Arginosuccinate synthase 16 394 7.0E-56 T 23-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS29690 552822e4a7a9def66aeb4cc8f26b785d 481 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 420 1.4E-137 T 23-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS29690 552822e4a7a9def66aeb4cc8f26b785d 481 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 23-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS29690 552822e4a7a9def66aeb4cc8f26b785d 481 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 23-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS29690 552822e4a7a9def66aeb4cc8f26b785d 481 SUPERFAMILY SSF52402 4 185 1.13E-31 T 23-04-2016 DC74_RS29690 552822e4a7a9def66aeb4cc8f26b785d 481 PANTHER PTHR11587 1 426 1.1E-161 T 23-04-2016 DC74_RS29690 552822e4a7a9def66aeb4cc8f26b785d 481 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 472 80.175 T 23-04-2016 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS29690 552822e4a7a9def66aeb4cc8f26b785d 481 Gene3D G3DSA:3.90.1260.10 176 372 1.9E-61 T 23-04-2016 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS01555 ddbe11b87011743fbd0d0e9ca1270e0c 170 PANTHER PTHR33164 50 170 2.9E-17 T 23-04-2016 DC74_RS01555 ddbe11b87011743fbd0d0e9ca1270e0c 170 SUPERFAMILY SSF46785 27 163 1.58E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01555 ddbe11b87011743fbd0d0e9ca1270e0c 170 Gene3D G3DSA:1.10.10.10 24 161 7.2E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01555 ddbe11b87011743fbd0d0e9ca1270e0c 170 Pfam PF01047 MarR family 67 112 2.4E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS01555 ddbe11b87011743fbd0d0e9ca1270e0c 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 103 1.7E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS01555 ddbe11b87011743fbd0d0e9ca1270e0c 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 137 157 1.7E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS01555 ddbe11b87011743fbd0d0e9ca1270e0c 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 123 1.7E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS01555 ddbe11b87011743fbd0d0e9ca1270e0c 170 SMART SM00347 47 147 1.8E-15 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS03480 f4f15cb6b49c7b2b0a8d3a94ed8f1293 88 SUPERFAMILY SSF69318 33 66 4.19E-5 T 23-04-2016 DC74_RS03480 f4f15cb6b49c7b2b0a8d3a94ed8f1293 88 Gene3D G3DSA:2.130.10.130 35 66 8.8E-4 T 23-04-2016 DC74_RS40680 3623d21e174080314dea0a479ceb78e0 328 Pfam PF00069 Protein kinase domain 17 260 4.4E-34 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS40680 3623d21e174080314dea0a479ceb78e0 328 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 44 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS40680 3623d21e174080314dea0a479ceb78e0 328 SUPERFAMILY SSF56112 6 262 9.58E-56 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS40680 3623d21e174080314dea0a479ceb78e0 328 SMART SM00220 16 264 8.5E-34 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS40680 3623d21e174080314dea0a479ceb78e0 328 PANTHER PTHR24362 9 268 6.6E-73 T 23-04-2016 DC74_RS40680 3623d21e174080314dea0a479ceb78e0 328 PANTHER PTHR24362:SF247 9 268 6.6E-73 T 23-04-2016 DC74_RS40680 3623d21e174080314dea0a479ceb78e0 328 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS40680 3623d21e174080314dea0a479ceb78e0 328 Gene3D G3DSA:3.30.200.20 7 86 7.2E-13 T 23-04-2016 DC74_RS40680 3623d21e174080314dea0a479ceb78e0 328 Gene3D G3DSA:1.10.510.10 87 262 6.8E-36 T 23-04-2016 DC74_RS06850 d38d72bd87e7788ef823538b4444caa9 909 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 849 863 1.3E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06850 d38d72bd87e7788ef823538b4444caa9 909 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 879 891 1.3E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06850 d38d72bd87e7788ef823538b4444caa9 909 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 863 879 1.3E-5 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06850 d38d72bd87e7788ef823538b4444caa9 909 SUPERFAMILY SSF46894 839 903 7.48E-13 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS06850 d38d72bd87e7788ef823538b4444caa9 909 Pfam PF13191 AAA ATPase domain 7 152 4.3E-12 T 23-04-2016 DC74_RS06850 d38d72bd87e7788ef823538b4444caa9 909 ProSitePatterns PS00622 LuxR-type HTH domain signature. 863 890 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06850 d38d72bd87e7788ef823538b4444caa9 909 Gene3D G3DSA:1.25.40.10 513 763 5.4E-12 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS06850 d38d72bd87e7788ef823538b4444caa9 909 Gene3D G3DSA:1.10.10.10 843 903 4.5E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06850 d38d72bd87e7788ef823538b4444caa9 909 SMART SM00421 846 903 1.7E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06850 d38d72bd87e7788ef823538b4444caa9 909 Pfam PF00196 Bacterial regulatory proteins, luxR family 848 899 4.2E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS06850 d38d72bd87e7788ef823538b4444caa9 909 SUPERFAMILY SSF48452 669 742 3.13E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS06850 d38d72bd87e7788ef823538b4444caa9 909 SUPERFAMILY SSF48452 519 623 3.13E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS33610 80a2eac18c6d4350568b859ee253e8fb 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 6 62 4.8E-13 T 23-04-2016 DC74_RS33610 80a2eac18c6d4350568b859ee253e8fb 64 SUPERFAMILY SSF54862 2 62 7.04E-13 T 23-04-2016 DC74_RS33610 80a2eac18c6d4350568b859ee253e8fb 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 3.6E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS33610 80a2eac18c6d4350568b859ee253e8fb 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 3.6E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS33610 80a2eac18c6d4350568b859ee253e8fb 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 3.6E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS33610 80a2eac18c6d4350568b859ee253e8fb 64 PANTHER PTHR36923:SF1 1 64 1.2E-17 T 23-04-2016 DC74_RS33610 80a2eac18c6d4350568b859ee253e8fb 64 Gene3D G3DSA:3.30.70.20 1 64 2.0E-16 T 23-04-2016 DC74_RS33610 80a2eac18c6d4350568b859ee253e8fb 64 PANTHER PTHR36923 1 64 1.2E-17 T 23-04-2016 DC74_RS24860 b298241d4e56e85e452182e8fafbeb67 401 SUPERFAMILY SSF47413 10 76 3.75E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS24860 b298241d4e56e85e452182e8fafbeb67 401 SMART SM00530 15 70 6.3E-11 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS24860 b298241d4e56e85e452182e8fafbeb67 401 Pfam PF13560 Helix-turn-helix domain 11 68 1.7E-9 T 23-04-2016 DC74_RS24860 b298241d4e56e85e452182e8fafbeb67 401 Gene3D G3DSA:1.10.260.40 6 76 7.8E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS15000 f225b712380454013845f26961f78007 301 Gene3D G3DSA:3.60.15.10 5 300 6.3E-73 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS15000 f225b712380454013845f26961f78007 301 SUPERFAMILY SSF56281 5 297 1.28E-62 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS15000 f225b712380454013845f26961f78007 301 PANTHER PTHR12553 5 152 3.5E-74 T 23-04-2016 DC74_RS15000 f225b712380454013845f26961f78007 301 PANTHER PTHR12553 168 300 3.5E-74 T 23-04-2016 DC74_RS15000 f225b712380454013845f26961f78007 301 Pfam PF12706 Beta-lactamase superfamily domain 34 263 8.7E-16 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS15000 f225b712380454013845f26961f78007 301 Hamap MF_01818 Ribonuclease BN [rbn]. 4 297 30.881 T 23-04-2016 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 DC74_RS33820 d1cb8c5ec384462cb6bf8bda65b3dcd1 439 SUPERFAMILY SSF103473 12 411 3.27E-52 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS33820 d1cb8c5ec384462cb6bf8bda65b3dcd1 439 Pfam PF07690 Major Facilitator Superfamily 29 265 1.8E-18 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS33820 d1cb8c5ec384462cb6bf8bda65b3dcd1 439 Gene3D G3DSA:1.20.1250.20 229 416 1.7E-22 T 23-04-2016 DC74_RS33820 d1cb8c5ec384462cb6bf8bda65b3dcd1 439 Gene3D G3DSA:1.20.1250.20 20 205 2.5E-23 T 23-04-2016 DC74_RS21490 37b67313537d219f84fa7fd0909dc687 233 SMART SM00448 8 119 1.6E-39 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS21490 37b67313537d219f84fa7fd0909dc687 233 SUPERFAMILY SSF52172 6 189 5.57E-40 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS21490 37b67313537d219f84fa7fd0909dc687 233 Gene3D G3DSA:3.40.50.2300 3 126 1.2E-37 T 23-04-2016 DC74_RS21490 37b67313537d219f84fa7fd0909dc687 233 PANTHER PTHR26402:SF316 8 232 8.7E-99 T 23-04-2016 DC74_RS21490 37b67313537d219f84fa7fd0909dc687 233 Pfam PF00072 Response regulator receiver domain 10 119 1.7E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS21490 37b67313537d219f84fa7fd0909dc687 233 SMART SM00862 155 229 9.4E-26 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS21490 37b67313537d219f84fa7fd0909dc687 233 Gene3D G3DSA:1.10.10.10 133 230 1.0E-35 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21490 37b67313537d219f84fa7fd0909dc687 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 228 6.2E-25 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS21490 37b67313537d219f84fa7fd0909dc687 233 PANTHER PTHR26402 8 232 8.7E-99 T 23-04-2016 DC74_RS26305 eae7ac36439939a46457fc428ee82fd0 254 SMART SM00382 24 210 3.0E-20 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS26305 eae7ac36439939a46457fc428ee82fd0 254 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS26305 eae7ac36439939a46457fc428ee82fd0 254 PANTHER PTHR24220:SF10 1 215 2.8E-79 T 23-04-2016 DC74_RS26305 eae7ac36439939a46457fc428ee82fd0 254 PANTHER PTHR24220 1 215 2.8E-79 T 23-04-2016 DC74_RS26305 eae7ac36439939a46457fc428ee82fd0 254 SUPERFAMILY SSF52540 10 220 6.84E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26305 eae7ac36439939a46457fc428ee82fd0 254 Pfam PF00005 ABC transporter 17 151 9.5E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS26305 eae7ac36439939a46457fc428ee82fd0 254 Gene3D G3DSA:3.40.50.300 12 209 1.2E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS13405 b197bac60f6e7f96fa239c3bd242c9b8 285 PANTHER PTHR10804 4 283 1.2E-142 T 23-04-2016 DC74_RS13405 b197bac60f6e7f96fa239c3bd242c9b8 285 Pfam PF00557 Metallopeptidase family M24 48 276 1.4E-54 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS13405 b197bac60f6e7f96fa239c3bd242c9b8 285 SUPERFAMILY SSF55920 6 284 1.96E-88 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS13405 b197bac60f6e7f96fa239c3bd242c9b8 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 23-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 DC74_RS13405 b197bac60f6e7f96fa239c3bd242c9b8 285 Gene3D G3DSA:3.90.230.10 41 284 9.3E-97 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS13405 b197bac60f6e7f96fa239c3bd242c9b8 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 1.5E-20 T 23-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase DC74_RS13405 b197bac60f6e7f96fa239c3bd242c9b8 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 1.5E-20 T 23-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase DC74_RS13405 b197bac60f6e7f96fa239c3bd242c9b8 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.5E-20 T 23-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase DC74_RS13405 b197bac60f6e7f96fa239c3bd242c9b8 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 1.5E-20 T 23-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase DC74_RS13405 b197bac60f6e7f96fa239c3bd242c9b8 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 40.152 T 23-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 DC74_RS13405 b197bac60f6e7f96fa239c3bd242c9b8 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 41 283 9.8E-92 T 23-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 DC74_RS13405 b197bac60f6e7f96fa239c3bd242c9b8 285 PANTHER PTHR10804:SF82 4 283 1.2E-142 T 23-04-2016 DC74_RS05180 309d6b168bc415febd4c4ba39b79d193 403 Pfam PF00482 Type II secretion system (T2SS), protein F 270 390 7.5E-25 T 23-04-2016 IPR018076 Type II secretion system F domain DC74_RS05180 309d6b168bc415febd4c4ba39b79d193 403 Pfam PF00482 Type II secretion system (T2SS), protein F 67 190 9.6E-27 T 23-04-2016 IPR018076 Type II secretion system F domain DC74_RS05180 309d6b168bc415febd4c4ba39b79d193 403 PANTHER PTHR30012:SF0 2 401 2.1E-114 T 23-04-2016 DC74_RS05180 309d6b168bc415febd4c4ba39b79d193 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 162 190 4.0E-15 T 23-04-2016 IPR003004 GspF/PilC family DC74_RS05180 309d6b168bc415febd4c4ba39b79d193 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 365 379 4.0E-15 T 23-04-2016 IPR003004 GspF/PilC family DC74_RS05180 309d6b168bc415febd4c4ba39b79d193 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 63 75 4.0E-15 T 23-04-2016 IPR003004 GspF/PilC family DC74_RS05180 309d6b168bc415febd4c4ba39b79d193 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 381 400 4.0E-15 T 23-04-2016 IPR003004 GspF/PilC family DC74_RS05180 309d6b168bc415febd4c4ba39b79d193 403 PANTHER PTHR30012 2 401 2.1E-114 T 23-04-2016 DC74_RS16845 1bb55910c10499882b338ded1f9c857f 417 PANTHER PTHR30528 14 408 8.7E-112 T 23-04-2016 DC74_RS16845 1bb55910c10499882b338ded1f9c857f 417 Pfam PF06224 Winged helix DNA-binding domain 46 379 5.1E-60 T 23-04-2016 IPR009351 Protein of unknown function DUF1006 DC74_RS28200 28352421d3f399096a2a7ba254099dd0 256 PIRSF PIRSF005650 15 256 1.2E-90 T 23-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 DC74_RS28200 28352421d3f399096a2a7ba254099dd0 256 Gene3D G3DSA:3.40.1160.10 19 250 9.0E-83 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 DC74_RS28200 28352421d3f399096a2a7ba254099dd0 256 PANTHER PTHR21499:SF23 19 252 2.0E-111 T 23-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 DC74_RS28200 28352421d3f399096a2a7ba254099dd0 256 PANTHER PTHR21499 19 252 2.0E-111 T 23-04-2016 DC74_RS28200 28352421d3f399096a2a7ba254099dd0 256 Pfam PF00696 Amino acid kinase family 20 228 1.7E-26 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 DC74_RS28200 28352421d3f399096a2a7ba254099dd0 256 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 19 250 1.0E-92 T 23-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 DC74_RS28200 28352421d3f399096a2a7ba254099dd0 256 SUPERFAMILY SSF53633 19 251 3.01E-69 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 DC74_RS28200 28352421d3f399096a2a7ba254099dd0 256 Hamap MF_01220_B Uridylate kinase [pyrH]. 16 250 43.274 T 23-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 DC74_RS07885 e5f4f1309bdbf6876cdbe829ff8631fa 478 SUPERFAMILY SSF103473 258 470 8.63E-48 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS07885 e5f4f1309bdbf6876cdbe829ff8631fa 478 SUPERFAMILY SSF103473 24 211 8.63E-48 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS07885 e5f4f1309bdbf6876cdbe829ff8631fa 478 PANTHER PTHR23501 7 470 9.2E-62 T 23-04-2016 DC74_RS07885 e5f4f1309bdbf6876cdbe829ff8631fa 478 Gene3D G3DSA:1.20.1250.20 273 470 2.7E-8 T 23-04-2016 DC74_RS07885 e5f4f1309bdbf6876cdbe829ff8631fa 478 Pfam PF07690 Major Facilitator Superfamily 31 423 5.8E-35 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS07885 e5f4f1309bdbf6876cdbe829ff8631fa 478 Gene3D G3DSA:1.20.1250.20 25 201 2.0E-23 T 23-04-2016 DC74_RS19715 e282ce1b397096378eae78d6de11bbb6 179 Pfam PF12840 Helix-turn-helix domain 101 156 1.3E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19715 e282ce1b397096378eae78d6de11bbb6 179 SUPERFAMILY SSF46785 90 160 4.46E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19715 e282ce1b397096378eae78d6de11bbb6 179 Gene3D G3DSA:1.10.10.10 95 160 1.5E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19495 a2e135841310c8e56b5d36578ca40080 384 Pfam PF00850 Histone deacetylase domain 15 310 7.4E-69 T 23-04-2016 IPR023801 Histone deacetylase domain DC74_RS19495 a2e135841310c8e56b5d36578ca40080 384 PRINTS PR01272 Acetoin utilisation ACUC protein signature 99 112 3.8E-8 T 23-04-2016 IPR003085 Acetoin utilization protein AcuC GO:0045149 UniPathway: UPA00040 DC74_RS19495 a2e135841310c8e56b5d36578ca40080 384 PRINTS PR01272 Acetoin utilisation ACUC protein signature 78 92 3.8E-8 T 23-04-2016 IPR003085 Acetoin utilization protein AcuC GO:0045149 UniPathway: UPA00040 DC74_RS19495 a2e135841310c8e56b5d36578ca40080 384 PRINTS PR01272 Acetoin utilisation ACUC protein signature 9 29 3.8E-8 T 23-04-2016 IPR003085 Acetoin utilization protein AcuC GO:0045149 UniPathway: UPA00040 DC74_RS19495 a2e135841310c8e56b5d36578ca40080 384 PRINTS PR01270 Histone deacetylase superfamily signature 122 145 8.9E-18 T 23-04-2016 IPR000286 Histone deacetylase superfamily DC74_RS19495 a2e135841310c8e56b5d36578ca40080 384 PRINTS PR01270 Histone deacetylase superfamily signature 155 170 8.9E-18 T 23-04-2016 IPR000286 Histone deacetylase superfamily DC74_RS19495 a2e135841310c8e56b5d36578ca40080 384 PRINTS PR01270 Histone deacetylase superfamily signature 241 251 8.9E-18 T 23-04-2016 IPR000286 Histone deacetylase superfamily DC74_RS19495 a2e135841310c8e56b5d36578ca40080 384 PANTHER PTHR10625 9 338 1.9E-113 T 23-04-2016 IPR000286 Histone deacetylase superfamily DC74_RS19495 a2e135841310c8e56b5d36578ca40080 384 PANTHER PTHR10625:SF10 9 338 1.9E-113 T 23-04-2016 DC74_RS19495 a2e135841310c8e56b5d36578ca40080 384 Gene3D G3DSA:3.40.800.20 2 343 3.0E-85 T 23-04-2016 IPR023801 Histone deacetylase domain DC74_RS19495 a2e135841310c8e56b5d36578ca40080 384 SUPERFAMILY SSF52768 2 345 2.78E-96 T 23-04-2016 DC74_RS12515 0671cbfac71d11386ad5ce46f2239ca1 206 Pfam PF04472 Protein of unknown function (DUF552) 118 189 3.3E-27 T 23-04-2016 IPR007561 Cell division protein SepF/SepF-related GO:0000917 DC74_RS12515 0671cbfac71d11386ad5ce46f2239ca1 206 PANTHER PTHR35798:SF1 35 205 3.7E-35 T 23-04-2016 DC74_RS12515 0671cbfac71d11386ad5ce46f2239ca1 206 Hamap MF_01197 Cell division protein SepF [sepF]. 2 197 22.514 T 23-04-2016 IPR023052 Cell division protein SepF GO:0090529 DC74_RS12515 0671cbfac71d11386ad5ce46f2239ca1 206 PANTHER PTHR35798 35 205 3.7E-35 T 23-04-2016 DC74_RS27090 9c31fc5dff39416b3d1fa3cd61a672d1 107 SUPERFAMILY SSF52091 2 99 2.75E-21 T 23-04-2016 IPR002645 STAS domain DC74_RS27090 9c31fc5dff39416b3d1fa3cd61a672d1 107 Pfam PF13466 STAS domain 10 89 5.9E-15 T 23-04-2016 IPR002645 STAS domain DC74_RS27090 9c31fc5dff39416b3d1fa3cd61a672d1 107 Gene3D G3DSA:3.30.750.24 2 100 5.4E-26 T 23-04-2016 IPR002645 STAS domain DC74_RS27090 9c31fc5dff39416b3d1fa3cd61a672d1 107 PANTHER PTHR33495 1 95 5.9E-22 T 23-04-2016 DC74_RS27090 9c31fc5dff39416b3d1fa3cd61a672d1 107 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 99 9.2E-17 T 23-04-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 DC74_RS27090 9c31fc5dff39416b3d1fa3cd61a672d1 107 PANTHER PTHR33495:SF2 1 95 5.9E-22 T 23-04-2016 DC74_RS20855 adcf43ba3a4e641fd2db2bb29cb11042 116 PANTHER PTHR33204 1 103 2.5E-25 T 23-04-2016 DC74_RS20855 adcf43ba3a4e641fd2db2bb29cb11042 116 Pfam PF01638 HxlR-like helix-turn-helix 21 104 4.6E-19 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS20855 adcf43ba3a4e641fd2db2bb29cb11042 116 SUPERFAMILY SSF46785 11 109 1.98E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20855 adcf43ba3a4e641fd2db2bb29cb11042 116 Gene3D G3DSA:1.10.10.10 6 108 2.5E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20855 adcf43ba3a4e641fd2db2bb29cb11042 116 PANTHER PTHR33204:SF6 1 103 2.5E-25 T 23-04-2016 DC74_RS22680 fff4d232c45e3d3719b46709f033f773 194 PANTHER PTHR14969:SF24 32 167 4.6E-23 T 23-04-2016 DC74_RS22680 fff4d232c45e3d3719b46709f033f773 194 Pfam PF01569 PAP2 superfamily 60 171 1.8E-19 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS22680 fff4d232c45e3d3719b46709f033f773 194 PANTHER PTHR14969 32 167 4.6E-23 T 23-04-2016 DC74_RS22680 fff4d232c45e3d3719b46709f033f773 194 Gene3D G3DSA:1.20.144.10 14 170 2.2E-29 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS22680 fff4d232c45e3d3719b46709f033f773 194 SMART SM00014 55 169 1.8E-12 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS22680 fff4d232c45e3d3719b46709f033f773 194 SUPERFAMILY SSF48317 17 173 1.1E-30 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS11770 13d7db19ff21a44dc7ca52e1179d528a 285 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 1 283 18.346 T 23-04-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 UniPathway: UPA00834 DC74_RS11770 13d7db19ff21a44dc7ca52e1179d528a 285 Pfam PF01040 UbiA prenyltransferase family 12 268 1.8E-63 T 23-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 DC74_RS11770 13d7db19ff21a44dc7ca52e1179d528a 285 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 51 73 - T 23-04-2016 IPR030470 UbiA prenyltransferase conserved site DC74_RS11770 13d7db19ff21a44dc7ca52e1179d528a 285 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 1 281 2.9E-94 T 23-04-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 UniPathway: UPA00834 DC74_RS11770 13d7db19ff21a44dc7ca52e1179d528a 285 PANTHER PTHR11048 1 285 3.8E-72 T 23-04-2016 DC74_RS38825 beb9fd3f0f6f839791e241eb604e0cee 328 SUPERFAMILY SSF53686 21 309 5.5E-64 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS38825 beb9fd3f0f6f839791e241eb604e0cee 328 PANTHER PTHR10314:SF109 27 308 1.2E-66 T 23-04-2016 DC74_RS38825 beb9fd3f0f6f839791e241eb604e0cee 328 Gene3D G3DSA:3.40.50.1100 35 136 2.6E-19 T 23-04-2016 DC74_RS38825 beb9fd3f0f6f839791e241eb604e0cee 328 Gene3D G3DSA:3.40.50.1100 137 306 5.0E-47 T 23-04-2016 DC74_RS38825 beb9fd3f0f6f839791e241eb604e0cee 328 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 280 5.8E-45 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS38825 beb9fd3f0f6f839791e241eb604e0cee 328 PANTHER PTHR10314 27 308 1.2E-66 T 23-04-2016 DC74_RS38825 beb9fd3f0f6f839791e241eb604e0cee 328 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 10 307 1.7E-115 T 23-04-2016 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 Gene3D G3DSA:2.40.10.10 155 254 2.5E-35 T 23-04-2016 DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 Gene3D G3DSA:2.40.10.10 45 74 6.7E-13 T 23-04-2016 DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 210 221 - T 23-04-2016 IPR033116 Serine proteases, trypsin family, serine active site DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 SMART SM00020 44 260 2.6E-60 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 Pfam PF00089 Trypsin 45 257 4.1E-48 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 Gene3D G3DSA:2.40.10.10 124 154 9.2E-4 T 23-04-2016 DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 PANTHER PTHR24276 12 256 1.7E-62 T 23-04-2016 DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 SUPERFAMILY SSF50494 43 262 1.27E-58 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 67 82 5.8E-12 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 209 221 5.8E-12 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 122 136 5.8E-12 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 77 82 - T 23-04-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 DC74_RS12210 67b4deb3d313d723f8e25a4b322b4cf8 268 Gene3D G3DSA:2.40.10.10 75 123 8.1E-13 T 23-04-2016 DC74_RS35780 b44d7000d8352b5c7b0249cef68a1cf9 298 Gene3D G3DSA:1.10.1040.10 168 296 2.8E-40 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS35780 b44d7000d8352b5c7b0249cef68a1cf9 298 SUPERFAMILY SSF51735 5 165 1.05E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS35780 b44d7000d8352b5c7b0249cef68a1cf9 298 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 6 294 1.2E-139 T 23-04-2016 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 DC74_RS35780 b44d7000d8352b5c7b0249cef68a1cf9 298 Gene3D G3DSA:3.40.50.720 5 166 2.6E-59 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS35780 b44d7000d8352b5c7b0249cef68a1cf9 298 SUPERFAMILY SSF48179 166 295 3.4E-36 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS35780 b44d7000d8352b5c7b0249cef68a1cf9 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 165 1.5E-51 T 23-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 DC74_RS35780 b44d7000d8352b5c7b0249cef68a1cf9 298 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 286 1.1E-37 T 23-04-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 DC74_RS35780 b44d7000d8352b5c7b0249cef68a1cf9 298 PANTHER PTHR22981 1 297 2.9E-118 T 23-04-2016 DC74_RS35780 b44d7000d8352b5c7b0249cef68a1cf9 298 PIRSF PIRSF000103 1 295 2.9E-81 T 23-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 DC74_RS35780 b44d7000d8352b5c7b0249cef68a1cf9 298 PANTHER PTHR22981:SF70 1 297 2.9E-118 T 23-04-2016 DC74_RS31320 b44d7000d8352b5c7b0249cef68a1cf9 298 Gene3D G3DSA:1.10.1040.10 168 296 2.8E-40 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS31320 b44d7000d8352b5c7b0249cef68a1cf9 298 SUPERFAMILY SSF51735 5 165 1.05E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31320 b44d7000d8352b5c7b0249cef68a1cf9 298 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 6 294 1.2E-139 T 23-04-2016 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 DC74_RS31320 b44d7000d8352b5c7b0249cef68a1cf9 298 Gene3D G3DSA:3.40.50.720 5 166 2.6E-59 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31320 b44d7000d8352b5c7b0249cef68a1cf9 298 SUPERFAMILY SSF48179 166 295 3.4E-36 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS31320 b44d7000d8352b5c7b0249cef68a1cf9 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 165 1.5E-51 T 23-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 DC74_RS31320 b44d7000d8352b5c7b0249cef68a1cf9 298 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 286 1.1E-37 T 23-04-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 DC74_RS31320 b44d7000d8352b5c7b0249cef68a1cf9 298 PANTHER PTHR22981 1 297 2.9E-118 T 23-04-2016 DC74_RS31320 b44d7000d8352b5c7b0249cef68a1cf9 298 PIRSF PIRSF000103 1 295 2.9E-81 T 23-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 DC74_RS31320 b44d7000d8352b5c7b0249cef68a1cf9 298 PANTHER PTHR22981:SF70 1 297 2.9E-118 T 23-04-2016 DC74_RS17655 0dd8f7e2b5c885cc3d077232671a8fa1 171 Pfam PF04073 Aminoacyl-tRNA editing domain 39 157 2.7E-30 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 DC74_RS17655 0dd8f7e2b5c885cc3d077232671a8fa1 171 PANTHER PTHR30411 20 170 6.7E-41 T 23-04-2016 DC74_RS17655 0dd8f7e2b5c885cc3d077232671a8fa1 171 Gene3D G3DSA:3.90.960.10 20 168 5.0E-45 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 DC74_RS17655 0dd8f7e2b5c885cc3d077232671a8fa1 171 PANTHER PTHR30411:SF1 20 170 6.7E-41 T 23-04-2016 DC74_RS17655 0dd8f7e2b5c885cc3d077232671a8fa1 171 SUPERFAMILY SSF55826 22 167 4.19E-37 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 DC74_RS37330 287a91a0cf0b2f86cf36f60318de4338 438 PANTHER PTHR23501:SF7 1 438 1.4E-109 T 23-04-2016 DC74_RS37330 287a91a0cf0b2f86cf36f60318de4338 438 SUPERFAMILY SSF103473 232 437 2.35E-70 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS37330 287a91a0cf0b2f86cf36f60318de4338 438 SUPERFAMILY SSF103473 2 182 2.35E-70 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS37330 287a91a0cf0b2f86cf36f60318de4338 438 Gene3D G3DSA:1.20.1250.20 247 434 6.2E-27 T 23-04-2016 DC74_RS37330 287a91a0cf0b2f86cf36f60318de4338 438 Pfam PF07690 Major Facilitator Superfamily 4 392 2.9E-55 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS37330 287a91a0cf0b2f86cf36f60318de4338 438 PANTHER PTHR23501 1 438 1.4E-109 T 23-04-2016 DC74_RS37330 287a91a0cf0b2f86cf36f60318de4338 438 Gene3D G3DSA:1.20.1250.20 2 185 3.5E-26 T 23-04-2016 DC74_RS18940 707a84d8129fa17008f87738a493508f 306 PANTHER PTHR13696 8 301 1.1E-18 T 23-04-2016 DC74_RS18940 707a84d8129fa17008f87738a493508f 306 PANTHER PTHR13696:SF1 8 301 1.1E-18 T 23-04-2016 DC74_RS18940 707a84d8129fa17008f87738a493508f 306 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 69 233 4.5E-6 T 23-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DC74_RS18940 707a84d8129fa17008f87738a493508f 306 Gene3D G3DSA:3.40.50.300 66 304 4.2E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18940 707a84d8129fa17008f87738a493508f 306 SUPERFAMILY SSF52540 66 301 1.15E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12880 bcdc576eafe1080775fcf610c07f0e8a 354 SUPERFAMILY SSF47648 17 83 2.49E-20 T 23-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain DC74_RS12880 bcdc576eafe1080775fcf610c07f0e8a 354 SUPERFAMILY SSF52418 87 353 9.94E-83 T 23-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 DC74_RS12880 bcdc576eafe1080775fcf610c07f0e8a 354 Gene3D G3DSA:1.20.970.10 16 80 1.4E-25 T 23-04-2016 DC74_RS12880 bcdc576eafe1080775fcf610c07f0e8a 354 Pfam PF02885 Glycosyl transferase family, helical bundle domain 20 80 2.0E-20 T 23-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain DC74_RS12880 bcdc576eafe1080775fcf610c07f0e8a 354 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 22 350 4.7E-107 T 23-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 DC74_RS12880 bcdc576eafe1080775fcf610c07f0e8a 354 Gene3D G3DSA:3.40.1030.10 86 353 2.4E-102 T 23-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 DC74_RS12880 bcdc576eafe1080775fcf610c07f0e8a 354 PANTHER PTHR11922 10 353 2.6E-95 T 23-04-2016 DC74_RS12880 bcdc576eafe1080775fcf610c07f0e8a 354 Pfam PF00591 Glycosyl transferase family, a/b domain 89 341 1.9E-79 T 23-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 DC74_RS12880 bcdc576eafe1080775fcf610c07f0e8a 354 PANTHER PTHR11922:SF5 10 353 2.6E-95 T 23-04-2016 DC74_RS12880 bcdc576eafe1080775fcf610c07f0e8a 354 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 19 351 35.064 T 23-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 DC74_RS39965 57b14d8929332205fc14839e8131ef44 583 PANTHER PTHR24221:SF161 18 573 1.9E-127 T 23-04-2016 DC74_RS39965 57b14d8929332205fc14839e8131ef44 583 Gene3D G3DSA:1.20.1560.10 20 329 1.5E-43 T 23-04-2016 DC74_RS39965 57b14d8929332205fc14839e8131ef44 583 ProSitePatterns PS00211 ABC transporters family signature. 466 480 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS39965 57b14d8929332205fc14839e8131ef44 583 Gene3D G3DSA:3.40.50.300 384 566 8.4E-37 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39965 57b14d8929332205fc14839e8131ef44 583 PANTHER PTHR24221 18 573 1.9E-127 T 23-04-2016 DC74_RS39965 57b14d8929332205fc14839e8131ef44 583 Pfam PF00005 ABC transporter 385 494 1.8E-9 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS39965 57b14d8929332205fc14839e8131ef44 583 Pfam PF00664 ABC transporter transmembrane region 49 301 5.2E-19 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS39965 57b14d8929332205fc14839e8131ef44 583 SUPERFAMILY SSF90123 19 334 5.89E-50 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS39965 57b14d8929332205fc14839e8131ef44 583 SUPERFAMILY SSF52540 355 562 2.46E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20430 c2c68ade0d6b3d17f32b859d86457375 172 PANTHER PTHR30154 19 167 1.6E-70 T 23-04-2016 DC74_RS20430 c2c68ade0d6b3d17f32b859d86457375 172 SMART SM00344 27 133 1.5E-21 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS20430 c2c68ade0d6b3d17f32b859d86457375 172 Pfam PF01037 Lrp/AsnC ligand binding domain 100 164 1.7E-12 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS20430 c2c68ade0d6b3d17f32b859d86457375 172 Gene3D G3DSA:1.10.10.10 26 78 5.2E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20430 c2c68ade0d6b3d17f32b859d86457375 172 Gene3D G3DSA:3.30.70.920 80 165 6.0E-21 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS20430 c2c68ade0d6b3d17f32b859d86457375 172 SUPERFAMILY SSF46785 27 86 1.36E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20430 c2c68ade0d6b3d17f32b859d86457375 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 43 4.3E-9 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS20430 c2c68ade0d6b3d17f32b859d86457375 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 43 54 4.3E-9 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS20430 c2c68ade0d6b3d17f32b859d86457375 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 54 73 4.3E-9 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS20430 c2c68ade0d6b3d17f32b859d86457375 172 Pfam PF13412 Winged helix-turn-helix DNA-binding 27 74 2.9E-13 T 23-04-2016 DC74_RS20430 c2c68ade0d6b3d17f32b859d86457375 172 PANTHER PTHR30154:SF16 19 167 1.6E-70 T 23-04-2016 DC74_RS20430 c2c68ade0d6b3d17f32b859d86457375 172 SUPERFAMILY SSF54909 90 164 4.83E-14 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS00520 4ea2547bc65c680b8d879c77bc070e33 277 Gene3D G3DSA:3.40.50.1110 51 247 1.3E-11 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS00520 4ea2547bc65c680b8d879c77bc070e33 277 SUPERFAMILY SSF52266 67 250 6.41E-14 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS27225 231fac3d9f5bd617fdbc18eaf626646e 245 SMART SM00448 19 130 1.5E-40 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS27225 231fac3d9f5bd617fdbc18eaf626646e 245 SUPERFAMILY SSF46894 141 240 5.1E-29 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS27225 231fac3d9f5bd617fdbc18eaf626646e 245 Gene3D G3DSA:3.40.50.2300 19 138 2.7E-39 T 23-04-2016 DC74_RS27225 231fac3d9f5bd617fdbc18eaf626646e 245 SMART SM00862 164 239 9.3E-29 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS27225 231fac3d9f5bd617fdbc18eaf626646e 245 PANTHER PTHR26402 19 239 3.6E-89 T 23-04-2016 DC74_RS27225 231fac3d9f5bd617fdbc18eaf626646e 245 PANTHER PTHR26402:SF556 19 239 3.6E-89 T 23-04-2016 DC74_RS27225 231fac3d9f5bd617fdbc18eaf626646e 245 Pfam PF00072 Response regulator receiver domain 21 131 7.6E-29 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS27225 231fac3d9f5bd617fdbc18eaf626646e 245 Gene3D G3DSA:1.10.10.10 141 241 1.4E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27225 231fac3d9f5bd617fdbc18eaf626646e 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 239 8.3E-27 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS27225 231fac3d9f5bd617fdbc18eaf626646e 245 SUPERFAMILY SSF52172 16 139 9.11E-42 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS15965 d30fe0e6c75a2d9fb52e8a659309ceab 302 SMART SM00342 212 295 2.1E-20 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS15965 d30fe0e6c75a2d9fb52e8a659309ceab 302 SUPERFAMILY SSF51215 50 164 1.01E-9 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS15965 d30fe0e6c75a2d9fb52e8a659309ceab 302 SUPERFAMILY SSF46689 252 298 6.72E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS15965 d30fe0e6c75a2d9fb52e8a659309ceab 302 PANTHER PTHR11019:SF137 30 302 3.4E-69 T 23-04-2016 DC74_RS15965 d30fe0e6c75a2d9fb52e8a659309ceab 302 Pfam PF02311 AraC-like ligand binding domain 49 119 2.3E-6 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS15965 d30fe0e6c75a2d9fb52e8a659309ceab 302 Gene3D G3DSA:2.60.120.280 50 171 2.4E-9 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS15965 d30fe0e6c75a2d9fb52e8a659309ceab 302 Pfam PF12833 Helix-turn-helix domain 218 296 1.0E-18 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS15965 d30fe0e6c75a2d9fb52e8a659309ceab 302 Gene3D G3DSA:1.10.10.60 252 296 2.5E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS15965 d30fe0e6c75a2d9fb52e8a659309ceab 302 PANTHER PTHR11019 30 302 3.4E-69 T 23-04-2016 DC74_RS11985 fd496d014a139e0ff573405e9c5f1190 641 SUPERFAMILY SSF53756 77 299 4.71E-9 T 23-04-2016 DC74_RS11985 fd496d014a139e0ff573405e9c5f1190 641 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 82 297 1.7E-10 T 23-04-2016 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 DC74_RS08660 125995be2f1c5a0e4e725c14d554a7fb 185 SUPERFAMILY SSF48498 69 180 5.24E-15 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS08660 125995be2f1c5a0e4e725c14d554a7fb 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 47 1.1E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS08660 125995be2f1c5a0e4e725c14d554a7fb 185 PANTHER PTHR30055 2 183 1.8E-19 T 23-04-2016 DC74_RS08660 125995be2f1c5a0e4e725c14d554a7fb 185 Pfam PF13977 Bacterial transcriptional repressor 70 181 1.3E-21 T 23-04-2016 DC74_RS08660 125995be2f1c5a0e4e725c14d554a7fb 185 Gene3D G3DSA:1.10.357.10 2 182 1.0E-33 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS08660 125995be2f1c5a0e4e725c14d554a7fb 185 SUPERFAMILY SSF46689 2 69 1.03E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 Gene3D G3DSA:2.30.130.10 269 361 4.5E-25 T 23-04-2016 IPR015947 PUA-like domain DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 PRINTS PR00474 Glutamate 5-kinase family signature 114 135 7.4E-53 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 PRINTS PR00474 Glutamate 5-kinase family signature 207 227 7.4E-53 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 PRINTS PR00474 Glutamate 5-kinase family signature 146 173 7.4E-53 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 PRINTS PR00474 Glutamate 5-kinase family signature 40 54 7.4E-53 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 PRINTS PR00474 Glutamate 5-kinase family signature 74 102 7.4E-53 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 Pfam PF00696 Amino acid kinase family 6 233 3.1E-42 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 Gene3D G3DSA:3.40.1160.10 5 251 5.7E-57 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 PIRSF PIRSF000729 1 364 3.0E-121 T 23-04-2016 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 TIGRFAM TIGR01027 proB: glutamate 5-kinase 5 361 1.3E-125 T 23-04-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 SMART SM00359 272 351 1.8E-15 T 23-04-2016 IPR002478 PUA domain GO:0003723 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 Pfam PF01472 PUA domain 272 345 1.1E-17 T 23-04-2016 IPR002478 PUA domain GO:0003723 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 Hamap MF_00456 Glutamate 5-kinase [proB]. 5 253 35.72 T 23-04-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 ProSitePatterns PS00902 Glutamate 5-kinase signature. 205 222 - T 23-04-2016 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 PANTHER PTHR11063:SF6 3 365 6.8E-106 T 23-04-2016 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 SUPERFAMILY SSF53633 5 251 2.75E-62 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 SUPERFAMILY SSF88697 272 362 1.31E-21 T 23-04-2016 IPR015947 PUA-like domain DC74_RS15195 0e2af37a876ab5595bf455f0cf1e51f6 365 PANTHER PTHR11063 3 365 6.8E-106 T 23-04-2016 DC74_RS06145 d56bfa2a9e8b3fda3b9bcac733631f3c 480 Pfam PF07690 Major Facilitator Superfamily 29 422 9.6E-45 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS06145 d56bfa2a9e8b3fda3b9bcac733631f3c 480 PANTHER PTHR23501:SF69 8 476 1.4E-116 T 23-04-2016 DC74_RS06145 d56bfa2a9e8b3fda3b9bcac733631f3c 480 Gene3D G3DSA:1.20.1250.20 13 210 4.3E-28 T 23-04-2016 DC74_RS06145 d56bfa2a9e8b3fda3b9bcac733631f3c 480 Gene3D G3DSA:1.20.1250.20 270 478 4.1E-13 T 23-04-2016 DC74_RS06145 d56bfa2a9e8b3fda3b9bcac733631f3c 480 PANTHER PTHR23501 8 476 1.4E-116 T 23-04-2016 DC74_RS06145 d56bfa2a9e8b3fda3b9bcac733631f3c 480 SUPERFAMILY SSF103473 259 476 2.88E-58 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS06145 d56bfa2a9e8b3fda3b9bcac733631f3c 480 SUPERFAMILY SSF103473 10 207 2.88E-58 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.7E-18 T 23-04-2016 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 5.7E-18 T 23-04-2016 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 5.7E-18 T 23-04-2016 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 260 5.7E-18 T 23-04-2016 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 SUPERFAMILY SSF51905 155 329 2.99E-27 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 PANTHER PTHR22912:SF140 5 451 2.7E-145 T 23-04-2016 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 SUPERFAMILY SSF55424 333 453 1.22E-33 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 340 441 2.9E-21 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 Gene3D G3DSA:3.30.390.30 345 454 6.9E-39 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 183 3.5E-17 T 23-04-2016 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 3.5E-17 T 23-04-2016 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 397 412 3.5E-17 T 23-04-2016 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.5E-17 T 23-04-2016 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 245 259 3.5E-17 T 23-04-2016 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 Gene3D G3DSA:3.50.50.60 122 326 1.9E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 Gene3D G3DSA:3.50.50.60 3 121 5.1E-22 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 317 3.6E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 SUPERFAMILY SSF51905 4 203 1.58E-44 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS29795 d3fbcbc5783f7db15700396ddd4a7abf 466 PANTHER PTHR22912 5 451 2.7E-145 T 23-04-2016 DC74_RS28085 dce7f427c06b05451cc50fd66a60baef 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 23-04-2016 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 DC74_RS28085 dce7f427c06b05451cc50fd66a60baef 112 PRINTS PR00340 P-II protein signature 2 17 2.2E-36 T 23-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 DC74_RS28085 dce7f427c06b05451cc50fd66a60baef 112 PRINTS PR00340 P-II protein signature 52 75 2.2E-36 T 23-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 DC74_RS28085 dce7f427c06b05451cc50fd66a60baef 112 PRINTS PR00340 P-II protein signature 83 103 2.2E-36 T 23-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 DC74_RS28085 dce7f427c06b05451cc50fd66a60baef 112 PRINTS PR00340 P-II protein signature 23 41 2.2E-36 T 23-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 DC74_RS28085 dce7f427c06b05451cc50fd66a60baef 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.4E-39 T 23-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 DC74_RS28085 dce7f427c06b05451cc50fd66a60baef 112 PANTHER PTHR30115 2 112 6.2E-55 T 23-04-2016 DC74_RS28085 dce7f427c06b05451cc50fd66a60baef 112 SUPERFAMILY SSF54913 2 112 4.45E-41 T 23-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta DC74_RS28085 dce7f427c06b05451cc50fd66a60baef 112 Gene3D G3DSA:3.30.70.120 2 112 1.2E-44 T 23-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal DC74_RS28085 dce7f427c06b05451cc50fd66a60baef 112 SMART SM00938 4 105 1.6E-58 T 23-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 DC74_RS18400 a80444dec368ee669b1bf51357cd8931 513 Gene3D G3DSA:3.40.50.980 5 174 5.0E-29 T 23-04-2016 DC74_RS18400 a80444dec368ee669b1bf51357cd8931 513 Pfam PF00501 AMP-binding enzyme 11 403 1.9E-65 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS18400 a80444dec368ee669b1bf51357cd8931 513 Gene3D G3DSA:3.30.300.30 398 499 1.2E-22 T 23-04-2016 DC74_RS18400 a80444dec368ee669b1bf51357cd8931 513 SUPERFAMILY SSF56801 5 502 6.15E-110 T 23-04-2016 DC74_RS18400 a80444dec368ee669b1bf51357cd8931 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 484 9.2E-12 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS18400 a80444dec368ee669b1bf51357cd8931 513 Gene3D G3DSA:2.30.38.10 336 396 1.9E-12 T 23-04-2016 DC74_RS18400 a80444dec368ee669b1bf51357cd8931 513 PANTHER PTHR24096 5 499 1.9E-93 T 23-04-2016 DC74_RS18400 a80444dec368ee669b1bf51357cd8931 513 Gene3D G3DSA:3.40.50.980 175 327 3.0E-21 T 23-04-2016 DC74_RS19250 98542ac9cecd81e8e4ad6deef9f35baf 300 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 15 293 1.4E-89 T 23-04-2016 IPR006371 4-hydroxybenzoate polyprenyltransferase-related DC74_RS19250 98542ac9cecd81e8e4ad6deef9f35baf 300 PANTHER PTHR11048 17 296 2.6E-69 T 23-04-2016 DC74_RS19250 98542ac9cecd81e8e4ad6deef9f35baf 300 Pfam PF01040 UbiA prenyltransferase family 42 279 5.5E-52 T 23-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 DC74_RS19250 98542ac9cecd81e8e4ad6deef9f35baf 300 PANTHER PTHR11048:SF7 17 296 2.6E-69 T 23-04-2016 DC74_RS09850 874841dfb654cfbfee8475c850e76822 393 SUPERFAMILY SSF51695 58 383 7.85E-76 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS09850 874841dfb654cfbfee8475c850e76822 393 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 64 382 2.3E-42 T 23-04-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 DC74_RS09850 874841dfb654cfbfee8475c850e76822 393 PANTHER PTHR23344 59 393 5.7E-96 T 23-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 DC74_RS09850 874841dfb654cfbfee8475c850e76822 393 PANTHER PTHR23344:SF7 59 393 5.7E-96 T 23-04-2016 DC74_RS09850 874841dfb654cfbfee8475c850e76822 393 Gene3D G3DSA:3.20.20.190 59 383 4.6E-86 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS13670 eee684870e8d9819051559791b62695c 421 SUPERFAMILY SSF48239 28 169 1.7E-20 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS13670 eee684870e8d9819051559791b62695c 421 Gene3D G3DSA:1.50.10.20 49 170 3.4E-18 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS13670 eee684870e8d9819051559791b62695c 421 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 120 165 5.6E-9 T 23-04-2016 IPR001330 PFTB repeat GO:0003824 DC74_RS13670 eee684870e8d9819051559791b62695c 421 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 67 114 1.1 T 23-04-2016 IPR001330 PFTB repeat GO:0003824 DC74_RS11835 32fe00f3931c997fa3f8290eb48d8c0e 329 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 4.8E-109 T 23-04-2016 DC74_RS11835 32fe00f3931c997fa3f8290eb48d8c0e 329 Pfam PF02650 WhiA C-terminal HTH domain 221 303 1.6E-19 T 23-04-2016 IPR023054 Sporulation regulator WhiA, C-terminal DC74_RS11835 32fe00f3931c997fa3f8290eb48d8c0e 329 PANTHER PTHR37307 2 322 3.4E-125 T 23-04-2016 DC74_RS11835 32fe00f3931c997fa3f8290eb48d8c0e 329 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.244 T 23-04-2016 IPR003802 Sporulation regulator WhiA GO:0043937 DC74_RS11835 32fe00f3931c997fa3f8290eb48d8c0e 329 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 5.4E-23 T 23-04-2016 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain DC74_RS11835 32fe00f3931c997fa3f8290eb48d8c0e 329 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 5.5E-24 T 23-04-2016 DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 6.7E-5 T 23-04-2016 DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 30 54 6.7E-5 T 23-04-2016 DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 120 140 6.7E-5 T 23-04-2016 DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 28 440 1.8E-73 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 Gene3D G3DSA:1.20.1250.20 284 440 6.9E-21 T 23-04-2016 DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 Gene3D G3DSA:1.20.1250.20 31 212 1.1E-32 T 23-04-2016 DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 Gene3D G3DSA:1.20.1250.20 507 529 6.9E-21 T 23-04-2016 DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 PANTHER PTHR23501:SF73 14 538 5.7E-150 T 23-04-2016 DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 Pfam PF07690 Major Facilitator Superfamily 32 429 7.6E-52 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 SUPERFAMILY SSF103473 29 221 3.14E-66 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 SUPERFAMILY SSF103473 268 439 3.14E-66 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 SUPERFAMILY SSF103473 506 532 3.14E-66 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS02075 ec501fe0e6c5b6e7349cf8d6c623a76b 538 PANTHER PTHR23501 14 538 5.7E-150 T 23-04-2016 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 322 328 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 SUPERFAMILY SSF81665 220 314 3.14E-67 T 23-04-2016 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 SUPERFAMILY SSF81665 610 805 3.14E-67 T 23-04-2016 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 SUPERFAMILY SSF81665 29 122 3.14E-67 T 23-04-2016 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 Gene3D G3DSA:2.70.150.10 117 216 2.0E-22 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 Gene3D G3DSA:2.70.150.10 29 65 2.0E-22 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 Pfam PF00122 E1-E2 ATPase 91 311 2.8E-49 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 Gene3D G3DSA:3.40.1110.10 310 337 1.6E-5 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 Pfam PF00702 haloacid dehalogenase-like hydrolase 316 575 4.5E-19 T 23-04-2016 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 Gene3D G3DSA:1.20.1110.10 530 797 1.1E-53 T 23-04-2016 IPR023298 P-type ATPase, transmembrane domain DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 Gene3D G3DSA:1.20.1110.10 85 116 1.1E-53 T 23-04-2016 IPR023298 P-type ATPase, transmembrane domain DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 534 649 4.4E-27 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 93 339 4.3E-30 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 561 580 6.9E-24 T 23-04-2016 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 169 183 6.9E-24 T 23-04-2016 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 584 596 6.9E-24 T 23-04-2016 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 482 492 6.9E-24 T 23-04-2016 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 320 334 6.9E-24 T 23-04-2016 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 PANTHER PTHR24093:SF298 28 807 0.0 T 23-04-2016 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 592 617 9.3E-8 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 423 441 9.3E-8 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 561 577 9.3E-8 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 Gene3D G3DSA:3.40.1110.10 364 445 7.6E-4 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 SUPERFAMILY SSF56784 318 338 5.06E-39 T 23-04-2016 IPR023214 HAD-like domain DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 SUPERFAMILY SSF56784 420 638 5.06E-39 T 23-04-2016 IPR023214 HAD-like domain DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 PANTHER PTHR24093 28 807 0.0 T 23-04-2016 DC74_RS23760 ec3fe42f2de05cf221451fe18ebbc817 807 SUPERFAMILY SSF81653 124 216 1.44E-19 T 23-04-2016 DC74_RS23090 469cbabd84ee2068627a3a98368c0187 119 PANTHER PTHR33204:SF2 8 104 5.6E-41 T 23-04-2016 DC74_RS23090 469cbabd84ee2068627a3a98368c0187 119 PANTHER PTHR33204 8 104 5.6E-41 T 23-04-2016 DC74_RS23090 469cbabd84ee2068627a3a98368c0187 119 Pfam PF01638 HxlR-like helix-turn-helix 18 105 8.9E-34 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS23090 469cbabd84ee2068627a3a98368c0187 119 SUPERFAMILY SSF46785 7 111 3.41E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23090 469cbabd84ee2068627a3a98368c0187 119 Gene3D G3DSA:1.10.10.10 8 111 7.4E-43 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 SMART SM01260 26 407 2.4E-64 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01950 LanC-like protein superfamily signature 205 221 1.9E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01950 LanC-like protein superfamily signature 138 153 1.9E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01950 LanC-like protein superfamily signature 277 297 1.9E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01950 LanC-like protein superfamily signature 327 340 1.9E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01950 LanC-like protein superfamily signature 29 47 1.9E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01950 LanC-like protein superfamily signature 374 391 1.9E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 Pfam PF05147 Lanthionine synthetase C-like protein 28 407 1.0E-42 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 SUPERFAMILY SSF158745 26 409 8.63E-75 T 23-04-2016 DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01955 Frankia sp. LanC-like protein signature 202 226 7.8E-86 T 23-04-2016 IPR020434 LanC-like protein DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01955 Frankia sp. LanC-like protein signature 137 153 7.8E-86 T 23-04-2016 IPR020434 LanC-like protein DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01955 Frankia sp. LanC-like protein signature 375 392 7.8E-86 T 23-04-2016 IPR020434 LanC-like protein DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01955 Frankia sp. LanC-like protein signature 75 91 7.8E-86 T 23-04-2016 IPR020434 LanC-like protein DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01955 Frankia sp. LanC-like protein signature 277 300 7.8E-86 T 23-04-2016 IPR020434 LanC-like protein DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01955 Frankia sp. LanC-like protein signature 254 268 7.8E-86 T 23-04-2016 IPR020434 LanC-like protein DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01955 Frankia sp. LanC-like protein signature 326 346 7.8E-86 T 23-04-2016 IPR020434 LanC-like protein DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01955 Frankia sp. LanC-like protein signature 226 246 7.8E-86 T 23-04-2016 IPR020434 LanC-like protein DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01955 Frankia sp. LanC-like protein signature 30 45 7.8E-86 T 23-04-2016 IPR020434 LanC-like protein DC74_RS30795 b660745fa1d9a2578c05555d7cfda28d 409 PRINTS PR01955 Frankia sp. LanC-like protein signature 159 175 7.8E-86 T 23-04-2016 IPR020434 LanC-like protein DC74_RS20295 80e4f6847fb52801a363b1aa2bfabce3 297 Gene3D G3DSA:3.90.1720.10 158 262 1.3E-5 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS08550 d810eff85972868643f9389276e547d1 567 SMART SM00710 98 120 5200.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08550 d810eff85972868643f9389276e547d1 567 SMART SM00710 276 298 1600.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08550 d810eff85972868643f9389276e547d1 567 SMART SM00710 299 320 210.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08550 d810eff85972868643f9389276e547d1 567 SMART SM00710 163 185 110.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08550 d810eff85972868643f9389276e547d1 567 SMART SM00710 140 162 1900.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08550 d810eff85972868643f9389276e547d1 567 SMART SM00710 253 275 1.2 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08550 d810eff85972868643f9389276e547d1 567 SMART SM00710 231 252 3600.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS08550 d810eff85972868643f9389276e547d1 567 Gene3D G3DSA:2.160.20.10 221 315 9.9E-9 T 23-04-2016 IPR012334 Pectin lyase fold DC74_RS08550 d810eff85972868643f9389276e547d1 567 Gene3D G3DSA:2.160.20.10 5 200 1.4E-6 T 23-04-2016 IPR012334 Pectin lyase fold DC74_RS08550 d810eff85972868643f9389276e547d1 567 Gene3D G3DSA:2.160.20.10 360 474 9.9E-9 T 23-04-2016 IPR012334 Pectin lyase fold DC74_RS08550 d810eff85972868643f9389276e547d1 567 Pfam PF13229 Right handed beta helix region 247 396 8.0E-11 T 23-04-2016 DC74_RS08550 d810eff85972868643f9389276e547d1 567 SUPERFAMILY SSF51126 4 220 5.11E-15 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS08550 d810eff85972868643f9389276e547d1 567 SUPERFAMILY SSF51126 382 478 1.42E-13 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS08550 d810eff85972868643f9389276e547d1 567 SUPERFAMILY SSF51126 179 323 1.42E-13 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS08550 d810eff85972868643f9389276e547d1 567 PANTHER PTHR22990 114 357 6.9E-23 T 23-04-2016 DC74_RS09300 b22dc885270db25ad488aa2606a9e4c5 304 PANTHER PTHR30118:SF5 1 296 1.9E-101 T 23-04-2016 DC74_RS09300 b22dc885270db25ad488aa2606a9e4c5 304 Pfam PF03466 LysR substrate binding domain 97 299 5.4E-25 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS09300 b22dc885270db25ad488aa2606a9e4c5 304 Gene3D G3DSA:3.40.190.10 274 299 6.4E-24 T 23-04-2016 DC74_RS09300 b22dc885270db25ad488aa2606a9e4c5 304 Gene3D G3DSA:3.40.190.10 93 173 6.4E-24 T 23-04-2016 DC74_RS09300 b22dc885270db25ad488aa2606a9e4c5 304 Gene3D G3DSA:1.10.10.10 5 87 5.3E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09300 b22dc885270db25ad488aa2606a9e4c5 304 SUPERFAMILY SSF46785 7 85 9.37E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09300 b22dc885270db25ad488aa2606a9e4c5 304 SUPERFAMILY SSF53850 93 297 1.99E-42 T 23-04-2016 DC74_RS09300 b22dc885270db25ad488aa2606a9e4c5 304 Gene3D G3DSA:3.40.190.10 174 270 9.7E-30 T 23-04-2016 DC74_RS09300 b22dc885270db25ad488aa2606a9e4c5 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 6.1E-15 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS09300 b22dc885270db25ad488aa2606a9e4c5 304 PANTHER PTHR30118 1 296 1.9E-101 T 23-04-2016 DC74_RS06265 aec8759cde5bd19f8dc1eb2790c48fb7 279 PANTHER PTHR11908 23 170 1.8E-25 T 23-04-2016 DC74_RS06265 aec8759cde5bd19f8dc1eb2790c48fb7 279 Gene3D G3DSA:3.30.465.10 57 171 4.5E-21 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS06265 aec8759cde5bd19f8dc1eb2790c48fb7 279 SUPERFAMILY SSF56176 16 171 9.27E-28 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS06265 aec8759cde5bd19f8dc1eb2790c48fb7 279 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 22 171 1.5E-14 T 23-04-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DC74_RS06265 aec8759cde5bd19f8dc1eb2790c48fb7 279 PANTHER PTHR11908:SF68 23 170 1.8E-25 T 23-04-2016 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 PRINTS PR00359 B-class P450 signature 388 397 7.1E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 PRINTS PR00359 B-class P450 signature 397 408 7.1E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 PRINTS PR00359 B-class P450 signature 339 366 7.1E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 PRINTS PR00359 B-class P450 signature 235 257 7.1E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 PRINTS PR00359 B-class P450 signature 321 332 7.1E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 PRINTS PR00359 B-class P450 signature 180 196 7.1E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 PRINTS PR00359 B-class P450 signature 128 139 7.1E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 PRINTS PR00359 B-class P450 signature 367 382 7.1E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 PRINTS PR00359 B-class P450 signature 197 212 7.1E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 Pfam PF00067 Cytochrome P450 230 417 4.2E-20 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 PANTHER PTHR11712 4 451 4.4E-133 T 23-04-2016 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 SUPERFAMILY SSF48264 43 450 9.43E-103 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS17375 708a7adfe1474004d1fefff3022ac3ab 459 Gene3D G3DSA:1.10.630.10 28 451 3.5E-134 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS22920 55de165bdb87480217d0fbfc32af89a9 286 SUPERFAMILY SSF89392 105 268 5.89E-10 T 23-04-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX DC74_RS14230 01785af1e3f9be2787dd6d7ccdfcc06b 332 SUPERFAMILY SSF53335 162 288 2.9E-19 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14230 01785af1e3f9be2787dd6d7ccdfcc06b 332 Gene3D G3DSA:3.40.50.150 187 290 4.2E-11 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14230 01785af1e3f9be2787dd6d7ccdfcc06b 332 Pfam PF02384 N-6 DNA Methylase 189 290 2.6E-11 T 23-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 DC74_RS14230 01785af1e3f9be2787dd6d7ccdfcc06b 332 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 195 211 7.3E-5 T 23-04-2016 DC74_RS14230 01785af1e3f9be2787dd6d7ccdfcc06b 332 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 223 237 7.3E-5 T 23-04-2016 DC74_RS24890 2816b485f835f046a2c8001ef44ccacd 325 Gene3D G3DSA:3.90.550.10 3 203 7.6E-46 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS24890 2816b485f835f046a2c8001ef44ccacd 325 PANTHER PTHR22916 2 317 1.0E-53 T 23-04-2016 DC74_RS24890 2816b485f835f046a2c8001ef44ccacd 325 PANTHER PTHR22916:SF23 2 317 1.0E-53 T 23-04-2016 DC74_RS24890 2816b485f835f046a2c8001ef44ccacd 325 Pfam PF00535 Glycosyl transferase family 2 5 115 6.5E-34 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS24890 2816b485f835f046a2c8001ef44ccacd 325 SUPERFAMILY SSF53448 3 231 8.34E-47 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS24730 e1bc4ce2bc2aadfdb440399d9f5c1914 478 SUPERFAMILY SSF46785 21 99 2.18E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24730 e1bc4ce2bc2aadfdb440399d9f5c1914 478 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 2.2E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS24730 e1bc4ce2bc2aadfdb440399d9f5c1914 478 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 2.2E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS24730 e1bc4ce2bc2aadfdb440399d9f5c1914 478 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 89 5.7E-16 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS24730 e1bc4ce2bc2aadfdb440399d9f5c1914 478 SMART SM00345 30 89 2.2E-14 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS24730 e1bc4ce2bc2aadfdb440399d9f5c1914 478 Gene3D G3DSA:1.10.10.10 29 91 3.1E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS40570 35ae8ccea6d117175852212eb8094917 431 SUPERFAMILY SSF47090 198 260 1.65E-7 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS40570 35ae8ccea6d117175852212eb8094917 431 Gene3D G3DSA:1.10.530.10 330 409 3.1E-4 T 23-04-2016 DC74_RS40570 35ae8ccea6d117175852212eb8094917 431 Gene3D G3DSA:1.10.101.10 198 260 3.6E-10 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS40570 35ae8ccea6d117175852212eb8094917 431 SUPERFAMILY SSF53955 328 413 3.09E-7 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS40570 35ae8ccea6d117175852212eb8094917 431 Pfam PF01471 Putative peptidoglycan binding domain 203 254 3.2E-5 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS29040 906697116137695b98babad7bf70a891 336 Pfam PF06999 Sucrase/ferredoxin-like 15 213 3.6E-19 T 23-04-2016 IPR009737 Thioredoxin-like ferredoxin DC74_RS29040 906697116137695b98babad7bf70a891 336 Gene3D G3DSA:3.40.30.10 129 216 6.2E-10 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS29040 906697116137695b98babad7bf70a891 336 SUPERFAMILY SSF52833 128 217 3.35E-11 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS29040 906697116137695b98babad7bf70a891 336 PANTHER PTHR31902:SF6 4 242 3.6E-67 T 23-04-2016 DC74_RS29040 906697116137695b98babad7bf70a891 336 PIRSF PIRSF035042 1 323 3.2E-56 T 23-04-2016 IPR010350 Thioredoxin-like ferredoxin, bacteria DC74_RS29040 906697116137695b98babad7bf70a891 336 PANTHER PTHR31902:SF6 264 311 3.6E-67 T 23-04-2016 DC74_RS29040 906697116137695b98babad7bf70a891 336 PANTHER PTHR31902 4 242 3.6E-67 T 23-04-2016 DC74_RS29040 906697116137695b98babad7bf70a891 336 PANTHER PTHR31902 264 311 3.6E-67 T 23-04-2016 DC74_RS17985 cb458e220bf4897a75ae82d2f7b6bac9 256 SUPERFAMILY SSF100950 76 240 1.26E-24 T 23-04-2016 DC74_RS17985 cb458e220bf4897a75ae82d2f7b6bac9 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.7E-9 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS17985 cb458e220bf4897a75ae82d2f7b6bac9 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.7E-9 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS17985 cb458e220bf4897a75ae82d2f7b6bac9 256 SMART SM00420 6 58 1.2E-12 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS17985 cb458e220bf4897a75ae82d2f7b6bac9 256 Gene3D G3DSA:3.40.50.1360 80 219 4.7E-7 T 23-04-2016 DC74_RS17985 cb458e220bf4897a75ae82d2f7b6bac9 256 Pfam PF00455 DeoR C terminal sensor domain 76 236 3.1E-49 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain DC74_RS17985 cb458e220bf4897a75ae82d2f7b6bac9 256 SUPERFAMILY SSF46785 5 58 4.18E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17985 cb458e220bf4897a75ae82d2f7b6bac9 256 PANTHER PTHR30363 1 256 3.1E-93 T 23-04-2016 DC74_RS17985 cb458e220bf4897a75ae82d2f7b6bac9 256 Gene3D G3DSA:1.10.10.10 5 79 1.2E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17985 cb458e220bf4897a75ae82d2f7b6bac9 256 SMART SM01134 73 237 1.1E-66 T 23-04-2016 DC74_RS17985 cb458e220bf4897a75ae82d2f7b6bac9 256 Pfam PF08220 DeoR-like helix-turn-helix domain 6 56 1.3E-14 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS17985 cb458e220bf4897a75ae82d2f7b6bac9 256 PANTHER PTHR30363:SF1 1 256 3.1E-93 T 23-04-2016 DC74_RS02620 b0ea2b803c9b66348375d9825a4ef702 307 Pfam PF00296 Luciferase-like monooxygenase 14 280 9.8E-42 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS02620 b0ea2b803c9b66348375d9825a4ef702 307 PANTHER PTHR30011 20 295 1.2E-24 T 23-04-2016 DC74_RS02620 b0ea2b803c9b66348375d9825a4ef702 307 SUPERFAMILY SSF51679 1 305 6.02E-52 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS02620 b0ea2b803c9b66348375d9825a4ef702 307 TIGRFAM TIGR03564 F420_MSMEG_4879: F420-dependent oxidoreductase, MSMEG_4879 family 20 283 1.2E-108 T 23-04-2016 IPR019910 Luciferase-like, F420-dependent oxidoreductase, MSMEG4879, predicted DC74_RS02620 b0ea2b803c9b66348375d9825a4ef702 307 Gene3D G3DSA:3.20.20.30 1 304 1.6E-49 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS11390 1f33f99ee4c8a21b5eff88876185ce58 421 PANTHER PTHR21240 104 375 7.5E-25 T 23-04-2016 DC74_RS11390 1f33f99ee4c8a21b5eff88876185ce58 421 Gene3D G3DSA:3.20.20.140 6 372 1.1E-54 T 23-04-2016 DC74_RS11390 1f33f99ee4c8a21b5eff88876185ce58 421 SUPERFAMILY SSF51556 60 366 1.98E-59 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS11390 1f33f99ee4c8a21b5eff88876185ce58 421 SUPERFAMILY SSF51556 2 29 1.98E-59 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS11390 1f33f99ee4c8a21b5eff88876185ce58 421 Pfam PF04909 Amidohydrolase 6 365 1.1E-23 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS28225 dea2538e13622f5e358ac38e5ff43e9a 554 PANTHER PTHR30183:SF8 2 553 5.6E-189 T 23-04-2016 DC74_RS28225 dea2538e13622f5e358ac38e5ff43e9a 554 Gene3D G3DSA:1.10.3720.10 272 544 8.1E-41 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28225 dea2538e13622f5e358ac38e5ff43e9a 554 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 257 1.5E-12 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28225 dea2538e13622f5e358ac38e5ff43e9a 554 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 409 537 7.3E-10 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28225 dea2538e13622f5e358ac38e5ff43e9a 554 SUPERFAMILY SSF161098 4 258 6.15E-53 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28225 dea2538e13622f5e358ac38e5ff43e9a 554 PANTHER PTHR30183 2 553 5.6E-189 T 23-04-2016 DC74_RS28225 dea2538e13622f5e358ac38e5ff43e9a 554 Gene3D G3DSA:1.10.3720.10 6 259 1.7E-48 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28225 dea2538e13622f5e358ac38e5ff43e9a 554 SUPERFAMILY SSF161098 279 548 1.7E-44 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16315 4e39e2682cdc62457be5a88303204ff2 513 SUPERFAMILY SSF103473 36 488 4.05E-76 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS16315 4e39e2682cdc62457be5a88303204ff2 513 Gene3D G3DSA:1.20.1250.20 52 257 9.5E-28 T 23-04-2016 DC74_RS16315 4e39e2682cdc62457be5a88303204ff2 513 Gene3D G3DSA:1.20.1250.20 297 485 6.6E-24 T 23-04-2016 DC74_RS16315 4e39e2682cdc62457be5a88303204ff2 513 PANTHER PTHR23508 3 503 5.7E-256 T 23-04-2016 DC74_RS16315 4e39e2682cdc62457be5a88303204ff2 513 Pfam PF00083 Sugar (and other) transporter 57 489 3.5E-47 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS16315 4e39e2682cdc62457be5a88303204ff2 513 ProSitePatterns PS00217 Sugar transport proteins signature 2. 164 189 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS16315 4e39e2682cdc62457be5a88303204ff2 513 PANTHER PTHR23508:SF17 3 503 5.7E-256 T 23-04-2016 DC74_RS25560 a9e505842b43c83ad6099c6845ae1b77 831 SUPERFAMILY SSF55874 739 823 1.13E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS25560 a9e505842b43c83ad6099c6845ae1b77 831 SUPERFAMILY SSF55781 405 463 1.33E-6 T 23-04-2016 IPR029016 GAF domain-like DC74_RS25560 a9e505842b43c83ad6099c6845ae1b77 831 SMART SM00331 483 699 7.6E-37 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS25560 a9e505842b43c83ad6099c6845ae1b77 831 PANTHER PTHR21021 436 708 7.8E-61 T 23-04-2016 DC74_RS25560 a9e505842b43c83ad6099c6845ae1b77 831 SUPERFAMILY SSF81606 497 700 7.06E-9 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS25560 a9e505842b43c83ad6099c6845ae1b77 831 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 509 700 2.6E-53 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS25560 a9e505842b43c83ad6099c6845ae1b77 831 Gene3D G3DSA:3.30.450.40 272 459 2.5E-24 T 23-04-2016 IPR029016 GAF domain-like DC74_RS25560 a9e505842b43c83ad6099c6845ae1b77 831 PANTHER PTHR21021:SF19 436 708 7.8E-61 T 23-04-2016 DC74_RS25560 a9e505842b43c83ad6099c6845ae1b77 831 Pfam PF13581 Histidine kinase-like ATPase domain 718 805 3.3E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28260 4c0ecdf6beeb92a443f9c39bffbd44d9 140 Pfam PF01042 Endoribonuclease L-PSP 31 138 7.8E-27 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS28260 4c0ecdf6beeb92a443f9c39bffbd44d9 140 Gene3D G3DSA:3.30.1330.40 15 138 7.8E-40 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS28260 4c0ecdf6beeb92a443f9c39bffbd44d9 140 SUPERFAMILY SSF55298 16 138 9.74E-34 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS28260 4c0ecdf6beeb92a443f9c39bffbd44d9 140 PANTHER PTHR11803 15 139 5.9E-34 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS13870 b1842e4370cb57230950206416a94b0f 205 Pfam PF00583 Acetyltransferase (GNAT) family 68 162 5.4E-9 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS13870 b1842e4370cb57230950206416a94b0f 205 Gene3D G3DSA:3.40.630.30 27 173 1.6E-16 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS13870 b1842e4370cb57230950206416a94b0f 205 SUPERFAMILY SSF55729 27 172 4.96E-16 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.8E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.8E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.8E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 Gene3D G3DSA:3.40.50.720 5 247 1.1E-81 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 PANTHER PTHR24321 6 247 2.8E-47 T 23-04-2016 DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 PANTHER PTHR24321:SF6 6 247 2.8E-47 T 23-04-2016 DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 SUPERFAMILY SSF51735 7 247 2.43E-77 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 187 3.0E-4 T 23-04-2016 DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.5E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.5E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.5E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.5E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.5E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.5E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11555 87a7b17eb8cf9db0f35a89d05dcf595f 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 6.2E-61 T 23-04-2016 DC74_RS11625 1a572e616ed884d075256588dc0afcda 256 SUPERFAMILY SSF46785 11 83 3.3E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11625 1a572e616ed884d075256588dc0afcda 256 SUPERFAMILY SSF55781 78 251 1.96E-45 T 23-04-2016 IPR029016 GAF domain-like DC74_RS11625 1a572e616ed884d075256588dc0afcda 256 PANTHER PTHR30136 6 252 4.0E-141 T 23-04-2016 DC74_RS11625 1a572e616ed884d075256588dc0afcda 256 SMART SM00346 11 101 5.7E-19 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS11625 1a572e616ed884d075256588dc0afcda 256 Pfam PF09339 IclR helix-turn-helix domain 13 63 1.8E-12 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS11625 1a572e616ed884d075256588dc0afcda 256 Gene3D G3DSA:1.10.10.10 10 74 9.3E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11625 1a572e616ed884d075256588dc0afcda 256 Pfam PF01614 Bacterial transcriptional regulator 133 245 6.8E-27 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS11625 1a572e616ed884d075256588dc0afcda 256 PANTHER PTHR30136:SF12 6 252 4.0E-141 T 23-04-2016 DC74_RS11625 1a572e616ed884d075256588dc0afcda 256 Gene3D G3DSA:3.30.450.40 86 250 1.7E-50 T 23-04-2016 IPR029016 GAF domain-like DC74_RS34230 d303098589f950814acdd7ab8d0766f5 377 SUPERFAMILY SSF54631 244 367 7.33E-13 T 23-04-2016 DC74_RS34230 d303098589f950814acdd7ab8d0766f5 377 PANTHER PTHR39188 7 329 1.0E-13 T 23-04-2016 DC74_RS34230 d303098589f950814acdd7ab8d0766f5 377 PIRSF PIRSF006404 1 374 9.9E-79 T 23-04-2016 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS DC74_RS34230 d303098589f950814acdd7ab8d0766f5 377 Pfam PF00571 CBS domain 310 361 9.2E-5 T 23-04-2016 IPR000644 CBS domain DC74_RS34230 d303098589f950814acdd7ab8d0766f5 377 Pfam PF02163 Peptidase family M50 141 179 1.3E-8 T 23-04-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 DC74_RS34230 d303098589f950814acdd7ab8d0766f5 377 Gene3D G3DSA:3.10.580.10 245 365 2.3E-11 T 23-04-2016 DC74_RS32340 a7a0dd76d389e8836635bee0d6b06816 196 Gene3D G3DSA:3.40.50.360 8 187 1.4E-49 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS32340 a7a0dd76d389e8836635bee0d6b06816 196 SUPERFAMILY SSF52218 8 173 3.02E-39 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS32340 a7a0dd76d389e8836635bee0d6b06816 196 PANTHER PTHR30543:SF1 3 194 2.2E-52 T 23-04-2016 DC74_RS32340 a7a0dd76d389e8836635bee0d6b06816 196 PANTHER PTHR30543 3 194 2.2E-52 T 23-04-2016 DC74_RS32340 a7a0dd76d389e8836635bee0d6b06816 196 Pfam PF03358 NADPH-dependent FMN reductase 8 149 1.6E-37 T 23-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00385 P450 superfamily signature 241 258 5.0E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00385 P450 superfamily signature 343 352 5.0E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00385 P450 superfamily signature 352 363 5.0E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00385 P450 superfamily signature 276 287 5.0E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PANTHER PTHR24286:SF42 78 400 2.0E-90 T 23-04-2016 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PANTHER PTHR24286 78 400 2.0E-90 T 23-04-2016 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00359 B-class P450 signature 322 337 8.1E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00359 B-class P450 signature 132 148 8.1E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00359 B-class P450 signature 276 287 8.1E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00359 B-class P450 signature 343 352 8.1E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00359 B-class P450 signature 294 321 8.1E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00359 B-class P450 signature 195 217 8.1E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00359 B-class P450 signature 352 363 8.1E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00359 B-class P450 signature 149 164 8.1E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 PRINTS PR00359 B-class P450 signature 82 93 8.1E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 Pfam PF00067 Cytochrome P450 187 386 1.8E-28 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 SUPERFAMILY SSF48264 15 400 2.62E-88 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03970 f2912bbc206a5406c5e43e71c660b4d5 409 Gene3D G3DSA:1.10.630.10 15 400 3.6E-114 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS10690 98048e7636670f6c0c1e6a5a70735aa0 153 Gene3D G3DSA:3.10.129.10 11 149 8.6E-38 T 23-04-2016 IPR029069 HotDog domain DC74_RS10690 98048e7636670f6c0c1e6a5a70735aa0 153 Pfam PF01575 MaoC like domain 15 132 4.4E-26 T 23-04-2016 IPR002539 MaoC-like domain DC74_RS10690 98048e7636670f6c0c1e6a5a70735aa0 153 PANTHER PTHR13078 4 148 9.1E-41 T 23-04-2016 DC74_RS10690 98048e7636670f6c0c1e6a5a70735aa0 153 SUPERFAMILY SSF54637 11 149 3.83E-38 T 23-04-2016 IPR029069 HotDog domain DC74_RS38265 0eeb2d44afd96deda52505f745d175a1 429 Gene3D G3DSA:3.90.1150.10 7 166 7.5E-39 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS38265 0eeb2d44afd96deda52505f745d175a1 429 Gene3D G3DSA:3.90.1150.10 251 422 3.9E-56 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS38265 0eeb2d44afd96deda52505f745d175a1 429 PANTHER PTHR11751 56 414 5.4E-68 T 23-04-2016 DC74_RS38265 0eeb2d44afd96deda52505f745d175a1 429 SUPERFAMILY SSF53383 61 410 1.52E-49 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS38265 0eeb2d44afd96deda52505f745d175a1 429 Pfam PF12897 Alanine-glyoxylate amino-transferase 8 422 5.8E-179 T 23-04-2016 IPR024551 Aminotransferase, putative DC74_RS38265 0eeb2d44afd96deda52505f745d175a1 429 PANTHER PTHR11751:SF110 56 414 5.4E-68 T 23-04-2016 DC74_RS36885 8f5cf3a5d286017ced4e17ae43ee68db 275 SMART SM00382 47 233 1.2E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS36885 8f5cf3a5d286017ced4e17ae43ee68db 275 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS36885 8f5cf3a5d286017ced4e17ae43ee68db 275 Gene3D G3DSA:3.40.50.300 23 246 7.7E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36885 8f5cf3a5d286017ced4e17ae43ee68db 275 SUPERFAMILY SSF52540 16 245 1.09E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS36885 8f5cf3a5d286017ced4e17ae43ee68db 275 Pfam PF00005 ABC transporter 39 185 1.3E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS36885 8f5cf3a5d286017ced4e17ae43ee68db 275 PANTHER PTHR24220 24 272 5.3E-91 T 23-04-2016 DC74_RS36885 8f5cf3a5d286017ced4e17ae43ee68db 275 PANTHER PTHR24220:SF558 24 272 5.3E-91 T 23-04-2016 DC74_RS08405 e29c807d0727f8da4ed448a3c40f3c1e 232 Gene3D G3DSA:3.40.50.1820 146 229 6.3E-17 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08405 e29c807d0727f8da4ed448a3c40f3c1e 232 Gene3D G3DSA:3.40.50.1820 5 145 5.9E-42 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08405 e29c807d0727f8da4ed448a3c40f3c1e 232 SUPERFAMILY SSF53474 5 229 3.19E-58 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08405 e29c807d0727f8da4ed448a3c40f3c1e 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 5.1E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS08405 e29c807d0727f8da4ed448a3c40f3c1e 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 5.1E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS08405 e29c807d0727f8da4ed448a3c40f3c1e 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 5.1E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS08405 e29c807d0727f8da4ed448a3c40f3c1e 232 PANTHER PTHR10992 5 230 1.4E-51 T 23-04-2016 DC74_RS08405 e29c807d0727f8da4ed448a3c40f3c1e 232 Pfam PF12697 Alpha/beta hydrolase family 28 222 5.0E-18 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 SUPERFAMILY SSF48264 7 388 5.37E-90 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PANTHER PTHR24286:SF42 22 388 7.3E-91 T 23-04-2016 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 Pfam PF00067 Cytochrome P450 261 355 3.1E-17 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PANTHER PTHR24286 22 388 7.3E-91 T 23-04-2016 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00385 P450 superfamily signature 337 348 4.8E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00385 P450 superfamily signature 261 272 4.8E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00385 P450 superfamily signature 224 241 4.8E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00385 P450 superfamily signature 328 337 4.8E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00359 B-class P450 signature 307 322 8.9E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00359 B-class P450 signature 279 306 8.9E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00359 B-class P450 signature 78 89 8.9E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00359 B-class P450 signature 328 337 8.9E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00359 B-class P450 signature 261 272 8.9E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00359 B-class P450 signature 179 201 8.9E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00359 B-class P450 signature 337 348 8.9E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00359 B-class P450 signature 142 157 8.9E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 PRINTS PR00359 B-class P450 signature 125 141 8.9E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 330 339 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS02275 92f3802b978e2beb2a4a7c684e441f97 388 Gene3D G3DSA:1.10.630.10 5 388 2.6E-119 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 3 475 49.977 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 Gene3D G3DSA:3.40.50.1480 7 242 2.4E-149 T 23-04-2016 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 Gene3D G3DSA:3.40.50.1480 404 483 2.4E-149 T 23-04-2016 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 Gene3D G3DSA:3.40.50.720 243 402 2.0E-51 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 SUPERFAMILY SSF52283 5 155 9.64E-116 T 23-04-2016 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 SUPERFAMILY SSF52283 404 483 9.64E-116 T 23-04-2016 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 SUPERFAMILY SSF52283 193 240 9.64E-116 T 23-04-2016 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 8 475 2.4E-192 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 263 279 - T 23-04-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 SMART SM00996 7 482 0.0 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 SUPERFAMILY SSF51735 241 403 1.54E-77 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 SMART SM00997 241 403 3.6E-110 T 23-04-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 PIRSF PIRSF001109 1 483 2.5E-195 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 241 403 5.0E-83 T 23-04-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 8 482 1.9E-149 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 79 93 - T 23-04-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 PANTHER PTHR23420:SF6 191 483 0.0 T 23-04-2016 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 PANTHER PTHR23420:SF6 8 153 0.0 T 23-04-2016 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 PANTHER PTHR23420 191 483 0.0 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS37245 bd08b2768d4082ae1a41e466828a7762 483 PANTHER PTHR23420 8 153 0.0 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 11 127 9.5E-37 T 23-04-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 40 62 4.4E-47 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 258 276 4.4E-47 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 116 137 4.4E-47 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 161 181 4.4E-47 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 81 108 4.4E-47 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 241 257 4.4E-47 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 Gene3D G3DSA:3.40.192.10 13 145 5.0E-39 T 23-04-2016 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 SUPERFAMILY SSF53223 9 128 8.92E-35 T 23-04-2016 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 134 284 3.2E-58 T 23-04-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 SUPERFAMILY SSF51735 139 284 4.17E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07010 cef36685f43182e87ef75219a173e531 289 Gene3D G3DSA:3.40.50.720 146 266 6.4E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07010 cef36685f43182e87ef75219a173e531 289 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 262 270 - T 23-04-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 PANTHER PTHR10025 1 281 5.8E-124 T 23-04-2016 DC74_RS07010 cef36685f43182e87ef75219a173e531 289 Hamap MF_01576 Bifunctional protein FolD [folD]. 9 285 34.47 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS07870 98741423d6f918bfa6bed3372cd89e7e 272 Gene3D G3DSA:1.10.357.10 115 257 9.6E-38 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS07870 98741423d6f918bfa6bed3372cd89e7e 272 Gene3D G3DSA:1.10.357.10 3 77 9.6E-38 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS07870 98741423d6f918bfa6bed3372cd89e7e 272 PANTHER PTHR30328 8 90 5.7E-13 T 23-04-2016 DC74_RS07870 98741423d6f918bfa6bed3372cd89e7e 272 SUPERFAMILY SSF46689 8 73 1.06E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07870 98741423d6f918bfa6bed3372cd89e7e 272 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 8.7E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS07870 98741423d6f918bfa6bed3372cd89e7e 272 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 8.7E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS07870 98741423d6f918bfa6bed3372cd89e7e 272 SUPERFAMILY SSF48498 126 258 4.23E-29 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS07870 98741423d6f918bfa6bed3372cd89e7e 272 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 7.2E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS07870 98741423d6f918bfa6bed3372cd89e7e 272 PANTHER PTHR30328:SF8 8 90 5.7E-13 T 23-04-2016 DC74_RS39800 305d6acace4f996fd564d610e6def437 138 Pfam PF00293 NUDIX domain 8 126 5.4E-18 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS39800 305d6acace4f996fd564d610e6def437 138 PRINTS PR00502 NUDIX hydrolase family signature 52 67 1.0E-7 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS39800 305d6acace4f996fd564d610e6def437 138 PRINTS PR00502 NUDIX hydrolase family signature 38 52 1.0E-7 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS39800 305d6acace4f996fd564d610e6def437 138 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS39800 305d6acace4f996fd564d610e6def437 138 SUPERFAMILY SSF55811 7 136 4.33E-28 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS39800 305d6acace4f996fd564d610e6def437 138 Gene3D G3DSA:3.90.79.10 6 132 3.0E-28 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS39800 305d6acace4f996fd564d610e6def437 138 PANTHER PTHR22769 8 138 1.9E-17 T 23-04-2016 DC74_RS20995 c4e413bcc3e1aa387a537ce1600fafb6 366 SUPERFAMILY SSF47413 19 77 2.95E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS20995 c4e413bcc3e1aa387a537ce1600fafb6 366 PANTHER PTHR30146 19 361 3.5E-196 T 23-04-2016 DC74_RS20995 c4e413bcc3e1aa387a537ce1600fafb6 366 PANTHER PTHR30146:SF47 19 361 3.5E-196 T 23-04-2016 DC74_RS20995 c4e413bcc3e1aa387a537ce1600fafb6 366 Pfam PF00356 Bacterial regulatory proteins, lacI family 22 66 7.4E-14 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS20995 c4e413bcc3e1aa387a537ce1600fafb6 366 SUPERFAMILY SSF53822 98 350 7.4E-36 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS20995 c4e413bcc3e1aa387a537ce1600fafb6 366 Pfam PF13377 Periplasmic binding protein-like domain 189 348 3.9E-27 T 23-04-2016 DC74_RS20995 c4e413bcc3e1aa387a537ce1600fafb6 366 Gene3D G3DSA:3.40.50.2300 76 186 2.6E-9 T 23-04-2016 DC74_RS20995 c4e413bcc3e1aa387a537ce1600fafb6 366 Gene3D G3DSA:3.40.50.2300 187 349 2.4E-33 T 23-04-2016 DC74_RS20995 c4e413bcc3e1aa387a537ce1600fafb6 366 Gene3D G3DSA:1.10.260.40 21 75 3.1E-23 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS20995 c4e413bcc3e1aa387a537ce1600fafb6 366 ProSitePatterns PS00356 LacI-type HTH domain signature. 22 40 - T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS20995 c4e413bcc3e1aa387a537ce1600fafb6 366 SMART SM00354 19 89 9.9E-21 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS32095 22da4212efaeeb51873b5346f67e9a0c 509 Gene3D G3DSA:3.40.309.10 264 456 2.8E-33 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS32095 22da4212efaeeb51873b5346f67e9a0c 509 Pfam PF00171 Aldehyde dehydrogenase family 44 485 1.4E-93 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS32095 22da4212efaeeb51873b5346f67e9a0c 509 PANTHER PTHR11699 12 481 5.8E-157 T 23-04-2016 DC74_RS32095 22da4212efaeeb51873b5346f67e9a0c 509 SUPERFAMILY SSF53720 28 486 2.49E-76 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS32095 22da4212efaeeb51873b5346f67e9a0c 509 PANTHER PTHR11699:SF198 12 481 5.8E-157 T 23-04-2016 DC74_RS32095 22da4212efaeeb51873b5346f67e9a0c 509 Gene3D G3DSA:3.40.605.10 29 263 3.8E-38 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS04345 46fb54334453fac1342124fc4ef8e909 184 PANTHER PTHR33164 22 169 2.9E-21 T 23-04-2016 DC74_RS04345 46fb54334453fac1342124fc4ef8e909 184 SMART SM00347 45 145 6.0E-15 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS04345 46fb54334453fac1342124fc4ef8e909 184 Gene3D G3DSA:1.10.10.10 21 158 5.7E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04345 46fb54334453fac1342124fc4ef8e909 184 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 5.8E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS04345 46fb54334453fac1342124fc4ef8e909 184 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 5.8E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS04345 46fb54334453fac1342124fc4ef8e909 184 PRINTS PR00598 Bacterial regulatory protein MarR family signature 135 155 5.8E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS04345 46fb54334453fac1342124fc4ef8e909 184 SUPERFAMILY SSF46785 30 157 1.22E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04345 46fb54334453fac1342124fc4ef8e909 184 Pfam PF12802 MarR family 57 109 2.0E-11 T 23-04-2016 DC74_RS04345 46fb54334453fac1342124fc4ef8e909 184 ProSitePatterns PS01117 MarR-type HTH domain signature. 84 118 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 PANTHER PTHR11530 14 341 6.5E-111 T 23-04-2016 IPR023209 D-amino-acid oxidase GO:0003884|GO:0046416|GO:0071949 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 Pfam PF01266 FAD dependent oxidoreductase 17 332 4.9E-37 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 PIRSF PIRSF000189 13 347 5.9E-78 T 23-04-2016 IPR023209 D-amino-acid oxidase GO:0003884|GO:0046416|GO:0071949 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 PANTHER PTHR11530:SF10 14 341 6.5E-111 T 23-04-2016 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 SUPERFAMILY SSF54373 206 296 7.46E-17 T 23-04-2016 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 Gene3D G3DSA:3.50.50.60 296 338 1.2E-15 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 Gene3D G3DSA:3.50.50.60 15 93 1.2E-15 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 Gene3D G3DSA:3.50.50.60 141 199 1.2E-15 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 4.4E-5 T 23-04-2016 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 176 191 4.4E-5 T 23-04-2016 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 SUPERFAMILY SSF51971 281 337 3.06E-27 T 23-04-2016 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 SUPERFAMILY SSF51971 16 219 3.06E-27 T 23-04-2016 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 Gene3D G3DSA:3.30.9.10 200 294 5.0E-38 T 23-04-2016 DC74_RS33110 b405661e9b9716ec02cacef58fc21353 353 Gene3D G3DSA:3.30.9.10 119 135 5.0E-38 T 23-04-2016 DC74_RS03175 fec275c707c0330a688e6fba7db38a19 140 PANTHER PTHR30007 1 112 1.8E-31 T 23-04-2016 DC74_RS03175 fec275c707c0330a688e6fba7db38a19 140 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 78 1.8E-25 T 23-04-2016 IPR025161 Putative transposase IS4/IS5 family DC74_RS03175 fec275c707c0330a688e6fba7db38a19 140 PANTHER PTHR30007:SF0 1 112 1.8E-31 T 23-04-2016 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 Pfam PF12833 Helix-turn-helix domain 104 181 6.5E-19 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 135 177 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 Gene3D G3DSA:1.10.340.30 326 440 7.2E-23 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 SUPERFAMILY SSF57884 2 81 4.58E-31 T 23-04-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 Gene3D G3DSA:1.10.10.60 136 182 1.9E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 Gene3D G3DSA:3.40.10.10 2 79 3.3E-33 T 23-04-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 Gene3D G3DSA:1.10.10.60 80 135 4.9E-5 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 Gene3D G3DSA:3.30.310.20 203 323 5.1E-30 T 23-04-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal DC74_RS35805 e05a2194f67097c0af951669686afa49 489 SMART SM00478 333 472 0.0015 T 23-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 Pfam PF06029 AlkA N-terminal domain 203 323 2.9E-29 T 23-04-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal DC74_RS35805 e05a2194f67097c0af951669686afa49 489 PANTHER PTHR10242:SF3 270 468 5.6E-52 T 23-04-2016 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 PANTHER PTHR10242:SF3 203 249 5.6E-52 T 23-04-2016 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 SUPERFAMILY SSF46689 135 182 3.9E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 SMART SM00342 98 181 5.5E-20 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 SUPERFAMILY SSF55945 203 304 2.2E-19 T 23-04-2016 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 PANTHER PTHR10242 270 468 5.6E-52 T 23-04-2016 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 PANTHER PTHR10242 203 249 5.6E-52 T 23-04-2016 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 SMART SM01009 202 323 8.5E-39 T 23-04-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal DC74_RS35805 e05a2194f67097c0af951669686afa49 489 SUPERFAMILY SSF48150 314 469 3.31E-25 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS35805 e05a2194f67097c0af951669686afa49 489 Pfam PF02805 Metal binding domain of Ada 6 69 4.0E-29 T 23-04-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 DC74_RS15640 aa91ae59f7e8e68ed38e2d747ab9b4ee 435 Gene3D G3DSA:1.10.510.10 103 313 6.5E-56 T 23-04-2016 DC74_RS15640 aa91ae59f7e8e68ed38e2d747ab9b4ee 435 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 13 36 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS15640 aa91ae59f7e8e68ed38e2d747ab9b4ee 435 SMART SM00220 7 263 5.8E-73 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS15640 aa91ae59f7e8e68ed38e2d747ab9b4ee 435 Pfam PF00069 Protein kinase domain 8 260 1.5E-53 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS15640 aa91ae59f7e8e68ed38e2d747ab9b4ee 435 Gene3D G3DSA:3.30.200.20 4 102 1.7E-24 T 23-04-2016 DC74_RS15640 aa91ae59f7e8e68ed38e2d747ab9b4ee 435 SUPERFAMILY SSF56112 3 307 9.47E-85 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS15640 aa91ae59f7e8e68ed38e2d747ab9b4ee 435 PANTHER PTHR24362 2 262 3.8E-100 T 23-04-2016 DC74_RS15640 aa91ae59f7e8e68ed38e2d747ab9b4ee 435 PANTHER PTHR24362:SF160 2 262 3.8E-100 T 23-04-2016 DC74_RS15640 aa91ae59f7e8e68ed38e2d747ab9b4ee 435 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 125 137 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS38250 e34983a1d1050eac72839d36b4a8377d 199 Pfam PF03358 NADPH-dependent FMN reductase 20 164 6.8E-12 T 23-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 DC74_RS38250 e34983a1d1050eac72839d36b4a8377d 199 Gene3D G3DSA:3.40.50.360 20 194 6.8E-21 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS38250 e34983a1d1050eac72839d36b4a8377d 199 PANTHER PTHR10204:SF5 17 173 2.1E-14 T 23-04-2016 DC74_RS38250 e34983a1d1050eac72839d36b4a8377d 199 SUPERFAMILY SSF52218 20 195 1.55E-25 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS38250 e34983a1d1050eac72839d36b4a8377d 199 PANTHER PTHR10204 17 173 2.1E-14 T 23-04-2016 DC74_RS07580 64eee3601c321b9ea20778b04c5d3cbd 320 Pfam PF00248 Aldo/keto reductase family 16 319 4.6E-49 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS07580 64eee3601c321b9ea20778b04c5d3cbd 320 PANTHER PTHR11732 1 318 2.6E-77 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS07580 64eee3601c321b9ea20778b04c5d3cbd 320 SUPERFAMILY SSF51430 1 319 1.44E-72 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS07580 64eee3601c321b9ea20778b04c5d3cbd 320 Gene3D G3DSA:3.20.20.100 1 319 4.0E-73 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS12225 f2bbb1f0ce751adcd494bcfe1feacbc8 347 SMART SM00354 13 85 1.6E-15 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS12225 f2bbb1f0ce751adcd494bcfe1feacbc8 347 Gene3D G3DSA:3.40.50.2300 68 187 2.9E-13 T 23-04-2016 DC74_RS12225 f2bbb1f0ce751adcd494bcfe1feacbc8 347 SUPERFAMILY SSF47413 14 72 1.3E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS12225 f2bbb1f0ce751adcd494bcfe1feacbc8 347 Pfam PF13377 Periplasmic binding protein-like domain 186 346 9.6E-18 T 23-04-2016 DC74_RS12225 f2bbb1f0ce751adcd494bcfe1feacbc8 347 Gene3D G3DSA:1.10.260.40 15 67 9.2E-20 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS12225 f2bbb1f0ce751adcd494bcfe1feacbc8 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 61 9.1E-13 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS12225 f2bbb1f0ce751adcd494bcfe1feacbc8 347 PANTHER PTHR30146:SF48 13 346 7.4E-61 T 23-04-2016 DC74_RS12225 f2bbb1f0ce751adcd494bcfe1feacbc8 347 PANTHER PTHR30146 13 346 7.4E-61 T 23-04-2016 DC74_RS12225 f2bbb1f0ce751adcd494bcfe1feacbc8 347 Gene3D G3DSA:3.40.50.2300 188 309 1.0E-20 T 23-04-2016 DC74_RS12225 f2bbb1f0ce751adcd494bcfe1feacbc8 347 SUPERFAMILY SSF53822 87 310 8.75E-27 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 290 4.7E-87 T 23-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 9.2E-31 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 9.2E-31 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 9.2E-31 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 9.2E-31 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 PANTHER PTHR12128 1 293 3.3E-131 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 Pfam PF00701 Dihydrodipicolinate synthetase family 11 293 2.0E-84 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 PIRSF PIRSF001365 7 298 4.5E-83 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 PANTHER PTHR12128:SF34 1 293 3.3E-131 T 23-04-2016 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 Gene3D G3DSA:3.20.20.70 9 295 5.5E-109 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 SMART SM01130 10 295 2.9E-124 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 SUPERFAMILY SSF51569 7 294 4.5E-98 T 23-04-2016 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 47 64 - T 23-04-2016 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 10 294 58.237 T 23-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28610 f4871cc45b71124fcefdbd78b7d0972b 299 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 23-04-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS08410 fd64fed3c093748bbdaba3a1f1cfecf4 445 PANTHER PTHR24095:SF175 68 444 1.6E-191 T 23-04-2016 DC74_RS08410 fd64fed3c093748bbdaba3a1f1cfecf4 445 SUPERFAMILY SSF56801 33 398 2.22E-63 T 23-04-2016 DC74_RS08410 fd64fed3c093748bbdaba3a1f1cfecf4 445 Pfam PF00501 AMP-binding enzyme 106 302 1.4E-15 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS08410 fd64fed3c093748bbdaba3a1f1cfecf4 445 PANTHER PTHR24095 68 444 1.6E-191 T 23-04-2016 DC74_RS08410 fd64fed3c093748bbdaba3a1f1cfecf4 445 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 24 442 1.7E-211 T 23-04-2016 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716|UniPathway: UPA00930 DC74_RS08410 fd64fed3c093748bbdaba3a1f1cfecf4 445 Gene3D G3DSA:3.30.300.30 339 443 6.0E-33 T 23-04-2016 DC74_RS08410 fd64fed3c093748bbdaba3a1f1cfecf4 445 PIRSF PIRSF006444 14 444 4.8E-201 T 23-04-2016 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716|UniPathway: UPA00930 DC74_RS08410 fd64fed3c093748bbdaba3a1f1cfecf4 445 Gene3D G3DSA:3.40.50.980 105 261 5.2E-14 T 23-04-2016 DC74_RS08410 fd64fed3c093748bbdaba3a1f1cfecf4 445 Pfam PF14535 AMP-binding enzyme C-terminal domain 349 442 3.1E-24 T 23-04-2016 IPR028154 AMP-dependent ligase, C-terminal DC74_RS24335 bff5c656f0313eebbe1bfbbd6488f503 443 SUPERFAMILY SSF55874 306 422 1.2E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS24335 bff5c656f0313eebbe1bfbbd6488f503 443 Pfam PF13581 Histidine kinase-like ATPase domain 298 388 3.9E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS24335 bff5c656f0313eebbe1bfbbd6488f503 443 PANTHER PTHR24421:SF1 86 97 1.3E-23 T 23-04-2016 DC74_RS24335 bff5c656f0313eebbe1bfbbd6488f503 443 PANTHER PTHR24421:SF1 235 440 1.3E-23 T 23-04-2016 DC74_RS24335 bff5c656f0313eebbe1bfbbd6488f503 443 PANTHER PTHR24421 86 97 1.3E-23 T 23-04-2016 DC74_RS24335 bff5c656f0313eebbe1bfbbd6488f503 443 PANTHER PTHR24421 235 440 1.3E-23 T 23-04-2016 DC74_RS24335 bff5c656f0313eebbe1bfbbd6488f503 443 Pfam PF04024 PspC domain 24 79 4.9E-15 T 23-04-2016 IPR007168 Phage shock protein, PspC, N-terminal DC74_RS24335 bff5c656f0313eebbe1bfbbd6488f503 443 Gene3D G3DSA:3.30.565.10 338 425 4.5E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17080 1ae166bdacc030b2942f3706db079840 179 Gene3D G3DSA:2.40.320.10 5 148 1.9E-19 T 23-04-2016 IPR023577 CYTH domain DC74_RS17080 1ae166bdacc030b2942f3706db079840 179 SUPERFAMILY SSF55154 5 152 2.4E-14 T 23-04-2016 IPR033469 CYTH-like domain DC74_RS09390 e6cd5fdb8702c4ac6f76bf84a720c9f1 709 Hamap MF_00983 Probable primosomal protein N' [priA]. 53 708 20.407 T 23-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 DC74_RS09390 e6cd5fdb8702c4ac6f76bf84a720c9f1 709 PANTHER PTHR30580 38 709 3.7E-158 T 23-04-2016 DC74_RS32270 c74763492d9aa9ce073bb652a59c87b0 213 SUPERFAMILY SSF48498 69 194 2.86E-16 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS32270 c74763492d9aa9ce073bb652a59c87b0 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 19 49 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS32270 c74763492d9aa9ce073bb652a59c87b0 213 PANTHER PTHR30328 2 175 2.2E-27 T 23-04-2016 DC74_RS32270 c74763492d9aa9ce073bb652a59c87b0 213 PANTHER PTHR30328:SF29 2 175 2.2E-27 T 23-04-2016 DC74_RS32270 c74763492d9aa9ce073bb652a59c87b0 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 9.5E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS32270 c74763492d9aa9ce073bb652a59c87b0 213 Gene3D G3DSA:1.10.357.10 2 180 1.6E-27 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS32270 c74763492d9aa9ce073bb652a59c87b0 213 SUPERFAMILY SSF46689 2 57 1.03E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS32270 c74763492d9aa9ce073bb652a59c87b0 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 3.8E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS32270 c74763492d9aa9ce073bb652a59c87b0 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 3.8E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS31870 359d14bbbbc6c3604eb44282c0595c21 227 Gene3D G3DSA:1.10.357.10 16 198 2.2E-24 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS31870 359d14bbbbc6c3604eb44282c0595c21 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 8.2E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS31870 359d14bbbbc6c3604eb44282c0595c21 227 PANTHER PTHR30055 8 197 8.4E-18 T 23-04-2016 DC74_RS31870 359d14bbbbc6c3604eb44282c0595c21 227 SUPERFAMILY SSF46689 19 93 1.18E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS31870 359d14bbbbc6c3604eb44282c0595c21 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.0E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS31870 359d14bbbbc6c3604eb44282c0595c21 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 2.0E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37045 ba94c5a0fe395a566e422774da7bc88b 299 PIRSF PIRSF000164 1 280 8.9E-38 T 23-04-2016 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Reactome: REACT_1698 DC74_RS37045 ba94c5a0fe395a566e422774da7bc88b 299 SUPERFAMILY SSF51395 4 262 3.66E-47 T 23-04-2016 DC74_RS37045 ba94c5a0fe395a566e422774da7bc88b 299 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 231 251 - T 23-04-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 DC74_RS37045 ba94c5a0fe395a566e422774da7bc88b 299 Gene3D G3DSA:3.20.20.70 4 263 1.4E-50 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS37045 ba94c5a0fe395a566e422774da7bc88b 299 Pfam PF01180 Dihydroorotate dehydrogenase 3 273 2.2E-25 T 23-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 DC74_RS26750 86877a6294db13bb97ec5b655d58660d 191 SUPERFAMILY SSF52540 14 187 7.92E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26750 86877a6294db13bb97ec5b655d58660d 191 Pfam PF03029 Conserved hypothetical ATP binding protein 19 187 2.7E-27 T 23-04-2016 IPR004130 GPN-loop GTPase DC74_RS26750 86877a6294db13bb97ec5b655d58660d 191 PANTHER PTHR11711:SF117 16 181 1.6E-59 T 23-04-2016 DC74_RS26750 86877a6294db13bb97ec5b655d58660d 191 Gene3D G3DSA:3.40.50.300 9 181 1.8E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26750 86877a6294db13bb97ec5b655d58660d 191 PANTHER PTHR11711 16 181 1.6E-59 T 23-04-2016 DC74_RS27910 72b438a10eee846373ac58d1cd157aa0 197 PANTHER PTHR11670 1 192 2.6E-98 T 23-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27910 72b438a10eee846373ac58d1cd157aa0 197 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 6.1E-57 T 23-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27910 72b438a10eee846373ac58d1cd157aa0 197 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 40.132 T 23-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27910 72b438a10eee846373ac58d1cd157aa0 197 Gene3D G3DSA:3.20.19.10 1 187 9.1E-43 T 23-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel DC74_RS27910 72b438a10eee846373ac58d1cd157aa0 197 Pfam PF00694 Aconitase C-terminal domain 1 117 5.2E-27 T 23-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27910 72b438a10eee846373ac58d1cd157aa0 197 PANTHER PTHR11670:SF27 1 192 2.6E-98 T 23-04-2016 DC74_RS27910 72b438a10eee846373ac58d1cd157aa0 197 SUPERFAMILY SSF52016 1 188 1.39E-53 T 23-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 Pfam PF07690 Major Facilitator Superfamily 28 420 1.7E-49 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 Gene3D G3DSA:1.20.1250.20 267 431 1.0E-12 T 23-04-2016 DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 PANTHER PTHR23501 7 519 2.5E-169 T 23-04-2016 DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 ProSitePatterns PS00216 Sugar transport proteins signature 1. 78 94 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 Gene3D G3DSA:1.20.1250.20 20 209 3.8E-35 T 23-04-2016 DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 SUPERFAMILY SSF103473 468 497 1.13E-60 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 SUPERFAMILY SSF103473 259 430 1.13E-60 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 SUPERFAMILY SSF103473 21 213 1.13E-60 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 1.8E-11 T 23-04-2016 DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 87 109 1.8E-11 T 23-04-2016 DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 1.8E-11 T 23-04-2016 DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 411 430 1.8E-11 T 23-04-2016 DC74_RS21510 7aa49e6108527bbab9ab55581a0a2b0a 519 PANTHER PTHR23501:SF48 7 519 2.5E-169 T 23-04-2016 DC74_RS14865 4955b961d2bed9abaffb26ac862bb12e 485 PANTHER PTHR31806 31 485 1.4E-57 T 23-04-2016 DC74_RS14865 4955b961d2bed9abaffb26ac862bb12e 485 PIRSF PIRSF002744 7 485 3.3E-97 T 23-04-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 DC74_RS14865 4955b961d2bed9abaffb26ac862bb12e 485 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 44 462 1.5E-40 T 23-04-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 DC74_RS18630 433aaefc02056f99610ecff053520b6a 278 Hamap MF_01974 Methionine aminopeptidase [map]. 2 258 37.102 T 23-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 DC74_RS18630 433aaefc02056f99610ecff053520b6a 278 Gene3D G3DSA:3.90.230.10 3 259 2.7E-76 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS18630 433aaefc02056f99610ecff053520b6a 278 PANTHER PTHR10804:SF41 1 256 3.6E-99 T 23-04-2016 DC74_RS18630 433aaefc02056f99610ecff053520b6a 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 212 1.3E-21 T 23-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase DC74_RS18630 433aaefc02056f99610ecff053520b6a 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.3E-21 T 23-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase DC74_RS18630 433aaefc02056f99610ecff053520b6a 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 1.3E-21 T 23-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase DC74_RS18630 433aaefc02056f99610ecff053520b6a 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 1.3E-21 T 23-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase DC74_RS18630 433aaefc02056f99610ecff053520b6a 278 SUPERFAMILY SSF55920 3 256 3.27E-73 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS18630 433aaefc02056f99610ecff053520b6a 278 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 173 191 - T 23-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 DC74_RS18630 433aaefc02056f99610ecff053520b6a 278 Pfam PF00557 Metallopeptidase family M24 11 249 2.2E-41 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS18630 433aaefc02056f99610ecff053520b6a 278 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 257 6.6E-81 T 23-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 DC74_RS18630 433aaefc02056f99610ecff053520b6a 278 PANTHER PTHR10804 1 256 3.6E-99 T 23-04-2016 DC74_RS10650 4a88c89af141e245d37e7e9cfe58b0ab 418 Pfam PF00083 Sugar (and other) transporter 229 416 6.5E-9 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS10650 4a88c89af141e245d37e7e9cfe58b0ab 418 Pfam PF00083 Sugar (and other) transporter 6 216 1.2E-24 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS10650 4a88c89af141e245d37e7e9cfe58b0ab 418 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS10650 4a88c89af141e245d37e7e9cfe58b0ab 418 Gene3D G3DSA:1.20.1250.20 3 207 9.3E-23 T 23-04-2016 DC74_RS10650 4a88c89af141e245d37e7e9cfe58b0ab 418 Gene3D G3DSA:1.20.1250.20 229 414 6.4E-17 T 23-04-2016 DC74_RS10650 4a88c89af141e245d37e7e9cfe58b0ab 418 PANTHER PTHR23508 2 418 4.6E-179 T 23-04-2016 DC74_RS10650 4a88c89af141e245d37e7e9cfe58b0ab 418 SUPERFAMILY SSF103473 2 415 1.07E-62 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS10650 4a88c89af141e245d37e7e9cfe58b0ab 418 PANTHER PTHR23508:SF16 2 418 4.6E-179 T 23-04-2016 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 Pfam PF01494 FAD binding domain 5 357 1.2E-94 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 1.0E-40 T 23-04-2016 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 343 1.0E-40 T 23-04-2016 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 343 359 1.0E-40 T 23-04-2016 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 1.0E-40 T 23-04-2016 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 1.0E-40 T 23-04-2016 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.0E-40 T 23-04-2016 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 PANTHER PTHR13789:SF90 3 358 2.6E-68 T 23-04-2016 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 SUPERFAMILY SSF51905 5 184 2.0E-52 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 SUPERFAMILY SSF51905 279 361 2.0E-52 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 PANTHER PTHR13789 3 358 2.6E-68 T 23-04-2016 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 Gene3D G3DSA:3.50.50.60 4 70 3.4E-48 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 Gene3D G3DSA:3.50.50.60 280 360 3.4E-48 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37710 cee6a4b70dee2b542a4d9a3ab10a4f1c 532 Gene3D G3DSA:3.50.50.60 105 189 3.4E-48 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS27455 a0729bb3e386bee458e1740939867e8e 460 PANTHER PTHR30182:SF1 3 457 2.2E-234 T 23-04-2016 DC74_RS27455 a0729bb3e386bee458e1740939867e8e 460 Pfam PF03313 Serine dehydratase alpha chain 193 454 4.0E-104 T 23-04-2016 IPR005130 Serine dehydratase-like, alpha subunit DC74_RS27455 a0729bb3e386bee458e1740939867e8e 460 Pfam PF03315 Serine dehydratase beta chain 4 162 8.2E-58 T 23-04-2016 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 DC74_RS27455 a0729bb3e386bee458e1740939867e8e 460 SUPERFAMILY SSF143548 17 164 7.85E-44 T 23-04-2016 IPR029009 Allosteric substrate binding domain DC74_RS27455 a0729bb3e386bee458e1740939867e8e 460 Gene3D G3DSA:3.30.1330.90 11 164 1.8E-53 T 23-04-2016 IPR029009 Allosteric substrate binding domain DC74_RS27455 a0729bb3e386bee458e1740939867e8e 460 PANTHER PTHR30182 3 457 2.2E-234 T 23-04-2016 DC74_RS27455 a0729bb3e386bee458e1740939867e8e 460 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 457 4.4E-208 T 23-04-2016 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 DC74_RS05960 167ca41bf4b99aab875fdf30cc54f0fc 683 Gene3D G3DSA:2.170.16.10 428 574 3.4E-17 T 23-04-2016 IPR028992 Hedgehog/Intein (Hint) domain DC74_RS05960 167ca41bf4b99aab875fdf30cc54f0fc 683 SUPERFAMILY SSF51294 431 573 2.49E-15 T 23-04-2016 IPR028992 Hedgehog/Intein (Hint) domain DC74_RS05960 167ca41bf4b99aab875fdf30cc54f0fc 683 Pfam PF07591 Pretoxin HINT domain 447 572 2.5E-15 T 23-04-2016 DC74_RS05960 167ca41bf4b99aab875fdf30cc54f0fc 683 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 548 573 7.7E-6 T 23-04-2016 IPR030934 Intein C-terminal splicing region DC74_RS20950 ee8df4d9dbee20e4b7298108863cc738 125 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 115 3.4E-31 T 23-04-2016 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV DC74_RS20950 ee8df4d9dbee20e4b7298108863cc738 125 PANTHER PTHR37309 2 123 2.7E-36 T 23-04-2016 DC74_RS20950 ee8df4d9dbee20e4b7298108863cc738 125 PANTHER PTHR37309:SF1 2 123 2.7E-36 T 23-04-2016 DC74_RS13965 c0b994fc638a8ec4b319640decbd5844 533 Gene3D G3DSA:1.20.1250.20 21 214 3.8E-35 T 23-04-2016 DC74_RS13965 c0b994fc638a8ec4b319640decbd5844 533 Pfam PF07690 Major Facilitator Superfamily 34 426 2.4E-52 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS13965 c0b994fc638a8ec4b319640decbd5844 533 PANTHER PTHR23501:SF48 17 467 5.7E-185 T 23-04-2016 DC74_RS13965 c0b994fc638a8ec4b319640decbd5844 533 PANTHER PTHR23501:SF48 483 524 5.7E-185 T 23-04-2016 DC74_RS13965 c0b994fc638a8ec4b319640decbd5844 533 Gene3D G3DSA:1.20.1250.20 285 437 8.0E-23 T 23-04-2016 DC74_RS13965 c0b994fc638a8ec4b319640decbd5844 533 Gene3D G3DSA:1.20.1250.20 496 520 8.0E-23 T 23-04-2016 DC74_RS13965 c0b994fc638a8ec4b319640decbd5844 533 SUPERFAMILY SSF103473 495 520 1.7E-75 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS13965 c0b994fc638a8ec4b319640decbd5844 533 SUPERFAMILY SSF103473 265 436 1.7E-75 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS13965 c0b994fc638a8ec4b319640decbd5844 533 SUPERFAMILY SSF103473 3 213 1.7E-75 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS13965 c0b994fc638a8ec4b319640decbd5844 533 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 30 518 1.3E-86 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS13965 c0b994fc638a8ec4b319640decbd5844 533 PANTHER PTHR23501 17 467 5.7E-185 T 23-04-2016 DC74_RS13965 c0b994fc638a8ec4b319640decbd5844 533 PANTHER PTHR23501 483 524 5.7E-185 T 23-04-2016 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 SUPERFAMILY SSF55785 135 256 1.38E-13 T 23-04-2016 IPR000014 PAS domain DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 SMART SM00091 141 207 0.2 T 23-04-2016 IPR000014 PAS domain DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 SMART SM00091 19 86 8.2E-10 T 23-04-2016 IPR000014 PAS domain DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 Gene3D G3DSA:3.30.450.20 24 129 6.5E-23 T 23-04-2016 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 SMART SM00331 481 692 5.2E-36 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 SUPERFAMILY SSF55781 359 462 4.36E-18 T 23-04-2016 IPR029016 GAF domain-like DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 508 692 2.7E-49 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 Gene3D G3DSA:3.30.450.20 135 258 5.5E-19 T 23-04-2016 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 Pfam PF01590 GAF domain 293 450 8.9E-14 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 PANTHER PTHR21021:SF19 404 696 7.6E-63 T 23-04-2016 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 Pfam PF08448 PAS fold 148 260 3.2E-20 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 PANTHER PTHR21021 404 696 7.6E-63 T 23-04-2016 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 Pfam PF00989 PAS fold 25 129 2.3E-14 T 23-04-2016 IPR013767 PAS fold GO:0006355 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 SUPERFAMILY SSF55785 24 129 4.75E-24 T 23-04-2016 IPR000014 PAS domain DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 SMART SM00065 291 460 1.3E-6 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 SUPERFAMILY SSF81606 494 693 5.62E-12 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 146 263 5.7E-7 T 23-04-2016 IPR000014 PAS domain DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 29 129 3.3E-16 T 23-04-2016 IPR000014 PAS domain DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 Gene3D G3DSA:3.60.40.10 618 691 5.8E-4 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS35990 b699e9798b730f9383cd504e5df5cc13 697 Gene3D G3DSA:3.30.450.40 276 457 7.9E-35 T 23-04-2016 IPR029016 GAF domain-like DC74_RS00510 ee7eaf279b54678e3bbd4415b51ce7ca 233 Gene3D G3DSA:3.40.50.2300 1 130 2.4E-41 T 23-04-2016 DC74_RS00510 ee7eaf279b54678e3bbd4415b51ce7ca 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 3.5E-24 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS00510 ee7eaf279b54678e3bbd4415b51ce7ca 233 SUPERFAMILY SSF46894 138 230 4.82E-26 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS00510 ee7eaf279b54678e3bbd4415b51ce7ca 233 SMART SM00862 154 230 3.2E-21 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS00510 ee7eaf279b54678e3bbd4415b51ce7ca 233 SUPERFAMILY SSF52172 1 125 4.41E-41 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS00510 ee7eaf279b54678e3bbd4415b51ce7ca 233 Gene3D G3DSA:1.10.10.10 137 231 1.3E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00510 ee7eaf279b54678e3bbd4415b51ce7ca 233 PANTHER PTHR26402:SF578 2 232 6.5E-90 T 23-04-2016 DC74_RS00510 ee7eaf279b54678e3bbd4415b51ce7ca 233 PANTHER PTHR26402 2 232 6.5E-90 T 23-04-2016 DC74_RS00510 ee7eaf279b54678e3bbd4415b51ce7ca 233 Pfam PF00072 Response regulator receiver domain 4 108 8.7E-28 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS00510 ee7eaf279b54678e3bbd4415b51ce7ca 233 SMART SM00448 2 112 1.5E-42 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS37400 453650c24213a74b7bb31b1bbb1f29de 788 Pfam PF05729 NACHT domain 196 350 2.0E-7 T 23-04-2016 DC74_RS37400 453650c24213a74b7bb31b1bbb1f29de 788 SMART SM00530 8 64 2.3E-14 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS37400 453650c24213a74b7bb31b1bbb1f29de 788 SUPERFAMILY SSF52540 179 352 1.8E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37400 453650c24213a74b7bb31b1bbb1f29de 788 Pfam PF13560 Helix-turn-helix domain 4 67 1.5E-13 T 23-04-2016 DC74_RS37400 453650c24213a74b7bb31b1bbb1f29de 788 Gene3D G3DSA:1.10.260.40 3 63 1.1E-15 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS37400 453650c24213a74b7bb31b1bbb1f29de 788 SUPERFAMILY SSF47413 4 63 6.44E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS29400 3c0b84f77b66dbf944eaf06af6b23385 381 SUPERFAMILY SSF47203 221 375 1.3E-49 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS29400 3c0b84f77b66dbf944eaf06af6b23385 381 SUPERFAMILY SSF56645 4 233 2.36E-51 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS29400 3c0b84f77b66dbf944eaf06af6b23385 381 PANTHER PTHR10909:SF305 4 376 1.8E-138 T 23-04-2016 DC74_RS29400 3c0b84f77b66dbf944eaf06af6b23385 381 Gene3D G3DSA:2.40.110.10 117 212 3.4E-29 T 23-04-2016 DC74_RS29400 3c0b84f77b66dbf944eaf06af6b23385 381 Gene3D G3DSA:1.20.140.10 213 377 3.2E-56 T 23-04-2016 DC74_RS29400 3c0b84f77b66dbf944eaf06af6b23385 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 113 7.5E-12 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS29400 3c0b84f77b66dbf944eaf06af6b23385 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 118 209 3.7E-21 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS29400 3c0b84f77b66dbf944eaf06af6b23385 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 223 372 7.7E-47 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS29400 3c0b84f77b66dbf944eaf06af6b23385 381 PANTHER PTHR10909 4 376 1.8E-138 T 23-04-2016 DC74_RS29400 3c0b84f77b66dbf944eaf06af6b23385 381 Gene3D G3DSA:1.10.540.10 4 114 1.5E-16 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS29400 3c0b84f77b66dbf944eaf06af6b23385 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 120 132 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS28240 e72c0e2af9658af272a67a6575622128 384 Gene3D G3DSA:3.30.565.10 297 383 5.7E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28240 e72c0e2af9658af272a67a6575622128 384 PANTHER PTHR24421 44 384 6.4E-80 T 23-04-2016 DC74_RS28240 e72c0e2af9658af272a67a6575622128 384 PANTHER PTHR24421:SF26 44 384 6.4E-80 T 23-04-2016 DC74_RS28240 e72c0e2af9658af272a67a6575622128 384 SUPERFAMILY SSF55874 267 383 2.11E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28240 e72c0e2af9658af272a67a6575622128 384 Pfam PF07730 Histidine kinase 186 251 5.7E-18 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS27055 3ae9e714359000f02c22de3f558a7471 267 PANTHER PTHR12215 29 223 1.4E-26 T 23-04-2016 DC74_RS27055 3ae9e714359000f02c22de3f558a7471 267 Gene3D G3DSA:3.90.470.20 43 151 3.9E-22 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS27055 3ae9e714359000f02c22de3f558a7471 267 Gene3D G3DSA:3.90.470.20 152 247 7.3E-19 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS27055 3ae9e714359000f02c22de3f558a7471 267 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 142 228 2.2E-14 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS27055 3ae9e714359000f02c22de3f558a7471 267 SUPERFAMILY SSF56214 39 133 9.42E-15 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS27055 3ae9e714359000f02c22de3f558a7471 267 SUPERFAMILY SSF56214 141 255 1.7E-22 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS25485 00abb613723e5711cebb569fbc657319 445 Gene3D G3DSA:3.40.50.300 234 440 1.3E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25485 00abb613723e5711cebb569fbc657319 445 Pfam PF13638 PIN domain 15 158 1.1E-24 T 23-04-2016 IPR002716 PIN domain DC74_RS25485 00abb613723e5711cebb569fbc657319 445 PANTHER PTHR30473 12 445 2.9E-182 T 23-04-2016 DC74_RS25485 00abb613723e5711cebb569fbc657319 445 SUPERFAMILY SSF88723 110 156 1.96E-7 T 23-04-2016 IPR029060 PIN domain-like DC74_RS25485 00abb613723e5711cebb569fbc657319 445 SUPERFAMILY SSF88723 14 72 1.96E-7 T 23-04-2016 IPR029060 PIN domain-like DC74_RS25485 00abb613723e5711cebb569fbc657319 445 Pfam PF02562 PhoH-like protein 235 440 4.7E-54 T 23-04-2016 IPR003714 PhoH-like protein GO:0005524 DC74_RS25485 00abb613723e5711cebb569fbc657319 445 SMART SM00670 13 145 1.0E-11 T 23-04-2016 IPR002716 PIN domain DC74_RS25485 00abb613723e5711cebb569fbc657319 445 SUPERFAMILY SSF52540 234 397 1.18E-17 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25485 00abb613723e5711cebb569fbc657319 445 PANTHER PTHR30473:SF2 12 445 2.9E-182 T 23-04-2016 DC74_RS25485 00abb613723e5711cebb569fbc657319 445 Gene3D G3DSA:3.40.50.1010 14 72 4.0E-10 T 23-04-2016 IPR029060 PIN domain-like DC74_RS25485 00abb613723e5711cebb569fbc657319 445 Gene3D G3DSA:3.40.50.1010 110 158 4.0E-10 T 23-04-2016 IPR029060 PIN domain-like DC74_RS26510 66a1e8e4b1688a8b43420e47d7f70049 533 Pfam PF00999 Sodium/hydrogen exchanger family 9 404 1.3E-60 T 23-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 DC74_RS26510 66a1e8e4b1688a8b43420e47d7f70049 533 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 525 1.6E-99 T 23-04-2016 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 DC74_RS26510 66a1e8e4b1688a8b43420e47d7f70049 533 PANTHER PTHR10110:SF86 21 521 5.6E-106 T 23-04-2016 DC74_RS26510 66a1e8e4b1688a8b43420e47d7f70049 533 PANTHER PTHR10110 21 521 5.6E-106 T 23-04-2016 IPR018422 Cation/H+ exchanger, CPA1 family GO:0006812|GO:0015299|GO:0016021 Reactome: REACT_15518 DC74_RS40305 edc4bd8111f3f9d8a3f3657624f184c9 128 PANTHER PTHR26402:SF292 1 97 2.3E-27 T 23-04-2016 DC74_RS40305 edc4bd8111f3f9d8a3f3657624f184c9 128 SMART SM00862 20 95 3.6E-20 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS40305 edc4bd8111f3f9d8a3f3657624f184c9 128 Pfam PF00486 Transcriptional regulatory protein, C terminal 20 95 8.2E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS40305 edc4bd8111f3f9d8a3f3657624f184c9 128 SUPERFAMILY SSF46894 2 96 4.25E-22 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS40305 edc4bd8111f3f9d8a3f3657624f184c9 128 Gene3D G3DSA:1.10.10.10 1 97 3.5E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS40305 edc4bd8111f3f9d8a3f3657624f184c9 128 PANTHER PTHR26402 1 97 2.3E-27 T 23-04-2016 DC74_RS31620 17dabf3640a8f7a4ef796b1f4d3e3900 143 PANTHER PTHR39515:SF1 1 142 4.8E-32 T 23-04-2016 DC74_RS31620 17dabf3640a8f7a4ef796b1f4d3e3900 143 Gene3D G3DSA:1.10.10.10 32 96 7.6E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31620 17dabf3640a8f7a4ef796b1f4d3e3900 143 SUPERFAMILY SSF46785 3 140 1.12E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31620 17dabf3640a8f7a4ef796b1f4d3e3900 143 PANTHER PTHR39515 1 142 4.8E-32 T 23-04-2016 DC74_RS31620 17dabf3640a8f7a4ef796b1f4d3e3900 143 Gene3D G3DSA:1.10.287.100 97 142 1.9E-13 T 23-04-2016 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 DC74_RS31620 17dabf3640a8f7a4ef796b1f4d3e3900 143 SMART SM00347 26 127 3.5E-14 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS31620 17dabf3640a8f7a4ef796b1f4d3e3900 143 Pfam PF01047 MarR family 33 91 6.6E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS10110 c1813340e40f7fce91aaf04c70a01115 193 SUPERFAMILY SSF55200 70 154 7.98E-32 T 23-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 DC74_RS10110 c1813340e40f7fce91aaf04c70a01115 193 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 69 152 9.4E-34 T 23-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 DC74_RS10110 c1813340e40f7fce91aaf04c70a01115 193 Gene3D G3DSA:3.30.110.10 64 156 2.4E-38 T 23-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 DC74_RS10110 c1813340e40f7fce91aaf04c70a01115 193 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 155 25.55 T 23-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 DC74_RS10110 c1813340e40f7fce91aaf04c70a01115 193 PANTHER PTHR10938 1 174 7.4E-64 T 23-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 DC74_RS10110 c1813340e40f7fce91aaf04c70a01115 193 SUPERFAMILY SSF54364 1 63 4.45E-23 T 23-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 DC74_RS10110 c1813340e40f7fce91aaf04c70a01115 193 Gene3D G3DSA:3.10.20.80 1 63 6.3E-28 T 23-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 DC74_RS10110 c1813340e40f7fce91aaf04c70a01115 193 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 61 4.7E-24 T 23-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 DC74_RS10110 c1813340e40f7fce91aaf04c70a01115 193 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 155 1.7E-56 T 23-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 DC74_RS07360 043285c2b4153b12d33a89db8e240624 368 SUPERFAMILY SSF50494 128 341 4.71E-18 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS07360 043285c2b4153b12d33a89db8e240624 368 Gene3D G3DSA:2.40.10.10 270 339 5.9E-7 T 23-04-2016 DC74_RS07360 043285c2b4153b12d33a89db8e240624 368 Gene3D G3DSA:2.40.10.10 140 243 1.3E-5 T 23-04-2016 DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 Pfam PF00106 short chain dehydrogenase 24 216 8.8E-56 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 PANTHER PTHR24319 23 260 3.5E-53 T 23-04-2016 DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 165 193 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 PIRSF PIRSF000126 5 263 2.3E-54 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 23 235 0.0024 T 23-04-2016 DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 PANTHER PTHR24319:SF32 23 260 3.5E-53 T 23-04-2016 DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 Gene3D G3DSA:3.40.50.720 19 258 1.4E-67 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 1.0E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 166 1.0E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 178 197 1.0E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 SUPERFAMILY SSF51735 19 257 7.49E-66 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 197 1.2E-28 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 1.2E-28 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 1.2E-28 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 168 1.2E-28 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 1.2E-28 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04090 b8a470b08854c8fc72642922ac36cd63 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 1.2E-28 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 SUPERFAMILY SSF51735 19 269 8.79E-74 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 23 270 3.4E-102 T 23-04-2016 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 3.4E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 3.4E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 3.4E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 3.4E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 231 251 3.4E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 3.4E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 2.4E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 2.4E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 2.4E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 PANTHER PTHR24322 165 197 4.8E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 PANTHER PTHR24322 27 149 4.8E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 Gene3D G3DSA:3.40.50.720 22 268 8.9E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 29 268 2.1E-50 T 23-04-2016 DC74_RS08695 d9842cf3ca7bc0b96e4cab8cf975e434 270 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS13070 075b8b4c2394547d4b01f2ed59e9c3a5 370 PANTHER PTHR30595 1 224 3.4E-103 T 23-04-2016 DC74_RS13070 075b8b4c2394547d4b01f2ed59e9c3a5 370 PANTHER PTHR30595 242 349 3.4E-103 T 23-04-2016 DC74_RS13070 075b8b4c2394547d4b01f2ed59e9c3a5 370 PANTHER PTHR30595:SF4 1 224 3.4E-103 T 23-04-2016 DC74_RS13070 075b8b4c2394547d4b01f2ed59e9c3a5 370 PANTHER PTHR30595:SF4 242 349 3.4E-103 T 23-04-2016 DC74_RS13070 075b8b4c2394547d4b01f2ed59e9c3a5 370 Pfam PF08279 HTH domain 5 60 1.3E-14 T 23-04-2016 IPR013196 Helix-turn-helix, type 11 DC74_RS13070 075b8b4c2394547d4b01f2ed59e9c3a5 370 Pfam PF13280 WYL domain 140 356 2.8E-36 T 23-04-2016 IPR026881 WYL domain DC74_RS13070 075b8b4c2394547d4b01f2ed59e9c3a5 370 SUPERFAMILY SSF46785 3 59 4.18E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13070 075b8b4c2394547d4b01f2ed59e9c3a5 370 Gene3D G3DSA:1.10.10.10 1 63 5.8E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS33600 33a41cc01ce5880173b0c413d49cf0c7 206 SUPERFAMILY SSF48498 92 181 6.52E-11 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS33600 33a41cc01ce5880173b0c413d49cf0c7 206 Pfam PF13305 WHG domain 99 180 2.5E-8 T 23-04-2016 IPR025996 WHG domain DC74_RS33600 33a41cc01ce5880173b0c413d49cf0c7 206 Gene3D G3DSA:1.10.357.10 8 204 1.6E-41 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS33600 33a41cc01ce5880173b0c413d49cf0c7 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 1.3E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS33600 33a41cc01ce5880173b0c413d49cf0c7 206 PANTHER PTHR30055:SF23 7 205 2.8E-28 T 23-04-2016 DC74_RS33600 33a41cc01ce5880173b0c413d49cf0c7 206 SUPERFAMILY SSF46689 9 89 4.99E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS33600 33a41cc01ce5880173b0c413d49cf0c7 206 PANTHER PTHR30055 7 205 2.8E-28 T 23-04-2016 DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 23-04-2016 IPR018181 Heat shock protein 70, conserved site DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 Gene3D G3DSA:2.60.34.10 361 503 2.8E-72 T 23-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 Gene3D G3DSA:3.90.640.10 200 285 7.6E-31 T 23-04-2016 DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 PRINTS PR00301 70kDa heat shock protein signature 114 134 4.4E-74 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 PRINTS PR00301 70kDa heat shock protein signature 172 182 4.4E-74 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 PRINTS PR00301 70kDa heat shock protein signature 440 456 4.4E-74 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 PRINTS PR00301 70kDa heat shock protein signature 54 62 4.4E-74 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 PRINTS PR00301 70kDa heat shock protein signature 31 43 4.4E-74 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 PRINTS PR00301 70kDa heat shock protein signature 304 320 4.4E-74 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 PRINTS PR00301 70kDa heat shock protein signature 359 378 4.4E-74 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 PRINTS PR00301 70kDa heat shock protein signature 336 356 4.4E-74 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 PRINTS PR00301 70kDa heat shock protein signature 3 16 4.4E-74 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 PANTHER PTHR19375:SF173 2 618 0.0 T 23-04-2016 DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 Gene3D G3DSA:3.30.420.40 169 199 2.9E-34 T 23-04-2016 DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 Gene3D G3DSA:3.30.420.40 289 331 2.9E-34 T 23-04-2016 DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 609 36.14 T 23-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 SUPERFAMILY SSF53067 160 353 1.67E-65 T 23-04-2016 DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 Gene3D G3DSA:3.30.30.30 39 100 3.8E-17 T 23-04-2016 DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 SUPERFAMILY SSF100920 355 511 1.2E-59 T 23-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 23-04-2016 IPR018181 Heat shock protein 70, conserved site DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 SUPERFAMILY SSF53067 4 160 2.3E-57 T 23-04-2016 DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 Pfam PF00012 Hsp70 protein 83 574 2.2E-219 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 Pfam PF00012 Hsp70 protein 4 78 4.3E-29 T 23-04-2016 IPR013126 Heat shock protein 70 family DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 23-04-2016 IPR018181 Heat shock protein 70, conserved site DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 Gene3D G3DSA:3.30.420.40 101 168 1.1E-55 T 23-04-2016 DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 Gene3D G3DSA:3.30.420.40 4 38 1.1E-55 T 23-04-2016 DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 Gene3D G3DSA:1.20.1270.10 504 574 3.4E-28 T 23-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 PANTHER PTHR19375 2 618 0.0 T 23-04-2016 DC74_RS19955 ef7166958db696ccd1533a4c580cbe21 618 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 574 1.5E-278 T 23-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 Gene3D G3DSA:2.140.10.10 339 717 9.5E-71 T 23-04-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 SUPERFAMILY SSF56112 2 311 9.98E-77 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 PANTHER PTHR24362:SF160 1 334 1.0E-102 T 23-04-2016 DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 SMART SM00564 447 477 19.0 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 SMART SM00564 525 557 2.6E-6 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 SMART SM00564 654 688 6.9E-7 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 SMART SM00564 613 644 1.7E-6 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 SMART SM00564 404 435 70.0 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 SMART SM00564 566 597 6.0E-6 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 SMART SM00564 486 517 9.6E-8 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 125 137 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 Pfam PF00069 Protein kinase domain 5 253 6.7E-50 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 SUPERFAMILY SSF50998 374 709 2.35E-56 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 SMART SM00220 5 260 3.0E-64 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 PANTHER PTHR24362 1 334 1.0E-102 T 23-04-2016 DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 Pfam PF13360 PQQ-like domain 485 601 7.3E-22 T 23-04-2016 IPR002372 Pyrrolo-quinoline quinone repeat DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 Pfam PF13360 PQQ-like domain 386 478 1.8E-10 T 23-04-2016 IPR002372 Pyrrolo-quinoline quinone repeat DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 Pfam PF13360 PQQ-like domain 611 719 6.9E-14 T 23-04-2016 IPR002372 Pyrrolo-quinoline quinone repeat DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 Gene3D G3DSA:3.30.200.20 2 72 1.0E-20 T 23-04-2016 DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 11 34 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS40720 759b928535bc899ec8e58ab0bce28daa 726 Gene3D G3DSA:1.10.510.10 73 266 9.4E-51 T 23-04-2016 DC74_RS21110 bdd727d1cff70ded457ebb8dfb9b5d15 274 Gene3D G3DSA:3.30.160.60 230 263 1.4E-5 T 23-04-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 DC74_RS21110 bdd727d1cff70ded457ebb8dfb9b5d15 274 PANTHER PTHR30518 37 269 2.2E-59 T 23-04-2016 DC74_RS21110 bdd727d1cff70ded457ebb8dfb9b5d15 274 Pfam PF02618 YceG-like family 42 257 4.8E-60 T 23-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like DC74_RS21110 bdd727d1cff70ded457ebb8dfb9b5d15 274 PANTHER PTHR30518:SF2 37 269 2.2E-59 T 23-04-2016 DC74_RS21110 bdd727d1cff70ded457ebb8dfb9b5d15 274 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 93 261 1.9E-42 T 23-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like DC74_RS32965 648eb11eeb0604b60405efbc2cec4d37 293 SUPERFAMILY SSF51569 2 276 7.03E-78 T 23-04-2016 DC74_RS32965 648eb11eeb0604b60405efbc2cec4d37 293 PIRSF PIRSF001359 1 278 1.7E-67 T 23-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 DC74_RS32965 648eb11eeb0604b60405efbc2cec4d37 293 Gene3D G3DSA:3.20.20.70 1 276 2.4E-81 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS32965 648eb11eeb0604b60405efbc2cec4d37 293 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 276 1.1E-75 T 23-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 DC74_RS32965 648eb11eeb0604b60405efbc2cec4d37 293 PANTHER PTHR30304 1 266 4.0E-64 T 23-04-2016 DC74_RS39255 7e8a4d390709938f734f77dd9ad91721 155 Pfam PF00583 Acetyltransferase (GNAT) family 61 142 1.2E-16 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS39255 7e8a4d390709938f734f77dd9ad91721 155 Gene3D G3DSA:3.40.630.30 1 153 9.1E-31 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS39255 7e8a4d390709938f734f77dd9ad91721 155 PANTHER PTHR10545 1 153 5.5E-26 T 23-04-2016 DC74_RS39255 7e8a4d390709938f734f77dd9ad91721 155 SUPERFAMILY SSF55729 1 146 2.84E-30 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS21925 334bb06fd8b60a8343361aaefaf3fd64 809 Gene3D G3DSA:1.20.272.10 246 364 4.7E-14 T 23-04-2016 DC74_RS21925 334bb06fd8b60a8343361aaefaf3fd64 809 PANTHER PTHR11669:SF0 1 378 5.1E-152 T 23-04-2016 DC74_RS21925 334bb06fd8b60a8343361aaefaf3fd64 809 Pfam PF13177 DNA polymerase III, delta subunit 20 178 9.9E-38 T 23-04-2016 DC74_RS21925 334bb06fd8b60a8343361aaefaf3fd64 809 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 236 364 2.8E-13 T 23-04-2016 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 DC74_RS21925 334bb06fd8b60a8343361aaefaf3fd64 809 SUPERFAMILY SSF52540 32 222 1.5E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21925 334bb06fd8b60a8343361aaefaf3fd64 809 SMART SM00382 37 181 5.7E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS21925 334bb06fd8b60a8343361aaefaf3fd64 809 Gene3D G3DSA:1.10.8.60 168 245 8.5E-21 T 23-04-2016 DC74_RS21925 334bb06fd8b60a8343361aaefaf3fd64 809 Gene3D G3DSA:3.40.50.300 15 167 4.9E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21925 334bb06fd8b60a8343361aaefaf3fd64 809 PANTHER PTHR11669 1 378 5.1E-152 T 23-04-2016 DC74_RS21925 334bb06fd8b60a8343361aaefaf3fd64 809 SUPERFAMILY SSF48019 247 365 3.32E-21 T 23-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 DC74_RS21925 334bb06fd8b60a8343361aaefaf3fd64 809 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 5 363 7.0E-117 T 23-04-2016 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 DC74_RS13255 161a27bce6f673c160aba6a15920b288 549 PANTHER PTHR10357 461 510 2.0E-146 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS13255 161a27bce6f673c160aba6a15920b288 549 PANTHER PTHR10357 23 428 2.0E-146 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS13255 161a27bce6f673c160aba6a15920b288 549 SMART SM00642 31 419 3.4E-123 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS13255 161a27bce6f673c160aba6a15920b288 549 Pfam PF11941 Domain of unknown function (DUF3459) 468 547 7.2E-6 T 23-04-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) DC74_RS13255 161a27bce6f673c160aba6a15920b288 549 Gene3D G3DSA:3.20.20.80 23 122 9.4E-108 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS13255 161a27bce6f673c160aba6a15920b288 549 Gene3D G3DSA:3.20.20.80 190 483 9.4E-108 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS13255 161a27bce6f673c160aba6a15920b288 549 Gene3D G3DSA:3.90.400.10 123 188 6.6E-23 T 23-04-2016 DC74_RS13255 161a27bce6f673c160aba6a15920b288 549 Pfam PF00128 Alpha amylase, catalytic domain 46 381 7.0E-78 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS13255 161a27bce6f673c160aba6a15920b288 549 PANTHER PTHR10357:SF11 461 510 2.0E-146 T 23-04-2016 DC74_RS13255 161a27bce6f673c160aba6a15920b288 549 PANTHER PTHR10357:SF11 23 428 2.0E-146 T 23-04-2016 DC74_RS13255 161a27bce6f673c160aba6a15920b288 549 SUPERFAMILY SSF51445 23 482 1.77E-123 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS27330 223acd451efbff64715190d6c47826ac 663 PANTHER PTHR10357 4 130 3.2E-270 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS27330 223acd451efbff64715190d6c47826ac 663 PANTHER PTHR10357 163 656 3.2E-270 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS27330 223acd451efbff64715190d6c47826ac 663 Pfam PF11896 Domain of unknown function (DUF3416) 3 190 6.0E-59 T 23-04-2016 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 DC74_RS27330 223acd451efbff64715190d6c47826ac 663 SUPERFAMILY SSF51011 564 642 8.31E-6 T 23-04-2016 DC74_RS27330 223acd451efbff64715190d6c47826ac 663 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 1 654 45.6 T 23-04-2016 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 DC74_RS27330 223acd451efbff64715190d6c47826ac 663 PANTHER PTHR10357:SF137 4 130 3.2E-270 T 23-04-2016 DC74_RS27330 223acd451efbff64715190d6c47826ac 663 PANTHER PTHR10357:SF137 163 656 3.2E-270 T 23-04-2016 DC74_RS27330 223acd451efbff64715190d6c47826ac 663 Gene3D G3DSA:2.60.40.1180 563 640 4.6E-11 T 23-04-2016 IPR013780 Glycosyl hydrolase, all-beta DC74_RS27330 223acd451efbff64715190d6c47826ac 663 SMART SM00642 196 554 0.0035 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS27330 223acd451efbff64715190d6c47826ac 663 SUPERFAMILY SSF51445 197 559 3.9E-80 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS27330 223acd451efbff64715190d6c47826ac 663 Gene3D G3DSA:3.20.20.80 196 557 1.2E-64 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS12675 7f2a1025ec8a7552b4e9febb046bb9f0 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 2.4E-21 T 23-04-2016 IPR010035 ThiS, thiamine-biosynthesis DC74_RS12675 7f2a1025ec8a7552b4e9febb046bb9f0 66 Pfam PF02597 ThiS family 3 66 6.5E-16 T 23-04-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 DC74_RS12675 7f2a1025ec8a7552b4e9febb046bb9f0 66 Gene3D G3DSA:3.10.20.30 2 66 1.8E-25 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS12675 7f2a1025ec8a7552b4e9febb046bb9f0 66 PANTHER PTHR34472:SF1 2 66 3.2E-19 T 23-04-2016 DC74_RS12675 7f2a1025ec8a7552b4e9febb046bb9f0 66 PANTHER PTHR34472 2 66 3.2E-19 T 23-04-2016 DC74_RS12675 7f2a1025ec8a7552b4e9febb046bb9f0 66 SUPERFAMILY SSF54285 3 65 8.43E-17 T 23-04-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 PANTHER PTHR24322 169 201 3.1E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 PANTHER PTHR24322 17 153 3.1E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 261 3.0E-64 T 23-04-2016 DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 204 0.0017 T 23-04-2016 DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.3E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 1.3E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 1.3E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 1.3E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 1.3E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.3E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 Gene3D G3DSA:3.40.50.720 6 263 2.9E-81 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 SUPERFAMILY SSF51735 8 263 3.01E-78 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 5.4E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03015 85376292e25561d2758110ea30cdbab6 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 5.4E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14600 d1af2c18e6394a4549c8971dbda9f102 339 PANTHER PTHR10314:SF36 18 338 1.3E-135 T 23-04-2016 DC74_RS14600 d1af2c18e6394a4549c8971dbda9f102 339 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 39 326 3.4E-81 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS14600 d1af2c18e6394a4549c8971dbda9f102 339 PANTHER PTHR10314 18 338 1.3E-135 T 23-04-2016 DC74_RS14600 d1af2c18e6394a4549c8971dbda9f102 339 Gene3D G3DSA:3.40.50.1100 93 337 6.0E-74 T 23-04-2016 DC74_RS14600 d1af2c18e6394a4549c8971dbda9f102 339 SUPERFAMILY SSF53686 26 334 7.99E-98 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 10 327 2.8E-89 T 23-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 SUPERFAMILY SSF48163 324 491 1.31E-30 T 23-04-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 PANTHER PTHR11451:SF41 9 342 7.8E-100 T 23-04-2016 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 Gene3D G3DSA:1.10.10.350 394 491 7.3E-20 T 23-04-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 27 38 2.2E-22 T 23-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 42 55 2.2E-22 T 23-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 208 2.2E-22 T 23-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 13 25 2.2E-22 T 23-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 214 222 2.2E-22 T 23-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 Gene3D G3DSA:3.40.50.620 10 74 4.4E-43 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 Gene3D G3DSA:3.40.50.620 200 254 4.4E-43 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 SUPERFAMILY SSF52374 10 323 1.82E-105 T 23-04-2016 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 PANTHER PTHR11451 9 342 7.8E-100 T 23-04-2016 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 10 489 2.5E-137 T 23-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 Gene3D G3DSA:1.10.1160.10 257 339 7.4E-30 T 23-04-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 10 491 31.783 T 23-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 DC74_RS27865 6000d25d3d91f5eab3fd119563fc4b19 496 Gene3D G3DSA:3.90.800.10 75 198 6.6E-41 T 23-04-2016 DC74_RS09630 6da0ba72c2e973d9fca55a8d196f0404 203 PANTHER PTHR31559 1 195 4.0E-92 T 23-04-2016 DC74_RS09630 6da0ba72c2e973d9fca55a8d196f0404 203 PIRSF PIRSF005639 1 197 7.0E-75 T 23-04-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 DC74_RS09630 6da0ba72c2e973d9fca55a8d196f0404 203 PANTHER PTHR31559:SF0 1 195 4.0E-92 T 23-04-2016 DC74_RS09630 6da0ba72c2e973d9fca55a8d196f0404 203 SUPERFAMILY SSF52317 6 193 7.64E-53 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS09630 6da0ba72c2e973d9fca55a8d196f0404 203 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 7 191 5.5E-81 T 23-04-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 DC74_RS09630 6da0ba72c2e973d9fca55a8d196f0404 203 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 7 192 37.427 T 23-04-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 DC74_RS09630 6da0ba72c2e973d9fca55a8d196f0404 203 Gene3D G3DSA:3.40.50.880 4 195 3.5E-79 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS09630 6da0ba72c2e973d9fca55a8d196f0404 203 ProSitePatterns PS01236 PdxT/SNO family family signature. 44 54 - T 23-04-2016 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 DC74_RS09630 6da0ba72c2e973d9fca55a8d196f0404 203 Pfam PF01174 SNO glutamine amidotransferase family 9 193 1.2E-59 T 23-04-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 DC74_RS16175 ea397d6b65f86789a567c6c2316a70a2 354 Gene3D G3DSA:3.40.190.10 140 280 2.8E-27 T 23-04-2016 DC74_RS16175 ea397d6b65f86789a567c6c2316a70a2 354 Pfam PF13343 Bacterial extracellular solute-binding protein 89 340 1.5E-26 T 23-04-2016 DC74_RS16175 ea397d6b65f86789a567c6c2316a70a2 354 PANTHER PTHR30006:SF8 28 298 3.6E-57 T 23-04-2016 DC74_RS16175 ea397d6b65f86789a567c6c2316a70a2 354 SUPERFAMILY SSF53850 36 349 1.05E-55 T 23-04-2016 DC74_RS16175 ea397d6b65f86789a567c6c2316a70a2 354 Gene3D G3DSA:3.40.190.10 9 136 1.3E-35 T 23-04-2016 DC74_RS16175 ea397d6b65f86789a567c6c2316a70a2 354 Gene3D G3DSA:3.40.190.10 281 323 1.3E-35 T 23-04-2016 DC74_RS16175 ea397d6b65f86789a567c6c2316a70a2 354 PANTHER PTHR30006 28 298 3.6E-57 T 23-04-2016 DC74_RS10580 5d81ef3f2b24c972b3f0d1580e143b33 183 ProSitePatterns PS00893 Nudix box signature. 80 101 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS10580 5d81ef3f2b24c972b3f0d1580e143b33 183 SUPERFAMILY SSF55811 17 178 1.35E-31 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS10580 5d81ef3f2b24c972b3f0d1580e143b33 183 Gene3D G3DSA:3.90.79.10 12 178 4.0E-50 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS10580 5d81ef3f2b24c972b3f0d1580e143b33 183 Pfam PF00293 NUDIX domain 43 156 6.6E-14 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS10580 5d81ef3f2b24c972b3f0d1580e143b33 183 PANTHER PTHR22769:SF25 10 170 1.0E-16 T 23-04-2016 DC74_RS10580 5d81ef3f2b24c972b3f0d1580e143b33 183 PIRSF PIRSF017340 8 180 5.3E-72 T 23-04-2016 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 DC74_RS10580 5d81ef3f2b24c972b3f0d1580e143b33 183 PANTHER PTHR22769 10 170 1.0E-16 T 23-04-2016 DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 Pfam PF01037 Lrp/AsnC ligand binding domain 243 311 3.6E-11 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 SUPERFAMILY SSF46785 5 56 2.32E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 Gene3D G3DSA:1.10.10.10 179 224 3.1E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 SUPERFAMILY SSF46785 179 224 5.82E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 23-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 PANTHER PTHR30154 178 320 1.9E-22 T 23-04-2016 DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 SUPERFAMILY SSF54909 239 319 2.28E-11 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 SMART SM00344 5 109 5.0E-4 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 SMART SM00344 179 282 4.6E-11 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 Gene3D G3DSA:3.30.70.920 240 315 1.1E-12 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 Pfam PF13404 AsnC-type helix-turn-helix domain 179 217 8.4E-9 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 Pfam PF13404 AsnC-type helix-turn-helix domain 5 43 3.7E-10 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 Gene3D G3DSA:1.10.10.10 5 53 9.2E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.3E-5 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.3E-5 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS00570 ad748f076909f8dae495018a21f7d7a6 322 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.3E-5 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 SUPERFAMILY SSF52172 2 138 9.68E-33 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 PANTHER PTHR26402:SF151 3 227 2.4E-85 T 23-04-2016 DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 3.3E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 3.3E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 3.3E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 Pfam PF00072 Response regulator receiver domain 5 121 1.8E-24 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 SUPERFAMILY SSF46894 154 227 5.1E-20 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 SMART SM00448 3 120 3.9E-32 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 Gene3D G3DSA:1.10.10.10 128 227 1.7E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 SMART SM00421 164 221 3.3E-21 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 PANTHER PTHR26402 3 227 2.4E-85 T 23-04-2016 DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 221 1.2E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 ProSitePatterns PS00622 LuxR-type HTH domain signature. 181 208 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS37730 0fa5c69f999b74232296a06b7e5b2013 235 Gene3D G3DSA:3.40.50.2300 1 127 3.6E-35 T 23-04-2016 DC74_RS16645 f4f887c861263bc929fd1e926fe8238a 469 PANTHER PTHR23515 387 469 2.1E-206 T 23-04-2016 DC74_RS16645 f4f887c861263bc929fd1e926fe8238a 469 PANTHER PTHR23515 19 368 2.1E-206 T 23-04-2016 DC74_RS16645 f4f887c861263bc929fd1e926fe8238a 469 SUPERFAMILY SSF103473 28 448 7.98E-38 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS16645 f4f887c861263bc929fd1e926fe8238a 469 Pfam PF07690 Major Facilitator Superfamily 58 406 3.7E-16 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS16645 f4f887c861263bc929fd1e926fe8238a 469 PANTHER PTHR23515:SF6 387 469 2.1E-206 T 23-04-2016 DC74_RS16645 f4f887c861263bc929fd1e926fe8238a 469 PANTHER PTHR23515:SF6 19 368 2.1E-206 T 23-04-2016 DC74_RS16645 f4f887c861263bc929fd1e926fe8238a 469 Gene3D G3DSA:1.20.1250.20 51 225 1.3E-10 T 23-04-2016 DC74_RS16645 f4f887c861263bc929fd1e926fe8238a 469 Gene3D G3DSA:1.20.1250.20 245 444 1.1E-12 T 23-04-2016 DC74_RS08465 8f5bab74d908f625010d8ff479de7826 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 388 3.6E-31 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS08465 8f5bab74d908f625010d8ff479de7826 399 Gene3D G3DSA:1.10.540.10 4 119 8.1E-29 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS08465 8f5bab74d908f625010d8ff479de7826 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 1.2E-25 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS08465 8f5bab74d908f625010d8ff479de7826 399 Gene3D G3DSA:1.20.140.10 225 396 3.4E-34 T 23-04-2016 DC74_RS08465 8f5bab74d908f625010d8ff479de7826 399 Gene3D G3DSA:2.40.110.10 122 224 4.4E-30 T 23-04-2016 DC74_RS08465 8f5bab74d908f625010d8ff479de7826 399 PANTHER PTHR10909:SF229 3 399 3.3E-120 T 23-04-2016 DC74_RS08465 8f5bab74d908f625010d8ff479de7826 399 SUPERFAMILY SSF56645 3 248 8.9E-65 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS08465 8f5bab74d908f625010d8ff479de7826 399 SUPERFAMILY SSF47203 235 395 3.87E-27 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS08465 8f5bab74d908f625010d8ff479de7826 399 PANTHER PTHR10909 3 399 3.3E-120 T 23-04-2016 DC74_RS08465 8f5bab74d908f625010d8ff479de7826 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 209 1.7E-18 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS00375 da5465f519451037881612ffdc512268 132 PANTHER PTHR35908 21 128 1.3E-13 T 23-04-2016 DC74_RS00375 da5465f519451037881612ffdc512268 132 SUPERFAMILY SSF54593 20 131 1.61E-15 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS00375 da5465f519451037881612ffdc512268 132 Gene3D G3DSA:3.10.180.10 19 130 2.5E-13 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS29560 ebc7cde3e3a859c62b06541721cfb170 455 Gene3D G3DSA:1.10.260.40 12 73 3.2E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS29560 ebc7cde3e3a859c62b06541721cfb170 455 SUPERFAMILY SSF52540 103 374 6.8E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29560 ebc7cde3e3a859c62b06541721cfb170 455 SUPERFAMILY SSF47413 16 73 1.05E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS29560 ebc7cde3e3a859c62b06541721cfb170 455 SMART SM00530 21 77 1.6E-7 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS29560 ebc7cde3e3a859c62b06541721cfb170 455 Gene3D G3DSA:3.40.50.300 368 413 1.5E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29560 ebc7cde3e3a859c62b06541721cfb170 455 Gene3D G3DSA:3.40.50.300 122 173 1.5E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29560 ebc7cde3e3a859c62b06541721cfb170 455 Pfam PF13560 Helix-turn-helix domain 26 75 1.0E-8 T 23-04-2016 DC74_RS29560 ebc7cde3e3a859c62b06541721cfb170 455 PRINTS PR00364 Disease resistance protein signature 137 152 6.2E-5 T 23-04-2016 DC74_RS29560 ebc7cde3e3a859c62b06541721cfb170 455 PRINTS PR00364 Disease resistance protein signature 309 323 6.2E-5 T 23-04-2016 DC74_RS25135 fffeb216f6588566df2b08a73f84ed92 294 SUPERFAMILY SSF55681 36 220 4.35E-44 T 23-04-2016 DC74_RS25135 fffeb216f6588566df2b08a73f84ed92 294 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 45 284 2.2E-36 T 23-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 DC74_RS25135 fffeb216f6588566df2b08a73f84ed92 294 Pfam PF03099 Biotin/lipoate A/B protein ligase family 47 171 6.0E-5 T 23-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 DC74_RS25135 fffeb216f6588566df2b08a73f84ed92 294 PANTHER PTHR12835 16 286 2.6E-55 T 23-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 DC74_RS25135 fffeb216f6588566df2b08a73f84ed92 294 Gene3D G3DSA:2.30.30.100 238 282 1.1E-5 T 23-04-2016 DC74_RS25135 fffeb216f6588566df2b08a73f84ed92 294 Gene3D G3DSA:3.30.930.10 34 221 6.3E-51 T 23-04-2016 DC74_RS25135 fffeb216f6588566df2b08a73f84ed92 294 Pfam PF02237 Biotin protein ligase C terminal domain 237 284 1.3E-12 T 23-04-2016 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15 DC74_RS26570 8e4e7824975d7ec9e3ab11940f28835b 427 PANTHER PTHR23523:SF2 24 425 5.4E-147 T 23-04-2016 DC74_RS26570 8e4e7824975d7ec9e3ab11940f28835b 427 PANTHER PTHR23523 24 425 5.4E-147 T 23-04-2016 DC74_RS26570 8e4e7824975d7ec9e3ab11940f28835b 427 Pfam PF07690 Major Facilitator Superfamily 61 380 4.7E-20 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS26570 8e4e7824975d7ec9e3ab11940f28835b 427 Gene3D G3DSA:1.20.1250.20 234 409 1.7E-16 T 23-04-2016 DC74_RS26570 8e4e7824975d7ec9e3ab11940f28835b 427 Gene3D G3DSA:1.20.1250.20 58 222 4.2E-14 T 23-04-2016 DC74_RS26570 8e4e7824975d7ec9e3ab11940f28835b 427 SUPERFAMILY SSF103473 29 414 8.5E-48 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS23620 88c37f1e41cb4a38c2a91c07c76e94b4 240 SUPERFAMILY SSF110395 6 233 3.92E-43 T 23-04-2016 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 DC74_RS23620 88c37f1e41cb4a38c2a91c07c76e94b4 240 PANTHER PTHR12598 1 213 1.4E-47 T 23-04-2016 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 DC74_RS23620 88c37f1e41cb4a38c2a91c07c76e94b4 240 Pfam PF03932 CutC family 6 207 2.0E-25 T 23-04-2016 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 DC74_RS23620 88c37f1e41cb4a38c2a91c07c76e94b4 240 Gene3D G3DSA:3.20.20.380 5 233 3.0E-49 T 23-04-2016 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 DC74_RS23620 88c37f1e41cb4a38c2a91c07c76e94b4 240 PANTHER PTHR12598:SF0 1 213 1.4E-47 T 23-04-2016 DC74_RS22700 097c677a562b9715e89ac9be5be24270 374 Pfam PF10635 DisA bacterial checkpoint controller linker region 155 296 4.6E-51 T 23-04-2016 IPR018906 DNA integrity scanning, DisA, linker region DC74_RS22700 097c677a562b9715e89ac9be5be24270 374 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 16 371 43.493 T 23-04-2016 IPR023763 DNA integrity scanning protein, DisA DC74_RS22700 097c677a562b9715e89ac9be5be24270 374 Pfam PF12826 Helix-hairpin-helix motif 324 361 1.5E-6 T 23-04-2016 DC74_RS22700 097c677a562b9715e89ac9be5be24270 374 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 38 151 5.3E-23 T 23-04-2016 IPR003390 DNA integrity scanning protein, DisA, N-terminal DC74_RS22700 097c677a562b9715e89ac9be5be24270 374 Gene3D G3DSA:1.10.150.20 313 361 1.7E-11 T 23-04-2016 DC74_RS22700 097c677a562b9715e89ac9be5be24270 374 SUPERFAMILY SSF47781 297 366 4.82E-12 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 DC74_RS22700 097c677a562b9715e89ac9be5be24270 374 SUPERFAMILY SSF143597 31 153 7.85E-27 T 23-04-2016 DC74_RS22700 097c677a562b9715e89ac9be5be24270 374 Gene3D G3DSA:3.40.1700.10 31 154 6.6E-30 T 23-04-2016 DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 PANTHER PTHR24322 149 181 1.1E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 PANTHER PTHR24322 8 133 1.1E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 251 5.0E-59 T 23-04-2016 DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.6E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.6E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.6E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.6E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.6E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.6E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 SUPERFAMILY SSF51735 3 251 5.48E-74 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 184 3.8E-5 T 23-04-2016 DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.5E-13 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.5E-13 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.5E-13 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22860 cbbecb0fa92aae9ead4d492cd2285058 254 Gene3D G3DSA:3.40.50.720 1 251 2.7E-78 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19120 5fed3595af098568cbc6d5161ddf1043 338 Pfam PF00756 Putative esterase 89 302 1.9E-16 T 23-04-2016 IPR000801 Putative esterase DC74_RS19120 5fed3595af098568cbc6d5161ddf1043 338 Gene3D G3DSA:3.40.50.1820 56 311 2.4E-35 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS19120 5fed3595af098568cbc6d5161ddf1043 338 PANTHER PTHR10907:SF33 78 234 6.7E-16 T 23-04-2016 DC74_RS19120 5fed3595af098568cbc6d5161ddf1043 338 PANTHER PTHR10907 78 234 6.7E-16 T 23-04-2016 DC74_RS19120 5fed3595af098568cbc6d5161ddf1043 338 SUPERFAMILY SSF53474 76 312 1.09E-30 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS30140 a66b04045d538c008d1999ae69976d94 297 PANTHER PTHR35149:SF1 14 296 8.8E-99 T 23-04-2016 DC74_RS30140 a66b04045d538c008d1999ae69976d94 297 PANTHER PTHR35149 14 296 8.8E-99 T 23-04-2016 DC74_RS21595 32cdd7c65ce0e35ecee982d30e84e207 97 SUPERFAMILY SSF54909 2 94 3.35E-16 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS21595 32cdd7c65ce0e35ecee982d30e84e207 97 Pfam PF07876 Stress responsive A/B Barrel Domain 2 96 1.8E-20 T 23-04-2016 IPR013097 Stress responsive alpha-beta barrel DC74_RS21595 32cdd7c65ce0e35ecee982d30e84e207 97 PANTHER PTHR37832 1 97 2.0E-22 T 23-04-2016 DC74_RS21595 32cdd7c65ce0e35ecee982d30e84e207 97 SMART SM00886 2 97 2.1E-23 T 23-04-2016 IPR013097 Stress responsive alpha-beta barrel DC74_RS21595 32cdd7c65ce0e35ecee982d30e84e207 97 Gene3D G3DSA:3.30.70.900 1 96 3.0E-24 T 23-04-2016 DC74_RS21595 32cdd7c65ce0e35ecee982d30e84e207 97 PANTHER PTHR37832:SF1 1 97 2.0E-22 T 23-04-2016 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 PRINTS PR00046 Major sigma-70 factor signature 75 88 5.6E-12 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 PRINTS PR00046 Major sigma-70 factor signature 243 258 5.6E-12 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 PRINTS PR00046 Major sigma-70 factor signature 258 269 5.6E-12 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 PRINTS PR00046 Major sigma-70 factor signature 226 238 5.6E-12 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 PIRSF PIRSF000770 27 277 5.5E-75 T 23-04-2016 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 75 88 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 SUPERFAMILY SSF88946 19 120 1.16E-25 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 48 273 2.7E-87 T 23-04-2016 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 Pfam PF04539 Sigma-70 region 3 128 208 3.7E-7 T 23-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 SUPERFAMILY SSF88659 187 275 3.36E-24 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 Gene3D G3DSA:1.10.601.10 23 111 2.3E-16 T 23-04-2016 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 243 269 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 Pfam PF04545 Sigma-70, region 4 222 271 1.2E-18 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 PANTHER PTHR30385:SF7 10 274 1.4E-82 T 23-04-2016 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 Gene3D G3DSA:1.10.10.10 211 275 6.6E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 PANTHER PTHR30385 10 274 1.4E-82 T 23-04-2016 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 Pfam PF04542 Sigma-70 region 2 48 120 4.6E-16 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 Gene3D G3DSA:1.10.10.10 120 163 6.2E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 SUPERFAMILY SSF88659 121 200 1.05E-13 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS28180 56b01cd1f55250529cd677bb124cf258 278 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 44 273 2.5E-36 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 Gene3D G3DSA:1.10.10.10 126 220 1.5E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.7E-21 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 PANTHER PTHR26402:SF564 3 219 7.5E-130 T 23-04-2016 DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 Pfam PF00072 Response regulator receiver domain 5 119 9.0E-29 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 SUPERFAMILY SSF46894 148 218 3.74E-23 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 SMART SM00448 3 118 1.0E-36 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 Gene3D G3DSA:3.40.50.2300 3 125 1.6E-39 T 23-04-2016 DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 3.0E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 3.0E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 3.0E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 SMART SM00421 155 212 2.1E-28 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 SUPERFAMILY SSF52172 3 137 1.31E-35 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS10360 2271e7c3054e8cf80876eef39757265d 223 PANTHER PTHR26402 3 219 7.5E-130 T 23-04-2016 DC74_RS01550 a5a6e2593628a2eb2c3352cc2f32caee 335 PANTHER PTHR21240:SF7 6 323 1.1E-73 T 23-04-2016 DC74_RS01550 a5a6e2593628a2eb2c3352cc2f32caee 335 Pfam PF04909 Amidohydrolase 7 312 8.1E-39 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS01550 a5a6e2593628a2eb2c3352cc2f32caee 335 SUPERFAMILY SSF51556 6 312 9.62E-75 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS01550 a5a6e2593628a2eb2c3352cc2f32caee 335 Gene3D G3DSA:3.20.20.140 6 313 5.2E-100 T 23-04-2016 DC74_RS01550 a5a6e2593628a2eb2c3352cc2f32caee 335 PANTHER PTHR21240 6 323 1.1E-73 T 23-04-2016 DC74_RS11520 a060bfa601c858af15ad67892d533769 719 Pfam PF13519 von Willebrand factor type A domain 519 625 1.2E-14 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS11520 a060bfa601c858af15ad67892d533769 719 Gene3D G3DSA:3.40.50.300 9 207 9.3E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11520 a060bfa601c858af15ad67892d533769 719 SUPERFAMILY SSF53300 519 682 4.15E-22 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS11520 a060bfa601c858af15ad67892d533769 719 Gene3D G3DSA:3.40.50.410 519 649 2.6E-13 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS11520 a060bfa601c858af15ad67892d533769 719 SMART SM00327 516 693 7.7E-18 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS11520 a060bfa601c858af15ad67892d533769 719 TIGRFAM TIGR02442 Cob-chelat-sub: cobaltochelatase subunit 11 681 2.1E-250 T 23-04-2016 IPR012804 Cobaltochelatase subunit, putative DC74_RS11520 a060bfa601c858af15ad67892d533769 719 Pfam PF01078 Magnesium chelatase, subunit ChlI 119 188 3.0E-7 T 23-04-2016 IPR000523 Magnesium chelatase ChlI domain DC74_RS11520 a060bfa601c858af15ad67892d533769 719 SUPERFAMILY SSF52540 9 334 2.4E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11520 a060bfa601c858af15ad67892d533769 719 PANTHER PTHR35023:SF1 3 369 7.3E-139 T 23-04-2016 DC74_RS11520 a060bfa601c858af15ad67892d533769 719 PANTHER PTHR35023:SF1 454 686 7.3E-139 T 23-04-2016 DC74_RS11520 a060bfa601c858af15ad67892d533769 719 Gene3D G3DSA:1.10.8.80 253 340 1.2E-33 T 23-04-2016 DC74_RS11520 a060bfa601c858af15ad67892d533769 719 SMART SM00382 34 464 0.001 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS11520 a060bfa601c858af15ad67892d533769 719 PANTHER PTHR35023 3 369 7.3E-139 T 23-04-2016 DC74_RS11520 a060bfa601c858af15ad67892d533769 719 PANTHER PTHR35023 454 686 7.3E-139 T 23-04-2016 DC74_RS08440 bfaebb38b5339e73c3642bcd43d14a52 367 Gene3D G3DSA:3.20.20.70 106 345 8.0E-51 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS08440 bfaebb38b5339e73c3642bcd43d14a52 367 Gene3D G3DSA:3.20.20.70 3 71 8.0E-51 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS08440 bfaebb38b5339e73c3642bcd43d14a52 367 PANTHER PTHR10982 1 112 4.4E-96 T 23-04-2016 DC74_RS08440 bfaebb38b5339e73c3642bcd43d14a52 367 PANTHER PTHR10982 143 363 4.4E-96 T 23-04-2016 DC74_RS08440 bfaebb38b5339e73c3642bcd43d14a52 367 PANTHER PTHR10982:SF10 1 112 4.4E-96 T 23-04-2016 DC74_RS08440 bfaebb38b5339e73c3642bcd43d14a52 367 PANTHER PTHR10982:SF10 143 363 4.4E-96 T 23-04-2016 DC74_RS08440 bfaebb38b5339e73c3642bcd43d14a52 367 SUPERFAMILY SSF51412 93 309 2.44E-41 T 23-04-2016 DC74_RS08440 bfaebb38b5339e73c3642bcd43d14a52 367 SUPERFAMILY SSF51412 22 58 2.44E-41 T 23-04-2016 DC74_RS08440 bfaebb38b5339e73c3642bcd43d14a52 367 Pfam PF03060 Nitronate monooxygenase 16 350 2.0E-43 T 23-04-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 DC74_RS38300 1532bf3b435bf3a59d21c53e4a5222d0 283 SUPERFAMILY SSF53850 30 262 8.69E-72 T 23-04-2016 DC74_RS38300 1532bf3b435bf3a59d21c53e4a5222d0 283 Pfam PF03180 NLPA lipoprotein 27 259 5.7E-75 T 23-04-2016 IPR004872 Lipoprotein NlpA family DC74_RS38300 1532bf3b435bf3a59d21c53e4a5222d0 283 Gene3D G3DSA:3.40.190.10 24 151 3.9E-46 T 23-04-2016 DC74_RS38300 1532bf3b435bf3a59d21c53e4a5222d0 283 PANTHER PTHR30429:SF1 1 263 1.6E-93 T 23-04-2016 DC74_RS38300 1532bf3b435bf3a59d21c53e4a5222d0 283 PIRSF PIRSF002854 1 262 9.9E-79 T 23-04-2016 IPR004872 Lipoprotein NlpA family DC74_RS38300 1532bf3b435bf3a59d21c53e4a5222d0 283 PANTHER PTHR30429 1 263 1.6E-93 T 23-04-2016 IPR004872 Lipoprotein NlpA family DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 PANTHER PTHR24567 1 224 1.9E-66 T 23-04-2016 DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 78 95 - T 23-04-2016 IPR018488 Cyclic nucleotide-binding, conserved site DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 4.3E-17 T 23-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 Gene3D G3DSA:1.10.10.10 145 222 6.5E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 110 5.1E-26 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 SMART SM00100 10 128 6.3E-27 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 SMART SM00419 167 215 2.1E-13 T 23-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 SUPERFAMILY SSF51206 3 142 1.83E-39 T 23-04-2016 IPR018490 Cyclic nucleotide-binding-like DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 Gene3D G3DSA:2.60.120.10 2 143 6.1E-41 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 PRINTS PR00103 cAMP-dependent protein kinase signature 31 45 2.4E-6 T 23-04-2016 DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 PRINTS PR00103 cAMP-dependent protein kinase signature 46 60 2.4E-6 T 23-04-2016 DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 PRINTS PR00103 cAMP-dependent protein kinase signature 76 85 2.4E-6 T 23-04-2016 DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 PRINTS PR00103 cAMP-dependent protein kinase signature 88 99 2.4E-6 T 23-04-2016 DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 SUPERFAMILY SSF46785 145 222 2.93E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22050 06b1f5f98545c718b389fd51503bb82f 224 PANTHER PTHR24567:SF30 1 224 1.9E-66 T 23-04-2016 DC74_RS21430 5a0b2871324c40a6ca671b76cc2cab21 313 SMART SM00342 223 305 3.6E-22 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS21430 5a0b2871324c40a6ca671b76cc2cab21 313 SUPERFAMILY SSF52317 1 188 5.67E-50 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS21430 5a0b2871324c40a6ca671b76cc2cab21 313 PANTHER PTHR11019 64 313 1.1E-78 T 23-04-2016 DC74_RS21430 5a0b2871324c40a6ca671b76cc2cab21 313 Pfam PF12833 Helix-turn-helix domain 229 307 6.0E-20 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS21430 5a0b2871324c40a6ca671b76cc2cab21 313 SUPERFAMILY SSF46689 206 256 2.51E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS21430 5a0b2871324c40a6ca671b76cc2cab21 313 SUPERFAMILY SSF46689 259 309 9.86E-6 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS21430 5a0b2871324c40a6ca671b76cc2cab21 313 Gene3D G3DSA:1.10.10.60 212 262 9.4E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS21430 5a0b2871324c40a6ca671b76cc2cab21 313 Gene3D G3DSA:3.40.50.880 1 211 3.8E-57 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS21430 5a0b2871324c40a6ca671b76cc2cab21 313 Gene3D G3DSA:1.10.10.60 263 309 2.1E-6 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS21430 5a0b2871324c40a6ca671b76cc2cab21 313 PANTHER PTHR11019:SF58 64 313 1.1E-78 T 23-04-2016 DC74_RS21430 5a0b2871324c40a6ca671b76cc2cab21 313 Pfam PF01965 DJ-1/PfpI family 2 167 5.7E-27 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS07285 f7f7988278d18351a7e95eba29e68aee 415 PANTHER PTHR23534 7 409 4.1E-79 T 23-04-2016 DC74_RS07285 f7f7988278d18351a7e95eba29e68aee 415 Pfam PF07690 Major Facilitator Superfamily 242 402 2.3E-15 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS07285 f7f7988278d18351a7e95eba29e68aee 415 Gene3D G3DSA:1.20.1250.20 231 404 3.9E-20 T 23-04-2016 DC74_RS07285 f7f7988278d18351a7e95eba29e68aee 415 Gene3D G3DSA:1.20.1250.20 8 195 1.1E-14 T 23-04-2016 DC74_RS07285 f7f7988278d18351a7e95eba29e68aee 415 SUPERFAMILY SSF103473 6 406 1.31E-42 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS09785 28f11fcaa35f8826b34ae5094f65a3e2 452 SUPERFAMILY SSF56112 13 259 2.66E-62 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS09785 28f11fcaa35f8826b34ae5094f65a3e2 452 Gene3D G3DSA:3.30.200.20 7 113 7.1E-17 T 23-04-2016 DC74_RS09785 28f11fcaa35f8826b34ae5094f65a3e2 452 PANTHER PTHR24362 1 398 2.8E-86 T 23-04-2016 DC74_RS09785 28f11fcaa35f8826b34ae5094f65a3e2 452 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 23 45 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS09785 28f11fcaa35f8826b34ae5094f65a3e2 452 SMART SM00220 17 269 3.0E-47 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS09785 28f11fcaa35f8826b34ae5094f65a3e2 452 Pfam PF00069 Protein kinase domain 18 259 2.8E-40 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS09785 28f11fcaa35f8826b34ae5094f65a3e2 452 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS09785 28f11fcaa35f8826b34ae5094f65a3e2 452 PANTHER PTHR24362:SF160 1 398 2.8E-86 T 23-04-2016 DC74_RS09785 28f11fcaa35f8826b34ae5094f65a3e2 452 Gene3D G3DSA:1.10.510.10 114 332 1.2E-38 T 23-04-2016 DC74_RS27555 dedb1120871b30bceaeffe48c38496f6 180 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 159 1.3E-35 T 23-04-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG DC74_RS27555 dedb1120871b30bceaeffe48c38496f6 180 Gene3D G3DSA:3.40.50.450 1 179 5.2E-46 T 23-04-2016 DC74_RS27555 dedb1120871b30bceaeffe48c38496f6 180 PANTHER PTHR31223:SF0 2 178 2.4E-58 T 23-04-2016 DC74_RS27555 dedb1120871b30bceaeffe48c38496f6 180 Pfam PF03641 Possible lysine decarboxylase 44 171 7.6E-30 T 23-04-2016 IPR031100 LOG family DC74_RS27555 dedb1120871b30bceaeffe48c38496f6 180 SUPERFAMILY SSF102405 1 174 1.07E-43 T 23-04-2016 DC74_RS27555 dedb1120871b30bceaeffe48c38496f6 180 PANTHER PTHR31223 2 178 2.4E-58 T 23-04-2016 DC74_RS02130 afc1e3803f0258b92ac2de9fdec782ad 323 SUPERFAMILY SSF52317 4 195 1.11E-51 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS02130 afc1e3803f0258b92ac2de9fdec782ad 323 Gene3D G3DSA:1.10.10.60 218 268 8.4E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02130 afc1e3803f0258b92ac2de9fdec782ad 323 PANTHER PTHR11019:SF58 71 321 8.2E-86 T 23-04-2016 DC74_RS02130 afc1e3803f0258b92ac2de9fdec782ad 323 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 217 259 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS02130 afc1e3803f0258b92ac2de9fdec782ad 323 SUPERFAMILY SSF46689 215 263 2.87E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02130 afc1e3803f0258b92ac2de9fdec782ad 323 Gene3D G3DSA:3.40.50.880 5 217 2.7E-60 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS02130 afc1e3803f0258b92ac2de9fdec782ad 323 PANTHER PTHR11019 71 321 8.2E-86 T 23-04-2016 DC74_RS02130 afc1e3803f0258b92ac2de9fdec782ad 323 SMART SM00342 230 313 1.4E-29 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS02130 afc1e3803f0258b92ac2de9fdec782ad 323 Pfam PF01965 DJ-1/PfpI family 4 174 4.0E-27 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS02130 afc1e3803f0258b92ac2de9fdec782ad 323 SUPERFAMILY SSF46689 266 317 4.18E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02130 afc1e3803f0258b92ac2de9fdec782ad 323 Gene3D G3DSA:1.10.10.60 269 318 1.1E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02130 afc1e3803f0258b92ac2de9fdec782ad 323 Pfam PF12833 Helix-turn-helix domain 236 315 7.7E-25 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS36215 4f496888e31072a24edc327881a4118b 235 Pfam PF16715 Cyclodipeptide synthase 14 204 3.1E-33 T 23-04-2016 IPR030903 Cyclodileucine synthase GO:0016755 DC74_RS36215 4f496888e31072a24edc327881a4118b 235 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 15 200 1.0E-16 T 23-04-2016 IPR030903 Cyclodileucine synthase GO:0016755 DC74_RS06360 69d34346db20097006a982f7208620dc 396 PANTHER PTHR23514 10 384 4.7E-115 T 23-04-2016 DC74_RS06360 69d34346db20097006a982f7208620dc 396 PANTHER PTHR23514:SF13 10 384 4.7E-115 T 23-04-2016 DC74_RS06360 69d34346db20097006a982f7208620dc 396 Pfam PF07690 Major Facilitator Superfamily 18 323 2.0E-23 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS06360 69d34346db20097006a982f7208620dc 396 Gene3D G3DSA:1.20.1250.20 14 182 7.4E-20 T 23-04-2016 DC74_RS06360 69d34346db20097006a982f7208620dc 396 Gene3D G3DSA:1.20.1250.20 209 384 8.5E-13 T 23-04-2016 DC74_RS06360 69d34346db20097006a982f7208620dc 396 SUPERFAMILY SSF103473 10 384 2.35E-38 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS22840 11fa65da4971bedea152430afde72b2e 425 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 380 1.3E-35 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS22840 11fa65da4971bedea152430afde72b2e 425 Gene3D G3DSA:3.40.47.10 2 266 4.2E-48 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22840 11fa65da4971bedea152430afde72b2e 425 Gene3D G3DSA:3.40.47.10 273 424 7.1E-58 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22840 11fa65da4971bedea152430afde72b2e 425 PANTHER PTHR11712 3 117 3.9E-117 T 23-04-2016 DC74_RS22840 11fa65da4971bedea152430afde72b2e 425 PANTHER PTHR11712 136 424 3.9E-117 T 23-04-2016 DC74_RS22840 11fa65da4971bedea152430afde72b2e 425 SUPERFAMILY SSF53901 3 261 1.73E-51 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22840 11fa65da4971bedea152430afde72b2e 425 SUPERFAMILY SSF53901 226 423 5.4E-67 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22840 11fa65da4971bedea152430afde72b2e 425 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 256 7.8E-36 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS22840 11fa65da4971bedea152430afde72b2e 425 SMART SM00825 Beta-ketoacyl synthase 5 425 1.5E-15 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS08825 3b9d639f4f8ce18df4245d0b7e74c848 404 Gene3D G3DSA:3.30.420.40 232 379 1.4E-31 T 23-04-2016 DC74_RS08825 3b9d639f4f8ce18df4245d0b7e74c848 404 PANTHER PTHR18964:SF108 63 404 2.3E-81 T 23-04-2016 DC74_RS08825 3b9d639f4f8ce18df4245d0b7e74c848 404 PANTHER PTHR18964 63 404 2.3E-81 T 23-04-2016 DC74_RS08825 3b9d639f4f8ce18df4245d0b7e74c848 404 Gene3D G3DSA:1.10.10.10 20 81 1.7E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08825 3b9d639f4f8ce18df4245d0b7e74c848 404 SUPERFAMILY SSF53067 228 401 1.48E-30 T 23-04-2016 DC74_RS08825 3b9d639f4f8ce18df4245d0b7e74c848 404 Gene3D G3DSA:3.30.420.40 82 231 3.1E-21 T 23-04-2016 DC74_RS08825 3b9d639f4f8ce18df4245d0b7e74c848 404 SUPERFAMILY SSF53067 87 218 2.72E-11 T 23-04-2016 DC74_RS08825 3b9d639f4f8ce18df4245d0b7e74c848 404 Pfam PF00480 ROK family 121 392 7.4E-29 T 23-04-2016 IPR000600 ROK family DC74_RS29420 3fc5cc60c48d06b6fff2c3d361edff08 302 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 153 280 1.0E-37 T 23-04-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 DC74_RS29420 3fc5cc60c48d06b6fff2c3d361edff08 302 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 1 281 9.9E-111 T 23-04-2016 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|UniPathway: UPA00362 DC74_RS29420 3fc5cc60c48d06b6fff2c3d361edff08 302 PIRSF PIRSF000103 1 288 9.5E-69 T 23-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 DC74_RS29420 3fc5cc60c48d06b6fff2c3d361edff08 302 SUPERFAMILY SSF51735 1 151 2.52E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29420 3fc5cc60c48d06b6fff2c3d361edff08 302 Gene3D G3DSA:1.10.1040.10 152 282 3.4E-43 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS29420 3fc5cc60c48d06b6fff2c3d361edff08 302 SUPERFAMILY SSF48179 152 281 5.1E-38 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS29420 3fc5cc60c48d06b6fff2c3d361edff08 302 PANTHER PTHR22981 2 281 1.1E-100 T 23-04-2016 DC74_RS29420 3fc5cc60c48d06b6fff2c3d361edff08 302 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 1 150 1.1E-40 T 23-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 DC74_RS29420 3fc5cc60c48d06b6fff2c3d361edff08 302 Gene3D G3DSA:3.40.50.720 1 151 3.3E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS13250 6d1d6d0d39e9d13d54b196467c43a1b5 424 PANTHER PTHR30061 1 423 9.5E-82 T 23-04-2016 DC74_RS13250 6d1d6d0d39e9d13d54b196467c43a1b5 424 Gene3D G3DSA:3.40.190.10 42 170 1.6E-23 T 23-04-2016 DC74_RS13250 6d1d6d0d39e9d13d54b196467c43a1b5 424 SUPERFAMILY SSF53850 41 411 1.93E-85 T 23-04-2016 DC74_RS13250 6d1d6d0d39e9d13d54b196467c43a1b5 424 Pfam PF13416 Bacterial extracellular solute-binding protein 58 363 2.7E-46 T 23-04-2016 DC74_RS13250 6d1d6d0d39e9d13d54b196467c43a1b5 424 Gene3D G3DSA:3.40.190.10 171 350 2.3E-42 T 23-04-2016 DC74_RS09025 5e561166b09030d5affee8028964f561 256 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 62 3.4E-19 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS09025 5e561166b09030d5affee8028964f561 256 SUPERFAMILY SSF46689 7 91 9.98E-22 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS09025 5e561166b09030d5affee8028964f561 256 PANTHER PTHR30055 2 241 1.3E-103 T 23-04-2016 DC74_RS09025 5e561166b09030d5affee8028964f561 256 PANTHER PTHR30055:SF24 2 241 1.3E-103 T 23-04-2016 DC74_RS09025 5e561166b09030d5affee8028964f561 256 SUPERFAMILY SSF48498 86 227 3.56E-48 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS09025 5e561166b09030d5affee8028964f561 256 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 6.2E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS09025 5e561166b09030d5affee8028964f561 256 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 6.2E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS09025 5e561166b09030d5affee8028964f561 256 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS09025 5e561166b09030d5affee8028964f561 256 Gene3D G3DSA:1.10.357.10 11 202 8.3E-37 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS22805 172954bccafc125a2655904dec621fae 214 SUPERFAMILY SSF46689 13 83 2.15E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS22805 172954bccafc125a2655904dec621fae 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 5.8E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS22805 172954bccafc125a2655904dec621fae 214 Pfam PF13977 Bacterial transcriptional repressor 114 188 8.0E-10 T 23-04-2016 DC74_RS22805 172954bccafc125a2655904dec621fae 214 Gene3D G3DSA:1.10.357.10 13 190 4.3E-29 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS22805 172954bccafc125a2655904dec621fae 214 SUPERFAMILY SSF48498 116 189 2.54E-8 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS22805 172954bccafc125a2655904dec621fae 214 PANTHER PTHR30055 9 213 2.0E-16 T 23-04-2016 DC74_RS17940 ad1bba4e6de15448e8be95a6055adabe 393 Pfam PF03576 Peptidase family S58 24 363 1.4E-69 T 23-04-2016 IPR005321 Peptidase S58, DmpA DC74_RS17940 ad1bba4e6de15448e8be95a6055adabe 393 PANTHER PTHR36512 6 383 1.0E-135 T 23-04-2016 DC74_RS17940 ad1bba4e6de15448e8be95a6055adabe 393 Gene3D G3DSA:3.60.70.12 15 366 1.1E-89 T 23-04-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS17940 ad1bba4e6de15448e8be95a6055adabe 393 PANTHER PTHR36512:SF3 6 383 1.0E-135 T 23-04-2016 DC74_RS17940 ad1bba4e6de15448e8be95a6055adabe 393 SUPERFAMILY SSF56266 15 363 2.88E-71 T 23-04-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS38850 d2fb3e20aae06a7ca249b1f6f5868de8 342 PANTHER PTHR11746:SF63 1 325 5.2E-65 T 23-04-2016 DC74_RS38850 d2fb3e20aae06a7ca249b1f6f5868de8 342 PIRSF PIRSF005739 2 336 1.8E-28 T 23-04-2016 IPR016461 O-methyltransferase COMT-type GO:0008168 DC74_RS38850 d2fb3e20aae06a7ca249b1f6f5868de8 342 Gene3D G3DSA:1.10.10.10 7 87 6.3E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38850 d2fb3e20aae06a7ca249b1f6f5868de8 342 SUPERFAMILY SSF53335 96 332 1.19E-46 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS38850 d2fb3e20aae06a7ca249b1f6f5868de8 342 Gene3D G3DSA:3.40.50.150 93 340 1.1E-59 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS38850 d2fb3e20aae06a7ca249b1f6f5868de8 342 Pfam PF16864 Dimerisation domain 13 95 2.5E-15 T 23-04-2016 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain DC74_RS38850 d2fb3e20aae06a7ca249b1f6f5868de8 342 PANTHER PTHR11746 1 325 5.2E-65 T 23-04-2016 DC74_RS38850 d2fb3e20aae06a7ca249b1f6f5868de8 342 Pfam PF00891 O-methyltransferase 104 326 4.3E-45 T 23-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 DC74_RS38850 d2fb3e20aae06a7ca249b1f6f5868de8 342 SUPERFAMILY SSF46785 11 87 4.47E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17220 7d169b49dbf0efbd5d535cef77725900 412 PANTHER PTHR32494 2 410 3.0E-128 T 23-04-2016 DC74_RS17220 7d169b49dbf0efbd5d535cef77725900 412 PANTHER PTHR32494:SF5 2 410 3.0E-128 T 23-04-2016 DC74_RS17220 7d169b49dbf0efbd5d535cef77725900 412 SUPERFAMILY SSF53187 7 225 8.91E-68 T 23-04-2016 DC74_RS17220 7d169b49dbf0efbd5d535cef77725900 412 SUPERFAMILY SSF53187 336 410 8.91E-68 T 23-04-2016 DC74_RS17220 7d169b49dbf0efbd5d535cef77725900 412 PIRSF PIRSF001235 1 412 5.9E-121 T 23-04-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 DC74_RS17220 7d169b49dbf0efbd5d535cef77725900 412 Gene3D G3DSA:3.40.630.10 5 228 2.2E-89 T 23-04-2016 DC74_RS17220 7d169b49dbf0efbd5d535cef77725900 412 Gene3D G3DSA:3.40.630.10 352 410 2.2E-89 T 23-04-2016 DC74_RS17220 7d169b49dbf0efbd5d535cef77725900 412 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 9 405 2.7E-83 T 23-04-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 DC74_RS17220 7d169b49dbf0efbd5d535cef77725900 412 Gene3D G3DSA:3.30.70.360 229 329 2.7E-27 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS17220 7d169b49dbf0efbd5d535cef77725900 412 Pfam PF01546 Peptidase family M20/M25/M40 79 407 6.6E-24 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS17220 7d169b49dbf0efbd5d535cef77725900 412 SUPERFAMILY SSF55031 218 327 2.09E-18 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 Pfam PF13541 Subunit ChlI of Mg-chelatase 371 430 3.6E-8 T 23-04-2016 DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 SUPERFAMILY SSF52540 71 294 2.71E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 Pfam PF13481 AAA domain 78 223 1.2E-14 T 23-04-2016 DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 SMART SM00382 91 245 1.3E-8 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 PANTHER PTHR32472 5 467 2.9E-183 T 23-04-2016 DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 PRINTS PR01874 DNA repair protein radA signature 214 242 1.6E-85 T 23-04-2016 DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 PRINTS PR01874 DNA repair protein radA signature 249 275 1.6E-85 T 23-04-2016 DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 PRINTS PR01874 DNA repair protein radA signature 83 111 1.6E-85 T 23-04-2016 DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 PRINTS PR01874 DNA repair protein radA signature 125 142 1.6E-85 T 23-04-2016 DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 PRINTS PR01874 DNA repair protein radA signature 323 346 1.6E-85 T 23-04-2016 DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 PRINTS PR01874 DNA repair protein radA signature 16 40 1.6E-85 T 23-04-2016 DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 PRINTS PR01874 DNA repair protein radA signature 175 199 1.6E-85 T 23-04-2016 DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 Gene3D G3DSA:3.30.230.10 285 454 1.3E-30 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 PANTHER PTHR32472:SF10 5 467 2.9E-183 T 23-04-2016 DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 Gene3D G3DSA:3.40.50.300 66 276 5.6E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 SUPERFAMILY SSF54211 294 454 9.86E-34 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS22705 edd8fbd56f49dd79275a7609e4a12d89 470 TIGRFAM TIGR00416 sms: DNA repair protein RadA 8 451 1.1E-152 T 23-04-2016 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 DC74_RS37760 8e1b479a6a55914ad176d0ebd5e91ddc 253 Gene3D G3DSA:3.20.20.410 1 237 1.3E-73 T 23-04-2016 IPR002763 Protein of unknown function DUF72 DC74_RS37760 8e1b479a6a55914ad176d0ebd5e91ddc 253 Pfam PF01904 Protein of unknown function DUF72 20 237 5.6E-58 T 23-04-2016 IPR002763 Protein of unknown function DUF72 DC74_RS37760 8e1b479a6a55914ad176d0ebd5e91ddc 253 SUPERFAMILY SSF117396 1 237 1.03E-73 T 23-04-2016 IPR002763 Protein of unknown function DUF72 DC74_RS37760 8e1b479a6a55914ad176d0ebd5e91ddc 253 PANTHER PTHR30348 1 237 2.2E-69 T 23-04-2016 DC74_RS39470 e78f04cebc5aeea60d4605879cb2c7fe 305 PANTHER PTHR11177 19 200 1.9E-14 T 23-04-2016 DC74_RS39470 e78f04cebc5aeea60d4605879cb2c7fe 305 Pfam PF00704 Glycosyl hydrolases family 18 71 214 1.5E-15 T 23-04-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 DC74_RS39470 e78f04cebc5aeea60d4605879cb2c7fe 305 PANTHER PTHR11177:SF203 19 200 1.9E-14 T 23-04-2016 DC74_RS39470 e78f04cebc5aeea60d4605879cb2c7fe 305 Gene3D G3DSA:3.20.20.80 40 303 5.4E-68 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS39470 e78f04cebc5aeea60d4605879cb2c7fe 305 ProSitePatterns PS01095 Chitinases family 18 active site. 158 166 - T 23-04-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 DC74_RS39470 e78f04cebc5aeea60d4605879cb2c7fe 305 SUPERFAMILY SSF51445 38 278 2.11E-61 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS18825 e008d9243ad94a19d5f413ba3121e131 342 SUPERFAMILY SSF51556 7 337 6.81E-70 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS18825 e008d9243ad94a19d5f413ba3121e131 342 PANTHER PTHR11409 7 336 7.2E-149 T 23-04-2016 DC74_RS18825 e008d9243ad94a19d5f413ba3121e131 342 Gene3D G3DSA:3.20.20.140 7 336 4.8E-83 T 23-04-2016 DC74_RS18825 e008d9243ad94a19d5f413ba3121e131 342 PANTHER PTHR11409:SF36 7 336 7.2E-149 T 23-04-2016 DC74_RS18825 e008d9243ad94a19d5f413ba3121e131 342 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 10 332 2.4E-111 T 23-04-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 DC74_RS18825 e008d9243ad94a19d5f413ba3121e131 342 Pfam PF00962 Adenosine/AMP deaminase 10 330 2.3E-91 T 23-04-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 DC74_RS18825 e008d9243ad94a19d5f413ba3121e131 342 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 277 283 - T 23-04-2016 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: REACT_1698 DC74_RS18435 8ea44af0df71eded1f5b738926b1a567 371 Gene3D G3DSA:3.20.20.70 13 365 3.0E-75 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS18435 8ea44af0df71eded1f5b738926b1a567 371 SUPERFAMILY SSF51412 12 77 2.9E-69 T 23-04-2016 DC74_RS18435 8ea44af0df71eded1f5b738926b1a567 371 SUPERFAMILY SSF51412 113 367 2.9E-69 T 23-04-2016 DC74_RS18435 8ea44af0df71eded1f5b738926b1a567 371 SMART SM01240 14 370 5.8E-28 T 23-04-2016 DC74_RS18435 8ea44af0df71eded1f5b738926b1a567 371 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 4 367 8.2E-195 T 23-04-2016 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- DC74_RS18435 8ea44af0df71eded1f5b738926b1a567 371 PANTHER PTHR11911 217 297 1.2E-16 T 23-04-2016 DC74_RS18435 8ea44af0df71eded1f5b738926b1a567 371 PANTHER PTHR11911 148 199 1.2E-16 T 23-04-2016 DC74_RS18435 8ea44af0df71eded1f5b738926b1a567 371 PANTHER PTHR11911:SF85 217 297 1.2E-16 T 23-04-2016 DC74_RS18435 8ea44af0df71eded1f5b738926b1a567 371 PANTHER PTHR11911:SF85 148 199 1.2E-16 T 23-04-2016 DC74_RS18435 8ea44af0df71eded1f5b738926b1a567 371 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 15 297 1.3E-44 T 23-04-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 DC74_RS32550 d9446b21284b019ba1badf4ca607d889 149 Gene3D G3DSA:3.40.33.10 21 140 1.6E-15 T 23-04-2016 IPR014044 CAP domain DC74_RS32550 d9446b21284b019ba1badf4ca607d889 149 Pfam PF00188 Cysteine-rich secretory protein family 31 145 7.0E-23 T 23-04-2016 IPR014044 CAP domain DC74_RS32550 d9446b21284b019ba1badf4ca607d889 149 PANTHER PTHR31157 24 147 2.1E-44 T 23-04-2016 DC74_RS32550 d9446b21284b019ba1badf4ca607d889 149 SUPERFAMILY SSF55797 23 145 4.71E-26 T 23-04-2016 IPR014044 CAP domain DC74_RS01185 088cadebc334acb8ca1f274b9776b4e3 218 PRINTS PR01438 Universal stress protein signature 2 20 1.7E-12 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS01185 088cadebc334acb8ca1f274b9776b4e3 218 PRINTS PR01438 Universal stress protein signature 96 108 1.7E-12 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS01185 088cadebc334acb8ca1f274b9776b4e3 218 PRINTS PR01438 Universal stress protein signature 114 136 1.7E-12 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS01185 088cadebc334acb8ca1f274b9776b4e3 218 Pfam PF00582 Universal stress protein family 4 136 3.5E-21 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS01185 088cadebc334acb8ca1f274b9776b4e3 218 PANTHER PTHR31964 4 154 1.5E-22 T 23-04-2016 DC74_RS01185 088cadebc334acb8ca1f274b9776b4e3 218 PANTHER PTHR31964:SF42 4 154 1.5E-22 T 23-04-2016 DC74_RS01185 088cadebc334acb8ca1f274b9776b4e3 218 SUPERFAMILY SSF52402 4 139 4.69E-25 T 23-04-2016 DC74_RS01185 088cadebc334acb8ca1f274b9776b4e3 218 Gene3D G3DSA:3.40.50.620 2 139 9.6E-28 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS18355 70b50a6628bbf3f8aee0877765a2ca18 204 PANTHER PTHR30466 10 201 2.0E-36 T 23-04-2016 DC74_RS18355 70b50a6628bbf3f8aee0877765a2ca18 204 Gene3D G3DSA:2.30.110.10 43 200 2.3E-55 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS18355 70b50a6628bbf3f8aee0877765a2ca18 204 SMART SM00903 54 201 3.2E-58 T 23-04-2016 IPR002563 Flavin reductase like domain GO:0010181 DC74_RS18355 70b50a6628bbf3f8aee0877765a2ca18 204 Pfam PF01613 Flavin reductase like domain 55 200 1.3E-35 T 23-04-2016 IPR002563 Flavin reductase like domain GO:0010181 DC74_RS18355 70b50a6628bbf3f8aee0877765a2ca18 204 SUPERFAMILY SSF50475 45 201 1.47E-47 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS10210 6c7a87c54e6ed7075215cc7cce7ea90f 389 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS10210 6c7a87c54e6ed7075215cc7cce7ea90f 389 PANTHER PTHR24220 5 15 9.4E-161 T 23-04-2016 DC74_RS10210 6c7a87c54e6ed7075215cc7cce7ea90f 389 PANTHER PTHR24220:SF374 5 15 9.4E-161 T 23-04-2016 DC74_RS10210 6c7a87c54e6ed7075215cc7cce7ea90f 389 Gene3D G3DSA:3.10.580.10 276 351 2.0E-5 T 23-04-2016 DC74_RS10210 6c7a87c54e6ed7075215cc7cce7ea90f 389 SUPERFAMILY SSF52540 41 268 1.98E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10210 6c7a87c54e6ed7075215cc7cce7ea90f 389 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 283 3.5E-109 T 23-04-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 DC74_RS10210 6c7a87c54e6ed7075215cc7cce7ea90f 389 SMART SM00382 51 240 2.0E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS10210 6c7a87c54e6ed7075215cc7cce7ea90f 389 PANTHER PTHR24220:SF374 39 272 9.4E-161 T 23-04-2016 DC74_RS10210 6c7a87c54e6ed7075215cc7cce7ea90f 389 Pfam PF00005 ABC transporter 45 190 6.4E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS10210 6c7a87c54e6ed7075215cc7cce7ea90f 389 Gene3D G3DSA:3.40.50.300 36 264 3.9E-77 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10210 6c7a87c54e6ed7075215cc7cce7ea90f 389 PANTHER PTHR24220 39 272 9.4E-161 T 23-04-2016 DC74_RS03055 4bce1f31ff005af71cf1891fed2f7e3a 165 Pfam PF01047 MarR family 41 98 6.8E-13 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS03055 4bce1f31ff005af71cf1891fed2f7e3a 165 PANTHER PTHR33164 21 158 1.0E-27 T 23-04-2016 DC74_RS03055 4bce1f31ff005af71cf1891fed2f7e3a 165 PANTHER PTHR33164:SF16 21 158 1.0E-27 T 23-04-2016 DC74_RS03055 4bce1f31ff005af71cf1891fed2f7e3a 165 Gene3D G3DSA:1.10.10.10 21 146 5.6E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03055 4bce1f31ff005af71cf1891fed2f7e3a 165 SMART SM00347 34 134 6.2E-24 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS03055 4bce1f31ff005af71cf1891fed2f7e3a 165 SUPERFAMILY SSF46785 21 147 6.5E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03055 4bce1f31ff005af71cf1891fed2f7e3a 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 1.0E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS03055 4bce1f31ff005af71cf1891fed2f7e3a 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 1.0E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS03055 4bce1f31ff005af71cf1891fed2f7e3a 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 1.0E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS06605 74b690453799d72190ec84026bb17005 217 Gene3D G3DSA:3.40.190.10 50 93 1.2E-4 T 23-04-2016 DC74_RS06605 74b690453799d72190ec84026bb17005 217 PANTHER PTHR30346:SF14 45 205 8.7E-12 T 23-04-2016 DC74_RS06605 74b690453799d72190ec84026bb17005 217 Gene3D G3DSA:3.40.190.10 94 180 1.7E-7 T 23-04-2016 DC74_RS06605 74b690453799d72190ec84026bb17005 217 Pfam PF03466 LysR substrate binding domain 47 205 1.5E-15 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS06605 74b690453799d72190ec84026bb17005 217 PANTHER PTHR30346 45 205 8.7E-12 T 23-04-2016 DC74_RS06605 74b690453799d72190ec84026bb17005 217 SUPERFAMILY SSF53850 45 208 5.61E-15 T 23-04-2016 DC74_RS25310 874c442e6afb1e7297a1ea97354a6bb6 334 SMART SM00829 20 332 8.0E-7 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS25310 874c442e6afb1e7297a1ea97354a6bb6 334 Pfam PF16884 N-terminal domain of oxidoreductase 7 114 3.3E-25 T 23-04-2016 DC74_RS25310 874c442e6afb1e7297a1ea97354a6bb6 334 Gene3D G3DSA:3.40.50.720 141 302 2.7E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS25310 874c442e6afb1e7297a1ea97354a6bb6 334 SUPERFAMILY SSF51735 124 299 5.17E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS25310 874c442e6afb1e7297a1ea97354a6bb6 334 PANTHER PTHR11695 24 334 1.4E-63 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS25310 874c442e6afb1e7297a1ea97354a6bb6 334 PANTHER PTHR11695:SF595 24 334 1.4E-63 T 23-04-2016 DC74_RS25310 874c442e6afb1e7297a1ea97354a6bb6 334 Pfam PF00107 Zinc-binding dehydrogenase 157 283 5.3E-22 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS25310 874c442e6afb1e7297a1ea97354a6bb6 334 SUPERFAMILY SSF50129 5 124 9.43E-27 T 23-04-2016 IPR011032 GroES-like DC74_RS25310 874c442e6afb1e7297a1ea97354a6bb6 334 Gene3D G3DSA:3.90.180.10 3 140 5.3E-32 T 23-04-2016 IPR011032 GroES-like DC74_RS37035 43f664f12b013f1e479138d176066874 431 Gene3D G3DSA:3.30.1490.20 170 241 5.2E-6 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS37035 43f664f12b013f1e479138d176066874 431 SUPERFAMILY SSF56059 147 354 1.39E-10 T 23-04-2016 DC74_RS05745 38e45a15503ab29085e8d7cc43993cd1 425 SUPERFAMILY SSF52777 177 411 4.89E-34 T 23-04-2016 DC74_RS05745 38e45a15503ab29085e8d7cc43993cd1 425 SUPERFAMILY SSF52777 3 169 8.45E-35 T 23-04-2016 DC74_RS05745 38e45a15503ab29085e8d7cc43993cd1 425 PANTHER PTHR24095 2 410 5.2E-54 T 23-04-2016 DC74_RS05745 38e45a15503ab29085e8d7cc43993cd1 425 PANTHER PTHR24095:SF137 2 410 5.2E-54 T 23-04-2016 DC74_RS05745 38e45a15503ab29085e8d7cc43993cd1 425 Pfam PF00668 Condensation domain 3 285 6.9E-38 T 23-04-2016 IPR001242 Condensation domain DC74_RS16800 5abf9c227a9e79d03addf7330a19ae52 213 SUPERFAMILY SSF46689 31 87 4.39E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS16800 5abf9c227a9e79d03addf7330a19ae52 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 49 80 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS16800 5abf9c227a9e79d03addf7330a19ae52 213 Pfam PF16859 Bacterial transcriptional repressor C-terminal 95 203 6.5E-33 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS16800 5abf9c227a9e79d03addf7330a19ae52 213 Gene3D G3DSA:1.10.357.10 76 212 2.0E-40 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS16800 5abf9c227a9e79d03addf7330a19ae52 213 PANTHER PTHR30328 12 195 3.9E-69 T 23-04-2016 DC74_RS16800 5abf9c227a9e79d03addf7330a19ae52 213 Gene3D G3DSA:1.10.10.60 31 75 2.1E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS16800 5abf9c227a9e79d03addf7330a19ae52 213 PANTHER PTHR30328:SF21 12 195 3.9E-69 T 23-04-2016 DC74_RS16800 5abf9c227a9e79d03addf7330a19ae52 213 SUPERFAMILY SSF48498 95 210 2.14E-27 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS16800 5abf9c227a9e79d03addf7330a19ae52 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 82 4.4E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS14835 dc51839ffaf09e3db17b8ea1912850fd 193 PANTHER PTHR30055:SF60 2 193 9.1E-55 T 23-04-2016 DC74_RS14835 dc51839ffaf09e3db17b8ea1912850fd 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.5E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS14835 dc51839ffaf09e3db17b8ea1912850fd 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.5E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS14835 dc51839ffaf09e3db17b8ea1912850fd 193 SUPERFAMILY SSF46689 5 83 5.49E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS14835 dc51839ffaf09e3db17b8ea1912850fd 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 2.4E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS14835 dc51839ffaf09e3db17b8ea1912850fd 193 PANTHER PTHR30055 2 193 9.1E-55 T 23-04-2016 DC74_RS14835 dc51839ffaf09e3db17b8ea1912850fd 193 SUPERFAMILY SSF48498 119 192 1.47E-5 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS14835 dc51839ffaf09e3db17b8ea1912850fd 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 53 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS14835 dc51839ffaf09e3db17b8ea1912850fd 193 Gene3D G3DSA:1.10.357.10 7 192 9.1E-33 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS02185 00cea3d5197455ed0aea209d939c6914 141 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 86 7.1E-9 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS02185 00cea3d5197455ed0aea209d939c6914 141 Gene3D G3DSA:2.30.110.10 3 137 6.9E-21 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS02185 00cea3d5197455ed0aea209d939c6914 141 SUPERFAMILY SSF50475 2 140 2.24E-21 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS18830 cdfb50456c2cb79886d85318018ce2d3 354 Pfam PF01565 FAD binding domain 26 154 1.6E-20 T 23-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DC74_RS18830 cdfb50456c2cb79886d85318018ce2d3 354 PANTHER PTHR21071:SF6 6 354 2.4E-143 T 23-04-2016 DC74_RS18830 cdfb50456c2cb79886d85318018ce2d3 354 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 216 350 4.1E-39 T 23-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS18830 cdfb50456c2cb79886d85318018ce2d3 354 Gene3D G3DSA:3.30.43.10 11 75 5.6E-23 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS18830 cdfb50456c2cb79886d85318018ce2d3 354 SUPERFAMILY SSF56176 11 189 1.68E-36 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS18830 cdfb50456c2cb79886d85318018ce2d3 354 SUPERFAMILY SSF56194 216 352 7.59E-35 T 23-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS18830 cdfb50456c2cb79886d85318018ce2d3 354 Gene3D G3DSA:3.90.78.10 243 353 2.7E-45 T 23-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS18830 cdfb50456c2cb79886d85318018ce2d3 354 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 12 346 1.0E-49 T 23-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS18830 cdfb50456c2cb79886d85318018ce2d3 354 PANTHER PTHR21071 6 354 2.4E-143 T 23-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS18830 cdfb50456c2cb79886d85318018ce2d3 354 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 354 77.884 T 23-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS18830 cdfb50456c2cb79886d85318018ce2d3 354 Gene3D G3DSA:3.30.465.10 226 242 6.8E-48 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS18830 cdfb50456c2cb79886d85318018ce2d3 354 Gene3D G3DSA:3.30.465.10 80 191 6.8E-48 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS35165 2d6bfeac1ae02e04b288d3b3ea4cf257 135 SMART SM00881 12 105 2.2E-17 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS35165 2d6bfeac1ae02e04b288d3b3ea4cf257 135 PANTHER PTHR33303 3 134 6.7E-43 T 23-04-2016 DC74_RS35165 2d6bfeac1ae02e04b288d3b3ea4cf257 135 Gene3D G3DSA:3.40.50.720 6 134 1.2E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS35165 2d6bfeac1ae02e04b288d3b3ea4cf257 135 SUPERFAMILY SSF51735 17 135 7.09E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS35165 2d6bfeac1ae02e04b288d3b3ea4cf257 135 Pfam PF13380 CoA binding domain 18 131 1.1E-35 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS07530 995a5ed220c671a0cddc2ed90321548a 525 PANTHER PTHR38686 7 505 8.0E-92 T 23-04-2016 DC74_RS07530 995a5ed220c671a0cddc2ed90321548a 525 SUPERFAMILY SSF56317 219 481 6.67E-42 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS07530 995a5ed220c671a0cddc2ed90321548a 525 Gene3D G3DSA:3.60.110.10 219 480 5.3E-37 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS07530 995a5ed220c671a0cddc2ed90321548a 525 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 15 486 16.175 T 23-04-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 DC74_RS07530 995a5ed220c671a0cddc2ed90321548a 525 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 70 447 2.9E-83 T 23-04-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 DC74_RS07530 995a5ed220c671a0cddc2ed90321548a 525 Pfam PF00795 Carbon-nitrogen hydrolase 224 457 3.0E-24 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 Gene3D G3DSA:3.40.50.300 645 808 3.2E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 PANTHER PTHR11070:SF25 495 688 6.2E-157 T 23-04-2016 DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 Pfam PF00580 UvrD/REP helicase N-terminal domain 568 619 3.3E-6 T 23-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 Pfam PF13245 Part of AAA domain 233 289 5.1E-13 T 23-04-2016 DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 Pfam PF13538 UvrD-like helicase C-terminal domain 762 803 3.6E-7 T 23-04-2016 IPR027785 UvrD-like helicase C-terminal domain DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 PANTHER PTHR11070 709 809 6.2E-157 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 PANTHER PTHR11070 495 688 6.2E-157 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 PANTHER PTHR11070 122 389 6.2E-157 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 Gene3D G3DSA:3.40.50.300 456 621 3.9E-31 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 Gene3D G3DSA:3.40.50.300 226 293 3.9E-31 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 PANTHER PTHR11070:SF25 709 809 6.2E-157 T 23-04-2016 DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 PANTHER PTHR11070:SF25 122 389 6.2E-157 T 23-04-2016 DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 SUPERFAMILY SSF52540 407 464 2.1E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 SUPERFAMILY SSF52540 219 297 2.1E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16625 c25097f93a4591370aa5a05370af13e6 822 SUPERFAMILY SSF52540 571 809 2.1E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10825 040d5c828495814b30da08ba89125dba 342 SUPERFAMILY SSF56672 20 179 6.0E-30 T 23-04-2016 DC74_RS10825 040d5c828495814b30da08ba89125dba 342 PANTHER PTHR11076 25 295 1.3E-52 T 23-04-2016 DC74_RS10825 040d5c828495814b30da08ba89125dba 342 Gene3D G3DSA:3.30.1490.100 187 291 2.5E-15 T 23-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS10825 040d5c828495814b30da08ba89125dba 342 Gene3D G3DSA:3.30.70.270 25 102 1.4E-6 T 23-04-2016 DC74_RS10825 040d5c828495814b30da08ba89125dba 342 Pfam PF00817 impB/mucB/samB family 25 95 3.4E-6 T 23-04-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS10825 040d5c828495814b30da08ba89125dba 342 Pfam PF11799 impB/mucB/samB family C-terminal domain 181 294 1.1E-13 T 23-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS10825 040d5c828495814b30da08ba89125dba 342 SUPERFAMILY SSF100879 185 281 1.73E-15 T 23-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS10825 040d5c828495814b30da08ba89125dba 342 Gene3D G3DSA:1.10.150.20 109 182 7.4E-17 T 23-04-2016 DC74_RS24045 864ddc613c4f005b9d0dda48a232a9a2 106 SMART SM00830 35 103 0.0015 T 23-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS24045 864ddc613c4f005b9d0dda48a232a9a2 106 SUPERFAMILY SSF48600 30 88 1.83E-9 T 23-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS24045 864ddc613c4f005b9d0dda48a232a9a2 106 Gene3D G3DSA:1.20.59.10 23 89 5.0E-9 T 23-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS24045 864ddc613c4f005b9d0dda48a232a9a2 106 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 30 104 4.4E-16 T 23-04-2016 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal DC74_RS24045 864ddc613c4f005b9d0dda48a232a9a2 106 Pfam PF01817 Chorismate mutase type II 35 85 5.1E-6 T 23-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS09990 f76bf6c8787e06d59155eed8167f6b2a 271 Gene3D G3DSA:1.10.1040.10 177 271 5.8E-33 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS09990 f76bf6c8787e06d59155eed8167f6b2a 271 PANTHER PTHR23309 1 271 8.5E-156 T 23-04-2016 DC74_RS09990 f76bf6c8787e06d59155eed8167f6b2a 271 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 175 271 1.7E-32 T 23-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS09990 f76bf6c8787e06d59155eed8167f6b2a 271 Gene3D G3DSA:3.40.50.720 1 176 2.2E-50 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09990 f76bf6c8787e06d59155eed8167f6b2a 271 PIRSF PIRSF000105 1 271 5.4E-71 T 23-04-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 DC74_RS09990 f76bf6c8787e06d59155eed8167f6b2a 271 SUPERFAMILY SSF51735 1 172 2.11E-42 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09990 f76bf6c8787e06d59155eed8167f6b2a 271 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1 172 2.8E-54 T 23-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS09990 f76bf6c8787e06d59155eed8167f6b2a 271 PANTHER PTHR23309:SF24 1 271 8.5E-156 T 23-04-2016 DC74_RS09990 f76bf6c8787e06d59155eed8167f6b2a 271 SUPERFAMILY SSF48179 175 271 2.81E-29 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS16225 fe9b542c472351982cca79ca9ac68cb0 306 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 28 232 2.6E-33 T 23-04-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal DC74_RS16225 fe9b542c472351982cca79ca9ac68cb0 306 Pfam PF02096 60Kd inner membrane protein 29 231 3.1E-29 T 23-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 DC74_RS16225 fe9b542c472351982cca79ca9ac68cb0 306 PANTHER PTHR12428 151 281 9.9E-22 T 23-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 DC74_RS16225 fe9b542c472351982cca79ca9ac68cb0 306 PANTHER PTHR12428 28 129 9.9E-22 T 23-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 DC74_RS22815 32c4212e4d6e83397351aa4f60bb8ec0 63 Gene3D G3DSA:3.30.70.20 1 61 7.2E-16 T 23-04-2016 DC74_RS22815 32c4212e4d6e83397351aa4f60bb8ec0 63 PANTHER PTHR36923 1 61 1.9E-13 T 23-04-2016 DC74_RS22815 32c4212e4d6e83397351aa4f60bb8ec0 63 SUPERFAMILY SSF54862 3 60 1.61E-12 T 23-04-2016 DC74_RS22815 32c4212e4d6e83397351aa4f60bb8ec0 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 2.5E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS22815 32c4212e4d6e83397351aa4f60bb8ec0 63 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 2.5E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS22815 32c4212e4d6e83397351aa4f60bb8ec0 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 2.5E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS22815 32c4212e4d6e83397351aa4f60bb8ec0 63 Pfam PF13459 4Fe-4S single cluster domain 3 60 1.2E-11 T 23-04-2016 DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 Gene3D G3DSA:3.30.70.920 56 135 8.9E-20 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 23-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 9.0E-11 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 9.0E-11 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 9.0E-11 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 PANTHER PTHR30154:SF26 2 145 1.0E-88 T 23-04-2016 DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 SUPERFAMILY SSF54909 65 144 1.1E-13 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 PANTHER PTHR30154 2 145 1.0E-88 T 23-04-2016 DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 SUPERFAMILY SSF46785 2 63 1.11E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 Gene3D G3DSA:1.10.10.10 5 55 2.8E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 Pfam PF01037 Lrp/AsnC ligand binding domain 70 139 2.1E-14 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 2.0E-16 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS09315 359a76b1e9e120aa2c82ac9aeb19a040 151 SMART SM00344 3 110 4.5E-30 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS26855 81b3dbc5cdcaf24e597b37687bd1850f 361 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 62 75 - T 23-04-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 DC74_RS26855 81b3dbc5cdcaf24e597b37687bd1850f 361 TIGRFAM TIGR00260 thrC: threonine synthase 18 335 2.4E-97 T 23-04-2016 IPR004450 Threonine synthase-like DC74_RS26855 81b3dbc5cdcaf24e597b37687bd1850f 361 PIRSF PIRSF038945 2 360 1.2E-167 T 23-04-2016 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1|UniPathway: UPA00050 DC74_RS26855 81b3dbc5cdcaf24e597b37687bd1850f 361 PANTHER PTHR10314 15 338 6.0E-139 T 23-04-2016 DC74_RS26855 81b3dbc5cdcaf24e597b37687bd1850f 361 Gene3D G3DSA:3.40.50.1100 155 336 3.4E-47 T 23-04-2016 DC74_RS26855 81b3dbc5cdcaf24e597b37687bd1850f 361 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 35 328 8.6E-73 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS26855 81b3dbc5cdcaf24e597b37687bd1850f 361 Gene3D G3DSA:3.40.50.1100 70 154 1.8E-42 T 23-04-2016 DC74_RS26855 81b3dbc5cdcaf24e597b37687bd1850f 361 SUPERFAMILY SSF53686 13 342 6.16E-102 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS26855 81b3dbc5cdcaf24e597b37687bd1850f 361 PANTHER PTHR10314:SF5 15 338 6.0E-139 T 23-04-2016 DC74_RS36420 c28c45e3f3ce5f95e86963a6f9ae7f49 248 SUPERFAMILY SSF55781 69 246 1.91E-44 T 23-04-2016 IPR029016 GAF domain-like DC74_RS36420 c28c45e3f3ce5f95e86963a6f9ae7f49 248 PANTHER PTHR30136:SF7 16 235 1.6E-54 T 23-04-2016 DC74_RS36420 c28c45e3f3ce5f95e86963a6f9ae7f49 248 SMART SM00346 13 101 6.7E-20 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS36420 c28c45e3f3ce5f95e86963a6f9ae7f49 248 SUPERFAMILY SSF46785 15 82 4.69E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36420 c28c45e3f3ce5f95e86963a6f9ae7f49 248 Pfam PF09339 IclR helix-turn-helix domain 16 66 1.4E-14 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS36420 c28c45e3f3ce5f95e86963a6f9ae7f49 248 Gene3D G3DSA:3.30.450.40 81 246 1.8E-49 T 23-04-2016 IPR029016 GAF domain-like DC74_RS36420 c28c45e3f3ce5f95e86963a6f9ae7f49 248 Pfam PF01614 Bacterial transcriptional regulator 129 246 7.1E-30 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS36420 c28c45e3f3ce5f95e86963a6f9ae7f49 248 Gene3D G3DSA:1.10.10.10 14 79 9.1E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36420 c28c45e3f3ce5f95e86963a6f9ae7f49 248 PANTHER PTHR30136 16 235 1.6E-54 T 23-04-2016 DC74_RS20405 5a93174e975ff77504dd072e732136fc 523 Pfam PF00994 Probable molybdopterin binding domain 280 414 1.0E-23 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS20405 5a93174e975ff77504dd072e732136fc 523 Gene3D G3DSA:2.40.340.10 428 493 2.2E-5 T 23-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS20405 5a93174e975ff77504dd072e732136fc 523 Pfam PF03454 MoeA C-terminal region (domain IV) 426 494 1.8E-9 T 23-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS20405 5a93174e975ff77504dd072e732136fc 523 Gene3D G3DSA:3.90.105.10 232 261 2.1E-15 T 23-04-2016 DC74_RS20405 5a93174e975ff77504dd072e732136fc 523 SMART SM00852 279 415 5.7E-27 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS20405 5a93174e975ff77504dd072e732136fc 523 SUPERFAMILY SSF53218 276 417 1.26E-28 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS20405 5a93174e975ff77504dd072e732136fc 523 PANTHER PTHR10192 88 511 2.7E-84 T 23-04-2016 DC74_RS20405 5a93174e975ff77504dd072e732136fc 523 Gene3D G3DSA:2.170.190.11 138 231 3.6E-16 T 23-04-2016 DC74_RS20405 5a93174e975ff77504dd072e732136fc 523 Pfam PF03453 MoeA N-terminal region (domain I and II) 102 266 8.9E-28 T 23-04-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS20405 5a93174e975ff77504dd072e732136fc 523 SUPERFAMILY SSF63882 95 275 2.88E-34 T 23-04-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS20405 5a93174e975ff77504dd072e732136fc 523 Gene3D G3DSA:3.40.980.10 262 427 2.3E-43 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS20405 5a93174e975ff77504dd072e732136fc 523 SUPERFAMILY SSF63867 425 496 1.07E-5 T 23-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS24825 84055cbd267049a716dea81a1b381112 526 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 5 522 1.2E-227 T 23-04-2016 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 DC74_RS24825 84055cbd267049a716dea81a1b381112 526 SUPERFAMILY SSF51703 2 520 3.4E-204 T 23-04-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 DC74_RS24825 84055cbd267049a716dea81a1b381112 526 Gene3D G3DSA:3.20.20.240 5 520 1.0E-222 T 23-04-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 DC74_RS24825 84055cbd267049a716dea81a1b381112 526 Pfam PF01642 Methylmalonyl-CoA mutase 6 518 3.9E-218 T 23-04-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 DC74_RS24825 84055cbd267049a716dea81a1b381112 526 PANTHER PTHR23408:SF7 4 526 2.9E-279 T 23-04-2016 DC74_RS24825 84055cbd267049a716dea81a1b381112 526 PANTHER PTHR23408 4 526 2.9E-279 T 23-04-2016 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PRINTS PR00385 P450 superfamily signature 277 288 1.5E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PRINTS PR00385 P450 superfamily signature 353 364 1.5E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PRINTS PR00385 P450 superfamily signature 242 259 1.5E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PRINTS PR00385 P450 superfamily signature 344 353 1.5E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 Pfam PF00067 Cytochrome P450 273 373 1.7E-17 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 Pfam PF00067 Cytochrome P450 187 261 4.4E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PANTHER PTHR11712 11 404 1.5E-82 T 23-04-2016 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 SUPERFAMILY SSF48264 21 404 4.45E-90 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 Gene3D G3DSA:1.10.630.10 13 404 2.2E-117 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PRINTS PR00359 B-class P450 signature 344 353 1.7E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PRINTS PR00359 B-class P450 signature 277 288 1.7E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PRINTS PR00359 B-class P450 signature 140 156 1.7E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PRINTS PR00359 B-class P450 signature 295 322 1.7E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PRINTS PR00359 B-class P450 signature 157 172 1.7E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PRINTS PR00359 B-class P450 signature 323 338 1.7E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PRINTS PR00359 B-class P450 signature 195 217 1.7E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02285 0167a2bbd63cb70e2350fa1998311931 404 PRINTS PR00359 B-class P450 signature 353 364 1.7E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS22340 74d3d4f31c9eed697d2d0cacb09c6044 121 Gene3D G3DSA:1.10.10.10 5 107 7.6E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22340 74d3d4f31c9eed697d2d0cacb09c6044 121 Pfam PF12840 Helix-turn-helix domain 8 68 4.9E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22340 74d3d4f31c9eed697d2d0cacb09c6044 121 PANTHER PTHR33154 4 100 6.9E-20 T 23-04-2016 DC74_RS22340 74d3d4f31c9eed697d2d0cacb09c6044 121 SMART SM00418 9 91 1.1E-23 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS22340 74d3d4f31c9eed697d2d0cacb09c6044 121 PANTHER PTHR33154:SF6 4 100 6.9E-20 T 23-04-2016 DC74_RS22340 74d3d4f31c9eed697d2d0cacb09c6044 121 SUPERFAMILY SSF46785 6 101 3.7E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22340 74d3d4f31c9eed697d2d0cacb09c6044 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 4.0E-13 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS22340 74d3d4f31c9eed697d2d0cacb09c6044 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 4.0E-13 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS22340 74d3d4f31c9eed697d2d0cacb09c6044 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 4.0E-13 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS26940 869973330794804e11c605bb640f5b0e 305 Pfam PF00231 ATP synthase 5 297 7.8E-83 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26940 869973330794804e11c605bb640f5b0e 305 Gene3D G3DSA:1.10.287.80 212 245 2.9E-27 T 23-04-2016 DC74_RS26940 869973330794804e11c605bb640f5b0e 305 Gene3D G3DSA:1.10.287.80 20 61 2.9E-27 T 23-04-2016 DC74_RS26940 869973330794804e11c605bb640f5b0e 305 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 297 1.9E-90 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26940 869973330794804e11c605bb640f5b0e 305 PRINTS PR00126 ATP synthase gamma subunit signature 244 263 2.7E-29 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26940 869973330794804e11c605bb640f5b0e 305 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 2.7E-29 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26940 869973330794804e11c605bb640f5b0e 305 PRINTS PR00126 ATP synthase gamma subunit signature 275 296 2.7E-29 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26940 869973330794804e11c605bb640f5b0e 305 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 2.7E-29 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26940 869973330794804e11c605bb640f5b0e 305 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 297 33.139 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS26940 869973330794804e11c605bb640f5b0e 305 Gene3D G3DSA:3.40.1380.10 64 197 3.4E-39 T 23-04-2016 DC74_RS26940 869973330794804e11c605bb640f5b0e 305 SUPERFAMILY SSF52943 3 297 6.02E-79 T 23-04-2016 IPR023633 ATPase, F1 complex, gamma subunit domain DC74_RS26940 869973330794804e11c605bb640f5b0e 305 Gene3D G3DSA:1.10.287.80 246 292 1.2E-23 T 23-04-2016 DC74_RS26940 869973330794804e11c605bb640f5b0e 305 PANTHER PTHR11693 3 299 1.2E-100 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 DC74_RS20735 a9785171f5fe3becf4cc44bb50880c20 205 SUPERFAMILY SSF55729 5 140 1.92E-12 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS20735 a9785171f5fe3becf4cc44bb50880c20 205 Gene3D G3DSA:3.40.630.30 7 136 3.3E-11 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS20735 a9785171f5fe3becf4cc44bb50880c20 205 Pfam PF00583 Acetyltransferase (GNAT) family 65 138 3.2E-8 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS17720 03cf4febeb37febd7230f49e1111d970 286 SMART SM00422 36 104 3.4E-13 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17720 03cf4febeb37febd7230f49e1111d970 286 PANTHER PTHR30204 28 114 2.6E-38 T 23-04-2016 DC74_RS17720 03cf4febeb37febd7230f49e1111d970 286 Pfam PF13411 MerR HTH family regulatory protein 36 102 3.8E-18 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17720 03cf4febeb37febd7230f49e1111d970 286 Gene3D G3DSA:1.10.1660.10 37 108 2.2E-18 T 23-04-2016 DC74_RS17720 03cf4febeb37febd7230f49e1111d970 286 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 48 5.6E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17720 03cf4febeb37febd7230f49e1111d970 286 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 48 61 5.6E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17720 03cf4febeb37febd7230f49e1111d970 286 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 71 91 5.6E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17720 03cf4febeb37febd7230f49e1111d970 286 SUPERFAMILY SSF46955 36 106 2.01E-16 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS17720 03cf4febeb37febd7230f49e1111d970 286 PANTHER PTHR30204:SF13 28 114 2.6E-38 T 23-04-2016 DC74_RS13425 bc47cbae2b143551b7259403b679c7ea 199 SUPERFAMILY SSF48498 80 198 6.23E-24 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS13425 bc47cbae2b143551b7259403b679c7ea 199 Gene3D G3DSA:1.10.10.60 11 58 7.3E-24 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS13425 bc47cbae2b143551b7259403b679c7ea 199 Gene3D G3DSA:1.10.357.10 59 198 1.5E-41 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS13425 bc47cbae2b143551b7259403b679c7ea 199 SUPERFAMILY SSF46689 11 75 7.48E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS13425 bc47cbae2b143551b7259403b679c7ea 199 Pfam PF16859 Bacterial transcriptional repressor C-terminal 79 191 6.3E-26 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS13425 bc47cbae2b143551b7259403b679c7ea 199 PANTHER PTHR30055 3 198 2.3E-46 T 23-04-2016 DC74_RS13425 bc47cbae2b143551b7259403b679c7ea 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 6.9E-14 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13425 bc47cbae2b143551b7259403b679c7ea 199 PANTHER PTHR30055:SF66 3 198 2.3E-46 T 23-04-2016 DC74_RS13425 bc47cbae2b143551b7259403b679c7ea 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.6E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13425 bc47cbae2b143551b7259403b679c7ea 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.6E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13535 064cca9fd36a3c8227360cca9cc31e54 265 PANTHER PTHR30283 2 264 7.0E-65 T 23-04-2016 DC74_RS13535 064cca9fd36a3c8227360cca9cc31e54 265 PANTHER PTHR30283:SF3 2 264 7.0E-65 T 23-04-2016 DC74_RS13535 064cca9fd36a3c8227360cca9cc31e54 265 Pfam PF03883 Protein of unknown function (DUF328) 2 247 3.1E-38 T 23-04-2016 IPR005583 Peroxide stress protein YaaA DC74_RS36980 e9e7616fb06e434485164d7826dc166a 164 PANTHER PTHR36440:SF1 18 164 1.5E-34 T 23-04-2016 DC74_RS36980 e9e7616fb06e434485164d7826dc166a 164 PANTHER PTHR36440 18 164 1.5E-34 T 23-04-2016 DC74_RS36980 e9e7616fb06e434485164d7826dc166a 164 SUPERFAMILY SSF51182 15 158 3.89E-31 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS36980 e9e7616fb06e434485164d7826dc166a 164 Gene3D G3DSA:2.60.120.10 22 145 3.1E-37 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS36980 e9e7616fb06e434485164d7826dc166a 164 Pfam PF07883 Cupin domain 53 120 3.9E-21 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 PANTHER PTHR13789:SF90 204 483 2.8E-93 T 23-04-2016 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 PANTHER PTHR13789:SF90 28 188 2.8E-93 T 23-04-2016 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 347 363 4.5E-45 T 23-04-2016 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 383 399 4.5E-45 T 23-04-2016 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 332 347 4.5E-45 T 23-04-2016 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 54 76 4.5E-45 T 23-04-2016 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 365 383 4.5E-45 T 23-04-2016 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 209 224 4.5E-45 T 23-04-2016 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 SUPERFAMILY SSF51905 328 443 3.16E-62 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 SUPERFAMILY SSF51905 53 230 3.16E-62 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 Pfam PF01494 FAD binding domain 53 397 3.3E-80 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 PANTHER PTHR13789 204 483 2.8E-93 T 23-04-2016 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 PANTHER PTHR13789 28 188 2.8E-93 T 23-04-2016 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 Gene3D G3DSA:3.50.50.60 53 235 1.8E-58 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19355 be1c8f36f7e8f2e33930b639b2ea286b 587 Gene3D G3DSA:3.50.50.60 320 403 1.8E-58 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03915 8a8e3c920166e593b62f94d223047b2e 192 SUPERFAMILY SSF47741 90 179 1.28E-27 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS03915 8a8e3c920166e593b62f94d223047b2e 192 Pfam PF01799 [2Fe-2S] binding domain 79 169 1.1E-28 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS03915 8a8e3c920166e593b62f94d223047b2e 192 SUPERFAMILY SSF54292 9 94 2.88E-27 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS03915 8a8e3c920166e593b62f94d223047b2e 192 Gene3D G3DSA:3.10.20.30 8 80 1.0E-31 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS03915 8a8e3c920166e593b62f94d223047b2e 192 Gene3D G3DSA:1.10.150.120 81 181 7.4E-32 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS03915 8a8e3c920166e593b62f94d223047b2e 192 PANTHER PTHR11908 5 168 1.5E-41 T 23-04-2016 DC74_RS03915 8a8e3c920166e593b62f94d223047b2e 192 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 45 53 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS03915 8a8e3c920166e593b62f94d223047b2e 192 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 62 2.5E-10 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS06080 30e3e372b44edada6150d3ad9636aea0 444 Gene3D G3DSA:2.60.40.1260 5 67 6.2E-7 T 23-04-2016 IPR001322 Lamin Tail Domain DC74_RS06080 30e3e372b44edada6150d3ad9636aea0 444 Pfam PF00932 Lamin Tail Domain 8 102 4.8E-14 T 23-04-2016 IPR001322 Lamin Tail Domain DC74_RS06080 30e3e372b44edada6150d3ad9636aea0 444 SUPERFAMILY SSF74853 4 93 3.53E-12 T 23-04-2016 IPR001322 Lamin Tail Domain DC74_RS06700 727283da35270676f58c65d62465f044 247 PANTHER PTHR30136:SF7 1 246 4.0E-63 T 23-04-2016 DC74_RS06700 727283da35270676f58c65d62465f044 247 SUPERFAMILY SSF46785 1 71 7.92E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06700 727283da35270676f58c65d62465f044 247 Pfam PF01614 Bacterial transcriptional regulator 118 241 1.6E-34 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS06700 727283da35270676f58c65d62465f044 247 PANTHER PTHR30136 1 246 4.0E-63 T 23-04-2016 DC74_RS06700 727283da35270676f58c65d62465f044 247 SUPERFAMILY SSF55781 58 245 2.68E-47 T 23-04-2016 IPR029016 GAF domain-like DC74_RS06700 727283da35270676f58c65d62465f044 247 Gene3D G3DSA:1.10.10.10 1 71 2.6E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06700 727283da35270676f58c65d62465f044 247 Pfam PF09339 IclR helix-turn-helix domain 3 52 1.1E-15 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS06700 727283da35270676f58c65d62465f044 247 SMART SM00346 1 90 3.6E-23 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS06700 727283da35270676f58c65d62465f044 247 Gene3D G3DSA:3.30.450.40 72 246 4.4E-53 T 23-04-2016 IPR029016 GAF domain-like DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 PANTHER PTHR22847 201 248 5.0E-39 T 23-04-2016 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 PANTHER PTHR22847 1 162 5.0E-39 T 23-04-2016 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 PANTHER PTHR22847 409 558 5.0E-39 T 23-04-2016 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SMART SM00320 35 73 3.4E-5 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SMART SM00320 197 236 0.036 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SMART SM00320 479 519 0.0053 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SMART SM00320 399 436 8.5 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SMART SM00320 117 156 1.1E-8 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SMART SM00320 1 32 8.3 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SMART SM00320 76 115 0.0016 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SMART SM00320 522 561 260.0 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SMART SM00320 439 478 2.7 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 Gene3D G3DSA:2.130.10.10 355 557 3.0E-25 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SUPERFAMILY SSF50998 352 558 5.1E-31 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SUPERFAMILY SSF50998 169 315 5.1E-31 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SUPERFAMILY SSF50978 3 168 2.86E-47 T 23-04-2016 IPR017986 WD40-repeat-containing domain GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 SUPERFAMILY SSF50978 201 316 2.86E-47 T 23-04-2016 IPR017986 WD40-repeat-containing domain GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 Pfam PF00400 WD domain, G-beta repeat 119 155 3.6E-5 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 Pfam PF00400 WD domain, G-beta repeat 45 73 0.0013 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 Pfam PF00400 WD domain, G-beta repeat 487 519 9.3E-4 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 Pfam PF00400 WD domain, G-beta repeat 94 115 0.036 T 23-04-2016 IPR001680 WD40 repeat GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 Gene3D G3DSA:2.130.10.10 3 278 1.2E-47 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS39265 398ebeb01a02bfba50873b5e2be1bf12 565 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 223 237 - T 23-04-2016 IPR019775 WD40 repeat, conserved site DC74_RS05400 3b63f07315a86e3d8a6945b6aed61941 292 Pfam PF04199 Putative cyclase 27 227 6.0E-26 T 23-04-2016 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|UniPathway: UPA00333 DC74_RS05400 3b63f07315a86e3d8a6945b6aed61941 292 PANTHER PTHR34861:SF5 134 292 9.7E-21 T 23-04-2016 DC74_RS05400 3b63f07315a86e3d8a6945b6aed61941 292 Gene3D G3DSA:3.50.30.50 24 291 3.1E-51 T 23-04-2016 DC74_RS05400 3b63f07315a86e3d8a6945b6aed61941 292 SUPERFAMILY SSF102198 25 291 3.92E-39 T 23-04-2016 DC74_RS05400 3b63f07315a86e3d8a6945b6aed61941 292 PANTHER PTHR34861 134 292 9.7E-21 T 23-04-2016 DC74_RS08875 e483f8867c12527b3735ce903e9d7933 643 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS08875 e483f8867c12527b3735ce903e9d7933 643 Pfam PF00069 Protein kinase domain 14 281 1.3E-37 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS08875 e483f8867c12527b3735ce903e9d7933 643 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 43 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS08875 e483f8867c12527b3735ce903e9d7933 643 Gene3D G3DSA:3.30.200.20 6 83 4.5E-23 T 23-04-2016 DC74_RS08875 e483f8867c12527b3735ce903e9d7933 643 PANTHER PTHR24362 7 320 2.2E-84 T 23-04-2016 DC74_RS08875 e483f8867c12527b3735ce903e9d7933 643 PANTHER PTHR24362:SF160 7 320 2.2E-84 T 23-04-2016 DC74_RS08875 e483f8867c12527b3735ce903e9d7933 643 SMART SM00220 14 288 9.7E-54 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS08875 e483f8867c12527b3735ce903e9d7933 643 SUPERFAMILY SSF56112 7 309 4.37E-62 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS08875 e483f8867c12527b3735ce903e9d7933 643 Gene3D G3DSA:1.10.510.10 84 283 2.9E-39 T 23-04-2016 DC74_RS02765 f32d455fbf45d0c75d034d4b8fdeb1c9 124 PANTHER PTHR37950 2 114 5.0E-19 T 23-04-2016 DC74_RS02765 f32d455fbf45d0c75d034d4b8fdeb1c9 124 SUPERFAMILY SSF55331 2 116 4.83E-21 T 23-04-2016 IPR014347 Tautomerase/MIF superfamily DC74_RS02765 f32d455fbf45d0c75d034d4b8fdeb1c9 124 PANTHER PTHR37950:SF1 2 114 5.0E-19 T 23-04-2016 DC74_RS02765 f32d455fbf45d0c75d034d4b8fdeb1c9 124 Gene3D G3DSA:3.30.429.10 1 118 1.3E-25 T 23-04-2016 DC74_RS23765 0345143496a476b0c8d61d3950b4af60 93 Pfam PF10745 Protein of unknown function (DUF2530) 20 77 4.3E-5 T 23-04-2016 IPR019681 Protein of unknown function DUF2530 DC74_RS01060 38847f21d0f7b9d1d1fc4a93cc7fb254 160 PANTHER PTHR33164:SF10 17 160 6.7E-28 T 23-04-2016 DC74_RS01060 38847f21d0f7b9d1d1fc4a93cc7fb254 160 SUPERFAMILY SSF46785 18 151 2.45E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01060 38847f21d0f7b9d1d1fc4a93cc7fb254 160 PANTHER PTHR33164 17 160 6.7E-28 T 23-04-2016 DC74_RS01060 38847f21d0f7b9d1d1fc4a93cc7fb254 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 3.1E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS01060 38847f21d0f7b9d1d1fc4a93cc7fb254 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 3.1E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS01060 38847f21d0f7b9d1d1fc4a93cc7fb254 160 Gene3D G3DSA:1.10.10.10 17 151 3.9E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01060 38847f21d0f7b9d1d1fc4a93cc7fb254 160 SMART SM00347 35 135 1.9E-14 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS01060 38847f21d0f7b9d1d1fc4a93cc7fb254 160 Pfam PF01047 MarR family 45 99 1.1E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS00260 edbf77761c359d5502470282fe3a52c5 330 SMART SM00342 239 322 4.5E-21 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS00260 edbf77761c359d5502470282fe3a52c5 330 SUPERFAMILY SSF52317 16 205 5.5E-43 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS00260 edbf77761c359d5502470282fe3a52c5 330 Pfam PF12833 Helix-turn-helix domain 245 323 1.1E-15 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS00260 edbf77761c359d5502470282fe3a52c5 330 SUPERFAMILY SSF46689 223 272 3.05E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00260 edbf77761c359d5502470282fe3a52c5 330 PANTHER PTHR11019:SF68 10 330 4.5E-121 T 23-04-2016 DC74_RS00260 edbf77761c359d5502470282fe3a52c5 330 Pfam PF01965 DJ-1/PfpI family 74 184 4.1E-13 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS00260 edbf77761c359d5502470282fe3a52c5 330 Gene3D G3DSA:3.40.50.880 16 204 1.8E-44 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS00260 edbf77761c359d5502470282fe3a52c5 330 Gene3D G3DSA:1.10.10.60 277 324 1.9E-4 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00260 edbf77761c359d5502470282fe3a52c5 330 Gene3D G3DSA:1.10.10.60 218 276 1.0E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00260 edbf77761c359d5502470282fe3a52c5 330 PANTHER PTHR11019 10 330 4.5E-121 T 23-04-2016 DC74_RS33970 c4267d0fa111af047dd5f5fe29761f04 139 PANTHER PTHR36222 1 137 1.6E-47 T 23-04-2016 DC74_RS33970 c4267d0fa111af047dd5f5fe29761f04 139 SUPERFAMILY SSF103196 6 127 2.96E-35 T 23-04-2016 DC74_RS33970 c4267d0fa111af047dd5f5fe29761f04 139 SMART SM00960 8 98 4.4E-31 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS33970 c4267d0fa111af047dd5f5fe29761f04 139 Pfam PF03259 Roadblock/LC7 domain 7 98 9.4E-28 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS33970 c4267d0fa111af047dd5f5fe29761f04 139 Gene3D G3DSA:3.30.450.30 7 123 5.7E-27 T 23-04-2016 DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 Pfam PF00580 UvrD/REP helicase N-terminal domain 72 352 2.6E-76 T 23-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 PANTHER PTHR11070:SF7 320 598 2.7E-230 T 23-04-2016 DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 PANTHER PTHR11070:SF7 634 756 2.7E-230 T 23-04-2016 DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 PANTHER PTHR11070:SF7 67 304 2.7E-230 T 23-04-2016 DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 Gene3D G3DSA:3.40.50.300 661 752 2.1E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 Gene3D G3DSA:3.40.50.300 367 469 2.1E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 PANTHER PTHR11070 320 598 2.7E-230 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 PANTHER PTHR11070 634 756 2.7E-230 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 PANTHER PTHR11070 67 304 2.7E-230 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 Gene3D G3DSA:1.10.10.160 176 253 5.7E-23 T 23-04-2016 IPR013986 DExx box DNA helicase domain DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 Gene3D G3DSA:3.40.50.300 68 172 1.5E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 Gene3D G3DSA:3.40.50.300 254 366 1.5E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 Pfam PF13361 UvrD-like helicase C-terminal domain 358 724 1.9E-66 T 23-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 68 857 0.0 T 23-04-2016 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 SUPERFAMILY SSF52540 68 751 2.29E-176 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24365 5dd5478419ee807f61e2a478745e0045 859 Gene3D G3DSA:1.10.486.10 470 646 1.5E-47 T 23-04-2016 DC74_RS25130 320d06b5467b64b440f2a48184f5a5ac 529 SUPERFAMILY SSF52096 13 264 9.63E-82 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS25130 320d06b5467b64b440f2a48184f5a5ac 529 Pfam PF01039 Carboxyl transferase domain 36 527 1.0E-193 T 23-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 DC74_RS25130 320d06b5467b64b440f2a48184f5a5ac 529 SUPERFAMILY SSF52096 251 529 2.17E-88 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS25130 320d06b5467b64b440f2a48184f5a5ac 529 Gene3D G3DSA:3.90.226.10 277 529 1.6E-99 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS25130 320d06b5467b64b440f2a48184f5a5ac 529 PANTHER PTHR22855 1 529 0.0 T 23-04-2016 DC74_RS25130 320d06b5467b64b440f2a48184f5a5ac 529 PANTHER PTHR22855:SF14 1 529 0.0 T 23-04-2016 DC74_RS25130 320d06b5467b64b440f2a48184f5a5ac 529 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 137 155 7.7E-6 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 DC74_RS25130 320d06b5467b64b440f2a48184f5a5ac 529 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 103 117 7.7E-6 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 DC74_RS25130 320d06b5467b64b440f2a48184f5a5ac 529 Gene3D G3DSA:3.90.226.10 5 264 1.7E-85 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS05845 b99584552abde4d874755fe2ae9bab1d 485 Gene3D G3DSA:1.20.1250.20 249 454 3.0E-17 T 23-04-2016 DC74_RS05845 b99584552abde4d874755fe2ae9bab1d 485 Pfam PF07690 Major Facilitator Superfamily 11 214 2.3E-26 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS05845 b99584552abde4d874755fe2ae9bab1d 485 Pfam PF07690 Major Facilitator Superfamily 262 465 1.1E-12 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS05845 b99584552abde4d874755fe2ae9bab1d 485 PANTHER PTHR23501:SF7 2 451 5.3E-108 T 23-04-2016 DC74_RS05845 b99584552abde4d874755fe2ae9bab1d 485 PANTHER PTHR23501 2 451 5.3E-108 T 23-04-2016 DC74_RS05845 b99584552abde4d874755fe2ae9bab1d 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 130 154 5.2E-5 T 23-04-2016 DC74_RS05845 b99584552abde4d874755fe2ae9bab1d 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 100 120 5.2E-5 T 23-04-2016 DC74_RS05845 b99584552abde4d874755fe2ae9bab1d 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 9 33 5.2E-5 T 23-04-2016 DC74_RS05845 b99584552abde4d874755fe2ae9bab1d 485 SUPERFAMILY SSF103473 239 454 4.32E-53 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05845 b99584552abde4d874755fe2ae9bab1d 485 SUPERFAMILY SSF103473 2 189 4.32E-53 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05845 b99584552abde4d874755fe2ae9bab1d 485 Gene3D G3DSA:1.20.1250.20 7 180 8.3E-20 T 23-04-2016 DC74_RS18200 95ab6caeb425a59f2933dce6e7bdbf03 316 Pfam PF00296 Luciferase-like monooxygenase 33 249 2.8E-52 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS18200 95ab6caeb425a59f2933dce6e7bdbf03 316 Gene3D G3DSA:3.20.20.30 7 315 3.9E-73 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS18200 95ab6caeb425a59f2933dce6e7bdbf03 316 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 40 289 7.2E-71 T 23-04-2016 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted DC74_RS18200 95ab6caeb425a59f2933dce6e7bdbf03 316 SUPERFAMILY SSF51679 26 315 8.64E-66 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS18200 95ab6caeb425a59f2933dce6e7bdbf03 316 PANTHER PTHR30011 24 252 9.5E-47 T 23-04-2016 DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 PANTHER PTHR21021 268 561 2.6E-63 T 23-04-2016 DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 SMART SM00065 152 318 0.0017 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 SUPERFAMILY SSF55781 184 320 8.72E-14 T 23-04-2016 IPR029016 GAF domain-like DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 365 552 9.9E-48 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 Pfam PF13185 GAF domain 183 308 1.1E-12 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 SUPERFAMILY SSF55785 31 134 4.19E-13 T 23-04-2016 IPR000014 PAS domain DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 SMART SM00331 336 552 1.0E-39 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 Gene3D G3DSA:3.30.450.40 147 319 3.8E-13 T 23-04-2016 IPR029016 GAF domain-like DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 Pfam PF08447 PAS fold 43 130 4.6E-12 T 23-04-2016 IPR013655 PAS fold-3 GO:0005515 DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 SMART SM00086 94 136 1.6E-5 T 23-04-2016 IPR001610 PAC motif DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 PANTHER PTHR21021:SF19 268 561 2.6E-63 T 23-04-2016 DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 Gene3D G3DSA:3.30.565.10 578 684 1.4E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 Gene3D G3DSA:3.60.40.10 478 550 1.2E-7 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 Gene3D G3DSA:3.30.450.20 30 132 1.2E-13 T 23-04-2016 DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 SUPERFAMILY SSF55874 593 684 6.27E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 Pfam PF13581 Histidine kinase-like ATPase domain 570 681 3.9E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33470 a6e2f844f40fa49e4b6d66e7172b9f1f 687 SUPERFAMILY SSF81606 350 551 2.62E-12 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS33580 26beeb017966380deaa8790f14ab2aab 263 Gene3D G3DSA:3.20.20.70 19 260 9.2E-67 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS33580 26beeb017966380deaa8790f14ab2aab 263 PANTHER PTHR21139:SF2 12 262 5.6E-74 T 23-04-2016 DC74_RS33580 26beeb017966380deaa8790f14ab2aab 263 Pfam PF00121 Triosephosphate isomerase 22 249 5.7E-49 T 23-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 DC74_RS33580 26beeb017966380deaa8790f14ab2aab 263 SUPERFAMILY SSF51351 15 259 1.03E-57 T 23-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 DC74_RS33580 26beeb017966380deaa8790f14ab2aab 263 PANTHER PTHR21139 12 262 5.6E-74 T 23-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 DC74_RS31650 6d10c049ceba9177d5364df8d7bd379b 468 Pfam PF01979 Amidohydrolase family 57 443 7.3E-27 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS31650 6d10c049ceba9177d5364df8d7bd379b 468 SUPERFAMILY SSF51556 61 389 6.81E-104 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS31650 6d10c049ceba9177d5364df8d7bd379b 468 SUPERFAMILY SSF51338 2 82 5.4E-11 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS31650 6d10c049ceba9177d5364df8d7bd379b 468 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 5 461 3.3E-167 T 23-04-2016 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: REACT_18266 DC74_RS31650 6d10c049ceba9177d5364df8d7bd379b 468 PANTHER PTHR11647:SF1 1 461 4.4E-199 T 23-04-2016 DC74_RS31650 6d10c049ceba9177d5364df8d7bd379b 468 SUPERFAMILY SSF51338 360 462 1.49E-34 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS31650 6d10c049ceba9177d5364df8d7bd379b 468 Gene3D G3DSA:2.30.40.10 3 75 1.0E-25 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS31650 6d10c049ceba9177d5364df8d7bd379b 468 PANTHER PTHR11647 1 461 4.4E-199 T 23-04-2016 DC74_RS31650 6d10c049ceba9177d5364df8d7bd379b 468 Gene3D G3DSA:2.30.40.10 384 461 4.1E-13 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS31650 6d10c049ceba9177d5364df8d7bd379b 468 Gene3D G3DSA:3.20.20.140 76 383 3.4E-114 T 23-04-2016 DC74_RS35230 9f5b3f55517d9ce8071a3d16fd6d1320 338 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 107 325 1.4E-41 T 23-04-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 DC74_RS35230 9f5b3f55517d9ce8071a3d16fd6d1320 338 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 9 93 4.8E-13 T 23-04-2016 DC74_RS35230 9f5b3f55517d9ce8071a3d16fd6d1320 338 Gene3D G3DSA:2.60.120.200 10 93 7.4E-16 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS35230 9f5b3f55517d9ce8071a3d16fd6d1320 338 SUPERFAMILY SSF49899 15 93 4.3E-10 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS35230 9f5b3f55517d9ce8071a3d16fd6d1320 338 PANTHER PTHR23344 100 336 1.7E-63 T 23-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 DC74_RS35230 9f5b3f55517d9ce8071a3d16fd6d1320 338 Gene3D G3DSA:3.20.20.190 102 332 5.5E-68 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS35230 9f5b3f55517d9ce8071a3d16fd6d1320 338 SUPERFAMILY SSF51695 104 331 6.02E-67 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS06655 1349ded149fd8d3a763f20d84f7f40d8 223 SMART SM00895 81 202 2.2E-21 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS06655 1349ded149fd8d3a763f20d84f7f40d8 223 SUPERFAMILY SSF48008 80 208 7.32E-29 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS06655 1349ded149fd8d3a763f20d84f7f40d8 223 Pfam PF07729 FCD domain 81 202 4.4E-27 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS06655 1349ded149fd8d3a763f20d84f7f40d8 223 Gene3D G3DSA:1.20.120.530 79 211 1.8E-33 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS06655 1349ded149fd8d3a763f20d84f7f40d8 223 PANTHER PTHR11751 2 98 4.9E-25 T 23-04-2016 DC74_RS06655 1349ded149fd8d3a763f20d84f7f40d8 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 63 8.2E-18 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS06655 1349ded149fd8d3a763f20d84f7f40d8 223 Gene3D G3DSA:1.10.10.10 2 66 2.4E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06655 1349ded149fd8d3a763f20d84f7f40d8 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 23 37 8.4E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS06655 1349ded149fd8d3a763f20d84f7f40d8 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 53 8.4E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS06655 1349ded149fd8d3a763f20d84f7f40d8 223 SMART SM00345 4 63 2.9E-20 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS06655 1349ded149fd8d3a763f20d84f7f40d8 223 SUPERFAMILY SSF46785 2 67 4.21E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06550 bfafca2caada82ef776f8a8a333d7356 343 PANTHER PTHR30024:SF8 35 300 1.9E-28 T 23-04-2016 DC74_RS06550 bfafca2caada82ef776f8a8a333d7356 343 Pfam PF09084 NMT1/THI5 like 58 268 1.8E-20 T 23-04-2016 IPR015168 SsuA/THI5-like DC74_RS06550 bfafca2caada82ef776f8a8a333d7356 343 PANTHER PTHR30024 35 300 1.9E-28 T 23-04-2016 DC74_RS06550 bfafca2caada82ef776f8a8a333d7356 343 SUPERFAMILY SSF53850 41 286 2.64E-33 T 23-04-2016 DC74_RS06550 bfafca2caada82ef776f8a8a333d7356 343 Gene3D G3DSA:3.40.190.10 126 257 6.6E-14 T 23-04-2016 DC74_RS32880 dfc94ac81fe1fe169fa1c16ba5ba0bfe 133 Pfam PF09350 Domain of unknown function (DUF1992) 14 79 7.7E-19 T 23-04-2016 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 2.6E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 2.6E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 2.6E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 204 7.0E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 Gene3D G3DSA:3.40.50.2300 2 155 6.0E-23 T 23-04-2016 DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 SUPERFAMILY SSF46894 155 204 8.5E-12 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 SMART SM00421 155 212 2.4E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 PANTHER PTHR26402 1 215 2.4E-55 T 23-04-2016 DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 SUPERFAMILY SSF52172 2 171 7.46E-17 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 SMART SM00448 1 127 2.9E-9 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 PANTHER PTHR26402:SF582 1 215 2.4E-55 T 23-04-2016 DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 Pfam PF00072 Response regulator receiver domain 3 115 1.1E-14 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS39535 5d3282ca02d914acbcdb64fea9fc08e6 221 Gene3D G3DSA:1.10.10.10 156 219 1.0E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23695 b0f78e5a95a768e410079cfb4234c9a7 127 Gene3D G3DSA:2.40.50.140 3 64 4.1E-24 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS23695 b0f78e5a95a768e410079cfb4234c9a7 127 PANTHER PTHR11544 2 124 1.8E-38 T 23-04-2016 DC74_RS23695 b0f78e5a95a768e410079cfb4234c9a7 127 PRINTS PR00050 Cold shock protein signature 24 33 1.8E-13 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS23695 b0f78e5a95a768e410079cfb4234c9a7 127 PRINTS PR00050 Cold shock protein signature 4 19 1.8E-13 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS23695 b0f78e5a95a768e410079cfb4234c9a7 127 PRINTS PR00050 Cold shock protein signature 38 56 1.8E-13 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS23695 b0f78e5a95a768e410079cfb4234c9a7 127 Pfam PF00313 'Cold-shock' DNA-binding domain 3 63 1.3E-20 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS23695 b0f78e5a95a768e410079cfb4234c9a7 127 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 23-04-2016 IPR019844 Cold-shock conserved site DC74_RS23695 b0f78e5a95a768e410079cfb4234c9a7 127 PANTHER PTHR11544:SF43 2 124 1.8E-38 T 23-04-2016 DC74_RS23695 b0f78e5a95a768e410079cfb4234c9a7 127 SMART SM00357 3 65 1.4E-20 T 23-04-2016 IPR011129 Cold shock protein GO:0003676 DC74_RS23695 b0f78e5a95a768e410079cfb4234c9a7 127 SUPERFAMILY SSF50249 2 68 5.63E-19 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS08130 cefa49397480262250134c716cfc649c 831 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 384 510 3.3E-12 T 23-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS08130 cefa49397480262250134c716cfc649c 831 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 640 740 7.0E-5 T 23-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS08130 cefa49397480262250134c716cfc649c 831 Gene3D G3DSA:2.160.10.10 237 366 3.1E-26 T 23-04-2016 DC74_RS08130 cefa49397480262250134c716cfc649c 831 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 532 632 1.2E-16 T 23-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS08130 cefa49397480262250134c716cfc649c 831 Gene3D G3DSA:3.40.120.10 552 628 6.0E-12 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS08130 cefa49397480262250134c716cfc649c 831 SUPERFAMILY SSF53738 637 741 3.92E-11 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS08130 cefa49397480262250134c716cfc649c 831 SUPERFAMILY SSF55957 744 828 2.62E-12 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS08130 cefa49397480262250134c716cfc649c 831 Gene3D G3DSA:3.40.120.10 633 726 3.3E-13 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS08130 cefa49397480262250134c716cfc649c 831 Gene3D G3DSA:3.90.550.10 1 236 6.9E-76 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS08130 cefa49397480262250134c716cfc649c 831 Pfam PF00483 Nucleotidyl transferase 2 233 8.3E-54 T 23-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 DC74_RS08130 cefa49397480262250134c716cfc649c 831 SUPERFAMILY SSF53738 530 634 3.14E-14 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS08130 cefa49397480262250134c716cfc649c 831 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 268 301 5.3E-4 T 23-04-2016 IPR001451 Hexapeptide repeat DC74_RS08130 cefa49397480262250134c716cfc649c 831 SUPERFAMILY SSF53448 269 325 2.82E-80 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS08130 cefa49397480262250134c716cfc649c 831 SUPERFAMILY SSF53448 1 237 2.82E-80 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS08130 cefa49397480262250134c716cfc649c 831 SUPERFAMILY SSF51161 243 433 2.14E-32 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS08130 cefa49397480262250134c716cfc649c 831 PANTHER PTHR22572:SF95 2 422 3.0E-169 T 23-04-2016 DC74_RS08130 cefa49397480262250134c716cfc649c 831 PANTHER PTHR22572 2 422 3.0E-169 T 23-04-2016 DC74_RS08130 cefa49397480262250134c716cfc649c 831 Gene3D G3DSA:3.30.310.50 750 827 3.3E-12 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS08130 cefa49397480262250134c716cfc649c 831 Gene3D G3DSA:3.40.120.10 384 508 2.0E-11 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DC74_RS27020 43aa424c238765107737af41eeb566e4 143 PANTHER PTHR24095:SF137 28 139 2.7E-12 T 23-04-2016 DC74_RS27020 43aa424c238765107737af41eeb566e4 143 SMART SM00823 Phosphopantetheine attachment site 56 125 3.9E-4 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS27020 43aa424c238765107737af41eeb566e4 143 PANTHER PTHR24095 28 139 2.7E-12 T 23-04-2016 DC74_RS27020 43aa424c238765107737af41eeb566e4 143 SUPERFAMILY SSF47336 53 121 1.31E-16 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS27020 43aa424c238765107737af41eeb566e4 143 Pfam PF00550 Phosphopantetheine attachment site 58 121 8.4E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS27020 43aa424c238765107737af41eeb566e4 143 Gene3D G3DSA:1.10.1200.10 51 123 1.2E-20 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS07810 cde1508bf27c38b5c4f4e3b0c97e947f 134 Gene3D G3DSA:3.10.180.10 3 132 7.6E-18 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS07810 cde1508bf27c38b5c4f4e3b0c97e947f 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 131 3.5E-6 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS07810 cde1508bf27c38b5c4f4e3b0c97e947f 134 SUPERFAMILY SSF54593 6 134 3.44E-18 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS31430 75b8d96ad4da1a37a64d02d5ff17d295 446 Gene3D G3DSA:3.20.20.140 72 394 2.9E-131 T 23-04-2016 DC74_RS31430 75b8d96ad4da1a37a64d02d5ff17d295 446 PANTHER PTHR11647 1 445 5.8E-220 T 23-04-2016 DC74_RS31430 75b8d96ad4da1a37a64d02d5ff17d295 446 SUPERFAMILY SSF51338 5 57 4.32E-23 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS31430 75b8d96ad4da1a37a64d02d5ff17d295 446 SUPERFAMILY SSF51338 373 431 4.32E-23 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS31430 75b8d96ad4da1a37a64d02d5ff17d295 446 SUPERFAMILY SSF51556 58 374 1.22E-100 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS31430 75b8d96ad4da1a37a64d02d5ff17d295 446 Gene3D G3DSA:2.30.40.10 6 71 2.6E-16 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS31430 75b8d96ad4da1a37a64d02d5ff17d295 446 PANTHER PTHR11647:SF4 1 445 5.8E-220 T 23-04-2016 DC74_RS31430 75b8d96ad4da1a37a64d02d5ff17d295 446 TIGRFAM TIGR03178 allantoinase: allantoinase 5 443 1.1E-188 T 23-04-2016 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698|UniPathway: UPA00395 DC74_RS31430 75b8d96ad4da1a37a64d02d5ff17d295 446 Pfam PF01979 Amidohydrolase family 54 425 2.3E-29 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS10730 bd33ce7de67f751e695b49def7b21e04 451 Gene3D G3DSA:2.60.120.10 299 419 4.4E-66 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS10730 bd33ce7de67f751e695b49def7b21e04 451 Gene3D G3DSA:2.60.120.10 213 238 4.4E-66 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS10730 bd33ce7de67f751e695b49def7b21e04 451 Pfam PF04209 homogentisate 1,2-dioxygenase 18 449 4.7E-208 T 23-04-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 DC74_RS10730 bd33ce7de67f751e695b49def7b21e04 451 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 17 451 70.815 T 23-04-2016 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 DC74_RS10730 bd33ce7de67f751e695b49def7b21e04 451 SUPERFAMILY SSF51182 16 451 8.15E-162 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS10730 bd33ce7de67f751e695b49def7b21e04 451 PANTHER PTHR11056 4 451 9.5E-250 T 23-04-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 DC74_RS10730 bd33ce7de67f751e695b49def7b21e04 451 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 16 449 3.0E-213 T 23-04-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 DC74_RS00100 10f3182b040e63ad4548a6e624dbbce0 487 Hamap MF_01983 UbiD-like decarboxylase. 3 486 44.874 T 23-04-2016 IPR032903 UbiD-like decarboxylase/ferulic acid decarboxylase 1 DC74_RS00100 10f3182b040e63ad4548a6e624dbbce0 487 PANTHER PTHR30108 3 486 1.3E-114 T 23-04-2016 DC74_RS00100 10f3182b040e63ad4548a6e624dbbce0 487 Gene3D G3DSA:3.40.1670.10 331 454 1.7E-11 T 23-04-2016 DC74_RS00100 10f3182b040e63ad4548a6e624dbbce0 487 SUPERFAMILY SSF143968 315 486 9.02E-27 T 23-04-2016 DC74_RS00100 10f3182b040e63ad4548a6e624dbbce0 487 SUPERFAMILY SSF50475 5 313 2.35E-88 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS00100 10f3182b040e63ad4548a6e624dbbce0 487 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 421 6.1E-109 T 23-04-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 DC74_RS00100 10f3182b040e63ad4548a6e624dbbce0 487 PANTHER PTHR30108:SF1 3 486 1.3E-114 T 23-04-2016 DC74_RS00100 10f3182b040e63ad4548a6e624dbbce0 487 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 7 430 4.8E-92 T 23-04-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 DC74_RS03100 4383b29e798bc68c52c219fe0a0a58ad 288 PANTHER PTHR35797 38 259 1.4E-14 T 23-04-2016 DC74_RS03100 4383b29e798bc68c52c219fe0a0a58ad 288 Pfam PF02517 CAAX protease self-immunity 117 217 3.1E-13 T 23-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 DC74_RS03100 4383b29e798bc68c52c219fe0a0a58ad 288 PANTHER PTHR35797:SF1 38 259 1.4E-14 T 23-04-2016 DC74_RS11495 2527cdb16b36753e6ddc1db36f0a65d2 246 PANTHER PTHR34135:SF2 11 235 1.0E-61 T 23-04-2016 DC74_RS11495 2527cdb16b36753e6ddc1db36f0a65d2 246 Pfam PF01183 Glycosyl hydrolases family 25 44 228 1.4E-48 T 23-04-2016 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 DC74_RS11495 2527cdb16b36753e6ddc1db36f0a65d2 246 PANTHER PTHR34135 11 235 1.0E-61 T 23-04-2016 DC74_RS11495 2527cdb16b36753e6ddc1db36f0a65d2 246 Gene3D G3DSA:3.20.20.80 41 245 1.6E-67 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS11495 2527cdb16b36753e6ddc1db36f0a65d2 246 SMART SM00641 40 151 1.7E-28 T 23-04-2016 IPR018077 Glycoside hydrolase, family 25 subgroup DC74_RS11495 2527cdb16b36753e6ddc1db36f0a65d2 246 SUPERFAMILY SSF51445 41 245 3.02E-58 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS10140 84b958a9d400fc014207d8ed46988202 430 Gene3D G3DSA:3.40.50.1000 231 292 4.0E-7 T 23-04-2016 IPR023214 HAD-like domain DC74_RS10140 84b958a9d400fc014207d8ed46988202 430 SUPERFAMILY SSF56784 185 296 2.5E-9 T 23-04-2016 IPR023214 HAD-like domain DC74_RS10140 84b958a9d400fc014207d8ed46988202 430 SUPERFAMILY SSF56784 79 94 2.5E-9 T 23-04-2016 IPR023214 HAD-like domain DC74_RS16180 0efa62a230a3c04d688245dafff8926f 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 251 2.5E-13 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16180 0efa62a230a3c04d688245dafff8926f 265 PANTHER PTHR30183 7 265 8.9E-53 T 23-04-2016 DC74_RS16180 0efa62a230a3c04d688245dafff8926f 265 PANTHER PTHR30183:SF3 7 265 8.9E-53 T 23-04-2016 DC74_RS16180 0efa62a230a3c04d688245dafff8926f 265 Gene3D G3DSA:1.10.3720.10 9 264 8.3E-41 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16180 0efa62a230a3c04d688245dafff8926f 265 SUPERFAMILY SSF161098 17 253 1.83E-43 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS25155 b2870ed55ce4cd8378fe145ec3a168c2 514 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 5 508 43.356 T 23-04-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 DC74_RS25155 b2870ed55ce4cd8378fe145ec3a168c2 514 Gene3D G3DSA:1.20.200.10 201 510 4.7E-115 T 23-04-2016 DC74_RS25155 b2870ed55ce4cd8378fe145ec3a168c2 514 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 6 507 2.0E-210 T 23-04-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 DC74_RS25155 b2870ed55ce4cd8378fe145ec3a168c2 514 PANTHER PTHR10362 5 502 5.8E-215 T 23-04-2016 DC74_RS25155 b2870ed55ce4cd8378fe145ec3a168c2 514 SUPERFAMILY SSF48557 4 504 1.49E-178 T 23-04-2016 IPR008948 L-Aspartase-like GO:0003824 DC74_RS25155 b2870ed55ce4cd8378fe145ec3a168c2 514 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 141 157 - T 23-04-2016 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 DC74_RS25155 b2870ed55ce4cd8378fe145ec3a168c2 514 Gene3D G3DSA:1.10.275.10 3 200 5.6E-74 T 23-04-2016 IPR024083 Fumarase/histidase, N-terminal DC74_RS25155 b2870ed55ce4cd8378fe145ec3a168c2 514 PANTHER PTHR10362:SF7 5 502 5.8E-215 T 23-04-2016 DC74_RS25155 b2870ed55ce4cd8378fe145ec3a168c2 514 Pfam PF00221 Aromatic amino acid lyase 14 474 5.2E-182 T 23-04-2016 IPR001106 Aromatic amino acid lyase DC74_RS37680 48d4f86b042e043619651e9a4d21e0e0 332 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 304 2.8E-71 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS37680 48d4f86b042e043619651e9a4d21e0e0 332 PANTHER PTHR10314:SF104 7 321 1.7E-144 T 23-04-2016 DC74_RS37680 48d4f86b042e043619651e9a4d21e0e0 332 Gene3D G3DSA:3.40.50.1100 153 321 9.0E-65 T 23-04-2016 DC74_RS37680 48d4f86b042e043619651e9a4d21e0e0 332 Gene3D G3DSA:3.40.50.1100 2 42 9.0E-65 T 23-04-2016 DC74_RS37680 48d4f86b042e043619651e9a4d21e0e0 332 SUPERFAMILY SSF53686 2 322 5.89E-95 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS37680 48d4f86b042e043619651e9a4d21e0e0 332 Gene3D G3DSA:3.40.50.1100 43 147 2.7E-39 T 23-04-2016 DC74_RS37680 48d4f86b042e043619651e9a4d21e0e0 332 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 23-04-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 DC74_RS37680 48d4f86b042e043619651e9a4d21e0e0 332 ProSitePatterns PS00217 Sugar transport proteins signature 2. 177 202 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS37680 48d4f86b042e043619651e9a4d21e0e0 332 PANTHER PTHR10314 7 321 1.7E-144 T 23-04-2016 DC74_RS38975 51a8e9033e2ff153aa44195ccc856ba1 381 PANTHER PTHR13794 1 381 1.1E-128 T 23-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 DC74_RS38975 51a8e9033e2ff153aa44195ccc856ba1 381 Gene3D G3DSA:3.30.390.10 12 113 6.1E-46 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS38975 51a8e9033e2ff153aa44195ccc856ba1 381 Pfam PF13378 Enolase C-terminal domain-like 129 354 3.8E-53 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS38975 51a8e9033e2ff153aa44195ccc856ba1 381 PANTHER PTHR13794:SF4 1 381 1.1E-128 T 23-04-2016 DC74_RS38975 51a8e9033e2ff153aa44195ccc856ba1 381 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 23-04-2016 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 DC74_RS38975 51a8e9033e2ff153aa44195ccc856ba1 381 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 23-04-2016 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 DC74_RS38975 51a8e9033e2ff153aa44195ccc856ba1 381 SUPERFAMILY SSF54826 2 112 3.84E-31 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS38975 51a8e9033e2ff153aa44195ccc856ba1 381 SMART SM00922 125 230 1.6E-14 T 23-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DC74_RS38975 51a8e9033e2ff153aa44195ccc856ba1 381 Gene3D G3DSA:3.20.20.120 114 348 4.7E-74 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS38975 51a8e9033e2ff153aa44195ccc856ba1 381 SUPERFAMILY SSF51604 95 358 2.58E-68 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS38975 51a8e9033e2ff153aa44195ccc856ba1 381 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 107 2.0E-24 T 23-04-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain DC74_RS17085 b0d288064039f3848d08b76292cb534d 370 Gene3D G3DSA:3.20.20.70 18 231 3.5E-25 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS17085 b0d288064039f3848d08b76292cb534d 370 Pfam PF04055 Radical SAM superfamily 23 167 8.5E-12 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS17085 b0d288064039f3848d08b76292cb534d 370 SUPERFAMILY SSF102114 74 231 6.15E-22 T 23-04-2016 DC74_RS17085 b0d288064039f3848d08b76292cb534d 370 SUPERFAMILY SSF102114 17 45 6.15E-22 T 23-04-2016 DC74_RS33300 cda8395066c9c64e73dabb04560b5164 319 SUPERFAMILY SSF52047 111 290 6.02E-11 T 23-04-2016 DC74_RS33300 cda8395066c9c64e73dabb04560b5164 319 Gene3D G3DSA:3.80.10.10 36 297 7.3E-63 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like DC74_RS33300 cda8395066c9c64e73dabb04560b5164 319 Pfam PF13516 Leucine Rich repeat 240 258 0.039 T 23-04-2016 IPR001611 Leucine-rich repeat GO:0005515 DC74_RS27900 f1a85062ba7a227bc72a95bab0875ea5 239 Pfam PF09339 IclR helix-turn-helix domain 10 57 1.5E-9 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS27900 f1a85062ba7a227bc72a95bab0875ea5 239 SMART SM00346 7 93 1.0E-14 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS27900 f1a85062ba7a227bc72a95bab0875ea5 239 SUPERFAMILY SSF55781 62 234 5.76E-34 T 23-04-2016 IPR029016 GAF domain-like DC74_RS27900 f1a85062ba7a227bc72a95bab0875ea5 239 PANTHER PTHR30136:SF18 1 237 2.6E-146 T 23-04-2016 DC74_RS27900 f1a85062ba7a227bc72a95bab0875ea5 239 Pfam PF01614 Bacterial transcriptional regulator 125 231 2.8E-16 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS27900 f1a85062ba7a227bc72a95bab0875ea5 239 Gene3D G3DSA:1.10.10.10 3 73 3.4E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27900 f1a85062ba7a227bc72a95bab0875ea5 239 PANTHER PTHR30136 1 237 2.6E-146 T 23-04-2016 DC74_RS27900 f1a85062ba7a227bc72a95bab0875ea5 239 SUPERFAMILY SSF46785 7 75 2.18E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27900 f1a85062ba7a227bc72a95bab0875ea5 239 Gene3D G3DSA:3.30.450.40 74 234 7.2E-40 T 23-04-2016 IPR029016 GAF domain-like DC74_RS33210 4a3c9ae97c436602b37823f9d740eb3c 288 Pfam PF00494 Squalene/phytoene synthase 5 273 1.8E-66 T 23-04-2016 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 DC74_RS33210 4a3c9ae97c436602b37823f9d740eb3c 288 SUPERFAMILY SSF48576 6 286 1.11E-59 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS33210 4a3c9ae97c436602b37823f9d740eb3c 288 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 3 283 1.6E-95 T 23-04-2016 IPR017827 Squalene synthase HpnC DC74_RS33210 4a3c9ae97c436602b37823f9d740eb3c 288 PANTHER PTHR31480:SF8 2 287 8.1E-121 T 23-04-2016 DC74_RS33210 4a3c9ae97c436602b37823f9d740eb3c 288 PANTHER PTHR31480 2 287 8.1E-121 T 23-04-2016 DC74_RS33210 4a3c9ae97c436602b37823f9d740eb3c 288 Gene3D G3DSA:1.10.600.10 8 277 4.2E-50 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS21750 03f63ddf5a4c1b1c543604a7b7a013bd 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 1.1E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS21750 03f63ddf5a4c1b1c543604a7b7a013bd 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 1.1E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS21750 03f63ddf5a4c1b1c543604a7b7a013bd 194 SUPERFAMILY SSF46689 2 69 3.85E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS21750 03f63ddf5a4c1b1c543604a7b7a013bd 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 50 4.6E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS21750 03f63ddf5a4c1b1c543604a7b7a013bd 194 PANTHER PTHR30055 2 194 6.5E-30 T 23-04-2016 DC74_RS21750 03f63ddf5a4c1b1c543604a7b7a013bd 194 Gene3D G3DSA:1.10.357.10 2 179 1.7E-31 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS21750 03f63ddf5a4c1b1c543604a7b7a013bd 194 SUPERFAMILY SSF48498 82 185 1.41E-16 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS21750 03f63ddf5a4c1b1c543604a7b7a013bd 194 PANTHER PTHR30055:SF47 2 194 6.5E-30 T 23-04-2016 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00359 B-class P450 signature 220 242 1.9E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00359 B-class P450 signature 166 182 1.9E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00359 B-class P450 signature 299 310 1.9E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00359 B-class P450 signature 367 376 1.9E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00359 B-class P450 signature 317 344 1.9E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00359 B-class P450 signature 183 198 1.9E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00359 B-class P450 signature 376 387 1.9E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00359 B-class P450 signature 345 360 1.9E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00359 B-class P450 signature 116 127 1.9E-52 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PANTHER PTHR11712 3 428 3.9E-79 T 23-04-2016 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00385 P450 superfamily signature 264 281 6.6E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00385 P450 superfamily signature 376 387 6.6E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00385 P450 superfamily signature 299 310 6.6E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 PRINTS PR00385 P450 superfamily signature 367 376 6.6E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 Pfam PF00067 Cytochrome P450 72 227 5.2E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 Pfam PF00067 Cytochrome P450 243 397 1.4E-21 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 SUPERFAMILY SSF48264 46 427 9.82E-89 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 369 378 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS26820 bd84902cf8dc6f6f39cd2a02aac9e6e1 429 Gene3D G3DSA:1.10.630.10 35 428 1.4E-108 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01165 615a63b0a577d2b5ee96322ab741978a 235 PIRSF PIRSF036990 4 226 8.5E-57 T 23-04-2016 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON DC74_RS01165 615a63b0a577d2b5ee96322ab741978a 235 Gene3D G3DSA:3.10.580.10 5 143 3.0E-31 T 23-04-2016 DC74_RS01165 615a63b0a577d2b5ee96322ab741978a 235 SMART SM00116 13 61 4.3E-6 T 23-04-2016 IPR000644 CBS domain DC74_RS01165 615a63b0a577d2b5ee96322ab741978a 235 SMART SM00116 95 143 5.3E-10 T 23-04-2016 IPR000644 CBS domain DC74_RS01165 615a63b0a577d2b5ee96322ab741978a 235 Pfam PF04972 BON domain 146 210 3.0E-7 T 23-04-2016 IPR007055 BON domain DC74_RS01165 615a63b0a577d2b5ee96322ab741978a 235 Pfam PF00571 CBS domain 6 60 1.5E-12 T 23-04-2016 IPR000644 CBS domain DC74_RS01165 615a63b0a577d2b5ee96322ab741978a 235 Pfam PF00571 CBS domain 88 142 5.0E-15 T 23-04-2016 IPR000644 CBS domain DC74_RS01165 615a63b0a577d2b5ee96322ab741978a 235 SUPERFAMILY SSF54631 2 144 5.94E-33 T 23-04-2016 DC74_RS06900 b836abde6d2af7e952ffdcac0f71285c 406 Pfam PF07730 Histidine kinase 187 252 1.0E-14 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS06900 b836abde6d2af7e952ffdcac0f71285c 406 SMART SM00387 297 397 6.0E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06900 b836abde6d2af7e952ffdcac0f71285c 406 SUPERFAMILY SSF55874 290 390 6.19E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06900 b836abde6d2af7e952ffdcac0f71285c 406 PANTHER PTHR24421:SF26 69 406 7.0E-57 T 23-04-2016 DC74_RS06900 b836abde6d2af7e952ffdcac0f71285c 406 Gene3D G3DSA:3.30.565.10 285 391 2.5E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06900 b836abde6d2af7e952ffdcac0f71285c 406 PANTHER PTHR24421 69 406 7.0E-57 T 23-04-2016 DC74_RS21565 face40f2cdb32451d5ce90a6b5089875 374 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 84 207 9.3E-30 T 23-04-2016 DC74_RS21565 face40f2cdb32451d5ce90a6b5089875 374 Gene3D G3DSA:3.40.50.150 7 249 4.1E-51 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS21565 face40f2cdb32451d5ce90a6b5089875 374 PANTHER PTHR11579:SF0 1 35 5.0E-40 T 23-04-2016 DC74_RS21565 face40f2cdb32451d5ce90a6b5089875 374 PANTHER PTHR11579:SF0 67 247 5.0E-40 T 23-04-2016 DC74_RS21565 face40f2cdb32451d5ce90a6b5089875 374 PANTHER PTHR11579 1 35 5.0E-40 T 23-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 DC74_RS21565 face40f2cdb32451d5ce90a6b5089875 374 PANTHER PTHR11579 67 247 5.0E-40 T 23-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 DC74_RS21565 face40f2cdb32451d5ce90a6b5089875 374 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 160 175 - T 23-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 DC74_RS21565 face40f2cdb32451d5ce90a6b5089875 374 SUPERFAMILY SSF53335 87 210 1.64E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS11755 72e338370a6ea2104be8dc1fde767861 331 PANTHER PTHR35457 1 319 4.9E-46 T 23-04-2016 DC74_RS11755 72e338370a6ea2104be8dc1fde767861 331 PANTHER PTHR35457:SF1 1 319 4.9E-46 T 23-04-2016 DC74_RS11755 72e338370a6ea2104be8dc1fde767861 331 Pfam PF02628 Cytochrome oxidase assembly protein 25 67 6.6E-10 T 23-04-2016 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 UniPathway: UPA00269 DC74_RS11755 72e338370a6ea2104be8dc1fde767861 331 Pfam PF02628 Cytochrome oxidase assembly protein 74 198 5.9E-9 T 23-04-2016 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 UniPathway: UPA00269 DC74_RS23880 6aac385b5221a6f6fd16c5460d15daae 538 SUPERFAMILY SSF56801 25 533 2.62E-152 T 23-04-2016 DC74_RS23880 6aac385b5221a6f6fd16c5460d15daae 538 Gene3D G3DSA:2.30.38.10 353 429 2.9E-28 T 23-04-2016 DC74_RS23880 6aac385b5221a6f6fd16c5460d15daae 538 Gene3D G3DSA:3.30.300.30 435 534 2.0E-32 T 23-04-2016 DC74_RS23880 6aac385b5221a6f6fd16c5460d15daae 538 Pfam PF00501 AMP-binding enzyme 38 438 5.2E-100 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS23880 6aac385b5221a6f6fd16c5460d15daae 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 522 2.0E-17 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS23880 6aac385b5221a6f6fd16c5460d15daae 538 PANTHER PTHR24096 12 531 3.3E-207 T 23-04-2016 DC74_RS23880 6aac385b5221a6f6fd16c5460d15daae 538 Gene3D G3DSA:3.40.50.980 29 194 4.5E-33 T 23-04-2016 DC74_RS23880 6aac385b5221a6f6fd16c5460d15daae 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS23880 6aac385b5221a6f6fd16c5460d15daae 538 Gene3D G3DSA:3.40.50.980 195 349 2.1E-49 T 23-04-2016 DC74_RS12465 d1b302c4d5311152d90bb8cb976f0be7 205 Gene3D G3DSA:3.40.50.1820 9 199 5.9E-28 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS12465 d1b302c4d5311152d90bb8cb976f0be7 205 Pfam PF01738 Dienelactone hydrolase family 6 199 8.0E-22 T 23-04-2016 IPR002925 Dienelactone hydrolase GO:0016787 DC74_RS12465 d1b302c4d5311152d90bb8cb976f0be7 205 PANTHER PTHR22946 15 201 4.0E-34 T 23-04-2016 DC74_RS12465 d1b302c4d5311152d90bb8cb976f0be7 205 SUPERFAMILY SSF53474 7 199 1.25E-28 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS13385 3c8562947baad41ced5736a71c3c6ddb 227 SMART SM00345 10 69 2.0E-19 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS13385 3c8562947baad41ced5736a71c3c6ddb 227 SUPERFAMILY SSF48008 95 226 1.91E-29 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS13385 3c8562947baad41ced5736a71c3c6ddb 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 5.4E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS13385 3c8562947baad41ced5736a71c3c6ddb 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 5.4E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS13385 3c8562947baad41ced5736a71c3c6ddb 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 5.0E-19 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS13385 3c8562947baad41ced5736a71c3c6ddb 227 Pfam PF07729 FCD domain 98 219 7.9E-28 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS13385 3c8562947baad41ced5736a71c3c6ddb 227 SUPERFAMILY SSF46785 4 82 9.31E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13385 3c8562947baad41ced5736a71c3c6ddb 227 PANTHER PTHR11751 4 76 7.6E-20 T 23-04-2016 DC74_RS13385 3c8562947baad41ced5736a71c3c6ddb 227 PANTHER PTHR11751 96 115 7.6E-20 T 23-04-2016 DC74_RS13385 3c8562947baad41ced5736a71c3c6ddb 227 SMART SM00895 98 220 1.2E-20 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS13385 3c8562947baad41ced5736a71c3c6ddb 227 Gene3D G3DSA:1.10.10.10 4 71 1.8E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13385 3c8562947baad41ced5736a71c3c6ddb 227 Gene3D G3DSA:1.20.120.530 95 226 3.6E-32 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS26655 81ef7baa581346b0d328bd94a2ced63d 69 Gene3D G3DSA:1.10.10.60 37 64 3.3E-6 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS26655 81ef7baa581346b0d328bd94a2ced63d 69 SUPERFAMILY SSF88659 42 66 3.99E-5 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS26655 81ef7baa581346b0d328bd94a2ced63d 69 Pfam PF13384 Homeodomain-like domain 41 63 8.1E-6 T 23-04-2016 DC74_RS22255 4a590c77ed32dcad64568d76389071ef 201 PANTHER PTHR30055 3 194 7.4E-26 T 23-04-2016 DC74_RS22255 4a590c77ed32dcad64568d76389071ef 201 SUPERFAMILY SSF48498 89 194 1.68E-8 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS22255 4a590c77ed32dcad64568d76389071ef 201 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS22255 4a590c77ed32dcad64568d76389071ef 201 SUPERFAMILY SSF46689 8 80 1.7E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS22255 4a590c77ed32dcad64568d76389071ef 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.04E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS22255 4a590c77ed32dcad64568d76389071ef 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.04E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS22255 4a590c77ed32dcad64568d76389071ef 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 60 6.0E-18 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS22255 4a590c77ed32dcad64568d76389071ef 201 Gene3D G3DSA:1.10.357.10 6 194 6.0E-39 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS22090 251243f910934acd0e5ef421491c6237 781 SUPERFAMILY SSF53056 531 771 6.54E-50 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS22090 251243f910934acd0e5ef421491c6237 781 PANTHER PTHR11814:SF123 39 621 6.4E-174 T 23-04-2016 DC74_RS22090 251243f910934acd0e5ef421491c6237 781 Pfam PF00484 Carbonic anhydrase 589 757 2.7E-41 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS22090 251243f910934acd0e5ef421491c6237 781 Pfam PF00916 Sulfate permease family 42 398 6.1E-61 T 23-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 DC74_RS22090 251243f910934acd0e5ef421491c6237 781 SMART SM00947 581 763 2.6E-52 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS22090 251243f910934acd0e5ef421491c6237 781 PANTHER PTHR11814 39 621 6.4E-174 T 23-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 DC74_RS22090 251243f910934acd0e5ef421491c6237 781 Gene3D G3DSA:3.40.1050.10 550 774 6.7E-77 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 SUPERFAMILY SSF52743 626 646 1.31E-48 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 SUPERFAMILY SSF52743 254 596 1.31E-48 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 PANTHER PTHR14218:SF15 618 642 5.6E-53 T 23-04-2016 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 PANTHER PTHR14218:SF15 62 217 5.6E-53 T 23-04-2016 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 PANTHER PTHR14218:SF15 471 592 5.6E-53 T 23-04-2016 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 PANTHER PTHR14218:SF15 237 453 5.6E-53 T 23-04-2016 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 PANTHER PTHR14218 618 642 5.6E-53 T 23-04-2016 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 PANTHER PTHR14218 62 217 5.6E-53 T 23-04-2016 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 PANTHER PTHR14218 471 592 5.6E-53 T 23-04-2016 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 PANTHER PTHR14218 237 453 5.6E-53 T 23-04-2016 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 SMART SM00944 55 194 7.5E-47 T 23-04-2016 IPR015366 Peptidase S53, propeptide GO:0008236 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 Pfam PF09286 Pro-kumamolisin, activation domain 59 193 1.1E-29 T 23-04-2016 IPR015366 Peptidase S53, propeptide GO:0008236 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 Gene3D G3DSA:3.40.50.200 243 644 1.0E-76 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 SUPERFAMILY SSF54897 44 209 3.06E-40 T 23-04-2016 IPR009020 Proteinase inhibitor, propeptide DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 Pfam PF00082 Subtilase family 315 563 1.8E-13 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS15125 4f5b055dcb998df1d2af1dd37238b1ea 652 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 543 553 - T 23-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site DC74_RS13930 1975611be7256189c2054d7624804919 379 Pfam PF04332 Protein of unknown function (DUF475) 44 362 5.0E-132 T 23-04-2016 IPR007427 Protein of unknown function DUF475 DC74_RS13930 1975611be7256189c2054d7624804919 379 PANTHER PTHR30238 111 158 4.9E-149 T 23-04-2016 DC74_RS13930 1975611be7256189c2054d7624804919 379 PANTHER PTHR30238 2 86 4.9E-149 T 23-04-2016 DC74_RS13930 1975611be7256189c2054d7624804919 379 PANTHER PTHR30238:SF3 212 372 4.9E-149 T 23-04-2016 DC74_RS13930 1975611be7256189c2054d7624804919 379 PANTHER PTHR30238:SF3 111 158 4.9E-149 T 23-04-2016 DC74_RS13930 1975611be7256189c2054d7624804919 379 PANTHER PTHR30238:SF3 2 86 4.9E-149 T 23-04-2016 DC74_RS13930 1975611be7256189c2054d7624804919 379 PANTHER PTHR30238 212 372 4.9E-149 T 23-04-2016 DC74_RS14080 4652aed2d84baae1b856a06a77547b17 216 PANTHER PTHR22935 1 201 2.0E-42 T 23-04-2016 DC74_RS14080 4652aed2d84baae1b856a06a77547b17 216 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 17 208 23.602 T 23-04-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 DC74_RS14080 4652aed2d84baae1b856a06a77547b17 216 SUPERFAMILY SSF55166 14 206 1.45E-46 T 23-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain DC74_RS14080 4652aed2d84baae1b856a06a77547b17 216 PIRSF PIRSF026671 1 214 8.7E-47 T 23-04-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 DC74_RS14080 4652aed2d84baae1b856a06a77547b17 216 Pfam PF01427 D-ala-D-ala dipeptidase 57 203 4.5E-20 T 23-04-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 DC74_RS14080 4652aed2d84baae1b856a06a77547b17 216 PANTHER PTHR22935:SF73 1 201 2.0E-42 T 23-04-2016 DC74_RS14080 4652aed2d84baae1b856a06a77547b17 216 Gene3D G3DSA:3.30.1380.10 14 209 2.4E-51 T 23-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain DC74_RS21355 1d5d54be9a96e6cc9352fa0718729687 345 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 243 313 4.2E-21 T 23-04-2016 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal DC74_RS21355 1d5d54be9a96e6cc9352fa0718729687 345 PANTHER PTHR13078:SF52 105 314 4.6E-36 T 23-04-2016 DC74_RS21355 1d5d54be9a96e6cc9352fa0718729687 345 PANTHER PTHR13078 105 314 4.6E-36 T 23-04-2016 DC74_RS21355 1d5d54be9a96e6cc9352fa0718729687 345 PANTHER PTHR13078 38 86 4.6E-36 T 23-04-2016 DC74_RS21355 1d5d54be9a96e6cc9352fa0718729687 345 PANTHER PTHR13078:SF52 38 86 4.6E-36 T 23-04-2016 DC74_RS21355 1d5d54be9a96e6cc9352fa0718729687 345 SUPERFAMILY SSF50249 191 322 3.77E-33 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS21355 1d5d54be9a96e6cc9352fa0718729687 345 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 205 241 1.5E-6 T 23-04-2016 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DC74_RS21355 1d5d54be9a96e6cc9352fa0718729687 345 SUPERFAMILY SSF54637 41 174 5.69E-14 T 23-04-2016 IPR029069 HotDog domain DC74_RS21355 1d5d54be9a96e6cc9352fa0718729687 345 Gene3D G3DSA:3.10.129.10 36 168 4.9E-10 T 23-04-2016 IPR029069 HotDog domain DC74_RS21355 1d5d54be9a96e6cc9352fa0718729687 345 Pfam PF13452 N-terminal half of MaoC dehydratase 37 161 5.9E-15 T 23-04-2016 DC74_RS35130 a5a40293c82ffe1b25331799a0084a13 254 Gene3D G3DSA:3.90.226.10 2 226 3.2E-55 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS35130 a5a40293c82ffe1b25331799a0084a13 254 PANTHER PTHR11941 1 223 1.1E-48 T 23-04-2016 DC74_RS35130 a5a40293c82ffe1b25331799a0084a13 254 SUPERFAMILY SSF52096 2 243 3.62E-55 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS35130 a5a40293c82ffe1b25331799a0084a13 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 248 1.9E-36 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS35130 a5a40293c82ffe1b25331799a0084a13 254 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 107 127 - T 23-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 2.9E-68 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 23-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 PIRSF PIRSF002133 1 123 8.4E-55 T 23-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 SUPERFAMILY SSF50249 2 123 6.77E-53 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 Pfam PF00164 Ribosomal protein S12/S23 3 123 1.5E-44 T 23-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 Gene3D G3DSA:2.40.50.140 2 123 3.3E-65 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 8.38E-59 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 8.38E-59 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 8.38E-59 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 8.38E-59 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 8.38E-59 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 8.38E-59 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.977 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 DC74_RS18760 a0e41c2799cf2c613b8f5763b914b45c 123 PANTHER PTHR11652 2 116 7.0E-75 T 23-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS39250 bfbab93f08b9920407ba9151ecb2bddd 212 PANTHER PTHR30086:SF3 2 206 2.7E-47 T 23-04-2016 DC74_RS39250 bfbab93f08b9920407ba9151ecb2bddd 212 PANTHER PTHR30086 2 206 2.7E-47 T 23-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 DC74_RS39250 bfbab93f08b9920407ba9151ecb2bddd 212 PIRSF PIRSF006324 1 210 3.1E-51 T 23-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 DC74_RS39250 bfbab93f08b9920407ba9151ecb2bddd 212 Pfam PF01810 LysE type translocator 17 206 2.5E-25 T 23-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 DC74_RS26325 dd75c695b899a1986841531fcaa9981d 264 PANTHER PTHR20854:SF38 1 262 6.4E-94 T 23-04-2016 DC74_RS26325 dd75c695b899a1986841531fcaa9981d 264 Pfam PF00459 Inositol monophosphatase family 10 261 2.7E-47 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS26325 dd75c695b899a1986841531fcaa9981d 264 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 8 262 6.9E-90 T 23-04-2016 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15|UniPathway: UPA00031 DC74_RS26325 dd75c695b899a1986841531fcaa9981d 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 9.5E-13 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS26325 dd75c695b899a1986841531fcaa9981d 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 9.5E-13 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS26325 dd75c695b899a1986841531fcaa9981d 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 9.5E-13 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS26325 dd75c695b899a1986841531fcaa9981d 264 Gene3D G3DSA:3.40.190.80 158 263 4.6E-23 T 23-04-2016 DC74_RS26325 dd75c695b899a1986841531fcaa9981d 264 PANTHER PTHR20854 1 262 6.4E-94 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS26325 dd75c695b899a1986841531fcaa9981d 264 Gene3D G3DSA:3.30.540.10 3 157 5.4E-43 T 23-04-2016 DC74_RS26325 dd75c695b899a1986841531fcaa9981d 264 SUPERFAMILY SSF56655 3 263 2.62E-74 T 23-04-2016 DC74_RS26325 dd75c695b899a1986841531fcaa9981d 264 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 23-04-2016 IPR020583 Inositol monophosphatase, metal-binding site DC74_RS12790 e8206911c0c2a20817e46e3f5abfad3e 598 SUPERFAMILY SSF56801 17 288 7.98E-115 T 23-04-2016 DC74_RS12790 e8206911c0c2a20817e46e3f5abfad3e 598 SUPERFAMILY SSF56801 337 596 7.98E-115 T 23-04-2016 DC74_RS12790 e8206911c0c2a20817e46e3f5abfad3e 598 Gene3D G3DSA:3.30.300.30 464 515 9.9E-5 T 23-04-2016 DC74_RS12790 e8206911c0c2a20817e46e3f5abfad3e 598 PANTHER PTHR24096:SF193 5 597 1.3E-207 T 23-04-2016 DC74_RS12790 e8206911c0c2a20817e46e3f5abfad3e 598 Gene3D G3DSA:2.30.38.10 397 457 4.0E-20 T 23-04-2016 DC74_RS12790 e8206911c0c2a20817e46e3f5abfad3e 598 Pfam PF00501 AMP-binding enzyme 23 466 1.6E-100 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS12790 e8206911c0c2a20817e46e3f5abfad3e 598 PANTHER PTHR24096 5 597 1.3E-207 T 23-04-2016 DC74_RS12790 e8206911c0c2a20817e46e3f5abfad3e 598 Gene3D G3DSA:3.40.50.980 334 396 5.1E-26 T 23-04-2016 DC74_RS12790 e8206911c0c2a20817e46e3f5abfad3e 598 Gene3D G3DSA:3.40.50.980 190 283 5.1E-26 T 23-04-2016 DC74_RS12790 e8206911c0c2a20817e46e3f5abfad3e 598 Gene3D G3DSA:3.40.50.980 17 189 3.9E-36 T 23-04-2016 DC74_RS12790 e8206911c0c2a20817e46e3f5abfad3e 598 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 PANTHER PTHR30385:SF4 1 262 1.0E-95 T 23-04-2016 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 Pfam PF04545 Sigma-70, region 4 215 262 1.2E-15 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 Gene3D G3DSA:1.10.10.10 206 263 3.3E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 Pfam PF04542 Sigma-70 region 2 49 118 1.6E-18 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 SUPERFAMILY SSF88659 201 264 1.25E-14 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 43 264 1.2E-87 T 23-04-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 Gene3D G3DSA:1.10.10.10 119 172 1.9E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 Pfam PF04539 Sigma-70 region 3 128 201 1.0E-13 T 23-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 SUPERFAMILY SSF88946 20 119 1.11E-30 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 Gene3D G3DSA:1.10.601.10 40 118 8.3E-26 T 23-04-2016 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 PRINTS PR00046 Major sigma-70 factor signature 218 230 5.1E-8 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 PRINTS PR00046 Major sigma-70 factor signature 73 86 5.1E-8 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 PRINTS PR00046 Major sigma-70 factor signature 235 250 5.1E-8 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 PANTHER PTHR30385 1 262 1.0E-95 T 23-04-2016 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 46 263 2.2E-33 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 73 86 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21590 51fb0dc1f281e15e547b17e52265612a 269 SUPERFAMILY SSF88659 122 195 7.41E-13 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 PIRSF PIRSF001438 1 338 5.5E-106 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 8 327 33.812 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 9 216 7.3E-65 T 23-04-2016 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 SUPERFAMILY SSF53850 8 222 9.42E-63 T 23-04-2016 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 Gene3D G3DSA:3.30.160.40 226 334 4.5E-20 T 23-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 236 252 - T 23-04-2016 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 PANTHER PTHR11557:SF0 1 335 8.9E-106 T 23-04-2016 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 PANTHER PTHR11557 1 335 8.9E-106 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 Gene3D G3DSA:3.40.190.10 6 111 6.3E-37 T 23-04-2016 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 Gene3D G3DSA:3.40.190.10 112 204 1.1E-31 T 23-04-2016 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 232 325 3.2E-12 T 23-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 9 258 3.5E-82 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 SUPERFAMILY SSF54782 225 335 7.45E-15 T 23-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 PRINTS PR00151 Porphobilinogen deaminase signature 46 66 2.8E-18 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 PRINTS PR00151 Porphobilinogen deaminase signature 235 252 2.8E-18 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 PRINTS PR00151 Porphobilinogen deaminase signature 77 96 2.8E-18 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19440 5888d9e03f1c8d475c0603236b2c6dcc 338 PRINTS PR00151 Porphobilinogen deaminase signature 148 165 2.8E-18 T 23-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS10215 a35c17caa4dcbdc1f66f30942591995a 304 PANTHER PTHR10133:SF27 1 291 6.7E-93 T 23-04-2016 DC74_RS10215 a35c17caa4dcbdc1f66f30942591995a 304 Gene3D G3DSA:1.10.150.20 179 237 3.7E-19 T 23-04-2016 DC74_RS10215 a35c17caa4dcbdc1f66f30942591995a 304 SUPERFAMILY SSF47807 186 297 1.94E-21 T 23-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 DC74_RS10215 a35c17caa4dcbdc1f66f30942591995a 304 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 1 180 2.4E-47 T 23-04-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 DC74_RS10215 a35c17caa4dcbdc1f66f30942591995a 304 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 186 276 3.5E-19 T 23-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 DC74_RS10215 a35c17caa4dcbdc1f66f30942591995a 304 Gene3D G3DSA:3.40.50.1010 1 178 1.8E-47 T 23-04-2016 IPR029060 PIN domain-like DC74_RS10215 a35c17caa4dcbdc1f66f30942591995a 304 PANTHER PTHR10133 1 291 6.7E-93 T 23-04-2016 DC74_RS10215 a35c17caa4dcbdc1f66f30942591995a 304 SMART SM00279 183 218 1.7E-10 T 23-04-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 DC74_RS10215 a35c17caa4dcbdc1f66f30942591995a 304 SUPERFAMILY SSF88723 1 163 4.91E-38 T 23-04-2016 IPR029060 PIN domain-like DC74_RS10215 a35c17caa4dcbdc1f66f30942591995a 304 SMART SM00475 1 273 4.1E-79 T 23-04-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 536 1.8E-141 T 23-04-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|UniPathway: UPA00134 DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 PANTHER PTHR11772:SF7 2 401 8.7E-188 T 23-04-2016 DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 PANTHER PTHR11772:SF7 445 538 8.7E-188 T 23-04-2016 DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 SUPERFAMILY SSF52402 453 569 4.63E-58 T 23-04-2016 DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 SUPERFAMILY SSF52402 219 397 4.63E-58 T 23-04-2016 DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 Gene3D G3DSA:3.60.20.10 1 222 3.7E-74 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 PIRSF PIRSF001589 1 606 5.2E-140 T 23-04-2016 DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 Pfam PF00733 Asparagine synthase 240 579 1.3E-79 T 23-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 Gene3D G3DSA:3.40.50.620 223 395 1.1E-71 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 Gene3D G3DSA:3.40.50.620 431 599 1.1E-71 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 Pfam PF13537 Glutamine amidotransferase domain 48 168 3.4E-45 T 23-04-2016 IPR017932 Glutamine amidotransferase type 2 domain DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 PANTHER PTHR11772 2 401 8.7E-188 T 23-04-2016 DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 PANTHER PTHR11772 445 538 8.7E-188 T 23-04-2016 DC74_RS05055 d459b5b9b5ae7e68edc2d1c7755c5e79 608 SUPERFAMILY SSF56235 1 224 5.32E-64 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 PANTHER PTHR33303 60 668 2.7E-223 T 23-04-2016 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 PANTHER PTHR33303 712 941 2.7E-223 T 23-04-2016 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 Pfam PF13380 CoA binding domain 214 344 4.7E-14 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 SUPERFAMILY SSF55729 23 175 1.53E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 SUPERFAMILY SSF52210 342 506 2.88E-29 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 Gene3D G3DSA:3.40.630.30 18 183 3.1E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 Gene3D G3DSA:3.40.50.720 197 339 3.9E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 SMART SM00881 209 310 1.3E-21 T 23-04-2016 IPR003781 CoA-binding GO:0048037 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 SUPERFAMILY SSF52210 505 621 4.71E-10 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 SUPERFAMILY SSF56059 748 935 1.73E-18 T 23-04-2016 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 Pfam PF00583 Acetyltransferase (GNAT) family 84 168 9.1E-11 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 Gene3D G3DSA:3.40.50.261 507 617 6.8E-5 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 PANTHER PTHR33303:SF3 60 668 2.7E-223 T 23-04-2016 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 PANTHER PTHR33303:SF3 712 941 2.7E-223 T 23-04-2016 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 Gene3D G3DSA:3.40.50.261 340 501 7.7E-29 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 364 502 4.8E-37 T 23-04-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 Pfam PF13549 ATP-grasp domain 757 940 4.0E-47 T 23-04-2016 DC74_RS29080 5648dfd04be4009db02f20cb530576ea 957 SUPERFAMILY SSF51735 207 339 1.73E-27 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36710 67f2e8a0477e9cd245e4b1b417057038 390 SUPERFAMILY SSF51905 2 169 2.21E-56 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS36710 67f2e8a0477e9cd245e4b1b417057038 390 SUPERFAMILY SSF51905 277 355 2.21E-56 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS36710 67f2e8a0477e9cd245e4b1b417057038 390 Gene3D G3DSA:3.50.50.60 2 174 1.1E-36 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS36710 67f2e8a0477e9cd245e4b1b417057038 390 Gene3D G3DSA:3.50.50.60 269 349 1.1E-36 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS36710 67f2e8a0477e9cd245e4b1b417057038 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.4E-20 T 23-04-2016 DC74_RS36710 67f2e8a0477e9cd245e4b1b417057038 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.4E-20 T 23-04-2016 DC74_RS36710 67f2e8a0477e9cd245e4b1b417057038 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 1.4E-20 T 23-04-2016 DC74_RS36710 67f2e8a0477e9cd245e4b1b417057038 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 1.4E-20 T 23-04-2016 DC74_RS36710 67f2e8a0477e9cd245e4b1b417057038 390 PANTHER PTHR13789 1 350 2.6E-68 T 23-04-2016 DC74_RS36710 67f2e8a0477e9cd245e4b1b417057038 390 Pfam PF01494 FAD binding domain 2 339 1.7E-26 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 SUPERFAMILY SSF51735 4 197 3.67E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 PANTHER PTHR11374:SF18 3 447 7.7E-202 T 23-04-2016 DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 328 429 2.9E-24 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 PIRSF PIRSF500134 3 447 4.6E-151 T 23-04-2016 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|UniPathway: UPA00038 DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 Gene3D G3DSA:1.20.5.100 213 238 1.3E-16 T 23-04-2016 DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 SUPERFAMILY SSF48179 209 308 4.42E-26 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 PIRSF PIRSF000124 3 444 5.4E-114 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 192 4.1E-57 T 23-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 425 2.9E-123 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 PANTHER PTHR11374 3 447 7.7E-202 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 Gene3D G3DSA:3.40.50.720 4 212 7.5E-70 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 210 303 4.1E-30 T 23-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 Gene3D G3DSA:3.40.50.720 242 445 3.1E-64 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 SMART SM00984 328 429 1.7E-41 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS17130 1859a187a79a3b0bcaa4cc255f3a8cd6 447 SUPERFAMILY SSF52413 322 439 5.23E-32 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS14645 a1c880e7d06e40867911c007c9114d62 322 Gene3D G3DSA:2.40.10.10 121 214 9.2E-7 T 23-04-2016 DC74_RS14645 a1c880e7d06e40867911c007c9114d62 322 SUPERFAMILY SSF50494 107 295 1.79E-14 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS14210 aac538de92cb5dfcf2ff1190a8dd3e12 291 PANTHER PTHR22916 10 240 5.5E-25 T 23-04-2016 DC74_RS14210 aac538de92cb5dfcf2ff1190a8dd3e12 291 Gene3D G3DSA:3.90.550.10 10 224 1.2E-21 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS14210 aac538de92cb5dfcf2ff1190a8dd3e12 291 SUPERFAMILY SSF53448 6 219 1.64E-36 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS14210 aac538de92cb5dfcf2ff1190a8dd3e12 291 Pfam PF13641 Glycosyltransferase like family 2 12 201 1.4E-9 T 23-04-2016 DC74_RS35520 1a533448ce219d43462bc3bbc77e6e33 266 Gene3D G3DSA:3.10.310.10 131 263 4.2E-28 T 23-04-2016 DC74_RS35520 1a533448ce219d43462bc3bbc77e6e33 266 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 233 4.2E-26 T 23-04-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- DC74_RS35520 1a533448ce219d43462bc3bbc77e6e33 266 SUPERFAMILY SSF54506 2 265 8.17E-51 T 23-04-2016 DC74_RS35520 1a533448ce219d43462bc3bbc77e6e33 266 PIRSF PIRSF016184 1 264 9.7E-34 T 23-04-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- DC74_RS35520 1a533448ce219d43462bc3bbc77e6e33 266 Gene3D G3DSA:3.10.310.10 2 130 1.7E-30 T 23-04-2016 DC74_RS35520 1a533448ce219d43462bc3bbc77e6e33 266 Pfam PF02567 Phenazine biosynthesis-like protein 7 265 5.1E-41 T 23-04-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- DC74_RS35520 1a533448ce219d43462bc3bbc77e6e33 266 PANTHER PTHR13774 1 265 6.8E-63 T 23-04-2016 DC74_RS35520 1a533448ce219d43462bc3bbc77e6e33 266 PANTHER PTHR13774:SF17 1 265 6.8E-63 T 23-04-2016 DC74_RS02280 42c528957e383e59ad357d4ae71fbd4c 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 62 5.1E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS02280 42c528957e383e59ad357d4ae71fbd4c 212 PANTHER PTHR30055 1 171 2.6E-24 T 23-04-2016 DC74_RS02280 42c528957e383e59ad357d4ae71fbd4c 212 Gene3D G3DSA:1.10.357.10 5 203 4.9E-31 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS02280 42c528957e383e59ad357d4ae71fbd4c 212 SUPERFAMILY SSF46689 4 84 2.46E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02280 42c528957e383e59ad357d4ae71fbd4c 212 PANTHER PTHR30055:SF73 1 171 2.6E-24 T 23-04-2016 DC74_RS10460 fc7f2ead1ec332d9e9a2031847f341d1 287 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 29 287 6.9E-105 T 23-04-2016 IPR022292 Conserved hypothetical protein CHP03843 DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 SUPERFAMILY SSF51905 416 463 5.93E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 SUPERFAMILY SSF51905 39 287 5.93E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 Pfam PF02910 Fumarate reductase flavoprotein C-term 513 647 7.7E-36 T 23-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 PANTHER PTHR11632 12 647 0.0 T 23-04-2016 DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 Gene3D G3DSA:1.20.58.100 487 602 9.7E-32 T 23-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 Pfam PF00890 FAD binding domain 46 451 5.2E-61 T 23-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 46 65 1.1E-6 T 23-04-2016 DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 415 437 1.1E-6 T 23-04-2016 DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 SUPERFAMILY SSF56425 271 413 4.49E-34 T 23-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 Gene3D G3DSA:3.90.700.10 277 406 9.4E-19 T 23-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 PANTHER PTHR11632:SF53 12 647 0.0 T 23-04-2016 DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 SUPERFAMILY SSF46977 504 647 7.46E-40 T 23-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 Gene3D G3DSA:3.50.50.60 36 276 8.4E-77 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 Gene3D G3DSA:3.50.50.60 408 460 8.4E-77 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12350 947e12fd3e30b141895c80f16b63ebae 648 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 46 647 0.0 T 23-04-2016 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|UniPathway: UPA00223 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 Gene3D G3DSA:3.40.50.720 4 179 2.2E-67 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 SUPERFAMILY SSF51735 3 180 5.29E-54 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 188 209 - T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 159 1.1E-52 T 23-04-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 180 317 4.3E-49 T 23-04-2016 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 PANTHER PTHR11728 3 332 1.8E-146 T 23-04-2016 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 238 255 1.0E-45 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 1.0E-45 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 1.0E-45 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 1.0E-45 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 198 222 1.0E-45 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 173 197 1.0E-45 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 Gene3D G3DSA:1.10.1040.10 180 326 4.0E-54 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 322 37.476 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 SUPERFAMILY SSF48179 179 331 4.25E-54 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS27940 1965f910fedfe20fb123f961f8db8e19 333 PIRSF PIRSF000114 1 332 1.3E-100 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 DC74_RS19150 67802417650052df01f0279ff5a19f28 397 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 271 281 - T 23-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site DC74_RS19150 67802417650052df01f0279ff5a19f28 397 SUPERFAMILY SSF52743 34 329 6.15E-72 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS19150 67802417650052df01f0279ff5a19f28 397 Pfam PF00082 Subtilase family 57 320 1.3E-44 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS19150 67802417650052df01f0279ff5a19f28 397 Gene3D G3DSA:3.40.50.200 30 328 2.0E-74 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS19150 67802417650052df01f0279ff5a19f28 397 PRINTS PR00723 Subtilisin serine protease family (S8) signature 57 76 6.9E-18 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS19150 67802417650052df01f0279ff5a19f28 397 PRINTS PR00723 Subtilisin serine protease family (S8) signature 109 122 6.9E-18 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS19150 67802417650052df01f0279ff5a19f28 397 PRINTS PR00723 Subtilisin serine protease family (S8) signature 270 286 6.9E-18 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS19150 67802417650052df01f0279ff5a19f28 397 PANTHER PTHR10795 26 329 3.2E-57 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS19150 67802417650052df01f0279ff5a19f28 397 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 62 73 - T 23-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site DC74_RS19150 67802417650052df01f0279ff5a19f28 397 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 54 397 5.5E-96 T 23-04-2016 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 DC74_RS19150 67802417650052df01f0279ff5a19f28 397 PANTHER PTHR10795:SF419 26 329 3.2E-57 T 23-04-2016 DC74_RS19150 67802417650052df01f0279ff5a19f28 397 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 113 123 - T 23-04-2016 IPR022398 Peptidase S8, subtilisin, His-active site DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 SUPERFAMILY SSF51735 8 218 3.22E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 Pfam PF00106 short chain dehydrogenase 6 187 1.6E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 58 69 3.1E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 3.1E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 3.1E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 127 3.1E-15 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 58 69 4.2E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 117 125 4.2E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 4.2E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 PANTHER PTHR24322:SF622 20 121 1.7E-48 T 23-04-2016 DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 PANTHER PTHR24322 20 121 1.7E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 PANTHER PTHR24322:SF622 147 177 1.7E-48 T 23-04-2016 DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 PANTHER PTHR24322 147 177 1.7E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS06470 0ea445e016971e144ca2049a9539daca 222 Gene3D G3DSA:3.40.50.720 9 218 4.3E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS35895 f0292af66e647a6f74b5e227c2f54196 374 PIRSF PIRSF005622 1 364 4.0E-157 T 23-04-2016 IPR002780 Hydrogenase formation HypD protein GO:0046872 DC74_RS35895 f0292af66e647a6f74b5e227c2f54196 374 PANTHER PTHR30149:SF0 2 370 6.6E-199 T 23-04-2016 DC74_RS35895 f0292af66e647a6f74b5e227c2f54196 374 PANTHER PTHR30149 2 370 6.6E-199 T 23-04-2016 DC74_RS35895 f0292af66e647a6f74b5e227c2f54196 374 Pfam PF01924 Hydrogenase formation hypA family 12 359 1.5E-153 T 23-04-2016 IPR002780 Hydrogenase formation HypD protein GO:0046872 DC74_RS35895 f0292af66e647a6f74b5e227c2f54196 374 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 5 361 4.3E-146 T 23-04-2016 IPR002780 Hydrogenase formation HypD protein GO:0046872 DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 Gene3D G3DSA:1.10.1740.10 326 426 3.6E-25 T 23-04-2016 DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 Pfam PF13288 DXP reductoisomerase C-terminal domain 285 420 1.5E-29 T 23-04-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 25 157 3.8E-40 T 23-04-2016 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 SUPERFAMILY SSF55347 151 287 1.01E-54 T 23-04-2016 DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 Gene3D G3DSA:3.40.50.720 21 173 9.5E-54 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 169 252 9.6E-37 T 23-04-2016 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 25 425 43.992 T 23-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 SUPERFAMILY SSF69055 316 425 9.29E-20 T 23-04-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 24 376 1.5E-111 T 23-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 PANTHER PTHR30525 1 391 5.1E-196 T 23-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 PANTHER PTHR30525 407 436 5.1E-196 T 23-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 SUPERFAMILY SSF51735 22 173 1.46E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS28380 9464b291a614e1723d1984aef0be2619 438 PIRSF PIRSF006205 22 432 5.1E-137 T 23-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS39680 61ffbe033d24d09d47cdffe14cb04c7d 99 Gene3D G3DSA:1.10.10.10 1 91 3.3E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39680 61ffbe033d24d09d47cdffe14cb04c7d 99 PRINTS PR00598 Bacterial regulatory protein MarR family signature 1 17 3.0E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS39680 61ffbe033d24d09d47cdffe14cb04c7d 99 PRINTS PR00598 Bacterial regulatory protein MarR family signature 18 33 3.0E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS39680 61ffbe033d24d09d47cdffe14cb04c7d 99 PRINTS PR00598 Bacterial regulatory protein MarR family signature 37 53 3.0E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS39680 61ffbe033d24d09d47cdffe14cb04c7d 99 PANTHER PTHR33164 1 98 1.7E-16 T 23-04-2016 DC74_RS39680 61ffbe033d24d09d47cdffe14cb04c7d 99 SUPERFAMILY SSF46785 1 90 5.04E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39680 61ffbe033d24d09d47cdffe14cb04c7d 99 Pfam PF01047 MarR family 1 41 2.7E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS39680 61ffbe033d24d09d47cdffe14cb04c7d 99 SMART SM00347 1 76 8.7E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 288 298 4.4E-21 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 269 4.4E-21 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 354 366 4.4E-21 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 404 420 4.4E-21 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 460 477 4.4E-21 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 Gene3D G3DSA:1.10.940.10 19 182 1.0E-45 T 23-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 SUPERFAMILY SSF53335 171 477 6.43E-49 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 353 364 - T 23-04-2016 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 Pfam PF01029 NusB family 23 147 4.6E-24 T 23-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 SUPERFAMILY SSF48013 23 181 3.27E-33 T 23-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 Gene3D G3DSA:3.40.50.150 265 477 6.6E-42 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 PANTHER PTHR22807 34 477 1.2E-90 T 23-04-2016 DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 Pfam PF01189 16S rRNA methyltransferase RsmB/F 284 476 4.7E-43 T 23-04-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 DC74_RS09375 727b229dd5e9d19be1140a5f48b8c740 479 PANTHER PTHR22807:SF30 34 477 1.2E-90 T 23-04-2016 DC74_RS27870 44533a5409f68c8ca9d70e37a5ee7119 241 PANTHER PTHR12725 1 233 4.9E-40 T 23-04-2016 DC74_RS27870 44533a5409f68c8ca9d70e37a5ee7119 241 Gene3D G3DSA:3.40.50.1000 2 226 9.8E-40 T 23-04-2016 IPR023214 HAD-like domain DC74_RS27870 44533a5409f68c8ca9d70e37a5ee7119 241 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 119 196 2.6E-10 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS27870 44533a5409f68c8ca9d70e37a5ee7119 241 Pfam PF13419 Haloacid dehalogenase-like hydrolase 77 201 1.5E-17 T 23-04-2016 IPR023214 HAD-like domain DC74_RS27870 44533a5409f68c8ca9d70e37a5ee7119 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 2.6E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS27870 44533a5409f68c8ca9d70e37a5ee7119 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 191 204 2.6E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS27870 44533a5409f68c8ca9d70e37a5ee7119 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 2.6E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS27870 44533a5409f68c8ca9d70e37a5ee7119 241 SUPERFAMILY SSF56784 1 225 4.58E-43 T 23-04-2016 IPR023214 HAD-like domain DC74_RS27870 44533a5409f68c8ca9d70e37a5ee7119 241 PANTHER PTHR12725:SF65 1 233 4.9E-40 T 23-04-2016 DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 SUPERFAMILY SSF56235 1 214 3.0E-38 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 SUPERFAMILY SSF52402 446 544 8.38E-40 T 23-04-2016 DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 SUPERFAMILY SSF52402 239 381 8.38E-40 T 23-04-2016 DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 Pfam PF13537 Glutamine amidotransferase domain 49 166 4.4E-28 T 23-04-2016 IPR017932 Glutamine amidotransferase type 2 domain DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 PIRSF PIRSF001589 1 586 2.5E-90 T 23-04-2016 DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 Pfam PF00733 Asparagine synthase 240 585 8.0E-45 T 23-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 Gene3D G3DSA:3.40.50.620 234 377 9.9E-42 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 Gene3D G3DSA:3.40.50.620 441 584 9.9E-42 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 PANTHER PTHR11772 2 382 2.1E-57 T 23-04-2016 DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 PANTHER PTHR11772 438 523 2.1E-57 T 23-04-2016 DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 PANTHER PTHR11772:SF10 2 382 2.1E-57 T 23-04-2016 DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 PANTHER PTHR11772:SF10 438 523 2.1E-57 T 23-04-2016 DC74_RS01980 63a4d5bced20c2e5ae5d7715f390037d 595 Gene3D G3DSA:3.60.20.10 1 215 6.2E-42 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS05735 218798ebe2224d5e6217b2d788ff51cf 402 PANTHER PTHR23513:SF6 10 402 3.7E-46 T 23-04-2016 DC74_RS05735 218798ebe2224d5e6217b2d788ff51cf 402 PANTHER PTHR23513 10 402 3.7E-46 T 23-04-2016 DC74_RS05735 218798ebe2224d5e6217b2d788ff51cf 402 Pfam PF07690 Major Facilitator Superfamily 10 311 2.5E-18 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS05735 218798ebe2224d5e6217b2d788ff51cf 402 Gene3D G3DSA:1.20.1250.20 10 181 9.6E-18 T 23-04-2016 DC74_RS05735 218798ebe2224d5e6217b2d788ff51cf 402 Gene3D G3DSA:1.20.1250.20 207 389 8.2E-8 T 23-04-2016 DC74_RS05735 218798ebe2224d5e6217b2d788ff51cf 402 SUPERFAMILY SSF103473 10 391 4.05E-39 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS07240 6de28416c14f8591076595c8d076ae59 246 Gene3D G3DSA:3.40.50.150 41 216 4.2E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS07240 6de28416c14f8591076595c8d076ae59 246 PANTHER PTHR10108 41 203 5.1E-27 T 23-04-2016 DC74_RS07240 6de28416c14f8591076595c8d076ae59 246 SUPERFAMILY SSF53335 30 218 1.82E-39 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS07240 6de28416c14f8591076595c8d076ae59 246 Pfam PF08241 Methyltransferase domain 54 149 3.4E-20 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS31460 aa675cee52c4ab8a37c22b650a52b7bb 143 Pfam PF00545 ribonuclease 58 137 8.2E-29 T 23-04-2016 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 DC74_RS31460 aa675cee52c4ab8a37c22b650a52b7bb 143 SUPERFAMILY SSF53933 49 140 2.83E-37 T 23-04-2016 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 DC74_RS31460 aa675cee52c4ab8a37c22b650a52b7bb 143 Gene3D G3DSA:3.10.450.30 50 139 1.7E-40 T 23-04-2016 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 DC74_RS34550 23bd275dd6b883ace3fedac11de1a631 188 Gene3D G3DSA:1.10.357.10 10 186 1.9E-31 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS34550 23bd275dd6b883ace3fedac11de1a631 188 PANTHER PTHR30328:SF4 12 186 6.8E-32 T 23-04-2016 DC74_RS34550 23bd275dd6b883ace3fedac11de1a631 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 8.4E-16 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34550 23bd275dd6b883ace3fedac11de1a631 188 SUPERFAMILY SSF48498 81 186 5.26E-13 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS34550 23bd275dd6b883ace3fedac11de1a631 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.2E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34550 23bd275dd6b883ace3fedac11de1a631 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.2E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34550 23bd275dd6b883ace3fedac11de1a631 188 PANTHER PTHR30328 12 186 6.8E-32 T 23-04-2016 DC74_RS34550 23bd275dd6b883ace3fedac11de1a631 188 SUPERFAMILY SSF46689 8 77 7.18E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF53901 30 394 1.18E-93 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF47336 4763 4877 1.83E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF53901 6549 6774 4.2E-102 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF53901 6404 6522 4.2E-102 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00823 Phosphopantetheine attachment site 1703 1775 3.7E-29 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00823 Phosphopantetheine attachment site 7804 7876 1.6E-31 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00823 Phosphopantetheine attachment site 4770 4842 9.6E-26 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00823 Phosphopantetheine attachment site 3239 3311 6.2E-28 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00823 Phosphopantetheine attachment site 9329 9401 2.2E-32 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00823 Phosphopantetheine attachment site 6313 6385 6.7E-33 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF55048 5524 5588 1.7E-13 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM01294 6314 6381 8.2E-8 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM01294 3240 3307 2.9E-5 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM01294 7805 7872 4.0E-7 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM01294 9330 9397 1.4E-5 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM01294 1704 1771 6.4E-6 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM01294 4771 4838 7.1E-4 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF51735 6026 6272 6.04E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF47336 3235 3349 1.26E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00550 Phosphopantetheine attachment site 9331 9397 9.4E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00550 Phosphopantetheine attachment site 3241 3307 4.2E-9 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00550 Phosphopantetheine attachment site 1707 1771 6.5E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00550 Phosphopantetheine attachment site 7807 7872 1.4E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00550 Phosphopantetheine attachment site 6315 6381 5.0E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00550 Phosphopantetheine attachment site 4772 4838 2.5E-9 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF51735 2957 3187 2.17E-47 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.366.10 549 681 2.0E-74 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.366.10 5390 5519 6.1E-81 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.366.10 5588 5699 6.1E-81 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.366.10 8417 8543 1.6E-81 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.366.10 8609 8723 1.6E-81 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.366.10 2317 2445 4.8E-73 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.366.10 2514 2625 4.8E-73 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.366.10 750 854 2.0E-74 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF53901 7894 8265 6.9E-97 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF51735 4270 4475 1.06E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF52151 555 687 1.15E-69 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF52151 751 851 1.15E-69 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1955 1971 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 185 201 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5024 5040 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 6566 6582 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 8056 8072 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3493 3509 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF51735 7522 7746 2.55E-20 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF47336 9322 9407 6.67E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF55048 7035 7096 9.94E-9 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF51735 5807 6014 2.24E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2050 2167 2.1E-43 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 280 397 3.1E-42 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5119 5236 3.2E-41 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 8151 8268 4.1E-43 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3588 3705 1.0E-42 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 6662 6776 3.4E-42 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.50.720 7525 7702 5.3E-9 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.47.10 8156 8320 8.1E-60 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.47.10 3593 3758 1.5E-62 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.47.10 6666 6830 3.0E-63 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.47.10 5124 5289 8.7E-62 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.47.10 2055 2218 1.4E-64 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.47.10 285 450 5.2E-61 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF51735 1224 1410 3.15E-31 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00826 942 1104 7.0E-86 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.47.10 1791 2054 3.4E-91 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF55048 8548 8609 4.45E-12 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2959 3138 5.4E-50 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7526 7698 7.5E-8 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1421 1601 1.5E-60 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4489 4668 2.2E-47 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6028 6207 2.7E-60 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9047 9226 4.2E-59 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.366.10 7097 7217 4.1E-80 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.366.10 4052 4174 1.1E-77 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.366.10 3851 3984 1.1E-77 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.366.10 6910 7031 4.1E-80 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF52151 6913 7036 9.16E-74 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF52151 7097 7196 9.16E-74 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF55048 686 750 1.83E-12 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF52151 3860 3989 5.75E-69 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF52151 4053 4149 5.75E-69 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF53901 1790 2165 8.23E-104 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF51735 7313 7514 6.3E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF52151 2515 2615 2.88E-69 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF08990 Erythronolide synthase docking 3 27 3.9E-9 T 23-04-2016 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF53901 4858 5234 8.11E-99 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF52151 8610 8711 1.02E-74 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF47336 7798 7913 1.26E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5397 5697 1.4E-129 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3864 4161 1.1E-122 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2323 2623 1.3E-116 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6917 7203 1.1E-123 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 559 875 3.7E-116 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8426 8719 1.4E-135 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF52151 2319 2451 2.88E-69 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF55048 3988 4052 2.09E-10 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.47.10 36 284 5.5E-87 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.47.10 7900 8155 5.5E-86 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.47.10 6409 6665 3.9E-90 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.47.10 4864 5123 4.9E-90 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.47.10 3336 3592 1.7E-90 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF47336 6307 6422 1.57E-23 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF51735 9045 9294 1.78E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF51735 1419 1633 2.04E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF47336 1698 1809 3.14E-24 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 PANTHER PTHR11712:SF242 6 1771 0.0 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF52151 5393 5525 7.59E-74 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF52151 5589 5683 7.59E-74 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00698 Acyl transferase domain 558 892 1.1E-50 T 23-04-2016 IPR014043 Acyl transferase DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00698 Acyl transferase domain 5396 5716 3.4E-59 T 23-04-2016 IPR014043 Acyl transferase DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00698 Acyl transferase domain 3862 4180 4.6E-91 T 23-04-2016 IPR014043 Acyl transferase DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00698 Acyl transferase domain 8426 8739 1.1E-65 T 23-04-2016 IPR014043 Acyl transferase DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00698 Acyl transferase domain 2323 2641 2.3E-55 T 23-04-2016 IPR014043 Acyl transferase DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00698 Acyl transferase domain 6917 7222 1.1E-56 T 23-04-2016 IPR014043 Acyl transferase DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 PANTHER PTHR11712 6 1771 0.0 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.30.70.250 685 749 3.1E-9 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.30.70.250 7035 7096 9.4E-5 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.30.70.250 2450 2513 1.4E-6 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.30.70.250 8548 8608 1.8E-7 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.30.70.250 3988 4051 1.2E-5 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.30.70.250 5523 5587 1.7E-8 T 23-04-2016 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3334 3580 6.3E-89 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6407 6653 3.7E-85 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1794 2042 8.0E-91 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4862 5111 4.0E-92 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7898 8143 3.4E-81 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 272 5.4E-78 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.50.720 6028 6210 5.6E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.50.720 9047 9228 2.1E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.50.720 2959 3172 5.0E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.50.720 9314 9330 2.1E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.50.720 4489 4670 1.8E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:3.40.50.720 1421 1626 3.9E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF52151 8422 8549 1.02E-74 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF51735 4485 4739 1.44E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF55048 2450 2514 4.58E-11 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF53901 3332 3696 7.66E-105 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF51735 8829 9035 5.12E-49 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF14765 Polyketide synthase dehydratase 942 1216 2.4E-52 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:1.10.1200.10 6312 6385 4.5E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:1.10.1200.10 3238 3312 5.6E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:1.10.1200.10 1699 1775 8.8E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:1.10.1200.10 9331 9401 1.5E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:1.10.1200.10 7801 7876 1.6E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Gene3D G3DSA:1.10.1200.10 4768 4843 9.7E-19 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF08659 KR domain 9047 9224 6.7E-58 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF08659 KR domain 2959 3137 1.2E-59 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF08659 KR domain 6028 6206 3.5E-62 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF08659 KR domain 7526 7696 6.4E-18 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF08659 KR domain 1421 1599 7.2E-58 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF08659 KR domain 4489 4667 4.1E-55 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4797 4812 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1730 1745 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6340 6355 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3266 3281 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 ProSitePatterns PS00012 Phosphopantetheine attachment site. 9356 9371 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7831 7846 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00825 Beta-ketoacyl synthase 1796 2220 2.6E-219 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00825 Beta-ketoacyl synthase 3336 3758 3.2E-213 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00825 Beta-ketoacyl synthase 6409 6829 2.0E-202 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00825 Beta-ketoacyl synthase 4864 5289 2.1E-213 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00825 Beta-ketoacyl synthase 7900 8321 6.9E-201 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SMART SM00825 Beta-ketoacyl synthase 36 450 2.8E-199 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3708 3827 7.4E-14 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 6779 6868 2.1E-12 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 400 519 5.7E-16 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5239 5361 2.0E-19 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2170 2287 3.1E-15 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 8271 8387 1.2E-10 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS06835 fe2b4138d07f2d4a121ffbf9245a3149 9494 SUPERFAMILY SSF51735 2736 2944 1.77E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29945 79c6f7ec850b8e4670def1339cd3e218 512 PIRSF PIRSF002744 2 476 2.5E-116 T 23-04-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 DC74_RS29945 79c6f7ec850b8e4670def1339cd3e218 512 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 26 446 1.0E-53 T 23-04-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 DC74_RS29945 79c6f7ec850b8e4670def1339cd3e218 512 PRINTS PR00173 Glutamate-aspartate symporter signature 63 83 7.4E-6 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS29945 79c6f7ec850b8e4670def1339cd3e218 512 PRINTS PR00173 Glutamate-aspartate symporter signature 332 351 7.4E-6 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS29945 79c6f7ec850b8e4670def1339cd3e218 512 PRINTS PR00173 Glutamate-aspartate symporter signature 136 161 7.4E-6 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS29945 79c6f7ec850b8e4670def1339cd3e218 512 PANTHER PTHR31806 19 478 1.5E-126 T 23-04-2016 DC74_RS05000 1fcf0e473d2c1f5a489f66d8f874acd7 301 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 9 295 49.004 T 23-04-2016 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747|UniPathway: UPA00946 DC74_RS05000 1fcf0e473d2c1f5a489f66d8f874acd7 301 ProSitePatterns PS00161 Isocitrate lyase signature. 124 129 - T 23-04-2016 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 DC74_RS05000 1fcf0e473d2c1f5a489f66d8f874acd7 301 SUPERFAMILY SSF51621 6 294 2.92E-101 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS05000 1fcf0e473d2c1f5a489f66d8f874acd7 301 PANTHER PTHR21631 10 285 5.6E-121 T 23-04-2016 DC74_RS05000 1fcf0e473d2c1f5a489f66d8f874acd7 301 PANTHER PTHR21631:SF4 10 285 5.6E-121 T 23-04-2016 DC74_RS05000 1fcf0e473d2c1f5a489f66d8f874acd7 301 Gene3D G3DSA:3.20.20.60 10 290 1.8E-99 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS05000 1fcf0e473d2c1f5a489f66d8f874acd7 301 Pfam PF13714 Phosphoenolpyruvate phosphomutase 15 256 3.4E-51 T 23-04-2016 DC74_RS05000 1fcf0e473d2c1f5a489f66d8f874acd7 301 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 12 293 1.0E-126 T 23-04-2016 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747|UniPathway: UPA00946 DC74_RS22555 1c679c1fb3cf2d3c8e2878ee4dfd572b 416 Pfam PF10728 Domain of unknown function (DUF2520) 149 274 7.0E-39 T 23-04-2016 IPR018931 Domain of unknown function DUF2520 DC74_RS22555 1c679c1fb3cf2d3c8e2878ee4dfd572b 416 Pfam PF10727 Rossmann-like domain 8 132 2.7E-41 T 23-04-2016 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain DC74_RS22555 1c679c1fb3cf2d3c8e2878ee4dfd572b 416 PANTHER PTHR40459 6 310 5.0E-105 T 23-04-2016 DC74_RS22555 1c679c1fb3cf2d3c8e2878ee4dfd572b 416 Gene3D G3DSA:3.40.50.720 16 178 1.8E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS22555 1c679c1fb3cf2d3c8e2878ee4dfd572b 416 Gene3D G3DSA:1.10.1040.20 182 279 1.2E-31 T 23-04-2016 IPR018931 Domain of unknown function DUF2520 DC74_RS22555 1c679c1fb3cf2d3c8e2878ee4dfd572b 416 SUPERFAMILY SSF48179 182 282 1.8E-24 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS22555 1c679c1fb3cf2d3c8e2878ee4dfd572b 416 SUPERFAMILY SSF51735 18 179 8.55E-29 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS22555 1c679c1fb3cf2d3c8e2878ee4dfd572b 416 PANTHER PTHR40459:SF1 6 310 5.0E-105 T 23-04-2016 DC74_RS22415 2987f5bb8d9fa1878653f3d8c09f9d88 163 PANTHER PTHR10286 3 159 1.4E-68 T 23-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 DC74_RS22415 2987f5bb8d9fa1878653f3d8c09f9d88 163 SUPERFAMILY SSF50324 3 157 2.35E-57 T 23-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 DC74_RS22415 2987f5bb8d9fa1878653f3d8c09f9d88 163 Pfam PF00719 Inorganic pyrophosphatase 5 157 9.3E-52 T 23-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 DC74_RS22415 2987f5bb8d9fa1878653f3d8c09f9d88 163 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 23-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 DC74_RS22415 2987f5bb8d9fa1878653f3d8c09f9d88 163 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 32.862 T 23-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 DC74_RS22415 2987f5bb8d9fa1878653f3d8c09f9d88 163 Gene3D G3DSA:3.90.80.10 2 159 5.6E-54 T 23-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 DC74_RS27640 7131bac54fc1b8350516ee87181b01ab 731 PANTHER PTHR33406:SF5 4 728 4.8E-196 T 23-04-2016 DC74_RS27640 7131bac54fc1b8350516ee87181b01ab 731 SUPERFAMILY SSF82866 111 330 9.68E-29 T 23-04-2016 DC74_RS27640 7131bac54fc1b8350516ee87181b01ab 731 Gene3D G3DSA:1.20.1640.10 479 701 2.6E-25 T 23-04-2016 DC74_RS27640 7131bac54fc1b8350516ee87181b01ab 731 Gene3D G3DSA:1.20.1640.10 138 337 8.4E-27 T 23-04-2016 DC74_RS27640 7131bac54fc1b8350516ee87181b01ab 731 PANTHER PTHR33406 4 728 4.8E-196 T 23-04-2016 DC74_RS27640 7131bac54fc1b8350516ee87181b01ab 731 Pfam PF03176 MMPL family 467 696 3.4E-27 T 23-04-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 DC74_RS27640 7131bac54fc1b8350516ee87181b01ab 731 Pfam PF03176 MMPL family 44 366 3.7E-60 T 23-04-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 DC74_RS27640 7131bac54fc1b8350516ee87181b01ab 731 SUPERFAMILY SSF82866 462 696 5.49E-23 T 23-04-2016 DC74_RS34505 024afd683e8dba6e6c20b914e2a6d2e9 347 Gene3D G3DSA:3.40.50.2300 176 306 2.3E-37 T 23-04-2016 DC74_RS34505 024afd683e8dba6e6c20b914e2a6d2e9 347 Gene3D G3DSA:1.10.260.40 4 55 1.6E-23 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS34505 024afd683e8dba6e6c20b914e2a6d2e9 347 Gene3D G3DSA:3.40.50.2300 56 175 5.1E-37 T 23-04-2016 DC74_RS34505 024afd683e8dba6e6c20b914e2a6d2e9 347 PANTHER PTHR30146 3 336 3.2E-95 T 23-04-2016 DC74_RS34505 024afd683e8dba6e6c20b914e2a6d2e9 347 Pfam PF13377 Periplasmic binding protein-like domain 172 334 5.0E-33 T 23-04-2016 DC74_RS34505 024afd683e8dba6e6c20b914e2a6d2e9 347 SUPERFAMILY SSF53822 61 317 3.03E-60 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS34505 024afd683e8dba6e6c20b914e2a6d2e9 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 3.5E-15 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS34505 024afd683e8dba6e6c20b914e2a6d2e9 347 SMART SM00354 3 73 3.6E-27 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS34505 024afd683e8dba6e6c20b914e2a6d2e9 347 SUPERFAMILY SSF47413 4 61 1.07E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS07100 1726b06b3a7297068f08ab62611c4639 415 SUPERFAMILY SSF53850 36 402 5.58E-52 T 23-04-2016 DC74_RS07100 1726b06b3a7297068f08ab62611c4639 415 Pfam PF01547 Bacterial extracellular solute-binding protein 42 320 5.0E-26 T 23-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 DC74_RS07100 1726b06b3a7297068f08ab62611c4639 415 Gene3D G3DSA:3.40.190.10 155 336 2.0E-24 T 23-04-2016 DC74_RS07100 1726b06b3a7297068f08ab62611c4639 415 Gene3D G3DSA:3.40.190.10 42 154 5.3E-11 T 23-04-2016 DC74_RS07100 1726b06b3a7297068f08ab62611c4639 415 PANTHER PTHR30061:SF1 4 405 1.5E-42 T 23-04-2016 DC74_RS07100 1726b06b3a7297068f08ab62611c4639 415 PANTHER PTHR30061 4 405 1.5E-42 T 23-04-2016 DC74_RS29745 8c160360959f9ce43bd1bd0434a2c04e 424 PANTHER PTHR32196 263 423 1.4E-120 T 23-04-2016 DC74_RS29745 8c160360959f9ce43bd1bd0434a2c04e 424 PANTHER PTHR32196 16 208 1.4E-120 T 23-04-2016 DC74_RS29745 8c160360959f9ce43bd1bd0434a2c04e 424 PANTHER PTHR32196:SF32 263 423 1.4E-120 T 23-04-2016 DC74_RS29745 8c160360959f9ce43bd1bd0434a2c04e 424 PANTHER PTHR32196:SF32 16 208 1.4E-120 T 23-04-2016 DC74_RS29745 8c160360959f9ce43bd1bd0434a2c04e 424 Pfam PF02653 Branched-chain amino acid transport system / permease component 75 408 7.5E-38 T 23-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 Gene3D G3DSA:1.10.630.10 26 417 3.8E-89 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PANTHER PTHR11712 33 417 2.9E-58 T 23-04-2016 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 361 370 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 SUPERFAMILY SSF48264 30 392 4.58E-73 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00359 B-class P450 signature 150 166 4.8E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00359 B-class P450 signature 368 379 4.8E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00359 B-class P450 signature 311 338 4.8E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00359 B-class P450 signature 339 354 4.8E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00359 B-class P450 signature 101 112 4.8E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00359 B-class P450 signature 294 305 4.8E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00359 B-class P450 signature 210 232 4.8E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00359 B-class P450 signature 359 368 4.8E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00359 B-class P450 signature 167 182 4.8E-39 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00385 P450 superfamily signature 368 379 3.4E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00385 P450 superfamily signature 259 276 3.4E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00385 P450 superfamily signature 294 305 3.4E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 PRINTS PR00385 P450 superfamily signature 359 368 3.4E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35125 87ccdc97aa234de9307609cd3da53bb4 419 Pfam PF00067 Cytochrome P450 202 391 5.5E-22 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS15690 f76d41b727103ee9df6a2c92f50d6c13 497 PANTHER PTHR11699:SF27 1 484 5.9E-262 T 23-04-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 DC74_RS15690 f76d41b727103ee9df6a2c92f50d6c13 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS15690 f76d41b727103ee9df6a2c92f50d6c13 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 4 481 3.1E-243 T 23-04-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 DC74_RS15690 f76d41b727103ee9df6a2c92f50d6c13 497 Gene3D G3DSA:3.40.309.10 261 442 7.4E-64 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS15690 f76d41b727103ee9df6a2c92f50d6c13 497 PANTHER PTHR11699 1 484 5.9E-262 T 23-04-2016 DC74_RS15690 f76d41b727103ee9df6a2c92f50d6c13 497 Gene3D G3DSA:3.40.605.10 3 260 1.7E-87 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS15690 f76d41b727103ee9df6a2c92f50d6c13 497 SUPERFAMILY SSF53720 2 483 5.11E-146 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS15690 f76d41b727103ee9df6a2c92f50d6c13 497 Pfam PF00171 Aldehyde dehydrogenase family 21 477 1.2E-136 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS30865 dea5bba4d4258560a7c76d017bf2c37a 197 Pfam PF13508 Acetyltransferase (GNAT) domain 76 167 2.8E-6 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS30865 dea5bba4d4258560a7c76d017bf2c37a 197 SUPERFAMILY SSF55729 50 172 1.89E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS30865 dea5bba4d4258560a7c76d017bf2c37a 197 Gene3D G3DSA:3.40.630.30 57 172 1.5E-15 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS04025 a979e0cb81c66ce622e4d3dd45448bb7 124 Pfam PF13586 Transposase DDE domain 39 113 4.4E-11 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS04025 a979e0cb81c66ce622e4d3dd45448bb7 124 PANTHER PTHR30007 1 118 1.8E-22 T 23-04-2016 DC74_RS04025 a979e0cb81c66ce622e4d3dd45448bb7 124 PANTHER PTHR30007:SF0 1 118 1.8E-22 T 23-04-2016 DC74_RS00765 72946bbfb677565a4d0d4ed918d0be06 267 Gene3D G3DSA:3.40.50.150 16 178 3.0E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS00765 72946bbfb677565a4d0d4ed918d0be06 267 Gene3D G3DSA:3.40.50.150 217 244 3.0E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS00765 72946bbfb677565a4d0d4ed918d0be06 267 PANTHER PTHR10108 223 258 7.9E-12 T 23-04-2016 DC74_RS00765 72946bbfb677565a4d0d4ed918d0be06 267 PANTHER PTHR10108 14 201 7.9E-12 T 23-04-2016 DC74_RS00765 72946bbfb677565a4d0d4ed918d0be06 267 PANTHER PTHR10108:SF705 223 258 7.9E-12 T 23-04-2016 DC74_RS00765 72946bbfb677565a4d0d4ed918d0be06 267 PANTHER PTHR10108:SF705 14 201 7.9E-12 T 23-04-2016 DC74_RS00765 72946bbfb677565a4d0d4ed918d0be06 267 Pfam PF13649 Methyltransferase domain 60 147 1.0E-11 T 23-04-2016 DC74_RS00765 72946bbfb677565a4d0d4ed918d0be06 267 SUPERFAMILY SSF53335 16 261 3.32E-32 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS18710 f0a18115fdb44faafa5777330a921747 115 Gene3D G3DSA:3.90.470.10 1 112 3.9E-42 T 23-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 DC74_RS18710 f0a18115fdb44faafa5777330a921747 115 ProSitePatterns PS00464 Ribosomal protein L22 signature. 84 108 - T 23-04-2016 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18710 f0a18115fdb44faafa5777330a921747 115 SUPERFAMILY SSF54843 1 112 5.76E-42 T 23-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 DC74_RS18710 f0a18115fdb44faafa5777330a921747 115 PANTHER PTHR13501 1 109 9.0E-47 T 23-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 DC74_RS18710 f0a18115fdb44faafa5777330a921747 115 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 108 5.1E-45 T 23-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 DC74_RS18710 f0a18115fdb44faafa5777330a921747 115 Pfam PF00237 Ribosomal protein L22p/L17e 8 108 1.2E-32 T 23-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 DC74_RS18710 f0a18115fdb44faafa5777330a921747 115 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 111 29.876 T 23-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 DC74_RS24580 d8195eed4067167dbc27d55e461d36a9 329 PIRSF PIRSF000102 2 327 3.2E-61 T 23-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 DC74_RS24580 d8195eed4067167dbc27d55e461d36a9 329 Gene3D G3DSA:3.40.50.720 5 154 5.9E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS24580 d8195eed4067167dbc27d55e461d36a9 329 Gene3D G3DSA:3.90.110.10 156 326 1.8E-76 T 23-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 DC74_RS24580 d8195eed4067167dbc27d55e461d36a9 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 323 1.4E-34 T 23-04-2016 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 DC74_RS24580 d8195eed4067167dbc27d55e461d36a9 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 57.495 T 23-04-2016 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 DC74_RS24580 d8195eed4067167dbc27d55e461d36a9 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 23-04-2016 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: REACT_474 DC74_RS24580 d8195eed4067167dbc27d55e461d36a9 329 PANTHER PTHR23382 5 328 3.5E-195 T 23-04-2016 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 DC74_RS24580 d8195eed4067167dbc27d55e461d36a9 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 323 1.4E-147 T 23-04-2016 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 DC74_RS24580 d8195eed4067167dbc27d55e461d36a9 329 SUPERFAMILY SSF56327 157 324 8.65E-62 T 23-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 DC74_RS24580 d8195eed4067167dbc27d55e461d36a9 329 SUPERFAMILY SSF51735 4 156 1.22E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS24580 d8195eed4067167dbc27d55e461d36a9 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 148 7.3E-32 T 23-04-2016 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 DC74_RS05520 9760bfb851a9430051b1eca010ad770e 410 Gene3D G3DSA:3.40.50.2000 245 327 6.6E-4 T 23-04-2016 DC74_RS05520 9760bfb851a9430051b1eca010ad770e 410 Pfam PF04230 Polysaccharide pyruvyl transferase 21 328 1.7E-21 T 23-04-2016 IPR007345 Polysaccharide pyruvyl transferase DC74_RS05520 9760bfb851a9430051b1eca010ad770e 410 PANTHER PTHR36836 7 404 3.2E-237 T 23-04-2016 DC74_RS05520 9760bfb851a9430051b1eca010ad770e 410 PANTHER PTHR36836:SF2 7 404 3.2E-237 T 23-04-2016 DC74_RS34960 3500f54533318bcb1f9f77fed0bf1e20 442 SUPERFAMILY SSF55874 307 420 1.58E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS34960 3500f54533318bcb1f9f77fed0bf1e20 442 PANTHER PTHR24421:SF26 50 436 2.9E-108 T 23-04-2016 DC74_RS34960 3500f54533318bcb1f9f77fed0bf1e20 442 Pfam PF07730 Histidine kinase 219 285 1.0E-19 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS34960 3500f54533318bcb1f9f77fed0bf1e20 442 PANTHER PTHR24421 50 436 2.9E-108 T 23-04-2016 DC74_RS34960 3500f54533318bcb1f9f77fed0bf1e20 442 Gene3D G3DSA:3.30.565.10 308 425 8.5E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 855 0.0 T 23-04-2016 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 SUPERFAMILY SSF63737 5 200 1.44E-38 T 23-04-2016 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 Pfam PF11838 ERAP1-like C-terminal domain 540 849 1.2E-60 T 23-04-2016 IPR024571 ERAP1-like C-terminal domain DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 SUPERFAMILY SSF55486 212 462 2.34E-73 T 23-04-2016 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 PANTHER PTHR11533 8 649 4.7E-179 T 23-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 PANTHER PTHR11533 672 723 4.7E-179 T 23-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 Pfam PF01433 Peptidase family M1 95 395 4.8E-73 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 267 277 1.0E-22 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 137 152 1.0E-22 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 183 198 1.0E-22 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 301 316 1.0E-22 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 320 332 1.0E-22 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 PANTHER PTHR11533:SF190 8 649 4.7E-179 T 23-04-2016 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 Gene3D G3DSA:1.10.390.10 314 463 1.6E-41 T 23-04-2016 DC74_RS15430 869c104c5b34d7636d60204ad0b8f197 862 PANTHER PTHR11533:SF190 672 723 4.7E-179 T 23-04-2016 DC74_RS26880 582437041a721859aec39542d2149aa0 359 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 23-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 DC74_RS26880 582437041a721859aec39542d2149aa0 359 Gene3D G3DSA:3.30.160.20 213 291 7.5E-35 T 23-04-2016 IPR014720 Double-stranded RNA-binding domain DC74_RS26880 582437041a721859aec39542d2149aa0 359 SMART SM00937 63 181 2.2E-52 T 23-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 DC74_RS26880 582437041a721859aec39542d2149aa0 359 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 357 2.7E-150 T 23-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 DC74_RS26880 582437041a721859aec39542d2149aa0 359 PANTHER PTHR11075 1 358 1.3E-154 T 23-04-2016 DC74_RS26880 582437041a721859aec39542d2149aa0 359 Gene3D G3DSA:1.20.58.410 5 87 4.0E-14 T 23-04-2016 DC74_RS26880 582437041a721859aec39542d2149aa0 359 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 359 37.793 T 23-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 DC74_RS26880 582437041a721859aec39542d2149aa0 359 Pfam PF00472 RF-1 domain 214 323 3.9E-41 T 23-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 DC74_RS26880 582437041a721859aec39542d2149aa0 359 PANTHER PTHR11075:SF9 1 358 1.3E-154 T 23-04-2016 DC74_RS26880 582437041a721859aec39542d2149aa0 359 Pfam PF03462 PCRF domain 11 206 6.0E-66 T 23-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 DC74_RS26880 582437041a721859aec39542d2149aa0 359 SUPERFAMILY SSF75620 8 355 5.36E-126 T 23-04-2016 DC74_RS18605 bbdd3f8fdd7551be950823bd50cd288f 208 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 208 1.0E-68 T 23-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 DC74_RS18605 bbdd3f8fdd7551be950823bd50cd288f 208 Gene3D G3DSA:3.10.290.10 101 200 4.0E-30 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS18605 bbdd3f8fdd7551be950823bd50cd288f 208 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 7.6E-25 T 23-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 DC74_RS18605 bbdd3f8fdd7551be950823bd50cd288f 208 ProSitePatterns PS00632 Ribosomal protein S4 signature. 96 120 - T 23-04-2016 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 DC74_RS18605 bbdd3f8fdd7551be950823bd50cd288f 208 SMART SM01390 3 97 1.7E-45 T 23-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 DC74_RS18605 bbdd3f8fdd7551be950823bd50cd288f 208 PANTHER PTHR11831 1 208 2.5E-77 T 23-04-2016 IPR022801 Ribosomal protein S4/S9 DC74_RS18605 bbdd3f8fdd7551be950823bd50cd288f 208 PANTHER PTHR11831:SF4 1 208 2.5E-77 T 23-04-2016 DC74_RS18605 bbdd3f8fdd7551be950823bd50cd288f 208 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 208 32.875 T 23-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 DC74_RS18605 bbdd3f8fdd7551be950823bd50cd288f 208 SUPERFAMILY SSF55174 3 208 1.16E-63 T 23-04-2016 DC74_RS18605 bbdd3f8fdd7551be950823bd50cd288f 208 Pfam PF01479 S4 domain 99 145 1.8E-18 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS18605 bbdd3f8fdd7551be950823bd50cd288f 208 SMART SM00363 98 160 4.5E-17 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS18605 bbdd3f8fdd7551be950823bd50cd288f 208 Gene3D G3DSA:1.10.1050.10 1 100 1.9E-41 T 23-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 DC74_RS21880 5cbd92a568221628475d88bd680f2296 578 PANTHER PTHR24221 4 575 1.1E-179 T 23-04-2016 DC74_RS21880 5cbd92a568221628475d88bd680f2296 578 Gene3D G3DSA:3.40.50.300 338 570 8.8E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21880 5cbd92a568221628475d88bd680f2296 578 SMART SM00382 365 553 8.7E-19 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS21880 5cbd92a568221628475d88bd680f2296 578 SUPERFAMILY SSF90123 5 324 1.12E-72 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS21880 5cbd92a568221628475d88bd680f2296 578 Pfam PF00005 ABC transporter 357 506 2.4E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS21880 5cbd92a568221628475d88bd680f2296 578 Pfam PF00664 ABC transporter transmembrane region 18 286 2.3E-45 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS21880 5cbd92a568221628475d88bd680f2296 578 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS21880 5cbd92a568221628475d88bd680f2296 578 Gene3D G3DSA:1.20.1560.10 4 322 2.7E-75 T 23-04-2016 DC74_RS21880 5cbd92a568221628475d88bd680f2296 578 SUPERFAMILY SSF52540 330 575 7.85E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30290 6947350c4987df5396450f80827146ec 281 Pfam PF01609 Transposase DDE domain 112 266 2.4E-15 T 23-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 DC74_RS30290 6947350c4987df5396450f80827146ec 281 PANTHER PTHR30007 10 278 7.7E-101 T 23-04-2016 DC74_RS30290 6947350c4987df5396450f80827146ec 281 PANTHER PTHR30007:SF0 10 278 7.7E-101 T 23-04-2016 DC74_RS30290 6947350c4987df5396450f80827146ec 281 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 14 93 7.3E-25 T 23-04-2016 IPR025161 Putative transposase IS4/IS5 family DC74_RS08420 7d56f5be58aaafa3412082c373d6b1df 523 Gene3D G3DSA:3.30.300.30 413 519 3.7E-29 T 23-04-2016 DC74_RS08420 7d56f5be58aaafa3412082c373d6b1df 523 Pfam PF13193 AMP-binding enzyme C-terminal domain 428 510 1.3E-22 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS08420 7d56f5be58aaafa3412082c373d6b1df 523 Gene3D G3DSA:2.30.38.10 337 411 3.3E-26 T 23-04-2016 DC74_RS08420 7d56f5be58aaafa3412082c373d6b1df 523 Gene3D G3DSA:3.40.50.980 14 185 3.2E-37 T 23-04-2016 DC74_RS08420 7d56f5be58aaafa3412082c373d6b1df 523 PANTHER PTHR24096:SF229 11 520 3.7E-240 T 23-04-2016 DC74_RS08420 7d56f5be58aaafa3412082c373d6b1df 523 Gene3D G3DSA:3.40.50.980 186 328 2.3E-35 T 23-04-2016 DC74_RS08420 7d56f5be58aaafa3412082c373d6b1df 523 Pfam PF00501 AMP-binding enzyme 20 418 1.7E-98 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS08420 7d56f5be58aaafa3412082c373d6b1df 523 SUPERFAMILY SSF56801 9 521 2.49E-146 T 23-04-2016 DC74_RS08420 7d56f5be58aaafa3412082c373d6b1df 523 PANTHER PTHR24096 11 520 3.7E-240 T 23-04-2016 DC74_RS21940 9d38ac05103fc374a9f24153fb6bf113 220 Pfam PF16702 Domain of unknown function (DUF5063) 14 173 3.3E-44 T 23-04-2016 IPR032025 Protein of unknown function DUF5063 DC74_RS20130 61c5e395c77f7f762c42fc7fe68164e4 101 Pfam PF08962 Domain of unknown function (DUF1876) 16 96 2.0E-30 T 23-04-2016 IPR015057 Protein of unknown function DUF1876 DC74_RS20130 61c5e395c77f7f762c42fc7fe68164e4 101 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 15 95 3.0E-16 T 23-04-2016 IPR015057 Protein of unknown function DUF1876 DC74_RS20130 61c5e395c77f7f762c42fc7fe68164e4 101 SUPERFAMILY SSF143212 14 94 1.44E-24 T 23-04-2016 DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 Gene3D G3DSA:3.30.460.10 238 365 2.9E-21 T 23-04-2016 DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 SUPERFAMILY SSF109604 50 234 9.42E-61 T 23-04-2016 DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 Gene3D G3DSA:3.10.20.30 449 501 3.9E-9 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 Pfam PF04607 Region found in RelA / SpoT proteins 302 372 3.6E-13 T 23-04-2016 IPR007685 RelA/SpoT GO:0015969 DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 SUPERFAMILY SSF81271 446 497 1.55E-9 T 23-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 SMART SM00471 86 196 3.5E-11 T 23-04-2016 IPR003607 HD/PDEase domain DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 Pfam PF02824 TGS domain 446 498 2.0E-10 T 23-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 SUPERFAMILY SSF55021 641 716 2.47E-6 T 23-04-2016 DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 Gene3D G3DSA:3.30.70.260 651 712 1.1E-4 T 23-04-2016 DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 PANTHER PTHR21262:SF0 16 717 1.6E-206 T 23-04-2016 DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 SUPERFAMILY SSF81301 237 377 2.13E-29 T 23-04-2016 DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 PANTHER PTHR21262 16 717 1.6E-206 T 23-04-2016 DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 Pfam PF13328 HD domain 71 218 7.6E-39 T 23-04-2016 IPR003607 HD/PDEase domain DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 Pfam PF13291 ACT domain 642 714 2.5E-9 T 23-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 DC74_RS28880 9fca797f2a7f4f690b5656b8e97582f8 721 SMART SM00954 277 385 6.8E-22 T 23-04-2016 IPR007685 RelA/SpoT GO:0015969 DC74_RS12780 efb2cec1766cf340bc792e8b9a00256f 163 PANTHER PTHR39683 1 152 2.2E-73 T 23-04-2016 DC74_RS12780 efb2cec1766cf340bc792e8b9a00256f 163 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 139 1.0E-12 T 23-04-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain DC74_RS12780 efb2cec1766cf340bc792e8b9a00256f 163 Gene3D G3DSA:3.30.530.20 4 144 9.8E-16 T 23-04-2016 IPR023393 START-like domain DC74_RS12780 efb2cec1766cf340bc792e8b9a00256f 163 SUPERFAMILY SSF55961 1 147 4.25E-29 T 23-04-2016 DC74_RS12780 efb2cec1766cf340bc792e8b9a00256f 163 PANTHER PTHR39683:SF1 1 152 2.2E-73 T 23-04-2016 DC74_RS05345 578f767261fcbc053bc719895da51452 408 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 294 382 2.4E-10 T 23-04-2016 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain DC74_RS05345 578f767261fcbc053bc719895da51452 408 SUPERFAMILY SSF47203 266 399 4.03E-18 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS05345 578f767261fcbc053bc719895da51452 408 PIRSF PIRSF016578 10 405 8.6E-25 T 23-04-2016 DC74_RS05345 578f767261fcbc053bc719895da51452 408 Gene3D G3DSA:1.20.140.10 245 400 8.5E-27 T 23-04-2016 DC74_RS05345 578f767261fcbc053bc719895da51452 408 PANTHER PTHR10909 17 403 1.6E-33 T 23-04-2016 DC74_RS05345 578f767261fcbc053bc719895da51452 408 SUPERFAMILY SSF56645 15 254 1.83E-39 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS05345 578f767261fcbc053bc719895da51452 408 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 130 5.1E-14 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS05345 578f767261fcbc053bc719895da51452 408 Gene3D G3DSA:1.10.540.10 14 127 4.4E-20 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS05345 578f767261fcbc053bc719895da51452 408 Gene3D G3DSA:2.40.110.10 154 244 1.0E-18 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 SUPERFAMILY SSF55424 367 485 3.78E-27 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 186 204 3.1E-19 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 3.1E-19 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 288 3.1E-19 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 3.1E-19 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 SUPERFAMILY SSF51905 16 347 8.84E-41 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 367 388 8.2E-51 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 20 42 8.2E-51 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 186 211 8.2E-51 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 8.2E-51 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 52 67 8.2E-51 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 287 8.2E-51 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 455 475 8.2E-51 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 433 448 8.2E-51 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 159 8.2E-51 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 371 476 2.6E-21 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PANTHER PTHR22912 2 484 3.5E-221 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PANTHER PTHR22912:SF166 2 484 3.5E-221 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 Gene3D G3DSA:3.50.50.60 157 345 3.5E-35 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 330 1.8E-44 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 Gene3D G3DSA:3.50.50.60 18 156 3.7E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 PIRSF PIRSF000350 9 485 1.8E-64 T 23-04-2016 DC74_RS16445 b5105c8d42fc1817319ab9c93baa4264 487 Gene3D G3DSA:3.30.390.30 366 484 7.0E-27 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS03425 d380bab3fbdfd9d52afddbb6793f4c70 308 SMART SM00829 10 305 8.8E-11 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS03425 d380bab3fbdfd9d52afddbb6793f4c70 308 SUPERFAMILY SSF50129 3 120 2.13E-27 T 23-04-2016 IPR011032 GroES-like DC74_RS03425 d380bab3fbdfd9d52afddbb6793f4c70 308 SUPERFAMILY SSF50129 277 305 2.13E-27 T 23-04-2016 IPR011032 GroES-like DC74_RS03425 d380bab3fbdfd9d52afddbb6793f4c70 308 SUPERFAMILY SSF51735 116 239 1.81E-19 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03425 d380bab3fbdfd9d52afddbb6793f4c70 308 Pfam PF13602 Zinc-binding dehydrogenase 200 305 3.2E-12 T 23-04-2016 DC74_RS03425 d380bab3fbdfd9d52afddbb6793f4c70 308 PANTHER PTHR11695:SF605 15 308 3.1E-51 T 23-04-2016 DC74_RS03425 d380bab3fbdfd9d52afddbb6793f4c70 308 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 5.0E-8 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS03425 d380bab3fbdfd9d52afddbb6793f4c70 308 PANTHER PTHR11695 15 308 3.1E-51 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS03425 d380bab3fbdfd9d52afddbb6793f4c70 308 Gene3D G3DSA:3.40.50.720 145 239 7.6E-18 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03425 d380bab3fbdfd9d52afddbb6793f4c70 308 Gene3D G3DSA:3.90.180.10 3 144 1.6E-27 T 23-04-2016 IPR011032 GroES-like DC74_RS03425 d380bab3fbdfd9d52afddbb6793f4c70 308 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 143 164 - T 23-04-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 SUPERFAMILY SSF101904 523 843 2.75E-99 T 23-04-2016 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 687 735 1.3E-11 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 528 573 3.4E-14 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 740 786 3.0E-12 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 635 683 1.5E-7 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 790 834 3.3E-11 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 579 614 8.6E-9 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 PANTHER PTHR10169 27 810 0.0 T 23-04-2016 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 21 838 27.418 T 23-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 PANTHER PTHR10169:SF48 27 810 0.0 T 23-04-2016 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 Gene3D G3DSA:2.120.10.90 521 835 1.8E-118 T 23-04-2016 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 SUPERFAMILY SSF56719 51 511 6.41E-170 T 23-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 29 836 0.0 T 23-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 Gene3D G3DSA:3.90.199.10 51 260 7.8E-114 T 23-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 Gene3D G3DSA:3.90.199.10 358 422 7.8E-114 T 23-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 53 496 2.8E-150 T 23-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 SMART SM00434 32 489 7.0E-277 T 23-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 DC74_RS20660 7734082a43825b1447e181d4229b6531 874 Gene3D G3DSA:3.30.1360.40 261 357 2.5E-33 T 23-04-2016 IPR024946 Arginine repressor C-terminal-like domain DC74_RS34825 5f64b90136de4a30eaf00ba0c7d0af34 251 SUPERFAMILY SSF53448 15 226 1.18E-43 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS34825 5f64b90136de4a30eaf00ba0c7d0af34 251 Pfam PF00535 Glycosyl transferase family 2 16 178 1.2E-27 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS34825 5f64b90136de4a30eaf00ba0c7d0af34 251 Gene3D G3DSA:3.90.550.10 16 221 1.2E-23 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS34825 5f64b90136de4a30eaf00ba0c7d0af34 251 PANTHER PTHR10859 16 239 3.7E-67 T 23-04-2016 DC74_RS40540 f9b8cb359b467d69094eb619c9f45bd1 182 Pfam PF14435 SUKH-4 immunity protein 5 175 6.4E-19 T 23-04-2016 IPR025851 SUKH-4 immunity protein DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 352 542 7.0E-49 T 23-04-2016 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 Gene3D G3DSA:3.40.50.300 179 342 3.5E-28 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 190 212 7.0E-35 T 23-04-2016 DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 290 310 7.0E-35 T 23-04-2016 DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 474 499 7.0E-35 T 23-04-2016 DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 355 377 7.0E-35 T 23-04-2016 DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 455 473 7.0E-35 T 23-04-2016 DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 SUPERFAMILY SSF52540 289 359 5.6E-29 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 SUPERFAMILY SSF52540 392 510 5.6E-29 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 SMART SM00490 422 499 3.4E-12 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 SMART SM00487 177 352 6.2E-21 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 Pfam PF13625 Helicase conserved C-terminal domain 5 133 2.3E-46 T 23-04-2016 IPR032830 Helicase XPB/Ssl2, N-terminal domain DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 PANTHER PTHR11274 4 539 8.3E-192 T 23-04-2016 DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 SUPERFAMILY SSF52540 144 342 1.83E-32 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 Gene3D G3DSA:3.40.50.300 379 533 1.3E-15 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23645 4b1cf8d5afebd1828f23b3a163bf10ed 560 Pfam PF04851 Type III restriction enzyme, res subunit 180 325 1.7E-12 T 23-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 DC74_RS33870 5c536e308bb16da162a80f0b5d4fc582 471 Pfam PF00027 Cyclic nucleotide-binding domain 119 205 3.5E-10 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS33870 5c536e308bb16da162a80f0b5d4fc582 471 SUPERFAMILY SSF51206 90 212 2.36E-17 T 23-04-2016 IPR018490 Cyclic nucleotide-binding-like DC74_RS33870 5c536e308bb16da162a80f0b5d4fc582 471 PANTHER PTHR24567:SF37 22 220 4.5E-179 T 23-04-2016 DC74_RS33870 5c536e308bb16da162a80f0b5d4fc582 471 PANTHER PTHR24567:SF37 288 470 4.5E-179 T 23-04-2016 DC74_RS33870 5c536e308bb16da162a80f0b5d4fc582 471 SMART SM00100 99 222 4.9E-5 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS33870 5c536e308bb16da162a80f0b5d4fc582 471 PANTHER PTHR24567 22 220 4.5E-179 T 23-04-2016 DC74_RS33870 5c536e308bb16da162a80f0b5d4fc582 471 PANTHER PTHR24567 288 470 4.5E-179 T 23-04-2016 DC74_RS33870 5c536e308bb16da162a80f0b5d4fc582 471 Gene3D G3DSA:2.60.120.10 94 217 3.6E-18 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 PANTHER PTHR30620 531 815 2.2E-235 T 23-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 SUPERFAMILY SSF56988 437 596 2.62E-8 T 23-04-2016 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 Gene3D G3DSA:3.40.50.1700 300 390 1.1E-71 T 23-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 Gene3D G3DSA:3.40.50.1700 551 705 1.1E-71 T 23-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 PANTHER PTHR30620:SF18 531 815 2.2E-235 T 23-04-2016 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 312 703 1.4E-57 T 23-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 SUPERFAMILY SSF52279 551 706 4.45E-52 T 23-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 SUPERFAMILY SSF52279 311 390 4.45E-52 T 23-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 PANTHER PTHR30620 1 385 2.2E-235 T 23-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 PRINTS PR00133 Glycosyl hydrolase family 3 signature 59 78 5.0E-30 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 PRINTS PR00133 Glycosyl hydrolase family 3 signature 105 121 5.0E-30 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 PRINTS PR00133 Glycosyl hydrolase family 3 signature 206 224 5.0E-30 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 PRINTS PR00133 Glycosyl hydrolase family 3 signature 30 46 5.0E-30 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 PRINTS PR00133 Glycosyl hydrolase family 3 signature 136 152 5.0E-30 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 Pfam PF07691 PA14 domain 429 499 4.9E-6 T 23-04-2016 IPR011658 PA14 domain DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 SMART SM01217 732 805 5.3E-17 T 23-04-2016 IPR026891 Fibronectin type III-like domain DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 Gene3D G3DSA:3.20.20.300 17 286 1.3E-90 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 SUPERFAMILY SSF51445 2 310 2.32E-86 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 PANTHER PTHR30620:SF18 1 385 2.2E-235 T 23-04-2016 DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 Pfam PF14310 Fibronectin type III-like domain 732 805 2.4E-13 T 23-04-2016 IPR026891 Fibronectin type III-like domain DC74_RS14070 6caf106cd3b6cbae193d35a6fb2020e2 817 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 32 272 2.0E-50 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 SUPERFAMILY SSF52540 19 253 2.3E-17 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 PRINTS PR00364 Disease resistance protein signature 39 54 3.6E-7 T 23-04-2016 DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 PRINTS PR00364 Disease resistance protein signature 111 125 3.6E-7 T 23-04-2016 DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 PRINTS PR00364 Disease resistance protein signature 220 234 3.6E-7 T 23-04-2016 DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 SMART SM00421 715 772 6.3E-22 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 Gene3D G3DSA:1.10.10.10 715 775 6.6E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 SUPERFAMILY SSF48452 500 633 7.05E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 Gene3D G3DSA:1.25.40.10 478 624 2.3E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 Pfam PF00196 Bacterial regulatory proteins, luxR family 718 771 9.0E-17 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 732 748 3.5E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 748 760 3.5E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 718 732 3.5E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 Gene3D G3DSA:3.40.50.300 239 250 2.8E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 Gene3D G3DSA:3.40.50.300 16 153 2.8E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS01005 f2e9df73c40bd42e79b4821b3a424ac6 782 SUPERFAMILY SSF46894 709 774 6.8E-18 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS31905 3616359492d735cc810da3b78b45080f 678 Pfam PF17128 Domain of unknown function (DUF5107) 60 338 2.7E-36 T 23-04-2016 IPR033396 Domain of unknown function DUF5107 DC74_RS31905 3616359492d735cc810da3b78b45080f 678 Gene3D G3DSA:1.25.40.10 587 644 3.1E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS31905 3616359492d735cc810da3b78b45080f 678 Gene3D G3DSA:1.25.40.10 476 542 3.1E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS30910 62e01530eee80ed6a3e1ae29fb34e8ab 275 Pfam PF00561 alpha/beta hydrolase fold 20 247 1.3E-18 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS30910 62e01530eee80ed6a3e1ae29fb34e8ab 275 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 9 259 4.0E-79 T 23-04-2016 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185|UniPathway: UPA00157 DC74_RS30910 62e01530eee80ed6a3e1ae29fb34e8ab 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 4.8E-11 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS30910 62e01530eee80ed6a3e1ae29fb34e8ab 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 4.8E-11 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS30910 62e01530eee80ed6a3e1ae29fb34e8ab 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 4.8E-11 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS30910 62e01530eee80ed6a3e1ae29fb34e8ab 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 205 219 4.8E-11 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS30910 62e01530eee80ed6a3e1ae29fb34e8ab 275 PANTHER PTHR10992:SF818 9 261 3.2E-48 T 23-04-2016 DC74_RS30910 62e01530eee80ed6a3e1ae29fb34e8ab 275 SUPERFAMILY SSF53474 9 260 8.98E-56 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS30910 62e01530eee80ed6a3e1ae29fb34e8ab 275 Gene3D G3DSA:3.40.50.1820 10 260 7.8E-57 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS30910 62e01530eee80ed6a3e1ae29fb34e8ab 275 PANTHER PTHR10992 9 261 3.2E-48 T 23-04-2016 DC74_RS25260 4140dc639ed217b52f3dd921e27f4c4e 290 Gene3D G3DSA:3.40.50.10320 3 288 1.4E-87 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS25260 4140dc639ed217b52f3dd921e27f4c4e 290 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 154 3.8E-26 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS25260 4140dc639ed217b52f3dd921e27f4c4e 290 PANTHER PTHR12993:SF12 1 269 2.7E-153 T 23-04-2016 DC74_RS25260 4140dc639ed217b52f3dd921e27f4c4e 290 SUPERFAMILY SSF102588 4 288 3.27E-75 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS25260 4140dc639ed217b52f3dd921e27f4c4e 290 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 287 1.5E-152 T 23-04-2016 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 DC74_RS25260 4140dc639ed217b52f3dd921e27f4c4e 290 PANTHER PTHR12993 1 269 2.7E-153 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS25260 4140dc639ed217b52f3dd921e27f4c4e 290 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 5 288 65.397 T 23-04-2016 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 DC74_RS06160 99b69f21817fc948899cf0c6fd725050 306 Gene3D G3DSA:3.40.190.10 167 263 5.2E-27 T 23-04-2016 DC74_RS06160 99b69f21817fc948899cf0c6fd725050 306 Pfam PF03466 LysR substrate binding domain 90 291 3.4E-17 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS06160 99b69f21817fc948899cf0c6fd725050 306 SUPERFAMILY SSF46785 1 79 4.08E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06160 99b69f21817fc948899cf0c6fd725050 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 9.3E-17 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS06160 99b69f21817fc948899cf0c6fd725050 306 Gene3D G3DSA:1.10.10.10 1 80 4.6E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06160 99b69f21817fc948899cf0c6fd725050 306 PANTHER PTHR30118 1 301 3.5E-101 T 23-04-2016 DC74_RS06160 99b69f21817fc948899cf0c6fd725050 306 PANTHER PTHR30118:SF5 1 301 3.5E-101 T 23-04-2016 DC74_RS06160 99b69f21817fc948899cf0c6fd725050 306 Gene3D G3DSA:3.40.190.10 267 292 4.9E-18 T 23-04-2016 DC74_RS06160 99b69f21817fc948899cf0c6fd725050 306 Gene3D G3DSA:3.40.190.10 85 166 4.9E-18 T 23-04-2016 DC74_RS06160 99b69f21817fc948899cf0c6fd725050 306 SUPERFAMILY SSF53850 85 289 2.35E-32 T 23-04-2016 DC74_RS19905 761711658326ff47c6f57bea7f97b024 172 Pfam PF10936 Protein of unknown function DUF2617 3 164 1.3E-62 T 23-04-2016 IPR024486 Protein of unknown function DUF2617 DC74_RS19905 761711658326ff47c6f57bea7f97b024 172 ProDom PD339375 PRECURSOR SIGNAL SCO3656 SCO2458 CGL2705 MB2629 RV2598/MT2673.1 4 167 1.0E-67 T 23-04-2016 IPR024486 Protein of unknown function DUF2617 DC74_RS10800 3693a2bd716a87c37fda4b4d69af1aa4 352 PANTHER PTHR11695:SF590 16 352 1.4E-75 T 23-04-2016 DC74_RS10800 3693a2bd716a87c37fda4b4d69af1aa4 352 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 91 5.7E-11 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS10800 3693a2bd716a87c37fda4b4d69af1aa4 352 Gene3D G3DSA:3.90.180.10 1 93 2.3E-17 T 23-04-2016 IPR011032 GroES-like DC74_RS10800 3693a2bd716a87c37fda4b4d69af1aa4 352 SMART SM00829 11 341 1.8E-6 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS10800 3693a2bd716a87c37fda4b4d69af1aa4 352 Pfam PF00107 Zinc-binding dehydrogenase 162 284 2.2E-15 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS10800 3693a2bd716a87c37fda4b4d69af1aa4 352 SUPERFAMILY SSF50129 1 153 2.43E-32 T 23-04-2016 IPR011032 GroES-like DC74_RS10800 3693a2bd716a87c37fda4b4d69af1aa4 352 PANTHER PTHR11695 16 352 1.4E-75 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS10800 3693a2bd716a87c37fda4b4d69af1aa4 352 Gene3D G3DSA:3.40.50.720 132 307 1.5E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10800 3693a2bd716a87c37fda4b4d69af1aa4 352 SUPERFAMILY SSF51735 124 307 4.54E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS21955 09100dfabe096e3129d48d36faa9adb7 166 SUPERFAMILY SSF88659 89 163 6.92E-15 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21955 09100dfabe096e3129d48d36faa9adb7 166 Gene3D G3DSA:1.10.1740.10 9 78 8.6E-15 T 23-04-2016 DC74_RS21955 09100dfabe096e3129d48d36faa9adb7 166 PANTHER PTHR30173 14 166 2.0E-26 T 23-04-2016 DC74_RS21955 09100dfabe096e3129d48d36faa9adb7 166 Pfam PF04542 Sigma-70 region 2 14 78 5.2E-11 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21955 09100dfabe096e3129d48d36faa9adb7 166 Gene3D G3DSA:1.10.10.10 104 163 9.3E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21955 09100dfabe096e3129d48d36faa9adb7 166 Pfam PF08281 Sigma-70, region 4 105 158 1.4E-12 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21955 09100dfabe096e3129d48d36faa9adb7 166 SUPERFAMILY SSF88946 9 79 8.24E-15 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21955 09100dfabe096e3129d48d36faa9adb7 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 161 4.3E-22 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21955 09100dfabe096e3129d48d36faa9adb7 166 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 5 164 1.2E-56 T 23-04-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 PANTHER PTHR10795:SF389 10 399 3.5E-124 T 23-04-2016 DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 160 171 - T 23-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 PRINTS PR00723 Subtilisin serine protease family (S8) signature 155 174 2.5E-19 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 PRINTS PR00723 Subtilisin serine protease family (S8) signature 346 362 2.5E-19 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 PRINTS PR00723 Subtilisin serine protease family (S8) signature 193 206 2.5E-19 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 Gene3D G3DSA:3.40.50.200 131 398 2.5E-83 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 SUPERFAMILY SSF52743 131 393 4.06E-74 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 347 357 - T 23-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 SUPERFAMILY SSF54897 52 122 6.8E-8 T 23-04-2016 IPR009020 Proteinase inhibitor, propeptide DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 PANTHER PTHR10795 10 399 3.5E-124 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 Gene3D G3DSA:3.30.70.80 46 126 2.6E-16 T 23-04-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 Pfam PF00082 Subtilase family 155 384 5.6E-39 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS30005 2f09e597940ca0eae29dd6ab2d93e8a4 403 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 197 207 - T 23-04-2016 IPR022398 Peptidase S8, subtilisin, His-active site DC74_RS28215 4bca19f00ecdabe5c94218f8e669db23 370 SUPERFAMILY SSF102114 115 343 3.27E-17 T 23-04-2016 DC74_RS28215 4bca19f00ecdabe5c94218f8e669db23 370 Pfam PF04055 Radical SAM superfamily 126 297 3.0E-16 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS28215 4bca19f00ecdabe5c94218f8e669db23 370 Gene3D G3DSA:3.20.20.70 122 332 1.2E-15 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS28215 4bca19f00ecdabe5c94218f8e669db23 370 PANTHER PTHR30544:SF5 3 370 2.9E-165 T 23-04-2016 DC74_RS28215 4bca19f00ecdabe5c94218f8e669db23 370 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 21 370 67.504 T 23-04-2016 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS28215 4bca19f00ecdabe5c94218f8e669db23 370 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 22 369 1.6E-95 T 23-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS28215 4bca19f00ecdabe5c94218f8e669db23 370 PANTHER PTHR30544 3 370 2.9E-165 T 23-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS28215 4bca19f00ecdabe5c94218f8e669db23 370 PIRSF PIRSF006004 16 370 4.8E-123 T 23-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS22765 712937abb67d6d55fa2118cf94b277a7 472 SUPERFAMILY SSF55486 242 466 7.91E-50 T 23-04-2016 DC74_RS22765 712937abb67d6d55fa2118cf94b277a7 472 Gene3D G3DSA:1.10.390.10 332 469 2.6E-25 T 23-04-2016 DC74_RS22765 712937abb67d6d55fa2118cf94b277a7 472 PANTHER PTHR11533 39 470 1.8E-88 T 23-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 DC74_RS22765 712937abb67d6d55fa2118cf94b277a7 472 Pfam PF01433 Peptidase family M1 55 360 3.0E-42 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS22765 712937abb67d6d55fa2118cf94b277a7 472 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 337 349 3.3E-10 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS22765 712937abb67d6d55fa2118cf94b277a7 472 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 217 232 3.3E-10 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS22765 712937abb67d6d55fa2118cf94b277a7 472 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 170 185 3.3E-10 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS22765 712937abb67d6d55fa2118cf94b277a7 472 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 318 333 3.3E-10 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS22765 712937abb67d6d55fa2118cf94b277a7 472 SUPERFAMILY SSF63737 42 233 7.19E-36 T 23-04-2016 DC74_RS22765 712937abb67d6d55fa2118cf94b277a7 472 PANTHER PTHR11533:SF185 39 470 1.8E-88 T 23-04-2016 DC74_RS13220 2eaa7f5e9886d0f1c07423bbe12e83f7 210 Pfam PF13673 Acetyltransferase (GNAT) domain 44 154 5.6E-8 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS13220 2eaa7f5e9886d0f1c07423bbe12e83f7 210 Gene3D G3DSA:3.40.630.30 2 160 1.6E-33 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS13220 2eaa7f5e9886d0f1c07423bbe12e83f7 210 SUPERFAMILY SSF55729 1 161 1.55E-20 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS39345 03d9fc140e77af41b05d9a27c2a099cb 196 Gene3D G3DSA:1.10.10.60 3 49 3.9E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39345 03d9fc140e77af41b05d9a27c2a099cb 196 PANTHER PTHR30055 3 189 1.6E-51 T 23-04-2016 DC74_RS39345 03d9fc140e77af41b05d9a27c2a099cb 196 SUPERFAMILY SSF46689 6 65 2.29E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39345 03d9fc140e77af41b05d9a27c2a099cb 196 SUPERFAMILY SSF48498 77 182 1.11E-17 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS39345 03d9fc140e77af41b05d9a27c2a099cb 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 46 3.4E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39345 03d9fc140e77af41b05d9a27c2a099cb 196 PANTHER PTHR30055:SF87 3 189 1.6E-51 T 23-04-2016 DC74_RS39345 03d9fc140e77af41b05d9a27c2a099cb 196 Gene3D G3DSA:1.10.357.10 51 185 6.9E-37 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS09265 cbc7eb737d4018fcd9670e0eabaef717 264 SMART SM00866 105 243 2.5E-14 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS09265 cbc7eb737d4018fcd9670e0eabaef717 264 PANTHER PTHR11751 11 75 1.0E-12 T 23-04-2016 DC74_RS09265 cbc7eb737d4018fcd9670e0eabaef717 264 PANTHER PTHR11751 224 248 1.0E-12 T 23-04-2016 DC74_RS09265 cbc7eb737d4018fcd9670e0eabaef717 264 Gene3D G3DSA:3.40.1410.10 74 246 3.0E-31 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS09265 cbc7eb737d4018fcd9670e0eabaef717 264 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 5.0E-13 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS09265 cbc7eb737d4018fcd9670e0eabaef717 264 SMART SM00345 14 73 6.9E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS09265 cbc7eb737d4018fcd9670e0eabaef717 264 SUPERFAMILY SSF64288 61 248 3.01E-22 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS09265 cbc7eb737d4018fcd9670e0eabaef717 264 PANTHER PTHR11751:SF333 11 75 1.0E-12 T 23-04-2016 DC74_RS09265 cbc7eb737d4018fcd9670e0eabaef717 264 PANTHER PTHR11751:SF333 224 248 1.0E-12 T 23-04-2016 DC74_RS09265 cbc7eb737d4018fcd9670e0eabaef717 264 Pfam PF07702 UTRA domain 112 242 1.3E-17 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS09265 cbc7eb737d4018fcd9670e0eabaef717 264 SUPERFAMILY SSF46785 3 77 2.72E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09265 cbc7eb737d4018fcd9670e0eabaef717 264 Gene3D G3DSA:1.10.10.10 4 73 3.7E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29930 2dadb0033de89decdf801869155911c1 219 Gene3D G3DSA:3.90.470.20 100 177 1.0E-6 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS29930 2dadb0033de89decdf801869155911c1 219 PANTHER PTHR38096 13 219 2.1E-59 T 23-04-2016 DC74_RS29930 2dadb0033de89decdf801869155911c1 219 SUPERFAMILY SSF56214 99 216 1.92E-16 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS29930 2dadb0033de89decdf801869155911c1 219 PRINTS PR01399 Enterobactin synthetase component D signature 67 85 2.5E-23 T 23-04-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UniPathway: UPA00017 DC74_RS29930 2dadb0033de89decdf801869155911c1 219 PRINTS PR01399 Enterobactin synthetase component D signature 37 57 2.5E-23 T 23-04-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UniPathway: UPA00017 DC74_RS29930 2dadb0033de89decdf801869155911c1 219 PRINTS PR01399 Enterobactin synthetase component D signature 145 161 2.5E-23 T 23-04-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UniPathway: UPA00017 DC74_RS29930 2dadb0033de89decdf801869155911c1 219 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 101 179 1.8E-12 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS26620 c62597a0a4335b1caa0251a1723b1bbb 253 SUPERFAMILY SSF53335 10 241 2.13E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS26620 c62597a0a4335b1caa0251a1723b1bbb 253 Gene3D G3DSA:3.40.50.150 10 242 2.6E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS26620 c62597a0a4335b1caa0251a1723b1bbb 253 Pfam PF13649 Methyltransferase domain 49 148 3.5E-16 T 23-04-2016 DC74_RS26620 c62597a0a4335b1caa0251a1723b1bbb 253 PANTHER PTHR10108:SF847 187 192 8.7E-33 T 23-04-2016 DC74_RS26620 c62597a0a4335b1caa0251a1723b1bbb 253 PANTHER PTHR10108:SF847 11 162 8.7E-33 T 23-04-2016 DC74_RS26620 c62597a0a4335b1caa0251a1723b1bbb 253 PANTHER PTHR10108 187 192 8.7E-33 T 23-04-2016 DC74_RS26620 c62597a0a4335b1caa0251a1723b1bbb 253 PANTHER PTHR10108 11 162 8.7E-33 T 23-04-2016 DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 Pfam PF03527 RHS protein 1350 1379 4.5E-7 T 23-04-2016 IPR001826 RHS protein DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 PANTHER PTHR32305:SF6 1173 1449 8.0E-108 T 23-04-2016 DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 PANTHER PTHR32305:SF6 540 1099 8.0E-108 T 23-04-2016 DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 Gene3D G3DSA:1.25.40.10 121 264 5.8E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 Pfam PF05593 RHS Repeat 630 659 1.1E-7 T 23-04-2016 IPR031325 RHS repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 Pfam PF05593 RHS Repeat 762 799 5.0E-9 T 23-04-2016 IPR031325 RHS repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 Pfam PF05593 RHS Repeat 783 820 4.2E-8 T 23-04-2016 IPR031325 RHS repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 Pfam PF05593 RHS Repeat 826 862 1.3E-7 T 23-04-2016 IPR031325 RHS repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 Pfam PF05593 RHS Repeat 972 1006 7.5E-5 T 23-04-2016 IPR031325 RHS repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 Pfam PF05593 RHS Repeat 935 964 6.7E-7 T 23-04-2016 IPR031325 RHS repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 Pfam PF05593 RHS Repeat 700 736 1.3E-5 T 23-04-2016 IPR031325 RHS repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 Pfam PF05593 RHS Repeat 994 1028 5.7E-5 T 23-04-2016 IPR031325 RHS repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 Pfam PF05593 RHS Repeat 1248 1280 9.8E-7 T 23-04-2016 IPR031325 RHS repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 Pfam PF05593 RHS Repeat 721 757 4.7E-10 T 23-04-2016 IPR031325 RHS repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 PANTHER PTHR32305 540 1099 8.0E-108 T 23-04-2016 DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1376 1449 2.6E-21 T 23-04-2016 IPR022385 Rhs repeat-associated core GO:0097264 DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 PANTHER PTHR32305 1173 1449 8.0E-108 T 23-04-2016 DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1163 1195 2.9E-4 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1248 1278 6.8E-6 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 930 970 3.5E-8 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 972 1006 8.3E-6 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 804 844 1.9E-10 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 762 803 7.2E-8 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 741 776 5.9E-7 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 888 923 7.4E-5 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 847 887 6.6E-6 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1037 1070 0.0019 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 700 740 5.6E-7 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 721 760 4.2E-10 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1053 1086 5.7E-5 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1013 1047 0.0021 T 23-04-2016 IPR006530 YD repeat DC74_RS21765 bee86cc3a7990c11f75f4ac51db52861 1593 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 608 646 1.7E-8 T 23-04-2016 IPR006530 YD repeat DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 Gene3D G3DSA:1.10.420.10 588 709 1.6E-45 T 23-04-2016 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 Gene3D G3DSA:1.10.520.10 228 251 1.5E-72 T 23-04-2016 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 Gene3D G3DSA:1.10.520.10 53 196 1.5E-72 T 23-04-2016 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 Gene3D G3DSA:1.10.420.10 311 408 3.5E-45 T 23-04-2016 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 Gene3D G3DSA:1.10.420.10 252 275 3.5E-45 T 23-04-2016 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 PANTHER PTHR30555:SF0 1 733 0.0 T 23-04-2016 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 260 270 - T 23-04-2016 IPR019793 Peroxidases heam-ligand binding site DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 PANTHER PTHR30555 1 733 0.0 T 23-04-2016 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 Pfam PF00141 Peroxidase 403 708 7.6E-39 T 23-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 Pfam PF00141 Peroxidase 88 396 3.6E-49 T 23-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 SUPERFAMILY SSF48113 431 733 2.8E-108 T 23-04-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 28 733 0.0 T 23-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 73 98 2.0E-51 T 23-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 58 71 2.0E-51 T 23-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 481 507 2.0E-51 T 23-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 268 291 2.0E-51 T 23-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 32 54 2.0E-51 T 23-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 SUPERFAMILY SSF48113 25 431 3.68E-156 T 23-04-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 Gene3D G3DSA:1.10.520.10 433 587 1.7E-60 T 23-04-2016 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 Gene3D G3DSA:1.10.520.10 712 734 1.7E-60 T 23-04-2016 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 PRINTS PR00458 Haem peroxidase superfamily signature 96 110 6.0E-20 T 23-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 PRINTS PR00458 Haem peroxidase superfamily signature 156 173 6.0E-20 T 23-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 PRINTS PR00458 Haem peroxidase superfamily signature 260 275 6.0E-20 T 23-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 PRINTS PR00458 Haem peroxidase superfamily signature 174 186 6.0E-20 T 23-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 PRINTS PR00458 Haem peroxidase superfamily signature 319 334 6.0E-20 T 23-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 ProSitePatterns PS00436 Peroxidases active site signature. 96 107 - T 23-04-2016 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 DC74_RS02045 f93538a8f3eaa61a368f3f51ae7d15ee 734 Hamap MF_01961 Catalase-peroxidase [katG]. 11 734 42.226 T 23-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 SUPERFAMILY SSF49503 62 204 5.5E-36 T 23-04-2016 IPR008972 Cupredoxin DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 Gene3D G3DSA:2.60.40.420 526 648 2.0E-41 T 23-04-2016 IPR008972 Cupredoxin DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 Gene3D G3DSA:2.60.40.420 57 183 2.0E-34 T 23-04-2016 IPR008972 Cupredoxin DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 SUPERFAMILY SSF49503 525 645 1.0E-33 T 23-04-2016 IPR008972 Cupredoxin DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 ProSitePatterns PS00080 Multicopper oxidases signature 2. 630 641 - T 23-04-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 PANTHER PTHR11709 396 645 4.0E-95 T 23-04-2016 DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 PANTHER PTHR11709 56 198 4.0E-95 T 23-04-2016 DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 PANTHER PTHR11709 262 283 4.0E-95 T 23-04-2016 DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 Pfam PF00394 Multicopper oxidase 397 500 9.3E-22 T 23-04-2016 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 Pfam PF07731 Multicopper oxidase 542 645 4.4E-25 T 23-04-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 SUPERFAMILY SSF49503 183 227 1.37E-27 T 23-04-2016 IPR008972 Cupredoxin DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 SUPERFAMILY SSF49503 395 510 1.37E-27 T 23-04-2016 IPR008972 Cupredoxin DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 PANTHER PTHR11709:SF33 396 645 4.0E-95 T 23-04-2016 DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 PANTHER PTHR11709:SF33 56 198 4.0E-95 T 23-04-2016 DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 PANTHER PTHR11709:SF33 262 283 4.0E-95 T 23-04-2016 DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 Pfam PF07732 Multicopper oxidase 75 181 7.4E-34 T 23-04-2016 IPR011707 Multicopper oxidase, type 3 GO:0005507 DC74_RS13305 02ac8eeab5b14125d7cbc95bf05b31cf 650 Gene3D G3DSA:2.60.40.420 364 512 1.3E-38 T 23-04-2016 IPR008972 Cupredoxin DC74_RS05760 e279054d9fefaaabdd4fe88c0eadd06c 139 SMART SM00387 39 139 2.7E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS05760 e279054d9fefaaabdd4fe88c0eadd06c 139 Gene3D G3DSA:3.30.565.10 12 134 6.1E-15 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS05760 e279054d9fefaaabdd4fe88c0eadd06c 139 SUPERFAMILY SSF55874 35 134 1.7E-15 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS05760 e279054d9fefaaabdd4fe88c0eadd06c 139 Pfam PF13581 Histidine kinase-like ATPase domain 19 134 2.6E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS39335 3cd7db9c962b98857158703c32af61c9 505 Gene3D G3DSA:3.20.20.80 64 385 5.9E-42 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS39335 3cd7db9c962b98857158703c32af61c9 505 PANTHER PTHR31308 91 233 4.8E-19 T 23-04-2016 DC74_RS39335 3cd7db9c962b98857158703c32af61c9 505 SUPERFAMILY SSF51445 73 164 1.67E-41 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS39335 3cd7db9c962b98857158703c32af61c9 505 SUPERFAMILY SSF51445 198 385 1.67E-41 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS39335 3cd7db9c962b98857158703c32af61c9 505 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 224 233 - T 23-04-2016 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 DC74_RS39335 3cd7db9c962b98857158703c32af61c9 505 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 70 385 2.0E-27 T 23-04-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 DC74_RS18950 72d8c38fb232e5810eabcd39038c6899 412 SUPERFAMILY SSF55874 283 391 1.05E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS18950 72d8c38fb232e5810eabcd39038c6899 412 Pfam PF13796 Putative sensor 36 152 6.4E-30 T 23-04-2016 IPR025828 Putative sensor domain DC74_RS18950 72d8c38fb232e5810eabcd39038c6899 412 Pfam PF07730 Histidine kinase 203 269 9.7E-11 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS18950 72d8c38fb232e5810eabcd39038c6899 412 PANTHER PTHR24421 130 406 8.3E-149 T 23-04-2016 DC74_RS18950 72d8c38fb232e5810eabcd39038c6899 412 PANTHER PTHR24421:SF13 130 406 8.3E-149 T 23-04-2016 DC74_RS18455 3108f9e6ad703dd43cce050f930e4a2b 110 Pfam PF02467 Transcription factor WhiB 17 87 6.5E-25 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS18455 3108f9e6ad703dd43cce050f930e4a2b 110 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 6 94 17.581 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS18455 3108f9e6ad703dd43cce050f930e4a2b 110 PANTHER PTHR38839 1 104 6.1E-63 T 23-04-2016 DC74_RS18455 3108f9e6ad703dd43cce050f930e4a2b 110 PANTHER PTHR38839:SF1 1 104 6.1E-63 T 23-04-2016 DC74_RS00655 08e0443d8863c9513fc9384e872f355d 125 SUPERFAMILY SSF51430 27 65 2.88E-6 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS00655 08e0443d8863c9513fc9384e872f355d 125 Gene3D G3DSA:3.20.20.100 27 66 1.8E-6 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS26780 a2742ca969b17602209f0ca0943c6668 376 SUPERFAMILY SSF47240 96 325 1.56E-67 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS26780 a2742ca969b17602209f0ca0943c6668 376 Gene3D G3DSA:1.10.620.20 46 261 2.1E-17 T 23-04-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 DC74_RS26780 a2742ca969b17602209f0ca0943c6668 376 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 46 312 4.9E-16 T 23-04-2016 IPR025859 P-aminobenzoate N-oxygenase AurF DC74_RS33530 89f5d012287c559be2e3a2779c461571 211 Pfam PF01476 LysM domain 161 205 9.4E-6 T 23-04-2016 IPR018392 LysM domain DC74_RS33530 89f5d012287c559be2e3a2779c461571 211 SUPERFAMILY SSF54106 159 206 2.62E-7 T 23-04-2016 IPR018392 LysM domain DC74_RS33530 89f5d012287c559be2e3a2779c461571 211 Gene3D G3DSA:1.10.530.10 10 113 9.2E-41 T 23-04-2016 DC74_RS33530 89f5d012287c559be2e3a2779c461571 211 Gene3D G3DSA:3.10.350.10 161 205 4.7E-9 T 23-04-2016 IPR018392 LysM domain DC74_RS33530 89f5d012287c559be2e3a2779c461571 211 Pfam PF06737 Transglycosylase-like domain 32 107 9.0E-33 T 23-04-2016 IPR010618 Transglycosylase-like DC74_RS33530 89f5d012287c559be2e3a2779c461571 211 SUPERFAMILY SSF53955 32 113 3.15E-31 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS33530 89f5d012287c559be2e3a2779c461571 211 SMART SM00257 159 206 2.2E-5 T 23-04-2016 IPR018392 LysM domain DC74_RS15290 f889ba28f99a3e8f803e650e6545ee0a 486 SUPERFAMILY SSF53623 52 341 2.65E-89 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS15290 f889ba28f99a3e8f803e650e6545ee0a 486 SUPERFAMILY SSF53244 346 484 8.97E-28 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS15290 f889ba28f99a3e8f803e650e6545ee0a 486 Pfam PF02875 Mur ligase family, glutamate ligase domain 345 424 1.4E-11 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS15290 f889ba28f99a3e8f803e650e6545ee0a 486 Gene3D G3DSA:3.40.1190.10 63 343 1.7E-95 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS15290 f889ba28f99a3e8f803e650e6545ee0a 486 Gene3D G3DSA:3.90.190.20 346 485 5.7E-39 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 DC74_RS15290 f889ba28f99a3e8f803e650e6545ee0a 486 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 185 200 - T 23-04-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 DC74_RS15290 f889ba28f99a3e8f803e650e6545ee0a 486 PANTHER PTHR11136:SF0 63 486 1.7E-127 T 23-04-2016 DC74_RS15290 f889ba28f99a3e8f803e650e6545ee0a 486 PANTHER PTHR11136 63 486 1.7E-127 T 23-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 DC74_RS15290 f889ba28f99a3e8f803e650e6545ee0a 486 Pfam PF08245 Mur ligase middle domain 89 316 9.9E-16 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 DC74_RS15290 f889ba28f99a3e8f803e650e6545ee0a 486 TIGRFAM TIGR01499 folC: bifunctional protein FolC 68 480 1.0E-98 T 23-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 DC74_RS16120 2d29e06d76040c2ea9cff71b0bff2107 250 PANTHER PTHR30136:SF3 6 218 1.6E-58 T 23-04-2016 DC74_RS16120 2d29e06d76040c2ea9cff71b0bff2107 250 PANTHER PTHR30136 6 218 1.6E-58 T 23-04-2016 DC74_RS16120 2d29e06d76040c2ea9cff71b0bff2107 250 SUPERFAMILY SSF55781 77 212 6.47E-20 T 23-04-2016 IPR029016 GAF domain-like DC74_RS16120 2d29e06d76040c2ea9cff71b0bff2107 250 Pfam PF09339 IclR helix-turn-helix domain 14 62 1.9E-7 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS16120 2d29e06d76040c2ea9cff71b0bff2107 250 SMART SM00346 11 100 5.7E-5 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS16120 2d29e06d76040c2ea9cff71b0bff2107 250 Pfam PF01614 Bacterial transcriptional regulator 137 211 2.9E-13 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS16120 2d29e06d76040c2ea9cff71b0bff2107 250 Gene3D G3DSA:1.10.10.10 12 84 1.6E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16120 2d29e06d76040c2ea9cff71b0bff2107 250 SUPERFAMILY SSF46785 12 81 2.18E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16120 2d29e06d76040c2ea9cff71b0bff2107 250 Gene3D G3DSA:3.30.450.40 87 214 1.7E-21 T 23-04-2016 IPR029016 GAF domain-like DC74_RS11375 7eacd744a08ae0f59c2e1772145faf44 257 PANTHER PTHR31885 72 234 3.4E-19 T 23-04-2016 DC74_RS11375 7eacd744a08ae0f59c2e1772145faf44 257 Pfam PF07947 YhhN-like protein 51 233 3.9E-32 T 23-04-2016 IPR012506 YhhN-like GO:0016021 DC74_RS20595 14745caeb76fb7f0bc63f3628d75f411 229 Pfam PF04203 Sortase family 82 213 7.6E-27 T 23-04-2016 IPR005754 Sortase family DC74_RS20595 14745caeb76fb7f0bc63f3628d75f411 229 SUPERFAMILY SSF63817 72 217 3.01E-31 T 23-04-2016 IPR023365 Sortase domain DC74_RS20595 14745caeb76fb7f0bc63f3628d75f411 229 TIGRFAM TIGR01076 sortase_fam: sortase 90 212 1.7E-14 T 23-04-2016 IPR005754 Sortase family DC74_RS20595 14745caeb76fb7f0bc63f3628d75f411 229 Gene3D G3DSA:2.40.260.10 79 217 4.9E-25 T 23-04-2016 IPR023365 Sortase domain DC74_RS20595 14745caeb76fb7f0bc63f3628d75f411 229 PANTHER PTHR33393:SF3 6 227 1.5E-25 T 23-04-2016 DC74_RS20595 14745caeb76fb7f0bc63f3628d75f411 229 PANTHER PTHR33393 6 227 1.5E-25 T 23-04-2016 DC74_RS05330 3f81465ee102e68a0c4c2447c9b4d330 542 Gene3D G3DSA:3.20.20.70 23 237 2.4E-12 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS05330 3f81465ee102e68a0c4c2447c9b4d330 542 SUPERFAMILY SSF51735 352 505 7.66E-22 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05330 3f81465ee102e68a0c4c2447c9b4d330 542 PANTHER PTHR21089 199 520 5.3E-47 T 23-04-2016 DC74_RS05330 3f81465ee102e68a0c4c2447c9b4d330 542 SUPERFAMILY SSF51569 33 239 6.59E-13 T 23-04-2016 DC74_RS05330 3f81465ee102e68a0c4c2447c9b4d330 542 SUPERFAMILY SSF53223 249 351 2.3E-16 T 23-04-2016 DC74_RS05330 3f81465ee102e68a0c4c2447c9b4d330 542 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 255 339 5.1E-10 T 23-04-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS05330 3f81465ee102e68a0c4c2447c9b4d330 542 PANTHER PTHR21089:SF1 199 520 5.3E-47 T 23-04-2016 DC74_RS05330 3f81465ee102e68a0c4c2447c9b4d330 542 Gene3D G3DSA:3.40.192.10 250 371 2.2E-25 T 23-04-2016 DC74_RS05330 3f81465ee102e68a0c4c2447c9b4d330 542 Gene3D G3DSA:3.40.50.720 372 480 3.8E-19 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05330 3f81465ee102e68a0c4c2447c9b4d330 542 Pfam PF01487 Type I 3-dehydroquinase 39 237 2.5E-10 T 23-04-2016 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 DC74_RS21905 c91c53768b1e230fc1b1ee647c58de43 252 Gene3D G3DSA:3.90.550.10 7 230 3.3E-26 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS21905 c91c53768b1e230fc1b1ee647c58de43 252 PANTHER PTHR22916 2 248 5.3E-26 T 23-04-2016 DC74_RS21905 c91c53768b1e230fc1b1ee647c58de43 252 SUPERFAMILY SSF53448 16 218 3.02E-26 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS21905 c91c53768b1e230fc1b1ee647c58de43 252 Pfam PF00535 Glycosyl transferase family 2 7 109 2.3E-10 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 SUPERFAMILY SSF55874 269 419 4.32E-32 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 SMART SM00388 200 266 4.5E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 Gene3D G3DSA:1.10.287.130 190 262 5.8E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 374 1.2E-8 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 399 1.2E-8 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 418 1.2E-8 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 1.2E-8 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 PANTHER PTHR24423 28 34 1.6E-65 T 23-04-2016 DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 PANTHER PTHR24423 140 419 1.6E-65 T 23-04-2016 DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 SUPERFAMILY SSF158472 147 196 1.11E-8 T 23-04-2016 DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 SMART SM00387 308 419 6.0E-25 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 Pfam PF00672 HAMP domain 128 195 5.0E-14 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 Gene3D G3DSA:3.30.565.10 269 419 4.6E-35 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 SMART SM00304 146 199 1.7E-12 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 SUPERFAMILY SSF47384 183 265 9.61E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 419 9.6E-16 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS38195 e08ee36f8fe53ac9d32f473a0d290dbb 419 Pfam PF00512 His Kinase A (phospho-acceptor) domain 200 265 4.7E-10 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 SUPERFAMILY SSF53474 816 853 1.99E-29 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 SUPERFAMILY SSF53474 946 1176 1.99E-29 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 SMART SM00826 1 153 2.4E-33 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 Gene3D G3DSA:1.10.1200.10 783 856 2.3E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 ProSitePatterns PS00012 Phosphopantetheine attachment site. 812 827 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 SUPERFAMILY SSF51735 294 496 1.61E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 PANTHER PTHR11712 3 407 1.7E-145 T 23-04-2016 DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 SMART SM01294 785 853 0.0017 T 23-04-2016 DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 SMART SM00824 Thioesterase 971 1176 2.0E-91 T 23-04-2016 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 Pfam PF14765 Polyketide synthase dehydratase 3 278 2.7E-46 T 23-04-2016 IPR020807 Polyketide synthase, dehydratase domain DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 PANTHER PTHR11712 427 856 1.7E-145 T 23-04-2016 DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 Pfam PF08659 KR domain 512 690 1.7E-58 T 23-04-2016 IPR013968 Polyketide synthase, ketoreductase domain DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 512 692 2.3E-55 T 23-04-2016 DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 Pfam PF00975 Thioesterase domain 978 1170 2.3E-16 T 23-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 Pfam PF00550 Phosphopantetheine attachment site 786 852 2.7E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 PANTHER PTHR11712:SF242 3 407 1.7E-145 T 23-04-2016 DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 SMART SM00823 Phosphopantetheine attachment site 784 857 1.5E-22 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 PANTHER PTHR11712:SF242 427 856 1.7E-145 T 23-04-2016 DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 Gene3D G3DSA:3.40.50.720 512 723 7.2E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 SUPERFAMILY SSF51735 510 744 4.32E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 Gene3D G3DSA:3.40.50.1820 915 1176 1.9E-68 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01095 939b8a5a7257259fe4b412a0039cc10d 1181 SUPERFAMILY SSF47336 781 871 7.77E-19 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 72 262 3.4E-41 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 Pfam PF00717 Peptidase S24-like 93 135 7.3E-13 T 23-04-2016 IPR019759 Peptidase S24/S26A/S26B DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 SUPERFAMILY SSF51306 163 268 6.8E-48 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 SUPERFAMILY SSF51306 85 133 6.8E-48 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 PANTHER PTHR12383:SF14 166 273 1.0E-65 T 23-04-2016 DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 PANTHER PTHR12383:SF14 47 132 1.0E-65 T 23-04-2016 DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 ProSitePatterns PS00761 Signal peptidases I signature 3. 221 234 - T 23-04-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 Gene3D G3DSA:2.10.109.10 216 273 1.9E-40 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 Gene3D G3DSA:2.10.109.10 83 178 1.9E-40 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 PANTHER PTHR12383 166 273 1.0E-65 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 PANTHER PTHR12383 47 132 1.0E-65 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 Pfam PF10502 Signal peptidase, peptidase S26 164 257 2.4E-10 T 23-04-2016 IPR019533 Peptidase S26 DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 86 102 8.2E-20 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 168 180 8.2E-20 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28140 fcca2ee1089dc5eac513d362021fca9d 353 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 216 235 8.2E-20 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS31515 31e11f3460689103c53cbc201c881d9e 373 SUPERFAMILY SSF53067 37 348 2.07E-67 T 23-04-2016 DC74_RS31515 31e11f3460689103c53cbc201c881d9e 373 ProSitePatterns PS01125 ROK family signature. 166 193 - T 23-04-2016 IPR000600 ROK family DC74_RS31515 31e11f3460689103c53cbc201c881d9e 373 Gene3D G3DSA:3.30.420.40 37 171 8.0E-44 T 23-04-2016 DC74_RS31515 31e11f3460689103c53cbc201c881d9e 373 PANTHER PTHR18964:SF108 16 231 1.6E-108 T 23-04-2016 DC74_RS31515 31e11f3460689103c53cbc201c881d9e 373 PANTHER PTHR18964:SF108 251 347 1.6E-108 T 23-04-2016 DC74_RS31515 31e11f3460689103c53cbc201c881d9e 373 Gene3D G3DSA:3.30.420.40 172 320 3.6E-50 T 23-04-2016 DC74_RS31515 31e11f3460689103c53cbc201c881d9e 373 PANTHER PTHR18964 16 231 1.6E-108 T 23-04-2016 DC74_RS31515 31e11f3460689103c53cbc201c881d9e 373 PANTHER PTHR18964 251 347 1.6E-108 T 23-04-2016 DC74_RS31515 31e11f3460689103c53cbc201c881d9e 373 Pfam PF00480 ROK family 37 347 1.4E-79 T 23-04-2016 IPR000600 ROK family DC74_RS31515 31e11f3460689103c53cbc201c881d9e 373 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 38 347 1.0E-89 T 23-04-2016 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 DC74_RS33675 b2f072c718b46cf3bb0a60b61d506ab1 246 SMART SM00421 162 219 5.8E-4 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS33675 b2f072c718b46cf3bb0a60b61d506ab1 246 Gene3D G3DSA:1.10.10.10 166 224 2.6E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS33675 b2f072c718b46cf3bb0a60b61d506ab1 246 SUPERFAMILY SSF46894 165 225 1.29E-9 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS33675 b2f072c718b46cf3bb0a60b61d506ab1 246 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 38 115 1.7E-5 T 23-04-2016 IPR000014 PAS domain DC74_RS33675 b2f072c718b46cf3bb0a60b61d506ab1 246 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 218 8.6E-6 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS33675 b2f072c718b46cf3bb0a60b61d506ab1 246 Pfam PF00989 PAS fold 42 137 4.3E-10 T 23-04-2016 IPR013767 PAS fold GO:0006355 DC74_RS33675 b2f072c718b46cf3bb0a60b61d506ab1 246 Gene3D G3DSA:3.30.450.20 39 137 2.7E-12 T 23-04-2016 DC74_RS33675 b2f072c718b46cf3bb0a60b61d506ab1 246 SMART SM00091 37 103 6.0E-7 T 23-04-2016 IPR000014 PAS domain DC74_RS33675 b2f072c718b46cf3bb0a60b61d506ab1 246 SUPERFAMILY SSF55785 36 135 7.68E-13 T 23-04-2016 IPR000014 PAS domain DC74_RS34335 2e02b8a000c35a4c14a33d14cb2972fe 346 PANTHER PTHR12862 11 339 1.1E-73 T 23-04-2016 DC74_RS34335 2e02b8a000c35a4c14a33d14cb2972fe 346 PANTHER PTHR12862:SF5 11 339 1.1E-73 T 23-04-2016 DC74_RS34335 2e02b8a000c35a4c14a33d14cb2972fe 346 SUPERFAMILY SSF53067 132 323 6.82E-40 T 23-04-2016 DC74_RS34335 2e02b8a000c35a4c14a33d14cb2972fe 346 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 14 278 3.8E-17 T 23-04-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type DC74_RS34335 2e02b8a000c35a4c14a33d14cb2972fe 346 Gene3D G3DSA:3.30.420.40 238 299 5.0E-5 T 23-04-2016 DC74_RS34335 2e02b8a000c35a4c14a33d14cb2972fe 346 Gene3D G3DSA:3.30.420.40 179 203 5.0E-5 T 23-04-2016 DC74_RS25680 8833ff2e83b97e53a0d4fbd24418648b 786 PANTHER PTHR11070 261 752 2.5E-49 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 DC74_RS25680 8833ff2e83b97e53a0d4fbd24418648b 786 Pfam PF13361 UvrD-like helicase C-terminal domain 681 752 1.7E-14 T 23-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 DC74_RS25680 8833ff2e83b97e53a0d4fbd24418648b 786 SUPERFAMILY SSF52540 484 755 1.21E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25680 8833ff2e83b97e53a0d4fbd24418648b 786 SUPERFAMILY SSF52540 264 390 1.21E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25680 8833ff2e83b97e53a0d4fbd24418648b 786 SUPERFAMILY SSF52540 429 456 1.21E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25680 8833ff2e83b97e53a0d4fbd24418648b 786 Pfam PF13245 Part of AAA domain 284 353 8.5E-12 T 23-04-2016 DC74_RS25680 8833ff2e83b97e53a0d4fbd24418648b 786 Pfam PF00580 UvrD/REP helicase N-terminal domain 500 546 6.3E-10 T 23-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 DC74_RS25680 8833ff2e83b97e53a0d4fbd24418648b 786 Gene3D G3DSA:3.40.50.300 478 570 3.3E-30 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25680 8833ff2e83b97e53a0d4fbd24418648b 786 Gene3D G3DSA:3.40.50.300 268 372 3.3E-30 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25680 8833ff2e83b97e53a0d4fbd24418648b 786 Gene3D G3DSA:3.40.50.300 571 761 2.3E-31 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20825 62f43d9ff2f8c30107997ee1dd1ba6c6 203 Pfam PF00436 Single-strand binding protein family 7 107 2.1E-30 T 23-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 DC74_RS20825 62f43d9ff2f8c30107997ee1dd1ba6c6 203 PANTHER PTHR10302 7 161 1.7E-30 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 DC74_RS20825 62f43d9ff2f8c30107997ee1dd1ba6c6 203 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 123 1.8E-29 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 DC74_RS20825 62f43d9ff2f8c30107997ee1dd1ba6c6 203 SUPERFAMILY SSF50249 6 203 9.3E-40 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS20825 62f43d9ff2f8c30107997ee1dd1ba6c6 203 Gene3D G3DSA:2.40.50.140 4 116 1.0E-40 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS20825 62f43d9ff2f8c30107997ee1dd1ba6c6 203 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 30.256 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 DC74_RS23430 6cc9305a63d5086dd82e393e5ada8cbe 214 Pfam PF13599 Pentapeptide repeats (9 copies) 46 118 9.3E-7 T 23-04-2016 IPR001646 Pentapeptide repeat DC74_RS23430 6cc9305a63d5086dd82e393e5ada8cbe 214 Pfam PF00805 Pentapeptide repeats (8 copies) 136 175 4.3E-9 T 23-04-2016 IPR001646 Pentapeptide repeat DC74_RS23430 6cc9305a63d5086dd82e393e5ada8cbe 214 SUPERFAMILY SSF141571 32 205 1.37E-34 T 23-04-2016 DC74_RS23430 6cc9305a63d5086dd82e393e5ada8cbe 214 PANTHER PTHR14136:SF12 22 180 2.2E-14 T 23-04-2016 DC74_RS23430 6cc9305a63d5086dd82e393e5ada8cbe 214 PANTHER PTHR14136 22 180 2.2E-14 T 23-04-2016 DC74_RS11720 f1a30715df3ed27a34b3f763fd2a4211 254 PANTHER PTHR24220 5 245 8.0E-125 T 23-04-2016 DC74_RS11720 f1a30715df3ed27a34b3f763fd2a4211 254 Pfam PF00005 ABC transporter 23 174 6.0E-22 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS11720 f1a30715df3ed27a34b3f763fd2a4211 254 Gene3D G3DSA:3.40.50.300 3 235 5.4E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11720 f1a30715df3ed27a34b3f763fd2a4211 254 SUPERFAMILY SSF52540 4 234 1.36E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11720 f1a30715df3ed27a34b3f763fd2a4211 254 SMART SM00382 32 226 4.7E-5 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS11720 f1a30715df3ed27a34b3f763fd2a4211 254 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 245 1.4E-104 T 23-04-2016 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 DC74_RS11720 f1a30715df3ed27a34b3f763fd2a4211 254 PANTHER PTHR24220:SF85 5 245 8.0E-125 T 23-04-2016 DC74_RS00975 f281f10ce041252abf68e75788bbdac2 200 Gene3D G3DSA:1.10.357.10 10 193 3.8E-32 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS00975 f281f10ce041252abf68e75788bbdac2 200 PANTHER PTHR30055 1 198 1.9E-21 T 23-04-2016 DC74_RS00975 f281f10ce041252abf68e75788bbdac2 200 SUPERFAMILY SSF48498 85 196 5.76E-11 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS00975 f281f10ce041252abf68e75788bbdac2 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 63 6.3E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00975 f281f10ce041252abf68e75788bbdac2 200 SUPERFAMILY SSF46689 5 80 6.67E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS38955 dcc96967e1008c1912c1c5b867073111 309 PANTHER PTHR14194 1 309 8.3E-39 T 23-04-2016 DC74_RS38955 dcc96967e1008c1912c1c5b867073111 309 Gene3D G3DSA:3.40.50.720 8 238 3.8E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38955 dcc96967e1008c1912c1c5b867073111 309 SUPERFAMILY SSF51735 10 275 1.41E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38955 dcc96967e1008c1912c1c5b867073111 309 Pfam PF13460 NAD(P)H-binding 19 205 1.1E-20 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39460 f538d4539273c8c6e320e9452840b9b9 244 PANTHER PTHR24260:SF50 39 242 1.2E-14 T 23-04-2016 DC74_RS39460 f538d4539273c8c6e320e9452840b9b9 244 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 53 68 1.3E-5 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS39460 f538d4539273c8c6e320e9452840b9b9 244 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 106 120 1.3E-5 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS39460 f538d4539273c8c6e320e9452840b9b9 244 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 191 203 1.3E-5 T 23-04-2016 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 DC74_RS39460 f538d4539273c8c6e320e9452840b9b9 244 SUPERFAMILY SSF50494 9 243 5.68E-27 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS39460 f538d4539273c8c6e320e9452840b9b9 244 Gene3D G3DSA:2.40.10.10 61 243 1.5E-16 T 23-04-2016 DC74_RS39460 f538d4539273c8c6e320e9452840b9b9 244 Pfam PF00089 Trypsin 35 227 1.9E-19 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS39460 f538d4539273c8c6e320e9452840b9b9 244 PANTHER PTHR24260 39 242 1.2E-14 T 23-04-2016 DC74_RS39460 f538d4539273c8c6e320e9452840b9b9 244 SMART SM00020 28 238 2.8E-7 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS39460 f538d4539273c8c6e320e9452840b9b9 244 Gene3D G3DSA:2.40.10.10 30 60 1.2E-7 T 23-04-2016 DC74_RS39460 f538d4539273c8c6e320e9452840b9b9 244 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 63 68 - T 23-04-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 Gene3D G3DSA:3.40.50.300 336 552 5.1E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 266 3.3E-16 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 PANTHER PTHR24220 340 554 1.2E-76 T 23-04-2016 DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 SMART SM00382 346 529 1.0E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 67 270 3.0E-64 T 23-04-2016 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 Pfam PF03459 TOBE domain 605 667 2.8E-13 T 23-04-2016 IPR005116 Transport-associated OB, type 1 DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 Gene3D G3DSA:1.10.3720.10 26 268 6.2E-43 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 ProSitePatterns PS00211 ABC transporters family signature. 452 466 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 44 267 3.8E-69 T 23-04-2016 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 Pfam PF00005 ABC transporter 339 479 5.8E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 SUPERFAMILY SSF50331 554 667 1.72E-20 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 SUPERFAMILY SSF52540 338 554 1.97E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 Gene3D G3DSA:2.40.50.100 603 668 4.6E-17 T 23-04-2016 DC74_RS07310 37e41af3b11921c05220f510068ca3d1 670 SUPERFAMILY SSF161098 24 268 5.36E-49 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS10225 83b78bc92975362615575aa5fa623526 233 Pfam PF13411 MerR HTH family regulatory protein 1 69 1.0E-17 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS10225 83b78bc92975362615575aa5fa623526 233 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.4E-8 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS10225 83b78bc92975362615575aa5fa623526 233 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.4E-8 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS10225 83b78bc92975362615575aa5fa623526 233 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.4E-8 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS10225 83b78bc92975362615575aa5fa623526 233 SMART SM00422 1 71 2.0E-8 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS10225 83b78bc92975362615575aa5fa623526 233 PANTHER PTHR30204:SF1 1 73 1.1E-13 T 23-04-2016 DC74_RS10225 83b78bc92975362615575aa5fa623526 233 SUPERFAMILY SSF46955 1 89 4.4E-16 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS10225 83b78bc92975362615575aa5fa623526 233 PANTHER PTHR30204 1 73 1.1E-13 T 23-04-2016 DC74_RS10225 83b78bc92975362615575aa5fa623526 233 Gene3D G3DSA:1.10.1660.10 1 123 2.1E-19 T 23-04-2016 DC74_RS26630 7dba8cda7907c9e8a399d3e39906009c 312 PANTHER PTHR30450 52 291 4.0E-144 T 23-04-2016 DC74_RS26630 7dba8cda7907c9e8a399d3e39906009c 312 Gene3D G3DSA:1.10.3720.10 68 282 2.5E-49 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26630 7dba8cda7907c9e8a399d3e39906009c 312 SUPERFAMILY SSF161098 69 268 3.53E-44 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26630 7dba8cda7907c9e8a399d3e39906009c 312 PANTHER PTHR30450:SF2 52 291 4.0E-144 T 23-04-2016 DC74_RS26630 7dba8cda7907c9e8a399d3e39906009c 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 280 3.0E-21 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26630 7dba8cda7907c9e8a399d3e39906009c 312 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 69 177 2.5E-20 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 DC74_RS19585 e92038c3764a67b24c6ae9046d074641 321 SUPERFAMILY SSF51430 18 319 1.83E-79 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS19585 e92038c3764a67b24c6ae9046d074641 321 PANTHER PTHR11732:SF132 11 319 1.7E-145 T 23-04-2016 DC74_RS19585 e92038c3764a67b24c6ae9046d074641 321 Gene3D G3DSA:3.20.20.100 19 319 4.4E-81 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS19585 e92038c3764a67b24c6ae9046d074641 321 Pfam PF00248 Aldo/keto reductase family 23 319 2.8E-63 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS19585 e92038c3764a67b24c6ae9046d074641 321 PANTHER PTHR11732 11 319 1.7E-145 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS10930 6e24a6e6fb0a7a2d625ef9f4b77d66fa 141 SMART SM00960 13 103 3.6E-26 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS10930 6e24a6e6fb0a7a2d625ef9f4b77d66fa 141 Pfam PF03259 Roadblock/LC7 domain 13 103 1.0E-19 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS10930 6e24a6e6fb0a7a2d625ef9f4b77d66fa 141 PANTHER PTHR36222 1 141 8.6E-36 T 23-04-2016 DC74_RS10930 6e24a6e6fb0a7a2d625ef9f4b77d66fa 141 SUPERFAMILY SSF103196 7 128 1.26E-28 T 23-04-2016 DC74_RS10930 6e24a6e6fb0a7a2d625ef9f4b77d66fa 141 Gene3D G3DSA:3.30.450.30 8 127 1.1E-21 T 23-04-2016 DC74_RS33800 709b5508940f04350cab0f7de2a34c63 321 SUPERFAMILY SSF52540 7 233 3.48E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33800 709b5508940f04350cab0f7de2a34c63 321 PANTHER PTHR24220:SF442 6 297 1.1E-90 T 23-04-2016 DC74_RS33800 709b5508940f04350cab0f7de2a34c63 321 Pfam PF00005 ABC transporter 12 171 1.8E-18 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS33800 709b5508940f04350cab0f7de2a34c63 321 PANTHER PTHR24220 6 297 1.1E-90 T 23-04-2016 DC74_RS33800 709b5508940f04350cab0f7de2a34c63 321 SMART SM00382 19 230 2.0E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS33800 709b5508940f04350cab0f7de2a34c63 321 Gene3D G3DSA:3.40.50.300 6 254 1.4E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33800 709b5508940f04350cab0f7de2a34c63 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 298 1.2E-15 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS33800 709b5508940f04350cab0f7de2a34c63 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 293 4.3E-10 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 SUPERFAMILY SSF51621 3 895 1.35E-268 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 Gene3D G3DSA:1.20.1440.90 258 380 9.2E-25 T 23-04-2016 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 Pfam PF00311 Phosphoenolpyruvate carboxylase 113 895 5.7E-284 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 118 129 - T 23-04-2016 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 PANTHER PTHR30523 1 895 0.0 T 23-04-2016 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 378 398 1.9E-57 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 223 238 1.9E-57 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 721 747 1.9E-57 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 117 130 1.9E-57 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 542 562 1.9E-57 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 165 181 1.9E-57 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 584 613 1.9E-57 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 544 556 - T 23-04-2016 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 1 895 17.859 T 23-04-2016 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DC74_RS17510 4edda8a6ab680bfb74164d9a33c6adba 895 PANTHER PTHR30523:SF0 1 895 0.0 T 23-04-2016 DC74_RS20875 83fcbbf5de21bd8097e410656c628caf 376 Pfam PF13411 MerR HTH family regulatory protein 10 76 4.7E-11 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS20875 83fcbbf5de21bd8097e410656c628caf 376 Gene3D G3DSA:3.10.150.10 287 374 2.6E-8 T 23-04-2016 DC74_RS20875 83fcbbf5de21bd8097e410656c628caf 376 SMART SM00422 8 78 9.3E-10 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS20875 83fcbbf5de21bd8097e410656c628caf 376 Gene3D G3DSA:1.10.1660.10 10 103 1.6E-19 T 23-04-2016 DC74_RS20875 83fcbbf5de21bd8097e410656c628caf 376 SUPERFAMILY SSF46955 8 102 3.22E-18 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS20875 83fcbbf5de21bd8097e410656c628caf 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 187 2.4E-4 T 23-04-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS20875 83fcbbf5de21bd8097e410656c628caf 376 ProSitePatterns PS00552 MerR-type HTH domain signature. 11 33 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS20875 83fcbbf5de21bd8097e410656c628caf 376 PANTHER PTHR30204:SF22 3 105 6.3E-19 T 23-04-2016 DC74_RS20875 83fcbbf5de21bd8097e410656c628caf 376 Gene3D G3DSA:3.10.150.10 125 236 9.9E-10 T 23-04-2016 DC74_RS20875 83fcbbf5de21bd8097e410656c628caf 376 SUPERFAMILY SSF55979 314 374 1.32E-6 T 23-04-2016 DC74_RS20875 83fcbbf5de21bd8097e410656c628caf 376 PANTHER PTHR30204 3 105 6.3E-19 T 23-04-2016 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 SUPERFAMILY SSF53067 4 317 2.16E-36 T 23-04-2016 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 PANTHER PTHR11735:SF6 6 342 1.8E-125 T 23-04-2016 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 6 320 1.1E-118 T 23-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 Gene3D G3DSA:3.30.420.40 6 146 5.1E-43 T 23-04-2016 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 PANTHER PTHR11735 6 342 1.8E-125 T 23-04-2016 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 315 5.5E-91 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 ProSitePatterns PS01016 Glycoprotease family signature. 98 118 - T 23-04-2016 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 Pfam PF00814 Glycoprotease family 26 315 7.8E-90 T 23-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 341 58.115 T 23-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 133 145 1.6E-48 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 272 281 1.6E-48 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 99 118 1.6E-48 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 1.6E-48 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 78 98 1.6E-48 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS20190 23df1779acda9d5723efcea16cafd5aa 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 1.6E-48 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 DC74_RS32865 9fe89a36c63bf09aab958e4c516bcd92 747 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 398 423 - T 23-04-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 DC74_RS32865 9fe89a36c63bf09aab958e4c516bcd92 747 Gene3D G3DSA:3.20.20.240 55 576 2.6E-253 T 23-04-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 DC74_RS32865 9fe89a36c63bf09aab958e4c516bcd92 747 Pfam PF02310 B12 binding domain 616 726 8.6E-15 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS32865 9fe89a36c63bf09aab958e4c516bcd92 747 Gene3D G3DSA:3.40.50.280 580 739 2.0E-69 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS32865 9fe89a36c63bf09aab958e4c516bcd92 747 PANTHER PTHR23408:SF1 52 720 0.0 T 23-04-2016 DC74_RS32865 9fe89a36c63bf09aab958e4c516bcd92 747 Pfam PF01642 Methylmalonyl-CoA mutase 56 574 3.7E-236 T 23-04-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 DC74_RS32865 9fe89a36c63bf09aab958e4c516bcd92 747 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 55 581 1.6E-281 T 23-04-2016 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 DC74_RS32865 9fe89a36c63bf09aab958e4c516bcd92 747 SUPERFAMILY SSF51703 37 576 4.97E-223 T 23-04-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 DC74_RS32865 9fe89a36c63bf09aab958e4c516bcd92 747 SUPERFAMILY SSF52242 579 740 1.44E-57 T 23-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 DC74_RS32865 9fe89a36c63bf09aab958e4c516bcd92 747 PANTHER PTHR23408 52 720 0.0 T 23-04-2016 DC74_RS32865 9fe89a36c63bf09aab958e4c516bcd92 747 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 613 741 1.4E-59 T 23-04-2016 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 DC74_RS06995 32ac1ca7f4c25a2d8ba3ed3aea4f0a63 170 SUPERFAMILY SSF55729 8 133 3.6E-23 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06995 32ac1ca7f4c25a2d8ba3ed3aea4f0a63 170 PANTHER PTHR23091 5 165 2.6E-33 T 23-04-2016 DC74_RS06995 32ac1ca7f4c25a2d8ba3ed3aea4f0a63 170 PANTHER PTHR23091:SF235 5 165 2.6E-33 T 23-04-2016 DC74_RS06995 32ac1ca7f4c25a2d8ba3ed3aea4f0a63 170 Pfam PF00583 Acetyltransferase (GNAT) family 57 127 9.5E-9 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS06995 32ac1ca7f4c25a2d8ba3ed3aea4f0a63 170 Gene3D G3DSA:3.40.630.30 6 131 1.2E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31135 8e662e9935e08d57647695680824ad42 260 Gene3D G3DSA:1.20.120.530 125 259 3.4E-20 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS31135 8e662e9935e08d57647695680824ad42 260 PANTHER PTHR11751 61 147 1.4E-23 T 23-04-2016 DC74_RS31135 8e662e9935e08d57647695680824ad42 260 Pfam PF00392 Bacterial regulatory proteins, gntR family 61 120 2.8E-14 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS31135 8e662e9935e08d57647695680824ad42 260 SMART SM00895 130 255 1.5E-13 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS31135 8e662e9935e08d57647695680824ad42 260 SMART SM00345 62 120 1.7E-10 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS31135 8e662e9935e08d57647695680824ad42 260 Gene3D G3DSA:1.10.10.10 50 121 1.5E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31135 8e662e9935e08d57647695680824ad42 260 SUPERFAMILY SSF48008 127 259 1.36E-20 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS31135 8e662e9935e08d57647695680824ad42 260 Pfam PF07729 FCD domain 131 254 2.6E-18 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS31135 8e662e9935e08d57647695680824ad42 260 SUPERFAMILY SSF46785 54 124 3.26E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26130 0d9b67e3329dfbfe8fc147a81c07e7c3 587 PANTHER PTHR12526 190 248 1.3E-38 T 23-04-2016 DC74_RS26130 0d9b67e3329dfbfe8fc147a81c07e7c3 587 PANTHER PTHR12526 277 522 1.3E-38 T 23-04-2016 DC74_RS26130 0d9b67e3329dfbfe8fc147a81c07e7c3 587 Pfam PF11997 Domain of unknown function (DUF3492) 2 297 2.3E-31 T 23-04-2016 IPR022622 Domain of unknown function DUF3492 DC74_RS26130 0d9b67e3329dfbfe8fc147a81c07e7c3 587 Gene3D G3DSA:3.40.50.2000 321 495 4.3E-16 T 23-04-2016 DC74_RS26130 0d9b67e3329dfbfe8fc147a81c07e7c3 587 SUPERFAMILY SSF53756 2 48 1.57E-53 T 23-04-2016 DC74_RS26130 0d9b67e3329dfbfe8fc147a81c07e7c3 587 SUPERFAMILY SSF53756 204 514 1.57E-53 T 23-04-2016 DC74_RS26130 0d9b67e3329dfbfe8fc147a81c07e7c3 587 SUPERFAMILY SSF53756 79 96 1.57E-53 T 23-04-2016 DC74_RS26130 0d9b67e3329dfbfe8fc147a81c07e7c3 587 Pfam PF13692 Glycosyl transferases group 1 325 482 4.4E-21 T 23-04-2016 DC74_RS24950 e5e84ad15fa409cdc3029f5c26fb801b 440 ProSitePatterns PS00216 Sugar transport proteins signature 1. 103 119 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS24950 e5e84ad15fa409cdc3029f5c26fb801b 440 Gene3D G3DSA:1.20.1250.20 253 425 4.3E-9 T 23-04-2016 DC74_RS24950 e5e84ad15fa409cdc3029f5c26fb801b 440 PANTHER PTHR23501 28 434 5.9E-138 T 23-04-2016 DC74_RS24950 e5e84ad15fa409cdc3029f5c26fb801b 440 PANTHER PTHR23501:SF80 28 434 5.9E-138 T 23-04-2016 DC74_RS24950 e5e84ad15fa409cdc3029f5c26fb801b 440 Gene3D G3DSA:1.20.1250.20 37 228 2.4E-27 T 23-04-2016 DC74_RS24950 e5e84ad15fa409cdc3029f5c26fb801b 440 SUPERFAMILY SSF103473 32 426 5.62E-60 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS24950 e5e84ad15fa409cdc3029f5c26fb801b 440 Pfam PF07690 Major Facilitator Superfamily 54 360 7.1E-35 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS28270 3ff110cc3dda698d27317a15ec8aece7 246 PANTHER PTHR24220:SF111 11 230 6.9E-73 T 23-04-2016 DC74_RS28270 3ff110cc3dda698d27317a15ec8aece7 246 PANTHER PTHR24220 11 230 6.9E-73 T 23-04-2016 DC74_RS28270 3ff110cc3dda698d27317a15ec8aece7 246 SUPERFAMILY SSF52540 9 224 2.84E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28270 3ff110cc3dda698d27317a15ec8aece7 246 SMART SM00382 34 222 1.0E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS28270 3ff110cc3dda698d27317a15ec8aece7 246 Pfam PF00005 ABC transporter 25 174 6.4E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS28270 3ff110cc3dda698d27317a15ec8aece7 246 Gene3D G3DSA:3.40.50.300 10 228 9.5E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 SUPERFAMILY SSF51735 2 256 9.61E-81 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 Gene3D G3DSA:3.40.50.720 2 256 1.0E-84 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PANTHER PTHR24322 162 193 5.6E-49 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 255 7.0E-65 T 23-04-2016 DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 7.0E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 7.0E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 7.0E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 7.0E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 7.0E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 7.0E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PANTHER PTHR24322 9 146 5.6E-49 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PANTHER PTHR24322:SF328 162 193 5.6E-49 T 23-04-2016 DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PANTHER PTHR24322:SF328 9 146 5.6E-49 T 23-04-2016 DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.9E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.9E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37490 eae49444a8c28cd3da103942a5bf73b1 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.9E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS15210 8fec5d4151534672a805ce3cb1945d09 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 2.0E-35 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15210 8fec5d4151534672a805ce3cb1945d09 85 Gene3D G3DSA:2.40.50.100 20 82 1.5E-27 T 23-04-2016 DC74_RS15210 8fec5d4151534672a805ce3cb1945d09 85 Pfam PF01016 Ribosomal L27 protein 2 80 4.7E-35 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15210 8fec5d4151534672a805ce3cb1945d09 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 4.0E-35 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15210 8fec5d4151534672a805ce3cb1945d09 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 4.0E-35 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15210 8fec5d4151534672a805ce3cb1945d09 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 4.0E-35 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15210 8fec5d4151534672a805ce3cb1945d09 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 26.746 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15210 8fec5d4151534672a805ce3cb1945d09 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 5.0E-16 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15210 8fec5d4151534672a805ce3cb1945d09 85 PANTHER PTHR15893 1 85 4.6E-45 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15210 8fec5d4151534672a805ce3cb1945d09 85 SUPERFAMILY SSF110324 2 82 5.23E-31 T 23-04-2016 DC74_RS15210 8fec5d4151534672a805ce3cb1945d09 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 23-04-2016 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS07165 7afc04d1a7c13c845048f49ecc4e8b2b 346 Pfam PF14716 Helix-hairpin-helix domain 4 69 4.2E-13 T 23-04-2016 IPR010996 DNA polymerase beta-like, N-terminal domain DC74_RS07165 7afc04d1a7c13c845048f49ecc4e8b2b 346 SUPERFAMILY SSF89550 102 339 7.98E-50 T 23-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 DC74_RS07165 7afc04d1a7c13c845048f49ecc4e8b2b 346 Gene3D G3DSA:3.20.20.140 102 335 1.4E-47 T 23-04-2016 DC74_RS07165 7afc04d1a7c13c845048f49ecc4e8b2b 346 Pfam PF02811 PHP domain 104 191 2.1E-6 T 23-04-2016 IPR004013 PHP domain GO:0003824 DC74_RS07165 7afc04d1a7c13c845048f49ecc4e8b2b 346 SMART SM00481 103 182 4.0E-18 T 23-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 DC74_RS07165 7afc04d1a7c13c845048f49ecc4e8b2b 346 SUPERFAMILY SSF47802 3 82 2.62E-12 T 23-04-2016 IPR010996 DNA polymerase beta-like, N-terminal domain DC74_RS07165 7afc04d1a7c13c845048f49ecc4e8b2b 346 PANTHER PTHR36928 6 346 9.5E-100 T 23-04-2016 DC74_RS07165 7afc04d1a7c13c845048f49ecc4e8b2b 346 PIRSF PIRSF036978 1 339 3.5E-167 T 23-04-2016 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 DC74_RS07165 7afc04d1a7c13c845048f49ecc4e8b2b 346 Gene3D G3DSA:1.10.8.310 4 82 5.7E-10 T 23-04-2016 IPR027420 DNA polymerase beta, N-terminal domain DC74_RS24485 bc4a73f3a910bccecb0742bccce972dc 2191 Pfam PF13699 Domain of unknown function (DUF4157) 45 120 2.2E-26 T 23-04-2016 IPR025295 Domain of unknown function DUF4157 DC74_RS05015 7adfaa1b94d60dd4b2e55c709c277ee3 470 PIRSF PIRSF019251 1 466 8.4E-201 T 23-04-2016 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 DC74_RS05015 7adfaa1b94d60dd4b2e55c709c277ee3 470 SUPERFAMILY SSF47413 5 67 1.47E-15 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS05015 7adfaa1b94d60dd4b2e55c709c277ee3 470 PANTHER PTHR10245 7 101 3.9E-13 T 23-04-2016 DC74_RS05015 7adfaa1b94d60dd4b2e55c709c277ee3 470 Pfam PF06114 Domain of unknown function (DUF955) 198 304 2.4E-18 T 23-04-2016 IPR010359 HTH domain, IrrE-type DC74_RS05015 7adfaa1b94d60dd4b2e55c709c277ee3 470 Pfam PF13560 Helix-turn-helix domain 7 61 1.4E-13 T 23-04-2016 DC74_RS05015 7adfaa1b94d60dd4b2e55c709c277ee3 470 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 305 461 2.0E-71 T 23-04-2016 IPR018653 Domain of unknown function DUF2083,transcriptional regulator DC74_RS05015 7adfaa1b94d60dd4b2e55c709c277ee3 470 Gene3D G3DSA:1.10.260.40 4 73 2.3E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS05015 7adfaa1b94d60dd4b2e55c709c277ee3 470 SMART SM00530 9 64 5.4E-16 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS20225 0795252c9cd5eb02915767cc7cf0cca5 243 PANTHER PTHR30151:SF23 22 231 5.8E-59 T 23-04-2016 DC74_RS20225 0795252c9cd5eb02915767cc7cf0cca5 243 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 222 3.2E-18 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS20225 0795252c9cd5eb02915767cc7cf0cca5 243 PANTHER PTHR30151 22 231 5.8E-59 T 23-04-2016 DC74_RS20225 0795252c9cd5eb02915767cc7cf0cca5 243 SUPERFAMILY SSF161098 26 209 3.53E-34 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS20225 0795252c9cd5eb02915767cc7cf0cca5 243 Gene3D G3DSA:1.10.3720.10 21 209 7.7E-27 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38270 f11312c6ad53304a895793aa824feb3c 104 SUPERFAMILY SSF55729 59 93 2.02E-5 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS38270 f11312c6ad53304a895793aa824feb3c 104 Gene3D G3DSA:3.40.630.30 60 99 4.1E-9 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS35935 7ec517b47be2e939b0b2fc8b6b452c8c 433 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 11 429 5.4E-129 T 23-04-2016 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 KEGG: 00480+1.11.1.- DC74_RS35935 7ec517b47be2e939b0b2fc8b6b452c8c 433 PANTHER PTHR30521:SF4 63 432 3.2E-120 T 23-04-2016 DC74_RS35935 7ec517b47be2e939b0b2fc8b6b452c8c 433 SUPERFAMILY SSF54909 78 418 4.47E-84 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS35935 7ec517b47be2e939b0b2fc8b6b452c8c 433 PANTHER PTHR30521 63 432 3.2E-120 T 23-04-2016 DC74_RS35935 7ec517b47be2e939b0b2fc8b6b452c8c 433 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 83 418 2.0E-85 T 23-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- DC74_RS35935 7ec517b47be2e939b0b2fc8b6b452c8c 433 Pfam PF04261 Dyp-type peroxidase family 83 418 3.4E-94 T 23-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- DC74_RS30125 ab4d891581ab9730f70013a18c7c641c 344 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 8 334 1.4E-78 T 23-04-2016 IPR002729 CRISPR-associated protein Cas1 DC74_RS30125 ab4d891581ab9730f70013a18c7c641c 344 TIGRFAM TIGR03640 cas1_DVULG: CRISPR-associated endonuclease Cas1, subtype I-C/DVULG 5 342 5.5E-132 T 23-04-2016 IPR019856 CRISPR-associated protein Cas1, DVULG subtype DC74_RS30125 ab4d891581ab9730f70013a18c7c641c 344 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 8 341 22.916 T 23-04-2016 IPR002729 CRISPR-associated protein Cas1 DC74_RS30125 ab4d891581ab9730f70013a18c7c641c 344 Pfam PF01867 CRISPR associated protein Cas1 9 298 3.6E-97 T 23-04-2016 IPR002729 CRISPR-associated protein Cas1 DC74_RS30125 ab4d891581ab9730f70013a18c7c641c 344 PANTHER PTHR34353:SF2 8 344 6.4E-91 T 23-04-2016 DC74_RS30125 ab4d891581ab9730f70013a18c7c641c 344 PANTHER PTHR34353 8 344 6.4E-91 T 23-04-2016 DC74_RS09185 ececb9bc4aa7239dbbacf97a7036296d 376 SMART SM00116 285 333 0.38 T 23-04-2016 IPR000644 CBS domain DC74_RS09185 ececb9bc4aa7239dbbacf97a7036296d 376 SMART SM00116 225 273 0.91 T 23-04-2016 IPR000644 CBS domain DC74_RS09185 ececb9bc4aa7239dbbacf97a7036296d 376 Pfam PF01595 Domain of unknown function DUF21 8 199 1.3E-43 T 23-04-2016 IPR002550 Domain of unknown function DUF21 DC74_RS09185 ececb9bc4aa7239dbbacf97a7036296d 376 Gene3D G3DSA:3.10.580.10 226 333 2.2E-15 T 23-04-2016 DC74_RS09185 ececb9bc4aa7239dbbacf97a7036296d 376 SUPERFAMILY SSF54631 207 344 2.53E-22 T 23-04-2016 DC74_RS09185 ececb9bc4aa7239dbbacf97a7036296d 376 PANTHER PTHR22777:SF18 5 357 8.2E-121 T 23-04-2016 DC74_RS09185 ececb9bc4aa7239dbbacf97a7036296d 376 Pfam PF00571 CBS domain 284 333 1.5E-4 T 23-04-2016 IPR000644 CBS domain DC74_RS09185 ececb9bc4aa7239dbbacf97a7036296d 376 Pfam PF00571 CBS domain 226 270 0.0023 T 23-04-2016 IPR000644 CBS domain DC74_RS09185 ececb9bc4aa7239dbbacf97a7036296d 376 PANTHER PTHR22777 5 357 8.2E-121 T 23-04-2016 DC74_RS10680 ad7dd48d935b8cd76a83b0d86f390ec8 480 PANTHER PTHR11895 1 478 2.9E-127 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS10680 ad7dd48d935b8cd76a83b0d86f390ec8 480 SUPERFAMILY SSF75304 2 469 7.06E-126 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS10680 ad7dd48d935b8cd76a83b0d86f390ec8 480 Pfam PF01425 Amidase 25 459 2.3E-107 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS10680 ad7dd48d935b8cd76a83b0d86f390ec8 480 Gene3D G3DSA:3.90.1300.10 2 479 3.6E-125 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS10680 ad7dd48d935b8cd76a83b0d86f390ec8 480 ProSitePatterns PS00571 Amidases signature. 157 188 - T 23-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS13335 f1f9b2beb7c4875c76c0bec82de8b998 303 SUPERFAMILY SSF51621 40 302 8.64E-101 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS13335 f1f9b2beb7c4875c76c0bec82de8b998 303 PANTHER PTHR20881 39 302 7.7E-138 T 23-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 DC74_RS13335 f1f9b2beb7c4875c76c0bec82de8b998 303 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 49 303 2.3E-93 T 23-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 DC74_RS13335 f1f9b2beb7c4875c76c0bec82de8b998 303 Pfam PF02548 Ketopantoate hydroxymethyltransferase 40 297 2.7E-106 T 23-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 DC74_RS13335 f1f9b2beb7c4875c76c0bec82de8b998 303 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 41 302 42.528 T 23-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 DC74_RS13335 f1f9b2beb7c4875c76c0bec82de8b998 303 Gene3D G3DSA:3.20.20.60 39 303 1.7E-110 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS13335 f1f9b2beb7c4875c76c0bec82de8b998 303 PIRSF PIRSF000388 35 303 2.8E-107 T 23-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 DC74_RS38475 d7014b55007c4e23fec372c7ab3d5a79 319 Gene3D G3DSA:1.10.3720.10 93 302 4.7E-16 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38475 d7014b55007c4e23fec372c7ab3d5a79 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 311 1.4E-28 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38475 d7014b55007c4e23fec372c7ab3d5a79 319 PANTHER PTHR30465 1 312 3.3E-86 T 23-04-2016 DC74_RS38475 d7014b55007c4e23fec372c7ab3d5a79 319 PANTHER PTHR30465:SF0 1 312 3.3E-86 T 23-04-2016 DC74_RS38475 d7014b55007c4e23fec372c7ab3d5a79 319 SUPERFAMILY SSF161098 93 296 7.59E-17 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS11110 b110ac4bf3713232c5d12e1de6834776 292 Gene3D G3DSA:2.60.200.30 146 256 3.8E-37 T 23-04-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS11110 b110ac4bf3713232c5d12e1de6834776 292 Hamap MF_00361 NAD kinase [nadK]. 2 282 28.696 T 23-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS11110 b110ac4bf3713232c5d12e1de6834776 292 Pfam PF01513 ATP-NAD kinase 46 266 1.2E-57 T 23-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS11110 b110ac4bf3713232c5d12e1de6834776 292 Gene3D G3DSA:3.40.50.10330 1 145 5.0E-32 T 23-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS11110 b110ac4bf3713232c5d12e1de6834776 292 SUPERFAMILY SSF111331 1 288 2.22E-78 T 23-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain DC74_RS11110 b110ac4bf3713232c5d12e1de6834776 292 PANTHER PTHR20275 1 280 2.2E-73 T 23-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS24525 d84d0f5b246c107c512097d405c1785b 392 Gene3D G3DSA:3.30.1490.20 22 85 2.5E-17 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS24525 d84d0f5b246c107c512097d405c1785b 392 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 250 274 - T 23-04-2016 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS24525 d84d0f5b246c107c512097d405c1785b 392 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 389 3.1E-122 T 23-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 DC74_RS24525 d84d0f5b246c107c512097d405c1785b 392 Pfam PF00549 CoA-ligase 257 376 3.7E-14 T 23-04-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS24525 d84d0f5b246c107c512097d405c1785b 392 PIRSF PIRSF001554 1 392 9.0E-136 T 23-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 DC74_RS24525 d84d0f5b246c107c512097d405c1785b 392 SUPERFAMILY SSF56059 3 227 7.26E-62 T 23-04-2016 DC74_RS24525 d84d0f5b246c107c512097d405c1785b 392 PANTHER PTHR11815 2 392 3.7E-164 T 23-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 DC74_RS24525 d84d0f5b246c107c512097d405c1785b 392 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 390 40.37 T 23-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 DC74_RS24525 d84d0f5b246c107c512097d405c1785b 392 SUPERFAMILY SSF52210 232 389 2.62E-42 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS24525 d84d0f5b246c107c512097d405c1785b 392 Pfam PF08442 ATP-grasp domain 2 195 7.6E-67 T 23-04-2016 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS24525 d84d0f5b246c107c512097d405c1785b 392 Gene3D G3DSA:3.40.50.261 233 389 5.2E-53 T 23-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS24525 d84d0f5b246c107c512097d405c1785b 392 Gene3D G3DSA:3.30.470.20 86 229 2.1E-49 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS25365 31c615872bb05a20dfdb627f0456cffd 255 SUPERFAMILY SSF46785 3 72 1.23E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25365 31c615872bb05a20dfdb627f0456cffd 255 SUPERFAMILY SSF55781 57 244 4.84E-49 T 23-04-2016 IPR029016 GAF domain-like DC74_RS25365 31c615872bb05a20dfdb627f0456cffd 255 Gene3D G3DSA:3.30.450.40 71 247 4.8E-58 T 23-04-2016 IPR029016 GAF domain-like DC74_RS25365 31c615872bb05a20dfdb627f0456cffd 255 Gene3D G3DSA:1.10.10.10 2 70 7.9E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25365 31c615872bb05a20dfdb627f0456cffd 255 Pfam PF09339 IclR helix-turn-helix domain 4 53 1.7E-14 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS25365 31c615872bb05a20dfdb627f0456cffd 255 PANTHER PTHR30136:SF2 3 255 2.0E-99 T 23-04-2016 DC74_RS25365 31c615872bb05a20dfdb627f0456cffd 255 PANTHER PTHR30136 3 255 2.0E-99 T 23-04-2016 DC74_RS25365 31c615872bb05a20dfdb627f0456cffd 255 SMART SM00346 2 89 3.9E-25 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS25365 31c615872bb05a20dfdb627f0456cffd 255 Pfam PF01614 Bacterial transcriptional regulator 117 241 1.0E-30 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS28005 5a4cbcc885485800c11e15783242fcac 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 55 18.926 T 23-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 DC74_RS28005 5a4cbcc885485800c11e15783242fcac 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 2.6E-25 T 23-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 DC74_RS28005 5a4cbcc885485800c11e15783242fcac 57 SUPERFAMILY SSF57829 2 55 1.28E-20 T 23-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 DC74_RS28005 5a4cbcc885485800c11e15783242fcac 57 Pfam PF01783 Ribosomal L32p protein family 2 56 4.8E-25 T 23-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 DC74_RS39510 03a88609b39f076a012c8d8b0c154103 191 PANTHER PTHR30055:SF19 4 187 4.1E-60 T 23-04-2016 DC74_RS39510 03a88609b39f076a012c8d8b0c154103 191 SUPERFAMILY SSF46689 7 87 4.79E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39510 03a88609b39f076a012c8d8b0c154103 191 SUPERFAMILY SSF48498 86 189 3.15E-13 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS39510 03a88609b39f076a012c8d8b0c154103 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 6.2E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39510 03a88609b39f076a012c8d8b0c154103 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.6E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39510 03a88609b39f076a012c8d8b0c154103 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.6E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39510 03a88609b39f076a012c8d8b0c154103 191 PANTHER PTHR30055 4 187 4.1E-60 T 23-04-2016 DC74_RS39510 03a88609b39f076a012c8d8b0c154103 191 Gene3D G3DSA:1.10.357.10 9 191 1.4E-41 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS40275 b981f5e89e2950f47b18590a72fdacea 235 PANTHER PTHR11751 122 146 1.5E-15 T 23-04-2016 DC74_RS40275 b981f5e89e2950f47b18590a72fdacea 235 PANTHER PTHR11751 5 71 1.5E-15 T 23-04-2016 DC74_RS40275 b981f5e89e2950f47b18590a72fdacea 235 SMART SM00866 96 229 3.9E-4 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS40275 b981f5e89e2950f47b18590a72fdacea 235 Pfam PF07702 UTRA domain 111 227 3.9E-12 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS40275 b981f5e89e2950f47b18590a72fdacea 235 SUPERFAMILY SSF64288 57 233 1.57E-18 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS40275 b981f5e89e2950f47b18590a72fdacea 235 SMART SM00345 10 69 4.6E-20 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40275 b981f5e89e2950f47b18590a72fdacea 235 Gene3D G3DSA:1.10.10.10 4 64 6.8E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS40275 b981f5e89e2950f47b18590a72fdacea 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 8.9E-19 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40275 b981f5e89e2950f47b18590a72fdacea 235 SUPERFAMILY SSF46785 3 73 2.04E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS40275 b981f5e89e2950f47b18590a72fdacea 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 1.4E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40275 b981f5e89e2950f47b18590a72fdacea 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 1.4E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS40275 b981f5e89e2950f47b18590a72fdacea 235 Gene3D G3DSA:3.40.1410.10 65 233 1.3E-14 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS07740 4028020874585f8612fa5e89e4676ca9 230 PANTHER PTHR31126:SF21 1 160 1.9E-24 T 23-04-2016 DC74_RS07740 4028020874585f8612fa5e89e4676ca9 230 PANTHER PTHR31126:SF21 183 228 1.9E-24 T 23-04-2016 DC74_RS07740 4028020874585f8612fa5e89e4676ca9 230 PANTHER PTHR31126 183 228 1.9E-24 T 23-04-2016 DC74_RS07740 4028020874585f8612fa5e89e4676ca9 230 SUPERFAMILY SSF52799 1 228 3.91E-31 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS07740 4028020874585f8612fa5e89e4676ca9 230 Gene3D G3DSA:3.90.190.10 2 156 2.1E-13 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS07740 4028020874585f8612fa5e89e4676ca9 230 Pfam PF13350 Tyrosine phosphatase family 1 228 1.4E-38 T 23-04-2016 IPR026893 Tyrosine/serine-protein phosphatase IphP-type DC74_RS07740 4028020874585f8612fa5e89e4676ca9 230 PANTHER PTHR31126 1 160 1.9E-24 T 23-04-2016 DC74_RS20170 fa0d032e2dfd82ef627639bbd81f6121 387 PANTHER PTHR35863 10 381 3.7E-97 T 23-04-2016 DC74_RS20170 fa0d032e2dfd82ef627639bbd81f6121 387 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 28 340 1.9E-51 T 23-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 DC74_RS20170 fa0d032e2dfd82ef627639bbd81f6121 387 SUPERFAMILY SSF111342 17 307 8.11E-82 T 23-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 DC74_RS20170 fa0d032e2dfd82ef627639bbd81f6121 387 PANTHER PTHR35863:SF1 10 381 3.7E-97 T 23-04-2016 DC74_RS20170 fa0d032e2dfd82ef627639bbd81f6121 387 Gene3D G3DSA:3.30.2110.10 24 204 5.4E-58 T 23-04-2016 DC74_RS20170 fa0d032e2dfd82ef627639bbd81f6121 387 Pfam PF01888 CbiD 21 289 5.4E-89 T 23-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 DC74_RS20170 fa0d032e2dfd82ef627639bbd81f6121 387 PIRSF PIRSF026782 17 384 3.7E-124 T 23-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 DC74_RS20170 fa0d032e2dfd82ef627639bbd81f6121 387 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 21 380 27.897 T 23-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 DC74_RS24810 f558dae53883cfce086090c2a9cf2dbf 245 SUPERFAMILY SSF88659 132 185 9.72E-10 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS24810 f558dae53883cfce086090c2a9cf2dbf 245 Gene3D G3DSA:1.10.1740.10 16 118 5.1E-26 T 23-04-2016 DC74_RS24810 f558dae53883cfce086090c2a9cf2dbf 245 Pfam PF04542 Sigma-70 region 2 32 98 2.4E-15 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS24810 f558dae53883cfce086090c2a9cf2dbf 245 SUPERFAMILY SSF88946 11 115 2.88E-24 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS24810 f558dae53883cfce086090c2a9cf2dbf 245 Pfam PF08281 Sigma-70, region 4 133 181 8.6E-11 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS24810 f558dae53883cfce086090c2a9cf2dbf 245 PANTHER PTHR30173 2 188 8.3E-72 T 23-04-2016 DC74_RS24810 f558dae53883cfce086090c2a9cf2dbf 245 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 184 1.9E-16 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS24810 f558dae53883cfce086090c2a9cf2dbf 245 Gene3D G3DSA:1.10.10.10 133 187 2.0E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24810 f558dae53883cfce086090c2a9cf2dbf 245 PANTHER PTHR30173:SF3 2 188 8.3E-72 T 23-04-2016 DC74_RS07680 58f8b219ef542a761c502bc01cb29f94 331 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 5.2E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS07680 58f8b219ef542a761c502bc01cb29f94 331 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 5.2E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS07680 58f8b219ef542a761c502bc01cb29f94 331 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 5.2E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS07680 58f8b219ef542a761c502bc01cb29f94 331 SUPERFAMILY SSF46785 3 115 4.54E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07680 58f8b219ef542a761c502bc01cb29f94 331 PANTHER PTHR30346 1 312 1.1E-89 T 23-04-2016 DC74_RS07680 58f8b219ef542a761c502bc01cb29f94 331 PANTHER PTHR30346:SF6 1 312 1.1E-89 T 23-04-2016 DC74_RS07680 58f8b219ef542a761c502bc01cb29f94 331 Gene3D G3DSA:1.10.10.10 3 87 6.5E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07680 58f8b219ef542a761c502bc01cb29f94 331 Pfam PF03466 LysR substrate binding domain 94 295 2.4E-23 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS07680 58f8b219ef542a761c502bc01cb29f94 331 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 3.1E-18 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS07680 58f8b219ef542a761c502bc01cb29f94 331 Gene3D G3DSA:3.40.190.10 97 182 1.7E-8 T 23-04-2016 DC74_RS07680 58f8b219ef542a761c502bc01cb29f94 331 SUPERFAMILY SSF53850 95 298 3.57E-23 T 23-04-2016 DC74_RS07680 58f8b219ef542a761c502bc01cb29f94 331 Gene3D G3DSA:3.40.190.10 183 268 1.2E-15 T 23-04-2016 DC74_RS29530 2eac4da60a6ffa666ae223861d071900 161 SUPERFAMILY SSF82199 23 120 1.44E-15 T 23-04-2016 DC74_RS29530 2eac4da60a6ffa666ae223861d071900 161 Gene3D G3DSA:2.170.270.10 31 119 1.8E-12 T 23-04-2016 DC74_RS29530 2eac4da60a6ffa666ae223861d071900 161 Pfam PF00856 SET domain 57 104 4.7E-7 T 23-04-2016 IPR001214 SET domain GO:0005515 DC74_RS29530 2eac4da60a6ffa666ae223861d071900 161 PANTHER PTHR12350 36 155 7.4E-32 T 23-04-2016 DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 PANTHER PTHR11695:SF269 322 381 1.8E-89 T 23-04-2016 DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 PANTHER PTHR11695:SF269 13 49 1.8E-89 T 23-04-2016 DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 PANTHER PTHR11695:SF269 80 306 1.8E-89 T 23-04-2016 DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 SUPERFAMILY SSF55347 561 689 1.31E-9 T 23-04-2016 DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 Gene3D G3DSA:3.40.50.720 176 290 1.4E-26 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 Gene3D G3DSA:3.90.180.10 9 54 7.1E-15 T 23-04-2016 IPR011032 GroES-like DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 Gene3D G3DSA:3.90.180.10 88 175 7.1E-15 T 23-04-2016 IPR011032 GroES-like DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 SUPERFAMILY SSF50129 87 180 5.07E-17 T 23-04-2016 IPR011032 GroES-like DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 SUPERFAMILY SSF50129 7 55 5.07E-17 T 23-04-2016 IPR011032 GroES-like DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 SMART SM00829 50 367 0.01 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 Gene3D G3DSA:3.40.50.720 403 532 1.1E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 406 526 2.0E-21 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 PANTHER PTHR11695 322 381 1.8E-89 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 PANTHER PTHR11695 13 49 1.8E-89 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 PANTHER PTHR11695 80 306 1.8E-89 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 Gene3D G3DSA:3.30.360.10 533 723 2.3E-23 T 23-04-2016 DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 Pfam PF00107 Zinc-binding dehydrogenase 182 296 8.7E-16 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 SUPERFAMILY SSF51735 150 299 1.04E-27 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS05460 26252655fc8a11095c2f70a6562d2aca 725 SUPERFAMILY SSF51735 395 566 1.49E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16790 44fac020bbceb28ce76beab876850cd0 727 Gene3D G3DSA:3.40.50.10320 153 276 2.1E-15 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS16790 44fac020bbceb28ce76beab876850cd0 727 Gene3D G3DSA:3.40.50.10320 53 99 2.1E-15 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS16790 44fac020bbceb28ce76beab876850cd0 727 SUPERFAMILY SSF89372 478 706 9.81E-10 T 23-04-2016 DC74_RS16790 44fac020bbceb28ce76beab876850cd0 727 Pfam PF02585 GlcNAc-PI de-N-acetylase 53 273 1.8E-15 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS16790 44fac020bbceb28ce76beab876850cd0 727 SUPERFAMILY SSF102588 178 279 1.31E-13 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS16790 44fac020bbceb28ce76beab876850cd0 727 SUPERFAMILY SSF102588 52 127 1.31E-13 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS28915 82c49d0fb88fc82d9546c2e835edeaa0 580 Pfam PF06276 Ferric iron reductase FhuF-like transporter 398 558 1.7E-38 T 23-04-2016 IPR022770 Ferric iron reductase FhuF domain DC74_RS28915 82c49d0fb88fc82d9546c2e835edeaa0 580 PANTHER PTHR34384:SF5 1 578 6.6E-177 T 23-04-2016 DC74_RS28915 82c49d0fb88fc82d9546c2e835edeaa0 580 PANTHER PTHR34384 1 578 6.6E-177 T 23-04-2016 DC74_RS28915 82c49d0fb88fc82d9546c2e835edeaa0 580 Pfam PF04183 IucA / IucC family 125 376 3.9E-75 T 23-04-2016 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 DC74_RS29715 c162c5c9d2af200a0dfd8e9e4081c9a9 477 Gene3D G3DSA:3.40.190.10 185 385 2.3E-25 T 23-04-2016 DC74_RS29715 c162c5c9d2af200a0dfd8e9e4081c9a9 477 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 25 473 2.7E-173 T 23-04-2016 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding DC74_RS29715 c162c5c9d2af200a0dfd8e9e4081c9a9 477 Pfam PF01547 Bacterial extracellular solute-binding protein 77 377 4.4E-20 T 23-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 DC74_RS29715 c162c5c9d2af200a0dfd8e9e4081c9a9 477 SUPERFAMILY SSF53850 61 467 8.45E-44 T 23-04-2016 DC74_RS29715 c162c5c9d2af200a0dfd8e9e4081c9a9 477 PANTHER PTHR30061 1 467 9.9E-35 T 23-04-2016 DC74_RS28475 f20ac10430be20ebdc076b87a4d5a6e2 404 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 198 307 2.1E-24 T 23-04-2016 IPR021368 Type VII secretion system protein EccE DC74_RS28475 f20ac10430be20ebdc076b87a4d5a6e2 404 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 10 404 2.2E-57 T 23-04-2016 IPR021368 Type VII secretion system protein EccE DC74_RS25760 e6c653a04d5117b066cb85e50db33e73 142 Pfam PF00293 NUDIX domain 6 115 3.1E-17 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS25760 e6c653a04d5117b066cb85e50db33e73 142 Gene3D G3DSA:3.90.79.10 3 129 2.3E-29 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS25760 e6c653a04d5117b066cb85e50db33e73 142 PANTHER PTHR22769 1 128 4.3E-22 T 23-04-2016 DC74_RS25760 e6c653a04d5117b066cb85e50db33e73 142 PANTHER PTHR22769:SF35 1 128 4.3E-22 T 23-04-2016 DC74_RS25760 e6c653a04d5117b066cb85e50db33e73 142 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS25760 e6c653a04d5117b066cb85e50db33e73 142 SUPERFAMILY SSF55811 3 129 3.79E-29 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS25760 e6c653a04d5117b066cb85e50db33e73 142 PRINTS PR00502 NUDIX hydrolase family signature 33 47 7.7E-10 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS25760 e6c653a04d5117b066cb85e50db33e73 142 PRINTS PR00502 NUDIX hydrolase family signature 47 62 7.7E-10 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS25420 1b2a8bea5245a9e18021df4e7a915a31 315 PANTHER PTHR35007:SF1 27 315 6.0E-71 T 23-04-2016 DC74_RS25420 1b2a8bea5245a9e18021df4e7a915a31 315 PANTHER PTHR35007 27 315 6.0E-71 T 23-04-2016 DC74_RS25420 1b2a8bea5245a9e18021df4e7a915a31 315 Pfam PF00482 Type II secretion system (T2SS), protein F 148 271 2.0E-18 T 23-04-2016 IPR018076 Type II secretion system F domain DC74_RS08370 30d3d02c731d9392de9c19d31561d509 231 SUPERFAMILY SSF50475 36 231 7.03E-46 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS08370 30d3d02c731d9392de9c19d31561d509 231 Gene3D G3DSA:2.30.110.10 39 231 1.0E-57 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS08370 30d3d02c731d9392de9c19d31561d509 231 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 191 231 1.7E-9 T 23-04-2016 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS08370 30d3d02c731d9392de9c19d31561d509 231 PIRSF PIRSF000190 30 231 5.3E-54 T 23-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS08370 30d3d02c731d9392de9c19d31561d509 231 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 55 132 4.7E-19 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS08370 30d3d02c731d9392de9c19d31561d509 231 PANTHER PTHR10851 41 231 1.4E-57 T 23-04-2016 DC74_RS03120 db7956fbcf075f535baf1be886f4943b 337 Pfam PF00107 Zinc-binding dehydrogenase 163 284 1.8E-20 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS03120 db7956fbcf075f535baf1be886f4943b 337 Gene3D G3DSA:3.40.50.720 162 274 4.7E-22 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03120 db7956fbcf075f535baf1be886f4943b 337 SMART SM00829 10 334 4.3E-10 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS03120 db7956fbcf075f535baf1be886f4943b 337 SUPERFAMILY SSF51735 118 297 9.41E-29 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03120 db7956fbcf075f535baf1be886f4943b 337 PANTHER PTHR11695 15 337 1.3E-67 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS03120 db7956fbcf075f535baf1be886f4943b 337 SUPERFAMILY SSF50129 1 138 6.39E-32 T 23-04-2016 IPR011032 GroES-like DC74_RS03120 db7956fbcf075f535baf1be886f4943b 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 86 7.5E-6 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS03120 db7956fbcf075f535baf1be886f4943b 337 Gene3D G3DSA:3.90.180.10 1 161 8.7E-35 T 23-04-2016 IPR011032 GroES-like DC74_RS31750 797df730d1a8e14368e65ab7757d490d 215 Pfam PF02666 Phosphatidylserine decarboxylase 56 209 1.2E-30 T 23-04-2016 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 DC74_RS31750 797df730d1a8e14368e65ab7757d490d 215 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 14 215 32.519 T 23-04-2016 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 DC74_RS31750 797df730d1a8e14368e65ab7757d490d 215 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 43 212 4.0E-52 T 23-04-2016 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 DC74_RS31750 797df730d1a8e14368e65ab7757d490d 215 PANTHER PTHR35809 7 214 5.7E-67 T 23-04-2016 DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 PANTHER PTHR24322 155 186 9.5E-53 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 PANTHER PTHR24322 14 139 9.5E-53 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 SUPERFAMILY SSF51735 8 244 8.98E-64 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 Gene3D G3DSA:3.40.50.720 10 252 1.0E-67 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.6E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.6E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.6E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 Pfam PF00106 short chain dehydrogenase 13 195 1.8E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 8.4E-26 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 8.4E-26 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 8.4E-26 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 8.4E-26 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39695 3f973080f7a276b30363cf89f44ec84d 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 8.4E-26 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 SUPERFAMILY SSF52980 1366 1469 1.13E-8 T 23-04-2016 IPR011335 Restriction endonuclease type II-like DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 Pfam PF13087 AAA domain 1150 1321 2.0E-16 T 23-04-2016 DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 PANTHER PTHR10887:SF340 99 114 3.0E-51 T 23-04-2016 DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 PANTHER PTHR10887:SF340 1144 1344 3.0E-51 T 23-04-2016 DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 PANTHER PTHR10887:SF340 369 452 3.0E-51 T 23-04-2016 DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 PANTHER PTHR10887:SF340 958 1117 3.0E-51 T 23-04-2016 DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 SUPERFAMILY SSF52540 372 495 1.8E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 SUPERFAMILY SSF52540 1047 1321 1.8E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 Pfam PF13245 Part of AAA domain 386 450 4.6E-9 T 23-04-2016 DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 Gene3D G3DSA:3.40.50.300 1168 1328 3.5E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 PANTHER PTHR10887 99 114 3.0E-51 T 23-04-2016 DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 PANTHER PTHR10887 1144 1344 3.0E-51 T 23-04-2016 DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 PANTHER PTHR10887 369 452 3.0E-51 T 23-04-2016 DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 PANTHER PTHR10887 958 1117 3.0E-51 T 23-04-2016 DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 Gene3D G3DSA:3.40.50.300 365 478 1.8E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29585 04d73a6a2f000ea6e2afe11e8b8bcf37 1531 Gene3D G3DSA:3.40.50.300 1068 1167 1.8E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS40195 d612eff0d9259d30d30a10af8b9e569e 346 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 200 277 1.5E-20 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS40195 d612eff0d9259d30d30a10af8b9e569e 346 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 283 344 7.5E-15 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS40195 d612eff0d9259d30d30a10af8b9e569e 346 Gene3D G3DSA:2.80.10.50 200 340 1.6E-39 T 23-04-2016 DC74_RS40195 d612eff0d9259d30d30a10af8b9e569e 346 PANTHER PTHR23115 1 188 1.8E-35 T 23-04-2016 DC74_RS40195 d612eff0d9259d30d30a10af8b9e569e 346 Pfam PF00009 Elongation factor Tu GTP binding domain 15 187 2.1E-19 T 23-04-2016 DC74_RS40195 d612eff0d9259d30d30a10af8b9e569e 346 PANTHER PTHR23115:SF112 1 188 1.8E-35 T 23-04-2016 DC74_RS40195 d612eff0d9259d30d30a10af8b9e569e 346 SMART SM00458 196 339 4.5E-12 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS40195 d612eff0d9259d30d30a10af8b9e569e 346 SUPERFAMILY SSF52540 10 163 1.15E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS40195 d612eff0d9259d30d30a10af8b9e569e 346 SUPERFAMILY SSF50370 199 340 8.78E-42 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS40195 d612eff0d9259d30d30a10af8b9e569e 346 Gene3D G3DSA:3.40.50.300 9 165 3.1E-25 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS03625 e08f0a08e05a6535e51862fa59be6d4b 173 Gene3D G3DSA:3.40.50.1820 7 141 2.8E-24 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS03625 e08f0a08e05a6535e51862fa59be6d4b 173 Pfam PF12697 Alpha/beta hydrolase family 10 143 3.3E-12 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS03625 e08f0a08e05a6535e51862fa59be6d4b 173 PANTHER PTHR10992 73 153 2.6E-16 T 23-04-2016 DC74_RS03625 e08f0a08e05a6535e51862fa59be6d4b 173 PANTHER PTHR10992 7 52 2.6E-16 T 23-04-2016 DC74_RS03625 e08f0a08e05a6535e51862fa59be6d4b 173 SUPERFAMILY SSF53474 6 151 4.93E-23 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02300 7e0c66b61f0260288a131b20a523b8c9 187 SUPERFAMILY SSF46689 27 72 3.19E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02300 7e0c66b61f0260288a131b20a523b8c9 187 Gene3D G3DSA:1.10.10.60 11 57 2.1E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02300 7e0c66b61f0260288a131b20a523b8c9 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 66 1.6E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS02300 7e0c66b61f0260288a131b20a523b8c9 187 Gene3D G3DSA:1.10.357.10 65 186 3.8E-23 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS02300 7e0c66b61f0260288a131b20a523b8c9 187 PANTHER PTHR30055 4 179 1.7E-31 T 23-04-2016 DC74_RS02300 7e0c66b61f0260288a131b20a523b8c9 187 SUPERFAMILY SSF48498 79 185 1.36E-13 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS02300 7e0c66b61f0260288a131b20a523b8c9 187 Pfam PF16859 Bacterial transcriptional repressor C-terminal 79 182 6.9E-20 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS02300 7e0c66b61f0260288a131b20a523b8c9 187 PANTHER PTHR30055:SF67 4 179 1.7E-31 T 23-04-2016 DC74_RS30345 9f3acc7acab26005b393fac95ac47afc 423 Pfam PF00145 C-5 cytosine-specific DNA methylase 2 83 3.2E-9 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS30345 9f3acc7acab26005b393fac95ac47afc 423 Pfam PF00145 C-5 cytosine-specific DNA methylase 359 407 8.0E-7 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS30345 9f3acc7acab26005b393fac95ac47afc 423 Pfam PF00145 C-5 cytosine-specific DNA methylase 111 190 8.1E-8 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS30345 9f3acc7acab26005b393fac95ac47afc 423 SUPERFAMILY SSF53335 2 82 8.13E-48 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS30345 9f3acc7acab26005b393fac95ac47afc 423 SUPERFAMILY SSF53335 110 240 8.13E-48 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS30345 9f3acc7acab26005b393fac95ac47afc 423 SUPERFAMILY SSF53335 361 406 8.13E-48 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS30345 9f3acc7acab26005b393fac95ac47afc 423 PANTHER PTHR10629 110 406 1.1E-35 T 23-04-2016 DC74_RS30345 9f3acc7acab26005b393fac95ac47afc 423 PANTHER PTHR10629 2 87 1.1E-35 T 23-04-2016 DC74_RS30345 9f3acc7acab26005b393fac95ac47afc 423 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 1 16 3.7E-9 T 23-04-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DC74_RS30345 9f3acc7acab26005b393fac95ac47afc 423 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 172 185 3.7E-9 T 23-04-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DC74_RS30345 9f3acc7acab26005b393fac95ac47afc 423 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 131 145 3.7E-9 T 23-04-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DC74_RS30345 9f3acc7acab26005b393fac95ac47afc 423 Gene3D G3DSA:3.40.50.150 2 224 4.4E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS02055 6a7c468e2f551d17cbced42665fbdc9f 136 Gene3D G3DSA:1.10.10.10 2 82 8.3E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02055 6a7c468e2f551d17cbced42665fbdc9f 136 SUPERFAMILY SSF46785 3 134 8.17E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02055 6a7c468e2f551d17cbced42665fbdc9f 136 PANTHER PTHR33202:SF7 1 136 2.7E-42 T 23-04-2016 DC74_RS02055 6a7c468e2f551d17cbced42665fbdc9f 136 Pfam PF01475 Ferric uptake regulator family 11 104 5.0E-25 T 23-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 DC74_RS02055 6a7c468e2f551d17cbced42665fbdc9f 136 PANTHER PTHR33202 1 136 2.7E-42 T 23-04-2016 DC74_RS26645 f573fefbc4de4496c575d36e3870fb5e 320 SMART SM00829 13 318 2.9E-12 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS26645 f573fefbc4de4496c575d36e3870fb5e 320 SUPERFAMILY SSF50129 6 154 4.4E-30 T 23-04-2016 IPR011032 GroES-like DC74_RS26645 f573fefbc4de4496c575d36e3870fb5e 320 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 78 2.1E-4 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS26645 f573fefbc4de4496c575d36e3870fb5e 320 SUPERFAMILY SSF51735 129 292 5.62E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26645 f573fefbc4de4496c575d36e3870fb5e 320 Pfam PF00107 Zinc-binding dehydrogenase 165 283 7.2E-17 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS26645 f573fefbc4de4496c575d36e3870fb5e 320 Gene3D G3DSA:3.40.50.720 160 267 1.8E-18 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26645 f573fefbc4de4496c575d36e3870fb5e 320 PANTHER PTHR11695:SF605 18 320 4.3E-90 T 23-04-2016 DC74_RS26645 f573fefbc4de4496c575d36e3870fb5e 320 Gene3D G3DSA:3.90.180.10 8 159 1.7E-28 T 23-04-2016 IPR011032 GroES-like DC74_RS26645 f573fefbc4de4496c575d36e3870fb5e 320 PANTHER PTHR11695 18 320 4.3E-90 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS36150 97b49fd0d55bade254de80b38f45545c 124 Pfam PF13586 Transposase DDE domain 39 117 4.7E-10 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS36150 97b49fd0d55bade254de80b38f45545c 124 PANTHER PTHR30007 1 120 3.1E-16 T 23-04-2016 DC74_RS17540 f644b90d434d86a459bd8db45bce37ea 684 Gene3D G3DSA:3.20.20.80 5 379 2.7E-130 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS17540 f644b90d434d86a459bd8db45bce37ea 684 SUPERFAMILY SSF52317 386 605 2.14E-53 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS17540 f644b90d434d86a459bd8db45bce37ea 684 PANTHER PTHR36447 3 676 4.5E-235 T 23-04-2016 DC74_RS17540 f644b90d434d86a459bd8db45bce37ea 684 SUPERFAMILY SSF51445 5 380 4.5E-110 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS17540 f644b90d434d86a459bd8db45bce37ea 684 Pfam PF02449 Beta-galactosidase 8 377 2.6E-143 T 23-04-2016 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 DC74_RS17540 f644b90d434d86a459bd8db45bce37ea 684 Gene3D G3DSA:3.40.50.880 386 608 2.7E-68 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS17540 f644b90d434d86a459bd8db45bce37ea 684 PANTHER PTHR36447:SF1 3 676 4.5E-235 T 23-04-2016 DC74_RS17540 f644b90d434d86a459bd8db45bce37ea 684 Pfam PF08533 Beta-galactosidase C-terminal domain 615 671 5.1E-7 T 23-04-2016 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 DC74_RS17540 f644b90d434d86a459bd8db45bce37ea 684 Pfam PF08532 Beta-galactosidase trimerisation domain 388 605 2.1E-57 T 23-04-2016 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 DC74_RS17540 f644b90d434d86a459bd8db45bce37ea 684 PIRSF PIRSF001084 1 674 1.2E-246 T 23-04-2016 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 DC74_RS33550 6bf6f07ef08944bcc94c7cc6d72b9fe5 474 PANTHER PTHR14463:SF9 1 466 4.0E-241 T 23-04-2016 DC74_RS33550 6bf6f07ef08944bcc94c7cc6d72b9fe5 474 Pfam PF06762 Lipase maturation factor 284 466 2.2E-62 T 23-04-2016 IPR009613 Lipase maturation factor DC74_RS33550 6bf6f07ef08944bcc94c7cc6d72b9fe5 474 Pfam PF06762 Lipase maturation factor 121 266 4.1E-55 T 23-04-2016 IPR009613 Lipase maturation factor DC74_RS33550 6bf6f07ef08944bcc94c7cc6d72b9fe5 474 PANTHER PTHR14463 1 466 4.0E-241 T 23-04-2016 DC74_RS30695 72c85e87c354fd4523db12fb9f8a818e 489 Pfam PF10935 Protein of unknown function (DUF2637) 46 160 2.1E-9 T 23-04-2016 IPR021235 Protein of unknown function DUF2637 DC74_RS37925 fe26561b2b9d124a1156327ad1b076f6 516 Pfam PF13460 NAD(P)H-binding 20 163 1.7E-20 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37925 fe26561b2b9d124a1156327ad1b076f6 516 PANTHER PTHR10366:SF401 15 274 9.4E-100 T 23-04-2016 DC74_RS37925 fe26561b2b9d124a1156327ad1b076f6 516 Gene3D G3DSA:3.40.50.720 9 236 9.0E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37925 fe26561b2b9d124a1156327ad1b076f6 516 SUPERFAMILY SSF55961 356 500 1.55E-10 T 23-04-2016 DC74_RS37925 fe26561b2b9d124a1156327ad1b076f6 516 PANTHER PTHR10366 15 274 9.4E-100 T 23-04-2016 DC74_RS37925 fe26561b2b9d124a1156327ad1b076f6 516 Pfam PF11066 Protein of unknown function (DUF2867) 345 490 7.9E-42 T 23-04-2016 IPR021295 Protein of unknown function DUF2867 DC74_RS37925 fe26561b2b9d124a1156327ad1b076f6 516 SUPERFAMILY SSF51735 15 294 5.34E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS14760 420e159e41c303efaee0e025744a36d0 315 PANTHER PTHR30468 56 315 2.4E-80 T 23-04-2016 DC74_RS14760 420e159e41c303efaee0e025744a36d0 315 Gene3D G3DSA:3.60.130.10 47 315 5.8E-88 T 23-04-2016 DC74_RS14760 420e159e41c303efaee0e025744a36d0 315 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 53 304 6.9E-61 T 23-04-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 DC74_RS14760 420e159e41c303efaee0e025744a36d0 315 SUPERFAMILY SSF51197 47 315 3.57E-86 T 23-04-2016 DC74_RS27725 16ebc41bc2ab21bc51629c3a0f66cd9d 308 SUPERFAMILY SSF51730 35 303 7.45E-70 T 23-04-2016 IPR029041 FAD-linked oxidoreductase-like DC74_RS27725 16ebc41bc2ab21bc51629c3a0f66cd9d 308 PIRSF PIRSF000196 1 308 2.1E-113 T 23-04-2016 IPR008219 Proline dehydrogenase GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|UniPathway: UPA00261 DC74_RS27725 16ebc41bc2ab21bc51629c3a0f66cd9d 308 Pfam PF01619 Proline dehydrogenase 46 299 1.2E-31 T 23-04-2016 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|UniPathway: UPA00261 DC74_RS27725 16ebc41bc2ab21bc51629c3a0f66cd9d 308 Gene3D G3DSA:3.20.20.220 34 302 1.0E-69 T 23-04-2016 IPR029041 FAD-linked oxidoreductase-like DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 Gene3D G3DSA:1.10.630.10 13 419 3.6E-126 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 SUPERFAMILY SSF48264 21 418 7.6E-95 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 PRINTS PR00359 B-class P450 signature 291 302 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 PRINTS PR00359 B-class P450 signature 309 336 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 PRINTS PR00359 B-class P450 signature 358 367 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 PRINTS PR00359 B-class P450 signature 174 189 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 PRINTS PR00359 B-class P450 signature 337 352 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 PRINTS PR00359 B-class P450 signature 367 378 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 PRINTS PR00359 B-class P450 signature 157 173 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 PRINTS PR00359 B-class P450 signature 107 118 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 PRINTS PR00359 B-class P450 signature 210 232 1.2E-50 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 Pfam PF00067 Cytochrome P450 203 283 1.6E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 Pfam PF00067 Cytochrome P450 288 388 3.1E-19 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03600 8da057588ce8e734d05deaa9a47e29e1 423 PANTHER PTHR11712 18 416 2.7E-89 T 23-04-2016 DC74_RS22760 df1076c1152411ee4ef367a2b1d1752a 316 SUPERFAMILY SSF88659 120 184 6.92E-11 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS22760 df1076c1152411ee4ef367a2b1d1752a 316 SUPERFAMILY SSF88946 21 100 4.32E-12 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS22760 df1076c1152411ee4ef367a2b1d1752a 316 SUPERFAMILY SSF54427 193 311 1.62E-19 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS22760 df1076c1152411ee4ef367a2b1d1752a 316 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 182 6.9E-15 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS22760 df1076c1152411ee4ef367a2b1d1752a 316 Pfam PF12680 SnoaL-like domain 198 298 1.7E-7 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS22760 df1076c1152411ee4ef367a2b1d1752a 316 Pfam PF04542 Sigma-70 region 2 21 84 1.5E-12 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS22760 df1076c1152411ee4ef367a2b1d1752a 316 Gene3D G3DSA:1.10.1740.10 21 86 9.2E-11 T 23-04-2016 DC74_RS22760 df1076c1152411ee4ef367a2b1d1752a 316 Gene3D G3DSA:3.10.450.50 192 311 4.1E-17 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS22760 df1076c1152411ee4ef367a2b1d1752a 316 PANTHER PTHR30173 20 311 3.9E-100 T 23-04-2016 DC74_RS22760 df1076c1152411ee4ef367a2b1d1752a 316 Gene3D G3DSA:1.10.10.10 124 183 2.9E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22760 df1076c1152411ee4ef367a2b1d1752a 316 PANTHER PTHR30173:SF11 20 311 3.9E-100 T 23-04-2016 DC74_RS22760 df1076c1152411ee4ef367a2b1d1752a 316 Pfam PF08281 Sigma-70, region 4 128 179 1.7E-10 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS22910 892b32f5412e24012314619a55291896 527 Pfam PF01565 FAD binding domain 93 226 2.7E-29 T 23-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DC74_RS22910 892b32f5412e24012314619a55291896 527 PANTHER PTHR11748 53 520 1.6E-128 T 23-04-2016 DC74_RS22910 892b32f5412e24012314619a55291896 527 PANTHER PTHR11748:SF86 53 520 1.6E-128 T 23-04-2016 DC74_RS22910 892b32f5412e24012314619a55291896 527 Gene3D G3DSA:3.30.465.10 152 260 3.8E-14 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS22910 892b32f5412e24012314619a55291896 527 SUPERFAMILY SSF56176 53 260 2.43E-52 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS22910 892b32f5412e24012314619a55291896 527 Pfam PF08031 Berberine and berberine like 483 521 5.3E-10 T 23-04-2016 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 DC74_RS22910 892b32f5412e24012314619a55291896 527 Gene3D G3DSA:3.30.43.10 48 147 1.1E-7 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS22910 892b32f5412e24012314619a55291896 527 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 93 126 - T 23-04-2016 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 DC74_RS21745 3709ee52373944c0f125abe94dc3c7b7 155 Gene3D G3DSA:3.10.450.50 17 141 6.2E-61 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS21745 3709ee52373944c0f125abe94dc3c7b7 155 PANTHER PTHR31757:SF0 2 155 5.5E-66 T 23-04-2016 DC74_RS21745 3709ee52373944c0f125abe94dc3c7b7 155 SUPERFAMILY SSF54427 5 145 2.85E-65 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS21745 3709ee52373944c0f125abe94dc3c7b7 155 Pfam PF07080 Protein of unknown function (DUF1348) 7 144 1.9E-63 T 23-04-2016 IPR009783 Protein of unknown function DUF1348 DC74_RS21745 3709ee52373944c0f125abe94dc3c7b7 155 PANTHER PTHR31757 2 155 5.5E-66 T 23-04-2016 DC74_RS06110 87912498af163c61c9d9973decf8bd22 122 SUPERFAMILY SSF50346 16 114 4.97E-17 T 23-04-2016 IPR011033 PRC-barrel-like DC74_RS06110 87912498af163c61c9d9973decf8bd22 122 Gene3D G3DSA:2.30.30.240 22 85 3.7E-4 T 23-04-2016 DC74_RS08185 a22998a6ef89b0188beffd4d4ed282e4 270 SUPERFAMILY SSF161098 5 261 2.09E-49 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS08185 a22998a6ef89b0188beffd4d4ed282e4 270 PANTHER PTHR30193:SF20 3 264 2.0E-65 T 23-04-2016 DC74_RS08185 a22998a6ef89b0188beffd4d4ed282e4 270 PANTHER PTHR30193 3 264 2.0E-65 T 23-04-2016 DC74_RS08185 a22998a6ef89b0188beffd4d4ed282e4 270 Gene3D G3DSA:1.10.3720.10 11 262 1.1E-47 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS08185 a22998a6ef89b0188beffd4d4ed282e4 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 260 3.8E-18 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS21465 394f0cedff39a5ce7401e8ac345ef3c5 254 SUPERFAMILY SSF52218 1 238 1.86E-63 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS21465 394f0cedff39a5ce7401e8ac345ef3c5 254 Pfam PF02525 Flavodoxin-like fold 1 213 3.9E-54 T 23-04-2016 IPR003680 Flavodoxin-like fold DC74_RS21465 394f0cedff39a5ce7401e8ac345ef3c5 254 Gene3D G3DSA:3.40.50.360 1 232 1.5E-67 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS21465 394f0cedff39a5ce7401e8ac345ef3c5 254 PANTHER PTHR10204 1 214 2.9E-73 T 23-04-2016 DC74_RS21465 394f0cedff39a5ce7401e8ac345ef3c5 254 PANTHER PTHR10204:SF46 1 214 2.9E-73 T 23-04-2016 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 67 195 7.6E-49 T 23-04-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 SUPERFAMILY SSF51735 213 457 9.85E-70 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 213 456 2.7E-83 T 23-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 SUPERFAMILY SSF53223 20 207 8.0E-73 T 23-04-2016 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 124 138 3.3E-28 T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 382 393 3.3E-28 T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 204 226 3.3E-28 T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 246 266 3.3E-28 T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 PIRSF PIRSF000185 32 458 4.0E-115 T 23-04-2016 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 Gene3D G3DSA:1.10.285.10 383 457 3.4E-22 T 23-04-2016 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 Gene3D G3DSA:1.10.285.10 23 77 1.5E-22 T 23-04-2016 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 SMART SM00839 215 456 2.3E-82 T 23-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 PANTHER PTHR11606:SF4 17 458 7.9E-243 T 23-04-2016 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 Gene3D G3DSA:3.40.50.720 220 382 2.1E-57 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 PANTHER PTHR11606 17 458 7.9E-243 T 23-04-2016 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 132 145 - T 23-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 DC74_RS27550 2d90686fa12b8b504d759124f83a5ded 458 Gene3D G3DSA:3.40.192.10 78 199 1.0E-60 T 23-04-2016 DC74_RS38360 9610bb7c6b8f26dd71a3fbb5db1c8b04 333 PANTHER PTHR10314 25 307 1.2E-67 T 23-04-2016 DC74_RS38360 9610bb7c6b8f26dd71a3fbb5db1c8b04 333 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 11 307 5.2E-118 T 23-04-2016 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA DC74_RS38360 9610bb7c6b8f26dd71a3fbb5db1c8b04 333 SUPERFAMILY SSF53686 20 309 2.23E-66 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS38360 9610bb7c6b8f26dd71a3fbb5db1c8b04 333 PANTHER PTHR10314:SF109 25 307 1.2E-67 T 23-04-2016 DC74_RS38360 9610bb7c6b8f26dd71a3fbb5db1c8b04 333 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 275 8.6E-47 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS38360 9610bb7c6b8f26dd71a3fbb5db1c8b04 333 Gene3D G3DSA:3.40.50.1100 35 136 9.0E-22 T 23-04-2016 DC74_RS38360 9610bb7c6b8f26dd71a3fbb5db1c8b04 333 Gene3D G3DSA:3.40.50.1100 137 306 3.2E-48 T 23-04-2016 DC74_RS31450 be4036080e9a21913bde24ea8fc4e843 210 Gene3D G3DSA:2.60.120.10 90 189 2.5E-18 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS31450 be4036080e9a21913bde24ea8fc4e843 210 Pfam PF07883 Cupin domain 120 186 2.2E-13 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS31450 be4036080e9a21913bde24ea8fc4e843 210 Gene3D G3DSA:1.10.260.40 14 89 1.4E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS31450 be4036080e9a21913bde24ea8fc4e843 210 SUPERFAMILY SSF47413 16 86 1.69E-15 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS31450 be4036080e9a21913bde24ea8fc4e843 210 PANTHER PTHR10245:SF20 12 191 1.5E-30 T 23-04-2016 DC74_RS31450 be4036080e9a21913bde24ea8fc4e843 210 Pfam PF13560 Helix-turn-helix domain 20 77 9.7E-15 T 23-04-2016 DC74_RS31450 be4036080e9a21913bde24ea8fc4e843 210 PANTHER PTHR10245 12 191 1.5E-30 T 23-04-2016 DC74_RS31450 be4036080e9a21913bde24ea8fc4e843 210 SMART SM00530 23 78 7.5E-15 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS31450 be4036080e9a21913bde24ea8fc4e843 210 SUPERFAMILY SSF51182 63 188 4.46E-22 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 ProSitePatterns PS00018 EF-hand calcium-binding domain. 442 454 - T 23-04-2016 IPR018247 EF-Hand 1, calcium-binding site DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 ProSitePatterns PS00018 EF-hand calcium-binding domain. 365 377 - T 23-04-2016 IPR018247 EF-Hand 1, calcium-binding site DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 14 250 4.1E-32 T 23-04-2016 IPR018713 Domain of unknown function DUF2236 DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 SMART SM00054 433 461 7.7E-4 T 23-04-2016 IPR002048 EF-hand domain GO:0005509 DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 SMART SM00054 399 427 0.034 T 23-04-2016 IPR002048 EF-hand domain GO:0005509 DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 SMART SM00054 306 335 91.0 T 23-04-2016 IPR002048 EF-hand domain GO:0005509 DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 SMART SM00054 356 384 35.0 T 23-04-2016 IPR002048 EF-hand domain GO:0005509 DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 Gene3D G3DSA:1.10.238.10 304 465 1.5E-26 T 23-04-2016 IPR011992 EF-hand domain pair DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 SUPERFAMILY SSF47473 304 462 1.51E-27 T 23-04-2016 IPR011992 EF-hand domain pair DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 Pfam PF13499 EF-hand domain pair 307 380 3.1E-7 T 23-04-2016 IPR002048 EF-hand domain GO:0005509 DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 Pfam PF13499 EF-hand domain pair 399 458 6.5E-9 T 23-04-2016 IPR002048 EF-hand domain GO:0005509 DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 ProSitePatterns PS00018 EF-hand calcium-binding domain. 408 420 - T 23-04-2016 IPR018247 EF-Hand 1, calcium-binding site DC74_RS36600 17f731671abec1ceac8ec19d60a16bd4 478 PANTHER PTHR36151 7 302 8.5E-30 T 23-04-2016 DC74_RS11135 e030c89b9d24bcac34bfd66694346062 331 SUPERFAMILY SSF81345 5 322 9.15E-70 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS11135 e030c89b9d24bcac34bfd66694346062 331 PANTHER PTHR30472:SF24 1 330 6.5E-139 T 23-04-2016 DC74_RS11135 e030c89b9d24bcac34bfd66694346062 331 Gene3D G3DSA:1.10.3470.10 6 327 2.2E-89 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS11135 e030c89b9d24bcac34bfd66694346062 331 PANTHER PTHR30472 1 330 6.5E-139 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS11135 e030c89b9d24bcac34bfd66694346062 331 Pfam PF01032 FecCD transport family 19 323 3.1E-79 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS18265 72fbfd25fcb65300c23e11397c3ad3b9 142 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 14 47 5.5E-13 T 23-04-2016 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DC74_RS18265 72fbfd25fcb65300c23e11397c3ad3b9 142 SUPERFAMILY SSF50249 3 133 5.14E-32 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS18265 72fbfd25fcb65300c23e11397c3ad3b9 142 PANTHER PTHR34075:SF2 13 130 2.3E-19 T 23-04-2016 DC74_RS18265 72fbfd25fcb65300c23e11397c3ad3b9 142 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 51 126 9.5E-19 T 23-04-2016 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal DC74_RS18265 72fbfd25fcb65300c23e11397c3ad3b9 142 PANTHER PTHR34075 13 130 2.3E-19 T 23-04-2016 DC74_RS33445 c39b28aef2a55bc1558a82f2d0fd0608 172 SUPERFAMILY SSF54637 22 165 4.48E-35 T 23-04-2016 IPR029069 HotDog domain DC74_RS33445 c39b28aef2a55bc1558a82f2d0fd0608 172 Pfam PF13279 Thioesterase-like superfamily 26 151 9.2E-16 T 23-04-2016 DC74_RS33445 c39b28aef2a55bc1558a82f2d0fd0608 172 PANTHER PTHR31793 22 171 1.2E-48 T 23-04-2016 DC74_RS33445 c39b28aef2a55bc1558a82f2d0fd0608 172 PANTHER PTHR31793:SF2 22 171 1.2E-48 T 23-04-2016 DC74_RS33445 c39b28aef2a55bc1558a82f2d0fd0608 172 Gene3D G3DSA:3.10.129.10 18 156 1.2E-46 T 23-04-2016 IPR029069 HotDog domain DC74_RS06425 804bd736d100638f5c31230f7e442f40 138 Pfam PF09851 Short C-terminal domain 110 137 2.2E-8 T 23-04-2016 IPR018649 SHOCT domain DC74_RS06425 804bd736d100638f5c31230f7e442f40 138 Pfam PF13396 Phospholipase_D-nuclease N-terminal 27 73 2.1E-7 T 23-04-2016 IPR027379 Cardiolipin synthase N-terminal DC74_RS10665 6b54ab4e7b4a40448b3e19823ac7865c 940 Gene3D G3DSA:1.10.439.10 121 282 9.5E-37 T 23-04-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 DC74_RS10665 6b54ab4e7b4a40448b3e19823ac7865c 940 PANTHER PTHR34218:SF2 67 363 4.4E-124 T 23-04-2016 DC74_RS10665 6b54ab4e7b4a40448b3e19823ac7865c 940 PANTHER PTHR34218:SF2 404 936 4.4E-124 T 23-04-2016 DC74_RS10665 6b54ab4e7b4a40448b3e19823ac7865c 940 Gene3D G3DSA:3.60.20.10 580 820 1.4E-67 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS10665 6b54ab4e7b4a40448b3e19823ac7865c 940 Gene3D G3DSA:3.60.20.10 408 487 1.4E-67 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS10665 6b54ab4e7b4a40448b3e19823ac7865c 940 SUPERFAMILY SSF56235 400 813 3.86E-98 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS10665 6b54ab4e7b4a40448b3e19823ac7865c 940 SUPERFAMILY SSF56235 123 327 3.86E-98 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS10665 6b54ab4e7b4a40448b3e19823ac7865c 940 PANTHER PTHR34218 67 363 4.4E-124 T 23-04-2016 DC74_RS10665 6b54ab4e7b4a40448b3e19823ac7865c 940 PANTHER PTHR34218 404 936 4.4E-124 T 23-04-2016 DC74_RS10665 6b54ab4e7b4a40448b3e19823ac7865c 940 Pfam PF01804 Penicillin amidase 123 927 2.5E-125 T 23-04-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 DC74_RS32055 c048d481969e6c56ffb1d28f133a4977 295 SUPERFAMILY SSF53927 4 286 5.72E-78 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS32055 c048d481969e6c56ffb1d28f133a4977 295 Gene3D G3DSA:3.10.20.10 28 131 2.5E-27 T 23-04-2016 DC74_RS32055 c048d481969e6c56ffb1d28f133a4977 295 Pfam PF02634 FdhD/NarQ family 26 286 3.3E-81 T 23-04-2016 IPR003786 Protein FdhD GO:0016783 DC74_RS32055 c048d481969e6c56ffb1d28f133a4977 295 Hamap MF_00187 Protein FdhD [fdhD]. 3 287 36.879 T 23-04-2016 IPR003786 Protein FdhD GO:0016783 DC74_RS32055 c048d481969e6c56ffb1d28f133a4977 295 PIRSF PIRSF015626 1 291 9.8E-87 T 23-04-2016 IPR003786 Protein FdhD GO:0016783 DC74_RS32055 c048d481969e6c56ffb1d28f133a4977 295 Gene3D G3DSA:3.40.140.10 150 290 2.4E-56 T 23-04-2016 DC74_RS32055 c048d481969e6c56ffb1d28f133a4977 295 PANTHER PTHR30592 94 295 9.5E-101 T 23-04-2016 DC74_RS32055 c048d481969e6c56ffb1d28f133a4977 295 PANTHER PTHR30592 2 76 9.5E-101 T 23-04-2016 DC74_RS32055 c048d481969e6c56ffb1d28f133a4977 295 PANTHER PTHR30592:SF1 94 295 9.5E-101 T 23-04-2016 DC74_RS32055 c048d481969e6c56ffb1d28f133a4977 295 PANTHER PTHR30592:SF1 2 76 9.5E-101 T 23-04-2016 DC74_RS19990 75edd4474eb1f1f71281e03392e5bf5c 99 Gene3D G3DSA:1.10.287.1060 5 96 3.4E-6 T 23-04-2016 DC74_RS19990 75edd4474eb1f1f71281e03392e5bf5c 99 SUPERFAMILY SSF140453 5 98 1.44E-8 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS19990 75edd4474eb1f1f71281e03392e5bf5c 99 Pfam PF06013 Proteins of 100 residues with WXG 5 91 2.1E-11 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS00285 5dd84d93a46150569fa8f39aed8b3669 119 SUPERFAMILY SSF102405 1 98 2.75E-5 T 23-04-2016 DC74_RS26505 79c6837f4694416d13fcb9cec0de15d3 86 Gene3D G3DSA:3.30.40.10 2 86 5.5E-23 T 23-04-2016 IPR013083 Zinc finger, RING/FYVE/PHD-type DC74_RS26505 79c6837f4694416d13fcb9cec0de15d3 86 SUPERFAMILY SSF57850 2 86 1.88E-26 T 23-04-2016 DC74_RS26505 79c6837f4694416d13fcb9cec0de15d3 86 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 34 84 5.3E-11 T 23-04-2016 IPR001607 Zinc finger, UBP-type GO:0008270 DC74_RS26505 79c6837f4694416d13fcb9cec0de15d3 86 PANTHER PTHR24007 1 82 2.0E-20 T 23-04-2016 DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 2.4E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 2.4E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 2.4E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 2.2E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 2.2E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 2.2E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.2E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 2.2E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 PANTHER PTHR24322 146 177 8.7E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 PANTHER PTHR24322 2 130 8.7E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 SUPERFAMILY SSF51735 1 238 2.6E-75 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 4 236 1.2E-64 T 23-04-2016 DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 Gene3D G3DSA:3.40.50.720 1 238 2.9E-77 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36830 c287404988ff9213ed6ef34ab008532f 239 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 181 0.0013 T 23-04-2016 DC74_RS29765 11f5379b294f16d2df4110969f907578 709 Pfam PF00378 Enoyl-CoA hydratase/isomerase 52 239 4.0E-18 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS29765 11f5379b294f16d2df4110969f907578 709 PANTHER PTHR23309:SF2 53 695 0.0 T 23-04-2016 DC74_RS29765 11f5379b294f16d2df4110969f907578 709 SUPERFAMILY SSF52096 253 328 2.02E-34 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS29765 11f5379b294f16d2df4110969f907578 709 SUPERFAMILY SSF52096 34 220 2.02E-34 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS29765 11f5379b294f16d2df4110969f907578 709 SUPERFAMILY SSF48179 634 696 6.46E-10 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS29765 11f5379b294f16d2df4110969f907578 709 PANTHER PTHR23309 53 695 0.0 T 23-04-2016 DC74_RS29765 11f5379b294f16d2df4110969f907578 709 Gene3D G3DSA:1.10.1040.10 526 611 5.3E-11 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS29765 11f5379b294f16d2df4110969f907578 709 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 524 606 1.7E-11 T 23-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS29765 11f5379b294f16d2df4110969f907578 709 Gene3D G3DSA:3.40.50.720 335 525 7.1E-55 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29765 11f5379b294f16d2df4110969f907578 709 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 340 520 2.2E-57 T 23-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS29765 11f5379b294f16d2df4110969f907578 709 SUPERFAMILY SSF48179 522 615 3.66E-18 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS29765 11f5379b294f16d2df4110969f907578 709 Gene3D G3DSA:3.90.226.10 27 244 2.3E-36 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS29765 11f5379b294f16d2df4110969f907578 709 SUPERFAMILY SSF51735 338 522 7.37E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11925 54b9e53a50f487f544377b76c3036dcd 661 PANTHER PTHR32097:SF4 1 298 1.1E-54 T 23-04-2016 DC74_RS11925 54b9e53a50f487f544377b76c3036dcd 661 PANTHER PTHR32097:SF4 401 557 1.1E-54 T 23-04-2016 DC74_RS11925 54b9e53a50f487f544377b76c3036dcd 661 Gene3D G3DSA:2.60.60.30 63 162 1.7E-12 T 23-04-2016 DC74_RS11925 54b9e53a50f487f544377b76c3036dcd 661 Pfam PF02342 TerD domain 63 162 3.0E-14 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS11925 54b9e53a50f487f544377b76c3036dcd 661 PANTHER PTHR32097 1 298 1.1E-54 T 23-04-2016 DC74_RS11925 54b9e53a50f487f544377b76c3036dcd 661 PANTHER PTHR32097 401 557 1.1E-54 T 23-04-2016 DC74_RS14855 30bd25fcf1016522f71a6e702aa00abb 297 Pfam PF00950 ABC 3 transport family 6 261 2.3E-66 T 23-04-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 DC74_RS14855 30bd25fcf1016522f71a6e702aa00abb 297 PANTHER PTHR30477:SF0 1 277 5.8E-100 T 23-04-2016 DC74_RS14855 30bd25fcf1016522f71a6e702aa00abb 297 SUPERFAMILY SSF81345 3 258 1.16E-34 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS14855 30bd25fcf1016522f71a6e702aa00abb 297 PANTHER PTHR30477 1 277 5.8E-100 T 23-04-2016 DC74_RS14855 30bd25fcf1016522f71a6e702aa00abb 297 Gene3D G3DSA:1.10.3470.10 41 258 4.5E-10 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS08650 23cb07410b33ccc648bbee087a920a9d 555 SUPERFAMILY SSF51338 6 70 5.85E-28 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS08650 23cb07410b33ccc648bbee087a920a9d 555 SUPERFAMILY SSF51338 510 553 5.85E-28 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS08650 23cb07410b33ccc648bbee087a920a9d 555 Gene3D G3DSA:2.30.40.10 495 552 2.1E-5 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS08650 23cb07410b33ccc648bbee087a920a9d 555 Gene3D G3DSA:2.30.40.10 4 112 7.2E-22 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS08650 23cb07410b33ccc648bbee087a920a9d 555 PANTHER PTHR22642:SF2 11 552 9.8E-145 T 23-04-2016 DC74_RS08650 23cb07410b33ccc648bbee087a920a9d 555 PANTHER PTHR22642 11 552 9.8E-145 T 23-04-2016 DC74_RS08650 23cb07410b33ccc648bbee087a920a9d 555 Gene3D G3DSA:3.20.20.140 217 494 4.3E-29 T 23-04-2016 DC74_RS08650 23cb07410b33ccc648bbee087a920a9d 555 Pfam PF07969 Amidohydrolase family 59 551 1.4E-90 T 23-04-2016 IPR013108 Amidohydrolase 3 DC74_RS08650 23cb07410b33ccc648bbee087a920a9d 555 SUPERFAMILY SSF51556 215 511 4.22E-34 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS08650 23cb07410b33ccc648bbee087a920a9d 555 SUPERFAMILY SSF51556 69 129 4.22E-34 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 Gene3D G3DSA:1.10.630.10 28 424 1.6E-110 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 Pfam PF00067 Cytochrome P450 224 394 2.2E-18 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 PANTHER PTHR24286 99 424 1.4E-84 T 23-04-2016 DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 SUPERFAMILY SSF48264 28 426 1.7E-86 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 PRINTS PR00359 B-class P450 signature 173 188 9.6E-36 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 PRINTS PR00359 B-class P450 signature 105 116 9.6E-36 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 PRINTS PR00359 B-class P450 signature 364 373 9.6E-36 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 PRINTS PR00359 B-class P450 signature 310 337 9.6E-36 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 PRINTS PR00359 B-class P450 signature 210 232 9.6E-36 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 PRINTS PR00359 B-class P450 signature 292 303 9.6E-36 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 PRINTS PR00359 B-class P450 signature 156 172 9.6E-36 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 PRINTS PR00359 B-class P450 signature 373 384 9.6E-36 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS01580 ca2539d5ff9b89726552248f755ab4ad 427 PANTHER PTHR24286:SF42 99 424 1.4E-84 T 23-04-2016 DC74_RS37125 f7bdbd55cc6804393ac8e0eeed4fc1de 483 Pfam PF01425 Amidase 41 455 1.8E-89 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS37125 f7bdbd55cc6804393ac8e0eeed4fc1de 483 PANTHER PTHR11895:SF35 1 473 1.1E-205 T 23-04-2016 DC74_RS37125 f7bdbd55cc6804393ac8e0eeed4fc1de 483 Gene3D G3DSA:3.90.1300.10 5 471 5.5E-112 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS37125 f7bdbd55cc6804393ac8e0eeed4fc1de 483 SUPERFAMILY SSF75304 5 476 4.58E-115 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS37125 f7bdbd55cc6804393ac8e0eeed4fc1de 483 PANTHER PTHR11895 1 473 1.1E-205 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS37125 f7bdbd55cc6804393ac8e0eeed4fc1de 483 ProSitePatterns PS00571 Amidases signature. 145 176 - T 23-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS05380 ceb09080e9a7b8317ace3cfa0ebb7bb2 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 123 1.1E-19 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS05380 ceb09080e9a7b8317ace3cfa0ebb7bb2 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 220 1.6E-21 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS05380 ceb09080e9a7b8317ace3cfa0ebb7bb2 380 Gene3D G3DSA:2.40.110.10 126 222 3.2E-34 T 23-04-2016 DC74_RS05380 ceb09080e9a7b8317ace3cfa0ebb7bb2 380 SUPERFAMILY SSF47203 233 378 7.09E-18 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS05380 ceb09080e9a7b8317ace3cfa0ebb7bb2 380 Gene3D G3DSA:1.20.140.10 223 380 9.9E-28 T 23-04-2016 DC74_RS05380 ceb09080e9a7b8317ace3cfa0ebb7bb2 380 PANTHER PTHR10909:SF229 1 380 5.7E-94 T 23-04-2016 DC74_RS05380 ceb09080e9a7b8317ace3cfa0ebb7bb2 380 SUPERFAMILY SSF56645 2 245 1.31E-68 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS05380 ceb09080e9a7b8317ace3cfa0ebb7bb2 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 374 1.4E-15 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS05380 ceb09080e9a7b8317ace3cfa0ebb7bb2 380 Gene3D G3DSA:1.10.540.10 1 124 4.0E-23 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS05380 ceb09080e9a7b8317ace3cfa0ebb7bb2 380 PANTHER PTHR10909 1 380 5.7E-94 T 23-04-2016 DC74_RS12745 f0e9592a624e2c11c18896883299a2a2 235 SUPERFAMILY SSF69593 6 218 1.19E-49 T 23-04-2016 DC74_RS12745 f0e9592a624e2c11c18896883299a2a2 235 PANTHER PTHR10434:SF21 1 235 2.2E-95 T 23-04-2016 DC74_RS12745 f0e9592a624e2c11c18896883299a2a2 235 Gene3D G3DSA:3.40.1130.10 13 203 2.7E-30 T 23-04-2016 DC74_RS12745 f0e9592a624e2c11c18896883299a2a2 235 PANTHER PTHR10434 1 235 2.2E-95 T 23-04-2016 DC74_RS12745 f0e9592a624e2c11c18896883299a2a2 235 Pfam PF01553 Acyltransferase 17 147 3.0E-21 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS12745 f0e9592a624e2c11c18896883299a2a2 235 SMART SM00563 29 150 3.6E-34 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS17865 baa61466c287c367478ece049fddc0d3 428 Gene3D G3DSA:1.20.1250.20 17 205 4.9E-10 T 23-04-2016 DC74_RS17865 baa61466c287c367478ece049fddc0d3 428 Gene3D G3DSA:1.20.1250.20 224 397 1.2E-14 T 23-04-2016 DC74_RS17865 baa61466c287c367478ece049fddc0d3 428 Pfam PF07690 Major Facilitator Superfamily 32 345 1.2E-18 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS17865 baa61466c287c367478ece049fddc0d3 428 SUPERFAMILY SSF103473 16 399 5.62E-31 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS17865 baa61466c287c367478ece049fddc0d3 428 PANTHER PTHR23542:SF1 9 428 2.5E-124 T 23-04-2016 DC74_RS17865 baa61466c287c367478ece049fddc0d3 428 PANTHER PTHR23542 9 428 2.5E-124 T 23-04-2016 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 PRINTS PR00412 Epoxide hydrolase signature 37 55 4.1E-26 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 PRINTS PR00412 Epoxide hydrolase signature 301 323 4.1E-26 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 PRINTS PR00412 Epoxide hydrolase signature 57 72 4.1E-26 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 PRINTS PR00412 Epoxide hydrolase signature 117 130 4.1E-26 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 PRINTS PR00412 Epoxide hydrolase signature 103 116 4.1E-26 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 PANTHER PTHR10992 215 326 1.5E-139 T 23-04-2016 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 PANTHER PTHR10992 12 171 1.5E-139 T 23-04-2016 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 PANTHER PTHR10992:SF305 215 326 1.5E-139 T 23-04-2016 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 PANTHER PTHR10992:SF305 12 171 1.5E-139 T 23-04-2016 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 Gene3D G3DSA:3.40.50.1820 219 326 5.5E-83 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 Gene3D G3DSA:3.40.50.1820 8 187 5.5E-83 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 Pfam PF00561 alpha/beta hydrolase fold 31 312 4.1E-27 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 3.6E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 3.6E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 3.6E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36810 1b96cc999ed4f655fa6ac44a644b3047 329 SUPERFAMILY SSF53474 9 325 9.24E-67 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS06235 716aa5743b92444b130c744b26dcfade 198 Gene3D G3DSA:3.40.50.1240 25 184 4.6E-21 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS06235 716aa5743b92444b130c744b26dcfade 198 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 24 184 1.2E-22 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS06235 716aa5743b92444b130c744b26dcfade 198 SUPERFAMILY SSF53254 16 185 2.01E-26 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS19290 d551acb711fb950937c8585c374036e0 475 Pfam PF04185 Phosphoesterase family 47 402 3.4E-112 T 23-04-2016 IPR007312 Phosphoesterase GO:0016788 DC74_RS19290 d551acb711fb950937c8585c374036e0 475 PANTHER PTHR31956 4 425 1.9E-136 T 23-04-2016 DC74_RS19290 d551acb711fb950937c8585c374036e0 475 PANTHER PTHR31956:SF6 4 425 1.9E-136 T 23-04-2016 DC74_RS09290 4ad3757724f6be40be9482dd6f61ec7a 573 SUPERFAMILY SSF51905 48 381 2.59E-43 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS09290 4ad3757724f6be40be9482dd6f61ec7a 573 SUPERFAMILY SSF51905 475 549 2.59E-43 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS09290 4ad3757724f6be40be9482dd6f61ec7a 573 Gene3D G3DSA:3.50.50.60 45 78 1.7E-10 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS09290 4ad3757724f6be40be9482dd6f61ec7a 573 PANTHER PTHR10742 15 568 7.5E-123 T 23-04-2016 DC74_RS09290 4ad3757724f6be40be9482dd6f61ec7a 573 PANTHER PTHR10742:SF277 15 568 7.5E-123 T 23-04-2016 DC74_RS09290 4ad3757724f6be40be9482dd6f61ec7a 573 SUPERFAMILY SSF54373 366 486 1.5E-26 T 23-04-2016 DC74_RS09290 4ad3757724f6be40be9482dd6f61ec7a 573 Gene3D G3DSA:3.90.660.10 370 477 3.2E-25 T 23-04-2016 DC74_RS09290 4ad3757724f6be40be9482dd6f61ec7a 573 Gene3D G3DSA:3.90.660.10 79 158 3.2E-25 T 23-04-2016 DC74_RS09290 4ad3757724f6be40be9482dd6f61ec7a 573 Gene3D G3DSA:3.50.50.60 249 366 2.3E-11 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS09290 4ad3757724f6be40be9482dd6f61ec7a 573 Gene3D G3DSA:3.50.50.60 511 552 2.3E-11 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS09290 4ad3757724f6be40be9482dd6f61ec7a 573 Pfam PF01593 Flavin containing amine oxidoreductase 58 542 9.8E-45 T 23-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 DC74_RS07190 642f3c04c31da82babb9f11b5d5b2f8e 263 Gene3D G3DSA:3.10.180.10 14 124 8.5E-27 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS07190 642f3c04c31da82babb9f11b5d5b2f8e 263 Gene3D G3DSA:3.10.180.10 138 259 6.4E-18 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS07190 642f3c04c31da82babb9f11b5d5b2f8e 263 PANTHER PTHR33993 10 263 6.8E-74 T 23-04-2016 DC74_RS07190 642f3c04c31da82babb9f11b5d5b2f8e 263 SUPERFAMILY SSF54593 141 259 6.31E-14 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS07190 642f3c04c31da82babb9f11b5d5b2f8e 263 PANTHER PTHR33993:SF3 10 263 6.8E-74 T 23-04-2016 DC74_RS07190 642f3c04c31da82babb9f11b5d5b2f8e 263 SUPERFAMILY SSF54593 14 126 1.26E-16 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS27150 957d91df629b17a31b329819dca79386 146 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 136 4.3E-44 T 23-04-2016 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384 DC74_RS27150 957d91df629b17a31b329819dca79386 146 SUPERFAMILY SSF54593 1 138 3.58E-34 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS27150 957d91df629b17a31b329819dca79386 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 122 1.4E-20 T 23-04-2016 DC74_RS27150 957d91df629b17a31b329819dca79386 146 PANTHER PTHR21366:SF0 1 138 5.3E-38 T 23-04-2016 DC74_RS27150 957d91df629b17a31b329819dca79386 146 Gene3D G3DSA:3.10.180.10 1 136 2.0E-37 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS27150 957d91df629b17a31b329819dca79386 146 PANTHER PTHR21366 1 138 5.3E-38 T 23-04-2016 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 Gene3D G3DSA:1.10.287.610 100 153 3.7E-21 T 23-04-2016 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 23-04-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 42.085 T 23-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 SUPERFAMILY SSF52313 6 230 1.83E-90 T 23-04-2016 IPR023591 Ribosomal protein S2, flavodoxin-like domain DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 7.4E-107 T 23-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 PANTHER PTHR12534 1 270 1.6E-113 T 23-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 Gene3D G3DSA:3.40.50.10490 159 242 4.3E-67 T 23-04-2016 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 Gene3D G3DSA:3.40.50.10490 23 99 4.3E-67 T 23-04-2016 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 PRINTS PR00395 Ribosomal protein S2 signature 6 24 6.8E-39 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 PRINTS PR00395 Ribosomal protein S2 signature 37 46 6.8E-39 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 PRINTS PR00395 Ribosomal protein S2 signature 197 211 6.8E-39 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 PRINTS PR00395 Ribosomal protein S2 signature 87 104 6.8E-39 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 PRINTS PR00395 Ribosomal protein S2 signature 159 176 6.8E-39 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 PRINTS PR00395 Ribosomal protein S2 signature 176 187 6.8E-39 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28190 f7c9a49a5148dac4fe7f3d55a8bfb368 296 Pfam PF00318 Ribosomal protein S2 9 225 2.6E-95 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS19200 2e4e2330ffb0738ea8bc63fe4194c5fc 303 PANTHER PTHR10992 8 175 9.7E-38 T 23-04-2016 DC74_RS19200 2e4e2330ffb0738ea8bc63fe4194c5fc 303 PANTHER PTHR10992 197 298 9.7E-38 T 23-04-2016 DC74_RS19200 2e4e2330ffb0738ea8bc63fe4194c5fc 303 Pfam PF00561 alpha/beta hydrolase fold 33 134 1.5E-16 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS19200 2e4e2330ffb0738ea8bc63fe4194c5fc 303 PANTHER PTHR10992:SF771 8 175 9.7E-38 T 23-04-2016 DC74_RS19200 2e4e2330ffb0738ea8bc63fe4194c5fc 303 PANTHER PTHR10992:SF771 197 298 9.7E-38 T 23-04-2016 DC74_RS19200 2e4e2330ffb0738ea8bc63fe4194c5fc 303 SUPERFAMILY SSF53474 8 294 8.04E-48 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS19200 2e4e2330ffb0738ea8bc63fe4194c5fc 303 Gene3D G3DSA:3.40.50.1820 11 295 6.0E-55 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01700 6a210cb5740edf7c37259f3eb220759d 115 SMART SM00418 25 103 1.0E-11 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS01700 6a210cb5740edf7c37259f3eb220759d 115 Gene3D G3DSA:1.10.10.10 22 101 4.1E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01700 6a210cb5740edf7c37259f3eb220759d 115 Pfam PF12840 Helix-turn-helix domain 24 78 1.8E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01700 6a210cb5740edf7c37259f3eb220759d 115 SUPERFAMILY SSF46785 12 102 4.28E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01700 6a210cb5740edf7c37259f3eb220759d 115 PANTHER PTHR33154:SF2 14 113 3.7E-37 T 23-04-2016 DC74_RS01700 6a210cb5740edf7c37259f3eb220759d 115 PANTHER PTHR33154 14 113 3.7E-37 T 23-04-2016 DC74_RS16510 d50bcef0903d8c14265231aa5452fb51 435 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS16510 d50bcef0903d8c14265231aa5452fb51 435 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 42 390 6.3E-103 T 23-04-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 DC74_RS16510 d50bcef0903d8c14265231aa5452fb51 435 SUPERFAMILY SSF52540 26 265 4.03E-76 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16510 d50bcef0903d8c14265231aa5452fb51 435 PANTHER PTHR24220 385 401 9.6E-161 T 23-04-2016 DC74_RS16510 d50bcef0903d8c14265231aa5452fb51 435 PANTHER PTHR24220 27 302 9.6E-161 T 23-04-2016 DC74_RS16510 d50bcef0903d8c14265231aa5452fb51 435 Gene3D G3DSA:3.40.50.300 19 262 4.4E-78 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16510 d50bcef0903d8c14265231aa5452fb51 435 SUPERFAMILY SSF54631 275 387 5.23E-10 T 23-04-2016 DC74_RS16510 d50bcef0903d8c14265231aa5452fb51 435 SMART SM00382 52 248 5.8E-19 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS16510 d50bcef0903d8c14265231aa5452fb51 435 Pfam PF00005 ABC transporter 44 189 1.3E-34 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS16510 d50bcef0903d8c14265231aa5452fb51 435 Gene3D G3DSA:3.20.20.70 273 392 3.6E-7 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS16510 d50bcef0903d8c14265231aa5452fb51 435 PANTHER PTHR24220:SF350 385 401 9.6E-161 T 23-04-2016 DC74_RS16510 d50bcef0903d8c14265231aa5452fb51 435 PANTHER PTHR24220:SF350 27 302 9.6E-161 T 23-04-2016 DC74_RS32335 cec92e2a59515102ca6b2c2020498012 394 PANTHER PTHR23028 3 177 1.0E-38 T 23-04-2016 DC74_RS32335 cec92e2a59515102ca6b2c2020498012 394 PANTHER PTHR23028 193 373 1.0E-38 T 23-04-2016 DC74_RS32335 cec92e2a59515102ca6b2c2020498012 394 Pfam PF01757 Acyltransferase family 11 356 4.3E-31 T 23-04-2016 IPR002656 Acyltransferase 3 GO:0016747 DC74_RS33905 ddd9e69e908ec872811f04138dd72e45 258 Gene3D G3DSA:3.40.190.10 120 220 7.7E-24 T 23-04-2016 DC74_RS33905 ddd9e69e908ec872811f04138dd72e45 258 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 46 258 3.0E-55 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS33905 ddd9e69e908ec872811f04138dd72e45 258 SMART SM00062 41 258 4.4E-56 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS33905 ddd9e69e908ec872811f04138dd72e45 258 PANTHER PTHR18966 50 258 9.8E-33 T 23-04-2016 DC74_RS33905 ddd9e69e908ec872811f04138dd72e45 258 SUPERFAMILY SSF53850 13 258 2.73E-61 T 23-04-2016 DC74_RS33905 ddd9e69e908ec872811f04138dd72e45 258 Gene3D G3DSA:3.40.190.10 40 119 8.3E-35 T 23-04-2016 DC74_RS33905 ddd9e69e908ec872811f04138dd72e45 258 Gene3D G3DSA:3.40.190.10 221 258 8.3E-35 T 23-04-2016 DC74_RS33905 ddd9e69e908ec872811f04138dd72e45 258 PANTHER PTHR18966:SF191 50 258 9.8E-33 T 23-04-2016 DC74_RS33905 ddd9e69e908ec872811f04138dd72e45 258 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 63 76 - T 23-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 DC74_RS13110 dc9c58ed217f272365ea7585fca8b079 316 PIRSF PIRSF005963 3 316 5.3E-123 T 23-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 DC74_RS13110 dc9c58ed217f272365ea7585fca8b079 316 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 61 3.5E-6 T 23-04-2016 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 DC74_RS13110 dc9c58ed217f272365ea7585fca8b079 316 Pfam PF04055 Radical SAM superfamily 82 236 5.6E-13 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS13110 dc9c58ed217f272365ea7585fca8b079 316 PANTHER PTHR10949 10 311 5.3E-139 T 23-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 DC74_RS13110 dc9c58ed217f272365ea7585fca8b079 316 TIGRFAM TIGR00510 lipA: lipoyl synthase 18 306 2.7E-99 T 23-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 DC74_RS13110 dc9c58ed217f272365ea7585fca8b079 316 SUPERFAMILY SSF102114 36 309 4.05E-62 T 23-04-2016 DC74_RS13110 dc9c58ed217f272365ea7585fca8b079 316 Gene3D G3DSA:3.20.20.70 39 302 1.4E-65 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS13110 dc9c58ed217f272365ea7585fca8b079 316 SMART SM00729 72 281 1.2E-15 T 23-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 DC74_RS13110 dc9c58ed217f272365ea7585fca8b079 316 Hamap MF_00206 Lipoyl synthase [lipA]. 1 308 137.724 T 23-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 DC74_RS01255 0324c7aab2070998567ee42f885fc9e3 294 PANTHER PTHR21310:SF14 1 289 1.5E-67 T 23-04-2016 DC74_RS01255 0324c7aab2070998567ee42f885fc9e3 294 PANTHER PTHR21310 1 289 1.5E-67 T 23-04-2016 DC74_RS01255 0324c7aab2070998567ee42f885fc9e3 294 Gene3D G3DSA:3.90.1200.10 102 266 7.9E-30 T 23-04-2016 DC74_RS01255 0324c7aab2070998567ee42f885fc9e3 294 Pfam PF01636 Phosphotransferase enzyme family 33 259 8.1E-31 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS01255 0324c7aab2070998567ee42f885fc9e3 294 SUPERFAMILY SSF56112 15 266 3.96E-45 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS22435 59bb00347523213dea58bcf5aaaafcbf 179 SUPERFAMILY SSF53271 4 177 1.44E-54 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS22435 59bb00347523213dea58bcf5aaaafcbf 179 Gene3D G3DSA:3.40.50.2020 2 177 2.8E-80 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS22435 59bb00347523213dea58bcf5aaaafcbf 179 PANTHER PTHR22573:SF56 4 177 4.1E-84 T 23-04-2016 DC74_RS22435 59bb00347523213dea58bcf5aaaafcbf 179 PANTHER PTHR22573 4 177 4.1E-84 T 23-04-2016 DC74_RS22435 59bb00347523213dea58bcf5aaaafcbf 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 172 4.5E-65 T 23-04-2016 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620|UniPathway: UPA00591 DC74_RS22435 59bb00347523213dea58bcf5aaaafcbf 179 Pfam PF00156 Phosphoribosyl transferase domain 14 159 1.8E-25 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 SUPERFAMILY SSF53901 268 387 1.77E-35 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 PANTHER PTHR18919:SF95 1 390 9.5E-209 T 23-04-2016 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 23-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 Gene3D G3DSA:3.40.47.10 138 189 6.2E-57 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 Gene3D G3DSA:3.40.47.10 273 388 6.2E-57 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 80 98 - T 23-04-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 Pfam PF02803 Thiolase, C-terminal domain 267 387 3.9E-44 T 23-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 2 386 1.8E-136 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 ProSitePatterns PS00099 Thiolases active site. 370 383 - T 23-04-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 Pfam PF00108 Thiolase, N-terminal domain 1 258 4.2E-96 T 23-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 PANTHER PTHR18919 1 390 9.5E-209 T 23-04-2016 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 PIRSF PIRSF000429 1 390 2.0E-118 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 Gene3D G3DSA:3.40.47.10 190 272 1.3E-71 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 Gene3D G3DSA:3.40.47.10 1 119 1.3E-71 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS27155 20d764d3d0ef47b25584d07ddb1812ae 391 SUPERFAMILY SSF53901 1 266 8.86E-85 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS00515 6c1a81ada0c9e8a1f6472e4cc7517b61 276 Pfam PF01522 Polysaccharide deacetylase 86 207 7.4E-26 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS00515 6c1a81ada0c9e8a1f6472e4cc7517b61 276 PANTHER PTHR10587 87 270 6.8E-45 T 23-04-2016 DC74_RS00515 6c1a81ada0c9e8a1f6472e4cc7517b61 276 Gene3D G3DSA:3.20.20.370 79 270 2.0E-52 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS00515 6c1a81ada0c9e8a1f6472e4cc7517b61 276 SUPERFAMILY SSF88713 85 270 4.7E-50 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS33655 63dc43348e919869a2c3f89a127a5aff 71 Gene3D G3DSA:3.30.1660.10 3 69 5.8E-34 T 23-04-2016 IPR025543 Dodecin-like DC74_RS33655 63dc43348e919869a2c3f89a127a5aff 71 PANTHER PTHR39324:SF1 1 71 4.8E-24 T 23-04-2016 DC74_RS33655 63dc43348e919869a2c3f89a127a5aff 71 PANTHER PTHR39324 1 71 4.8E-24 T 23-04-2016 DC74_RS33655 63dc43348e919869a2c3f89a127a5aff 71 SUPERFAMILY SSF89807 4 68 7.32E-24 T 23-04-2016 IPR009923 Dodecin DC74_RS33655 63dc43348e919869a2c3f89a127a5aff 71 Pfam PF07311 Dodecin 5 68 3.2E-28 T 23-04-2016 IPR009923 Dodecin DC74_RS29820 3605befe15753af9babe1f30ba711979 245 Pfam PF06778 Chlorite dismutase 47 234 1.8E-74 T 23-04-2016 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase DC74_RS29820 3605befe15753af9babe1f30ba711979 245 PANTHER PTHR36843:SF1 1 245 1.1E-52 T 23-04-2016 DC74_RS29820 3605befe15753af9babe1f30ba711979 245 PANTHER PTHR36843 1 245 1.1E-52 T 23-04-2016 DC74_RS29820 3605befe15753af9babe1f30ba711979 245 SUPERFAMILY SSF54909 25 244 8.04E-77 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS29820 3605befe15753af9babe1f30ba711979 245 Gene3D G3DSA:3.30.70.1100 147 244 3.2E-41 T 23-04-2016 DC74_RS29820 3605befe15753af9babe1f30ba711979 245 Gene3D G3DSA:3.30.70.1030 31 146 1.3E-28 T 23-04-2016 DC74_RS07430 b01d548b77f5c49073379e627933cbaa 295 Pfam PF13649 Methyltransferase domain 57 149 4.8E-6 T 23-04-2016 DC74_RS07430 b01d548b77f5c49073379e627933cbaa 295 SUPERFAMILY SSF53335 32 150 1.01E-9 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS07430 b01d548b77f5c49073379e627933cbaa 295 Gene3D G3DSA:3.40.50.150 30 150 2.4E-7 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS09830 64af02ca2fe0ed52ec61f30eba6c1255 352 PANTHER PTHR24220 3 259 1.5E-135 T 23-04-2016 DC74_RS09830 64af02ca2fe0ed52ec61f30eba6c1255 352 SMART SM00930 257 332 5.8E-20 T 23-04-2016 IPR018449 NIL domain DC74_RS09830 64af02ca2fe0ed52ec61f30eba6c1255 352 SUPERFAMILY SSF55021 255 334 2.4E-17 T 23-04-2016 DC74_RS09830 64af02ca2fe0ed52ec61f30eba6c1255 352 Pfam PF00005 ABC transporter 21 175 9.7E-35 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS09830 64af02ca2fe0ed52ec61f30eba6c1255 352 SUPERFAMILY SSF52540 2 245 2.18E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09830 64af02ca2fe0ed52ec61f30eba6c1255 352 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS09830 64af02ca2fe0ed52ec61f30eba6c1255 352 Gene3D G3DSA:3.40.50.300 2 242 1.4E-82 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09830 64af02ca2fe0ed52ec61f30eba6c1255 352 Pfam PF09383 NIL domain 259 331 3.6E-18 T 23-04-2016 IPR018449 NIL domain DC74_RS09830 64af02ca2fe0ed52ec61f30eba6c1255 352 Gene3D G3DSA:3.30.70.260 243 333 4.0E-22 T 23-04-2016 DC74_RS09830 64af02ca2fe0ed52ec61f30eba6c1255 352 SMART SM00382 30 232 1.8E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS09830 64af02ca2fe0ed52ec61f30eba6c1255 352 PANTHER PTHR24220:SF186 3 259 1.5E-135 T 23-04-2016 IPR026253 Methionine import ATP-binding protein MetN GO:0005524|GO:0015821|GO:0042626 DC74_RS25395 ed7e713db4e7b7a9d7c2237647c46f18 239 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 107 217 3.1E-19 T 23-04-2016 IPR031571 Flp pilus assembly protein RcpC/CpaB domain DC74_RS25395 ed7e713db4e7b7a9d7c2237647c46f18 239 SMART SM00858 41 103 1.4E-5 T 23-04-2016 IPR013974 SAF domain DC74_RS25395 ed7e713db4e7b7a9d7c2237647c46f18 239 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 10 220 3.3E-25 T 23-04-2016 IPR017592 Pilus assembly, Flp-type CpaB DC74_RS25395 ed7e713db4e7b7a9d7c2237647c46f18 239 Pfam PF08666 SAF domain 46 102 2.5E-5 T 23-04-2016 IPR013974 SAF domain DC74_RS39915 9af2e105521f155f3fa74faef63200a4 184 Gene3D G3DSA:3.40.50.300 3 162 1.6E-15 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39915 9af2e105521f155f3fa74faef63200a4 184 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 70 161 8.1E-8 T 23-04-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 DC74_RS39915 9af2e105521f155f3fa74faef63200a4 184 SUPERFAMILY SSF52540 2 179 2.27E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25205 0c9495d68aeb1ba467710acb86a62f42 221 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 46 209 37.688 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 DC74_RS25205 0c9495d68aeb1ba467710acb86a62f42 221 Pfam PF01625 Peptide methionine sulfoxide reductase 50 203 1.9E-64 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 DC74_RS25205 0c9495d68aeb1ba467710acb86a62f42 221 PANTHER PTHR10173:SF36 7 207 1.5E-100 T 23-04-2016 DC74_RS25205 0c9495d68aeb1ba467710acb86a62f42 221 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 48 203 2.4E-64 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 DC74_RS25205 0c9495d68aeb1ba467710acb86a62f42 221 PANTHER PTHR10173 7 207 1.5E-100 T 23-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 DC74_RS25205 0c9495d68aeb1ba467710acb86a62f42 221 SUPERFAMILY SSF55068 26 213 1.23E-76 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 DC74_RS25205 0c9495d68aeb1ba467710acb86a62f42 221 Gene3D G3DSA:3.30.1060.10 25 203 2.0E-76 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 DC74_RS37130 8b7a3dd7679b482a12817e2f0c72a1dd 318 PANTHER PTHR11695 12 318 2.1E-74 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS37130 8b7a3dd7679b482a12817e2f0c72a1dd 318 Gene3D G3DSA:3.40.50.720 144 255 4.1E-15 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37130 8b7a3dd7679b482a12817e2f0c72a1dd 318 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 85 6.2E-10 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS37130 8b7a3dd7679b482a12817e2f0c72a1dd 318 Gene3D G3DSA:3.90.180.10 1 143 2.7E-46 T 23-04-2016 IPR011032 GroES-like DC74_RS37130 8b7a3dd7679b482a12817e2f0c72a1dd 318 SMART SM00829 8 316 7.9E-15 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS37130 8b7a3dd7679b482a12817e2f0c72a1dd 318 PANTHER PTHR11695:SF28 12 318 2.1E-74 T 23-04-2016 DC74_RS37130 8b7a3dd7679b482a12817e2f0c72a1dd 318 SUPERFAMILY SSF50129 1 143 6.85E-36 T 23-04-2016 IPR011032 GroES-like DC74_RS37130 8b7a3dd7679b482a12817e2f0c72a1dd 318 Pfam PF13602 Zinc-binding dehydrogenase 197 316 6.9E-14 T 23-04-2016 DC74_RS37130 8b7a3dd7679b482a12817e2f0c72a1dd 318 SUPERFAMILY SSF51735 109 280 2.73E-29 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32275 02548406cdc63987af56db18e12f112f 205 Pfam PF00072 Response regulator receiver domain 3 91 7.2E-20 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS32275 02548406cdc63987af56db18e12f112f 205 Gene3D G3DSA:3.40.50.2300 2 98 2.3E-29 T 23-04-2016 DC74_RS32275 02548406cdc63987af56db18e12f112f 205 SMART SM00862 125 203 6.3E-25 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS32275 02548406cdc63987af56db18e12f112f 205 Pfam PF00486 Transcriptional regulatory protein, C terminal 126 203 6.7E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS32275 02548406cdc63987af56db18e12f112f 205 PANTHER PTHR26402 1 203 1.0E-64 T 23-04-2016 DC74_RS32275 02548406cdc63987af56db18e12f112f 205 Gene3D G3DSA:1.10.10.10 105 203 5.7E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32275 02548406cdc63987af56db18e12f112f 205 SMART SM00448 1 90 1.1E-18 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS32275 02548406cdc63987af56db18e12f112f 205 SUPERFAMILY SSF52172 2 157 9.12E-30 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS32275 02548406cdc63987af56db18e12f112f 205 PANTHER PTHR26402:SF50 1 203 1.0E-64 T 23-04-2016 DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 PANTHER PTHR11751 121 144 2.5E-24 T 23-04-2016 DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 SMART SM00345 13 72 2.9E-14 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 Pfam PF07702 UTRA domain 93 229 2.9E-37 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 SUPERFAMILY SSF64288 60 234 3.3E-46 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 Gene3D G3DSA:1.10.10.10 2 74 7.2E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 PANTHER PTHR11751:SF10 121 144 2.5E-24 T 23-04-2016 DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 9.9E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 9.9E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 PANTHER PTHR11751 3 75 2.5E-24 T 23-04-2016 DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 SUPERFAMILY SSF46785 2 81 2.64E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 8.6E-16 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 Gene3D G3DSA:3.40.1410.10 75 233 1.8E-49 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 SMART SM00866 92 230 1.7E-34 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS31495 ee708f31da74c60c2303eb248125e29b 239 PANTHER PTHR11751:SF10 3 75 2.5E-24 T 23-04-2016 DC74_RS10240 2337c8589fb3855584cb8d15192b92c9 374 Pfam PF00296 Luciferase-like monooxygenase 11 328 3.7E-74 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10240 2337c8589fb3855584cb8d15192b92c9 374 SUPERFAMILY SSF51679 11 359 7.59E-81 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10240 2337c8589fb3855584cb8d15192b92c9 374 Gene3D G3DSA:3.20.20.30 290 361 2.4E-90 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10240 2337c8589fb3855584cb8d15192b92c9 374 Gene3D G3DSA:3.20.20.30 16 254 2.4E-90 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10240 2337c8589fb3855584cb8d15192b92c9 374 PANTHER PTHR30011:SF20 1 360 4.2E-121 T 23-04-2016 DC74_RS10240 2337c8589fb3855584cb8d15192b92c9 374 PANTHER PTHR30011 1 360 4.2E-121 T 23-04-2016 DC74_RS24325 eaf6b4e0a0af429681aae473f21f11c9 470 PANTHER PTHR33885:SF3 25 427 1.2E-55 T 23-04-2016 DC74_RS24325 eaf6b4e0a0af429681aae473f21f11c9 470 Pfam PF04024 PspC domain 25 78 5.1E-15 T 23-04-2016 IPR007168 Phage shock protein, PspC, N-terminal DC74_RS24325 eaf6b4e0a0af429681aae473f21f11c9 470 PANTHER PTHR33885 25 427 1.2E-55 T 23-04-2016 DC74_RS03720 a59f388ed0ff79f927164ff14b03d7ce 123 Pfam PF13581 Histidine kinase-like ATPase domain 7 121 8.3E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS03720 a59f388ed0ff79f927164ff14b03d7ce 123 SUPERFAMILY SSF55874 31 122 1.38E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS03720 a59f388ed0ff79f927164ff14b03d7ce 123 Gene3D G3DSA:3.30.565.10 38 122 1.0E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS12505 21a41676e7b8eeeca3ea506ca84778da 371 Pfam PF05103 DivIVA protein 3 64 1.0E-13 T 23-04-2016 IPR007793 DivIVA family DC74_RS12505 21a41676e7b8eeeca3ea506ca84778da 371 PANTHER PTHR35794:SF2 1 70 1.8E-22 T 23-04-2016 DC74_RS12505 21a41676e7b8eeeca3ea506ca84778da 371 PANTHER PTHR35794:SF2 174 284 1.8E-22 T 23-04-2016 DC74_RS12505 21a41676e7b8eeeca3ea506ca84778da 371 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 38 1.8E-16 T 23-04-2016 IPR019933 DivIVA domain DC74_RS12505 21a41676e7b8eeeca3ea506ca84778da 371 PANTHER PTHR35794 1 70 1.8E-22 T 23-04-2016 DC74_RS12505 21a41676e7b8eeeca3ea506ca84778da 371 PANTHER PTHR35794 174 284 1.8E-22 T 23-04-2016 DC74_RS27215 7d7997921f33332c1d6270c7fd34802c 566 Pfam PF01642 Methylmalonyl-CoA mutase 29 558 3.8E-212 T 23-04-2016 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 DC74_RS27215 7d7997921f33332c1d6270c7fd34802c 566 PANTHER PTHR23408 440 563 0.0 T 23-04-2016 DC74_RS27215 7d7997921f33332c1d6270c7fd34802c 566 PANTHER PTHR23408 13 423 0.0 T 23-04-2016 DC74_RS27215 7d7997921f33332c1d6270c7fd34802c 566 SUPERFAMILY SSF51703 7 560 2.35E-191 T 23-04-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 DC74_RS27215 7d7997921f33332c1d6270c7fd34802c 566 Gene3D G3DSA:3.20.20.240 28 560 1.6E-214 T 23-04-2016 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 DC74_RS27215 7d7997921f33332c1d6270c7fd34802c 566 PANTHER PTHR23408:SF18 440 563 0.0 T 23-04-2016 DC74_RS27215 7d7997921f33332c1d6270c7fd34802c 566 PANTHER PTHR23408:SF18 13 423 0.0 T 23-04-2016 DC74_RS27215 7d7997921f33332c1d6270c7fd34802c 566 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 27 564 2.7E-198 T 23-04-2016 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 DC74_RS00550 a3457f6410e0aefcdb0a5113e6edd957 205 PANTHER PTHR30055 1 157 3.1E-19 T 23-04-2016 DC74_RS00550 a3457f6410e0aefcdb0a5113e6edd957 205 Pfam PF16859 Bacterial transcriptional repressor C-terminal 64 172 7.7E-23 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS00550 a3457f6410e0aefcdb0a5113e6edd957 205 SUPERFAMILY SSF46689 3 54 6.62E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00550 a3457f6410e0aefcdb0a5113e6edd957 205 Gene3D G3DSA:1.10.357.10 51 179 1.7E-24 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS00550 a3457f6410e0aefcdb0a5113e6edd957 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 1.1E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00550 a3457f6410e0aefcdb0a5113e6edd957 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 1.1E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00550 a3457f6410e0aefcdb0a5113e6edd957 205 PANTHER PTHR30055:SF66 1 157 3.1E-19 T 23-04-2016 DC74_RS00550 a3457f6410e0aefcdb0a5113e6edd957 205 SUPERFAMILY SSF48498 63 177 8.9E-19 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS00550 a3457f6410e0aefcdb0a5113e6edd957 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 50 3.2E-14 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00550 a3457f6410e0aefcdb0a5113e6edd957 205 Gene3D G3DSA:1.10.10.60 1 42 1.9E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07090 d7fe06628c9891751d0fbccd77915b06 252 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 226 1.0E-8 T 23-04-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS07090 d7fe06628c9891751d0fbccd77915b06 252 Hamap MF_00943 Maleate isomerase [maiA]. 4 250 46.819 T 23-04-2016 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 DC74_RS07090 d7fe06628c9891751d0fbccd77915b06 252 PIRSF PIRSF015736 2 251 5.5E-59 T 23-04-2016 IPR026286 Maleate isomerase/Arylmalonate decarboxylase DC74_RS07090 d7fe06628c9891751d0fbccd77915b06 252 PANTHER PTHR40267 1 252 1.1E-31 T 23-04-2016 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 23-04-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 Pfam PF00365 Phosphofructokinase 2 297 2.0E-103 T 23-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 2.0E-70 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 2.0E-70 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 2.0E-70 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 2.0E-70 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 2.0E-70 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 2.0E-70 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.0E-70 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.0E-70 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 2.0E-70 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 SUPERFAMILY SSF53784 1 333 4.97E-123 T 23-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 PIRSF PIRSF000532 1 340 1.2E-125 T 23-04-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 342 43.697 T 23-04-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 PANTHER PTHR13697 1 332 1.2E-136 T 23-04-2016 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 Gene3D G3DSA:3.40.50.450 1 211 2.2E-75 T 23-04-2016 DC74_RS12730 edeaa9576541138a2969ebaedf0d0ddc 342 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 322 2.9E-154 T 23-04-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS29910 4652554b4d490366a40c74d7aacdcb90 328 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 300 316 7.4E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS29910 4652554b4d490366a40c74d7aacdcb90 328 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 285 300 7.4E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS29910 4652554b4d490366a40c74d7aacdcb90 328 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 267 312 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS29910 4652554b4d490366a40c74d7aacdcb90 328 Gene3D G3DSA:1.10.10.60 212 255 1.7E-6 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS29910 4652554b4d490366a40c74d7aacdcb90 328 Gene3D G3DSA:1.10.10.60 266 318 9.3E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS29910 4652554b4d490366a40c74d7aacdcb90 328 Pfam PF14525 AraC-binding-like domain 21 195 3.1E-19 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS29910 4652554b4d490366a40c74d7aacdcb90 328 SUPERFAMILY SSF46689 266 317 2.06E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS29910 4652554b4d490366a40c74d7aacdcb90 328 Pfam PF12833 Helix-turn-helix domain 237 317 6.8E-19 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS29910 4652554b4d490366a40c74d7aacdcb90 328 SMART SM00342 231 316 5.8E-21 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS29910 4652554b4d490366a40c74d7aacdcb90 328 PANTHER PTHR11019:SF50 67 324 4.5E-26 T 23-04-2016 DC74_RS29910 4652554b4d490366a40c74d7aacdcb90 328 PANTHER PTHR11019 67 324 4.5E-26 T 23-04-2016 DC74_RS21540 c69c574c1d1cf34f88e65b8ca46a20ef 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 1.4E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21540 c69c574c1d1cf34f88e65b8ca46a20ef 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 1.4E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21540 c69c574c1d1cf34f88e65b8ca46a20ef 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 1.4E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21540 c69c574c1d1cf34f88e65b8ca46a20ef 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.4E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21540 c69c574c1d1cf34f88e65b8ca46a20ef 160 PANTHER PTHR33164 39 149 6.6E-23 T 23-04-2016 DC74_RS21540 c69c574c1d1cf34f88e65b8ca46a20ef 160 SMART SM00347 25 125 1.0E-19 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21540 c69c574c1d1cf34f88e65b8ca46a20ef 160 Pfam PF01047 MarR family 39 89 2.5E-12 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21540 c69c574c1d1cf34f88e65b8ca46a20ef 160 SUPERFAMILY SSF46785 18 142 1.34E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21540 c69c574c1d1cf34f88e65b8ca46a20ef 160 Gene3D G3DSA:1.10.10.10 13 138 5.1E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07765 a11657f7ec3ce2f964d74dec2b3dafd7 386 PANTHER PTHR10283:SF21 13 385 4.5E-32 T 23-04-2016 DC74_RS07765 a11657f7ec3ce2f964d74dec2b3dafd7 386 PANTHER PTHR10283 13 385 4.5E-32 T 23-04-2016 DC74_RS07765 a11657f7ec3ce2f964d74dec2b3dafd7 386 Pfam PF02040 Arsenical pump membrane protein 37 379 1.4E-23 T 23-04-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DC74_RS07765 a11657f7ec3ce2f964d74dec2b3dafd7 386 PRINTS PR00758 Arsenical pump membrane protein signature 326 351 5.9E-15 T 23-04-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DC74_RS07765 a11657f7ec3ce2f964d74dec2b3dafd7 386 PRINTS PR00758 Arsenical pump membrane protein signature 359 383 5.9E-15 T 23-04-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DC74_RS07765 a11657f7ec3ce2f964d74dec2b3dafd7 386 PRINTS PR00758 Arsenical pump membrane protein signature 81 105 5.9E-15 T 23-04-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DC74_RS07765 a11657f7ec3ce2f964d74dec2b3dafd7 386 PRINTS PR00758 Arsenical pump membrane protein signature 154 177 5.9E-15 T 23-04-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 Gene3D G3DSA:3.40.50.720 5 249 2.2E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 2.4E-55 T 23-04-2016 DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.01E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.01E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.01E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.01E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.01E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.01E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 PANTHER PTHR24322 12 138 5.4E-52 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 PANTHER PTHR24322 154 184 5.4E-52 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 SUPERFAMILY SSF51735 7 249 1.45E-77 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 5.04E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 5.04E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.04E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37225 a3bb45379a71153c5d2844697488ff18 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS33895 5854424b92c2844a4c5f0d3264e13d6a 279 SUPERFAMILY SSF52540 10 243 1.36E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33895 5854424b92c2844a4c5f0d3264e13d6a 279 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS33895 5854424b92c2844a4c5f0d3264e13d6a 279 PANTHER PTHR24220:SF447 11 250 4.0E-139 T 23-04-2016 DC74_RS33895 5854424b92c2844a4c5f0d3264e13d6a 279 SMART SM00382 34 221 2.5E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS33895 5854424b92c2844a4c5f0d3264e13d6a 279 Gene3D G3DSA:3.40.50.300 9 245 5.9E-86 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33895 5854424b92c2844a4c5f0d3264e13d6a 279 Pfam PF00005 ABC transporter 25 173 3.5E-35 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS33895 5854424b92c2844a4c5f0d3264e13d6a 279 PANTHER PTHR24220 11 250 4.0E-139 T 23-04-2016 DC74_RS33895 5854424b92c2844a4c5f0d3264e13d6a 279 PIRSF PIRSF039085 7 249 1.5E-114 T 23-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 DC74_RS12185 4c9c883ab4b259ce954a4d81b58c73e9 382 PANTHER PTHR24421 34 379 2.5E-55 T 23-04-2016 DC74_RS12185 4c9c883ab4b259ce954a4d81b58c73e9 382 SUPERFAMILY SSF55874 267 376 1.48E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS12185 4c9c883ab4b259ce954a4d81b58c73e9 382 PANTHER PTHR24421:SF26 34 379 2.5E-55 T 23-04-2016 DC74_RS12185 4c9c883ab4b259ce954a4d81b58c73e9 382 Gene3D G3DSA:3.30.565.10 282 377 4.4E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS12185 4c9c883ab4b259ce954a4d81b58c73e9 382 Pfam PF07730 Histidine kinase 176 240 6.6E-13 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS12185 4c9c883ab4b259ce954a4d81b58c73e9 382 SMART SM00387 282 378 4.9E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33200 88ee0793ed197560ce25f3ef31603e94 309 PRINTS PR00164 ABC-2 type transport system membrane protein signature 75 96 5.1E-6 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS33200 88ee0793ed197560ce25f3ef31603e94 309 PRINTS PR00164 ABC-2 type transport system membrane protein signature 106 128 5.1E-6 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS33200 88ee0793ed197560ce25f3ef31603e94 309 PRINTS PR00164 ABC-2 type transport system membrane protein signature 182 206 5.1E-6 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS33200 88ee0793ed197560ce25f3ef31603e94 309 PRINTS PR00164 ABC-2 type transport system membrane protein signature 219 238 5.1E-6 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS33200 88ee0793ed197560ce25f3ef31603e94 309 Pfam PF01061 ABC-2 type transporter 65 267 5.6E-16 T 23-04-2016 IPR013525 ABC-2 type transporter GO:0016020 DC74_RS33200 88ee0793ed197560ce25f3ef31603e94 309 PANTHER PTHR30294:SF14 2 308 4.0E-70 T 23-04-2016 DC74_RS33200 88ee0793ed197560ce25f3ef31603e94 309 PANTHER PTHR30294 2 308 4.0E-70 T 23-04-2016 DC74_RS12585 e2ed0a2103b39b0348278a90d3be4ce1 186 SUPERFAMILY SSF53056 23 184 2.35E-34 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS12585 e2ed0a2103b39b0348278a90d3be4ce1 186 PANTHER PTHR11002:SF9 26 183 5.3E-50 T 23-04-2016 DC74_RS12585 e2ed0a2103b39b0348278a90d3be4ce1 186 PANTHER PTHR11002 26 183 5.3E-50 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS12585 e2ed0a2103b39b0348278a90d3be4ce1 186 SMART SM00947 45 183 4.1E-23 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS12585 e2ed0a2103b39b0348278a90d3be4ce1 186 Gene3D G3DSA:3.40.1050.10 25 183 4.8E-33 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS12585 e2ed0a2103b39b0348278a90d3be4ce1 186 Pfam PF00484 Carbonic anhydrase 53 125 3.7E-11 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS05800 07bf022717349898b405bbe12b2f427c 75 Gene3D G3DSA:1.10.1200.10 1 73 2.5E-17 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05800 07bf022717349898b405bbe12b2f427c 75 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 28 69 0.004 T 23-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 DC74_RS05800 07bf022717349898b405bbe12b2f427c 75 SUPERFAMILY SSF47336 1 73 3.66E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05800 07bf022717349898b405bbe12b2f427c 75 Pfam PF00550 Phosphopantetheine attachment site 1 68 7.0E-12 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS05800 07bf022717349898b405bbe12b2f427c 75 ProSitePatterns PS00012 Phosphopantetheine attachment site. 25 40 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS34020 70e45e304d84c8c53f137e8303e8f4d6 459 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 307 330 - T 23-04-2016 IPR018107 Sodium:dicarboxylate symporter, conserved site Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS34020 70e45e304d84c8c53f137e8303e8f4d6 459 PANTHER PTHR11958 14 453 2.5E-155 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS34020 70e45e304d84c8c53f137e8303e8f4d6 459 Pfam PF00375 Sodium:dicarboxylate symporter family 20 413 5.7E-106 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS34020 70e45e304d84c8c53f137e8303e8f4d6 459 SUPERFAMILY SSF118215 20 414 3.4E-107 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS34020 70e45e304d84c8c53f137e8303e8f4d6 459 PANTHER PTHR11958:SF49 14 453 2.5E-155 T 23-04-2016 DC74_RS34020 70e45e304d84c8c53f137e8303e8f4d6 459 Gene3D G3DSA:1.10.3860.10 14 418 7.3E-105 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS34020 70e45e304d84c8c53f137e8303e8f4d6 459 PRINTS PR00173 Glutamate-aspartate symporter signature 55 75 7.9E-25 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS34020 70e45e304d84c8c53f137e8303e8f4d6 459 PRINTS PR00173 Glutamate-aspartate symporter signature 85 110 7.9E-25 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS34020 70e45e304d84c8c53f137e8303e8f4d6 459 PRINTS PR00173 Glutamate-aspartate symporter signature 339 358 7.9E-25 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS34020 70e45e304d84c8c53f137e8303e8f4d6 459 PRINTS PR00173 Glutamate-aspartate symporter signature 14 34 7.9E-25 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS34020 70e45e304d84c8c53f137e8303e8f4d6 459 PRINTS PR00173 Glutamate-aspartate symporter signature 304 330 7.9E-25 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 SUPERFAMILY SSF47648 1 69 2.49E-19 T 23-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 336 407 3.7E-23 T 23-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 23-04-2016 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 407 1.7E-167 T 23-04-2016 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|UniPathway: UPA00578 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 PANTHER PTHR10515:SF0 1 425 6.3E-193 T 23-04-2016 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 PANTHER PTHR10515 1 425 6.3E-193 T 23-04-2016 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 SUPERFAMILY SSF52418 69 316 1.07E-82 T 23-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 Gene3D G3DSA:3.40.1030.10 70 317 2.3E-110 T 23-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 66 6.9E-19 T 23-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 Gene3D G3DSA:3.90.1170.30 318 410 3.9E-31 T 23-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 Pfam PF00591 Glycosyl transferase family, a/b domain 77 287 5.5E-36 T 23-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 SMART SM00941 334 408 3.9E-33 T 23-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 SUPERFAMILY SSF54680 321 424 7.32E-26 T 23-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 PIRSF PIRSF000478 1 424 3.4E-151 T 23-04-2016 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 DC74_RS24945 a093fac7ce18d017f6e24821b3c0b3ab 425 Gene3D G3DSA:1.20.970.10 1 67 3.3E-27 T 23-04-2016 DC74_RS39780 cdd07d4c962fa1348c1318ed9d740512 484 Gene3D G3DSA:3.50.50.60 422 481 5.8E-64 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39780 cdd07d4c962fa1348c1318ed9d740512 484 Gene3D G3DSA:3.50.50.60 10 280 5.8E-64 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39780 cdd07d4c962fa1348c1318ed9d740512 484 SUPERFAMILY SSF56425 296 408 5.23E-20 T 23-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain DC74_RS39780 cdd07d4c962fa1348c1318ed9d740512 484 Gene3D G3DSA:3.90.700.10 296 406 3.2E-18 T 23-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain DC74_RS39780 cdd07d4c962fa1348c1318ed9d740512 484 Pfam PF00890 FAD binding domain 17 463 4.2E-47 T 23-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain DC74_RS39780 cdd07d4c962fa1348c1318ed9d740512 484 PANTHER PTHR11632 152 481 6.0E-68 T 23-04-2016 DC74_RS39780 cdd07d4c962fa1348c1318ed9d740512 484 PANTHER PTHR11632 17 126 6.0E-68 T 23-04-2016 DC74_RS39780 cdd07d4c962fa1348c1318ed9d740512 484 PANTHER PTHR11632:SF48 152 481 6.0E-68 T 23-04-2016 DC74_RS39780 cdd07d4c962fa1348c1318ed9d740512 484 PANTHER PTHR11632:SF48 17 126 6.0E-68 T 23-04-2016 DC74_RS39780 cdd07d4c962fa1348c1318ed9d740512 484 SUPERFAMILY SSF51905 425 481 7.65E-40 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39780 cdd07d4c962fa1348c1318ed9d740512 484 SUPERFAMILY SSF51905 182 297 7.65E-40 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39780 cdd07d4c962fa1348c1318ed9d740512 484 SUPERFAMILY SSF51905 5 150 7.65E-40 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28795 1e67318151319cef9765de8b3fe760fd 179 Gene3D G3DSA:2.60.120.10 44 161 1.2E-16 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS28795 1e67318151319cef9765de8b3fe760fd 179 SUPERFAMILY SSF51182 20 164 1.62E-28 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS28795 1e67318151319cef9765de8b3fe760fd 179 PANTHER PTHR12918 44 165 1.4E-27 T 23-04-2016 DC74_RS28795 1e67318151319cef9765de8b3fe760fd 179 Pfam PF05995 Cysteine dioxygenase type I 22 163 2.0E-44 T 23-04-2016 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|UniPathway: UPA00012 DC74_RS03115 ba9f97ebabadb537f4206ab93810b9ce 416 Gene3D G3DSA:3.40.50.200 88 411 2.1E-63 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS03115 ba9f97ebabadb537f4206ab93810b9ce 416 PANTHER PTHR14218 86 409 5.6E-21 T 23-04-2016 DC74_RS03115 ba9f97ebabadb537f4206ab93810b9ce 416 SUPERFAMILY SSF52743 88 414 7.33E-42 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS03115 ba9f97ebabadb537f4206ab93810b9ce 416 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 341 351 - T 23-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site DC74_RS03115 ba9f97ebabadb537f4206ab93810b9ce 416 PRINTS PR00723 Subtilisin serine protease family (S8) signature 105 124 1.0E-5 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS03115 ba9f97ebabadb537f4206ab93810b9ce 416 PRINTS PR00723 Subtilisin serine protease family (S8) signature 340 356 1.0E-5 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS03115 ba9f97ebabadb537f4206ab93810b9ce 416 PANTHER PTHR14218:SF15 86 409 5.6E-21 T 23-04-2016 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 Gene3D G3DSA:1.10.287.130 256 317 1.0E-14 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 SUPERFAMILY SSF47384 249 331 3.92E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 SMART SM00388 264 331 9.3E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 PANTHER PTHR24423 134 145 1.3E-73 T 23-04-2016 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 PANTHER PTHR24423 198 501 1.3E-73 T 23-04-2016 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 SMART SM00304 204 256 7.8E-16 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 SUPERFAMILY SSF55874 320 484 1.44E-36 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 Pfam PF00512 His Kinase A (phospho-acceptor) domain 266 331 4.8E-14 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 Gene3D G3DSA:3.30.565.10 318 485 4.7E-40 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 SMART SM00387 371 483 7.3E-34 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 372 482 1.6E-21 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 SUPERFAMILY SSF158472 204 254 1.96E-10 T 23-04-2016 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 Pfam PF00672 HAMP domain 189 252 1.5E-15 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 461 8.2E-17 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 437 8.2E-17 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 423 8.2E-17 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS32890 edb8f06387ec950012e5dd12795db6aa 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 480 8.2E-17 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS29810 f9da55d53ac0639a827b00ad37a4caee 267 Pfam PF14257 Domain of unknown function (DUF4349) 1 200 1.2E-58 T 23-04-2016 IPR025645 Domain of unknown function DUF4349 DC74_RS33520 c7ec0f5f8e538bc3a8ab5b282ed3035a 549 PANTHER PTHR10909 28 457 2.4E-194 T 23-04-2016 DC74_RS33520 c7ec0f5f8e538bc3a8ab5b282ed3035a 549 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 396 415 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS33520 c7ec0f5f8e538bc3a8ab5b282ed3035a 549 SUPERFAMILY SSF56645 57 290 3.53E-41 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS33520 c7ec0f5f8e538bc3a8ab5b282ed3035a 549 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 281 437 2.3E-27 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS33520 c7ec0f5f8e538bc3a8ab5b282ed3035a 549 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 177 271 9.3E-19 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS33520 c7ec0f5f8e538bc3a8ab5b282ed3035a 549 Gene3D G3DSA:2.40.110.10 177 268 8.5E-24 T 23-04-2016 DC74_RS33520 c7ec0f5f8e538bc3a8ab5b282ed3035a 549 PANTHER PTHR10909:SF289 28 457 2.4E-194 T 23-04-2016 DC74_RS33520 c7ec0f5f8e538bc3a8ab5b282ed3035a 549 Gene3D G3DSA:1.20.140.10 269 442 9.0E-38 T 23-04-2016 DC74_RS33520 c7ec0f5f8e538bc3a8ab5b282ed3035a 549 SUPERFAMILY SSF47203 286 440 7.73E-38 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS32135 dba4bc71f4e45a967a17a2187968f13f 603 Pfam PF00664 ABC transporter transmembrane region 40 302 5.5E-29 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS32135 dba4bc71f4e45a967a17a2187968f13f 603 PANTHER PTHR24221:SF161 9 595 5.6E-141 T 23-04-2016 DC74_RS32135 dba4bc71f4e45a967a17a2187968f13f 603 SUPERFAMILY SSF52540 346 586 3.38E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32135 dba4bc71f4e45a967a17a2187968f13f 603 Gene3D G3DSA:1.20.1560.10 24 332 7.8E-54 T 23-04-2016 DC74_RS32135 dba4bc71f4e45a967a17a2187968f13f 603 Gene3D G3DSA:3.40.50.300 350 579 7.0E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32135 dba4bc71f4e45a967a17a2187968f13f 603 SUPERFAMILY SSF90123 24 331 2.09E-54 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS32135 dba4bc71f4e45a967a17a2187968f13f 603 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS32135 dba4bc71f4e45a967a17a2187968f13f 603 PANTHER PTHR24221 9 595 5.6E-141 T 23-04-2016 DC74_RS32135 dba4bc71f4e45a967a17a2187968f13f 603 Pfam PF00005 ABC transporter 367 515 6.8E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS32135 dba4bc71f4e45a967a17a2187968f13f 603 SMART SM00382 376 562 9.1E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS11880 b2080bbb6828156a625b7df097c019c3 338 SUPERFAMILY SSF50129 1 173 3.04E-52 T 23-04-2016 IPR011032 GroES-like DC74_RS11880 b2080bbb6828156a625b7df097c019c3 338 SUPERFAMILY SSF51735 140 297 5.92E-27 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11880 b2080bbb6828156a625b7df097c019c3 338 Gene3D G3DSA:3.40.50.720 166 281 1.7E-27 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11880 b2080bbb6828156a625b7df097c019c3 338 PANTHER PTHR11695 15 336 5.5E-94 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS11880 b2080bbb6828156a625b7df097c019c3 338 Pfam PF00107 Zinc-binding dehydrogenase 175 295 4.1E-16 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS11880 b2080bbb6828156a625b7df097c019c3 338 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS11880 b2080bbb6828156a625b7df097c019c3 338 PANTHER PTHR11695:SF429 15 336 5.5E-94 T 23-04-2016 DC74_RS11880 b2080bbb6828156a625b7df097c019c3 338 Gene3D G3DSA:3.90.180.10 1 165 4.2E-52 T 23-04-2016 IPR011032 GroES-like DC74_RS11880 b2080bbb6828156a625b7df097c019c3 338 SMART SM00829 10 333 6.2E-4 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS11880 b2080bbb6828156a625b7df097c019c3 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 132 1.4E-32 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS02310 c7e8d0afc025a4a142134acfa2513415 360 SUPERFAMILY SSF51905 4 165 3.89E-44 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02310 c7e8d0afc025a4a142134acfa2513415 360 SUPERFAMILY SSF51905 264 349 3.89E-44 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02310 c7e8d0afc025a4a142134acfa2513415 360 PANTHER PTHR13789 2 348 3.3E-91 T 23-04-2016 DC74_RS02310 c7e8d0afc025a4a142134acfa2513415 360 Gene3D G3DSA:3.50.50.60 3 171 3.1E-30 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02310 c7e8d0afc025a4a142134acfa2513415 360 Gene3D G3DSA:3.50.50.60 265 347 3.1E-30 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS02310 c7e8d0afc025a4a142134acfa2513415 360 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 3.1E-15 T 23-04-2016 DC74_RS02310 c7e8d0afc025a4a142134acfa2513415 360 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 3.1E-15 T 23-04-2016 DC74_RS02310 c7e8d0afc025a4a142134acfa2513415 360 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 3.1E-15 T 23-04-2016 DC74_RS02310 c7e8d0afc025a4a142134acfa2513415 360 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 3.1E-15 T 23-04-2016 DC74_RS02310 c7e8d0afc025a4a142134acfa2513415 360 PANTHER PTHR13789:SF251 2 348 3.3E-91 T 23-04-2016 DC74_RS02310 c7e8d0afc025a4a142134acfa2513415 360 Pfam PF01494 FAD binding domain 5 334 7.6E-21 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS38160 bf65f2a1a0769cdaa7c897960860c031 392 Pfam PF10067 Predicted membrane protein (DUF2306) 75 205 5.7E-12 T 23-04-2016 IPR018750 Protein of unknown function DUF2306, membrane DC74_RS14660 a97dd46349765ff0f10e7352c1db3501 265 SUPERFAMILY SSF53335 6 225 3.52E-60 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14660 a97dd46349765ff0f10e7352c1db3501 265 Pfam PF04072 Leucine carboxyl methyltransferase 16 169 4.7E-17 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS14660 a97dd46349765ff0f10e7352c1db3501 265 PANTHER PTHR13600 4 189 8.3E-55 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS14660 a97dd46349765ff0f10e7352c1db3501 265 PIRSF PIRSF028177 1 258 9.9E-74 T 23-04-2016 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.-|UniPathway: UPA00174 DC74_RS14660 a97dd46349765ff0f10e7352c1db3501 265 Gene3D G3DSA:3.40.50.150 5 183 2.9E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14660 a97dd46349765ff0f10e7352c1db3501 265 PANTHER PTHR13600:SF19 4 189 8.3E-55 T 23-04-2016 DC74_RS28580 3e62927f1380fcd70cfdb501b9c410fe 459 Pfam PF05193 Peptidase M16 inactive domain 199 380 5.7E-43 T 23-04-2016 IPR007863 Peptidase M16, C-terminal DC74_RS28580 3e62927f1380fcd70cfdb501b9c410fe 459 Pfam PF00675 Insulinase (Peptidase family M16) 45 192 5.3E-36 T 23-04-2016 IPR011765 Peptidase M16, N-terminal DC74_RS28580 3e62927f1380fcd70cfdb501b9c410fe 459 Gene3D G3DSA:3.30.830.10 35 240 4.2E-57 T 23-04-2016 IPR011237 Peptidase M16 domain GO:0046872 DC74_RS28580 3e62927f1380fcd70cfdb501b9c410fe 459 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 66 89 - T 23-04-2016 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 DC74_RS28580 3e62927f1380fcd70cfdb501b9c410fe 459 Gene3D G3DSA:3.30.830.10 271 448 5.8E-57 T 23-04-2016 IPR011237 Peptidase M16 domain GO:0046872 DC74_RS28580 3e62927f1380fcd70cfdb501b9c410fe 459 SUPERFAMILY SSF63411 265 448 3.83E-47 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 DC74_RS28580 3e62927f1380fcd70cfdb501b9c410fe 459 PANTHER PTHR11851 35 456 5.9E-128 T 23-04-2016 DC74_RS28580 3e62927f1380fcd70cfdb501b9c410fe 459 SUPERFAMILY SSF63411 34 238 1.04E-59 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 DC74_RS18785 dbfa601289d46bc945efd8989c45640a 176 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 25.132 T 23-04-2016 IPR022973 Ribosomal protein L10 DC74_RS18785 dbfa601289d46bc945efd8989c45640a 176 Pfam PF00466 Ribosomal protein L10 2 98 2.1E-27 T 23-04-2016 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 DC74_RS18785 dbfa601289d46bc945efd8989c45640a 176 PANTHER PTHR11560 1 176 3.7E-52 T 23-04-2016 DC74_RS18785 dbfa601289d46bc945efd8989c45640a 176 SUPERFAMILY SSF160369 1 169 1.83E-51 T 23-04-2016 DC74_RS39910 4b3130d392b64552012aeb14cba0de5a 140 Pfam PF01042 Endoribonuclease L-PSP 23 134 9.9E-19 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS39910 4b3130d392b64552012aeb14cba0de5a 140 PANTHER PTHR11803 17 140 3.7E-25 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS39910 4b3130d392b64552012aeb14cba0de5a 140 SUPERFAMILY SSF55298 22 137 2.67E-28 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS39910 4b3130d392b64552012aeb14cba0de5a 140 Gene3D G3DSA:3.30.1330.40 24 137 1.1E-31 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS04140 18de846626645564b327070dc5a38bb2 398 Gene3D G3DSA:2.30.38.10 160 239 4.2E-19 T 23-04-2016 DC74_RS04140 18de846626645564b327070dc5a38bb2 398 PANTHER PTHR24095:SF173 1 287 9.1E-74 T 23-04-2016 DC74_RS04140 18de846626645564b327070dc5a38bb2 398 Gene3D G3DSA:3.30.300.30 243 287 2.8E-10 T 23-04-2016 DC74_RS04140 18de846626645564b327070dc5a38bb2 398 Pfam PF00501 AMP-binding enzyme 3 249 1.2E-37 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS04140 18de846626645564b327070dc5a38bb2 398 Gene3D G3DSA:1.10.630.10 294 369 7.5E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04140 18de846626645564b327070dc5a38bb2 398 SUPERFAMILY SSF56801 1 287 3.27E-65 T 23-04-2016 DC74_RS04140 18de846626645564b327070dc5a38bb2 398 Gene3D G3DSA:3.40.50.980 8 159 8.1E-26 T 23-04-2016 DC74_RS04140 18de846626645564b327070dc5a38bb2 398 PANTHER PTHR24095 1 287 9.1E-74 T 23-04-2016 DC74_RS28460 5a74a329984e64d18b3748d6ad2a7f2d 317 Pfam PF01687 Riboflavin kinase 188 309 1.5E-31 T 23-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 DC74_RS28460 5a74a329984e64d18b3748d6ad2a7f2d 317 Gene3D G3DSA:2.40.30.30 184 313 1.2E-42 T 23-04-2016 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 DC74_RS28460 5a74a329984e64d18b3748d6ad2a7f2d 317 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 310 3.1E-66 T 23-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 DC74_RS28460 5a74a329984e64d18b3748d6ad2a7f2d 317 PANTHER PTHR22749 1 313 1.6E-119 T 23-04-2016 IPR023468 Riboflavin kinase KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|UniPathway: UPA00276 DC74_RS28460 5a74a329984e64d18b3748d6ad2a7f2d 317 PIRSF PIRSF004491 2 316 9.9E-93 T 23-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 DC74_RS28460 5a74a329984e64d18b3748d6ad2a7f2d 317 Pfam PF06574 FAD synthetase 15 158 1.0E-48 T 23-04-2016 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 DC74_RS28460 5a74a329984e64d18b3748d6ad2a7f2d 317 Gene3D G3DSA:3.40.50.620 3 183 2.8E-61 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS28460 5a74a329984e64d18b3748d6ad2a7f2d 317 SUPERFAMILY SSF52374 16 179 2.97E-32 T 23-04-2016 DC74_RS28460 5a74a329984e64d18b3748d6ad2a7f2d 317 SMART SM00904 187 312 1.4E-44 T 23-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 DC74_RS28460 5a74a329984e64d18b3748d6ad2a7f2d 317 PANTHER PTHR22749:SF0 1 313 1.6E-119 T 23-04-2016 DC74_RS28460 5a74a329984e64d18b3748d6ad2a7f2d 317 SUPERFAMILY SSF82114 178 312 4.14E-41 T 23-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 DC74_RS09020 233163004aa476e5f1fb0f55d32c9ac6 551 Pfam PF01425 Amidase 81 515 1.6E-106 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS09020 233163004aa476e5f1fb0f55d32c9ac6 551 SUPERFAMILY SSF75304 59 531 3.92E-114 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS09020 233163004aa476e5f1fb0f55d32c9ac6 551 PANTHER PTHR11895 59 532 3.0E-187 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS09020 233163004aa476e5f1fb0f55d32c9ac6 551 Gene3D G3DSA:3.90.1300.10 58 533 1.2E-137 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS09020 233163004aa476e5f1fb0f55d32c9ac6 551 PANTHER PTHR11895:SF8 59 532 3.0E-187 T 23-04-2016 DC74_RS07345 6325fe25850945614ce2fd77649b1cb7 503 PANTHER PTHR33744:SF3 1 500 2.0E-40 T 23-04-2016 DC74_RS07345 6325fe25850945614ce2fd77649b1cb7 503 Pfam PF13556 PucR C-terminal helix-turn-helix domain 444 501 2.1E-20 T 23-04-2016 IPR025736 PucR C-terminal helix-turn-helix domain DC74_RS07345 6325fe25850945614ce2fd77649b1cb7 503 PANTHER PTHR33744 1 500 2.0E-40 T 23-04-2016 DC74_RS07345 6325fe25850945614ce2fd77649b1cb7 503 Pfam PF07905 Purine catabolism regulatory protein-like family 5 122 1.1E-19 T 23-04-2016 IPR012914 Purine catabolism PurC-like domain DC74_RS23425 77f2a7e9acc9f13ca248239cb27b459a 337 SMART SM00829 10 335 7.8E-11 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS23425 77f2a7e9acc9f13ca248239cb27b459a 337 PANTHER PTHR11695:SF605 15 337 2.7E-74 T 23-04-2016 DC74_RS23425 77f2a7e9acc9f13ca248239cb27b459a 337 SUPERFAMILY SSF50129 1 137 3.62E-27 T 23-04-2016 IPR011032 GroES-like DC74_RS23425 77f2a7e9acc9f13ca248239cb27b459a 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 92 2.5E-5 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS23425 77f2a7e9acc9f13ca248239cb27b459a 337 SUPERFAMILY SSF51735 117 271 5.14E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS23425 77f2a7e9acc9f13ca248239cb27b459a 337 Gene3D G3DSA:3.40.50.720 149 272 5.8E-26 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS23425 77f2a7e9acc9f13ca248239cb27b459a 337 Pfam PF00107 Zinc-binding dehydrogenase 155 271 2.6E-19 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS23425 77f2a7e9acc9f13ca248239cb27b459a 337 Gene3D G3DSA:3.90.180.10 1 148 9.7E-27 T 23-04-2016 IPR011032 GroES-like DC74_RS23425 77f2a7e9acc9f13ca248239cb27b459a 337 PANTHER PTHR11695 15 337 2.7E-74 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 11 477 2.2E-236 T 23-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 359 1.9E-63 T 23-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 Gene3D G3DSA:1.10.1140.10 362 477 6.9E-45 T 23-04-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 Hamap MF_01347 ATP synthase subunit beta [atpB]. 9 477 54.255 T 23-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 Gene3D G3DSA:2.40.10.170 5 89 6.3E-31 T 23-04-2016 DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 PANTHER PTHR15184:SF8 1 477 2.7E-299 T 23-04-2016 DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 PANTHER PTHR15184 1 477 2.7E-299 T 23-04-2016 DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 SMART SM00382 158 421 0.0016 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 350 359 - T 23-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 SUPERFAMILY SSF50615 11 89 7.32E-26 T 23-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 Gene3D G3DSA:3.40.50.300 92 361 1.7E-102 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 SUPERFAMILY SSF47917 362 477 1.02E-45 T 23-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 14 88 6.3E-23 T 23-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS26945 690adbe54b9324ccf4a7f8437b6b8f40 480 SUPERFAMILY SSF52540 92 364 1.67E-85 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39065 ec27168f6360076130e287be02cbb4cd 370 PANTHER PTHR22604 2 277 3.3E-80 T 23-04-2016 DC74_RS39065 ec27168f6360076130e287be02cbb4cd 370 SUPERFAMILY SSF51735 2 153 8.39E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39065 ec27168f6360076130e287be02cbb4cd 370 PANTHER PTHR22604 295 366 3.3E-80 T 23-04-2016 DC74_RS39065 ec27168f6360076130e287be02cbb4cd 370 PANTHER PTHR22604:SF120 2 277 3.3E-80 T 23-04-2016 DC74_RS39065 ec27168f6360076130e287be02cbb4cd 370 Gene3D G3DSA:3.40.50.720 2 140 2.7E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39065 ec27168f6360076130e287be02cbb4cd 370 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 122 1.5E-23 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 DC74_RS39065 ec27168f6360076130e287be02cbb4cd 370 Gene3D G3DSA:3.30.360.10 141 260 1.6E-53 T 23-04-2016 DC74_RS39065 ec27168f6360076130e287be02cbb4cd 370 Gene3D G3DSA:3.30.360.10 298 357 1.6E-53 T 23-04-2016 DC74_RS39065 ec27168f6360076130e287be02cbb4cd 370 SUPERFAMILY SSF55347 129 271 7.03E-33 T 23-04-2016 DC74_RS39065 ec27168f6360076130e287be02cbb4cd 370 PANTHER PTHR22604:SF120 295 366 3.3E-80 T 23-04-2016 DC74_RS39065 ec27168f6360076130e287be02cbb4cd 370 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 136 239 7.6E-13 T 23-04-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 DC74_RS21240 32671c9649193f03387a15ff316ae3f7 327 Gene3D G3DSA:3.40.50.300 11 236 7.9E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21240 32671c9649193f03387a15ff316ae3f7 327 PANTHER PTHR24220 303 313 5.9E-95 T 23-04-2016 DC74_RS21240 32671c9649193f03387a15ff316ae3f7 327 PANTHER PTHR24220 17 238 5.9E-95 T 23-04-2016 DC74_RS21240 32671c9649193f03387a15ff316ae3f7 327 SUPERFAMILY SSF52540 16 236 8.7E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21240 32671c9649193f03387a15ff316ae3f7 327 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS21240 32671c9649193f03387a15ff316ae3f7 327 SMART SM00382 40 223 6.1E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS21240 32671c9649193f03387a15ff316ae3f7 327 Pfam PF00005 ABC transporter 31 174 3.8E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS21240 32671c9649193f03387a15ff316ae3f7 327 PANTHER PTHR24220:SF0 303 313 5.9E-95 T 23-04-2016 DC74_RS21240 32671c9649193f03387a15ff316ae3f7 327 PANTHER PTHR24220:SF0 17 238 5.9E-95 T 23-04-2016 DC74_RS21240 32671c9649193f03387a15ff316ae3f7 327 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 23 315 6.2E-97 T 23-04-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 KEGG: 00920+3.6.3.- DC74_RS10985 2489b9264273977c73ce719e4208b971 193 Gene3D G3DSA:1.10.530.10 54 138 3.0E-36 T 23-04-2016 DC74_RS10985 2489b9264273977c73ce719e4208b971 193 Gene3D G3DSA:3.10.350.10 142 192 1.5E-9 T 23-04-2016 IPR018392 LysM domain DC74_RS10985 2489b9264273977c73ce719e4208b971 193 SUPERFAMILY SSF54106 143 192 7.85E-6 T 23-04-2016 IPR018392 LysM domain DC74_RS10985 2489b9264273977c73ce719e4208b971 193 SUPERFAMILY SSF53955 58 138 1.23E-30 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS10985 2489b9264273977c73ce719e4208b971 193 Pfam PF01476 LysM domain 145 190 1.1E-4 T 23-04-2016 IPR018392 LysM domain DC74_RS10985 2489b9264273977c73ce719e4208b971 193 Pfam PF06737 Transglycosylase-like domain 59 132 3.0E-30 T 23-04-2016 IPR010618 Transglycosylase-like DC74_RS26795 40c99cb99a8106de2fbe93ac9cd36e61 154 PANTHER PTHR33164 14 152 1.9E-50 T 23-04-2016 DC74_RS26795 40c99cb99a8106de2fbe93ac9cd36e61 154 Pfam PF12802 MarR family 39 101 2.0E-9 T 23-04-2016 DC74_RS26795 40c99cb99a8106de2fbe93ac9cd36e61 154 SMART SM00347 33 137 1.5E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS26795 40c99cb99a8106de2fbe93ac9cd36e61 154 PANTHER PTHR33164:SF12 14 152 1.9E-50 T 23-04-2016 DC74_RS26795 40c99cb99a8106de2fbe93ac9cd36e61 154 Gene3D G3DSA:1.10.10.10 8 151 8.9E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26795 40c99cb99a8106de2fbe93ac9cd36e61 154 SUPERFAMILY SSF46785 14 150 1.48E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05120 907c518b27b0919d6137c33d1175498b 209 PANTHER PTHR34573:SF2 27 209 4.1E-45 T 23-04-2016 DC74_RS05120 907c518b27b0919d6137c33d1175498b 209 PANTHER PTHR34573 27 209 4.1E-45 T 23-04-2016 DC74_RS05120 907c518b27b0919d6137c33d1175498b 209 SMART SM00756 23 164 1.1E-52 T 23-04-2016 IPR012932 Vitamin K epoxide reductase DC74_RS05120 907c518b27b0919d6137c33d1175498b 209 Pfam PF07884 Vitamin K epoxide reductase family 28 160 1.3E-28 T 23-04-2016 IPR012932 Vitamin K epoxide reductase DC74_RS00335 338890ee6676a402ce8b04d0b1863a8f 348 Pfam PF04909 Amidohydrolase 5 334 1.4E-39 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS00335 338890ee6676a402ce8b04d0b1863a8f 348 Gene3D G3DSA:3.20.20.140 5 336 4.7E-73 T 23-04-2016 DC74_RS00335 338890ee6676a402ce8b04d0b1863a8f 348 SUPERFAMILY SSF51556 5 334 1.29E-70 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS00335 338890ee6676a402ce8b04d0b1863a8f 348 PANTHER PTHR21240 1 346 2.8E-66 T 23-04-2016 DC74_RS00335 338890ee6676a402ce8b04d0b1863a8f 348 PANTHER PTHR21240:SF3 1 346 2.8E-66 T 23-04-2016 IPR032465 Amino-carboxymuconate-semialdehyde decarboxylase GO:0001760|GO:0006568|GO:1904984 KEGG: 00380+4.1.1.45|MetaCyc: PWY-5647|MetaCyc: PWY-5652|MetaCyc: PWY-5654|UniPathway: UPA00270 DC74_RS10790 10aee75c892d79e1971b371d6fa4d976 390 PANTHER PTHR10108 283 288 5.2E-32 T 23-04-2016 DC74_RS10790 10aee75c892d79e1971b371d6fa4d976 390 PANTHER PTHR10108 18 163 5.2E-32 T 23-04-2016 DC74_RS10790 10aee75c892d79e1971b371d6fa4d976 390 SUPERFAMILY SSF53335 18 162 1.02E-39 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS10790 10aee75c892d79e1971b371d6fa4d976 390 Gene3D G3DSA:3.90.79.10 224 340 4.6E-21 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS10790 10aee75c892d79e1971b371d6fa4d976 390 Pfam PF08241 Methyltransferase domain 61 154 1.2E-22 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS10790 10aee75c892d79e1971b371d6fa4d976 390 ProSitePatterns PS00893 Nudix box signature. 257 278 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS10790 10aee75c892d79e1971b371d6fa4d976 390 Gene3D G3DSA:3.40.50.150 20 167 2.2E-35 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS10790 10aee75c892d79e1971b371d6fa4d976 390 PANTHER PTHR10108:SF721 283 288 5.2E-32 T 23-04-2016 DC74_RS10790 10aee75c892d79e1971b371d6fa4d976 390 PANTHER PTHR10108:SF721 18 163 5.2E-32 T 23-04-2016 DC74_RS10790 10aee75c892d79e1971b371d6fa4d976 390 Pfam PF00293 NUDIX domain 227 340 2.3E-13 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS10790 10aee75c892d79e1971b371d6fa4d976 390 SUPERFAMILY SSF55811 200 345 2.71E-21 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS31355 df0d235ce15b6220070ea074891795a8 467 Pfam PF00860 Permease family 27 408 2.3E-94 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS31355 df0d235ce15b6220070ea074891795a8 467 TIGRFAM TIGR03173 pbuX: xanthine permease 31 442 9.3E-144 T 23-04-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 DC74_RS31355 df0d235ce15b6220070ea074891795a8 467 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 26 439 1.3E-106 T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 DC74_RS31355 df0d235ce15b6220070ea074891795a8 467 PANTHER PTHR11119 18 442 1.8E-107 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS31355 df0d235ce15b6220070ea074891795a8 467 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 357 377 - T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 DC74_RS01465 56ae6abfa89880c3dbec9b847e78b7df 308 PANTHER PTHR21581:SF3 18 288 2.0E-53 T 23-04-2016 DC74_RS01465 56ae6abfa89880c3dbec9b847e78b7df 308 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 122 139 2.0E-10 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 DC74_RS01465 56ae6abfa89880c3dbec9b847e78b7df 308 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 68 79 2.0E-10 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 DC74_RS01465 56ae6abfa89880c3dbec9b847e78b7df 308 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 155 168 2.0E-10 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 DC74_RS01465 56ae6abfa89880c3dbec9b847e78b7df 308 SUPERFAMILY SSF56601 38 288 8.2E-54 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS01465 56ae6abfa89880c3dbec9b847e78b7df 308 PANTHER PTHR21581 18 288 2.0E-53 T 23-04-2016 DC74_RS01465 56ae6abfa89880c3dbec9b847e78b7df 308 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 36 273 2.3E-41 T 23-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 DC74_RS01465 56ae6abfa89880c3dbec9b847e78b7df 308 Gene3D G3DSA:3.40.710.10 37 288 2.2E-76 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS24030 7fc3ba81e9be38b68b15ce5269407df4 535 Pfam PF00171 Aldehyde dehydrogenase family 43 499 6.5E-143 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS24030 7fc3ba81e9be38b68b15ce5269407df4 535 PANTHER PTHR11699:SF202 8 535 0.0 T 23-04-2016 DC74_RS24030 7fc3ba81e9be38b68b15ce5269407df4 535 Gene3D G3DSA:3.40.605.10 41 285 2.8E-72 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS24030 7fc3ba81e9be38b68b15ce5269407df4 535 PANTHER PTHR11699 8 535 0.0 T 23-04-2016 DC74_RS24030 7fc3ba81e9be38b68b15ce5269407df4 535 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 271 278 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS24030 7fc3ba81e9be38b68b15ce5269407df4 535 Gene3D G3DSA:3.40.309.10 286 463 2.3E-66 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS24030 7fc3ba81e9be38b68b15ce5269407df4 535 SUPERFAMILY SSF53720 40 501 1.26E-142 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS17255 e4cbc5a2b56e24657d226551ccc6b3b5 306 Gene3D G3DSA:1.10.10.10 44 94 1.5E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17255 e4cbc5a2b56e24657d226551ccc6b3b5 306 SUPERFAMILY SSF53697 120 263 1.14E-6 T 23-04-2016 DC74_RS17255 e4cbc5a2b56e24657d226551ccc6b3b5 306 PANTHER PTHR30514 35 305 8.4E-76 T 23-04-2016 DC74_RS17255 e4cbc5a2b56e24657d226551ccc6b3b5 306 SUPERFAMILY SSF46689 44 104 1.0E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS17255 e4cbc5a2b56e24657d226551ccc6b3b5 306 Gene3D G3DSA:3.40.50.10490 95 264 4.3E-5 T 23-04-2016 DC74_RS17255 e4cbc5a2b56e24657d226551ccc6b3b5 306 Pfam PF01418 Helix-turn-helix domain, rpiR family 43 103 2.0E-11 T 23-04-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 DC74_RS17255 e4cbc5a2b56e24657d226551ccc6b3b5 306 PANTHER PTHR30514:SF3 35 305 8.4E-76 T 23-04-2016 DC74_RS11330 40ddad20ff8153d82a762daca6f2db3a 475 PANTHER PTHR30624:SF8 1 473 4.5E-148 T 23-04-2016 DC74_RS11330 40ddad20ff8153d82a762daca6f2db3a 475 PANTHER PTHR30624 1 473 4.5E-148 T 23-04-2016 DC74_RS11330 40ddad20ff8153d82a762daca6f2db3a 475 SUPERFAMILY SSF111283 10 468 4.84E-60 T 23-04-2016 DC74_RS11330 40ddad20ff8153d82a762daca6f2db3a 475 Pfam PF01523 Putative modulator of DNA gyrase 27 334 2.1E-31 T 23-04-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS31615 dceff64dce085a491d52a95f42ddeb5f 491 SUPERFAMILY SSF103473 283 481 3.4E-53 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS31615 dceff64dce085a491d52a95f42ddeb5f 491 SUPERFAMILY SSF103473 26 224 3.4E-53 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS31615 dceff64dce085a491d52a95f42ddeb5f 491 Pfam PF07690 Major Facilitator Superfamily 44 441 4.1E-42 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS31615 dceff64dce085a491d52a95f42ddeb5f 491 Gene3D G3DSA:1.20.1250.20 42 222 5.4E-28 T 23-04-2016 DC74_RS31615 dceff64dce085a491d52a95f42ddeb5f 491 Gene3D G3DSA:1.20.1250.20 298 476 3.4E-11 T 23-04-2016 DC74_RS31615 dceff64dce085a491d52a95f42ddeb5f 491 PANTHER PTHR23501 44 477 2.5E-69 T 23-04-2016 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 SUPERFAMILY SSF48264 12 406 1.83E-90 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PANTHER PTHR24286:SF42 39 406 1.2E-87 T 23-04-2016 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00359 B-class P450 signature 153 168 3.2E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00359 B-class P450 signature 136 152 3.2E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00359 B-class P450 signature 327 342 3.2E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00359 B-class P450 signature 86 97 3.2E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00359 B-class P450 signature 348 357 3.2E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00359 B-class P450 signature 357 368 3.2E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00359 B-class P450 signature 281 292 3.2E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00359 B-class P450 signature 299 326 3.2E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00359 B-class P450 signature 200 222 3.2E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 Gene3D G3DSA:1.10.630.10 12 406 4.1E-116 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 Pfam PF00067 Cytochrome P450 188 400 5.7E-32 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PANTHER PTHR24286 39 406 1.2E-87 T 23-04-2016 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00385 P450 superfamily signature 357 368 5.8E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00385 P450 superfamily signature 348 357 5.8E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00385 P450 superfamily signature 281 292 5.8E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06410 b5efbb39cb08291ff08cd13f4c2b03a1 411 PRINTS PR00385 P450 superfamily signature 246 263 5.8E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03850 57f583abe71ef8d874850c35d22aa185 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.54E-11 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS03850 57f583abe71ef8d874850c35d22aa185 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.54E-11 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS03850 57f583abe71ef8d874850c35d22aa185 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.54E-11 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS03850 57f583abe71ef8d874850c35d22aa185 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.7E-21 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS03850 57f583abe71ef8d874850c35d22aa185 300 Gene3D G3DSA:3.40.190.10 96 172 6.4E-10 T 23-04-2016 DC74_RS03850 57f583abe71ef8d874850c35d22aa185 300 SUPERFAMILY SSF46785 4 85 1.87E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03850 57f583abe71ef8d874850c35d22aa185 300 PANTHER PTHR30346 1 283 3.5E-61 T 23-04-2016 DC74_RS03850 57f583abe71ef8d874850c35d22aa185 300 Gene3D G3DSA:1.10.10.10 3 86 1.2E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03850 57f583abe71ef8d874850c35d22aa185 300 Gene3D G3DSA:3.40.190.10 173 257 2.2E-7 T 23-04-2016 DC74_RS03850 57f583abe71ef8d874850c35d22aa185 300 SUPERFAMILY SSF53850 99 287 7.24E-19 T 23-04-2016 DC74_RS03850 57f583abe71ef8d874850c35d22aa185 300 Pfam PF03466 LysR substrate binding domain 98 273 1.7E-18 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 SMART SM00421 161 218 3.5E-22 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 218 3.3E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 Pfam PF00072 Response regulator receiver domain 10 122 2.0E-27 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 Gene3D G3DSA:1.10.10.10 165 223 1.9E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 SUPERFAMILY SSF46894 155 223 7.14E-20 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 PANTHER PTHR26402 8 223 1.3E-75 T 23-04-2016 DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 Gene3D G3DSA:3.40.50.2300 6 164 1.6E-38 T 23-04-2016 DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 SUPERFAMILY SSF52172 7 137 4.84E-34 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 PANTHER PTHR26402:SF151 8 223 1.3E-75 T 23-04-2016 DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 2.2E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 2.2E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 2.2E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02420 460bf3dcb4028c5fe49502dc8e4df8c3 225 SMART SM00448 8 121 7.2E-31 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 SMART SM01260 56 443 3.8E-42 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 Pfam PF05147 Lanthionine synthetase C-like protein 57 443 1.0E-39 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01955 Frankia sp. LanC-like protein signature 255 275 1.2E-37 T 23-04-2016 IPR020434 LanC-like protein DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01955 Frankia sp. LanC-like protein signature 106 122 1.2E-37 T 23-04-2016 IPR020434 LanC-like protein DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01955 Frankia sp. LanC-like protein signature 354 374 1.2E-37 T 23-04-2016 IPR020434 LanC-like protein DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01955 Frankia sp. LanC-like protein signature 414 431 1.2E-37 T 23-04-2016 IPR020434 LanC-like protein DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01955 Frankia sp. LanC-like protein signature 306 329 1.2E-37 T 23-04-2016 IPR020434 LanC-like protein DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01955 Frankia sp. LanC-like protein signature 60 75 1.2E-37 T 23-04-2016 IPR020434 LanC-like protein DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01955 Frankia sp. LanC-like protein signature 231 255 1.2E-37 T 23-04-2016 IPR020434 LanC-like protein DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01955 Frankia sp. LanC-like protein signature 160 176 1.2E-37 T 23-04-2016 IPR020434 LanC-like protein DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01950 LanC-like protein superfamily signature 105 123 1.5E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01950 LanC-like protein superfamily signature 413 430 1.5E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01950 LanC-like protein superfamily signature 234 250 1.5E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01950 LanC-like protein superfamily signature 355 368 1.5E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01950 LanC-like protein superfamily signature 161 176 1.5E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 PRINTS PR01950 LanC-like protein superfamily signature 306 326 1.5E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS10025 67b442b38cf5c5a272514b61a108209a 445 SUPERFAMILY SSF158745 56 443 2.62E-61 T 23-04-2016 DC74_RS28990 794a6d68cffbc429b4b5d2e2f20e7ec3 664 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 5 177 1.6E-16 T 23-04-2016 IPR032856 Putative glycogen debranching enzyme, N-terminal DC74_RS28990 794a6d68cffbc429b4b5d2e2f20e7ec3 664 SUPERFAMILY SSF48208 221 649 1.64E-29 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 DC74_RS28990 794a6d68cffbc429b4b5d2e2f20e7ec3 664 PANTHER PTHR10569:SF1 393 614 1.1E-27 T 23-04-2016 DC74_RS28990 794a6d68cffbc429b4b5d2e2f20e7ec3 664 PANTHER PTHR10569 393 614 1.1E-27 T 23-04-2016 IPR010401 Glycogen debranching enzyme GO:0004134|GO:0004135|GO:0005980 KEGG: 00500+3.2.1.33+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 DC74_RS32455 649880f66f1ade89091def5278f4c163 123 Pfam PF05331 Protein of unknown function (DUF742) 14 123 1.9E-35 T 23-04-2016 IPR007995 Protein of unknown function DUF742 DC74_RS32455 649880f66f1ade89091def5278f4c163 123 PANTHER PTHR36221 13 123 3.5E-33 T 23-04-2016 DC74_RS32290 2f66687bd7e4f2820acb0589ecf5de0d 109 SUPERFAMILY SSF54909 1 107 5.36E-43 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS32290 2f66687bd7e4f2820acb0589ecf5de0d 109 ProDom PD012644 CYCLASE POLYKETIDE II SYNTHESIS ORF SYNTHASE JADI BIOSYNTHESIS ANTIBIOTIC CYCLASE-LIKE 2 107 2.0E-46 T 23-04-2016 IPR006765 Polyketide synthesis cyclase GO:0030639 DC74_RS32290 2f66687bd7e4f2820acb0589ecf5de0d 109 Gene3D G3DSA:3.30.70.1090 1 107 1.5E-46 T 23-04-2016 IPR006765 Polyketide synthesis cyclase GO:0030639 DC74_RS32290 2f66687bd7e4f2820acb0589ecf5de0d 109 Pfam PF04673 Polyketide synthesis cyclase 2 106 1.8E-42 T 23-04-2016 IPR006765 Polyketide synthesis cyclase GO:0030639 DC74_RS26395 2711e3b8831ce3cdbd9f9e24ff9a8d6f 650 SUPERFAMILY SSF53955 67 272 1.72E-61 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS26395 2711e3b8831ce3cdbd9f9e24ff9a8d6f 650 PANTHER PTHR32282 4 567 5.8E-158 T 23-04-2016 DC74_RS26395 2711e3b8831ce3cdbd9f9e24ff9a8d6f 650 SUPERFAMILY SSF56601 235 254 1.88E-42 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS26395 2711e3b8831ce3cdbd9f9e24ff9a8d6f 650 SUPERFAMILY SSF56601 284 535 1.88E-42 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS26395 2711e3b8831ce3cdbd9f9e24ff9a8d6f 650 Pfam PF00912 Transglycosylase 81 250 5.1E-54 T 23-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 DC74_RS26395 2711e3b8831ce3cdbd9f9e24ff9a8d6f 650 Pfam PF00905 Penicillin binding protein transpeptidase domain 355 533 1.3E-10 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS26395 2711e3b8831ce3cdbd9f9e24ff9a8d6f 650 Gene3D G3DSA:1.10.3810.10 76 251 1.4E-59 T 23-04-2016 DC74_RS26395 2711e3b8831ce3cdbd9f9e24ff9a8d6f 650 PANTHER PTHR32282:SF8 4 567 5.8E-158 T 23-04-2016 DC74_RS26395 2711e3b8831ce3cdbd9f9e24ff9a8d6f 650 Gene3D G3DSA:3.40.710.10 252 569 2.9E-50 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 Gene3D G3DSA:2.60.40.10 788 842 1.8E-13 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 Pfam PF07690 Major Facilitator Superfamily 40 436 3.9E-48 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 36 519 2.2E-71 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 Gene3D G3DSA:1.20.1250.20 40 209 1.2E-28 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 Gene3D G3DSA:1.20.1250.20 279 448 5.0E-23 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 Gene3D G3DSA:1.20.1250.20 498 523 5.0E-23 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 SUPERFAMILY SSF49478 788 856 1.49E-12 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 PANTHER PTHR23501:SF73 27 545 6.1E-191 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 PANTHER PTHR23501:SF73 568 586 6.1E-191 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 SUPERFAMILY SSF49478 703 776 1.02E-11 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 PRINTS PR01036 Tetracycline resistance protein TetB signature 160 184 6.8E-9 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 PRINTS PR01036 Tetracycline resistance protein TetB signature 39 63 6.8E-9 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 PRINTS PR01036 Tetracycline resistance protein TetB signature 130 150 6.8E-9 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 PRINTS PR01036 Tetracycline resistance protein TetB signature 427 446 6.8E-9 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 PANTHER PTHR23501 27 545 6.1E-191 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 PANTHER PTHR23501 568 586 6.1E-191 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 Gene3D G3DSA:2.60.40.1120 620 691 4.2E-8 T 23-04-2016 IPR014766 Carboxypeptidase, regulatory domain DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 SUPERFAMILY SSF49464 620 694 6.28E-9 T 23-04-2016 IPR008969 Carboxypeptidase-like, regulatory domain DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 Pfam PF13620 Carboxypeptidase regulatory-like domain 620 687 8.3E-9 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 Pfam PF13620 Carboxypeptidase regulatory-like domain 788 865 3.7E-12 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 Pfam PF13620 Carboxypeptidase regulatory-like domain 703 782 1.5E-11 T 23-04-2016 DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 Gene3D G3DSA:2.60.40.1120 702 782 1.8E-13 T 23-04-2016 IPR014766 Carboxypeptidase, regulatory domain DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 SUPERFAMILY SSF103473 274 446 3.53E-64 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 SUPERFAMILY SSF103473 497 522 3.53E-64 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21535 b54ce8660f6e91b1c9f953cf5a37097d 870 SUPERFAMILY SSF103473 28 220 3.53E-64 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS15235 7a81f01d516ba978f59946dde687da21 179 Gene3D G3DSA:3.40.630.30 43 174 7.2E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS15235 7a81f01d516ba978f59946dde687da21 179 PANTHER PTHR39173 15 171 4.4E-26 T 23-04-2016 DC74_RS15235 7a81f01d516ba978f59946dde687da21 179 Pfam PF13302 Acetyltransferase (GNAT) domain 43 162 3.0E-11 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS15235 7a81f01d516ba978f59946dde687da21 179 SUPERFAMILY SSF55729 45 171 6.13E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS30375 ae490ae4be7f7434643cdf0a375eb45c 229 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 5 219 5.8E-34 T 23-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS30375 ae490ae4be7f7434643cdf0a375eb45c 229 Pfam PF00290 Tryptophan synthase alpha chain 4 224 9.4E-42 T 23-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS30375 ae490ae4be7f7434643cdf0a375eb45c 229 SUPERFAMILY SSF51366 4 217 1.88E-42 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 DC74_RS30375 ae490ae4be7f7434643cdf0a375eb45c 229 Gene3D G3DSA:3.20.20.70 4 221 5.0E-49 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS14560 59931aaa1213370d5014415723cee68f 635 Gene3D G3DSA:1.10.443.10 294 477 1.5E-31 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS14560 59931aaa1213370d5014415723cee68f 635 Gene3D G3DSA:1.10.150.130 104 170 1.3E-6 T 23-04-2016 IPR023109 Integrase/recombinase, N-terminal DC74_RS14560 59931aaa1213370d5014415723cee68f 635 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 104 155 2.6E-7 T 23-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 DC74_RS14560 59931aaa1213370d5014415723cee68f 635 PANTHER PTHR30349:SF20 95 160 6.8E-25 T 23-04-2016 DC74_RS14560 59931aaa1213370d5014415723cee68f 635 PANTHER PTHR30349:SF20 219 499 6.8E-25 T 23-04-2016 DC74_RS14560 59931aaa1213370d5014415723cee68f 635 SUPERFAMILY SSF56349 218 478 5.89E-42 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DC74_RS14560 59931aaa1213370d5014415723cee68f 635 SUPERFAMILY SSF56349 104 159 5.89E-42 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DC74_RS14560 59931aaa1213370d5014415723cee68f 635 Pfam PF00589 Phage integrase family 316 470 1.5E-11 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS14560 59931aaa1213370d5014415723cee68f 635 PANTHER PTHR30349 95 160 6.8E-25 T 23-04-2016 DC74_RS14560 59931aaa1213370d5014415723cee68f 635 PANTHER PTHR30349 219 499 6.8E-25 T 23-04-2016 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 Gene3D G3DSA:3.90.1150.10 359 462 3.9E-28 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 Gene3D G3DSA:3.40.640.10 84 358 8.6E-97 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 PANTHER PTHR11999 1 462 1.0E-192 T 23-04-2016 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 SUPERFAMILY SSF53383 1 463 1.87E-127 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 47 66 9.9E-46 T 23-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 6 25 9.9E-46 T 23-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 29 46 9.9E-46 T 23-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 73 92 9.9E-46 T 23-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 387 406 9.9E-46 T 23-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 113 132 9.9E-46 T 23-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 94 112 9.9E-46 T 23-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 344 359 9.9E-46 T 23-04-2016 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 35 404 6.6E-99 T 23-04-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 Gene3D G3DSA:1.20.1340.10 1 81 1.2E-31 T 23-04-2016 DC74_RS00740 8fa201cd7e9d2f4afa8c3102116a4aa4 479 PANTHER PTHR11999:SF70 1 462 1.0E-192 T 23-04-2016 DC74_RS35260 1ba0bc50a83d2cb4d8a5787611df33af 529 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 53 143 1.4E-13 T 23-04-2016 IPR032093 Phospholipase D, N-terminal DC74_RS35260 1ba0bc50a83d2cb4d8a5787611df33af 529 Gene3D G3DSA:3.60.21.10 149 526 7.9E-37 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS35260 1ba0bc50a83d2cb4d8a5787611df33af 529 SUPERFAMILY SSF56300 150 523 7.59E-40 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS35260 1ba0bc50a83d2cb4d8a5787611df33af 529 PANTHER PTHR22953:SF40 232 416 3.3E-144 T 23-04-2016 DC74_RS35260 1ba0bc50a83d2cb4d8a5787611df33af 529 PANTHER PTHR22953:SF40 10 203 3.3E-144 T 23-04-2016 DC74_RS35260 1ba0bc50a83d2cb4d8a5787611df33af 529 PANTHER PTHR22953 232 416 3.3E-144 T 23-04-2016 DC74_RS35260 1ba0bc50a83d2cb4d8a5787611df33af 529 PANTHER PTHR22953 10 203 3.3E-144 T 23-04-2016 DC74_RS35260 1ba0bc50a83d2cb4d8a5787611df33af 529 Pfam PF09423 PhoD-like phosphatase 161 508 1.4E-77 T 23-04-2016 IPR018946 Alkaline phosphatase D-related DC74_RS17690 f2c143d156d74f5c5de8469559b16fc4 406 SUPERFAMILY SSF48264 23 397 2.23E-77 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS17690 f2c143d156d74f5c5de8469559b16fc4 406 PANTHER PTHR11712 23 383 4.7E-77 T 23-04-2016 DC74_RS17690 f2c143d156d74f5c5de8469559b16fc4 406 Gene3D G3DSA:1.10.630.10 17 401 7.2E-99 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS17690 f2c143d156d74f5c5de8469559b16fc4 406 PRINTS PR00359 B-class P450 signature 198 220 5.5E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17690 f2c143d156d74f5c5de8469559b16fc4 406 PRINTS PR00359 B-class P450 signature 142 158 5.5E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17690 f2c143d156d74f5c5de8469559b16fc4 406 PRINTS PR00359 B-class P450 signature 354 365 5.5E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17690 f2c143d156d74f5c5de8469559b16fc4 406 PRINTS PR00359 B-class P450 signature 95 106 5.5E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17690 f2c143d156d74f5c5de8469559b16fc4 406 PRINTS PR00359 B-class P450 signature 278 289 5.5E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17690 f2c143d156d74f5c5de8469559b16fc4 406 PRINTS PR00359 B-class P450 signature 345 354 5.5E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17690 f2c143d156d74f5c5de8469559b16fc4 406 PRINTS PR00359 B-class P450 signature 295 322 5.5E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17690 f2c143d156d74f5c5de8469559b16fc4 406 PRINTS PR00359 B-class P450 signature 159 174 5.5E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS17690 f2c143d156d74f5c5de8469559b16fc4 406 Pfam PF00067 Cytochrome P450 276 375 5.6E-15 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS09870 3c86f82f9f0e8bd60c30bd35af25d7e9 183 PANTHER PTHR30055 1 178 2.4E-19 T 23-04-2016 DC74_RS09870 3c86f82f9f0e8bd60c30bd35af25d7e9 183 SUPERFAMILY SSF46689 4 64 7.48E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS09870 3c86f82f9f0e8bd60c30bd35af25d7e9 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 52 3.1E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS09870 3c86f82f9f0e8bd60c30bd35af25d7e9 183 SUPERFAMILY SSF48498 106 178 1.59E-7 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS09870 3c86f82f9f0e8bd60c30bd35af25d7e9 183 Gene3D G3DSA:1.10.357.10 4 177 3.4E-25 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS20230 7174ba6f2d4fed75ae2bfdc9aab136d5 265 Gene3D G3DSA:3.20.20.370 64 253 1.4E-64 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS20230 7174ba6f2d4fed75ae2bfdc9aab136d5 265 SUPERFAMILY SSF88713 64 253 1.85E-59 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS20230 7174ba6f2d4fed75ae2bfdc9aab136d5 265 Pfam PF01522 Polysaccharide deacetylase 67 186 1.7E-38 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS20230 7174ba6f2d4fed75ae2bfdc9aab136d5 265 PANTHER PTHR10587 55 253 1.2E-59 T 23-04-2016 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 Gene3D G3DSA:1.10.540.10 4 115 5.2E-24 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 369 388 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 266 410 1.6E-52 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 1.5E-25 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 SUPERFAMILY SSF47203 266 414 6.12E-54 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 115 1.9E-14 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 Gene3D G3DSA:2.40.110.10 125 222 8.9E-37 T 23-04-2016 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 PANTHER PTHR10909 249 416 9.5E-123 T 23-04-2016 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 PANTHER PTHR10909 1 232 9.5E-123 T 23-04-2016 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 PANTHER PTHR10909:SF121 249 416 9.5E-123 T 23-04-2016 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 PANTHER PTHR10909:SF121 1 232 9.5E-123 T 23-04-2016 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 SUPERFAMILY SSF56645 5 235 1.16E-58 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS35700 ac466e16c0774d061ca89130ff2516ba 416 Gene3D G3DSA:1.20.140.10 223 414 1.8E-66 T 23-04-2016 DC74_RS23945 0bd246193247c429456ffa60f846d80f 279 SMART SM00382 52 248 2.5E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS23945 0bd246193247c429456ffa60f846d80f 279 PANTHER PTHR24220:SF593 29 246 1.0E-161 T 23-04-2016 DC74_RS23945 0bd246193247c429456ffa60f846d80f 279 Gene3D G3DSA:3.40.50.300 23 246 1.3E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23945 0bd246193247c429456ffa60f846d80f 279 PANTHER PTHR24220 29 246 1.0E-161 T 23-04-2016 DC74_RS23945 0bd246193247c429456ffa60f846d80f 279 SUPERFAMILY SSF52540 26 247 1.49E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23945 0bd246193247c429456ffa60f846d80f 279 Pfam PF00005 ABC transporter 44 186 4.9E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS31735 780bf2d483b94757bd60bb18ddd32771 165 SUPERFAMILY SSF55811 16 149 5.01E-23 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS31735 780bf2d483b94757bd60bb18ddd32771 165 Gene3D G3DSA:3.90.79.10 17 148 1.5E-22 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS31735 780bf2d483b94757bd60bb18ddd32771 165 PANTHER PTHR22769:SF24 17 152 3.0E-12 T 23-04-2016 DC74_RS31735 780bf2d483b94757bd60bb18ddd32771 165 Pfam PF00293 NUDIX domain 21 133 8.2E-15 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS31735 780bf2d483b94757bd60bb18ddd32771 165 PANTHER PTHR22769 17 152 3.0E-12 T 23-04-2016 DC74_RS05020 cd092e52905587e95e8583976e3816a2 427 SUPERFAMILY SSF51621 5 426 3.14E-158 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS05020 cd092e52905587e95e8583976e3816a2 427 PIRSF PIRSF001362 1 427 1.7E-238 T 23-04-2016 DC74_RS05020 cd092e52905587e95e8583976e3816a2 427 Pfam PF00463 Isocitrate lyase family 14 250 1.4E-54 T 23-04-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969|UniPathway: UPA00703 DC74_RS05020 cd092e52905587e95e8583976e3816a2 427 Pfam PF00463 Isocitrate lyase family 252 426 1.0E-50 T 23-04-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969|UniPathway: UPA00703 DC74_RS05020 cd092e52905587e95e8583976e3816a2 427 Gene3D G3DSA:3.20.20.60 9 408 7.8E-164 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS05020 cd092e52905587e95e8583976e3816a2 427 PANTHER PTHR21631 5 427 3.3E-166 T 23-04-2016 DC74_RS05020 cd092e52905587e95e8583976e3816a2 427 ProSitePatterns PS00161 Isocitrate lyase signature. 188 193 - T 23-04-2016 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 DC74_RS05020 cd092e52905587e95e8583976e3816a2 427 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 9 250 1.9E-104 T 23-04-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969|UniPathway: UPA00703 DC74_RS05020 cd092e52905587e95e8583976e3816a2 427 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 251 426 5.1E-84 T 23-04-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969|UniPathway: UPA00703 DC74_RS01680 6f63886e39421722588edf6fc2ffb883 256 PIRSF PIRSF015957 1 245 2.2E-115 T 23-04-2016 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|KEGG: 00902+4.2.3.15|MetaCyc: PWY-3041|MetaCyc: PWY-5423|MetaCyc: PWY-7410 DC74_RS01680 6f63886e39421722588edf6fc2ffb883 256 Pfam PF04476 Putative methanogenic enzyme for methanofuran 3 232 3.1E-81 T 23-04-2016 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|KEGG: 00902+4.2.3.15|MetaCyc: PWY-3041|MetaCyc: PWY-5423|MetaCyc: PWY-7410 DC74_RS01680 6f63886e39421722588edf6fc2ffb883 256 SUPERFAMILY SSF51366 11 219 1.55E-6 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 DC74_RS29170 ee583217e3269dd5282ccaad803d23e0 173 Pfam PF00692 dUTPase 20 149 4.1E-30 T 23-04-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 DC74_RS29170 ee583217e3269dd5282ccaad803d23e0 173 TIGRFAM TIGR00576 dut: dUTP diphosphatase 12 149 3.0E-48 T 23-04-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|UniPathway: UPA00610 DC74_RS29170 ee583217e3269dd5282ccaad803d23e0 173 PANTHER PTHR11241:SF0 5 159 1.8E-48 T 23-04-2016 DC74_RS29170 ee583217e3269dd5282ccaad803d23e0 173 SUPERFAMILY SSF51283 8 149 1.57E-42 T 23-04-2016 IPR029054 dUTPase-like DC74_RS29170 ee583217e3269dd5282ccaad803d23e0 173 Gene3D G3DSA:2.70.40.10 7 149 6.5E-51 T 23-04-2016 IPR029054 dUTPase-like DC74_RS29170 ee583217e3269dd5282ccaad803d23e0 173 PANTHER PTHR11241 5 159 1.8E-48 T 23-04-2016 DC74_RS29170 ee583217e3269dd5282ccaad803d23e0 173 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 8 150 30.27 T 23-04-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|UniPathway: UPA00610 DC74_RS11730 39ddda05b63e9943574d9dc76cbc484c 395 SUPERFAMILY SSF101960 38 391 1.14E-92 T 23-04-2016 DC74_RS11730 39ddda05b63e9943574d9dc76cbc484c 395 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 113 382 1.3E-74 T 23-04-2016 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 DC74_RS11730 39ddda05b63e9943574d9dc76cbc484c 395 PANTHER PTHR30508 28 393 9.6E-95 T 23-04-2016 DC74_RS11730 39ddda05b63e9943574d9dc76cbc484c 395 PANTHER PTHR30508:SF0 28 393 9.6E-95 T 23-04-2016 DC74_RS11730 39ddda05b63e9943574d9dc76cbc484c 395 Pfam PF01458 Uncharacterized protein family (UPF0051) 144 365 3.4E-70 T 23-04-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 DC74_RS18315 ba90b3c828e007a6489e9649cb296032 396 SUPERFAMILY SSF53901 241 361 1.25E-21 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS18315 ba90b3c828e007a6489e9649cb296032 396 Gene3D G3DSA:3.40.47.10 152 189 6.2E-16 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS18315 ba90b3c828e007a6489e9649cb296032 396 Gene3D G3DSA:3.40.47.10 249 360 6.2E-16 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS18315 ba90b3c828e007a6489e9649cb296032 396 PANTHER PTHR18919 9 360 2.1E-100 T 23-04-2016 DC74_RS18315 ba90b3c828e007a6489e9649cb296032 396 Pfam PF02803 Thiolase, C-terminal domain 256 358 4.2E-7 T 23-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 DC74_RS18315 ba90b3c828e007a6489e9649cb296032 396 SUPERFAMILY SSF53901 15 232 9.02E-19 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS18315 ba90b3c828e007a6489e9649cb296032 396 Gene3D G3DSA:3.40.47.10 199 231 3.5E-12 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS18315 ba90b3c828e007a6489e9649cb296032 396 Gene3D G3DSA:3.40.47.10 29 116 3.5E-12 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS18315 ba90b3c828e007a6489e9649cb296032 396 PIRSF PIRSF000429 9 383 6.6E-30 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS18315 ba90b3c828e007a6489e9649cb296032 396 PANTHER PTHR18919:SF108 9 360 2.1E-100 T 23-04-2016 DC74_RS26220 e75cce88235d4e488c94a7bf96a7bb84 488 PANTHER PTHR10566 1 440 2.0E-259 T 23-04-2016 DC74_RS26220 e75cce88235d4e488c94a7bf96a7bb84 488 SUPERFAMILY SSF56112 195 313 5.57E-23 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS26220 e75cce88235d4e488c94a7bf96a7bb84 488 SUPERFAMILY SSF56112 95 158 5.57E-23 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS26220 e75cce88235d4e488c94a7bf96a7bb84 488 PANTHER PTHR10566:SF64 1 440 2.0E-259 T 23-04-2016 DC74_RS26220 e75cce88235d4e488c94a7bf96a7bb84 488 Pfam PF03109 ABC1 family 113 227 2.1E-30 T 23-04-2016 IPR004147 UbiB domain DC74_RS14630 da0ac0d4f73bcbbe02804ca8e4e30737 336 Gene3D G3DSA:3.20.20.140 13 335 2.2E-102 T 23-04-2016 DC74_RS14630 da0ac0d4f73bcbbe02804ca8e4e30737 336 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 14 332 2.5E-117 T 23-04-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 DC74_RS14630 da0ac0d4f73bcbbe02804ca8e4e30737 336 SUPERFAMILY SSF51556 12 331 7.83E-85 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS14630 da0ac0d4f73bcbbe02804ca8e4e30737 336 PANTHER PTHR11409:SF41 12 335 2.1E-165 T 23-04-2016 DC74_RS14630 da0ac0d4f73bcbbe02804ca8e4e30737 336 Hamap MF_01962 Adenine deaminase. 10 322 83.397 T 23-04-2016 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 DC74_RS14630 da0ac0d4f73bcbbe02804ca8e4e30737 336 Pfam PF00962 Adenosine/AMP deaminase 14 330 4.2E-75 T 23-04-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 DC74_RS14630 da0ac0d4f73bcbbe02804ca8e4e30737 336 PANTHER PTHR11409 12 335 2.1E-165 T 23-04-2016 DC74_RS02165 8e24d78491e73199dd2e072098425456 344 Pfam PF00962 Adenosine/AMP deaminase 18 334 1.2E-64 T 23-04-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 DC74_RS02165 8e24d78491e73199dd2e072098425456 344 PANTHER PTHR11409:SF36 5 343 7.5E-91 T 23-04-2016 DC74_RS02165 8e24d78491e73199dd2e072098425456 344 PANTHER PTHR11409 5 343 7.5E-91 T 23-04-2016 DC74_RS02165 8e24d78491e73199dd2e072098425456 344 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 18 334 1.9E-83 T 23-04-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 DC74_RS02165 8e24d78491e73199dd2e072098425456 344 Gene3D G3DSA:3.20.20.140 13 341 4.7E-89 T 23-04-2016 DC74_RS02165 8e24d78491e73199dd2e072098425456 344 SUPERFAMILY SSF51556 13 334 7.61E-68 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS35095 e75298e8308ff51cd160733398793855 337 Gene3D G3DSA:3.40.50.1820 71 329 2.0E-32 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35095 e75298e8308ff51cd160733398793855 337 Gene3D G3DSA:3.40.50.1820 17 35 2.0E-32 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35095 e75298e8308ff51cd160733398793855 337 Pfam PF00756 Putative esterase 95 279 3.7E-12 T 23-04-2016 IPR000801 Putative esterase DC74_RS35095 e75298e8308ff51cd160733398793855 337 SUPERFAMILY SSF53474 70 326 6.83E-24 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS14445 b993e248939d2b9b6e5c34007ff8670d 281 SMART SM00530 25 82 1.3E-10 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS14445 b993e248939d2b9b6e5c34007ff8670d 281 PANTHER PTHR10245 30 279 1.8E-40 T 23-04-2016 DC74_RS14445 b993e248939d2b9b6e5c34007ff8670d 281 Gene3D G3DSA:1.10.260.40 30 78 3.1E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS14445 b993e248939d2b9b6e5c34007ff8670d 281 Pfam PF13560 Helix-turn-helix domain 30 79 1.4E-12 T 23-04-2016 DC74_RS14445 b993e248939d2b9b6e5c34007ff8670d 281 PANTHER PTHR10245:SF7 30 279 1.8E-40 T 23-04-2016 DC74_RS14445 b993e248939d2b9b6e5c34007ff8670d 281 SUPERFAMILY SSF47413 30 78 2.0E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS39355 0ce8e8397450e4ac28bcf51418ad0ab0 179 Pfam PF00156 Phosphoribosyl transferase domain 35 155 1.7E-15 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 DC74_RS39355 0ce8e8397450e4ac28bcf51418ad0ab0 179 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 11 177 30.239 T 23-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 DC74_RS39355 0ce8e8397450e4ac28bcf51418ad0ab0 179 PANTHER PTHR32315 1 175 9.5E-60 T 23-04-2016 DC74_RS39355 0ce8e8397450e4ac28bcf51418ad0ab0 179 SUPERFAMILY SSF53271 9 169 3.02E-41 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS39355 0ce8e8397450e4ac28bcf51418ad0ab0 179 Gene3D G3DSA:3.40.50.2020 8 175 2.7E-54 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS23995 0bb1444e405b187a18bcee9d11845a56 405 SUPERFAMILY SSF55874 290 402 8.53E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23995 0bb1444e405b187a18bcee9d11845a56 405 PANTHER PTHR24421:SF26 36 401 7.6E-70 T 23-04-2016 DC74_RS23995 0bb1444e405b187a18bcee9d11845a56 405 PANTHER PTHR24421 36 401 7.6E-70 T 23-04-2016 DC74_RS23995 0bb1444e405b187a18bcee9d11845a56 405 Pfam PF07730 Histidine kinase 179 242 7.9E-15 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS03670 ca10689fe3cbdd4c2af517f5380a7560 214 SUPERFAMILY SSF46689 22 100 6.16E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03670 ca10689fe3cbdd4c2af517f5380a7560 214 PANTHER PTHR30055 12 202 1.4E-19 T 23-04-2016 DC74_RS03670 ca10689fe3cbdd4c2af517f5380a7560 214 PANTHER PTHR30055:SF2 12 202 1.4E-19 T 23-04-2016 DC74_RS03670 ca10689fe3cbdd4c2af517f5380a7560 214 SUPERFAMILY SSF48498 99 206 6.52E-7 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS03670 ca10689fe3cbdd4c2af517f5380a7560 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 76 1.4E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03670 ca10689fe3cbdd4c2af517f5380a7560 214 Gene3D G3DSA:1.10.357.10 24 210 8.4E-31 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 23-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 PANTHER PTHR30154 1 143 8.2E-50 T 23-04-2016 DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 SUPERFAMILY SSF46785 1 60 1.22E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 9.5E-17 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 SUPERFAMILY SSF54909 61 143 1.47E-18 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 Gene3D G3DSA:3.30.70.920 54 144 5.1E-24 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 Gene3D G3DSA:1.10.10.10 1 52 3.0E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 8.2E-14 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 8.2E-14 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 8.2E-14 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 5.9E-19 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 PANTHER PTHR30154:SF2 1 143 8.2E-50 T 23-04-2016 DC74_RS19225 62a5c2ad294a6b6108706d84ce991dcf 152 SMART SM00344 1 108 2.2E-39 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS33510 bdfbb19e0650ef3249f55374148b9a60 358 Pfam PF00149 Calcineurin-like phosphoesterase 42 267 4.1E-11 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS33510 bdfbb19e0650ef3249f55374148b9a60 358 PANTHER PTHR10161 139 330 7.7E-27 T 23-04-2016 DC74_RS33510 bdfbb19e0650ef3249f55374148b9a60 358 PANTHER PTHR10161 35 121 7.7E-27 T 23-04-2016 DC74_RS33510 bdfbb19e0650ef3249f55374148b9a60 358 SUPERFAMILY SSF56300 40 329 3.8E-46 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS33510 bdfbb19e0650ef3249f55374148b9a60 358 Gene3D G3DSA:3.60.21.10 36 330 3.1E-57 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS25145 317c40ec3c3b7ed554f4de7b1dd7eab1 264 PANTHER PTHR11941:SF93 8 261 5.2E-114 T 23-04-2016 DC74_RS25145 317c40ec3c3b7ed554f4de7b1dd7eab1 264 PANTHER PTHR11941 8 261 5.2E-114 T 23-04-2016 DC74_RS25145 317c40ec3c3b7ed554f4de7b1dd7eab1 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 105 125 - T 23-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 DC74_RS25145 317c40ec3c3b7ed554f4de7b1dd7eab1 264 Gene3D G3DSA:3.90.226.10 10 206 3.4E-66 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS25145 317c40ec3c3b7ed554f4de7b1dd7eab1 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 262 1.3E-61 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS25145 317c40ec3c3b7ed554f4de7b1dd7eab1 264 Gene3D G3DSA:1.10.12.10 207 264 5.3E-17 T 23-04-2016 IPR014748 Crontonase, C-terminal DC74_RS25145 317c40ec3c3b7ed554f4de7b1dd7eab1 264 SUPERFAMILY SSF52096 8 263 1.99E-80 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS19950 e6df0ed6c7418ec0592662f4cda2d156 231 Pfam PF01025 GrpE 41 187 4.6E-35 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS19950 e6df0ed6c7418ec0592662f4cda2d156 231 PRINTS PR00773 GrpE protein signature 166 185 5.1E-25 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS19950 e6df0ed6c7418ec0592662f4cda2d156 231 PRINTS PR00773 GrpE protein signature 92 107 5.1E-25 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS19950 e6df0ed6c7418ec0592662f4cda2d156 231 PRINTS PR00773 GrpE protein signature 139 154 5.1E-25 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS19950 e6df0ed6c7418ec0592662f4cda2d156 231 PRINTS PR00773 GrpE protein signature 64 80 5.1E-25 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS19950 e6df0ed6c7418ec0592662f4cda2d156 231 PANTHER PTHR21237 17 191 8.3E-42 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS19950 e6df0ed6c7418ec0592662f4cda2d156 231 Gene3D G3DSA:3.90.20.20 44 130 3.8E-19 T 23-04-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil DC74_RS19950 e6df0ed6c7418ec0592662f4cda2d156 231 Gene3D G3DSA:2.30.22.10 131 188 4.1E-22 T 23-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 DC74_RS19950 e6df0ed6c7418ec0592662f4cda2d156 231 SUPERFAMILY SSF58014 45 131 1.01E-17 T 23-04-2016 DC74_RS19950 e6df0ed6c7418ec0592662f4cda2d156 231 Hamap MF_01151 Protein GrpE [grpE]. 3 187 17.489 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS19950 e6df0ed6c7418ec0592662f4cda2d156 231 SUPERFAMILY SSF51064 133 188 4.84E-16 T 23-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 DC74_RS19950 e6df0ed6c7418ec0592662f4cda2d156 231 ProSitePatterns PS01071 grpE protein signature. 142 185 - T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 DC74_RS07505 4492b84a4f4e26b4b204e2ddc1e47c7f 375 SUPERFAMILY SSF54909 19 107 2.08E-18 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS07505 4492b84a4f4e26b4b204e2ddc1e47c7f 375 Gene3D G3DSA:3.30.70.900 22 108 7.8E-15 T 23-04-2016 DC74_RS07505 4492b84a4f4e26b4b204e2ddc1e47c7f 375 Pfam PF03992 Antibiotic biosynthesis monooxygenase 19 90 1.7E-15 T 23-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain DC74_RS07505 4492b84a4f4e26b4b204e2ddc1e47c7f 375 Pfam PF04486 SchA/CurD like domain 137 248 1.5E-45 T 23-04-2016 IPR007575 SchA/CurD-like domain DC74_RS16680 2eae14e88769ec40cfde76a8fd460904 303 Pfam PF02687 FtsX-like permease family 184 302 9.1E-13 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS16680 2eae14e88769ec40cfde76a8fd460904 303 PIRSF PIRSF003097 1 303 6.1E-74 T 23-04-2016 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 DC74_RS16680 2eae14e88769ec40cfde76a8fd460904 303 PANTHER PTHR30489 127 303 2.5E-31 T 23-04-2016 DC74_RS29365 13e62839b7d7376fb6d9b591961995e5 341 Pfam PF03756 A-factor biosynthesis hotdog domain 38 173 3.2E-26 T 23-04-2016 IPR005509 A-factor biosynthesis hotdog domain DC74_RS29365 13e62839b7d7376fb6d9b591961995e5 341 Pfam PF03756 A-factor biosynthesis hotdog domain 208 330 1.3E-20 T 23-04-2016 IPR005509 A-factor biosynthesis hotdog domain DC74_RS31690 ea81280cc25de97478da03a04e576844 619 PANTHER PTHR11686:SF12 403 619 2.9E-300 T 23-04-2016 DC74_RS31690 ea81280cc25de97478da03a04e576844 619 PANTHER PTHR11686 403 619 2.9E-300 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31690 ea81280cc25de97478da03a04e576844 619 PANTHER PTHR11686 2 355 2.9E-300 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31690 ea81280cc25de97478da03a04e576844 619 SUPERFAMILY SSF56235 420 618 5.69E-122 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS31690 ea81280cc25de97478da03a04e576844 619 SUPERFAMILY SSF56235 2 347 5.69E-122 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS31690 ea81280cc25de97478da03a04e576844 619 PANTHER PTHR11686:SF12 2 355 2.9E-300 T 23-04-2016 DC74_RS31690 ea81280cc25de97478da03a04e576844 619 Pfam PF01019 Gamma-glutamyltranspeptidase 28 611 3.0E-109 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31690 ea81280cc25de97478da03a04e576844 619 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 2.8E-17 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31690 ea81280cc25de97478da03a04e576844 619 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 105 123 2.8E-17 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31690 ea81280cc25de97478da03a04e576844 619 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 477 492 2.8E-17 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31690 ea81280cc25de97478da03a04e576844 619 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 123 142 2.8E-17 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS29955 d273dd8d0bfbd2319acd70993c340ec0 210 PANTHER PTHR22935:SF73 1 196 2.3E-23 T 23-04-2016 DC74_RS29955 d273dd8d0bfbd2319acd70993c340ec0 210 Pfam PF01427 D-ala-D-ala dipeptidase 62 197 3.2E-17 T 23-04-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 DC74_RS29955 d273dd8d0bfbd2319acd70993c340ec0 210 SUPERFAMILY SSF55166 43 203 6.28E-34 T 23-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain DC74_RS29955 d273dd8d0bfbd2319acd70993c340ec0 210 Gene3D G3DSA:3.30.1380.10 44 203 8.6E-34 T 23-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain DC74_RS29955 d273dd8d0bfbd2319acd70993c340ec0 210 PANTHER PTHR22935 1 196 2.3E-23 T 23-04-2016 DC74_RS23780 c24da76188a1923ba3f5646433e28c8e 145 Pfam PF12802 MarR family 36 93 1.1E-13 T 23-04-2016 DC74_RS23780 c24da76188a1923ba3f5646433e28c8e 145 PANTHER PTHR39515:SF2 1 144 9.4E-65 T 23-04-2016 DC74_RS23780 c24da76188a1923ba3f5646433e28c8e 145 Gene3D G3DSA:1.10.10.10 9 135 5.7E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23780 c24da76188a1923ba3f5646433e28c8e 145 PANTHER PTHR39515 1 144 9.4E-65 T 23-04-2016 DC74_RS23780 c24da76188a1923ba3f5646433e28c8e 145 SUPERFAMILY SSF46785 12 136 1.04E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23780 c24da76188a1923ba3f5646433e28c8e 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 7.5E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS23780 c24da76188a1923ba3f5646433e28c8e 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 7.5E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS23780 c24da76188a1923ba3f5646433e28c8e 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 7.5E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS23780 c24da76188a1923ba3f5646433e28c8e 145 SMART SM00347 29 129 6.4E-21 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS23780 c24da76188a1923ba3f5646433e28c8e 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS32330 c8ee5048e367a9c52b7259f3d9e11990 429 Pfam PF07690 Major Facilitator Superfamily 275 426 6.9E-10 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS32330 c8ee5048e367a9c52b7259f3d9e11990 429 Pfam PF07690 Major Facilitator Superfamily 34 268 4.4E-31 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS32330 c8ee5048e367a9c52b7259f3d9e11990 429 Gene3D G3DSA:1.20.1250.20 220 421 2.5E-15 T 23-04-2016 DC74_RS32330 c8ee5048e367a9c52b7259f3d9e11990 429 Gene3D G3DSA:1.20.1250.20 24 208 1.4E-22 T 23-04-2016 DC74_RS32330 c8ee5048e367a9c52b7259f3d9e11990 429 PANTHER PTHR23501 14 419 1.7E-63 T 23-04-2016 DC74_RS32330 c8ee5048e367a9c52b7259f3d9e11990 429 SUPERFAMILY SSF103473 1 420 3.14E-57 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS19325 d648e4fd10dcdad94c791e788b18b0d2 394 Gene3D G3DSA:3.90.1150.10 2 34 2.9E-29 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS19325 d648e4fd10dcdad94c791e788b18b0d2 394 Gene3D G3DSA:3.90.1150.10 283 385 2.9E-29 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS19325 d648e4fd10dcdad94c791e788b18b0d2 394 Pfam PF00202 Aminotransferase class-III 3 382 2.4E-79 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS19325 d648e4fd10dcdad94c791e788b18b0d2 394 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 199 235 - T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS19325 d648e4fd10dcdad94c791e788b18b0d2 394 PANTHER PTHR11986 1 394 1.6E-181 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS19325 d648e4fd10dcdad94c791e788b18b0d2 394 PANTHER PTHR11986:SF5 1 394 1.6E-181 T 23-04-2016 DC74_RS19325 d648e4fd10dcdad94c791e788b18b0d2 394 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 1 389 86.725 T 23-04-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188|UniPathway: UPA00251 DC74_RS19325 d648e4fd10dcdad94c791e788b18b0d2 394 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 3 382 5.2E-161 T 23-04-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188|UniPathway: UPA00251 DC74_RS19325 d648e4fd10dcdad94c791e788b18b0d2 394 SUPERFAMILY SSF53383 2 385 3.66E-106 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS19325 d648e4fd10dcdad94c791e788b18b0d2 394 Gene3D G3DSA:3.40.640.10 35 281 7.6E-76 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS23390 e8c8000b8c02237bf8c9d40e669f9a43 147 PANTHER PTHR33204 11 146 6.5E-41 T 23-04-2016 DC74_RS23390 e8c8000b8c02237bf8c9d40e669f9a43 147 SUPERFAMILY SSF46785 19 145 7.93E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23390 e8c8000b8c02237bf8c9d40e669f9a43 147 PANTHER PTHR33204:SF7 11 146 6.5E-41 T 23-04-2016 DC74_RS23390 e8c8000b8c02237bf8c9d40e669f9a43 147 Pfam PF01638 HxlR-like helix-turn-helix 63 133 2.0E-20 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS23390 e8c8000b8c02237bf8c9d40e669f9a43 147 Gene3D G3DSA:1.10.10.10 9 145 1.1E-48 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS30225 e4b7ef3bff789dc718814bc97ce17ea8 159 Gene3D G3DSA:3.40.630.30 3 146 4.0E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS30225 e4b7ef3bff789dc718814bc97ce17ea8 159 Pfam PF00583 Acetyltransferase (GNAT) family 63 145 6.1E-10 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS30225 e4b7ef3bff789dc718814bc97ce17ea8 159 PANTHER PTHR23091 3 145 4.7E-17 T 23-04-2016 DC74_RS30225 e4b7ef3bff789dc718814bc97ce17ea8 159 SUPERFAMILY SSF55729 3 145 2.49E-24 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS22950 e63942fc4df51b6fb24adbb746177825 359 PANTHER PTHR30425 80 359 6.0E-107 T 23-04-2016 DC74_RS22950 e63942fc4df51b6fb24adbb746177825 359 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 85 351 3.5E-85 T 23-04-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 DC74_RS22950 e63942fc4df51b6fb24adbb746177825 359 Gene3D G3DSA:1.10.3720.10 83 353 7.4E-45 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS22950 e63942fc4df51b6fb24adbb746177825 359 PANTHER PTHR30425:SF0 80 359 6.0E-107 T 23-04-2016 DC74_RS22950 e63942fc4df51b6fb24adbb746177825 359 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 158 357 4.3E-25 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS22950 e63942fc4df51b6fb24adbb746177825 359 SUPERFAMILY SSF161098 92 346 8.18E-41 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS10560 316f6146a77e895cdbecb6dea1dc85f9 203 Gene3D G3DSA:1.10.10.10 5 62 3.8E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10560 316f6146a77e895cdbecb6dea1dc85f9 203 SMART SM00418 4 99 0.0017 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS10560 316f6146a77e895cdbecb6dea1dc85f9 203 Pfam PF12840 Helix-turn-helix domain 9 60 3.1E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10560 316f6146a77e895cdbecb6dea1dc85f9 203 SUPERFAMILY SSF46785 4 117 9.93E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29720 5c0828e8ef96a949a95d355471118127 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 304 3.9E-15 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS29720 5c0828e8ef96a949a95d355471118127 307 PANTHER PTHR30193:SF15 7 306 4.3E-71 T 23-04-2016 DC74_RS29720 5c0828e8ef96a949a95d355471118127 307 Gene3D G3DSA:1.10.3720.10 57 303 6.6E-59 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS29720 5c0828e8ef96a949a95d355471118127 307 SUPERFAMILY SSF161098 51 294 2.75E-49 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS29720 5c0828e8ef96a949a95d355471118127 307 PANTHER PTHR30193 7 306 4.3E-71 T 23-04-2016 DC74_RS12520 3b8af8b505a8e4ba7295e966d1488b81 244 SUPERFAMILY SSF51419 4 238 1.21E-60 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS12520 3b8af8b505a8e4ba7295e966d1488b81 244 Pfam PF01168 Alanine racemase, N-terminal domain 13 241 3.3E-23 T 23-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS12520 3b8af8b505a8e4ba7295e966d1488b81 244 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 81 95 - T 23-04-2016 IPR011078 Uncharacterised protein family UPF0001 DC74_RS12520 3b8af8b505a8e4ba7295e966d1488b81 244 PANTHER PTHR10146 5 240 4.9E-68 T 23-04-2016 IPR011078 Uncharacterised protein family UPF0001 DC74_RS12520 3b8af8b505a8e4ba7295e966d1488b81 244 PIRSF PIRSF004848 3 244 1.6E-63 T 23-04-2016 IPR011078 Uncharacterised protein family UPF0001 DC74_RS12520 3b8af8b505a8e4ba7295e966d1488b81 244 PANTHER PTHR10146:SF0 5 240 4.9E-68 T 23-04-2016 DC74_RS12520 3b8af8b505a8e4ba7295e966d1488b81 244 Gene3D G3DSA:3.20.20.10 3 241 5.7E-79 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS12520 3b8af8b505a8e4ba7295e966d1488b81 244 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 9 240 6.1E-44 T 23-04-2016 IPR011078 Uncharacterised protein family UPF0001 DC74_RS02260 11f48cd778dbbc39cef0d35e626c9c02 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 3.6E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS02260 11f48cd778dbbc39cef0d35e626c9c02 215 SUPERFAMILY SSF48498 91 202 1.11E-14 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS02260 11f48cd778dbbc39cef0d35e626c9c02 215 SUPERFAMILY SSF46689 19 79 3.85E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02260 11f48cd778dbbc39cef0d35e626c9c02 215 PANTHER PTHR30055 13 210 1.8E-24 T 23-04-2016 DC74_RS02260 11f48cd778dbbc39cef0d35e626c9c02 215 PANTHER PTHR30055:SF66 13 210 1.8E-24 T 23-04-2016 DC74_RS02260 11f48cd778dbbc39cef0d35e626c9c02 215 Gene3D G3DSA:1.10.357.10 73 202 9.7E-23 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS02260 11f48cd778dbbc39cef0d35e626c9c02 215 Gene3D G3DSA:1.10.10.60 17 72 5.6E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02260 11f48cd778dbbc39cef0d35e626c9c02 215 Pfam PF16859 Bacterial transcriptional repressor C-terminal 87 198 2.1E-23 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS31130 4b87b7d2765a9d8c83d23334588f6f57 286 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 252 272 2.1E-6 T 23-04-2016 IPR024726 Ferric iron reductase, C-terminal GO:0051537 DC74_RS35305 df45377da6d99cadb7bb36f6e352dcb6 303 SUPERFAMILY SSF52266 9 204 8.25E-32 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS35305 df45377da6d99cadb7bb36f6e352dcb6 303 PANTHER PTHR30383 1 255 1.4E-104 T 23-04-2016 DC74_RS35305 df45377da6d99cadb7bb36f6e352dcb6 303 PANTHER PTHR30383:SF8 1 255 1.4E-104 T 23-04-2016 DC74_RS35305 df45377da6d99cadb7bb36f6e352dcb6 303 Gene3D G3DSA:3.40.50.1110 10 205 2.5E-30 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS35305 df45377da6d99cadb7bb36f6e352dcb6 303 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 12 195 1.1E-17 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS19895 2023641e40724adc7a7fb95b6224e210 309 Gene3D G3DSA:3.30.530.20 1 160 7.7E-18 T 23-04-2016 IPR023393 START-like domain DC74_RS19895 2023641e40724adc7a7fb95b6224e210 309 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 7 64 8.1E-5 T 23-04-2016 IPR010419 Carbon monoxide dehydrogenase subunit G DC74_RS19895 2023641e40724adc7a7fb95b6224e210 309 SUPERFAMILY SSF55961 1 157 2.55E-13 T 23-04-2016 DC74_RS12370 fb669fc690787d7b683e14d0a36e8a7b 240 PANTHER PTHR21235:SF15 2 239 7.9E-88 T 23-04-2016 DC74_RS12370 fb669fc690787d7b683e14d0a36e8a7b 240 PANTHER PTHR21235 2 239 7.9E-88 T 23-04-2016 DC74_RS12370 fb669fc690787d7b683e14d0a36e8a7b 240 Gene3D G3DSA:3.20.20.70 5 238 3.6E-72 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS12370 fb669fc690787d7b683e14d0a36e8a7b 240 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 4 239 9.3E-119 T 23-04-2016 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 DC74_RS12370 fb669fc690787d7b683e14d0a36e8a7b 240 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 5 238 31.878 T 23-04-2016 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 DC74_RS12370 fb669fc690787d7b683e14d0a36e8a7b 240 SUPERFAMILY SSF51366 4 237 3.3E-63 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 DC74_RS12370 fb669fc690787d7b683e14d0a36e8a7b 240 Pfam PF00977 Histidine biosynthesis protein 6 231 1.6E-63 T 23-04-2016 IPR006062 Histidine biosynthesis GO:0000105 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 PRINTS PR00465 E-class P450 group IV signature 371 389 1.0E-16 T 23-04-2016 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 PRINTS PR00465 E-class P450 group IV signature 410 428 1.0E-16 T 23-04-2016 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 PRINTS PR00465 E-class P450 group IV signature 34 57 1.0E-16 T 23-04-2016 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 PRINTS PR00465 E-class P450 group IV signature 394 410 1.0E-16 T 23-04-2016 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 PRINTS PR00465 E-class P450 group IV signature 355 369 1.0E-16 T 23-04-2016 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 PANTHER PTHR24305 5 461 1.3E-81 T 23-04-2016 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 Gene3D G3DSA:1.10.630.10 9 461 4.8E-106 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 SUPERFAMILY SSF48264 7 461 1.57E-101 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 Pfam PF00067 Cytochrome P450 14 442 3.1E-76 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 PRINTS PR00385 P450 superfamily signature 327 338 2.3E-9 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 PRINTS PR00385 P450 superfamily signature 401 410 2.3E-9 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 PRINTS PR00385 P450 superfamily signature 410 421 2.3E-9 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 PRINTS PR00385 P450 superfamily signature 274 291 2.3E-9 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27045 41840881715c0f34e09d6dc7f22790d1 461 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 403 412 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS32300 197548f7814232c6e87544255e9d7563 418 SMART SM00825 Beta-ketoacyl synthase 5 404 8.2E-5 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS32300 197548f7814232c6e87544255e9d7563 418 PANTHER PTHR11712 6 404 1.6E-73 T 23-04-2016 DC74_RS32300 197548f7814232c6e87544255e9d7563 418 Gene3D G3DSA:3.40.47.10 6 257 1.7E-55 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS32300 197548f7814232c6e87544255e9d7563 418 Gene3D G3DSA:3.40.47.10 269 402 7.8E-36 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS32300 197548f7814232c6e87544255e9d7563 418 SUPERFAMILY SSF53901 212 402 8.06E-47 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS32300 197548f7814232c6e87544255e9d7563 418 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 361 3.2E-22 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS32300 197548f7814232c6e87544255e9d7563 418 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 243 3.3E-43 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS32300 197548f7814232c6e87544255e9d7563 418 SUPERFAMILY SSF53901 6 249 1.08E-59 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS25250 a3fdc740cea124d8a90df9294edb50b9 165 Pfam PF03449 Transcription elongation factor, N-terminal 10 79 1.7E-25 T 23-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 DC74_RS25250 a3fdc740cea124d8a90df9294edb50b9 165 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 10 160 3.2E-43 T 23-04-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 DC74_RS25250 a3fdc740cea124d8a90df9294edb50b9 165 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 22 53 - T 23-04-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 DC74_RS25250 a3fdc740cea124d8a90df9294edb50b9 165 PIRSF PIRSF006092 3 164 5.8E-34 T 23-04-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 DC74_RS25250 a3fdc740cea124d8a90df9294edb50b9 165 Hamap MF_00105 Transcription elongation factor GreA [greA]. 7 161 27.458 T 23-04-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 DC74_RS25250 a3fdc740cea124d8a90df9294edb50b9 165 SUPERFAMILY SSF54534 85 160 3.66E-9 T 23-04-2016 DC74_RS25250 a3fdc740cea124d8a90df9294edb50b9 165 PANTHER PTHR30437 2 159 3.1E-39 T 23-04-2016 DC74_RS25250 a3fdc740cea124d8a90df9294edb50b9 165 SUPERFAMILY SSF46557 8 81 1.44E-23 T 23-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 DC74_RS25250 a3fdc740cea124d8a90df9294edb50b9 165 Gene3D G3DSA:3.10.50.30 81 163 4.0E-13 T 23-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 DC74_RS25250 a3fdc740cea124d8a90df9294edb50b9 165 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 161 1.8E-11 T 23-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 DC74_RS25250 a3fdc740cea124d8a90df9294edb50b9 165 Gene3D G3DSA:1.10.287.180 7 79 2.6E-27 T 23-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 DC74_RS14920 952f671a80d1014b4f912c0a39e1c7b8 239 Pfam PF05099 Tellurite resistance protein TerB 84 227 2.4E-8 T 23-04-2016 IPR007791 Co-chaperone DjlA, N-terminal DC74_RS14920 952f671a80d1014b4f912c0a39e1c7b8 239 SUPERFAMILY SSF158682 155 231 1.57E-8 T 23-04-2016 IPR029024 TerB-like DC74_RS14920 952f671a80d1014b4f912c0a39e1c7b8 239 Gene3D G3DSA:1.10.3680.10 181 229 2.8E-6 T 23-04-2016 IPR029024 TerB-like DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 330 339 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 SUPERFAMILY SSF48264 9 388 5.63E-92 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 Gene3D G3DSA:1.10.630.10 8 389 3.3E-118 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 Pfam PF00067 Cytochrome P450 260 358 6.9E-20 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00385 P450 superfamily signature 227 244 3.0E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00385 P450 superfamily signature 328 337 3.0E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00385 P450 superfamily signature 337 348 3.0E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00385 P450 superfamily signature 262 273 3.0E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PANTHER PTHR11712 15 389 1.4E-86 T 23-04-2016 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00359 B-class P450 signature 132 148 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00359 B-class P450 signature 279 306 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00359 B-class P450 signature 85 96 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00359 B-class P450 signature 307 322 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00359 B-class P450 signature 262 273 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00359 B-class P450 signature 328 337 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00359 B-class P450 signature 337 348 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00359 B-class P450 signature 149 164 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06990 89c926d5403dd6d63bb33e63507eb533 390 PRINTS PR00359 B-class P450 signature 186 208 1.3E-58 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS31190 1f409c52d9ada8c64acb8596a54a41d0 333 SUPERFAMILY SSF46785 277 330 1.95E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31190 1f409c52d9ada8c64acb8596a54a41d0 333 Pfam PF12840 Helix-turn-helix domain 272 319 2.9E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31190 1f409c52d9ada8c64acb8596a54a41d0 333 SMART SM00418 262 333 0.0091 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS31190 1f409c52d9ada8c64acb8596a54a41d0 333 Gene3D G3DSA:1.10.10.10 277 327 8.7E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23525 c3610e44fe17b134eca2e4d4bad7673d 324 Gene3D G3DSA:3.90.550.10 35 175 1.4E-10 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS23525 c3610e44fe17b134eca2e4d4bad7673d 324 Pfam PF00535 Glycosyl transferase family 2 36 154 8.5E-8 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS23525 c3610e44fe17b134eca2e4d4bad7673d 324 SUPERFAMILY SSF53448 35 282 4.58E-55 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS23525 c3610e44fe17b134eca2e4d4bad7673d 324 PANTHER PTHR10859:SF99 13 219 5.3E-36 T 23-04-2016 DC74_RS23525 c3610e44fe17b134eca2e4d4bad7673d 324 PANTHER PTHR10859 13 219 5.3E-36 T 23-04-2016 DC74_RS22490 a997252a869106fbb6aef3e78ed53ae8 242 Gene3D G3DSA:1.10.3720.10 22 210 9.9E-30 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS22490 a997252a869106fbb6aef3e78ed53ae8 242 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 223 8.6E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS22490 a997252a869106fbb6aef3e78ed53ae8 242 SUPERFAMILY SSF161098 26 209 1.01E-34 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS22490 a997252a869106fbb6aef3e78ed53ae8 242 PANTHER PTHR30151 23 232 6.6E-59 T 23-04-2016 DC74_RS22490 a997252a869106fbb6aef3e78ed53ae8 242 PANTHER PTHR30151:SF23 23 232 6.6E-59 T 23-04-2016 DC74_RS37795 8e99a629b8c31da3ffca0078798dab9c 156 PANTHER PTHR11527:SF42 5 155 3.4E-28 T 23-04-2016 DC74_RS37795 8e99a629b8c31da3ffca0078798dab9c 156 SUPERFAMILY SSF49764 24 154 2.09E-31 T 23-04-2016 IPR008978 HSP20-like chaperone DC74_RS37795 8e99a629b8c31da3ffca0078798dab9c 156 Pfam PF00011 Hsp20/alpha crystallin family 58 155 8.5E-21 T 23-04-2016 IPR002068 Alpha crystallin/Hsp20 domain DC74_RS37795 8e99a629b8c31da3ffca0078798dab9c 156 PANTHER PTHR11527 5 155 3.4E-28 T 23-04-2016 IPR031107 Small heat shock protein HSP20 DC74_RS37795 8e99a629b8c31da3ffca0078798dab9c 156 Gene3D G3DSA:2.60.40.790 21 155 2.3E-32 T 23-04-2016 IPR008978 HSP20-like chaperone DC74_RS23130 8b5083e09cccdb82297d58b7d1b5e909 346 PANTHER PTHR30535 45 340 1.3E-134 T 23-04-2016 DC74_RS23130 8b5083e09cccdb82297d58b7d1b5e909 346 Gene3D G3DSA:3.40.50.1980 65 208 9.7E-10 T 23-04-2016 DC74_RS23130 8b5083e09cccdb82297d58b7d1b5e909 346 SUPERFAMILY SSF53807 65 340 8.24E-42 T 23-04-2016 DC74_RS23130 8b5083e09cccdb82297d58b7d1b5e909 346 PANTHER PTHR30535:SF7 45 340 1.3E-134 T 23-04-2016 DC74_RS23130 8b5083e09cccdb82297d58b7d1b5e909 346 Gene3D G3DSA:3.40.50.1980 211 340 1.4E-28 T 23-04-2016 DC74_RS23130 8b5083e09cccdb82297d58b7d1b5e909 346 Pfam PF01497 Periplasmic binding protein 68 319 2.0E-24 T 23-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 DC74_RS16360 f7d7d41c929657be6d13d40dc16eafa4 422 PANTHER PTHR30009:SF4 20 412 4.7E-157 T 23-04-2016 DC74_RS16360 f7d7d41c929657be6d13d40dc16eafa4 422 PANTHER PTHR30009 20 412 4.7E-157 T 23-04-2016 DC74_RS16360 f7d7d41c929657be6d13d40dc16eafa4 422 Pfam PF02378 Phosphotransferase system, EIIC 28 341 5.1E-76 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 DC74_RS03235 41b8c6e95d4b11f76281519c909b25fc 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.0E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03235 41b8c6e95d4b11f76281519c909b25fc 203 Pfam PF13977 Bacterial transcriptional repressor 85 194 2.8E-23 T 23-04-2016 DC74_RS03235 41b8c6e95d4b11f76281519c909b25fc 203 PANTHER PTHR30328:SF11 1 192 4.3E-32 T 23-04-2016 DC74_RS03235 41b8c6e95d4b11f76281519c909b25fc 203 Gene3D G3DSA:1.10.357.10 9 192 1.2E-36 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS03235 41b8c6e95d4b11f76281519c909b25fc 203 SUPERFAMILY SSF48498 82 193 3.62E-19 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS03235 41b8c6e95d4b11f76281519c909b25fc 203 SUPERFAMILY SSF46689 4 86 1.54E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03235 41b8c6e95d4b11f76281519c909b25fc 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 7.3E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03235 41b8c6e95d4b11f76281519c909b25fc 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 7.3E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03235 41b8c6e95d4b11f76281519c909b25fc 203 PANTHER PTHR30328 1 192 4.3E-32 T 23-04-2016 DC74_RS32405 0ca7a7861419b5424a0dc0b4d626972d 382 Gene3D G3DSA:3.40.50.2000 218 363 3.6E-19 T 23-04-2016 DC74_RS32405 0ca7a7861419b5424a0dc0b4d626972d 382 Pfam PF06722 Protein of unknown function (DUF1205) 174 268 1.6E-16 T 23-04-2016 IPR010610 Domain of unknown function DUF1205 DC74_RS32405 0ca7a7861419b5424a0dc0b4d626972d 382 SUPERFAMILY SSF53756 1 381 1.2E-62 T 23-04-2016 DC74_RS32405 0ca7a7861419b5424a0dc0b4d626972d 382 Gene3D G3DSA:3.40.50.2000 1 217 1.4E-15 T 23-04-2016 DC74_RS07525 6d1f843d4d7cf0d46c07400a3bceec39 655 Pfam PF00005 ABC transporter 397 546 3.3E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS07525 6d1f843d4d7cf0d46c07400a3bceec39 655 Gene3D G3DSA:1.20.1560.10 30 350 2.1E-71 T 23-04-2016 DC74_RS07525 6d1f843d4d7cf0d46c07400a3bceec39 655 PANTHER PTHR24221 392 625 7.0E-206 T 23-04-2016 DC74_RS07525 6d1f843d4d7cf0d46c07400a3bceec39 655 PANTHER PTHR24221 18 372 7.0E-206 T 23-04-2016 DC74_RS07525 6d1f843d4d7cf0d46c07400a3bceec39 655 SUPERFAMILY SSF90123 30 350 6.02E-71 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS07525 6d1f843d4d7cf0d46c07400a3bceec39 655 SMART SM00382 406 592 3.1E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS07525 6d1f843d4d7cf0d46c07400a3bceec39 655 SUPERFAMILY SSF52540 361 617 4.37E-82 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07525 6d1f843d4d7cf0d46c07400a3bceec39 655 Pfam PF00664 ABC transporter transmembrane region 47 314 3.5E-40 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS07525 6d1f843d4d7cf0d46c07400a3bceec39 655 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS07525 6d1f843d4d7cf0d46c07400a3bceec39 655 Gene3D G3DSA:3.40.50.300 362 610 1.4E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34150 f88924dfc0664d07c69fcceff30156b5 143 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 9 139 1.1E-42 T 23-04-2016 IPR019920 F420-binding domain, putative DC74_RS34150 f88924dfc0664d07c69fcceff30156b5 143 PANTHER PTHR35176:SF2 1 142 8.4E-67 T 23-04-2016 DC74_RS34150 f88924dfc0664d07c69fcceff30156b5 143 Gene3D G3DSA:2.30.110.10 9 140 1.3E-26 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS34150 f88924dfc0664d07c69fcceff30156b5 143 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 89 1.3E-14 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS34150 f88924dfc0664d07c69fcceff30156b5 143 PANTHER PTHR35176 1 142 8.4E-67 T 23-04-2016 DC74_RS34150 f88924dfc0664d07c69fcceff30156b5 143 SUPERFAMILY SSF50475 9 140 1.37E-34 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS31740 872bc1adef7f6f3595f6285839d2e1bf 374 SUPERFAMILY SSF110738 1 371 1.7E-113 T 23-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 DC74_RS31740 872bc1adef7f6f3595f6285839d2e1bf 374 Pfam PF02595 Glycerate kinase family 1 371 1.2E-129 T 23-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 DC74_RS31740 872bc1adef7f6f3595f6285839d2e1bf 374 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 1 370 3.4E-119 T 23-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 DC74_RS31740 872bc1adef7f6f3595f6285839d2e1bf 374 PANTHER PTHR21599 1 370 2.8E-128 T 23-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 DC74_RS31740 872bc1adef7f6f3595f6285839d2e1bf 374 Gene3D G3DSA:3.90.1510.10 40 274 5.9E-86 T 23-04-2016 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 DC74_RS31740 872bc1adef7f6f3595f6285839d2e1bf 374 PANTHER PTHR21599:SF0 1 370 2.8E-128 T 23-04-2016 DC74_RS31740 872bc1adef7f6f3595f6285839d2e1bf 374 PIRSF PIRSF006078 1 374 2.1E-120 T 23-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 Gene3D G3DSA:2.140.10.10 556 606 4.2E-4 T 23-04-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 Gene3D G3DSA:2.140.10.10 385 555 2.8E-14 T 23-04-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 SUPERFAMILY SSF50998 336 584 8.77E-16 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 SUPERFAMILY SSF56112 11 261 7.79E-55 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 SMART SM00220 15 265 1.7E-33 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 Gene3D G3DSA:1.10.510.10 98 261 6.9E-32 T 23-04-2016 DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 Gene3D G3DSA:3.30.200.20 8 93 6.2E-14 T 23-04-2016 DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 PANTHER PTHR24362:SF160 2 268 4.2E-69 T 23-04-2016 DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 Pfam PF00069 Protein kinase domain 15 259 1.4E-31 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 Pfam PF13360 PQQ-like domain 432 601 6.0E-13 T 23-04-2016 IPR002372 Pyrrolo-quinoline quinone repeat DC74_RS36970 cbdbf48689412b7b00d712b7029c2ed7 696 PANTHER PTHR24362 2 268 4.2E-69 T 23-04-2016 DC74_RS32460 f1eba9a8c15a074166afa141d2272c5c 125 SUPERFAMILY SSF103196 2 122 3.84E-26 T 23-04-2016 DC74_RS32460 f1eba9a8c15a074166afa141d2272c5c 125 PANTHER PTHR36222 1 124 4.8E-37 T 23-04-2016 DC74_RS32460 f1eba9a8c15a074166afa141d2272c5c 125 Pfam PF03259 Roadblock/LC7 domain 1 93 3.0E-22 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS32460 f1eba9a8c15a074166afa141d2272c5c 125 SMART SM00960 2 93 5.7E-22 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS32460 f1eba9a8c15a074166afa141d2272c5c 125 Gene3D G3DSA:3.30.450.30 1 120 6.4E-22 T 23-04-2016 DC74_RS29605 85c1f6c9552a9e96968e31cdac06f52c 390 Pfam PF08007 Cupin superfamily protein 30 267 9.5E-45 T 23-04-2016 IPR003347 JmjC domain DC74_RS29605 85c1f6c9552a9e96968e31cdac06f52c 390 Gene3D G3DSA:2.60.120.650 30 223 5.4E-33 T 23-04-2016 DC74_RS29605 85c1f6c9552a9e96968e31cdac06f52c 390 SMART SM00558 97 235 4.0E-5 T 23-04-2016 IPR003347 JmjC domain DC74_RS29605 85c1f6c9552a9e96968e31cdac06f52c 390 SUPERFAMILY SSF51197 30 276 4.26E-44 T 23-04-2016 DC74_RS29605 85c1f6c9552a9e96968e31cdac06f52c 390 PANTHER PTHR13096 84 219 1.1E-24 T 23-04-2016 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 PIRSF PIRSF000804 1 375 7.1E-94 T 23-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 SUPERFAMILY SSF55979 249 374 5.23E-29 T 23-04-2016 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 SUPERFAMILY SSF55979 2 118 8.53E-24 T 23-04-2016 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 373 5.9E-35 T 23-04-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 SMART SM00480 17 370 2.1E-139 T 23-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 118 4.4E-38 T 23-04-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 246 2.2E-31 T 23-04-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 Gene3D G3DSA:3.10.150.10 2 120 7.4E-31 T 23-04-2016 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 Gene3D G3DSA:3.10.150.10 126 250 3.7E-29 T 23-04-2016 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 2.7E-89 T 23-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 Gene3D G3DSA:3.10.150.10 252 374 3.4E-37 T 23-04-2016 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 PANTHER PTHR30478 2 376 3.5E-116 T 23-04-2016 DC74_RS20685 f5384b5762d3cab1020ddf1d392d3cdc 376 SUPERFAMILY SSF55979 126 249 1.05E-18 T 23-04-2016 DC74_RS31415 b3d53804e6d7c99faba3f4326af320a5 267 SMART SM00346 22 109 3.6E-22 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS31415 b3d53804e6d7c99faba3f4326af320a5 267 PANTHER PTHR30136:SF3 16 261 3.1E-95 T 23-04-2016 DC74_RS31415 b3d53804e6d7c99faba3f4326af320a5 267 Gene3D G3DSA:3.30.450.40 96 261 5.1E-61 T 23-04-2016 IPR029016 GAF domain-like DC74_RS31415 b3d53804e6d7c99faba3f4326af320a5 267 Gene3D G3DSA:1.10.10.10 20 94 3.1E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31415 b3d53804e6d7c99faba3f4326af320a5 267 SUPERFAMILY SSF46785 22 92 4.37E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31415 b3d53804e6d7c99faba3f4326af320a5 267 Pfam PF01614 Bacterial transcriptional regulator 137 259 3.2E-32 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS31415 b3d53804e6d7c99faba3f4326af320a5 267 SUPERFAMILY SSF55781 79 261 3.2E-51 T 23-04-2016 IPR029016 GAF domain-like DC74_RS31415 b3d53804e6d7c99faba3f4326af320a5 267 PANTHER PTHR30136 16 261 3.1E-95 T 23-04-2016 DC74_RS31415 b3d53804e6d7c99faba3f4326af320a5 267 Pfam PF09339 IclR helix-turn-helix domain 24 75 6.1E-18 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 PANTHER PTHR24423 381 419 2.9E-92 T 23-04-2016 DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 PANTHER PTHR24423:SF468 478 689 2.9E-92 T 23-04-2016 DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 572 678 1.9E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 Pfam PF00672 HAMP domain 368 453 1.3E-18 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 Pfam PF08376 Nitrate and nitrite sensing 103 349 6.6E-40 T 23-04-2016 IPR013587 Nitrate/nitrite sensing protein DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 PANTHER PTHR24423 437 453 2.9E-92 T 23-04-2016 DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 PANTHER PTHR24423 478 689 2.9E-92 T 23-04-2016 DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 PANTHER PTHR24423:SF468 437 453 2.9E-92 T 23-04-2016 DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 SUPERFAMILY SSF55874 556 677 1.44E-18 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 PANTHER PTHR24423:SF468 381 419 2.9E-92 T 23-04-2016 DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 SMART SM00304 387 457 3.6E-5 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 Gene3D G3DSA:3.30.565.10 536 681 2.6E-16 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27850 ca2248aba3ffada54794a4eebb5cda50 1218 SMART SM00387 569 680 1.2E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 SUPERFAMILY SSF46785 12 79 5.37E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 SMART SM00345 17 75 1.4E-10 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 6.5E-10 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 6.5E-10 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 SUPERFAMILY SSF64288 63 237 4.4E-24 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 Gene3D G3DSA:3.40.1410.10 106 236 8.5E-20 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 PANTHER PTHR11751 12 78 2.1E-19 T 23-04-2016 DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 PANTHER PTHR11751:SF333 122 145 2.1E-19 T 23-04-2016 DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 SMART SM00866 93 234 1.5E-7 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 Gene3D G3DSA:1.10.10.10 10 79 3.3E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 Pfam PF07702 UTRA domain 105 232 1.5E-14 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 PANTHER PTHR11751:SF333 12 78 2.1E-19 T 23-04-2016 DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 75 3.4E-15 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS35275 a517decfcb0a18ec56907bc3d8f6aff6 248 PANTHER PTHR11751 122 145 2.1E-19 T 23-04-2016 DC74_RS32040 abb028368d3cf8e38b3a7e13f2f7b90b 645 SMART SM00282 476 611 1.4E-9 T 23-04-2016 IPR001791 Laminin G domain DC74_RS32040 abb028368d3cf8e38b3a7e13f2f7b90b 645 PANTHER PTHR10628 53 554 1.7E-116 T 23-04-2016 IPR026856 Sialidase family GO:0004308 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 DC74_RS32040 abb028368d3cf8e38b3a7e13f2f7b90b 645 Gene3D G3DSA:2.60.120.200 444 619 4.0E-25 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS32040 abb028368d3cf8e38b3a7e13f2f7b90b 645 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 457 618 1.7E-22 T 23-04-2016 DC74_RS32040 abb028368d3cf8e38b3a7e13f2f7b90b 645 Pfam PF13088 BNR repeat-like domain 79 368 4.9E-31 T 23-04-2016 IPR011040 Sialidases DC74_RS32040 abb028368d3cf8e38b3a7e13f2f7b90b 645 SUPERFAMILY SSF50939 54 417 2.35E-84 T 23-04-2016 IPR011040 Sialidases DC74_RS32040 abb028368d3cf8e38b3a7e13f2f7b90b 645 PANTHER PTHR10628:SF5 53 554 1.7E-116 T 23-04-2016 DC74_RS32040 abb028368d3cf8e38b3a7e13f2f7b90b 645 SMART SM00560 476 616 4.4E-17 T 23-04-2016 IPR006558 LamG-like jellyroll fold DC74_RS32040 abb028368d3cf8e38b3a7e13f2f7b90b 645 SUPERFAMILY SSF49899 416 619 3.35E-29 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS32040 abb028368d3cf8e38b3a7e13f2f7b90b 645 Gene3D G3DSA:2.120.10.10 61 417 1.1E-82 T 23-04-2016 IPR011040 Sialidases DC74_RS33835 7674700f7ad299a3d12f136bd9b64570 209 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 197 1.1E-57 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS33835 7674700f7ad299a3d12f136bd9b64570 209 Gene3D G3DSA:3.40.50.1240 3 204 9.7E-58 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS33835 7674700f7ad299a3d12f136bd9b64570 209 SUPERFAMILY SSF53254 3 204 1.52E-57 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS33835 7674700f7ad299a3d12f136bd9b64570 209 PANTHER PTHR23029 6 209 6.5E-45 T 23-04-2016 DC74_RS33835 7674700f7ad299a3d12f136bd9b64570 209 SMART SM00855 3 157 2.6E-22 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS06670 068822c560e3bb18a811c6426240189e 127 Pfam PF01022 Bacterial regulatory protein, arsR family 35 79 7.3E-14 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS06670 068822c560e3bb18a811c6426240189e 127 Gene3D G3DSA:1.10.10.10 6 109 7.2E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06670 068822c560e3bb18a811c6426240189e 127 PANTHER PTHR33154 22 117 1.6E-24 T 23-04-2016 DC74_RS06670 068822c560e3bb18a811c6426240189e 127 SUPERFAMILY SSF46785 18 107 1.75E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06670 068822c560e3bb18a811c6426240189e 127 SMART SM00418 27 105 3.0E-27 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS06670 068822c560e3bb18a811c6426240189e 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 44 1.7E-11 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS06670 068822c560e3bb18a811c6426240189e 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 76 91 1.7E-11 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS06670 068822c560e3bb18a811c6426240189e 127 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 1.7E-11 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS17440 fa3a622a9648e9e42cd99f9616261d91 486 Pfam PF09852 Predicted membrane protein (DUF2079) 63 447 9.2E-60 T 23-04-2016 IPR018650 Sulfolobus virus STSV1, Orf64 DC74_RS27780 30fc44f6fefdd66bfb349491578620d6 536 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 20 36 - T 23-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS27780 30fc44f6fefdd66bfb349491578620d6 536 PANTHER PTHR10277:SF5 9 535 6.0E-253 T 23-04-2016 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101|UniPathway: UPA00047 DC74_RS27780 30fc44f6fefdd66bfb349491578620d6 536 SUPERFAMILY SSF110921 408 522 1.44E-19 T 23-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS27780 30fc44f6fefdd66bfb349491578620d6 536 PANTHER PTHR10277 9 535 6.0E-253 T 23-04-2016 DC74_RS27780 30fc44f6fefdd66bfb349491578620d6 536 SMART SM00917 384 527 5.2E-37 T 23-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS27780 30fc44f6fefdd66bfb349491578620d6 536 Pfam PF00682 HMGL-like 14 282 4.8E-43 T 23-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 DC74_RS27780 30fc44f6fefdd66bfb349491578620d6 536 SUPERFAMILY SSF51569 9 301 6.78E-73 T 23-04-2016 DC74_RS27780 30fc44f6fefdd66bfb349491578620d6 536 Gene3D G3DSA:3.20.20.70 5 358 7.8E-110 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS27780 30fc44f6fefdd66bfb349491578620d6 536 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 14 530 2.5E-185 T 23-04-2016 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101|UniPathway: UPA00047 DC74_RS27780 30fc44f6fefdd66bfb349491578620d6 536 Pfam PF08502 LeuA allosteric (dimerisation) domain 384 525 4.0E-26 T 23-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS07515 c69b2b403cf9c5c281462a1ea04cc271 162 Gene3D G3DSA:3.40.30.10 1 161 2.5E-62 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS07515 c69b2b403cf9c5c281462a1ea04cc271 162 PRINTS PR01011 Glutathione peroxidase family signature 21 38 4.7E-19 T 23-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 DC74_RS07515 c69b2b403cf9c5c281462a1ea04cc271 162 PRINTS PR01011 Glutathione peroxidase family signature 56 72 4.7E-19 T 23-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 DC74_RS07515 c69b2b403cf9c5c281462a1ea04cc271 162 PRINTS PR01011 Glutathione peroxidase family signature 122 131 4.7E-19 T 23-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 DC74_RS07515 c69b2b403cf9c5c281462a1ea04cc271 162 PANTHER PTHR11592 2 162 6.4E-75 T 23-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 DC74_RS07515 c69b2b403cf9c5c281462a1ea04cc271 162 PIRSF PIRSF000303 1 162 2.6E-61 T 23-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 DC74_RS07515 c69b2b403cf9c5c281462a1ea04cc271 162 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 23-04-2016 IPR029760 Glutathione peroxidase conserved site DC74_RS07515 c69b2b403cf9c5c281462a1ea04cc271 162 SUPERFAMILY SSF52833 1 160 5.38E-56 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS07515 c69b2b403cf9c5c281462a1ea04cc271 162 PANTHER PTHR11592:SF40 2 162 6.4E-75 T 23-04-2016 DC74_RS07515 c69b2b403cf9c5c281462a1ea04cc271 162 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 23-04-2016 IPR029759 Glutathione peroxidase active site DC74_RS07515 c69b2b403cf9c5c281462a1ea04cc271 162 Pfam PF00255 Glutathione peroxidase 3 109 7.2E-39 T 23-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 DC74_RS14010 97247ffd1c3d907e2df97ac2212d02dd 171 PANTHER PTHR30204 42 163 9.7E-58 T 23-04-2016 DC74_RS14010 97247ffd1c3d907e2df97ac2212d02dd 171 ProSitePatterns PS00552 MerR-type HTH domain signature. 53 75 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS14010 97247ffd1c3d907e2df97ac2212d02dd 171 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 62 75 3.4E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS14010 97247ffd1c3d907e2df97ac2212d02dd 171 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 51 62 3.4E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS14010 97247ffd1c3d907e2df97ac2212d02dd 171 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 86 106 3.4E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS14010 97247ffd1c3d907e2df97ac2212d02dd 171 SUPERFAMILY SSF46955 50 164 2.53E-30 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS14010 97247ffd1c3d907e2df97ac2212d02dd 171 PANTHER PTHR30204:SF2 42 163 9.7E-58 T 23-04-2016 DC74_RS14010 97247ffd1c3d907e2df97ac2212d02dd 171 Pfam PF13411 MerR HTH family regulatory protein 50 111 3.4E-16 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS14010 97247ffd1c3d907e2df97ac2212d02dd 171 Gene3D G3DSA:1.10.1660.10 50 166 4.5E-32 T 23-04-2016 DC74_RS14010 97247ffd1c3d907e2df97ac2212d02dd 171 SMART SM00422 50 119 4.1E-18 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS11310 071aa410badf7a903beef7bc1010017d 233 PANTHER PTHR11751:SF342 7 111 1.5E-50 T 23-04-2016 DC74_RS11310 071aa410badf7a903beef7bc1010017d 233 SUPERFAMILY SSF46785 7 78 3.73E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11310 071aa410badf7a903beef7bc1010017d 233 Gene3D G3DSA:1.10.10.10 8 77 4.0E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11310 071aa410badf7a903beef7bc1010017d 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.4E-9 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS11310 071aa410badf7a903beef7bc1010017d 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.4E-9 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS11310 071aa410badf7a903beef7bc1010017d 233 SMART SM00895 95 218 1.0E-17 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS11310 071aa410badf7a903beef7bc1010017d 233 PANTHER PTHR11751 7 111 1.5E-50 T 23-04-2016 DC74_RS11310 071aa410badf7a903beef7bc1010017d 233 SUPERFAMILY SSF48008 92 215 6.8E-24 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS11310 071aa410badf7a903beef7bc1010017d 233 Gene3D G3DSA:1.20.120.530 91 215 2.7E-25 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS11310 071aa410badf7a903beef7bc1010017d 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 5.4E-20 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS11310 071aa410badf7a903beef7bc1010017d 233 Pfam PF07729 FCD domain 97 215 1.6E-22 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS11310 071aa410badf7a903beef7bc1010017d 233 SMART SM00345 15 74 1.4E-19 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS08380 0c1a1fa0d39f68f60b354a1f80185f85 393 PIRSF PIRSF000429 5 383 2.5E-18 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS08380 0c1a1fa0d39f68f60b354a1f80185f85 393 Gene3D G3DSA:3.40.47.10 19 123 3.9E-15 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS08380 0c1a1fa0d39f68f60b354a1f80185f85 393 Gene3D G3DSA:3.40.47.10 201 225 3.9E-15 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS08380 0c1a1fa0d39f68f60b354a1f80185f85 393 PANTHER PTHR18919:SF8 8 390 1.8E-78 T 23-04-2016 DC74_RS08380 0c1a1fa0d39f68f60b354a1f80185f85 393 Gene3D G3DSA:3.40.47.10 268 376 2.9E-5 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS08380 0c1a1fa0d39f68f60b354a1f80185f85 393 SUPERFAMILY SSF53901 195 383 8.95E-24 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS08380 0c1a1fa0d39f68f60b354a1f80185f85 393 SUPERFAMILY SSF53901 8 127 8.95E-24 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS08380 0c1a1fa0d39f68f60b354a1f80185f85 393 PANTHER PTHR18919 8 390 1.8E-78 T 23-04-2016 DC74_RS37115 18cbbc46ec41e62cf2257de67da844e1 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.6E-13 T 23-04-2016 DC74_RS37115 18cbbc46ec41e62cf2257de67da844e1 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.6E-13 T 23-04-2016 DC74_RS37115 18cbbc46ec41e62cf2257de67da844e1 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 1.6E-13 T 23-04-2016 DC74_RS37115 18cbbc46ec41e62cf2257de67da844e1 380 Gene3D G3DSA:3.50.50.60 2 173 1.1E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37115 18cbbc46ec41e62cf2257de67da844e1 380 Gene3D G3DSA:3.50.50.60 276 351 1.1E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37115 18cbbc46ec41e62cf2257de67da844e1 380 PANTHER PTHR13789 1 375 4.0E-121 T 23-04-2016 DC74_RS37115 18cbbc46ec41e62cf2257de67da844e1 380 PANTHER PTHR13789:SF174 1 375 4.0E-121 T 23-04-2016 DC74_RS37115 18cbbc46ec41e62cf2257de67da844e1 380 SUPERFAMILY SSF51905 3 168 4.58E-47 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37115 18cbbc46ec41e62cf2257de67da844e1 380 SUPERFAMILY SSF51905 275 366 4.58E-47 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37115 18cbbc46ec41e62cf2257de67da844e1 380 Pfam PF01494 FAD binding domain 3 346 1.5E-17 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS10955 283fddc57243ca8c371311263f66d842 384 PANTHER PTHR12468:SF3 44 208 8.7E-56 T 23-04-2016 DC74_RS10955 283fddc57243ca8c371311263f66d842 384 Pfam PF04188 Mannosyltransferase (PIG-V) 48 189 3.3E-5 T 23-04-2016 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 KEGG: 00051+2.4.1.-|KEGG: 00512+2.4.1.-|KEGG: 00513+2.4.1.-|KEGG: 00514+2.4.1.-|KEGG: 00522+2.4.1.-|KEGG: 00533+2.4.1.-|KEGG: 00540+2.4.1.-|KEGG: 00550+2.4.1.-|KEGG: 00561+2.4.1.-|KEGG: 00563+2.4.1.-|KEGG: 00600+2.4.1.-|KEGG: 00601+2.4.1.-|KEGG: 00603+2.4.1.-|KEGG: 00604+2.4.1.-|KEGG: 00906+2.4.1.-|KEGG: 00908+2.4.1.-|KEGG: 00941+2.4.1.-|KEGG: 00942+2.4.1.-|KEGG: 00944+2.4.1.-|KEGG: 00945+2.4.1.-|KEGG: 00965+2.4.1.-|UniPathway: UPA00196 DC74_RS10955 283fddc57243ca8c371311263f66d842 384 PANTHER PTHR12468 44 208 8.7E-56 T 23-04-2016 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 KEGG: 00051+2.4.1.-|KEGG: 00512+2.4.1.-|KEGG: 00513+2.4.1.-|KEGG: 00514+2.4.1.-|KEGG: 00522+2.4.1.-|KEGG: 00533+2.4.1.-|KEGG: 00540+2.4.1.-|KEGG: 00550+2.4.1.-|KEGG: 00561+2.4.1.-|KEGG: 00563+2.4.1.-|KEGG: 00600+2.4.1.-|KEGG: 00601+2.4.1.-|KEGG: 00603+2.4.1.-|KEGG: 00604+2.4.1.-|KEGG: 00906+2.4.1.-|KEGG: 00908+2.4.1.-|KEGG: 00941+2.4.1.-|KEGG: 00942+2.4.1.-|KEGG: 00944+2.4.1.-|KEGG: 00945+2.4.1.-|KEGG: 00965+2.4.1.-|UniPathway: UPA00196 DC74_RS10150 9b190d7e6ae638f1eca5f0014c260a23 457 SUPERFAMILY SSF53720 5 450 5.63E-150 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS10150 9b190d7e6ae638f1eca5f0014c260a23 457 PANTHER PTHR11699:SF46 3 450 1.4E-202 T 23-04-2016 DC74_RS10150 9b190d7e6ae638f1eca5f0014c260a23 457 Gene3D G3DSA:3.40.309.10 244 428 1.5E-57 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS10150 9b190d7e6ae638f1eca5f0014c260a23 457 PANTHER PTHR11699 3 450 1.4E-202 T 23-04-2016 DC74_RS10150 9b190d7e6ae638f1eca5f0014c260a23 457 Pfam PF00171 Aldehyde dehydrogenase family 5 448 5.0E-158 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS10150 9b190d7e6ae638f1eca5f0014c260a23 457 Gene3D G3DSA:3.40.605.10 5 243 2.9E-89 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS10150 9b190d7e6ae638f1eca5f0014c260a23 457 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 229 236 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS10150 9b190d7e6ae638f1eca5f0014c260a23 457 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 257 268 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS09050 668d3d48cd5ccfdec7ec145070c4c2a1 222 Gene3D G3DSA:3.40.50.300 7 198 1.8E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09050 668d3d48cd5ccfdec7ec145070c4c2a1 222 Pfam PF00005 ABC transporter 7 139 3.3E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS09050 668d3d48cd5ccfdec7ec145070c4c2a1 222 SMART SM00382 2 186 1.2E-7 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS09050 668d3d48cd5ccfdec7ec145070c4c2a1 222 SUPERFAMILY SSF52540 7 197 1.78E-48 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09050 668d3d48cd5ccfdec7ec145070c4c2a1 222 PANTHER PTHR24220 7 194 6.9E-59 T 23-04-2016 DC74_RS09050 668d3d48cd5ccfdec7ec145070c4c2a1 222 ProSitePatterns PS00211 ABC transporters family signature. 111 125 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS36360 a3e4002fe8f52a456e1aba3cbf465b04 365 SUPERFAMILY SSF51412 18 262 1.25E-60 T 23-04-2016 DC74_RS36360 a3e4002fe8f52a456e1aba3cbf465b04 365 SUPERFAMILY SSF51412 322 361 1.25E-60 T 23-04-2016 DC74_RS36360 a3e4002fe8f52a456e1aba3cbf465b04 365 PANTHER PTHR32332:SF20 18 251 3.2E-112 T 23-04-2016 DC74_RS36360 a3e4002fe8f52a456e1aba3cbf465b04 365 PANTHER PTHR32332:SF20 286 361 3.2E-112 T 23-04-2016 DC74_RS36360 a3e4002fe8f52a456e1aba3cbf465b04 365 Gene3D G3DSA:3.20.20.70 323 349 2.1E-69 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS36360 a3e4002fe8f52a456e1aba3cbf465b04 365 Gene3D G3DSA:3.20.20.70 17 290 2.1E-69 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS36360 a3e4002fe8f52a456e1aba3cbf465b04 365 Pfam PF03060 Nitronate monooxygenase 21 354 5.4E-92 T 23-04-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 DC74_RS36360 a3e4002fe8f52a456e1aba3cbf465b04 365 PANTHER PTHR32332 18 251 3.2E-112 T 23-04-2016 DC74_RS36360 a3e4002fe8f52a456e1aba3cbf465b04 365 PANTHER PTHR32332 286 361 3.2E-112 T 23-04-2016 DC74_RS18025 7598f55ee94551e09158c0c84d61ad44 509 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS18025 7598f55ee94551e09158c0c84d61ad44 509 Pfam PF07690 Major Facilitator Superfamily 19 414 2.8E-53 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS18025 7598f55ee94551e09158c0c84d61ad44 509 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 16 442 3.1E-75 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS18025 7598f55ee94551e09158c0c84d61ad44 509 Gene3D G3DSA:1.20.1250.20 272 477 2.7E-14 T 23-04-2016 DC74_RS18025 7598f55ee94551e09158c0c84d61ad44 509 Gene3D G3DSA:1.20.1250.20 10 197 1.1E-29 T 23-04-2016 DC74_RS18025 7598f55ee94551e09158c0c84d61ad44 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 5.6E-7 T 23-04-2016 DC74_RS18025 7598f55ee94551e09158c0c84d61ad44 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 5.6E-7 T 23-04-2016 DC74_RS18025 7598f55ee94551e09158c0c84d61ad44 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 206 224 5.6E-7 T 23-04-2016 DC74_RS18025 7598f55ee94551e09158c0c84d61ad44 509 SUPERFAMILY SSF103473 8 199 9.16E-67 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS18025 7598f55ee94551e09158c0c84d61ad44 509 SUPERFAMILY SSF103473 251 474 9.16E-67 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS18025 7598f55ee94551e09158c0c84d61ad44 509 PANTHER PTHR23501:SF69 11 479 1.2E-186 T 23-04-2016 DC74_RS18025 7598f55ee94551e09158c0c84d61ad44 509 PANTHER PTHR23501 11 479 1.2E-186 T 23-04-2016 DC74_RS21810 c9387efb9d8ce5ea12dcb1a04dbed74a 266 Pfam PF07702 UTRA domain 113 254 1.4E-26 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS21810 c9387efb9d8ce5ea12dcb1a04dbed74a 266 Gene3D G3DSA:3.40.1410.10 90 261 1.3E-31 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS21810 c9387efb9d8ce5ea12dcb1a04dbed74a 266 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 92 1.4E-16 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS21810 c9387efb9d8ce5ea12dcb1a04dbed74a 266 Gene3D G3DSA:1.10.10.10 29 89 1.2E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21810 c9387efb9d8ce5ea12dcb1a04dbed74a 266 SUPERFAMILY SSF64288 80 261 2.2E-36 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS21810 c9387efb9d8ce5ea12dcb1a04dbed74a 266 SMART SM00866 112 255 2.9E-22 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS21810 c9387efb9d8ce5ea12dcb1a04dbed74a 266 PANTHER PTHR11751 140 164 8.4E-17 T 23-04-2016 DC74_RS21810 c9387efb9d8ce5ea12dcb1a04dbed74a 266 PANTHER PTHR11751 48 94 8.4E-17 T 23-04-2016 DC74_RS21810 c9387efb9d8ce5ea12dcb1a04dbed74a 266 SUPERFAMILY SSF46785 27 96 9.87E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21810 c9387efb9d8ce5ea12dcb1a04dbed74a 266 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 66 1.7E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS21810 c9387efb9d8ce5ea12dcb1a04dbed74a 266 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 66 82 1.7E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS21810 c9387efb9d8ce5ea12dcb1a04dbed74a 266 SMART SM00345 34 92 6.7E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS39605 26ad3589e393445e330a561b1f7adb60 319 Gene3D G3DSA:3.40.50.1820 20 258 1.1E-25 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS39605 26ad3589e393445e330a561b1f7adb60 319 Pfam PF07224 Chlorophyllase 34 156 1.9E-6 T 23-04-2016 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164|UniPathway: UPA00674 DC74_RS39605 26ad3589e393445e330a561b1f7adb60 319 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 21 55 - T 23-04-2016 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 DC74_RS39605 26ad3589e393445e330a561b1f7adb60 319 PANTHER PTHR10272 29 256 3.7E-21 T 23-04-2016 IPR005065 Platelet-activating factor acetylhydrolase GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 DC74_RS39605 26ad3589e393445e330a561b1f7adb60 319 SUPERFAMILY SSF53474 4 288 1.59E-23 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02600 0a96093a26e390b25878fa823a9c21ec 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 1.5E-9 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS02600 0a96093a26e390b25878fa823a9c21ec 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 210 224 1.5E-9 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS02600 0a96093a26e390b25878fa823a9c21ec 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 1.5E-9 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS02600 0a96093a26e390b25878fa823a9c21ec 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.5E-9 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS02600 0a96093a26e390b25878fa823a9c21ec 267 SUPERFAMILY SSF53474 3 264 1.46E-56 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02600 0a96093a26e390b25878fa823a9c21ec 267 Gene3D G3DSA:3.40.50.1820 6 265 4.1E-60 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02600 0a96093a26e390b25878fa823a9c21ec 267 Pfam PF12697 Alpha/beta hydrolase family 29 259 9.0E-21 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS02600 0a96093a26e390b25878fa823a9c21ec 267 PANTHER PTHR10992 197 266 3.5E-50 T 23-04-2016 DC74_RS02600 0a96093a26e390b25878fa823a9c21ec 267 PANTHER PTHR10992 6 136 3.5E-50 T 23-04-2016 DC74_RS02600 0a96093a26e390b25878fa823a9c21ec 267 PANTHER PTHR10992 153 181 3.5E-50 T 23-04-2016 DC74_RS25830 50e2a6cf8b332083598e1ae5b924cb2c 344 Pfam PF00005 ABC transporter 36 187 2.4E-34 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS25830 50e2a6cf8b332083598e1ae5b924cb2c 344 PANTHER PTHR24220:SF336 9 313 2.8E-168 T 23-04-2016 DC74_RS25830 50e2a6cf8b332083598e1ae5b924cb2c 344 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS25830 50e2a6cf8b332083598e1ae5b924cb2c 344 SUPERFAMILY SSF52540 7 259 1.82E-77 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25830 50e2a6cf8b332083598e1ae5b924cb2c 344 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 306 1.2E-16 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS25830 50e2a6cf8b332083598e1ae5b924cb2c 344 SMART SM00382 44 237 1.6E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS25830 50e2a6cf8b332083598e1ae5b924cb2c 344 PANTHER PTHR24220 9 313 2.8E-168 T 23-04-2016 DC74_RS25830 50e2a6cf8b332083598e1ae5b924cb2c 344 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 315 6.2E-24 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS25830 50e2a6cf8b332083598e1ae5b924cb2c 344 Gene3D G3DSA:3.40.50.300 6 261 2.0E-86 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS37175 b773a1b38f97e803bca2e2598e23f6f5 197 Pfam PF00484 Carbonic anhydrase 29 184 1.8E-30 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS37175 b773a1b38f97e803bca2e2598e23f6f5 197 PANTHER PTHR11002 24 197 1.9E-26 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS37175 b773a1b38f97e803bca2e2598e23f6f5 197 Gene3D G3DSA:3.40.1050.10 24 195 5.1E-36 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS37175 b773a1b38f97e803bca2e2598e23f6f5 197 SMART SM00947 22 188 2.1E-33 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS37175 b773a1b38f97e803bca2e2598e23f6f5 197 SUPERFAMILY SSF53056 21 195 3.92E-35 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS23065 6e0a8fe31065af43d2abe9ca2972ddf0 295 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 30 284 1.8E-124 T 23-04-2016 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase DC74_RS23065 6e0a8fe31065af43d2abe9ca2972ddf0 295 Pfam PF05175 Methyltransferase small domain 120 196 1.4E-9 T 23-04-2016 IPR007848 Methyltransferase small domain GO:0008168 DC74_RS23065 6e0a8fe31065af43d2abe9ca2972ddf0 295 PANTHER PTHR18895 58 266 3.0E-54 T 23-04-2016 DC74_RS23065 6e0a8fe31065af43d2abe9ca2972ddf0 295 SUPERFAMILY SSF53335 66 252 4.8E-40 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS23065 6e0a8fe31065af43d2abe9ca2972ddf0 295 PANTHER PTHR18895:SF64 58 266 3.0E-54 T 23-04-2016 DC74_RS23065 6e0a8fe31065af43d2abe9ca2972ddf0 295 Gene3D G3DSA:1.10.8.10 56 88 1.8E-5 T 23-04-2016 DC74_RS23065 6e0a8fe31065af43d2abe9ca2972ddf0 295 Gene3D G3DSA:3.40.50.150 89 272 5.7E-46 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS23065 6e0a8fe31065af43d2abe9ca2972ddf0 295 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 58 274 2.5E-42 T 23-04-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 DC74_RS11155 da58749736da27650bda5df002aef2c2 345 Gene3D G3DSA:3.40.50.1000 202 274 7.5E-32 T 23-04-2016 IPR023214 HAD-like domain DC74_RS11155 da58749736da27650bda5df002aef2c2 345 Gene3D G3DSA:3.40.50.1000 22 96 7.5E-32 T 23-04-2016 IPR023214 HAD-like domain DC74_RS11155 da58749736da27650bda5df002aef2c2 345 SUPERFAMILY SSF56784 24 274 2.34E-53 T 23-04-2016 IPR023214 HAD-like domain DC74_RS11155 da58749736da27650bda5df002aef2c2 345 Gene3D G3DSA:3.40.50.10410 97 201 1.2E-28 T 23-04-2016 IPR023215 Nitrophenylphosphatase-like domain DC74_RS11155 da58749736da27650bda5df002aef2c2 345 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 28 250 2.2E-31 T 23-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA DC74_RS11155 da58749736da27650bda5df002aef2c2 345 PANTHER PTHR19288:SF3 18 287 1.5E-83 T 23-04-2016 DC74_RS11155 da58749736da27650bda5df002aef2c2 345 Pfam PF13344 Haloacid dehalogenase-like hydrolase 28 127 2.7E-22 T 23-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA DC74_RS11155 da58749736da27650bda5df002aef2c2 345 Pfam PF13242 HAD-hyrolase-like 203 273 1.5E-16 T 23-04-2016 DC74_RS11155 da58749736da27650bda5df002aef2c2 345 PANTHER PTHR19288 18 287 1.5E-83 T 23-04-2016 DC74_RS29140 d8493be0ccb52e53079709bde099ff0e 217 Gene3D G3DSA:1.10.10.10 125 217 5.5E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29140 d8493be0ccb52e53079709bde099ff0e 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 1.2E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS29140 d8493be0ccb52e53079709bde099ff0e 217 Pfam PF00072 Response regulator receiver domain 3 113 3.1E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS29140 d8493be0ccb52e53079709bde099ff0e 217 Gene3D G3DSA:3.40.50.2300 2 119 7.3E-32 T 23-04-2016 DC74_RS29140 d8493be0ccb52e53079709bde099ff0e 217 SMART SM00448 1 112 2.6E-32 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS29140 d8493be0ccb52e53079709bde099ff0e 217 SUPERFAMILY SSF52172 2 173 6.59E-34 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS29140 d8493be0ccb52e53079709bde099ff0e 217 SMART SM00862 145 217 5.4E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS29140 d8493be0ccb52e53079709bde099ff0e 217 PANTHER PTHR26402:SF553 1 217 4.3E-108 T 23-04-2016 DC74_RS29140 d8493be0ccb52e53079709bde099ff0e 217 PANTHER PTHR26402 1 217 4.3E-108 T 23-04-2016 DC74_RS01365 7104be5fc4ebc3dd50c8787da30de2cd 281 Gene3D G3DSA:1.10.260.40 6 82 3.9E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS01365 7104be5fc4ebc3dd50c8787da30de2cd 281 PANTHER PTHR35010:SF2 6 278 2.4E-86 T 23-04-2016 DC74_RS01365 7104be5fc4ebc3dd50c8787da30de2cd 281 SMART SM00530 10 83 2.3E-9 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS01365 7104be5fc4ebc3dd50c8787da30de2cd 281 SUPERFAMILY SSF47413 30 82 1.51E-8 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS01365 7104be5fc4ebc3dd50c8787da30de2cd 281 PANTHER PTHR35010 6 278 2.4E-86 T 23-04-2016 DC74_RS01365 7104be5fc4ebc3dd50c8787da30de2cd 281 Pfam PF13560 Helix-turn-helix domain 6 86 1.1E-17 T 23-04-2016 DC74_RS19980 22e6c57bd073fa96c0c11e2ab6f15a1e 191 SUPERFAMILY SSF51283 2 184 6.02E-56 T 23-04-2016 IPR029054 dUTPase-like DC74_RS19980 22e6c57bd073fa96c0c11e2ab6f15a1e 191 PANTHER PTHR11241 2 184 2.8E-66 T 23-04-2016 DC74_RS19980 22e6c57bd073fa96c0c11e2ab6f15a1e 191 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 182 34.467 T 23-04-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187|UniPathway: UPA00610 DC74_RS19980 22e6c57bd073fa96c0c11e2ab6f15a1e 191 Pfam PF00692 dUTPase 70 178 7.0E-10 T 23-04-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 DC74_RS19980 22e6c57bd073fa96c0c11e2ab6f15a1e 191 PANTHER PTHR11241:SF7 2 184 2.8E-66 T 23-04-2016 DC74_RS19980 22e6c57bd073fa96c0c11e2ab6f15a1e 191 Gene3D G3DSA:2.70.40.10 2 184 3.0E-67 T 23-04-2016 IPR029054 dUTPase-like DC74_RS19980 22e6c57bd073fa96c0c11e2ab6f15a1e 191 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 5.8E-64 T 23-04-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187|UniPathway: UPA00610 DC74_RS35240 f94113291bf20fd9d1022ccc98a0be7e 1043 Gene3D G3DSA:3.40.50.300 897 1035 7.5E-34 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35240 f94113291bf20fd9d1022ccc98a0be7e 1043 Gene3D G3DSA:3.40.50.300 1 186 7.5E-34 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35240 f94113291bf20fd9d1022ccc98a0be7e 1043 Gene3D G3DSA:3.40.50.300 624 625 7.5E-34 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35240 f94113291bf20fd9d1022ccc98a0be7e 1043 PANTHER PTHR32114:SF2 2 1042 2.5E-103 T 23-04-2016 DC74_RS35240 f94113291bf20fd9d1022ccc98a0be7e 1043 Pfam PF13476 AAA domain 5 188 9.1E-21 T 23-04-2016 DC74_RS35240 f94113291bf20fd9d1022ccc98a0be7e 1043 Pfam PF13558 Putative exonuclease SbcCD, C subunit 933 998 3.3E-13 T 23-04-2016 DC74_RS35240 f94113291bf20fd9d1022ccc98a0be7e 1043 SUPERFAMILY SSF52540 647 699 7.3E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35240 f94113291bf20fd9d1022ccc98a0be7e 1043 SUPERFAMILY SSF52540 886 1030 7.3E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35240 f94113291bf20fd9d1022ccc98a0be7e 1043 SUPERFAMILY SSF52540 1 193 7.3E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35240 f94113291bf20fd9d1022ccc98a0be7e 1043 PANTHER PTHR32114 2 1042 2.5E-103 T 23-04-2016 IPR027050 Nuclease SbcCD subunit C GO:0004518|GO:0006281 DC74_RS19700 92cf457a250c2813723f2f352d6f68b7 477 PANTHER PTHR10342 52 471 9.0E-126 T 23-04-2016 DC74_RS19700 92cf457a250c2813723f2f352d6f68b7 477 PANTHER PTHR10342:SF199 14 36 9.0E-126 T 23-04-2016 DC74_RS19700 92cf457a250c2813723f2f352d6f68b7 477 Pfam PF00884 Sulfatase 54 381 3.6E-68 T 23-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 DC74_RS19700 92cf457a250c2813723f2f352d6f68b7 477 ProSitePatterns PS00149 Sulfatases signature 2. 148 158 - T 23-04-2016 IPR024607 Sulfatase, conserved site DC74_RS19700 92cf457a250c2813723f2f352d6f68b7 477 Gene3D G3DSA:3.30.1120.10 417 471 3.2E-16 T 23-04-2016 DC74_RS19700 92cf457a250c2813723f2f352d6f68b7 477 PANTHER PTHR10342:SF199 52 471 9.0E-126 T 23-04-2016 DC74_RS19700 92cf457a250c2813723f2f352d6f68b7 477 PANTHER PTHR10342 14 36 9.0E-126 T 23-04-2016 DC74_RS19700 92cf457a250c2813723f2f352d6f68b7 477 SUPERFAMILY SSF53649 53 466 2.33E-114 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS19700 92cf457a250c2813723f2f352d6f68b7 477 Gene3D G3DSA:3.40.720.10 52 416 1.3E-100 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 DC74_RS31940 ea9157bdae211312fe778ffa3f028468 347 PANTHER PTHR15032:SF4 54 347 5.1E-98 T 23-04-2016 DC74_RS31940 ea9157bdae211312fe778ffa3f028468 347 Pfam PF12706 Beta-lactamase superfamily domain 108 302 1.0E-45 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS31940 ea9157bdae211312fe778ffa3f028468 347 PANTHER PTHR15032 54 347 5.1E-98 T 23-04-2016 DC74_RS31940 ea9157bdae211312fe778ffa3f028468 347 SUPERFAMILY SSF56281 85 319 1.83E-38 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS31940 ea9157bdae211312fe778ffa3f028468 347 Gene3D G3DSA:3.60.15.10 72 324 2.6E-77 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS22225 a913159a05bbfcc1f7cdc11e8ab90158 307 PANTHER PTHR23344:SF20 64 306 2.1E-63 T 23-04-2016 DC74_RS22225 a913159a05bbfcc1f7cdc11e8ab90158 307 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 69 306 1.3E-30 T 23-04-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 DC74_RS22225 a913159a05bbfcc1f7cdc11e8ab90158 307 Gene3D G3DSA:3.20.20.190 60 306 9.3E-62 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS22225 a913159a05bbfcc1f7cdc11e8ab90158 307 PANTHER PTHR23344 64 306 2.1E-63 T 23-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 DC74_RS22225 a913159a05bbfcc1f7cdc11e8ab90158 307 SUPERFAMILY SSF51695 63 306 1.96E-58 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS08605 0b9b5532c3814fd8fe456eecea1ea24a 395 Gene3D G3DSA:3.50.50.60 8 94 1.3E-63 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08605 0b9b5532c3814fd8fe456eecea1ea24a 395 Gene3D G3DSA:3.50.50.60 153 231 1.3E-63 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08605 0b9b5532c3814fd8fe456eecea1ea24a 395 Gene3D G3DSA:3.50.50.60 325 385 1.3E-63 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08605 0b9b5532c3814fd8fe456eecea1ea24a 395 Pfam PF01266 FAD dependent oxidoreductase 18 363 1.3E-63 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DC74_RS08605 0b9b5532c3814fd8fe456eecea1ea24a 395 SUPERFAMILY SSF51905 17 232 2.91E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08605 0b9b5532c3814fd8fe456eecea1ea24a 395 SUPERFAMILY SSF51905 325 389 2.91E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08605 0b9b5532c3814fd8fe456eecea1ea24a 395 PANTHER PTHR13847 4 395 1.9E-75 T 23-04-2016 DC74_RS08605 0b9b5532c3814fd8fe456eecea1ea24a 395 Gene3D G3DSA:3.30.9.10 232 324 5.2E-22 T 23-04-2016 DC74_RS08605 0b9b5532c3814fd8fe456eecea1ea24a 395 Gene3D G3DSA:3.30.9.10 99 152 5.2E-22 T 23-04-2016 DC74_RS19025 b7fa009e9e15931689dec6af5e382095 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 2.5E-24 T 23-04-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 DC74_RS19025 b7fa009e9e15931689dec6af5e382095 99 PANTHER PTHR11434:SF0 2 98 7.5E-37 T 23-04-2016 DC74_RS19025 b7fa009e9e15931689dec6af5e382095 99 PANTHER PTHR11434 2 98 7.5E-37 T 23-04-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 DC74_RS19025 b7fa009e9e15931689dec6af5e382095 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 19.774 T 23-04-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 DC74_RS14885 bae1562f125019b65896bc04aa2f008e 248 Hamap MF_00201 DNA repair protein RecO [recO]. 2 248 25.873 T 23-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 DC74_RS14885 bae1562f125019b65896bc04aa2f008e 248 Pfam PF02565 Recombination protein O C terminal 91 244 1.8E-33 T 23-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 DC74_RS14885 bae1562f125019b65896bc04aa2f008e 248 PANTHER PTHR33991 2 247 8.1E-56 T 23-04-2016 DC74_RS14885 bae1562f125019b65896bc04aa2f008e 248 Pfam PF11967 Recombination protein O N terminal 1 85 1.6E-27 T 23-04-2016 IPR022572 DNA replication/recombination mediator RecO, N-terminal DC74_RS14885 bae1562f125019b65896bc04aa2f008e 248 SUPERFAMILY SSF50249 1 83 4.11E-18 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS14885 bae1562f125019b65896bc04aa2f008e 248 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 207 1.9E-35 T 23-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 DC74_RS14885 bae1562f125019b65896bc04aa2f008e 248 SUPERFAMILY SSF57863 89 238 1.88E-39 T 23-04-2016 DC74_RS14885 bae1562f125019b65896bc04aa2f008e 248 Gene3D G3DSA:2.40.50.140 1 87 4.9E-35 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS39405 0998d34adacbc63aa3bc3323a778f0e8 247 SUPERFAMILY SSF53335 26 220 2.26E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS39405 0998d34adacbc63aa3bc3323a778f0e8 247 PANTHER PTHR10108 6 167 2.2E-23 T 23-04-2016 DC74_RS39405 0998d34adacbc63aa3bc3323a778f0e8 247 PANTHER PTHR10108 185 230 2.2E-23 T 23-04-2016 DC74_RS39405 0998d34adacbc63aa3bc3323a778f0e8 247 Pfam PF13649 Methyltransferase domain 42 138 2.8E-20 T 23-04-2016 DC74_RS39405 0998d34adacbc63aa3bc3323a778f0e8 247 Gene3D G3DSA:3.40.50.150 4 214 2.3E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 Pfam PF00067 Cytochrome P450 262 366 5.1E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PANTHER PTHR24286:SF42 31 148 4.1E-58 T 23-04-2016 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 SUPERFAMILY SSF48264 22 378 8.77E-50 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PRINTS PR00359 B-class P450 signature 348 359 1.2E-8 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PRINTS PR00359 B-class P450 signature 73 84 1.2E-8 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PRINTS PR00359 B-class P450 signature 339 348 1.2E-8 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PRINTS PR00359 B-class P450 signature 262 273 1.2E-8 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PRINTS PR00359 B-class P450 signature 185 207 1.2E-8 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PRINTS PR00385 P450 superfamily signature 348 359 1.8E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PRINTS PR00385 P450 superfamily signature 339 348 1.8E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PRINTS PR00385 P450 superfamily signature 226 243 1.8E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PRINTS PR00385 P450 superfamily signature 262 273 1.8E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 Gene3D G3DSA:1.10.630.10 14 397 7.3E-59 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PANTHER PTHR24286 166 376 4.1E-58 T 23-04-2016 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PANTHER PTHR24286:SF42 166 376 4.1E-58 T 23-04-2016 DC74_RS34110 61c62384acd9b7b1247df40c3235c502 401 PANTHER PTHR24286 31 148 4.1E-58 T 23-04-2016 DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 16 179 0.0065 T 23-04-2016 DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 7.4E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 7.4E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 7.4E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 Gene3D G3DSA:3.40.50.720 12 253 4.1E-82 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PANTHER PTHR24322 20 145 4.1E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PANTHER PTHR24322 161 197 4.1E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 252 9.7E-67 T 23-04-2016 DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 SUPERFAMILY SSF51735 15 253 2.37E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 5.7E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 5.7E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 5.7E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 5.7E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 5.7E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 5.7E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PANTHER PTHR24322:SF242 20 145 4.1E-50 T 23-04-2016 DC74_RS10575 08782004ecc65d100281b60bb0fae000 263 PANTHER PTHR24322:SF242 161 197 4.1E-50 T 23-04-2016 DC74_RS39650 52d8f6865ab84b9bd3f03283fb1531ba 182 PANTHER PTHR10156 9 140 2.1E-14 T 23-04-2016 IPR008431 Cyclic nucleotide phosphodiesterase GO:0004113|GO:0009214|GO:0016020 DC74_RS39650 52d8f6865ab84b9bd3f03283fb1531ba 182 Gene3D G3DSA:3.40.50.300 7 164 7.3E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39650 52d8f6865ab84b9bd3f03283fb1531ba 182 Pfam PF13671 AAA domain 9 135 2.2E-6 T 23-04-2016 DC74_RS39650 52d8f6865ab84b9bd3f03283fb1531ba 182 PANTHER PTHR10156:SF1 9 140 2.1E-14 T 23-04-2016 DC74_RS39650 52d8f6865ab84b9bd3f03283fb1531ba 182 SUPERFAMILY SSF52540 8 165 1.43E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS01815 2b352de2865cb54ec0c7ad52a2bc2c88 247 Pfam PF13493 Domain of unknown function (DUF4118) 12 110 2.1E-19 T 23-04-2016 IPR025201 Sensor protein KdpD, transmembrane domain DC74_RS01815 2b352de2865cb54ec0c7ad52a2bc2c88 247 Gene3D G3DSA:1.20.120.620 10 109 2.4E-20 T 23-04-2016 DC74_RS35915 01c8b108d736513384d93534ffa76f30 252 Gene3D G3DSA:3.30.20.10 116 171 1.5E-24 T 23-04-2016 DC74_RS35915 01c8b108d736513384d93534ffa76f30 252 Gene3D G3DSA:1.10.530.10 50 108 4.5E-57 T 23-04-2016 DC74_RS35915 01c8b108d736513384d93534ffa76f30 252 Gene3D G3DSA:1.10.530.10 172 252 4.5E-57 T 23-04-2016 DC74_RS35915 01c8b108d736513384d93534ffa76f30 252 Pfam PF00182 Chitinase class I 50 252 4.7E-45 T 23-04-2016 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 DC74_RS35915 01c8b108d736513384d93534ffa76f30 252 PIRSF PIRSF001060 7 252 2.4E-85 T 23-04-2016 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 DC74_RS35915 01c8b108d736513384d93534ffa76f30 252 PANTHER PTHR22595 50 252 3.8E-92 T 23-04-2016 DC74_RS35915 01c8b108d736513384d93534ffa76f30 252 SUPERFAMILY SSF53955 49 252 7.31E-70 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 Pfam PF03952 Enolase, N-terminal domain 4 134 5.4E-55 T 23-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 SUPERFAMILY SSF54826 4 137 6.7E-52 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 Gene3D G3DSA:3.20.20.120 128 424 1.5E-127 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 SMART SM01192 139 425 8.7E-205 T 23-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 PIRSF PIRSF001400 1 425 2.1E-180 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 424 6.3E-124 T 23-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 PANTHER PTHR11902 1 424 1.5E-241 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 PRINTS PR00148 Enolase signature 363 380 3.1E-44 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 PRINTS PR00148 Enolase signature 37 51 3.1E-44 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 PRINTS PR00148 Enolase signature 334 348 3.1E-44 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 PRINTS PR00148 Enolase signature 107 123 3.1E-44 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 PRINTS PR00148 Enolase signature 161 174 3.1E-44 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 PRINTS PR00148 Enolase signature 311 322 3.1E-44 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 SUPERFAMILY SSF51604 139 424 1.5E-121 T 23-04-2016 IPR029065 Enolase C-terminal domain-like DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 Hamap MF_00318 Enolase [eno]. 2 411 43.044 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 424 5.5E-197 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 SMART SM01193 4 134 9.2E-85 T 23-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 DC74_RS09160 284979f87944a9a67de7a77fe19c5d0c 428 Gene3D G3DSA:3.30.390.10 4 126 1.1E-50 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DC74_RS25315 c8f6f4ae756745994009c0b14eab82d9 447 PANTHER PTHR11895 7 442 1.4E-84 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS25315 c8f6f4ae756745994009c0b14eab82d9 447 Gene3D G3DSA:3.90.1300.10 12 436 1.8E-100 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS25315 c8f6f4ae756745994009c0b14eab82d9 447 Pfam PF01425 Amidase 26 425 8.7E-72 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS25315 c8f6f4ae756745994009c0b14eab82d9 447 SUPERFAMILY SSF75304 8 436 1.05E-97 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS38035 db3bf77fca3c7336ac2fa46426028b33 430 Pfam PF13416 Bacterial extracellular solute-binding protein 60 355 3.2E-34 T 23-04-2016 DC74_RS38035 db3bf77fca3c7336ac2fa46426028b33 430 Gene3D G3DSA:3.40.190.10 43 159 1.5E-5 T 23-04-2016 DC74_RS38035 db3bf77fca3c7336ac2fa46426028b33 430 PANTHER PTHR30061 1 430 3.9E-54 T 23-04-2016 DC74_RS38035 db3bf77fca3c7336ac2fa46426028b33 430 Gene3D G3DSA:3.40.190.10 160 360 2.5E-32 T 23-04-2016 DC74_RS38035 db3bf77fca3c7336ac2fa46426028b33 430 SUPERFAMILY SSF53850 38 424 5.27E-62 T 23-04-2016 DC74_RS03990 c989431a313217ecc8168d0b2ea9fcff 303 Pfam PF00561 alpha/beta hydrolase fold 37 285 7.2E-27 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS03990 c989431a313217ecc8168d0b2ea9fcff 303 SUPERFAMILY SSF53474 8 299 2.72E-50 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS03990 c989431a313217ecc8168d0b2ea9fcff 303 PRINTS PR00111 Alpha/beta hydrolase fold signature 137 150 1.0E-7 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS03990 c989431a313217ecc8168d0b2ea9fcff 303 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 1.0E-7 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS03990 c989431a313217ecc8168d0b2ea9fcff 303 PRINTS PR00111 Alpha/beta hydrolase fold signature 247 261 1.0E-7 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS03990 c989431a313217ecc8168d0b2ea9fcff 303 PANTHER PTHR10992 97 303 8.4E-40 T 23-04-2016 DC74_RS03990 c989431a313217ecc8168d0b2ea9fcff 303 PANTHER PTHR10992 6 81 8.4E-40 T 23-04-2016 DC74_RS03990 c989431a313217ecc8168d0b2ea9fcff 303 Gene3D G3DSA:3.40.50.1820 16 299 5.5E-57 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS07065 6f9260b79ce18ab5103fc761b9345bc7 170 SUPERFAMILY SSF47741 88 160 2.22E-28 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS07065 6f9260b79ce18ab5103fc761b9345bc7 170 Pfam PF01799 [2Fe-2S] binding domain 71 149 3.5E-26 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS07065 6f9260b79ce18ab5103fc761b9345bc7 170 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS07065 6f9260b79ce18ab5103fc761b9345bc7 170 Gene3D G3DSA:3.10.20.30 2 72 3.4E-28 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS07065 6f9260b79ce18ab5103fc761b9345bc7 170 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 4 57 9.3E-8 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS07065 6f9260b79ce18ab5103fc761b9345bc7 170 Gene3D G3DSA:1.10.150.120 73 164 4.4E-30 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS07065 6f9260b79ce18ab5103fc761b9345bc7 170 PANTHER PTHR11908 1 148 6.7E-41 T 23-04-2016 DC74_RS07065 6f9260b79ce18ab5103fc761b9345bc7 170 SUPERFAMILY SSF54292 4 76 6.69E-24 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS07960 b3971cfa1e782a62f2612b56855dfd4c 501 Gene3D G3DSA:3.30.300.30 391 492 4.7E-32 T 23-04-2016 DC74_RS07960 b3971cfa1e782a62f2612b56855dfd4c 501 PANTHER PTHR24096:SF206 20 490 2.6E-190 T 23-04-2016 DC74_RS07960 b3971cfa1e782a62f2612b56855dfd4c 501 Pfam PF00501 AMP-binding enzyme 15 394 8.3E-80 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS07960 b3971cfa1e782a62f2612b56855dfd4c 501 PANTHER PTHR24096 20 490 2.6E-190 T 23-04-2016 DC74_RS07960 b3971cfa1e782a62f2612b56855dfd4c 501 SUPERFAMILY SSF56801 12 493 1.14E-124 T 23-04-2016 DC74_RS07960 b3971cfa1e782a62f2612b56855dfd4c 501 ProSitePatterns PS00455 Putative AMP-binding domain signature. 145 156 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS07960 b3971cfa1e782a62f2612b56855dfd4c 501 Pfam PF13193 AMP-binding enzyme C-terminal domain 404 483 9.6E-23 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS07960 b3971cfa1e782a62f2612b56855dfd4c 501 Gene3D G3DSA:2.30.38.10 312 388 8.5E-28 T 23-04-2016 DC74_RS07960 b3971cfa1e782a62f2612b56855dfd4c 501 Gene3D G3DSA:3.40.50.980 15 150 2.0E-23 T 23-04-2016 DC74_RS07960 b3971cfa1e782a62f2612b56855dfd4c 501 Gene3D G3DSA:3.40.50.980 151 311 2.3E-33 T 23-04-2016 DC74_RS11350 a45fcc36e0148a32cfa0c0cd93ecc073 329 SUPERFAMILY SSF102114 2 277 3.79E-72 T 23-04-2016 DC74_RS11350 a45fcc36e0148a32cfa0c0cd93ecc073 329 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 2 329 2.2E-110 T 23-04-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS11350 a45fcc36e0148a32cfa0c0cd93ecc073 329 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 23-04-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS11350 a45fcc36e0148a32cfa0c0cd93ecc073 329 PANTHER PTHR22960 1 285 2.3E-124 T 23-04-2016 DC74_RS11350 a45fcc36e0148a32cfa0c0cd93ecc073 329 Pfam PF06463 Molybdenum Cofactor Synthesis C 183 309 9.1E-36 T 23-04-2016 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS11350 a45fcc36e0148a32cfa0c0cd93ecc073 329 Pfam PF13353 4Fe-4S single cluster domain 18 104 8.1E-7 T 23-04-2016 DC74_RS11350 a45fcc36e0148a32cfa0c0cd93ecc073 329 Gene3D G3DSA:3.20.20.70 2 305 5.5E-78 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS11350 a45fcc36e0148a32cfa0c0cd93ecc073 329 Pfam PF04055 Radical SAM superfamily 16 177 5.3E-33 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS11350 a45fcc36e0148a32cfa0c0cd93ecc073 329 SMART SM00729 11 213 1.7E-10 T 23-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 DC74_RS11350 a45fcc36e0148a32cfa0c0cd93ecc073 329 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 2 329 40.925 T 23-04-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 PIRSF PIRSF038928 2 487 2.0E-235 T 23-04-2016 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 Pfam PF06628 Catalase-related immune-responsive 422 484 3.5E-17 T 23-04-2016 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 ProSitePatterns PS00438 Catalase proximal active site signature. 48 64 - T 23-04-2016 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 SMART SM01060 12 394 1.9E-280 T 23-04-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 337 345 - T 23-04-2016 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 PANTHER PTHR11465 1 485 1.0E-279 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 PRINTS PR00067 Catalase signature 25 48 5.2E-68 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 PRINTS PR00067 Catalase signature 324 350 5.2E-68 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 PRINTS PR00067 Catalase signature 87 105 5.2E-68 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 PRINTS PR00067 Catalase signature 292 319 5.2E-68 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 PRINTS PR00067 Catalase signature 127 145 5.2E-68 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 PRINTS PR00067 Catalase signature 108 125 5.2E-68 T 23-04-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 SUPERFAMILY SSF56634 6 485 9.29E-204 T 23-04-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 Gene3D G3DSA:2.40.180.10 4 361 3.7E-178 T 23-04-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS25555 5ed4c3efdf4519b45053a41270853f8b 487 Pfam PF00199 Catalase 12 390 1.5E-187 T 23-04-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 DC74_RS27325 417f55095048013828a6f711c8aa7840 575 Gene3D G3DSA:3.90.400.10 123 190 2.1E-24 T 23-04-2016 DC74_RS27325 417f55095048013828a6f711c8aa7840 575 SMART SM00642 31 433 1.1E-121 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS27325 417f55095048013828a6f711c8aa7840 575 PANTHER PTHR10357 457 570 5.4E-294 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS27325 417f55095048013828a6f711c8aa7840 575 PANTHER PTHR10357:SF164 457 570 5.4E-294 T 23-04-2016 DC74_RS27325 417f55095048013828a6f711c8aa7840 575 PANTHER PTHR10357:SF164 2 418 5.4E-294 T 23-04-2016 DC74_RS27325 417f55095048013828a6f711c8aa7840 575 Pfam PF16657 Maltogenic Amylase, C-terminal domain 481 564 1.4E-23 T 23-04-2016 IPR032091 Maltogenic Amylase, C-terminal DC74_RS27325 417f55095048013828a6f711c8aa7840 575 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 23 567 5.4E-300 T 23-04-2016 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 DC74_RS27325 417f55095048013828a6f711c8aa7840 575 Gene3D G3DSA:2.60.40.1180 486 566 6.1E-11 T 23-04-2016 IPR013780 Glycosyl hydrolase, all-beta DC74_RS27325 417f55095048013828a6f711c8aa7840 575 SUPERFAMILY SSF51445 34 481 1.72E-136 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS27325 417f55095048013828a6f711c8aa7840 575 PANTHER PTHR10357 2 418 5.4E-294 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS27325 417f55095048013828a6f711c8aa7840 575 Pfam PF00128 Alpha amylase, catalytic domain 46 402 3.0E-79 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS27325 417f55095048013828a6f711c8aa7840 575 Gene3D G3DSA:3.20.20.80 25 122 2.1E-112 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS27325 417f55095048013828a6f711c8aa7840 575 Gene3D G3DSA:3.20.20.80 460 474 2.1E-112 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS27325 417f55095048013828a6f711c8aa7840 575 Gene3D G3DSA:3.20.20.80 198 427 2.1E-112 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS27325 417f55095048013828a6f711c8aa7840 575 SUPERFAMILY SSF51011 486 567 5.31E-16 T 23-04-2016 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 35.546 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 2.3E-34 T 23-04-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 282 1.3E-58 T 23-04-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 Gene3D G3DSA:3.40.192.10 7 139 1.1E-41 T 23-04-2016 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 Gene3D G3DSA:3.40.50.720 140 264 2.4E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.1E-59 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 1.1E-59 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 1.1E-59 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.1E-59 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.1E-59 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.1E-59 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 PANTHER PTHR10025 1 288 6.0E-130 T 23-04-2016 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 SUPERFAMILY SSF53223 1 121 2.59E-36 T 23-04-2016 DC74_RS24570 44105453b8ead1e7a1ccb01bfd9ce656 289 SUPERFAMILY SSF51735 122 281 4.41E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 PANTHER PTHR10992:SF305 4 162 2.5E-109 T 23-04-2016 DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 PANTHER PTHR10992:SF305 206 319 2.5E-109 T 23-04-2016 DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 Pfam PF00561 alpha/beta hydrolase fold 23 305 1.2E-23 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 Gene3D G3DSA:3.40.50.1820 2 178 4.5E-88 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 Gene3D G3DSA:3.40.50.1820 210 320 4.5E-88 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 SUPERFAMILY SSF53474 210 319 3.3E-72 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 SUPERFAMILY SSF53474 2 180 3.3E-72 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 PRINTS PR00412 Epoxide hydrolase signature 29 47 1.0E-32 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 PRINTS PR00412 Epoxide hydrolase signature 109 122 1.0E-32 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 PRINTS PR00412 Epoxide hydrolase signature 49 64 1.0E-32 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 PRINTS PR00412 Epoxide hydrolase signature 294 316 1.0E-32 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 PRINTS PR00412 Epoxide hydrolase signature 255 271 1.0E-32 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 PRINTS PR00412 Epoxide hydrolase signature 95 108 1.0E-32 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 PANTHER PTHR10992 4 162 2.5E-109 T 23-04-2016 DC74_RS34615 35b1da92a163965ebd0a9ad553fbce2c 322 PANTHER PTHR10992 206 319 2.5E-109 T 23-04-2016 DC74_RS03555 bc1a601d7817b2e054734f173cf9d1e3 141 SUPERFAMILY SSF46785 19 125 1.88E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03555 bc1a601d7817b2e054734f173cf9d1e3 141 PANTHER PTHR34134 1 136 2.5E-31 T 23-04-2016 DC74_RS03555 bc1a601d7817b2e054734f173cf9d1e3 141 PANTHER PTHR34134:SF1 1 136 2.5E-31 T 23-04-2016 DC74_RS03555 bc1a601d7817b2e054734f173cf9d1e3 141 Gene3D G3DSA:1.10.10.10 18 89 7.5E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03555 bc1a601d7817b2e054734f173cf9d1e3 141 Pfam PF03965 Penicillinase repressor 18 125 2.3E-24 T 23-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 DC74_RS33695 1e8144a215c3bfbdcd33e3931fbcee43 350 Pfam PF00089 Trypsin 151 324 7.0E-6 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS33695 1e8144a215c3bfbdcd33e3931fbcee43 350 SUPERFAMILY SSF50494 125 332 5.1E-19 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS33695 1e8144a215c3bfbdcd33e3931fbcee43 350 Gene3D G3DSA:2.40.10.10 156 238 1.6E-12 T 23-04-2016 DC74_RS06240 2c7e930352ff79755e6676ab58861ad5 250 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 7 229 8.9E-66 T 23-04-2016 IPR012666 Cobalt transporter subunit CbtA, putative DC74_RS31640 ad506eb7d37568ee7f991708a04f836a 247 Pfam PF14099 Polysaccharide lyase 39 230 2.2E-14 T 23-04-2016 IPR025975 Polysaccharide lyase MetaCyc: PWY-7644 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 PRINTS PR00171 Sugar transporter signature 379 391 1.2E-18 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 PRINTS PR00171 Sugar transporter signature 114 133 1.2E-18 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 PRINTS PR00171 Sugar transporter signature 31 41 1.2E-18 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 PRINTS PR00171 Sugar transporter signature 266 276 1.2E-18 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 PRINTS PR00171 Sugar transporter signature 356 377 1.2E-18 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 Pfam PF00083 Sugar (and other) transporter 24 455 2.2E-95 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 PANTHER PTHR23500 22 461 2.2E-128 T 23-04-2016 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 Gene3D G3DSA:1.20.1250.20 256 450 1.2E-21 T 23-04-2016 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 Gene3D G3DSA:1.20.1250.20 28 204 7.0E-27 T 23-04-2016 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 94 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 ProSitePatterns PS00216 Sugar transport proteins signature 1. 311 327 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 ProSitePatterns PS00217 Sugar transport proteins signature 2. 119 144 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 25 451 4.7E-90 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS32975 fc698311ef6553f51018c1e3c44a09ce 485 SUPERFAMILY SSF103473 9 453 1.22E-73 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS11115 932d276a1180950fc9e69a1cf365a914 271 Gene3D G3DSA:3.40.50.150 99 160 2.4E-6 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS11115 932d276a1180950fc9e69a1cf365a914 271 PIRSF PIRSF005578 3 268 8.6E-94 T 23-04-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 DC74_RS11115 932d276a1180950fc9e69a1cf365a914 271 Pfam PF01479 S4 domain 7 51 8.4E-11 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS11115 932d276a1180950fc9e69a1cf365a914 271 Gene3D G3DSA:3.10.290.10 7 98 4.5E-25 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS11115 932d276a1180950fc9e69a1cf365a914 271 PANTHER PTHR32319:SF0 1 271 1.4E-113 T 23-04-2016 DC74_RS11115 932d276a1180950fc9e69a1cf365a914 271 Pfam PF01728 FtsJ-like methyltransferase 65 250 1.6E-18 T 23-04-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 DC74_RS11115 932d276a1180950fc9e69a1cf365a914 271 SUPERFAMILY SSF55174 6 60 1.77E-12 T 23-04-2016 DC74_RS11115 932d276a1180950fc9e69a1cf365a914 271 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 8 245 3.3E-59 T 23-04-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 DC74_RS11115 932d276a1180950fc9e69a1cf365a914 271 SUPERFAMILY SSF53335 64 251 5.15E-21 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS11115 932d276a1180950fc9e69a1cf365a914 271 SMART SM00363 7 74 3.8E-8 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS11115 932d276a1180950fc9e69a1cf365a914 271 PANTHER PTHR32319 1 271 1.4E-113 T 23-04-2016 DC74_RS27785 6de15e8607c70c2f14bfc7e6cbcf1979 205 SUPERFAMILY SSF101874 32 204 4.19E-56 T 23-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like DC74_RS27785 6de15e8607c70c2f14bfc7e6cbcf1979 205 SMART SM00867 33 202 6.4E-68 T 23-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like DC74_RS27785 6de15e8607c70c2f14bfc7e6cbcf1979 205 PANTHER PTHR34406 7 205 3.5E-62 T 23-04-2016 DC74_RS27785 6de15e8607c70c2f14bfc7e6cbcf1979 205 Pfam PF04264 YceI-like domain 34 200 7.5E-45 T 23-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like DC74_RS27785 6de15e8607c70c2f14bfc7e6cbcf1979 205 PANTHER PTHR34406:SF1 7 205 3.5E-62 T 23-04-2016 DC74_RS27785 6de15e8607c70c2f14bfc7e6cbcf1979 205 Gene3D G3DSA:2.40.128.110 32 204 4.7E-61 T 23-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like DC74_RS14110 3910ac5f019713b2c2ffe0c62f732491 142 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 9 141 8.6E-54 T 23-04-2016 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 DC74_RS14110 3910ac5f019713b2c2ffe0c62f732491 142 Gene3D G3DSA:2.20.25.10 5 49 1.5E-18 T 23-04-2016 DC74_RS14110 3910ac5f019713b2c2ffe0c62f732491 142 Gene3D G3DSA:3.30.300.20 50 141 3.5E-35 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta DC74_RS14110 3910ac5f019713b2c2ffe0c62f732491 142 PANTHER PTHR33797:SF2 3 141 5.3E-65 T 23-04-2016 DC74_RS14110 3910ac5f019713b2c2ffe0c62f732491 142 SUPERFAMILY SSF82784 4 141 3.93E-41 T 23-04-2016 IPR003718 OsmC/Ohr family DC74_RS14110 3910ac5f019713b2c2ffe0c62f732491 142 PANTHER PTHR33797 3 141 5.3E-65 T 23-04-2016 DC74_RS14110 3910ac5f019713b2c2ffe0c62f732491 142 Pfam PF02566 OsmC-like protein 43 139 1.2E-16 T 23-04-2016 IPR003718 OsmC/Ohr family DC74_RS34645 3a3c53b110cda43ee19bbe649c374d14 167 Gene3D G3DSA:1.10.1740.10 3 98 2.9E-21 T 23-04-2016 DC74_RS34645 3a3c53b110cda43ee19bbe649c374d14 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 159 6.0E-26 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS34645 3a3c53b110cda43ee19bbe649c374d14 167 PANTHER PTHR30173 1 167 1.9E-51 T 23-04-2016 DC74_RS34645 3a3c53b110cda43ee19bbe649c374d14 167 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 28 60 - T 23-04-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS34645 3a3c53b110cda43ee19bbe649c374d14 167 PANTHER PTHR30173:SF17 1 167 1.9E-51 T 23-04-2016 DC74_RS34645 3a3c53b110cda43ee19bbe649c374d14 167 SUPERFAMILY SSF88659 95 161 1.64E-14 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS34645 3a3c53b110cda43ee19bbe649c374d14 167 Gene3D G3DSA:1.10.10.10 99 162 6.0E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34645 3a3c53b110cda43ee19bbe649c374d14 167 Pfam PF04542 Sigma-70 region 2 5 73 2.0E-18 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS34645 3a3c53b110cda43ee19bbe649c374d14 167 Pfam PF04545 Sigma-70, region 4 111 157 4.5E-14 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS34645 3a3c53b110cda43ee19bbe649c374d14 167 SUPERFAMILY SSF88946 3 85 4.32E-19 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS33540 72ac147380a7f55b8f4a8b4c507996bc 363 PANTHER PTHR30344:SF1 21 361 5.5E-103 T 23-04-2016 DC74_RS33540 72ac147380a7f55b8f4a8b4c507996bc 363 SUPERFAMILY SSF51004 31 362 3.92E-49 T 23-04-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain DC74_RS33540 72ac147380a7f55b8f4a8b4c507996bc 363 PANTHER PTHR30344 21 361 5.5E-103 T 23-04-2016 DC74_RS33540 72ac147380a7f55b8f4a8b4c507996bc 363 Pfam PF10282 Lactonase, 7-bladed beta-propeller 21 360 1.1E-100 T 23-04-2016 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31|UniPathway: UPA00115 DC74_RS33540 72ac147380a7f55b8f4a8b4c507996bc 363 Gene3D G3DSA:2.130.10.10 19 360 1.5E-95 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS33330 166a11b09cf89e908485154d71d2050b 502 SMART SM00387 290 403 8.4E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33330 166a11b09cf89e908485154d71d2050b 502 PANTHER PTHR24423:SF523 439 492 3.9E-48 T 23-04-2016 DC74_RS33330 166a11b09cf89e908485154d71d2050b 502 PANTHER PTHR24423:SF523 154 406 3.9E-48 T 23-04-2016 DC74_RS33330 166a11b09cf89e908485154d71d2050b 502 PANTHER PTHR24423 439 492 3.9E-48 T 23-04-2016 DC74_RS33330 166a11b09cf89e908485154d71d2050b 502 PANTHER PTHR24423 154 406 3.9E-48 T 23-04-2016 DC74_RS33330 166a11b09cf89e908485154d71d2050b 502 Gene3D G3DSA:3.30.565.10 261 402 3.7E-15 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33330 166a11b09cf89e908485154d71d2050b 502 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 295 400 1.5E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33330 166a11b09cf89e908485154d71d2050b 502 SUPERFAMILY SSF55874 291 405 1.13E-16 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS07495 146122c6d5df3767ec854127fb138a36 422 PANTHER PTHR11712 3 417 2.6E-138 T 23-04-2016 DC74_RS07495 146122c6d5df3767ec854127fb138a36 422 SUPERFAMILY SSF53901 219 417 4.22E-67 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS07495 146122c6d5df3767ec854127fb138a36 422 SMART SM00825 Beta-ketoacyl synthase 5 408 6.4E-14 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS07495 146122c6d5df3767ec854127fb138a36 422 Gene3D G3DSA:3.40.47.10 271 416 6.1E-54 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS07495 146122c6d5df3767ec854127fb138a36 422 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 374 3.0E-33 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS07495 146122c6d5df3767ec854127fb138a36 422 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 160 176 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS07495 146122c6d5df3767ec854127fb138a36 422 Gene3D G3DSA:3.40.47.10 2 263 5.6E-73 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS07495 146122c6d5df3767ec854127fb138a36 422 SUPERFAMILY SSF53901 3 257 5.01E-68 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS07495 146122c6d5df3767ec854127fb138a36 422 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 252 5.8E-54 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS18305 41993f16f65f438869f8cc124aec90bc 156 PANTHER PTHR39428 12 156 7.2E-29 T 23-04-2016 DC74_RS18305 41993f16f65f438869f8cc124aec90bc 156 SUPERFAMILY SSF50475 54 151 1.77E-7 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS18305 41993f16f65f438869f8cc124aec90bc 156 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 45 154 1.1E-27 T 23-04-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 DC74_RS18305 41993f16f65f438869f8cc124aec90bc 156 Pfam PF04075 Domain of unknown function (DUF385) 34 150 8.3E-26 T 23-04-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 DC74_RS03060 cb65ad4db332d459c77c65bef7a082dc 288 Pfam PF00892 EamA-like transporter family 131 257 1.4E-13 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS03060 cb65ad4db332d459c77c65bef7a082dc 288 SUPERFAMILY SSF103481 31 120 6.41E-6 T 23-04-2016 DC74_RS03060 cb65ad4db332d459c77c65bef7a082dc 288 PANTHER PTHR22911 1 269 1.8E-44 T 23-04-2016 DC74_RS03060 cb65ad4db332d459c77c65bef7a082dc 288 PANTHER PTHR22911:SF37 1 269 1.8E-44 T 23-04-2016 DC74_RS03060 cb65ad4db332d459c77c65bef7a082dc 288 SUPERFAMILY SSF103481 171 267 2.48E-9 T 23-04-2016 DC74_RS27430 d4be4620227726bf79c4eec2372c8ac1 139 PANTHER PTHR34134:SF1 1 131 1.4E-31 T 23-04-2016 DC74_RS27430 d4be4620227726bf79c4eec2372c8ac1 139 SUPERFAMILY SSF46785 13 122 1.93E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27430 d4be4620227726bf79c4eec2372c8ac1 139 PANTHER PTHR34134 1 131 1.4E-31 T 23-04-2016 DC74_RS27430 d4be4620227726bf79c4eec2372c8ac1 139 Pfam PF03965 Penicillinase repressor 13 121 5.2E-23 T 23-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 DC74_RS27430 d4be4620227726bf79c4eec2372c8ac1 139 Gene3D G3DSA:1.10.10.10 13 79 1.8E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35105 9e64dfc862c38d6ee2d352fa87f2e088 136 SUPERFAMILY SSF103196 4 129 1.22E-26 T 23-04-2016 DC74_RS35105 9e64dfc862c38d6ee2d352fa87f2e088 136 Gene3D G3DSA:3.30.450.30 4 127 2.0E-24 T 23-04-2016 DC74_RS35105 9e64dfc862c38d6ee2d352fa87f2e088 136 PANTHER PTHR36222 4 130 6.6E-42 T 23-04-2016 DC74_RS35105 9e64dfc862c38d6ee2d352fa87f2e088 136 SMART SM00960 6 100 1.2E-18 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS35105 9e64dfc862c38d6ee2d352fa87f2e088 136 Pfam PF03259 Roadblock/LC7 domain 7 99 1.8E-19 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS14965 c07368add483deaab03860d449a68aa2 333 SUPERFAMILY SSF52540 115 297 7.19E-40 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14965 c07368add483deaab03860d449a68aa2 333 Gene3D G3DSA:3.40.50.300 121 325 1.7E-102 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14965 c07368add483deaab03860d449a68aa2 333 Pfam PF02562 PhoH-like protein 122 325 3.4E-95 T 23-04-2016 IPR003714 PhoH-like protein GO:0005524 DC74_RS14965 c07368add483deaab03860d449a68aa2 333 PANTHER PTHR30473 22 331 1.0E-165 T 23-04-2016 DC74_RS14965 c07368add483deaab03860d449a68aa2 333 PANTHER PTHR30473:SF1 22 331 1.0E-165 T 23-04-2016 DC74_RS32005 4f0fc57f0a2b0399660db2ef5c67fee6 239 PANTHER PTHR30055 19 149 5.9E-34 T 23-04-2016 DC74_RS32005 4f0fc57f0a2b0399660db2ef5c67fee6 239 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 99 235 3.5E-15 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS32005 4f0fc57f0a2b0399660db2ef5c67fee6 239 PANTHER PTHR30055:SF93 19 149 5.9E-34 T 23-04-2016 DC74_RS32005 4f0fc57f0a2b0399660db2ef5c67fee6 239 SUPERFAMILY SSF48498 98 237 2.33E-20 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS32005 4f0fc57f0a2b0399660db2ef5c67fee6 239 SUPERFAMILY SSF46689 25 88 1.1E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS32005 4f0fc57f0a2b0399660db2ef5c67fee6 239 Gene3D G3DSA:1.10.357.10 23 238 3.8E-49 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS32005 4f0fc57f0a2b0399660db2ef5c67fee6 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 80 1.5E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS17885 5b82204df7dee06585e957bd8993baea 135 Pfam PF00501 AMP-binding enzyme 2 86 8.2E-14 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS17885 5b82204df7dee06585e957bd8993baea 135 Gene3D G3DSA:3.40.50.980 2 82 1.3E-13 T 23-04-2016 DC74_RS17885 5b82204df7dee06585e957bd8993baea 135 PANTHER PTHR24095 2 134 1.1E-19 T 23-04-2016 DC74_RS17885 5b82204df7dee06585e957bd8993baea 135 SUPERFAMILY SSF56801 2 134 2.49E-21 T 23-04-2016 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 Gene3D G3DSA:3.20.20.70 513 839 6.1E-75 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 Gene3D G3DSA:3.20.20.70 50 382 6.1E-67 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 549 862 1.4E-103 T 23-04-2016 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 Hamap MF_01611 FO synthase subunit 1 [cofG]. 90 421 49.969 T 23-04-2016 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 PANTHER PTHR22976 474 887 2.7E-285 T 23-04-2016 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 SMART SM00729 94 331 2.4E-6 T 23-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 91 419 2.8E-141 T 23-04-2016 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 SUPERFAMILY SSF102114 50 395 2.22E-36 T 23-04-2016 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 SUPERFAMILY SSF102114 512 828 5.1E-49 T 23-04-2016 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 514 864 7.4E-158 T 23-04-2016 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 Pfam PF04055 Radical SAM superfamily 557 728 1.2E-15 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 Pfam PF04055 Radical SAM superfamily 98 280 1.2E-12 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 PANTHER PTHR22976:SF22 474 887 2.7E-285 T 23-04-2016 DC74_RS18155 913180624cf5e613e2dad4411a264a0e 887 Hamap MF_01612 FO synthase subunit 2 [cofH]. 500 865 47.879 T 23-04-2016 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 DC74_RS36195 2a8f746daaa641b2f454bc2f8841655d 84 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 77 6.3E-5 T 23-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family DC74_RS36195 2a8f746daaa641b2f454bc2f8841655d 84 SUPERFAMILY SSF143011 3 79 5.3E-7 T 23-04-2016 DC74_RS17225 d5d6c043b479bcc17ecee447fb01402b 554 PIRSF PIRSF001423 1 553 3.6E-277 T 23-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 DC74_RS17225 d5d6c043b479bcc17ecee447fb01402b 554 Gene3D G3DSA:3.40.50.10730 137 343 2.7E-83 T 23-04-2016 DC74_RS17225 d5d6c043b479bcc17ecee447fb01402b 554 Pfam PF01175 Urocanase 7 541 2.1E-252 T 23-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 DC74_RS17225 d5d6c043b479bcc17ecee447fb01402b 554 ProSitePatterns PS01233 Urocanase signature. 436 451 - T 23-04-2016 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 DC74_RS17225 d5d6c043b479bcc17ecee447fb01402b 554 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 548 1.2E-272 T 23-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 DC74_RS17225 d5d6c043b479bcc17ecee447fb01402b 554 Hamap MF_00577 Urocanate hydratase [hutU]. 2 550 49.305 T 23-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 DC74_RS17225 d5d6c043b479bcc17ecee447fb01402b 554 PANTHER PTHR12216 5 550 0.0 T 23-04-2016 DC74_RS17225 d5d6c043b479bcc17ecee447fb01402b 554 PANTHER PTHR12216:SF3 5 550 0.0 T 23-04-2016 DC74_RS17225 d5d6c043b479bcc17ecee447fb01402b 554 SUPERFAMILY SSF111326 4 549 6.41E-247 T 23-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 DC74_RS17225 d5d6c043b479bcc17ecee447fb01402b 554 Gene3D G3DSA:3.40.1770.10 6 136 2.8E-153 T 23-04-2016 DC74_RS17225 d5d6c043b479bcc17ecee447fb01402b 554 Gene3D G3DSA:3.40.1770.10 354 548 2.8E-153 T 23-04-2016 DC74_RS26660 095bf46218fb7dd836be7be3470d55e6 190 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 135 181 2.4E-7 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS26660 095bf46218fb7dd836be7be3470d55e6 190 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 20 63 0.0089 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS26660 095bf46218fb7dd836be7be3470d55e6 190 Gene3D G3DSA:1.10.1780.10 77 181 2.5E-34 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS26660 095bf46218fb7dd836be7be3470d55e6 190 Gene3D G3DSA:1.10.1780.10 1 45 2.5E-34 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS26660 095bf46218fb7dd836be7be3470d55e6 190 SUPERFAMILY SSF81923 79 181 1.19E-8 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS26660 095bf46218fb7dd836be7be3470d55e6 190 SUPERFAMILY SSF81923 3 64 2.49E-6 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS36475 a5b099d20f613040b5c7a11d5148ff11 450 Gene3D G3DSA:1.20.1250.20 246 428 4.5E-17 T 23-04-2016 DC74_RS36475 a5b099d20f613040b5c7a11d5148ff11 450 Pfam PF07690 Major Facilitator Superfamily 42 281 2.0E-19 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS36475 a5b099d20f613040b5c7a11d5148ff11 450 Gene3D G3DSA:1.20.1250.20 35 224 8.0E-19 T 23-04-2016 DC74_RS36475 a5b099d20f613040b5c7a11d5148ff11 450 ProSitePatterns PS00216 Sugar transport proteins signature 1. 303 319 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS36475 a5b099d20f613040b5c7a11d5148ff11 450 PANTHER PTHR23518:SF2 27 443 6.1E-65 T 23-04-2016 DC74_RS36475 a5b099d20f613040b5c7a11d5148ff11 450 PANTHER PTHR23518 27 443 6.1E-65 T 23-04-2016 DC74_RS36475 a5b099d20f613040b5c7a11d5148ff11 450 SUPERFAMILY SSF103473 34 427 4.19E-47 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS37520 0a1f5b1f59508aa9566b00e8211ccc0c 222 Pfam PF13349 Putative adhesin 24 217 6.0E-9 T 23-04-2016 IPR025164 Putative adhesin DC74_RS25490 ba43256eb77e10f420d1cff2b2dd70cb 231 Pfam PF01464 Transglycosylase SLT domain 155 220 3.2E-7 T 23-04-2016 IPR008258 Transglycosylase SLT domain 1 DC74_RS25490 ba43256eb77e10f420d1cff2b2dd70cb 231 SUPERFAMILY SSF53955 159 225 2.86E-10 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS25490 ba43256eb77e10f420d1cff2b2dd70cb 231 Gene3D G3DSA:1.10.530.10 158 224 8.1E-7 T 23-04-2016 DC74_RS10160 6e4d9d120c4bf1b693f65279168b6c48 243 Gene3D G3DSA:1.10.10.10 21 89 1.0E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10160 6e4d9d120c4bf1b693f65279168b6c48 243 SMART SM00895 108 229 5.0E-18 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS10160 6e4d9d120c4bf1b693f65279168b6c48 243 SUPERFAMILY SSF46785 16 89 2.28E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10160 6e4d9d120c4bf1b693f65279168b6c48 243 Pfam PF07729 FCD domain 108 226 4.4E-18 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS10160 6e4d9d120c4bf1b693f65279168b6c48 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 85 1.2E-13 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10160 6e4d9d120c4bf1b693f65279168b6c48 243 SUPERFAMILY SSF48008 105 237 3.92E-22 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS10160 6e4d9d120c4bf1b693f65279168b6c48 243 Gene3D G3DSA:1.20.120.530 102 238 2.0E-20 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS10160 6e4d9d120c4bf1b693f65279168b6c48 243 SMART SM00345 24 85 3.3E-13 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10160 6e4d9d120c4bf1b693f65279168b6c48 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 7.8E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10160 6e4d9d120c4bf1b693f65279168b6c48 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 7.8E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS10160 6e4d9d120c4bf1b693f65279168b6c48 243 PANTHER PTHR11751 22 124 3.5E-21 T 23-04-2016 DC74_RS06285 ba635a76e77df9940b4cda067c138209 180 SUPERFAMILY SSF55729 7 174 2.66E-35 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06285 ba635a76e77df9940b4cda067c138209 180 Gene3D G3DSA:3.40.630.30 11 179 6.2E-41 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06285 ba635a76e77df9940b4cda067c138209 180 Pfam PF13302 Acetyltransferase (GNAT) domain 12 150 3.6E-17 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS06285 ba635a76e77df9940b4cda067c138209 180 PANTHER PTHR13256:SF22 11 179 1.5E-39 T 23-04-2016 DC74_RS06285 ba635a76e77df9940b4cda067c138209 180 PANTHER PTHR13256 11 179 1.5E-39 T 23-04-2016 DC74_RS19525 1965bda986aece2da51e514ebfcef4d2 186 SUPERFAMILY SSF46785 28 172 3.91E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19525 1965bda986aece2da51e514ebfcef4d2 186 Pfam PF12802 MarR family 59 118 5.2E-12 T 23-04-2016 DC74_RS19525 1965bda986aece2da51e514ebfcef4d2 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 113 7.8E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS19525 1965bda986aece2da51e514ebfcef4d2 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 7.8E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS19525 1965bda986aece2da51e514ebfcef4d2 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 147 167 7.8E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS19525 1965bda986aece2da51e514ebfcef4d2 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 133 7.8E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS19525 1965bda986aece2da51e514ebfcef4d2 186 PANTHER PTHR33164 7 181 7.5E-56 T 23-04-2016 DC74_RS19525 1965bda986aece2da51e514ebfcef4d2 186 ProSitePatterns PS00519 AsnC-type HTH domain signature. 82 108 - T 23-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site DC74_RS19525 1965bda986aece2da51e514ebfcef4d2 186 Gene3D G3DSA:1.10.10.10 23 173 9.3E-35 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19525 1965bda986aece2da51e514ebfcef4d2 186 PANTHER PTHR33164:SF4 7 181 7.5E-56 T 23-04-2016 DC74_RS19525 1965bda986aece2da51e514ebfcef4d2 186 SMART SM00347 54 157 1.8E-21 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS02650 15430c345167dfe1e466430a22d1c186 303 SUPERFAMILY SSF47413 28 86 1.54E-5 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS02650 15430c345167dfe1e466430a22d1c186 303 Gene3D G3DSA:1.10.260.40 26 86 1.5E-5 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS02650 15430c345167dfe1e466430a22d1c186 303 SMART SM00530 34 89 0.0045 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS02650 15430c345167dfe1e466430a22d1c186 303 PANTHER PTHR10245:SF20 2 303 1.6E-90 T 23-04-2016 DC74_RS02650 15430c345167dfe1e466430a22d1c186 303 PANTHER PTHR10245 2 303 1.6E-90 T 23-04-2016 DC74_RS02650 15430c345167dfe1e466430a22d1c186 303 Pfam PF13560 Helix-turn-helix domain 31 91 2.2E-11 T 23-04-2016 DC74_RS06385 ff529848715ed94f765336a52834d7d9 508 SUPERFAMILY SSF51445 18 334 5.47E-79 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS06385 ff529848715ed94f765336a52834d7d9 508 PANTHER PTHR30480 10 339 3.2E-114 T 23-04-2016 DC74_RS06385 ff529848715ed94f765336a52834d7d9 508 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 39 327 2.3E-76 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS06385 ff529848715ed94f765336a52834d7d9 508 Gene3D G3DSA:3.20.20.300 18 330 4.6E-89 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS06385 ff529848715ed94f765336a52834d7d9 508 PANTHER PTHR30480:SF2 10 339 3.2E-114 T 23-04-2016 DC74_RS18660 def622914f0f4ccd96aaabf63fe28b73 127 Gene3D G3DSA:3.30.420.100 31 127 1.2E-37 T 23-04-2016 DC74_RS18660 def622914f0f4ccd96aaabf63fe28b73 127 PANTHER PTHR12899 14 127 8.8E-39 T 23-04-2016 DC74_RS18660 def622914f0f4ccd96aaabf63fe28b73 127 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 13 127 26.593 T 23-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18660 def622914f0f4ccd96aaabf63fe28b73 127 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 13 127 2.9E-48 T 23-04-2016 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18660 def622914f0f4ccd96aaabf63fe28b73 127 SUPERFAMILY SSF53137 14 125 4.14E-46 T 23-04-2016 DC74_RS18660 def622914f0f4ccd96aaabf63fe28b73 127 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 15 127 2.9E-39 T 23-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS09815 c836883f70d848c9519bc734c80b18f7 211 SUPERFAMILY SSF55729 7 175 1.97E-36 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS09815 c836883f70d848c9519bc734c80b18f7 211 Pfam PF13302 Acetyltransferase (GNAT) domain 14 154 4.5E-27 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS09815 c836883f70d848c9519bc734c80b18f7 211 Gene3D G3DSA:3.40.630.30 8 192 5.0E-47 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS09815 c836883f70d848c9519bc734c80b18f7 211 PANTHER PTHR13256:SF21 6 211 3.4E-56 T 23-04-2016 DC74_RS09815 c836883f70d848c9519bc734c80b18f7 211 PANTHER PTHR13256 6 211 3.4E-56 T 23-04-2016 DC74_RS01430 36b0a8ccd3c35b56c01e85c8d01bdbbe 193 SUPERFAMILY SSF88946 16 114 6.28E-30 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS01430 36b0a8ccd3c35b56c01e85c8d01bdbbe 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 188 9.9E-30 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS01430 36b0a8ccd3c35b56c01e85c8d01bdbbe 193 Pfam PF08281 Sigma-70, region 4 135 185 4.6E-11 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS01430 36b0a8ccd3c35b56c01e85c8d01bdbbe 193 PANTHER PTHR30173 8 193 1.5E-45 T 23-04-2016 DC74_RS01430 36b0a8ccd3c35b56c01e85c8d01bdbbe 193 SUPERFAMILY SSF88659 116 191 3.36E-13 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS01430 36b0a8ccd3c35b56c01e85c8d01bdbbe 193 Gene3D G3DSA:1.10.10.10 127 190 9.5E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01430 36b0a8ccd3c35b56c01e85c8d01bdbbe 193 Pfam PF04542 Sigma-70 region 2 37 103 2.0E-20 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS01430 36b0a8ccd3c35b56c01e85c8d01bdbbe 193 Gene3D G3DSA:1.10.1740.10 17 124 2.0E-33 T 23-04-2016 DC74_RS19830 ca66bdf5c373bbfb461f10eff6419c14 325 SMART SM00382 35 213 3.6E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS19830 ca66bdf5c373bbfb461f10eff6419c14 325 PANTHER PTHR24220:SF160 12 235 1.0E-98 T 23-04-2016 DC74_RS19830 ca66bdf5c373bbfb461f10eff6419c14 325 Pfam PF00005 ABC transporter 26 165 3.3E-24 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS19830 ca66bdf5c373bbfb461f10eff6419c14 325 SUPERFAMILY SSF52540 9 225 2.27E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19830 ca66bdf5c373bbfb461f10eff6419c14 325 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS19830 ca66bdf5c373bbfb461f10eff6419c14 325 PANTHER PTHR24220 12 235 1.0E-98 T 23-04-2016 DC74_RS19830 ca66bdf5c373bbfb461f10eff6419c14 325 Gene3D G3DSA:3.40.50.300 9 225 6.0E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 PANTHER PTHR19375:SF117 10 326 5.6E-61 T 23-04-2016 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 Gene3D G3DSA:3.30.420.40 161 187 2.3E-23 T 23-04-2016 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 Gene3D G3DSA:3.30.420.40 263 317 2.3E-23 T 23-04-2016 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 SUPERFAMILY SSF53067 150 327 5.25E-29 T 23-04-2016 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 SUPERFAMILY SSF53067 13 149 3.24E-19 T 23-04-2016 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 1.2E-33 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 48 66 1.2E-33 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 1.2E-33 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 300 326 1.2E-33 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 68 91 1.2E-33 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 Pfam PF06723 MreB/Mbl protein 12 331 2.3E-103 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 PANTHER PTHR19375 10 326 5.6E-61 T 23-04-2016 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 Gene3D G3DSA:3.30.420.40 14 160 1.4E-20 T 23-04-2016 DC74_RS14190 f1408524b18ecd9042caa39495b181f2 343 Gene3D G3DSA:3.90.640.10 188 257 1.6E-9 T 23-04-2016 DC74_RS37100 52ac8984cfe6d230fa2922838cc06bbf 216 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 150 1.9E-7 T 23-04-2016 IPR001451 Hexapeptide repeat DC74_RS37100 52ac8984cfe6d230fa2922838cc06bbf 216 PANTHER PTHR23416:SF69 37 210 6.2E-59 T 23-04-2016 DC74_RS37100 52ac8984cfe6d230fa2922838cc06bbf 216 Gene3D G3DSA:2.160.10.10 34 211 1.8E-43 T 23-04-2016 DC74_RS37100 52ac8984cfe6d230fa2922838cc06bbf 216 SUPERFAMILY SSF51161 60 208 1.12E-39 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS37100 52ac8984cfe6d230fa2922838cc06bbf 216 PANTHER PTHR23416 37 210 6.2E-59 T 23-04-2016 DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 Gene3D G3DSA:3.40.50.300 294 310 5.4E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 Gene3D G3DSA:3.40.50.300 62 255 5.4E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 SUPERFAMILY SSF52540 58 402 3.16E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 SMART SM01086 317 411 6.5E-30 T 23-04-2016 IPR019489 Clp ATPase, C-terminal DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 2.1E-194 T 23-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 Gene3D G3DSA:1.10.8.60 316 413 2.0E-34 T 23-04-2016 DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 Pfam PF06689 ClpX C4-type zinc finger 11 48 8.9E-21 T 23-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 SUPERFAMILY SSF57716 11 46 1.37E-11 T 23-04-2016 DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 SMART SM00994 10 49 1.1E-23 T 23-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 PANTHER PTHR11262 5 412 1.8E-239 T 23-04-2016 DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 SMART SM00382 113 266 3.3E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.086 T 23-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 310 3.5E-50 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS15315 5a03e469ac18315003ed81abc569d02c 427 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 394 1.2E-14 T 23-04-2016 IPR019489 Clp ATPase, C-terminal DC74_RS08155 2f094006502d778d3b4e18b64a4dfa10 149 Gene3D G3DSA:2.70.70.10 3 148 3.4E-45 T 23-04-2016 DC74_RS08155 2f094006502d778d3b4e18b64a4dfa10 149 PANTHER PTHR30175 6 99 3.4E-29 T 23-04-2016 DC74_RS08155 2f094006502d778d3b4e18b64a4dfa10 149 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 3 124 1.0E-37 T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- DC74_RS08155 2f094006502d778d3b4e18b64a4dfa10 149 SUPERFAMILY SSF51261 3 146 8.72E-36 T 23-04-2016 IPR011055 Duplicated hybrid motif DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 381 394 - T 23-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 SMART SM00962 209 408 7.9E-102 T 23-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 SUPERFAMILY SSF52540 209 407 6.29E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 Gene3D G3DSA:1.20.120.140 132 221 1.3E-26 T 23-04-2016 DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 SUPERFAMILY SSF47364 103 181 6.54E-19 T 23-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 Pfam PF00448 SRP54-type protein, GTPase domain 210 407 3.9E-72 T 23-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 PANTHER PTHR11564 97 407 3.5E-114 T 23-04-2016 DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 SMART SM00382 208 384 2.0E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 131 406 6.8E-101 T 23-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 130 408 57.224 T 23-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 SMART SM00963 107 187 2.3E-23 T 23-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 Pfam PF02881 SRP54-type protein, helical bundle domain 118 183 1.1E-13 T 23-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 Gene3D G3DSA:3.40.50.300 222 407 1.0E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28065 0e02970024ef1ab0c494ec4a4a9ab795 408 PANTHER PTHR11564:SF16 97 407 3.5E-114 T 23-04-2016 DC74_RS40235 a05352c6a033d379ec1ef132a8f8f1fd 480 Gene3D G3DSA:1.25.40.10 182 249 1.7E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS40235 a05352c6a033d379ec1ef132a8f8f1fd 480 Gene3D G3DSA:1.25.40.10 330 432 1.7E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS40235 a05352c6a033d379ec1ef132a8f8f1fd 480 PANTHER PTHR35807 1 218 1.6E-14 T 23-04-2016 DC74_RS40235 a05352c6a033d379ec1ef132a8f8f1fd 480 SUPERFAMILY SSF48452 181 290 9.1E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS40235 a05352c6a033d379ec1ef132a8f8f1fd 480 SUPERFAMILY SSF46894 2 79 2.49E-6 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS34820 b0d4483bf0a522d274971ec17bcfffb6 554 Pfam PF00795 Carbon-nitrogen hydrolase 255 511 1.8E-20 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS34820 b0d4483bf0a522d274971ec17bcfffb6 554 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 94 490 1.0E-74 T 23-04-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 DC74_RS34820 b0d4483bf0a522d274971ec17bcfffb6 554 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 45 528 16.893 T 23-04-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 DC74_RS34820 b0d4483bf0a522d274971ec17bcfffb6 554 PANTHER PTHR38686 37 547 3.1E-55 T 23-04-2016 DC74_RS34820 b0d4483bf0a522d274971ec17bcfffb6 554 SUPERFAMILY SSF56317 249 520 2.09E-42 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS34820 b0d4483bf0a522d274971ec17bcfffb6 554 Gene3D G3DSA:3.60.110.10 247 516 1.6E-33 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS06260 bd45807d88011135244b9d9a2a854519 188 PANTHER PTHR11079 3 67 2.0E-35 T 23-04-2016 DC74_RS06260 bd45807d88011135244b9d9a2a854519 188 PANTHER PTHR11079 100 151 2.0E-35 T 23-04-2016 DC74_RS06260 bd45807d88011135244b9d9a2a854519 188 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 133 4.9E-17 T 23-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 DC74_RS06260 bd45807d88011135244b9d9a2a854519 188 Gene3D G3DSA:3.40.140.10 3 167 3.5E-44 T 23-04-2016 DC74_RS06260 bd45807d88011135244b9d9a2a854519 188 PANTHER PTHR11079:SF25 3 67 2.0E-35 T 23-04-2016 DC74_RS06260 bd45807d88011135244b9d9a2a854519 188 PANTHER PTHR11079:SF25 100 151 2.0E-35 T 23-04-2016 DC74_RS06260 bd45807d88011135244b9d9a2a854519 188 SUPERFAMILY SSF53927 3 73 4.07E-36 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS06260 bd45807d88011135244b9d9a2a854519 188 SUPERFAMILY SSF53927 101 176 4.07E-36 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PANTHER PTHR10992:SF778 157 285 2.4E-45 T 23-04-2016 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PANTHER PTHR10992:SF778 5 141 2.4E-45 T 23-04-2016 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PRINTS PR00412 Epoxide hydrolase signature 260 282 1.2E-18 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PRINTS PR00412 Epoxide hydrolase signature 37 55 1.2E-18 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PRINTS PR00412 Epoxide hydrolase signature 226 242 1.2E-18 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PRINTS PR00412 Epoxide hydrolase signature 103 116 1.2E-18 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PRINTS PR00412 Epoxide hydrolase signature 57 72 1.2E-18 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PRINTS PR00412 Epoxide hydrolase signature 117 130 1.2E-18 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 Gene3D G3DSA:3.40.50.1820 5 284 2.8E-63 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PANTHER PTHR10992 157 285 2.4E-45 T 23-04-2016 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PANTHER PTHR10992 5 141 2.4E-45 T 23-04-2016 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 3.4E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 3.4E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 228 242 3.4E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 3.4E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 SUPERFAMILY SSF53474 13 284 9.09E-56 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08225 5c4f344ad8ae5b086a527771943b99bb 289 Pfam PF00561 alpha/beta hydrolase fold 32 267 4.4E-24 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 404 413 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 PANTHER PTHR24291:SF46 1 462 2.2E-83 T 23-04-2016 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 PRINTS PR00385 P450 superfamily signature 402 411 5.6E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 PRINTS PR00385 P450 superfamily signature 329 340 5.6E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 PRINTS PR00385 P450 superfamily signature 411 422 5.6E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 PRINTS PR00385 P450 superfamily signature 276 293 5.6E-11 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 Pfam PF00067 Cytochrome P450 36 439 6.4E-74 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 SUPERFAMILY SSF48264 12 462 5.11E-103 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 Gene3D G3DSA:1.10.630.10 12 462 2.3E-104 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 PANTHER PTHR24291 1 462 2.2E-83 T 23-04-2016 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 PRINTS PR00463 E-class P450 group I signature 368 392 3.3E-14 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 PRINTS PR00463 E-class P450 group I signature 411 434 3.3E-14 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 PRINTS PR00463 E-class P450 group I signature 401 411 3.3E-14 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 PRINTS PR00463 E-class P450 group I signature 285 311 3.3E-14 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS27040 686eaebe02f4f8d3e597a6c697c6398c 462 PRINTS PR00463 E-class P450 group I signature 265 282 3.3E-14 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 SUPERFAMILY SSF52540 794 1034 2.37E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 SMART SM00382 466 645 2.6 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 SMART SM00382 822 998 2.3 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 SMART SM00382 1108 1245 0.5 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 Gene3D G3DSA:3.40.50.300 438 624 4.3E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 Gene3D G3DSA:3.40.50.300 816 1003 7.0E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 PANTHER PTHR22683 8 691 5.7E-261 T 23-04-2016 DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 PANTHER PTHR22683 1221 1312 5.7E-261 T 23-04-2016 DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 741 1311 2.7E-229 T 23-04-2016 IPR023837 EccCb-like, Actinobacteria DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 Gene3D G3DSA:3.40.50.300 1104 1139 1.4E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 SUPERFAMILY SSF52540 430 640 5.15E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 689 1.7E-253 T 23-04-2016 IPR023836 EccCa-like, Actinobacteria DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 PANTHER PTHR22683:SF1 8 691 5.7E-261 T 23-04-2016 DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 PANTHER PTHR22683:SF1 886 1171 5.7E-261 T 23-04-2016 DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 PANTHER PTHR22683:SF1 1221 1312 5.7E-261 T 23-04-2016 DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 Pfam PF01580 FtsK/SpoIIIE family 804 1020 3.2E-45 T 23-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 Pfam PF01580 FtsK/SpoIIIE family 437 565 6.6E-24 T 23-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 PANTHER PTHR22683 886 1171 5.7E-261 T 23-04-2016 DC74_RS28560 6f3fb93b263200ccaf0f1ee0dd8f2304 1319 SUPERFAMILY SSF52540 1071 1246 6.31E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS01145 670ed71bc24fa7635de0c99997d60a53 339 PANTHER PTHR11695 29 335 3.8E-46 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS01145 670ed71bc24fa7635de0c99997d60a53 339 SMART SM00829 23 335 6.8E-4 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS01145 670ed71bc24fa7635de0c99997d60a53 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 43 102 8.0E-9 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS01145 670ed71bc24fa7635de0c99997d60a53 339 Pfam PF13602 Zinc-binding dehydrogenase 210 335 1.1E-6 T 23-04-2016 DC74_RS01145 670ed71bc24fa7635de0c99997d60a53 339 SUPERFAMILY SSF50129 15 151 7.0E-29 T 23-04-2016 IPR011032 GroES-like DC74_RS01145 670ed71bc24fa7635de0c99997d60a53 339 SUPERFAMILY SSF51735 127 261 5.11E-19 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01145 670ed71bc24fa7635de0c99997d60a53 339 Gene3D G3DSA:3.90.180.10 16 162 1.0E-29 T 23-04-2016 IPR011032 GroES-like DC74_RS01145 670ed71bc24fa7635de0c99997d60a53 339 Gene3D G3DSA:3.40.50.720 163 280 1.1E-14 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01145 670ed71bc24fa7635de0c99997d60a53 339 PANTHER PTHR11695:SF5 29 335 3.8E-46 T 23-04-2016 DC74_RS24450 cebd4c190df9c88c9c14b363e01644c1 133 Pfam PF04965 Gene 25-like lysozyme 33 119 4.1E-18 T 23-04-2016 IPR007048 GpW/Gp25/anti-adapter protein IraD DC74_RS24450 cebd4c190df9c88c9c14b363e01644c1 133 PANTHER PTHR35862 14 127 1.0E-27 T 23-04-2016 DC74_RS24450 cebd4c190df9c88c9c14b363e01644c1 133 SUPERFAMILY SSF160719 31 127 5.36E-22 T 23-04-2016 DC74_RS24450 cebd4c190df9c88c9c14b363e01644c1 133 Gene3D G3DSA:3.10.450.40 12 127 8.4E-32 T 23-04-2016 DC74_RS24450 cebd4c190df9c88c9c14b363e01644c1 133 PANTHER PTHR35862:SF2 14 127 1.0E-27 T 23-04-2016 DC74_RS08835 87b799a5790e9ee2f3bbe226407fec50 251 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 17 129 7.5E-18 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS08835 87b799a5790e9ee2f3bbe226407fec50 251 Pfam PF07398 MDMPI C-terminal domain 144 243 2.3E-17 T 23-04-2016 IPR010872 MDMPI C-terminal DC74_RS08835 87b799a5790e9ee2f3bbe226407fec50 251 SUPERFAMILY SSF109854 18 135 1.1E-6 T 23-04-2016 DC74_RS08835 87b799a5790e9ee2f3bbe226407fec50 251 PANTHER PTHR40758 1 251 8.7E-63 T 23-04-2016 DC74_RS08835 87b799a5790e9ee2f3bbe226407fec50 251 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 16 227 5.3E-24 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS23440 efba3c85b3c7b0154e942c659700a74d 431 SUPERFAMILY SSF52266 223 426 8.55E-44 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS23440 efba3c85b3c7b0154e942c659700a74d 431 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 227 421 1.3E-26 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS23440 efba3c85b3c7b0154e942c659700a74d 431 Gene3D G3DSA:3.40.50.1110 224 426 1.9E-28 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS23440 efba3c85b3c7b0154e942c659700a74d 431 PANTHER PTHR30383 70 428 2.0E-86 T 23-04-2016 DC74_RS23440 efba3c85b3c7b0154e942c659700a74d 431 PANTHER PTHR30383:SF3 70 428 2.0E-86 T 23-04-2016 DC74_RS32525 09ad667337d631b2d38fd6595a6e3789 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 38 147 1.8E-30 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS32525 09ad667337d631b2d38fd6595a6e3789 345 PANTHER PTHR11695:SF451 25 344 2.0E-115 T 23-04-2016 DC74_RS32525 09ad667337d631b2d38fd6595a6e3789 345 SMART SM00829 23 343 0.0052 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS32525 09ad667337d631b2d38fd6595a6e3789 345 PANTHER PTHR11695 25 344 2.0E-115 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS32525 09ad667337d631b2d38fd6595a6e3789 345 SUPERFAMILY SSF51735 153 312 7.89E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32525 09ad667337d631b2d38fd6595a6e3789 345 SUPERFAMILY SSF50129 13 186 9.74E-57 T 23-04-2016 IPR011032 GroES-like DC74_RS32525 09ad667337d631b2d38fd6595a6e3789 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 74 88 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS32525 09ad667337d631b2d38fd6595a6e3789 345 Pfam PF00107 Zinc-binding dehydrogenase 188 303 3.5E-19 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS32525 09ad667337d631b2d38fd6595a6e3789 345 Gene3D G3DSA:3.90.180.10 8 179 9.9E-58 T 23-04-2016 IPR011032 GroES-like DC74_RS32525 09ad667337d631b2d38fd6595a6e3789 345 Gene3D G3DSA:3.40.50.720 180 293 1.8E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38760 440dc5a3c81fde6ce73107e2ad6e4258 249 Gene3D G3DSA:3.40.50.1820 9 245 1.1E-38 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS38760 440dc5a3c81fde6ce73107e2ad6e4258 249 Pfam PF00975 Thioesterase domain 23 243 2.9E-59 T 23-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 DC74_RS38760 440dc5a3c81fde6ce73107e2ad6e4258 249 SUPERFAMILY SSF53474 10 247 9.1E-55 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS38760 440dc5a3c81fde6ce73107e2ad6e4258 249 PANTHER PTHR11487 10 246 2.6E-81 T 23-04-2016 IPR012223 Thioesterase type II, NRPS/PKS/S-FAS GO:0009058 DC74_RS38760 440dc5a3c81fde6ce73107e2ad6e4258 249 SMART SM00824 Thioesterase 25 247 0.0024 T 23-04-2016 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 PANTHER PTHR10242:SF3 261 488 5.1E-106 T 23-04-2016 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 PANTHER PTHR10242:SF3 196 242 5.1E-106 T 23-04-2016 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 SMART SM00478 324 481 4.5E-27 T 23-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 Pfam PF12833 Helix-turn-helix domain 106 185 2.0E-18 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 Pfam PF06029 AlkA N-terminal domain 199 314 1.3E-30 T 23-04-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 Gene3D G3DSA:1.10.10.60 138 187 1.5E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 SUPERFAMILY SSF55945 199 295 7.38E-26 T 23-04-2016 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 SUPERFAMILY SSF57884 2 82 4.32E-32 T 23-04-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 Gene3D G3DSA:1.10.340.30 317 431 2.4E-36 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 Gene3D G3DSA:1.10.10.60 83 137 3.2E-5 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 Gene3D G3DSA:1.10.1670.10 432 485 1.1E-16 T 23-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 Gene3D G3DSA:3.30.310.20 199 314 7.9E-35 T 23-04-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 PANTHER PTHR10242 261 488 5.1E-106 T 23-04-2016 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 PANTHER PTHR10242 196 242 5.1E-106 T 23-04-2016 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 Pfam PF02805 Metal binding domain of Ada 8 71 3.1E-29 T 23-04-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 SMART SM01009 199 314 1.6E-46 T 23-04-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 SMART SM00342 100 183 3.1E-19 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 Gene3D G3DSA:3.40.10.10 2 82 5.0E-35 T 23-04-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 SUPERFAMILY SSF48150 303 479 1.73E-42 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS31710 39e2363f50fde81133bac4e1f10a486f 490 SUPERFAMILY SSF46689 137 187 1.88E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS18375 d48d3a6047199c4b5959b1f74a6e47ee 313 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 198 7.1E-5 T 23-04-2016 DC74_RS18375 d48d3a6047199c4b5959b1f74a6e47ee 313 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 242 1.6E-35 T 23-04-2016 DC74_RS18375 d48d3a6047199c4b5959b1f74a6e47ee 313 Gene3D G3DSA:3.40.50.720 3 251 2.6E-61 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18375 d48d3a6047199c4b5959b1f74a6e47ee 313 PANTHER PTHR13078:SF55 53 281 4.6E-39 T 23-04-2016 DC74_RS18375 d48d3a6047199c4b5959b1f74a6e47ee 313 SUPERFAMILY SSF51735 5 248 1.43E-55 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18375 d48d3a6047199c4b5959b1f74a6e47ee 313 PANTHER PTHR13078 53 281 4.6E-39 T 23-04-2016 DC74_RS18375 d48d3a6047199c4b5959b1f74a6e47ee 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 2.9E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18375 d48d3a6047199c4b5959b1f74a6e47ee 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 2.9E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18375 d48d3a6047199c4b5959b1f74a6e47ee 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 2.9E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18375 d48d3a6047199c4b5959b1f74a6e47ee 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.9E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18375 d48d3a6047199c4b5959b1f74a6e47ee 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 2.9E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18375 d48d3a6047199c4b5959b1f74a6e47ee 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 2.9E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS15835 188c110facbb9bf651d57916a3701646 539 Gene3D G3DSA:3.40.50.970 358 524 9.9E-45 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS15835 188c110facbb9bf651d57916a3701646 539 Gene3D G3DSA:3.40.50.970 2 173 6.0E-46 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS15835 188c110facbb9bf651d57916a3701646 539 PANTHER PTHR18968 1 523 1.7E-143 T 23-04-2016 DC74_RS15835 188c110facbb9bf651d57916a3701646 539 SUPERFAMILY SSF52518 2 174 9.06E-39 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS15835 188c110facbb9bf651d57916a3701646 539 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 524 2.6E-32 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS15835 188c110facbb9bf651d57916a3701646 539 Gene3D G3DSA:3.40.50.1220 179 323 6.2E-43 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS15835 188c110facbb9bf651d57916a3701646 539 SUPERFAMILY SSF52518 360 527 5.54E-43 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS15835 188c110facbb9bf651d57916a3701646 539 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2 167 2.5E-43 T 23-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DC74_RS15835 188c110facbb9bf651d57916a3701646 539 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 186 317 3.5E-30 T 23-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DC74_RS15835 188c110facbb9bf651d57916a3701646 539 SUPERFAMILY SSF52467 150 324 1.39E-35 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS15835 188c110facbb9bf651d57916a3701646 539 PANTHER PTHR18968:SF116 1 523 1.7E-143 T 23-04-2016 DC74_RS15835 188c110facbb9bf651d57916a3701646 539 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 415 434 - T 23-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 PANTHER PTHR23389 536 585 2.1E-168 T 23-04-2016 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 Gene3D G3DSA:2.40.50.140 337 407 3.6E-26 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 SUPERFAMILY SSF52113 646 722 6.73E-18 T 23-04-2016 IPR001357 BRCT domain DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 SUPERFAMILY SSF47781 420 513 1.71E-44 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 SUPERFAMILY SSF47781 544 637 1.71E-44 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 PANTHER PTHR23389:SF9 536 585 2.1E-168 T 23-04-2016 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 SUPERFAMILY SSF50249 335 417 2.57E-24 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 PIRSF PIRSF001604 8 724 8.2E-235 T 23-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 Gene3D G3DSA:1.10.287.610 12 78 2.3E-27 T 23-04-2016 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 23 507 7.2E-171 T 23-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 Gene3D G3DSA:1.10.150.20 557 638 2.2E-28 T 23-04-2016 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 348 363 - T 23-04-2016 IPR033136 NAD-dependent DNA ligase, conserved site DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 Gene3D G3DSA:3.40.50.10190 646 723 1.2E-23 T 23-04-2016 IPR001357 BRCT domain DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 339 415 9.5E-28 T 23-04-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 16 335 3.6E-120 T 23-04-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 SMART SM00532 15 466 7.8E-257 T 23-04-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 Gene3D G3DSA:3.30.470.30 134 266 1.2E-50 T 23-04-2016 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 Hamap MF_01588 DNA ligase [ligA]. 14 720 50.819 T 23-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 647 715 9.0E-12 T 23-04-2016 IPR001357 BRCT domain DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 SUPERFAMILY SSF56091 14 335 2.67E-110 T 23-04-2016 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 PANTHER PTHR23389 4 505 2.1E-168 T 23-04-2016 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 Gene3D G3DSA:1.10.150.20 453 509 3.1E-5 T 23-04-2016 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 SMART SM00292 646 723 3.5E-10 T 23-04-2016 IPR001357 BRCT domain DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 424 452 1.7E-8 T 23-04-2016 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 130 159 - T 23-04-2016 IPR018239 NAD-dependent DNA ligase, active site DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 PANTHER PTHR23389:SF9 4 505 2.1E-168 T 23-04-2016 DC74_RS27580 aaff67b3d63967c246446abb86a3fd9b 738 Pfam PF12826 Helix-hairpin-helix motif 563 626 6.2E-22 T 23-04-2016 DC74_RS13830 f2bc431db0ae13ee95ebf6dfe04659f8 391 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 279 285 - T 23-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 DC74_RS13830 f2bc431db0ae13ee95ebf6dfe04659f8 391 PANTHER PTHR18895 217 380 4.9E-21 T 23-04-2016 DC74_RS13830 f2bc431db0ae13ee95ebf6dfe04659f8 391 SUPERFAMILY SSF53335 183 328 9.18E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS13830 f2bc431db0ae13ee95ebf6dfe04659f8 391 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 212 282 7.7E-11 T 23-04-2016 DC74_RS13830 f2bc431db0ae13ee95ebf6dfe04659f8 391 Gene3D G3DSA:3.40.50.150 172 334 1.1E-32 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.6E-51 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.6E-51 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.6E-51 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.6E-51 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 322 1.9E-128 T 23-04-2016 IPR000158 Cell division protein FtsZ GO:0005525 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 PANTHER PTHR30314:SF3 5 337 9.0E-194 T 23-04-2016 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 PANTHER PTHR30314 5 337 9.0E-194 T 23-04-2016 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 170 1.8E-37 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 Pfam PF12327 FtsZ family, C-terminal domain 219 313 4.7E-35 T 23-04-2016 IPR024757 Cell division protein FtsZ, C-terminal DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 SMART SM00864 10 202 5.2E-108 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 SMART SM00865 204 321 3.0E-57 T 23-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 23-04-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 SUPERFAMILY SSF55307 201 315 6.41E-44 T 23-04-2016 IPR008280 Tubulin/FtsZ, C-terminal DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 Gene3D G3DSA:3.40.50.1440 11 211 2.3E-91 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 23-04-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 Gene3D G3DSA:3.30.1330.20 212 314 3.3E-49 T 23-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 SUPERFAMILY SSF52490 9 205 3.01E-67 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 DC74_RS12530 e162a6223c58b3f5cefa7100b9994b95 413 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 380 38.867 T 23-04-2016 IPR000158 Cell division protein FtsZ GO:0005525 DC74_RS18325 1040434e083829f5fdc773d4a65541fc 162 Pfam PF00583 Acetyltransferase (GNAT) family 57 136 1.8E-10 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS18325 1040434e083829f5fdc773d4a65541fc 162 SUPERFAMILY SSF55729 2 159 1.7E-27 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS18325 1040434e083829f5fdc773d4a65541fc 162 PANTHER PTHR23091 1 162 5.3E-33 T 23-04-2016 DC74_RS18325 1040434e083829f5fdc773d4a65541fc 162 PANTHER PTHR23091:SF210 1 162 5.3E-33 T 23-04-2016 DC74_RS18325 1040434e083829f5fdc773d4a65541fc 162 Gene3D G3DSA:3.40.630.30 3 159 1.5E-30 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS29570 a6ac5e3443ed14a7eb80ad0aab2154a0 364 SUPERFAMILY SSF47413 3 63 9.05E-15 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS29570 a6ac5e3443ed14a7eb80ad0aab2154a0 364 Gene3D G3DSA:1.10.260.40 5 65 2.9E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS29570 a6ac5e3443ed14a7eb80ad0aab2154a0 364 SMART SM00530 6 61 3.7E-15 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS29570 a6ac5e3443ed14a7eb80ad0aab2154a0 364 Pfam PF01381 Helix-turn-helix 10 58 4.0E-13 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS29570 a6ac5e3443ed14a7eb80ad0aab2154a0 364 Pfam PF06114 Domain of unknown function (DUF955) 149 264 1.0E-15 T 23-04-2016 IPR010359 HTH domain, IrrE-type DC74_RS29570 a6ac5e3443ed14a7eb80ad0aab2154a0 364 PANTHER PTHR10245 6 116 9.1E-14 T 23-04-2016 DC74_RS03240 9b65eaae9aff97b8ccdef3bdbb6616a1 501 PANTHER PTHR11785:SF390 286 392 1.7E-44 T 23-04-2016 DC74_RS03240 9b65eaae9aff97b8ccdef3bdbb6616a1 501 PANTHER PTHR11785:SF390 19 262 1.7E-44 T 23-04-2016 DC74_RS03240 9b65eaae9aff97b8ccdef3bdbb6616a1 501 Pfam PF13520 Amino acid permease 3 421 6.9E-43 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS03240 9b65eaae9aff97b8ccdef3bdbb6616a1 501 PANTHER PTHR11785 286 392 1.7E-44 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS03240 9b65eaae9aff97b8ccdef3bdbb6616a1 501 PANTHER PTHR11785 19 262 1.7E-44 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS03240 9b65eaae9aff97b8ccdef3bdbb6616a1 501 PIRSF PIRSF006060 2 491 1.1E-54 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS06520 fc6340488a38869f1d8a1a66574f2cd1 250 PANTHER PTHR30328:SF17 6 124 6.2E-26 T 23-04-2016 DC74_RS06520 fc6340488a38869f1d8a1a66574f2cd1 250 SUPERFAMILY SSF48498 98 247 1.78E-22 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS06520 fc6340488a38869f1d8a1a66574f2cd1 250 Gene3D G3DSA:1.10.10.60 16 83 3.0E-23 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06520 fc6340488a38869f1d8a1a66574f2cd1 250 PANTHER PTHR30328 6 124 6.2E-26 T 23-04-2016 DC74_RS06520 fc6340488a38869f1d8a1a66574f2cd1 250 ProSitePatterns PS01081 TetR-type HTH domain signature. 46 77 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS06520 fc6340488a38869f1d8a1a66574f2cd1 250 SUPERFAMILY SSF46689 23 88 2.21E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06520 fc6340488a38869f1d8a1a66574f2cd1 250 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 94 242 1.4E-17 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS06520 fc6340488a38869f1d8a1a66574f2cd1 250 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 78 1.2E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS06520 fc6340488a38869f1d8a1a66574f2cd1 250 Gene3D G3DSA:1.10.357.10 84 242 8.9E-34 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS09485 e70cf3d9aa2f9d216fb08c301a74889a 180 SUPERFAMILY SSF52540 1 173 1.72E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09485 e70cf3d9aa2f9d216fb08c301a74889a 180 Pfam PF13671 AAA domain 1 133 8.3E-8 T 23-04-2016 DC74_RS09485 e70cf3d9aa2f9d216fb08c301a74889a 180 Gene3D G3DSA:3.40.50.300 1 173 8.9E-16 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21050 a72436ef8a5461f3bbdcae15b4db6e49 180 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 5 176 33.967 T 23-04-2016 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 DC74_RS21050 a72436ef8a5461f3bbdcae15b4db6e49 180 PANTHER PTHR12684 1 177 8.4E-58 T 23-04-2016 DC74_RS21050 a72436ef8a5461f3bbdcae15b4db6e49 180 PANTHER PTHR12684:SF2 1 177 8.4E-58 T 23-04-2016 DC74_RS21050 a72436ef8a5461f3bbdcae15b4db6e49 180 SUPERFAMILY SSF56399 7 177 6.04E-61 T 23-04-2016 DC74_RS21050 a72436ef8a5461f3bbdcae15b4db6e49 180 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 5 169 1.6E-38 T 23-04-2016 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 DC74_RS04710 91167b7e3422b33f20ae12bd0639860d 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 157 3.0E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04710 91167b7e3422b33f20ae12bd0639860d 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 3.0E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04710 91167b7e3422b33f20ae12bd0639860d 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.0E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04710 91167b7e3422b33f20ae12bd0639860d 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 3.0E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04710 91167b7e3422b33f20ae12bd0639860d 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 176 3.0E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04710 91167b7e3422b33f20ae12bd0639860d 236 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 2.8E-57 T 23-04-2016 DC74_RS04710 91167b7e3422b33f20ae12bd0639860d 236 PANTHER PTHR24322 8 169 2.1E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04710 91167b7e3422b33f20ae12bd0639860d 236 Gene3D G3DSA:3.40.50.720 5 230 5.0E-67 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04710 91167b7e3422b33f20ae12bd0639860d 236 SUPERFAMILY SSF51735 6 230 7.88E-68 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11860 6eebadacfae8eecb959627f2aa3565b0 203 Pfam PF12385 Papain-like cysteine protease AvrRpt2 47 186 2.1E-18 T 23-04-2016 IPR022118 Peptidase C70, AvrRpt2 KEGG: 00900+3.4.22.- DC74_RS20545 e7a4a7514e2129b897c1a3640e93e37c 272 Gene3D G3DSA:2.60.200.20 187 268 4.3E-24 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS20545 e7a4a7514e2129b897c1a3640e93e37c 272 SMART SM00240 198 247 9.8E-13 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS20545 e7a4a7514e2129b897c1a3640e93e37c 272 SUPERFAMILY SSF49879 150 268 2.1E-23 T 23-04-2016 IPR008984 SMAD/FHA domain GO:0005515 DC74_RS20545 e7a4a7514e2129b897c1a3640e93e37c 272 Pfam PF00498 FHA domain 200 261 3.6E-15 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS20545 e7a4a7514e2129b897c1a3640e93e37c 272 Pfam PF12401 Protein of unknown function (DUF2662) 4 118 2.1E-42 T 23-04-2016 IPR022128 Protein of unknown function DUF3662 DC74_RS05135 6013e51ee9edac5703b0110c2cc19f1f 529 PANTHER PTHR30093 6 79 2.7E-18 T 23-04-2016 DC74_RS05135 6013e51ee9edac5703b0110c2cc19f1f 529 Gene3D G3DSA:2.130.10.10 118 239 5.3E-12 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS05135 6013e51ee9edac5703b0110c2cc19f1f 529 Gene3D G3DSA:2.130.10.10 475 526 5.3E-12 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS05135 6013e51ee9edac5703b0110c2cc19f1f 529 Pfam PF13633 Prokaryotic N-terminal methylation site 15 37 2.5E-9 T 23-04-2016 IPR012902 Prokaryotic N-terminal methylation site DC74_RS05135 6013e51ee9edac5703b0110c2cc19f1f 529 Gene3D G3DSA:3.30.700.10 18 76 4.0E-8 T 23-04-2016 DC74_RS05135 6013e51ee9edac5703b0110c2cc19f1f 529 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 15 38 3.5E-9 T 23-04-2016 IPR012902 Prokaryotic N-terminal methylation site DC74_RS05135 6013e51ee9edac5703b0110c2cc19f1f 529 SUPERFAMILY SSF63825 127 277 1.65E-13 T 23-04-2016 DC74_RS05135 6013e51ee9edac5703b0110c2cc19f1f 529 PRINTS PR00885 Bacterial general secretion pathway protein H signature 13 27 2.2E-5 T 23-04-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 DC74_RS05135 6013e51ee9edac5703b0110c2cc19f1f 529 PRINTS PR00885 Bacterial general secretion pathway protein H signature 28 42 2.2E-5 T 23-04-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 DC74_RS05135 6013e51ee9edac5703b0110c2cc19f1f 529 SUPERFAMILY SSF54523 18 89 7.85E-16 T 23-04-2016 DC74_RS16290 029fc4f4e3649d338617096d7d39714a 100 Pfam PF00166 Chaperonin 10 Kd subunit 1 84 1.5E-18 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS16290 029fc4f4e3649d338617096d7d39714a 100 SMART SM00883 1 85 2.6E-21 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS16290 029fc4f4e3649d338617096d7d39714a 100 PANTHER PTHR10772 2 84 1.9E-19 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS16290 029fc4f4e3649d338617096d7d39714a 100 SUPERFAMILY SSF50129 2 85 3.46E-17 T 23-04-2016 IPR011032 GroES-like DC74_RS16290 029fc4f4e3649d338617096d7d39714a 100 Gene3D G3DSA:2.30.33.40 1 84 1.1E-18 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 SUPERFAMILY SSF55874 389 561 1.1E-39 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 SMART SM00388 332 399 2.6E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 SMART SM00387 445 560 4.5E-28 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 SMART SM00304 272 324 1.3E-9 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 SUPERFAMILY SSF47384 315 399 7.65E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 PANTHER PTHR24423 266 578 1.2E-197 T 23-04-2016 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 PANTHER PTHR24423 29 56 1.2E-197 T 23-04-2016 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 Pfam PF00512 His Kinase A (phospho-acceptor) domain 332 399 4.2E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 Pfam PF00672 HAMP domain 253 320 4.7E-11 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 PANTHER PTHR24423:SF500 266 578 1.2E-197 T 23-04-2016 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 PANTHER PTHR24423:SF500 29 56 1.2E-197 T 23-04-2016 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 SUPERFAMILY SSF158472 272 320 7.19E-6 T 23-04-2016 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 Gene3D G3DSA:3.30.565.10 402 560 4.6E-37 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 Gene3D G3DSA:1.10.287.130 323 395 3.8E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 538 1.7E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 513 1.7E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 557 1.7E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 499 1.7E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS16870 410ae900496dd32aadc19844cf3b6ba0 609 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 446 559 9.9E-18 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 ProSitePatterns PS00433 Phosphofructokinase signature. 266 284 - T 23-04-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 SUPERFAMILY SSF53784 1 332 1.01E-120 T 23-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 Pfam PF00365 Phosphofructokinase 2 297 3.5E-100 T 23-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 PIRSF PIRSF000532 1 340 7.5E-116 T 23-04-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 PANTHER PTHR13697 1 335 1.5E-133 T 23-04-2016 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 2.3E-74 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.3E-74 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.3E-74 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 2.3E-74 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 2.3E-74 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 2.3E-74 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 2.3E-74 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 2.3E-74 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 262 284 2.3E-74 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 323 1.4E-142 T 23-04-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 Gene3D G3DSA:3.40.50.450 1 213 2.3E-73 T 23-04-2016 DC74_RS27280 8958d9d6e0f21621ded5eb9753a7f046 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 42.818 T 23-04-2016 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS10030 84a7d599250a90fd9d13472ed0ca92da 597 SUPERFAMILY SSF52540 346 582 3.18E-77 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10030 84a7d599250a90fd9d13472ed0ca92da 597 Pfam PF00005 ABC transporter 365 514 2.8E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS10030 84a7d599250a90fd9d13472ed0ca92da 597 SUPERFAMILY SSF90123 23 331 2.88E-60 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS10030 84a7d599250a90fd9d13472ed0ca92da 597 Gene3D G3DSA:3.40.50.300 346 574 1.9E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10030 84a7d599250a90fd9d13472ed0ca92da 597 SMART SM00382 374 560 7.2E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS10030 84a7d599250a90fd9d13472ed0ca92da 597 Pfam PF00664 ABC transporter transmembrane region 35 302 4.3E-42 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS10030 84a7d599250a90fd9d13472ed0ca92da 597 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS10030 84a7d599250a90fd9d13472ed0ca92da 597 Gene3D G3DSA:1.20.1560.10 23 331 2.3E-62 T 23-04-2016 DC74_RS10030 84a7d599250a90fd9d13472ed0ca92da 597 PANTHER PTHR24221 23 593 6.7E-165 T 23-04-2016 DC74_RS24295 720be652c3fb89f8888f61b6644f6116 112 PANTHER PTHR10672 1 111 1.7E-45 T 23-04-2016 DC74_RS24295 720be652c3fb89f8888f61b6644f6116 112 Gene3D G3DSA:3.40.225.10 2 85 1.5E-23 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal DC74_RS24295 720be652c3fb89f8888f61b6644f6116 112 PANTHER PTHR10672:SF17 1 111 1.7E-45 T 23-04-2016 DC74_RS24295 720be652c3fb89f8888f61b6644f6116 112 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 14 63 1.2E-13 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal DC74_RS24295 720be652c3fb89f8888f61b6644f6116 112 SUPERFAMILY SSF53639 2 94 7.46E-26 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal DC74_RS08910 b46e244cbc7e6b1992db788dda83d693 168 Pfam PF01613 Flavin reductase like domain 23 166 3.8E-32 T 23-04-2016 IPR002563 Flavin reductase like domain GO:0010181 DC74_RS08910 b46e244cbc7e6b1992db788dda83d693 168 SUPERFAMILY SSF50475 14 164 2.01E-38 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS08910 b46e244cbc7e6b1992db788dda83d693 168 PANTHER PTHR30466:SF5 11 168 8.7E-69 T 23-04-2016 DC74_RS08910 b46e244cbc7e6b1992db788dda83d693 168 PANTHER PTHR30466 11 168 8.7E-69 T 23-04-2016 DC74_RS08910 b46e244cbc7e6b1992db788dda83d693 168 SMART SM00903 22 165 6.0E-46 T 23-04-2016 IPR002563 Flavin reductase like domain GO:0010181 DC74_RS08910 b46e244cbc7e6b1992db788dda83d693 168 Gene3D G3DSA:2.30.110.10 11 164 2.0E-51 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS15750 813f59a12cb240e5f832ddab857c5f55 183 Pfam PF13302 Acetyltransferase (GNAT) domain 17 150 6.6E-18 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS15750 813f59a12cb240e5f832ddab857c5f55 183 SUPERFAMILY SSF55729 16 154 1.29E-20 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS15750 813f59a12cb240e5f832ddab857c5f55 183 Gene3D G3DSA:3.40.630.30 16 171 9.4E-24 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS15750 813f59a12cb240e5f832ddab857c5f55 183 PANTHER PTHR13256 16 153 4.9E-15 T 23-04-2016 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 Gene3D G3DSA:1.10.3260.10 70 183 8.3E-17 T 23-04-2016 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 70 506 6.8E-72 T 23-04-2016 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 Reactome: REACT_216 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 SUPERFAMILY SSF117018 4 202 1.44E-25 T 23-04-2016 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 Gene3D G3DSA:2.40.50.140 388 507 5.8E-34 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 Hamap MF_00407 DNA ligase [lig]. 1 511 25.783 T 23-04-2016 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 Pfam PF01068 ATP dependent DNA ligase domain 186 385 9.8E-39 T 23-04-2016 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 Reactome: REACT_216 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 SUPERFAMILY SSF50249 387 507 1.71E-30 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 PANTHER PTHR10459:SF47 53 508 2.2E-211 T 23-04-2016 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 Pfam PF04675 DNA ligase N terminus 72 136 2.0E-6 T 23-04-2016 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 Gene3D G3DSA:3.30.1490.70 331 381 2.1E-17 T 23-04-2016 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 Gene3D G3DSA:3.30.1490.70 184 212 2.1E-17 T 23-04-2016 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 Gene3D G3DSA:3.30.470.30 213 328 1.0E-26 T 23-04-2016 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 SUPERFAMILY SSF56091 180 385 1.34E-43 T 23-04-2016 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 Pfam PF04679 ATP dependent DNA ligase C terminal region 404 495 3.3E-14 T 23-04-2016 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 Reactome: REACT_216 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 PANTHER PTHR10459 53 508 2.2E-211 T 23-04-2016 DC74_RS08645 e70e2e03d9ac4f92af1b00c9e376f16c 511 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 208 216 - T 23-04-2016 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 Reactome: REACT_216 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 87 100 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 SUPERFAMILY SSF88659 136 203 1.05E-13 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 59 280 2.1E-34 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 57 281 1.6E-90 T 23-04-2016 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 SUPERFAMILY SSF88946 23 132 1.09E-33 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 Gene3D G3DSA:1.10.10.10 131 186 8.2E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 PANTHER PTHR30385 2 285 1.1E-103 T 23-04-2016 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 SUPERFAMILY SSF88659 216 282 7.48E-16 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 PANTHER PTHR30385:SF4 2 285 1.1E-103 T 23-04-2016 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 Pfam PF04542 Sigma-70 region 2 63 132 1.5E-18 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 PRINTS PR00046 Major sigma-70 factor signature 267 278 1.9E-12 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 PRINTS PR00046 Major sigma-70 factor signature 252 267 1.9E-12 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 PRINTS PR00046 Major sigma-70 factor signature 235 247 1.9E-12 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 PRINTS PR00046 Major sigma-70 factor signature 87 100 1.9E-12 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 PRINTS PR00046 Major sigma-70 factor signature 111 119 1.9E-12 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 Pfam PF04539 Sigma-70 region 3 142 208 2.1E-10 T 23-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 Pfam PF04545 Sigma-70, region 4 231 279 3.0E-17 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 Gene3D G3DSA:1.10.601.10 40 130 1.3E-28 T 23-04-2016 DC74_RS03730 1b01d50fcbbd2e602ce45238e62bd6fa 294 Gene3D G3DSA:1.10.10.10 228 282 5.0E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06290 36d34461922e828ad597bc53acbac209 201 Gene3D G3DSA:1.10.357.10 4 195 1.9E-42 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS06290 36d34461922e828ad597bc53acbac209 201 SUPERFAMILY SSF46689 5 67 6.98E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06290 36d34461922e828ad597bc53acbac209 201 SUPERFAMILY SSF48498 81 196 1.19E-20 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS06290 36d34461922e828ad597bc53acbac209 201 Pfam PF13977 Bacterial transcriptional repressor 84 195 2.8E-20 T 23-04-2016 DC74_RS06290 36d34461922e828ad597bc53acbac209 201 PANTHER PTHR30328:SF23 8 195 2.0E-37 T 23-04-2016 DC74_RS06290 36d34461922e828ad597bc53acbac209 201 PANTHER PTHR30328 8 195 2.0E-37 T 23-04-2016 DC74_RS06290 36d34461922e828ad597bc53acbac209 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 61 9.6E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS25825 165bbf019f2535351cd4f310610a8f91 336 PANTHER PTHR24220 14 330 6.6E-153 T 23-04-2016 DC74_RS25825 165bbf019f2535351cd4f310610a8f91 336 Pfam PF00005 ABC transporter 33 191 3.4E-25 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS25825 165bbf019f2535351cd4f310610a8f91 336 SMART SM00382 41 241 9.2E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS25825 165bbf019f2535351cd4f310610a8f91 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 327 3.0E-27 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS25825 165bbf019f2535351cd4f310610a8f91 336 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS25825 165bbf019f2535351cd4f310610a8f91 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 307 1.9E-20 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS25825 165bbf019f2535351cd4f310610a8f91 336 SUPERFAMILY SSF52540 42 313 4.42E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25825 165bbf019f2535351cd4f310610a8f91 336 PANTHER PTHR24220:SF535 14 330 6.6E-153 T 23-04-2016 DC74_RS25825 165bbf019f2535351cd4f310610a8f91 336 Gene3D G3DSA:3.40.50.300 11 265 1.2E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26255 bb2f364c101f8425b1228729fb00fab5 159 PANTHER PTHR23404 17 157 5.8E-33 T 23-04-2016 DC74_RS26255 bb2f364c101f8425b1228729fb00fab5 159 Gene3D G3DSA:3.90.1170.40 25 158 9.9E-46 T 23-04-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS26255 bb2f364c101f8425b1228729fb00fab5 159 SUPERFAMILY SSF54690 27 158 8.11E-40 T 23-04-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS26255 bb2f364c101f8425b1228729fb00fab5 159 Pfam PF02391 MoaE protein 30 140 3.5E-34 T 23-04-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS26255 bb2f364c101f8425b1228729fb00fab5 159 PANTHER PTHR23404:SF2 17 157 5.8E-33 T 23-04-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS27230 c8b7f96b1faf958e4e7c42bafb717370 386 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 198 359 1.6E-31 T 23-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS27230 c8b7f96b1faf958e4e7c42bafb717370 386 Gene3D G3DSA:3.40.50.2000 3 195 7.1E-50 T 23-04-2016 DC74_RS27230 c8b7f96b1faf958e4e7c42bafb717370 386 Gene3D G3DSA:3.40.50.2000 196 354 5.9E-23 T 23-04-2016 DC74_RS27230 c8b7f96b1faf958e4e7c42bafb717370 386 PANTHER PTHR21015:SF22 2 352 4.4E-90 T 23-04-2016 DC74_RS27230 c8b7f96b1faf958e4e7c42bafb717370 386 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 7 372 30.706 T 23-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS27230 c8b7f96b1faf958e4e7c42bafb717370 386 SUPERFAMILY SSF53756 7 372 3.93E-87 T 23-04-2016 DC74_RS27230 c8b7f96b1faf958e4e7c42bafb717370 386 PANTHER PTHR21015 2 352 4.4E-90 T 23-04-2016 DC74_RS27230 c8b7f96b1faf958e4e7c42bafb717370 386 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 7 141 1.6E-29 T 23-04-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 Gene3D G3DSA:1.10.150.280 874 921 5.9E-4 T 23-04-2016 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 SMART SM00481 6 74 1.8E-28 T 23-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 Gene3D G3DSA:3.20.20.140 5 78 5.7E-37 T 23-04-2016 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 Gene3D G3DSA:3.20.20.140 115 287 5.7E-37 T 23-04-2016 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 Pfam PF02811 PHP domain 7 203 2.1E-41 T 23-04-2016 IPR004013 PHP domain GO:0003824 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1074 0.0 T 23-04-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 325 775 8.9E-146 T 23-04-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 PANTHER PTHR32294:SF0 105 1172 0.0 T 23-04-2016 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 PANTHER PTHR32294:SF0 2 86 0.0 T 23-04-2016 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 SUPERFAMILY SSF89550 131 292 1.16E-24 T 23-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 SUPERFAMILY SSF89550 5 88 1.16E-24 T 23-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 PANTHER PTHR32294 105 1172 0.0 T 23-04-2016 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 PANTHER PTHR32294 2 86 0.0 T 23-04-2016 DC74_RS08525 606c17c84e9ffdaed5921279e25875e9 1198 Pfam PF14579 Helix-hairpin-helix motif 848 935 2.6E-27 T 23-04-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS27530 e295502b0ada5a2db6f9719bdd3b1998 389 Gene3D G3DSA:3.90.1150.10 251 376 3.8E-38 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS27530 e295502b0ada5a2db6f9719bdd3b1998 389 SUPERFAMILY SSF53383 1 381 1.99E-93 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS27530 e295502b0ada5a2db6f9719bdd3b1998 389 Pfam PF00266 Aminotransferase class-V 2 372 6.4E-64 T 23-04-2016 IPR000192 Aminotransferase class V domain DC74_RS27530 e295502b0ada5a2db6f9719bdd3b1998 389 Gene3D G3DSA:3.40.640.10 15 250 6.4E-73 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS27530 e295502b0ada5a2db6f9719bdd3b1998 389 PANTHER PTHR11601 1 384 3.6E-139 T 23-04-2016 DC74_RS27530 e295502b0ada5a2db6f9719bdd3b1998 389 PIRSF PIRSF005572 1 386 8.4E-111 T 23-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 DC74_RS27530 e295502b0ada5a2db6f9719bdd3b1998 389 PANTHER PTHR11601:SF20 1 384 3.6E-139 T 23-04-2016 DC74_RS28685 bfe46d38c7ff57487014b325b008b83a 127 SMART SM00530 11 66 1.4E-9 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS28685 bfe46d38c7ff57487014b325b008b83a 127 Pfam PF13560 Helix-turn-helix domain 8 65 9.0E-11 T 23-04-2016 DC74_RS28685 bfe46d38c7ff57487014b325b008b83a 127 Gene3D G3DSA:1.10.260.40 8 73 6.9E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS28685 bfe46d38c7ff57487014b325b008b83a 127 SUPERFAMILY SSF47413 3 72 1.55E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS06355 e0b7881dc6bb56fd50e7c38466433cb5 507 SUPERFAMILY SSF51445 18 256 1.64E-21 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS06355 e0b7881dc6bb56fd50e7c38466433cb5 507 SUPERFAMILY SSF51445 286 318 1.64E-21 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS06355 e0b7881dc6bb56fd50e7c38466433cb5 507 PANTHER PTHR11177:SF203 65 313 9.3E-39 T 23-04-2016 DC74_RS06355 e0b7881dc6bb56fd50e7c38466433cb5 507 SMART SM00495 459 504 9.5E-17 T 23-04-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 DC74_RS06355 e0b7881dc6bb56fd50e7c38466433cb5 507 Pfam PF00704 Glycosyl hydrolases family 18 43 235 2.6E-15 T 23-04-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 DC74_RS06355 e0b7881dc6bb56fd50e7c38466433cb5 507 Gene3D G3DSA:2.10.10.20 456 507 3.0E-19 T 23-04-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 DC74_RS06355 e0b7881dc6bb56fd50e7c38466433cb5 507 Pfam PF02839 Carbohydrate binding domain 460 501 6.7E-12 T 23-04-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 DC74_RS06355 e0b7881dc6bb56fd50e7c38466433cb5 507 SUPERFAMILY SSF51055 456 507 2.35E-15 T 23-04-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 DC74_RS06355 e0b7881dc6bb56fd50e7c38466433cb5 507 Gene3D G3DSA:3.20.20.80 41 314 1.9E-12 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS06355 e0b7881dc6bb56fd50e7c38466433cb5 507 PANTHER PTHR11177 65 313 9.3E-39 T 23-04-2016 DC74_RS33625 79bf3c023a3255d3c116c4ce961c71c6 70 Pfam PF13499 EF-hand domain pair 6 65 2.2E-10 T 23-04-2016 IPR002048 EF-hand domain GO:0005509 DC74_RS33625 79bf3c023a3255d3c116c4ce961c71c6 70 ProSitePatterns PS00018 EF-hand calcium-binding domain. 52 64 - T 23-04-2016 IPR018247 EF-Hand 1, calcium-binding site DC74_RS33625 79bf3c023a3255d3c116c4ce961c71c6 70 SMART SM00054 43 68 40.0 T 23-04-2016 IPR002048 EF-hand domain GO:0005509 DC74_RS33625 79bf3c023a3255d3c116c4ce961c71c6 70 SMART SM00054 6 34 9.1E-6 T 23-04-2016 IPR002048 EF-hand domain GO:0005509 DC74_RS33625 79bf3c023a3255d3c116c4ce961c71c6 70 ProSitePatterns PS00018 EF-hand calcium-binding domain. 15 27 - T 23-04-2016 IPR018247 EF-Hand 1, calcium-binding site DC74_RS33625 79bf3c023a3255d3c116c4ce961c71c6 70 SUPERFAMILY SSF47473 4 66 9.03E-17 T 23-04-2016 IPR011992 EF-hand domain pair DC74_RS33625 79bf3c023a3255d3c116c4ce961c71c6 70 Gene3D G3DSA:1.10.238.10 4 68 3.5E-17 T 23-04-2016 IPR011992 EF-hand domain pair DC74_RS37585 cabc5f5b52078dd26b73fda6f45217e0 248 Pfam PF14016 Protein of unknown function (DUF4232) 117 244 2.1E-21 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS25600 f241d00017e7083dba1015bd73b4b52d 558 ProSitePatterns PS00163 Fumarate lyases signature. 460 469 - T 23-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 DC74_RS25600 f241d00017e7083dba1015bd73b4b52d 558 Pfam PF05681 Fumarate hydratase (Fumerase) 47 324 3.5E-89 T 23-04-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 DC74_RS25600 f241d00017e7083dba1015bd73b4b52d 558 Gene3D G3DSA:3.20.130.10 361 540 1.2E-73 T 23-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 DC74_RS25600 f241d00017e7083dba1015bd73b4b52d 558 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 377 540 7.5E-58 T 23-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 DC74_RS25600 f241d00017e7083dba1015bd73b4b52d 558 PANTHER PTHR30389:SF0 1 541 0.0 T 23-04-2016 DC74_RS25600 f241d00017e7083dba1015bd73b4b52d 558 PIRSF PIRSF001394 28 556 3.8E-224 T 23-04-2016 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 DC74_RS25600 f241d00017e7083dba1015bd73b4b52d 558 SUPERFAMILY SSF117457 365 540 2.22E-61 T 23-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 DC74_RS25600 f241d00017e7083dba1015bd73b4b52d 558 PANTHER PTHR30389 1 541 0.0 T 23-04-2016 DC74_RS25600 f241d00017e7083dba1015bd73b4b52d 558 Pfam PF05683 Fumarase C-terminus 330 541 3.4E-91 T 23-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 DC74_RS25600 f241d00017e7083dba1015bd73b4b52d 558 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 51 325 2.7E-32 T 23-04-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 DC74_RS02980 2ddd2f263d11627aa4cb66158d418101 128 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.1E-24 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS02980 2ddd2f263d11627aa4cb66158d418101 128 SUPERFAMILY SSF46785 3 83 7.02E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02980 2ddd2f263d11627aa4cb66158d418101 128 Gene3D G3DSA:1.10.10.10 2 83 9.4E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02980 2ddd2f263d11627aa4cb66158d418101 128 PANTHER PTHR30346 1 126 3.4E-43 T 23-04-2016 DC74_RS02980 2ddd2f263d11627aa4cb66158d418101 128 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 7.6E-12 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS02980 2ddd2f263d11627aa4cb66158d418101 128 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 7.6E-12 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS02980 2ddd2f263d11627aa4cb66158d418101 128 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 7.6E-12 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS02980 2ddd2f263d11627aa4cb66158d418101 128 PANTHER PTHR30346:SF7 1 126 3.4E-43 T 23-04-2016 DC74_RS21715 5763c69bd871b37557e89bd07633ea63 165 SUPERFAMILY SSF46785 27 152 2.86E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21715 5763c69bd871b37557e89bd07633ea63 165 PANTHER PTHR33164 29 161 4.1E-21 T 23-04-2016 DC74_RS21715 5763c69bd871b37557e89bd07633ea63 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 2.7E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21715 5763c69bd871b37557e89bd07633ea63 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 2.7E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21715 5763c69bd871b37557e89bd07633ea63 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 2.7E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21715 5763c69bd871b37557e89bd07633ea63 165 Pfam PF12802 MarR family 44 100 4.4E-11 T 23-04-2016 DC74_RS21715 5763c69bd871b37557e89bd07633ea63 165 SMART SM00347 33 136 2.2E-18 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS21715 5763c69bd871b37557e89bd07633ea63 165 Gene3D G3DSA:1.10.10.10 5 153 1.5E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31315 32f6ef52914eb3324fdc90ce18ee7cac 388 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 163 1.5E-42 T 23-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DC74_RS31315 32f6ef52914eb3324fdc90ce18ee7cac 388 PANTHER PTHR18968:SF14 1 163 9.2E-43 T 23-04-2016 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47|UniPathway: UPA00864 DC74_RS31315 32f6ef52914eb3324fdc90ce18ee7cac 388 Gene3D G3DSA:3.40.50.970 2 165 4.2E-46 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS31315 32f6ef52914eb3324fdc90ce18ee7cac 388 SUPERFAMILY SSF52518 201 368 1.64E-19 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS31315 32f6ef52914eb3324fdc90ce18ee7cac 388 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 253 310 1.2E-5 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS31315 32f6ef52914eb3324fdc90ce18ee7cac 388 SUPERFAMILY SSF52518 2 171 3.44E-40 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS31315 32f6ef52914eb3324fdc90ce18ee7cac 388 Gene3D G3DSA:3.40.50.970 208 370 5.6E-17 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS31315 32f6ef52914eb3324fdc90ce18ee7cac 388 PANTHER PTHR18968 1 163 9.2E-43 T 23-04-2016 DC74_RS25230 e454cbac7bc1e068228c0474acb0fbf2 166 SUPERFAMILY SSF46785 34 152 6.58E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25230 e454cbac7bc1e068228c0474acb0fbf2 166 Pfam PF01047 MarR family 48 103 5.2E-14 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS25230 e454cbac7bc1e068228c0474acb0fbf2 166 PANTHER PTHR33164:SF2 45 162 4.9E-22 T 23-04-2016 DC74_RS25230 e454cbac7bc1e068228c0474acb0fbf2 166 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 111 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS25230 e454cbac7bc1e068228c0474acb0fbf2 166 SMART SM00347 30 138 6.9E-16 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS25230 e454cbac7bc1e068228c0474acb0fbf2 166 PANTHER PTHR33164 45 162 4.9E-22 T 23-04-2016 DC74_RS25230 e454cbac7bc1e068228c0474acb0fbf2 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 2.0E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS25230 e454cbac7bc1e068228c0474acb0fbf2 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 2.0E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS25230 e454cbac7bc1e068228c0474acb0fbf2 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 2.0E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS25230 e454cbac7bc1e068228c0474acb0fbf2 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 2.0E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS25230 e454cbac7bc1e068228c0474acb0fbf2 166 Gene3D G3DSA:1.10.10.10 10 152 3.6E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16585 647db2366b1dcac147b5b41e5bc2255f 393 Gene3D G3DSA:1.20.1250.20 2 182 4.1E-27 T 23-04-2016 DC74_RS16585 647db2366b1dcac147b5b41e5bc2255f 393 PANTHER PTHR23501:SF4 4 382 6.0E-66 T 23-04-2016 DC74_RS16585 647db2366b1dcac147b5b41e5bc2255f 393 PANTHER PTHR23501 4 382 6.0E-66 T 23-04-2016 DC74_RS16585 647db2366b1dcac147b5b41e5bc2255f 393 Gene3D G3DSA:1.20.1250.20 198 379 1.5E-7 T 23-04-2016 DC74_RS16585 647db2366b1dcac147b5b41e5bc2255f 393 Pfam PF07690 Major Facilitator Superfamily 8 308 4.0E-31 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS16585 647db2366b1dcac147b5b41e5bc2255f 393 SUPERFAMILY SSF103473 3 381 4.05E-48 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS37830 1de42698ba9a1d794a4272cff4f65a18 247 SUPERFAMILY SSF53335 10 244 2.39E-28 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS37830 1de42698ba9a1d794a4272cff4f65a18 247 Gene3D G3DSA:3.40.50.150 7 223 1.1E-25 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS37830 1de42698ba9a1d794a4272cff4f65a18 247 Pfam PF13649 Methyltransferase domain 46 138 2.0E-10 T 23-04-2016 DC74_RS22045 4d8d854bc0c511eb6fae87e194038b25 281 Gene3D G3DSA:3.30.460.10 53 87 1.3E-5 T 23-04-2016 DC74_RS22045 4d8d854bc0c511eb6fae87e194038b25 281 SUPERFAMILY SSF81301 46 80 8.18E-6 T 23-04-2016 DC74_RS33040 55ab751f212ad632c849914bde81a852 480 ProSitePatterns PS00218 Amino acid permeases signature. 56 86 - T 23-04-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 DC74_RS33040 55ab751f212ad632c849914bde81a852 480 PIRSF PIRSF006060 11 479 1.3E-61 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS33040 55ab751f212ad632c849914bde81a852 480 PANTHER PTHR11785:SF25 14 477 1.9E-262 T 23-04-2016 DC74_RS33040 55ab751f212ad632c849914bde81a852 480 Pfam PF00324 Amino acid permease 31 469 4.4E-104 T 23-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 DC74_RS33040 55ab751f212ad632c849914bde81a852 480 PANTHER PTHR11785 14 477 1.9E-262 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS31080 345f203ee3e94f514dbba7c54d6d98d2 327 PANTHER PTHR11562:SF55 7 317 1.1E-122 T 23-04-2016 DC74_RS31080 345f203ee3e94f514dbba7c54d6d98d2 327 Gene3D G3DSA:3.30.70.1350 228 306 2.9E-15 T 23-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain DC74_RS31080 345f203ee3e94f514dbba7c54d6d98d2 327 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 32 308 6.4E-66 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DC74_RS31080 345f203ee3e94f514dbba7c54d6d98d2 327 Pfam PF01545 Cation efflux family 34 227 3.2E-38 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DC74_RS31080 345f203ee3e94f514dbba7c54d6d98d2 327 Gene3D G3DSA:1.20.1510.10 32 227 7.3E-39 T 23-04-2016 IPR027469 Cation efflux protein transmembrane domain DC74_RS31080 345f203ee3e94f514dbba7c54d6d98d2 327 SUPERFAMILY SSF161111 29 228 1.96E-46 T 23-04-2016 DC74_RS31080 345f203ee3e94f514dbba7c54d6d98d2 327 Pfam PF16916 Dimerisation domain of Zinc Transporter 235 306 1.1E-12 T 23-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain DC74_RS31080 345f203ee3e94f514dbba7c54d6d98d2 327 SUPERFAMILY SSF160240 229 306 5.75E-14 T 23-04-2016 DC74_RS31080 345f203ee3e94f514dbba7c54d6d98d2 327 PANTHER PTHR11562 7 317 1.1E-122 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DC74_RS40300 4e975477f8988231540b986b25a7d5cf 148 PANTHER PTHR26402 18 95 1.4E-15 T 23-04-2016 DC74_RS40300 4e975477f8988231540b986b25a7d5cf 148 PANTHER PTHR26402:SF316 18 95 1.4E-15 T 23-04-2016 DC74_RS40300 4e975477f8988231540b986b25a7d5cf 148 SMART SM00448 18 125 9.2E-4 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS40300 4e975477f8988231540b986b25a7d5cf 148 SUPERFAMILY SSF52172 10 130 1.99E-16 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS40300 4e975477f8988231540b986b25a7d5cf 148 Pfam PF00072 Response regulator receiver domain 20 108 1.3E-8 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS40300 4e975477f8988231540b986b25a7d5cf 148 Gene3D G3DSA:3.40.50.2300 16 111 7.7E-14 T 23-04-2016 DC74_RS03575 575cf77ad7d0b4916e9c909b0e6e1a97 212 PANTHER PTHR30055:SF54 2 177 1.6E-42 T 23-04-2016 DC74_RS03575 575cf77ad7d0b4916e9c909b0e6e1a97 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 60 1.6E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03575 575cf77ad7d0b4916e9c909b0e6e1a97 212 PANTHER PTHR30055 2 177 1.6E-42 T 23-04-2016 DC74_RS03575 575cf77ad7d0b4916e9c909b0e6e1a97 212 Gene3D G3DSA:1.10.357.10 58 200 2.6E-19 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS03575 575cf77ad7d0b4916e9c909b0e6e1a97 212 SUPERFAMILY SSF46689 5 75 1.2E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03575 575cf77ad7d0b4916e9c909b0e6e1a97 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 7.5E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03575 575cf77ad7d0b4916e9c909b0e6e1a97 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 7.5E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03575 575cf77ad7d0b4916e9c909b0e6e1a97 212 Gene3D G3DSA:1.10.10.60 6 57 8.6E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS16685 5ebe465e27e8ae2edbb4874780a0a0b4 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 5.3E-86 T 23-04-2016 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 DC74_RS16685 5ebe465e27e8ae2edbb4874780a0a0b4 229 PANTHER PTHR24220:SF470 3 223 2.1E-120 T 23-04-2016 DC74_RS16685 5ebe465e27e8ae2edbb4874780a0a0b4 229 Pfam PF00005 ABC transporter 19 166 8.0E-34 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS16685 5ebe465e27e8ae2edbb4874780a0a0b4 229 SUPERFAMILY SSF52540 1 221 3.59E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16685 5ebe465e27e8ae2edbb4874780a0a0b4 229 Gene3D G3DSA:3.40.50.300 1 221 1.5E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16685 5ebe465e27e8ae2edbb4874780a0a0b4 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS16685 5ebe465e27e8ae2edbb4874780a0a0b4 229 PANTHER PTHR24220 3 223 2.1E-120 T 23-04-2016 DC74_RS16685 5ebe465e27e8ae2edbb4874780a0a0b4 229 SMART SM00382 28 215 1.5E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 SUPERFAMILY SSF51735 9 189 1.21E-51 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 SUPERFAMILY SSF48179 189 298 1.79E-27 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 SUPERFAMILY SSF48179 420 502 1.96E-14 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 Gene3D G3DSA:3.40.50.720 9 191 5.1E-55 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 188 2.5E-57 T 23-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 PANTHER PTHR23309:SF12 408 503 9.4E-206 T 23-04-2016 DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 PANTHER PTHR23309:SF12 9 306 9.4E-206 T 23-04-2016 DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 Gene3D G3DSA:1.10.1040.10 192 287 3.4E-26 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 Gene3D G3DSA:1.10.1040.10 421 496 4.9E-16 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 PANTHER PTHR23309 408 503 9.4E-206 T 23-04-2016 DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 PANTHER PTHR23309 9 306 9.4E-206 T 23-04-2016 DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 421 502 4.9E-14 T 23-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS20440 34b0d69974a336c9c68cc5dcaf7bc935 508 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 287 1.5E-26 T 23-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS36765 5094cee1d17cba4811e0989e5879793e 353 PANTHER PTHR33744 74 352 1.9E-52 T 23-04-2016 DC74_RS36765 5094cee1d17cba4811e0989e5879793e 353 Pfam PF13556 PucR C-terminal helix-turn-helix domain 284 340 2.1E-15 T 23-04-2016 IPR025736 PucR C-terminal helix-turn-helix domain DC74_RS36765 5094cee1d17cba4811e0989e5879793e 353 PANTHER PTHR33744:SF4 74 352 1.9E-52 T 23-04-2016 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 Pfam PF00668 Condensation domain 18 310 1.2E-32 T 23-04-2016 IPR001242 Condensation domain DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 SMART SM00823 Phosphopantetheine attachment site 997 1065 6.6E-8 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 499 912 4.2E-119 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 Gene3D G3DSA:3.30.300.30 884 1001 4.0E-37 T 23-04-2016 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 Pfam PF13193 AMP-binding enzyme C-terminal domain 896 972 3.5E-15 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 Gene3D G3DSA:2.30.38.10 800 877 7.9E-26 T 23-04-2016 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 Gene3D G3DSA:3.40.50.980 471 584 7.2E-45 T 23-04-2016 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 Gene3D G3DSA:3.40.50.980 625 661 7.2E-45 T 23-04-2016 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 SMART SM01294 998 1061 0.0023 T 23-04-2016 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 SUPERFAMILY SSF52777 20 194 1.22E-27 T 23-04-2016 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 Gene3D G3DSA:3.40.50.980 662 799 4.9E-33 T 23-04-2016 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 SUPERFAMILY SSF56801 445 1009 7.2E-144 T 23-04-2016 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 Pfam PF00550 Phosphopantetheine attachment site 999 1060 1.5E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 ProSitePatterns PS00455 Putative AMP-binding domain signature. 640 651 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 SUPERFAMILY SSF47336 990 1060 7.2E-18 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 PANTHER PTHR24095:SF137 18 1060 1.8E-257 T 23-04-2016 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 SUPERFAMILY SSF52777 200 438 3.45E-44 T 23-04-2016 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 Gene3D G3DSA:1.10.1200.10 1002 1063 1.2E-24 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1021 1036 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 Pfam PF00501 AMP-binding enzyme 477 888 7.6E-87 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS29450 a2c3fef5927e35661fe5ae4ff7b45d6a 1089 PANTHER PTHR24095 18 1060 1.8E-257 T 23-04-2016 DC74_RS39970 832dce6897f5bf4ceb08e076b210c390 292 SUPERFAMILY SSF53041 86 231 6.02E-24 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS39970 832dce6897f5bf4ceb08e076b210c390 292 Gene3D G3DSA:3.40.50.1390 87 215 1.3E-21 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS39970 832dce6897f5bf4ceb08e076b210c390 292 Pfam PF00239 Resolvase, N terminal domain 87 231 3.1E-27 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS39970 832dce6897f5bf4ceb08e076b210c390 292 SMART SM00857 86 231 3.3E-27 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS39970 832dce6897f5bf4ceb08e076b210c390 292 Gene3D G3DSA:1.10.10.60 233 263 3.8E-4 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39970 832dce6897f5bf4ceb08e076b210c390 292 PANTHER PTHR30461 87 266 1.2E-25 T 23-04-2016 DC74_RS40500 ecb31919e5685635202a54e59c6b5ea7 390 PANTHER PTHR11712 1 185 6.3E-12 T 23-04-2016 DC74_RS40500 ecb31919e5685635202a54e59c6b5ea7 390 Gene3D G3DSA:3.40.366.10 99 187 3.9E-11 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 DC74_RS40500 ecb31919e5685635202a54e59c6b5ea7 390 SUPERFAMILY SSF52151 99 190 3.92E-12 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 DC74_RS40500 ecb31919e5685635202a54e59c6b5ea7 390 PANTHER PTHR11712:SF288 1 185 6.3E-12 T 23-04-2016 DC74_RS16715 6aa66ef2cd38c8ae1c6efdcaafe0b097 1260 PANTHER PTHR23308 104 192 2.6E-13 T 23-04-2016 DC74_RS16715 6aa66ef2cd38c8ae1c6efdcaafe0b097 1260 SUPERFAMILY SSF49879 91 197 1.38E-24 T 23-04-2016 IPR008984 SMAD/FHA domain GO:0005515 DC74_RS16715 6aa66ef2cd38c8ae1c6efdcaafe0b097 1260 Pfam PF01580 FtsK/SpoIIIE family 786 907 6.1E-16 T 23-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 DC74_RS16715 6aa66ef2cd38c8ae1c6efdcaafe0b097 1260 Gene3D G3DSA:3.40.50.300 782 872 6.5E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16715 6aa66ef2cd38c8ae1c6efdcaafe0b097 1260 Gene3D G3DSA:2.60.200.20 99 197 2.6E-23 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS16715 6aa66ef2cd38c8ae1c6efdcaafe0b097 1260 SUPERFAMILY SSF52540 802 902 2.92E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16715 6aa66ef2cd38c8ae1c6efdcaafe0b097 1260 SMART SM00240 123 174 4.8E-11 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS16715 6aa66ef2cd38c8ae1c6efdcaafe0b097 1260 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 106 198 7.1E-16 T 23-04-2016 IPR032030 YscD, cytoplasmic domain DC74_RS06930 c84f9b54e73f8827dad053000be3d031 549 PANTHER PTHR11785:SF322 17 433 5.5E-112 T 23-04-2016 DC74_RS06930 c84f9b54e73f8827dad053000be3d031 549 Pfam PF13520 Amino acid permease 21 429 1.2E-44 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS06930 c84f9b54e73f8827dad053000be3d031 549 PANTHER PTHR11785 17 433 5.5E-112 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS07540 ce33e3505197938474921a5796b94996 235 PANTHER PTHR24220 15 217 7.5E-70 T 23-04-2016 DC74_RS07540 ce33e3505197938474921a5796b94996 235 SMART SM00382 38 226 9.3E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS07540 ce33e3505197938474921a5796b94996 235 Pfam PF00005 ABC transporter 30 176 5.4E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS07540 ce33e3505197938474921a5796b94996 235 SUPERFAMILY SSF52540 13 228 1.13E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07540 ce33e3505197938474921a5796b94996 235 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS07540 ce33e3505197938474921a5796b94996 235 Gene3D G3DSA:3.40.50.300 13 229 9.2E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17640 4d8ae723a5e079e59cad4ea21f052392 292 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 6 272 1.1E-60 T 23-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS17640 4d8ae723a5e079e59cad4ea21f052392 292 PIRSF PIRSF005917 1 280 3.9E-89 T 23-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS17640 4d8ae723a5e079e59cad4ea21f052392 292 PANTHER PTHR21091:SF18 2 230 3.2E-66 T 23-04-2016 DC74_RS17640 4d8ae723a5e079e59cad4ea21f052392 292 PANTHER PTHR21091 2 230 3.2E-66 T 23-04-2016 DC74_RS17640 4d8ae723a5e079e59cad4ea21f052392 292 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 207 8.5E-31 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS17640 4d8ae723a5e079e59cad4ea21f052392 292 Gene3D G3DSA:3.40.1010.10 3 113 5.6E-7 T 23-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 DC74_RS17640 4d8ae723a5e079e59cad4ea21f052392 292 Gene3D G3DSA:3.30.950.10 114 225 3.9E-44 T 23-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 DC74_RS17640 4d8ae723a5e079e59cad4ea21f052392 292 SUPERFAMILY SSF53790 3 222 2.36E-72 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS17640 4d8ae723a5e079e59cad4ea21f052392 292 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 4 224 32.752 T 23-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 DC74_RS10755 846a4617024810a7cf4ecc7cd7c9f4d1 268 Gene3D G3DSA:3.40.50.1110 36 257 1.8E-66 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS10755 846a4617024810a7cf4ecc7cd7c9f4d1 268 PANTHER PTHR37981:SF3 1 263 5.2E-88 T 23-04-2016 DC74_RS10755 846a4617024810a7cf4ecc7cd7c9f4d1 268 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 40 257 8.7E-26 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS10755 846a4617024810a7cf4ecc7cd7c9f4d1 268 PANTHER PTHR37981 1 263 5.2E-88 T 23-04-2016 DC74_RS10755 846a4617024810a7cf4ecc7cd7c9f4d1 268 SUPERFAMILY SSF52266 36 257 1.57E-59 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PANTHER PTHR24286:SF42 14 405 1.7E-94 T 23-04-2016 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 Gene3D G3DSA:1.10.630.10 12 405 1.1E-103 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 SUPERFAMILY SSF48264 21 405 3.14E-84 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PRINTS PR00359 B-class P450 signature 89 100 2.6E-28 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PRINTS PR00359 B-class P450 signature 295 322 2.6E-28 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PRINTS PR00359 B-class P450 signature 276 287 2.6E-28 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PRINTS PR00359 B-class P450 signature 155 170 2.6E-28 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PRINTS PR00359 B-class P450 signature 192 214 2.6E-28 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PRINTS PR00359 B-class P450 signature 354 365 2.6E-28 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PRINTS PR00359 B-class P450 signature 138 154 2.6E-28 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PRINTS PR00359 B-class P450 signature 345 354 2.6E-28 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PANTHER PTHR24286 14 405 1.7E-94 T 23-04-2016 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 Pfam PF00067 Cytochrome P450 277 375 2.2E-15 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PRINTS PR00385 P450 superfamily signature 354 365 5.2E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PRINTS PR00385 P450 superfamily signature 241 258 5.2E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PRINTS PR00385 P450 superfamily signature 276 287 5.2E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 PRINTS PR00385 P450 superfamily signature 345 354 5.2E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06350 4abf507cba701cbcd550cc9d71c8d677 411 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 347 356 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS34510 3b268634e803983c98f7ae210223defd 171 Gene3D G3DSA:2.70.50.50 119 170 1.2E-12 T 23-04-2016 DC74_RS34510 3b268634e803983c98f7ae210223defd 171 Gene3D G3DSA:2.70.50.50 31 114 2.0E-20 T 23-04-2016 DC74_RS34510 3b268634e803983c98f7ae210223defd 171 PANTHER PTHR34823 1 170 4.4E-66 T 23-04-2016 DC74_RS34510 3b268634e803983c98f7ae210223defd 171 SUPERFAMILY SSF81296 31 171 1.82E-35 T 23-04-2016 IPR014756 Immunoglobulin E-set DC74_RS34510 3b268634e803983c98f7ae210223defd 171 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 168 1.1E-16 T 23-04-2016 IPR004302 Chitin-binding protein, N-terminal DC74_RS34510 3b268634e803983c98f7ae210223defd 171 PANTHER PTHR34823:SF1 1 170 4.4E-66 T 23-04-2016 DC74_RS17030 04b8602727ba6a90ed90a33ad73cb99e 592 PANTHER PTHR33392:SF7 110 577 4.4E-143 T 23-04-2016 DC74_RS17030 04b8602727ba6a90ed90a33ad73cb99e 592 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 472 562 1.3E-10 T 23-04-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain DC74_RS17030 04b8602727ba6a90ed90a33ad73cb99e 592 PANTHER PTHR33392 110 577 4.4E-143 T 23-04-2016 DC74_RS17030 04b8602727ba6a90ed90a33ad73cb99e 592 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 201 363 9.8E-39 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS17030 04b8602727ba6a90ed90a33ad73cb99e 592 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 201 363 1.4E-42 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS19880 172c26a199c66b5b5f2d43910c64a3c2 340 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 9 337 1.5E-70 T 23-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 DC74_RS19880 172c26a199c66b5b5f2d43910c64a3c2 340 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 23-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 DC74_RS19880 172c26a199c66b5b5f2d43910c64a3c2 340 SUPERFAMILY SSF51569 4 336 2.64E-95 T 23-04-2016 DC74_RS19880 172c26a199c66b5b5f2d43910c64a3c2 340 Gene3D G3DSA:3.20.20.70 2 337 9.8E-116 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS19880 172c26a199c66b5b5f2d43910c64a3c2 340 PIRSF PIRSF001359 5 338 8.4E-63 T 23-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 DC74_RS19880 172c26a199c66b5b5f2d43910c64a3c2 340 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 336 2.0E-79 T 23-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 DC74_RS19880 172c26a199c66b5b5f2d43910c64a3c2 340 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 337 1.2E-128 T 23-04-2016 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|UniPathway: UPA00109 DC74_RS19880 172c26a199c66b5b5f2d43910c64a3c2 340 PANTHER PTHR30559 1 339 2.5E-207 T 23-04-2016 DC74_RS19880 172c26a199c66b5b5f2d43910c64a3c2 340 PANTHER PTHR30559:SF0 1 339 2.5E-207 T 23-04-2016 DC74_RS00185 695d8bc415f1ed99239c1768888b4de3 1385 Gene3D G3DSA:3.40.1140.10 1279 1345 3.6E-21 T 23-04-2016 DC74_RS00185 695d8bc415f1ed99239c1768888b4de3 1385 Gene3D G3DSA:3.40.1140.10 29 119 3.6E-21 T 23-04-2016 DC74_RS00185 695d8bc415f1ed99239c1768888b4de3 1385 TIGRFAM TIGR02680 TIGR02680: TIGR02680 family protein 30 1382 0.0 T 23-04-2016 IPR013496 Conserved hypothetical protein CHP02680 DC74_RS00185 695d8bc415f1ed99239c1768888b4de3 1385 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1247 1333 9.5E-19 T 23-04-2016 DC74_RS00185 695d8bc415f1ed99239c1768888b4de3 1385 SUPERFAMILY SSF52540 44 205 3.1E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00185 695d8bc415f1ed99239c1768888b4de3 1385 SUPERFAMILY SSF52540 1267 1343 3.1E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00185 695d8bc415f1ed99239c1768888b4de3 1385 SUPERFAMILY SSF52540 253 284 3.1E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15480 6ace5d9ffb95617a19d7c58ce912fbcb 366 SUPERFAMILY SSF82861 93 155 3.92E-11 T 23-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 DC74_RS15480 6ace5d9ffb95617a19d7c58ce912fbcb 366 Gene3D G3DSA:2.30.30.60 172 216 1.0E-9 T 23-04-2016 DC74_RS15480 6ace5d9ffb95617a19d7c58ce912fbcb 366 SUPERFAMILY SSF50182 157 214 7.52E-10 T 23-04-2016 IPR010920 LSM domain DC74_RS15480 6ace5d9ffb95617a19d7c58ce912fbcb 366 SUPERFAMILY SSF82689 221 315 6.41E-10 T 23-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 DC74_RS15480 6ace5d9ffb95617a19d7c58ce912fbcb 366 PANTHER PTHR30460 26 345 1.2E-91 T 23-04-2016 DC74_RS15480 6ace5d9ffb95617a19d7c58ce912fbcb 366 Gene3D G3DSA:3.30.70.100 227 312 1.6E-6 T 23-04-2016 DC74_RS15480 6ace5d9ffb95617a19d7c58ce912fbcb 366 Pfam PF00924 Mechanosensitive ion channel 115 313 1.7E-34 T 23-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 DC74_RS05465 8da6c8e79ce3905a4dd454e38a1d2ecc 651 Pfam PF07940 Heparinase II/III-like protein 403 637 1.5E-49 T 23-04-2016 IPR012480 Heparinase II/III-like MetaCyc: PWY-7651 DC74_RS05465 8da6c8e79ce3905a4dd454e38a1d2ecc 651 Gene3D G3DSA:1.50.10.110 94 338 2.5E-7 T 23-04-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 DC74_RS05465 8da6c8e79ce3905a4dd454e38a1d2ecc 651 Pfam PF16889 Heparinase II/III N-terminus 129 310 1.5E-14 T 23-04-2016 IPR031680 Heparin-sulfate lyase, N-terminal MetaCyc: PWY-7651 DC74_RS05465 8da6c8e79ce3905a4dd454e38a1d2ecc 651 SUPERFAMILY SSF48230 95 375 2.47E-29 T 23-04-2016 IPR008929 Chondroitin AC/alginate lyase DC74_RS05465 8da6c8e79ce3905a4dd454e38a1d2ecc 651 PANTHER PTHR39210 1 650 2.0E-139 T 23-04-2016 DC74_RS15370 a63b6b8fb2829e06d0cb44fd370e1208 273 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 93 1.7E-9 T 23-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 DC74_RS15370 a63b6b8fb2829e06d0cb44fd370e1208 273 SUPERFAMILY SSF57716 220 268 2.38E-12 T 23-04-2016 DC74_RS15370 a63b6b8fb2829e06d0cb44fd370e1208 273 SMART SM00898 2 108 5.4E-20 T 23-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 DC74_RS15370 a63b6b8fb2829e06d0cb44fd370e1208 273 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 205 1.7E-21 T 23-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 DC74_RS15370 a63b6b8fb2829e06d0cb44fd370e1208 273 SMART SM01232 122 214 1.9E-34 T 23-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 DC74_RS15370 a63b6b8fb2829e06d0cb44fd370e1208 273 ProSitePatterns PS01242 Zinc finger FPG-type signature. 243 267 - T 23-04-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 DC74_RS15370 a63b6b8fb2829e06d0cb44fd370e1208 273 SUPERFAMILY SSF46946 121 205 1.28E-25 T 23-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 DC74_RS15370 a63b6b8fb2829e06d0cb44fd370e1208 273 PANTHER PTHR22993 1 268 5.2E-57 T 23-04-2016 DC74_RS15370 a63b6b8fb2829e06d0cb44fd370e1208 273 SUPERFAMILY SSF81624 2 123 4.19E-24 T 23-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 DC74_RS15370 a63b6b8fb2829e06d0cb44fd370e1208 273 Pfam PF06827 Zinc finger found in FPG and IleRS 242 268 1.7E-4 T 23-04-2016 IPR010663 Zinc finger, FPG/IleRS-type DC74_RS15370 a63b6b8fb2829e06d0cb44fd370e1208 273 Gene3D G3DSA:1.10.8.50 123 268 3.5E-44 T 23-04-2016 DC74_RS15370 a63b6b8fb2829e06d0cb44fd370e1208 273 Gene3D G3DSA:3.20.190.10 2 122 1.6E-15 T 23-04-2016 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 Pfam PF00083 Sugar (and other) transporter 14 446 6.0E-114 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 ProSitePatterns PS00216 Sugar transport proteins signature 1. 302 319 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 Gene3D G3DSA:1.20.1250.20 252 445 1.5E-22 T 23-04-2016 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 Gene3D G3DSA:1.20.1250.20 11 189 1.0E-23 T 23-04-2016 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 PANTHER PTHR23500 9 445 1.0E-167 T 23-04-2016 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 ProSitePatterns PS00217 Sugar transport proteins signature 2. 106 131 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 5 443 4.2E-115 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 SUPERFAMILY SSF103473 8 444 5.1E-74 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 81 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 PRINTS PR00171 Sugar transporter signature 348 369 1.8E-27 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 PRINTS PR00171 Sugar transporter signature 101 120 1.8E-27 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 PRINTS PR00171 Sugar transporter signature 18 28 1.8E-27 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 PRINTS PR00171 Sugar transporter signature 371 383 1.8E-27 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS11875 b6be83c6c3faaebf0cc8210efda7b018 471 PRINTS PR00171 Sugar transporter signature 258 268 1.8E-27 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 PANTHER PTHR11908 1 119 9.6E-142 T 23-04-2016 DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 PANTHER PTHR11908 162 327 9.6E-142 T 23-04-2016 DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 219 3.0E-49 T 23-04-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 Gene3D G3DSA:3.30.43.10 1 51 1.4E-18 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 Gene3D G3DSA:3.30.390.50 225 328 2.4E-30 T 23-04-2016 DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 PANTHER PTHR11908:SF97 1 119 9.6E-142 T 23-04-2016 DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 PANTHER PTHR11908:SF97 162 327 9.6E-142 T 23-04-2016 DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 227 323 1.5E-18 T 23-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 Gene3D G3DSA:3.30.465.10 157 219 8.3E-33 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 Gene3D G3DSA:3.30.465.10 56 113 8.3E-33 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 SUPERFAMILY SSF56176 1 219 9.81E-58 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 SMART SM01092 226 324 3.4E-29 T 23-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal DC74_RS03920 eba2e5d39cf582ee6adc79fada267365 336 SUPERFAMILY SSF55447 226 327 1.96E-24 T 23-04-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal DC74_RS14040 6309fbc012af8b689e100d57fd0390f0 82 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 17.194 T 23-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 DC74_RS14040 6309fbc012af8b689e100d57fd0390f0 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 80 3.0E-17 T 23-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 DC74_RS14040 6309fbc012af8b689e100d57fd0390f0 82 Pfam PF00550 Phosphopantetheine attachment site 12 77 3.5E-16 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS14040 6309fbc012af8b689e100d57fd0390f0 82 SUPERFAMILY SSF47336 2 81 7.07E-22 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS14040 6309fbc012af8b689e100d57fd0390f0 82 Gene3D G3DSA:1.10.1200.10 3 81 9.4E-25 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS14040 6309fbc012af8b689e100d57fd0390f0 82 PANTHER PTHR20863:SF28 1 80 3.2E-16 T 23-04-2016 DC74_RS14040 6309fbc012af8b689e100d57fd0390f0 82 PANTHER PTHR20863 1 80 3.2E-16 T 23-04-2016 DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 SUPERFAMILY SSF52518 396 606 3.93E-67 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 220 355 7.1E-47 T 23-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 Gene3D G3DSA:3.40.50.970 29 206 3.0E-70 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 456 475 - T 23-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 SUPERFAMILY SSF52467 212 387 7.12E-62 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 31 604 5.8E-229 T 23-04-2016 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 PANTHER PTHR18968:SF116 6 606 0.0 T 23-04-2016 DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 31 196 2.8E-55 T 23-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 SUPERFAMILY SSF52518 29 209 3.91E-59 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 Gene3D G3DSA:3.40.50.970 380 596 3.9E-76 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 Gene3D G3DSA:3.40.50.1220 215 379 1.0E-66 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 PANTHER PTHR18968 6 606 0.0 T 23-04-2016 DC74_RS27685 06d2b4ca839c14d65728607b7164bb81 618 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 419 580 2.0E-47 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS10105 7be155ce0142cdd48b69010ee5c9b645 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.819 T 23-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 DC74_RS10105 7be155ce0142cdd48b69010ee5c9b645 64 SUPERFAMILY SSF143034 2 63 4.19E-21 T 23-04-2016 DC74_RS10105 7be155ce0142cdd48b69010ee5c9b645 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 23-04-2016 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS10105 7be155ce0142cdd48b69010ee5c9b645 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 6.0E-17 T 23-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 DC74_RS10105 7be155ce0142cdd48b69010ee5c9b645 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 6.0E-17 T 23-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 DC74_RS10105 7be155ce0142cdd48b69010ee5c9b645 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 6.0E-17 T 23-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 DC74_RS10105 7be155ce0142cdd48b69010ee5c9b645 64 PANTHER PTHR33343 1 62 2.0E-23 T 23-04-2016 DC74_RS10105 7be155ce0142cdd48b69010ee5c9b645 64 Pfam PF01632 Ribosomal protein L35 2 62 3.6E-24 T 23-04-2016 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS10105 7be155ce0142cdd48b69010ee5c9b645 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 6.8E-26 T 23-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 DC74_RS00135 7e3feb8ec79d79031cc36863a168518c 244 SUPERFAMILY SSF140453 24 104 3.53E-5 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS00135 7e3feb8ec79d79031cc36863a168518c 244 Pfam PF06013 Proteins of 100 residues with WXG 23 100 5.3E-7 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS21610 a09778a0a4a81170c52811051093718c 707 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 340 706 2.7E-79 T 23-04-2016 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component DC74_RS21610 a09778a0a4a81170c52811051093718c 707 PANTHER PTHR37809 82 707 3.6E-47 T 23-04-2016 DC74_RS21610 a09778a0a4a81170c52811051093718c 707 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 343 663 5.4E-23 T 23-04-2016 IPR003776 YcaO-like domain DC74_RS21610 a09778a0a4a81170c52811051093718c 707 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 342 663 3.0E-69 T 23-04-2016 IPR003776 YcaO-like domain DC74_RS05730 80fecc3df651ff518010ad0f3f9dc823 337 SUPERFAMILY SSF51197 28 314 3.66E-71 T 23-04-2016 DC74_RS05730 80fecc3df651ff518010ad0f3f9dc823 337 PANTHER PTHR10696:SF27 31 314 3.6E-64 T 23-04-2016 DC74_RS05730 80fecc3df651ff518010ad0f3f9dc823 337 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 33 312 1.3E-45 T 23-04-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 DC74_RS05730 80fecc3df651ff518010ad0f3f9dc823 337 Gene3D G3DSA:3.60.130.10 195 317 3.9E-61 T 23-04-2016 DC74_RS05730 80fecc3df651ff518010ad0f3f9dc823 337 Gene3D G3DSA:3.60.130.10 24 163 3.9E-61 T 23-04-2016 DC74_RS05730 80fecc3df651ff518010ad0f3f9dc823 337 PANTHER PTHR10696 31 314 3.6E-64 T 23-04-2016 DC74_RS23260 154e40bede62cf9c54b30180e6da43e0 291 PANTHER PTHR35010:SF2 5 290 3.6E-86 T 23-04-2016 DC74_RS23260 154e40bede62cf9c54b30180e6da43e0 291 Pfam PF13560 Helix-turn-helix domain 8 85 7.7E-17 T 23-04-2016 DC74_RS23260 154e40bede62cf9c54b30180e6da43e0 291 SMART SM00530 11 84 7.6E-10 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS23260 154e40bede62cf9c54b30180e6da43e0 291 Gene3D G3DSA:1.10.260.40 32 84 3.7E-19 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS23260 154e40bede62cf9c54b30180e6da43e0 291 SUPERFAMILY SSF47413 32 85 6.52E-10 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS23260 154e40bede62cf9c54b30180e6da43e0 291 PANTHER PTHR35010 5 290 3.6E-86 T 23-04-2016 DC74_RS10190 5efa2fc43232916b74cb25c212f4b013 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 30 86 2.3E-19 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS10190 5efa2fc43232916b74cb25c212f4b013 319 PANTHER PTHR30126:SF11 26 299 2.2E-82 T 23-04-2016 DC74_RS10190 5efa2fc43232916b74cb25c212f4b013 319 Gene3D G3DSA:1.10.10.10 27 108 3.0E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10190 5efa2fc43232916b74cb25c212f4b013 319 SUPERFAMILY SSF53850 110 313 1.09E-36 T 23-04-2016 DC74_RS10190 5efa2fc43232916b74cb25c212f4b013 319 SUPERFAMILY SSF46785 24 135 2.85E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10190 5efa2fc43232916b74cb25c212f4b013 319 Gene3D G3DSA:3.40.190.10 202 287 9.3E-19 T 23-04-2016 DC74_RS10190 5efa2fc43232916b74cb25c212f4b013 319 PANTHER PTHR30126 26 299 2.2E-82 T 23-04-2016 DC74_RS10190 5efa2fc43232916b74cb25c212f4b013 319 Gene3D G3DSA:3.40.190.10 117 201 2.5E-16 T 23-04-2016 DC74_RS10190 5efa2fc43232916b74cb25c212f4b013 319 Pfam PF03466 LysR substrate binding domain 113 314 1.6E-41 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS10190 5efa2fc43232916b74cb25c212f4b013 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 64 1.82E-5 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS10190 5efa2fc43232916b74cb25c212f4b013 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.82E-5 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS10190 5efa2fc43232916b74cb25c212f4b013 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 64 75 1.82E-5 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS34525 a730e9d7f8719f6427ad2eea71a590cb 308 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 41 288 1.1E-68 T 23-04-2016 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 DC74_RS34525 a730e9d7f8719f6427ad2eea71a590cb 308 SUPERFAMILY SSF56112 51 290 3.21E-27 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS27140 4342c8c63cf801c1f98ba1934a9aa313 312 PANTHER PTHR23242:SF11 1 309 2.1E-81 T 23-04-2016 DC74_RS27140 4342c8c63cf801c1f98ba1934a9aa313 312 PANTHER PTHR23242 1 309 2.1E-81 T 23-04-2016 DC74_RS22575 cb65133bf73ba64857d077f54c38f218 265 SUPERFAMILY SSF53067 1 127 9.5E-34 T 23-04-2016 DC74_RS22575 cb65133bf73ba64857d077f54c38f218 265 Gene3D G3DSA:3.30.420.40 99 262 2.9E-50 T 23-04-2016 DC74_RS22575 cb65133bf73ba64857d077f54c38f218 265 SUPERFAMILY SSF53067 129 261 1.68E-36 T 23-04-2016 DC74_RS22575 cb65133bf73ba64857d077f54c38f218 265 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 262 36.131 T 23-04-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 DC74_RS22575 cb65133bf73ba64857d077f54c38f218 265 Pfam PF03309 Type III pantothenate kinase 2 211 6.3E-70 T 23-04-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 DC74_RS22575 cb65133bf73ba64857d077f54c38f218 265 Gene3D G3DSA:3.30.420.40 1 68 1.2E-4 T 23-04-2016 DC74_RS22575 cb65133bf73ba64857d077f54c38f218 265 PANTHER PTHR34265 1 265 2.6E-79 T 23-04-2016 DC74_RS22575 cb65133bf73ba64857d077f54c38f218 265 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 258 1.5E-76 T 23-04-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 DC74_RS07440 763010320576b4aba3de03f43c9c85fb 132 SUPERFAMILY SSF55620 2 129 3.22E-27 T 23-04-2016 DC74_RS07440 763010320576b4aba3de03f43c9c85fb 132 PANTHER PTHR12589:SF4 2 130 1.7E-59 T 23-04-2016 DC74_RS07440 763010320576b4aba3de03f43c9c85fb 132 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 130 6.7E-21 T 23-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein DC74_RS07440 763010320576b4aba3de03f43c9c85fb 132 Gene3D G3DSA:3.30.479.10 2 130 1.0E-40 T 23-04-2016 DC74_RS07440 763010320576b4aba3de03f43c9c85fb 132 PANTHER PTHR12589 2 130 1.7E-59 T 23-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein DC74_RS01175 3298c749993e609f0fad50ceeb02217d 242 PANTHER PTHR10245 7 214 1.3E-25 T 23-04-2016 DC74_RS01175 3298c749993e609f0fad50ceeb02217d 242 SUPERFAMILY SSF50475 100 223 1.75E-19 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS01175 3298c749993e609f0fad50ceeb02217d 242 SMART SM00530 23 78 4.0E-10 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS01175 3298c749993e609f0fad50ceeb02217d 242 Gene3D G3DSA:2.30.110.10 95 225 3.0E-34 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS01175 3298c749993e609f0fad50ceeb02217d 242 Gene3D G3DSA:1.10.260.40 20 84 5.8E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS01175 3298c749993e609f0fad50ceeb02217d 242 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 104 222 6.4E-19 T 23-04-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related DC74_RS01175 3298c749993e609f0fad50ceeb02217d 242 SUPERFAMILY SSF47413 19 82 2.62E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS01175 3298c749993e609f0fad50ceeb02217d 242 PANTHER PTHR10245:SF54 7 214 1.3E-25 T 23-04-2016 DC74_RS01175 3298c749993e609f0fad50ceeb02217d 242 Pfam PF13560 Helix-turn-helix domain 19 78 5.7E-10 T 23-04-2016 DC74_RS24670 f6a75974b1c7c31ce810e04aa45af5f8 292 Gene3D G3DSA:1.10.260.40 9 68 2.8E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS24670 f6a75974b1c7c31ce810e04aa45af5f8 292 SMART SM00530 17 72 4.6E-4 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS24670 f6a75974b1c7c31ce810e04aa45af5f8 292 PANTHER PTHR10245:SF29 7 282 3.5E-40 T 23-04-2016 DC74_RS24670 f6a75974b1c7c31ce810e04aa45af5f8 292 SUPERFAMILY SSF47413 11 68 1.21E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS24670 f6a75974b1c7c31ce810e04aa45af5f8 292 Pfam PF13560 Helix-turn-helix domain 13 76 8.6E-13 T 23-04-2016 DC74_RS24670 f6a75974b1c7c31ce810e04aa45af5f8 292 PANTHER PTHR10245 7 282 3.5E-40 T 23-04-2016 DC74_RS02365 4adf46536e0d36fff3ea2fb3916ba675 246 PANTHER PTHR20842:SF2 5 235 3.6E-109 T 23-04-2016 DC74_RS02365 4adf46536e0d36fff3ea2fb3916ba675 246 PANTHER PTHR20842 5 235 3.6E-109 T 23-04-2016 DC74_RS02365 4adf46536e0d36fff3ea2fb3916ba675 246 Pfam PF03575 Peptidase family S51 6 206 1.7E-56 T 23-04-2016 IPR005320 Peptidase S51 GO:0006508|GO:0008236 DC74_RS02365 4adf46536e0d36fff3ea2fb3916ba675 246 Gene3D G3DSA:3.40.50.880 5 230 4.5E-74 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS02365 4adf46536e0d36fff3ea2fb3916ba675 246 SUPERFAMILY SSF52317 6 212 1.42E-36 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS22615 17d76d313580528cee51c994e7fc93b8 229 Gene3D G3DSA:2.70.70.10 68 223 2.3E-43 T 23-04-2016 DC74_RS22615 17d76d313580528cee51c994e7fc93b8 229 PANTHER PTHR21666 59 224 9.1E-37 T 23-04-2016 DC74_RS22615 17d76d313580528cee51c994e7fc93b8 229 SUPERFAMILY SSF51261 65 210 5.23E-43 T 23-04-2016 IPR011055 Duplicated hybrid motif DC74_RS22615 17d76d313580528cee51c994e7fc93b8 229 Pfam PF01551 Peptidase family M23 116 208 1.6E-31 T 23-04-2016 IPR016047 Peptidase M23 DC74_RS26235 e8b6a43164dc41bb079e32ea1d3ba92d 439 Pfam PF02342 TerD domain 1 170 2.7E-30 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS26235 e8b6a43164dc41bb079e32ea1d3ba92d 439 Gene3D G3DSA:2.60.60.30 31 167 1.4E-21 T 23-04-2016 DC74_RS26235 e8b6a43164dc41bb079e32ea1d3ba92d 439 PANTHER PTHR32097:SF3 206 264 3.9E-87 T 23-04-2016 DC74_RS26235 e8b6a43164dc41bb079e32ea1d3ba92d 439 PANTHER PTHR32097:SF3 1 190 3.9E-87 T 23-04-2016 DC74_RS26235 e8b6a43164dc41bb079e32ea1d3ba92d 439 PANTHER PTHR32097 206 264 3.9E-87 T 23-04-2016 DC74_RS26235 e8b6a43164dc41bb079e32ea1d3ba92d 439 PANTHER PTHR32097 1 190 3.9E-87 T 23-04-2016 DC74_RS21705 d7902e7459b4a26897102cd9707f547f 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 62 6.1E-15 T 23-04-2016 DC74_RS21705 d7902e7459b4a26897102cd9707f547f 64 Gene3D G3DSA:3.30.70.20 1 64 3.4E-18 T 23-04-2016 DC74_RS21705 d7902e7459b4a26897102cd9707f547f 64 SUPERFAMILY SSF54862 2 63 3.98E-15 T 23-04-2016 DC74_RS21705 d7902e7459b4a26897102cd9707f547f 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 2.8E-8 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS21705 d7902e7459b4a26897102cd9707f547f 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 2.8E-8 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS21705 d7902e7459b4a26897102cd9707f547f 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 2.8E-8 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS21705 d7902e7459b4a26897102cd9707f547f 64 PANTHER PTHR36923:SF1 1 62 9.7E-22 T 23-04-2016 DC74_RS21705 d7902e7459b4a26897102cd9707f547f 64 PANTHER PTHR36923 1 62 9.7E-22 T 23-04-2016 DC74_RS35660 443771d79815e7b62d68092b7a4624f0 137 Pfam PF00720 Subtilisin inhibitor-like 42 123 8.9E-24 T 23-04-2016 IPR023549 Subtilisin inhibitor GO:0004867 DC74_RS35660 443771d79815e7b62d68092b7a4624f0 137 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 112 128 1.7E-10 T 23-04-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 DC74_RS35660 443771d79815e7b62d68092b7a4624f0 137 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 61 88 1.7E-10 T 23-04-2016 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 DC74_RS35660 443771d79815e7b62d68092b7a4624f0 137 SUPERFAMILY SSF55399 46 137 3.14E-24 T 23-04-2016 IPR023549 Subtilisin inhibitor GO:0004867 DC74_RS35660 443771d79815e7b62d68092b7a4624f0 137 Gene3D G3DSA:3.30.350.10 38 137 1.4E-33 T 23-04-2016 IPR023549 Subtilisin inhibitor GO:0004867 DC74_RS35660 443771d79815e7b62d68092b7a4624f0 137 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 54 125 8.0E-13 T 23-04-2016 IPR023549 Subtilisin inhibitor GO:0004867 DC74_RS39050 1e837c19b17f98e2ad88cb6d4a40386f 366 PANTHER PTHR11746:SF63 13 129 4.6E-48 T 23-04-2016 DC74_RS39050 1e837c19b17f98e2ad88cb6d4a40386f 366 PANTHER PTHR11746:SF63 156 352 4.6E-48 T 23-04-2016 DC74_RS39050 1e837c19b17f98e2ad88cb6d4a40386f 366 Gene3D G3DSA:1.10.10.10 14 91 2.9E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39050 1e837c19b17f98e2ad88cb6d4a40386f 366 Pfam PF16864 Dimerisation domain 18 95 1.9E-16 T 23-04-2016 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain DC74_RS39050 1e837c19b17f98e2ad88cb6d4a40386f 366 SUPERFAMILY SSF53335 159 362 1.59E-37 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS39050 1e837c19b17f98e2ad88cb6d4a40386f 366 Gene3D G3DSA:3.40.50.150 114 362 3.8E-45 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS39050 1e837c19b17f98e2ad88cb6d4a40386f 366 SUPERFAMILY SSF46785 17 92 2.58E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39050 1e837c19b17f98e2ad88cb6d4a40386f 366 Pfam PF00891 O-methyltransferase 156 352 1.4E-32 T 23-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 DC74_RS39050 1e837c19b17f98e2ad88cb6d4a40386f 366 PANTHER PTHR11746 13 129 4.6E-48 T 23-04-2016 DC74_RS39050 1e837c19b17f98e2ad88cb6d4a40386f 366 PANTHER PTHR11746 156 352 4.6E-48 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PIRSF PIRSF000350 1 460 9.1E-85 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 9.8E-65 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 9.8E-65 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 9.8E-65 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 9.8E-65 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 9.8E-65 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 9.8E-65 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 9.8E-65 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 9.8E-65 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 9.8E-65 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 SUPERFAMILY SSF55424 343 465 6.36E-38 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PANTHER PTHR22912:SF125 1 459 1.9E-189 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 2.8E-36 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.8E-36 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 2.8E-36 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 2.8E-36 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 2.8E-36 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 23-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 Gene3D G3DSA:3.50.50.60 142 332 4.4E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 466 8.0E-162 T 23-04-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 Gene3D G3DSA:3.50.50.60 3 141 5.7E-37 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 SUPERFAMILY SSF51905 2 336 4.29E-64 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 PANTHER PTHR22912 1 459 1.9E-189 T 23-04-2016 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 327 2.3E-66 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 Gene3D G3DSA:3.30.390.30 333 464 3.6E-43 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS04330 80e27d2e57929c947d0a46ab95959b8e 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 5.8E-34 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS20135 58b8b7fdaa6bc19c23bf558566d76086 245 Pfam PF13349 Putative adhesin 122 236 5.4E-9 T 23-04-2016 IPR025164 Putative adhesin DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 PANTHER PTHR22683 1361 1452 3.0E-186 T 23-04-2016 DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 Gene3D G3DSA:3.40.50.300 957 1144 1.4E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 Gene3D G3DSA:3.40.50.300 305 376 1.1E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 Gene3D G3DSA:3.40.50.300 1227 1294 1.7E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 Gene3D G3DSA:3.40.50.300 609 825 2.3E-22 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 SUPERFAMILY SSF52540 601 822 7.83E-30 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 SUPERFAMILY SSF52540 942 1165 5.56E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 PANTHER PTHR22683 581 862 3.0E-186 T 23-04-2016 DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 PANTHER PTHR22683 1027 1311 3.0E-186 T 23-04-2016 DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 SUPERFAMILY SSF52540 1199 1386 3.25E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 PANTHER PTHR22683:SF1 1361 1452 3.0E-186 T 23-04-2016 DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 Pfam PF00656 Caspase domain 4 232 3.6E-9 T 23-04-2016 DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 ProSitePatterns PS00018 EF-hand calcium-binding domain. 201 213 - T 23-04-2016 IPR018247 EF-Hand 1, calcium-binding site DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 882 1452 1.3E-226 T 23-04-2016 IPR023837 EccCb-like, Actinobacteria DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 SUPERFAMILY SSF52129 4 216 1.41E-12 T 23-04-2016 IPR029030 Caspase-like domain DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 PANTHER PTHR22683:SF1 581 862 3.0E-186 T 23-04-2016 DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 PANTHER PTHR22683:SF1 1027 1311 3.0E-186 T 23-04-2016 DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 SMART SM00382 321 500 0.49 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 SMART SM00382 637 816 1.3 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 SMART SM00382 963 1135 4.3 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 SMART SM00382 1248 1451 0.43 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 Pfam PF01580 FtsK/SpoIIIE family 607 728 1.2E-24 T 23-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 Pfam PF01580 FtsK/SpoIIIE family 312 515 3.9E-35 T 23-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 Pfam PF01580 FtsK/SpoIIIE family 945 1176 9.0E-50 T 23-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 Gene3D G3DSA:3.40.50.1460 2 134 9.5E-4 T 23-04-2016 IPR029030 Caspase-like domain DC74_RS40260 ee5d278184789148494d1b7458f777dd 1457 SUPERFAMILY SSF52540 299 502 3.61E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS03460 6203990e5d43a4088284150ab88530ad 331 PANTHER PTHR11746:SF63 1 317 6.6E-53 T 23-04-2016 DC74_RS03460 6203990e5d43a4088284150ab88530ad 331 Pfam PF16864 Dimerisation domain 1 82 3.1E-13 T 23-04-2016 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain DC74_RS03460 6203990e5d43a4088284150ab88530ad 331 Gene3D G3DSA:3.40.50.150 81 318 7.0E-57 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS03460 6203990e5d43a4088284150ab88530ad 331 Pfam PF00891 O-methyltransferase 91 314 1.8E-43 T 23-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 DC74_RS03460 6203990e5d43a4088284150ab88530ad 331 Gene3D G3DSA:1.10.10.10 1 74 5.8E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03460 6203990e5d43a4088284150ab88530ad 331 PANTHER PTHR11746 1 317 6.6E-53 T 23-04-2016 DC74_RS03460 6203990e5d43a4088284150ab88530ad 331 SUPERFAMILY SSF53335 81 318 4.52E-47 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS03460 6203990e5d43a4088284150ab88530ad 331 SUPERFAMILY SSF46785 1 74 1.43E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02825 85de7425df04c8a5cd38d8d6d2a32f43 171 PANTHER PTHR42305 1 171 5.8E-19 T 23-04-2016 DC74_RS38320 b175a1a9bf794a5a7a2f2e0c75ef2057 251 PANTHER PTHR17630 9 251 1.1E-83 T 23-04-2016 DC74_RS38320 b175a1a9bf794a5a7a2f2e0c75ef2057 251 SUPERFAMILY SSF53474 10 251 1.04E-41 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS38320 b175a1a9bf794a5a7a2f2e0c75ef2057 251 Gene3D G3DSA:3.40.50.1820 5 249 1.9E-50 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS38320 b175a1a9bf794a5a7a2f2e0c75ef2057 251 Pfam PF01738 Dienelactone hydrolase family 19 250 8.2E-43 T 23-04-2016 IPR002925 Dienelactone hydrolase GO:0016787 DC74_RS38320 b175a1a9bf794a5a7a2f2e0c75ef2057 251 PANTHER PTHR17630:SF51 9 251 1.1E-83 T 23-04-2016 DC74_RS17760 9764fe89698134ad1c490d2b1185a70f 66 Pfam PF04149 Domain of unknown function (DUF397) 7 62 1.9E-19 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS02000 63cda87261a26109e9d781f3689da08e 397 SUPERFAMILY SSF53756 26 303 2.2E-6 T 23-04-2016 DC74_RS02000 63cda87261a26109e9d781f3689da08e 397 Gene3D G3DSA:3.40.50.2000 162 304 1.8E-5 T 23-04-2016 DC74_RS06180 9a0d8a39383dc77513f5fab1821d1be6 346 SUPERFAMILY SSF51735 18 339 7.81E-75 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06180 9a0d8a39383dc77513f5fab1821d1be6 346 Gene3D G3DSA:3.30.1780.10 19 147 1.4E-32 T 23-04-2016 IPR023401 Ornithine cyclodeaminase, N-terminal DC74_RS06180 9a0d8a39383dc77513f5fab1821d1be6 346 PIRSF PIRSF001439 13 338 5.8E-62 T 23-04-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin DC74_RS06180 9a0d8a39383dc77513f5fab1821d1be6 346 Gene3D G3DSA:3.40.50.720 148 312 2.6E-42 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06180 9a0d8a39383dc77513f5fab1821d1be6 346 PANTHER PTHR13812 18 342 4.4E-57 T 23-04-2016 DC74_RS06180 9a0d8a39383dc77513f5fab1821d1be6 346 PANTHER PTHR13812:SF19 18 342 4.4E-57 T 23-04-2016 DC74_RS06180 9a0d8a39383dc77513f5fab1821d1be6 346 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 21 330 2.6E-62 T 23-04-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin DC74_RS30985 2d69a66481a9126ca978183abfaedebb 380 PANTHER PTHR30582 17 378 1.6E-58 T 23-04-2016 DC74_RS30985 2d69a66481a9126ca978183abfaedebb 380 Gene3D G3DSA:2.40.440.10 228 348 1.0E-16 T 23-04-2016 DC74_RS30985 2d69a66481a9126ca978183abfaedebb 380 PANTHER PTHR30582:SF2 17 378 1.6E-58 T 23-04-2016 DC74_RS30985 2d69a66481a9126ca978183abfaedebb 380 SUPERFAMILY SSF141523 228 348 1.96E-21 T 23-04-2016 DC74_RS30985 2d69a66481a9126ca978183abfaedebb 380 Pfam PF03734 L,D-transpeptidase catalytic domain 232 348 4.4E-13 T 23-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 DC74_RS35190 4299805ce4dc21bc40ad96fe85f7df61 801 SUPERFAMILY SSF48208 274 777 9.35E-97 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 DC74_RS35190 4299805ce4dc21bc40ad96fe85f7df61 801 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 735 788 5.4E-6 T 23-04-2016 IPR005194 Glycoside hydrolase family 65, C-terminal DC74_RS35190 4299805ce4dc21bc40ad96fe85f7df61 801 Gene3D G3DSA:1.50.10.10 316 717 1.1E-127 T 23-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 DC74_RS35190 4299805ce4dc21bc40ad96fe85f7df61 801 PANTHER PTHR11051:SF9 6 796 0.0 T 23-04-2016 DC74_RS35190 4299805ce4dc21bc40ad96fe85f7df61 801 SUPERFAMILY SSF74650 4 268 1.6E-57 T 23-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 DC74_RS35190 4299805ce4dc21bc40ad96fe85f7df61 801 Gene3D G3DSA:2.70.98.40 4 269 7.1E-76 T 23-04-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 DC74_RS35190 4299805ce4dc21bc40ad96fe85f7df61 801 PANTHER PTHR11051 6 796 0.0 T 23-04-2016 DC74_RS35190 4299805ce4dc21bc40ad96fe85f7df61 801 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 9 267 9.5E-61 T 23-04-2016 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 DC74_RS35190 4299805ce4dc21bc40ad96fe85f7df61 801 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 319 730 1.2E-147 T 23-04-2016 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 DC74_RS35190 4299805ce4dc21bc40ad96fe85f7df61 801 PIRSF PIRSF036289 1 795 1.4E-199 T 23-04-2016 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase DC74_RS39170 24002c284b8017ff47924675e281c23a 446 SUPERFAMILY SSF103473 17 411 6.1E-24 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS39170 24002c284b8017ff47924675e281c23a 446 PANTHER PTHR23513 1 437 1.9E-37 T 23-04-2016 DC74_RS39170 24002c284b8017ff47924675e281c23a 446 Pfam PF07690 Major Facilitator Superfamily 60 313 3.1E-11 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS39170 24002c284b8017ff47924675e281c23a 446 Gene3D G3DSA:1.20.1250.20 17 207 7.3E-10 T 23-04-2016 DC74_RS39170 24002c284b8017ff47924675e281c23a 446 Gene3D G3DSA:1.20.1250.20 237 410 3.6E-5 T 23-04-2016 DC74_RS33060 87e2bd4bedaaa265783402c2b2827132 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 232 239 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS33060 87e2bd4bedaaa265783402c2b2827132 490 Gene3D G3DSA:3.40.309.10 248 435 6.3E-50 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS33060 87e2bd4bedaaa265783402c2b2827132 490 SUPERFAMILY SSF53720 6 460 2.23E-123 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS33060 87e2bd4bedaaa265783402c2b2827132 490 Pfam PF00171 Aldehyde dehydrogenase family 6 453 1.7E-117 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS33060 87e2bd4bedaaa265783402c2b2827132 490 PANTHER PTHR11699 6 466 3.5E-147 T 23-04-2016 DC74_RS33060 87e2bd4bedaaa265783402c2b2827132 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 260 271 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS33060 87e2bd4bedaaa265783402c2b2827132 490 Gene3D G3DSA:3.40.605.10 6 247 1.4E-66 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS32385 c4d9cf452d066ac557bdab560075e9bb 414 SUPERFAMILY SSF53756 102 413 2.16E-64 T 23-04-2016 DC74_RS32385 c4d9cf452d066ac557bdab560075e9bb 414 SUPERFAMILY SSF53756 1 67 2.16E-64 T 23-04-2016 DC74_RS32385 c4d9cf452d066ac557bdab560075e9bb 414 PANTHER PTHR11926:SF16 267 404 9.0E-13 T 23-04-2016 DC74_RS32385 c4d9cf452d066ac557bdab560075e9bb 414 Gene3D G3DSA:3.40.50.2000 1 223 2.0E-18 T 23-04-2016 DC74_RS32385 c4d9cf452d066ac557bdab560075e9bb 414 PANTHER PTHR11926 267 404 9.0E-13 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS32385 c4d9cf452d066ac557bdab560075e9bb 414 Gene3D G3DSA:3.40.50.2000 241 396 9.6E-29 T 23-04-2016 DC74_RS32385 c4d9cf452d066ac557bdab560075e9bb 414 Pfam PF06722 Protein of unknown function (DUF1205) 202 301 2.3E-10 T 23-04-2016 IPR010610 Domain of unknown function DUF1205 DC74_RS27425 f6d815f99b52af62c96b842f7b354cae 319 Pfam PF01435 Peptidase family M48 119 185 2.0E-9 T 23-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DC74_RS27425 f6d815f99b52af62c96b842f7b354cae 319 Gene3D G3DSA:3.30.2010.10 118 182 5.2E-14 T 23-04-2016 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PANTHER PTHR24286:SF42 42 391 6.6E-84 T 23-04-2016 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 Pfam PF00067 Cytochrome P450 264 359 8.3E-19 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 333 342 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 SUPERFAMILY SSF48264 20 391 1.83E-84 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PRINTS PR00385 P450 superfamily signature 264 275 2.9E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PRINTS PR00385 P450 superfamily signature 237 254 2.9E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PRINTS PR00385 P450 superfamily signature 331 340 2.9E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PRINTS PR00385 P450 superfamily signature 340 351 2.9E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PRINTS PR00359 B-class P450 signature 331 340 3.4E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PRINTS PR00359 B-class P450 signature 140 156 3.4E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PRINTS PR00359 B-class P450 signature 340 351 3.4E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PRINTS PR00359 B-class P450 signature 310 325 3.4E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PRINTS PR00359 B-class P450 signature 282 309 3.4E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PRINTS PR00359 B-class P450 signature 157 172 3.4E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PRINTS PR00359 B-class P450 signature 195 217 3.4E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PRINTS PR00359 B-class P450 signature 93 104 3.4E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 Gene3D G3DSA:1.10.630.10 6 391 4.0E-107 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06790 55454792603c692b08d86adc1e09a58a 391 PANTHER PTHR24286 42 391 6.6E-84 T 23-04-2016 DC74_RS04005 fad5431106ba44a7680d31f3200f867e 620 SUPERFAMILY SSF48208 220 619 8.85E-109 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 DC74_RS04005 fad5431106ba44a7680d31f3200f867e 620 Pfam PF00723 Glycosyl hydrolases family 15 247 612 3.1E-62 T 23-04-2016 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: REACT_474 DC74_RS04005 fad5431106ba44a7680d31f3200f867e 620 Gene3D G3DSA:1.50.10.10 241 619 4.2E-99 T 23-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 DC74_RS04005 fad5431106ba44a7680d31f3200f867e 620 PANTHER PTHR31616:SF0 1 619 3.1E-182 T 23-04-2016 DC74_RS04005 fad5431106ba44a7680d31f3200f867e 620 PANTHER PTHR31616 1 619 3.1E-182 T 23-04-2016 DC74_RS03940 a117cf4072825ce1cefdfa6f0972593b 328 SUPERFAMILY SSF56601 2 300 9.05E-65 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS03940 a117cf4072825ce1cefdfa6f0972593b 328 PANTHER PTHR22935 94 267 2.9E-53 T 23-04-2016 DC74_RS03940 a117cf4072825ce1cefdfa6f0972593b 328 PANTHER PTHR22935 1 78 2.9E-53 T 23-04-2016 DC74_RS03940 a117cf4072825ce1cefdfa6f0972593b 328 Gene3D G3DSA:3.40.710.10 2 307 6.0E-67 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS03940 a117cf4072825ce1cefdfa6f0972593b 328 PANTHER PTHR22935:SF69 94 267 2.9E-53 T 23-04-2016 DC74_RS03940 a117cf4072825ce1cefdfa6f0972593b 328 PANTHER PTHR22935:SF69 1 78 2.9E-53 T 23-04-2016 DC74_RS03940 a117cf4072825ce1cefdfa6f0972593b 328 Pfam PF00144 Beta-lactamase 2 301 2.6E-59 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 Pfam PF00067 Cytochrome P450 34 375 4.7E-27 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 Gene3D G3DSA:1.10.630.10 24 393 4.3E-107 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 PRINTS PR00359 B-class P450 signature 345 356 1.2E-46 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 PRINTS PR00359 B-class P450 signature 122 138 1.2E-46 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 PRINTS PR00359 B-class P450 signature 336 345 1.2E-46 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 PRINTS PR00359 B-class P450 signature 76 87 1.2E-46 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 PRINTS PR00359 B-class P450 signature 270 281 1.2E-46 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 PRINTS PR00359 B-class P450 signature 315 330 1.2E-46 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 PRINTS PR00359 B-class P450 signature 189 211 1.2E-46 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 PRINTS PR00359 B-class P450 signature 139 154 1.2E-46 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 PRINTS PR00359 B-class P450 signature 287 314 1.2E-46 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 338 347 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 PANTHER PTHR24286:SF42 35 391 3.1E-81 T 23-04-2016 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 PANTHER PTHR24286 35 391 3.1E-81 T 23-04-2016 DC74_RS32395 b99c7e7eacf559f2c137bef03e9584a3 395 SUPERFAMILY SSF48264 9 393 7.07E-87 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02505 1f8e279541b74187b2f17916f1572b5f 266 SUPERFAMILY SSF102588 5 238 4.71E-46 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS02505 1f8e279541b74187b2f17916f1572b5f 266 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 132 5.8E-19 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS02505 1f8e279541b74187b2f17916f1572b5f 266 Gene3D G3DSA:3.40.50.10320 5 242 6.5E-51 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS02505 1f8e279541b74187b2f17916f1572b5f 266 PANTHER PTHR12993 6 260 8.6E-35 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS02505 1f8e279541b74187b2f17916f1572b5f 266 PANTHER PTHR12993:SF13 6 260 8.6E-35 T 23-04-2016 DC74_RS09910 bbc8c9c7c51dc80706cf0e9df3ce420b 392 SUPERFAMILY SSF56266 7 388 5.75E-124 T 23-04-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS09910 bbc8c9c7c51dc80706cf0e9df3ce420b 392 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 18 390 8.0E-169 T 23-04-2016 DC74_RS09910 bbc8c9c7c51dc80706cf0e9df3ce420b 392 PANTHER PTHR23100:SF0 2 392 2.7E-151 T 23-04-2016 DC74_RS09910 bbc8c9c7c51dc80706cf0e9df3ce420b 392 Gene3D G3DSA:3.60.70.12 2 268 1.3E-91 T 23-04-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS09910 bbc8c9c7c51dc80706cf0e9df3ce420b 392 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 391 1.5E-102 T 23-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS09910 bbc8c9c7c51dc80706cf0e9df3ce420b 392 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 392 132.703 T 23-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS09910 bbc8c9c7c51dc80706cf0e9df3ce420b 392 Pfam PF01960 ArgJ family 11 392 3.5E-127 T 23-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS09910 bbc8c9c7c51dc80706cf0e9df3ce420b 392 PANTHER PTHR23100 2 392 2.7E-151 T 23-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS15815 b398069973af1f8c5f12df60475bce55 906 PANTHER PTHR11051:SF8 258 830 1.8E-165 T 23-04-2016 DC74_RS15815 b398069973af1f8c5f12df60475bce55 906 Gene3D G3DSA:2.60.420.10 696 758 5.2E-10 T 23-04-2016 DC74_RS15815 b398069973af1f8c5f12df60475bce55 906 Gene3D G3DSA:2.60.120.260 777 902 4.4E-14 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS15815 b398069973af1f8c5f12df60475bce55 906 Gene3D G3DSA:1.50.10.10 348 695 6.3E-111 T 23-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 DC74_RS15815 b398069973af1f8c5f12df60475bce55 906 SUPERFAMILY SSF48208 305 759 1.96E-91 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 DC74_RS15815 b398069973af1f8c5f12df60475bce55 906 Pfam PF00754 F5/8 type C domain 793 863 8.6E-12 T 23-04-2016 IPR000421 Coagulation factor 5/8 C-terminal domain DC74_RS15815 b398069973af1f8c5f12df60475bce55 906 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 363 582 8.4E-51 T 23-04-2016 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 DC74_RS15815 b398069973af1f8c5f12df60475bce55 906 SUPERFAMILY SSF49785 787 886 8.51E-17 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS15815 b398069973af1f8c5f12df60475bce55 906 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 714 759 2.3E-7 T 23-04-2016 IPR005194 Glycoside hydrolase family 65, C-terminal DC74_RS15815 b398069973af1f8c5f12df60475bce55 906 PANTHER PTHR11051 258 830 1.8E-165 T 23-04-2016 DC74_RS25695 fed158b66f4c734bf4175a14fe576705 76 Pfam PF13560 Helix-turn-helix domain 2 49 9.8E-10 T 23-04-2016 DC74_RS25695 fed158b66f4c734bf4175a14fe576705 76 Gene3D G3DSA:1.10.260.40 2 40 5.5E-6 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS25695 fed158b66f4c734bf4175a14fe576705 76 SUPERFAMILY SSF47413 2 41 9.6E-5 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS14275 ae301d467147d95dcddff0d5e28b92cd 496 SUPERFAMILY SSF53335 434 494 4.75E-43 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14275 ae301d467147d95dcddff0d5e28b92cd 496 SUPERFAMILY SSF53335 5 203 4.75E-43 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14275 ae301d467147d95dcddff0d5e28b92cd 496 SUPERFAMILY SSF53335 249 325 4.75E-43 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14275 ae301d467147d95dcddff0d5e28b92cd 496 Pfam PF00145 C-5 cytosine-specific DNA methylase 4 188 3.1E-10 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14275 ae301d467147d95dcddff0d5e28b92cd 496 Pfam PF00145 C-5 cytosine-specific DNA methylase 435 491 2.0E-7 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14275 ae301d467147d95dcddff0d5e28b92cd 496 Gene3D G3DSA:3.40.50.150 5 188 1.5E-22 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14275 ae301d467147d95dcddff0d5e28b92cd 496 Gene3D G3DSA:3.90.120.10 189 201 3.8E-11 T 23-04-2016 DC74_RS14275 ae301d467147d95dcddff0d5e28b92cd 496 Gene3D G3DSA:3.90.120.10 427 481 3.8E-11 T 23-04-2016 DC74_RS14275 ae301d467147d95dcddff0d5e28b92cd 496 Gene3D G3DSA:3.90.120.10 273 329 3.8E-11 T 23-04-2016 DC74_RS19765 f59bf5374aba5563b32c2c93ab64dbea 302 PANTHER PTHR30346 1 296 2.4E-50 T 23-04-2016 DC74_RS19765 f59bf5374aba5563b32c2c93ab64dbea 302 Gene3D G3DSA:3.40.190.10 96 182 3.4E-16 T 23-04-2016 DC74_RS19765 f59bf5374aba5563b32c2c93ab64dbea 302 Gene3D G3DSA:1.10.10.10 1 84 8.3E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19765 f59bf5374aba5563b32c2c93ab64dbea 302 SUPERFAMILY SSF46785 1 84 4.73E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19765 f59bf5374aba5563b32c2c93ab64dbea 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.4E-18 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS19765 f59bf5374aba5563b32c2c93ab64dbea 302 SUPERFAMILY SSF53850 95 296 7.72E-19 T 23-04-2016 DC74_RS19765 f59bf5374aba5563b32c2c93ab64dbea 302 Pfam PF03466 LysR substrate binding domain 94 288 1.7E-19 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS37310 50709ca8c6e90289c713db434329ee7e 136 SUPERFAMILY SSF55298 8 133 1.26E-33 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS37310 50709ca8c6e90289c713db434329ee7e 136 PANTHER PTHR11803:SF7 8 131 1.4E-35 T 23-04-2016 DC74_RS37310 50709ca8c6e90289c713db434329ee7e 136 Pfam PF01042 Endoribonuclease L-PSP 18 130 1.3E-25 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS37310 50709ca8c6e90289c713db434329ee7e 136 Gene3D G3DSA:3.30.1330.40 7 133 1.1E-39 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS37310 50709ca8c6e90289c713db434329ee7e 136 PANTHER PTHR11803 8 131 1.4E-35 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 Gene3D G3DSA:3.30.365.10 169 274 5.2E-34 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 PANTHER PTHR11908 564 780 0.0 T 23-04-2016 DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 PANTHER PTHR11908 7 545 0.0 T 23-04-2016 DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 27 133 1.9E-20 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 Gene3D G3DSA:3.90.1170.50 3 131 1.4E-33 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 SUPERFAMILY SSF54665 6 133 5.36E-33 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 Gene3D G3DSA:3.30.365.10 445 602 3.3E-53 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 155 702 6.8E-203 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 SMART SM01008 27 133 1.5E-34 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 SUPERFAMILY SSF56003 133 772 7.46E-197 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 Gene3D G3DSA:3.30.365.10 277 352 1.2E-30 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 Gene3D G3DSA:3.30.365.10 152 168 1.2E-30 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 PANTHER PTHR11908:SF66 564 780 0.0 T 23-04-2016 DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 PANTHER PTHR11908:SF66 7 545 0.0 T 23-04-2016 DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 13 771 5.0E-279 T 23-04-2016 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 Gene3D G3DSA:3.30.365.10 353 444 1.1E-72 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS02445 05d3db951f337fac07a2d0654da0089f 818 Gene3D G3DSA:3.30.365.10 612 774 1.1E-72 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS21850 31a10d5f8dd62542ec7d7ef767187e66 387 PIRSF PIRSF037226 1 387 1.5E-126 T 23-04-2016 IPR017144 Peptidase M20A, amidohydrolase, predicted DC74_RS21850 31a10d5f8dd62542ec7d7ef767187e66 387 PANTHER PTHR30575 1 371 3.1E-133 T 23-04-2016 DC74_RS21850 31a10d5f8dd62542ec7d7ef767187e66 387 Gene3D G3DSA:3.40.630.10 274 374 5.7E-64 T 23-04-2016 DC74_RS21850 31a10d5f8dd62542ec7d7ef767187e66 387 Gene3D G3DSA:3.40.630.10 3 164 5.7E-64 T 23-04-2016 DC74_RS21850 31a10d5f8dd62542ec7d7ef767187e66 387 Pfam PF01546 Peptidase family M20/M25/M40 84 338 5.6E-10 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS21850 31a10d5f8dd62542ec7d7ef767187e66 387 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 341 1.9E-60 T 23-04-2016 IPR017439 Amidohydrolase GO:0016787 DC74_RS21850 31a10d5f8dd62542ec7d7ef767187e66 387 SUPERFAMILY SSF55031 165 269 4.58E-22 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS21850 31a10d5f8dd62542ec7d7ef767187e66 387 PANTHER PTHR30575:SF0 1 371 3.1E-133 T 23-04-2016 DC74_RS21850 31a10d5f8dd62542ec7d7ef767187e66 387 Gene3D G3DSA:3.30.70.360 165 268 1.2E-24 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS21850 31a10d5f8dd62542ec7d7ef767187e66 387 Pfam PF07687 Peptidase dimerisation domain 164 257 9.4E-12 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS21850 31a10d5f8dd62542ec7d7ef767187e66 387 SUPERFAMILY SSF53187 277 370 2.32E-59 T 23-04-2016 DC74_RS21850 31a10d5f8dd62542ec7d7ef767187e66 387 SUPERFAMILY SSF53187 5 177 2.32E-59 T 23-04-2016 DC74_RS23135 d17b28d2ea1b95a8ac2afba83ab594a2 264 SUPERFAMILY SSF52540 3 231 1.28E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23135 d17b28d2ea1b95a8ac2afba83ab594a2 264 Gene3D G3DSA:3.40.50.300 5 244 5.6E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23135 d17b28d2ea1b95a8ac2afba83ab594a2 264 Pfam PF00005 ABC transporter 19 167 5.3E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS23135 d17b28d2ea1b95a8ac2afba83ab594a2 264 PANTHER PTHR24220:SF309 4 255 1.2E-98 T 23-04-2016 DC74_RS23135 d17b28d2ea1b95a8ac2afba83ab594a2 264 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS23135 d17b28d2ea1b95a8ac2afba83ab594a2 264 SMART SM00382 27 218 1.4E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS23135 d17b28d2ea1b95a8ac2afba83ab594a2 264 PANTHER PTHR24220 4 255 1.2E-98 T 23-04-2016 DC74_RS31030 52aa02700ea958c8f8f9a66a079cdd87 427 Pfam PF01757 Acyltransferase family 46 394 4.9E-29 T 23-04-2016 IPR002656 Acyltransferase 3 GO:0016747 DC74_RS31030 52aa02700ea958c8f8f9a66a079cdd87 427 PANTHER PTHR23028 16 410 3.2E-41 T 23-04-2016 DC74_RS11105 d2156bd23797b8d8b609a324a4e9125e 467 Pfam PF14684 Tricorn protease C1 domain 134 198 9.8E-12 T 23-04-2016 IPR028204 Tricorn protease C1 domain DC74_RS11105 d2156bd23797b8d8b609a324a4e9125e 467 PANTHER PTHR11261:SF2 130 443 8.6E-12 T 23-04-2016 DC74_RS11105 d2156bd23797b8d8b609a324a4e9125e 467 SUPERFAMILY SSF52096 246 456 5.63E-40 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS11105 d2156bd23797b8d8b609a324a4e9125e 467 SUPERFAMILY SSF52096 132 216 5.63E-40 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS11105 d2156bd23797b8d8b609a324a4e9125e 467 Pfam PF03572 Peptidase family S41 252 438 8.9E-23 T 23-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 DC74_RS11105 d2156bd23797b8d8b609a324a4e9125e 467 Gene3D G3DSA:3.90.226.10 245 465 4.0E-27 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS11105 d2156bd23797b8d8b609a324a4e9125e 467 Gene3D G3DSA:3.30.750.44 129 197 4.7E-12 T 23-04-2016 DC74_RS11105 d2156bd23797b8d8b609a324a4e9125e 467 PANTHER PTHR11261 130 443 8.6E-12 T 23-04-2016 DC74_RS11105 d2156bd23797b8d8b609a324a4e9125e 467 SMART SM00245 223 441 0.0042 T 23-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 DC74_RS39670 e15797dd1c33fee0dd335c2fde884898 279 Pfam PF13460 NAD(P)H-binding 6 179 2.3E-25 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39670 e15797dd1c33fee0dd335c2fde884898 279 SUPERFAMILY SSF51735 2 274 1.36E-53 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39670 e15797dd1c33fee0dd335c2fde884898 279 PANTHER PTHR14194 1 279 1.1E-96 T 23-04-2016 DC74_RS39670 e15797dd1c33fee0dd335c2fde884898 279 Gene3D G3DSA:3.40.50.720 2 213 2.3E-42 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39670 e15797dd1c33fee0dd335c2fde884898 279 PANTHER PTHR14194:SF21 1 279 1.1E-96 T 23-04-2016 DC74_RS37545 f944328382481d90b8cdab35331de6b8 233 Gene3D G3DSA:3.90.1560.10 8 214 2.8E-46 T 23-04-2016 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 DC74_RS37545 f944328382481d90b8cdab35331de6b8 233 PANTHER PTHR37311:SF1 1 224 8.3E-54 T 23-04-2016 DC74_RS37545 f944328382481d90b8cdab35331de6b8 233 PANTHER PTHR37311 1 224 8.3E-54 T 23-04-2016 DC74_RS37545 f944328382481d90b8cdab35331de6b8 233 Pfam PF04029 2-phosphosulpholactate phosphatase 13 198 4.6E-31 T 23-04-2016 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 DC74_RS37545 f944328382481d90b8cdab35331de6b8 233 SUPERFAMILY SSF142823 9 210 1.96E-37 T 23-04-2016 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 24 769 1.5E-167 T 23-04-2016 IPR005887 Alpha-1,2-mannosidase, putative KEGG: 00130+3.2.1.-|KEGG: 00531+3.2.1.- DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 PANTHER PTHR12143 40 386 4.5E-127 T 23-04-2016 DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 PANTHER PTHR12143 468 773 4.5E-127 T 23-04-2016 DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 PANTHER PTHR12143 402 450 4.5E-127 T 23-04-2016 DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 Gene3D G3DSA:1.20.1050.60 362 452 2.9E-25 T 23-04-2016 DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 Pfam PF07971 Glycosyl hydrolase family 92 255 766 7.6E-140 T 23-04-2016 IPR012939 Glycosyl hydrolase family 92 DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 SUPERFAMILY SSF48208 285 753 6.97E-28 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 Gene3D G3DSA:3.30.2080.10 628 777 1.7E-49 T 23-04-2016 DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 Gene3D G3DSA:1.20.1610.10 460 627 1.6E-46 T 23-04-2016 DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 Gene3D G3DSA:2.70.98.10 42 338 3.9E-94 T 23-04-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 PANTHER PTHR12143:SF22 40 386 4.5E-127 T 23-04-2016 DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 PANTHER PTHR12143:SF22 468 773 4.5E-127 T 23-04-2016 DC74_RS33635 353bfa9ac320949b8ccecc764a6273ab 801 PANTHER PTHR12143:SF22 402 450 4.5E-127 T 23-04-2016 DC74_RS14415 ce0085e3d5f36b559cd1e24a6e3bea54 219 PANTHER PTHR22769 92 205 4.0E-12 T 23-04-2016 DC74_RS14415 ce0085e3d5f36b559cd1e24a6e3bea54 219 Gene3D G3DSA:3.90.79.10 94 206 8.3E-22 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS14415 ce0085e3d5f36b559cd1e24a6e3bea54 219 Pfam PF00293 NUDIX domain 92 198 2.5E-13 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS14415 ce0085e3d5f36b559cd1e24a6e3bea54 219 SUPERFAMILY SSF55811 93 214 7.45E-24 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS16485 69a1cb912ece1931fc2e9c9111682313 391 PANTHER PTHR11579:SF0 5 43 1.2E-41 T 23-04-2016 DC74_RS16485 69a1cb912ece1931fc2e9c9111682313 391 PANTHER PTHR11579:SF0 79 250 1.2E-41 T 23-04-2016 DC74_RS16485 69a1cb912ece1931fc2e9c9111682313 391 Gene3D G3DSA:3.40.50.150 14 252 1.8E-44 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS16485 69a1cb912ece1931fc2e9c9111682313 391 PANTHER PTHR11579 5 43 1.2E-41 T 23-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 DC74_RS16485 69a1cb912ece1931fc2e9c9111682313 391 PANTHER PTHR11579 79 250 1.2E-41 T 23-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 DC74_RS16485 69a1cb912ece1931fc2e9c9111682313 391 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 94 244 1.1E-21 T 23-04-2016 DC74_RS16485 69a1cb912ece1931fc2e9c9111682313 391 SUPERFAMILY SSF53335 15 57 2.15E-23 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS16485 69a1cb912ece1931fc2e9c9111682313 391 SUPERFAMILY SSF53335 95 209 2.15E-23 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS01630 a62e8d5db6f58b3d1d13a0c76c1f611d 304 PANTHER PTHR10366:SF475 2 290 1.6E-95 T 23-04-2016 DC74_RS01630 a62e8d5db6f58b3d1d13a0c76c1f611d 304 SUPERFAMILY SSF51735 1 281 5.62E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01630 a62e8d5db6f58b3d1d13a0c76c1f611d 304 PANTHER PTHR10366 2 290 1.6E-95 T 23-04-2016 DC74_RS01630 a62e8d5db6f58b3d1d13a0c76c1f611d 304 Gene3D G3DSA:3.40.50.720 1 281 3.0E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01630 a62e8d5db6f58b3d1d13a0c76c1f611d 304 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 209 3.1E-15 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS04695 62cedf4efa6d0a6ee8447f3300e17d0b 195 PANTHER PTHR31462 3 192 8.9E-15 T 23-04-2016 DC74_RS04695 62cedf4efa6d0a6ee8447f3300e17d0b 195 Pfam PF06736 Protein of unknown function (DUF1211) 2 90 7.5E-21 T 23-04-2016 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 DC74_RS04695 62cedf4efa6d0a6ee8447f3300e17d0b 195 PANTHER PTHR31462:SF4 3 192 8.9E-15 T 23-04-2016 DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 Gene3D G3DSA:1.10.10.350 483 572 5.7E-19 T 23-04-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 Pfam PF01921 tRNA synthetases class I (K) 9 399 4.0E-126 T 23-04-2016 DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 Gene3D G3DSA:3.40.50.620 208 215 2.6E-54 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 Gene3D G3DSA:3.40.50.620 18 167 2.6E-54 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 Gene3D G3DSA:3.40.50.620 259 312 2.6E-54 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 SUPERFAMILY SSF52374 217 358 2.94E-46 T 23-04-2016 DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 SUPERFAMILY SSF52374 22 186 2.94E-46 T 23-04-2016 DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 48 - T 23-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 210 571 1.1E-52 T 23-04-2016 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 PANTHER PTHR37940 206 572 5.6E-155 T 23-04-2016 DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 PANTHER PTHR37940 1 171 5.6E-155 T 23-04-2016 DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 8 574 30.165 T 23-04-2016 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 SUPERFAMILY SSF48163 364 573 1.31E-21 T 23-04-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 DC74_RS19400 a160d856f31bb82d4011490065fb763e 574 Gene3D G3DSA:2.30.30.300 216 254 1.6E-10 T 23-04-2016 IPR023386 Lysine-tRNA ligase, insertion domain GO:0004824 KEGG: 00970+6.1.1.6 DC74_RS18255 fcfcf46d089f7a578aa4e128bca9abbd 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS18255 fcfcf46d089f7a578aa4e128bca9abbd 548 Gene3D G3DSA:3.30.300.30 440 537 3.1E-29 T 23-04-2016 DC74_RS18255 fcfcf46d089f7a578aa4e128bca9abbd 548 SUPERFAMILY SSF56801 14 537 1.57E-147 T 23-04-2016 DC74_RS18255 fcfcf46d089f7a578aa4e128bca9abbd 548 Gene3D G3DSA:3.40.50.980 202 355 4.3E-38 T 23-04-2016 DC74_RS18255 fcfcf46d089f7a578aa4e128bca9abbd 548 PANTHER PTHR24096 16 541 1.2E-163 T 23-04-2016 DC74_RS18255 fcfcf46d089f7a578aa4e128bca9abbd 548 Gene3D G3DSA:2.30.38.10 365 439 4.4E-28 T 23-04-2016 DC74_RS18255 fcfcf46d089f7a578aa4e128bca9abbd 548 Gene3D G3DSA:3.40.50.980 16 201 3.8E-34 T 23-04-2016 DC74_RS18255 fcfcf46d089f7a578aa4e128bca9abbd 548 PANTHER PTHR24096:SF214 16 541 1.2E-163 T 23-04-2016 DC74_RS18255 fcfcf46d089f7a578aa4e128bca9abbd 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 529 3.1E-20 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS18255 fcfcf46d089f7a578aa4e128bca9abbd 548 Pfam PF00501 AMP-binding enzyme 22 445 3.1E-96 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS04795 a07794142e2d249b1ded48430ca672a1 319 Gene3D G3DSA:1.10.1660.10 13 119 1.0E-23 T 23-04-2016 DC74_RS04795 a07794142e2d249b1ded48430ca672a1 319 Pfam PF00376 MerR family regulatory protein 13 48 2.6E-13 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS04795 a07794142e2d249b1ded48430ca672a1 319 PANTHER PTHR30204 3 101 4.2E-17 T 23-04-2016 DC74_RS04795 a07794142e2d249b1ded48430ca672a1 319 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 8.9E-6 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS04795 a07794142e2d249b1ded48430ca672a1 319 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 8.9E-6 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS04795 a07794142e2d249b1ded48430ca672a1 319 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 8.9E-6 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS04795 a07794142e2d249b1ded48430ca672a1 319 SMART SM00422 13 80 1.9E-17 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS04795 a07794142e2d249b1ded48430ca672a1 319 SUPERFAMILY SSF46955 13 113 4.4E-21 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS09510 cabf25d5c5f7501b54d2d0649b8c0ef4 278 SUPERFAMILY SSF51735 108 262 1.08E-21 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09510 cabf25d5c5f7501b54d2d0649b8c0ef4 278 SUPERFAMILY SSF53223 7 107 2.59E-26 T 23-04-2016 DC74_RS09510 cabf25d5c5f7501b54d2d0649b8c0ef4 278 PANTHER PTHR21089 4 278 1.2E-65 T 23-04-2016 DC74_RS09510 cabf25d5c5f7501b54d2d0649b8c0ef4 278 Gene3D G3DSA:3.40.50.720 113 274 2.9E-31 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09510 cabf25d5c5f7501b54d2d0649b8c0ef4 278 Gene3D G3DSA:3.40.192.10 5 112 8.1E-37 T 23-04-2016 DC74_RS09510 cabf25d5c5f7501b54d2d0649b8c0ef4 278 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 94 8.4E-23 T 23-04-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 Pfam PF00067 Cytochrome P450 93 414 1.3E-28 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 365 374 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 Gene3D G3DSA:1.10.630.10 32 419 4.7E-110 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 PRINTS PR00359 B-class P450 signature 215 237 1.0E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 PRINTS PR00359 B-class P450 signature 342 357 1.0E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 PRINTS PR00359 B-class P450 signature 363 372 1.0E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 PRINTS PR00359 B-class P450 signature 152 168 1.0E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 PRINTS PR00359 B-class P450 signature 102 113 1.0E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 PRINTS PR00359 B-class P450 signature 169 184 1.0E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 PRINTS PR00359 B-class P450 signature 314 341 1.0E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 PRINTS PR00359 B-class P450 signature 372 383 1.0E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 PRINTS PR00359 B-class P450 signature 296 307 1.0E-45 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 PANTHER PTHR24286 59 394 7.9E-73 T 23-04-2016 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 SUPERFAMILY SSF48264 33 418 5.11E-85 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03330 0059f658e270341fd53428ea05ff6132 424 PANTHER PTHR24286:SF42 59 394 7.9E-73 T 23-04-2016 DC74_RS09750 f0bb603602f5a31dd59fa9e9f719361f 350 Pfam PF00425 chorismate binding enzyme 74 330 1.6E-71 T 23-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal DC74_RS09750 f0bb603602f5a31dd59fa9e9f719361f 350 PRINTS PR00095 Anthranilate synthase component I signature 183 196 8.3E-8 T 23-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 DC74_RS09750 f0bb603602f5a31dd59fa9e9f719361f 350 PRINTS PR00095 Anthranilate synthase component I signature 266 280 8.3E-8 T 23-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 DC74_RS09750 f0bb603602f5a31dd59fa9e9f719361f 350 PANTHER PTHR11236 46 337 1.1E-99 T 23-04-2016 DC74_RS09750 f0bb603602f5a31dd59fa9e9f719361f 350 Gene3D G3DSA:3.60.120.10 50 340 5.7E-100 T 23-04-2016 IPR005801 ADC synthase GO:0009058 DC74_RS09750 f0bb603602f5a31dd59fa9e9f719361f 350 SUPERFAMILY SSF56322 53 337 1.23E-88 T 23-04-2016 IPR005801 ADC synthase GO:0009058 DC74_RS03585 1b6a20a399bd475c30473078d0958bc2 194 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 159 6.5E-12 T 23-04-2016 DC74_RS03585 1b6a20a399bd475c30473078d0958bc2 194 Gene3D G3DSA:3.40.50.720 1 192 4.2E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03585 1b6a20a399bd475c30473078d0958bc2 194 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 142 8.19E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03585 1b6a20a399bd475c30473078d0958bc2 194 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 160 8.19E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03585 1b6a20a399bd475c30473078d0958bc2 194 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 8.19E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03585 1b6a20a399bd475c30473078d0958bc2 194 SUPERFAMILY SSF51735 3 180 1.84E-22 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS13730 c0dc99e237c2057e28cc7da33e5973cc 493 ProSitePatterns PS00216 Sugar transport proteins signature 1. 338 354 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS13730 c0dc99e237c2057e28cc7da33e5973cc 493 ProSitePatterns PS00217 Sugar transport proteins signature 2. 159 184 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS13730 c0dc99e237c2057e28cc7da33e5973cc 493 Gene3D G3DSA:1.20.1250.20 281 468 4.6E-25 T 23-04-2016 DC74_RS13730 c0dc99e237c2057e28cc7da33e5973cc 493 Gene3D G3DSA:1.20.1250.20 48 261 3.4E-28 T 23-04-2016 DC74_RS13730 c0dc99e237c2057e28cc7da33e5973cc 493 PANTHER PTHR23508:SF17 26 486 3.9E-267 T 23-04-2016 DC74_RS13730 c0dc99e237c2057e28cc7da33e5973cc 493 PANTHER PTHR23508 26 486 3.9E-267 T 23-04-2016 DC74_RS13730 c0dc99e237c2057e28cc7da33e5973cc 493 Pfam PF00083 Sugar (and other) transporter 52 470 6.6E-45 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS13730 c0dc99e237c2057e28cc7da33e5973cc 493 SUPERFAMILY SSF103473 42 470 1.57E-73 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS01150 d424cccdce1558da1b33096ac5e5d922 289 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 70 279 5.6E-23 T 23-04-2016 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal DC74_RS01150 d424cccdce1558da1b33096ac5e5d922 289 SUPERFAMILY SSF53474 21 248 8.96E-20 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01150 d424cccdce1558da1b33096ac5e5d922 289 PANTHER PTHR10824:SF4 26 241 4.1E-16 T 23-04-2016 DC74_RS01150 d424cccdce1558da1b33096ac5e5d922 289 Gene3D G3DSA:3.40.50.1820 183 275 1.1E-19 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01150 d424cccdce1558da1b33096ac5e5d922 289 Gene3D G3DSA:3.40.50.1820 25 124 1.1E-19 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01150 d424cccdce1558da1b33096ac5e5d922 289 PANTHER PTHR10824 26 241 4.1E-16 T 23-04-2016 DC74_RS34735 da9c460cb65ad52cf7d32ab71617cb82 258 SUPERFAMILY SSF53335 23 241 5.84E-39 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS34735 da9c460cb65ad52cf7d32ab71617cb82 258 Gene3D G3DSA:3.40.50.150 22 201 7.1E-39 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS34735 da9c460cb65ad52cf7d32ab71617cb82 258 PANTHER PTHR10108 27 214 9.3E-31 T 23-04-2016 DC74_RS34735 da9c460cb65ad52cf7d32ab71617cb82 258 Pfam PF08241 Methyltransferase domain 46 143 1.1E-22 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 SMART SM00421 152 209 2.1E-23 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 Gene3D G3DSA:1.10.10.10 126 216 1.3E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 SUPERFAMILY SSF46894 147 215 2.18E-20 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 8.2E-17 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 Pfam PF00072 Response regulator receiver domain 4 117 4.5E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 SMART SM00448 2 117 5.5E-29 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 Gene3D G3DSA:3.40.50.2300 2 125 1.2E-37 T 23-04-2016 DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 PANTHER PTHR26402:SF564 2 216 3.4E-92 T 23-04-2016 DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.5E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.5E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.5E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 PANTHER PTHR26402 2 216 3.4E-92 T 23-04-2016 DC74_RS08840 66c7d41f0940a8a47ed178a6a8dc35c9 221 SUPERFAMILY SSF52172 2 127 5.83E-33 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS16760 2f80e47666685c00d2b84463a7986619 533 PANTHER PTHR11731 229 326 1.9E-25 T 23-04-2016 DC74_RS16760 2f80e47666685c00d2b84463a7986619 533 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 31 359 2.9E-49 T 23-04-2016 IPR005674 CocE/Serine esterase GO:0016787 DC74_RS16760 2f80e47666685c00d2b84463a7986619 533 PANTHER PTHR11731 31 185 1.9E-25 T 23-04-2016 DC74_RS16760 2f80e47666685c00d2b84463a7986619 533 PANTHER PTHR11731:SF151 229 326 1.9E-25 T 23-04-2016 DC74_RS16760 2f80e47666685c00d2b84463a7986619 533 SUPERFAMILY SSF53474 30 341 2.65E-41 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS16760 2f80e47666685c00d2b84463a7986619 533 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 30 291 2.1E-51 T 23-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 DC74_RS16760 2f80e47666685c00d2b84463a7986619 533 Gene3D G3DSA:3.40.50.1820 7 163 1.1E-60 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS16760 2f80e47666685c00d2b84463a7986619 533 Gene3D G3DSA:3.40.50.1820 233 338 1.1E-60 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS16760 2f80e47666685c00d2b84463a7986619 533 PANTHER PTHR11731:SF151 31 185 1.9E-25 T 23-04-2016 DC74_RS17040 21541bcb1dcf68b7df70c6cfdcca373d 342 SUPERFAMILY SSF53448 5 248 4.5E-44 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS17040 21541bcb1dcf68b7df70c6cfdcca373d 342 Gene3D G3DSA:3.90.550.10 7 239 2.7E-38 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS17040 21541bcb1dcf68b7df70c6cfdcca373d 342 Pfam PF00535 Glycosyl transferase family 2 10 173 8.9E-22 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS17040 21541bcb1dcf68b7df70c6cfdcca373d 342 PANTHER PTHR22916 1 217 7.8E-34 T 23-04-2016 DC74_RS28820 ffb2a29c306a02bfc9b1e838f390b68b 261 SMART SM00382 45 232 5.5E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS28820 ffb2a29c306a02bfc9b1e838f390b68b 261 Pfam PF00005 ABC transporter 36 184 8.1E-36 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS28820 ffb2a29c306a02bfc9b1e838f390b68b 261 SUPERFAMILY SSF52540 21 254 8.16E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28820 ffb2a29c306a02bfc9b1e838f390b68b 261 PIRSF PIRSF039085 17 260 1.9E-112 T 23-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 DC74_RS28820 ffb2a29c306a02bfc9b1e838f390b68b 261 Gene3D G3DSA:3.40.50.300 19 256 9.3E-84 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28820 ffb2a29c306a02bfc9b1e838f390b68b 261 PANTHER PTHR24220 22 261 1.3E-148 T 23-04-2016 DC74_RS28820 ffb2a29c306a02bfc9b1e838f390b68b 261 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS28820 ffb2a29c306a02bfc9b1e838f390b68b 261 PANTHER PTHR24220:SF550 22 261 1.3E-148 T 23-04-2016 DC74_RS24955 dd92792c181f6b28287e23f211a3640b 302 PANTHER PTHR30346 8 296 8.0E-127 T 23-04-2016 DC74_RS24955 dd92792c181f6b28287e23f211a3640b 302 SUPERFAMILY SSF53850 97 298 1.97E-42 T 23-04-2016 DC74_RS24955 dd92792c181f6b28287e23f211a3640b 302 Gene3D G3DSA:1.10.10.10 14 93 2.4E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24955 dd92792c181f6b28287e23f211a3640b 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 70 7.2E-20 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS24955 dd92792c181f6b28287e23f211a3640b 302 PANTHER PTHR30346:SF8 8 296 8.0E-127 T 23-04-2016 DC74_RS24955 dd92792c181f6b28287e23f211a3640b 302 SUPERFAMILY SSF46785 14 92 1.82E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24955 dd92792c181f6b28287e23f211a3640b 302 Gene3D G3DSA:3.40.190.10 98 183 3.4E-21 T 23-04-2016 DC74_RS24955 dd92792c181f6b28287e23f211a3640b 302 Pfam PF03466 LysR substrate binding domain 96 296 1.5E-48 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS24955 dd92792c181f6b28287e23f211a3640b 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 3.3E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS24955 dd92792c181f6b28287e23f211a3640b 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 3.3E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS24955 dd92792c181f6b28287e23f211a3640b 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 3.3E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS24955 dd92792c181f6b28287e23f211a3640b 302 Gene3D G3DSA:3.40.190.10 184 271 1.3E-30 T 23-04-2016 DC74_RS13780 fc2854a8a915a3aa19fc4a7b1767b6b2 178 Gene3D G3DSA:3.40.630.30 19 169 7.8E-29 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS13780 fc2854a8a915a3aa19fc4a7b1767b6b2 178 PANTHER PTHR13947 21 166 1.1E-19 T 23-04-2016 DC74_RS13780 fc2854a8a915a3aa19fc4a7b1767b6b2 178 Pfam PF00583 Acetyltransferase (GNAT) family 76 149 9.7E-15 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS13780 fc2854a8a915a3aa19fc4a7b1767b6b2 178 SUPERFAMILY SSF55729 21 168 1.95E-27 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS19295 c70455ed5d136fcc0a72fc2f1ba34cfc 361 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 116 359 2.5E-77 T 23-04-2016 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 DC74_RS19295 c70455ed5d136fcc0a72fc2f1ba34cfc 361 PANTHER PTHR30071:SF5 105 359 5.9E-71 T 23-04-2016 DC74_RS19295 c70455ed5d136fcc0a72fc2f1ba34cfc 361 PANTHER PTHR30071 105 359 5.9E-71 T 23-04-2016 DC74_RS19295 c70455ed5d136fcc0a72fc2f1ba34cfc 361 Pfam PF01578 Cytochrome C assembly protein 138 356 3.2E-47 T 23-04-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 DC74_RS25640 e29590324add4501bd741b5544684b99 461 PANTHER PTHR11785 20 456 2.2E-169 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS25640 e29590324add4501bd741b5544684b99 461 Pfam PF00324 Amino acid permease 42 421 2.9E-30 T 23-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 DC74_RS25640 e29590324add4501bd741b5544684b99 461 PIRSF PIRSF006060 5 457 5.7E-50 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS25640 e29590324add4501bd741b5544684b99 461 PANTHER PTHR11785:SF197 20 456 2.2E-169 T 23-04-2016 DC74_RS38895 43831b5b8cc61cdbab623a46cd6c274c 192 ProSitePatterns PS01117 MarR-type HTH domain signature. 86 120 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS38895 43831b5b8cc61cdbab623a46cd6c274c 192 SUPERFAMILY SSF46785 20 161 1.15E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38895 43831b5b8cc61cdbab623a46cd6c274c 192 Pfam PF01047 MarR family 55 112 1.0E-14 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS38895 43831b5b8cc61cdbab623a46cd6c274c 192 Gene3D G3DSA:1.10.10.10 19 160 6.1E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38895 43831b5b8cc61cdbab623a46cd6c274c 192 PANTHER PTHR33164 4 173 3.7E-32 T 23-04-2016 DC74_RS38895 43831b5b8cc61cdbab623a46cd6c274c 192 SMART SM00347 45 147 1.3E-17 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS38895 43831b5b8cc61cdbab623a46cd6c274c 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 87 7.92E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS38895 43831b5b8cc61cdbab623a46cd6c274c 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 123 7.92E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS38895 43831b5b8cc61cdbab623a46cd6c274c 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 103 7.92E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS38895 43831b5b8cc61cdbab623a46cd6c274c 192 PRINTS PR00598 Bacterial regulatory protein MarR family signature 137 157 7.92E-6 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS38895 43831b5b8cc61cdbab623a46cd6c274c 192 PANTHER PTHR33164:SF10 4 173 3.7E-32 T 23-04-2016 DC74_RS22970 707f9a7556520c7f28351e89a966cbf9 508 PANTHER PTHR26402 189 494 5.9E-46 T 23-04-2016 DC74_RS22970 707f9a7556520c7f28351e89a966cbf9 508 PANTHER PTHR26402 111 168 5.9E-46 T 23-04-2016 DC74_RS22970 707f9a7556520c7f28351e89a966cbf9 508 SUPERFAMILY SSF52172 184 268 4.83E-7 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS22970 707f9a7556520c7f28351e89a966cbf9 508 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 312 507 2.3E-37 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS22970 707f9a7556520c7f28351e89a966cbf9 508 PANTHER PTHR26402:SF517 189 494 5.9E-46 T 23-04-2016 DC74_RS22970 707f9a7556520c7f28351e89a966cbf9 508 PANTHER PTHR26402:SF517 111 168 5.9E-46 T 23-04-2016 DC74_RS22970 707f9a7556520c7f28351e89a966cbf9 508 Gene3D G3DSA:3.40.50.2300 131 250 5.5E-11 T 23-04-2016 DC74_RS22970 707f9a7556520c7f28351e89a966cbf9 508 SMART SM00331 286 507 5.9E-17 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS04990 66095f737f93c0a5e42798a298220c81 175 SUPERFAMILY SSF53056 4 167 4.58E-20 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS04990 66095f737f93c0a5e42798a298220c81 175 Pfam PF00484 Carbonic anhydrase 31 104 1.5E-7 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS04990 66095f737f93c0a5e42798a298220c81 175 SMART SM00947 23 168 5.3E-11 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS04990 66095f737f93c0a5e42798a298220c81 175 Gene3D G3DSA:3.40.1050.10 4 167 4.2E-23 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS30325 84c7669616ae2a8eecc6e36b08538305 200 Gene3D G3DSA:3.30.420.10 128 199 4.4E-14 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS30325 84c7669616ae2a8eecc6e36b08538305 200 Pfam PF13276 HTH-like domain 46 102 8.5E-18 T 23-04-2016 IPR025948 HTH-like domain DC74_RS30325 84c7669616ae2a8eecc6e36b08538305 200 SUPERFAMILY SSF53098 127 199 2.47E-16 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS30325 84c7669616ae2a8eecc6e36b08538305 200 Pfam PF00665 Integrase core domain 132 199 3.0E-14 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 DC74_RS30325 84c7669616ae2a8eecc6e36b08538305 200 PANTHER PTHR32552 7 199 4.4E-33 T 23-04-2016 DC74_RS33500 cb116a28874a3da08ce6ed912764579a 308 SUPERFAMILY SSF52129 83 221 4.81E-7 T 23-04-2016 IPR029030 Caspase-like domain DC74_RS33500 cb116a28874a3da08ce6ed912764579a 308 Pfam PF00656 Caspase domain 68 203 3.2E-6 T 23-04-2016 DC74_RS16520 62595713c0e81e76acf7bb7759718279 338 SUPERFAMILY SSF53850 60 333 1.48E-53 T 23-04-2016 DC74_RS16520 62595713c0e81e76acf7bb7759718279 338 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 60 327 1.6E-55 T 23-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 DC74_RS16520 62595713c0e81e76acf7bb7759718279 338 Gene3D G3DSA:3.40.190.10 283 334 3.6E-47 T 23-04-2016 DC74_RS16520 62595713c0e81e76acf7bb7759718279 338 Gene3D G3DSA:3.40.190.10 58 165 3.6E-47 T 23-04-2016 DC74_RS16520 62595713c0e81e76acf7bb7759718279 338 PANTHER PTHR30177 55 333 1.9E-93 T 23-04-2016 DC74_RS16520 62595713c0e81e76acf7bb7759718279 338 PANTHER PTHR30177:SF9 55 333 1.9E-93 T 23-04-2016 DC74_RS16520 62595713c0e81e76acf7bb7759718279 338 Gene3D G3DSA:3.40.190.120 166 271 2.0E-31 T 23-04-2016 DC74_RS02465 07105cee90133ff2d8a5de3d819d5175 211 PANTHER PTHR10108 1 106 1.7E-16 T 23-04-2016 DC74_RS02465 07105cee90133ff2d8a5de3d819d5175 211 Pfam PF08241 Methyltransferase domain 2 85 5.7E-15 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS02465 07105cee90133ff2d8a5de3d819d5175 211 SUPERFAMILY SSF53335 1 145 5.57E-23 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS02465 07105cee90133ff2d8a5de3d819d5175 211 Gene3D G3DSA:3.40.50.150 1 140 7.1E-22 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS02465 07105cee90133ff2d8a5de3d819d5175 211 PANTHER PTHR10108:SF730 1 106 1.7E-16 T 23-04-2016 DC74_RS03715 1824eef151f6cb52fa888b6c1c71f765 123 SUPERFAMILY SSF52091 17 110 1.41E-17 T 23-04-2016 IPR002645 STAS domain DC74_RS03715 1824eef151f6cb52fa888b6c1c71f765 123 Gene3D G3DSA:3.30.750.24 17 111 8.9E-19 T 23-04-2016 IPR002645 STAS domain DC74_RS03715 1824eef151f6cb52fa888b6c1c71f765 123 Pfam PF13466 STAS domain 24 104 1.1E-12 T 23-04-2016 IPR002645 STAS domain DC74_RS32485 faf8d7b53dc17809f58ba8d66811fb72 288 Gene3D G3DSA:2.40.10.10 88 165 1.8E-13 T 23-04-2016 DC74_RS32485 faf8d7b53dc17809f58ba8d66811fb72 288 SUPERFAMILY SSF50494 73 274 1.08E-19 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS32485 faf8d7b53dc17809f58ba8d66811fb72 288 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 107 112 - T 23-04-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 DC74_RS26885 a1616abac2891dd662fe64bb2e0590a3 281 PANTHER PTHR18895:SF64 7 280 1.7E-88 T 23-04-2016 DC74_RS26885 a1616abac2891dd662fe64bb2e0590a3 281 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 278 42.665 T 23-04-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 DC74_RS26885 a1616abac2891dd662fe64bb2e0590a3 281 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 12 279 1.1E-51 T 23-04-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 DC74_RS26885 a1616abac2891dd662fe64bb2e0590a3 281 Gene3D G3DSA:1.10.8.10 8 83 3.3E-20 T 23-04-2016 DC74_RS26885 a1616abac2891dd662fe64bb2e0590a3 281 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 26 274 3.2E-73 T 23-04-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 DC74_RS26885 a1616abac2891dd662fe64bb2e0590a3 281 Gene3D G3DSA:3.40.50.150 85 278 9.5E-57 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS26885 a1616abac2891dd662fe64bb2e0590a3 281 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 181 187 - T 23-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 DC74_RS26885 a1616abac2891dd662fe64bb2e0590a3 281 Pfam PF13649 Methyltransferase domain 115 199 4.8E-13 T 23-04-2016 DC74_RS26885 a1616abac2891dd662fe64bb2e0590a3 281 SUPERFAMILY SSF53335 14 248 1.42E-49 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS26885 a1616abac2891dd662fe64bb2e0590a3 281 PANTHER PTHR18895 7 280 1.7E-88 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PIRSF PIRSF037149 7 853 0.0 T 23-04-2016 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 SUPERFAMILY SSF51905 13 196 6.75E-39 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PANTHER PTHR11493:SF52 426 853 4.7E-252 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PANTHER PTHR11493:SF52 10 265 4.7E-252 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 8.0E-9 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 8.0E-9 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 128 8.0E-9 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 8.0E-9 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 Gene3D G3DSA:3.30.413.10 650 786 9.9E-33 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PANTHER PTHR11493 426 853 4.7E-252 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PANTHER PTHR11493 10 265 4.7E-252 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 Gene3D G3DSA:3.50.50.60 114 319 2.5E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PRINTS PR00397 Sirohaem Fe-binding site signature 654 672 8.7E-6 T 23-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PRINTS PR00397 Sirohaem Fe-binding site signature 697 715 8.7E-6 T 23-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 Pfam PF04324 BFD-like [2Fe-2S] binding domain 430 478 3.5E-11 T 23-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 6.1E-7 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 286 293 6.1E-7 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 244 258 6.1E-7 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 6.1E-7 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 SUPERFAMILY SSF51905 152 321 8.22E-25 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 SUPERFAMILY SSF55124 530 659 1.8E-21 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 Gene3D G3DSA:3.50.50.60 13 113 7.2E-24 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 296 2.5E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 697 713 - T 23-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 578 638 1.4E-9 T 23-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 14 819 0.0 T 23-04-2016 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 UniPathway: UPA00653 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 SUPERFAMILY SSF56014 651 825 6.15E-49 T 23-04-2016 DC74_RS14725 f482f6843d874b84a220fc865461ebb9 879 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 650 786 3.8E-18 T 23-04-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 SUPERFAMILY SSF46955 32 137 5.13E-26 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 SUPERFAMILY SSF89082 189 280 3.53E-20 T 23-04-2016 IPR012925 TipAS antibiotic-recognition domain DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 33 44 2.7E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 57 2.7E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 68 88 2.7E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 Pfam PF13411 MerR HTH family regulatory protein 33 99 1.5E-10 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 Gene3D G3DSA:1.10.490.50 189 280 1.5E-26 T 23-04-2016 IPR012925 TipAS antibiotic-recognition domain DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 Gene3D G3DSA:1.10.1660.10 87 139 3.3E-10 T 23-04-2016 DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 PANTHER PTHR30204:SF5 24 272 7.2E-40 T 23-04-2016 DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 Pfam PF07739 TipAS antibiotic-recognition domain 162 274 8.6E-33 T 23-04-2016 IPR012925 TipAS antibiotic-recognition domain DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 SMART SM00422 32 101 1.1E-23 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 PANTHER PTHR30204 24 272 7.2E-40 T 23-04-2016 DC74_RS31095 8a6fd9834eafe29f61d40839cde44ba0 289 Gene3D G3DSA:1.10.1660.10 32 86 5.4E-21 T 23-04-2016 DC74_RS21190 3f914f5a73f93a492484493475ac2cef 162 SUPERFAMILY SSF110087 25 156 5.36E-33 T 23-04-2016 IPR007410 DR1885-like metal-binding protein DC74_RS21190 3f914f5a73f93a492484493475ac2cef 162 Pfam PF04314 Protein of unknown function (DUF461) 49 149 4.9E-29 T 23-04-2016 IPR007410 DR1885-like metal-binding protein DC74_RS21190 3f914f5a73f93a492484493475ac2cef 162 PANTHER PTHR36302:SF1 8 161 8.6E-25 T 23-04-2016 DC74_RS21190 3f914f5a73f93a492484493475ac2cef 162 PANTHER PTHR36302 8 161 8.6E-25 T 23-04-2016 DC74_RS15445 9230fd2f587c3262b1cac04c237f164b 318 SUPERFAMILY SSF103481 58 165 1.57E-10 T 23-04-2016 DC74_RS15445 9230fd2f587c3262b1cac04c237f164b 318 PANTHER PTHR12715 17 311 2.7E-79 T 23-04-2016 DC74_RS15445 9230fd2f587c3262b1cac04c237f164b 318 PANTHER PTHR12715:SF12 17 311 2.7E-79 T 23-04-2016 DC74_RS15445 9230fd2f587c3262b1cac04c237f164b 318 SUPERFAMILY SSF103481 216 315 2.75E-13 T 23-04-2016 DC74_RS15445 9230fd2f587c3262b1cac04c237f164b 318 Pfam PF00892 EamA-like transporter family 178 311 2.1E-19 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS15445 9230fd2f587c3262b1cac04c237f164b 318 Pfam PF00892 EamA-like transporter family 25 161 7.1E-20 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS17045 0a171a76eb18cd83656d3ffb35aadf06 455 PANTHER PTHR33392:SF6 2 403 1.5E-99 T 23-04-2016 DC74_RS17045 0a171a76eb18cd83656d3ffb35aadf06 455 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 79 232 5.3E-47 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS17045 0a171a76eb18cd83656d3ffb35aadf06 455 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 342 426 4.7E-12 T 23-04-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain DC74_RS17045 0a171a76eb18cd83656d3ffb35aadf06 455 PANTHER PTHR33392 2 403 1.5E-99 T 23-04-2016 DC74_RS17045 0a171a76eb18cd83656d3ffb35aadf06 455 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 79 232 6.3E-47 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS20840 28cd77b202702618fbae23ced8aa5a68 291 Gene3D G3DSA:2.40.10.10 195 275 1.6E-4 T 23-04-2016 DC74_RS20840 28cd77b202702618fbae23ced8aa5a68 291 SUPERFAMILY SSF50494 83 276 1.3E-19 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS20840 28cd77b202702618fbae23ced8aa5a68 291 Gene3D G3DSA:2.40.10.10 92 174 2.8E-12 T 23-04-2016 DC74_RS20840 28cd77b202702618fbae23ced8aa5a68 291 Pfam PF00089 Trypsin 91 263 1.7E-6 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS20840 28cd77b202702618fbae23ced8aa5a68 291 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 111 116 - T 23-04-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 DC74_RS37720 f14d3a353d58faafbf2fde5842e0effc 110 Pfam PF12840 Helix-turn-helix domain 14 88 1.1E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37720 f14d3a353d58faafbf2fde5842e0effc 110 SMART SM00418 14 108 8.2E-8 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS37720 f14d3a353d58faafbf2fde5842e0effc 110 Gene3D G3DSA:1.10.10.10 11 107 1.7E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37720 f14d3a353d58faafbf2fde5842e0effc 110 PANTHER PTHR33154 51 106 8.7E-20 T 23-04-2016 DC74_RS37720 f14d3a353d58faafbf2fde5842e0effc 110 PANTHER PTHR33154 11 35 8.7E-20 T 23-04-2016 DC74_RS37720 f14d3a353d58faafbf2fde5842e0effc 110 SUPERFAMILY SSF46785 11 106 3.46E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04100 20217b8da0de0bdc7fb781b838842e52 245 SUPERFAMILY SSF47090 51 111 7.53E-6 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS04100 20217b8da0de0bdc7fb781b838842e52 245 Gene3D G3DSA:2.40.440.10 132 239 1.1E-10 T 23-04-2016 DC74_RS04100 20217b8da0de0bdc7fb781b838842e52 245 Pfam PF03734 L,D-transpeptidase catalytic domain 129 238 1.8E-13 T 23-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 DC74_RS04100 20217b8da0de0bdc7fb781b838842e52 245 PANTHER PTHR30582 129 238 1.5E-14 T 23-04-2016 DC74_RS04100 20217b8da0de0bdc7fb781b838842e52 245 Gene3D G3DSA:1.10.101.10 67 112 4.0E-4 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS04100 20217b8da0de0bdc7fb781b838842e52 245 PANTHER PTHR30582:SF2 129 238 1.5E-14 T 23-04-2016 DC74_RS04100 20217b8da0de0bdc7fb781b838842e52 245 SUPERFAMILY SSF141523 128 239 6.15E-21 T 23-04-2016 DC74_RS33715 5070b50a3451d63d9a4f4b6961fac9b9 440 SUPERFAMILY SSF109854 7 142 7.94E-22 T 23-04-2016 DC74_RS33715 5070b50a3451d63d9a4f4b6961fac9b9 440 SUPERFAMILY SSF56436 174 433 2.64E-78 T 23-04-2016 IPR016187 C-type lectin fold DC74_RS33715 5070b50a3451d63d9a4f4b6961fac9b9 440 Gene3D G3DSA:3.90.1580.10 165 434 8.5E-80 T 23-04-2016 IPR005532 Sulfatase-modifying factor enzyme DC74_RS33715 5070b50a3451d63d9a4f4b6961fac9b9 440 Pfam PF12867 DinB superfamily 16 146 9.6E-28 T 23-04-2016 IPR024775 DinB-like domain DC74_RS33715 5070b50a3451d63d9a4f4b6961fac9b9 440 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 13 430 2.1E-138 T 23-04-2016 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255|UniPathway: UPA01014 DC74_RS33715 5070b50a3451d63d9a4f4b6961fac9b9 440 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 433 53.65 T 23-04-2016 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255|UniPathway: UPA01014 DC74_RS33715 5070b50a3451d63d9a4f4b6961fac9b9 440 PANTHER PTHR23150 9 433 1.2E-115 T 23-04-2016 DC74_RS33715 5070b50a3451d63d9a4f4b6961fac9b9 440 Gene3D G3DSA:1.20.120.450 10 120 3.1E-7 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS33715 5070b50a3451d63d9a4f4b6961fac9b9 440 PANTHER PTHR23150:SF24 9 433 1.2E-115 T 23-04-2016 DC74_RS33715 5070b50a3451d63d9a4f4b6961fac9b9 440 Pfam PF03781 Sulfatase-modifying factor enzyme 1 172 431 3.6E-67 T 23-04-2016 IPR005532 Sulfatase-modifying factor enzyme DC74_RS32350 010e20aea28a533dde4859f5f55edb78 325 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 305 4.0E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32350 010e20aea28a533dde4859f5f55edb78 325 SUPERFAMILY SSF51735 1 318 3.85E-101 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32350 010e20aea28a533dde4859f5f55edb78 325 PANTHER PTHR10366 2 318 7.4E-146 T 23-04-2016 DC74_RS32350 010e20aea28a533dde4859f5f55edb78 325 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 317 1.9E-128 T 23-04-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 DC74_RS32350 010e20aea28a533dde4859f5f55edb78 325 PANTHER PTHR10366:SF41 2 318 7.4E-146 T 23-04-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 DC74_RS32350 010e20aea28a533dde4859f5f55edb78 325 Gene3D G3DSA:3.90.25.10 182 317 1.9E-52 T 23-04-2016 DC74_RS32350 010e20aea28a533dde4859f5f55edb78 325 Gene3D G3DSA:3.40.50.720 1 181 4.7E-63 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS30485 563020f39960780b75b7cc078c3ab533 263 SUPERFAMILY SSF110849 6 91 7.85E-10 T 23-04-2016 IPR003115 ParB/Sulfiredoxin DC74_RS30485 563020f39960780b75b7cc078c3ab533 263 Gene3D G3DSA:3.90.1530.10 6 77 1.6E-9 T 23-04-2016 DC74_RS30485 563020f39960780b75b7cc078c3ab533 263 Pfam PF02195 ParB-like nuclease domain 6 52 4.0E-7 T 23-04-2016 IPR003115 ParB/Sulfiredoxin DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 Gene3D G3DSA:3.30.70.1050 3 118 5.0E-33 T 23-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 Gene3D G3DSA:1.10.3120.10 211 394 4.9E-47 T 23-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 Pfam PF05697 Bacterial trigger factor protein (TF) 3 145 9.9E-40 T 23-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 420 3.6E-40 T 23-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 Hamap MF_00303 Trigger factor [tig]. 1 425 19.51 T 23-04-2016 IPR005215 Trigger factor GO:0015031 DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 Gene3D G3DSA:3.10.50.40 157 210 8.2E-6 T 23-04-2016 DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 SUPERFAMILY SSF109998 245 435 8.76E-40 T 23-04-2016 IPR027304 Trigger factor/SurA domain DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 PANTHER PTHR30560:SF3 1 437 1.9E-112 T 23-04-2016 DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 PIRSF PIRSF003095 1 445 7.3E-124 T 23-04-2016 IPR005215 Trigger factor GO:0015031 DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 SUPERFAMILY SSF54534 133 244 2.75E-21 T 23-04-2016 DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 PANTHER PTHR30560 1 437 1.9E-112 T 23-04-2016 DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 SUPERFAMILY SSF102735 3 131 1.44E-35 T 23-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 157 215 1.6E-7 T 23-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 DC74_RS15330 136dc0385fa0a5f71a50a3de5d5b7dbb 462 TIGRFAM TIGR00115 tig: trigger factor 12 418 1.8E-120 T 23-04-2016 IPR005215 Trigger factor GO:0015031 DC74_RS28295 43aecbcf98502d667d77e4d6a637c399 170 Pfam PF13787 Protein of unknown function with HXXEE motif 9 128 6.7E-18 T 23-04-2016 IPR025671 Protein of unknown function with HXXEE motif DC74_RS14720 a4bdebe298570e42a52ea170658877ed 414 SUPERFAMILY SSF51905 24 307 1.64E-30 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14720 a4bdebe298570e42a52ea170658877ed 414 Gene3D G3DSA:3.50.50.60 9 93 5.2E-15 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14720 a4bdebe298570e42a52ea170658877ed 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.9E-8 T 23-04-2016 DC74_RS14720 a4bdebe298570e42a52ea170658877ed 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 1.9E-8 T 23-04-2016 DC74_RS14720 a4bdebe298570e42a52ea170658877ed 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 1.9E-8 T 23-04-2016 DC74_RS14720 a4bdebe298570e42a52ea170658877ed 414 PANTHER PTHR22912 1 379 3.9E-88 T 23-04-2016 DC74_RS14720 a4bdebe298570e42a52ea170658877ed 414 Gene3D G3DSA:3.50.50.60 94 308 4.8E-40 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14720 a4bdebe298570e42a52ea170658877ed 414 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 21 301 2.3E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS14720 a4bdebe298570e42a52ea170658877ed 414 PANTHER PTHR22912:SF1 1 379 3.9E-88 T 23-04-2016 DC74_RS22835 31e5fc7fdc0a0a4a1b623f26056d0393 393 Gene3D G3DSA:3.40.47.10 13 234 9.7E-17 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22835 31e5fc7fdc0a0a4a1b623f26056d0393 393 Gene3D G3DSA:3.40.47.10 265 390 2.0E-4 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22835 31e5fc7fdc0a0a4a1b623f26056d0393 393 SUPERFAMILY SSF53901 4 239 1.64E-24 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22835 31e5fc7fdc0a0a4a1b623f26056d0393 393 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 218 2.3E-10 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS22835 31e5fc7fdc0a0a4a1b623f26056d0393 393 SUPERFAMILY SSF53901 219 391 4.61E-11 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS08595 596ddd178cf42f9baf3c8185863f045c 67 Gene3D G3DSA:2.40.50.140 1 65 2.5E-31 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS08595 596ddd178cf42f9baf3c8185863f045c 67 SMART SM00357 3 67 8.0E-31 T 23-04-2016 IPR011129 Cold shock protein GO:0003676 DC74_RS08595 596ddd178cf42f9baf3c8185863f045c 67 PANTHER PTHR11544 1 67 7.7E-40 T 23-04-2016 DC74_RS08595 596ddd178cf42f9baf3c8185863f045c 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 3.2E-31 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS08595 596ddd178cf42f9baf3c8185863f045c 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 23-04-2016 IPR019844 Cold-shock conserved site DC74_RS08595 596ddd178cf42f9baf3c8185863f045c 67 SUPERFAMILY SSF50249 1 66 3.0E-25 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS08595 596ddd178cf42f9baf3c8185863f045c 67 PRINTS PR00050 Cold shock protein signature 40 58 1.0E-17 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS08595 596ddd178cf42f9baf3c8185863f045c 67 PRINTS PR00050 Cold shock protein signature 25 34 1.0E-17 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS08595 596ddd178cf42f9baf3c8185863f045c 67 PRINTS PR00050 Cold shock protein signature 4 19 1.0E-17 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS08595 596ddd178cf42f9baf3c8185863f045c 67 PIRSF PIRSF002599 1 67 1.5E-25 T 23-04-2016 IPR012156 Cold shock, CspA GO:0003676 DC74_RS15875 72f3c9f64fe243ba404541efb15ec36e 746 Pfam PF14435 SUKH-4 immunity protein 572 714 1.0E-14 T 23-04-2016 IPR025851 SUKH-4 immunity protein DC74_RS35735 54ab1205057e3f8551bd029c2486304c 383 SUPERFAMILY SSF56601 18 336 3.81E-76 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS35735 54ab1205057e3f8551bd029c2486304c 383 Gene3D G3DSA:3.40.710.10 29 340 3.6E-79 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS35735 54ab1205057e3f8551bd029c2486304c 383 Pfam PF00144 Beta-lactamase 20 334 2.1E-58 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS35735 54ab1205057e3f8551bd029c2486304c 383 PANTHER PTHR22935 18 324 2.7E-65 T 23-04-2016 DC74_RS37590 5b9270bf8e0379444386d362ac49a4c3 314 SUPERFAMILY SSF56349 13 287 1.97E-18 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DC74_RS37590 5b9270bf8e0379444386d362ac49a4c3 314 Gene3D G3DSA:1.10.150.130 21 118 1.9E-6 T 23-04-2016 IPR023109 Integrase/recombinase, N-terminal DC74_RS37590 5b9270bf8e0379444386d362ac49a4c3 314 Pfam PF00589 Phage integrase family 133 284 7.0E-7 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS37590 5b9270bf8e0379444386d362ac49a4c3 314 Gene3D G3DSA:1.10.443.10 133 287 8.8E-16 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS18860 59245c3e9d7b6401037cd9e7545cd246 417 PANTHER PTHR32027:SF0 10 417 2.1E-90 T 23-04-2016 DC74_RS18860 59245c3e9d7b6401037cd9e7545cd246 417 SUPERFAMILY SSF51556 76 363 6.81E-44 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS18860 59245c3e9d7b6401037cd9e7545cd246 417 Gene3D G3DSA:3.20.20.140 97 354 1.3E-53 T 23-04-2016 DC74_RS18860 59245c3e9d7b6401037cd9e7545cd246 417 Pfam PF07969 Amidohydrolase family 86 392 4.3E-10 T 23-04-2016 IPR013108 Amidohydrolase 3 DC74_RS18860 59245c3e9d7b6401037cd9e7545cd246 417 SUPERFAMILY SSF51338 26 89 6.91E-7 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS18860 59245c3e9d7b6401037cd9e7545cd246 417 Gene3D G3DSA:2.30.40.10 18 96 1.3E-8 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS18860 59245c3e9d7b6401037cd9e7545cd246 417 PANTHER PTHR32027 10 417 2.1E-90 T 23-04-2016 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 Gene3D G3DSA:1.10.630.10 3 394 2.3E-137 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 PRINTS PR00359 B-class P450 signature 312 327 9.0E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 PRINTS PR00359 B-class P450 signature 333 342 9.0E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 PRINTS PR00359 B-class P450 signature 131 147 9.0E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 PRINTS PR00359 B-class P450 signature 184 206 9.0E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 PRINTS PR00359 B-class P450 signature 148 163 9.0E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 PRINTS PR00359 B-class P450 signature 284 311 9.0E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 PRINTS PR00359 B-class P450 signature 83 94 9.0E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 PRINTS PR00359 B-class P450 signature 266 277 9.0E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 PRINTS PR00359 B-class P450 signature 342 353 9.0E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 Pfam PF00067 Cytochrome P450 175 363 1.7E-24 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 PANTHER PTHR11712 19 394 6.1E-110 T 23-04-2016 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 SUPERFAMILY SSF48264 7 394 6.68E-103 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04405 0a3d43763fa26c43e03a3683bd39f6a1 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 335 344 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS31325 a5fbdff12788765d0db8f9bd6bc847a5 279 SUPERFAMILY SSF51658 9 270 1.31E-56 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS31325 a5fbdff12788765d0db8f9bd6bc847a5 279 PANTHER PTHR12110 1 271 2.6E-80 T 23-04-2016 DC74_RS31325 a5fbdff12788765d0db8f9bd6bc847a5 279 PIRSF PIRSF006241 4 277 5.6E-79 T 23-04-2016 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 DC74_RS31325 a5fbdff12788765d0db8f9bd6bc847a5 279 PANTHER PTHR12110:SF3 1 271 2.6E-80 T 23-04-2016 DC74_RS31325 a5fbdff12788765d0db8f9bd6bc847a5 279 Gene3D G3DSA:3.20.20.150 7 272 1.2E-67 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS31325 a5fbdff12788765d0db8f9bd6bc847a5 279 Pfam PF01261 Xylose isomerase-like TIM barrel 26 229 7.8E-26 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 65 0.086 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 8.1E-12 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 613 631 6.0E-41 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 658 676 6.0E-41 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 687 705 6.0E-41 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 720 734 6.0E-41 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 SUPERFAMILY SSF52540 558 870 7.34E-78 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 SUPERFAMILY SSF81923 4 157 7.55E-29 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 SUPERFAMILY SSF52540 158 529 8.8E-91 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 643 661 - T 23-04-2016 IPR028299 ClpA/B, conserved site 2 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 Pfam PF07724 AAA domain (Cdc48 subfamily) 608 769 4.9E-53 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 PANTHER PTHR11638:SF120 1 519 0.0 T 23-04-2016 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 Gene3D G3DSA:3.40.50.300 160 343 6.9E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 Gene3D G3DSA:3.40.50.300 564 786 7.8E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 PANTHER PTHR11638 538 870 0.0 T 23-04-2016 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 PANTHER PTHR11638 1 519 0.0 T 23-04-2016 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 776 865 3.0E-19 T 23-04-2016 IPR019489 Clp ATPase, C-terminal DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 23-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 5 871 0.0 T 23-04-2016 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 Gene3D G3DSA:1.10.8.60 345 428 1.9E-35 T 23-04-2016 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 SMART SM01086 776 876 3.1E-28 T 23-04-2016 IPR019489 Clp ATPase, C-terminal DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 Gene3D G3DSA:1.10.8.60 787 877 3.0E-24 T 23-04-2016 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 PANTHER PTHR11638:SF120 538 870 0.0 T 23-04-2016 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 338 1.2E-11 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 Gene3D G3DSA:1.10.1780.10 4 149 7.4E-30 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 SMART SM00382 609 758 7.8E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS19925 346a2bcfa1a79ea385a7c285aa4985b0 883 SMART SM00382 199 346 4.4E-8 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS30165 f0dacaf8e3fbb0a17337b003e3bdac52 108 PIRSF PIRSF028743 1 108 2.1E-34 T 23-04-2016 IPR008634 Gas vesicle protein GvpO GO:0031412 DC74_RS30165 f0dacaf8e3fbb0a17337b003e3bdac52 108 Pfam PF05800 Gas vesicle synthesis protein GvpO 16 106 5.8E-34 T 23-04-2016 IPR008634 Gas vesicle protein GvpO GO:0031412 DC74_RS22210 f25538f752652341a561ba522672cc4b 417 PANTHER PTHR11669:SF8 57 253 9.4E-61 T 23-04-2016 DC74_RS22210 f25538f752652341a561ba522672cc4b 417 PANTHER PTHR11669:SF8 4 25 9.4E-61 T 23-04-2016 DC74_RS22210 f25538f752652341a561ba522672cc4b 417 Gene3D G3DSA:3.40.50.300 4 23 3.4E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22210 f25538f752652341a561ba522672cc4b 417 Gene3D G3DSA:3.40.50.300 55 202 3.4E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22210 f25538f752652341a561ba522672cc4b 417 Pfam PF13177 DNA polymerase III, delta subunit 55 202 2.9E-34 T 23-04-2016 DC74_RS22210 f25538f752652341a561ba522672cc4b 417 PANTHER PTHR11669 57 253 9.4E-61 T 23-04-2016 DC74_RS22210 f25538f752652341a561ba522672cc4b 417 PANTHER PTHR11669 4 25 9.4E-61 T 23-04-2016 DC74_RS22210 f25538f752652341a561ba522672cc4b 417 SUPERFAMILY SSF52540 55 241 1.84E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22210 f25538f752652341a561ba522672cc4b 417 SUPERFAMILY SSF52540 4 23 1.84E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34105 4af6c278adcf22882e6d11ba770dee01 140 PANTHER PTHR30615 5 139 1.8E-28 T 23-04-2016 DC74_RS34105 4af6c278adcf22882e6d11ba770dee01 140 SUPERFAMILY SSF111038 6 138 2.35E-30 T 23-04-2016 IPR001602 Uncharacterised protein family UPF0047 DC74_RS34105 4af6c278adcf22882e6d11ba770dee01 140 PIRSF PIRSF004681 3 140 1.9E-26 T 23-04-2016 IPR001602 Uncharacterised protein family UPF0047 DC74_RS34105 4af6c278adcf22882e6d11ba770dee01 140 Pfam PF01894 Uncharacterised protein family UPF0047 23 135 1.7E-21 T 23-04-2016 IPR001602 Uncharacterised protein family UPF0047 DC74_RS34105 4af6c278adcf22882e6d11ba770dee01 140 PANTHER PTHR30615:SF0 5 139 1.8E-28 T 23-04-2016 DC74_RS34105 4af6c278adcf22882e6d11ba770dee01 140 Gene3D G3DSA:2.60.120.460 4 138 2.7E-30 T 23-04-2016 IPR001602 Uncharacterised protein family UPF0047 DC74_RS38530 8b83711210e5d1da13c96605c7ea800b 190 PANTHER PTHR38011:SF2 2 190 3.4E-72 T 23-04-2016 DC74_RS38530 8b83711210e5d1da13c96605c7ea800b 190 Pfam PF01872 RibD C-terminal domain 2 182 1.5E-33 T 23-04-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 DC74_RS38530 8b83711210e5d1da13c96605c7ea800b 190 Gene3D G3DSA:3.40.430.10 4 188 2.2E-23 T 23-04-2016 IPR024072 Dihydrofolate reductase-like domain DC74_RS38530 8b83711210e5d1da13c96605c7ea800b 190 SUPERFAMILY SSF53597 4 188 1.7E-23 T 23-04-2016 IPR024072 Dihydrofolate reductase-like domain DC74_RS38530 8b83711210e5d1da13c96605c7ea800b 190 PANTHER PTHR38011 2 190 3.4E-72 T 23-04-2016 DC74_RS22445 c0f02b7d7fe444a587db672b1f136040 202 Pfam PF01227 GTP cyclohydrolase I 23 199 1.2E-76 T 23-04-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 DC74_RS22445 c0f02b7d7fe444a587db672b1f136040 202 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 18 200 41.48 T 23-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 DC74_RS22445 c0f02b7d7fe444a587db672b1f136040 202 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 23 199 2.0E-71 T 23-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 DC74_RS22445 c0f02b7d7fe444a587db672b1f136040 202 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 78 94 - T 23-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 DC74_RS22445 c0f02b7d7fe444a587db672b1f136040 202 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 128 138 - T 23-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 DC74_RS22445 c0f02b7d7fe444a587db672b1f136040 202 SUPERFAMILY SSF55620 16 199 7.34E-77 T 23-04-2016 DC74_RS22445 c0f02b7d7fe444a587db672b1f136040 202 Gene3D G3DSA:3.30.1130.10 71 199 9.8E-60 T 23-04-2016 DC74_RS22445 c0f02b7d7fe444a587db672b1f136040 202 PANTHER PTHR11109 18 199 3.2E-110 T 23-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 DC74_RS22445 c0f02b7d7fe444a587db672b1f136040 202 Gene3D G3DSA:1.10.286.10 17 68 1.6E-24 T 23-04-2016 DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 Pfam PF00196 Bacterial regulatory proteins, luxR family 872 924 2.0E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 Pfam PF13191 AAA ATPase domain 2 150 6.9E-16 T 23-04-2016 DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 ProSitePatterns PS00622 LuxR-type HTH domain signature. 887 914 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 Gene3D G3DSA:3.40.50.300 2 163 1.8E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 SUPERFAMILY SSF46894 862 925 7.82E-17 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 Gene3D G3DSA:1.25.40.10 367 406 2.0E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 Gene3D G3DSA:1.25.40.10 615 639 2.0E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 Gene3D G3DSA:1.25.40.10 683 838 2.0E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 SUPERFAMILY SSF52540 2 221 9.46E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 Gene3D G3DSA:1.10.10.10 871 926 2.2E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 SMART SM00421 870 927 2.3E-19 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 887 903 7.7E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 903 915 7.7E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04885 6a97e76154c80a1349dac7663ef74401 930 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 873 887 7.7E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS24855 d51c326813554d43f0703880762c6a5e 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 67 7.4E-13 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS24855 d51c326813554d43f0703880762c6a5e 240 SUPERFAMILY SSF64288 64 230 5.85E-19 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS24855 d51c326813554d43f0703880762c6a5e 240 SMART SM00866 93 233 0.001 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS24855 d51c326813554d43f0703880762c6a5e 240 SMART SM00345 10 68 1.1E-10 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS24855 d51c326813554d43f0703880762c6a5e 240 SUPERFAMILY SSF46785 3 80 2.1E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24855 d51c326813554d43f0703880762c6a5e 240 Pfam PF07702 UTRA domain 97 225 1.7E-13 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS24855 d51c326813554d43f0703880762c6a5e 240 Gene3D G3DSA:1.10.10.10 9 70 1.6E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24855 d51c326813554d43f0703880762c6a5e 240 Gene3D G3DSA:3.40.1410.10 71 229 1.4E-22 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS28315 f2637411967a44f2c972d3c990a633d0 421 Gene3D G3DSA:3.40.190.10 205 367 1.8E-40 T 23-04-2016 DC74_RS28315 f2637411967a44f2c972d3c990a633d0 421 PANTHER PTHR30222 77 410 1.7E-82 T 23-04-2016 DC74_RS28315 f2637411967a44f2c972d3c990a633d0 421 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 158 171 7.1E-9 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 DC74_RS28315 f2637411967a44f2c972d3c990a633d0 421 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 318 337 7.1E-9 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 DC74_RS28315 f2637411967a44f2c972d3c990a633d0 421 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 235 254 7.1E-9 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 DC74_RS28315 f2637411967a44f2c972d3c990a633d0 421 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 142 156 7.1E-9 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 DC74_RS28315 f2637411967a44f2c972d3c990a633d0 421 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 274 293 7.1E-9 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 DC74_RS28315 f2637411967a44f2c972d3c990a633d0 421 SUPERFAMILY SSF53850 80 416 2.43E-57 T 23-04-2016 DC74_RS28315 f2637411967a44f2c972d3c990a633d0 421 PANTHER PTHR30222:SF5 77 410 1.7E-82 T 23-04-2016 DC74_RS28315 f2637411967a44f2c972d3c990a633d0 421 Gene3D G3DSA:3.40.190.10 100 204 3.5E-6 T 23-04-2016 DC74_RS28315 f2637411967a44f2c972d3c990a633d0 421 Pfam PF13416 Bacterial extracellular solute-binding protein 105 372 8.9E-22 T 23-04-2016 DC74_RS18010 4ce3315f0170d6963788d46b063b35ed 170 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 20 95 7.0E-8 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS18010 4ce3315f0170d6963788d46b063b35ed 170 Gene3D G3DSA:2.30.110.10 11 111 4.1E-20 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS18010 4ce3315f0170d6963788d46b063b35ed 170 PANTHER PTHR35176:SF1 1 147 1.7E-32 T 23-04-2016 DC74_RS18010 4ce3315f0170d6963788d46b063b35ed 170 PANTHER PTHR35176 1 147 1.7E-32 T 23-04-2016 DC74_RS18010 4ce3315f0170d6963788d46b063b35ed 170 SUPERFAMILY SSF50475 12 106 5.05E-19 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS07145 b1443d21b0e7e087be111f1f834a3cdc 959 Pfam PF00664 ABC transporter transmembrane region 417 680 2.5E-18 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS07145 b1443d21b0e7e087be111f1f834a3cdc 959 Gene3D G3DSA:3.40.50.300 724 947 3.1E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07145 b1443d21b0e7e087be111f1f834a3cdc 959 SMART SM00382 750 926 1.7E-19 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS07145 b1443d21b0e7e087be111f1f834a3cdc 959 Pfam PF00005 ABC transporter 741 888 1.4E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS07145 b1443d21b0e7e087be111f1f834a3cdc 959 SUPERFAMILY SSF52540 719 957 2.46E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07145 b1443d21b0e7e087be111f1f834a3cdc 959 PANTHER PTHR24221 209 958 3.2E-201 T 23-04-2016 DC74_RS07145 b1443d21b0e7e087be111f1f834a3cdc 959 SUPERFAMILY SSF90123 398 709 2.22E-37 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS07145 b1443d21b0e7e087be111f1f834a3cdc 959 PANTHER PTHR24221:SF161 209 958 3.2E-201 T 23-04-2016 DC74_RS07145 b1443d21b0e7e087be111f1f834a3cdc 959 Gene3D G3DSA:1.20.1560.10 398 708 3.4E-33 T 23-04-2016 DC74_RS07145 b1443d21b0e7e087be111f1f834a3cdc 959 TIGRFAM TIGR03797 NHLM_micro_ABC2: NHLM bacteriocin system ABC transporter, ATP-binding protein 278 958 4.7E-266 T 23-04-2016 IPR022515 NHPM bacteriocin system ABC transporter, ATP-binding protein DC74_RS07145 b1443d21b0e7e087be111f1f834a3cdc 959 ProSitePatterns PS00211 ABC transporters family signature. 860 874 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS13845 6a80114a515780f70519cf3de01cc747 178 Gene3D G3DSA:1.10.10.10 2 120 2.2E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13845 6a80114a515780f70519cf3de01cc747 178 SUPERFAMILY SSF46785 2 122 6.94E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13845 6a80114a515780f70519cf3de01cc747 178 PANTHER PTHR33164 1 130 2.9E-14 T 23-04-2016 DC74_RS13845 6a80114a515780f70519cf3de01cc747 178 Pfam PF12802 MarR family 12 70 9.9E-13 T 23-04-2016 DC74_RS13845 6a80114a515780f70519cf3de01cc747 178 SMART SM00347 6 106 4.2E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS39055 9c5d68f4a75eab71c443f3a0349ef9fe 540 SUPERFAMILY SSF56601 189 534 1.5E-51 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS39055 9c5d68f4a75eab71c443f3a0349ef9fe 540 Pfam PF00144 Beta-lactamase 192 528 1.4E-49 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS39055 9c5d68f4a75eab71c443f3a0349ef9fe 540 Gene3D G3DSA:3.40.710.10 176 535 1.3E-50 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS39055 9c5d68f4a75eab71c443f3a0349ef9fe 540 PANTHER PTHR22935 84 539 2.3E-30 T 23-04-2016 DC74_RS33885 5c5b2c489e0b7705d7570a936ca1bbc7 322 PANTHER PTHR40111 1 321 5.8E-84 T 23-04-2016 DC74_RS33885 5c5b2c489e0b7705d7570a936ca1bbc7 322 PANTHER PTHR40111:SF1 1 321 5.8E-84 T 23-04-2016 DC74_RS33885 5c5b2c489e0b7705d7570a936ca1bbc7 322 Pfam PF05448 Acetyl xylan esterase (AXE1) 2 318 1.3E-99 T 23-04-2016 IPR008391 Acetyl xylan esterase DC74_RS33885 5c5b2c489e0b7705d7570a936ca1bbc7 322 SUPERFAMILY SSF53474 5 297 1.5E-29 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS33885 5c5b2c489e0b7705d7570a936ca1bbc7 322 Gene3D G3DSA:3.40.50.1820 2 321 1.6E-86 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 PANTHER PTHR13789:SF90 1 335 1.4E-88 T 23-04-2016 DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 SUPERFAMILY SSF51905 1 171 1.95E-65 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 SUPERFAMILY SSF51905 261 339 1.95E-65 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 6.4E-36 T 23-04-2016 DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 6.4E-36 T 23-04-2016 DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 305 6.4E-36 T 23-04-2016 DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 6.4E-36 T 23-04-2016 DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 Pfam PF01494 FAD binding domain 2 332 6.1E-76 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 Gene3D G3DSA:3.30.9.10 237 283 5.4E-5 T 23-04-2016 DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 Gene3D G3DSA:3.50.50.60 284 311 7.3E-60 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 Gene3D G3DSA:3.50.50.60 2 174 7.3E-60 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 SUPERFAMILY SSF52833 363 458 2.94E-6 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS06325 1a6b25c39ceb5040878ce3563749f6b8 461 PANTHER PTHR13789 1 335 1.4E-88 T 23-04-2016 DC74_RS39515 5e2250d34f56ee0e5e862e123162b207 221 PANTHER PTHR30383 10 221 2.9E-25 T 23-04-2016 DC74_RS39515 5e2250d34f56ee0e5e862e123162b207 221 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 13 211 1.4E-20 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS39515 5e2250d34f56ee0e5e862e123162b207 221 SUPERFAMILY SSF52266 7 220 7.66E-36 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS39515 5e2250d34f56ee0e5e862e123162b207 221 Gene3D G3DSA:3.40.50.1110 10 218 2.9E-33 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS05515 3a44f8a37b2afe26dd78c6bdf495bfd6 315 PANTHER PTHR22916 1 281 1.2E-178 T 23-04-2016 DC74_RS05515 3a44f8a37b2afe26dd78c6bdf495bfd6 315 SUPERFAMILY SSF53448 5 223 6.28E-42 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS05515 3a44f8a37b2afe26dd78c6bdf495bfd6 315 Gene3D G3DSA:3.90.550.10 5 219 2.8E-41 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS05515 3a44f8a37b2afe26dd78c6bdf495bfd6 315 PANTHER PTHR22916:SF12 1 281 1.2E-178 T 23-04-2016 DC74_RS05515 3a44f8a37b2afe26dd78c6bdf495bfd6 315 Pfam PF00535 Glycosyl transferase family 2 8 121 1.7E-24 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS29290 158636a468e5e5fd9a70b9c2d3fdc56b 151 SUPERFAMILY SSF46785 6 143 4.6E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29290 158636a468e5e5fd9a70b9c2d3fdc56b 151 PANTHER PTHR33164 5 151 3.5E-13 T 23-04-2016 DC74_RS29290 158636a468e5e5fd9a70b9c2d3fdc56b 151 SMART SM00347 27 127 0.0019 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS29290 158636a468e5e5fd9a70b9c2d3fdc56b 151 Pfam PF12802 MarR family 36 91 1.4E-9 T 23-04-2016 DC74_RS29290 158636a468e5e5fd9a70b9c2d3fdc56b 151 Gene3D G3DSA:1.10.10.10 5 139 1.8E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38795 a148c51c05a6a6e9ad63d50cf5ea1449 406 PIRSF PIRSF005962 1 397 7.7E-107 T 23-04-2016 IPR017439 Amidohydrolase GO:0016787 DC74_RS38795 a148c51c05a6a6e9ad63d50cf5ea1449 406 PANTHER PTHR11014 1 398 4.4E-120 T 23-04-2016 DC74_RS38795 a148c51c05a6a6e9ad63d50cf5ea1449 406 PANTHER PTHR11014:SF63 1 398 4.4E-120 T 23-04-2016 DC74_RS38795 a148c51c05a6a6e9ad63d50cf5ea1449 406 Pfam PF01546 Peptidase family M20/M25/M40 72 370 1.5E-30 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS38795 a148c51c05a6a6e9ad63d50cf5ea1449 406 SUPERFAMILY SSF53187 302 394 1.65E-75 T 23-04-2016 DC74_RS38795 a148c51c05a6a6e9ad63d50cf5ea1449 406 SUPERFAMILY SSF53187 3 201 1.65E-75 T 23-04-2016 DC74_RS38795 a148c51c05a6a6e9ad63d50cf5ea1449 406 Pfam PF07687 Peptidase dimerisation domain 191 284 3.2E-11 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS38795 a148c51c05a6a6e9ad63d50cf5ea1449 406 Gene3D G3DSA:3.30.70.360 186 301 1.1E-36 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS38795 a148c51c05a6a6e9ad63d50cf5ea1449 406 Gene3D G3DSA:3.40.630.10 302 395 4.8E-89 T 23-04-2016 DC74_RS38795 a148c51c05a6a6e9ad63d50cf5ea1449 406 Gene3D G3DSA:3.40.630.10 4 182 4.8E-89 T 23-04-2016 DC74_RS38795 a148c51c05a6a6e9ad63d50cf5ea1449 406 SUPERFAMILY SSF55031 187 300 1.2E-29 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS38795 a148c51c05a6a6e9ad63d50cf5ea1449 406 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 379 2.5E-91 T 23-04-2016 IPR017439 Amidohydrolase GO:0016787 DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 190 1.6E-4 T 23-04-2016 DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.5E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 2.5E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.5E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PANTHER PTHR24322 159 190 7.0E-45 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PANTHER PTHR24322 16 143 7.0E-45 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 SUPERFAMILY SSF51735 10 260 4.63E-78 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PANTHER PTHR24322:SF429 159 190 7.0E-45 T 23-04-2016 DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PANTHER PTHR24322:SF429 16 143 7.0E-45 T 23-04-2016 DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 Gene3D G3DSA:3.40.50.720 6 260 2.0E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 7.3E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 7.3E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 7.3E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 7.3E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 7.3E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 7.3E-38 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS04745 0aa76f23d08ec5106b91cd5365da52c5 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 260 1.5E-58 T 23-04-2016 DC74_RS02750 08c41261257332d19930d4e749ea2fc8 439 PANTHER PTHR11751:SF410 84 430 4.4E-105 T 23-04-2016 DC74_RS02750 08c41261257332d19930d4e749ea2fc8 439 PANTHER PTHR11751:SF410 14 66 4.4E-105 T 23-04-2016 DC74_RS02750 08c41261257332d19930d4e749ea2fc8 439 Gene3D G3DSA:3.90.1150.10 269 433 2.7E-29 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS02750 08c41261257332d19930d4e749ea2fc8 439 SUPERFAMILY SSF53383 30 435 2.28E-74 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS02750 08c41261257332d19930d4e749ea2fc8 439 Gene3D G3DSA:3.40.640.10 81 268 1.3E-45 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS02750 08c41261257332d19930d4e749ea2fc8 439 Pfam PF00155 Aminotransferase class I and II 88 430 2.1E-28 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS02750 08c41261257332d19930d4e749ea2fc8 439 PANTHER PTHR11751 84 430 4.4E-105 T 23-04-2016 DC74_RS02750 08c41261257332d19930d4e749ea2fc8 439 PANTHER PTHR11751 14 66 4.4E-105 T 23-04-2016 DC74_RS09085 af2fbe68315031b5d935f2009afc8d51 377 PANTHER PTHR37539 49 315 3.0E-18 T 23-04-2016 DC74_RS09085 af2fbe68315031b5d935f2009afc8d51 377 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 93 309 3.5E-19 T 23-04-2016 IPR018713 Domain of unknown function DUF2236 DC74_RS20365 7a33bb9431eae3236ee1527f59566afc 138 Gene3D G3DSA:2.30.110.10 8 122 6.0E-13 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS20365 7a33bb9431eae3236ee1527f59566afc 138 SUPERFAMILY SSF50475 7 122 8.76E-10 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS20365 7a33bb9431eae3236ee1527f59566afc 138 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 8 121 1.8E-14 T 23-04-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related DC74_RS30410 946e1009c8493dffca599ced44eb7494 287 Pfam PF03771 Domain of unknown function (DUF317) 64 120 1.3E-15 T 23-04-2016 IPR005523 Domain of unknown function DUF317 DC74_RS06920 30939c8ba0d00c299de05e62e715ea79 238 PANTHER PTHR23200 34 178 3.1E-25 T 23-04-2016 DC74_RS06920 30939c8ba0d00c299de05e62e715ea79 238 SUPERFAMILY SSF56281 10 233 9.7E-32 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS06920 30939c8ba0d00c299de05e62e715ea79 238 Gene3D G3DSA:3.60.15.10 28 228 8.5E-33 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS06920 30939c8ba0d00c299de05e62e715ea79 238 Pfam PF00753 Metallo-beta-lactamase superfamily 33 180 1.8E-22 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS06920 30939c8ba0d00c299de05e62e715ea79 238 SMART SM00849 34 227 7.1E-16 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS25375 76791235e40280f046167ddc892a4a27 491 PIRSF PIRSF002746 24 491 6.7E-160 T 23-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 DC74_RS25375 76791235e40280f046167ddc892a4a27 491 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 30 491 1.2E-112 T 23-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 DC74_RS25375 76791235e40280f046167ddc892a4a27 491 PANTHER PTHR30354:SF2 25 491 6.2E-235 T 23-04-2016 DC74_RS25375 76791235e40280f046167ddc892a4a27 491 Pfam PF02447 GntP family permease 30 489 3.5E-124 T 23-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 DC74_RS25375 76791235e40280f046167ddc892a4a27 491 PANTHER PTHR30354 25 491 6.2E-235 T 23-04-2016 DC74_RS30270 c3a5e6a5e82e2047c3d76a86037a0913 237 PANTHER PTHR30055:SF93 12 235 2.1E-40 T 23-04-2016 DC74_RS30270 c3a5e6a5e82e2047c3d76a86037a0913 237 PANTHER PTHR30055 12 235 2.1E-40 T 23-04-2016 DC74_RS30270 c3a5e6a5e82e2047c3d76a86037a0913 237 SUPERFAMILY SSF48498 91 236 6.45E-22 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS30270 c3a5e6a5e82e2047c3d76a86037a0913 237 Gene3D G3DSA:1.10.357.10 15 236 8.1E-54 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS30270 c3a5e6a5e82e2047c3d76a86037a0913 237 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 73 3.2E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS30270 c3a5e6a5e82e2047c3d76a86037a0913 237 SUPERFAMILY SSF46689 20 82 3.49E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS30270 c3a5e6a5e82e2047c3d76a86037a0913 237 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 92 234 1.4E-16 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS26705 ab84016ae92eb1df8d773dfa08b3ec53 307 Pfam PF00805 Pentapeptide repeats (8 copies) 221 256 1.4E-11 T 23-04-2016 IPR001646 Pentapeptide repeat DC74_RS26705 ab84016ae92eb1df8d773dfa08b3ec53 307 PANTHER PTHR14136 22 146 3.1E-43 T 23-04-2016 DC74_RS26705 ab84016ae92eb1df8d773dfa08b3ec53 307 PANTHER PTHR14136:SF0 22 146 3.1E-43 T 23-04-2016 DC74_RS26705 ab84016ae92eb1df8d773dfa08b3ec53 307 PANTHER PTHR14136 167 280 3.1E-43 T 23-04-2016 DC74_RS26705 ab84016ae92eb1df8d773dfa08b3ec53 307 PANTHER PTHR14136:SF0 167 280 3.1E-43 T 23-04-2016 DC74_RS26705 ab84016ae92eb1df8d773dfa08b3ec53 307 SUPERFAMILY SSF141571 71 107 5.1E-23 T 23-04-2016 DC74_RS26705 ab84016ae92eb1df8d773dfa08b3ec53 307 SUPERFAMILY SSF141571 198 299 5.1E-23 T 23-04-2016 DC74_RS32240 552baa659da07138aef40a7c2e60006d 221 SUPERFAMILY SSF52172 1 173 5.55E-34 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS32240 552baa659da07138aef40a7c2e60006d 221 Gene3D G3DSA:3.40.50.2300 1 120 4.5E-31 T 23-04-2016 DC74_RS32240 552baa659da07138aef40a7c2e60006d 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 1.9E-21 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS32240 552baa659da07138aef40a7c2e60006d 221 SMART SM00448 1 112 6.3E-33 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS32240 552baa659da07138aef40a7c2e60006d 221 SMART SM00862 145 217 8.5E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS32240 552baa659da07138aef40a7c2e60006d 221 PANTHER PTHR26402 1 220 3.6E-78 T 23-04-2016 DC74_RS32240 552baa659da07138aef40a7c2e60006d 221 PANTHER PTHR26402:SF553 1 220 3.6E-78 T 23-04-2016 DC74_RS32240 552baa659da07138aef40a7c2e60006d 221 Gene3D G3DSA:1.10.10.10 125 217 1.3E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32240 552baa659da07138aef40a7c2e60006d 221 Pfam PF00072 Response regulator receiver domain 3 112 5.0E-22 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS19070 4a84a71e9ce5f5fe78965f35a7a9a57f 190 Gene3D G3DSA:3.40.50.700 24 149 7.4E-34 T 23-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 DC74_RS19070 4a84a71e9ce5f5fe78965f35a7a9a57f 190 PANTHER PTHR11995:SF2 4 190 1.6E-88 T 23-04-2016 DC74_RS19070 4a84a71e9ce5f5fe78965f35a7a9a57f 190 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 1.2E-24 T 23-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 DC74_RS19070 4a84a71e9ce5f5fe78965f35a7a9a57f 190 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 151 4.3E-70 T 23-04-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 DC74_RS19070 4a84a71e9ce5f5fe78965f35a7a9a57f 190 SUPERFAMILY SSF56770 9 153 1.1E-65 T 23-04-2016 DC74_RS19070 4a84a71e9ce5f5fe78965f35a7a9a57f 190 PANTHER PTHR11995 4 190 1.6E-88 T 23-04-2016 DC74_RS19070 4a84a71e9ce5f5fe78965f35a7a9a57f 190 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 23-04-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 DC74_RS19070 4a84a71e9ce5f5fe78965f35a7a9a57f 190 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.488 T 23-04-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 DC74_RS39715 97b9624b61285747f7459c180ca045b9 301 Gene3D G3DSA:1.10.10.10 1 79 4.1E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39715 97b9624b61285747f7459c180ca045b9 301 SUPERFAMILY SSF46785 1 109 5.54E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39715 97b9624b61285747f7459c180ca045b9 301 PANTHER PTHR30346 1 301 4.2E-49 T 23-04-2016 DC74_RS39715 97b9624b61285747f7459c180ca045b9 301 Gene3D G3DSA:3.40.190.10 178 265 3.0E-15 T 23-04-2016 DC74_RS39715 97b9624b61285747f7459c180ca045b9 301 Gene3D G3DSA:3.40.190.10 92 177 1.4E-13 T 23-04-2016 DC74_RS39715 97b9624b61285747f7459c180ca045b9 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS39715 97b9624b61285747f7459c180ca045b9 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS39715 97b9624b61285747f7459c180ca045b9 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS39715 97b9624b61285747f7459c180ca045b9 301 SUPERFAMILY SSF53850 88 297 8.69E-29 T 23-04-2016 DC74_RS39715 97b9624b61285747f7459c180ca045b9 301 Pfam PF03466 LysR substrate binding domain 88 293 1.8E-29 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS39715 97b9624b61285747f7459c180ca045b9 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.2E-16 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS38600 cd8e211f07011bef554940c905e8cea5 291 SUPERFAMILY SSF63829 47 273 1.8E-38 T 23-04-2016 DC74_RS38600 cd8e211f07011bef554940c905e8cea5 291 PIRSF PIRSF026412 5 290 3.0E-104 T 23-04-2016 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 DC74_RS38600 cd8e211f07011bef554940c905e8cea5 291 PANTHER PTHR40274 2 289 2.4E-96 T 23-04-2016 DC74_RS38600 cd8e211f07011bef554940c905e8cea5 291 Gene3D G3DSA:2.120.10.30 112 253 5.7E-21 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS38600 cd8e211f07011bef554940c905e8cea5 291 Gene3D G3DSA:2.120.10.30 4 111 3.2E-14 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS38600 cd8e211f07011bef554940c905e8cea5 291 Hamap MF_01282 Virginiamycin B lyase [vgb]. 7 288 43.865 T 23-04-2016 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 DC74_RS38600 cd8e211f07011bef554940c905e8cea5 291 PANTHER PTHR40274:SF2 2 289 2.4E-96 T 23-04-2016 DC74_RS23045 680bc4dc81ac42c3ee47048b681b55f0 315 Gene3D G3DSA:3.40.50.720 19 220 1.3E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS23045 680bc4dc81ac42c3ee47048b681b55f0 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 1.3E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS23045 680bc4dc81ac42c3ee47048b681b55f0 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 1.3E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS23045 680bc4dc81ac42c3ee47048b681b55f0 315 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 1.3E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS23045 680bc4dc81ac42c3ee47048b681b55f0 315 PANTHER PTHR24320 9 307 1.9E-87 T 23-04-2016 DC74_RS23045 680bc4dc81ac42c3ee47048b681b55f0 315 SUPERFAMILY SSF51735 13 243 1.9E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS23045 680bc4dc81ac42c3ee47048b681b55f0 315 PANTHER PTHR24320:SF45 9 307 1.9E-87 T 23-04-2016 DC74_RS23045 680bc4dc81ac42c3ee47048b681b55f0 315 Pfam PF00106 short chain dehydrogenase 22 161 3.5E-21 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS23045 680bc4dc81ac42c3ee47048b681b55f0 315 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 21 183 0.0046 T 23-04-2016 DC74_RS17745 28b3130564fdf8c22ab53a36d495f545 278 SMART SM00530 19 74 1.4E-7 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS17745 28b3130564fdf8c22ab53a36d495f545 278 Gene3D G3DSA:1.10.260.40 12 68 4.8E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS17745 28b3130564fdf8c22ab53a36d495f545 278 PANTHER PTHR10245:SF7 1 278 1.1E-26 T 23-04-2016 DC74_RS17745 28b3130564fdf8c22ab53a36d495f545 278 PANTHER PTHR10245 1 278 1.1E-26 T 23-04-2016 DC74_RS17745 28b3130564fdf8c22ab53a36d495f545 278 SUPERFAMILY SSF47413 16 63 3.1E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS17745 28b3130564fdf8c22ab53a36d495f545 278 Pfam PF13560 Helix-turn-helix domain 16 72 4.9E-12 T 23-04-2016 DC74_RS34940 701d3ce8139469c2c9325b299baf8e14 431 SUPERFAMILY SSF53850 23 429 4.19E-61 T 23-04-2016 DC74_RS34940 701d3ce8139469c2c9325b299baf8e14 431 Pfam PF01547 Bacterial extracellular solute-binding protein 58 337 1.7E-33 T 23-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 DC74_RS34940 701d3ce8139469c2c9325b299baf8e14 431 Gene3D G3DSA:3.40.190.10 39 173 6.1E-13 T 23-04-2016 DC74_RS34940 701d3ce8139469c2c9325b299baf8e14 431 Gene3D G3DSA:3.40.190.10 174 359 1.3E-30 T 23-04-2016 DC74_RS34940 701d3ce8139469c2c9325b299baf8e14 431 PANTHER PTHR30061:SF24 3 429 6.7E-93 T 23-04-2016 DC74_RS34940 701d3ce8139469c2c9325b299baf8e14 431 PANTHER PTHR30061 3 429 6.7E-93 T 23-04-2016 DC74_RS28675 153d5789f511db72495482aa368cf879 219 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 25 194 6.1E-38 T 23-04-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 DC74_RS28675 153d5789f511db72495482aa368cf879 219 Pfam PF01066 CDP-alcohol phosphatidyltransferase 25 95 3.2E-16 T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS28675 153d5789f511db72495482aa368cf879 219 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 73 95 - T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS28675 153d5789f511db72495482aa368cf879 219 PANTHER PTHR14269 23 192 1.6E-38 T 23-04-2016 DC74_RS31765 6fed3d9dd5c18b9519ba93aa4bd00df7 321 Gene3D G3DSA:3.20.20.60 8 253 1.7E-79 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS31765 6fed3d9dd5c18b9519ba93aa4bd00df7 321 PANTHER PTHR32308:SF2 7 318 3.3E-186 T 23-04-2016 DC74_RS31765 6fed3d9dd5c18b9519ba93aa4bd00df7 321 PANTHER PTHR32308 7 318 3.3E-186 T 23-04-2016 IPR011206 Citrate lyase beta subunit-like DC74_RS31765 6fed3d9dd5c18b9519ba93aa4bd00df7 321 PIRSF PIRSF015582 1 320 2.0E-91 T 23-04-2016 IPR011206 Citrate lyase beta subunit-like DC74_RS31765 6fed3d9dd5c18b9519ba93aa4bd00df7 321 SUPERFAMILY SSF51621 8 253 8.79E-67 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS31765 6fed3d9dd5c18b9519ba93aa4bd00df7 321 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 12 242 1.8E-46 T 23-04-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 DC74_RS15395 3782398d644abb2882e9c72a6f21eb7d 473 PANTHER PTHR11785:SF386 27 473 1.1E-221 T 23-04-2016 DC74_RS15395 3782398d644abb2882e9c72a6f21eb7d 473 Pfam PF00324 Amino acid permease 36 440 3.6E-100 T 23-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 DC74_RS15395 3782398d644abb2882e9c72a6f21eb7d 473 ProSitePatterns PS00218 Amino acid permeases signature. 61 91 - T 23-04-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 DC74_RS15395 3782398d644abb2882e9c72a6f21eb7d 473 PIRSF PIRSF006060 6 470 8.7E-64 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS15395 3782398d644abb2882e9c72a6f21eb7d 473 PANTHER PTHR11785 27 473 1.1E-221 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS08190 619426a81003f192c5c1cbd38b968e79 279 Gene3D G3DSA:1.10.3720.10 6 266 2.7E-38 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS08190 619426a81003f192c5c1cbd38b968e79 279 PANTHER PTHR30193 6 272 4.8E-61 T 23-04-2016 DC74_RS08190 619426a81003f192c5c1cbd38b968e79 279 SUPERFAMILY SSF161098 13 272 1.96E-42 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS08190 619426a81003f192c5c1cbd38b968e79 279 PANTHER PTHR30193:SF5 6 272 4.8E-61 T 23-04-2016 DC74_RS08190 619426a81003f192c5c1cbd38b968e79 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 263 3.9E-14 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS02705 c429800e5ace5c23db2de10d1d80af9e 143 SUPERFAMILY SSF46955 4 51 4.58E-11 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS02705 c429800e5ace5c23db2de10d1d80af9e 143 Pfam PF12728 Helix-turn-helix domain 5 50 7.1E-17 T 23-04-2016 DC74_RS02705 c429800e5ace5c23db2de10d1d80af9e 143 Gene3D G3DSA:1.10.1660.10 3 42 2.3E-5 T 23-04-2016 DC74_RS02705 c429800e5ace5c23db2de10d1d80af9e 143 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 50 5.6E-15 T 23-04-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 DC74_RS32390 bd1901755fecf189901465b28fc2a77c 394 Pfam PF06722 Protein of unknown function (DUF1205) 177 275 7.1E-14 T 23-04-2016 IPR010610 Domain of unknown function DUF1205 DC74_RS32390 bd1901755fecf189901465b28fc2a77c 394 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 289 366 2.2E-4 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS32390 bd1901755fecf189901465b28fc2a77c 394 Gene3D G3DSA:3.40.50.2000 1 222 1.3E-22 T 23-04-2016 DC74_RS32390 bd1901755fecf189901465b28fc2a77c 394 Gene3D G3DSA:3.40.50.2000 223 372 6.1E-25 T 23-04-2016 DC74_RS32390 bd1901755fecf189901465b28fc2a77c 394 SUPERFAMILY SSF53756 1 391 5.14E-73 T 23-04-2016 DC74_RS13195 70b06d892bbe1cd6abaa803c6d62a218 81 Pfam PF04149 Domain of unknown function (DUF397) 29 69 8.9E-9 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS03860 86ddf95c8950fb3fd15e356edd74c162 146 Pfam PF00583 Acetyltransferase (GNAT) family 50 125 7.1E-11 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS03860 86ddf95c8950fb3fd15e356edd74c162 146 SUPERFAMILY SSF55729 8 145 1.03E-23 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS03860 86ddf95c8950fb3fd15e356edd74c162 146 Gene3D G3DSA:3.40.630.30 8 130 2.5E-20 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS03860 86ddf95c8950fb3fd15e356edd74c162 146 PANTHER PTHR23091 8 146 2.1E-12 T 23-04-2016 DC74_RS40345 2e0b6a0fc1aa4e6d9c094604a6a19483 394 PANTHER PTHR33375 4 174 1.5E-49 T 23-04-2016 DC74_RS40345 2e0b6a0fc1aa4e6d9c094604a6a19483 394 PANTHER PTHR33375 195 245 1.5E-49 T 23-04-2016 DC74_RS40345 2e0b6a0fc1aa4e6d9c094604a6a19483 394 Gene3D G3DSA:3.90.1530.10 5 101 7.8E-31 T 23-04-2016 DC74_RS40345 2e0b6a0fc1aa4e6d9c094604a6a19483 394 Pfam PF02195 ParB-like nuclease domain 6 95 2.2E-22 T 23-04-2016 IPR003115 ParB/Sulfiredoxin DC74_RS40345 2e0b6a0fc1aa4e6d9c094604a6a19483 394 SMART SM00470 3 96 3.5E-28 T 23-04-2016 IPR003115 ParB/Sulfiredoxin DC74_RS40345 2e0b6a0fc1aa4e6d9c094604a6a19483 394 SUPERFAMILY SSF110849 7 130 7.67E-26 T 23-04-2016 IPR003115 ParB/Sulfiredoxin DC74_RS40345 2e0b6a0fc1aa4e6d9c094604a6a19483 394 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 5 159 3.2E-38 T 23-04-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 DC74_RS27080 fdd417773632661db696b198493201d6 190 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 8 182 2.3E-47 T 23-04-2016 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 DC74_RS27080 fdd417773632661db696b198493201d6 190 PANTHER PTHR12213 1 185 4.3E-66 T 23-04-2016 DC74_RS27080 fdd417773632661db696b198493201d6 190 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 13 184 1.0E-71 T 23-04-2016 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 DC74_RS27080 fdd417773632661db696b198493201d6 190 SUPERFAMILY SSF89028 6 185 2.16E-54 T 23-04-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 DC74_RS27080 fdd417773632661db696b198493201d6 190 Pfam PF01923 Cobalamin adenosyltransferase 7 174 6.9E-53 T 23-04-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 DC74_RS27080 fdd417773632661db696b198493201d6 190 Gene3D G3DSA:1.20.1200.10 16 188 8.8E-55 T 23-04-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 DC74_RS11015 2afa747e3d8efbfa535d8c085ce84488 120 PIRSF PIRSF005965 1 120 8.9E-42 T 23-04-2016 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS11015 2afa747e3d8efbfa535d8c085ce84488 120 PANTHER PTHR21164:SF0 1 120 2.3E-49 T 23-04-2016 DC74_RS11015 2afa747e3d8efbfa535d8c085ce84488 120 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 9 118 1.0E-47 T 23-04-2016 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS11015 2afa747e3d8efbfa535d8c085ce84488 120 SUPERFAMILY SSF55298 2 118 6.2E-40 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS11015 2afa747e3d8efbfa535d8c085ce84488 120 Gene3D G3DSA:3.30.1330.40 3 119 3.4E-44 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS11015 2afa747e3d8efbfa535d8c085ce84488 120 PANTHER PTHR21164 1 120 2.3E-49 T 23-04-2016 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS11015 2afa747e3d8efbfa535d8c085ce84488 120 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 3 118 1.8E-48 T 23-04-2016 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS11015 2afa747e3d8efbfa535d8c085ce84488 120 Pfam PF07736 Chorismate mutase type I 3 118 3.5E-41 T 23-04-2016 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 DC74_RS09490 6c4e6ecb0b911c6ff32f66db04144a70 146 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 5 133 1.0E-40 T 23-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 DC74_RS09490 6c4e6ecb0b911c6ff32f66db04144a70 146 Gene3D G3DSA:3.40.50.9100 4 144 7.3E-55 T 23-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 DC74_RS09490 6c4e6ecb0b911c6ff32f66db04144a70 146 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 143 1.9E-52 T 23-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 DC74_RS09490 6c4e6ecb0b911c6ff32f66db04144a70 146 ProSitePatterns PS01029 Dehydroquinase class II signature. 8 25 - T 23-04-2016 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 DC74_RS09490 6c4e6ecb0b911c6ff32f66db04144a70 146 Pfam PF01220 Dehydroquinase class II 4 140 5.2E-50 T 23-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 DC74_RS09490 6c4e6ecb0b911c6ff32f66db04144a70 146 SUPERFAMILY SSF52304 4 144 3.53E-52 T 23-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 DC74_RS09490 6c4e6ecb0b911c6ff32f66db04144a70 146 PANTHER PTHR21272 1 145 8.8E-68 T 23-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 DC74_RS09490 6c4e6ecb0b911c6ff32f66db04144a70 146 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 146 58.711 T 23-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 DC74_RS09490 6c4e6ecb0b911c6ff32f66db04144a70 146 PIRSF PIRSF001399 1 146 7.0E-54 T 23-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 DC74_RS15355 aabad01a43b3a6efac7ef674966c5b27 413 Pfam PF00999 Sodium/hydrogen exchanger family 7 363 1.9E-58 T 23-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 DC74_RS15355 aabad01a43b3a6efac7ef674966c5b27 413 PANTHER PTHR16254 1 375 2.3E-171 T 23-04-2016 DC74_RS15355 aabad01a43b3a6efac7ef674966c5b27 413 PANTHER PTHR16254:SF5 1 375 2.3E-171 T 23-04-2016 DC74_RS34165 f90da835bdd6a985ed4c3c79e5e5ade1 248 PANTHER PTHR30346:SF0 5 197 4.3E-44 T 23-04-2016 DC74_RS34165 f90da835bdd6a985ed4c3c79e5e5ade1 248 Pfam PF03466 LysR substrate binding domain 5 176 1.7E-23 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS34165 f90da835bdd6a985ed4c3c79e5e5ade1 248 Gene3D G3DSA:3.40.190.10 72 150 2.9E-8 T 23-04-2016 DC74_RS34165 f90da835bdd6a985ed4c3c79e5e5ade1 248 Gene3D G3DSA:3.40.190.10 6 71 5.5E-15 T 23-04-2016 DC74_RS34165 f90da835bdd6a985ed4c3c79e5e5ade1 248 PANTHER PTHR30346 5 197 4.3E-44 T 23-04-2016 DC74_RS34165 f90da835bdd6a985ed4c3c79e5e5ade1 248 SUPERFAMILY SSF53850 5 178 2.24E-23 T 23-04-2016 DC74_RS20185 9820d1fef14381798d5a328b99270d71 433 PANTHER PTHR14741 190 364 2.9E-44 T 23-04-2016 DC74_RS20185 9820d1fef14381798d5a328b99270d71 433 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 240 361 5.1E-32 T 23-04-2016 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 DC74_RS20185 9820d1fef14381798d5a328b99270d71 433 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 198 1.9E-23 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS20185 9820d1fef14381798d5a328b99270d71 433 Gene3D G3DSA:3.30.950.10 117 217 1.8E-27 T 23-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 DC74_RS20185 9820d1fef14381798d5a328b99270d71 433 PIRSF PIRSF036428 4 411 1.4E-142 T 23-04-2016 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00148 DC74_RS20185 9820d1fef14381798d5a328b99270d71 433 PANTHER PTHR14741:SF34 190 364 2.9E-44 T 23-04-2016 DC74_RS20185 9820d1fef14381798d5a328b99270d71 433 SUPERFAMILY SSF53790 7 214 1.2E-39 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS20185 9820d1fef14381798d5a328b99270d71 433 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 9 202 1.4E-50 T 23-04-2016 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 DC74_RS20185 9820d1fef14381798d5a328b99270d71 433 Gene3D G3DSA:3.40.50.150 231 401 6.9E-20 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS20185 9820d1fef14381798d5a328b99270d71 433 Gene3D G3DSA:3.40.1010.10 7 116 8.3E-28 T 23-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 DC74_RS20185 9820d1fef14381798d5a328b99270d71 433 SUPERFAMILY SSF53335 213 405 2.76E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS08570 fb5c55c0f4bb1069f47fc8e290840a66 135 Gene3D G3DSA:2.120.10.30 2 123 1.4E-5 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS08570 fb5c55c0f4bb1069f47fc8e290840a66 135 SUPERFAMILY SSF50998 1 124 8.63E-8 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 SMART SM00926 47 109 9.0E-6 T 23-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 761 778 - T 23-04-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 Gene3D G3DSA:2.40.40.20 1042 1212 7.4E-38 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 Pfam PF01568 Molydopterin dinucleotide binding domain 1073 1182 3.9E-21 T 23-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 PANTHER PTHR11615:SF35 683 820 0.0 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 SUPERFAMILY SSF53706 9 1053 0.0 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 PANTHER PTHR11615 38 417 0.0 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 PANTHER PTHR11615 981 1214 0.0 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 Gene3D G3DSA:3.40.50.740 147 218 1.8E-7 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 52 70 - T 23-04-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 PANTHER PTHR11615:SF35 38 417 0.0 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 PANTHER PTHR11615:SF35 981 1214 0.0 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 PANTHER PTHR11615 836 862 0.0 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 Pfam PF00384 Molybdopterin oxidoreductase 112 816 6.5E-130 T 23-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 Gene3D G3DSA:3.90.55.10 765 820 2.8E-6 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 PANTHER PTHR11615 683 820 0.0 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 Gene3D G3DSA:3.40.50.740 579 764 3.4E-50 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 Gene3D G3DSA:3.40.228.10 478 578 2.5E-82 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 Gene3D G3DSA:3.40.228.10 225 340 2.5E-82 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 37 1213 0.0 T 23-04-2016 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 PANTHER PTHR11615:SF35 836 862 0.0 T 23-04-2016 DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 SUPERFAMILY SSF50692 1067 1213 1.02E-40 T 23-04-2016 IPR009010 Aspartate decarboxylase-like domain DC74_RS38915 3318596927fc9e20354fc4518ba20d90 1219 Gene3D G3DSA:2.20.25.90 56 102 9.3E-30 T 23-04-2016 DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 Pfam PF00455 DeoR C terminal sensor domain 95 252 2.0E-48 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 ProSitePatterns PS00894 DeoR-type HTH domain signature. 26 60 - T 23-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 Pfam PF08220 DeoR-like helix-turn-helix domain 26 78 1.3E-14 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 44 58 7.3E-6 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 58 76 7.3E-6 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 PANTHER PTHR30363 20 272 1.1E-63 T 23-04-2016 DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 SMART SM00420 26 78 5.9E-14 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 SMART SM01134 93 253 6.1E-61 T 23-04-2016 DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 Gene3D G3DSA:1.10.10.10 19 76 5.4E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 SUPERFAMILY SSF100950 95 253 7.01E-26 T 23-04-2016 DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 SUPERFAMILY SSF46785 24 84 1.01E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 PANTHER PTHR30363:SF1 20 272 1.1E-63 T 23-04-2016 DC74_RS22245 04cd7de5f4af4d7704f67b292f498197 279 Gene3D G3DSA:3.40.50.1360 95 236 5.9E-13 T 23-04-2016 DC74_RS16990 c9eee9a0630371410509b8559e4f87bf 176 Gene3D G3DSA:2.60.120.10 44 146 2.1E-16 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS16990 c9eee9a0630371410509b8559e4f87bf 176 Pfam PF05995 Cysteine dioxygenase type I 20 147 5.5E-20 T 23-04-2016 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|UniPathway: UPA00012 DC74_RS16990 c9eee9a0630371410509b8559e4f87bf 176 PANTHER PTHR12918 28 159 6.9E-28 T 23-04-2016 DC74_RS16990 c9eee9a0630371410509b8559e4f87bf 176 SUPERFAMILY SSF51182 20 148 2.06E-29 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 Gene3D G3DSA:3.40.50.720 148 234 1.7E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 Gene3D G3DSA:3.40.50.720 400 482 1.7E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 Gene3D G3DSA:1.10.1060.10 2 147 4.2E-38 T 23-04-2016 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 SUPERFAMILY SSF46548 6 155 1.52E-36 T 23-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 1.3E-24 T 23-04-2016 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 1.3E-24 T 23-04-2016 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 1.3E-24 T 23-04-2016 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 1.3E-24 T 23-04-2016 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 474 8.6E-211 T 23-04-2016 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 PANTHER PTHR11938 20 318 1.3E-145 T 23-04-2016 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 PANTHER PTHR11938 334 467 1.3E-145 T 23-04-2016 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 456 2.9E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 131 6.9E-22 T 23-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 SUPERFAMILY SSF51971 144 400 8.83E-66 T 23-04-2016 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 PANTHER PTHR11938:SF75 20 318 1.3E-145 T 23-04-2016 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 PANTHER PTHR11938:SF75 334 467 1.3E-145 T 23-04-2016 DC74_RS12265 1d31756879e65b71eef4cf1b2f213eeb 486 Gene3D G3DSA:3.50.50.60 235 399 2.9E-40 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS40290 a550f40aa42447adccb3709fde266966 117 Pfam PF00589 Phage integrase family 29 88 1.7E-8 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS40290 a550f40aa42447adccb3709fde266966 117 PANTHER PTHR30349 9 117 6.3E-15 T 23-04-2016 DC74_RS40290 a550f40aa42447adccb3709fde266966 117 SUPERFAMILY SSF56349 33 95 7.65E-16 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DC74_RS40290 a550f40aa42447adccb3709fde266966 117 PANTHER PTHR30349:SF20 9 117 6.3E-15 T 23-04-2016 DC74_RS40290 a550f40aa42447adccb3709fde266966 117 Gene3D G3DSA:1.10.443.10 16 93 2.3E-15 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS32705 fee9c295ca87f41f9753b24e3b7646bb 427 PANTHER PTHR23517:SF3 6 397 5.7E-43 T 23-04-2016 DC74_RS32705 fee9c295ca87f41f9753b24e3b7646bb 427 Gene3D G3DSA:1.20.1250.20 230 404 2.0E-17 T 23-04-2016 DC74_RS32705 fee9c295ca87f41f9753b24e3b7646bb 427 Gene3D G3DSA:1.20.1250.20 32 204 1.0E-24 T 23-04-2016 DC74_RS32705 fee9c295ca87f41f9753b24e3b7646bb 427 PANTHER PTHR23517 6 397 5.7E-43 T 23-04-2016 DC74_RS32705 fee9c295ca87f41f9753b24e3b7646bb 427 Pfam PF07690 Major Facilitator Superfamily 38 361 3.9E-32 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS32705 fee9c295ca87f41f9753b24e3b7646bb 427 SUPERFAMILY SSF103473 37 406 2.35E-48 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS27300 d86e0bad353d951478a7a8bcae0bb17f 226 SMART SM00448 6 119 7.4E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS27300 d86e0bad353d951478a7a8bcae0bb17f 226 Pfam PF00072 Response regulator receiver domain 8 119 1.8E-20 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS27300 d86e0bad353d951478a7a8bcae0bb17f 226 Gene3D G3DSA:1.10.10.10 165 209 1.8E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27300 d86e0bad353d951478a7a8bcae0bb17f 226 SUPERFAMILY SSF52172 6 164 1.1E-31 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS27300 d86e0bad353d951478a7a8bcae0bb17f 226 Gene3D G3DSA:3.40.50.2300 4 126 8.7E-27 T 23-04-2016 DC74_RS27300 d86e0bad353d951478a7a8bcae0bb17f 226 PIRSF PIRSF006171 4 226 4.7E-71 T 23-04-2016 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 DC74_RS27300 d86e0bad353d951478a7a8bcae0bb17f 226 PANTHER PTHR26402 6 197 1.5E-57 T 23-04-2016 DC74_RS27300 d86e0bad353d951478a7a8bcae0bb17f 226 PANTHER PTHR26402:SF434 6 197 1.5E-57 T 23-04-2016 DC74_RS04550 0e4744b501134c46e0375266235e117c 726 PANTHER PTHR33406 5 710 2.1E-90 T 23-04-2016 DC74_RS04550 0e4744b501134c46e0375266235e117c 726 Gene3D G3DSA:1.20.1640.10 127 327 5.8E-28 T 23-04-2016 DC74_RS04550 0e4744b501134c46e0375266235e117c 726 Gene3D G3DSA:1.20.1640.10 536 708 2.1E-28 T 23-04-2016 DC74_RS04550 0e4744b501134c46e0375266235e117c 726 Pfam PF03176 MMPL family 510 705 2.8E-27 T 23-04-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 DC74_RS04550 0e4744b501134c46e0375266235e117c 726 Pfam PF03176 MMPL family 73 363 4.3E-40 T 23-04-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 DC74_RS04550 0e4744b501134c46e0375266235e117c 726 SUPERFAMILY SSF82866 109 327 6.67E-29 T 23-04-2016 DC74_RS04550 0e4744b501134c46e0375266235e117c 726 SUPERFAMILY SSF82866 494 705 7.72E-26 T 23-04-2016 DC74_RS22380 2712a2796da94def093f665fc7b06c89 471 PANTHER PTHR11999 32 457 7.1E-184 T 23-04-2016 DC74_RS22380 2712a2796da94def093f665fc7b06c89 471 Gene3D G3DSA:3.40.640.10 85 333 4.9E-27 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS22380 2712a2796da94def093f665fc7b06c89 471 SUPERFAMILY SSF53383 30 454 6.13E-128 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS22380 2712a2796da94def093f665fc7b06c89 471 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 53 385 2.3E-71 T 23-04-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 DC74_RS22380 2712a2796da94def093f665fc7b06c89 471 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 36 452 1.6E-186 T 23-04-2016 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 DC74_RS22380 2712a2796da94def093f665fc7b06c89 471 PANTHER PTHR11999:SF111 32 457 7.1E-184 T 23-04-2016 DC74_RS37635 3db927e81e956f29bf6651e58753f06d 292 SUPERFAMILY SSF47616 126 249 7.8E-20 T 23-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like DC74_RS37635 3db927e81e956f29bf6651e58753f06d 292 PANTHER PTHR32419 13 256 1.2E-29 T 23-04-2016 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 DC74_RS37635 3db927e81e956f29bf6651e58753f06d 292 PANTHER PTHR32419:SF6 13 256 1.2E-29 T 23-04-2016 DC74_RS37635 3db927e81e956f29bf6651e58753f06d 292 Gene3D G3DSA:1.20.1050.10 128 248 4.1E-15 T 23-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like DC74_RS37635 3db927e81e956f29bf6651e58753f06d 292 Pfam PF13410 Glutathione S-transferase, C-terminal domain 167 238 5.1E-11 T 23-04-2016 DC74_RS35950 0f85b557bd7ea58d2ac7a6640618fbb7 244 SUPERFAMILY SSF46785 8 94 2.85E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35950 0f85b557bd7ea58d2ac7a6640618fbb7 244 SMART SM00418 17 96 1.6E-22 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS35950 0f85b557bd7ea58d2ac7a6640618fbb7 244 Gene3D G3DSA:1.10.10.10 4 95 7.0E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35950 0f85b557bd7ea58d2ac7a6640618fbb7 244 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 7.41E-8 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS35950 0f85b557bd7ea58d2ac7a6640618fbb7 244 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 7.41E-8 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS35950 0f85b557bd7ea58d2ac7a6640618fbb7 244 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 7.41E-8 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS35950 0f85b557bd7ea58d2ac7a6640618fbb7 244 PANTHER PTHR39168 12 241 7.6E-47 T 23-04-2016 DC74_RS35950 0f85b557bd7ea58d2ac7a6640618fbb7 244 PANTHER PTHR39168:SF1 12 241 7.6E-47 T 23-04-2016 DC74_RS35950 0f85b557bd7ea58d2ac7a6640618fbb7 244 Pfam PF12840 Helix-turn-helix domain 17 76 3.9E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS30730 4ad63b4ab7b0e4cca93c8d10738d1693 108 Pfam PF03091 CutA1 divalent ion tolerance protein 7 103 1.0E-32 T 23-04-2016 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 DC74_RS30730 4ad63b4ab7b0e4cca93c8d10738d1693 108 SUPERFAMILY SSF54913 2 104 7.41E-33 T 23-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta DC74_RS30730 4ad63b4ab7b0e4cca93c8d10738d1693 108 Gene3D G3DSA:3.30.70.830 2 104 1.5E-36 T 23-04-2016 DC74_RS30730 4ad63b4ab7b0e4cca93c8d10738d1693 108 PANTHER PTHR23419 5 103 7.9E-30 T 23-04-2016 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 DC74_RS37030 320c5fe321776606b81993062347058f 480 Gene3D G3DSA:1.20.1250.20 13 199 5.6E-26 T 23-04-2016 DC74_RS37030 320c5fe321776606b81993062347058f 480 Pfam PF07690 Major Facilitator Superfamily 19 406 5.4E-44 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS37030 320c5fe321776606b81993062347058f 480 PANTHER PTHR23501:SF65 11 465 1.8E-138 T 23-04-2016 DC74_RS37030 320c5fe321776606b81993062347058f 480 Gene3D G3DSA:1.20.1250.20 259 464 4.2E-13 T 23-04-2016 DC74_RS37030 320c5fe321776606b81993062347058f 480 PANTHER PTHR23501 11 465 1.8E-138 T 23-04-2016 DC74_RS37030 320c5fe321776606b81993062347058f 480 SUPERFAMILY SSF103473 6 199 7.46E-57 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS37030 320c5fe321776606b81993062347058f 480 SUPERFAMILY SSF103473 446 465 7.46E-57 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS37030 320c5fe321776606b81993062347058f 480 SUPERFAMILY SSF103473 250 417 7.46E-57 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS37030 320c5fe321776606b81993062347058f 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 78 100 1.2E-6 T 23-04-2016 DC74_RS37030 320c5fe321776606b81993062347058f 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 304 328 1.2E-6 T 23-04-2016 DC74_RS37030 320c5fe321776606b81993062347058f 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 397 416 1.2E-6 T 23-04-2016 DC74_RS37030 320c5fe321776606b81993062347058f 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 1.2E-6 T 23-04-2016 DC74_RS25045 406272a916c6940884db3da7ad787bf5 400 Pfam PF13560 Helix-turn-helix domain 10 64 2.2E-7 T 23-04-2016 DC74_RS25045 406272a916c6940884db3da7ad787bf5 400 Gene3D G3DSA:1.10.260.40 8 70 2.0E-10 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS25045 406272a916c6940884db3da7ad787bf5 400 Gene3D G3DSA:1.25.40.10 146 290 9.1E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS25045 406272a916c6940884db3da7ad787bf5 400 SMART SM00530 12 66 3.5E-6 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS25045 406272a916c6940884db3da7ad787bf5 400 SUPERFAMILY SSF47413 8 69 5.35E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 PANTHER PTHR11689 1 472 2.6E-118 T 23-04-2016 DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 Gene3D G3DSA:1.10.3080.10 2 424 1.7E-96 T 23-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 Pfam PF00654 Voltage gated chloride channel 60 403 3.8E-97 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 Pfam PF00571 CBS domain 444 490 5.4E-4 T 23-04-2016 IPR000644 CBS domain DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 PANTHER PTHR11689:SF14 1 472 2.6E-118 T 23-04-2016 DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 PRINTS PR00762 Chloride channel signature 154 173 5.0E-27 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 PRINTS PR00762 Chloride channel signature 74 91 5.0E-27 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 PRINTS PR00762 Chloride channel signature 371 390 5.0E-27 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 PRINTS PR00762 Chloride channel signature 318 338 5.0E-27 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 PRINTS PR00762 Chloride channel signature 353 369 5.0E-27 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 SUPERFAMILY SSF81340 2 422 4.19E-110 T 23-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 Gene3D G3DSA:3.10.580.10 435 556 6.5E-15 T 23-04-2016 DC74_RS35455 c85c48360aa904052adfd02cf6f89fcc 567 SUPERFAMILY SSF54631 434 556 1.94E-13 T 23-04-2016 DC74_RS23445 a90847acbacb8a1875bc13fc8cd78dfa 255 PANTHER PTHR10804 1 253 6.2E-94 T 23-04-2016 DC74_RS23445 a90847acbacb8a1875bc13fc8cd78dfa 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 3.1E-20 T 23-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase DC74_RS23445 a90847acbacb8a1875bc13fc8cd78dfa 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 3.1E-20 T 23-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase DC74_RS23445 a90847acbacb8a1875bc13fc8cd78dfa 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 3.1E-20 T 23-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase DC74_RS23445 a90847acbacb8a1875bc13fc8cd78dfa 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 3.1E-20 T 23-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase DC74_RS23445 a90847acbacb8a1875bc13fc8cd78dfa 255 Gene3D G3DSA:3.90.230.10 4 254 8.4E-77 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS23445 a90847acbacb8a1875bc13fc8cd78dfa 255 SUPERFAMILY SSF55920 4 253 3.27E-74 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS23445 a90847acbacb8a1875bc13fc8cd78dfa 255 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 253 1.7E-74 T 23-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 DC74_RS23445 a90847acbacb8a1875bc13fc8cd78dfa 255 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 36.063 T 23-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 DC74_RS23445 a90847acbacb8a1875bc13fc8cd78dfa 255 PANTHER PTHR10804:SF41 1 253 6.2E-94 T 23-04-2016 DC74_RS23445 a90847acbacb8a1875bc13fc8cd78dfa 255 Pfam PF00557 Metallopeptidase family M24 12 246 2.4E-44 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 Gene3D G3DSA:3.30.565.10 326 473 4.4E-38 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 SMART SM00387 364 475 4.7E-26 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 Gene3D G3DSA:2.60.120.10 15 126 3.6E-13 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 PANTHER PTHR24423:SF555 286 487 1.3E-127 T 23-04-2016 DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 PANTHER PTHR24423:SF555 112 185 1.3E-127 T 23-04-2016 DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 PANTHER PTHR24423:SF555 3 44 1.3E-127 T 23-04-2016 DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 PANTHER PTHR24423 286 487 1.3E-127 T 23-04-2016 DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 PANTHER PTHR24423 112 185 1.3E-127 T 23-04-2016 DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 PANTHER PTHR24423 3 44 1.3E-127 T 23-04-2016 DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 Pfam PF00027 Cyclic nucleotide-binding domain 44 125 1.6E-6 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 SUPERFAMILY SSF55874 309 477 2.23E-38 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 474 2.8E-20 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 3.7E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 3.7E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 3.7E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 472 3.7E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS04730 03106c2d2927c0ef6abd2dd604c2d8f9 493 SUPERFAMILY SSF51206 13 130 9.17E-15 T 23-04-2016 IPR018490 Cyclic nucleotide-binding-like DC74_RS03075 a1df251c4bf82421b0509d8f4f45adeb 412 PANTHER PTHR23514 15 400 1.7E-97 T 23-04-2016 DC74_RS03075 a1df251c4bf82421b0509d8f4f45adeb 412 SUPERFAMILY SSF103473 13 399 2.35E-46 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS03075 a1df251c4bf82421b0509d8f4f45adeb 412 Pfam PF07690 Major Facilitator Superfamily 30 363 3.4E-24 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS03075 a1df251c4bf82421b0509d8f4f45adeb 412 PANTHER PTHR23514:SF13 15 400 1.7E-97 T 23-04-2016 DC74_RS03075 a1df251c4bf82421b0509d8f4f45adeb 412 Gene3D G3DSA:1.20.1250.20 25 192 7.4E-19 T 23-04-2016 DC74_RS03075 a1df251c4bf82421b0509d8f4f45adeb 412 Gene3D G3DSA:1.20.1250.20 222 396 7.8E-15 T 23-04-2016 DC74_RS01560 0fc2b945d4801b7dcd737202bfb4bc9a 231 Pfam PF13298 DNA polymerase Ligase (LigD) 44 154 5.6E-37 T 23-04-2016 IPR014144 DNA ligase D, 3'-phosphoesterase domain DC74_RS01560 0fc2b945d4801b7dcd737202bfb4bc9a 231 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 13 176 1.5E-60 T 23-04-2016 IPR014144 DNA ligase D, 3'-phosphoesterase domain DC74_RS01560 0fc2b945d4801b7dcd737202bfb4bc9a 231 PANTHER PTHR39465 4 209 3.5E-47 T 23-04-2016 DC74_RS31535 17b615149571283141c6336f2541d46d 259 PANTHER PTHR22748 1 259 2.5E-114 T 23-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 DC74_RS31535 17b615149571283141c6336f2541d46d 259 Gene3D G3DSA:3.60.10.10 1 258 4.8E-77 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS31535 17b615149571283141c6336f2541d46d 259 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 256 7.9E-61 T 23-04-2016 DC74_RS31535 17b615149571283141c6336f2541d46d 259 PANTHER PTHR22748:SF7 1 259 2.5E-114 T 23-04-2016 DC74_RS31535 17b615149571283141c6336f2541d46d 259 SUPERFAMILY SSF56219 1 258 3.53E-69 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS31535 17b615149571283141c6336f2541d46d 259 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 258 5.7E-81 T 23-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 DC74_RS31535 17b615149571283141c6336f2541d46d 259 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 5.7E-21 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS14780 4bd7b5832ee60a8268172fd114d9332c 474 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 26 450 1.4E-40 T 23-04-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 DC74_RS14780 4bd7b5832ee60a8268172fd114d9332c 474 PANTHER PTHR31806 14 473 4.5E-63 T 23-04-2016 DC74_RS14780 4bd7b5832ee60a8268172fd114d9332c 474 PIRSF PIRSF002744 1 474 2.5E-92 T 23-04-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 DC74_RS15515 e32a3b7e95482355c14534e4f4684249 330 PANTHER PTHR12862:SF4 8 312 3.6E-98 T 23-04-2016 DC74_RS15515 e32a3b7e95482355c14534e4f4684249 330 SUPERFAMILY SSF53067 7 115 4.26E-12 T 23-04-2016 DC74_RS15515 e32a3b7e95482355c14534e4f4684249 330 PANTHER PTHR12862 8 312 3.6E-98 T 23-04-2016 DC74_RS15515 e32a3b7e95482355c14534e4f4684249 330 SUPERFAMILY SSF53067 124 312 3.51E-34 T 23-04-2016 DC74_RS15515 e32a3b7e95482355c14534e4f4684249 330 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 10 307 1.8E-12 T 23-04-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type DC74_RS15515 e32a3b7e95482355c14534e4f4684249 330 Gene3D G3DSA:3.30.420.40 129 296 9.0E-8 T 23-04-2016 DC74_RS05425 05ef7b5e4c6a8fe2c581026bdc008ff9 801 Gene3D G3DSA:2.130.10.10 165 342 3.9E-5 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS05425 05ef7b5e4c6a8fe2c581026bdc008ff9 801 Gene3D G3DSA:2.130.10.10 9 71 3.9E-5 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS05425 05ef7b5e4c6a8fe2c581026bdc008ff9 801 Gene3D G3DSA:2.60.40.10 586 653 5.9E-14 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS05425 05ef7b5e4c6a8fe2c581026bdc008ff9 801 PANTHER PTHR23303 446 633 7.3E-19 T 23-04-2016 DC74_RS05425 05ef7b5e4c6a8fe2c581026bdc008ff9 801 PANTHER PTHR23303 172 430 7.3E-19 T 23-04-2016 DC74_RS05425 05ef7b5e4c6a8fe2c581026bdc008ff9 801 SUPERFAMILY SSF50969 252 529 2.28E-6 T 23-04-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like DC74_RS05425 05ef7b5e4c6a8fe2c581026bdc008ff9 801 SUPERFAMILY SSF117074 569 663 3.01E-16 T 23-04-2016 DC74_RS09620 50c2be734a47c42c2b3e58d3ebc88e8b 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 4.0E-36 T 23-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 DC74_RS09620 50c2be734a47c42c2b3e58d3ebc88e8b 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 4.0E-36 T 23-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 DC74_RS09620 50c2be734a47c42c2b3e58d3ebc88e8b 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 4.0E-36 T 23-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 DC74_RS09620 50c2be734a47c42c2b3e58d3ebc88e8b 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 4.0E-36 T 23-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 DC74_RS09620 50c2be734a47c42c2b3e58d3ebc88e8b 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 4.0E-36 T 23-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 DC74_RS09620 50c2be734a47c42c2b3e58d3ebc88e8b 183 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 4.8E-54 T 23-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 DC74_RS09620 50c2be734a47c42c2b3e58d3ebc88e8b 183 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 155 1.7E-35 T 23-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 DC74_RS09620 50c2be734a47c42c2b3e58d3ebc88e8b 183 SUPERFAMILY SSF53098 1 156 8.34E-46 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS09620 50c2be734a47c42c2b3e58d3ebc88e8b 183 Gene3D G3DSA:3.30.420.10 1 156 7.0E-56 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS09620 50c2be734a47c42c2b3e58d3ebc88e8b 183 PANTHER PTHR30194 1 171 1.1E-64 T 23-04-2016 DC74_RS09620 50c2be734a47c42c2b3e58d3ebc88e8b 183 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 23-04-2016 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 DC74_RS09620 50c2be734a47c42c2b3e58d3ebc88e8b 183 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 46.047 T 23-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 DC74_RS37485 d7a67a33414126d0be5961a7e7d47c41 225 Pfam PF11139 Sap, sulfolipid-1-addressing protein 8 220 6.3E-55 T 23-04-2016 IPR021315 Glycolipid exporter Gap/Sap DC74_RS37485 d7a67a33414126d0be5961a7e7d47c41 225 PANTHER PTHR42276:SF2 2 223 2.5E-34 T 23-04-2016 DC74_RS37485 d7a67a33414126d0be5961a7e7d47c41 225 PANTHER PTHR42276 2 223 2.5E-34 T 23-04-2016 DC74_RS05090 90b81f40a931388953d80631d7b280d5 522 PANTHER PTHR23501 9 499 4.4E-111 T 23-04-2016 DC74_RS05090 90b81f40a931388953d80631d7b280d5 522 SUPERFAMILY SSF103473 3 201 1.44E-54 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05090 90b81f40a931388953d80631d7b280d5 522 SUPERFAMILY SSF103473 253 424 1.44E-54 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05090 90b81f40a931388953d80631d7b280d5 522 SUPERFAMILY SSF103473 476 498 1.44E-54 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05090 90b81f40a931388953d80631d7b280d5 522 Gene3D G3DSA:1.20.1250.20 11 200 3.8E-24 T 23-04-2016 DC74_RS05090 90b81f40a931388953d80631d7b280d5 522 Pfam PF07690 Major Facilitator Superfamily 19 414 4.2E-42 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS05090 90b81f40a931388953d80631d7b280d5 522 PANTHER PTHR23501:SF65 9 499 4.4E-111 T 23-04-2016 DC74_RS05090 90b81f40a931388953d80631d7b280d5 522 Gene3D G3DSA:1.20.1250.20 475 503 9.7E-16 T 23-04-2016 DC74_RS05090 90b81f40a931388953d80631d7b280d5 522 Gene3D G3DSA:1.20.1250.20 270 425 9.7E-16 T 23-04-2016 DC74_RS16205 9f5712537bb0ebe03078a856b164c499 256 Pfam PF00392 Bacterial regulatory proteins, gntR family 38 84 4.1E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS16205 9f5712537bb0ebe03078a856b164c499 256 SUPERFAMILY SSF64288 77 250 1.88E-41 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS16205 9f5712537bb0ebe03078a856b164c499 256 SMART SM00345 29 85 9.7E-5 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS16205 9f5712537bb0ebe03078a856b164c499 256 SMART SM00866 105 245 8.1E-34 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS16205 9f5712537bb0ebe03078a856b164c499 256 Gene3D G3DSA:3.40.1410.10 85 250 1.1E-42 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS16205 9f5712537bb0ebe03078a856b164c499 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 3.6E-9 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS16205 9f5712537bb0ebe03078a856b164c499 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 3.6E-9 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS16205 9f5712537bb0ebe03078a856b164c499 256 SUPERFAMILY SSF46785 25 94 3.16E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16205 9f5712537bb0ebe03078a856b164c499 256 Pfam PF07702 UTRA domain 106 244 1.4E-32 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS16205 9f5712537bb0ebe03078a856b164c499 256 PANTHER PTHR11751 39 92 8.0E-13 T 23-04-2016 DC74_RS16205 9f5712537bb0ebe03078a856b164c499 256 PANTHER PTHR11751 138 157 8.0E-13 T 23-04-2016 DC74_RS16205 9f5712537bb0ebe03078a856b164c499 256 Gene3D G3DSA:1.10.10.10 21 84 3.2E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20865 3891860bcdafc614379711eded44d7c2 308 Pfam PF05368 NmrA-like family 4 246 4.8E-26 T 23-04-2016 IPR008030 NmrA-like domain DC74_RS20865 3891860bcdafc614379711eded44d7c2 308 SUPERFAMILY SSF51735 3 288 2.04E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20865 3891860bcdafc614379711eded44d7c2 308 PANTHER PTHR14194 4 301 1.7E-41 T 23-04-2016 DC74_RS20865 3891860bcdafc614379711eded44d7c2 308 PANTHER PTHR14194:SF46 4 301 1.7E-41 T 23-04-2016 DC74_RS20865 3891860bcdafc614379711eded44d7c2 308 Gene3D G3DSA:3.40.50.720 3 241 1.6E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03450 bad69a5330e21716fff232aa7dd4fae4 332 Gene3D G3DSA:3.40.50.150 89 329 2.1E-48 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS03450 bad69a5330e21716fff232aa7dd4fae4 332 SUPERFAMILY SSF46785 7 86 1.63E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03450 bad69a5330e21716fff232aa7dd4fae4 332 Pfam PF16864 Dimerisation domain 6 75 9.9E-7 T 23-04-2016 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain DC74_RS03450 bad69a5330e21716fff232aa7dd4fae4 332 Pfam PF00891 O-methyltransferase 127 317 9.0E-40 T 23-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 DC74_RS03450 bad69a5330e21716fff232aa7dd4fae4 332 SUPERFAMILY SSF53335 91 321 1.02E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS03450 bad69a5330e21716fff232aa7dd4fae4 332 PANTHER PTHR11746 6 314 2.8E-49 T 23-04-2016 DC74_RS03450 bad69a5330e21716fff232aa7dd4fae4 332 Gene3D G3DSA:1.10.10.10 3 78 1.0E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03450 bad69a5330e21716fff232aa7dd4fae4 332 PIRSF PIRSF005739 4 331 1.7E-30 T 23-04-2016 IPR016461 O-methyltransferase COMT-type GO:0008168 DC74_RS10275 d7ceb87c443174f8ae7cba998b110fc2 316 Pfam PF13280 WYL domain 144 311 3.0E-29 T 23-04-2016 IPR026881 WYL domain DC74_RS10275 d7ceb87c443174f8ae7cba998b110fc2 316 PANTHER PTHR34580 1 314 6.2E-164 T 23-04-2016 DC74_RS10275 d7ceb87c443174f8ae7cba998b110fc2 316 PANTHER PTHR34580:SF2 1 314 6.2E-164 T 23-04-2016 DC74_RS10275 d7ceb87c443174f8ae7cba998b110fc2 316 PIRSF PIRSF016838 2 316 2.0E-87 T 23-04-2016 IPR028349 Protein PafC DC74_RS01735 214b0e1f3a8aa3c13107db4f7888ca5a 343 SUPERFAMILY SSF50129 2 166 1.83E-44 T 23-04-2016 IPR011032 GroES-like DC74_RS01735 214b0e1f3a8aa3c13107db4f7888ca5a 343 PANTHER PTHR11695 12 343 1.1E-115 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS01735 214b0e1f3a8aa3c13107db4f7888ca5a 343 PANTHER PTHR11695:SF601 12 343 1.1E-115 T 23-04-2016 DC74_RS01735 214b0e1f3a8aa3c13107db4f7888ca5a 343 Pfam PF00107 Zinc-binding dehydrogenase 177 305 1.5E-23 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS01735 214b0e1f3a8aa3c13107db4f7888ca5a 343 SUPERFAMILY SSF51735 146 310 5.48E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01735 214b0e1f3a8aa3c13107db4f7888ca5a 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS01735 214b0e1f3a8aa3c13107db4f7888ca5a 343 Gene3D G3DSA:3.40.50.720 169 288 2.6E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01735 214b0e1f3a8aa3c13107db4f7888ca5a 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 126 9.1E-27 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS01735 214b0e1f3a8aa3c13107db4f7888ca5a 343 Gene3D G3DSA:3.90.180.10 2 168 3.9E-40 T 23-04-2016 IPR011032 GroES-like DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 2.7E-26 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 2.7E-26 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 2.7E-26 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 2.7E-26 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 Gene3D G3DSA:1.10.275.10 9 114 2.0E-34 T 23-04-2016 IPR024083 Fumarase/histidase, N-terminal DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 8.3E-55 T 23-04-2016 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 8.3E-55 T 23-04-2016 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 8.3E-55 T 23-04-2016 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 PRINTS PR00145 Argininosuccinate lyase family signature 319 338 8.3E-55 T 23-04-2016 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 8.3E-55 T 23-04-2016 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 8.3E-55 T 23-04-2016 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 464 1.3E-181 T 23-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 PANTHER PTHR11444:SF3 9 464 4.7E-213 T 23-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 ProSitePatterns PS00163 Fumarate lyases signature. 284 293 - T 23-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 Pfam PF14698 Argininosuccinate lyase C-terminal 372 437 7.0E-22 T 23-04-2016 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 Gene3D G3DSA:1.10.40.30 383 439 1.1E-28 T 23-04-2016 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 SUPERFAMILY SSF48557 13 463 9.9E-137 T 23-04-2016 IPR008948 L-Aspartase-like GO:0003824 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 462 40.742 T 23-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 Gene3D G3DSA:1.20.200.10 115 382 7.7E-99 T 23-04-2016 DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 Pfam PF00206 Lyase 21 309 7.7E-63 T 23-04-2016 IPR022761 Fumarate lyase, N-terminal DC74_RS09875 c96b8ade87d9f1430593cc88b22ce4b2 475 PANTHER PTHR11444 9 464 4.7E-213 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS14755 4859a56e775163055483c7f721f173ed 278 PANTHER PTHR32243 1 278 3.3E-89 T 23-04-2016 DC74_RS14755 4859a56e775163055483c7f721f173ed 278 SUPERFAMILY SSF161098 7 275 5.1E-61 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS14755 4859a56e775163055483c7f721f173ed 278 Gene3D G3DSA:1.10.3720.10 7 265 1.6E-58 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS14755 4859a56e775163055483c7f721f173ed 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 271 1.6E-17 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS14755 4859a56e775163055483c7f721f173ed 278 PANTHER PTHR32243:SF31 1 278 3.3E-89 T 23-04-2016 IPR030165 sn-glycerol-3-phosphate transport system permease protein UgpE GO:0001407|GO:0005887|GO:0015794|GO:0055052 DC74_RS30190 606ec0667a625c1a198b444cc869f6b0 304 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 117 234 7.3E-13 T 23-04-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain DC74_RS30190 606ec0667a625c1a198b444cc869f6b0 304 SUPERFAMILY SSF55961 109 240 1.37E-18 T 23-04-2016 DC74_RS30190 606ec0667a625c1a198b444cc869f6b0 304 Gene3D G3DSA:3.30.530.20 111 219 2.1E-7 T 23-04-2016 IPR023393 START-like domain DC74_RS30190 606ec0667a625c1a198b444cc869f6b0 304 PANTHER PTHR33824:SF2 13 275 1.1E-101 T 23-04-2016 DC74_RS30190 606ec0667a625c1a198b444cc869f6b0 304 PANTHER PTHR33824 13 275 1.1E-101 T 23-04-2016 DC74_RS10600 c043dc60405543cd5b93d71d00a44ec0 349 Gene3D G3DSA:3.90.1200.10 135 323 3.0E-35 T 23-04-2016 DC74_RS10600 c043dc60405543cd5b93d71d00a44ec0 349 PANTHER PTHR21310 18 258 9.5E-21 T 23-04-2016 DC74_RS10600 c043dc60405543cd5b93d71d00a44ec0 349 SUPERFAMILY SSF56112 16 322 6.12E-61 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS10600 c043dc60405543cd5b93d71d00a44ec0 349 Pfam PF01636 Phosphotransferase enzyme family 43 299 4.3E-49 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS10600 c043dc60405543cd5b93d71d00a44ec0 349 PANTHER PTHR21310:SF14 18 258 9.5E-21 T 23-04-2016 DC74_RS05470 5c8b6195316013787c5f23a8f38f6d12 512 SUPERFAMILY SSF51126 59 310 7.86E-25 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS05470 5c8b6195316013787c5f23a8f38f6d12 512 SUPERFAMILY SSF51126 344 367 7.86E-25 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS05470 5c8b6195316013787c5f23a8f38f6d12 512 SMART SM00710 296 333 180.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS05470 5c8b6195316013787c5f23a8f38f6d12 512 SMART SM00710 273 295 630.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS05470 5c8b6195316013787c5f23a8f38f6d12 512 SMART SM00710 213 248 620.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS05470 5c8b6195316013787c5f23a8f38f6d12 512 SMART SM00710 344 365 410.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS05470 5c8b6195316013787c5f23a8f38f6d12 512 SMART SM00710 249 271 11.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS05470 5c8b6195316013787c5f23a8f38f6d12 512 SMART SM00710 165 187 88.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS05470 5c8b6195316013787c5f23a8f38f6d12 512 Gene3D G3DSA:2.160.20.10 57 380 4.4E-22 T 23-04-2016 IPR012334 Pectin lyase fold DC74_RS05470 5c8b6195316013787c5f23a8f38f6d12 512 Pfam PF13229 Right handed beta helix region 164 314 3.8E-14 T 23-04-2016 DC74_RS05470 5c8b6195316013787c5f23a8f38f6d12 512 SMART SM00722 164 318 1.4E-5 T 23-04-2016 IPR006633 Carbohydrate-binding/sugar hydrolysis domain DC74_RS05525 da5543777792851fd6cae13d29aaeae0 183 PANTHER PTHR21047 7 174 2.1E-57 T 23-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 DC74_RS05525 da5543777792851fd6cae13d29aaeae0 183 Gene3D G3DSA:2.60.120.10 8 179 8.4E-61 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS05525 da5543777792851fd6cae13d29aaeae0 183 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 182 3.0E-88 T 23-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 DC74_RS05525 da5543777792851fd6cae13d29aaeae0 183 SUPERFAMILY SSF51182 8 178 1.2E-57 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS05525 da5543777792851fd6cae13d29aaeae0 183 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 174 1.7E-54 T 23-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 DC74_RS22235 28ab2dedd8b3ceaa0b5567761f3f25e1 275 Pfam PF00797 N-acetyltransferase 29 263 7.0E-67 T 23-04-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 DC74_RS22235 28ab2dedd8b3ceaa0b5567761f3f25e1 275 PANTHER PTHR11786 12 262 2.1E-54 T 23-04-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 DC74_RS22235 28ab2dedd8b3ceaa0b5567761f3f25e1 275 PRINTS PR01543 Arylamine N-acetyltransferase signature 136 156 1.8E-8 T 23-04-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 DC74_RS22235 28ab2dedd8b3ceaa0b5567761f3f25e1 275 PRINTS PR01543 Arylamine N-acetyltransferase signature 77 99 1.8E-8 T 23-04-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 DC74_RS22235 28ab2dedd8b3ceaa0b5567761f3f25e1 275 PRINTS PR01543 Arylamine N-acetyltransferase signature 53 76 1.8E-8 T 23-04-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 DC74_RS22235 28ab2dedd8b3ceaa0b5567761f3f25e1 275 PRINTS PR01543 Arylamine N-acetyltransferase signature 29 52 1.8E-8 T 23-04-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 DC74_RS22235 28ab2dedd8b3ceaa0b5567761f3f25e1 275 PANTHER PTHR11786:SF0 12 262 2.1E-54 T 23-04-2016 DC74_RS22235 28ab2dedd8b3ceaa0b5567761f3f25e1 275 SUPERFAMILY SSF54001 10 269 6.67E-73 T 23-04-2016 DC74_RS22235 28ab2dedd8b3ceaa0b5567761f3f25e1 275 Gene3D G3DSA:3.30.2140.10 191 268 1.3E-51 T 23-04-2016 DC74_RS22235 28ab2dedd8b3ceaa0b5567761f3f25e1 275 Gene3D G3DSA:3.30.2140.10 10 93 1.3E-51 T 23-04-2016 DC74_RS07945 919bcd66de3286defe8c9d848b9b7ac4 683 Pfam PF00326 Prolyl oligopeptidase family 477 673 3.1E-43 T 23-04-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 DC74_RS07945 919bcd66de3286defe8c9d848b9b7ac4 683 PANTHER PTHR11731:SF110 2 21 1.4E-97 T 23-04-2016 DC74_RS07945 919bcd66de3286defe8c9d848b9b7ac4 683 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 108 355 1.8E-31 T 23-04-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 DC74_RS07945 919bcd66de3286defe8c9d848b9b7ac4 683 Pfam PF07676 WD40-like Beta Propeller Repeat 5 24 0.038 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS07945 919bcd66de3286defe8c9d848b9b7ac4 683 PANTHER PTHR11731 60 682 1.4E-97 T 23-04-2016 DC74_RS07945 919bcd66de3286defe8c9d848b9b7ac4 683 PANTHER PTHR11731 2 21 1.4E-97 T 23-04-2016 DC74_RS07945 919bcd66de3286defe8c9d848b9b7ac4 683 PANTHER PTHR11731:SF110 60 682 1.4E-97 T 23-04-2016 DC74_RS07945 919bcd66de3286defe8c9d848b9b7ac4 683 Gene3D G3DSA:3.40.50.1820 431 673 5.5E-68 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS07945 919bcd66de3286defe8c9d848b9b7ac4 683 Gene3D G3DSA:2.140.10.30 2 358 2.3E-59 T 23-04-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 DC74_RS07945 919bcd66de3286defe8c9d848b9b7ac4 683 SUPERFAMILY SSF53474 431 673 2.81E-53 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS07945 919bcd66de3286defe8c9d848b9b7ac4 683 SUPERFAMILY SSF82171 3 357 4.58E-25 T 23-04-2016 DC74_RS34455 3028323a81d885bbe7efd2dfa47a2c02 243 PRINTS PR01837 MgtC/SapB protein signature 88 112 2.2E-41 T 23-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 DC74_RS34455 3028323a81d885bbe7efd2dfa47a2c02 243 PRINTS PR01837 MgtC/SapB protein signature 35 53 2.2E-41 T 23-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 DC74_RS34455 3028323a81d885bbe7efd2dfa47a2c02 243 PRINTS PR01837 MgtC/SapB protein signature 61 83 2.2E-41 T 23-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 DC74_RS34455 3028323a81d885bbe7efd2dfa47a2c02 243 PRINTS PR01837 MgtC/SapB protein signature 16 35 2.2E-41 T 23-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 DC74_RS34455 3028323a81d885bbe7efd2dfa47a2c02 243 Pfam PF02308 MgtC family 13 132 1.4E-33 T 23-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 DC74_RS34455 3028323a81d885bbe7efd2dfa47a2c02 243 PANTHER PTHR33778 1 236 5.6E-84 T 23-04-2016 DC74_RS34455 3028323a81d885bbe7efd2dfa47a2c02 243 PANTHER PTHR33778:SF3 1 236 5.6E-84 T 23-04-2016 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 SUPERFAMILY SSF51905 285 380 7.25E-57 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 SUPERFAMILY SSF51905 5 197 7.25E-57 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 PANTHER PTHR13789 3 446 2.6E-79 T 23-04-2016 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 PANTHER PTHR13789:SF90 3 446 2.6E-79 T 23-04-2016 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 Pfam PF01494 FAD binding domain 5 363 7.5E-68 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 Gene3D G3DSA:3.50.50.60 124 202 3.3E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 Gene3D G3DSA:3.50.50.60 5 70 3.3E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 Gene3D G3DSA:3.50.50.60 286 370 3.3E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 349 8.3E-41 T 23-04-2016 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 8.3E-41 T 23-04-2016 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 329 8.3E-41 T 23-04-2016 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 176 191 8.3E-41 T 23-04-2016 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 349 365 8.3E-41 T 23-04-2016 DC74_RS11905 50d591ae36294e78f6344a78a606ea4f 517 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 8.3E-41 T 23-04-2016 DC74_RS09505 03b1e555d296046c4ec903af4457a3c7 394 SUPERFAMILY SSF103263 3 390 1.07E-136 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09505 03b1e555d296046c4ec903af4457a3c7 394 Gene3D G3DSA:3.60.150.10 4 391 1.6E-152 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09505 03b1e555d296046c4ec903af4457a3c7 394 TIGRFAM TIGR00033 aroC: chorismate synthase 4 374 1.4E-138 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09505 03b1e555d296046c4ec903af4457a3c7 394 PANTHER PTHR21085 2 91 5.6E-169 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09505 03b1e555d296046c4ec903af4457a3c7 394 PANTHER PTHR21085 109 393 5.6E-169 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09505 03b1e555d296046c4ec903af4457a3c7 394 ProSitePatterns PS00788 Chorismate synthase signature 2. 136 152 - T 23-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09505 03b1e555d296046c4ec903af4457a3c7 394 ProSitePatterns PS00787 Chorismate synthase signature 1. 10 25 - T 23-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09505 03b1e555d296046c4ec903af4457a3c7 394 Pfam PF01264 Chorismate synthase 4 368 6.0E-116 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09505 03b1e555d296046c4ec903af4457a3c7 394 Hamap MF_00300 Chorismate synthase [aroC]. 4 376 33.983 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09505 03b1e555d296046c4ec903af4457a3c7 394 ProSitePatterns PS00789 Chorismate synthase signature 3. 343 359 - T 23-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS09505 03b1e555d296046c4ec903af4457a3c7 394 PIRSF PIRSF001456 1 386 3.4E-125 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS35695 85ef9efed27c2a90a1b806edb79872ee 195 Gene3D G3DSA:1.10.357.10 1 183 1.4E-42 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS35695 85ef9efed27c2a90a1b806edb79872ee 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 13 42 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS35695 85ef9efed27c2a90a1b806edb79872ee 195 PANTHER PTHR30055 1 180 9.8E-49 T 23-04-2016 DC74_RS35695 85ef9efed27c2a90a1b806edb79872ee 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 13 1.6E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS35695 85ef9efed27c2a90a1b806edb79872ee 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 44 1.6E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS35695 85ef9efed27c2a90a1b806edb79872ee 195 PANTHER PTHR30055:SF71 1 180 9.8E-49 T 23-04-2016 DC74_RS35695 85ef9efed27c2a90a1b806edb79872ee 195 SUPERFAMILY SSF46689 1 64 8.72E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS35695 85ef9efed27c2a90a1b806edb79872ee 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 46 2.0E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS35695 85ef9efed27c2a90a1b806edb79872ee 195 SUPERFAMILY SSF48498 69 183 1.63E-16 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS25850 18b421a3bfb978a2c75216ead13b3528 599 Gene3D G3DSA:3.90.76.10 83 255 1.3E-27 T 23-04-2016 DC74_RS25850 18b421a3bfb978a2c75216ead13b3528 599 Gene3D G3DSA:3.10.105.10 366 567 1.8E-35 T 23-04-2016 DC74_RS25850 18b421a3bfb978a2c75216ead13b3528 599 PIRSF PIRSF002741 19 599 2.9E-54 T 23-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DC74_RS25850 18b421a3bfb978a2c75216ead13b3528 599 SUPERFAMILY SSF53850 70 587 8.87E-84 T 23-04-2016 DC74_RS25850 18b421a3bfb978a2c75216ead13b3528 599 PANTHER PTHR30290:SF31 1 48 2.3E-129 T 23-04-2016 DC74_RS25850 18b421a3bfb978a2c75216ead13b3528 599 PANTHER PTHR30290:SF31 71 590 2.3E-129 T 23-04-2016 DC74_RS25850 18b421a3bfb978a2c75216ead13b3528 599 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 118 513 1.3E-66 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain DC74_RS25850 18b421a3bfb978a2c75216ead13b3528 599 PANTHER PTHR30290 1 48 2.3E-129 T 23-04-2016 DC74_RS25850 18b421a3bfb978a2c75216ead13b3528 599 PANTHER PTHR30290 71 590 2.3E-129 T 23-04-2016 DC74_RS25850 18b421a3bfb978a2c75216ead13b3528 599 Gene3D G3DSA:3.40.190.10 256 365 3.3E-14 T 23-04-2016 DC74_RS31300 6b0017e78938b02663a4bf10b601e1b9 172 Gene3D G3DSA:3.40.630.30 1 137 6.7E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31300 6b0017e78938b02663a4bf10b601e1b9 172 Pfam PF00583 Acetyltransferase (GNAT) family 65 133 5.4E-10 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS31300 6b0017e78938b02663a4bf10b601e1b9 172 SUPERFAMILY SSF55729 1 135 6.49E-19 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS09855 b13bccc1423a788a8b9a1275d28ad818 223 PANTHER PTHR10434:SF21 3 220 4.6E-73 T 23-04-2016 DC74_RS09855 b13bccc1423a788a8b9a1275d28ad818 223 Gene3D G3DSA:3.40.1130.10 12 206 1.1E-32 T 23-04-2016 DC74_RS09855 b13bccc1423a788a8b9a1275d28ad818 223 Pfam PF01553 Acyltransferase 20 150 9.9E-25 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS09855 b13bccc1423a788a8b9a1275d28ad818 223 PANTHER PTHR10434 3 220 4.6E-73 T 23-04-2016 DC74_RS09855 b13bccc1423a788a8b9a1275d28ad818 223 SMART SM00563 34 153 2.2E-34 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS09855 b13bccc1423a788a8b9a1275d28ad818 223 SUPERFAMILY SSF69593 10 219 1.2E-50 T 23-04-2016 DC74_RS00115 44a356ad88e3eeb032a8c59341c8a69b 69 PRINTS PR00050 Cold shock protein signature 25 34 5.6E-17 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS00115 44a356ad88e3eeb032a8c59341c8a69b 69 PRINTS PR00050 Cold shock protein signature 40 58 5.6E-17 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS00115 44a356ad88e3eeb032a8c59341c8a69b 69 PRINTS PR00050 Cold shock protein signature 4 19 5.6E-17 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS00115 44a356ad88e3eeb032a8c59341c8a69b 69 PANTHER PTHR11544 1 68 2.8E-38 T 23-04-2016 DC74_RS00115 44a356ad88e3eeb032a8c59341c8a69b 69 PIRSF PIRSF002599 1 69 1.1E-24 T 23-04-2016 IPR012156 Cold shock, CspA GO:0003676 DC74_RS00115 44a356ad88e3eeb032a8c59341c8a69b 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 23-04-2016 IPR019844 Cold-shock conserved site DC74_RS00115 44a356ad88e3eeb032a8c59341c8a69b 69 Gene3D G3DSA:2.40.50.140 1 66 9.1E-32 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS00115 44a356ad88e3eeb032a8c59341c8a69b 69 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 6.0E-31 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS00115 44a356ad88e3eeb032a8c59341c8a69b 69 SMART SM00357 3 67 9.7E-34 T 23-04-2016 IPR011129 Cold shock protein GO:0003676 DC74_RS00115 44a356ad88e3eeb032a8c59341c8a69b 69 SUPERFAMILY SSF50249 1 67 1.44E-26 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 SUPERFAMILY SSF48179 196 292 6.6E-31 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 Gene3D G3DSA:3.40.50.720 227 432 4.0E-60 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 Gene3D G3DSA:3.40.50.720 5 199 2.7E-67 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 SUPERFAMILY SSF51735 4 187 1.18E-50 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 412 5.5E-125 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 PIRSF PIRSF000124 4 431 1.7E-119 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 PANTHER PTHR11374 4 436 1.4E-182 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 SMART SM00984 315 416 5.9E-30 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 PIRSF PIRSF500134 4 434 1.7E-145 T 23-04-2016 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|UniPathway: UPA00038 DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 180 1.6E-55 T 23-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 SUPERFAMILY SSF52413 306 424 3.53E-28 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 197 287 5.8E-34 T 23-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 315 415 1.7E-23 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 PANTHER PTHR11374:SF18 4 436 1.4E-182 T 23-04-2016 DC74_RS02085 1032972f55cdf09c4c2dba45a7f74741 439 Gene3D G3DSA:1.20.5.100 200 225 8.3E-14 T 23-04-2016 DC74_RS36570 94556b3ee5b210411b0cbeb7cc7f4901 84 ProSitePatterns PS00012 Phosphopantetheine attachment site. 31 46 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS36570 94556b3ee5b210411b0cbeb7cc7f4901 84 Gene3D G3DSA:1.10.1200.10 3 79 4.4E-18 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS36570 94556b3ee5b210411b0cbeb7cc7f4901 84 Pfam PF00550 Phosphopantetheine attachment site 18 70 2.3E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS36570 94556b3ee5b210411b0cbeb7cc7f4901 84 SUPERFAMILY SSF47336 18 79 3.14E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS26430 41b7dcf1dd257f0f0026bc4f84a8244e 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 2.6E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS26430 41b7dcf1dd257f0f0026bc4f84a8244e 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 2.6E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS26430 41b7dcf1dd257f0f0026bc4f84a8244e 253 SMART SM00866 103 243 2.0E-43 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS26430 41b7dcf1dd257f0f0026bc4f84a8244e 253 SUPERFAMILY SSF64288 71 250 3.14E-55 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS26430 41b7dcf1dd257f0f0026bc4f84a8244e 253 Gene3D G3DSA:3.40.1410.10 81 250 9.5E-57 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS26430 41b7dcf1dd257f0f0026bc4f84a8244e 253 Pfam PF07702 UTRA domain 103 243 8.6E-43 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS26430 41b7dcf1dd257f0f0026bc4f84a8244e 253 SMART SM00345 22 83 1.7E-15 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS26430 41b7dcf1dd257f0f0026bc4f84a8244e 253 PANTHER PTHR11751 132 155 5.1E-23 T 23-04-2016 DC74_RS26430 41b7dcf1dd257f0f0026bc4f84a8244e 253 PANTHER PTHR11751 37 86 5.1E-23 T 23-04-2016 DC74_RS26430 41b7dcf1dd257f0f0026bc4f84a8244e 253 Gene3D G3DSA:1.10.10.10 18 80 1.7E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26430 41b7dcf1dd257f0f0026bc4f84a8244e 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 34 83 4.9E-17 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS26430 41b7dcf1dd257f0f0026bc4f84a8244e 253 SUPERFAMILY SSF46785 17 87 2.05E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24565 34398e77283adf19a833f44d789c9314 264 PANTHER PTHR36115 68 263 2.3E-19 T 23-04-2016 DC74_RS24565 34398e77283adf19a833f44d789c9314 264 Pfam PF06271 RDD family 100 257 2.8E-28 T 23-04-2016 IPR010432 RDD DC74_RS08500 a5e0af9eb8130a4bd457eba2d5c760d8 369 PANTHER PTHR41251:SF1 1 304 2.8E-66 T 23-04-2016 DC74_RS08500 a5e0af9eb8130a4bd457eba2d5c760d8 369 SUPERFAMILY SSF100939 2 258 2.75E-39 T 23-04-2016 IPR016194 SPOC-like, C-terminal domain DC74_RS08500 a5e0af9eb8130a4bd457eba2d5c760d8 369 SMART SM00559 53 182 1.0E-26 T 23-04-2016 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: REACT_216|Reactome: REACT_6185 DC74_RS08500 a5e0af9eb8130a4bd457eba2d5c760d8 369 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 174 5.0E-25 T 23-04-2016 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: REACT_216|Reactome: REACT_6185 DC74_RS08500 a5e0af9eb8130a4bd457eba2d5c760d8 369 PANTHER PTHR41251 1 304 2.8E-66 T 23-04-2016 DC74_RS08500 a5e0af9eb8130a4bd457eba2d5c760d8 369 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 256 1.4E-67 T 23-04-2016 IPR009187 Non-homologous end joining protein Ku, prokaryotic type DC74_RS07500 7eec9534ac4569725ef761bceb404f32 146 Pfam PF07883 Cupin domain 42 108 1.3E-20 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS07500 7eec9534ac4569725ef761bceb404f32 146 PIRSF PIRSF016602 1 141 5.2E-57 T 23-04-2016 IPR016672 Polyketide biosynthesis protein CurC, predicted DC74_RS07500 7eec9534ac4569725ef761bceb404f32 146 SUPERFAMILY SSF51182 8 127 2.97E-27 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS07500 7eec9534ac4569725ef761bceb404f32 146 Gene3D G3DSA:2.60.120.10 30 126 4.6E-25 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS27500 20edb552b92573f0fa94cf18070d3620 336 PANTHER PTHR30465:SF56 4 335 1.3E-121 T 23-04-2016 DC74_RS27500 20edb552b92573f0fa94cf18070d3620 336 SUPERFAMILY SSF161098 110 322 1.02E-17 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS27500 20edb552b92573f0fa94cf18070d3620 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 135 334 2.2E-39 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS27500 20edb552b92573f0fa94cf18070d3620 336 Gene3D G3DSA:1.10.3720.10 108 331 1.3E-17 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS27500 20edb552b92573f0fa94cf18070d3620 336 PANTHER PTHR30465 4 335 1.3E-121 T 23-04-2016 DC74_RS04015 9268f753eedf97c4c3f696377df85a94 158 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 77 2.5E-29 T 23-04-2016 IPR025161 Putative transposase IS4/IS5 family DC74_RS04015 9268f753eedf97c4c3f696377df85a94 158 PANTHER PTHR30007 3 133 7.5E-51 T 23-04-2016 DC74_RS04015 9268f753eedf97c4c3f696377df85a94 158 PANTHER PTHR30007:SF18 3 133 7.5E-51 T 23-04-2016 DC74_RS00675 9268f753eedf97c4c3f696377df85a94 158 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 77 2.5E-29 T 23-04-2016 IPR025161 Putative transposase IS4/IS5 family DC74_RS00675 9268f753eedf97c4c3f696377df85a94 158 PANTHER PTHR30007 3 133 7.5E-51 T 23-04-2016 DC74_RS00675 9268f753eedf97c4c3f696377df85a94 158 PANTHER PTHR30007:SF18 3 133 7.5E-51 T 23-04-2016 DC74_RS36205 9268f753eedf97c4c3f696377df85a94 158 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 77 2.5E-29 T 23-04-2016 IPR025161 Putative transposase IS4/IS5 family DC74_RS36205 9268f753eedf97c4c3f696377df85a94 158 PANTHER PTHR30007 3 133 7.5E-51 T 23-04-2016 DC74_RS36205 9268f753eedf97c4c3f696377df85a94 158 PANTHER PTHR30007:SF18 3 133 7.5E-51 T 23-04-2016 DC74_RS04375 9268f753eedf97c4c3f696377df85a94 158 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 6 77 2.5E-29 T 23-04-2016 IPR025161 Putative transposase IS4/IS5 family DC74_RS04375 9268f753eedf97c4c3f696377df85a94 158 PANTHER PTHR30007 3 133 7.5E-51 T 23-04-2016 DC74_RS04375 9268f753eedf97c4c3f696377df85a94 158 PANTHER PTHR30007:SF18 3 133 7.5E-51 T 23-04-2016 DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 Gene3D G3DSA:3.30.2060.10 152 227 1.6E-14 T 23-04-2016 DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 SUPERFAMILY SSF52540 17 370 1.54E-69 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 170 1107 0.0 T 23-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 Gene3D G3DSA:3.40.50.300 829 983 3.8E-32 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 SUPERFAMILY SSF52540 809 1017 2.01E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 SUPERFAMILY SSF143517 1021 1176 1.31E-32 T 23-04-2016 DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 Pfam PF00271 Helicase conserved C-terminal domain 837 936 2.7E-14 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 SMART SM00982 1034 1132 5.5E-37 T 23-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 SMART SM00490 853 937 5.5E-15 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 SUPERFAMILY SSF141259 496 575 2.35E-17 T 23-04-2016 IPR003711 CarD-like/TRCF domain DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 SMART SM00487 627 826 3.5E-31 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 Gene3D G3DSA:3.40.50.300 615 813 6.5E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 PANTHER PTHR14025:SF21 411 1176 0.0 T 23-04-2016 DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 PANTHER PTHR14025 411 1176 0.0 T 23-04-2016 DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 44 1127 28.597 T 23-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 SUPERFAMILY SSF52540 552 810 1.98E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 Pfam PF00270 DEAD/DEAH box helicase 634 794 9.1E-17 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 SMART SM01058 502 603 4.5E-46 T 23-04-2016 IPR003711 CarD-like/TRCF domain DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 Pfam PF02559 CarD-like/TRCF domain 503 602 4.8E-30 T 23-04-2016 IPR003711 CarD-like/TRCF domain DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 SUPERFAMILY SSF52540 392 485 1.65E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS17445 0fe7df6ee50c13235d9edfd815d2dc82 1178 Pfam PF03461 TRCF domain 1035 1116 2.4E-24 T 23-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 DC74_RS10280 458bd7ed853e8a9997a06bee806f3229 330 PANTHER PTHR34580 1 329 4.6E-67 T 23-04-2016 DC74_RS10280 458bd7ed853e8a9997a06bee806f3229 330 Pfam PF13280 WYL domain 162 327 1.9E-31 T 23-04-2016 IPR026881 WYL domain DC74_RS10280 458bd7ed853e8a9997a06bee806f3229 330 PANTHER PTHR34580:SF3 1 329 4.6E-67 T 23-04-2016 DC74_RS08315 c63b24a4738a8735500849bf6261c6bc 286 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 184 7.2E-21 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS08315 c63b24a4738a8735500849bf6261c6bc 286 PANTHER PTHR30383 5 196 1.8E-31 T 23-04-2016 DC74_RS08315 c63b24a4738a8735500849bf6261c6bc 286 SUPERFAMILY SSF52266 5 193 1.24E-31 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS08315 c63b24a4738a8735500849bf6261c6bc 286 Gene3D G3DSA:3.40.50.1110 5 193 1.8E-26 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS08315 c63b24a4738a8735500849bf6261c6bc 286 PANTHER PTHR30383:SF8 5 196 1.8E-31 T 23-04-2016 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 SUPERFAMILY SSF51905 5 175 1.59E-53 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 SUPERFAMILY SSF51905 278 385 1.59E-53 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 Gene3D G3DSA:3.40.50.720 23 64 1.5E-6 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 Pfam PF01494 FAD binding domain 5 346 6.9E-74 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 Gene3D G3DSA:3.50.50.60 8 22 7.9E-5 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 Gene3D G3DSA:3.50.50.60 96 149 7.9E-5 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 Gene3D G3DSA:3.30.9.10 150 303 1.6E-59 T 23-04-2016 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 SUPERFAMILY SSF54373 178 279 5.49E-35 T 23-04-2016 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 1.1E-28 T 23-04-2016 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 332 1.1E-28 T 23-04-2016 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.1E-28 T 23-04-2016 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 1.1E-28 T 23-04-2016 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 1.1E-28 T 23-04-2016 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 PANTHER PTHR13789 6 393 3.8E-179 T 23-04-2016 DC74_RS30915 c23da93e766986b1f4d8049bae35ab99 395 PANTHER PTHR13789:SF192 6 393 3.8E-179 T 23-04-2016 DC74_RS34695 e224d06d6291c93c30ac148da401f50e 226 Gene3D G3DSA:1.10.10.10 146 224 8.9E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34695 e224d06d6291c93c30ac148da401f50e 226 SMART SM00862 147 223 8.7E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS34695 e224d06d6291c93c30ac148da401f50e 226 Pfam PF00072 Response regulator receiver domain 4 112 6.7E-28 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS34695 e224d06d6291c93c30ac148da401f50e 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 1.1E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS34695 e224d06d6291c93c30ac148da401f50e 226 PANTHER PTHR26402:SF50 2 225 2.4E-87 T 23-04-2016 DC74_RS34695 e224d06d6291c93c30ac148da401f50e 226 SMART SM00448 2 112 5.8E-44 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS34695 e224d06d6291c93c30ac148da401f50e 226 SUPERFAMILY SSF52172 1 124 2.99E-41 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS34695 e224d06d6291c93c30ac148da401f50e 226 Gene3D G3DSA:3.40.50.2300 1 145 1.1E-41 T 23-04-2016 DC74_RS34695 e224d06d6291c93c30ac148da401f50e 226 PANTHER PTHR26402 2 225 2.4E-87 T 23-04-2016 DC74_RS34695 e224d06d6291c93c30ac148da401f50e 226 SUPERFAMILY SSF46894 131 223 5.39E-25 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS32425 912185652b34d2f9822b92abcffacfe2 258 PANTHER PTHR40036:SF1 45 232 5.7E-14 T 23-04-2016 DC74_RS32425 912185652b34d2f9822b92abcffacfe2 258 PANTHER PTHR40036 45 232 5.7E-14 T 23-04-2016 DC74_RS32425 912185652b34d2f9822b92abcffacfe2 258 SUPERFAMILY SSF53335 143 234 1.54E-6 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS32425 912185652b34d2f9822b92abcffacfe2 258 Gene3D G3DSA:3.40.50.150 145 234 2.2E-7 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS32425 912185652b34d2f9822b92abcffacfe2 258 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 68 232 4.1E-6 T 23-04-2016 IPR008884 Macrocin-O-methyltransferase DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 PANTHER PTHR23501 14 537 7.6E-161 T 23-04-2016 DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 Pfam PF07690 Major Facilitator Superfamily 34 430 5.0E-57 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 Gene3D G3DSA:1.20.1250.20 501 521 1.0E-25 T 23-04-2016 DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 Gene3D G3DSA:1.20.1250.20 284 444 1.0E-25 T 23-04-2016 DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 Gene3D G3DSA:1.20.1250.20 24 215 1.0E-32 T 23-04-2016 DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 SUPERFAMILY SSF103473 269 440 7.85E-75 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 SUPERFAMILY SSF103473 496 521 7.85E-75 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 SUPERFAMILY SSF103473 16 217 7.85E-75 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 PANTHER PTHR23501:SF65 14 537 7.6E-161 T 23-04-2016 DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 PRINTS PR01036 Tetracycline resistance protein TetB signature 421 440 9.5E-7 T 23-04-2016 DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 PRINTS PR01036 Tetracycline resistance protein TetB signature 223 241 9.5E-7 T 23-04-2016 DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 PRINTS PR01036 Tetracycline resistance protein TetB signature 158 182 9.5E-7 T 23-04-2016 DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 PRINTS PR01036 Tetracycline resistance protein TetB signature 128 148 9.5E-7 T 23-04-2016 DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 PRINTS PR01036 Tetracycline resistance protein TetB signature 33 57 9.5E-7 T 23-04-2016 DC74_RS13330 5fc09816451c24fb561aae3e9301a777 543 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 30 452 1.3E-82 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS02090 1b8540504bd11748c1f7a6bf4e253c61 253 Gene3D G3DSA:1.10.10.60 4 60 2.8E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02090 1b8540504bd11748c1f7a6bf4e253c61 253 PANTHER PTHR30055 1 217 4.3E-14 T 23-04-2016 DC74_RS02090 1b8540504bd11748c1f7a6bf4e253c61 253 SUPERFAMILY SSF48498 85 184 1.4E-14 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS02090 1b8540504bd11748c1f7a6bf4e253c61 253 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 5.6E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS02090 1b8540504bd11748c1f7a6bf4e253c61 253 SUPERFAMILY SSF46689 4 62 6.31E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02090 1b8540504bd11748c1f7a6bf4e253c61 253 Gene3D G3DSA:1.10.357.10 67 184 2.8E-17 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS28175 26fcf8778e82584134a7725d586afede 387 Pfam PF02481 DNA recombination-mediator protein A 83 288 4.2E-68 T 23-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 DC74_RS28175 26fcf8778e82584134a7725d586afede 387 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 83 295 3.0E-63 T 23-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 DC74_RS28175 26fcf8778e82584134a7725d586afede 387 Gene3D G3DSA:3.40.50.450 123 296 1.4E-16 T 23-04-2016 DC74_RS28175 26fcf8778e82584134a7725d586afede 387 PANTHER PTHR32039 75 376 7.4E-74 T 23-04-2016 DC74_RS28175 26fcf8778e82584134a7725d586afede 387 SUPERFAMILY SSF102405 90 297 2.14E-38 T 23-04-2016 DC74_RS28175 26fcf8778e82584134a7725d586afede 387 Gene3D G3DSA:1.10.10.10 323 375 5.1E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28175 26fcf8778e82584134a7725d586afede 387 PANTHER PTHR32039:SF8 75 376 7.4E-74 T 23-04-2016 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PANTHER PTHR11670:SF38 1 307 8.0E-252 T 23-04-2016 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PANTHER PTHR11670:SF38 327 460 8.0E-252 T 23-04-2016 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 6.0E-149 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 23-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 Gene3D G3DSA:3.30.499.10 2 152 1.8E-21 T 23-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PANTHER PTHR11670 1 307 8.0E-252 T 23-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PANTHER PTHR11670 327 460 8.0E-252 T 23-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 58.867 T 23-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PRINTS PR00415 Aconitase family signature 133 148 6.5E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PRINTS PR00415 Aconitase family signature 343 354 6.5E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PRINTS PR00415 Aconitase family signature 108 116 6.5E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PRINTS PR00415 Aconitase family signature 195 208 6.5E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PRINTS PR00415 Aconitase family signature 82 95 6.5E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PRINTS PR00415 Aconitase family signature 286 300 6.5E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PRINTS PR00415 Aconitase family signature 119 132 6.5E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PRINTS PR00415 Aconitase family signature 399 412 6.5E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 PRINTS PR00415 Aconitase family signature 209 222 6.5E-47 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 23-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 Gene3D G3DSA:3.40.1060.10 153 288 2.0E-39 T 23-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 Gene3D G3DSA:3.30.499.10 322 466 1.4E-56 T 23-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 SUPERFAMILY SSF53732 1 465 4.19E-159 T 23-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS27905 744b811f3cea1afe1c3db916cc2c652b 476 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 2.1E-221 T 23-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS08945 550184f5c0f90dbeca6e20ecc7856136 144 Gene3D G3DSA:1.10.10.10 9 80 3.9E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08945 550184f5c0f90dbeca6e20ecc7856136 144 PANTHER PTHR33169:SF4 8 128 2.4E-14 T 23-04-2016 DC74_RS08945 550184f5c0f90dbeca6e20ecc7856136 144 Pfam PF03551 Transcriptional regulator PadR-like family 9 76 3.0E-8 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS08945 550184f5c0f90dbeca6e20ecc7856136 144 SUPERFAMILY SSF46785 8 126 2.73E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08945 550184f5c0f90dbeca6e20ecc7856136 144 PANTHER PTHR33169 8 128 2.4E-14 T 23-04-2016 DC74_RS06120 082335ffc42dc319847835a3ba3777ac 221 Gene3D G3DSA:1.20.120.450 4 67 1.2E-7 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS06120 082335ffc42dc319847835a3ba3777ac 221 SUPERFAMILY SSF109854 2 151 2.2E-12 T 23-04-2016 DC74_RS06120 082335ffc42dc319847835a3ba3777ac 221 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 6 149 1.1E-22 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS14665 21ffe4a004d135e9e4e580ab6188f1df 262 PANTHER PTHR30269:SF0 5 262 2.0E-73 T 23-04-2016 DC74_RS14665 21ffe4a004d135e9e4e580ab6188f1df 262 Pfam PF01925 Sulfite exporter TauE/SafE 14 253 1.9E-35 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 DC74_RS14665 21ffe4a004d135e9e4e580ab6188f1df 262 PANTHER PTHR30269 5 262 2.0E-73 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 SUPERFAMILY SSF51445 463 746 9.97E-105 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 SUPERFAMILY SSF51445 9 411 9.97E-105 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 Gene3D G3DSA:3.20.20.80 513 552 1.7E-66 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 Gene3D G3DSA:3.20.20.80 663 775 1.7E-66 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 Gene3D G3DSA:3.20.20.80 233 305 1.7E-66 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 Gene3D G3DSA:3.20.20.80 9 98 1.7E-66 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 Gene3D G3DSA:3.30.1590.10 99 217 8.5E-34 T 23-04-2016 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 9 837 3.0E-253 T 23-04-2016 IPR012767 Malto-oligosyltrehalose synthase MetaCyc: PWY-2661 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 PANTHER PTHR10357 655 814 1.6E-129 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 PANTHER PTHR10357 185 340 1.6E-129 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 PANTHER PTHR10357 23 132 1.6E-129 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 SMART SM00642 9 739 2.1E-6 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 PANTHER PTHR10357:SF166 655 814 1.6E-129 T 23-04-2016 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 PANTHER PTHR10357:SF166 185 340 1.6E-129 T 23-04-2016 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 PANTHER PTHR10357:SF166 23 132 1.6E-129 T 23-04-2016 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 Gene3D G3DSA:1.10.10.470 553 648 4.4E-15 T 23-04-2016 IPR013797 Maltooligosyl trehalose synthase, N-terminal MetaCyc: PWY-2661 DC74_RS29970 73b9862ef540fd490faa8636c46a3dbd 838 Pfam PF00128 Alpha amylase, catalytic domain 31 100 2.1E-11 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS12050 e1419e034507fbe349670d858813ceab 277 PANTHER PTHR10108 25 184 1.7E-30 T 23-04-2016 DC74_RS12050 e1419e034507fbe349670d858813ceab 277 PANTHER PTHR10108 201 260 1.7E-30 T 23-04-2016 DC74_RS12050 e1419e034507fbe349670d858813ceab 277 Gene3D G3DSA:3.40.50.150 26 261 7.6E-33 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS12050 e1419e034507fbe349670d858813ceab 277 Pfam PF08241 Methyltransferase domain 77 174 2.5E-19 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS12050 e1419e034507fbe349670d858813ceab 277 PANTHER PTHR10108:SF779 25 184 1.7E-30 T 23-04-2016 DC74_RS12050 e1419e034507fbe349670d858813ceab 277 PANTHER PTHR10108:SF779 201 260 1.7E-30 T 23-04-2016 DC74_RS12050 e1419e034507fbe349670d858813ceab 277 SUPERFAMILY SSF53335 26 249 1.59E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14520 b179359925c289373088619b66485778 134 Pfam PF04343 Protein of unknown function, DUF488 40 111 5.9E-5 T 23-04-2016 IPR007438 Protein of unknown function DUF488 DC74_RS23795 9167de0be824d4f6207f57a6296832aa 333 PANTHER PTHR11732:SF150 1 333 7.9E-123 T 23-04-2016 DC74_RS23795 9167de0be824d4f6207f57a6296832aa 333 PANTHER PTHR11732 1 333 7.9E-123 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS23795 9167de0be824d4f6207f57a6296832aa 333 Pfam PF00248 Aldo/keto reductase family 15 319 3.2E-67 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS23795 9167de0be824d4f6207f57a6296832aa 333 SUPERFAMILY SSF51430 1 322 8.9E-94 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS23795 9167de0be824d4f6207f57a6296832aa 333 Gene3D G3DSA:3.20.20.100 1 321 1.6E-93 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS32500 d64351baa093cd1210afe358b88adad1 223 PANTHER PTHR34979 1 223 1.2E-30 T 23-04-2016 DC74_RS32500 d64351baa093cd1210afe358b88adad1 223 Pfam PF03591 AzlC protein 10 146 6.5E-33 T 23-04-2016 IPR011606 Branched-chain amino acid transport, permease DC74_RS19475 59ae5f34e9e3a8235ebc78e0730a317a 331 PIRSF PIRSF016753 32 331 1.4E-104 T 23-04-2016 IPR016676 Phospholipid/glycerol acyltransferase, predicted DC74_RS19475 59ae5f34e9e3a8235ebc78e0730a317a 331 SMART SM00563 118 237 1.6E-17 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS19475 59ae5f34e9e3a8235ebc78e0730a317a 331 PANTHER PTHR22753 52 329 4.0E-152 T 23-04-2016 DC74_RS19475 59ae5f34e9e3a8235ebc78e0730a317a 331 Pfam PF01553 Acyltransferase 103 234 4.3E-18 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS19475 59ae5f34e9e3a8235ebc78e0730a317a 331 PANTHER PTHR22753:SF11 52 329 4.0E-152 T 23-04-2016 DC74_RS19475 59ae5f34e9e3a8235ebc78e0730a317a 331 Gene3D G3DSA:3.40.1130.10 88 243 5.1E-7 T 23-04-2016 DC74_RS19475 59ae5f34e9e3a8235ebc78e0730a317a 331 SUPERFAMILY SSF69593 91 322 2.22E-35 T 23-04-2016 DC74_RS16960 5a9eb3fecd221f73e256ea235cd234f5 60 PANTHER PTHR33505 1 58 5.4E-14 T 23-04-2016 DC74_RS16960 5a9eb3fecd221f73e256ea235cd234f5 60 Pfam PF03966 Trm112p-like protein 6 47 2.1E-6 T 23-04-2016 IPR005651 Uncharacterised protein family UPF0434/Trm112 DC74_RS16960 5a9eb3fecd221f73e256ea235cd234f5 60 Gene3D G3DSA:2.20.25.10 10 58 4.8E-20 T 23-04-2016 DC74_RS16960 5a9eb3fecd221f73e256ea235cd234f5 60 SUPERFAMILY SSF158997 2 58 1.02E-14 T 23-04-2016 DC74_RS35120 330eba0bc52a8bca1dc0017f01c903c7 454 PRINTS PR00359 B-class P450 signature 207 229 7.2E-15 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35120 330eba0bc52a8bca1dc0017f01c903c7 454 PRINTS PR00359 B-class P450 signature 303 330 7.2E-15 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35120 330eba0bc52a8bca1dc0017f01c903c7 454 PRINTS PR00359 B-class P450 signature 111 122 7.2E-15 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35120 330eba0bc52a8bca1dc0017f01c903c7 454 PRINTS PR00359 B-class P450 signature 157 173 7.2E-15 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS35120 330eba0bc52a8bca1dc0017f01c903c7 454 PANTHER PTHR11712 37 410 1.3E-45 T 23-04-2016 DC74_RS35120 330eba0bc52a8bca1dc0017f01c903c7 454 PANTHER PTHR11712:SF282 37 410 1.3E-45 T 23-04-2016 DC74_RS35120 330eba0bc52a8bca1dc0017f01c903c7 454 SUPERFAMILY SSF48264 30 405 6.55E-56 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS35120 330eba0bc52a8bca1dc0017f01c903c7 454 Gene3D G3DSA:1.10.630.10 24 411 4.4E-78 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS19105 fb965fe5e23d589f05f7c15bf110d301 399 PANTHER PTHR22976:SF29 1 384 9.5E-199 T 23-04-2016 DC74_RS19105 fb965fe5e23d589f05f7c15bf110d301 399 PIRSF PIRSF004762 1 373 1.1E-108 T 23-04-2016 IPR005244 FO synthase, subunit 2-like GO:0016765|GO:0051188|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 DC74_RS19105 fb965fe5e23d589f05f7c15bf110d301 399 PANTHER PTHR22976 1 384 9.5E-199 T 23-04-2016 DC74_RS19105 fb965fe5e23d589f05f7c15bf110d301 399 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 19 360 3.6E-141 T 23-04-2016 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 DC74_RS19105 fb965fe5e23d589f05f7c15bf110d301 399 Pfam PF04055 Radical SAM superfamily 65 238 3.0E-15 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS19105 fb965fe5e23d589f05f7c15bf110d301 399 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 57 360 2.4E-105 T 23-04-2016 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198|UniPathway: UPA00072 DC74_RS19105 fb965fe5e23d589f05f7c15bf110d301 399 SUPERFAMILY SSF102114 17 352 1.06E-51 T 23-04-2016 DC74_RS19105 fb965fe5e23d589f05f7c15bf110d301 399 Gene3D G3DSA:3.20.20.70 18 353 6.4E-65 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS19105 fb965fe5e23d589f05f7c15bf110d301 399 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 17 363 51.111 T 23-04-2016 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 DC74_RS34135 a1f727f75467de836dba6cbedac4519c 239 SUPERFAMILY SSF144091 32 211 9.55E-9 T 23-04-2016 DC74_RS11685 f2e5fb19f62ee687c0f3c6d51eb2ff22 262 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 3 222 1.1E-31 T 23-04-2016 DC74_RS11685 f2e5fb19f62ee687c0f3c6d51eb2ff22 262 PANTHER PTHR37468 3 259 4.7E-55 T 23-04-2016 DC74_RS03745 60b0f2bc204fcedc3fb2e01935822bcd 425 SMART SM01260 55 423 6.5E-9 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS03745 60b0f2bc204fcedc3fb2e01935822bcd 425 Pfam PF05147 Lanthionine synthetase C-like protein 126 410 3.4E-19 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS03745 60b0f2bc204fcedc3fb2e01935822bcd 425 PRINTS PR01950 LanC-like protein superfamily signature 215 231 1.2E-11 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS03745 60b0f2bc204fcedc3fb2e01935822bcd 425 PRINTS PR01950 LanC-like protein superfamily signature 288 308 1.2E-11 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS03745 60b0f2bc204fcedc3fb2e01935822bcd 425 PRINTS PR01950 LanC-like protein superfamily signature 154 169 1.2E-11 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS03745 60b0f2bc204fcedc3fb2e01935822bcd 425 PRINTS PR01950 LanC-like protein superfamily signature 394 411 1.2E-11 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS03745 60b0f2bc204fcedc3fb2e01935822bcd 425 SUPERFAMILY SSF158745 97 415 2.48E-30 T 23-04-2016 DC74_RS03745 60b0f2bc204fcedc3fb2e01935822bcd 425 PRINTS PR01955 Frankia sp. LanC-like protein signature 212 236 1.6E-16 T 23-04-2016 IPR020434 LanC-like protein DC74_RS03745 60b0f2bc204fcedc3fb2e01935822bcd 425 PRINTS PR01955 Frankia sp. LanC-like protein signature 395 412 1.6E-16 T 23-04-2016 IPR020434 LanC-like protein DC74_RS03745 60b0f2bc204fcedc3fb2e01935822bcd 425 PRINTS PR01955 Frankia sp. LanC-like protein signature 153 169 1.6E-16 T 23-04-2016 IPR020434 LanC-like protein DC74_RS03745 60b0f2bc204fcedc3fb2e01935822bcd 425 PRINTS PR01955 Frankia sp. LanC-like protein signature 288 311 1.6E-16 T 23-04-2016 IPR020434 LanC-like protein DC74_RS00280 dc9b3901a80aa6157d6824652dd6bcc3 480 SUPERFAMILY SSF47413 27 84 7.51E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS00280 dc9b3901a80aa6157d6824652dd6bcc3 480 Gene3D G3DSA:1.10.260.40 38 82 3.4E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS00280 dc9b3901a80aa6157d6824652dd6bcc3 480 SMART SM00530 17 86 4.5E-5 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS00280 dc9b3901a80aa6157d6824652dd6bcc3 480 Gene3D G3DSA:1.25.40.10 404 455 0.001 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS00280 dc9b3901a80aa6157d6824652dd6bcc3 480 Gene3D G3DSA:1.25.40.10 235 349 0.001 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS00280 dc9b3901a80aa6157d6824652dd6bcc3 480 Pfam PF13560 Helix-turn-helix domain 29 86 1.2E-6 T 23-04-2016 DC74_RS38500 eb05cd194b082ea6ba15d75861844364 194 Pfam PF13977 Bacterial transcriptional repressor 77 189 4.9E-16 T 23-04-2016 DC74_RS38500 eb05cd194b082ea6ba15d75861844364 194 PANTHER PTHR30055 4 190 2.9E-21 T 23-04-2016 DC74_RS38500 eb05cd194b082ea6ba15d75861844364 194 SUPERFAMILY SSF48498 76 187 1.61E-19 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS38500 eb05cd194b082ea6ba15d75861844364 194 SUPERFAMILY SSF46689 4 79 7.7E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS38500 eb05cd194b082ea6ba15d75861844364 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 8.4E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS38500 eb05cd194b082ea6ba15d75861844364 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 8.4E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS38500 eb05cd194b082ea6ba15d75861844364 194 Gene3D G3DSA:1.10.357.10 3 190 3.7E-33 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS38500 eb05cd194b082ea6ba15d75861844364 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 51 6.9E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS35150 3f01681d58d4981fd613127117dd8ed6 171 Pfam PF00583 Acetyltransferase (GNAT) family 74 151 1.0E-8 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS35150 3f01681d58d4981fd613127117dd8ed6 171 Gene3D G3DSA:3.40.630.30 4 156 2.3E-19 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS35150 3f01681d58d4981fd613127117dd8ed6 171 SUPERFAMILY SSF55729 2 157 1.24E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS11915 5a7b95289bb528f768c26c28624ac2c5 218 SMART SM00849 32 197 2.1E-29 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS11915 5a7b95289bb528f768c26c28624ac2c5 218 Pfam PF00753 Metallo-beta-lactamase superfamily 29 197 1.3E-11 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS11915 5a7b95289bb528f768c26c28624ac2c5 218 SUPERFAMILY SSF56281 22 214 7.58E-44 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS11915 5a7b95289bb528f768c26c28624ac2c5 218 PANTHER PTHR11935 17 216 1.6E-108 T 23-04-2016 DC74_RS11915 5a7b95289bb528f768c26c28624ac2c5 218 Gene3D G3DSA:3.60.15.10 19 216 6.6E-48 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS11915 5a7b95289bb528f768c26c28624ac2c5 218 PANTHER PTHR11935:SF89 17 216 1.6E-108 T 23-04-2016 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 SMART SM00996 9 484 0.0 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 9 484 3.7E-150 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 Gene3D G3DSA:3.40.50.1480 8 244 4.3E-150 T 23-04-2016 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 Gene3D G3DSA:3.40.50.1480 406 485 4.3E-150 T 23-04-2016 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 PANTHER PTHR23420 7 155 0.0 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 PANTHER PTHR23420 193 485 0.0 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 5 477 50.106 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 SMART SM00997 243 405 3.6E-110 T 23-04-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 Gene3D G3DSA:3.40.50.720 245 404 2.0E-51 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 SUPERFAMILY SSF51735 243 405 1.64E-77 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 PANTHER PTHR23420:SF6 7 155 0.0 T 23-04-2016 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 PANTHER PTHR23420:SF6 193 485 0.0 T 23-04-2016 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 265 281 - T 23-04-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 PIRSF PIRSF001109 1 485 3.7E-196 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 81 95 - T 23-04-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 243 405 5.0E-83 T 23-04-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 10 477 9.3E-193 T 23-04-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 SUPERFAMILY SSF52283 406 485 2.61E-116 T 23-04-2016 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 SUPERFAMILY SSF52283 8 157 2.61E-116 T 23-04-2016 DC74_RS16940 70385cc8018a8b9c9c5387f0c5cde0e6 485 SUPERFAMILY SSF52283 195 242 2.61E-116 T 23-04-2016 DC74_RS34680 2f700bba1fc1ddaed105140e18fe5e42 193 Gene3D G3DSA:1.10.357.10 66 189 7.7E-26 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS34680 2f700bba1fc1ddaed105140e18fe5e42 193 SUPERFAMILY SSF46689 6 79 2.46E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS34680 2f700bba1fc1ddaed105140e18fe5e42 193 Gene3D G3DSA:1.10.10.60 4 65 2.0E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS34680 2f700bba1fc1ddaed105140e18fe5e42 193 PANTHER PTHR30055 1 191 8.6E-125 T 23-04-2016 DC74_RS34680 2f700bba1fc1ddaed105140e18fe5e42 193 Pfam PF13305 WHG domain 92 173 4.3E-14 T 23-04-2016 IPR025996 WHG domain DC74_RS34680 2f700bba1fc1ddaed105140e18fe5e42 193 PANTHER PTHR30055:SF77 1 191 8.6E-125 T 23-04-2016 DC74_RS34680 2f700bba1fc1ddaed105140e18fe5e42 193 SUPERFAMILY SSF48498 85 176 5.56E-20 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS34680 2f700bba1fc1ddaed105140e18fe5e42 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.9E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34680 2f700bba1fc1ddaed105140e18fe5e42 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.6E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34680 2f700bba1fc1ddaed105140e18fe5e42 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.6E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS30805 664d2ca74222c0774579a2e50fce7e46 81 Gene3D G3DSA:1.10.10.10 26 79 1.1E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13005 27785cd4a7af5296cf11fffc1b9c8d1d 261 PANTHER PTHR31088:SF0 1 261 5.6E-76 T 23-04-2016 DC74_RS13005 27785cd4a7af5296cf11fffc1b9c8d1d 261 PANTHER PTHR31088 1 261 5.6E-76 T 23-04-2016 DC74_RS13005 27785cd4a7af5296cf11fffc1b9c8d1d 261 Pfam PF04012 PspA/IM30 family 2 227 1.2E-29 T 23-04-2016 IPR007157 PspA/IM30 DC74_RS28350 711b13547874a4c4b5d9493c36541db6 230 Gene3D G3DSA:1.20.144.10 6 214 1.0E-16 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS28350 711b13547874a4c4b5d9493c36541db6 230 Pfam PF01569 PAP2 superfamily 110 205 6.3E-11 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS28350 711b13547874a4c4b5d9493c36541db6 230 SUPERFAMILY SSF48317 168 217 1.66E-18 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS28350 711b13547874a4c4b5d9493c36541db6 230 SUPERFAMILY SSF48317 2 135 1.66E-18 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS03355 0090be9d3f3e9eded80c03e5aa5419c0 163 Pfam PF11188 Protein of unknown function (DUF2975) 40 163 1.6E-21 T 23-04-2016 IPR021354 Protein of unknown function DUF2975 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 Gene3D G3DSA:3.40.228.10 145 323 3.7E-50 T 23-04-2016 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 PANTHER PTHR11615:SF119 11 545 7.1E-213 T 23-04-2016 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 PANTHER PTHR11615:SF119 565 718 7.1E-213 T 23-04-2016 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 SUPERFAMILY SSF53706 11 607 2.88E-163 T 23-04-2016 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 Gene3D G3DSA:2.20.25.90 11 64 9.1E-17 T 23-04-2016 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 Gene3D G3DSA:2.40.40.20 555 717 1.1E-55 T 23-04-2016 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 Pfam PF00384 Molybdopterin oxidoreductase 69 495 1.4E-68 T 23-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 SUPERFAMILY SSF50692 566 717 9.95E-51 T 23-04-2016 IPR009010 Aspartate decarboxylase-like domain DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 10 63 3.6E-13 T 23-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 Pfam PF01568 Molydopterin dinucleotide binding domain 606 712 3.3E-34 T 23-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 SMART SM00926 9 66 2.5E-12 T 23-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 Gene3D G3DSA:3.40.50.740 324 348 7.3E-65 T 23-04-2016 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 Gene3D G3DSA:3.40.50.740 383 533 7.3E-65 T 23-04-2016 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 Gene3D G3DSA:3.40.50.740 69 143 7.3E-65 T 23-04-2016 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 PANTHER PTHR11615 11 545 7.1E-213 T 23-04-2016 DC74_RS14625 22e3b82f7fe2e0dcbe365058b1feea47 720 PANTHER PTHR11615 565 718 7.1E-213 T 23-04-2016 DC74_RS40280 f9a216d3aebb2196deb3b4e747d08adb 591 Gene3D G3DSA:3.30.200.20 12 95 7.5E-15 T 23-04-2016 DC74_RS40280 f9a216d3aebb2196deb3b4e747d08adb 591 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS40280 f9a216d3aebb2196deb3b4e747d08adb 591 PANTHER PTHR24362:SF247 11 359 3.3E-71 T 23-04-2016 DC74_RS40280 f9a216d3aebb2196deb3b4e747d08adb 591 SUPERFAMILY SSF56112 12 265 3.86E-64 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS40280 f9a216d3aebb2196deb3b4e747d08adb 591 Pfam PF00069 Protein kinase domain 17 262 5.8E-40 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS40280 f9a216d3aebb2196deb3b4e747d08adb 591 SMART SM00220 16 265 1.1E-45 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS40280 f9a216d3aebb2196deb3b4e747d08adb 591 PANTHER PTHR24362 11 359 3.3E-71 T 23-04-2016 DC74_RS40280 f9a216d3aebb2196deb3b4e747d08adb 591 Gene3D G3DSA:1.10.510.10 101 289 2.6E-41 T 23-04-2016 DC74_RS02905 c5bba289d6a9d29c7177f3e58b090d49 229 Gene3D G3DSA:3.90.870.10 10 205 8.3E-12 T 23-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain DC74_RS02905 c5bba289d6a9d29c7177f3e58b090d49 229 SUPERFAMILY SSF55821 14 209 1.43E-10 T 23-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain DC74_RS02905 c5bba289d6a9d29c7177f3e58b090d49 229 Pfam PF01300 Telomere recombination 22 201 1.5E-7 T 23-04-2016 IPR006070 YrdC-like domain GO:0003725 DC74_RS10440 21f4565c05ace44b38725a8cdd0ab3ae 350 PANTHER PTHR32196:SF9 40 316 2.3E-23 T 23-04-2016 DC74_RS10440 21f4565c05ace44b38725a8cdd0ab3ae 350 Pfam PF13407 Periplasmic binding protein domain 41 302 8.4E-44 T 23-04-2016 IPR025997 Periplasmic binding protein DC74_RS10440 21f4565c05ace44b38725a8cdd0ab3ae 350 Gene3D G3DSA:3.40.50.2300 158 338 4.2E-32 T 23-04-2016 DC74_RS10440 21f4565c05ace44b38725a8cdd0ab3ae 350 PANTHER PTHR32196 40 316 2.3E-23 T 23-04-2016 DC74_RS10440 21f4565c05ace44b38725a8cdd0ab3ae 350 Gene3D G3DSA:3.40.50.2300 40 157 3.4E-22 T 23-04-2016 DC74_RS10440 21f4565c05ace44b38725a8cdd0ab3ae 350 SUPERFAMILY SSF53822 40 338 2.19E-51 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS22330 3496db3522020bb760bfdaef2a347c57 382 SMART SM00833 238 354 1.9E-35 T 23-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal DC74_RS22330 3496db3522020bb760bfdaef2a347c57 382 PANTHER PTHR13748:SF4 64 311 1.0E-64 T 23-04-2016 DC74_RS22330 3496db3522020bb760bfdaef2a347c57 382 PANTHER PTHR13748:SF4 328 368 1.0E-64 T 23-04-2016 DC74_RS22330 3496db3522020bb760bfdaef2a347c57 382 PANTHER PTHR13748 64 311 1.0E-64 T 23-04-2016 DC74_RS22330 3496db3522020bb760bfdaef2a347c57 382 PANTHER PTHR13748 328 368 1.0E-64 T 23-04-2016 DC74_RS22330 3496db3522020bb760bfdaef2a347c57 382 Gene3D G3DSA:3.40.50.300 64 204 3.0E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22330 3496db3522020bb760bfdaef2a347c57 382 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 64 187 3.5E-6 T 23-04-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain DC74_RS22330 3496db3522020bb760bfdaef2a347c57 382 SUPERFAMILY SSF90002 239 301 1.83E-8 T 23-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal DC74_RS22330 3496db3522020bb760bfdaef2a347c57 382 SUPERFAMILY SSF90002 328 354 1.83E-8 T 23-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal DC74_RS22330 3496db3522020bb760bfdaef2a347c57 382 Gene3D G3DSA:3.30.1220.10 231 354 1.3E-6 T 23-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal DC74_RS22330 3496db3522020bb760bfdaef2a347c57 382 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 239 354 4.0E-18 T 23-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal DC74_RS37860 32bb57bdc2f46d60a68cd72c177c897b 373 SUPERFAMILY SSF51055 323 373 1.59E-13 T 23-04-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 DC74_RS37860 32bb57bdc2f46d60a68cd72c177c897b 373 Gene3D G3DSA:2.10.10.20 324 373 3.7E-17 T 23-04-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 DC74_RS37860 32bb57bdc2f46d60a68cd72c177c897b 373 PANTHER PTHR11177 34 267 1.0E-16 T 23-04-2016 DC74_RS37860 32bb57bdc2f46d60a68cd72c177c897b 373 PANTHER PTHR11177:SF203 34 267 1.0E-16 T 23-04-2016 DC74_RS37860 32bb57bdc2f46d60a68cd72c177c897b 373 Gene3D G3DSA:3.20.20.80 57 268 7.5E-13 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS37860 32bb57bdc2f46d60a68cd72c177c897b 373 SMART SM00495 326 370 3.2E-12 T 23-04-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 DC74_RS37860 32bb57bdc2f46d60a68cd72c177c897b 373 SUPERFAMILY SSF51445 24 268 6.68E-18 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS37860 32bb57bdc2f46d60a68cd72c177c897b 373 Pfam PF02839 Carbohydrate binding domain 327 367 3.2E-11 T 23-04-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 310 41.091 T 23-04-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 Gene3D G3DSA:3.20.190.10 2 156 1.2E-34 T 23-04-2016 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 SMART SM01232 169 261 2.1E-42 T 23-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 SUPERFAMILY SSF81624 2 178 5.1E-31 T 23-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 ProSitePatterns PS01242 Zinc finger FPG-type signature. 285 309 - T 23-04-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 Gene3D G3DSA:1.10.8.50 171 310 2.1E-47 T 23-04-2016 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 SUPERFAMILY SSF57716 261 310 9.41E-17 T 23-04-2016 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 148 8.3E-31 T 23-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 Pfam PF06827 Zinc finger found in FPG and IleRS 283 309 1.0E-5 T 23-04-2016 IPR010663 Zinc finger, FPG/IleRS-type DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 169 256 3.5E-22 T 23-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 PANTHER PTHR22993 94 313 8.1E-114 T 23-04-2016 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 PANTHER PTHR22993 2 71 8.1E-114 T 23-04-2016 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 PANTHER PTHR22993:SF15 94 313 8.1E-114 T 23-04-2016 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 PANTHER PTHR22993:SF15 2 71 8.1E-114 T 23-04-2016 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 SMART SM00898 2 150 2.1E-42 T 23-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 SUPERFAMILY SSF46946 169 258 7.65E-27 T 23-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 DC74_RS28015 b5661b2c6730c7013daaf400315ea297 315 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 309 3.0E-82 T 23-04-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 DC74_RS03785 b3ccf488bba013752b48d8ffa4031b6d 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 59 4.8E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03785 b3ccf488bba013752b48d8ffa4031b6d 197 Gene3D G3DSA:1.10.357.10 6 194 2.4E-22 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS03785 b3ccf488bba013752b48d8ffa4031b6d 197 SUPERFAMILY SSF46689 7 73 1.08E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 277 1.6E-72 T 23-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 Hamap MF_00050 Elongation factor Ts [tsf]. 1 278 63.125 T 23-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 SUPERFAMILY SSF54713 57 147 1.57E-17 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 Gene3D G3DSA:1.10.286.20 198 241 1.5E-18 T 23-04-2016 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 23-04-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 Gene3D G3DSA:3.30.479.20 242 277 1.2E-22 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 Gene3D G3DSA:3.30.479.20 152 193 1.2E-22 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 23-04-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 Pfam PF00889 Elongation factor TS 73 277 1.4E-60 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 Gene3D G3DSA:3.30.479.20 57 149 1.3E-19 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 Gene3D G3DSA:1.10.8.10 3 55 9.4E-25 T 23-04-2016 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 SUPERFAMILY SSF54713 150 277 7.72E-38 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 SUPERFAMILY SSF46934 3 55 3.12E-16 T 23-04-2016 IPR009060 UBA-like GO:0005515 DC74_RS28195 fdf431289e0716cc193f2127ea969ecd 278 PANTHER PTHR11741 1 277 7.4E-99 T 23-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 DC74_RS31630 4a503e8546acaf7a59ca1e1ccf58ecf0 437 Gene3D G3DSA:3.90.1150.10 312 428 5.5E-36 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS31630 4a503e8546acaf7a59ca1e1ccf58ecf0 437 Gene3D G3DSA:3.40.640.10 63 311 8.7E-67 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS31630 4a503e8546acaf7a59ca1e1ccf58ecf0 437 Pfam PF00202 Aminotransferase class-III 28 427 3.7E-83 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS31630 4a503e8546acaf7a59ca1e1ccf58ecf0 437 SUPERFAMILY SSF53383 5 427 7.93E-103 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS31630 4a503e8546acaf7a59ca1e1ccf58ecf0 437 PANTHER PTHR11986 8 435 1.8E-198 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS31630 4a503e8546acaf7a59ca1e1ccf58ecf0 437 PANTHER PTHR11986:SF75 8 435 1.8E-198 T 23-04-2016 DC74_RS31725 a0946e37b45c1e0b2cf328a4979c481d 211 SUPERFAMILY SSF51735 1 210 2.31E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31725 a0946e37b45c1e0b2cf328a4979c481d 211 Gene3D G3DSA:3.40.50.720 1 210 1.2E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31725 a0946e37b45c1e0b2cf328a4979c481d 211 Pfam PF13460 NAD(P)H-binding 7 197 2.6E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS31725 a0946e37b45c1e0b2cf328a4979c481d 211 PANTHER PTHR15020 1 209 1.5E-46 T 23-04-2016 DC74_RS09275 73734fc98de34c103728fdefd582204e 151 SUPERFAMILY SSF48619 31 150 4.81E-38 T 23-04-2016 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 DC74_RS09275 73734fc98de34c103728fdefd582204e 151 PANTHER PTHR40787:SF1 1 147 1.7E-85 T 23-04-2016 DC74_RS09275 73734fc98de34c103728fdefd582204e 151 Gene3D G3DSA:1.20.90.10 32 150 2.0E-39 T 23-04-2016 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 DC74_RS09275 73734fc98de34c103728fdefd582204e 151 PANTHER PTHR40787 1 147 1.7E-85 T 23-04-2016 DC74_RS09275 73734fc98de34c103728fdefd582204e 151 Pfam PF09056 Prokaryotic phospholipase A2 47 150 4.3E-34 T 23-04-2016 IPR015141 Phospholipase A2, prokaryotic/fungal DC74_RS08800 9ed176c3ebadee9f5689550a6b8b94c0 195 Pfam PF16157 Domain of unknown function (DUF4865) 1 182 3.8E-67 T 23-04-2016 IPR032349 Protein of unknown function DUF4865 DC74_RS13445 33089382147e1496866807fca80317d1 450 ProSitePatterns PS00216 Sugar transport proteins signature 1. 103 119 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS13445 33089382147e1496866807fca80317d1 450 Pfam PF07690 Major Facilitator Superfamily 61 399 1.5E-40 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS13445 33089382147e1496866807fca80317d1 450 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 48 433 4.1E-102 T 23-04-2016 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 DC74_RS13445 33089382147e1496866807fca80317d1 450 Gene3D G3DSA:1.20.1250.20 47 233 1.3E-30 T 23-04-2016 DC74_RS13445 33089382147e1496866807fca80317d1 450 Gene3D G3DSA:1.20.1250.20 248 446 9.9E-12 T 23-04-2016 DC74_RS13445 33089382147e1496866807fca80317d1 450 PANTHER PTHR23502:SF19 39 427 6.8E-143 T 23-04-2016 DC74_RS13445 33089382147e1496866807fca80317d1 450 PANTHER PTHR23502 39 427 6.8E-143 T 23-04-2016 DC74_RS13445 33089382147e1496866807fca80317d1 450 SUPERFAMILY SSF103473 35 440 2.62E-67 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS15785 b984561691e8538a4476d63278b44126 382 PANTHER PTHR22604:SF139 50 382 5.4E-151 T 23-04-2016 DC74_RS15785 b984561691e8538a4476d63278b44126 382 Gene3D G3DSA:3.40.50.720 4 157 4.8E-23 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15785 b984561691e8538a4476d63278b44126 382 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 136 2.0E-7 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 DC74_RS15785 b984561691e8538a4476d63278b44126 382 Gene3D G3DSA:3.30.360.10 158 373 1.0E-36 T 23-04-2016 DC74_RS15785 b984561691e8538a4476d63278b44126 382 SUPERFAMILY SSF51735 4 172 9.85E-27 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15785 b984561691e8538a4476d63278b44126 382 PANTHER PTHR22604 50 382 5.4E-151 T 23-04-2016 DC74_RS15785 b984561691e8538a4476d63278b44126 382 SUPERFAMILY SSF55347 145 337 3.43E-30 T 23-04-2016 DC74_RS15710 32389f5db16d3cce7a06dd101e7bacc3 330 PANTHER PTHR10584 3 328 4.4E-152 T 23-04-2016 DC74_RS15710 32389f5db16d3cce7a06dd101e7bacc3 330 Gene3D G3DSA:3.40.1190.20 1 328 1.5E-103 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS15710 32389f5db16d3cce7a06dd101e7bacc3 330 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 5 327 6.3E-114 T 23-04-2016 IPR030830 5-dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92|UniPathway: UPA00076 DC74_RS15710 32389f5db16d3cce7a06dd101e7bacc3 330 Pfam PF00294 pfkB family carbohydrate kinase 10 319 8.8E-49 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS15710 32389f5db16d3cce7a06dd101e7bacc3 330 PANTHER PTHR10584:SF194 3 328 4.4E-152 T 23-04-2016 DC74_RS15710 32389f5db16d3cce7a06dd101e7bacc3 330 SUPERFAMILY SSF53613 4 327 1.09E-74 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS11225 a24a7d612470da4aa9e6c7e6af3a73d3 168 Pfam PF14279 HNH endonuclease 84 134 8.4E-11 T 23-04-2016 IPR029471 HNH endonuclease 5 DC74_RS11225 a24a7d612470da4aa9e6c7e6af3a73d3 168 SMART SM00507 71 120 2.2E-12 T 23-04-2016 IPR003615 HNH nuclease DC74_RS11225 a24a7d612470da4aa9e6c7e6af3a73d3 168 PANTHER PTHR33877 1 148 4.4E-60 T 23-04-2016 DC74_RS25815 71a8d4cc5a6498822008d1139c757bdf 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 1.0E-37 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS25815 71a8d4cc5a6498822008d1139c757bdf 307 Gene3D G3DSA:1.10.3720.10 90 302 5.0E-18 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS25815 71a8d4cc5a6498822008d1139c757bdf 307 PANTHER PTHR30465:SF0 1 306 3.0E-112 T 23-04-2016 DC74_RS25815 71a8d4cc5a6498822008d1139c757bdf 307 SUPERFAMILY SSF161098 90 288 1.23E-19 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS25815 71a8d4cc5a6498822008d1139c757bdf 307 PANTHER PTHR30465 1 306 3.0E-112 T 23-04-2016 DC74_RS12785 83316b2b0f2239d21f2adf5be352714b 258 PANTHER PTHR12905 102 254 4.2E-30 T 23-04-2016 DC74_RS12785 83316b2b0f2239d21f2adf5be352714b 258 PANTHER PTHR12905 1 82 4.2E-30 T 23-04-2016 DC74_RS12785 83316b2b0f2239d21f2adf5be352714b 258 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 246 9.6E-10 T 23-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type DC74_RS12785 83316b2b0f2239d21f2adf5be352714b 258 Gene3D G3DSA:3.60.21.10 1 258 3.7E-19 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS12785 83316b2b0f2239d21f2adf5be352714b 258 SUPERFAMILY SSF56300 1 46 1.76E-33 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS12785 83316b2b0f2239d21f2adf5be352714b 258 SUPERFAMILY SSF56300 88 256 1.76E-33 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS12785 83316b2b0f2239d21f2adf5be352714b 258 PANTHER PTHR12905:SF0 102 254 4.2E-30 T 23-04-2016 DC74_RS12785 83316b2b0f2239d21f2adf5be352714b 258 PANTHER PTHR12905:SF0 1 82 4.2E-30 T 23-04-2016 DC74_RS35180 ebdc2cc4de5ca8fd0c4d2abaa0852a35 208 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 4.2E-13 T 23-04-2016 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal DC74_RS35180 ebdc2cc4de5ca8fd0c4d2abaa0852a35 208 Gene3D G3DSA:3.30.230.30 5 131 5.2E-45 T 23-04-2016 IPR001498 Impact, N-terminal DC74_RS35180 ebdc2cc4de5ca8fd0c4d2abaa0852a35 208 Gene3D G3DSA:3.30.70.240 138 207 1.4E-13 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain DC74_RS35180 ebdc2cc4de5ca8fd0c4d2abaa0852a35 208 PANTHER PTHR16301:SF0 1 199 8.1E-57 T 23-04-2016 DC74_RS35180 ebdc2cc4de5ca8fd0c4d2abaa0852a35 208 SUPERFAMILY SSF54211 2 130 6.07E-41 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS35180 ebdc2cc4de5ca8fd0c4d2abaa0852a35 208 PANTHER PTHR16301 1 199 8.1E-57 T 23-04-2016 IPR023582 Impact family DC74_RS35180 ebdc2cc4de5ca8fd0c4d2abaa0852a35 208 SUPERFAMILY SSF54980 137 199 1.1E-15 T 23-04-2016 IPR009022 Elongation factor G, III-V domain DC74_RS35180 ebdc2cc4de5ca8fd0c4d2abaa0852a35 208 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 23-04-2016 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site DC74_RS35180 ebdc2cc4de5ca8fd0c4d2abaa0852a35 208 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 200 3.7E-57 T 23-04-2016 IPR015796 Impact family, bacterial/archaeal DC74_RS35180 ebdc2cc4de5ca8fd0c4d2abaa0852a35 208 Pfam PF01205 Uncharacterized protein family UPF0029 20 124 5.3E-29 T 23-04-2016 IPR001498 Impact, N-terminal DC74_RS31380 a94fe6a600d787f3baf1657f7c01126e 441 Gene3D G3DSA:3.40.630.10 2 177 1.5E-44 T 23-04-2016 DC74_RS31380 a94fe6a600d787f3baf1657f7c01126e 441 Gene3D G3DSA:3.40.630.10 343 431 1.5E-44 T 23-04-2016 DC74_RS31380 a94fe6a600d787f3baf1657f7c01126e 441 SUPERFAMILY SSF53187 2 183 5.99E-45 T 23-04-2016 DC74_RS31380 a94fe6a600d787f3baf1657f7c01126e 441 SUPERFAMILY SSF53187 344 431 5.99E-45 T 23-04-2016 DC74_RS31380 a94fe6a600d787f3baf1657f7c01126e 441 Gene3D G3DSA:3.30.70.360 183 339 3.4E-31 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS31380 a94fe6a600d787f3baf1657f7c01126e 441 PANTHER PTHR11014 2 435 5.2E-82 T 23-04-2016 DC74_RS31380 a94fe6a600d787f3baf1657f7c01126e 441 PANTHER PTHR11014:SF15 2 435 5.2E-82 T 23-04-2016 DC74_RS31380 a94fe6a600d787f3baf1657f7c01126e 441 Pfam PF07687 Peptidase dimerisation domain 181 326 4.1E-12 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS31380 a94fe6a600d787f3baf1657f7c01126e 441 Pfam PF01546 Peptidase family M20/M25/M40 73 417 1.0E-24 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS05555 97b2dc57776b9ced4fbbf568605264a6 139 SUPERFAMILY SSF50331 51 135 9.14E-18 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal DC74_RS05555 97b2dc57776b9ced4fbbf568605264a6 139 Gene3D G3DSA:2.40.50.100 1 67 5.6E-24 T 23-04-2016 DC74_RS05555 97b2dc57776b9ced4fbbf568605264a6 139 Gene3D G3DSA:2.40.50.100 74 137 1.4E-20 T 23-04-2016 DC74_RS05555 97b2dc57776b9ced4fbbf568605264a6 139 Pfam PF03459 TOBE domain 75 134 3.2E-16 T 23-04-2016 IPR005116 Transport-associated OB, type 1 DC74_RS05555 97b2dc57776b9ced4fbbf568605264a6 139 Pfam PF03459 TOBE domain 4 65 4.2E-18 T 23-04-2016 IPR005116 Transport-associated OB, type 1 DC74_RS05555 97b2dc57776b9ced4fbbf568605264a6 139 SUPERFAMILY SSF50331 1 69 2.24E-19 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal DC74_RS05555 97b2dc57776b9ced4fbbf568605264a6 139 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 68 3.8E-21 T 23-04-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 DC74_RS05555 97b2dc57776b9ced4fbbf568605264a6 139 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 74 138 1.9E-17 T 23-04-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 PANTHER PTHR26402 2 209 5.9E-80 T 23-04-2016 DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 SMART SM00421 152 209 4.0E-22 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 Gene3D G3DSA:3.40.50.2300 2 155 1.1E-38 T 23-04-2016 DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 1.1E-18 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 5.6E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 5.6E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 5.6E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 SMART SM00448 2 115 1.8E-30 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-28 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 SUPERFAMILY SSF46894 137 212 1.02E-20 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 SUPERFAMILY SSF52172 2 134 9.82E-33 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 PANTHER PTHR26402:SF564 2 209 5.9E-80 T 23-04-2016 DC74_RS04210 24f62517255c87fc20fb40626e2f6661 225 Gene3D G3DSA:1.10.10.10 156 210 9.1E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32050 94d023de36dd79c0a4b7cd8368b88352 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 2.1E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32050 94d023de36dd79c0a4b7cd8368b88352 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.1E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32050 94d023de36dd79c0a4b7cd8368b88352 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.1E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32050 94d023de36dd79c0a4b7cd8368b88352 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 2.1E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32050 94d023de36dd79c0a4b7cd8368b88352 149 Pfam PF12802 MarR family 40 97 1.1E-10 T 23-04-2016 DC74_RS32050 94d023de36dd79c0a4b7cd8368b88352 149 PANTHER PTHR33164 19 146 3.1E-19 T 23-04-2016 DC74_RS32050 94d023de36dd79c0a4b7cd8368b88352 149 SMART SM00347 34 134 4.8E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32050 94d023de36dd79c0a4b7cd8368b88352 149 Gene3D G3DSA:1.10.10.10 16 145 1.9E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32050 94d023de36dd79c0a4b7cd8368b88352 149 SUPERFAMILY SSF46785 15 145 3.46E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 SUPERFAMILY SSF53850 59 423 2.17E-57 T 23-04-2016 DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 Gene3D G3DSA:3.90.76.10 97 191 2.6E-13 T 23-04-2016 DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 PANTHER PTHR30290 9 283 4.2E-138 T 23-04-2016 DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 PANTHER PTHR30290 310 424 4.2E-138 T 23-04-2016 DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 PANTHER PTHR30290 613 786 4.2E-138 T 23-04-2016 DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 SUPERFAMILY SSF53850 606 785 8.51E-23 T 23-04-2016 DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 122 420 7.6E-43 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 Gene3D G3DSA:3.10.105.10 347 414 8.6E-60 T 23-04-2016 DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 Gene3D G3DSA:3.10.105.10 613 757 8.6E-60 T 23-04-2016 DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 Gene3D G3DSA:3.40.190.10 192 346 4.9E-21 T 23-04-2016 DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 PANTHER PTHR30290:SF29 9 283 4.2E-138 T 23-04-2016 DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 PANTHER PTHR30290:SF29 310 424 4.2E-138 T 23-04-2016 DC74_RS25800 29868e884e3b9061efeef5624f9b241e 786 PANTHER PTHR30290:SF29 613 786 4.2E-138 T 23-04-2016 DC74_RS13910 8f119d29d444ddf2e6a6cea79d3211e3 821 Pfam PF15608 PELOTA RNA binding domain 725 804 1.5E-34 T 23-04-2016 IPR028157 PELOTA RNA-binding domain KEGG: 00900+3.4.22.- DC74_RS13910 8f119d29d444ddf2e6a6cea79d3211e3 821 SUPERFAMILY SSF53271 89 199 1.56E-6 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS13910 8f119d29d444ddf2e6a6cea79d3211e3 821 Pfam PF15609 Phosphoribosyl transferase 39 226 1.4E-70 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS13910 8f119d29d444ddf2e6a6cea79d3211e3 821 Pfam PF12500 TRSP domain C terminus to PRTase_2 275 420 6.1E-45 T 23-04-2016 IPR022537 TRSP domain DC74_RS13910 8f119d29d444ddf2e6a6cea79d3211e3 821 Pfam PF11202 Phosphoribosyl transferase (PRTase) 451 698 2.4E-104 T 23-04-2016 IPR011215 Phosphoribosyl transferase KEGG: 00900+3.4.22.- DC74_RS13910 8f119d29d444ddf2e6a6cea79d3211e3 821 Gene3D G3DSA:3.40.50.2020 82 198 5.2E-6 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS19020 29080046b8076096a122365291e12360 627 PANTHER PTHR22773 1 576 1.2E-243 T 23-04-2016 DC74_RS19020 29080046b8076096a122365291e12360 627 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 6.0E-60 T 23-04-2016 DC74_RS19020 29080046b8076096a122365291e12360 627 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 6.0E-60 T 23-04-2016 DC74_RS19020 29080046b8076096a122365291e12360 627 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 6.0E-60 T 23-04-2016 DC74_RS19020 29080046b8076096a122365291e12360 627 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 6.0E-60 T 23-04-2016 DC74_RS19020 29080046b8076096a122365291e12360 627 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 6.0E-60 T 23-04-2016 DC74_RS19020 29080046b8076096a122365291e12360 627 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 246 272 6.0E-60 T 23-04-2016 DC74_RS19020 29080046b8076096a122365291e12360 627 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 6.0E-60 T 23-04-2016 DC74_RS19020 29080046b8076096a122365291e12360 627 Pfam PF00361 Proton-conducting membrane transporter 135 422 6.9E-83 T 23-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 DC74_RS19020 29080046b8076096a122365291e12360 627 PANTHER PTHR22773:SF50 1 576 1.2E-243 T 23-04-2016 DC74_RS19020 29080046b8076096a122365291e12360 627 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 123 9.2E-25 T 23-04-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal DC74_RS19020 29080046b8076096a122365291e12360 627 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 3 621 1.0E-236 T 23-04-2016 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 DC74_RS19020 29080046b8076096a122365291e12360 627 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 420 442 7.2E-11 T 23-04-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 DC74_RS19020 29080046b8076096a122365291e12360 627 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 7.2E-11 T 23-04-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 DC74_RS19020 29080046b8076096a122365291e12360 627 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 60 84 7.2E-11 T 23-04-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 DC74_RS19020 29080046b8076096a122365291e12360 627 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 264 286 7.2E-11 T 23-04-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 DC74_RS08520 beb23637105066f0c9fef66a86cd5069 315 SUPERFAMILY SSF53850 101 291 6.83E-24 T 23-04-2016 DC74_RS08520 beb23637105066f0c9fef66a86cd5069 315 PANTHER PTHR30346 1 313 1.3E-92 T 23-04-2016 DC74_RS08520 beb23637105066f0c9fef66a86cd5069 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS08520 beb23637105066f0c9fef66a86cd5069 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS08520 beb23637105066f0c9fef66a86cd5069 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS08520 beb23637105066f0c9fef66a86cd5069 315 SUPERFAMILY SSF46785 2 83 2.5E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08520 beb23637105066f0c9fef66a86cd5069 315 Gene3D G3DSA:3.40.190.10 174 265 7.7E-5 T 23-04-2016 DC74_RS08520 beb23637105066f0c9fef66a86cd5069 315 Pfam PF03466 LysR substrate binding domain 101 291 3.9E-19 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS08520 beb23637105066f0c9fef66a86cd5069 315 Gene3D G3DSA:3.40.190.10 102 173 1.8E-11 T 23-04-2016 DC74_RS08520 beb23637105066f0c9fef66a86cd5069 315 Gene3D G3DSA:1.10.10.10 2 83 8.7E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08520 beb23637105066f0c9fef66a86cd5069 315 PANTHER PTHR30346:SF7 1 313 1.3E-92 T 23-04-2016 DC74_RS08520 beb23637105066f0c9fef66a86cd5069 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.2E-19 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS01405 c38d1e03f4cba0f7a4307f8147b1cd46 379 Gene3D G3DSA:1.20.1250.20 194 366 8.2E-15 T 23-04-2016 DC74_RS01405 c38d1e03f4cba0f7a4307f8147b1cd46 379 SUPERFAMILY SSF103473 2 367 7.46E-45 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS01405 c38d1e03f4cba0f7a4307f8147b1cd46 379 Gene3D G3DSA:1.20.1250.20 4 184 1.3E-21 T 23-04-2016 DC74_RS01405 c38d1e03f4cba0f7a4307f8147b1cd46 379 PANTHER PTHR23501 4 366 1.0E-68 T 23-04-2016 DC74_RS01405 c38d1e03f4cba0f7a4307f8147b1cd46 379 PANTHER PTHR23501:SF4 4 366 1.0E-68 T 23-04-2016 DC74_RS01405 c38d1e03f4cba0f7a4307f8147b1cd46 379 Pfam PF07690 Major Facilitator Superfamily 6 183 7.4E-21 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS01405 c38d1e03f4cba0f7a4307f8147b1cd46 379 Pfam PF07690 Major Facilitator Superfamily 203 368 2.6E-12 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS36465 7b11e27f90d00553a94959184a997963 282 Pfam PF00561 alpha/beta hydrolase fold 35 145 2.2E-7 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36465 7b11e27f90d00553a94959184a997963 282 SUPERFAMILY SSF53474 32 281 1.43E-22 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS36465 7b11e27f90d00553a94959184a997963 282 Gene3D G3DSA:3.40.50.1820 29 281 2.9E-21 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS10310 ed1c8198762c8802b3472dca10734cd3 271 Gene3D G3DSA:3.60.20.10 3 242 3.7E-86 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS10310 ed1c8198762c8802b3472dca10734cd3 271 SUPERFAMILY SSF56235 10 231 1.82E-43 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS10310 ed1c8198762c8802b3472dca10734cd3 271 Pfam PF00227 Proteasome subunit 25 207 2.6E-28 T 23-04-2016 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: REACT_11045|Reactome: REACT_13|Reactome: REACT_13635|Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_383|Reactome: REACT_578|Reactome: REACT_6185|Reactome: REACT_6850 DC74_RS10310 ed1c8198762c8802b3472dca10734cd3 271 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 234 49.73 T 23-04-2016 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 UniPathway: UPA00997 DC74_RS10310 ed1c8198762c8802b3472dca10734cd3 271 PANTHER PTHR11599:SF38 24 237 1.1E-57 T 23-04-2016 DC74_RS10310 ed1c8198762c8802b3472dca10734cd3 271 PANTHER PTHR11599 24 237 1.1E-57 T 23-04-2016 DC74_RS10310 ed1c8198762c8802b3472dca10734cd3 271 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 230 2.8E-117 T 23-04-2016 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 UniPathway: UPA00997 DC74_RS03180 8b797d2116af1133c78be7e3138ed193 275 PANTHER PTHR30007 7 274 7.3E-67 T 23-04-2016 DC74_RS03180 8b797d2116af1133c78be7e3138ed193 275 PANTHER PTHR30007:SF0 7 274 7.3E-67 T 23-04-2016 DC74_RS03180 8b797d2116af1133c78be7e3138ed193 275 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 89 2.2E-21 T 23-04-2016 IPR025161 Putative transposase IS4/IS5 family DC74_RS03180 8b797d2116af1133c78be7e3138ed193 275 Pfam PF01609 Transposase DDE domain 106 192 2.7E-9 T 23-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 DC74_RS28615 9d5e4da7c517b29c90a1d8817fe3fe98 561 SMART SM00849 31 225 5.1E-24 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS28615 9d5e4da7c517b29c90a1d8817fe3fe98 561 Pfam PF00753 Metallo-beta-lactamase superfamily 28 174 4.4E-14 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS28615 9d5e4da7c517b29c90a1d8817fe3fe98 561 PIRSF PIRSF004803 12 561 5.8E-207 T 23-04-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 DC74_RS28615 9d5e4da7c517b29c90a1d8817fe3fe98 561 Hamap MF_01491 Ribonuclease J [rnj]. 14 561 41.067 T 23-04-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 DC74_RS28615 9d5e4da7c517b29c90a1d8817fe3fe98 561 PANTHER PTHR11203:SF22 10 561 1.7E-222 T 23-04-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 DC74_RS28615 9d5e4da7c517b29c90a1d8817fe3fe98 561 Gene3D G3DSA:3.60.15.10 18 265 3.5E-78 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS28615 9d5e4da7c517b29c90a1d8817fe3fe98 561 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 411 5.8E-10 T 23-04-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain DC74_RS28615 9d5e4da7c517b29c90a1d8817fe3fe98 561 SUPERFAMILY SSF56281 19 432 4.44E-98 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS28615 9d5e4da7c517b29c90a1d8817fe3fe98 561 PANTHER PTHR11203 10 561 1.7E-222 T 23-04-2016 DC74_RS28615 9d5e4da7c517b29c90a1d8817fe3fe98 561 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 20 558 7.6E-152 T 23-04-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 DC74_RS39545 5b5ab3c2a7d9e41d49fc68268c1d6012 237 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS39545 5b5ab3c2a7d9e41d49fc68268c1d6012 237 PANTHER PTHR24220 9 212 2.3E-81 T 23-04-2016 DC74_RS39545 5b5ab3c2a7d9e41d49fc68268c1d6012 237 SMART SM00382 21 206 2.6E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS39545 5b5ab3c2a7d9e41d49fc68268c1d6012 237 SUPERFAMILY SSF52540 8 208 1.54E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39545 5b5ab3c2a7d9e41d49fc68268c1d6012 237 Pfam PF00005 ABC transporter 12 158 1.6E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS39545 5b5ab3c2a7d9e41d49fc68268c1d6012 237 Gene3D G3DSA:3.40.50.300 7 209 1.6E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS08215 cd7686d418a51ae7d7ac679c251d9072 433 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 26 375 5.6E-28 T 23-04-2016 IPR010645 Uncharacterised MFS-type transporter YbfB DC74_RS08215 cd7686d418a51ae7d7ac679c251d9072 433 PANTHER PTHR23501 14 424 3.9E-20 T 23-04-2016 DC74_RS08215 cd7686d418a51ae7d7ac679c251d9072 433 SUPERFAMILY SSF103473 8 396 3.79E-48 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS08215 cd7686d418a51ae7d7ac679c251d9072 433 Gene3D G3DSA:1.20.1250.20 18 199 4.7E-25 T 23-04-2016 DC74_RS08215 cd7686d418a51ae7d7ac679c251d9072 433 Gene3D G3DSA:1.20.1250.20 207 391 2.2E-13 T 23-04-2016 DC74_RS09535 f0bfd62160ef8b9c7698bea141b09b87 138 Pfam PF06103 Bacterial protein of unknown function (DUF948) 1 81 9.7E-12 T 23-04-2016 IPR009293 Uncharacterised protein family UPF0478 DC74_RS35945 4ac5fba3b13192f325438fb2dc535d2e 467 PANTHER PTHR23501 20 457 9.9E-120 T 23-04-2016 DC74_RS35945 4ac5fba3b13192f325438fb2dc535d2e 467 SUPERFAMILY SSF103473 257 456 1.31E-67 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS35945 4ac5fba3b13192f325438fb2dc535d2e 467 SUPERFAMILY SSF103473 14 205 1.31E-67 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS35945 4ac5fba3b13192f325438fb2dc535d2e 467 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 426 2.1E-71 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS35945 4ac5fba3b13192f325438fb2dc535d2e 467 Gene3D G3DSA:1.20.1250.20 272 451 3.3E-21 T 23-04-2016 DC74_RS35945 4ac5fba3b13192f325438fb2dc535d2e 467 Gene3D G3DSA:1.20.1250.20 22 199 4.0E-27 T 23-04-2016 DC74_RS35945 4ac5fba3b13192f325438fb2dc535d2e 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 24 48 2.8E-7 T 23-04-2016 DC74_RS35945 4ac5fba3b13192f325438fb2dc535d2e 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 2.8E-7 T 23-04-2016 DC74_RS35945 4ac5fba3b13192f325438fb2dc535d2e 467 Pfam PF07690 Major Facilitator Superfamily 25 418 1.4E-58 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS35945 4ac5fba3b13192f325438fb2dc535d2e 467 PANTHER PTHR23501:SF7 20 457 9.9E-120 T 23-04-2016 DC74_RS07295 ed87a93de333d280e172ee9d807452f2 200 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 86 106 - T 23-04-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS07295 ed87a93de333d280e172ee9d807452f2 200 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 41 48 - T 23-04-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS07295 ed87a93de333d280e172ee9d807452f2 200 Gene3D G3DSA:3.40.1050.10 17 194 4.1E-53 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS07295 ed87a93de333d280e172ee9d807452f2 200 PANTHER PTHR11002 19 200 4.0E-49 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS07295 ed87a93de333d280e172ee9d807452f2 200 Pfam PF00484 Carbonic anhydrase 36 187 3.5E-41 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS07295 ed87a93de333d280e172ee9d807452f2 200 SMART SM00947 29 191 1.0E-54 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS07295 ed87a93de333d280e172ee9d807452f2 200 SUPERFAMILY SSF53056 19 198 7.98E-50 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DC74_RS33410 4e6b71a69a919b3afe768220a114d95f 184 PANTHER PTHR34796 24 161 6.6E-30 T 23-04-2016 DC74_RS33410 4e6b71a69a919b3afe768220a114d95f 184 Pfam PF03745 Domain of unknown function (DUF309) 67 123 7.0E-20 T 23-04-2016 IPR005500 Protein of unknown function DUF309 DC74_RS33410 4e6b71a69a919b3afe768220a114d95f 184 SUPERFAMILY SSF140663 48 161 2.49E-29 T 23-04-2016 IPR023203 TTHA0068-like domain DC74_RS33410 4e6b71a69a919b3afe768220a114d95f 184 PANTHER PTHR34796:SF1 24 161 6.6E-30 T 23-04-2016 DC74_RS33410 4e6b71a69a919b3afe768220a114d95f 184 Gene3D G3DSA:1.10.3450.10 36 163 1.8E-26 T 23-04-2016 IPR023203 TTHA0068-like domain DC74_RS25020 d78ab6f205543ec9e1b658de50508bce 476 Gene3D G3DSA:3.40.309.10 270 454 4.7E-63 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS25020 d78ab6f205543ec9e1b658de50508bce 476 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS25020 d78ab6f205543ec9e1b658de50508bce 476 PANTHER PTHR11699 6 476 1.6E-222 T 23-04-2016 DC74_RS25020 d78ab6f205543ec9e1b658de50508bce 476 SUPERFAMILY SSF53720 19 475 1.02E-165 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS25020 d78ab6f205543ec9e1b658de50508bce 476 Pfam PF00171 Aldehyde dehydrogenase family 38 476 7.2E-166 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS25020 d78ab6f205543ec9e1b658de50508bce 476 Gene3D G3DSA:3.40.605.10 20 269 4.2E-100 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS12310 5c4af20d8efe7b37d3bfa65ea9855989 144 Pfam PF10825 Protein of unknown function (DUF2752) 49 97 2.0E-13 T 23-04-2016 IPR021215 Protein of unknown function DUF2752 DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.4E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.4E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.4E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 3.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 3.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 SUPERFAMILY SSF51735 3 234 6.31E-61 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 Gene3D G3DSA:3.40.50.720 1 238 1.7E-67 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 Pfam PF00106 short chain dehydrogenase 5 199 1.1E-37 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 PANTHER PTHR24322 8 130 1.9E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38550 5fdd31faa068be48a35751d546b15b2c 238 PANTHER PTHR24322 158 189 1.9E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS22485 ac3c3f7a0dd0e7d104f9b71375af8cd6 392 Gene3D G3DSA:3.10.580.10 256 370 8.9E-11 T 23-04-2016 DC74_RS22485 ac3c3f7a0dd0e7d104f9b71375af8cd6 392 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 14 369 2.8E-100 T 23-04-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 DC74_RS22485 ac3c3f7a0dd0e7d104f9b71375af8cd6 392 Gene3D G3DSA:3.40.50.300 1 238 1.8E-77 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22485 ac3c3f7a0dd0e7d104f9b71375af8cd6 392 SUPERFAMILY SSF52540 1 239 9.24E-76 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22485 ac3c3f7a0dd0e7d104f9b71375af8cd6 392 SMART SM00382 27 222 7.7E-19 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS22485 ac3c3f7a0dd0e7d104f9b71375af8cd6 392 PANTHER PTHR24220 3 267 2.5E-144 T 23-04-2016 DC74_RS22485 ac3c3f7a0dd0e7d104f9b71375af8cd6 392 SUPERFAMILY SSF54631 251 371 7.72E-12 T 23-04-2016 DC74_RS22485 ac3c3f7a0dd0e7d104f9b71375af8cd6 392 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS22485 ac3c3f7a0dd0e7d104f9b71375af8cd6 392 Pfam PF00005 ABC transporter 19 164 2.3E-33 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS22485 ac3c3f7a0dd0e7d104f9b71375af8cd6 392 PANTHER PTHR24220:SF350 3 267 2.5E-144 T 23-04-2016 DC74_RS17960 d4fc7a1c1efaca0aa4fe35563fe0959e 396 Pfam PF02515 CoA-transferase family III 13 376 1.2E-113 T 23-04-2016 IPR003673 CoA-transferase family III GO:0003824 DC74_RS17960 d4fc7a1c1efaca0aa4fe35563fe0959e 396 PANTHER PTHR24023 85 302 1.4E-15 T 23-04-2016 DC74_RS17960 d4fc7a1c1efaca0aa4fe35563fe0959e 396 PANTHER PTHR24023:SF593 85 302 1.4E-15 T 23-04-2016 DC74_RS17960 d4fc7a1c1efaca0aa4fe35563fe0959e 396 Gene3D G3DSA:3.30.1540.10 230 312 2.9E-29 T 23-04-2016 DC74_RS17960 d4fc7a1c1efaca0aa4fe35563fe0959e 396 SUPERFAMILY SSF89796 11 386 1.31E-113 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS17960 d4fc7a1c1efaca0aa4fe35563fe0959e 396 Gene3D G3DSA:3.40.50.10540 313 382 2.3E-92 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS17960 d4fc7a1c1efaca0aa4fe35563fe0959e 396 Gene3D G3DSA:3.40.50.10540 10 224 2.3E-92 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS29630 271d180300735c70bfce0f28fbc1350c 133 Pfam PF05713 Bacterial mobilisation protein (MobC) 81 119 2.9E-6 T 23-04-2016 IPR008687 Bacterial mobilisation DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 Gene3D G3DSA:3.30.450.20 29 82 1.1E-11 T 23-04-2016 DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 PRINTS PR00344 Bacterial sensor protein C-terminal signature 314 324 2.0E-16 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 310 2.0E-16 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 363 2.0E-16 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 344 2.0E-16 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 PANTHER PTHR24423 29 367 1.6E-77 T 23-04-2016 DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 Gene3D G3DSA:1.10.287.130 137 196 3.2E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 SMART SM00387 256 366 1.9E-37 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 Pfam PF00512 His Kinase A (phospho-acceptor) domain 145 211 2.8E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 257 364 3.3E-24 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 SUPERFAMILY SSF55874 201 365 8.12E-39 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 Pfam PF00989 PAS fold 30 72 3.3E-6 T 23-04-2016 IPR013767 PAS fold GO:0006355 DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 SMART SM00388 143 211 9.1E-18 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 SMART SM00091 22 87 3.9E-4 T 23-04-2016 IPR000014 PAS domain DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 SUPERFAMILY SSF47384 135 212 2.94E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 SUPERFAMILY SSF55785 29 119 3.06E-11 T 23-04-2016 IPR000014 PAS domain DC74_RS10090 969d257f996a8365f8ec92ff93ebe9e8 371 Gene3D G3DSA:3.30.565.10 197 365 3.6E-40 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS37320 81b76e0ca92f7eec53e193c17144d075 190 Pfam PF11706 CGNR zinc finger 146 189 5.7E-17 T 23-04-2016 IPR021005 Zinc finger, CGNR DC74_RS37320 81b76e0ca92f7eec53e193c17144d075 190 SUPERFAMILY SSF160904 7 188 3.01E-38 T 23-04-2016 DC74_RS37320 81b76e0ca92f7eec53e193c17144d075 190 PANTHER PTHR35525 14 190 6.8E-27 T 23-04-2016 DC74_RS37320 81b76e0ca92f7eec53e193c17144d075 190 Pfam PF07336 Putative stress-induced transcription regulator 14 133 7.0E-14 T 23-04-2016 IPR010852 Putative stress-induced transcription regulator DC74_RS37320 81b76e0ca92f7eec53e193c17144d075 190 Gene3D G3DSA:1.10.3300.10 9 190 1.3E-41 T 23-04-2016 IPR023286 ABATE domain DC74_RS33840 0d65d7bacb143618b3314f45e49d54cb 341 SUPERFAMILY SSF51735 121 309 1.41E-51 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS33840 0d65d7bacb143618b3314f45e49d54cb 341 Gene3D G3DSA:3.40.50.720 130 309 2.8E-58 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS33840 0d65d7bacb143618b3314f45e49d54cb 341 PANTHER PTHR10996 50 341 1.8E-88 T 23-04-2016 DC74_RS33840 0d65d7bacb143618b3314f45e49d54cb 341 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 53 340 6.6E-16 T 23-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 DC74_RS33840 0d65d7bacb143618b3314f45e49d54cb 341 Gene3D G3DSA:3.40.50.720 52 129 1.2E-21 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS33840 0d65d7bacb143618b3314f45e49d54cb 341 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 131 308 2.5E-54 T 23-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DC74_RS33840 0d65d7bacb143618b3314f45e49d54cb 341 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 247 263 - T 23-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site DC74_RS33840 0d65d7bacb143618b3314f45e49d54cb 341 SUPERFAMILY SSF52283 51 156 2.84E-21 T 23-04-2016 DC74_RS37220 c96130733dc2b880208097a390627cf8 271 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 6 266 2.4E-57 T 23-04-2016 IPR002747 SAM-dependent chlorinase/fluorinase DC74_RS37220 c96130733dc2b880208097a390627cf8 271 PIRSF PIRSF006779 2 271 1.5E-57 T 23-04-2016 IPR002747 SAM-dependent chlorinase/fluorinase DC74_RS37220 c96130733dc2b880208097a390627cf8 271 SUPERFAMILY SSF102522 4 164 4.05E-41 T 23-04-2016 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal DC74_RS37220 c96130733dc2b880208097a390627cf8 271 SUPERFAMILY SSF101852 169 268 9.55E-25 T 23-04-2016 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal DC74_RS37220 c96130733dc2b880208097a390627cf8 271 Gene3D G3DSA:2.40.30.90 167 268 7.2E-25 T 23-04-2016 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal DC74_RS37220 c96130733dc2b880208097a390627cf8 271 PANTHER PTHR35092 2 268 2.7E-60 T 23-04-2016 DC74_RS15990 c7bf8595afe847733be11f4d7c0c64db 286 PANTHER PTHR12176:SF22 23 254 2.9E-116 T 23-04-2016 DC74_RS15990 c7bf8595afe847733be11f4d7c0c64db 286 Pfam PF01564 Spermine/spermidine synthase 56 182 1.1E-5 T 23-04-2016 DC74_RS15990 c7bf8595afe847733be11f4d7c0c64db 286 PANTHER PTHR12176 23 254 2.9E-116 T 23-04-2016 DC74_RS15990 c7bf8595afe847733be11f4d7c0c64db 286 Gene3D G3DSA:3.40.50.150 27 274 1.8E-65 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS15990 c7bf8595afe847733be11f4d7c0c64db 286 SUPERFAMILY SSF53335 24 243 4.14E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS35185 74753622d4fe6dc437d8dd50acfe6f78 490 PIRSF PIRSF006060 3 485 1.1E-78 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS35185 74753622d4fe6dc437d8dd50acfe6f78 490 Pfam PF13520 Amino acid permease 15 417 4.7E-49 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS35185 74753622d4fe6dc437d8dd50acfe6f78 490 PANTHER PTHR11785 5 472 1.9E-61 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS34205 ada21649c4f44e8ff6ec5644c59649d7 252 SUPERFAMILY SSF46689 3 67 1.05E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS34205 ada21649c4f44e8ff6ec5644c59649d7 252 PANTHER PTHR30055 3 235 7.5E-19 T 23-04-2016 DC74_RS34205 ada21649c4f44e8ff6ec5644c59649d7 252 Gene3D G3DSA:1.10.357.10 3 193 6.2E-26 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS34205 ada21649c4f44e8ff6ec5644c59649d7 252 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.1E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34205 ada21649c4f44e8ff6ec5644c59649d7 252 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.1E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34205 ada21649c4f44e8ff6ec5644c59649d7 252 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 53 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS34205 ada21649c4f44e8ff6ec5644c59649d7 252 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 1.9E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS24795 4abbce90177736cd7872bce659b0957a 114 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 1 99 1.8E-26 T 23-04-2016 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 UniPathway: UPA00223 DC74_RS24795 4abbce90177736cd7872bce659b0957a 114 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 1 96 1.7E-21 T 23-04-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 UniPathway: UPA00223 DC74_RS24795 4abbce90177736cd7872bce659b0957a 114 Gene3D G3DSA:1.20.1300.10 1 101 6.4E-28 T 23-04-2016 DC74_RS24795 4abbce90177736cd7872bce659b0957a 114 PANTHER PTHR41910 1 112 2.9E-37 T 23-04-2016 DC74_RS24795 4abbce90177736cd7872bce659b0957a 114 SUPERFAMILY SSF81343 1 101 9.16E-24 T 23-04-2016 DC74_RS24795 4abbce90177736cd7872bce659b0957a 114 PIRSF PIRSF000178 1 104 5.0E-10 T 23-04-2016 DC74_RS35440 abff6f086fb91ab11805751dd6be21d2 98 Gene3D G3DSA:3.30.370.10 8 86 1.1E-11 T 23-04-2016 IPR000468 Barstar (barnase inhibitor) DC74_RS35440 abff6f086fb91ab11805751dd6be21d2 98 SUPERFAMILY SSF52038 8 91 1.7E-16 T 23-04-2016 IPR000468 Barstar (barnase inhibitor) DC74_RS35440 abff6f086fb91ab11805751dd6be21d2 98 Pfam PF01337 Barstar (barnase inhibitor) 10 86 7.9E-10 T 23-04-2016 IPR000468 Barstar (barnase inhibitor) DC74_RS38030 b947524171a488730af30bee5afe44a2 372 Gene3D G3DSA:3.75.10.10 2 365 4.3E-116 T 23-04-2016 DC74_RS38030 b947524171a488730af30bee5afe44a2 372 SUPERFAMILY SSF55909 3 366 3.39E-87 T 23-04-2016 DC74_RS38030 b947524171a488730af30bee5afe44a2 372 PANTHER PTHR10488 3 366 1.4E-103 T 23-04-2016 IPR033195 Glycine/inosamine-phosphate amidinotransferase GO:0015067 DC74_RS07705 7d3559f40c7e1d5dda92c94cd2337807 143 Gene3D G3DSA:1.10.260.40 51 118 2.1E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS07705 7d3559f40c7e1d5dda92c94cd2337807 143 Pfam PF13560 Helix-turn-helix domain 52 108 8.1E-11 T 23-04-2016 DC74_RS07705 7d3559f40c7e1d5dda92c94cd2337807 143 SMART SM00530 54 109 4.7E-10 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS07705 7d3559f40c7e1d5dda92c94cd2337807 143 SUPERFAMILY SSF47413 45 114 2.4E-12 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS17435 c1981d23a6704eb21246facebba1456c 261 PANTHER PTHR24094:SF10 65 243 1.2E-46 T 23-04-2016 DC74_RS17435 c1981d23a6704eb21246facebba1456c 261 Pfam PF07510 Protein of unknown function (DUF1524) 100 236 8.0E-20 T 23-04-2016 IPR011089 Domain of unknown function DUF1524 DC74_RS17435 c1981d23a6704eb21246facebba1456c 261 PANTHER PTHR24094 65 243 1.2E-46 T 23-04-2016 DC74_RS10375 6a4cfe18c3a09638e1618ee0693d1da2 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 23 199 9.7E-26 T 23-04-2016 IPR023214 HAD-like domain DC74_RS10375 6a4cfe18c3a09638e1618ee0693d1da2 237 PANTHER PTHR18901 18 220 8.2E-58 T 23-04-2016 DC74_RS10375 6a4cfe18c3a09638e1618ee0693d1da2 237 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 87 199 1.4E-15 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS10375 6a4cfe18c3a09638e1618ee0693d1da2 237 PANTHER PTHR18901:SF21 18 220 8.2E-58 T 23-04-2016 DC74_RS10375 6a4cfe18c3a09638e1618ee0693d1da2 237 SUPERFAMILY SSF56784 19 202 1.02E-46 T 23-04-2016 IPR023214 HAD-like domain DC74_RS10375 6a4cfe18c3a09638e1618ee0693d1da2 237 Gene3D G3DSA:3.40.50.1000 104 220 1.5E-40 T 23-04-2016 IPR023214 HAD-like domain DC74_RS10375 6a4cfe18c3a09638e1618ee0693d1da2 237 Gene3D G3DSA:3.40.50.1000 15 32 1.5E-40 T 23-04-2016 IPR023214 HAD-like domain DC74_RS29295 a3e1bd5005968f27881d54e420a2d0fc 344 PANTHER PTHR24220:SF0 37 264 2.5E-93 T 23-04-2016 DC74_RS29295 a3e1bd5005968f27881d54e420a2d0fc 344 SMART SM00382 60 246 1.0E-8 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS29295 a3e1bd5005968f27881d54e420a2d0fc 344 Pfam PF00005 ABC transporter 52 194 1.8E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS29295 a3e1bd5005968f27881d54e420a2d0fc 344 SUPERFAMILY SSF52540 36 257 2.13E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29295 a3e1bd5005968f27881d54e420a2d0fc 344 Gene3D G3DSA:3.40.50.300 27 257 3.6E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29295 a3e1bd5005968f27881d54e420a2d0fc 344 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS29295 a3e1bd5005968f27881d54e420a2d0fc 344 PANTHER PTHR24220 37 264 2.5E-93 T 23-04-2016 DC74_RS31340 236ed8b8b12a7fe3e12065a0dde3561f 170 SUPERFAMILY SSF158694 9 163 2.22E-40 T 23-04-2016 DC74_RS31340 236ed8b8b12a7fe3e12065a0dde3561f 170 Gene3D G3DSA:1.10.3330.10 17 164 5.8E-41 T 23-04-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|UniPathway: UPA00394 DC74_RS31340 236ed8b8b12a7fe3e12065a0dde3561f 170 Pfam PF09349 OHCU decarboxylase 13 161 7.8E-35 T 23-04-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|UniPathway: UPA00394 DC74_RS31340 236ed8b8b12a7fe3e12065a0dde3561f 170 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 12 164 6.1E-57 T 23-04-2016 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 PRINTS PR00359 B-class P450 signature 297 308 1.4E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 PRINTS PR00359 B-class P450 signature 215 237 1.4E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 PRINTS PR00359 B-class P450 signature 180 195 1.4E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 PRINTS PR00359 B-class P450 signature 377 388 1.4E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 PRINTS PR00359 B-class P450 signature 114 125 1.4E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 PRINTS PR00359 B-class P450 signature 163 179 1.4E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 PRINTS PR00359 B-class P450 signature 368 377 1.4E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 PRINTS PR00359 B-class P450 signature 315 342 1.4E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 PRINTS PR00359 B-class P450 signature 343 358 1.4E-55 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 370 379 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 PANTHER PTHR24286:SF42 111 429 1.0E-86 T 23-04-2016 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 Gene3D G3DSA:1.10.630.10 19 428 1.6E-122 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 SUPERFAMILY SSF48264 25 428 3.8E-97 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 PANTHER PTHR24286 111 429 1.0E-86 T 23-04-2016 DC74_RS34200 0af22c838574f1012d9a19824a6660b9 429 Pfam PF00067 Cytochrome P450 214 398 3.2E-26 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS32825 aec6584b1c948d69bd0d425155453efc 300 Gene3D G3DSA:3.40.50.150 68 193 2.6E-21 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS32825 aec6584b1c948d69bd0d425155453efc 300 SUPERFAMILY SSF53335 53 267 2.39E-27 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS32825 aec6584b1c948d69bd0d425155453efc 300 Pfam PF13649 Methyltransferase domain 79 174 1.3E-11 T 23-04-2016 DC74_RS32825 aec6584b1c948d69bd0d425155453efc 300 PANTHER PTHR10108:SF868 71 188 1.5E-31 T 23-04-2016 DC74_RS32825 aec6584b1c948d69bd0d425155453efc 300 PANTHER PTHR10108:SF868 215 260 1.5E-31 T 23-04-2016 DC74_RS32825 aec6584b1c948d69bd0d425155453efc 300 PANTHER PTHR10108 71 188 1.5E-31 T 23-04-2016 DC74_RS32825 aec6584b1c948d69bd0d425155453efc 300 PANTHER PTHR10108 215 260 1.5E-31 T 23-04-2016 DC74_RS13545 6c06eefe8db544e5bd675026b997545d 397 SUPERFAMILY SSF53254 194 396 3.67E-53 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS13545 6c06eefe8db544e5bd675026b997545d 397 Pfam PF13456 Reverse transcriptase-like 10 131 9.5E-18 T 23-04-2016 DC74_RS13545 6c06eefe8db544e5bd675026b997545d 397 Gene3D G3DSA:3.30.420.10 3 138 2.6E-21 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS13545 6c06eefe8db544e5bd675026b997545d 397 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 196 392 1.6E-57 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS13545 6c06eefe8db544e5bd675026b997545d 397 PIRSF PIRSF036922 1 397 3.5E-179 T 23-04-2016 IPR014636 RNase H, phosphoglycerate mutase domain-containing DC74_RS13545 6c06eefe8db544e5bd675026b997545d 397 SMART SM00855 195 352 7.5E-17 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS13545 6c06eefe8db544e5bd675026b997545d 397 PANTHER PTHR23029:SF34 135 397 2.7E-118 T 23-04-2016 DC74_RS13545 6c06eefe8db544e5bd675026b997545d 397 PANTHER PTHR23029 135 397 2.7E-118 T 23-04-2016 DC74_RS13545 6c06eefe8db544e5bd675026b997545d 397 Gene3D G3DSA:3.40.50.1240 194 397 1.7E-56 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS13545 6c06eefe8db544e5bd675026b997545d 397 SUPERFAMILY SSF53098 5 130 1.9E-29 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 224 4.7E-27 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 SUPERFAMILY SSF56645 13 249 6.81E-72 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 125 5.0E-22 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 132 144 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 Gene3D G3DSA:2.40.110.10 129 223 1.9E-39 T 23-04-2016 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 Gene3D G3DSA:1.10.540.10 15 125 1.6E-27 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 PIRSF PIRSF016578 6 390 1.2E-14 T 23-04-2016 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 PANTHER PTHR10909 10 386 1.2E-173 T 23-04-2016 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 Gene3D G3DSA:1.20.140.10 224 386 4.0E-71 T 23-04-2016 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 SUPERFAMILY SSF47203 234 386 2.09E-59 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 1.2E-49 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS34785 6ce46d623a111c974bdab97da65ad584 390 PANTHER PTHR10909:SF305 10 386 1.2E-173 T 23-04-2016 DC74_RS36250 ba257f1a57729c18f3d1c67a2d06ba2d 196 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 42 68 1.4E-19 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS36250 ba257f1a57729c18f3d1c67a2d06ba2d 196 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 129 153 1.4E-19 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS36250 ba257f1a57729c18f3d1c67a2d06ba2d 196 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 156 170 1.4E-19 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS36250 ba257f1a57729c18f3d1c67a2d06ba2d 196 SUPERFAMILY SSF55486 37 168 1.35E-22 T 23-04-2016 DC74_RS36250 ba257f1a57729c18f3d1c67a2d06ba2d 196 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 43 164 6.0E-26 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS36250 ba257f1a57729c18f3d1c67a2d06ba2d 196 Gene3D G3DSA:3.40.390.10 37 169 6.4E-29 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 DC74_RS36250 ba257f1a57729c18f3d1c67a2d06ba2d 196 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 36 171 1.6E-35 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS13795 f6c4bb4b4692e162cf40620036fb71f2 220 PANTHER PTHR18901:SF2 10 188 4.3E-41 T 23-04-2016 DC74_RS13795 f6c4bb4b4692e162cf40620036fb71f2 220 Gene3D G3DSA:1.10.150.240 26 69 7.0E-5 T 23-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 DC74_RS13795 f6c4bb4b4692e162cf40620036fb71f2 220 Gene3D G3DSA:3.40.50.1000 77 205 7.9E-37 T 23-04-2016 IPR023214 HAD-like domain DC74_RS13795 f6c4bb4b4692e162cf40620036fb71f2 220 PANTHER PTHR18901 10 188 4.3E-41 T 23-04-2016 DC74_RS13795 f6c4bb4b4692e162cf40620036fb71f2 220 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 131 185 3.9E-16 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS13795 f6c4bb4b4692e162cf40620036fb71f2 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 185 1.4E-19 T 23-04-2016 IPR023214 HAD-like domain DC74_RS13795 f6c4bb4b4692e162cf40620036fb71f2 220 SUPERFAMILY SSF56784 10 204 2.36E-39 T 23-04-2016 IPR023214 HAD-like domain DC74_RS04270 063a3a2367d607d56dcbcc81913dbc5f 305 Gene3D G3DSA:1.10.260.40 9 82 8.0E-17 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS04270 063a3a2367d607d56dcbcc81913dbc5f 305 PANTHER PTHR35010:SF2 4 289 1.3E-81 T 23-04-2016 DC74_RS04270 063a3a2367d607d56dcbcc81913dbc5f 305 PANTHER PTHR35010 4 289 1.3E-81 T 23-04-2016 DC74_RS04270 063a3a2367d607d56dcbcc81913dbc5f 305 SUPERFAMILY SSF47413 32 81 4.97E-8 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS04270 063a3a2367d607d56dcbcc81913dbc5f 305 SMART SM00530 6 83 1.1E-5 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS04270 063a3a2367d607d56dcbcc81913dbc5f 305 Pfam PF13560 Helix-turn-helix domain 10 86 2.1E-14 T 23-04-2016 DC74_RS02215 7b56c93babada659b105f8078d5c4a3a 185 Gene3D G3DSA:3.10.450.50 19 164 1.5E-27 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS02215 7b56c93babada659b105f8078d5c4a3a 185 Pfam PF13577 SnoaL-like domain 19 153 2.3E-21 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS02215 7b56c93babada659b105f8078d5c4a3a 185 SUPERFAMILY SSF54427 11 165 3.39E-25 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 Gene3D G3DSA:3.30.365.10 564 705 7.6E-52 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 Gene3D G3DSA:3.30.365.10 358 441 7.6E-52 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 SUPERFAMILY SSF56003 162 709 6.54E-149 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 Gene3D G3DSA:3.90.1170.50 13 127 5.2E-34 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 PANTHER PTHR11908:SF71 15 714 7.0E-301 T 23-04-2016 DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 159 648 6.4E-103 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 SUPERFAMILY SSF54665 11 146 8.64E-35 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 Gene3D G3DSA:3.30.365.10 203 280 1.1E-28 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 Gene3D G3DSA:3.30.365.10 128 202 7.0E-8 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 PANTHER PTHR11908 15 714 7.0E-301 T 23-04-2016 DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 Gene3D G3DSA:3.30.365.10 285 355 4.5E-6 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 Gene3D G3DSA:3.30.365.10 442 535 3.1E-19 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 29 138 2.1E-20 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS03925 ca61a60e57d3d5338f6235ab6b844f54 719 SMART SM01008 29 140 2.2E-34 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS09695 eb5349963c1504c7290ef562594298b1 195 Pfam PF14280 Domain of unknown function (DUF4365) 41 188 4.7E-24 T 23-04-2016 IPR025375 Domain of unknown function DUF4365 DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.1E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 6.1E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 6.1E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 6.1E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 6.1E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 6.1E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 183 5.4E-5 T 23-04-2016 DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 SUPERFAMILY SSF51735 6 253 1.75E-74 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 Gene3D G3DSA:3.40.50.720 4 253 1.1E-77 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 3.9E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 3.9E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 3.9E-7 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 252 6.1E-59 T 23-04-2016 DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 PANTHER PTHR24322 10 131 5.6E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39330 b063d1cd2f41d34ac662e40f8f9801d8 272 PANTHER PTHR24322 148 180 5.6E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS03170 70f51786b97d252b5a9a292cbbfd4910 124 Pfam PF13586 Transposase DDE domain 39 113 3.3E-11 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS03170 70f51786b97d252b5a9a292cbbfd4910 124 PANTHER PTHR30007:SF0 1 118 2.0E-22 T 23-04-2016 DC74_RS03170 70f51786b97d252b5a9a292cbbfd4910 124 PANTHER PTHR30007 1 118 2.0E-22 T 23-04-2016 DC74_RS10820 0400fe20a364fc697b37e554fed11c64 285 PANTHER PTHR32015 50 163 8.8E-13 T 23-04-2016 DC74_RS10820 0400fe20a364fc697b37e554fed11c64 285 SUPERFAMILY SSF53474 46 232 4.02E-29 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS10820 0400fe20a364fc697b37e554fed11c64 285 Pfam PF01674 Lipase (class 2) 50 227 9.1E-14 T 23-04-2016 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 DC74_RS10820 0400fe20a364fc697b37e554fed11c64 285 Gene3D G3DSA:3.40.50.1820 30 282 1.2E-78 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS39835 91bc9b2048a35ef36435fabf349976bc 167 SUPERFAMILY SSF46785 5 142 1.03E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39835 91bc9b2048a35ef36435fabf349976bc 167 PANTHER PTHR33204 1 159 1.2E-47 T 23-04-2016 DC74_RS39835 91bc9b2048a35ef36435fabf349976bc 167 Gene3D G3DSA:1.10.10.10 3 105 1.5E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39835 91bc9b2048a35ef36435fabf349976bc 167 Pfam PF01638 HxlR-like helix-turn-helix 19 106 1.2E-18 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS39835 91bc9b2048a35ef36435fabf349976bc 167 PANTHER PTHR33204:SF10 1 159 1.2E-47 T 23-04-2016 DC74_RS35115 357328fd48cc7699d25ed9d88ad1b47e 196 PANTHER PTHR11711:SF117 22 195 1.2E-52 T 23-04-2016 DC74_RS35115 357328fd48cc7699d25ed9d88ad1b47e 196 Pfam PF03029 Conserved hypothetical ATP binding protein 25 191 2.4E-23 T 23-04-2016 IPR004130 GPN-loop GTPase DC74_RS35115 357328fd48cc7699d25ed9d88ad1b47e 196 PANTHER PTHR11711 22 195 1.2E-52 T 23-04-2016 DC74_RS35115 357328fd48cc7699d25ed9d88ad1b47e 196 SUPERFAMILY SSF52540 20 194 3.77E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35115 357328fd48cc7699d25ed9d88ad1b47e 196 Gene3D G3DSA:3.40.50.300 18 190 7.3E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 SUPERFAMILY SSF51338 636 697 2.99E-19 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 SUPERFAMILY SSF51338 991 1020 2.99E-19 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 PANTHER PTHR11271 925 1027 5.9E-16 T 23-04-2016 DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 PANTHER PTHR11271 606 878 5.9E-16 T 23-04-2016 DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Pfam PF07676 WD40-like Beta Propeller Repeat 411 429 0.15 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Pfam PF07676 WD40-like Beta Propeller Repeat 139 181 8.8E-10 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Pfam PF07676 WD40-like Beta Propeller Repeat 497 508 0.13 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Pfam PF07676 WD40-like Beta Propeller Repeat 108 131 0.0035 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Pfam PF07676 WD40-like Beta Propeller Repeat 208 227 0.031 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Pfam PF07676 WD40-like Beta Propeller Repeat 550 565 0.0035 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Pfam PF07676 WD40-like Beta Propeller Repeat 367 381 0.18 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Gene3D G3DSA:2.30.40.10 638 698 1.2E-26 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Gene3D G3DSA:2.30.40.10 991 1032 1.2E-26 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Gene3D G3DSA:3.20.20.140 699 988 5.9E-24 T 23-04-2016 DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Pfam PF01979 Amidohydrolase family 937 1012 2.2E-10 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 SUPERFAMILY SSF51556 696 992 6.97E-30 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Gene3D G3DSA:2.120.10.30 558 628 3.9E-10 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Gene3D G3DSA:2.120.10.30 364 557 5.6E-35 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 SUPERFAMILY SSF82171 362 623 2.16E-35 T 23-04-2016 DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 Gene3D G3DSA:2.120.10.60 58 279 4.4E-41 T 23-04-2016 DC74_RS33365 0ab63f1712ad5caa51825884978ac892 1070 SUPERFAMILY SSF69304 70 276 8.37E-29 T 23-04-2016 DC74_RS05545 a8b5c320506e235f5bc0cd7d36a17df9 258 Gene3D G3DSA:3.40.50.150 20 176 8.1E-18 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS05545 a8b5c320506e235f5bc0cd7d36a17df9 258 SUPERFAMILY SSF53335 22 174 1.5E-18 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS05545 a8b5c320506e235f5bc0cd7d36a17df9 258 Pfam PF08241 Methyltransferase domain 49 125 3.1E-10 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS39280 16b94625b9ce71cfe37883d7d14df9c4 415 Pfam PF13193 AMP-binding enzyme C-terminal domain 214 287 1.7E-14 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS39280 16b94625b9ce71cfe37883d7d14df9c4 415 Gene3D G3DSA:3.40.50.980 1 116 7.5E-19 T 23-04-2016 DC74_RS39280 16b94625b9ce71cfe37883d7d14df9c4 415 PANTHER PTHR24095 1 410 1.6E-113 T 23-04-2016 DC74_RS39280 16b94625b9ce71cfe37883d7d14df9c4 415 Gene3D G3DSA:3.30.300.30 201 317 8.5E-30 T 23-04-2016 DC74_RS39280 16b94625b9ce71cfe37883d7d14df9c4 415 SMART SM00823 Phosphopantetheine attachment site 313 382 5.5E-7 T 23-04-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 DC74_RS39280 16b94625b9ce71cfe37883d7d14df9c4 415 SUPERFAMILY SSF56801 1 325 5.1E-91 T 23-04-2016 DC74_RS39280 16b94625b9ce71cfe37883d7d14df9c4 415 Pfam PF00550 Phosphopantetheine attachment site 315 378 3.8E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS39280 16b94625b9ce71cfe37883d7d14df9c4 415 Pfam PF00501 AMP-binding enzyme 1 205 2.8E-46 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS39280 16b94625b9ce71cfe37883d7d14df9c4 415 Gene3D G3DSA:1.10.1200.10 318 382 5.8E-25 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS39280 16b94625b9ce71cfe37883d7d14df9c4 415 SUPERFAMILY SSF47336 306 379 2.88E-20 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS39280 16b94625b9ce71cfe37883d7d14df9c4 415 Gene3D G3DSA:2.30.38.10 123 196 2.1E-21 T 23-04-2016 DC74_RS35730 a191aa7fbf8e8ce8ce59fef9c929f107 245 Pfam PF13936 Helix-turn-helix domain 5 45 3.9E-13 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain DC74_RS35730 a191aa7fbf8e8ce8ce59fef9c929f107 245 Gene3D G3DSA:1.10.10.10 87 166 1.6E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35730 a191aa7fbf8e8ce8ce59fef9c929f107 245 PANTHER PTHR10948 1 224 3.8E-37 T 23-04-2016 DC74_RS35730 a191aa7fbf8e8ce8ce59fef9c929f107 245 Gene3D G3DSA:1.10.10.10 5 40 8.1E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35730 a191aa7fbf8e8ce8ce59fef9c929f107 245 Pfam PF12802 MarR family 108 162 2.6E-11 T 23-04-2016 DC74_RS35730 a191aa7fbf8e8ce8ce59fef9c929f107 245 SUPERFAMILY SSF46785 88 166 3.17E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00220 4b4e2d78884315b0bac5db1c0c96bd5c 541 Pfam PF12705 PD-(D/E)XK nuclease superfamily 288 529 8.5E-16 T 23-04-2016 DC74_RS06915 083101342521dc22b8feccb2c7dd5b18 170 PRINTS PR00502 NUDIX hydrolase family signature 51 65 8.2E-8 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS06915 083101342521dc22b8feccb2c7dd5b18 170 PRINTS PR00502 NUDIX hydrolase family signature 65 80 8.2E-8 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS06915 083101342521dc22b8feccb2c7dd5b18 170 SUPERFAMILY SSF55811 27 145 7.99E-27 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS06915 083101342521dc22b8feccb2c7dd5b18 170 Gene3D G3DSA:3.90.79.10 28 143 4.0E-25 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS06915 083101342521dc22b8feccb2c7dd5b18 170 PANTHER PTHR22769 22 156 7.9E-17 T 23-04-2016 DC74_RS06915 083101342521dc22b8feccb2c7dd5b18 170 ProSitePatterns PS00893 Nudix box signature. 56 77 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS06915 083101342521dc22b8feccb2c7dd5b18 170 Pfam PF00293 NUDIX domain 29 144 1.5E-21 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS38810 8a8df3e4f9cd8e72a85509f47ad8c918 285 PANTHER PTHR30589:SF0 1 282 5.7E-107 T 23-04-2016 DC74_RS38810 8a8df3e4f9cd8e72a85509f47ad8c918 285 PANTHER PTHR30589 1 282 5.7E-107 T 23-04-2016 DC74_RS38810 8a8df3e4f9cd8e72a85509f47ad8c918 285 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 140 152 - T 23-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 DC74_RS38810 8a8df3e4f9cd8e72a85509f47ad8c918 285 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 264 15.851 T 23-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 DC74_RS38810 8a8df3e4f9cd8e72a85509f47ad8c918 285 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 259 3.1E-47 T 23-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 DC74_RS38810 8a8df3e4f9cd8e72a85509f47ad8c918 285 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 258 9.3E-66 T 23-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 DC74_RS26800 1c85b0d4e2919ed5e2c29b747577eb3f 271 Gene3D G3DSA:3.40.50.300 20 246 5.8E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS26800 1c85b0d4e2919ed5e2c29b747577eb3f 271 SMART SM00382 37 236 2.8E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS26800 1c85b0d4e2919ed5e2c29b747577eb3f 271 Pfam PF00005 ABC transporter 28 178 1.7E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS26800 1c85b0d4e2919ed5e2c29b747577eb3f 271 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS26800 1c85b0d4e2919ed5e2c29b747577eb3f 271 PANTHER PTHR24220:SF383 12 244 6.2E-97 T 23-04-2016 DC74_RS26800 1c85b0d4e2919ed5e2c29b747577eb3f 271 PANTHER PTHR24220 12 244 6.2E-97 T 23-04-2016 DC74_RS26800 1c85b0d4e2919ed5e2c29b747577eb3f 271 SUPERFAMILY SSF52540 12 243 3.4E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07925 fa31c133bf231a424264013655e1c60f 205 Pfam PF13026 Protein of unknown function (DUF3887) 108 197 9.0E-7 T 23-04-2016 IPR024981 Domain of unknown function DUF3887 KEGG: 00983+3.1.1.1|MetaCyc: PWY-6303|MetaCyc: PWY-6857 DC74_RS28570 6aa8810f8fa4ff61ecae9f3f4a258449 95 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 4.0E-24 T 23-04-2016 DC74_RS28570 6aa8810f8fa4ff61ecae9f3f4a258449 95 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 2.6E-37 T 23-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 DC74_RS28570 6aa8810f8fa4ff61ecae9f3f4a258449 95 Pfam PF00312 Ribosomal protein S15 8 88 4.2E-37 T 23-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28570 6aa8810f8fa4ff61ecae9f3f4a258449 95 SMART SM01387 8 88 3.0E-52 T 23-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28570 6aa8810f8fa4ff61ecae9f3f4a258449 95 PANTHER PTHR23321 2 89 7.2E-42 T 23-04-2016 DC74_RS28570 6aa8810f8fa4ff61ecae9f3f4a258449 95 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 23-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS28570 6aa8810f8fa4ff61ecae9f3f4a258449 95 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.122 T 23-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 DC74_RS28570 6aa8810f8fa4ff61ecae9f3f4a258449 95 Gene3D G3DSA:1.10.287.10 3 89 5.4E-39 T 23-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 DC74_RS28570 6aa8810f8fa4ff61ecae9f3f4a258449 95 SUPERFAMILY SSF47060 3 89 6.18E-35 T 23-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 DC74_RS17330 2d52c748e2402401c353b3bf89cc9af2 842 PANTHER PTHR30489 1 194 1.4E-202 T 23-04-2016 DC74_RS17330 2d52c748e2402401c353b3bf89cc9af2 842 PANTHER PTHR30489 243 842 1.4E-202 T 23-04-2016 DC74_RS17330 2d52c748e2402401c353b3bf89cc9af2 842 Pfam PF12704 MacB-like periplasmic core domain 489 679 1.2E-10 T 23-04-2016 IPR025857 MacB-like periplasmic core domain DC74_RS17330 2d52c748e2402401c353b3bf89cc9af2 842 Pfam PF12704 MacB-like periplasmic core domain 17 235 2.5E-17 T 23-04-2016 IPR025857 MacB-like periplasmic core domain DC74_RS17330 2d52c748e2402401c353b3bf89cc9af2 842 Pfam PF02687 FtsX-like permease family 271 391 1.3E-25 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS17330 2d52c748e2402401c353b3bf89cc9af2 842 Pfam PF02687 FtsX-like permease family 718 834 2.1E-20 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS17330 2d52c748e2402401c353b3bf89cc9af2 842 PANTHER PTHR30489:SF9 1 194 1.4E-202 T 23-04-2016 DC74_RS17330 2d52c748e2402401c353b3bf89cc9af2 842 PANTHER PTHR30489:SF9 243 842 1.4E-202 T 23-04-2016 DC74_RS08620 78d5c3252972235abf75f9ef65a50b0f 253 Gene3D G3DSA:1.10.10.10 5 77 2.3E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08620 78d5c3252972235abf75f9ef65a50b0f 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.1E-7 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS08620 78d5c3252972235abf75f9ef65a50b0f 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.1E-7 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS08620 78d5c3252972235abf75f9ef65a50b0f 253 PANTHER PTHR30363:SF1 1 253 1.1E-80 T 23-04-2016 DC74_RS08620 78d5c3252972235abf75f9ef65a50b0f 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 2.4E-14 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS08620 78d5c3252972235abf75f9ef65a50b0f 253 Pfam PF00455 DeoR C terminal sensor domain 75 233 3.2E-45 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain DC74_RS08620 78d5c3252972235abf75f9ef65a50b0f 253 SMART SM00420 6 58 1.4E-10 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 DC74_RS08620 78d5c3252972235abf75f9ef65a50b0f 253 Gene3D G3DSA:3.40.50.1360 78 213 1.2E-9 T 23-04-2016 DC74_RS08620 78d5c3252972235abf75f9ef65a50b0f 253 SUPERFAMILY SSF100950 74 234 2.18E-26 T 23-04-2016 DC74_RS08620 78d5c3252972235abf75f9ef65a50b0f 253 PANTHER PTHR30363 1 253 1.1E-80 T 23-04-2016 DC74_RS08620 78d5c3252972235abf75f9ef65a50b0f 253 SMART SM01134 73 234 1.7E-58 T 23-04-2016 DC74_RS08620 78d5c3252972235abf75f9ef65a50b0f 253 SUPERFAMILY SSF46785 4 73 8.47E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37625 9e89d733162eae3bfaa09ebab45197ad 426 Gene3D G3DSA:1.20.140.10 230 422 5.3E-25 T 23-04-2016 DC74_RS37625 9e89d733162eae3bfaa09ebab45197ad 426 Gene3D G3DSA:2.40.110.10 149 229 1.3E-12 T 23-04-2016 DC74_RS37625 9e89d733162eae3bfaa09ebab45197ad 426 Gene3D G3DSA:1.10.540.10 11 118 6.7E-18 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS37625 9e89d733162eae3bfaa09ebab45197ad 426 PANTHER PTHR10909 25 395 2.2E-36 T 23-04-2016 DC74_RS37625 9e89d733162eae3bfaa09ebab45197ad 426 PANTHER PTHR10909:SF274 25 395 2.2E-36 T 23-04-2016 DC74_RS37625 9e89d733162eae3bfaa09ebab45197ad 426 SUPERFAMILY SSF56645 17 236 4.06E-31 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS22470 8ce07e0fd8568386d311ef85354e7833 119 SUPERFAMILY SSF55620 2 118 2.61E-37 T 23-04-2016 DC74_RS22470 8ce07e0fd8568386d311ef85354e7833 119 Gene3D G3DSA:3.30.1130.10 2 118 2.1E-46 T 23-04-2016 DC74_RS22470 8ce07e0fd8568386d311ef85354e7833 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 116 8.1E-36 T 23-04-2016 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 DC74_RS22470 8ce07e0fd8568386d311ef85354e7833 119 Pfam PF02152 Dihydroneopterin aldolase 5 115 5.4E-36 T 23-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 DC74_RS22470 8ce07e0fd8568386d311ef85354e7833 119 SMART SM00905 4 116 1.6E-50 T 23-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 DC74_RS22470 8ce07e0fd8568386d311ef85354e7833 119 TIGRFAM TIGR00526 folB_dom: FolB domain 2 118 1.5E-32 T 23-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 DC74_RS22470 8ce07e0fd8568386d311ef85354e7833 119 PANTHER PTHR20941 2 118 1.1E-34 T 23-04-2016 DC74_RS08250 1037c418c9dc2a557505301a56b54ecb 109 SUPERFAMILY SSF50022 2 101 1.7E-29 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS08250 1037c418c9dc2a557505301a56b54ecb 109 Pfam PF00355 Rieske [2Fe-2S] domain 2 87 4.3E-16 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS08250 1037c418c9dc2a557505301a56b54ecb 109 PANTHER PTHR21496 1 100 8.2E-24 T 23-04-2016 DC74_RS08250 1037c418c9dc2a557505301a56b54ecb 109 Gene3D G3DSA:2.102.10.10 2 101 5.8E-30 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS07575 5bf8a1c62970ff6a5bfbbdd058849b23 237 SUPERFAMILY SSF52141 16 232 1.81E-87 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like DC74_RS07575 5bf8a1c62970ff6a5bfbbdd058849b23 237 SMART SM00987 62 221 1.1E-33 T 23-04-2016 DC74_RS07575 5bf8a1c62970ff6a5bfbbdd058849b23 237 SMART SM00986 62 221 1.1E-33 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like DC74_RS07575 5bf8a1c62970ff6a5bfbbdd058849b23 237 PANTHER PTHR11264 9 235 8.5E-128 T 23-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 DC74_RS07575 5bf8a1c62970ff6a5bfbbdd058849b23 237 Pfam PF03167 Uracil DNA glycosylase superfamily 67 218 2.1E-21 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like DC74_RS07575 5bf8a1c62970ff6a5bfbbdd058849b23 237 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 70 79 - T 23-04-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 DC74_RS07575 5bf8a1c62970ff6a5bfbbdd058849b23 237 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 19 224 2.9E-78 T 23-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 DC74_RS07575 5bf8a1c62970ff6a5bfbbdd058849b23 237 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 18 232 40.407 T 23-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 DC74_RS07575 5bf8a1c62970ff6a5bfbbdd058849b23 237 Gene3D G3DSA:3.40.470.10 8 233 1.7E-94 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like DC74_RS29055 e0a41e0f4fc243bc7dcb26e0218765f3 446 SUPERFAMILY SSF63411 17 229 1.25E-59 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 DC74_RS29055 e0a41e0f4fc243bc7dcb26e0218765f3 446 SUPERFAMILY SSF63411 249 434 7.67E-25 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 DC74_RS29055 e0a41e0f4fc243bc7dcb26e0218765f3 446 PANTHER PTHR11851:SF136 18 445 6.6E-133 T 23-04-2016 DC74_RS29055 e0a41e0f4fc243bc7dcb26e0218765f3 446 Pfam PF00675 Insulinase (Peptidase family M16) 26 164 3.4E-21 T 23-04-2016 IPR011765 Peptidase M16, N-terminal DC74_RS29055 e0a41e0f4fc243bc7dcb26e0218765f3 446 Pfam PF05193 Peptidase M16 inactive domain 185 364 1.5E-31 T 23-04-2016 IPR007863 Peptidase M16, C-terminal DC74_RS29055 e0a41e0f4fc243bc7dcb26e0218765f3 446 Gene3D G3DSA:3.30.830.10 19 236 8.4E-60 T 23-04-2016 IPR011237 Peptidase M16 domain GO:0046872 DC74_RS29055 e0a41e0f4fc243bc7dcb26e0218765f3 446 Gene3D G3DSA:3.30.830.10 247 427 7.6E-17 T 23-04-2016 IPR011237 Peptidase M16 domain GO:0046872 DC74_RS29055 e0a41e0f4fc243bc7dcb26e0218765f3 446 PANTHER PTHR11851 18 445 6.6E-133 T 23-04-2016 DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 Pfam PF01037 Lrp/AsnC ligand binding domain 73 146 1.0E-16 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 SMART SM00344 7 116 9.2E-38 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 Gene3D G3DSA:1.10.10.10 5 58 1.8E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 2.2E-18 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 2.2E-18 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 2.2E-18 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 23-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 PANTHER PTHR30154:SF28 1 151 2.0E-52 T 23-04-2016 DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 SUPERFAMILY SSF54909 71 150 1.74E-15 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 SUPERFAMILY SSF46785 6 66 7.52E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 54 1.8E-20 T 23-04-2016 DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 Gene3D G3DSA:3.30.70.920 59 150 1.3E-21 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS32505 c210eb437cfc69a86e4e893cbabbecad 152 PANTHER PTHR30154 1 151 2.0E-52 T 23-04-2016 DC74_RS12060 39829a6b194f2218a145ae54f31cdcf6 331 Pfam PF11271 Protein of unknown function (DUF3068) 5 305 2.0E-78 T 23-04-2016 IPR021424 Protein of unknown function DUF3068 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 303 403 1.1E-13 T 23-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 PANTHER PTHR11482:SF5 20 424 7.2E-120 T 23-04-2016 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 384 397 2.4E-20 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 285 304 2.4E-20 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 209 222 2.4E-20 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 96 108 2.4E-20 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 76 94 2.4E-20 T 23-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 SUPERFAMILY SSF50621 274 427 1.42E-44 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 76 94 - T 23-04-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 SUPERFAMILY SSF51419 43 297 1.6E-63 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 56 295 3.4E-51 T 23-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 PANTHER PTHR11482 20 424 7.2E-120 T 23-04-2016 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 23 426 1.4E-113 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 Gene3D G3DSA:3.20.20.10 56 283 2.0E-68 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 32 427 35.553 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 Gene3D G3DSA:2.40.37.10 284 426 3.1E-45 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 PRINTS PR01181 Diaminopimelate decarboxylase signature 394 416 1.9E-20 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 PRINTS PR01181 Diaminopimelate decarboxylase signature 313 331 1.9E-20 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 PRINTS PR01181 Diaminopimelate decarboxylase signature 94 111 1.9E-20 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS00635 e6ac2dc5dae462e028d697762cd26086 428 PRINTS PR01181 Diaminopimelate decarboxylase signature 183 192 1.9E-20 T 23-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS18535 47f1ef02dfb992ef5397b67232353f36 428 PANTHER PTHR10992 137 285 1.9E-80 T 23-04-2016 DC74_RS18535 47f1ef02dfb992ef5397b67232353f36 428 PANTHER PTHR10992 309 415 1.9E-80 T 23-04-2016 DC74_RS18535 47f1ef02dfb992ef5397b67232353f36 428 PANTHER PTHR10992 26 95 1.9E-80 T 23-04-2016 DC74_RS18535 47f1ef02dfb992ef5397b67232353f36 428 Pfam PF12697 Alpha/beta hydrolase family 145 407 2.0E-21 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS18535 47f1ef02dfb992ef5397b67232353f36 428 SUPERFAMILY SSF53474 141 411 7.16E-49 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS18535 47f1ef02dfb992ef5397b67232353f36 428 PANTHER PTHR10992:SF859 137 285 1.9E-80 T 23-04-2016 DC74_RS18535 47f1ef02dfb992ef5397b67232353f36 428 PANTHER PTHR10992:SF859 309 415 1.9E-80 T 23-04-2016 DC74_RS18535 47f1ef02dfb992ef5397b67232353f36 428 PANTHER PTHR10992:SF859 26 95 1.9E-80 T 23-04-2016 DC74_RS18535 47f1ef02dfb992ef5397b67232353f36 428 Gene3D G3DSA:3.40.50.1820 140 415 1.4E-54 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS11810 a6b5ef485fc75006fda32d39beb7d5b8 95 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 1 95 20.75 T 23-04-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 DC74_RS11810 a6b5ef485fc75006fda32d39beb7d5b8 95 Pfam PF13397 RNA polymerase-binding protein 1 92 4.4E-36 T 23-04-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 DC74_RS11810 a6b5ef485fc75006fda32d39beb7d5b8 95 ProSitePatterns PS00202 Rubredoxin signature. 35 45 - T 23-04-2016 IPR018527 Rubredoxin, iron-binding site GO:0046872 DC74_RS19885 5c5d29a164fd1fa68ddacabbbacc5ebe 180 SUPERFAMILY SSF53271 3 176 2.49E-36 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS19885 5c5d29a164fd1fa68ddacabbbacc5ebe 180 Gene3D G3DSA:3.40.50.2020 10 177 3.8E-48 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS19885 5c5d29a164fd1fa68ddacabbbacc5ebe 180 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 161 1.0E-35 T 23-04-2016 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS19885 5c5d29a164fd1fa68ddacabbbacc5ebe 180 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 180 24.814 T 23-04-2016 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS19885 5c5d29a164fd1fa68ddacabbbacc5ebe 180 PANTHER PTHR19278 1 177 1.9E-51 T 23-04-2016 DC74_RS19885 5c5d29a164fd1fa68ddacabbbacc5ebe 180 Pfam PF00156 Phosphoribosyl transferase domain 63 157 3.3E-11 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 DC74_RS17335 112373b6577a9a8b4ce7816f58ca60d0 436 PANTHER PTHR10108 397 432 1.7E-119 T 23-04-2016 DC74_RS17335 112373b6577a9a8b4ce7816f58ca60d0 436 PANTHER PTHR10108 75 373 1.7E-119 T 23-04-2016 DC74_RS17335 112373b6577a9a8b4ce7816f58ca60d0 436 SUPERFAMILY SSF53335 152 418 6.6E-81 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS17335 112373b6577a9a8b4ce7816f58ca60d0 436 Pfam PF02353 Mycolic acid cyclopropane synthetase 144 414 4.9E-95 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS17335 112373b6577a9a8b4ce7816f58ca60d0 436 PANTHER PTHR10108:SF743 397 432 1.7E-119 T 23-04-2016 DC74_RS17335 112373b6577a9a8b4ce7816f58ca60d0 436 PANTHER PTHR10108:SF743 75 373 1.7E-119 T 23-04-2016 DC74_RS17335 112373b6577a9a8b4ce7816f58ca60d0 436 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 161 402 0.0027 T 23-04-2016 IPR020803 Polyketide synthase, methyltransferase domain DC74_RS17335 112373b6577a9a8b4ce7816f58ca60d0 436 Gene3D G3DSA:3.40.50.150 143 416 6.7E-95 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS17335 112373b6577a9a8b4ce7816f58ca60d0 436 PIRSF PIRSF003085 4 435 3.6E-135 T 23-04-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 DC74_RS30830 f7882b4b5f632e72b626fffb01248a33 266 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS30830 f7882b4b5f632e72b626fffb01248a33 266 Gene3D G3DSA:3.40.50.300 23 228 6.3E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30830 f7882b4b5f632e72b626fffb01248a33 266 Pfam PF00005 ABC transporter 41 174 2.8E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS30830 f7882b4b5f632e72b626fffb01248a33 266 PANTHER PTHR24220:SF454 23 263 8.5E-125 T 23-04-2016 DC74_RS30830 f7882b4b5f632e72b626fffb01248a33 266 SMART SM00382 50 222 5.9E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS30830 f7882b4b5f632e72b626fffb01248a33 266 SUPERFAMILY SSF52540 24 239 3.04E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30830 f7882b4b5f632e72b626fffb01248a33 266 PANTHER PTHR24220 23 263 8.5E-125 T 23-04-2016 DC74_RS12740 f98598e30c52f9a40ec3c0de950a0a8a 406 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 392 2.9E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS12740 f98598e30c52f9a40ec3c0de950a0a8a 406 Pfam PF07730 Histidine kinase 181 221 3.8E-6 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS12740 f98598e30c52f9a40ec3c0de950a0a8a 406 Gene3D G3DSA:3.30.565.10 295 392 4.1E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS12740 f98598e30c52f9a40ec3c0de950a0a8a 406 SUPERFAMILY SSF55874 270 391 2.75E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS12740 f98598e30c52f9a40ec3c0de950a0a8a 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 373 8.7E-7 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS12740 f98598e30c52f9a40ec3c0de950a0a8a 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 346 8.7E-7 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS12740 f98598e30c52f9a40ec3c0de950a0a8a 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 391 8.7E-7 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS14130 bad3aa55e6157cf1f22139d1727e0fb6 126 Gene3D G3DSA:3.10.180.10 4 119 1.3E-11 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS14130 bad3aa55e6157cf1f22139d1727e0fb6 126 PANTHER PTHR35908 1 126 2.0E-49 T 23-04-2016 DC74_RS14130 bad3aa55e6157cf1f22139d1727e0fb6 126 SUPERFAMILY SSF54593 1 120 9.02E-17 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS14130 bad3aa55e6157cf1f22139d1727e0fb6 126 PANTHER PTHR35908:SF1 1 126 2.0E-49 T 23-04-2016 DC74_RS16300 3b98c298de99131d0bf0769f169e3d6d 155 PANTHER PTHR10681 1 153 3.6E-44 T 23-04-2016 DC74_RS16300 3b98c298de99131d0bf0769f169e3d6d 155 Pfam PF00578 AhpC/TSA family 8 134 7.0E-36 T 23-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS16300 3b98c298de99131d0bf0769f169e3d6d 155 SUPERFAMILY SSF52833 4 153 3.98E-47 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS16300 3b98c298de99131d0bf0769f169e3d6d 155 Gene3D G3DSA:3.40.30.10 2 153 3.0E-48 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS20580 fd993b32f5b89acf6dce0e2fe0dbcd7d 532 Gene3D G3DSA:2.40.260.10 370 520 1.4E-29 T 23-04-2016 IPR023365 Sortase domain DC74_RS20580 fd993b32f5b89acf6dce0e2fe0dbcd7d 532 Pfam PF04203 Sortase family 379 517 2.1E-26 T 23-04-2016 IPR005754 Sortase family DC74_RS20580 fd993b32f5b89acf6dce0e2fe0dbcd7d 532 PANTHER PTHR33393 237 530 2.4E-76 T 23-04-2016 DC74_RS20580 fd993b32f5b89acf6dce0e2fe0dbcd7d 532 SUPERFAMILY SSF63817 370 519 3.14E-30 T 23-04-2016 IPR023365 Sortase domain DC74_RS20580 fd993b32f5b89acf6dce0e2fe0dbcd7d 532 PANTHER PTHR33393:SF3 237 530 2.4E-76 T 23-04-2016 DC74_RS20580 fd993b32f5b89acf6dce0e2fe0dbcd7d 532 PANTHER PTHR33393:SF3 183 219 2.4E-76 T 23-04-2016 DC74_RS20580 fd993b32f5b89acf6dce0e2fe0dbcd7d 532 TIGRFAM TIGR01076 sortase_fam: sortase 377 517 6.2E-15 T 23-04-2016 IPR005754 Sortase family DC74_RS20580 fd993b32f5b89acf6dce0e2fe0dbcd7d 532 PANTHER PTHR33393 183 219 2.4E-76 T 23-04-2016 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 SMART SM00421 154 211 1.1E-20 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 SUPERFAMILY SSF46894 151 214 5.44E-17 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 Gene3D G3DSA:3.40.50.2300 6 156 7.6E-37 T 23-04-2016 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 2.2E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 PANTHER PTHR26402:SF151 7 210 8.6E-68 T 23-04-2016 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 SUPERFAMILY SSF52172 6 136 6.4E-30 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 PANTHER PTHR26402 7 210 8.6E-68 T 23-04-2016 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 SMART SM00448 7 120 4.5E-27 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 Pfam PF00072 Response regulator receiver domain 9 120 7.8E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 2.2E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 2.2E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 2.2E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS20360 1d2adef733ee66ea7a938c26782dc11b 219 Gene3D G3DSA:1.10.10.10 157 214 4.7E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18060 73ec77097c7ec845c3c8b140305c5303 463 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 376 386 - T 23-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site DC74_RS18060 73ec77097c7ec845c3c8b140305c5303 463 PANTHER PTHR14218 84 456 9.4E-44 T 23-04-2016 DC74_RS18060 73ec77097c7ec845c3c8b140305c5303 463 Pfam PF00082 Subtilase family 165 395 1.3E-9 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS18060 73ec77097c7ec845c3c8b140305c5303 463 Gene3D G3DSA:3.40.50.200 83 460 1.8E-75 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS18060 73ec77097c7ec845c3c8b140305c5303 463 SUPERFAMILY SSF52743 78 459 1.27E-51 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS19845 19c57accaf5b2226eac199f773a48372 450 PANTHER PTHR24421:SF26 83 450 6.8E-95 T 23-04-2016 DC74_RS19845 19c57accaf5b2226eac199f773a48372 450 Gene3D G3DSA:3.30.565.10 352 437 2.1E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS19845 19c57accaf5b2226eac199f773a48372 450 PANTHER PTHR24421 83 450 6.8E-95 T 23-04-2016 DC74_RS19845 19c57accaf5b2226eac199f773a48372 450 SUPERFAMILY SSF55874 322 435 1.13E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS19845 19c57accaf5b2226eac199f773a48372 450 Pfam PF07730 Histidine kinase 232 297 8.5E-19 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS06140 59c9f0670eaec63ff40ea51458ab7e00 221 Gene3D G3DSA:1.20.120.530 76 207 2.0E-21 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS06140 59c9f0670eaec63ff40ea51458ab7e00 221 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 4.6E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS06140 59c9f0670eaec63ff40ea51458ab7e00 221 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 4.6E-7 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS06140 59c9f0670eaec63ff40ea51458ab7e00 221 Gene3D G3DSA:1.10.10.10 10 73 6.4E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06140 59c9f0670eaec63ff40ea51458ab7e00 221 SUPERFAMILY SSF48008 78 205 9.94E-22 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS06140 59c9f0670eaec63ff40ea51458ab7e00 221 SMART SM00895 82 202 2.6E-14 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS06140 59c9f0670eaec63ff40ea51458ab7e00 221 SUPERFAMILY SSF46785 9 100 1.82E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06140 59c9f0670eaec63ff40ea51458ab7e00 221 SMART SM00345 14 72 4.1E-13 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS06140 59c9f0670eaec63ff40ea51458ab7e00 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 67 4.9E-17 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS06140 59c9f0670eaec63ff40ea51458ab7e00 221 Pfam PF07729 FCD domain 85 201 3.3E-19 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS06140 59c9f0670eaec63ff40ea51458ab7e00 221 PANTHER PTHR11751 7 98 2.9E-27 T 23-04-2016 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 Gene3D G3DSA:3.30.420.40 6 153 5.5E-48 T 23-04-2016 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 Gene3D G3DSA:3.90.640.10 181 253 9.8E-32 T 23-04-2016 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 Gene3D G3DSA:3.30.420.40 257 311 1.0E-35 T 23-04-2016 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 Gene3D G3DSA:3.30.420.40 154 180 1.0E-35 T 23-04-2016 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 PANTHER PTHR19375 3 320 1.5E-173 T 23-04-2016 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 SUPERFAMILY SSF53067 5 142 1.58E-42 T 23-04-2016 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 Pfam PF06723 MreB/Mbl protein 6 330 6.1E-156 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 43 61 4.4E-62 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 294 320 4.4E-62 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 63 86 4.4E-62 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 181 201 4.4E-62 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 126 145 4.4E-62 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 330 2.2E-153 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 SUPERFAMILY SSF53067 144 322 2.96E-51 T 23-04-2016 DC74_RS15275 b5c806119d9b2d3a994394f4ea1395e9 339 PANTHER PTHR19375:SF117 3 320 1.5E-173 T 23-04-2016 DC74_RS28335 bbf2c69422e815fb485a1acc141d8ce9 475 Pfam PF01266 FAD dependent oxidoreductase 46 409 4.1E-48 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DC74_RS28335 bbf2c69422e815fb485a1acc141d8ce9 475 Gene3D G3DSA:3.50.50.60 193 269 1.8E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28335 bbf2c69422e815fb485a1acc141d8ce9 475 Gene3D G3DSA:3.50.50.60 35 136 1.8E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28335 bbf2c69422e815fb485a1acc141d8ce9 475 Gene3D G3DSA:3.50.50.60 373 425 1.8E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28335 bbf2c69422e815fb485a1acc141d8ce9 475 PANTHER PTHR13847:SF196 3 466 8.1E-130 T 23-04-2016 DC74_RS28335 bbf2c69422e815fb485a1acc141d8ce9 475 Gene3D G3DSA:3.30.9.10 270 370 6.3E-8 T 23-04-2016 DC74_RS28335 bbf2c69422e815fb485a1acc141d8ce9 475 Gene3D G3DSA:3.30.9.10 140 192 6.3E-8 T 23-04-2016 DC74_RS28335 bbf2c69422e815fb485a1acc141d8ce9 475 SUPERFAMILY SSF51905 25 139 6.76E-39 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28335 bbf2c69422e815fb485a1acc141d8ce9 475 SUPERFAMILY SSF51905 195 325 6.76E-39 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS28335 bbf2c69422e815fb485a1acc141d8ce9 475 PANTHER PTHR13847 3 466 8.1E-130 T 23-04-2016 DC74_RS31900 b4bcb93194a7a6dbd3ba88c1353ef33c 301 PANTHER PTHR11358 72 300 2.9E-23 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS31900 b4bcb93194a7a6dbd3ba88c1353ef33c 301 Gene3D G3DSA:3.40.800.10 5 298 2.1E-47 T 23-04-2016 IPR023696 Ureohydrolase domain DC74_RS31900 b4bcb93194a7a6dbd3ba88c1353ef33c 301 PRINTS PR00116 Arginase signature 96 111 7.9E-7 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS31900 b4bcb93194a7a6dbd3ba88c1353ef33c 301 PRINTS PR00116 Arginase signature 225 254 7.9E-7 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS31900 b4bcb93194a7a6dbd3ba88c1353ef33c 301 SUPERFAMILY SSF52768 4 298 1.57E-51 T 23-04-2016 DC74_RS31900 b4bcb93194a7a6dbd3ba88c1353ef33c 301 Pfam PF00491 Arginase family 71 297 9.4E-28 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS20105 5cf9c8876425136aac548de9b55295f4 191 Pfam PF02342 TerD domain 1 187 1.1E-84 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS20105 5cf9c8876425136aac548de9b55295f4 191 Gene3D G3DSA:2.60.60.30 18 184 2.2E-74 T 23-04-2016 DC74_RS20105 5cf9c8876425136aac548de9b55295f4 191 PANTHER PTHR32097 1 191 4.5E-95 T 23-04-2016 DC74_RS27845 030021362ac02c2760d9a8a6e0dd8e0a 137 SUPERFAMILY SSF103196 2 125 2.88E-32 T 23-04-2016 DC74_RS27845 030021362ac02c2760d9a8a6e0dd8e0a 137 PANTHER PTHR36222 1 137 5.3E-56 T 23-04-2016 DC74_RS27845 030021362ac02c2760d9a8a6e0dd8e0a 137 Gene3D G3DSA:3.30.450.30 3 123 1.0E-25 T 23-04-2016 DC74_RS27845 030021362ac02c2760d9a8a6e0dd8e0a 137 Pfam PF03259 Roadblock/LC7 domain 9 99 2.0E-26 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS27845 030021362ac02c2760d9a8a6e0dd8e0a 137 SMART SM00960 9 99 1.6E-33 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS32030 0d299f8e9abe95155fc6c8bac9970783 287 Pfam PF03466 LysR substrate binding domain 87 244 6.9E-29 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS32030 0d299f8e9abe95155fc6c8bac9970783 287 Gene3D G3DSA:1.10.10.10 3 80 1.3E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32030 0d299f8e9abe95155fc6c8bac9970783 287 Gene3D G3DSA:3.40.190.10 183 242 4.7E-7 T 23-04-2016 DC74_RS32030 0d299f8e9abe95155fc6c8bac9970783 287 SUPERFAMILY SSF53850 88 245 2.06E-27 T 23-04-2016 DC74_RS32030 0d299f8e9abe95155fc6c8bac9970783 287 PANTHER PTHR30579 1 263 1.9E-89 T 23-04-2016 DC74_RS32030 0d299f8e9abe95155fc6c8bac9970783 287 SUPERFAMILY SSF46785 2 109 1.22E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32030 0d299f8e9abe95155fc6c8bac9970783 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.4E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS32030 0d299f8e9abe95155fc6c8bac9970783 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.4E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS32030 0d299f8e9abe95155fc6c8bac9970783 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.4E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS32030 0d299f8e9abe95155fc6c8bac9970783 287 Gene3D G3DSA:3.40.190.10 85 182 2.4E-20 T 23-04-2016 DC74_RS32030 0d299f8e9abe95155fc6c8bac9970783 287 PANTHER PTHR30579:SF0 1 263 1.9E-89 T 23-04-2016 DC74_RS32030 0d299f8e9abe95155fc6c8bac9970783 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 9.8E-20 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS40625 3cf41346b6104e0aef18c595248d91ba 862 PANTHER PTHR11851 10 297 1.4E-58 T 23-04-2016 DC74_RS40625 3cf41346b6104e0aef18c595248d91ba 862 SUPERFAMILY SSF63411 6 221 2.02E-40 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 DC74_RS40625 3cf41346b6104e0aef18c595248d91ba 862 Pfam PF00675 Insulinase (Peptidase family M16) 16 133 1.2E-15 T 23-04-2016 IPR011765 Peptidase M16, N-terminal DC74_RS40625 3cf41346b6104e0aef18c595248d91ba 862 PANTHER PTHR11851 726 791 1.4E-58 T 23-04-2016 DC74_RS40625 3cf41346b6104e0aef18c595248d91ba 862 Gene3D G3DSA:3.30.830.10 732 841 4.3E-6 T 23-04-2016 IPR011237 Peptidase M16 domain GO:0046872 DC74_RS40625 3cf41346b6104e0aef18c595248d91ba 862 PANTHER PTHR11851:SF136 10 297 1.4E-58 T 23-04-2016 DC74_RS40625 3cf41346b6104e0aef18c595248d91ba 862 PANTHER PTHR11851:SF136 726 791 1.4E-58 T 23-04-2016 DC74_RS40625 3cf41346b6104e0aef18c595248d91ba 862 Gene3D G3DSA:3.30.830.10 6 221 1.0E-36 T 23-04-2016 IPR011237 Peptidase M16 domain GO:0046872 DC74_RS40625 3cf41346b6104e0aef18c595248d91ba 862 Pfam PF05193 Peptidase M16 inactive domain 174 276 2.3E-12 T 23-04-2016 IPR007863 Peptidase M16, C-terminal DC74_RS40625 3cf41346b6104e0aef18c595248d91ba 862 SUPERFAMILY SSF63411 737 848 1.92E-10 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 DC74_RS40625 3cf41346b6104e0aef18c595248d91ba 862 SUPERFAMILY SSF63411 241 409 3.32E-6 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 DC74_RS34245 8d889a1f9edbe4b108786a00ca828935 361 PANTHER PTHR30036 3 347 6.9E-96 T 23-04-2016 DC74_RS34245 8d889a1f9edbe4b108786a00ca828935 361 Gene3D G3DSA:3.40.50.2300 39 150 1.5E-20 T 23-04-2016 DC74_RS34245 8d889a1f9edbe4b108786a00ca828935 361 PANTHER PTHR30036:SF1 3 347 6.9E-96 T 23-04-2016 DC74_RS34245 8d889a1f9edbe4b108786a00ca828935 361 Pfam PF13407 Periplasmic binding protein domain 69 298 3.4E-57 T 23-04-2016 IPR025997 Periplasmic binding protein DC74_RS34245 8d889a1f9edbe4b108786a00ca828935 361 Gene3D G3DSA:3.40.50.2300 151 333 1.3E-36 T 23-04-2016 DC74_RS34245 8d889a1f9edbe4b108786a00ca828935 361 SUPERFAMILY SSF53822 69 333 4.89E-56 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS38165 706644bc1bb31666e13ac241a13f21c9 175 Gene3D G3DSA:1.10.10.10 16 95 9.0E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38165 706644bc1bb31666e13ac241a13f21c9 175 Pfam PF10400 Virulence activator alpha C-term 124 172 2.6E-6 T 23-04-2016 IPR018309 Transcription regulator PadR, C-terminal DC74_RS38165 706644bc1bb31666e13ac241a13f21c9 175 Pfam PF03551 Transcriptional regulator PadR-like family 29 91 3.3E-7 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS38165 706644bc1bb31666e13ac241a13f21c9 175 SUPERFAMILY SSF46785 16 171 1.78E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34210 3dc57e7626d5f471dde81d2b941a0b3b 230 SUPERFAMILY SSF89562 7 173 1.01E-32 T 23-04-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein DC74_RS34210 3dc57e7626d5f471dde81d2b941a0b3b 230 Gene3D G3DSA:3.50.30.40 7 172 1.2E-33 T 23-04-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein DC74_RS34210 3dc57e7626d5f471dde81d2b941a0b3b 230 PANTHER PTHR33254:SF5 1 220 4.8E-27 T 23-04-2016 DC74_RS34210 3dc57e7626d5f471dde81d2b941a0b3b 230 PANTHER PTHR33254 1 220 4.8E-27 T 23-04-2016 DC74_RS34210 3dc57e7626d5f471dde81d2b941a0b3b 230 Pfam PF03737 Demethylmenaquinone methyltransferase 13 162 5.5E-23 T 23-04-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein DC74_RS23540 b70b2d6048ed16d7ad3b21586b840164 67 SUPERFAMILY SSF50249 1 64 8.12E-25 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS23540 b70b2d6048ed16d7ad3b21586b840164 67 Gene3D G3DSA:2.40.50.140 1 65 1.4E-32 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS23540 b70b2d6048ed16d7ad3b21586b840164 67 PANTHER PTHR11544 1 66 1.8E-42 T 23-04-2016 DC74_RS23540 b70b2d6048ed16d7ad3b21586b840164 67 PRINTS PR00050 Cold shock protein signature 4 19 1.2E-19 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS23540 b70b2d6048ed16d7ad3b21586b840164 67 PRINTS PR00050 Cold shock protein signature 24 33 1.2E-19 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS23540 b70b2d6048ed16d7ad3b21586b840164 67 PRINTS PR00050 Cold shock protein signature 39 57 1.2E-19 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS23540 b70b2d6048ed16d7ad3b21586b840164 67 SMART SM00357 3 66 6.2E-31 T 23-04-2016 IPR011129 Cold shock protein GO:0003676 DC74_RS23540 b70b2d6048ed16d7ad3b21586b840164 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 5.4E-31 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS23540 b70b2d6048ed16d7ad3b21586b840164 67 PIRSF PIRSF002599 1 67 4.7E-26 T 23-04-2016 IPR012156 Cold shock, CspA GO:0003676 DC74_RS23540 b70b2d6048ed16d7ad3b21586b840164 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 23-04-2016 IPR019844 Cold-shock conserved site DC74_RS20065 c87f1d4c636cd4d9872c7e687a8e176b 201 Pfam PF06737 Transglycosylase-like domain 47 119 1.2E-30 T 23-04-2016 IPR010618 Transglycosylase-like DC74_RS20065 c87f1d4c636cd4d9872c7e687a8e176b 201 Pfam PF01476 LysM domain 153 200 8.9E-5 T 23-04-2016 IPR018392 LysM domain DC74_RS20065 c87f1d4c636cd4d9872c7e687a8e176b 201 Gene3D G3DSA:3.10.350.10 151 200 1.2E-8 T 23-04-2016 IPR018392 LysM domain DC74_RS20065 c87f1d4c636cd4d9872c7e687a8e176b 201 SUPERFAMILY SSF54106 152 200 1.57E-5 T 23-04-2016 IPR018392 LysM domain DC74_RS20065 c87f1d4c636cd4d9872c7e687a8e176b 201 Gene3D G3DSA:1.10.530.10 28 122 1.9E-38 T 23-04-2016 DC74_RS20065 c87f1d4c636cd4d9872c7e687a8e176b 201 SMART SM00257 152 201 1.6E-4 T 23-04-2016 IPR018392 LysM domain DC74_RS20065 c87f1d4c636cd4d9872c7e687a8e176b 201 SUPERFAMILY SSF53955 44 121 2.41E-29 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS13970 6ddb88c9b87304e019948a4a2925ae52 220 SUPERFAMILY SSF46689 12 93 1.65E-21 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS13970 6ddb88c9b87304e019948a4a2925ae52 220 PANTHER PTHR30055:SF10 6 219 5.1E-57 T 23-04-2016 DC74_RS13970 6ddb88c9b87304e019948a4a2925ae52 220 Gene3D G3DSA:1.10.10.60 14 69 1.7E-22 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS13970 6ddb88c9b87304e019948a4a2925ae52 220 PANTHER PTHR30055 6 219 5.1E-57 T 23-04-2016 DC74_RS13970 6ddb88c9b87304e019948a4a2925ae52 220 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS13970 6ddb88c9b87304e019948a4a2925ae52 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.4E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13970 6ddb88c9b87304e019948a4a2925ae52 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.4E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13970 6ddb88c9b87304e019948a4a2925ae52 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 1.1E-17 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13970 6ddb88c9b87304e019948a4a2925ae52 220 Gene3D G3DSA:1.10.357.10 70 209 2.0E-32 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 456 4.8E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 SMART SM00388 242 308 1.8E-9 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 307 8.3E-9 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 SUPERFAMILY SSF47384 227 307 3.53E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 PANTHER PTHR24423 182 456 9.8E-74 T 23-04-2016 DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 PANTHER PTHR24423 7 19 9.8E-74 T 23-04-2016 DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 Gene3D G3DSA:3.30.565.10 346 456 1.9E-24 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 PANTHER PTHR24423:SF391 182 456 9.8E-74 T 23-04-2016 DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 PANTHER PTHR24423:SF391 7 19 9.8E-74 T 23-04-2016 DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 SMART SM00387 351 457 3.3E-23 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 SUPERFAMILY SSF55874 340 457 4.06E-26 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 Gene3D G3DSA:1.10.287.130 235 304 1.7E-8 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 4.7E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 456 4.7E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 437 4.7E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS01230 f7e05e4adb454ab5f4e394472b048af3 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 4.7E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS15440 9edc800bc6391667623a65fc220b6d8e 315 Pfam PF03466 LysR substrate binding domain 90 303 5.3E-40 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS15440 9edc800bc6391667623a65fc220b6d8e 315 SUPERFAMILY SSF53850 90 305 8.36E-35 T 23-04-2016 DC74_RS15440 9edc800bc6391667623a65fc220b6d8e 315 Gene3D G3DSA:3.40.190.10 183 276 1.0E-27 T 23-04-2016 DC74_RS15440 9edc800bc6391667623a65fc220b6d8e 315 SUPERFAMILY SSF46785 5 113 5.85E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS15440 9edc800bc6391667623a65fc220b6d8e 315 PANTHER PTHR30346:SF2 2 315 9.9E-100 T 23-04-2016 DC74_RS15440 9edc800bc6391667623a65fc220b6d8e 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 2.6E-14 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS15440 9edc800bc6391667623a65fc220b6d8e 315 Gene3D G3DSA:3.40.190.10 91 182 8.8E-19 T 23-04-2016 DC74_RS15440 9edc800bc6391667623a65fc220b6d8e 315 Gene3D G3DSA:1.10.10.10 5 85 7.6E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS15440 9edc800bc6391667623a65fc220b6d8e 315 PANTHER PTHR30346 2 315 9.9E-100 T 23-04-2016 DC74_RS26455 10e56d46af2f217b9c800623512cdb86 260 SUPERFAMILY SSF100950 2 251 5.02E-85 T 23-04-2016 DC74_RS26455 10e56d46af2f217b9c800623512cdb86 260 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 38.653 T 23-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 DC74_RS26455 10e56d46af2f217b9c800623512cdb86 260 PANTHER PTHR11280 3 258 5.0E-109 T 23-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 DC74_RS26455 10e56d46af2f217b9c800623512cdb86 260 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 16 244 5.8E-74 T 23-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 DC74_RS26455 10e56d46af2f217b9c800623512cdb86 260 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 226 3.6E-25 T 23-04-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 DC74_RS26455 10e56d46af2f217b9c800623512cdb86 260 Gene3D G3DSA:3.40.50.1360 2 242 1.7E-89 T 23-04-2016 DC74_RS26455 10e56d46af2f217b9c800623512cdb86 260 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 23-04-2016 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 DC74_RS13660 bef2651f00d2955e7617c231495e8bbe 483 SUPERFAMILY SSF53720 5 480 3.93E-150 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS13660 bef2651f00d2955e7617c231495e8bbe 483 PANTHER PTHR11699:SF212 4 482 8.7E-193 T 23-04-2016 DC74_RS13660 bef2651f00d2955e7617c231495e8bbe 483 Pfam PF00171 Aldehyde dehydrogenase family 16 476 1.8E-148 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS13660 bef2651f00d2955e7617c231495e8bbe 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS13660 bef2651f00d2955e7617c231495e8bbe 483 PANTHER PTHR11699 4 482 8.7E-193 T 23-04-2016 DC74_RS13660 bef2651f00d2955e7617c231495e8bbe 483 Gene3D G3DSA:3.40.309.10 266 443 1.6E-61 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS13660 bef2651f00d2955e7617c231495e8bbe 483 Gene3D G3DSA:3.40.605.10 8 265 4.3E-80 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS14825 548ef92f7120fb37db1e6b711e94446a 492 PANTHER PTHR23501 39 492 2.4E-185 T 23-04-2016 DC74_RS14825 548ef92f7120fb37db1e6b711e94446a 492 Pfam PF07690 Major Facilitator Superfamily 45 445 4.8E-42 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS14825 548ef92f7120fb37db1e6b711e94446a 492 SUPERFAMILY SSF103473 32 227 9.81E-56 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS14825 548ef92f7120fb37db1e6b711e94446a 492 SUPERFAMILY SSF103473 281 485 9.81E-56 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS14825 548ef92f7120fb37db1e6b711e94446a 492 PANTHER PTHR23501:SF26 39 492 2.4E-185 T 23-04-2016 DC74_RS14825 548ef92f7120fb37db1e6b711e94446a 492 Gene3D G3DSA:1.20.1250.20 294 475 2.6E-10 T 23-04-2016 DC74_RS14825 548ef92f7120fb37db1e6b711e94446a 492 Gene3D G3DSA:1.20.1250.20 41 226 4.1E-28 T 23-04-2016 DC74_RS18125 8623eb30a67e3d6b347a980ef9dbf6d3 407 SUPERFAMILY SSF53383 16 400 7.07E-108 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS18125 8623eb30a67e3d6b347a980ef9dbf6d3 407 Gene3D G3DSA:3.90.1150.10 285 403 1.5E-12 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS18125 8623eb30a67e3d6b347a980ef9dbf6d3 407 PANTHER PTHR11751:SF386 23 400 9.9E-139 T 23-04-2016 DC74_RS18125 8623eb30a67e3d6b347a980ef9dbf6d3 407 Gene3D G3DSA:3.40.640.10 68 284 8.2E-78 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS18125 8623eb30a67e3d6b347a980ef9dbf6d3 407 PANTHER PTHR11751 23 400 9.9E-139 T 23-04-2016 DC74_RS18125 8623eb30a67e3d6b347a980ef9dbf6d3 407 Pfam PF00155 Aminotransferase class I and II 63 396 6.7E-34 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS25890 87ef2ed3dcbbdd15baf984469a4c6afd 245 PANTHER PTHR30294 1 245 1.8E-79 T 23-04-2016 DC74_RS25890 87ef2ed3dcbbdd15baf984469a4c6afd 245 PANTHER PTHR30294:SF6 1 245 1.8E-79 T 23-04-2016 DC74_RS25890 87ef2ed3dcbbdd15baf984469a4c6afd 245 Pfam PF12698 ABC-2 family transporter protein 51 232 6.7E-14 T 23-04-2016 DC74_RS25890 87ef2ed3dcbbdd15baf984469a4c6afd 245 PIRSF PIRSF006648 1 243 4.6E-18 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS16400 92e26e00e8fe7df7c8824fc668175675 109 Gene3D G3DSA:3.30.1390.10 28 108 1.2E-28 T 23-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like DC74_RS16400 92e26e00e8fe7df7c8824fc668175675 109 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 34 103 3.5E-22 T 23-04-2016 IPR003769 Adaptor protein ClpS, core GO:0030163 DC74_RS16400 92e26e00e8fe7df7c8824fc668175675 109 SUPERFAMILY SSF54736 31 106 8.89E-25 T 23-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like DC74_RS16400 92e26e00e8fe7df7c8824fc668175675 109 PANTHER PTHR33473 31 109 2.3E-32 T 23-04-2016 DC74_RS16400 92e26e00e8fe7df7c8824fc668175675 109 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 18 109 17.313 T 23-04-2016 IPR022935 ATP-dependent Clp protease adaptor protein ClpS DC74_RS31860 b75ac57e3fdcee8e58252eae8c6eaf8b 64 SUPERFAMILY SSF54862 2 63 1.31E-12 T 23-04-2016 DC74_RS31860 b75ac57e3fdcee8e58252eae8c6eaf8b 64 PANTHER PTHR36923 1 63 9.5E-26 T 23-04-2016 DC74_RS31860 b75ac57e3fdcee8e58252eae8c6eaf8b 64 Pfam PF13459 4Fe-4S single cluster domain 3 61 2.0E-13 T 23-04-2016 DC74_RS31860 b75ac57e3fdcee8e58252eae8c6eaf8b 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 2.1E-7 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS31860 b75ac57e3fdcee8e58252eae8c6eaf8b 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 2.1E-7 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS31860 b75ac57e3fdcee8e58252eae8c6eaf8b 64 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 2.1E-7 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS31860 b75ac57e3fdcee8e58252eae8c6eaf8b 64 Gene3D G3DSA:3.30.70.20 1 63 2.2E-15 T 23-04-2016 DC74_RS31860 b75ac57e3fdcee8e58252eae8c6eaf8b 64 PANTHER PTHR36923:SF1 1 63 9.5E-26 T 23-04-2016 DC74_RS26450 fff3ba16fd0981373f0a79e4dd9040da 508 Gene3D G3DSA:3.20.20.300 19 337 2.3E-95 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS26450 fff3ba16fd0981373f0a79e4dd9040da 508 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 41 335 2.1E-75 T 23-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 DC74_RS26450 fff3ba16fd0981373f0a79e4dd9040da 508 PANTHER PTHR30480 7 339 4.3E-113 T 23-04-2016 DC74_RS26450 fff3ba16fd0981373f0a79e4dd9040da 508 SUPERFAMILY SSF51445 21 338 9.69E-82 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS26450 fff3ba16fd0981373f0a79e4dd9040da 508 PANTHER PTHR30480:SF2 7 339 4.3E-113 T 23-04-2016 DC74_RS05350 db91cd0215db806cebce31c1bca783f6 159 SUPERFAMILY SSF49503 21 139 3.58E-11 T 23-04-2016 IPR008972 Cupredoxin DC74_RS05350 db91cd0215db806cebce31c1bca783f6 159 Gene3D G3DSA:2.60.40.420 42 140 2.3E-13 T 23-04-2016 IPR008972 Cupredoxin DC74_RS16980 e1c7ca078d8aa648a0381e2e23c22428 1284 Gene3D G3DSA:3.90.550.10 26 105 4.0E-30 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS16980 e1c7ca078d8aa648a0381e2e23c22428 1284 Gene3D G3DSA:3.90.550.10 142 277 4.0E-30 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS16980 e1c7ca078d8aa648a0381e2e23c22428 1284 PANTHER PTHR22916:SF29 1 99 1.7E-169 T 23-04-2016 DC74_RS16980 e1c7ca078d8aa648a0381e2e23c22428 1284 PANTHER PTHR22916:SF29 135 547 1.7E-169 T 23-04-2016 DC74_RS16980 e1c7ca078d8aa648a0381e2e23c22428 1284 PANTHER PTHR22916 1 99 1.7E-169 T 23-04-2016 DC74_RS16980 e1c7ca078d8aa648a0381e2e23c22428 1284 PANTHER PTHR22916 135 547 1.7E-169 T 23-04-2016 DC74_RS16980 e1c7ca078d8aa648a0381e2e23c22428 1284 SUPERFAMILY SSF53448 24 102 5.47E-33 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS16980 e1c7ca078d8aa648a0381e2e23c22428 1284 SUPERFAMILY SSF53448 141 277 5.47E-33 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS16980 e1c7ca078d8aa648a0381e2e23c22428 1284 Pfam PF13641 Glycosyltransferase like family 2 26 277 6.8E-18 T 23-04-2016 DC74_RS33590 1f675d793f10e5c1f2d77259ee3fe383 263 PANTHER PTHR10992 2 263 1.3E-20 T 23-04-2016 DC74_RS33590 1f675d793f10e5c1f2d77259ee3fe383 263 SUPERFAMILY SSF53474 5 260 9.26E-33 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS33590 1f675d793f10e5c1f2d77259ee3fe383 263 Pfam PF12697 Alpha/beta hydrolase family 22 255 6.4E-21 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS33590 1f675d793f10e5c1f2d77259ee3fe383 263 Gene3D G3DSA:3.40.50.1820 6 261 5.9E-31 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS12760 aeb673057138d5803baf42b2e9a09e5a 259 SUPERFAMILY SSF56219 25 252 1.07E-25 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS12760 aeb673057138d5803baf42b2e9a09e5a 259 Gene3D G3DSA:3.60.10.10 27 180 2.6E-6 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS12760 aeb673057138d5803baf42b2e9a09e5a 259 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 30 246 1.2E-13 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS16240 e4887ce1ef8b6df36421ce7a6000faff 69 Pfam PF11755 Protein of unknown function (DUF3311) 3 61 1.4E-16 T 23-04-2016 IPR021741 Protein of unknown function DUF3311 DC74_RS11605 3a1e5ae5fce49c42f1e00c9b2b11f353 234 PANTHER PTHR13887:SF10 1 212 4.9E-52 T 23-04-2016 DC74_RS11605 3a1e5ae5fce49c42f1e00c9b2b11f353 234 Pfam PF01323 DSBA-like thioredoxin domain 2 205 6.7E-44 T 23-04-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 DC74_RS11605 3a1e5ae5fce49c42f1e00c9b2b11f353 234 SUPERFAMILY SSF52833 1 210 1.49E-44 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS11605 3a1e5ae5fce49c42f1e00c9b2b11f353 234 Gene3D G3DSA:3.40.30.10 1 206 1.3E-45 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS11605 3a1e5ae5fce49c42f1e00c9b2b11f353 234 PANTHER PTHR13887 1 212 4.9E-52 T 23-04-2016 DC74_RS33230 e14116e546d2b8e4dde966e98da118ce 679 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 52 336 9.9E-122 T 23-04-2016 IPR032697 Squalene cyclase, N-terminal DC74_RS33230 e14116e546d2b8e4dde966e98da118ce 679 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 52 662 1.6E-185 T 23-04-2016 IPR018333 Squalene cyclase GO:0016866 DC74_RS33230 e14116e546d2b8e4dde966e98da118ce 679 SUPERFAMILY SSF48239 335 664 8.63E-105 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS33230 e14116e546d2b8e4dde966e98da118ce 679 Gene3D G3DSA:1.50.10.20 73 331 3.4E-65 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS33230 e14116e546d2b8e4dde966e98da118ce 679 PANTHER PTHR11764 42 672 0.0 T 23-04-2016 DC74_RS33230 e14116e546d2b8e4dde966e98da118ce 679 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 44 664 5.4E-237 T 23-04-2016 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072|UniPathway: UPA00337 DC74_RS33230 e14116e546d2b8e4dde966e98da118ce 679 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 347 663 1.4E-136 T 23-04-2016 IPR032696 Squalene cyclase, C-terminal DC74_RS33230 e14116e546d2b8e4dde966e98da118ce 679 SUPERFAMILY SSF48239 75 341 3.56E-72 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS33230 e14116e546d2b8e4dde966e98da118ce 679 Gene3D G3DSA:1.50.10.20 332 663 6.0E-113 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS33230 e14116e546d2b8e4dde966e98da118ce 679 PANTHER PTHR11764:SF12 42 672 0.0 T 23-04-2016 DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 PANTHER PTHR10992 416 523 8.6E-50 T 23-04-2016 DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 PANTHER PTHR10992 314 346 8.6E-50 T 23-04-2016 DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 PANTHER PTHR10992 51 173 8.6E-50 T 23-04-2016 DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 PANTHER PTHR10992 220 286 8.6E-50 T 23-04-2016 DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 Gene3D G3DSA:3.40.50.1820 89 174 5.0E-59 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 Gene3D G3DSA:3.40.50.1820 401 521 5.0E-59 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 Gene3D G3DSA:3.40.50.1820 218 342 5.0E-59 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 PANTHER PTHR10992:SF863 416 523 8.6E-50 T 23-04-2016 DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 PANTHER PTHR10992:SF863 314 346 8.6E-50 T 23-04-2016 DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 PANTHER PTHR10992:SF863 51 173 8.6E-50 T 23-04-2016 DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 PANTHER PTHR10992:SF863 220 286 8.6E-50 T 23-04-2016 DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 Pfam PF00561 alpha/beta hydrolase fold 125 506 2.1E-36 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 SUPERFAMILY SSF53474 376 521 5.0E-24 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 SUPERFAMILY SSF53474 119 175 5.0E-24 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS22215 58f8d728fc124bb57a84603ef1194ba7 534 SUPERFAMILY SSF53474 220 274 5.0E-24 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 Gene3D G3DSA:3.30.365.10 356 442 2.1E-56 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 Gene3D G3DSA:3.30.365.10 561 706 2.1E-56 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 33 136 1.6E-16 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 SMART SM01008 33 137 9.9E-33 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 PANTHER PTHR11908 19 712 2.8E-300 T 23-04-2016 DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 PANTHER PTHR11908:SF71 19 712 2.8E-300 T 23-04-2016 DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 Gene3D G3DSA:3.30.365.10 125 175 3.0E-10 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 Gene3D G3DSA:3.30.365.10 283 329 3.0E-10 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 SUPERFAMILY SSF54665 17 142 2.62E-35 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 Gene3D G3DSA:3.90.1170.50 8 124 4.6E-31 T 23-04-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 Gene3D G3DSA:3.30.365.10 443 555 9.8E-26 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 SUPERFAMILY SSF56003 145 706 8.64E-156 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 Gene3D G3DSA:3.30.365.10 176 275 6.1E-36 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 540 647 5.6E-24 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS30960 bfa6f3b1da1ee98dd87db8c066d14751 712 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 162 537 1.4E-85 T 23-04-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DC74_RS31210 3fa0a0374e0379ca17e2a7be9bff79f4 513 Gene3D G3DSA:3.30.300.30 405 505 8.0E-34 T 23-04-2016 DC74_RS31210 3fa0a0374e0379ca17e2a7be9bff79f4 513 Gene3D G3DSA:2.30.38.10 351 404 1.5E-14 T 23-04-2016 DC74_RS31210 3fa0a0374e0379ca17e2a7be9bff79f4 513 Gene3D G3DSA:3.40.50.980 169 320 3.0E-35 T 23-04-2016 DC74_RS31210 3fa0a0374e0379ca17e2a7be9bff79f4 513 SUPERFAMILY SSF56801 4 506 1.57E-132 T 23-04-2016 DC74_RS31210 3fa0a0374e0379ca17e2a7be9bff79f4 513 Gene3D G3DSA:3.40.50.980 37 168 9.2E-29 T 23-04-2016 DC74_RS31210 3fa0a0374e0379ca17e2a7be9bff79f4 513 PANTHER PTHR24095 39 506 7.1E-137 T 23-04-2016 DC74_RS31210 3fa0a0374e0379ca17e2a7be9bff79f4 513 Pfam PF00501 AMP-binding enzyme 37 410 3.2E-85 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS31210 3fa0a0374e0379ca17e2a7be9bff79f4 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 494 1.4E-22 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS11275 256e94dff3d6a39f0f2e5fe8fb514fed 215 Pfam PF00881 Nitroreductase family 25 193 5.0E-23 T 23-04-2016 IPR029479 Nitroreductase DC74_RS11275 256e94dff3d6a39f0f2e5fe8fb514fed 215 SUPERFAMILY SSF55469 16 213 1.13E-41 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS11275 256e94dff3d6a39f0f2e5fe8fb514fed 215 PANTHER PTHR23026 1 211 3.0E-53 T 23-04-2016 DC74_RS11275 256e94dff3d6a39f0f2e5fe8fb514fed 215 PANTHER PTHR23026:SF90 1 211 3.0E-53 T 23-04-2016 DC74_RS11275 256e94dff3d6a39f0f2e5fe8fb514fed 215 Gene3D G3DSA:3.40.109.10 18 213 1.9E-46 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS18180 8d246387b92044a5aab3643c0ce7d531 490 Pfam PF00171 Aldehyde dehydrogenase family 18 485 2.2E-155 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS18180 8d246387b92044a5aab3643c0ce7d531 490 PANTHER PTHR11699 12 487 1.3E-176 T 23-04-2016 DC74_RS18180 8d246387b92044a5aab3643c0ce7d531 490 Gene3D G3DSA:3.40.605.10 10 275 7.7E-80 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS18180 8d246387b92044a5aab3643c0ce7d531 490 SUPERFAMILY SSF53720 10 488 3.53E-147 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS18180 8d246387b92044a5aab3643c0ce7d531 490 Gene3D G3DSA:3.40.309.10 276 461 1.2E-64 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS38105 758116d7fa9926289ff304e98ce99b30 148 SMART SM00347 31 132 1.1E-20 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS38105 758116d7fa9926289ff304e98ce99b30 148 Gene3D G3DSA:1.10.10.10 37 101 6.9E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38105 758116d7fa9926289ff304e98ce99b30 148 PANTHER PTHR33164:SF2 17 148 9.9E-49 T 23-04-2016 DC74_RS38105 758116d7fa9926289ff304e98ce99b30 148 SUPERFAMILY SSF46785 7 144 5.46E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38105 758116d7fa9926289ff304e98ce99b30 148 PANTHER PTHR33164 17 148 9.9E-49 T 23-04-2016 DC74_RS38105 758116d7fa9926289ff304e98ce99b30 148 Pfam PF01047 MarR family 38 95 7.8E-13 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS38105 758116d7fa9926289ff304e98ce99b30 148 Gene3D G3DSA:1.10.287.100 103 146 5.4E-14 T 23-04-2016 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 DC74_RS05585 77dfc2a6df48ca4202557990c2e32eec 194 Gene3D G3DSA:3.40.250.10 5 114 4.5E-29 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS05585 77dfc2a6df48ca4202557990c2e32eec 194 Pfam PF00581 Rhodanese-like domain 16 105 1.0E-14 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS05585 77dfc2a6df48ca4202557990c2e32eec 194 SUPERFAMILY SSF52821 4 114 1.44E-32 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS05585 77dfc2a6df48ca4202557990c2e32eec 194 ProSitePatterns PS00380 Rhodanese signature 1. 37 48 - T 23-04-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 DC74_RS05585 77dfc2a6df48ca4202557990c2e32eec 194 SMART SM00450 12 109 1.0E-21 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS05585 77dfc2a6df48ca4202557990c2e32eec 194 Pfam PF11127 Protein of unknown function (DUF2892) 119 172 8.4E-10 T 23-04-2016 IPR021309 Protein of unknown function DUF2892 DC74_RS05585 77dfc2a6df48ca4202557990c2e32eec 194 PANTHER PTHR12231 24 113 8.6E-15 T 23-04-2016 DC74_RS01050 d50675daf7a78269bcf13b8d6d5237bb 286 Gene3D G3DSA:3.40.50.1820 6 283 8.5E-33 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01050 d50675daf7a78269bcf13b8d6d5237bb 286 Pfam PF12697 Alpha/beta hydrolase family 9 266 3.4E-16 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS01050 d50675daf7a78269bcf13b8d6d5237bb 286 SUPERFAMILY SSF53474 7 280 6.02E-27 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01050 d50675daf7a78269bcf13b8d6d5237bb 286 PANTHER PTHR10992 72 135 8.0E-20 T 23-04-2016 DC74_RS01050 d50675daf7a78269bcf13b8d6d5237bb 286 PANTHER PTHR10992 166 247 8.0E-20 T 23-04-2016 DC74_RS01050 d50675daf7a78269bcf13b8d6d5237bb 286 PANTHER PTHR10992 7 51 8.0E-20 T 23-04-2016 DC74_RS27730 d5b785a2650b619d6400595f8360173d 546 Pfam PF00171 Aldehyde dehydrogenase family 55 530 9.7E-104 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS27730 d5b785a2650b619d6400595f8360173d 546 Gene3D G3DSA:3.40.605.10 41 302 1.3E-64 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS27730 d5b785a2650b619d6400595f8360173d 546 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 12 545 2.2E-242 T 23-04-2016 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0006537|GO:0006561 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|UniPathway: UPA00261 DC74_RS27730 d5b785a2650b619d6400595f8360173d 546 PANTHER PTHR11699 22 545 9.3E-258 T 23-04-2016 DC74_RS27730 d5b785a2650b619d6400595f8360173d 546 Gene3D G3DSA:3.40.309.10 303 504 9.1E-43 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS27730 d5b785a2650b619d6400595f8360173d 546 SUPERFAMILY SSF53720 8 531 1.02E-123 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS27730 d5b785a2650b619d6400595f8360173d 546 PANTHER PTHR11699:SF18 22 545 9.3E-258 T 23-04-2016 DC74_RS27730 d5b785a2650b619d6400595f8360173d 546 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 321 332 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS14745 983e7529342e9402f3b4bb7d3c853d24 398 Gene3D G3DSA:3.40.190.10 127 287 1.4E-35 T 23-04-2016 DC74_RS14745 983e7529342e9402f3b4bb7d3c853d24 398 PANTHER PTHR30061 33 395 2.0E-48 T 23-04-2016 DC74_RS14745 983e7529342e9402f3b4bb7d3c853d24 398 Pfam PF01547 Bacterial extracellular solute-binding protein 34 300 1.6E-28 T 23-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 DC74_RS14745 983e7529342e9402f3b4bb7d3c853d24 398 Gene3D G3DSA:3.40.190.10 288 341 1.4E-22 T 23-04-2016 DC74_RS14745 983e7529342e9402f3b4bb7d3c853d24 398 Gene3D G3DSA:3.40.190.10 22 126 1.4E-22 T 23-04-2016 DC74_RS14745 983e7529342e9402f3b4bb7d3c853d24 398 SUPERFAMILY SSF53850 3 394 5.33E-59 T 23-04-2016 DC74_RS38860 a747e28ff8c3387f4649fd981fccf06b 536 Gene3D G3DSA:1.20.200.10 206 530 3.4E-108 T 23-04-2016 DC74_RS38860 a747e28ff8c3387f4649fd981fccf06b 536 Pfam PF00221 Aromatic amino acid lyase 19 497 1.1E-164 T 23-04-2016 IPR001106 Aromatic amino acid lyase DC74_RS38860 a747e28ff8c3387f4649fd981fccf06b 536 SUPERFAMILY SSF48557 7 530 1.41E-172 T 23-04-2016 IPR008948 L-Aspartase-like GO:0003824 DC74_RS38860 a747e28ff8c3387f4649fd981fccf06b 536 PANTHER PTHR10362 10 523 9.6E-174 T 23-04-2016 DC74_RS38860 a747e28ff8c3387f4649fd981fccf06b 536 TIGRFAM TIGR03832 Tyr_2_3_mutase: tyrosine 2,3-aminomutase 14 518 9.4E-282 T 23-04-2016 IPR022314 Tyrosine 2,3-aminomutase, putative KEGG: 00350+5.4.3.6+4.3.1.23 DC74_RS38860 a747e28ff8c3387f4649fd981fccf06b 536 PANTHER PTHR10362:SF7 10 523 9.6E-174 T 23-04-2016 DC74_RS38860 a747e28ff8c3387f4649fd981fccf06b 536 Gene3D G3DSA:1.10.275.10 6 205 1.6E-64 T 23-04-2016 IPR024083 Fumarase/histidase, N-terminal DC74_RS38985 ef400858af6c8a4e2cbbc36098b875da 373 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 279 7.6E-43 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS38985 ef400858af6c8a4e2cbbc36098b875da 373 PANTHER PTHR10366 2 369 6.5E-135 T 23-04-2016 DC74_RS38985 ef400858af6c8a4e2cbbc36098b875da 373 PANTHER PTHR10366:SF367 2 369 6.5E-135 T 23-04-2016 DC74_RS38985 ef400858af6c8a4e2cbbc36098b875da 373 SUPERFAMILY SSF51735 1 123 4.53E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38985 ef400858af6c8a4e2cbbc36098b875da 373 SUPERFAMILY SSF51735 160 344 4.53E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38985 ef400858af6c8a4e2cbbc36098b875da 373 Gene3D G3DSA:3.40.50.720 165 342 1.0E-68 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38985 ef400858af6c8a4e2cbbc36098b875da 373 Gene3D G3DSA:3.40.50.720 1 132 1.0E-68 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29885 fcfd28d9103a94d8d0943f1e7f86c1a1 228 Gene3D G3DSA:3.40.50.300 3 221 1.4E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29885 fcfd28d9103a94d8d0943f1e7f86c1a1 228 SUPERFAMILY SSF52540 3 221 1.94E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29885 fcfd28d9103a94d8d0943f1e7f86c1a1 228 Pfam PF00005 ABC transporter 22 171 4.3E-35 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS29885 fcfd28d9103a94d8d0943f1e7f86c1a1 228 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS29885 fcfd28d9103a94d8d0943f1e7f86c1a1 228 PANTHER PTHR24220 4 220 4.0E-80 T 23-04-2016 DC74_RS29885 fcfd28d9103a94d8d0943f1e7f86c1a1 228 SMART SM00382 31 219 9.1E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS04485 948a485e880f5b50607a8af20515a750 77 SUPERFAMILY SSF53474 3 68 3.95E-13 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS04485 948a485e880f5b50607a8af20515a750 77 Gene3D G3DSA:3.40.50.1820 2 71 1.7E-9 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS23070 89db532ba031db1b02813cdf2dacb6a4 328 PANTHER PTHR11732 4 323 1.3E-153 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS23070 89db532ba031db1b02813cdf2dacb6a4 328 SUPERFAMILY SSF51430 7 308 7.6E-102 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS23070 89db532ba031db1b02813cdf2dacb6a4 328 PANTHER PTHR11732:SF225 4 323 1.3E-153 T 23-04-2016 DC74_RS23070 89db532ba031db1b02813cdf2dacb6a4 328 Gene3D G3DSA:3.20.20.100 4 321 3.2E-118 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS23070 89db532ba031db1b02813cdf2dacb6a4 328 Pfam PF00248 Aldo/keto reductase family 18 307 1.2E-77 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS23370 c71fc60794fd8e5d6f0df70b38be5fa8 280 SUPERFAMILY SSF56112 128 230 5.1E-5 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS37290 4754ae4f8bfd9153c0602aee84e8b36a 526 Gene3D G3DSA:3.20.20.70 6 390 2.2E-127 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS37290 4754ae4f8bfd9153c0602aee84e8b36a 526 PANTHER PTHR10277 2 432 3.1E-179 T 23-04-2016 DC74_RS37290 4754ae4f8bfd9153c0602aee84e8b36a 526 PANTHER PTHR10277:SF28 2 432 3.1E-179 T 23-04-2016 DC74_RS37290 4754ae4f8bfd9153c0602aee84e8b36a 526 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 35 51 - T 23-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS37290 4754ae4f8bfd9153c0602aee84e8b36a 526 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 238 251 - T 23-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 DC74_RS37290 4754ae4f8bfd9153c0602aee84e8b36a 526 Pfam PF00682 HMGL-like 28 308 4.5E-66 T 23-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 DC74_RS37290 4754ae4f8bfd9153c0602aee84e8b36a 526 SUPERFAMILY SSF51569 17 325 1.25E-90 T 23-04-2016 DC74_RS37290 4754ae4f8bfd9153c0602aee84e8b36a 526 SUPERFAMILY SSF89000 385 433 1.33E-8 T 23-04-2016 DC74_RS07835 7581e793ddb9efa750f52e9312aef6c2 147 SUPERFAMILY SSF46689 67 117 2.82E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07835 7581e793ddb9efa750f52e9312aef6c2 147 Gene3D G3DSA:1.10.10.60 70 117 2.5E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07835 7581e793ddb9efa750f52e9312aef6c2 147 PANTHER PTHR11019 12 122 2.7E-32 T 23-04-2016 DC74_RS07835 7581e793ddb9efa750f52e9312aef6c2 147 SMART SM00342 31 114 1.6E-31 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS07835 7581e793ddb9efa750f52e9312aef6c2 147 Gene3D G3DSA:1.10.10.60 15 69 5.6E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07835 7581e793ddb9efa750f52e9312aef6c2 147 Pfam PF12833 Helix-turn-helix domain 37 116 1.3E-22 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS07835 7581e793ddb9efa750f52e9312aef6c2 147 SUPERFAMILY SSF46689 16 65 2.51E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS13765 d07f281cfae9aaa5cf1dc4f4c748f94b 278 PANTHER PTHR10245:SF7 13 278 1.2E-39 T 23-04-2016 DC74_RS13765 d07f281cfae9aaa5cf1dc4f4c748f94b 278 Gene3D G3DSA:1.10.260.40 14 69 3.7E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS13765 d07f281cfae9aaa5cf1dc4f4c748f94b 278 SMART SM00530 19 74 3.7E-7 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS13765 d07f281cfae9aaa5cf1dc4f4c748f94b 278 PANTHER PTHR10245 13 278 1.2E-39 T 23-04-2016 DC74_RS13765 d07f281cfae9aaa5cf1dc4f4c748f94b 278 Pfam PF13560 Helix-turn-helix domain 16 69 4.4E-14 T 23-04-2016 DC74_RS13765 d07f281cfae9aaa5cf1dc4f4c748f94b 278 SUPERFAMILY SSF47413 15 67 8.16E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS35050 b3be31244c6e42478577851781d1a5fc 259 Pfam PF09335 SNARE associated Golgi protein 104 221 8.1E-27 T 23-04-2016 IPR032816 SNARE associated Golgi protein DC74_RS35050 b3be31244c6e42478577851781d1a5fc 259 PANTHER PTHR12677 16 258 2.0E-34 T 23-04-2016 IPR015414 Transmembrane protein TMEM64/TMEM41 GO:0016021 DC74_RS18685 3f50ccf8806a6bca0e8002ce123e4350 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 7.8E-54 T 23-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 DC74_RS18685 3f50ccf8806a6bca0e8002ce123e4350 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 5.1E-57 T 23-04-2016 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 DC74_RS18685 3f50ccf8806a6bca0e8002ce123e4350 122 SMART SM01374 1 122 1.9E-87 T 23-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 DC74_RS18685 3f50ccf8806a6bca0e8002ce123e4350 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.242 T 23-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 DC74_RS18685 3f50ccf8806a6bca0e8002ce123e4350 122 Gene3D G3DSA:2.40.150.20 2 122 2.5E-53 T 23-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 DC74_RS18685 3f50ccf8806a6bca0e8002ce123e4350 122 PANTHER PTHR11761 2 122 1.0E-76 T 23-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 DC74_RS18685 3f50ccf8806a6bca0e8002ce123e4350 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 23-04-2016 IPR019972 Ribosomal protein L14P, conserved site DC74_RS18685 3f50ccf8806a6bca0e8002ce123e4350 122 SUPERFAMILY SSF50193 2 122 3.01E-50 T 23-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 DC74_RS14165 e78ac65621cc28845085f615ed869c5e 242 Gene3D G3DSA:3.40.50.150 24 211 4.0E-37 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14165 e78ac65621cc28845085f615ed869c5e 242 SUPERFAMILY SSF53335 23 216 1.43E-39 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14165 e78ac65621cc28845085f615ed869c5e 242 Pfam PF13489 Methyltransferase domain 23 201 2.7E-20 T 23-04-2016 DC74_RS14165 e78ac65621cc28845085f615ed869c5e 242 PANTHER PTHR10108 21 220 3.4E-28 T 23-04-2016 DC74_RS17430 6c81c83ec7c29b32afacb563b6330c2a 263 Gene3D G3DSA:2.60.40.1240 141 260 1.1E-7 T 23-04-2016 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain DC74_RS17430 6c81c83ec7c29b32afacb563b6330c2a 263 Pfam PF11611 Domain of unknown function (DUF4352) 145 253 5.7E-9 T 23-04-2016 IPR029051 Domain of unknown function DUF4352 DC74_RS09460 1818e35b871589d83f5ea22e9947893b 212 PANTHER PTHR11608 11 189 5.6E-89 T 23-04-2016 DC74_RS09460 1818e35b871589d83f5ea22e9947893b 212 Gene3D G3DSA:3.40.50.2020 19 181 4.6E-50 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS09460 1818e35b871589d83f5ea22e9947893b 212 Pfam PF00156 Phosphoribosyl transferase domain 18 157 7.4E-22 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 DC74_RS09460 1818e35b871589d83f5ea22e9947893b 212 SUPERFAMILY SSF53271 16 181 9.96E-41 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS09460 1818e35b871589d83f5ea22e9947893b 212 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 14 187 36.766 T 23-04-2016 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 DC74_RS08085 2641c80eb1806e972955f430d724078a 472 Gene3D G3DSA:3.30.1490.100 235 340 1.2E-30 T 23-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS08085 2641c80eb1806e972955f430d724078a 472 Pfam PF11799 impB/mucB/samB family C-terminal domain 230 335 7.6E-20 T 23-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS08085 2641c80eb1806e972955f430d724078a 472 Gene3D G3DSA:3.30.70.270 57 157 7.9E-26 T 23-04-2016 DC74_RS08085 2641c80eb1806e972955f430d724078a 472 SUPERFAMILY SSF100879 232 332 1.0E-26 T 23-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS08085 2641c80eb1806e972955f430d724078a 472 Gene3D G3DSA:1.10.150.20 159 228 3.4E-21 T 23-04-2016 DC74_RS08085 2641c80eb1806e972955f430d724078a 472 Pfam PF00817 impB/mucB/samB family 1 147 1.2E-44 T 23-04-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS08085 2641c80eb1806e972955f430d724078a 472 PANTHER PTHR11076 1 335 1.6E-118 T 23-04-2016 DC74_RS08085 2641c80eb1806e972955f430d724078a 472 Hamap MF_01113 DNA polymerase IV [dinB]. 1 347 33.108 T 23-04-2016 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS08085 2641c80eb1806e972955f430d724078a 472 Pfam PF11798 IMS family HHH motif 160 190 1.4E-5 T 23-04-2016 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS08085 2641c80eb1806e972955f430d724078a 472 SUPERFAMILY SSF56672 1 228 4.09E-69 T 23-04-2016 DC74_RS36930 558f24dbd0ff8fa02bd2694d07f3908e 578 SUPERFAMILY SSF90123 4 293 1.57E-31 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS36930 558f24dbd0ff8fa02bd2694d07f3908e 578 Gene3D G3DSA:1.20.1560.10 5 291 1.0E-22 T 23-04-2016 DC74_RS36930 558f24dbd0ff8fa02bd2694d07f3908e 578 Pfam PF00664 ABC transporter transmembrane region 30 284 7.5E-7 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS38695 06540caf77e4ca0e5c44e1d7b36f7e99 344 Gene3D G3DSA:3.90.25.10 205 334 1.4E-45 T 23-04-2016 DC74_RS38695 06540caf77e4ca0e5c44e1d7b36f7e99 344 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 331 50.007 T 23-04-2016 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|UniPathway: UPA00128 DC74_RS38695 06540caf77e4ca0e5c44e1d7b36f7e99 344 SUPERFAMILY SSF51735 3 327 1.36E-74 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38695 06540caf77e4ca0e5c44e1d7b36f7e99 344 PANTHER PTHR10366:SF32 4 334 1.0E-162 T 23-04-2016 DC74_RS38695 06540caf77e4ca0e5c44e1d7b36f7e99 344 Gene3D G3DSA:3.40.50.720 3 204 4.0E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38695 06540caf77e4ca0e5c44e1d7b36f7e99 344 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 321 2.6E-118 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38695 06540caf77e4ca0e5c44e1d7b36f7e99 344 PANTHER PTHR10366 4 334 1.0E-162 T 23-04-2016 DC74_RS37275 43c3f7703812388ed9a95a5f43afe0e6 241 PANTHER PTHR24421 60 238 5.4E-25 T 23-04-2016 DC74_RS37275 43c3f7703812388ed9a95a5f43afe0e6 241 SMART SM00387 146 240 2.1E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS37275 43c3f7703812388ed9a95a5f43afe0e6 241 Gene3D G3DSA:3.30.565.10 101 239 7.4E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS37275 43c3f7703812388ed9a95a5f43afe0e6 241 PRINTS PR00344 Bacterial sensor protein C-terminal signature 182 196 3.6E-5 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS37275 43c3f7703812388ed9a95a5f43afe0e6 241 PRINTS PR00344 Bacterial sensor protein C-terminal signature 200 218 3.6E-5 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS37275 43c3f7703812388ed9a95a5f43afe0e6 241 PRINTS PR00344 Bacterial sensor protein C-terminal signature 224 237 3.6E-5 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS37275 43c3f7703812388ed9a95a5f43afe0e6 241 SUPERFAMILY SSF55874 106 238 4.58E-19 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS37275 43c3f7703812388ed9a95a5f43afe0e6 241 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 147 238 4.5E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS37275 43c3f7703812388ed9a95a5f43afe0e6 241 Pfam PF07730 Histidine kinase 62 127 1.2E-7 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS04030 26347dd0ac0c8f14ca5cb697af27739b 140 PANTHER PTHR30007 1 112 1.3E-32 T 23-04-2016 DC74_RS04030 26347dd0ac0c8f14ca5cb697af27739b 140 PANTHER PTHR30007:SF0 1 112 1.3E-32 T 23-04-2016 DC74_RS04030 26347dd0ac0c8f14ca5cb697af27739b 140 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 78 3.1E-26 T 23-04-2016 IPR025161 Putative transposase IS4/IS5 family DC74_RS09915 6f9f92df966dee1547f301391df67369 342 SMART SM00859 4 136 1.2E-45 T 23-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DC74_RS09915 6f9f92df966dee1547f301391df67369 342 Gene3D G3DSA:3.40.50.720 1 154 6.0E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09915 6f9f92df966dee1547f301391df67369 342 SUPERFAMILY SSF51735 3 170 1.72E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09915 6f9f92df966dee1547f301391df67369 342 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 336 37.651 T 23-04-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09915 6f9f92df966dee1547f301391df67369 342 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 23-04-2016 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09915 6f9f92df966dee1547f301391df67369 342 PANTHER PTHR32338:SF8 2 342 3.7E-149 T 23-04-2016 DC74_RS09915 6f9f92df966dee1547f301391df67369 342 PANTHER PTHR32338 2 342 3.7E-149 T 23-04-2016 DC74_RS09915 6f9f92df966dee1547f301391df67369 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 313 1.3E-21 T 23-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09915 6f9f92df966dee1547f301391df67369 342 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 4 342 4.9E-116 T 23-04-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 DC74_RS09915 6f9f92df966dee1547f301391df67369 342 Gene3D G3DSA:3.30.360.10 155 310 1.2E-57 T 23-04-2016 DC74_RS09915 6f9f92df966dee1547f301391df67369 342 SUPERFAMILY SSF55347 146 310 2.94E-47 T 23-04-2016 DC74_RS09915 6f9f92df966dee1547f301391df67369 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 128 2.7E-25 T 23-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DC74_RS23490 6c4efd72e3aad70fa28856cbed918e8e 297 Gene3D G3DSA:3.30.420.40 1 130 4.0E-29 T 23-04-2016 DC74_RS23490 6c4efd72e3aad70fa28856cbed918e8e 297 Pfam PF00480 ROK family 2 287 1.8E-56 T 23-04-2016 IPR000600 ROK family DC74_RS23490 6c4efd72e3aad70fa28856cbed918e8e 297 Gene3D G3DSA:3.30.420.40 131 273 3.8E-46 T 23-04-2016 DC74_RS23490 6c4efd72e3aad70fa28856cbed918e8e 297 PANTHER PTHR18964 204 295 6.4E-94 T 23-04-2016 DC74_RS23490 6c4efd72e3aad70fa28856cbed918e8e 297 PANTHER PTHR18964 1 180 6.4E-94 T 23-04-2016 DC74_RS23490 6c4efd72e3aad70fa28856cbed918e8e 297 SUPERFAMILY SSF53067 2 292 8.5E-50 T 23-04-2016 DC74_RS23490 6c4efd72e3aad70fa28856cbed918e8e 297 PANTHER PTHR18964:SF138 204 295 6.4E-94 T 23-04-2016 DC74_RS23490 6c4efd72e3aad70fa28856cbed918e8e 297 PANTHER PTHR18964:SF138 1 180 6.4E-94 T 23-04-2016 DC74_RS01740 b5f4c403be859598a0cc7666e3e5b5f7 191 SUPERFAMILY SSF48498 74 180 6.52E-18 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS01740 b5f4c403be859598a0cc7666e3e5b5f7 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 59 2.1E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01740 b5f4c403be859598a0cc7666e3e5b5f7 191 Gene3D G3DSA:1.10.10.60 5 53 8.3E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01740 b5f4c403be859598a0cc7666e3e5b5f7 191 SUPERFAMILY SSF46689 6 66 2.21E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS01740 b5f4c403be859598a0cc7666e3e5b5f7 191 Pfam PF16859 Bacterial transcriptional repressor C-terminal 72 175 1.6E-21 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS01740 b5f4c403be859598a0cc7666e3e5b5f7 191 PANTHER PTHR30055:SF67 1 178 1.6E-40 T 23-04-2016 DC74_RS01740 b5f4c403be859598a0cc7666e3e5b5f7 191 Gene3D G3DSA:1.10.357.10 56 181 4.7E-25 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS01740 b5f4c403be859598a0cc7666e3e5b5f7 191 PANTHER PTHR30055 1 178 1.6E-40 T 23-04-2016 DC74_RS01870 613ff7be17946b4b1a59288a6abf60dc 399 SUPERFAMILY SSF51395 31 200 6.28E-91 T 23-04-2016 DC74_RS01870 613ff7be17946b4b1a59288a6abf60dc 399 SUPERFAMILY SSF51395 235 387 6.28E-91 T 23-04-2016 DC74_RS01870 613ff7be17946b4b1a59288a6abf60dc 399 PANTHER PTHR10578:SF79 13 390 2.0E-191 T 23-04-2016 DC74_RS01870 613ff7be17946b4b1a59288a6abf60dc 399 PIRSF PIRSF000138 19 391 5.3E-124 T 23-04-2016 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 DC74_RS01870 613ff7be17946b4b1a59288a6abf60dc 399 PANTHER PTHR10578 13 390 2.0E-191 T 23-04-2016 DC74_RS01870 613ff7be17946b4b1a59288a6abf60dc 399 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 285 291 - T 23-04-2016 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 DC74_RS01870 613ff7be17946b4b1a59288a6abf60dc 399 Pfam PF01070 FMN-dependent dehydrogenase 38 388 6.7E-126 T 23-04-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 DC74_RS01870 613ff7be17946b4b1a59288a6abf60dc 399 Gene3D G3DSA:3.20.20.70 30 389 6.3E-135 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS29485 ee7dae12d98252366e4cb5566d35fdc9 122 PANTHER PTHR33169 11 120 8.0E-28 T 23-04-2016 DC74_RS29485 ee7dae12d98252366e4cb5566d35fdc9 122 PANTHER PTHR33169:SF7 11 120 8.0E-28 T 23-04-2016 DC74_RS29485 ee7dae12d98252366e4cb5566d35fdc9 122 SUPERFAMILY SSF46785 22 112 2.68E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29485 ee7dae12d98252366e4cb5566d35fdc9 122 Gene3D G3DSA:1.10.10.10 22 120 2.7E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29485 ee7dae12d98252366e4cb5566d35fdc9 122 Pfam PF03551 Transcriptional regulator PadR-like family 34 100 1.8E-16 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS21735 5f460a1f1341e6d77ba184079627f04a 501 Pfam PF00155 Aminotransferase class I and II 157 460 2.1E-18 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS21735 5f460a1f1341e6d77ba184079627f04a 501 SUPERFAMILY SSF46785 34 103 2.04E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21735 5f460a1f1341e6d77ba184079627f04a 501 SMART SM00345 40 99 5.1E-9 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS21735 5f460a1f1341e6d77ba184079627f04a 501 PANTHER PTHR11751 124 498 4.3E-91 T 23-04-2016 DC74_RS21735 5f460a1f1341e6d77ba184079627f04a 501 Gene3D G3DSA:1.10.10.10 40 103 1.8E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21735 5f460a1f1341e6d77ba184079627f04a 501 Pfam PF00392 Bacterial regulatory proteins, gntR family 41 99 9.6E-12 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS21735 5f460a1f1341e6d77ba184079627f04a 501 PANTHER PTHR11751:SF10 124 498 4.3E-91 T 23-04-2016 DC74_RS21735 5f460a1f1341e6d77ba184079627f04a 501 SUPERFAMILY SSF53383 127 498 1.48E-81 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS21735 5f460a1f1341e6d77ba184079627f04a 501 Gene3D G3DSA:3.40.640.10 172 388 3.6E-50 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 Gene3D G3DSA:1.10.510.10 97 275 1.1E-39 T 23-04-2016 DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 SUPERFAMILY SSF50998 639 752 9.03E-20 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 Pfam PF00069 Protein kinase domain 17 260 3.6E-40 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 42 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 SUPERFAMILY SSF50998 407 546 4.32E-12 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 Gene3D G3DSA:3.30.200.20 9 90 1.8E-14 T 23-04-2016 DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 SUPERFAMILY SSF56112 11 261 4.65E-60 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 Gene3D G3DSA:2.140.10.10 388 752 5.4E-31 T 23-04-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 SMART SM00564 505 536 140.0 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 SMART SM00564 439 489 4.2 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 SMART SM00564 683 714 0.0091 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 SMART SM00564 642 674 7.6E-4 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 SMART SM00220 14 263 9.6E-37 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 PANTHER PTHR24362 7 260 3.1E-83 T 23-04-2016 DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 Pfam PF13360 PQQ-like domain 620 751 8.7E-15 T 23-04-2016 IPR002372 Pyrrolo-quinoline quinone repeat DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 Pfam PF13360 PQQ-like domain 422 547 1.3E-11 T 23-04-2016 IPR002372 Pyrrolo-quinoline quinone repeat DC74_RS03500 5c34c15d516f5f2c26197190f0106fa9 758 PANTHER PTHR24362:SF247 7 260 3.1E-83 T 23-04-2016 DC74_RS15565 66ce49e928060a7c47965ed5f4b63e3c 345 SUPERFAMILY SSF49879 239 339 1.17E-18 T 23-04-2016 IPR008984 SMAD/FHA domain GO:0005515 DC74_RS15565 66ce49e928060a7c47965ed5f4b63e3c 345 Gene3D G3DSA:2.60.200.20 247 338 1.7E-18 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS15565 66ce49e928060a7c47965ed5f4b63e3c 345 Pfam PF00498 FHA domain 258 335 4.7E-12 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 SMART SM00448 10 124 1.2E-30 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 PANTHER PTHR26402:SF564 10 225 6.3E-100 T 23-04-2016 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 PANTHER PTHR26402 10 225 6.3E-100 T 23-04-2016 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 6.5E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 6.5E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 6.5E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 SMART SM00421 161 218 7.2E-25 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 164 218 4.2E-19 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 Pfam PF00072 Response regulator receiver domain 12 125 2.2E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 SUPERFAMILY SSF46894 150 224 1.43E-22 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 Gene3D G3DSA:3.40.50.2300 8 132 1.1E-37 T 23-04-2016 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 Gene3D G3DSA:1.10.10.10 133 225 2.1E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34965 e24f9542221896d86ab441abbe3b03f5 229 SUPERFAMILY SSF52172 10 141 1.99E-32 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS11075 153ad2cf4d77998b1389b4da78882ab7 600 Gene3D G3DSA:1.50.10.10 216 593 2.1E-83 T 23-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 DC74_RS11075 153ad2cf4d77998b1389b4da78882ab7 600 Pfam PF00723 Glycosyl hydrolases family 15 220 552 3.4E-70 T 23-04-2016 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: REACT_474 DC74_RS11075 153ad2cf4d77998b1389b4da78882ab7 600 PANTHER PTHR31616:SF0 6 592 2.2E-207 T 23-04-2016 DC74_RS11075 153ad2cf4d77998b1389b4da78882ab7 600 PANTHER PTHR31616 6 592 2.2E-207 T 23-04-2016 DC74_RS11075 153ad2cf4d77998b1389b4da78882ab7 600 SUPERFAMILY SSF48208 194 593 3.06E-108 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 DC74_RS21975 3aee762e5bd78adb865e89677f1d2fba 278 Pfam PF13649 Methyltransferase domain 60 158 1.0E-9 T 23-04-2016 DC74_RS21975 3aee762e5bd78adb865e89677f1d2fba 278 PANTHER PTHR10108:SF868 36 187 5.0E-24 T 23-04-2016 DC74_RS21975 3aee762e5bd78adb865e89677f1d2fba 278 PANTHER PTHR10108:SF868 204 269 5.0E-24 T 23-04-2016 DC74_RS21975 3aee762e5bd78adb865e89677f1d2fba 278 PANTHER PTHR10108 36 187 5.0E-24 T 23-04-2016 DC74_RS21975 3aee762e5bd78adb865e89677f1d2fba 278 PANTHER PTHR10108 204 269 5.0E-24 T 23-04-2016 DC74_RS21975 3aee762e5bd78adb865e89677f1d2fba 278 Gene3D G3DSA:3.40.50.150 55 236 1.3E-21 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS21975 3aee762e5bd78adb865e89677f1d2fba 278 SUPERFAMILY SSF53335 28 245 3.75E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS09320 3b018a1e6f3e623cc01772d09386be80 489 PANTHER PTHR11785 1 9 3.0E-266 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS09320 3b018a1e6f3e623cc01772d09386be80 489 PANTHER PTHR11785 25 488 3.0E-266 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS09320 3b018a1e6f3e623cc01772d09386be80 489 Pfam PF13520 Amino acid permease 52 452 1.3E-55 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS09320 3b018a1e6f3e623cc01772d09386be80 489 PIRSF PIRSF006060 35 488 1.5E-93 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS09320 3b018a1e6f3e623cc01772d09386be80 489 PANTHER PTHR11785:SF328 25 488 3.0E-266 T 23-04-2016 DC74_RS09320 3b018a1e6f3e623cc01772d09386be80 489 TIGRFAM TIGR00909 2A0306: amino acid transporter 47 477 2.7E-177 T 23-04-2016 IPR004758 Amino acid transporter DC74_RS09320 3b018a1e6f3e623cc01772d09386be80 489 PANTHER PTHR11785:SF328 1 9 3.0E-266 T 23-04-2016 DC74_RS16820 69a024c470009eba781050cb998f9b8e 232 PANTHER PTHR18901:SF40 18 231 4.1E-70 T 23-04-2016 DC74_RS16820 69a024c470009eba781050cb998f9b8e 232 Gene3D G3DSA:3.40.50.1000 84 225 2.2E-18 T 23-04-2016 IPR023214 HAD-like domain DC74_RS16820 69a024c470009eba781050cb998f9b8e 232 SUPERFAMILY SSF56784 15 225 4.51E-31 T 23-04-2016 IPR023214 HAD-like domain DC74_RS16820 69a024c470009eba781050cb998f9b8e 232 PANTHER PTHR18901 18 231 4.1E-70 T 23-04-2016 DC74_RS16820 69a024c470009eba781050cb998f9b8e 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 20 197 3.7E-11 T 23-04-2016 IPR023214 HAD-like domain DC74_RS01135 f640db38c0561a62cb5a3cdaa47c2dab 373 Pfam PF01494 FAD binding domain 3 347 1.6E-18 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS01135 f640db38c0561a62cb5a3cdaa47c2dab 373 Gene3D G3DSA:3.50.50.60 2 173 1.5E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS01135 f640db38c0561a62cb5a3cdaa47c2dab 373 Gene3D G3DSA:3.50.50.60 276 351 1.5E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS01135 f640db38c0561a62cb5a3cdaa47c2dab 373 PANTHER PTHR13789:SF174 1 353 5.1E-117 T 23-04-2016 DC74_RS01135 f640db38c0561a62cb5a3cdaa47c2dab 373 SUPERFAMILY SSF51905 3 168 9.55E-44 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS01135 f640db38c0561a62cb5a3cdaa47c2dab 373 SUPERFAMILY SSF51905 275 351 9.55E-44 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS01135 f640db38c0561a62cb5a3cdaa47c2dab 373 PANTHER PTHR13789 1 353 5.1E-117 T 23-04-2016 DC74_RS01135 f640db38c0561a62cb5a3cdaa47c2dab 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.1E-13 T 23-04-2016 DC74_RS01135 f640db38c0561a62cb5a3cdaa47c2dab 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 1.1E-13 T 23-04-2016 DC74_RS01135 f640db38c0561a62cb5a3cdaa47c2dab 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.1E-13 T 23-04-2016 DC74_RS28440 7a7cce3847886709c2fc978da641d556 97 Pfam PF04456 Protein of unknown function (DUF503) 3 89 7.1E-32 T 23-04-2016 IPR007546 Protein of unknown function DUF503 DC74_RS28440 7a7cce3847886709c2fc978da641d556 97 Gene3D G3DSA:3.30.70.1120 1 96 1.2E-36 T 23-04-2016 IPR007546 Protein of unknown function DUF503 DC74_RS28440 7a7cce3847886709c2fc978da641d556 97 SUPERFAMILY SSF103007 1 93 9.15E-31 T 23-04-2016 IPR007546 Protein of unknown function DUF503 DC74_RS28440 7a7cce3847886709c2fc978da641d556 97 PANTHER PTHR36441 2 97 1.5E-32 T 23-04-2016 DC74_RS13060 76d6780f761f02adbb57a86f9e0b3e9d 207 Gene3D G3DSA:1.10.10.10 7 72 2.8E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13060 76d6780f761f02adbb57a86f9e0b3e9d 207 Pfam PF07729 FCD domain 82 199 1.4E-18 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS13060 76d6780f761f02adbb57a86f9e0b3e9d 207 SUPERFAMILY SSF46785 8 97 8.75E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13060 76d6780f761f02adbb57a86f9e0b3e9d 207 SMART SM00895 81 202 6.0E-14 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS13060 76d6780f761f02adbb57a86f9e0b3e9d 207 SUPERFAMILY SSF48008 77 199 4.97E-22 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS13060 76d6780f761f02adbb57a86f9e0b3e9d 207 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 1.8E-17 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS13060 76d6780f761f02adbb57a86f9e0b3e9d 207 PANTHER PTHR11751 8 97 9.5E-26 T 23-04-2016 DC74_RS13060 76d6780f761f02adbb57a86f9e0b3e9d 207 SMART SM00345 13 71 2.0E-15 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS13060 76d6780f761f02adbb57a86f9e0b3e9d 207 Gene3D G3DSA:1.20.120.530 74 202 1.5E-23 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS29845 1bdad77c1d45d6b44a61f61f165f8977 254 SUPERFAMILY SSF102462 157 245 2.79E-18 T 23-04-2016 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 DC74_RS29845 1bdad77c1d45d6b44a61f61f165f8977 254 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 159 244 3.4E-6 T 23-04-2016 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 DC74_RS29845 1bdad77c1d45d6b44a61f61f165f8977 254 Gene3D G3DSA:3.40.1490.10 157 244 5.2E-15 T 23-04-2016 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 DC74_RS07910 6493d36ba59b0a844aedda68809607fd 236 PANTHER PTHR23026 20 234 9.4E-29 T 23-04-2016 DC74_RS07910 6493d36ba59b0a844aedda68809607fd 236 Gene3D G3DSA:3.40.109.10 138 234 7.2E-37 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS07910 6493d36ba59b0a844aedda68809607fd 236 Gene3D G3DSA:3.40.109.10 18 105 7.2E-37 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS07910 6493d36ba59b0a844aedda68809607fd 236 Pfam PF00881 Nitroreductase family 24 211 1.6E-26 T 23-04-2016 IPR029479 Nitroreductase DC74_RS07910 6493d36ba59b0a844aedda68809607fd 236 PANTHER PTHR23026:SF90 20 234 9.4E-29 T 23-04-2016 DC74_RS07910 6493d36ba59b0a844aedda68809607fd 236 SUPERFAMILY SSF55469 20 234 4.58E-35 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS27110 40c5f2d88f9ed18387525035b688daff 349 PANTHER PTHR30137:SF8 1 348 1.0E-98 T 23-04-2016 DC74_RS27110 40c5f2d88f9ed18387525035b688daff 349 Pfam PF00296 Luciferase-like monooxygenase 1 318 5.3E-54 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS27110 40c5f2d88f9ed18387525035b688daff 349 SUPERFAMILY SSF51679 1 348 9.16E-69 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS27110 40c5f2d88f9ed18387525035b688daff 349 Gene3D G3DSA:3.20.20.30 1 348 1.3E-89 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS27110 40c5f2d88f9ed18387525035b688daff 349 PANTHER PTHR30137 1 348 1.0E-98 T 23-04-2016 DC74_RS04970 f521fd12036d832db0023e406a7d7323 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 247 3.2E-31 T 23-04-2016 DC74_RS04970 f521fd12036d832db0023e406a7d7323 252 SUPERFAMILY SSF51735 16 250 5.52E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04970 f521fd12036d832db0023e406a7d7323 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 19 192 0.0092 T 23-04-2016 DC74_RS04970 f521fd12036d832db0023e406a7d7323 252 Gene3D G3DSA:3.40.50.720 16 249 1.6E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04970 f521fd12036d832db0023e406a7d7323 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.2E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04970 f521fd12036d832db0023e406a7d7323 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 3.2E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04970 f521fd12036d832db0023e406a7d7323 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 3.2E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04970 f521fd12036d832db0023e406a7d7323 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.2E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04970 f521fd12036d832db0023e406a7d7323 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.2E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS39600 a9c5b6fca358571a7b92e739672e3abe 212 SUPERFAMILY SSF54593 2 101 7.43E-13 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS39600 a9c5b6fca358571a7b92e739672e3abe 212 Gene3D G3DSA:3.10.180.10 2 101 1.2E-13 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS39600 a9c5b6fca358571a7b92e739672e3abe 212 PANTHER PTHR36503:SF1 1 115 2.1E-30 T 23-04-2016 DC74_RS39600 a9c5b6fca358571a7b92e739672e3abe 212 PANTHER PTHR36503 1 115 2.1E-30 T 23-04-2016 DC74_RS39600 a9c5b6fca358571a7b92e739672e3abe 212 Gene3D G3DSA:3.10.180.10 120 203 8.0E-6 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS21370 227c627b838b70f1b31b790578104943 388 PIRSF PIRSF000429 10 378 2.4E-22 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS21370 227c627b838b70f1b31b790578104943 388 SUPERFAMILY SSF53901 12 237 8.35E-25 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS21370 227c627b838b70f1b31b790578104943 388 PANTHER PTHR18919 8 388 7.0E-119 T 23-04-2016 DC74_RS21370 227c627b838b70f1b31b790578104943 388 SUPERFAMILY SSF53901 266 368 5.76E-14 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS21370 227c627b838b70f1b31b790578104943 388 Gene3D G3DSA:3.40.47.10 207 234 1.2E-13 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS21370 227c627b838b70f1b31b790578104943 388 Gene3D G3DSA:3.40.47.10 17 119 1.2E-13 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS21370 227c627b838b70f1b31b790578104943 388 Pfam PF00108 Thiolase, N-terminal domain 30 231 1.5E-6 T 23-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 DC74_RS21370 227c627b838b70f1b31b790578104943 388 PANTHER PTHR18919:SF108 8 388 7.0E-119 T 23-04-2016 DC74_RS18020 31cc11c2533c71654e4cc14a7c6c7e2d 165 Gene3D G3DSA:1.10.10.10 4 155 1.9E-36 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18020 31cc11c2533c71654e4cc14a7c6c7e2d 165 PANTHER PTHR33164:SF1 8 165 3.0E-41 T 23-04-2016 DC74_RS18020 31cc11c2533c71654e4cc14a7c6c7e2d 165 PANTHER PTHR33164 8 165 3.0E-41 T 23-04-2016 DC74_RS18020 31cc11c2533c71654e4cc14a7c6c7e2d 165 SMART SM00347 37 140 1.3E-17 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS18020 31cc11c2533c71654e4cc14a7c6c7e2d 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 3.4E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS18020 31cc11c2533c71654e4cc14a7c6c7e2d 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 3.4E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS18020 31cc11c2533c71654e4cc14a7c6c7e2d 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 3.4E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS18020 31cc11c2533c71654e4cc14a7c6c7e2d 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 3.4E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS18020 31cc11c2533c71654e4cc14a7c6c7e2d 165 Pfam PF12802 MarR family 43 103 4.5E-13 T 23-04-2016 DC74_RS18020 31cc11c2533c71654e4cc14a7c6c7e2d 165 SUPERFAMILY SSF46785 6 154 5.77E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 Gene3D G3DSA:2.60.40.420 423 545 8.3E-41 T 23-04-2016 IPR008972 Cupredoxin DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 Gene3D G3DSA:2.60.40.420 270 404 2.2E-38 T 23-04-2016 IPR008972 Cupredoxin DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 Gene3D G3DSA:2.60.40.420 188 226 2.2E-38 T 23-04-2016 IPR008972 Cupredoxin DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 Pfam PF07731 Multicopper oxidase 437 542 4.8E-25 T 23-04-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 ProSitePatterns PS00079 Multicopper oxidases signature 1. 523 543 - T 23-04-2016 IPR033138 Multicopper oxidases, conserved site DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 SUPERFAMILY SSF49503 421 543 1.38E-32 T 23-04-2016 IPR008972 Cupredoxin DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 PANTHER PTHR11709 292 540 2.0E-87 T 23-04-2016 DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 PANTHER PTHR11709 64 222 2.0E-87 T 23-04-2016 DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 SUPERFAMILY SSF49503 185 225 7.72E-27 T 23-04-2016 IPR008972 Cupredoxin DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 SUPERFAMILY SSF49503 291 400 7.72E-27 T 23-04-2016 IPR008972 Cupredoxin DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 ProSitePatterns PS00080 Multicopper oxidases signature 2. 528 539 - T 23-04-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 Pfam PF00394 Multicopper oxidase 276 377 1.1E-17 T 23-04-2016 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 SUPERFAMILY SSF49503 64 200 4.23E-37 T 23-04-2016 IPR008972 Cupredoxin DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 PANTHER PTHR11709:SF33 292 540 2.0E-87 T 23-04-2016 DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 PANTHER PTHR11709:SF33 64 222 2.0E-87 T 23-04-2016 DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 Gene3D G3DSA:2.60.40.420 51 181 2.5E-35 T 23-04-2016 IPR008972 Cupredoxin DC74_RS37995 bab6f1a139ea6cc1b67bbb0280f52a05 547 Pfam PF07732 Multicopper oxidase 77 183 8.5E-32 T 23-04-2016 IPR011707 Multicopper oxidase, type 3 GO:0005507 DC74_RS02885 0371ce41a5ffe9c2d321500e8b1f4250 387 SUPERFAMILY SSF53756 8 384 1.83E-90 T 23-04-2016 DC74_RS02885 0371ce41a5ffe9c2d321500e8b1f4250 387 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 9 385 30.788 T 23-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS02885 0371ce41a5ffe9c2d321500e8b1f4250 387 PANTHER PTHR21015:SF22 2 385 1.3E-89 T 23-04-2016 DC74_RS02885 0371ce41a5ffe9c2d321500e8b1f4250 387 Gene3D G3DSA:3.40.50.2000 280 363 7.3E-9 T 23-04-2016 DC74_RS02885 0371ce41a5ffe9c2d321500e8b1f4250 387 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 10 158 2.3E-28 T 23-04-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS02885 0371ce41a5ffe9c2d321500e8b1f4250 387 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 210 377 5.9E-34 T 23-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS02885 0371ce41a5ffe9c2d321500e8b1f4250 387 PANTHER PTHR21015 2 385 1.3E-89 T 23-04-2016 DC74_RS02885 0371ce41a5ffe9c2d321500e8b1f4250 387 Gene3D G3DSA:3.40.50.2000 8 223 1.2E-55 T 23-04-2016 DC74_RS08235 4325dd5d3a62ab42707823218ec71b7f 141 SUPERFAMILY SSF103196 15 140 1.4E-35 T 23-04-2016 DC74_RS08235 4325dd5d3a62ab42707823218ec71b7f 141 Gene3D G3DSA:3.30.450.30 18 138 1.6E-26 T 23-04-2016 DC74_RS08235 4325dd5d3a62ab42707823218ec71b7f 141 PANTHER PTHR36222 9 140 3.2E-50 T 23-04-2016 DC74_RS08235 4325dd5d3a62ab42707823218ec71b7f 141 Pfam PF03259 Roadblock/LC7 domain 20 111 2.5E-25 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS08235 4325dd5d3a62ab42707823218ec71b7f 141 SMART SM00960 21 111 2.2E-28 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS19215 d2578db37562a56ed6f841ae6356f398 174 PANTHER PTHR23091 10 173 1.7E-29 T 23-04-2016 DC74_RS19215 d2578db37562a56ed6f841ae6356f398 174 Pfam PF00583 Acetyltransferase (GNAT) family 69 147 5.5E-11 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS19215 d2578db37562a56ed6f841ae6356f398 174 Gene3D G3DSA:3.40.630.30 12 173 6.5E-31 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS19215 d2578db37562a56ed6f841ae6356f398 174 PANTHER PTHR23091:SF264 10 173 1.7E-29 T 23-04-2016 DC74_RS19215 d2578db37562a56ed6f841ae6356f398 174 SUPERFAMILY SSF55729 13 173 8.95E-27 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS11465 a03b0d98ea7636569aca15537680bf1a 259 PANTHER PTHR11941:SF28 9 252 1.7E-63 T 23-04-2016 DC74_RS11465 a03b0d98ea7636569aca15537680bf1a 259 PANTHER PTHR11941 9 252 1.7E-63 T 23-04-2016 DC74_RS11465 a03b0d98ea7636569aca15537680bf1a 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 115 135 - T 23-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 DC74_RS11465 a03b0d98ea7636569aca15537680bf1a 259 SUPERFAMILY SSF52096 8 251 5.16E-61 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS11465 a03b0d98ea7636569aca15537680bf1a 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 246 1.7E-36 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS11465 a03b0d98ea7636569aca15537680bf1a 259 Gene3D G3DSA:3.90.226.10 8 252 3.3E-58 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS23105 155e34834a34ed74ca80e745c42c57a7 340 Pfam PF06089 L-asparaginase II 34 337 2.7E-111 T 23-04-2016 IPR010349 L-asparaginase II DC74_RS23105 155e34834a34ed74ca80e745c42c57a7 340 PANTHER PTHR42110 20 340 5.7E-76 T 23-04-2016 DC74_RS23105 155e34834a34ed74ca80e745c42c57a7 340 PANTHER PTHR42110:SF1 20 340 5.7E-76 T 23-04-2016 DC74_RS22525 0ae8d49428d5bcedd26e05e0e6faa795 387 Gene3D G3DSA:3.30.565.10 292 385 2.1E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS22525 0ae8d49428d5bcedd26e05e0e6faa795 387 PANTHER PTHR24421 27 385 1.6E-95 T 23-04-2016 DC74_RS22525 0ae8d49428d5bcedd26e05e0e6faa795 387 SUPERFAMILY SSF55874 259 383 1.92E-17 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS22525 0ae8d49428d5bcedd26e05e0e6faa795 387 Pfam PF07730 Histidine kinase 176 241 5.9E-21 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS22525 0ae8d49428d5bcedd26e05e0e6faa795 387 PANTHER PTHR24421:SF26 27 385 1.6E-95 T 23-04-2016 DC74_RS38115 1b2a467017bd37a45c318746f4c8ff41 185 SUPERFAMILY SSF52499 2 181 2.09E-48 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS38115 1b2a467017bd37a45c318746f4c8ff41 185 Gene3D G3DSA:3.40.50.850 1 181 3.0E-49 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS38115 1b2a467017bd37a45c318746f4c8ff41 185 PANTHER PTHR11080 3 181 1.0E-34 T 23-04-2016 DC74_RS38115 1b2a467017bd37a45c318746f4c8ff41 185 Pfam PF00857 Isochorismatase family 4 176 9.4E-37 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS01275 869576376d750c1c56e320e7620af89d 400 SUPERFAMILY SSF53756 1 377 2.09E-47 T 23-04-2016 DC74_RS01275 869576376d750c1c56e320e7620af89d 400 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 210 356 5.1E-14 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS01275 869576376d750c1c56e320e7620af89d 400 Gene3D G3DSA:3.40.50.2000 212 364 2.3E-22 T 23-04-2016 DC74_RS01275 869576376d750c1c56e320e7620af89d 400 Gene3D G3DSA:3.40.50.2000 28 135 6.1E-8 T 23-04-2016 DC74_RS01275 869576376d750c1c56e320e7620af89d 400 PANTHER PTHR11926 213 369 3.5E-18 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS26835 1f7c5b647413da48ffabb3c5be255582 121 SMART SM00448 3 115 2.0E-30 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS26835 1f7c5b647413da48ffabb3c5be255582 121 Pfam PF00072 Response regulator receiver domain 5 114 6.3E-24 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS26835 1f7c5b647413da48ffabb3c5be255582 121 Gene3D G3DSA:3.40.50.2300 4 120 3.5E-35 T 23-04-2016 DC74_RS26835 1f7c5b647413da48ffabb3c5be255582 121 PANTHER PTHR26402 3 120 5.2E-39 T 23-04-2016 DC74_RS26835 1f7c5b647413da48ffabb3c5be255582 121 PANTHER PTHR26402:SF497 3 120 5.2E-39 T 23-04-2016 DC74_RS26835 1f7c5b647413da48ffabb3c5be255582 121 SUPERFAMILY SSF52172 4 120 3.7E-33 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS14775 ee46a49f1d80e36fe19892b1d48714ec 552 PANTHER PTHR22642:SF2 1 548 2.8E-121 T 23-04-2016 DC74_RS14775 ee46a49f1d80e36fe19892b1d48714ec 552 SUPERFAMILY SSF51338 11 70 2.16E-14 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS14775 ee46a49f1d80e36fe19892b1d48714ec 552 SUPERFAMILY SSF51338 506 548 2.16E-14 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS14775 ee46a49f1d80e36fe19892b1d48714ec 552 Pfam PF07969 Amidohydrolase family 58 545 8.0E-82 T 23-04-2016 IPR013108 Amidohydrolase 3 DC74_RS14775 ee46a49f1d80e36fe19892b1d48714ec 552 Gene3D G3DSA:2.30.40.10 5 79 4.1E-16 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS14775 ee46a49f1d80e36fe19892b1d48714ec 552 SUPERFAMILY SSF51556 218 507 3.02E-33 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS14775 ee46a49f1d80e36fe19892b1d48714ec 552 SUPERFAMILY SSF51556 69 109 3.02E-33 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS14775 ee46a49f1d80e36fe19892b1d48714ec 552 PANTHER PTHR22642 1 548 2.8E-121 T 23-04-2016 DC74_RS14775 ee46a49f1d80e36fe19892b1d48714ec 552 Gene3D G3DSA:3.20.20.140 80 91 2.7E-34 T 23-04-2016 DC74_RS14775 ee46a49f1d80e36fe19892b1d48714ec 552 Gene3D G3DSA:3.20.20.140 222 501 2.7E-34 T 23-04-2016 DC74_RS01370 d73cbb5f3442405cff50509402880645 300 PANTHER PTHR23200 6 273 5.5E-105 T 23-04-2016 DC74_RS01370 d73cbb5f3442405cff50509402880645 300 Pfam PF00753 Metallo-beta-lactamase superfamily 60 273 7.6E-31 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS01370 d73cbb5f3442405cff50509402880645 300 SUPERFAMILY SSF56281 41 289 2.23E-40 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS01370 d73cbb5f3442405cff50509402880645 300 SMART SM00849 59 273 2.3E-22 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS01370 d73cbb5f3442405cff50509402880645 300 PANTHER PTHR23200:SF43 6 273 5.5E-105 T 23-04-2016 DC74_RS01370 d73cbb5f3442405cff50509402880645 300 Gene3D G3DSA:3.60.15.10 19 289 7.5E-53 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS10710 6505e99cd2582adbd3f95e90099fcd85 313 Pfam PF03253 Urea transporter 12 301 7.9E-82 T 23-04-2016 IPR004937 Urea transporter GO:0015204|GO:0016021|GO:0071918 Reactome: REACT_15518|Reactome: REACT_20679 DC74_RS10710 6505e99cd2582adbd3f95e90099fcd85 313 PANTHER PTHR10464 8 301 8.6E-52 T 23-04-2016 IPR004937 Urea transporter GO:0015204|GO:0016021|GO:0071918 Reactome: REACT_15518|Reactome: REACT_20679 DC74_RS10710 6505e99cd2582adbd3f95e90099fcd85 313 Gene3D G3DSA:1.10.3430.10 8 305 3.3E-75 T 23-04-2016 IPR029020 Ammonium/urea transporter DC74_RS10710 6505e99cd2582adbd3f95e90099fcd85 313 PIRSF PIRSF016502 3 310 1.7E-64 T 23-04-2016 IPR004937 Urea transporter GO:0015204|GO:0016021|GO:0071918 Reactome: REACT_15518|Reactome: REACT_20679 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 333 81.661 T 23-04-2016 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PANTHER PTHR11405:SF44 1 277 1.5E-184 T 23-04-2016 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PANTHER PTHR11405:SF44 297 333 1.5E-184 T 23-04-2016 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 332 1.1E-121 T 23-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 5.4E-25 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 5.4E-25 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 297 320 5.4E-25 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 277 5.4E-25 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 Gene3D G3DSA:3.40.50.1370 5 144 1.3E-55 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 SUPERFAMILY SSF53671 4 332 1.96E-93 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 Gene3D G3DSA:3.40.50.1370 145 319 6.4E-66 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 3.7E-47 T 23-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 159 330 1.2E-49 T 23-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PANTHER PTHR11405 1 277 1.5E-184 T 23-04-2016 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PANTHER PTHR11405 297 333 1.5E-184 T 23-04-2016 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 1.6E-31 T 23-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 1.6E-31 T 23-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 230 240 1.6E-31 T 23-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 1.6E-31 T 23-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 DC74_RS29345 953a2dda0345729ff56561854af61f3c 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 311 322 1.6E-31 T 23-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 DC74_RS37095 42dc52a4b883689b3f6b38dafd13a2fa 432 PANTHER PTHR31299 13 432 1.4E-45 T 23-04-2016 DC74_RS37095 42dc52a4b883689b3f6b38dafd13a2fa 432 Gene3D G3DSA:3.40.1660.10 7 71 1.2E-40 T 23-04-2016 DC74_RS37095 42dc52a4b883689b3f6b38dafd13a2fa 432 Gene3D G3DSA:3.40.1660.10 288 425 1.2E-40 T 23-04-2016 DC74_RS37095 42dc52a4b883689b3f6b38dafd13a2fa 432 PANTHER PTHR31299:SF0 13 432 1.4E-45 T 23-04-2016 DC74_RS37095 42dc52a4b883689b3f6b38dafd13a2fa 432 SUPERFAMILY SSF159501 7 426 4.71E-76 T 23-04-2016 DC74_RS37095 42dc52a4b883689b3f6b38dafd13a2fa 432 PIRSF PIRSF000880 12 430 3.1E-94 T 23-04-2016 IPR016273 Erythromycin esterase, proteobacteria KEGG: 00051+3.1.1.-|KEGG: 00053+3.1.1.-|KEGG: 00363+3.1.1.-|KEGG: 00365+3.1.1.-|KEGG: 00534+3.1.1.-|KEGG: 00564+3.1.1.-|KEGG: 00623+3.1.1.-|KEGG: 00640+3.1.1.-|KEGG: 00830+3.1.1.-|KEGG: 00900+3.1.1.-|KEGG: 00940+3.1.1.-|KEGG: 00960+3.1.1.- DC74_RS37095 42dc52a4b883689b3f6b38dafd13a2fa 432 Pfam PF05139 Erythromycin esterase 70 422 8.4E-51 T 23-04-2016 IPR007815 Erythromycin esterase GO:0046677 DC74_RS37095 42dc52a4b883689b3f6b38dafd13a2fa 432 Gene3D G3DSA:3.30.1870.10 73 140 7.3E-5 T 23-04-2016 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:1.10.10.10 144 201 7.9E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF46894 128 202 2.79E-20 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 194 3.5E-18 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00448 2 115 4.9E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 PANTHER PTHR26402:SF563 2 202 8.6E-97 T 23-04-2016 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 Gene3D G3DSA:3.40.50.2300 1 143 5.2E-34 T 23-04-2016 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 PANTHER PTHR26402 2 202 8.6E-97 T 23-04-2016 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 SMART SM00421 139 196 1.2E-22 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 3.21E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 3.21E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 3.21E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS18450 5e671cd532bc3faaca485869e5a8630e 203 SUPERFAMILY SSF52172 1 127 1.37E-29 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS19970 1fe16a21c2be21c5c6dba423cf08d943 528 SUPERFAMILY SSF50370 403 527 2.97E-25 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS19970 1fe16a21c2be21c5c6dba423cf08d943 528 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 99 364 5.7E-14 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS19970 1fe16a21c2be21c5c6dba423cf08d943 528 SMART SM00458 403 528 5.6E-10 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS19970 1fe16a21c2be21c5c6dba423cf08d943 528 Gene3D G3DSA:2.80.10.50 408 527 9.6E-23 T 23-04-2016 DC74_RS19970 1fe16a21c2be21c5c6dba423cf08d943 528 Gene3D G3DSA:3.40.50.1110 94 373 2.9E-38 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS19970 1fe16a21c2be21c5c6dba423cf08d943 528 SUPERFAMILY SSF52266 95 375 4.0E-49 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS19970 1fe16a21c2be21c5c6dba423cf08d943 528 Pfam PF00652 Ricin-type beta-trefoil lectin domain 406 527 1.4E-17 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS30745 1d27dc0fe9c1493273a33b1dfe74298e 145 SUPERFAMILY SSF55874 52 140 3.73E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS30745 1d27dc0fe9c1493273a33b1dfe74298e 145 Pfam PF13581 Histidine kinase-like ATPase domain 36 134 1.1E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS30745 1d27dc0fe9c1493273a33b1dfe74298e 145 Gene3D G3DSA:3.30.565.10 54 141 2.0E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS19175 371e1f23d826243073e84d6fe3e26426 600 Pfam PF06259 Alpha/beta hydrolase 359 532 2.0E-32 T 23-04-2016 IPR010427 Protein of unknown function DUF1023 DC74_RS25060 3ebc2ebc28250bc41b8593da47483f82 271 SUPERFAMILY SSF53167 16 270 1.02E-77 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS25060 3ebc2ebc28250bc41b8593da47483f82 271 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 32 267 1.5E-75 T 23-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 DC74_RS25060 3ebc2ebc28250bc41b8593da47483f82 271 PIRSF PIRSF000477 4 271 1.3E-88 T 23-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 DC74_RS25060 3ebc2ebc28250bc41b8593da47483f82 271 PANTHER PTHR11904:SF9 6 271 1.9E-96 T 23-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 DC74_RS25060 3ebc2ebc28250bc41b8593da47483f82 271 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 32 268 1.8E-99 T 23-04-2016 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 DC74_RS25060 3ebc2ebc28250bc41b8593da47483f82 271 Gene3D G3DSA:3.40.50.1580 14 270 1.2E-88 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS25060 3ebc2ebc28250bc41b8593da47483f82 271 PANTHER PTHR11904 6 271 1.9E-96 T 23-04-2016 IPR001369 PNP/MTAP phosphorylase DC74_RS25060 3ebc2ebc28250bc41b8593da47483f82 271 Pfam PF01048 Phosphorylase superfamily 33 268 1.0E-40 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS32710 db1b6b6148baae44165ca11caac70e72 260 Gene3D G3DSA:3.75.10.10 1 256 2.0E-60 T 23-04-2016 DC74_RS32710 db1b6b6148baae44165ca11caac70e72 260 SUPERFAMILY SSF55909 2 257 1.61E-51 T 23-04-2016 DC74_RS32710 db1b6b6148baae44165ca11caac70e72 260 PANTHER PTHR12737 1 257 2.0E-99 T 23-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS32710 db1b6b6148baae44165ca11caac70e72 260 PANTHER PTHR12737:SF20 1 257 2.0E-99 T 23-04-2016 DC74_RS32710 db1b6b6148baae44165ca11caac70e72 260 Pfam PF02274 Amidinotransferase 28 256 1.2E-16 T 23-04-2016 DC74_RS19240 b9f365d79cabe71784410af3b10c7f81 85 Gene3D G3DSA:1.10.1220.10 4 50 5.2E-5 T 23-04-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DC74_RS19240 b9f365d79cabe71784410af3b10c7f81 85 SUPERFAMILY SSF47598 1 46 1.78E-6 T 23-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 DC74_RS21300 e6d034123e714ccae35f5b7faf484147 214 Pfam PF13581 Histidine kinase-like ATPase domain 7 130 1.2E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS12180 7687baef7a25d9912320ed04bfb395d3 1022 Pfam PF12905 Endo-alpha-N-acetylgalactosaminidase 276 664 3.0E-166 T 23-04-2016 IPR025706 Endo-alpha-N-acetylgalactosaminidase GO:0033926 DC74_RS36855 6937fa507f9ed89f98f06cd9e78cd30a 234 Gene3D G3DSA:3.20.180.10 135 225 8.4E-7 T 23-04-2016 IPR019595 Domain of unknown function DUF2470 DC74_RS36855 6937fa507f9ed89f98f06cd9e78cd30a 234 SUPERFAMILY SSF50475 98 224 3.92E-10 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS36855 6937fa507f9ed89f98f06cd9e78cd30a 234 Pfam PF10615 Protein of unknown function (DUF2470) 140 218 1.6E-6 T 23-04-2016 IPR019595 Domain of unknown function DUF2470 DC74_RS23810 f613823df6a105b364fa615e31a0f275 137 SUPERFAMILY SSF50475 12 112 1.46E-14 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS23810 f613823df6a105b364fa615e31a0f275 137 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 8 132 8.7E-35 T 23-04-2016 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative DC74_RS23810 f613823df6a105b364fa615e31a0f275 137 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 88 1.8E-4 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS23810 f613823df6a105b364fa615e31a0f275 137 Gene3D G3DSA:2.30.110.10 12 105 1.3E-10 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS15375 f6e48d1dd02e36c8bef7780f8589a800 162 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 1.9E-72 T 23-04-2016 IPR011860 Ribose 5-phosphate isomerase GO:0004751 DC74_RS15375 f6e48d1dd02e36c8bef7780f8589a800 162 Pfam PF02502 Ribose/Galactose Isomerase 3 142 7.3E-46 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 DC74_RS15375 f6e48d1dd02e36c8bef7780f8589a800 162 PANTHER PTHR30345 1 155 6.3E-64 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 DC74_RS15375 f6e48d1dd02e36c8bef7780f8589a800 162 SUPERFAMILY SSF89623 1 152 6.28E-53 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 DC74_RS15375 f6e48d1dd02e36c8bef7780f8589a800 162 PIRSF PIRSF005384 1 149 2.7E-50 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 DC74_RS15375 f6e48d1dd02e36c8bef7780f8589a800 162 Gene3D G3DSA:3.40.1400.10 1 149 5.1E-55 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 DC74_RS15375 f6e48d1dd02e36c8bef7780f8589a800 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 5.8E-53 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 SUPERFAMILY SSF56281 16 571 1.34E-113 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 Pfam PF00753 Metallo-beta-lactamase superfamily 117 368 2.9E-27 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 PANTHER PTHR11935:SF93 294 509 2.6E-138 T 23-04-2016 DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 PANTHER PTHR11935:SF93 65 213 2.6E-138 T 23-04-2016 DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 SUPERFAMILY SSF55718 579 716 1.53E-13 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 PANTHER PTHR11935 294 509 2.6E-138 T 23-04-2016 DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 SMART SM00849 120 368 4.4E-15 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 Pfam PF14863 Alkyl sulfatase dimerisation 417 568 9.6E-56 T 23-04-2016 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 Pfam PF14864 Alkyl sulfatase C-terminal 577 715 2.8E-22 T 23-04-2016 IPR029229 Alkyl sulfatase, C-terminal DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 PANTHER PTHR11935:SF93 237 272 2.6E-138 T 23-04-2016 DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 Gene3D G3DSA:3.60.15.10 274 409 1.5E-28 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 Gene3D G3DSA:3.60.15.10 111 211 1.5E-28 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 PANTHER PTHR11935 237 272 2.6E-138 T 23-04-2016 DC74_RS14790 cba1c8a74e212135f35c3b211ca6b722 719 PANTHER PTHR11935 65 213 2.6E-138 T 23-04-2016 DC74_RS17840 546b54467bbc072437eb40301469ca20 440 Pfam PF03454 MoeA C-terminal region (domain IV) 377 437 5.8E-13 T 23-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS17840 546b54467bbc072437eb40301469ca20 440 Pfam PF03453 MoeA N-terminal region (domain I and II) 16 198 4.9E-35 T 23-04-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS17840 546b54467bbc072437eb40301469ca20 440 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 208 350 4.7E-30 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS17840 546b54467bbc072437eb40301469ca20 440 Gene3D G3DSA:3.40.980.10 194 367 3.5E-60 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS17840 546b54467bbc072437eb40301469ca20 440 SMART SM00852 211 354 3.6E-40 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS17840 546b54467bbc072437eb40301469ca20 440 Pfam PF00994 Probable molybdopterin binding domain 212 353 6.8E-26 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS17840 546b54467bbc072437eb40301469ca20 440 SUPERFAMILY SSF53218 208 360 1.07E-38 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS17840 546b54467bbc072437eb40301469ca20 440 SUPERFAMILY SSF63867 363 438 3.66E-13 T 23-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS17840 546b54467bbc072437eb40301469ca20 440 Gene3D G3DSA:3.90.105.10 162 193 8.7E-21 T 23-04-2016 DC74_RS17840 546b54467bbc072437eb40301469ca20 440 SUPERFAMILY SSF63882 15 207 6.54E-50 T 23-04-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS17840 546b54467bbc072437eb40301469ca20 440 Gene3D G3DSA:2.170.190.11 57 161 6.5E-34 T 23-04-2016 DC74_RS17840 546b54467bbc072437eb40301469ca20 440 Gene3D G3DSA:2.40.340.10 368 438 1.6E-15 T 23-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 DC74_RS17840 546b54467bbc072437eb40301469ca20 440 PANTHER PTHR10192 16 439 9.3E-152 T 23-04-2016 DC74_RS39390 26739c5ae908afeffc535517158aee8c 150 PANTHER PTHR33204 1 144 5.9E-73 T 23-04-2016 DC74_RS39390 26739c5ae908afeffc535517158aee8c 150 PANTHER PTHR33204:SF3 1 144 5.9E-73 T 23-04-2016 DC74_RS39390 26739c5ae908afeffc535517158aee8c 150 Gene3D G3DSA:1.10.10.10 2 111 1.1E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39390 26739c5ae908afeffc535517158aee8c 150 SUPERFAMILY SSF46785 7 144 1.71E-39 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39390 26739c5ae908afeffc535517158aee8c 150 Pfam PF01638 HxlR-like helix-turn-helix 21 104 6.3E-19 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS34980 83f7275522d2dd76267eae7515915839 219 SUPERFAMILY SSF53955 112 213 3.07E-15 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS34980 83f7275522d2dd76267eae7515915839 219 Pfam PF01464 Transglycosylase SLT domain 144 216 2.1E-10 T 23-04-2016 IPR008258 Transglycosylase SLT domain 1 DC74_RS34980 83f7275522d2dd76267eae7515915839 219 Gene3D G3DSA:1.10.530.10 140 216 4.5E-10 T 23-04-2016 DC74_RS34175 5a89d56b076fb38f9f6c5b3d1331e350 209 PANTHER PTHR30055 2 183 1.5E-28 T 23-04-2016 DC74_RS34175 5a89d56b076fb38f9f6c5b3d1331e350 209 SUPERFAMILY SSF48498 83 185 4.11E-12 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS34175 5a89d56b076fb38f9f6c5b3d1331e350 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.2E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34175 5a89d56b076fb38f9f6c5b3d1331e350 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.1E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34175 5a89d56b076fb38f9f6c5b3d1331e350 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.1E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34175 5a89d56b076fb38f9f6c5b3d1331e350 209 Gene3D G3DSA:1.10.357.10 5 184 2.9E-36 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS34175 5a89d56b076fb38f9f6c5b3d1331e350 209 Pfam PF13977 Bacterial transcriptional repressor 86 185 1.2E-11 T 23-04-2016 DC74_RS34175 5a89d56b076fb38f9f6c5b3d1331e350 209 SUPERFAMILY SSF46689 5 86 2.21E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00405 56f5a5fb50c12583f194488e009375df 406 PANTHER PTHR17630:SF54 5 264 3.0E-57 T 23-04-2016 DC74_RS00405 56f5a5fb50c12583f194488e009375df 406 PANTHER PTHR17630:SF54 336 355 3.0E-57 T 23-04-2016 DC74_RS00405 56f5a5fb50c12583f194488e009375df 406 Gene3D G3DSA:1.20.1440.110 10 122 2.7E-40 T 23-04-2016 DC74_RS00405 56f5a5fb50c12583f194488e009375df 406 SUPERFAMILY SSF53474 12 264 3.24E-66 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS00405 56f5a5fb50c12583f194488e009375df 406 SUPERFAMILY SSF53474 299 401 3.24E-66 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS00405 56f5a5fb50c12583f194488e009375df 406 Pfam PF12697 Alpha/beta hydrolase family 154 354 5.4E-8 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS00405 56f5a5fb50c12583f194488e009375df 406 Gene3D G3DSA:3.40.50.1820 126 403 4.2E-57 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS00405 56f5a5fb50c12583f194488e009375df 406 PANTHER PTHR17630 5 264 3.0E-57 T 23-04-2016 DC74_RS00405 56f5a5fb50c12583f194488e009375df 406 PANTHER PTHR17630 336 355 3.0E-57 T 23-04-2016 DC74_RS19530 f1e01e3c7514a7cae1977a9f212f04da 429 PANTHER PTHR23517:SF2 7 419 8.8E-102 T 23-04-2016 DC74_RS19530 f1e01e3c7514a7cae1977a9f212f04da 429 Pfam PF07690 Major Facilitator Superfamily 14 245 2.8E-20 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS19530 f1e01e3c7514a7cae1977a9f212f04da 429 Pfam PF07690 Major Facilitator Superfamily 246 398 2.7E-12 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS19530 f1e01e3c7514a7cae1977a9f212f04da 429 SUPERFAMILY SSF103473 12 399 5.49E-47 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS19530 f1e01e3c7514a7cae1977a9f212f04da 429 Gene3D G3DSA:1.20.1250.20 14 186 3.3E-21 T 23-04-2016 DC74_RS19530 f1e01e3c7514a7cae1977a9f212f04da 429 Gene3D G3DSA:1.20.1250.20 214 395 5.6E-18 T 23-04-2016 DC74_RS19530 f1e01e3c7514a7cae1977a9f212f04da 429 PANTHER PTHR23517 7 419 8.8E-102 T 23-04-2016 DC74_RS12355 8adbf8f13a7f0d52882f44ba6052ab65 247 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 119 2.7E-24 T 23-04-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 DC74_RS12355 8adbf8f13a7f0d52882f44ba6052ab65 247 SUPERFAMILY SSF54292 2 115 2.91E-21 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS12355 8adbf8f13a7f0d52882f44ba6052ab65 247 Gene3D G3DSA:1.10.1060.10 111 242 8.1E-21 T 23-04-2016 DC74_RS12355 8adbf8f13a7f0d52882f44ba6052ab65 247 SUPERFAMILY SSF46548 118 241 3.49E-25 T 23-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 DC74_RS12355 8adbf8f13a7f0d52882f44ba6052ab65 247 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS12355 8adbf8f13a7f0d52882f44ba6052ab65 247 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 158 169 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS12355 8adbf8f13a7f0d52882f44ba6052ab65 247 PANTHER PTHR11921 3 245 4.2E-128 T 23-04-2016 DC74_RS12355 8adbf8f13a7f0d52882f44ba6052ab65 247 PANTHER PTHR11921:SF13 3 245 4.2E-128 T 23-04-2016 DC74_RS12355 8adbf8f13a7f0d52882f44ba6052ab65 247 Gene3D G3DSA:3.10.20.30 1 110 8.2E-29 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS12355 8adbf8f13a7f0d52882f44ba6052ab65 247 Pfam PF13183 4Fe-4S dicluster domain 157 227 3.2E-10 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS02500 fb143462fdc135ddb5c22510983c83f1 284 SUPERFAMILY SSF53474 48 228 4.59E-28 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02500 fb143462fdc135ddb5c22510983c83f1 284 Gene3D G3DSA:3.40.50.1820 24 280 8.4E-75 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02500 fb143462fdc135ddb5c22510983c83f1 284 PANTHER PTHR32015 50 161 2.7E-12 T 23-04-2016 DC74_RS02500 fb143462fdc135ddb5c22510983c83f1 284 Pfam PF01674 Lipase (class 2) 50 223 6.0E-15 T 23-04-2016 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 DC74_RS18030 ebde627aa77c1550c434117dc0148e90 216 SUPERFAMILY SSF48498 90 197 5.5E-30 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS18030 ebde627aa77c1550c434117dc0148e90 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 4.1E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS18030 ebde627aa77c1550c434117dc0148e90 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 4.1E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS18030 ebde627aa77c1550c434117dc0148e90 216 PANTHER PTHR30055 9 195 2.5E-41 T 23-04-2016 DC74_RS18030 ebde627aa77c1550c434117dc0148e90 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 3.1E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS18030 ebde627aa77c1550c434117dc0148e90 216 PANTHER PTHR30055:SF49 9 195 2.5E-41 T 23-04-2016 DC74_RS18030 ebde627aa77c1550c434117dc0148e90 216 SUPERFAMILY SSF46689 13 96 1.2E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS18030 ebde627aa77c1550c434117dc0148e90 216 Gene3D G3DSA:1.10.357.10 13 200 4.9E-39 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 74 99 3.9E-67 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 305 324 3.9E-67 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 148 166 3.9E-67 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 275 291 3.9E-67 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 416 434 3.9E-67 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 440 458 3.9E-67 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 476 491 3.9E-67 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 166 185 3.9E-67 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 500 517 3.9E-67 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 Pfam PF01019 Gamma-glutamyltranspeptidase 67 593 1.8E-154 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 PANTHER PTHR11686:SF27 45 604 2.1E-261 T 23-04-2016 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 PANTHER PTHR11686 45 604 2.1E-261 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 54 587 3.0E-121 T 23-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 DC74_RS31600 ff2e6d22dea701a35a7ab47f37b2e7a8 605 SUPERFAMILY SSF56235 44 595 9.07E-153 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS05535 51463c89da5379c68a3430de80cfcd6e 226 Pfam PF01569 PAP2 superfamily 125 208 5.0E-9 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS05535 51463c89da5379c68a3430de80cfcd6e 226 Gene3D G3DSA:1.20.144.10 66 211 3.9E-15 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS05535 51463c89da5379c68a3430de80cfcd6e 226 SMART SM00014 96 203 0.0059 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS05535 51463c89da5379c68a3430de80cfcd6e 226 SUPERFAMILY SSF48317 26 213 1.7E-22 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DC74_RS21165 a1ceb8d7bb444ab1ac8212203d019ae2 264 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 259 4.9E-44 T 23-04-2016 IPR023214 HAD-like domain DC74_RS21165 a1ceb8d7bb444ab1ac8212203d019ae2 264 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 77 2.9E-11 T 23-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 DC74_RS21165 a1ceb8d7bb444ab1ac8212203d019ae2 264 Gene3D G3DSA:3.40.50.1000 2 73 1.4E-48 T 23-04-2016 IPR023214 HAD-like domain DC74_RS21165 a1ceb8d7bb444ab1ac8212203d019ae2 264 Gene3D G3DSA:3.40.50.1000 168 262 1.4E-48 T 23-04-2016 IPR023214 HAD-like domain DC74_RS21165 a1ceb8d7bb444ab1ac8212203d019ae2 264 SUPERFAMILY SSF56784 2 262 1.87E-56 T 23-04-2016 IPR023214 HAD-like domain DC74_RS21165 a1ceb8d7bb444ab1ac8212203d019ae2 264 PANTHER PTHR10000:SF8 2 264 5.2E-68 T 23-04-2016 DC74_RS21165 a1ceb8d7bb444ab1ac8212203d019ae2 264 PANTHER PTHR10000 2 264 5.2E-68 T 23-04-2016 DC74_RS07050 820300a6bc66ee71d06918b04f7c4db1 422 SUPERFAMILY SSF54373 187 289 7.45E-14 T 23-04-2016 DC74_RS07050 820300a6bc66ee71d06918b04f7c4db1 422 SUPERFAMILY SSF51905 7 182 7.47E-63 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07050 820300a6bc66ee71d06918b04f7c4db1 422 SUPERFAMILY SSF51905 288 392 7.47E-63 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07050 820300a6bc66ee71d06918b04f7c4db1 422 PANTHER PTHR13789:SF238 8 389 7.8E-87 T 23-04-2016 DC74_RS07050 820300a6bc66ee71d06918b04f7c4db1 422 Pfam PF01494 FAD binding domain 7 362 7.4E-24 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS07050 820300a6bc66ee71d06918b04f7c4db1 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 6.2E-19 T 23-04-2016 DC74_RS07050 820300a6bc66ee71d06918b04f7c4db1 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 6.2E-19 T 23-04-2016 DC74_RS07050 820300a6bc66ee71d06918b04f7c4db1 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 6.2E-19 T 23-04-2016 DC74_RS07050 820300a6bc66ee71d06918b04f7c4db1 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 6.2E-19 T 23-04-2016 DC74_RS07050 820300a6bc66ee71d06918b04f7c4db1 422 PANTHER PTHR13789 8 389 7.8E-87 T 23-04-2016 DC74_RS07050 820300a6bc66ee71d06918b04f7c4db1 422 Gene3D G3DSA:3.50.50.60 6 187 8.2E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07050 820300a6bc66ee71d06918b04f7c4db1 422 Gene3D G3DSA:3.50.50.60 288 373 8.2E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS00640 d750434a261d7a53a1056d51855d8a9a 543 PANTHER PTHR33744:SF3 93 541 3.3E-25 T 23-04-2016 DC74_RS00640 d750434a261d7a53a1056d51855d8a9a 543 PANTHER PTHR33744 93 541 3.3E-25 T 23-04-2016 DC74_RS00640 d750434a261d7a53a1056d51855d8a9a 543 Pfam PF13556 PucR C-terminal helix-turn-helix domain 473 531 2.0E-19 T 23-04-2016 IPR025736 PucR C-terminal helix-turn-helix domain DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PANTHER PTHR24286:SF42 38 406 3.7E-94 T 23-04-2016 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00359 B-class P450 signature 162 177 1.8E-54 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00359 B-class P450 signature 279 290 1.8E-54 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00359 B-class P450 signature 98 109 1.8E-54 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00359 B-class P450 signature 297 324 1.8E-54 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00359 B-class P450 signature 355 366 1.8E-54 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00359 B-class P450 signature 325 340 1.8E-54 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00359 B-class P450 signature 346 355 1.8E-54 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00359 B-class P450 signature 198 220 1.8E-54 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00359 B-class P450 signature 145 161 1.8E-54 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 Pfam PF00067 Cytochrome P450 30 373 5.1E-26 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PANTHER PTHR24286 38 406 3.7E-94 T 23-04-2016 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 Gene3D G3DSA:1.10.630.10 16 406 5.6E-119 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 SUPERFAMILY SSF48264 21 406 2.75E-91 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00385 P450 superfamily signature 244 261 6.6E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00385 P450 superfamily signature 355 366 6.6E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00385 P450 superfamily signature 346 355 6.6E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02255 ef057e3b3f4fbd43d52d88968d5f6e15 406 PRINTS PR00385 P450 superfamily signature 279 290 6.6E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS09425 d3a53bd0277d133afa28a7ae9cca8cf2 278 PANTHER PTHR19278:SF1 5 27 2.7E-67 T 23-04-2016 DC74_RS09425 d3a53bd0277d133afa28a7ae9cca8cf2 278 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 93 106 - T 23-04-2016 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09425 d3a53bd0277d133afa28a7ae9cca8cf2 278 PANTHER PTHR19278 43 236 2.7E-67 T 23-04-2016 DC74_RS09425 d3a53bd0277d133afa28a7ae9cca8cf2 278 PANTHER PTHR19278 5 27 2.7E-67 T 23-04-2016 DC74_RS09425 d3a53bd0277d133afa28a7ae9cca8cf2 278 SUPERFAMILY SSF51366 6 269 5.18E-60 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 DC74_RS09425 d3a53bd0277d133afa28a7ae9cca8cf2 278 SMART SM00934 19 265 3.9E-34 T 23-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09425 d3a53bd0277d133afa28a7ae9cca8cf2 278 PANTHER PTHR19278:SF1 43 236 2.7E-67 T 23-04-2016 DC74_RS09425 d3a53bd0277d133afa28a7ae9cca8cf2 278 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 6 265 3.9E-82 T 23-04-2016 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09425 d3a53bd0277d133afa28a7ae9cca8cf2 278 Gene3D G3DSA:3.20.20.70 8 270 7.4E-57 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS09425 d3a53bd0277d133afa28a7ae9cca8cf2 278 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 4 275 33.173 T 23-04-2016 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS09425 d3a53bd0277d133afa28a7ae9cca8cf2 278 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 19 264 5.6E-37 T 23-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 DC74_RS38280 10f9a657adf578f5a66747c5fc1b8a56 565 Gene3D G3DSA:3.90.76.10 77 191 4.2E-13 T 23-04-2016 DC74_RS38280 10f9a657adf578f5a66747c5fc1b8a56 565 Gene3D G3DSA:3.40.190.10 192 320 5.1E-24 T 23-04-2016 DC74_RS38280 10f9a657adf578f5a66747c5fc1b8a56 565 PIRSF PIRSF002741 5 565 5.2E-52 T 23-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DC74_RS38280 10f9a657adf578f5a66747c5fc1b8a56 565 PANTHER PTHR30290:SF7 1 553 3.8E-71 T 23-04-2016 DC74_RS38280 10f9a657adf578f5a66747c5fc1b8a56 565 SUPERFAMILY SSF53850 56 557 3.8E-84 T 23-04-2016 DC74_RS38280 10f9a657adf578f5a66747c5fc1b8a56 565 Gene3D G3DSA:3.10.105.10 321 536 7.1E-44 T 23-04-2016 DC74_RS38280 10f9a657adf578f5a66747c5fc1b8a56 565 PANTHER PTHR30290 1 553 3.8E-71 T 23-04-2016 DC74_RS38280 10f9a657adf578f5a66747c5fc1b8a56 565 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 111 469 4.9E-54 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain DC74_RS34755 add3c17f620032921c9c3d6a1093156f 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS34755 add3c17f620032921c9c3d6a1093156f 507 PANTHER PTHR11699 1 507 0.0 T 23-04-2016 DC74_RS34755 add3c17f620032921c9c3d6a1093156f 507 SUPERFAMILY SSF53720 13 499 9.69E-162 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS34755 add3c17f620032921c9c3d6a1093156f 507 Pfam PF00171 Aldehyde dehydrogenase family 29 494 6.2E-161 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS34755 add3c17f620032921c9c3d6a1093156f 507 Gene3D G3DSA:3.40.605.10 19 271 9.6E-95 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS34755 add3c17f620032921c9c3d6a1093156f 507 PANTHER PTHR11699:SF97 1 507 0.0 T 23-04-2016 DC74_RS34755 add3c17f620032921c9c3d6a1093156f 507 Gene3D G3DSA:3.40.309.10 272 470 3.0E-56 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS34755 add3c17f620032921c9c3d6a1093156f 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS04590 9e320fb1d5dfb66a8c8b91808c666910 108 SMART SM00706 70 104 7.5E-4 T 23-04-2016 IPR006624 Beta-propeller repeat TECPR DC74_RS35000 331483e82bdda3e1f6d405f3ec1b1512 413 SMART SM00825 Beta-ketoacyl synthase 10 413 7.3E-15 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS35000 331483e82bdda3e1f6d405f3ec1b1512 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 251 6.5E-43 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS35000 331483e82bdda3e1f6d405f3ec1b1512 413 PANTHER PTHR11712 73 412 1.1E-125 T 23-04-2016 DC74_RS35000 331483e82bdda3e1f6d405f3ec1b1512 413 SUPERFAMILY SSF53901 219 412 2.56E-65 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS35000 331483e82bdda3e1f6d405f3ec1b1512 413 Gene3D G3DSA:3.40.47.10 268 412 4.3E-53 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS35000 331483e82bdda3e1f6d405f3ec1b1512 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 260 370 8.3E-34 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS35000 331483e82bdda3e1f6d405f3ec1b1512 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 159 175 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS35000 331483e82bdda3e1f6d405f3ec1b1512 413 SUPERFAMILY SSF53901 10 255 2.39E-60 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS35000 331483e82bdda3e1f6d405f3ec1b1512 413 Gene3D G3DSA:3.40.47.10 12 264 2.1E-59 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS09410 aed83032b6eafb211c16cff4c0620909 91 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 11 83 14.945 T 23-04-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS09410 aed83032b6eafb211c16cff4c0620909 91 Pfam PF01192 RNA polymerase Rpb6 18 80 1.0E-14 T 23-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS09410 aed83032b6eafb211c16cff4c0620909 91 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 12 80 8.8E-22 T 23-04-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS09410 aed83032b6eafb211c16cff4c0620909 91 SUPERFAMILY SSF63562 11 86 1.1E-24 T 23-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS09410 aed83032b6eafb211c16cff4c0620909 91 Gene3D G3DSA:3.90.940.10 11 84 6.8E-34 T 23-04-2016 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS09410 aed83032b6eafb211c16cff4c0620909 91 PANTHER PTHR34476 12 86 1.9E-24 T 23-04-2016 DC74_RS09410 aed83032b6eafb211c16cff4c0620909 91 SMART SM01409 18 82 2.2E-14 T 23-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DC74_RS17995 086c6628e54a79be63bafd6a68b9c989 175 SUPERFAMILY SSF55729 11 174 8.19E-27 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS17995 086c6628e54a79be63bafd6a68b9c989 175 Gene3D G3DSA:3.40.630.30 8 174 4.8E-33 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS17995 086c6628e54a79be63bafd6a68b9c989 175 PANTHER PTHR23091:SF187 10 174 2.6E-23 T 23-04-2016 DC74_RS17995 086c6628e54a79be63bafd6a68b9c989 175 PANTHER PTHR23091 10 174 2.6E-23 T 23-04-2016 DC74_RS17995 086c6628e54a79be63bafd6a68b9c989 175 Pfam PF13420 Acetyltransferase (GNAT) domain 11 169 5.4E-20 T 23-04-2016 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 PANTHER PTHR23429:SF0 13 510 1.6E-240 T 23-04-2016 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 PANTHER PTHR23429 13 510 1.6E-240 T 23-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 191 219 8.1E-48 T 23-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 243 260 8.1E-48 T 23-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 350 376 8.1E-48 T 23-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 261 277 8.1E-48 T 23-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 167 180 8.1E-48 T 23-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 24 509 88.452 T 23-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 Gene3D G3DSA:3.30.360.10 211 508 3.8E-122 T 23-04-2016 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 SUPERFAMILY SSF55347 201 508 9.48E-115 T 23-04-2016 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 28 211 1.2E-63 T 23-04-2016 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 Gene3D G3DSA:3.40.50.720 24 210 8.2E-71 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 26 509 1.7E-202 T 23-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 201 207 - T 23-04-2016 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 213 508 2.6E-115 T 23-04-2016 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 PIRSF PIRSF000110 11 510 3.7E-181 T 23-04-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 DC74_RS11785 5204e7dc1855a9c83b7ff7a59768ce0d 510 SUPERFAMILY SSF51735 14 214 1.1E-62 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37420 8e4400e3d081174aa7dd469679dbf6ae 371 PANTHER PTHR40032 212 352 1.7E-18 T 23-04-2016 DC74_RS37420 8e4400e3d081174aa7dd469679dbf6ae 371 Pfam PF12671 Putative amidase domain 215 368 3.0E-35 T 23-04-2016 IPR024301 Putative amidase domain DC74_RS37420 8e4400e3d081174aa7dd469679dbf6ae 371 PANTHER PTHR40032:SF2 212 352 1.7E-18 T 23-04-2016 DC74_RS08125 be28c1dc3617b90ac3071348e1569cb2 307 Pfam PF05949 Bacterial protein of unknown function (DUF881) 136 287 2.4E-39 T 23-04-2016 IPR010273 Protein of unknown function DUF881 DC74_RS08125 be28c1dc3617b90ac3071348e1569cb2 307 PANTHER PTHR37313 17 293 1.5E-124 T 23-04-2016 DC74_RS08125 be28c1dc3617b90ac3071348e1569cb2 307 PANTHER PTHR37313:SF1 17 293 1.5E-124 T 23-04-2016 DC74_RS28275 5849b25c2af5e7bee901f491d996ec90 453 SUPERFAMILY SSF53383 9 448 1.6E-122 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS28275 5849b25c2af5e7bee901f491d996ec90 453 Gene3D G3DSA:3.90.1150.10 340 448 7.0E-34 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS28275 5849b25c2af5e7bee901f491d996ec90 453 Gene3D G3DSA:3.90.1150.10 3 63 7.0E-34 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS28275 5849b25c2af5e7bee901f491d996ec90 453 Pfam PF00202 Aminotransferase class-III 29 445 6.9E-99 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS28275 5849b25c2af5e7bee901f491d996ec90 453 PANTHER PTHR11986 4 453 8.2E-261 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS28275 5849b25c2af5e7bee901f491d996ec90 453 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS28275 5849b25c2af5e7bee901f491d996ec90 453 PANTHER PTHR11986:SF89 4 453 8.2E-261 T 23-04-2016 DC74_RS28275 5849b25c2af5e7bee901f491d996ec90 453 Gene3D G3DSA:3.40.640.10 65 338 6.1E-83 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS10350 07ca9a792dddb00121fba2660b1a9944 431 PANTHER PTHR11911:SF77 206 424 6.7E-37 T 23-04-2016 DC74_RS10350 07ca9a792dddb00121fba2660b1a9944 431 PANTHER PTHR11911 206 424 6.7E-37 T 23-04-2016 DC74_RS10350 07ca9a792dddb00121fba2660b1a9944 431 Gene3D G3DSA:3.10.580.10 308 423 1.7E-7 T 23-04-2016 DC74_RS10350 07ca9a792dddb00121fba2660b1a9944 431 PIRSF PIRSF006404 51 431 2.6E-103 T 23-04-2016 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS DC74_RS10350 07ca9a792dddb00121fba2660b1a9944 431 SUPERFAMILY SSF54631 308 424 1.97E-8 T 23-04-2016 DC74_RS10350 07ca9a792dddb00121fba2660b1a9944 431 Pfam PF02163 Peptidase family M50 187 235 3.8E-8 T 23-04-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 DC74_RS05065 bd0ca617908ba45ba2231a6e285ed7b9 71 Pfam PF00403 Heavy-metal-associated domain 7 63 9.2E-16 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 DC74_RS05065 bd0ca617908ba45ba2231a6e285ed7b9 71 SUPERFAMILY SSF55008 2 66 5.76E-18 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 DC74_RS05065 bd0ca617908ba45ba2231a6e285ed7b9 71 PRINTS PR00944 Copper ion binding protein signature 52 65 1.7E-5 T 23-04-2016 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 DC74_RS05065 bd0ca617908ba45ba2231a6e285ed7b9 71 PRINTS PR00944 Copper ion binding protein signature 15 28 1.7E-5 T 23-04-2016 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 DC74_RS05065 bd0ca617908ba45ba2231a6e285ed7b9 71 PRINTS PR00944 Copper ion binding protein signature 3 15 1.7E-5 T 23-04-2016 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 DC74_RS05065 bd0ca617908ba45ba2231a6e285ed7b9 71 PRINTS PR00944 Copper ion binding protein signature 28 41 1.7E-5 T 23-04-2016 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 DC74_RS05065 bd0ca617908ba45ba2231a6e285ed7b9 71 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 23-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 DC74_RS05065 bd0ca617908ba45ba2231a6e285ed7b9 71 Gene3D G3DSA:3.30.70.100 3 65 8.5E-22 T 23-04-2016 DC74_RS11535 39a73e87931de0f183836356164d750a 304 Gene3D G3DSA:3.40.50.1400 137 271 1.2E-22 T 23-04-2016 DC74_RS11535 39a73e87931de0f183836356164d750a 304 Gene3D G3DSA:3.40.50.1400 6 126 2.6E-22 T 23-04-2016 DC74_RS11535 39a73e87931de0f183836356164d750a 304 PANTHER PTHR33542:SF2 1 271 5.3E-46 T 23-04-2016 DC74_RS11535 39a73e87931de0f183836356164d750a 304 SUPERFAMILY SSF53800 5 269 8.29E-37 T 23-04-2016 DC74_RS11535 39a73e87931de0f183836356164d750a 304 PANTHER PTHR33542 1 271 5.3E-46 T 23-04-2016 DC74_RS11535 39a73e87931de0f183836356164d750a 304 Pfam PF01903 CbiX 145 262 3.4E-15 T 23-04-2016 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377|UniPathway: UPA00148 DC74_RS11535 39a73e87931de0f183836356164d750a 304 Pfam PF01903 CbiX 12 118 5.4E-16 T 23-04-2016 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377|UniPathway: UPA00148 DC74_RS29245 de6e1f88c6aa0d5d86740bc8117a54ad 683 PANTHER PTHR11785 35 515 5.7E-184 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS29245 de6e1f88c6aa0d5d86740bc8117a54ad 683 Pfam PF13520 Amino acid permease 59 465 1.2E-33 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS29245 de6e1f88c6aa0d5d86740bc8117a54ad 683 PANTHER PTHR11785:SF125 35 515 5.7E-184 T 23-04-2016 DC74_RS32985 1950d6fdbd8c535d40aaf4aedfb82477 240 Pfam PF04493 Endonuclease V 48 230 4.3E-64 T 23-04-2016 IPR007581 Endonuclease V GO:0004519|GO:0006281 DC74_RS32985 1950d6fdbd8c535d40aaf4aedfb82477 240 PANTHER PTHR28511:SF1 1 237 1.6E-64 T 23-04-2016 DC74_RS32985 1950d6fdbd8c535d40aaf4aedfb82477 240 Hamap MF_00801 Endonuclease V [nfi]. 19 240 32.533 T 23-04-2016 IPR007581 Endonuclease V GO:0004519|GO:0006281 DC74_RS32985 1950d6fdbd8c535d40aaf4aedfb82477 240 PANTHER PTHR28511 1 237 1.6E-64 T 23-04-2016 DC74_RS09340 f5bf615c6d47119f90cd58728006d275 329 PANTHER PTHR34294 1 314 2.9E-119 T 23-04-2016 DC74_RS09340 f5bf615c6d47119f90cd58728006d275 329 PANTHER PTHR34294:SF5 1 314 2.9E-119 T 23-04-2016 DC74_RS09340 f5bf615c6d47119f90cd58728006d275 329 SUPERFAMILY SSF100950 65 310 6.7E-56 T 23-04-2016 DC74_RS09340 f5bf615c6d47119f90cd58728006d275 329 Pfam PF04198 Putative sugar-binding domain 62 310 3.8E-66 T 23-04-2016 IPR007324 Sugar-binding domain, putative GO:0030246 DC74_RS09340 f5bf615c6d47119f90cd58728006d275 329 Gene3D G3DSA:3.40.50.1360 54 310 2.3E-68 T 23-04-2016 DC74_RS16450 f55d7910feccf99ce649b40878c5d0d8 96 Gene3D G3DSA:3.30.1390.10 66 92 1.7E-5 T 23-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like DC74_RS16450 f55d7910feccf99ce649b40878c5d0d8 96 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 66 93 1.4E-5 T 23-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 SUPERFAMILY SSF51735 113 292 9.87E-58 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 SUPERFAMILY SSF55021 465 537 1.83E-15 T 23-04-2016 DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 PANTHER PTHR10996 4 366 3.8E-163 T 23-04-2016 DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 Gene3D G3DSA:3.40.50.720 119 294 8.7E-68 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 Gene3D G3DSA:3.30.1330.90 329 457 5.2E-41 T 23-04-2016 IPR029009 Allosteric substrate binding domain DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 Gene3D G3DSA:3.40.50.720 14 118 7.4E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 SUPERFAMILY SSF143548 331 460 1.05E-31 T 23-04-2016 IPR029009 Allosteric substrate binding domain DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 292 7.1E-61 T 23-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 203 225 - T 23-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 SUPERFAMILY SSF52283 14 146 1.08E-36 T 23-04-2016 DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 324 7.1E-33 T 23-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 Pfam PF01842 ACT domain 469 526 8.1E-10 T 23-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 232 248 - T 23-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 Gene3D G3DSA:3.30.70.260 458 535 5.7E-17 T 23-04-2016 DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 155 182 - T 23-04-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 PANTHER PTHR10996:SF20 4 366 3.8E-163 T 23-04-2016 DC74_RS27700 e8e556fa4ae9d8f7aea5f8b868dd4205 540 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 17 538 5.1E-185 T 23-04-2016 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|UniPathway: UPA00135 DC74_RS22325 fbe304ee295f6d081ff4d73220233b9c 84 PANTHER PTHR33280:SF3 1 80 4.7E-33 T 23-04-2016 DC74_RS22325 fbe304ee295f6d081ff4d73220233b9c 84 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.32 T 23-04-2016 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22325 fbe304ee295f6d081ff4d73220233b9c 84 SUPERFAMILY SSF143800 1 80 3.53E-21 T 23-04-2016 DC74_RS22325 fbe304ee295f6d081ff4d73220233b9c 84 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22325 fbe304ee295f6d081ff4d73220233b9c 84 Pfam PF01197 Ribosomal protein L31 1 79 1.2E-28 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22325 fbe304ee295f6d081ff4d73220233b9c 84 PRINTS PR01249 Ribosomal protein L31 signature 60 78 1.2E-17 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22325 fbe304ee295f6d081ff4d73220233b9c 84 PRINTS PR01249 Ribosomal protein L31 signature 45 60 1.2E-17 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22325 fbe304ee295f6d081ff4d73220233b9c 84 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.2E-17 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22325 fbe304ee295f6d081ff4d73220233b9c 84 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 1.1E-18 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22325 fbe304ee295f6d081ff4d73220233b9c 84 PANTHER PTHR33280 1 80 4.7E-33 T 23-04-2016 DC74_RS25855 7b38f06871e6c3d40398872db7fe7ab0 344 Gene3D G3DSA:1.10.3720.10 122 340 1.0E-23 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS25855 7b38f06871e6c3d40398872db7fe7ab0 344 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 37 82 2.5E-9 T 23-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain DC74_RS25855 7b38f06871e6c3d40398872db7fe7ab0 344 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 147 341 1.1E-29 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS25855 7b38f06871e6c3d40398872db7fe7ab0 344 PANTHER PTHR30465:SF69 32 344 3.6E-146 T 23-04-2016 DC74_RS25855 7b38f06871e6c3d40398872db7fe7ab0 344 PANTHER PTHR30465 32 344 3.6E-146 T 23-04-2016 DC74_RS25855 7b38f06871e6c3d40398872db7fe7ab0 344 SUPERFAMILY SSF161098 124 329 7.59E-24 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS31995 c05037b187d359c2496ae5ae44b1c94d 328 SUPERFAMILY SSF53335 228 268 4.45E-32 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS31995 c05037b187d359c2496ae5ae44b1c94d 328 SUPERFAMILY SSF53335 81 196 4.45E-32 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS31995 c05037b187d359c2496ae5ae44b1c94d 328 PANTHER PTHR10108 86 188 4.0E-17 T 23-04-2016 DC74_RS31995 c05037b187d359c2496ae5ae44b1c94d 328 Gene3D G3DSA:3.40.50.150 84 249 1.4E-28 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS31995 c05037b187d359c2496ae5ae44b1c94d 328 Pfam PF13649 Methyltransferase domain 88 184 3.2E-15 T 23-04-2016 DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 Gene3D G3DSA:3.40.50.300 661 726 4.4E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 Pfam PF14520 Helix-hairpin-helix domain 94 138 1.5E-6 T 23-04-2016 DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 PANTHER PTHR10887 675 728 6.1E-109 T 23-04-2016 DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 PANTHER PTHR10887 286 606 6.1E-109 T 23-04-2016 DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 SMART SM00382 349 562 0.0037 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 Pfam PF14490 Helix-hairpin-helix containing domain 144 234 2.3E-30 T 23-04-2016 IPR029493 RecD helicase-like helix-hairpin-helix domain DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 Pfam PF13538 UvrD-like helicase C-terminal domain 674 722 9.7E-20 T 23-04-2016 IPR027785 UvrD-like helicase C-terminal domain DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 4 751 28.933 T 23-04-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 PANTHER PTHR10887:SF284 675 728 6.1E-109 T 23-04-2016 DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 PANTHER PTHR10887:SF284 286 606 6.1E-109 T 23-04-2016 DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 Pfam PF13604 AAA domain 335 529 1.8E-41 T 23-04-2016 DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 SUPERFAMILY SSF47781 86 162 6.95E-9 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 Gene3D G3DSA:3.40.50.300 302 527 3.3E-40 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 SUPERFAMILY SSF52540 329 726 8.36E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15770 06abdba37966bd8f2c0a6bc478de2237 752 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 8 747 3.3E-193 T 23-04-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 DC74_RS02525 c35c11ae8d1e468251969b9083b57164 183 SUPERFAMILY SSF143744 49 181 2.88E-31 T 23-04-2016 DC74_RS02525 c35c11ae8d1e468251969b9083b57164 183 Pfam PF03928 Haem-degrading 56 178 3.7E-28 T 23-04-2016 IPR005624 Haem-degrading DC74_RS02525 c35c11ae8d1e468251969b9083b57164 183 PANTHER PTHR34309:SF1 23 181 8.5E-38 T 23-04-2016 DC74_RS02525 c35c11ae8d1e468251969b9083b57164 183 PANTHER PTHR34309 23 181 8.5E-38 T 23-04-2016 DC74_RS35995 2eda75e58565b4da9310015caa0f5931 481 Pfam PF13520 Amino acid permease 35 430 2.2E-31 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS35995 2eda75e58565b4da9310015caa0f5931 481 PANTHER PTHR11785 29 460 2.3E-78 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS35995 2eda75e58565b4da9310015caa0f5931 481 PANTHER PTHR11785:SF261 29 460 2.3E-78 T 23-04-2016 DC74_RS35995 2eda75e58565b4da9310015caa0f5931 481 PIRSF PIRSF006060 15 468 1.3E-54 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS36470 23ed2d2a7a2af58e54e397d705850e11 340 Gene3D G3DSA:2.120.10.30 133 327 8.3E-15 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS36470 23ed2d2a7a2af58e54e397d705850e11 340 Pfam PF07676 WD40-like Beta Propeller Repeat 243 257 0.0048 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS36470 23ed2d2a7a2af58e54e397d705850e11 340 SUPERFAMILY SSF82171 116 327 1.75E-15 T 23-04-2016 DC74_RS36470 23ed2d2a7a2af58e54e397d705850e11 340 SUPERFAMILY SSF82171 62 81 1.75E-15 T 23-04-2016 DC74_RS27475 29f7514ccf1950949c6847e32038c985 237 Pfam PF13671 AAA domain 64 207 1.6E-8 T 23-04-2016 DC74_RS27475 29f7514ccf1950949c6847e32038c985 237 SUPERFAMILY SSF52540 57 203 2.19E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27475 29f7514ccf1950949c6847e32038c985 237 Gene3D G3DSA:3.40.50.300 64 194 3.6E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38890 581d028e3a8cd4c65c284854c4790b80 292 SUPERFAMILY SSF53335 20 289 4.69E-30 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS38890 581d028e3a8cd4c65c284854c4790b80 292 Pfam PF08241 Methyltransferase domain 102 197 1.3E-9 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS38890 581d028e3a8cd4c65c284854c4790b80 292 Gene3D G3DSA:3.40.50.150 16 276 1.3E-33 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS38890 581d028e3a8cd4c65c284854c4790b80 292 PANTHER PTHR10108 42 278 4.4E-17 T 23-04-2016 DC74_RS08515 7df1ea9b14e3a9d9dc6feb297e5ef5d8 313 PANTHER PTHR23091 132 293 3.0E-21 T 23-04-2016 DC74_RS08515 7df1ea9b14e3a9d9dc6feb297e5ef5d8 313 SUPERFAMILY SSF55729 6 138 6.55E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS08515 7df1ea9b14e3a9d9dc6feb297e5ef5d8 313 Gene3D G3DSA:3.40.630.30 142 292 2.0E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS08515 7df1ea9b14e3a9d9dc6feb297e5ef5d8 313 SUPERFAMILY SSF55729 120 294 3.93E-30 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS08515 7df1ea9b14e3a9d9dc6feb297e5ef5d8 313 Pfam PF00583 Acetyltransferase (GNAT) family 84 136 8.3E-7 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS08515 7df1ea9b14e3a9d9dc6feb297e5ef5d8 313 Pfam PF00583 Acetyltransferase (GNAT) family 214 290 9.1E-16 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS08515 7df1ea9b14e3a9d9dc6feb297e5ef5d8 313 Gene3D G3DSA:3.40.630.30 11 138 3.0E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS11040 33d1649ad9056ac9330723a4c99b1014 357 Pfam PF02616 Segregation and condensation protein ScpA 99 319 5.1E-52 T 23-04-2016 IPR003768 Segregation and condensation protein A DC74_RS11040 33d1649ad9056ac9330723a4c99b1014 357 PANTHER PTHR33969 66 338 4.6E-71 T 23-04-2016 DC74_RS11040 33d1649ad9056ac9330723a4c99b1014 357 PANTHER PTHR33969:SF2 66 338 4.6E-71 T 23-04-2016 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 21 471 1.4E-96 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 Gene3D G3DSA:1.20.1250.20 274 470 1.9E-19 T 23-04-2016 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 Gene3D G3DSA:1.20.1250.20 29 221 7.4E-23 T 23-04-2016 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 PANTHER PTHR23503:SF24 7 471 0.0 T 23-04-2016 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 ProSitePatterns PS00217 Sugar transport proteins signature 2. 122 147 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 PRINTS PR00171 Sugar transporter signature 377 398 7.2E-21 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 PRINTS PR00171 Sugar transporter signature 117 136 7.2E-21 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 PRINTS PR00171 Sugar transporter signature 34 44 7.2E-21 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 PRINTS PR00171 Sugar transporter signature 400 412 7.2E-21 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 PRINTS PR00171 Sugar transporter signature 284 294 7.2E-21 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 PANTHER PTHR23503 7 471 0.0 T 23-04-2016 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 Pfam PF00083 Sugar (and other) transporter 27 471 7.6E-104 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 ProSitePatterns PS00216 Sugar transport proteins signature 1. 328 345 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS28040 49aaa5875cd9d51f49c6d8dd8f4308ca 472 SUPERFAMILY SSF103473 22 471 1.09E-67 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS23735 0f27a3dfb4f8b0c054690e8cae93d8b4 137 PANTHER PTHR36222 1 134 7.7E-49 T 23-04-2016 DC74_RS23735 0f27a3dfb4f8b0c054690e8cae93d8b4 137 SMART SM00960 9 101 1.1E-28 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS23735 0f27a3dfb4f8b0c054690e8cae93d8b4 137 SUPERFAMILY SSF103196 2 130 6.54E-34 T 23-04-2016 DC74_RS23735 0f27a3dfb4f8b0c054690e8cae93d8b4 137 Gene3D G3DSA:3.30.450.30 7 128 1.4E-31 T 23-04-2016 DC74_RS23735 0f27a3dfb4f8b0c054690e8cae93d8b4 137 Pfam PF03259 Roadblock/LC7 domain 8 101 1.3E-25 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS33785 717f6c425e33392587d3e61ead891058 531 PIRSF PIRSF002741 1 524 1.7E-109 T 23-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DC74_RS33785 717f6c425e33392587d3e61ead891058 531 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 436 5.2E-93 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain DC74_RS33785 717f6c425e33392587d3e61ead891058 531 PANTHER PTHR30290 1 531 9.0E-207 T 23-04-2016 DC74_RS33785 717f6c425e33392587d3e61ead891058 531 Gene3D G3DSA:3.90.76.10 48 192 1.3E-40 T 23-04-2016 DC74_RS33785 717f6c425e33392587d3e61ead891058 531 Gene3D G3DSA:3.10.105.10 294 491 4.0E-42 T 23-04-2016 DC74_RS33785 717f6c425e33392587d3e61ead891058 531 Gene3D G3DSA:3.40.190.10 193 293 1.6E-33 T 23-04-2016 DC74_RS33785 717f6c425e33392587d3e61ead891058 531 SUPERFAMILY SSF53850 36 522 2.17E-122 T 23-04-2016 DC74_RS33785 717f6c425e33392587d3e61ead891058 531 PANTHER PTHR30290:SF27 1 531 9.0E-207 T 23-04-2016 DC74_RS01950 eac4c96c8646288ccd26d814fb43e3ab 314 Pfam PF13091 PLD-like domain 179 306 5.7E-19 T 23-04-2016 IPR025202 Phospholipase D-like domain DC74_RS01950 eac4c96c8646288ccd26d814fb43e3ab 314 Pfam PF13091 PLD-like domain 33 154 3.7E-16 T 23-04-2016 IPR025202 Phospholipase D-like domain DC74_RS01950 eac4c96c8646288ccd26d814fb43e3ab 314 PANTHER PTHR21248 31 307 2.4E-19 T 23-04-2016 DC74_RS01950 eac4c96c8646288ccd26d814fb43e3ab 314 SUPERFAMILY SSF56024 167 310 6.95E-22 T 23-04-2016 DC74_RS01950 eac4c96c8646288ccd26d814fb43e3ab 314 Gene3D G3DSA:3.30.870.10 25 159 2.7E-22 T 23-04-2016 DC74_RS01950 eac4c96c8646288ccd26d814fb43e3ab 314 Gene3D G3DSA:3.30.870.10 167 311 2.9E-24 T 23-04-2016 DC74_RS01950 eac4c96c8646288ccd26d814fb43e3ab 314 SUPERFAMILY SSF56024 12 158 2.02E-22 T 23-04-2016 DC74_RS13895 67e6c89146a145395e1e686252036354 234 SMART SM00895 106 228 1.9E-19 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS13895 67e6c89146a145395e1e686252036354 234 SMART SM00345 19 77 2.8E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS13895 67e6c89146a145395e1e686252036354 234 Gene3D G3DSA:1.10.10.10 20 89 4.1E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13895 67e6c89146a145395e1e686252036354 234 SUPERFAMILY SSF48008 104 231 6.8E-23 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS13895 67e6c89146a145395e1e686252036354 234 Pfam PF07729 FCD domain 106 227 7.1E-22 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS13895 67e6c89146a145395e1e686252036354 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 77 1.9E-13 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS13895 67e6c89146a145395e1e686252036354 234 Gene3D G3DSA:1.20.120.530 104 231 7.7E-21 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS13895 67e6c89146a145395e1e686252036354 234 PANTHER PTHR11751 20 84 2.3E-21 T 23-04-2016 DC74_RS13895 67e6c89146a145395e1e686252036354 234 PANTHER PTHR11751 104 122 2.3E-21 T 23-04-2016 DC74_RS13895 67e6c89146a145395e1e686252036354 234 SUPERFAMILY SSF46785 15 81 4.01E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28930 108d95c4ecb36fa5a5630e85989c768d 175 Pfam PF03477 ATP cone domain 47 132 3.0E-13 T 23-04-2016 IPR005144 ATP-cone domain DC74_RS28930 108d95c4ecb36fa5a5630e85989c768d 175 PANTHER PTHR30455 2 153 2.3E-65 T 23-04-2016 DC74_RS28930 108d95c4ecb36fa5a5630e85989c768d 175 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 77.134 T 23-04-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 DC74_RS28930 108d95c4ecb36fa5a5630e85989c768d 175 PANTHER PTHR30455:SF2 2 153 2.3E-65 T 23-04-2016 DC74_RS28930 108d95c4ecb36fa5a5630e85989c768d 175 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 3.6E-45 T 23-04-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 DC74_RS36870 c58706e7041ee3d56226c6410a666a83 474 Pfam PF04213 Htaa 45 211 2.0E-48 T 23-04-2016 IPR007331 Htaa DC74_RS36870 c58706e7041ee3d56226c6410a666a83 474 Pfam PF04213 Htaa 243 393 1.6E-43 T 23-04-2016 IPR007331 Htaa DC74_RS27815 d703aa14c7c1d599fff5f678c1ccd68b 192 PANTHER PTHR11711 17 192 1.0E-58 T 23-04-2016 DC74_RS27815 d703aa14c7c1d599fff5f678c1ccd68b 192 PANTHER PTHR11711:SF117 17 192 1.0E-58 T 23-04-2016 DC74_RS27815 d703aa14c7c1d599fff5f678c1ccd68b 192 Gene3D G3DSA:3.40.50.300 11 186 1.2E-15 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27815 d703aa14c7c1d599fff5f678c1ccd68b 192 SUPERFAMILY SSF52540 15 186 1.79E-22 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27815 d703aa14c7c1d599fff5f678c1ccd68b 192 Pfam PF03029 Conserved hypothetical ATP binding protein 20 187 2.4E-27 T 23-04-2016 IPR004130 GPN-loop GTPase DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 Gene3D G3DSA:3.40.50.720 4 250 1.8E-82 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 1.3E-6 T 23-04-2016 DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.3E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.3E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.3E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 PANTHER PTHR24322 11 186 7.4E-56 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 SUPERFAMILY SSF51735 5 250 4.29E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 2.5E-61 T 23-04-2016 DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07590 dcf1cd65905a4ab0fc27204007da11b1 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS02840 74e7aff594ed194e36e63f02a4f00ce0 305 SUPERFAMILY SSF53474 46 302 2.81E-42 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02840 74e7aff594ed194e36e63f02a4f00ce0 305 PANTHER PTHR10992 46 303 1.9E-38 T 23-04-2016 DC74_RS02840 74e7aff594ed194e36e63f02a4f00ce0 305 PANTHER PTHR10992:SF771 46 303 1.9E-38 T 23-04-2016 DC74_RS02840 74e7aff594ed194e36e63f02a4f00ce0 305 Pfam PF12697 Alpha/beta hydrolase family 71 295 5.3E-18 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS02840 74e7aff594ed194e36e63f02a4f00ce0 305 Gene3D G3DSA:3.40.50.1820 41 302 2.7E-47 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS22015 b82083f5e666c40d13e396eb67e006e9 114 Pfam PF02467 Transcription factor WhiB 7 69 9.2E-25 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS22015 b82083f5e666c40d13e396eb67e006e9 114 PANTHER PTHR38839 6 86 7.5E-37 T 23-04-2016 DC74_RS22015 b82083f5e666c40d13e396eb67e006e9 114 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 82 15.968 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS22015 b82083f5e666c40d13e396eb67e006e9 114 PANTHER PTHR38839:SF3 6 86 7.5E-37 T 23-04-2016 DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 PANTHER PTHR24362 36 333 1.9E-118 T 23-04-2016 DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 PANTHER PTHR24362 410 439 1.9E-118 T 23-04-2016 DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 44 67 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 Gene3D G3DSA:1.10.510.10 407 471 2.1E-51 T 23-04-2016 DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 Gene3D G3DSA:1.10.510.10 127 301 2.1E-51 T 23-04-2016 DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 Pfam PF00069 Protein kinase domain 38 293 3.8E-48 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 PANTHER PTHR24362:SF160 36 333 1.9E-118 T 23-04-2016 DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 PANTHER PTHR24362:SF160 410 439 1.9E-118 T 23-04-2016 DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 SUPERFAMILY SSF56112 36 302 6.07E-75 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 SUPERFAMILY SSF56112 407 474 6.07E-75 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 SMART SM00220 38 300 8.5E-58 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 Gene3D G3DSA:3.30.200.20 34 121 2.7E-24 T 23-04-2016 DC74_RS20375 8c1ec419af2e023c8a22f0d13b1c2347 555 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 161 173 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS23790 7d5a45b79914cec51627dce7e4cfc815 188 Gene3D G3DSA:3.90.1140.10 1 187 3.9E-53 T 23-04-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase DC74_RS23790 7d5a45b79914cec51627dce7e4cfc815 188 PANTHER PTHR35561 1 188 6.3E-40 T 23-04-2016 DC74_RS23790 7d5a45b79914cec51627dce7e4cfc815 188 SUPERFAMILY SSF55144 1 188 3.49E-38 T 23-04-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase DC74_RS23790 7d5a45b79914cec51627dce7e4cfc815 188 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 186 2.4E-32 T 23-04-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 DC74_RS23790 7d5a45b79914cec51627dce7e4cfc815 188 Pfam PF13563 2'-5' RNA ligase superfamily 16 164 1.5E-16 T 23-04-2016 DC74_RS23790 7d5a45b79914cec51627dce7e4cfc815 188 PANTHER PTHR35561:SF1 1 188 6.3E-40 T 23-04-2016 DC74_RS23790 7d5a45b79914cec51627dce7e4cfc815 188 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 186 22.042 T 23-04-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 DC74_RS10035 4874b6545d02e43e90caaa9b7fb7489b 83 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 16 81 4.9E-15 T 23-04-2016 IPR008792 Coenzyme PQQ synthesis D UniPathway: UPA00539 DC74_RS38020 c6dbb0bfc53cfa053566bdcb868dfc43 471 SUPERFAMILY SSF52317 177 280 5.95E-7 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS10325 02c955b96d00b5b7a59e0fb07b0df6a0 497 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 1 484 3.8E-245 T 23-04-2016 IPR022366 Pup deamidase GO:0008233|GO:0016811 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.-|UniPathway: UPA00997 DC74_RS10325 02c955b96d00b5b7a59e0fb07b0df6a0 497 PIRSF PIRSF018077 4 494 3.1E-218 T 23-04-2016 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 UniPathway: UPA00997|UniPathway: UPA00998 DC74_RS10325 02c955b96d00b5b7a59e0fb07b0df6a0 497 PANTHER PTHR42307:SF2 1 496 5.6E-269 T 23-04-2016 DC74_RS10325 02c955b96d00b5b7a59e0fb07b0df6a0 497 PANTHER PTHR42307 1 496 5.6E-269 T 23-04-2016 DC74_RS10325 02c955b96d00b5b7a59e0fb07b0df6a0 497 Pfam PF03136 Pup-ligase protein 1 451 3.5E-190 T 23-04-2016 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 UniPathway: UPA00997|UniPathway: UPA00998 DC74_RS33700 d876d9166b9e2e5ea6dc58e2e02eaed0 310 PANTHER PTHR13593:SF43 44 310 1.7E-46 T 23-04-2016 DC74_RS33700 d876d9166b9e2e5ea6dc58e2e02eaed0 310 Gene3D G3DSA:3.20.20.190 40 297 5.6E-61 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS33700 d876d9166b9e2e5ea6dc58e2e02eaed0 310 Pfam PF00388 Phosphatidylinositol-specific phospholipase C, X domain 76 187 1.3E-9 T 23-04-2016 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain DC74_RS33700 d876d9166b9e2e5ea6dc58e2e02eaed0 310 SMART SM00148 51 190 3.2E-7 T 23-04-2016 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain DC74_RS33700 d876d9166b9e2e5ea6dc58e2e02eaed0 310 PANTHER PTHR13593 44 310 1.7E-46 T 23-04-2016 DC74_RS33700 d876d9166b9e2e5ea6dc58e2e02eaed0 310 SUPERFAMILY SSF51695 42 297 3.03E-50 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS11570 5db05171cf76036072722cc0b0b60bf0 363 PANTHER PTHR11271:SF42 6 362 6.2E-119 T 23-04-2016 DC74_RS11570 5db05171cf76036072722cc0b0b60bf0 363 Pfam PF01979 Amidohydrolase family 48 362 4.6E-15 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS11570 5db05171cf76036072722cc0b0b60bf0 363 SUPERFAMILY SSF51556 52 326 9.83E-62 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS11570 5db05171cf76036072722cc0b0b60bf0 363 Gene3D G3DSA:2.30.40.10 33 53 4.1E-7 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS11570 5db05171cf76036072722cc0b0b60bf0 363 Gene3D G3DSA:2.30.40.10 325 362 4.1E-7 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS11570 5db05171cf76036072722cc0b0b60bf0 363 Gene3D G3DSA:3.20.20.140 54 324 1.2E-64 T 23-04-2016 DC74_RS11570 5db05171cf76036072722cc0b0b60bf0 363 PANTHER PTHR11271 6 362 6.2E-119 T 23-04-2016 DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 SUPERFAMILY SSF55874 578 697 3.8E-15 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 590 697 3.2E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 PANTHER PTHR24423:SF468 455 471 1.9E-83 T 23-04-2016 DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 Pfam PF08376 Nitrate and nitrite sensing 105 366 1.3E-38 T 23-04-2016 IPR013587 Nitrate/nitrite sensing protein DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 Pfam PF00672 HAMP domain 387 471 4.8E-11 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 PANTHER PTHR24423:SF468 399 437 1.9E-83 T 23-04-2016 DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 PANTHER PTHR24423:SF468 1 11 1.9E-83 T 23-04-2016 DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 PANTHER PTHR24423 1 11 1.9E-83 T 23-04-2016 DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 PANTHER PTHR24423 399 437 1.9E-83 T 23-04-2016 DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 PANTHER PTHR24423 496 708 1.9E-83 T 23-04-2016 DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 Gene3D G3DSA:3.30.565.10 560 696 1.5E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 PANTHER PTHR24423 455 471 1.9E-83 T 23-04-2016 DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 SMART SM00387 587 699 2.6E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27830 ea6067452251afc1c1b2258f9486e320 1045 PANTHER PTHR24423:SF468 496 708 1.9E-83 T 23-04-2016 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 PANTHER PTHR11712 7 407 4.7E-104 T 23-04-2016 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 Pfam PF00067 Cytochrome P450 33 377 6.7E-25 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 Gene3D G3DSA:1.10.630.10 18 407 2.5E-134 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 SUPERFAMILY SSF48264 18 407 1.96E-100 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 PRINTS PR00359 B-class P450 signature 347 356 2.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 PRINTS PR00359 B-class P450 signature 326 341 2.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 PRINTS PR00359 B-class P450 signature 92 103 2.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 PRINTS PR00359 B-class P450 signature 280 291 2.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 PRINTS PR00359 B-class P450 signature 138 154 2.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 PRINTS PR00359 B-class P450 signature 193 215 2.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 PRINTS PR00359 B-class P450 signature 356 367 2.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 PRINTS PR00359 B-class P450 signature 155 170 2.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS33400 10610600f80e9b5f7a6c170519dde06c 407 PRINTS PR00359 B-class P450 signature 298 325 2.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS39340 0ef8978308af0839287df110e2a0972f 281 Pfam PF00561 alpha/beta hydrolase fold 28 134 9.5E-13 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS39340 0ef8978308af0839287df110e2a0972f 281 SUPERFAMILY SSF53474 6 280 1.91E-35 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS39340 0ef8978308af0839287df110e2a0972f 281 Gene3D G3DSA:3.40.50.1820 5 279 3.2E-34 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS39340 0ef8978308af0839287df110e2a0972f 281 PANTHER PTHR10992 8 281 5.5E-23 T 23-04-2016 DC74_RS24375 890e291d6ceb158f37c39532ae981545 271 Pfam PF00561 alpha/beta hydrolase fold 63 175 9.1E-10 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS24375 890e291d6ceb158f37c39532ae981545 271 SUPERFAMILY SSF53474 60 211 2.04E-30 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS24375 890e291d6ceb158f37c39532ae981545 271 PANTHER PTHR37946 18 181 1.3E-13 T 23-04-2016 DC74_RS24375 890e291d6ceb158f37c39532ae981545 271 Gene3D G3DSA:3.40.50.1820 59 260 4.3E-36 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS12115 e4d332d80e9e2e80e5b26602a90b876f 225 Gene3D G3DSA:3.40.50.2300 22 145 4.8E-38 T 23-04-2016 DC74_RS12115 e4d332d80e9e2e80e5b26602a90b876f 225 Gene3D G3DSA:1.10.10.10 153 208 1.1E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS12115 e4d332d80e9e2e80e5b26602a90b876f 225 Pfam PF00072 Response regulator receiver domain 25 134 5.9E-29 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS12115 e4d332d80e9e2e80e5b26602a90b876f 225 Pfam PF03861 ANTAR domain 153 205 1.7E-21 T 23-04-2016 IPR005561 ANTAR domain GO:0003723 DC74_RS12115 e4d332d80e9e2e80e5b26602a90b876f 225 SMART SM00448 23 134 1.0E-37 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS12115 e4d332d80e9e2e80e5b26602a90b876f 225 PANTHER PTHR26402 23 168 5.8E-48 T 23-04-2016 DC74_RS12115 e4d332d80e9e2e80e5b26602a90b876f 225 SMART SM01012 150 205 1.1E-24 T 23-04-2016 IPR005561 ANTAR domain GO:0003723 DC74_RS12115 e4d332d80e9e2e80e5b26602a90b876f 225 PANTHER PTHR26402:SF474 23 168 5.8E-48 T 23-04-2016 DC74_RS12115 e4d332d80e9e2e80e5b26602a90b876f 225 SUPERFAMILY SSF52172 22 205 3.42E-56 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS12115 e4d332d80e9e2e80e5b26602a90b876f 225 PIRSF PIRSF036382 15 212 6.5E-70 T 23-04-2016 IPR008327 Signal transduction response regulator, antiterminator DC74_RS04055 f4aee725fe60506e5050a3dc370b6412 254 SUPERFAMILY SSF53335 21 222 9.12E-42 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS04055 f4aee725fe60506e5050a3dc370b6412 254 Pfam PF08241 Methyltransferase domain 61 153 3.6E-24 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS04055 f4aee725fe60506e5050a3dc370b6412 254 Gene3D G3DSA:3.40.50.150 21 216 1.3E-39 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS04055 f4aee725fe60506e5050a3dc370b6412 254 PANTHER PTHR10108 23 156 1.3E-28 T 23-04-2016 DC74_RS21375 20fbdab84d3582b05ab2b28b78fbfd9f 183 Gene3D G3DSA:1.10.10.10 113 169 3.6E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21375 20fbdab84d3582b05ab2b28b78fbfd9f 183 PANTHER PTHR30173 18 169 2.6E-26 T 23-04-2016 DC74_RS21375 20fbdab84d3582b05ab2b28b78fbfd9f 183 Gene3D G3DSA:1.10.1740.10 17 89 2.9E-13 T 23-04-2016 DC74_RS21375 20fbdab84d3582b05ab2b28b78fbfd9f 183 SUPERFAMILY SSF88659 108 169 3.92E-16 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21375 20fbdab84d3582b05ab2b28b78fbfd9f 183 SUPERFAMILY SSF88946 18 107 3.18E-13 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21375 20fbdab84d3582b05ab2b28b78fbfd9f 183 Pfam PF08281 Sigma-70, region 4 114 167 8.5E-18 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21375 20fbdab84d3582b05ab2b28b78fbfd9f 183 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 17 172 7.4E-61 T 23-04-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 DC74_RS21375 20fbdab84d3582b05ab2b28b78fbfd9f 183 Pfam PF04542 Sigma-70 region 2 23 87 7.4E-8 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21375 20fbdab84d3582b05ab2b28b78fbfd9f 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 169 1.8E-20 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS36485 646946599eb145a0f282fdecd82c998d 316 SUPERFAMILY SSF50494 90 290 1.08E-17 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS36485 646946599eb145a0f282fdecd82c998d 316 Pfam PF00089 Trypsin 96 277 3.8E-8 T 23-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 DC74_RS36485 646946599eb145a0f282fdecd82c998d 316 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 117 122 - T 23-04-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 DC74_RS36485 646946599eb145a0f282fdecd82c998d 316 Gene3D G3DSA:2.40.10.10 102 195 1.8E-10 T 23-04-2016 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 Pfam PF00067 Cytochrome P450 263 362 1.6E-13 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 PANTHER PTHR24286:SF42 45 394 4.0E-52 T 23-04-2016 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 SUPERFAMILY SSF48264 18 394 3.01E-68 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 PRINTS PR00359 B-class P450 signature 138 154 3.29E-33 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 PRINTS PR00359 B-class P450 signature 285 312 3.29E-33 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 PRINTS PR00359 B-class P450 signature 334 343 3.29E-33 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 PRINTS PR00359 B-class P450 signature 313 328 3.29E-33 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 PRINTS PR00359 B-class P450 signature 343 354 3.29E-33 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 PRINTS PR00359 B-class P450 signature 155 170 3.29E-33 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 PRINTS PR00359 B-class P450 signature 267 278 3.29E-33 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 PRINTS PR00359 B-class P450 signature 191 213 3.29E-33 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 Gene3D G3DSA:1.10.630.10 19 394 1.7E-88 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS38720 91eee78e0284ed9c750b4bea9fec92bc 394 PANTHER PTHR24286 45 394 4.0E-52 T 23-04-2016 DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 Pfam PF00551 Formyl transferase 40 146 4.6E-10 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 Pfam PF02911 Formyl transferase, C-terminal domain 175 257 3.4E-6 T 23-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 SUPERFAMILY SSF52096 296 553 4.98E-34 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 SUPERFAMILY SSF53328 8 160 3.4E-24 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 SUPERFAMILY SSF50486 176 257 6.02E-9 T 23-04-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 PIRSF PIRSF006787 1 575 2.9E-237 T 23-04-2016 IPR009188 [NiFe]-hydrogenase maturation factor, HypX/HoxX type DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 Gene3D G3DSA:3.40.50.170 39 160 2.6E-21 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 PANTHER PTHR11138 314 569 4.0E-170 T 23-04-2016 DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 PANTHER PTHR11138 23 254 4.0E-170 T 23-04-2016 DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 Gene3D G3DSA:3.10.25.10 178 257 5.9E-5 T 23-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 Gene3D G3DSA:3.90.226.10 295 517 9.3E-26 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 Pfam PF00378 Enoyl-CoA hydratase/isomerase 327 527 9.9E-20 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 PANTHER PTHR11138:SF1 314 569 4.0E-170 T 23-04-2016 DC74_RS07270 16c77763f5bc52293b207e4ed7aa7884 577 PANTHER PTHR11138:SF1 23 254 4.0E-170 T 23-04-2016 DC74_RS39145 40d87847b87352915dff2a52c24a6a88 593 SMART SM00382 365 551 3.3E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS39145 40d87847b87352915dff2a52c24a6a88 593 Gene3D G3DSA:1.20.1560.10 10 326 3.3E-73 T 23-04-2016 DC74_RS39145 40d87847b87352915dff2a52c24a6a88 593 SUPERFAMILY SSF52540 329 575 4.13E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39145 40d87847b87352915dff2a52c24a6a88 593 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS39145 40d87847b87352915dff2a52c24a6a88 593 Pfam PF00005 ABC transporter 356 505 8.8E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS39145 40d87847b87352915dff2a52c24a6a88 593 PANTHER PTHR24221 8 587 9.2E-178 T 23-04-2016 DC74_RS39145 40d87847b87352915dff2a52c24a6a88 593 SUPERFAMILY SSF90123 10 326 1.57E-68 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS39145 40d87847b87352915dff2a52c24a6a88 593 Pfam PF00664 ABC transporter transmembrane region 23 290 3.6E-44 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS39145 40d87847b87352915dff2a52c24a6a88 593 Gene3D G3DSA:3.40.50.300 339 570 1.1E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21845 3c09f50dbd1b1031532905e4c2bac4cb 161 Gene3D G3DSA:1.20.1290.10 14 149 8.7E-45 T 23-04-2016 IPR029032 AhpD-like DC74_RS21845 3c09f50dbd1b1031532905e4c2bac4cb 161 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 30 80 3.6E-17 T 23-04-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS21845 3c09f50dbd1b1031532905e4c2bac4cb 161 Pfam PF02627 Carboxymuconolactone decarboxylase family 17 96 9.7E-17 T 23-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS21845 3c09f50dbd1b1031532905e4c2bac4cb 161 SUPERFAMILY SSF69118 15 146 2.59E-36 T 23-04-2016 IPR029032 AhpD-like DC74_RS06640 b15c2b6b60b4029045596c741b1d08b0 537 Gene3D G3DSA:3.20.20.140 75 474 5.9E-63 T 23-04-2016 DC74_RS06640 b15c2b6b60b4029045596c741b1d08b0 537 PANTHER PTHR11409 69 115 7.6E-36 T 23-04-2016 DC74_RS06640 b15c2b6b60b4029045596c741b1d08b0 537 PANTHER PTHR11409 133 213 7.6E-36 T 23-04-2016 DC74_RS06640 b15c2b6b60b4029045596c741b1d08b0 537 PANTHER PTHR11409 229 471 7.6E-36 T 23-04-2016 DC74_RS06640 b15c2b6b60b4029045596c741b1d08b0 537 SUPERFAMILY SSF51556 264 472 2.24E-48 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS06640 b15c2b6b60b4029045596c741b1d08b0 537 SUPERFAMILY SSF51556 70 232 2.24E-48 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS06640 b15c2b6b60b4029045596c741b1d08b0 537 Pfam PF00962 Adenosine/AMP deaminase 334 471 1.5E-21 T 23-04-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 DC74_RS16110 43fef70730b675b92315df280f1e817d 216 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 3 214 1.3E-81 T 23-04-2016 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD DC74_RS16110 43fef70730b675b92315df280f1e817d 216 SUPERFAMILY SSF161098 13 200 3.66E-40 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16110 43fef70730b675b92315df280f1e817d 216 PANTHER PTHR30614 1 216 3.7E-96 T 23-04-2016 DC74_RS16110 43fef70730b675b92315df280f1e817d 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 9.4E-31 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 DC74_RS16110 43fef70730b675b92315df280f1e817d 216 PANTHER PTHR30614:SF14 1 216 3.7E-96 T 23-04-2016 DC74_RS16110 43fef70730b675b92315df280f1e817d 216 Gene3D G3DSA:1.10.3720.10 13 214 2.2E-42 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS16110 43fef70730b675b92315df280f1e817d 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 214 7.3E-19 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS37285 61f854883ee65c03930a7c7c884a7031 216 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 3 193 35.436 T 23-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37285 61f854883ee65c03930a7c7c884a7031 216 Pfam PF00694 Aconitase C-terminal domain 8 118 1.1E-22 T 23-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37285 61f854883ee65c03930a7c7c884a7031 216 SUPERFAMILY SSF52016 9 189 9.42E-48 T 23-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel DC74_RS37285 61f854883ee65c03930a7c7c884a7031 216 Gene3D G3DSA:3.20.19.10 9 189 6.1E-37 T 23-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel DC74_RS37285 61f854883ee65c03930a7c7c884a7031 216 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 6 178 4.5E-53 T 23-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS37285 61f854883ee65c03930a7c7c884a7031 216 PANTHER PTHR11670:SF27 5 194 8.7E-79 T 23-04-2016 DC74_RS37285 61f854883ee65c03930a7c7c884a7031 216 PANTHER PTHR11670 5 194 8.7E-79 T 23-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 DC74_RS20630 fd5f25078a9d7a2a26e54957e83aed63 182 Gene3D G3DSA:1.10.260.40 25 62 2.0E-6 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS20630 fd5f25078a9d7a2a26e54957e83aed63 182 SUPERFAMILY SSF47413 22 75 5.28E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS29315 6d3736a75689ec56a411b0a1ea257125 118 PANTHER PTHR14552 4 113 4.5E-34 T 23-04-2016 DC74_RS29315 6d3736a75689ec56a411b0a1ea257125 118 Pfam PF12643 MazG-like family 34 105 8.1E-12 T 23-04-2016 IPR025984 MazG-like domain KEGG: 00240+3.6.1.12 DC74_RS29315 6d3736a75689ec56a411b0a1ea257125 118 SUPERFAMILY SSF101386 3 105 1.8E-33 T 23-04-2016 DC74_RS29315 6d3736a75689ec56a411b0a1ea257125 118 Gene3D G3DSA:1.10.287.1080 4 97 1.4E-22 T 23-04-2016 DC74_RS29315 6d3736a75689ec56a411b0a1ea257125 118 PIRSF PIRSF029826 1 113 7.6E-42 T 23-04-2016 IPR011394 NTP Pyrophosphohydrolase MazG-related, RS21-C6 DC74_RS11290 0e1fa70c75bd8a564d17c2f56bcdf970 415 Gene3D G3DSA:1.10.150.210 207 258 5.2E-24 T 23-04-2016 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|UniPathway: UPA00135 DC74_RS11290 0e1fa70c75bd8a564d17c2f56bcdf970 415 PANTHER PTHR10000 192 406 8.2E-88 T 23-04-2016 DC74_RS11290 0e1fa70c75bd8a564d17c2f56bcdf970 415 SUPERFAMILY SSF55021 19 96 7.53E-8 T 23-04-2016 DC74_RS11290 0e1fa70c75bd8a564d17c2f56bcdf970 415 Gene3D G3DSA:3.30.70.260 19 102 3.2E-14 T 23-04-2016 DC74_RS11290 0e1fa70c75bd8a564d17c2f56bcdf970 415 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 189 400 1.2E-75 T 23-04-2016 DC74_RS11290 0e1fa70c75bd8a564d17c2f56bcdf970 415 PANTHER PTHR10000:SF7 192 406 8.2E-88 T 23-04-2016 DC74_RS11290 0e1fa70c75bd8a564d17c2f56bcdf970 415 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 197 366 6.9E-29 T 23-04-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 DC74_RS11290 0e1fa70c75bd8a564d17c2f56bcdf970 415 Pfam PF13740 ACT domain 19 97 6.9E-16 T 23-04-2016 DC74_RS11290 0e1fa70c75bd8a564d17c2f56bcdf970 415 SUPERFAMILY SSF56784 196 403 1.34E-47 T 23-04-2016 IPR023214 HAD-like domain DC74_RS11290 0e1fa70c75bd8a564d17c2f56bcdf970 415 Gene3D G3DSA:3.40.50.1000 259 387 2.6E-43 T 23-04-2016 IPR023214 HAD-like domain DC74_RS11290 0e1fa70c75bd8a564d17c2f56bcdf970 415 Pfam PF12710 haloacid dehalogenase-like hydrolase 198 365 8.6E-24 T 23-04-2016 DC74_RS28840 e60f2bc83b7685c0c49ac6c4981b1039 312 SUPERFAMILY SSF53850 91 301 1.19E-36 T 23-04-2016 DC74_RS28840 e60f2bc83b7685c0c49ac6c4981b1039 312 Pfam PF03466 LysR substrate binding domain 90 298 1.3E-40 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS28840 e60f2bc83b7685c0c49ac6c4981b1039 312 Gene3D G3DSA:3.40.190.10 176 270 6.0E-23 T 23-04-2016 DC74_RS28840 e60f2bc83b7685c0c49ac6c4981b1039 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.8E-24 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS28840 e60f2bc83b7685c0c49ac6c4981b1039 312 PANTHER PTHR30346 1 295 2.8E-72 T 23-04-2016 DC74_RS28840 e60f2bc83b7685c0c49ac6c4981b1039 312 SUPERFAMILY SSF46785 1 85 1.21E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28840 e60f2bc83b7685c0c49ac6c4981b1039 312 Gene3D G3DSA:1.10.10.10 1 86 1.6E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28840 e60f2bc83b7685c0c49ac6c4981b1039 312 Gene3D G3DSA:3.40.190.10 91 175 1.4E-10 T 23-04-2016 DC74_RS28840 e60f2bc83b7685c0c49ac6c4981b1039 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.8E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS28840 e60f2bc83b7685c0c49ac6c4981b1039 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.8E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS28840 e60f2bc83b7685c0c49ac6c4981b1039 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.8E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS14325 6b7cc9949e6a49250a6fcdae0209c758 402 Pfam PF16945 Putative lactococcus lactis phage r1t holin 326 392 9.4E-12 T 23-04-2016 IPR020109 Holin, r1t-type DC74_RS14325 6b7cc9949e6a49250a6fcdae0209c758 402 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 39 179 4.3E-15 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS14325 6b7cc9949e6a49250a6fcdae0209c758 402 Gene3D G3DSA:3.40.80.10 29 197 1.6E-17 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS14325 6b7cc9949e6a49250a6fcdae0209c758 402 SUPERFAMILY SSF47090 227 301 2.04E-6 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS14325 6b7cc9949e6a49250a6fcdae0209c758 402 SMART SM00644 27 180 1.6E-19 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS14325 6b7cc9949e6a49250a6fcdae0209c758 402 SUPERFAMILY SSF55846 22 196 1.83E-24 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS00885 31106c6952d21068a595a2fd39badd84 66 PANTHER PTHR15032:SF14 3 46 1.8E-15 T 23-04-2016 DC74_RS00885 31106c6952d21068a595a2fd39badd84 66 PANTHER PTHR15032 3 46 1.8E-15 T 23-04-2016 DC74_RS00060 f8e5e8ac5d669619a68f6b9f439e8b61 109 Gene3D G3DSA:3.30.1460.30 22 102 1.4E-7 T 23-04-2016 IPR007076 TfoX, N-terminal DC74_RS00060 f8e5e8ac5d669619a68f6b9f439e8b61 109 SUPERFAMILY SSF159894 8 102 4.18E-11 T 23-04-2016 DC74_RS00060 f8e5e8ac5d669619a68f6b9f439e8b61 109 Pfam PF04993 TfoX N-terminal domain 21 101 7.8E-14 T 23-04-2016 IPR007076 TfoX, N-terminal DC74_RS18890 eb43a51c89ba484875746dce00e914b8 507 PANTHER PTHR22773:SF41 5 506 2.2E-105 T 23-04-2016 DC74_RS18890 eb43a51c89ba484875746dce00e914b8 507 Pfam PF00361 Proton-conducting membrane transporter 136 442 9.9E-51 T 23-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 DC74_RS18890 eb43a51c89ba484875746dce00e914b8 507 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 11 499 15.104 T 23-04-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 DC74_RS18890 eb43a51c89ba484875746dce00e914b8 507 PANTHER PTHR22773 5 506 2.2E-105 T 23-04-2016 DC74_RS39300 ba6bf2aba9e81f60df6b1f8f730ef5fb 370 Gene3D G3DSA:1.10.540.10 10 112 7.0E-32 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS39300 ba6bf2aba9e81f60df6b1f8f730ef5fb 370 SUPERFAMILY SSF47203 224 368 1.37E-36 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS39300 ba6bf2aba9e81f60df6b1f8f730ef5fb 370 SUPERFAMILY SSF56645 10 218 4.06E-66 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS39300 ba6bf2aba9e81f60df6b1f8f730ef5fb 370 Gene3D G3DSA:2.40.110.10 115 207 2.9E-32 T 23-04-2016 DC74_RS39300 ba6bf2aba9e81f60df6b1f8f730ef5fb 370 PANTHER PTHR10909 12 370 3.2E-105 T 23-04-2016 DC74_RS39300 ba6bf2aba9e81f60df6b1f8f730ef5fb 370 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 111 6.0E-28 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS39300 ba6bf2aba9e81f60df6b1f8f730ef5fb 370 Gene3D G3DSA:1.20.140.10 208 369 4.4E-42 T 23-04-2016 DC74_RS39300 ba6bf2aba9e81f60df6b1f8f730ef5fb 370 PANTHER PTHR10909:SF305 12 370 3.2E-105 T 23-04-2016 DC74_RS39300 ba6bf2aba9e81f60df6b1f8f730ef5fb 370 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 224 367 8.8E-36 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS39300 ba6bf2aba9e81f60df6b1f8f730ef5fb 370 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 116 206 3.1E-21 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS12775 7355474109927672b7e9ed433e30d0d3 402 PANTHER PTHR10803 1 389 1.7E-98 T 23-04-2016 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 DC74_RS12775 7355474109927672b7e9ed433e30d0d3 402 Gene3D G3DSA:3.40.50.300 192 284 1.6E-28 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12775 7355474109927672b7e9ed433e30d0d3 402 Gene3D G3DSA:3.40.50.300 4 159 1.6E-28 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12775 7355474109927672b7e9ed433e30d0d3 402 SUPERFAMILY SSF52540 2 294 6.56E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12775 7355474109927672b7e9ed433e30d0d3 402 Pfam PF02374 Anion-transporting ATPase 2 298 3.6E-32 T 23-04-2016 IPR025723 Anion-transporting ATPase-like domain DC74_RS12775 7355474109927672b7e9ed433e30d0d3 402 PANTHER PTHR10803:SF9 1 389 1.7E-98 T 23-04-2016 DC74_RS26530 5c846b51dc8df37179aea9fd84848f37 305 Pfam PF04960 Glutaminase 21 305 5.7E-109 T 23-04-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: REACT_13|Reactome: REACT_13685 DC74_RS26530 5c846b51dc8df37179aea9fd84848f37 305 SUPERFAMILY SSF56601 2 305 2.15E-105 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS26530 5c846b51dc8df37179aea9fd84848f37 305 TIGRFAM TIGR03814 Gln_ase: glutaminase A 7 305 2.9E-121 T 23-04-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: REACT_13|Reactome: REACT_13685 DC74_RS26530 5c846b51dc8df37179aea9fd84848f37 305 Hamap MF_00313 Glutaminase [glsA]. 3 305 45.171 T 23-04-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: REACT_13|Reactome: REACT_13685 DC74_RS26530 5c846b51dc8df37179aea9fd84848f37 305 Gene3D G3DSA:3.40.710.10 2 305 8.5E-116 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS26530 5c846b51dc8df37179aea9fd84848f37 305 PANTHER PTHR12544 1 305 5.8E-135 T 23-04-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: REACT_13|Reactome: REACT_13685 DC74_RS07770 15052b654c92dede96a3fc773d1d5de4 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 71 87 5.9E-14 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS07770 15052b654c92dede96a3fc773d1d5de4 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 49 69 5.9E-14 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS07770 15052b654c92dede96a3fc773d1d5de4 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 219 243 5.9E-14 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS07770 15052b654c92dede96a3fc773d1d5de4 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 91 107 5.9E-14 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS07770 15052b654c92dede96a3fc773d1d5de4 280 SUPERFAMILY SSF56655 16 274 2.36E-50 T 23-04-2016 DC74_RS07770 15052b654c92dede96a3fc773d1d5de4 280 Pfam PF00459 Inositol monophosphatase family 17 253 3.2E-38 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS07770 15052b654c92dede96a3fc773d1d5de4 280 Gene3D G3DSA:3.30.540.10 13 145 3.6E-37 T 23-04-2016 DC74_RS07770 15052b654c92dede96a3fc773d1d5de4 280 PANTHER PTHR20854 7 280 7.7E-37 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS07770 15052b654c92dede96a3fc773d1d5de4 280 Gene3D G3DSA:3.40.190.80 184 274 1.2E-11 T 23-04-2016 DC74_RS02270 8192a2dfbee34ab311d28e12cf336f17 255 Gene3D G3DSA:3.40.50.1820 2 212 2.5E-45 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02270 8192a2dfbee34ab311d28e12cf336f17 255 Pfam PF01764 Lipase (class 3) 60 192 2.7E-30 T 23-04-2016 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: REACT_14797|Reactome: REACT_604 DC74_RS02270 8192a2dfbee34ab311d28e12cf336f17 255 PANTHER PTHR21493:SF153 6 209 1.1E-38 T 23-04-2016 DC74_RS02270 8192a2dfbee34ab311d28e12cf336f17 255 PANTHER PTHR21493 6 209 1.1E-38 T 23-04-2016 DC74_RS02270 8192a2dfbee34ab311d28e12cf336f17 255 SUPERFAMILY SSF53474 2 208 4.82E-36 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08865 6847fb9bbda2ff90bc9063e472826c45 452 Gene3D G3DSA:3.40.630.10 5 193 7.5E-63 T 23-04-2016 DC74_RS08865 6847fb9bbda2ff90bc9063e472826c45 452 Gene3D G3DSA:3.40.630.10 360 450 7.5E-63 T 23-04-2016 DC74_RS08865 6847fb9bbda2ff90bc9063e472826c45 452 PANTHER PTHR11014 5 451 4.3E-123 T 23-04-2016 DC74_RS08865 6847fb9bbda2ff90bc9063e472826c45 452 PANTHER PTHR11014:SF15 5 451 4.3E-123 T 23-04-2016 DC74_RS08865 6847fb9bbda2ff90bc9063e472826c45 452 Gene3D G3DSA:3.30.70.360 199 356 4.8E-35 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS08865 6847fb9bbda2ff90bc9063e472826c45 452 Pfam PF01546 Peptidase family M20/M25/M40 86 437 5.4E-38 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS08865 6847fb9bbda2ff90bc9063e472826c45 452 SUPERFAMILY SSF53187 361 450 1.2E-55 T 23-04-2016 DC74_RS08865 6847fb9bbda2ff90bc9063e472826c45 452 SUPERFAMILY SSF53187 5 199 1.2E-55 T 23-04-2016 DC74_RS08865 6847fb9bbda2ff90bc9063e472826c45 452 Pfam PF07687 Peptidase dimerisation domain 198 347 1.1E-13 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 SUPERFAMILY SSF46946 123 188 3.24E-18 T 23-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 Gene3D G3DSA:3.20.190.10 2 102 6.5E-16 T 23-04-2016 DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 PANTHER PTHR22993:SF13 1 275 2.8E-110 T 23-04-2016 DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 Pfam PF06827 Zinc finger found in FPG and IleRS 242 272 1.4E-5 T 23-04-2016 IPR010663 Zinc finger, FPG/IleRS-type DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 124 188 2.0E-8 T 23-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 SMART SM01232 124 212 5.1E-21 T 23-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 ProSitePatterns PS01242 Zinc finger FPG-type signature. 243 271 - T 23-04-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 PANTHER PTHR22993 1 275 2.8E-110 T 23-04-2016 DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 Gene3D G3DSA:1.10.8.50 124 272 5.0E-34 T 23-04-2016 DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 80 1.2E-9 T 23-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 SUPERFAMILY SSF81624 2 125 5.89E-26 T 23-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 SMART SM00898 2 110 6.2E-22 T 23-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 DC74_RS28700 dfb4f53a39cb530d0b310b8e982075ff 277 SUPERFAMILY SSF57716 229 272 4.56E-11 T 23-04-2016 DC74_RS21615 578a7fc2910a0e2aa7834053e8b745fb 395 SUPERFAMILY SSF55469 188 251 9.03E-18 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS21615 578a7fc2910a0e2aa7834053e8b745fb 395 SUPERFAMILY SSF55469 291 394 9.03E-18 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS21615 578a7fc2910a0e2aa7834053e8b745fb 395 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 211 360 6.3E-33 T 23-04-2016 IPR020051 SagB-type dehydrogenase domain DC74_RS21615 578a7fc2910a0e2aa7834053e8b745fb 395 Gene3D G3DSA:3.40.109.10 185 355 1.5E-15 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS21615 578a7fc2910a0e2aa7834053e8b745fb 395 Pfam PF00881 Nitroreductase family 193 354 5.6E-15 T 23-04-2016 IPR029479 Nitroreductase DC74_RS11335 e33eeeddb051a1be11572bc6363d7aad 467 PANTHER PTHR11766 8 416 2.7E-125 T 23-04-2016 IPR024088 Tyrosine-tRNA ligase, bacterial-type GO:0004831 KEGG: 00970+6.1.1.1 DC74_RS11335 e33eeeddb051a1be11572bc6363d7aad 467 Gene3D G3DSA:1.10.240.10 275 359 5.0E-24 T 23-04-2016 DC74_RS11335 e33eeeddb051a1be11572bc6363d7aad 467 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 257 269 5.8E-22 T 23-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 DC74_RS11335 e33eeeddb051a1be11572bc6363d7aad 467 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 207 222 5.8E-22 T 23-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 DC74_RS11335 e33eeeddb051a1be11572bc6363d7aad 467 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 224 246 5.8E-22 T 23-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 DC74_RS11335 e33eeeddb051a1be11572bc6363d7aad 467 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 92 114 5.8E-22 T 23-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 DC74_RS11335 e33eeeddb051a1be11572bc6363d7aad 467 SUPERFAMILY SSF52374 50 364 9.12E-75 T 23-04-2016 DC74_RS11335 e33eeeddb051a1be11572bc6363d7aad 467 Pfam PF00579 tRNA synthetases class I (W and Y) 80 361 8.5E-55 T 23-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS11335 e33eeeddb051a1be11572bc6363d7aad 467 Gene3D G3DSA:3.40.50.620 68 274 2.5E-68 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS11335 e33eeeddb051a1be11572bc6363d7aad 467 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 50 419 8.8E-85 T 23-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 DC74_RS11335 e33eeeddb051a1be11572bc6363d7aad 467 PANTHER PTHR11766:SF1 8 416 2.7E-125 T 23-04-2016 DC74_RS11335 e33eeeddb051a1be11572bc6363d7aad 467 Gene3D G3DSA:3.10.290.10 360 431 5.8E-6 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 DC74_RS22515 a9623133aed3dccc9a3a59b383017274 380 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 380 40.308 T 23-04-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 DC74_RS22515 a9623133aed3dccc9a3a59b383017274 380 PANTHER PTHR11993:SF28 17 375 5.3E-177 T 23-04-2016 DC74_RS22515 a9623133aed3dccc9a3a59b383017274 380 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 53 64 - T 23-04-2016 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 DC74_RS22515 a9623133aed3dccc9a3a59b383017274 380 Gene3D G3DSA:1.10.645.10 13 368 1.3E-58 T 23-04-2016 IPR029014 NiFe hydrogenase-like DC74_RS22515 a9623133aed3dccc9a3a59b383017274 380 PANTHER PTHR11993 17 375 5.3E-177 T 23-04-2016 DC74_RS22515 a9623133aed3dccc9a3a59b383017274 380 SUPERFAMILY SSF56762 26 379 1.31E-100 T 23-04-2016 IPR029014 NiFe hydrogenase-like DC74_RS22515 a9623133aed3dccc9a3a59b383017274 380 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 131 303 3.7E-47 T 23-04-2016 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 DC74_RS22515 a9623133aed3dccc9a3a59b383017274 380 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 306 380 2.2E-20 T 23-04-2016 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 DC74_RS20805 2f352e8fde020c8a8d8acd3fcb01eb1f 343 Pfam PF01168 Alanine racemase, N-terminal domain 9 160 1.7E-14 T 23-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS20805 2f352e8fde020c8a8d8acd3fcb01eb1f 343 SUPERFAMILY SSF51419 11 176 1.31E-14 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS20805 2f352e8fde020c8a8d8acd3fcb01eb1f 343 Gene3D G3DSA:3.20.20.10 26 171 4.6E-14 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS19265 acb43e66461a58f12034bf3fc6c20c22 142 PANTHER PTHR11079 2 139 6.3E-39 T 23-04-2016 DC74_RS19265 acb43e66461a58f12034bf3fc6c20c22 142 SUPERFAMILY SSF53927 2 137 1.62E-33 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS19265 acb43e66461a58f12034bf3fc6c20c22 142 PANTHER PTHR11079:SF63 2 139 6.3E-39 T 23-04-2016 DC74_RS19265 acb43e66461a58f12034bf3fc6c20c22 142 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 93 4.3E-16 T 23-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 DC74_RS19265 acb43e66461a58f12034bf3fc6c20c22 142 Gene3D G3DSA:3.40.140.10 2 128 4.0E-31 T 23-04-2016 DC74_RS37930 2f77df191ecff523c734cafda7317437 457 SUPERFAMILY SSF52425 4 185 3.27E-37 T 23-04-2016 IPR006050 DNA photolyase, N-terminal DC74_RS37930 2f77df191ecff523c734cafda7317437 457 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 312 324 - T 23-04-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal DC74_RS37930 2f77df191ecff523c734cafda7317437 457 Pfam PF00875 DNA photolyase 5 168 7.2E-38 T 23-04-2016 IPR006050 DNA photolyase, N-terminal DC74_RS37930 2f77df191ecff523c734cafda7317437 457 Pfam PF03441 FAD binding domain of DNA photolyase 262 451 1.2E-69 T 23-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain DC74_RS37930 2f77df191ecff523c734cafda7317437 457 PANTHER PTHR11455 3 453 3.2E-140 T 23-04-2016 DC74_RS37930 2f77df191ecff523c734cafda7317437 457 Gene3D G3DSA:1.25.40.80 148 271 1.5E-30 T 23-04-2016 DC74_RS37930 2f77df191ecff523c734cafda7317437 457 Gene3D G3DSA:1.10.579.10 272 451 2.1E-67 T 23-04-2016 DC74_RS37930 2f77df191ecff523c734cafda7317437 457 SUPERFAMILY SSF48173 189 453 1.7E-90 T 23-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain DC74_RS37930 2f77df191ecff523c734cafda7317437 457 Gene3D G3DSA:3.40.50.620 2 147 9.0E-36 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS37930 2f77df191ecff523c734cafda7317437 457 PRINTS PR00147 DNA photolyase signature 371 385 7.3E-24 T 23-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 DC74_RS37930 2f77df191ecff523c734cafda7317437 457 PRINTS PR00147 DNA photolyase signature 141 157 7.3E-24 T 23-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 DC74_RS37930 2f77df191ecff523c734cafda7317437 457 PRINTS PR00147 DNA photolyase signature 312 328 7.3E-24 T 23-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 DC74_RS37930 2f77df191ecff523c734cafda7317437 457 PRINTS PR00147 DNA photolyase signature 332 350 7.3E-24 T 23-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 DC74_RS31675 e97277fbf6784a76f58ad10c81121658 355 Gene3D G3DSA:3.90.1550.10 97 351 2.7E-67 T 23-04-2016 DC74_RS31675 e97277fbf6784a76f58ad10c81121658 355 PANTHER PTHR12561:SF7 70 350 5.6E-99 T 23-04-2016 DC74_RS31675 e97277fbf6784a76f58ad10c81121658 355 PANTHER PTHR12561 70 350 5.6E-99 T 23-04-2016 DC74_RS31675 e97277fbf6784a76f58ad10c81121658 355 SUPERFAMILY SSF55681 100 351 2.06E-66 T 23-04-2016 DC74_RS31675 e97277fbf6784a76f58ad10c81121658 355 Pfam PF03099 Biotin/lipoate A/B protein ligase family 165 269 2.4E-8 T 23-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 DC74_RS02060 2bfb76042ddadfb7cb5c00800e78c542 380 PANTHER PTHR21021 117 372 1.7E-32 T 23-04-2016 DC74_RS02060 2bfb76042ddadfb7cb5c00800e78c542 380 PANTHER PTHR21021 41 46 1.7E-32 T 23-04-2016 DC74_RS02060 2bfb76042ddadfb7cb5c00800e78c542 380 SMART SM00331 142 363 9.6E-26 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS02060 2bfb76042ddadfb7cb5c00800e78c542 380 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 170 363 1.7E-37 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS28210 d20a5a76362cf542bb9a87af11293cbf 289 Pfam PF01148 Cytidylyltransferase family 28 285 2.3E-63 T 23-04-2016 DC74_RS28210 d20a5a76362cf542bb9a87af11293cbf 289 PANTHER PTHR13773 8 286 1.6E-119 T 23-04-2016 DC74_RS28210 d20a5a76362cf542bb9a87af11293cbf 289 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 243 269 - T 23-04-2016 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00557 DC74_RS28210 d20a5a76362cf542bb9a87af11293cbf 289 PANTHER PTHR13773:SF0 8 286 1.6E-119 T 23-04-2016 DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PANTHER PTHR11206 36 52 3.2E-16 T 23-04-2016 DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PANTHER PTHR11206 277 512 3.2E-16 T 23-04-2016 DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PANTHER PTHR11206 573 584 3.2E-16 T 23-04-2016 DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 Pfam PF03023 MviN-like protein 75 548 1.5E-115 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PANTHER PTHR11206:SF90 36 52 3.2E-16 T 23-04-2016 DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PANTHER PTHR11206:SF90 277 512 3.2E-16 T 23-04-2016 DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PANTHER PTHR11206:SF90 573 584 3.2E-16 T 23-04-2016 DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PRINTS PR01806 Virulence factor MviN signature 179 203 7.0E-22 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PRINTS PR01806 Virulence factor MviN signature 99 115 7.0E-22 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PRINTS PR01806 Virulence factor MviN signature 80 99 7.0E-22 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PRINTS PR01806 Virulence factor MviN signature 424 443 7.0E-22 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PRINTS PR01806 Virulence factor MviN signature 328 354 7.0E-22 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PRINTS PR01806 Virulence factor MviN signature 203 224 7.0E-22 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 PRINTS PR01806 Virulence factor MviN signature 480 497 7.0E-22 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS07210 aa07f51a2e39df7e7790f3fcd023aef6 589 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 50 580 2.2E-131 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS08920 1f8d22766d17732e7668a7124e1d95da 237 Pfam PF01553 Acyltransferase 24 149 3.5E-28 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS08920 1f8d22766d17732e7668a7124e1d95da 237 PANTHER PTHR10434 1 237 1.4E-123 T 23-04-2016 DC74_RS08920 1f8d22766d17732e7668a7124e1d95da 237 SMART SM00563 38 152 1.6E-35 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS08920 1f8d22766d17732e7668a7124e1d95da 237 Gene3D G3DSA:3.40.1130.10 29 207 2.2E-25 T 23-04-2016 DC74_RS08920 1f8d22766d17732e7668a7124e1d95da 237 PANTHER PTHR10434:SF4 1 237 1.4E-123 T 23-04-2016 DC74_RS08920 1f8d22766d17732e7668a7124e1d95da 237 SUPERFAMILY SSF69593 19 205 1.44E-38 T 23-04-2016 DC74_RS32420 f2e424310f816bca3ece158d746adca6 331 SUPERFAMILY SSF51735 17 325 7.04E-56 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32420 f2e424310f816bca3ece158d746adca6 331 PANTHER PTHR10366 17 325 3.0E-46 T 23-04-2016 DC74_RS32420 f2e424310f816bca3ece158d746adca6 331 Gene3D G3DSA:3.40.50.720 17 324 1.4E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32420 f2e424310f816bca3ece158d746adca6 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 17 257 6.3E-39 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS27385 47639a2accc68a2b4d1f91733fe7c9b1 262 Pfam PF13462 Thioredoxin 80 244 5.7E-30 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS27385 47639a2accc68a2b4d1f91733fe7c9b1 262 PANTHER PTHR13887:SF24 12 249 5.2E-53 T 23-04-2016 DC74_RS27385 47639a2accc68a2b4d1f91733fe7c9b1 262 Gene3D G3DSA:3.40.30.10 79 248 1.2E-44 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS27385 47639a2accc68a2b4d1f91733fe7c9b1 262 PANTHER PTHR13887 12 249 5.2E-53 T 23-04-2016 DC74_RS27385 47639a2accc68a2b4d1f91733fe7c9b1 262 SUPERFAMILY SSF52833 77 243 1.47E-40 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS22110 f71bfd15e592b08580b7f276abdaa7f0 311 PANTHER PTHR10000:SF10 84 250 4.4E-63 T 23-04-2016 DC74_RS22110 f71bfd15e592b08580b7f276abdaa7f0 311 Gene3D G3DSA:3.40.50.1000 94 244 1.9E-48 T 23-04-2016 IPR023214 HAD-like domain DC74_RS22110 f71bfd15e592b08580b7f276abdaa7f0 311 SUPERFAMILY SSF56784 18 229 2.21E-32 T 23-04-2016 IPR023214 HAD-like domain DC74_RS22110 f71bfd15e592b08580b7f276abdaa7f0 311 Pfam PF12710 haloacid dehalogenase-like hydrolase 23 209 2.4E-32 T 23-04-2016 DC74_RS22110 f71bfd15e592b08580b7f276abdaa7f0 311 PANTHER PTHR10000 84 250 4.4E-63 T 23-04-2016 DC74_RS22110 f71bfd15e592b08580b7f276abdaa7f0 311 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 22 210 1.9E-21 T 23-04-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 DC74_RS22110 f71bfd15e592b08580b7f276abdaa7f0 311 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 22 222 1.3E-62 T 23-04-2016 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 SMART SM01004 7 329 4.5E-214 T 23-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 197 216 2.6E-56 T 23-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 303 322 2.6E-56 T 23-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 128 142 2.6E-56 T 23-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 159 178 2.6E-56 T 23-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 248 264 2.6E-56 T 23-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 273 288 2.6E-56 T 23-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 SUPERFAMILY SSF51569 6 329 2.2E-130 T 23-04-2016 DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 248 260 - T 23-04-2016 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 PANTHER PTHR11458 7 329 3.2E-168 T 23-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 PIRSF PIRSF001415 1 330 2.8E-145 T 23-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 Pfam PF00490 Delta-aminolevulinic acid dehydratase 10 327 3.8E-137 T 23-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19430 0f330507b8699f0f6ea54a1176c20514 330 Gene3D G3DSA:3.20.20.70 7 329 5.9E-142 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS05440 6761d7631c1932f3c0834b218e84a20b 426 Pfam PF13579 Glycosyl transferase 4-like domain 33 200 1.8E-20 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain DC74_RS05440 6761d7631c1932f3c0834b218e84a20b 426 Gene3D G3DSA:3.40.50.2000 220 382 1.3E-10 T 23-04-2016 DC74_RS05440 6761d7631c1932f3c0834b218e84a20b 426 Pfam PF13692 Glycosyl transferases group 1 224 370 1.4E-24 T 23-04-2016 DC74_RS05440 6761d7631c1932f3c0834b218e84a20b 426 SUPERFAMILY SSF53756 33 406 1.88E-61 T 23-04-2016 DC74_RS05440 6761d7631c1932f3c0834b218e84a20b 426 PANTHER PTHR12526 37 423 4.8E-55 T 23-04-2016 DC74_RS30000 4425018e7a38332cc1f0bb964297c9f9 403 PANTHER PTHR11926 3 158 1.4E-54 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS30000 4425018e7a38332cc1f0bb964297c9f9 403 PANTHER PTHR11926 186 399 1.4E-54 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS30000 4425018e7a38332cc1f0bb964297c9f9 403 Gene3D G3DSA:3.40.50.2000 9 240 8.1E-18 T 23-04-2016 DC74_RS30000 4425018e7a38332cc1f0bb964297c9f9 403 ProSitePatterns PS00375 UDP-glycosyltransferases signature. 292 333 - T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS30000 4425018e7a38332cc1f0bb964297c9f9 403 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 236 370 3.6E-23 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS30000 4425018e7a38332cc1f0bb964297c9f9 403 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 11 400 2.9E-132 T 23-04-2016 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 DC74_RS30000 4425018e7a38332cc1f0bb964297c9f9 403 SUPERFAMILY SSF53756 7 398 3.4E-79 T 23-04-2016 DC74_RS30000 4425018e7a38332cc1f0bb964297c9f9 403 Gene3D G3DSA:3.40.50.2000 241 383 4.1E-35 T 23-04-2016 DC74_RS30000 4425018e7a38332cc1f0bb964297c9f9 403 PANTHER PTHR11926:SF16 3 158 1.4E-54 T 23-04-2016 DC74_RS30000 4425018e7a38332cc1f0bb964297c9f9 403 PANTHER PTHR11926:SF16 186 399 1.4E-54 T 23-04-2016 DC74_RS04925 f1ede981f4205191e4be6981609eff92 420 PANTHER PTHR30365 1 321 6.0E-60 T 23-04-2016 DC74_RS04925 f1ede981f4205191e4be6981609eff92 420 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 318 1.7E-67 T 23-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 DC74_RS04925 f1ede981f4205191e4be6981609eff92 420 PANTHER PTHR30365:SF4 1 321 6.0E-60 T 23-04-2016 DC74_RS34390 730a1d78453ef7812ed4dcee4f95e53c 546 PANTHER PTHR10357:SF11 441 494 9.3E-146 T 23-04-2016 DC74_RS34390 730a1d78453ef7812ed4dcee4f95e53c 546 PANTHER PTHR10357:SF11 1 406 9.3E-146 T 23-04-2016 DC74_RS34390 730a1d78453ef7812ed4dcee4f95e53c 546 SUPERFAMILY SSF51445 1 461 1.27E-112 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS34390 730a1d78453ef7812ed4dcee4f95e53c 546 SMART SM00642 3 401 6.9E-114 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS34390 730a1d78453ef7812ed4dcee4f95e53c 546 Pfam PF11941 Domain of unknown function (DUF3459) 448 523 3.5E-7 T 23-04-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) DC74_RS34390 730a1d78453ef7812ed4dcee4f95e53c 546 Gene3D G3DSA:3.90.400.10 95 172 3.5E-27 T 23-04-2016 DC74_RS34390 730a1d78453ef7812ed4dcee4f95e53c 546 Pfam PF00128 Alpha amylase, catalytic domain 18 375 1.5E-68 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS34390 730a1d78453ef7812ed4dcee4f95e53c 546 Gene3D G3DSA:3.20.20.80 173 461 8.8E-91 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS34390 730a1d78453ef7812ed4dcee4f95e53c 546 Gene3D G3DSA:3.20.20.80 1 94 8.8E-91 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS34390 730a1d78453ef7812ed4dcee4f95e53c 546 PANTHER PTHR10357 441 494 9.3E-146 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS34390 730a1d78453ef7812ed4dcee4f95e53c 546 PANTHER PTHR10357 1 406 9.3E-146 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS14245 6459351f1d71078b536495fac80e3aeb 208 SUPERFAMILY SSF53098 24 180 5.61E-5 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS34325 b39dc1fe238cec2faa6d85c9eca04084 117 Pfam PF12680 SnoaL-like domain 11 105 1.6E-6 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS34325 b39dc1fe238cec2faa6d85c9eca04084 117 Gene3D G3DSA:3.10.450.50 1 111 2.2E-10 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS34325 b39dc1fe238cec2faa6d85c9eca04084 117 SUPERFAMILY SSF54427 1 110 3.32E-14 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS34495 2aadb8065441ebd4b94f663314100ce6 479 Pfam PF07690 Major Facilitator Superfamily 29 426 4.2E-39 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS34495 2aadb8065441ebd4b94f663314100ce6 479 PANTHER PTHR23501 17 470 2.5E-65 T 23-04-2016 DC74_RS34495 2aadb8065441ebd4b94f663314100ce6 479 Gene3D G3DSA:1.20.1250.20 274 474 4.3E-13 T 23-04-2016 DC74_RS34495 2aadb8065441ebd4b94f663314100ce6 479 Gene3D G3DSA:1.20.1250.20 25 205 5.9E-29 T 23-04-2016 DC74_RS34495 2aadb8065441ebd4b94f663314100ce6 479 SUPERFAMILY SSF103473 25 213 7.72E-51 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS34495 2aadb8065441ebd4b94f663314100ce6 479 SUPERFAMILY SSF103473 260 474 7.72E-51 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05495 009fe6b8e2ffd72a8cfb38c9d1ac942e 215 SUPERFAMILY SSF102588 11 209 2.62E-31 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS05495 009fe6b8e2ffd72a8cfb38c9d1ac942e 215 Pfam PF02585 GlcNAc-PI de-N-acetylase 14 128 2.1E-11 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS05495 009fe6b8e2ffd72a8cfb38c9d1ac942e 215 Gene3D G3DSA:3.40.50.10320 11 209 2.8E-34 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS19195 bf5e4f605ddeed09344dfee4fbb0fce2 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 2.6E-14 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS19195 bf5e4f605ddeed09344dfee4fbb0fce2 225 PANTHER PTHR30328 7 223 5.7E-61 T 23-04-2016 DC74_RS19195 bf5e4f605ddeed09344dfee4fbb0fce2 225 SUPERFAMILY SSF46689 6 82 9.23E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS19195 bf5e4f605ddeed09344dfee4fbb0fce2 225 Gene3D G3DSA:1.10.357.10 4 215 3.4E-40 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS19195 bf5e4f605ddeed09344dfee4fbb0fce2 225 PANTHER PTHR30328:SF28 7 223 5.7E-61 T 23-04-2016 DC74_RS19195 bf5e4f605ddeed09344dfee4fbb0fce2 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 4.7E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS19195 bf5e4f605ddeed09344dfee4fbb0fce2 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 4.7E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 PANTHER PTHR24423 24 33 2.9E-65 T 23-04-2016 DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 PANTHER PTHR24423 129 369 2.9E-65 T 23-04-2016 DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 Gene3D G3DSA:1.10.287.130 142 210 3.3E-18 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 SMART SM00388 150 214 3.3E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 260 368 2.5E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 SUPERFAMILY SSF47384 137 214 2.55E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 Gene3D G3DSA:3.30.565.10 217 369 6.9E-36 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 3.4E-10 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 310 3.4E-10 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 348 3.4E-10 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 Pfam PF00512 His Kinase A (phospho-acceptor) domain 150 214 7.7E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 SMART SM00387 259 369 7.0E-26 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS39215 0ee398799201b05c0b59f4e791914ae1 370 SUPERFAMILY SSF55874 204 367 1.06E-35 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17215 5257d3cf3365bc03bb45314ca530b4c8 451 PANTHER PTHR11271 23 450 4.8E-158 T 23-04-2016 DC74_RS17215 5257d3cf3365bc03bb45314ca530b4c8 451 Pfam PF01979 Amidohydrolase family 58 424 1.2E-43 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS17215 5257d3cf3365bc03bb45314ca530b4c8 451 Gene3D G3DSA:2.30.40.10 26 61 5.7E-4 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS17215 5257d3cf3365bc03bb45314ca530b4c8 451 Gene3D G3DSA:2.30.40.10 385 428 5.7E-4 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS17215 5257d3cf3365bc03bb45314ca530b4c8 451 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 10 450 2.9E-167 T 23-04-2016 IPR010252 Formiminoglutamate deiminase DC74_RS17215 5257d3cf3365bc03bb45314ca530b4c8 451 SUPERFAMILY SSF51556 59 374 9.83E-74 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS17215 5257d3cf3365bc03bb45314ca530b4c8 451 SUPERFAMILY SSF51338 332 450 5.65E-13 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS17215 5257d3cf3365bc03bb45314ca530b4c8 451 Gene3D G3DSA:3.20.20.140 62 384 7.1E-84 T 23-04-2016 DC74_RS17215 5257d3cf3365bc03bb45314ca530b4c8 451 PANTHER PTHR11271:SF4 23 450 4.8E-158 T 23-04-2016 IPR010252 Formiminoglutamate deiminase DC74_RS27085 bcb0d15790dbb1563bb8773c9d8c20f1 282 PIRSF PIRSF000105 1 282 2.9E-90 T 23-04-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 DC74_RS27085 bcb0d15790dbb1563bb8773c9d8c20f1 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 23-04-2016 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS27085 bcb0d15790dbb1563bb8773c9d8c20f1 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 281 3.7E-30 T 23-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS27085 bcb0d15790dbb1563bb8773c9d8c20f1 282 PANTHER PTHR23309 3 280 5.1E-138 T 23-04-2016 DC74_RS27085 bcb0d15790dbb1563bb8773c9d8c20f1 282 Gene3D G3DSA:3.40.50.720 3 187 1.3E-64 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27085 bcb0d15790dbb1563bb8773c9d8c20f1 282 SUPERFAMILY SSF48179 186 281 4.93E-27 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS27085 bcb0d15790dbb1563bb8773c9d8c20f1 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 2.8E-69 T 23-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS27085 bcb0d15790dbb1563bb8773c9d8c20f1 282 SUPERFAMILY SSF51735 3 182 3.38E-62 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27085 bcb0d15790dbb1563bb8773c9d8c20f1 282 Gene3D G3DSA:1.10.1040.10 188 281 1.1E-29 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS38060 bd54cf411b6e80c7170d9c5734edf11f 164 Pfam PF00293 NUDIX domain 22 144 2.7E-16 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS38060 bd54cf411b6e80c7170d9c5734edf11f 164 Gene3D G3DSA:3.90.79.10 12 154 9.7E-25 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS38060 bd54cf411b6e80c7170d9c5734edf11f 164 PANTHER PTHR22769 8 152 4.1E-18 T 23-04-2016 DC74_RS38060 bd54cf411b6e80c7170d9c5734edf11f 164 SUPERFAMILY SSF55811 5 154 2.17E-26 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS10770 b2a94c09273420d2be3c31597e558f5a 321 Pfam PF02678 Pirin 45 139 3.8E-25 T 23-04-2016 IPR003829 Pirin, N-terminal domain DC74_RS10770 b2a94c09273420d2be3c31597e558f5a 321 Pfam PF05726 Pirin C-terminal cupin domain 192 288 7.4E-19 T 23-04-2016 IPR008778 Pirin, C-terminal domain DC74_RS10770 b2a94c09273420d2be3c31597e558f5a 321 PANTHER PTHR13903 1 309 6.4E-136 T 23-04-2016 IPR012093 Pirin DC74_RS10770 b2a94c09273420d2be3c31597e558f5a 321 PIRSF PIRSF006232 18 301 1.9E-76 T 23-04-2016 IPR012093 Pirin DC74_RS10770 b2a94c09273420d2be3c31597e558f5a 321 SUPERFAMILY SSF51182 34 301 4.27E-67 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS10770 b2a94c09273420d2be3c31597e558f5a 321 Gene3D G3DSA:2.60.120.10 29 265 1.6E-58 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS10770 b2a94c09273420d2be3c31597e558f5a 321 PANTHER PTHR13903:SF4 1 309 6.4E-136 T 23-04-2016 DC74_RS26275 406433ab4e6e654c23898bdba5cf8151 937 PANTHER PTHR39344 1 930 0.0 T 23-04-2016 DC74_RS26275 406433ab4e6e654c23898bdba5cf8151 937 Pfam PF03699 Uncharacterised protein family (UPF0182) 3 789 9.1E-284 T 23-04-2016 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 DC74_RS26275 406433ab4e6e654c23898bdba5cf8151 937 Hamap MF_01600 UPF0182 protein . 1 867 18.26 T 23-04-2016 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 DC74_RS37660 7975a4ed131f8c15f98a650799682f73 127 SUPERFAMILY SSF48498 2 122 4.0E-29 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS37660 7975a4ed131f8c15f98a650799682f73 127 Gene3D G3DSA:1.10.357.10 2 107 3.2E-10 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS35475 ee3e433342be00cfaf31d4796bab3b16 232 SUPERFAMILY SSF81301 10 107 6.13E-9 T 23-04-2016 DC74_RS35475 ee3e433342be00cfaf31d4796bab3b16 232 Gene3D G3DSA:3.30.460.10 13 113 1.5E-8 T 23-04-2016 DC74_RS35475 ee3e433342be00cfaf31d4796bab3b16 232 Pfam PF01909 Nucleotidyltransferase domain 10 78 6.1E-5 T 23-04-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DC74_RS27930 165ad82187f33e87d92bf89cd62d331a 248 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 5 200 1.3E-49 T 23-04-2016 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198|UniPathway: UPA00071 DC74_RS27930 165ad82187f33e87d92bf89cd62d331a 248 SUPERFAMILY SSF53448 5 203 6.75E-30 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS27930 165ad82187f33e87d92bf89cd62d331a 248 Pfam PF01983 Guanylyl transferase CofC like 5 198 3.5E-10 T 23-04-2016 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198|UniPathway: UPA00071 DC74_RS27930 165ad82187f33e87d92bf89cd62d331a 248 PANTHER PTHR40392 2 226 1.5E-48 T 23-04-2016 DC74_RS27930 165ad82187f33e87d92bf89cd62d331a 248 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 3 207 22.253 T 23-04-2016 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198|UniPathway: UPA00071 DC74_RS27930 165ad82187f33e87d92bf89cd62d331a 248 Gene3D G3DSA:3.90.550.10 5 167 3.5E-23 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS27930 165ad82187f33e87d92bf89cd62d331a 248 PANTHER PTHR40392:SF1 2 226 1.5E-48 T 23-04-2016 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 SUPERFAMILY SSF52540 348 613 6.48E-31 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 Gene3D G3DSA:1.25.40.10 176 256 4.3E-12 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 Gene3D G3DSA:1.25.40.10 18 52 4.3E-12 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 PANTHER PTHR13779:SF20 62 610 3.3E-203 T 23-04-2016 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 SUPERFAMILY SSF48452 175 245 4.43E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 SUPERFAMILY SSF48452 11 51 4.43E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 SMART SM00382 384 525 2.0E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 389 522 5.6E-14 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 PANTHER PTHR13779 62 610 3.3E-203 T 23-04-2016 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 Gene3D G3DSA:3.40.50.300 347 522 3.0E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 PRINTS PR00819 CbxX/CfqX superfamily signature 347 361 2.5E-49 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 PRINTS PR00819 CbxX/CfqX superfamily signature 387 402 2.5E-49 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 PRINTS PR00819 CbxX/CfqX superfamily signature 570 582 2.5E-49 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 PRINTS PR00819 CbxX/CfqX superfamily signature 510 529 2.5E-49 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 PRINTS PR00819 CbxX/CfqX superfamily signature 439 458 2.5E-49 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 PRINTS PR00819 CbxX/CfqX superfamily signature 425 439 2.5E-49 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 PRINTS PR00819 CbxX/CfqX superfamily signature 472 484 2.5E-49 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS09180 dca46b80386a9f1cefc2c0bdddef81a9 633 PRINTS PR00819 CbxX/CfqX superfamily signature 493 510 2.5E-49 T 23-04-2016 IPR000641 CbxX/CfqX GO:0005524 DC74_RS07955 a34a4ff1975a88a08f3cea403d88c9f1 172 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 33 119 1.2E-18 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS07955 a34a4ff1975a88a08f3cea403d88c9f1 172 Gene3D G3DSA:2.30.110.10 28 169 7.8E-38 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS07955 a34a4ff1975a88a08f3cea403d88c9f1 172 PANTHER PTHR35176 21 169 3.5E-45 T 23-04-2016 DC74_RS07955 a34a4ff1975a88a08f3cea403d88c9f1 172 PANTHER PTHR35176:SF3 21 169 3.5E-45 T 23-04-2016 DC74_RS07955 a34a4ff1975a88a08f3cea403d88c9f1 172 SUPERFAMILY SSF50475 25 168 1.79E-31 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS15905 f34c1ed208da01be170d40b8d1197115 543 PANTHER PTHR22855:SF35 1 543 0.0 T 23-04-2016 DC74_RS15905 f34c1ed208da01be170d40b8d1197115 543 SUPERFAMILY SSF52096 240 520 2.66E-87 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS15905 f34c1ed208da01be170d40b8d1197115 543 SUPERFAMILY SSF52096 28 272 3.77E-72 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS15905 f34c1ed208da01be170d40b8d1197115 543 PANTHER PTHR22855 1 543 0.0 T 23-04-2016 DC74_RS15905 f34c1ed208da01be170d40b8d1197115 543 Pfam PF01039 Carboxyl transferase domain 51 527 4.4E-148 T 23-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 DC74_RS15905 f34c1ed208da01be170d40b8d1197115 543 Gene3D G3DSA:3.90.226.10 283 530 1.8E-94 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS15905 f34c1ed208da01be170d40b8d1197115 543 Gene3D G3DSA:3.90.226.10 33 270 5.0E-79 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS32450 53beeeefd7c6b720e828e6117837bbed 207 Gene3D G3DSA:3.40.50.300 24 197 2.1E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32450 53beeeefd7c6b720e828e6117837bbed 207 PRINTS PR00449 Transforming protein P21 ras signature 26 47 1.6E-6 T 23-04-2016 DC74_RS32450 53beeeefd7c6b720e828e6117837bbed 207 PRINTS PR00449 Transforming protein P21 ras signature 84 106 1.6E-6 T 23-04-2016 DC74_RS32450 53beeeefd7c6b720e828e6117837bbed 207 PRINTS PR00449 Transforming protein P21 ras signature 174 196 1.6E-6 T 23-04-2016 DC74_RS32450 53beeeefd7c6b720e828e6117837bbed 207 SUPERFAMILY SSF52540 24 197 3.21E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32450 53beeeefd7c6b720e828e6117837bbed 207 PANTHER PTHR11711:SF117 26 196 2.2E-58 T 23-04-2016 DC74_RS32450 53beeeefd7c6b720e828e6117837bbed 207 PANTHER PTHR11711 26 196 2.2E-58 T 23-04-2016 DC74_RS32450 53beeeefd7c6b720e828e6117837bbed 207 Pfam PF03029 Conserved hypothetical ATP binding protein 30 197 4.0E-25 T 23-04-2016 IPR004130 GPN-loop GTPase DC74_RS13150 0881255ac6c6ab36e09f6b0effb79b79 531 Gene3D G3DSA:3.40.50.980 17 186 8.0E-23 T 23-04-2016 DC74_RS13150 0881255ac6c6ab36e09f6b0effb79b79 531 SUPERFAMILY SSF56801 9 525 8.63E-119 T 23-04-2016 DC74_RS13150 0881255ac6c6ab36e09f6b0effb79b79 531 PANTHER PTHR24096 16 524 8.0E-147 T 23-04-2016 DC74_RS13150 0881255ac6c6ab36e09f6b0effb79b79 531 Pfam PF00501 AMP-binding enzyme 25 428 1.3E-80 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS13150 0881255ac6c6ab36e09f6b0effb79b79 531 Gene3D G3DSA:3.30.300.30 423 524 1.8E-21 T 23-04-2016 DC74_RS13150 0881255ac6c6ab36e09f6b0effb79b79 531 Gene3D G3DSA:2.30.38.10 347 421 2.6E-26 T 23-04-2016 DC74_RS13150 0881255ac6c6ab36e09f6b0effb79b79 531 Gene3D G3DSA:3.40.50.980 187 338 1.4E-28 T 23-04-2016 DC74_RS13150 0881255ac6c6ab36e09f6b0effb79b79 531 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS13150 0881255ac6c6ab36e09f6b0effb79b79 531 PANTHER PTHR24096:SF232 16 524 8.0E-147 T 23-04-2016 DC74_RS13150 0881255ac6c6ab36e09f6b0effb79b79 531 Pfam PF13193 AMP-binding enzyme C-terminal domain 437 515 1.2E-13 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS24930 3a671cea77a2ff5d7fbea1fc8c27d821 378 PANTHER PTHR32196:SF30 1 357 8.5E-92 T 23-04-2016 DC74_RS24930 3a671cea77a2ff5d7fbea1fc8c27d821 378 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 333 3.3E-39 T 23-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 DC74_RS24930 3a671cea77a2ff5d7fbea1fc8c27d821 378 PANTHER PTHR32196 1 357 8.5E-92 T 23-04-2016 DC74_RS31755 a8016ea96b3a268a616bb7d5c36688c0 401 PANTHER PTHR10909 10 398 2.1E-153 T 23-04-2016 DC74_RS31755 a8016ea96b3a268a616bb7d5c36688c0 401 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 230 2.6E-20 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS31755 a8016ea96b3a268a616bb7d5c36688c0 401 Gene3D G3DSA:1.10.540.10 9 123 3.9E-37 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS31755 a8016ea96b3a268a616bb7d5c36688c0 401 Gene3D G3DSA:2.40.110.10 125 232 2.3E-32 T 23-04-2016 DC74_RS31755 a8016ea96b3a268a616bb7d5c36688c0 401 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 122 1.4E-31 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS31755 a8016ea96b3a268a616bb7d5c36688c0 401 PIRSF PIRSF016578 6 396 1.4E-16 T 23-04-2016 DC74_RS31755 a8016ea96b3a268a616bb7d5c36688c0 401 SUPERFAMILY SSF56645 9 253 3.53E-70 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS31755 a8016ea96b3a268a616bb7d5c36688c0 401 PANTHER PTHR10909:SF10 10 398 2.1E-153 T 23-04-2016 DC74_RS31755 a8016ea96b3a268a616bb7d5c36688c0 401 SUPERFAMILY SSF47203 243 397 5.96E-54 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS31755 a8016ea96b3a268a616bb7d5c36688c0 401 Gene3D G3DSA:1.20.140.10 233 398 3.9E-60 T 23-04-2016 DC74_RS31755 a8016ea96b3a268a616bb7d5c36688c0 401 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 394 1.7E-46 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 PANTHER PTHR24286 54 410 5.3E-100 T 23-04-2016 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 SUPERFAMILY SSF48264 12 409 1.7E-84 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 PRINTS PR00359 B-class P450 signature 207 229 1.2E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 PRINTS PR00359 B-class P450 signature 302 329 1.2E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 PRINTS PR00359 B-class P450 signature 102 113 1.2E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 PRINTS PR00359 B-class P450 signature 361 372 1.2E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 PRINTS PR00359 B-class P450 signature 165 180 1.2E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 PRINTS PR00359 B-class P450 signature 352 361 1.2E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 PRINTS PR00359 B-class P450 signature 285 296 1.2E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 PRINTS PR00359 B-class P450 signature 148 164 1.2E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 PRINTS PR00359 B-class P450 signature 330 345 1.2E-47 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 PANTHER PTHR24286:SF42 54 410 5.3E-100 T 23-04-2016 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 Pfam PF00067 Cytochrome P450 288 376 5.5E-17 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS13700 6294e9c36caedd80bb9d8970aa50e406 410 Gene3D G3DSA:1.10.630.10 7 409 4.1E-116 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS22000 900833854686d33acdf201e805f775a1 308 PANTHER PTHR31302:SF6 149 308 3.8E-53 T 23-04-2016 DC74_RS22000 900833854686d33acdf201e805f775a1 308 PANTHER PTHR31302:SF6 1 119 3.8E-53 T 23-04-2016 DC74_RS22000 900833854686d33acdf201e805f775a1 308 Pfam PF00149 Calcineurin-like phosphoesterase 47 239 9.7E-6 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS22000 900833854686d33acdf201e805f775a1 308 SUPERFAMILY SSF56300 41 304 2.48E-25 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS22000 900833854686d33acdf201e805f775a1 308 PANTHER PTHR31302 149 308 3.8E-53 T 23-04-2016 DC74_RS22000 900833854686d33acdf201e805f775a1 308 PANTHER PTHR31302 1 119 3.8E-53 T 23-04-2016 DC74_RS22000 900833854686d33acdf201e805f775a1 308 Gene3D G3DSA:3.60.21.10 46 116 4.1E-13 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS22000 900833854686d33acdf201e805f775a1 308 Gene3D G3DSA:3.60.21.10 149 253 4.1E-13 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS09105 eaef71628e946279634e2fd3ff56cc8f 419 Gene3D G3DSA:3.30.470.20 100 326 4.7E-30 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS09105 eaef71628e946279634e2fd3ff56cc8f 419 PANTHER PTHR23132 193 291 5.1E-15 T 23-04-2016 DC74_RS09105 eaef71628e946279634e2fd3ff56cc8f 419 PANTHER PTHR23132 100 177 5.1E-15 T 23-04-2016 DC74_RS09105 eaef71628e946279634e2fd3ff56cc8f 419 SUPERFAMILY SSF56059 104 327 4.6E-37 T 23-04-2016 DC74_RS09105 eaef71628e946279634e2fd3ff56cc8f 419 Pfam PF13535 ATP-grasp domain 141 300 1.1E-21 T 23-04-2016 DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.7E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.7E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.7E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.7E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.7E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.7E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 SUPERFAMILY SSF51735 6 253 3.06E-76 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PANTHER PTHR24322 11 144 3.6E-59 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PANTHER PTHR24322 160 191 3.6E-59 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 251 2.8E-59 T 23-04-2016 DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PANTHER PTHR24322:SF390 11 144 3.6E-59 T 23-04-2016 DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PANTHER PTHR24322:SF390 160 191 3.6E-59 T 23-04-2016 DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 Gene3D G3DSA:3.40.50.720 1 253 1.3E-80 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.9E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.9E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.9E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS35815 6182f3f8c8fb94338c6b5d8e146ce1d1 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS12700 dc874458a2376d0ee51811030d40bad4 206 Pfam PF00174 Oxidoreductase molybdopterin binding domain 29 177 9.4E-26 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS12700 dc874458a2376d0ee51811030d40bad4 206 PANTHER PTHR19372 4 200 1.2E-60 T 23-04-2016 DC74_RS12700 dc874458a2376d0ee51811030d40bad4 206 Gene3D G3DSA:3.90.420.10 8 195 1.1E-43 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS12700 dc874458a2376d0ee51811030d40bad4 206 SUPERFAMILY SSF56524 12 198 1.7E-51 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS16265 0456aa63ca2e1790f2864359caa96442 341 SUPERFAMILY SSF52540 30 248 5.51E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16265 0456aa63ca2e1790f2864359caa96442 341 PANTHER PTHR24220:SF193 14 325 2.8E-98 T 23-04-2016 DC74_RS16265 0456aa63ca2e1790f2864359caa96442 341 PANTHER PTHR24220 14 325 2.8E-98 T 23-04-2016 DC74_RS16265 0456aa63ca2e1790f2864359caa96442 341 Gene3D G3DSA:3.40.50.300 6 248 2.4E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16265 0456aa63ca2e1790f2864359caa96442 341 Pfam PF00005 ABC transporter 42 185 1.0E-23 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS16265 0456aa63ca2e1790f2864359caa96442 341 SMART SM00382 50 244 2.3E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS05450 025173a1209668404b9c938d0c4795a9 517 Pfam PF02706 Chain length determinant protein 16 140 1.1E-10 T 23-04-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 DC74_RS15935 8cf118715881e336505479a38f6a607c 609 Pfam PF13522 Glutamine amidotransferase domain 68 194 3.2E-21 T 23-04-2016 DC74_RS15935 8cf118715881e336505479a38f6a607c 609 PANTHER PTHR10937:SF0 1 609 4.4E-292 T 23-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 DC74_RS15935 8cf118715881e336505479a38f6a607c 609 Pfam PF01380 SIS domain 299 421 2.2E-28 T 23-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 DC74_RS15935 8cf118715881e336505479a38f6a607c 609 Pfam PF01380 SIS domain 466 590 1.2E-20 T 23-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 DC74_RS15935 8cf118715881e336505479a38f6a607c 609 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 609 1.0E-219 T 23-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 DC74_RS15935 8cf118715881e336505479a38f6a607c 609 Gene3D G3DSA:3.40.50.10490 249 446 7.5E-68 T 23-04-2016 DC74_RS15935 8cf118715881e336505479a38f6a607c 609 SUPERFAMILY SSF56235 2 235 1.63E-64 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS15935 8cf118715881e336505479a38f6a607c 609 SUPERFAMILY SSF53697 249 609 8.91E-99 T 23-04-2016 DC74_RS15935 8cf118715881e336505479a38f6a607c 609 Gene3D G3DSA:3.60.20.10 2 236 3.1E-72 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS15935 8cf118715881e336505479a38f6a607c 609 Gene3D G3DSA:3.40.50.10490 447 609 8.5E-57 T 23-04-2016 DC74_RS15935 8cf118715881e336505479a38f6a607c 609 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 609 37.279 T 23-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 DC74_RS15935 8cf118715881e336505479a38f6a607c 609 PANTHER PTHR10937 1 609 4.4E-292 T 23-04-2016 DC74_RS12910 7c7dc37d2a0a02eb75a8b089923294e1 416 Pfam PF03734 L,D-transpeptidase catalytic domain 237 358 8.8E-15 T 23-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 DC74_RS12910 7c7dc37d2a0a02eb75a8b089923294e1 416 PANTHER PTHR30582 16 402 6.8E-107 T 23-04-2016 DC74_RS12910 7c7dc37d2a0a02eb75a8b089923294e1 416 SUPERFAMILY SSF141523 233 358 1.83E-27 T 23-04-2016 DC74_RS12910 7c7dc37d2a0a02eb75a8b089923294e1 416 Gene3D G3DSA:2.40.440.10 236 360 1.4E-18 T 23-04-2016 DC74_RS12910 7c7dc37d2a0a02eb75a8b089923294e1 416 PANTHER PTHR30582:SF2 16 402 6.8E-107 T 23-04-2016 DC74_RS01080 9ffae801bc596dcda8896a3631c86a9c 397 PIRSF PIRSF000524 11 397 8.4E-126 T 23-04-2016 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 DC74_RS01080 9ffae801bc596dcda8896a3631c86a9c 397 Pfam PF00266 Aminotransferase class-V 18 339 2.1E-34 T 23-04-2016 IPR000192 Aminotransferase class V domain DC74_RS01080 9ffae801bc596dcda8896a3631c86a9c 397 PANTHER PTHR21152:SF21 4 384 9.9E-132 T 23-04-2016 DC74_RS01080 9ffae801bc596dcda8896a3631c86a9c 397 Gene3D G3DSA:3.40.640.10 28 270 2.1E-56 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS01080 9ffae801bc596dcda8896a3631c86a9c 397 PANTHER PTHR21152 4 384 9.9E-132 T 23-04-2016 DC74_RS01080 9ffae801bc596dcda8896a3631c86a9c 397 Gene3D G3DSA:3.90.1150.10 271 380 1.7E-32 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS01080 9ffae801bc596dcda8896a3631c86a9c 397 SUPERFAMILY SSF53383 15 379 1.32E-102 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS03520 59694bba5d6ca661dbb1cf331a32824f 226 PANTHER PTHR30055:SF43 7 208 1.9E-45 T 23-04-2016 DC74_RS03520 59694bba5d6ca661dbb1cf331a32824f 226 SUPERFAMILY SSF46689 14 91 1.9E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03520 59694bba5d6ca661dbb1cf331a32824f 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 3.8E-14 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03520 59694bba5d6ca661dbb1cf331a32824f 226 SUPERFAMILY SSF48498 88 194 1.07E-20 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS03520 59694bba5d6ca661dbb1cf331a32824f 226 PANTHER PTHR30055 7 208 1.9E-45 T 23-04-2016 DC74_RS03520 59694bba5d6ca661dbb1cf331a32824f 226 Gene3D G3DSA:1.10.357.10 13 201 2.2E-45 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS03520 59694bba5d6ca661dbb1cf331a32824f 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 4.8E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03520 59694bba5d6ca661dbb1cf331a32824f 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 4.8E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS07175 0df10da179e6d15d51b35034f06f8764 397 Gene3D G3DSA:3.40.640.10 63 279 1.0E-87 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS07175 0df10da179e6d15d51b35034f06f8764 397 Gene3D G3DSA:3.90.1150.10 280 390 1.2E-30 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS07175 0df10da179e6d15d51b35034f06f8764 397 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 396 54.019 T 23-04-2016 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|UniPathway: UPA00046 DC74_RS07175 0df10da179e6d15d51b35034f06f8764 397 Pfam PF00155 Aminotransferase class I and II 46 388 2.5E-70 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS07175 0df10da179e6d15d51b35034f06f8764 397 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 6 392 7.8E-192 T 23-04-2016 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|UniPathway: UPA00046 DC74_RS07175 0df10da179e6d15d51b35034f06f8764 397 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 242 251 - T 23-04-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 DC74_RS07175 0df10da179e6d15d51b35034f06f8764 397 PANTHER PTHR13693 1 396 3.1E-248 T 23-04-2016 DC74_RS07175 0df10da179e6d15d51b35034f06f8764 397 SUPERFAMILY SSF53383 7 392 6.38E-117 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS07175 0df10da179e6d15d51b35034f06f8764 397 PANTHER PTHR13693:SF60 1 396 3.1E-248 T 23-04-2016 DC74_RS38450 d97dfa1f4f7fcda73d63364b19fdbaa2 293 Pfam PF13365 Trypsin-like peptidase domain 72 226 5.5E-11 T 23-04-2016 DC74_RS38450 d97dfa1f4f7fcda73d63364b19fdbaa2 293 Gene3D G3DSA:2.40.10.10 143 235 4.8E-6 T 23-04-2016 DC74_RS38450 d97dfa1f4f7fcda73d63364b19fdbaa2 293 SUPERFAMILY SSF50494 44 241 3.05E-13 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS27205 00849cd01e414135a30fd7c28bbd62ce 169 PANTHER PTHR33164 1 169 1.0E-100 T 23-04-2016 DC74_RS27205 00849cd01e414135a30fd7c28bbd62ce 169 Pfam PF01047 MarR family 62 113 3.0E-12 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS27205 00849cd01e414135a30fd7c28bbd62ce 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 2.1E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS27205 00849cd01e414135a30fd7c28bbd62ce 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 2.1E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS27205 00849cd01e414135a30fd7c28bbd62ce 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 2.1E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS27205 00849cd01e414135a30fd7c28bbd62ce 169 SMART SM00347 48 149 2.5E-22 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS27205 00849cd01e414135a30fd7c28bbd62ce 169 PANTHER PTHR33164:SF7 1 169 1.0E-100 T 23-04-2016 DC74_RS27205 00849cd01e414135a30fd7c28bbd62ce 169 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS27205 00849cd01e414135a30fd7c28bbd62ce 169 Gene3D G3DSA:1.10.10.10 27 160 4.2E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27205 00849cd01e414135a30fd7c28bbd62ce 169 SUPERFAMILY SSF46785 25 160 2.54E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09995 00f40c8af1e680ffc3f8bbc11c41d019 257 Pfam PF03704 Bacterial transcriptional activator domain 86 225 4.3E-21 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS09995 00f40c8af1e680ffc3f8bbc11c41d019 257 Pfam PF00486 Transcriptional regulatory protein, C terminal 5 71 1.5E-6 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS09995 00f40c8af1e680ffc3f8bbc11c41d019 257 SUPERFAMILY SSF46894 5 61 1.13E-7 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS09995 00f40c8af1e680ffc3f8bbc11c41d019 257 PANTHER PTHR35807 4 235 1.5E-26 T 23-04-2016 DC74_RS09995 00f40c8af1e680ffc3f8bbc11c41d019 257 SMART SM01043 85 230 5.2E-14 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain DC74_RS09995 00f40c8af1e680ffc3f8bbc11c41d019 257 SUPERFAMILY SSF48452 82 237 6.45E-18 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS09995 00f40c8af1e680ffc3f8bbc11c41d019 257 Gene3D G3DSA:1.10.10.10 6 78 1.8E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38570 f884a8a62979f3a94ac86a6708cebcb5 216 PANTHER PTHR11079:SF77 30 197 3.7E-25 T 23-04-2016 DC74_RS38570 f884a8a62979f3a94ac86a6708cebcb5 216 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 41 137 3.0E-10 T 23-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 DC74_RS38570 f884a8a62979f3a94ac86a6708cebcb5 216 Gene3D G3DSA:3.40.140.10 27 187 3.5E-30 T 23-04-2016 DC74_RS38570 f884a8a62979f3a94ac86a6708cebcb5 216 PANTHER PTHR11079 30 197 3.7E-25 T 23-04-2016 DC74_RS38570 f884a8a62979f3a94ac86a6708cebcb5 216 SUPERFAMILY SSF53927 26 191 3.72E-31 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS26720 65f3b23f1b36ea4da917c4ed180c0c04 149 PANTHER PTHR33164:SF2 1 149 4.5E-24 T 23-04-2016 DC74_RS26720 65f3b23f1b36ea4da917c4ed180c0c04 149 PANTHER PTHR33164 1 149 4.5E-24 T 23-04-2016 DC74_RS26720 65f3b23f1b36ea4da917c4ed180c0c04 149 SMART SM00347 29 129 2.7E-19 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS26720 65f3b23f1b36ea4da917c4ed180c0c04 149 Pfam PF01047 MarR family 38 94 1.0E-12 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS26720 65f3b23f1b36ea4da917c4ed180c0c04 149 SMART SM00418 37 114 0.0051 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS26720 65f3b23f1b36ea4da917c4ed180c0c04 149 SUPERFAMILY SSF46785 10 141 8.16E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26720 65f3b23f1b36ea4da917c4ed180c0c04 149 Gene3D G3DSA:1.10.10.10 10 141 1.6E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26720 65f3b23f1b36ea4da917c4ed180c0c04 149 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS18490 cfb69a691eed26361ee62d29af3431c8 477 Pfam PF01098 Cell cycle protein 75 445 5.9E-72 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 DC74_RS18490 cfb69a691eed26361ee62d29af3431c8 477 PANTHER PTHR30474:SF3 51 463 9.6E-174 T 23-04-2016 DC74_RS18490 cfb69a691eed26361ee62d29af3431c8 477 PANTHER PTHR30474 51 463 9.6E-174 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 DC74_RS06010 434b33f16b4cbe96ef3f62edecc96265 227 Pfam PF00551 Formyl transferase 70 159 1.1E-16 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS06010 434b33f16b4cbe96ef3f62edecc96265 227 PANTHER PTHR11138 11 51 1.8E-27 T 23-04-2016 DC74_RS06010 434b33f16b4cbe96ef3f62edecc96265 227 PANTHER PTHR11138 73 194 1.8E-27 T 23-04-2016 DC74_RS06010 434b33f16b4cbe96ef3f62edecc96265 227 SUPERFAMILY SSF53328 2 195 2.22E-34 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS06010 434b33f16b4cbe96ef3f62edecc96265 227 Gene3D G3DSA:3.40.50.170 2 196 5.8E-34 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 DC74_RS10165 d6353c9bb6fba1a24172910474f1a43e 491 PANTHER PTHR11785 28 491 3.0E-118 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS10165 d6353c9bb6fba1a24172910474f1a43e 491 TIGRFAM TIGR00908 2A0305: ethanolamine permease 30 477 4.6E-145 T 23-04-2016 IPR004757 Ethanolamine permease DC74_RS10165 d6353c9bb6fba1a24172910474f1a43e 491 PANTHER PTHR11785:SF337 28 491 3.0E-118 T 23-04-2016 DC74_RS10165 d6353c9bb6fba1a24172910474f1a43e 491 Pfam PF13520 Amino acid permease 62 447 3.0E-40 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS10165 d6353c9bb6fba1a24172910474f1a43e 491 PIRSF PIRSF006060 23 488 3.4E-63 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS29075 3490da259a17a7ccf0074d4736974823 93 Gene3D G3DSA:3.30.1340.10 1 88 5.4E-23 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like DC74_RS29075 3490da259a17a7ccf0074d4736974823 93 PANTHER PTHR33705 1 90 3.9E-34 T 23-04-2016 DC74_RS29075 3490da259a17a7ccf0074d4736974823 93 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 23-04-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site DC74_RS29075 3490da259a17a7ccf0074d4736974823 93 Pfam PF00381 PTS HPr component phosphorylation site 3 83 4.5E-20 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like DC74_RS29075 3490da259a17a7ccf0074d4736974823 93 PRINTS PR00107 Phosphocarrier protein signature 54 71 1.8E-9 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like DC74_RS29075 3490da259a17a7ccf0074d4736974823 93 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.8E-9 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like DC74_RS29075 3490da259a17a7ccf0074d4736974823 93 PRINTS PR00107 Phosphocarrier protein signature 39 54 1.8E-9 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like DC74_RS29075 3490da259a17a7ccf0074d4736974823 93 PANTHER PTHR33705:SF1 1 90 3.9E-34 T 23-04-2016 DC74_RS29075 3490da259a17a7ccf0074d4736974823 93 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 3.5E-24 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like DC74_RS29075 3490da259a17a7ccf0074d4736974823 93 SUPERFAMILY SSF55594 1 88 4.45E-18 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like DC74_RS14085 d543ce6ed4243c472e7e4eafc25803d4 306 PANTHER PTHR10584 1 299 6.7E-86 T 23-04-2016 DC74_RS14085 d543ce6ed4243c472e7e4eafc25803d4 306 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 244 257 - T 23-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 DC74_RS14085 d543ce6ed4243c472e7e4eafc25803d4 306 SUPERFAMILY SSF53613 1 299 2.03E-81 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS14085 d543ce6ed4243c472e7e4eafc25803d4 306 PANTHER PTHR10584:SF166 1 299 6.7E-86 T 23-04-2016 DC74_RS14085 d543ce6ed4243c472e7e4eafc25803d4 306 Gene3D G3DSA:3.40.1190.20 1 299 2.8E-94 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS14085 d543ce6ed4243c472e7e4eafc25803d4 306 PRINTS PR00990 Ribokinase signature 174 189 1.0E-30 T 23-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 DC74_RS14085 d543ce6ed4243c472e7e4eafc25803d4 306 PRINTS PR00990 Ribokinase signature 33 52 1.0E-30 T 23-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 DC74_RS14085 d543ce6ed4243c472e7e4eafc25803d4 306 PRINTS PR00990 Ribokinase signature 6 27 1.0E-30 T 23-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 DC74_RS14085 d543ce6ed4243c472e7e4eafc25803d4 306 PRINTS PR00990 Ribokinase signature 215 226 1.0E-30 T 23-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 DC74_RS14085 d543ce6ed4243c472e7e4eafc25803d4 306 PRINTS PR00990 Ribokinase signature 105 118 1.0E-30 T 23-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 DC74_RS14085 d543ce6ed4243c472e7e4eafc25803d4 306 Pfam PF00294 pfkB family carbohydrate kinase 3 292 3.6E-70 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS08795 d8f3dbb9ad54652a1e52689fa142ac58 209 SUPERFAMILY SSF46689 15 93 4.16E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS08795 d8f3dbb9ad54652a1e52689fa142ac58 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.0E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS08795 d8f3dbb9ad54652a1e52689fa142ac58 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.0E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS08795 d8f3dbb9ad54652a1e52689fa142ac58 209 Gene3D G3DSA:1.10.357.10 16 197 1.3E-36 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS08795 d8f3dbb9ad54652a1e52689fa142ac58 209 PANTHER PTHR30055 18 197 2.2E-28 T 23-04-2016 DC74_RS08795 d8f3dbb9ad54652a1e52689fa142ac58 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 1.7E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS08795 d8f3dbb9ad54652a1e52689fa142ac58 209 Pfam PF16925 Bacterial transcriptional repressor C-terminal 98 196 7.0E-7 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS08795 d8f3dbb9ad54652a1e52689fa142ac58 209 SUPERFAMILY SSF48498 89 205 7.07E-22 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS20195 c6565305709b5a85d71f97740c243bd6 338 PANTHER PTHR11562 1 305 2.4E-89 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DC74_RS20195 c6565305709b5a85d71f97740c243bd6 338 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 25 298 1.3E-74 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DC74_RS20195 c6565305709b5a85d71f97740c243bd6 338 SUPERFAMILY SSF160240 227 297 1.57E-8 T 23-04-2016 DC74_RS20195 c6565305709b5a85d71f97740c243bd6 338 SUPERFAMILY SSF161111 23 220 3.01E-50 T 23-04-2016 DC74_RS20195 c6565305709b5a85d71f97740c243bd6 338 Gene3D G3DSA:1.20.1510.10 25 219 6.8E-50 T 23-04-2016 IPR027469 Cation efflux protein transmembrane domain DC74_RS20195 c6565305709b5a85d71f97740c243bd6 338 Pfam PF01545 Cation efflux family 28 218 3.7E-42 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DC74_RS31470 bd8516b7474de1e1a402082369f98939 278 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 56 277 4.3E-42 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS31470 bd8516b7474de1e1a402082369f98939 278 PANTHER PTHR18966 51 277 1.4E-99 T 23-04-2016 DC74_RS31470 bd8516b7474de1e1a402082369f98939 278 SUPERFAMILY SSF53850 1 277 3.59E-54 T 23-04-2016 DC74_RS31470 bd8516b7474de1e1a402082369f98939 278 Gene3D G3DSA:3.40.190.10 167 226 5.8E-6 T 23-04-2016 DC74_RS31470 bd8516b7474de1e1a402082369f98939 278 PANTHER PTHR18966:SF243 51 277 1.4E-99 T 23-04-2016 DC74_RS31470 bd8516b7474de1e1a402082369f98939 278 Gene3D G3DSA:3.40.190.10 31 166 3.9E-32 T 23-04-2016 DC74_RS31470 bd8516b7474de1e1a402082369f98939 278 SMART SM00062 55 278 2.7E-39 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS19855 43a16bb1115cf6cf8bc87cea94de19eb 441 SUPERFAMILY SSF53383 26 425 5.39E-77 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS19855 43a16bb1115cf6cf8bc87cea94de19eb 441 Gene3D G3DSA:3.40.640.10 94 271 6.1E-19 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS19855 43a16bb1115cf6cf8bc87cea94de19eb 441 PANTHER PTHR14084 22 434 6.9E-124 T 23-04-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 DC74_RS19855 43a16bb1115cf6cf8bc87cea94de19eb 441 Gene3D G3DSA:3.90.1150.10 272 426 1.9E-44 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS19855 43a16bb1115cf6cf8bc87cea94de19eb 441 Pfam PF00266 Aminotransferase class-V 88 355 1.7E-16 T 23-04-2016 IPR000192 Aminotransferase class V domain DC74_RS19855 43a16bb1115cf6cf8bc87cea94de19eb 441 PIRSF PIRSF038800 17 430 2.7E-125 T 23-04-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 DC74_RS19855 43a16bb1115cf6cf8bc87cea94de19eb 441 Hamap MF_01970 Kynureninase [kynU]. 6 424 32.825 T 23-04-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 DC74_RS37305 ad174a2df25f2e65a6e0c30d8a468635 327 ProSitePatterns PS00770 Aminotransferases class-IV signature. 204 233 - T 23-04-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS37305 ad174a2df25f2e65a6e0c30d8a468635 327 Gene3D G3DSA:3.30.470.10 25 130 1.7E-19 T 23-04-2016 DC74_RS37305 ad174a2df25f2e65a6e0c30d8a468635 327 PANTHER PTHR11825:SF7 29 313 1.8E-58 T 23-04-2016 DC74_RS37305 ad174a2df25f2e65a6e0c30d8a468635 327 Pfam PF01063 Amino-transferase class IV 37 277 1.9E-39 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS37305 ad174a2df25f2e65a6e0c30d8a468635 327 SUPERFAMILY SSF56752 25 309 1.09E-69 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS37305 ad174a2df25f2e65a6e0c30d8a468635 327 PANTHER PTHR11825 29 313 1.8E-58 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 DC74_RS37305 ad174a2df25f2e65a6e0c30d8a468635 327 Gene3D G3DSA:3.20.10.10 140 304 1.9E-44 T 23-04-2016 DC74_RS33920 603c26eb1c44b6d063388371bb4e0a7d 436 PANTHER PTHR38133:SF1 16 436 4.4E-87 T 23-04-2016 DC74_RS33920 603c26eb1c44b6d063388371bb4e0a7d 436 PANTHER PTHR38133 16 436 4.4E-87 T 23-04-2016 DC74_RS07340 cecd77f2fdf5848198fdf88a45366e06 280 PANTHER PTHR11908:SF68 22 168 7.0E-25 T 23-04-2016 DC74_RS07340 cecd77f2fdf5848198fdf88a45366e06 280 PANTHER PTHR11908 22 168 7.0E-25 T 23-04-2016 DC74_RS07340 cecd77f2fdf5848198fdf88a45366e06 280 Gene3D G3DSA:3.30.465.10 57 169 2.7E-23 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS07340 cecd77f2fdf5848198fdf88a45366e06 280 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 25 169 7.2E-19 T 23-04-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DC74_RS07340 cecd77f2fdf5848198fdf88a45366e06 280 SUPERFAMILY SSF56176 21 169 5.12E-27 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 PANTHER PTHR18919 1 385 2.5E-200 T 23-04-2016 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 Pfam PF00108 Thiolase, N-terminal domain 5 254 1.2E-57 T 23-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 PANTHER PTHR18919:SF71 1 385 2.5E-200 T 23-04-2016 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 Gene3D G3DSA:3.40.47.10 196 268 1.8E-59 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 Gene3D G3DSA:3.40.47.10 4 124 1.8E-59 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 SUPERFAMILY SSF53901 3 262 1.15E-67 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 Pfam PF02803 Thiolase, C-terminal domain 263 384 1.0E-44 T 23-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 PIRSF PIRSF000429 1 385 8.5E-123 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 ProSitePatterns PS00737 Thiolases signature 2. 331 347 - T 23-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 SUPERFAMILY SSF53901 263 384 2.99E-42 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 383 2.5E-126 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 Gene3D G3DSA:3.40.47.10 159 195 2.6E-57 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS36350 de627683c8e6c8adb4b886d505f4ea08 385 Gene3D G3DSA:3.40.47.10 269 384 2.6E-57 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS32025 7ad99e0817d873260772a3dcb1423d27 600 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS32025 7ad99e0817d873260772a3dcb1423d27 600 Gene3D G3DSA:2.30.38.10 404 463 1.4E-18 T 23-04-2016 DC74_RS32025 7ad99e0817d873260772a3dcb1423d27 600 Gene3D G3DSA:3.30.300.30 467 588 8.8E-6 T 23-04-2016 DC74_RS32025 7ad99e0817d873260772a3dcb1423d27 600 SUPERFAMILY SSF56801 340 598 4.97E-110 T 23-04-2016 DC74_RS32025 7ad99e0817d873260772a3dcb1423d27 600 SUPERFAMILY SSF56801 10 286 4.97E-110 T 23-04-2016 DC74_RS32025 7ad99e0817d873260772a3dcb1423d27 600 Gene3D G3DSA:3.40.50.980 14 182 3.4E-32 T 23-04-2016 DC74_RS32025 7ad99e0817d873260772a3dcb1423d27 600 Pfam PF00501 AMP-binding enzyme 16 469 1.2E-91 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS32025 7ad99e0817d873260772a3dcb1423d27 600 PANTHER PTHR24096:SF193 10 599 3.5E-199 T 23-04-2016 DC74_RS32025 7ad99e0817d873260772a3dcb1423d27 600 PANTHER PTHR24096 10 599 3.5E-199 T 23-04-2016 DC74_RS32025 7ad99e0817d873260772a3dcb1423d27 600 Gene3D G3DSA:3.40.50.980 337 402 3.5E-28 T 23-04-2016 DC74_RS32025 7ad99e0817d873260772a3dcb1423d27 600 Gene3D G3DSA:3.40.50.980 183 281 3.5E-28 T 23-04-2016 DC74_RS15060 3f0eef3342fa2d9b56fc5780fe761a27 708 Gene3D G3DSA:3.30.450.40 269 433 7.1E-14 T 23-04-2016 IPR029016 GAF domain-like DC74_RS15060 3f0eef3342fa2d9b56fc5780fe761a27 708 SMART SM00065 277 435 0.0091 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS15060 3f0eef3342fa2d9b56fc5780fe761a27 708 PANTHER PTHR21021:SF19 561 708 3.1E-46 T 23-04-2016 DC74_RS15060 3f0eef3342fa2d9b56fc5780fe761a27 708 PANTHER PTHR21021:SF19 420 532 3.1E-46 T 23-04-2016 DC74_RS15060 3f0eef3342fa2d9b56fc5780fe761a27 708 SMART SM00331 456 703 1.7E-32 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS15060 3f0eef3342fa2d9b56fc5780fe761a27 708 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 482 702 5.8E-40 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS15060 3f0eef3342fa2d9b56fc5780fe761a27 708 PANTHER PTHR21021 561 708 3.1E-46 T 23-04-2016 DC74_RS15060 3f0eef3342fa2d9b56fc5780fe761a27 708 PANTHER PTHR21021 420 532 3.1E-46 T 23-04-2016 DC74_RS15060 3f0eef3342fa2d9b56fc5780fe761a27 708 Pfam PF13185 GAF domain 280 425 3.8E-8 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS15060 3f0eef3342fa2d9b56fc5780fe761a27 708 SUPERFAMILY SSF55781 281 436 1.48E-13 T 23-04-2016 IPR029016 GAF domain-like DC74_RS05365 13698d0ba10ebf952da255693405b51d 277 PANTHER PTHR11941 1 269 4.1E-60 T 23-04-2016 DC74_RS05365 13698d0ba10ebf952da255693405b51d 277 Gene3D G3DSA:3.90.226.10 14 270 8.8E-60 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS05365 13698d0ba10ebf952da255693405b51d 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 270 7.8E-42 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS05365 13698d0ba10ebf952da255693405b51d 277 PANTHER PTHR11941:SF13 1 269 4.1E-60 T 23-04-2016 DC74_RS05365 13698d0ba10ebf952da255693405b51d 277 SUPERFAMILY SSF52096 13 270 6.75E-62 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS19730 3a65afd95dfd453c662fb8d04aa49cb4 87 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 22.055 T 23-04-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19730 3a65afd95dfd453c662fb8d04aa49cb4 87 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 6.0E-32 T 23-04-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19730 3a65afd95dfd453c662fb8d04aa49cb4 87 Gene3D G3DSA:3.30.1280.10 3 81 1.7E-33 T 23-04-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19730 3a65afd95dfd453c662fb8d04aa49cb4 87 PANTHER PTHR34696 1 85 2.4E-34 T 23-04-2016 DC74_RS19730 3a65afd95dfd453c662fb8d04aa49cb4 87 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 79 6.2E-29 T 23-04-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS19730 3a65afd95dfd453c662fb8d04aa49cb4 87 SUPERFAMILY SSF82697 3 81 1.73E-25 T 23-04-2016 DC74_RS19730 3a65afd95dfd453c662fb8d04aa49cb4 87 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 81 1.1E-21 T 23-04-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 DC74_RS32875 f03b3432e58ec1f204764beefdc8ecbf 429 Pfam PF13810 Domain of unknown function (DUF4185) 240 384 3.7E-9 T 23-04-2016 IPR025442 Domain of unknown function DUF4185 DC74_RS15100 bbd6edddb8b11fd00c18229e6a819d4b 768 PANTHER PTHR30619 176 753 9.4E-130 T 23-04-2016 DC74_RS15100 bbd6edddb8b11fd00c18229e6a819d4b 768 SUPERFAMILY SSF56281 496 752 2.66E-37 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS15100 bbd6edddb8b11fd00c18229e6a819d4b 768 SMART SM00849 510 713 1.6E-4 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS15100 bbd6edddb8b11fd00c18229e6a819d4b 768 Gene3D G3DSA:3.60.15.10 499 736 7.1E-22 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS15100 bbd6edddb8b11fd00c18229e6a819d4b 768 PANTHER PTHR30619:SF2 176 753 9.4E-130 T 23-04-2016 DC74_RS15100 bbd6edddb8b11fd00c18229e6a819d4b 768 Pfam PF03772 Competence protein 187 461 5.3E-39 T 23-04-2016 IPR004477 ComEC/Rec2-related protein DC74_RS15100 bbd6edddb8b11fd00c18229e6a819d4b 768 Pfam PF00753 Metallo-beta-lactamase superfamily 516 680 7.4E-6 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS15100 bbd6edddb8b11fd00c18229e6a819d4b 768 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 209 385 1.6E-11 T 23-04-2016 IPR004477 ComEC/Rec2-related protein DC74_RS32430 4484f7a54620a576d16f3db5e8972af4 414 Gene3D G3DSA:3.40.50.150 92 249 8.1E-8 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS32430 4484f7a54620a576d16f3db5e8972af4 414 Pfam PF08484 C-methyltransferase C-terminal domain 246 404 4.1E-46 T 23-04-2016 IPR013691 C-methyltransferase KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.-|UniPathway: UPA00853 DC74_RS32430 4484f7a54620a576d16f3db5e8972af4 414 Pfam PF08421 Putative zinc binding domain 6 67 3.3E-16 T 23-04-2016 IPR013630 Methyltransferase putative zinc binding domain KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.-|UniPathway: UPA00853 DC74_RS32430 4484f7a54620a576d16f3db5e8972af4 414 Pfam PF13489 Methyltransferase domain 98 239 1.1E-9 T 23-04-2016 DC74_RS32430 4484f7a54620a576d16f3db5e8972af4 414 SUPERFAMILY SSF53335 67 242 8.66E-14 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS36370 bceb1ecdda1eabfc78a20ed865550c1a 279 PANTHER PTHR13707 3 248 3.9E-61 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 DC74_RS36370 bceb1ecdda1eabfc78a20ed865550c1a 279 SMART SM00882 5 224 3.4E-29 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 DC74_RS36370 bceb1ecdda1eabfc78a20ed865550c1a 279 PANTHER PTHR13707:SF34 3 248 3.9E-61 T 23-04-2016 DC74_RS36370 bceb1ecdda1eabfc78a20ed865550c1a 279 SUPERFAMILY SSF100950 3 256 3.95E-66 T 23-04-2016 DC74_RS36370 bceb1ecdda1eabfc78a20ed865550c1a 279 Pfam PF01144 Coenzyme A transferase 5 223 4.7E-36 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 DC74_RS36370 bceb1ecdda1eabfc78a20ed865550c1a 279 Gene3D G3DSA:3.40.1080.10 156 273 5.7E-69 T 23-04-2016 DC74_RS36370 bceb1ecdda1eabfc78a20ed865550c1a 279 Gene3D G3DSA:3.40.1080.10 3 117 5.7E-69 T 23-04-2016 DC74_RS23745 e2addfd6ecfc8454eac4fbbfc00e9c11 218 Gene3D G3DSA:3.40.50.300 25 201 1.3E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23745 e2addfd6ecfc8454eac4fbbfc00e9c11 218 PANTHER PTHR11711 30 205 1.3E-60 T 23-04-2016 DC74_RS23745 e2addfd6ecfc8454eac4fbbfc00e9c11 218 SUPERFAMILY SSF52540 27 203 6.99E-22 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23745 e2addfd6ecfc8454eac4fbbfc00e9c11 218 Pfam PF03029 Conserved hypothetical ATP binding protein 34 200 1.3E-24 T 23-04-2016 IPR004130 GPN-loop GTPase DC74_RS23745 e2addfd6ecfc8454eac4fbbfc00e9c11 218 PANTHER PTHR11711:SF117 30 205 1.3E-60 T 23-04-2016 DC74_RS24980 88e4e7e8e19a8bf4a33ec50f01a9d7ea 161 PANTHER PTHR36834 50 137 8.9E-13 T 23-04-2016 DC74_RS24980 88e4e7e8e19a8bf4a33ec50f01a9d7ea 161 Pfam PF04892 VanZ like family 3 120 3.3E-15 T 23-04-2016 IPR006976 VanZ-like DC74_RS24980 88e4e7e8e19a8bf4a33ec50f01a9d7ea 161 PANTHER PTHR36834:SF1 50 137 8.9E-13 T 23-04-2016 DC74_RS25425 a8faeaceb92afeecae66454a1bcbe5c7 297 PANTHER PTHR35007 1 292 2.2E-69 T 23-04-2016 DC74_RS25425 a8faeaceb92afeecae66454a1bcbe5c7 297 PANTHER PTHR35007:SF2 1 292 2.2E-69 T 23-04-2016 DC74_RS25425 a8faeaceb92afeecae66454a1bcbe5c7 297 Pfam PF00482 Type II secretion system (T2SS), protein F 154 280 1.5E-22 T 23-04-2016 IPR018076 Type II secretion system F domain DC74_RS19435 1f3b53b9a6e0cde17059150642c65ff1 552 Gene3D G3DSA:3.30.950.10 135 275 2.3E-30 T 23-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 DC74_RS19435 1f3b53b9a6e0cde17059150642c65ff1 552 SUPERFAMILY SSF69618 271 521 6.41E-66 T 23-04-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19435 1f3b53b9a6e0cde17059150642c65ff1 552 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 17 31 - T 23-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 DC74_RS19435 1f3b53b9a6e0cde17059150642c65ff1 552 SUPERFAMILY SSF53790 9 274 4.71E-44 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS19435 1f3b53b9a6e0cde17059150642c65ff1 552 Gene3D G3DSA:3.40.1010.10 11 133 1.1E-29 T 23-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 DC74_RS19435 1f3b53b9a6e0cde17059150642c65ff1 552 PANTHER PTHR21091 12 223 1.3E-55 T 23-04-2016 DC74_RS19435 1f3b53b9a6e0cde17059150642c65ff1 552 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 226 1.4E-34 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS19435 1f3b53b9a6e0cde17059150642c65ff1 552 Pfam PF02602 Uroporphyrinogen-III synthase HemD 285 515 9.3E-64 T 23-04-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 DC74_RS19435 1f3b53b9a6e0cde17059150642c65ff1 552 PANTHER PTHR21091:SF128 12 223 1.3E-55 T 23-04-2016 DC74_RS19435 1f3b53b9a6e0cde17059150642c65ff1 552 Gene3D G3DSA:3.40.50.10090 276 398 2.4E-40 T 23-04-2016 DC74_RS19435 1f3b53b9a6e0cde17059150642c65ff1 552 Gene3D G3DSA:3.40.50.10090 406 524 1.4E-34 T 23-04-2016 DC74_RS21570 d503d516c7005599620733cb0886b2e1 158 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 116 1.1E-48 T 23-04-2016 IPR028973 3-demethylubiquinone-9 3-methyltransferase DC74_RS21570 d503d516c7005599620733cb0886b2e1 158 Gene3D G3DSA:3.10.180.10 1 128 6.0E-48 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS21570 d503d516c7005599620733cb0886b2e1 158 PANTHER PTHR33990 1 157 3.5E-77 T 23-04-2016 DC74_RS21570 d503d516c7005599620733cb0886b2e1 158 PANTHER PTHR33990:SF2 1 157 3.5E-77 T 23-04-2016 DC74_RS21570 d503d516c7005599620733cb0886b2e1 158 PIRSF PIRSF021700 1 156 2.1E-64 T 23-04-2016 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase DC74_RS21570 d503d516c7005599620733cb0886b2e1 158 SUPERFAMILY SSF54593 3 154 9.85E-49 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 PANTHER PTHR11347 371 463 6.4E-40 T 23-04-2016 DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 Pfam PF13185 GAF domain 174 332 3.8E-14 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 Pfam PF13185 GAF domain 8 145 7.4E-20 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 PANTHER PTHR11347:SF114 371 463 6.4E-40 T 23-04-2016 IPR027035 Hypoxia/Redox sensor histidine kinase response regulator DosT/DevS GO:0004673|GO:0046777|GO:0070483 DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 Pfam PF07730 Histidine kinase 349 411 4.5E-11 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 PANTHER PTHR11347 7 257 6.4E-40 T 23-04-2016 DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 SUPERFAMILY SSF55874 443 504 1.04E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 Gene3D G3DSA:3.30.450.40 153 343 7.5E-24 T 23-04-2016 IPR029016 GAF domain-like DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 Gene3D G3DSA:3.30.565.10 452 502 3.5E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 PANTHER PTHR11347:SF114 275 342 6.4E-40 T 23-04-2016 IPR027035 Hypoxia/Redox sensor histidine kinase response regulator DosT/DevS GO:0004673|GO:0046777|GO:0070483 DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 SUPERFAMILY SSF55781 4 173 4.8E-37 T 23-04-2016 IPR029016 GAF domain-like DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 SUPERFAMILY SSF55781 157 353 4.74E-24 T 23-04-2016 IPR029016 GAF domain-like DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 Gene3D G3DSA:3.30.450.40 3 152 1.5E-29 T 23-04-2016 IPR029016 GAF domain-like DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 PANTHER PTHR11347:SF114 7 257 6.4E-40 T 23-04-2016 IPR027035 Hypoxia/Redox sensor histidine kinase response regulator DosT/DevS GO:0004673|GO:0046777|GO:0070483 DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 SMART SM00065 175 341 2.0E-8 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 SMART SM00065 8 154 7.5E-17 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS03875 d1425b0de15174a7e0dee9f780e3bb66 543 PANTHER PTHR11347 275 342 6.4E-40 T 23-04-2016 DC74_RS10570 940b4059bd684007a1dd94845ad10abd 217 PANTHER PTHR30055 1 114 2.0E-13 T 23-04-2016 DC74_RS10570 940b4059bd684007a1dd94845ad10abd 217 PANTHER PTHR30055:SF73 1 114 2.0E-13 T 23-04-2016 DC74_RS10570 940b4059bd684007a1dd94845ad10abd 217 Gene3D G3DSA:1.10.357.10 2 206 2.0E-22 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS10570 940b4059bd684007a1dd94845ad10abd 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 60 2.7E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10570 940b4059bd684007a1dd94845ad10abd 217 SUPERFAMILY SSF46689 3 80 1.18E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS25530 c926c0a15ab0309950be1904400e9c14 174 PANTHER PTHR33169 1 170 2.0E-59 T 23-04-2016 DC74_RS25530 c926c0a15ab0309950be1904400e9c14 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 6.8E-16 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS25530 c926c0a15ab0309950be1904400e9c14 174 PANTHER PTHR33169:SF2 1 170 2.0E-59 T 23-04-2016 DC74_RS25530 c926c0a15ab0309950be1904400e9c14 174 Gene3D G3DSA:1.10.10.10 1 87 1.3E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25530 c926c0a15ab0309950be1904400e9c14 174 SUPERFAMILY SSF46785 3 168 4.43E-35 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03895 de6116596537ab250fcf8a7767e4abcc 255 Gene3D G3DSA:3.40.50.1820 23 247 5.0E-25 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS03895 de6116596537ab250fcf8a7767e4abcc 255 SUPERFAMILY SSF53474 15 90 2.75E-22 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS03895 de6116596537ab250fcf8a7767e4abcc 255 SUPERFAMILY SSF53474 123 248 2.75E-22 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS31815 40d13788ede24e994805e612d86f224d 147 Gene3D G3DSA:3.30.530.20 4 146 2.1E-9 T 23-04-2016 IPR023393 START-like domain DC74_RS31815 40d13788ede24e994805e612d86f224d 147 PIRSF PIRSF017371 1 147 2.8E-71 T 23-04-2016 IPR014488 Uncharacterised conserved protein UCP017371 DC74_RS31815 40d13788ede24e994805e612d86f224d 147 SUPERFAMILY SSF55961 3 144 2.31E-20 T 23-04-2016 DC74_RS31815 40d13788ede24e994805e612d86f224d 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 146 3.4E-25 T 23-04-2016 IPR019587 Polyketide cyclase/dehydrase DC74_RS35135 75acb3b5688feeb00bd709de4be03c91 188 PANTHER PTHR13061 3 173 2.0E-71 T 23-04-2016 DC74_RS35135 75acb3b5688feeb00bd709de4be03c91 188 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 92 125 9.9E-6 T 23-04-2016 IPR001451 Hexapeptide repeat DC74_RS35135 75acb3b5688feeb00bd709de4be03c91 188 SUPERFAMILY SSF51161 10 172 9.56E-47 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS35135 75acb3b5688feeb00bd709de4be03c91 188 Gene3D G3DSA:2.160.10.10 8 171 5.8E-47 T 23-04-2016 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 SUPERFAMILY SSF48264 16 401 2.75E-92 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PANTHER PTHR24286:SF42 41 402 4.3E-81 T 23-04-2016 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00385 P450 superfamily signature 345 354 2.9E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00385 P450 superfamily signature 354 365 2.9E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00385 P450 superfamily signature 278 289 2.9E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00385 P450 superfamily signature 243 260 2.9E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 Pfam PF00067 Cytochrome P450 43 387 6.0E-34 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 Gene3D G3DSA:1.10.630.10 15 402 1.9E-117 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PANTHER PTHR24286 41 402 4.3E-81 T 23-04-2016 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00359 B-class P450 signature 151 166 6.3E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00359 B-class P450 signature 278 289 6.3E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00359 B-class P450 signature 134 150 6.3E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00359 B-class P450 signature 345 354 6.3E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00359 B-class P450 signature 354 365 6.3E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00359 B-class P450 signature 84 95 6.3E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00359 B-class P450 signature 197 219 6.3E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00359 B-class P450 signature 296 323 6.3E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 PRINTS PR00359 B-class P450 signature 324 339 6.3E-53 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS37505 a729a468094e597aea8b886ae652fc14 406 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 347 356 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS38015 78551c50bc640e268622c0ec1956009a 278 Gene3D G3DSA:3.40.50.150 56 233 7.5E-39 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS38015 78551c50bc640e268622c0ec1956009a 278 PANTHER PTHR10108 53 182 2.8E-31 T 23-04-2016 DC74_RS38015 78551c50bc640e268622c0ec1956009a 278 SUPERFAMILY SSF53335 54 270 8.59E-42 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS38015 78551c50bc640e268622c0ec1956009a 278 Pfam PF08241 Methyltransferase domain 89 180 1.9E-25 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS06095 7702f1285f3d634dc116364a85d9394e 198 Gene3D G3DSA:1.10.357.10 3 187 5.7E-37 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS06095 7702f1285f3d634dc116364a85d9394e 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.3E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS06095 7702f1285f3d634dc116364a85d9394e 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.3E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS06095 7702f1285f3d634dc116364a85d9394e 198 PANTHER PTHR30055:SF47 2 189 5.7E-32 T 23-04-2016 DC74_RS06095 7702f1285f3d634dc116364a85d9394e 198 SUPERFAMILY SSF46689 6 71 1.85E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06095 7702f1285f3d634dc116364a85d9394e 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 58 8.5E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS06095 7702f1285f3d634dc116364a85d9394e 198 PANTHER PTHR30055 2 189 5.7E-32 T 23-04-2016 DC74_RS06095 7702f1285f3d634dc116364a85d9394e 198 SUPERFAMILY SSF48498 79 187 3.34E-25 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS01075 1902ae02ebed098bd66ca03ccef2d720 256 SUPERFAMILY SSF46785 1 72 1.98E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01075 1902ae02ebed098bd66ca03ccef2d720 256 Pfam PF01614 Bacterial transcriptional regulator 120 242 2.0E-30 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS01075 1902ae02ebed098bd66ca03ccef2d720 256 PANTHER PTHR30136 1 256 2.3E-62 T 23-04-2016 DC74_RS01075 1902ae02ebed098bd66ca03ccef2d720 256 SUPERFAMILY SSF55781 75 246 3.14E-50 T 23-04-2016 IPR029016 GAF domain-like DC74_RS01075 1902ae02ebed098bd66ca03ccef2d720 256 Gene3D G3DSA:1.10.10.10 1 72 7.8E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01075 1902ae02ebed098bd66ca03ccef2d720 256 Gene3D G3DSA:3.30.450.40 76 247 1.4E-54 T 23-04-2016 IPR029016 GAF domain-like DC74_RS01075 1902ae02ebed098bd66ca03ccef2d720 256 SMART SM00346 1 91 1.5E-16 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS01075 1902ae02ebed098bd66ca03ccef2d720 256 Pfam PF09339 IclR helix-turn-helix domain 4 50 1.8E-9 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS14465 c08be070b4a869f2bf08aff3e30b62df 349 Gene3D G3DSA:3.90.1690.10 90 292 1.0E-8 T 23-04-2016 DC74_RS14465 c08be070b4a869f2bf08aff3e30b62df 349 Pfam PF03864 Phage major capsid protein E 13 346 1.9E-31 T 23-04-2016 IPR005564 Major capsid protein GpE GO:0019028 DC74_RS29920 d6c6dedb862deea4f12eab9196d5cbcb 236 Gene3D G3DSA:2.70.70.10 104 221 1.4E-33 T 23-04-2016 DC74_RS29920 d6c6dedb862deea4f12eab9196d5cbcb 236 PANTHER PTHR21666 113 219 4.9E-26 T 23-04-2016 DC74_RS29920 d6c6dedb862deea4f12eab9196d5cbcb 236 Gene3D G3DSA:1.10.101.10 22 89 1.0E-7 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS29920 d6c6dedb862deea4f12eab9196d5cbcb 236 SUPERFAMILY SSF51261 101 224 1.1E-34 T 23-04-2016 IPR011055 Duplicated hybrid motif DC74_RS29920 d6c6dedb862deea4f12eab9196d5cbcb 236 SUPERFAMILY SSF47090 21 88 8.63E-7 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS29920 d6c6dedb862deea4f12eab9196d5cbcb 236 Pfam PF01551 Peptidase family M23 134 221 2.4E-25 T 23-04-2016 IPR016047 Peptidase M23 DC74_RS39730 ea281ce4155450e24ed715144bfeab61 184 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 3 171 1.5E-65 T 23-04-2016 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 DC74_RS39730 ea281ce4155450e24ed715144bfeab61 184 SUPERFAMILY SSF52218 3 170 1.23E-30 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS39730 ea281ce4155450e24ed715144bfeab61 184 PANTHER PTHR30543 1 176 2.6E-32 T 23-04-2016 DC74_RS39730 ea281ce4155450e24ed715144bfeab61 184 PANTHER PTHR30543:SF1 1 176 2.6E-32 T 23-04-2016 DC74_RS39730 ea281ce4155450e24ed715144bfeab61 184 Gene3D G3DSA:3.40.50.360 1 177 5.7E-32 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS39730 ea281ce4155450e24ed715144bfeab61 184 Pfam PF03358 NADPH-dependent FMN reductase 4 143 6.6E-30 T 23-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 DC74_RS20400 79cf71eff76f29f64b550ddedb11916f 379 SUPERFAMILY SSF81324 31 167 1.11E-20 T 23-04-2016 DC74_RS20400 79cf71eff76f29f64b550ddedb11916f 379 Gene3D G3DSA:3.40.50.720 136 274 3.8E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20400 79cf71eff76f29f64b550ddedb11916f 379 PANTHER PTHR16254:SF21 31 305 6.3E-71 T 23-04-2016 DC74_RS20400 79cf71eff76f29f64b550ddedb11916f 379 SUPERFAMILY SSF51735 140 282 6.73E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20400 79cf71eff76f29f64b550ddedb11916f 379 Pfam PF02254 TrkA-N domain 145 261 7.4E-28 T 23-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 DC74_RS20400 79cf71eff76f29f64b550ddedb11916f 379 Gene3D G3DSA:1.10.287.70 41 134 1.6E-13 T 23-04-2016 DC74_RS20400 79cf71eff76f29f64b550ddedb11916f 379 PANTHER PTHR16254 31 305 6.3E-71 T 23-04-2016 DC74_RS20400 79cf71eff76f29f64b550ddedb11916f 379 Pfam PF07885 Ion channel 41 124 5.4E-12 T 23-04-2016 IPR013099 Potassium channel domain DC74_RS05940 87434eb1a5f73b372fb680d6667946ee 267 SUPERFAMILY SSF143631 9 252 1.02E-60 T 23-04-2016 IPR003374 ApbE-like domain DC74_RS05940 87434eb1a5f73b372fb680d6667946ee 267 Pfam PF02424 ApbE family 100 228 1.0E-32 T 23-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 DC74_RS05940 87434eb1a5f73b372fb680d6667946ee 267 Pfam PF02424 ApbE family 15 99 9.2E-10 T 23-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 DC74_RS05940 87434eb1a5f73b372fb680d6667946ee 267 PANTHER PTHR30040 6 260 5.5E-49 T 23-04-2016 DC74_RS01790 312634e6a2bda816f21367957a8f0509 144 SUPERFAMILY SSF102462 10 144 4.34E-46 T 23-04-2016 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 DC74_RS01790 312634e6a2bda816f21367957a8f0509 144 Pfam PF09391 Protein of unknown function (DUF2000) 13 143 2.2E-44 T 23-04-2016 IPR018988 Protein of unknown function DUF2000 DC74_RS01790 312634e6a2bda816f21367957a8f0509 144 Gene3D G3DSA:3.40.1490.10 10 144 1.7E-64 T 23-04-2016 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 DC74_RS23495 ecae83c44f47e3bc01f5565e37bb07ae 422 Gene3D G3DSA:3.40.190.10 166 350 2.3E-34 T 23-04-2016 DC74_RS23495 ecae83c44f47e3bc01f5565e37bb07ae 422 SUPERFAMILY SSF53850 50 414 4.55E-58 T 23-04-2016 DC74_RS23495 ecae83c44f47e3bc01f5565e37bb07ae 422 Pfam PF13416 Bacterial extracellular solute-binding protein 57 362 4.3E-35 T 23-04-2016 DC74_RS23495 ecae83c44f47e3bc01f5565e37bb07ae 422 PANTHER PTHR30061:SF1 2 352 2.4E-51 T 23-04-2016 DC74_RS23495 ecae83c44f47e3bc01f5565e37bb07ae 422 Gene3D G3DSA:3.40.190.10 52 165 8.7E-18 T 23-04-2016 DC74_RS23495 ecae83c44f47e3bc01f5565e37bb07ae 422 PANTHER PTHR30061 2 352 2.4E-51 T 23-04-2016 DC74_RS13975 2c41e1a677d39145d76b671aadd9c6bd 404 SUPERFAMILY SSF53474 251 338 3.0E-6 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS13975 2c41e1a677d39145d76b671aadd9c6bd 404 Pfam PF06259 Alpha/beta hydrolase 164 337 3.2E-60 T 23-04-2016 IPR010427 Protein of unknown function DUF1023 DC74_RS13975 2c41e1a677d39145d76b671aadd9c6bd 404 Gene3D G3DSA:3.40.50.1820 225 340 5.6E-5 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 Gene3D G3DSA:3.30.450.40 255 442 5.5E-12 T 23-04-2016 IPR029016 GAF domain-like DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 SUPERFAMILY SSF55781 352 443 2.19E-8 T 23-04-2016 IPR029016 GAF domain-like DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 SUPERFAMILY SSF55785 107 199 3.01E-12 T 23-04-2016 IPR000014 PAS domain DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 Gene3D G3DSA:3.30.450.20 108 236 8.6E-16 T 23-04-2016 DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 2 100 1.6E-9 T 23-04-2016 IPR000014 PAS domain DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 SUPERFAMILY SSF55785 2 100 2.79E-14 T 23-04-2016 IPR000014 PAS domain DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 Gene3D G3DSA:3.30.450.20 2 100 2.0E-14 T 23-04-2016 DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 PANTHER PTHR24423 1 242 7.1E-17 T 23-04-2016 DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 SMART SM00091 1 60 17.0 T 23-04-2016 IPR000014 PAS domain DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 SMART SM00091 116 181 0.0056 T 23-04-2016 IPR000014 PAS domain DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 Pfam PF08448 PAS fold 3 101 1.6E-7 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 Pfam PF08448 PAS fold 123 239 1.8E-7 T 23-04-2016 IPR013656 PAS fold-4 DC74_RS23905 0220ef78ad2443cf668cdee858f595a4 448 Pfam PF01590 GAF domain 362 440 8.4E-5 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS34870 77168685cb6a2a6e1340e5b21fbe4862 94 SUPERFAMILY SSF54427 1 90 1.25E-27 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS34870 77168685cb6a2a6e1340e5b21fbe4862 94 Gene3D G3DSA:3.10.450.50 1 90 9.5E-25 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS12430 3a14a944fe912c4bafa2af0cb94f8e71 422 Pfam PF01936 NYN domain 32 166 2.1E-11 T 23-04-2016 IPR021139 NYN domain, limkain-b1-type DC74_RS12430 3a14a944fe912c4bafa2af0cb94f8e71 422 Gene3D G3DSA:3.40.50.1010 3 171 2.4E-16 T 23-04-2016 IPR029060 PIN domain-like DC74_RS10940 42804f7a9b79570d08e761497a2a57b3 149 PANTHER PTHR35798 14 148 6.0E-31 T 23-04-2016 DC74_RS10940 42804f7a9b79570d08e761497a2a57b3 149 Pfam PF04472 Protein of unknown function (DUF552) 61 132 2.2E-24 T 23-04-2016 IPR007561 Cell division protein SepF/SepF-related GO:0000917 DC74_RS10940 42804f7a9b79570d08e761497a2a57b3 149 PANTHER PTHR35798:SF1 14 148 6.0E-31 T 23-04-2016 DC74_RS10940 42804f7a9b79570d08e761497a2a57b3 149 Hamap MF_01197 Cell division protein SepF [sepF]. 1 141 19.324 T 23-04-2016 IPR023052 Cell division protein SepF GO:0090529 DC74_RS29250 d1c946c749ecb272295eadc0f0a98928 446 Pfam PF01938 TRAM domain 11 71 5.8E-15 T 23-04-2016 IPR002792 TRAM domain DC74_RS29250 d1c946c749ecb272295eadc0f0a98928 446 PANTHER PTHR11061:SF30 4 446 2.9E-104 T 23-04-2016 DC74_RS29250 d1c946c749ecb272295eadc0f0a98928 446 SUPERFAMILY SSF50249 11 60 1.83E-10 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS29250 d1c946c749ecb272295eadc0f0a98928 446 SUPERFAMILY SSF53335 79 441 2.62E-54 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS29250 d1c946c749ecb272295eadc0f0a98928 446 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 424 434 - T 23-04-2016 IPR030391 RNA methyltransferase TrmA, conserved site DC74_RS29250 d1c946c749ecb272295eadc0f0a98928 446 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 367 441 6.4E-11 T 23-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 DC74_RS29250 d1c946c749ecb272295eadc0f0a98928 446 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 266 343 1.6E-5 T 23-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 DC74_RS29250 d1c946c749ecb272295eadc0f0a98928 446 PANTHER PTHR11061 4 446 2.9E-104 T 23-04-2016 DC74_RS29250 d1c946c749ecb272295eadc0f0a98928 446 Gene3D G3DSA:2.40.50.140 14 89 2.9E-23 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS29250 d1c946c749ecb272295eadc0f0a98928 446 Gene3D G3DSA:3.40.50.150 248 440 1.0E-49 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS18835 33a80229db669f0f874d488ea98f8e95 144 Pfam PF01575 MaoC like domain 15 118 4.2E-27 T 23-04-2016 IPR002539 MaoC-like domain DC74_RS18835 33a80229db669f0f874d488ea98f8e95 144 PANTHER PTHR13078 5 143 7.2E-22 T 23-04-2016 DC74_RS18835 33a80229db669f0f874d488ea98f8e95 144 Gene3D G3DSA:3.10.129.10 8 143 1.1E-40 T 23-04-2016 IPR029069 HotDog domain DC74_RS18835 33a80229db669f0f874d488ea98f8e95 144 SUPERFAMILY SSF54637 4 140 2.03E-30 T 23-04-2016 IPR029069 HotDog domain DC74_RS18835 33a80229db669f0f874d488ea98f8e95 144 PRINTS PR01483 Fatty acid synthase signature 25 47 4.6E-8 T 23-04-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 DC74_RS18835 33a80229db669f0f874d488ea98f8e95 144 PRINTS PR01483 Fatty acid synthase signature 47 68 4.6E-8 T 23-04-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 DC74_RS37425 87dd287c6e7766ebd5b8068bbcd8deff 429 SUPERFAMILY SSF88713 176 403 1.08E-23 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS37425 87dd287c6e7766ebd5b8068bbcd8deff 429 SUPERFAMILY SSF88713 103 146 1.08E-23 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS37425 87dd287c6e7766ebd5b8068bbcd8deff 429 Gene3D G3DSA:3.20.20.370 317 401 8.2E-12 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS37425 87dd287c6e7766ebd5b8068bbcd8deff 429 Gene3D G3DSA:3.20.20.370 96 275 8.2E-12 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS10175 3e40adff98da72c5df728581fbd81022 187 SMART SM00530 16 71 3.5E-12 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS10175 3e40adff98da72c5df728581fbd81022 187 Pfam PF01381 Helix-turn-helix 18 68 3.8E-10 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS10175 3e40adff98da72c5df728581fbd81022 187 SUPERFAMILY SSF51182 56 183 2.52E-19 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS10175 3e40adff98da72c5df728581fbd81022 187 PANTHER PTHR10245:SF9 12 169 5.6E-30 T 23-04-2016 DC74_RS10175 3e40adff98da72c5df728581fbd81022 187 SUPERFAMILY SSF47413 12 75 1.64E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS10175 3e40adff98da72c5df728581fbd81022 187 Gene3D G3DSA:1.10.260.40 13 88 6.1E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS10175 3e40adff98da72c5df728581fbd81022 187 PANTHER PTHR10245 12 169 5.6E-30 T 23-04-2016 DC74_RS10175 3e40adff98da72c5df728581fbd81022 187 Gene3D G3DSA:2.60.120.10 89 181 1.6E-17 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS10175 3e40adff98da72c5df728581fbd81022 187 Pfam PF07883 Cupin domain 125 170 8.4E-11 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS28910 cce373dba076a9e98f49ec8eaffb652b 226 SUPERFAMILY SSF55729 47 220 4.95E-47 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS28910 cce373dba076a9e98f49ec8eaffb652b 226 Pfam PF13523 Acetyltransferase (GNAT) domain 62 207 1.7E-48 T 23-04-2016 DC74_RS28910 cce373dba076a9e98f49ec8eaffb652b 226 Gene3D G3DSA:3.40.630.30 54 221 4.2E-51 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS28910 cce373dba076a9e98f49ec8eaffb652b 226 PANTHER PTHR31438:SF3 30 226 4.2E-78 T 23-04-2016 DC74_RS28910 cce373dba076a9e98f49ec8eaffb652b 226 PANTHER PTHR31438 30 226 4.2E-78 T 23-04-2016 DC74_RS28910 cce373dba076a9e98f49ec8eaffb652b 226 SMART SM01006 59 107 8.9E-15 T 23-04-2016 IPR019432 Siderophore biosynthesis protein, conserved domain DC74_RS35625 7e27d576376ed37f92c23fe820478a6c 231 SUPERFAMILY SSF52540 25 226 6.31E-35 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35625 7e27d576376ed37f92c23fe820478a6c 231 Hamap MF_01389 Urease accessory protein UreG [ureG]. 28 226 43.835 T 23-04-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 DC74_RS35625 7e27d576376ed37f92c23fe820478a6c 231 Gene3D G3DSA:3.40.50.300 28 214 7.2E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35625 7e27d576376ed37f92c23fe820478a6c 231 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 30 222 5.2E-83 T 23-04-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 DC74_RS35625 7e27d576376ed37f92c23fe820478a6c 231 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 32 201 2.5E-34 T 23-04-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain DC74_RS35625 7e27d576376ed37f92c23fe820478a6c 231 PIRSF PIRSF005624 11 231 2.2E-47 T 23-04-2016 DC74_RS35625 7e27d576376ed37f92c23fe820478a6c 231 PANTHER PTHR31715 24 231 3.8E-114 T 23-04-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 DC74_RS33265 0531c4f8b88a01c1d5172f73a5294fae 288 SUPERFAMILY SSF47413 12 71 3.22E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS33265 0531c4f8b88a01c1d5172f73a5294fae 288 PANTHER PTHR10245:SF20 9 288 5.0E-110 T 23-04-2016 DC74_RS33265 0531c4f8b88a01c1d5172f73a5294fae 288 Gene3D G3DSA:1.10.260.40 14 72 7.6E-10 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS33265 0531c4f8b88a01c1d5172f73a5294fae 288 PANTHER PTHR10245 9 288 5.0E-110 T 23-04-2016 DC74_RS33265 0531c4f8b88a01c1d5172f73a5294fae 288 SMART SM00530 20 75 6.7E-7 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS33265 0531c4f8b88a01c1d5172f73a5294fae 288 Pfam PF13560 Helix-turn-helix domain 17 73 4.1E-12 T 23-04-2016 DC74_RS35175 803358223caf3d5f1203bd532611ce22 259 Pfam PF07179 SseB protein N-terminal domain 96 196 1.8E-10 T 23-04-2016 IPR009839 SseB protein N-terminal domain DC74_RS14125 80cb8c273263ace9c75c67c555159e07 207 Gene3D G3DSA:3.40.30.10 72 165 3.6E-6 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS14125 80cb8c273263ace9c75c67c555159e07 207 Gene3D G3DSA:3.40.30.10 7 60 5.7E-6 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS14125 80cb8c273263ace9c75c67c555159e07 207 SUPERFAMILY SSF52833 6 167 5.43E-22 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS01155 16a480971a974ac89732ff859cbaf175 423 PANTHER PTHR11785 15 419 2.7E-101 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS01155 16a480971a974ac89732ff859cbaf175 423 Pfam PF13520 Amino acid permease 20 395 2.7E-42 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS01155 16a480971a974ac89732ff859cbaf175 423 PIRSF PIRSF006060 3 418 2.3E-66 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS01155 16a480971a974ac89732ff859cbaf175 423 PANTHER PTHR11785:SF366 15 419 2.7E-101 T 23-04-2016 DC74_RS10040 812c988c56899ba00e8b74d0c9d7fa9a 597 SUPERFAMILY SSF56235 64 195 7.72E-5 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS10040 812c988c56899ba00e8b74d0c9d7fa9a 597 Gene3D G3DSA:3.60.20.10 89 194 1.7E-6 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS10040 812c988c56899ba00e8b74d0c9d7fa9a 597 Gene3D G3DSA:3.40.50.620 446 572 2.0E-30 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS10040 812c988c56899ba00e8b74d0c9d7fa9a 597 Gene3D G3DSA:3.40.50.620 195 349 2.0E-30 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS10040 812c988c56899ba00e8b74d0c9d7fa9a 597 SUPERFAMILY SSF52402 203 353 9.49E-33 T 23-04-2016 DC74_RS10040 812c988c56899ba00e8b74d0c9d7fa9a 597 SUPERFAMILY SSF52402 450 580 9.49E-33 T 23-04-2016 DC74_RS10040 812c988c56899ba00e8b74d0c9d7fa9a 597 Pfam PF00733 Asparagine synthase 209 576 9.4E-43 T 23-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 DC74_RS16955 0e5807f1b7419287249cb23d57ba61b7 378 SUPERFAMILY SSF53697 67 375 3.71E-42 T 23-04-2016 DC74_RS16955 0e5807f1b7419287249cb23d57ba61b7 378 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 229 375 1.3E-17 T 23-04-2016 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 DC74_RS38285 9da1cb62fe131262086a267d519cd486 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 325 2.9E-31 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38285 9da1cb62fe131262086a267d519cd486 327 SUPERFAMILY SSF161098 189 308 4.14E-13 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38285 9da1cb62fe131262086a267d519cd486 327 SUPERFAMILY SSF161098 94 161 4.14E-13 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38285 9da1cb62fe131262086a267d519cd486 327 PANTHER PTHR30465 5 326 3.9E-75 T 23-04-2016 DC74_RS38285 9da1cb62fe131262086a267d519cd486 327 PANTHER PTHR30465:SF24 5 326 3.9E-75 T 23-04-2016 DC74_RS38285 9da1cb62fe131262086a267d519cd486 327 Gene3D G3DSA:1.10.3720.10 91 322 1.2E-11 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS35145 c85d29294781e65f2eee5b3eb1b62885 185 Gene3D G3DSA:3.90.960.10 25 179 1.7E-23 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 DC74_RS35145 c85d29294781e65f2eee5b3eb1b62885 185 PANTHER PTHR30411 3 180 5.0E-52 T 23-04-2016 DC74_RS35145 c85d29294781e65f2eee5b3eb1b62885 185 SUPERFAMILY SSF55826 47 179 2.22E-19 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 DC74_RS35145 c85d29294781e65f2eee5b3eb1b62885 185 Pfam PF04073 Aminoacyl-tRNA editing domain 48 170 3.6E-14 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 DC74_RS35145 c85d29294781e65f2eee5b3eb1b62885 185 PANTHER PTHR30411:SF1 3 180 5.0E-52 T 23-04-2016 DC74_RS25965 5c3c74192880f4c732cab8c6bc71f19a 266 PANTHER PTHR11941:SF76 3 263 4.0E-99 T 23-04-2016 DC74_RS25965 5c3c74192880f4c732cab8c6bc71f19a 266 PANTHER PTHR11941 3 263 4.0E-99 T 23-04-2016 DC74_RS25965 5c3c74192880f4c732cab8c6bc71f19a 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 265 2.3E-57 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS25965 5c3c74192880f4c732cab8c6bc71f19a 266 SUPERFAMILY SSF52096 2 266 1.61E-76 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS25965 5c3c74192880f4c732cab8c6bc71f19a 266 Gene3D G3DSA:3.90.226.10 2 263 1.7E-76 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS25965 5c3c74192880f4c732cab8c6bc71f19a 266 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 107 127 - T 23-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 DC74_RS02480 2f30995295cab353aafca8e57d755f16 281 SUPERFAMILY SSF53474 175 280 1.92E-28 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02480 2f30995295cab353aafca8e57d755f16 281 SUPERFAMILY SSF53474 9 146 1.92E-28 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02480 2f30995295cab353aafca8e57d755f16 281 PANTHER PTHR11614 9 144 1.6E-24 T 23-04-2016 DC74_RS02480 2f30995295cab353aafca8e57d755f16 281 Pfam PF12146 Serine aminopeptidase, S33 33 249 9.0E-28 T 23-04-2016 IPR022742 Serine aminopeptidase, S33 DC74_RS02480 2f30995295cab353aafca8e57d755f16 281 Gene3D G3DSA:3.40.50.1820 15 143 1.4E-25 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS02480 2f30995295cab353aafca8e57d755f16 281 Gene3D G3DSA:3.40.50.1820 192 279 1.4E-25 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS10155 59cfd519347ca61104fdcbf9c9fe5707 455 SUPERFAMILY SSF55931 122 453 1.18E-99 T 23-04-2016 DC74_RS10155 59cfd519347ca61104fdcbf9c9fe5707 455 SMART SM01230 120 373 3.8E-102 T 23-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS10155 59cfd519347ca61104fdcbf9c9fe5707 455 PANTHER PTHR20852 4 455 4.0E-190 T 23-04-2016 DC74_RS10155 59cfd519347ca61104fdcbf9c9fe5707 455 PANTHER PTHR20852:SF35 4 455 4.0E-190 T 23-04-2016 DC74_RS10155 59cfd519347ca61104fdcbf9c9fe5707 455 Gene3D G3DSA:3.10.20.70 11 123 1.9E-8 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS10155 59cfd519347ca61104fdcbf9c9fe5707 455 Pfam PF00120 Glutamine synthetase, catalytic domain 121 448 2.1E-101 T 23-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS10155 59cfd519347ca61104fdcbf9c9fe5707 455 SUPERFAMILY SSF54368 10 119 4.19E-15 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS10155 59cfd519347ca61104fdcbf9c9fe5707 455 Gene3D G3DSA:3.30.590.10 124 442 1.1E-97 T 23-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 DC74_RS26250 f4af19bbbd2fd4df31cbaba4ec754147 385 SUPERFAMILY SSF51735 39 342 1.53E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26250 f4af19bbbd2fd4df31cbaba4ec754147 385 Pfam PF01370 NAD dependent epimerase/dehydratase family 41 249 1.0E-15 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS26250 f4af19bbbd2fd4df31cbaba4ec754147 385 PANTHER PTHR10366 39 346 4.3E-51 T 23-04-2016 DC74_RS26250 f4af19bbbd2fd4df31cbaba4ec754147 385 Gene3D G3DSA:3.40.50.720 40 248 1.0E-26 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26250 f4af19bbbd2fd4df31cbaba4ec754147 385 PANTHER PTHR10366:SF124 39 346 4.3E-51 T 23-04-2016 DC74_RS08870 3c0712483296de7537407a17a6f6e5b0 344 Pfam PF13671 AAA domain 3 131 5.5E-10 T 23-04-2016 DC74_RS08870 3c0712483296de7537407a17a6f6e5b0 344 Gene3D G3DSA:3.90.79.10 200 318 9.7E-22 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS08870 3c0712483296de7537407a17a6f6e5b0 344 Gene3D G3DSA:3.40.50.300 2 183 1.2E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS08870 3c0712483296de7537407a17a6f6e5b0 344 SUPERFAMILY SSF55811 199 329 1.49E-22 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS08870 3c0712483296de7537407a17a6f6e5b0 344 SUPERFAMILY SSF52540 2 184 6.35E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS08870 3c0712483296de7537407a17a6f6e5b0 344 Pfam PF00293 NUDIX domain 200 324 6.4E-17 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS08870 3c0712483296de7537407a17a6f6e5b0 344 PRINTS PR00502 NUDIX hydrolase family signature 224 238 3.3E-6 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS08870 3c0712483296de7537407a17a6f6e5b0 344 PRINTS PR00502 NUDIX hydrolase family signature 238 253 3.3E-6 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS08870 3c0712483296de7537407a17a6f6e5b0 344 PANTHER PTHR22769 201 344 3.6E-39 T 23-04-2016 DC74_RS08870 3c0712483296de7537407a17a6f6e5b0 344 PANTHER PTHR22769:SF24 201 344 3.6E-39 T 23-04-2016 DC74_RS39010 c2143f136198007126221b8982a3215c 238 PANTHER PTHR19372 70 221 1.6E-47 T 23-04-2016 DC74_RS39010 c2143f136198007126221b8982a3215c 238 Pfam PF00174 Oxidoreductase molybdopterin binding domain 69 215 1.6E-36 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS39010 c2143f136198007126221b8982a3215c 238 Gene3D G3DSA:3.90.420.10 67 224 1.6E-49 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS39010 c2143f136198007126221b8982a3215c 238 SUPERFAMILY SSF56524 63 228 8.89E-52 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS18595 9bb84a78f0f53163337c9d009abedc77 154 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18595 9bb84a78f0f53163337c9d009abedc77 154 Pfam PF01196 Ribosomal protein L17 20 116 1.1E-38 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18595 9bb84a78f0f53163337c9d009abedc77 154 Gene3D G3DSA:3.90.1030.10 3 117 1.3E-48 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18595 9bb84a78f0f53163337c9d009abedc77 154 PANTHER PTHR14413:SF5 1 150 2.8E-62 T 23-04-2016 DC74_RS18595 9bb84a78f0f53163337c9d009abedc77 154 PANTHER PTHR14413 1 150 2.8E-62 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18595 9bb84a78f0f53163337c9d009abedc77 154 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 28.587 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18595 9bb84a78f0f53163337c9d009abedc77 154 SUPERFAMILY SSF64263 1 118 3.27E-48 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18595 9bb84a78f0f53163337c9d009abedc77 154 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 117 6.6E-43 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15900 c5812421636b031e2126aa383155ccee 194 PANTHER PTHR30055:SF33 1 190 7.9E-53 T 23-04-2016 DC74_RS15900 c5812421636b031e2126aa383155ccee 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.8E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS15900 c5812421636b031e2126aa383155ccee 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.8E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS15900 c5812421636b031e2126aa383155ccee 194 Gene3D G3DSA:1.10.10.60 8 62 5.5E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS15900 c5812421636b031e2126aa383155ccee 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.8E-16 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS15900 c5812421636b031e2126aa383155ccee 194 PANTHER PTHR30055 1 190 7.9E-53 T 23-04-2016 DC74_RS15900 c5812421636b031e2126aa383155ccee 194 SUPERFAMILY SSF46689 9 72 2.05E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS15900 c5812421636b031e2126aa383155ccee 194 SUPERFAMILY SSF48498 84 188 1.89E-8 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS15900 c5812421636b031e2126aa383155ccee 194 Gene3D G3DSA:1.10.357.10 63 192 8.0E-25 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS12635 0416f73cf135f3ed8e8e77667a362c77 206 Pfam PF13548 Domain of unknown function (DUF4126) 6 170 3.9E-45 T 23-04-2016 IPR025196 Domain of unknown function DUF4126 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 PANTHER PTHR11632 1 584 0.0 T 23-04-2016 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 Gene3D G3DSA:4.10.80.40 543 580 3.1E-18 T 23-04-2016 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 23-04-2016 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 Gene3D G3DSA:3.50.50.60 350 419 3.6E-113 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 Gene3D G3DSA:3.50.50.60 2 242 3.6E-113 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 SUPERFAMILY SSF56425 236 354 1.03E-42 T 23-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 Gene3D G3DSA:1.20.58.100 426 542 9.2E-43 T 23-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 385 2.4E-5 T 23-04-2016 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.4E-5 T 23-04-2016 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 363 385 1.2E-5 T 23-04-2016 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.2E-5 T 23-04-2016 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 584 5.1E-46 T 23-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 584 2.4E-247 T 23-04-2016 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 Pfam PF00890 FAD binding domain 7 400 1.1E-112 T 23-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 PIRSF PIRSF000171 1 578 3.3E-49 T 23-04-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 Gene3D G3DSA:3.90.700.10 243 349 2.5E-41 T 23-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 SUPERFAMILY SSF51905 2 259 1.78E-70 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 SUPERFAMILY SSF51905 358 432 1.78E-70 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 PANTHER PTHR11632:SF5 1 584 0.0 T 23-04-2016 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 SUPERFAMILY SSF46977 446 584 6.54E-51 T 23-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 DC74_RS24785 14ac087dfd59df07eca265ef8889e6db 584 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 584 7.3E-278 T 23-04-2016 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 DC74_RS30870 0d4a7cb8f40096981d3df60950291e8f 294 Pfam PF00296 Luciferase-like monooxygenase 11 232 2.4E-37 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS30870 0d4a7cb8f40096981d3df60950291e8f 294 SUPERFAMILY SSF51679 3 283 4.71E-50 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS30870 0d4a7cb8f40096981d3df60950291e8f 294 PANTHER PTHR30011 9 239 6.1E-51 T 23-04-2016 DC74_RS30870 0d4a7cb8f40096981d3df60950291e8f 294 Gene3D G3DSA:3.20.20.30 2 282 4.6E-56 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS30870 0d4a7cb8f40096981d3df60950291e8f 294 PANTHER PTHR30011:SF5 9 239 6.1E-51 T 23-04-2016 DC74_RS27565 964bf88316d1e1f5b2c3b57b468dcdda 130 Pfam PF12802 MarR family 23 80 1.9E-12 T 23-04-2016 DC74_RS27565 964bf88316d1e1f5b2c3b57b468dcdda 130 Gene3D G3DSA:1.10.10.10 4 126 3.4E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS27565 964bf88316d1e1f5b2c3b57b468dcdda 130 PANTHER PTHR33164 4 129 2.6E-17 T 23-04-2016 DC74_RS27565 964bf88316d1e1f5b2c3b57b468dcdda 130 SMART SM00347 18 114 7.5E-14 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS27565 964bf88316d1e1f5b2c3b57b468dcdda 130 PRINTS PR00598 Bacterial regulatory protein MarR family signature 40 56 1.3E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS27565 964bf88316d1e1f5b2c3b57b468dcdda 130 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 72 1.3E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS27565 964bf88316d1e1f5b2c3b57b468dcdda 130 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 92 1.3E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS27565 964bf88316d1e1f5b2c3b57b468dcdda 130 SUPERFAMILY SSF46785 5 126 1.35E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22455 5252bba0ac7a214221f8d15194483efe 581 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 218 527 1.2E-102 T 23-04-2016 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal DC74_RS22455 5252bba0ac7a214221f8d15194483efe 581 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 2 152 3.4E-13 T 23-04-2016 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 DC74_RS22455 5252bba0ac7a214221f8d15194483efe 581 PANTHER PTHR34697 6 578 2.8E-142 T 23-04-2016 DC74_RS22455 5252bba0ac7a214221f8d15194483efe 581 PANTHER PTHR34697:SF2 6 578 2.8E-142 T 23-04-2016 DC74_RS01650 6bc02694064fcefe48002c9f4fa38580 178 Pfam PF13671 AAA domain 1 136 4.5E-7 T 23-04-2016 DC74_RS01650 6bc02694064fcefe48002c9f4fa38580 178 Gene3D G3DSA:3.40.50.300 2 167 6.0E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS01650 6bc02694064fcefe48002c9f4fa38580 178 SUPERFAMILY SSF52540 2 166 2.61E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15255 9423eeaaa86cc7ac0c2a3876908c0b08 404 PANTHER PTHR30474 15 398 1.6E-141 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 DC74_RS15255 9423eeaaa86cc7ac0c2a3876908c0b08 404 Pfam PF01098 Cell cycle protein 38 397 3.4E-90 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 DC74_RS15255 9423eeaaa86cc7ac0c2a3876908c0b08 404 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 356 380 - T 23-04-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 DC74_RS15255 9423eeaaa86cc7ac0c2a3876908c0b08 404 PANTHER PTHR30474:SF1 15 398 1.6E-141 T 23-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 DC74_RS24260 2ba6cd388841d8198178fa7627a1ff81 474 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 21 449 7.5E-40 T 23-04-2016 IPR021145 Portal protein, SPP1 Gp6-like DC74_RS04920 67b53f55b496ecbcb6bf2e876877567c 578 SUPERFAMILY SSF90123 62 349 5.36E-22 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS04920 67b53f55b496ecbcb6bf2e876877567c 578 SUPERFAMILY SSF52540 364 577 8.36E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04920 67b53f55b496ecbcb6bf2e876877567c 578 Pfam PF00005 ABC transporter 384 530 6.3E-23 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS04920 67b53f55b496ecbcb6bf2e876877567c 578 SMART SM00382 393 576 7.2E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS04920 67b53f55b496ecbcb6bf2e876877567c 578 Gene3D G3DSA:3.40.50.300 368 577 1.3E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04920 67b53f55b496ecbcb6bf2e876877567c 578 PANTHER PTHR24222 76 578 6.1E-69 T 23-04-2016 DC74_RS04920 67b53f55b496ecbcb6bf2e876877567c 578 Gene3D G3DSA:1.20.1560.10 137 343 1.4E-12 T 23-04-2016 DC74_RS21005 df1c2ec2d646f67bf4885dafdb95a93e 122 Pfam PF04126 Cyclophilin-like 1 119 5.0E-36 T 23-04-2016 IPR025658 Cyclophilin TM1367-like domain DC74_RS21005 df1c2ec2d646f67bf4885dafdb95a93e 122 SUPERFAMILY SSF50891 1 121 1.9E-27 T 23-04-2016 IPR029000 Cyclophilin-like domain DC74_RS28490 49b385e7936400d843972f6d7e645bba 96 Gene3D G3DSA:1.10.287.1060 4 96 4.7E-26 T 23-04-2016 DC74_RS28490 49b385e7936400d843972f6d7e645bba 96 SUPERFAMILY SSF140453 3 95 2.75E-23 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS28490 49b385e7936400d843972f6d7e645bba 96 Pfam PF06013 Proteins of 100 residues with WXG 4 89 1.3E-18 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS28490 49b385e7936400d843972f6d7e645bba 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 93 7.4E-22 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS18170 bbaf8ab74ee7231555d0cd38090e307e 482 SMART SM00481 168 232 0.003 T 23-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 DC74_RS18170 bbaf8ab74ee7231555d0cd38090e307e 482 Gene3D G3DSA:3.20.20.140 165 342 9.8E-14 T 23-04-2016 DC74_RS18170 bbaf8ab74ee7231555d0cd38090e307e 482 SUPERFAMILY SSF89550 165 371 8.11E-32 T 23-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 DC74_RS37250 63244b124da135bedc916db2e1a27be9 296 Pfam PF02219 Methylenetetrahydrofolate reductase 13 283 6.2E-93 T 23-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 DC74_RS37250 63244b124da135bedc916db2e1a27be9 296 PANTHER PTHR21091:SF31 146 281 1.2E-29 T 23-04-2016 DC74_RS37250 63244b124da135bedc916db2e1a27be9 296 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 15 286 9.4E-96 T 23-04-2016 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 DC74_RS37250 63244b124da135bedc916db2e1a27be9 296 Gene3D G3DSA:3.20.20.220 3 286 4.4E-96 T 23-04-2016 IPR029041 FAD-linked oxidoreductase-like DC74_RS37250 63244b124da135bedc916db2e1a27be9 296 PANTHER PTHR21091 146 281 1.2E-29 T 23-04-2016 DC74_RS37250 63244b124da135bedc916db2e1a27be9 296 SUPERFAMILY SSF51730 5 284 9.81E-87 T 23-04-2016 IPR029041 FAD-linked oxidoreductase-like DC74_RS28835 a58a502810a382bc78fe805861e329ca 330 Gene3D G3DSA:3.40.190.10 262 325 6.3E-27 T 23-04-2016 DC74_RS28835 a58a502810a382bc78fe805861e329ca 330 Gene3D G3DSA:3.40.190.10 41 120 6.3E-27 T 23-04-2016 DC74_RS28835 a58a502810a382bc78fe805861e329ca 330 Pfam PF16868 NMT1-like family 44 325 7.3E-46 T 23-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family DC74_RS28835 a58a502810a382bc78fe805861e329ca 330 PANTHER PTHR30024:SF5 2 325 6.5E-48 T 23-04-2016 DC74_RS28835 a58a502810a382bc78fe805861e329ca 330 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 10 327 1.8E-70 T 23-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family DC74_RS28835 a58a502810a382bc78fe805861e329ca 330 PANTHER PTHR30024 2 325 6.5E-48 T 23-04-2016 DC74_RS28835 a58a502810a382bc78fe805861e329ca 330 Gene3D G3DSA:3.40.190.10 124 261 3.3E-29 T 23-04-2016 DC74_RS28835 a58a502810a382bc78fe805861e329ca 330 SUPERFAMILY SSF53850 40 325 9.59E-52 T 23-04-2016 DC74_RS14695 3583ca1fbf7f48bb14b1e548c5a43a26 288 SMART SM00530 31 88 8.8E-5 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS14695 3583ca1fbf7f48bb14b1e548c5a43a26 288 Gene3D G3DSA:1.10.260.40 25 69 9.7E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS14695 3583ca1fbf7f48bb14b1e548c5a43a26 288 SUPERFAMILY SSF47413 22 69 3.94E-8 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS14695 3583ca1fbf7f48bb14b1e548c5a43a26 288 PANTHER PTHR10245:SF7 2 287 4.9E-47 T 23-04-2016 DC74_RS14695 3583ca1fbf7f48bb14b1e548c5a43a26 288 Pfam PF13560 Helix-turn-helix domain 27 70 8.2E-8 T 23-04-2016 DC74_RS14695 3583ca1fbf7f48bb14b1e548c5a43a26 288 PANTHER PTHR10245 2 287 4.9E-47 T 23-04-2016 DC74_RS28420 9589cfbec936869582b7a58e7a670f05 190 SUPERFAMILY SSF75420 3 85 1.57E-19 T 23-04-2016 IPR028989 Ribosome maturation factor RimP, N-terminal DC74_RS28420 9589cfbec936869582b7a58e7a670f05 190 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 155 22.905 T 23-04-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 DC74_RS28420 9589cfbec936869582b7a58e7a670f05 190 Gene3D G3DSA:3.30.300.70 3 82 9.3E-24 T 23-04-2016 IPR028989 Ribosome maturation factor RimP, N-terminal DC74_RS28420 9589cfbec936869582b7a58e7a670f05 190 PANTHER PTHR33867 1 158 9.4E-42 T 23-04-2016 DC74_RS28420 9589cfbec936869582b7a58e7a670f05 190 PANTHER PTHR33867:SF1 1 158 9.4E-42 T 23-04-2016 DC74_RS28420 9589cfbec936869582b7a58e7a670f05 190 SUPERFAMILY SSF74942 86 155 5.89E-5 T 23-04-2016 IPR028998 Ribosome maturation factor RimP, C-terminal DC74_RS28420 9589cfbec936869582b7a58e7a670f05 190 Pfam PF02576 Putative ribosome maturation factor RimP 12 151 4.8E-35 T 23-04-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 DC74_RS17005 addb82003a60130eca93c0aff853a9d8 301 SUPERFAMILY SSF48150 103 281 3.66E-29 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS17005 addb82003a60130eca93c0aff853a9d8 301 Gene3D G3DSA:1.10.340.30 117 230 4.2E-19 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS30940 315a9856cd9d8396354f57f4de9c5033 255 Gene3D G3DSA:3.40.50.1820 2 208 6.2E-41 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS30940 315a9856cd9d8396354f57f4de9c5033 255 Pfam PF01764 Lipase (class 3) 55 187 1.7E-27 T 23-04-2016 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: REACT_14797|Reactome: REACT_604 DC74_RS30940 315a9856cd9d8396354f57f4de9c5033 255 PANTHER PTHR21493:SF153 51 194 4.1E-33 T 23-04-2016 DC74_RS30940 315a9856cd9d8396354f57f4de9c5033 255 SUPERFAMILY SSF53474 42 215 1.17E-31 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS30940 315a9856cd9d8396354f57f4de9c5033 255 PANTHER PTHR21493 51 194 4.1E-33 T 23-04-2016 DC74_RS03890 1ba8f69221f32e0a517b03455e16a5f8 144 Gene3D G3DSA:2.30.110.10 8 142 1.3E-33 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS03890 1ba8f69221f32e0a517b03455e16a5f8 144 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 17 139 9.4E-26 T 23-04-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related DC74_RS03890 1ba8f69221f32e0a517b03455e16a5f8 144 SUPERFAMILY SSF50475 14 141 9.49E-16 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS29100 1c1e7f65cf1742d59566a7fa89df551b 257 SUPERFAMILY SSF54593 143 255 1.14E-16 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS29100 1c1e7f65cf1742d59566a7fa89df551b 257 SUPERFAMILY SSF54593 14 126 3.62E-15 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS29100 1c1e7f65cf1742d59566a7fa89df551b 257 Gene3D G3DSA:3.10.180.10 14 127 2.3E-28 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS29100 1c1e7f65cf1742d59566a7fa89df551b 257 Gene3D G3DSA:3.10.180.10 141 256 3.1E-28 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS29100 1c1e7f65cf1742d59566a7fa89df551b 257 PANTHER PTHR33993 7 257 2.4E-100 T 23-04-2016 DC74_RS29100 1c1e7f65cf1742d59566a7fa89df551b 257 PANTHER PTHR33993:SF3 7 257 2.4E-100 T 23-04-2016 DC74_RS38435 8058c51e77648ab1ff85084eea70d0a0 239 SUPERFAMILY SSF46689 13 89 2.48E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS38435 8058c51e77648ab1ff85084eea70d0a0 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 9.4E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS38435 8058c51e77648ab1ff85084eea70d0a0 239 PANTHER PTHR30055 8 99 5.6E-16 T 23-04-2016 DC74_RS38435 8058c51e77648ab1ff85084eea70d0a0 239 PANTHER PTHR30055:SF74 8 99 5.6E-16 T 23-04-2016 DC74_RS38435 8058c51e77648ab1ff85084eea70d0a0 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.5E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS38435 8058c51e77648ab1ff85084eea70d0a0 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.5E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS38435 8058c51e77648ab1ff85084eea70d0a0 239 Gene3D G3DSA:1.10.357.10 8 236 3.8E-17 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS21015 4b6b0ffb15a2641d4a72a83027505ddc 333 PANTHER PTHR30365:SF6 1 333 3.7E-135 T 23-04-2016 DC74_RS21015 4b6b0ffb15a2641d4a72a83027505ddc 333 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 2 217 1.3E-75 T 23-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 DC74_RS21015 4b6b0ffb15a2641d4a72a83027505ddc 333 PANTHER PTHR30365 1 333 3.7E-135 T 23-04-2016 DC74_RS21015 4b6b0ffb15a2641d4a72a83027505ddc 333 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 7.3E-115 T 23-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 DC74_RS21015 4b6b0ffb15a2641d4a72a83027505ddc 333 PIRSF PIRSF000267 1 333 1.2E-121 T 23-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 DC74_RS04150 75a95170c123753db8316a9cce476e65 190 Gene3D G3DSA:3.40.630.30 2 183 8.5E-48 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS04150 75a95170c123753db8316a9cce476e65 190 Pfam PF13302 Acetyltransferase (GNAT) domain 9 151 1.8E-30 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS04150 75a95170c123753db8316a9cce476e65 190 PANTHER PTHR13256 1 190 2.2E-38 T 23-04-2016 DC74_RS04150 75a95170c123753db8316a9cce476e65 190 SUPERFAMILY SSF55729 2 170 4.16E-38 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS04150 75a95170c123753db8316a9cce476e65 190 PANTHER PTHR13256:SF10 1 190 2.2E-38 T 23-04-2016 DC74_RS19565 c63efb9d0dc65fa45ed0d0acbb66a2d1 415 PANTHER PTHR13847 7 399 8.1E-131 T 23-04-2016 DC74_RS19565 c63efb9d0dc65fa45ed0d0acbb66a2d1 415 Gene3D G3DSA:3.50.50.60 142 220 2.2E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19565 c63efb9d0dc65fa45ed0d0acbb66a2d1 415 Gene3D G3DSA:3.50.50.60 5 88 2.2E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19565 c63efb9d0dc65fa45ed0d0acbb66a2d1 415 PANTHER PTHR13847:SF191 7 399 8.1E-131 T 23-04-2016 DC74_RS19565 c63efb9d0dc65fa45ed0d0acbb66a2d1 415 Pfam PF01266 FAD dependent oxidoreductase 7 395 2.8E-66 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DC74_RS19565 c63efb9d0dc65fa45ed0d0acbb66a2d1 415 SUPERFAMILY SSF51905 5 305 4.86E-46 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS19565 c63efb9d0dc65fa45ed0d0acbb66a2d1 415 Gene3D G3DSA:3.30.9.10 222 228 2.8E-7 T 23-04-2016 DC74_RS19565 c63efb9d0dc65fa45ed0d0acbb66a2d1 415 Gene3D G3DSA:3.30.9.10 91 141 2.8E-7 T 23-04-2016 DC74_RS25835 2b38dccaceed2861e1e18023871a9ac3 378 Gene3D G3DSA:3.40.50.300 20 274 1.4E-81 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25835 2b38dccaceed2861e1e18023871a9ac3 378 SUPERFAMILY SSF52540 22 271 1.74E-74 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25835 2b38dccaceed2861e1e18023871a9ac3 378 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS25835 2b38dccaceed2861e1e18023871a9ac3 378 Pfam PF00005 ABC transporter 50 200 5.1E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS25835 2b38dccaceed2861e1e18023871a9ac3 378 SMART SM00382 58 250 4.2E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS25835 2b38dccaceed2861e1e18023871a9ac3 378 PANTHER PTHR24220 23 368 5.6E-167 T 23-04-2016 DC74_RS25835 2b38dccaceed2861e1e18023871a9ac3 378 PANTHER PTHR24220:SF336 23 368 5.6E-167 T 23-04-2016 DC74_RS25835 2b38dccaceed2861e1e18023871a9ac3 378 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 250 344 2.0E-27 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS25835 2b38dccaceed2861e1e18023871a9ac3 378 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 252 321 3.8E-17 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS33065 8b7c86242f35a07f5f75d4059902613c 293 PANTHER PTHR36124:SF2 1 252 1.7E-59 T 23-04-2016 DC74_RS33065 8b7c86242f35a07f5f75d4059902613c 293 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 66 247 6.3E-11 T 23-04-2016 IPR018713 Domain of unknown function DUF2236 DC74_RS33065 8b7c86242f35a07f5f75d4059902613c 293 PANTHER PTHR36124 1 252 1.7E-59 T 23-04-2016 DC74_RS02205 5726100f73a8b5aca659d00b41d998a4 150 SUPERFAMILY SSF54593 8 32 1.32E-8 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS02205 5726100f73a8b5aca659d00b41d998a4 150 SUPERFAMILY SSF54593 65 148 1.32E-8 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS02205 5726100f73a8b5aca659d00b41d998a4 150 PANTHER PTHR35908:SF1 1 32 3.2E-31 T 23-04-2016 DC74_RS02205 5726100f73a8b5aca659d00b41d998a4 150 PANTHER PTHR35908:SF1 66 148 3.2E-31 T 23-04-2016 DC74_RS02205 5726100f73a8b5aca659d00b41d998a4 150 PANTHER PTHR35908 1 32 3.2E-31 T 23-04-2016 DC74_RS02205 5726100f73a8b5aca659d00b41d998a4 150 PANTHER PTHR35908 66 148 3.2E-31 T 23-04-2016 DC74_RS02205 5726100f73a8b5aca659d00b41d998a4 150 Gene3D G3DSA:3.10.180.10 9 150 2.6E-7 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS36560 bf1b0ce43756f936ef95f0a91845ac17 238 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 218 1.7E-27 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS36560 bf1b0ce43756f936ef95f0a91845ac17 238 Gene3D G3DSA:1.20.120.450 10 133 4.2E-9 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS36560 bf1b0ce43756f936ef95f0a91845ac17 238 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 14 150 1.1E-22 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS36560 bf1b0ce43756f936ef95f0a91845ac17 238 SUPERFAMILY SSF55718 160 237 1.65E-10 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS36560 bf1b0ce43756f936ef95f0a91845ac17 238 SUPERFAMILY SSF109854 7 156 2.75E-34 T 23-04-2016 DC74_RS00600 e0f034fbf4807d2168e0a3b2700a49d1 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 1.6E-7 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS00600 e0f034fbf4807d2168e0a3b2700a49d1 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 1.6E-7 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS00600 e0f034fbf4807d2168e0a3b2700a49d1 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 1.6E-7 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS00600 e0f034fbf4807d2168e0a3b2700a49d1 285 Gene3D G3DSA:3.40.50.1820 10 280 3.6E-52 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS00600 e0f034fbf4807d2168e0a3b2700a49d1 285 SUPERFAMILY SSF53474 10 280 4.4E-52 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS00600 e0f034fbf4807d2168e0a3b2700a49d1 285 PANTHER PTHR10992 181 281 6.7E-73 T 23-04-2016 DC74_RS00600 e0f034fbf4807d2168e0a3b2700a49d1 285 PANTHER PTHR10992 9 146 6.7E-73 T 23-04-2016 DC74_RS00600 e0f034fbf4807d2168e0a3b2700a49d1 285 PANTHER PTHR10992:SF884 181 281 6.7E-73 T 23-04-2016 DC74_RS00600 e0f034fbf4807d2168e0a3b2700a49d1 285 PANTHER PTHR10992:SF884 9 146 6.7E-73 T 23-04-2016 DC74_RS00600 e0f034fbf4807d2168e0a3b2700a49d1 285 Pfam PF00561 alpha/beta hydrolase fold 28 131 9.3E-19 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS16660 a39c7590c1f4c208406151ec6d1138e1 340 SUPERFAMILY SSF46785 4 85 3.25E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16660 a39c7590c1f4c208406151ec6d1138e1 340 Gene3D G3DSA:1.10.10.10 5 84 1.8E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS16660 a39c7590c1f4c208406151ec6d1138e1 340 Gene3D G3DSA:3.40.190.10 134 179 4.1E-7 T 23-04-2016 DC74_RS16660 a39c7590c1f4c208406151ec6d1138e1 340 Pfam PF03466 LysR substrate binding domain 97 296 5.9E-12 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS16660 a39c7590c1f4c208406151ec6d1138e1 340 Gene3D G3DSA:3.40.190.10 180 271 7.3E-5 T 23-04-2016 DC74_RS16660 a39c7590c1f4c208406151ec6d1138e1 340 SUPERFAMILY SSF53850 96 301 7.12E-14 T 23-04-2016 DC74_RS16660 a39c7590c1f4c208406151ec6d1138e1 340 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 8.7E-20 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS16660 a39c7590c1f4c208406151ec6d1138e1 340 PANTHER PTHR30346:SF7 4 314 2.7E-84 T 23-04-2016 DC74_RS16660 a39c7590c1f4c208406151ec6d1138e1 340 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.1E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS16660 a39c7590c1f4c208406151ec6d1138e1 340 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.1E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS16660 a39c7590c1f4c208406151ec6d1138e1 340 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.1E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS16660 a39c7590c1f4c208406151ec6d1138e1 340 PANTHER PTHR30346 4 314 2.7E-84 T 23-04-2016 DC74_RS19230 46f1c61fa1bef441c6198bba75fa74db 249 PANTHER PTHR30108 25 73 2.4E-65 T 23-04-2016 DC74_RS19230 46f1c61fa1bef441c6198bba75fa74db 249 PANTHER PTHR30108 102 239 2.4E-65 T 23-04-2016 DC74_RS19230 46f1c61fa1bef441c6198bba75fa74db 249 Gene3D G3DSA:3.40.50.1950 27 236 7.0E-64 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS19230 46f1c61fa1bef441c6198bba75fa74db 249 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 110 233 4.1E-34 T 23-04-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 DC74_RS19230 46f1c61fa1bef441c6198bba75fa74db 249 SUPERFAMILY SSF52507 110 235 8.37E-45 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS19230 46f1c61fa1bef441c6198bba75fa74db 249 SUPERFAMILY SSF52507 27 83 8.37E-45 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS19230 46f1c61fa1bef441c6198bba75fa74db 249 PANTHER PTHR30108:SF2 102 239 2.4E-65 T 23-04-2016 DC74_RS19230 46f1c61fa1bef441c6198bba75fa74db 249 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 26 235 29.957 T 23-04-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 DC74_RS19230 46f1c61fa1bef441c6198bba75fa74db 249 Pfam PF02441 Flavoprotein 28 177 4.4E-23 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 DC74_RS19230 46f1c61fa1bef441c6198bba75fa74db 249 PANTHER PTHR30108:SF2 25 73 2.4E-65 T 23-04-2016 DC74_RS24935 9f48cdee334885d187acdd08e99e66d9 428 PANTHER PTHR32196:SF40 380 427 4.9E-97 T 23-04-2016 DC74_RS24935 9f48cdee334885d187acdd08e99e66d9 428 PANTHER PTHR32196:SF40 17 191 4.9E-97 T 23-04-2016 DC74_RS24935 9f48cdee334885d187acdd08e99e66d9 428 PANTHER PTHR32196 218 330 4.9E-97 T 23-04-2016 DC74_RS24935 9f48cdee334885d187acdd08e99e66d9 428 PANTHER PTHR32196:SF40 218 330 4.9E-97 T 23-04-2016 DC74_RS24935 9f48cdee334885d187acdd08e99e66d9 428 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 334 4.1E-27 T 23-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 DC74_RS24935 9f48cdee334885d187acdd08e99e66d9 428 PANTHER PTHR32196 17 191 4.9E-97 T 23-04-2016 DC74_RS24935 9f48cdee334885d187acdd08e99e66d9 428 PANTHER PTHR32196 380 427 4.9E-97 T 23-04-2016 DC74_RS12875 e0ec53e5f5549b981e33330e4d68f36e 458 SUPERFAMILY SSF53383 36 436 5.09E-82 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS12875 e0ec53e5f5549b981e33330e4d68f36e 458 Gene3D G3DSA:3.40.640.10 53 294 4.6E-65 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS12875 e0ec53e5f5549b981e33330e4d68f36e 458 PANTHER PTHR11601 37 448 2.9E-164 T 23-04-2016 DC74_RS12875 e0ec53e5f5549b981e33330e4d68f36e 458 Pfam PF00266 Aminotransferase class-V 37 428 1.1E-75 T 23-04-2016 IPR000192 Aminotransferase class V domain DC74_RS12875 e0ec53e5f5549b981e33330e4d68f36e 458 PANTHER PTHR11601:SF40 37 448 2.9E-164 T 23-04-2016 DC74_RS12875 e0ec53e5f5549b981e33330e4d68f36e 458 Gene3D G3DSA:3.90.1150.10 410 435 8.8E-15 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS12875 e0ec53e5f5549b981e33330e4d68f36e 458 Gene3D G3DSA:3.90.1150.10 295 378 8.8E-15 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS10980 89ff74f0b01a49fda79572df1a24e961 423 Pfam PF00534 Glycosyl transferases group 1 201 355 7.3E-30 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 DC74_RS10980 89ff74f0b01a49fda79572df1a24e961 423 SUPERFAMILY SSF53756 4 378 4.71E-58 T 23-04-2016 DC74_RS10980 89ff74f0b01a49fda79572df1a24e961 423 PANTHER PTHR12526 90 418 7.3E-45 T 23-04-2016 DC74_RS10980 89ff74f0b01a49fda79572df1a24e961 423 PANTHER PTHR12526 1 60 7.3E-45 T 23-04-2016 DC74_RS10980 89ff74f0b01a49fda79572df1a24e961 423 Gene3D G3DSA:3.40.50.2000 198 355 2.5E-20 T 23-04-2016 DC74_RS10980 89ff74f0b01a49fda79572df1a24e961 423 PANTHER PTHR12526:SF374 90 418 7.3E-45 T 23-04-2016 DC74_RS10980 89ff74f0b01a49fda79572df1a24e961 423 PANTHER PTHR12526:SF374 1 60 7.3E-45 T 23-04-2016 DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 SUPERFAMILY SSF52540 284 522 2.49E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 Gene3D G3DSA:3.40.50.300 13 251 2.2E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 SUPERFAMILY SSF52540 11 249 1.07E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 Pfam PF00005 ABC transporter 30 197 2.0E-25 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 Pfam PF00005 ABC transporter 308 461 7.4E-18 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 ProSitePatterns PS00211 ABC transporters family signature. 434 448 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 PANTHER PTHR24220 16 73 1.3E-180 T 23-04-2016 DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 PANTHER PTHR24220 94 416 1.3E-180 T 23-04-2016 DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 SMART SM00382 316 510 3.0E-4 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 SMART SM00382 39 245 3.5E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 PANTHER PTHR24220:SF502 16 73 1.3E-180 T 23-04-2016 DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 PANTHER PTHR24220:SF502 94 416 1.3E-180 T 23-04-2016 DC74_RS14100 35994470671f77bd6918599d5f8dba7b 553 Gene3D G3DSA:3.40.50.300 277 524 2.3E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS08490 05370b5146b78911a0573548f9cce3d0 78 Pfam PF17196 Protein of unknown function (DUF5133) 1 65 1.6E-28 T 23-04-2016 IPR033457 Protein of unknown function DUF5133 DC74_RS36295 ced1bba607131160b0cb13f8e80b6844 375 Pfam PF00296 Luciferase-like monooxygenase 18 338 7.1E-48 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS36295 ced1bba607131160b0cb13f8e80b6844 375 SUPERFAMILY SSF51679 3 369 1.96E-72 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS36295 ced1bba607131160b0cb13f8e80b6844 375 Gene3D G3DSA:3.20.20.30 2 369 1.1E-87 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS36295 ced1bba607131160b0cb13f8e80b6844 375 PANTHER PTHR30137 17 375 5.0E-49 T 23-04-2016 DC74_RS11890 abaa6dd2efc51040e30720b5496f5767 319 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 23-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 DC74_RS11890 abaa6dd2efc51040e30720b5496f5767 319 SUPERFAMILY SSF53613 2 313 1.56E-59 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS11890 abaa6dd2efc51040e30720b5496f5767 319 Pfam PF00294 pfkB family carbohydrate kinase 2 311 1.7E-43 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS11890 abaa6dd2efc51040e30720b5496f5767 319 Gene3D G3DSA:3.40.1190.20 2 317 6.0E-63 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS11890 abaa6dd2efc51040e30720b5496f5767 319 PANTHER PTHR10584 2 312 1.2E-69 T 23-04-2016 DC74_RS11890 abaa6dd2efc51040e30720b5496f5767 319 PANTHER PTHR10584:SF161 2 312 1.2E-69 T 23-04-2016 DC74_RS34330 86a18faeb7e14dd03cb9f256a7f7ea9a 287 Gene3D G3DSA:3.40.50.1400 23 150 8.5E-4 T 23-04-2016 DC74_RS32480 1d6cadeef0df3f3d15e45df76ed3b6b1 332 SUPERFAMILY SSF103481 55 154 3.92E-13 T 23-04-2016 DC74_RS32480 1d6cadeef0df3f3d15e45df76ed3b6b1 332 PANTHER PTHR12715:SF4 14 304 1.5E-84 T 23-04-2016 DC74_RS32480 1d6cadeef0df3f3d15e45df76ed3b6b1 332 SUPERFAMILY SSF103481 203 300 2.09E-14 T 23-04-2016 DC74_RS32480 1d6cadeef0df3f3d15e45df76ed3b6b1 332 PANTHER PTHR12715 14 304 1.5E-84 T 23-04-2016 DC74_RS32480 1d6cadeef0df3f3d15e45df76ed3b6b1 332 Pfam PF00892 EamA-like transporter family 163 296 2.1E-22 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS32480 1d6cadeef0df3f3d15e45df76ed3b6b1 332 Pfam PF00892 EamA-like transporter family 22 150 9.1E-19 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS17845 552db89a9d6c09902c87f240ad91c9e0 300 PANTHER PTHR22572 10 298 2.8E-94 T 23-04-2016 DC74_RS17845 552db89a9d6c09902c87f240ad91c9e0 300 PANTHER PTHR22572:SF14 10 298 2.8E-94 T 23-04-2016 DC74_RS17845 552db89a9d6c09902c87f240ad91c9e0 300 SUPERFAMILY SSF53448 10 290 2.92E-62 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS17845 552db89a9d6c09902c87f240ad91c9e0 300 Gene3D G3DSA:3.90.550.10 10 282 1.1E-72 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS17845 552db89a9d6c09902c87f240ad91c9e0 300 Pfam PF00483 Nucleotidyl transferase 10 273 6.7E-25 T 23-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 DC74_RS17845 552db89a9d6c09902c87f240ad91c9e0 300 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 273 2.8E-102 T 23-04-2016 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 DC74_RS03780 3953230cefd9d5927b5ff93da1b1f73f 258 PANTHER PTHR10108 189 213 2.8E-23 T 23-04-2016 DC74_RS03780 3953230cefd9d5927b5ff93da1b1f73f 258 Pfam PF08241 Methyltransferase domain 40 126 2.3E-14 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS03780 3953230cefd9d5927b5ff93da1b1f73f 258 SUPERFAMILY SSF53335 2 193 1.09E-28 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS03780 3953230cefd9d5927b5ff93da1b1f73f 258 Gene3D G3DSA:3.40.50.150 2 131 7.4E-28 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS03780 3953230cefd9d5927b5ff93da1b1f73f 258 PANTHER PTHR10108:SF730 189 213 2.8E-23 T 23-04-2016 DC74_RS03780 3953230cefd9d5927b5ff93da1b1f73f 258 PANTHER PTHR10108 1 151 2.8E-23 T 23-04-2016 DC74_RS03780 3953230cefd9d5927b5ff93da1b1f73f 258 PANTHER PTHR10108:SF730 1 151 2.8E-23 T 23-04-2016 DC74_RS14045 436c42e7f0ca7ceded6b3aa49323f28e 428 Gene3D G3DSA:3.40.47.10 277 427 1.4E-47 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS14045 436c42e7f0ca7ceded6b3aa49323f28e 428 SMART SM00825 Beta-ketoacyl synthase 8 419 6.8E-13 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS14045 436c42e7f0ca7ceded6b3aa49323f28e 428 PIRSF PIRSF000447 3 428 1.0E-137 T 23-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 DC74_RS14045 436c42e7f0ca7ceded6b3aa49323f28e 428 SUPERFAMILY SSF53901 6 265 2.76E-65 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS14045 436c42e7f0ca7ceded6b3aa49323f28e 428 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 260 9.1E-52 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS14045 436c42e7f0ca7ceded6b3aa49323f28e 428 PANTHER PTHR11712 5 426 7.7E-155 T 23-04-2016 DC74_RS14045 436c42e7f0ca7ceded6b3aa49323f28e 428 Gene3D G3DSA:3.40.47.10 10 271 4.4E-66 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS14045 436c42e7f0ca7ceded6b3aa49323f28e 428 SUPERFAMILY SSF53901 227 427 2.27E-61 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS14045 436c42e7f0ca7ceded6b3aa49323f28e 428 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 268 382 1.3E-31 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS22865 81f8da870251b73b502108d9792d059b 278 PANTHER PTHR11487 21 278 1.4E-71 T 23-04-2016 IPR012223 Thioesterase type II, NRPS/PKS/S-FAS GO:0009058 DC74_RS22865 81f8da870251b73b502108d9792d059b 278 Gene3D G3DSA:3.40.50.1820 19 265 2.9E-35 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS22865 81f8da870251b73b502108d9792d059b 278 SMART SM00824 Thioesterase 41 265 0.0013 T 23-04-2016 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 DC74_RS22865 81f8da870251b73b502108d9792d059b 278 PANTHER PTHR11487:SF3 21 278 1.4E-71 T 23-04-2016 DC74_RS22865 81f8da870251b73b502108d9792d059b 278 Pfam PF00975 Thioesterase domain 39 264 9.9E-48 T 23-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 DC74_RS22865 81f8da870251b73b502108d9792d059b 278 SUPERFAMILY SSF53474 12 266 1.8E-50 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS26115 e60f27137e39dee105341f7c4cf3957c 319 PANTHER PTHR30465 10 299 2.2E-91 T 23-04-2016 DC74_RS26115 e60f27137e39dee105341f7c4cf3957c 319 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 9 48 2.7E-6 T 23-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain DC74_RS26115 e60f27137e39dee105341f7c4cf3957c 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 298 2.9E-24 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26115 e60f27137e39dee105341f7c4cf3957c 319 PANTHER PTHR30465:SF69 10 299 2.2E-91 T 23-04-2016 DC74_RS26115 e60f27137e39dee105341f7c4cf3957c 319 Gene3D G3DSA:1.10.3720.10 87 295 5.1E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26115 e60f27137e39dee105341f7c4cf3957c 319 SUPERFAMILY SSF161098 89 285 3.66E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS40765 a79777afb653b45d1a3dbda334cb266f 92 Pfam PF01526 Tn3 transposase DDE domain 2 55 2.0E-14 T 23-04-2016 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 DC74_RS25415 134f890da7c9faf8cbb8aad58de1833a 446 Pfam PF00437 Type II/IV secretion system protein 86 362 3.3E-86 T 23-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 DC74_RS25415 134f890da7c9faf8cbb8aad58de1833a 446 SUPERFAMILY SSF52540 67 391 8.48E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25415 134f890da7c9faf8cbb8aad58de1833a 446 Gene3D G3DSA:3.40.50.300 185 394 5.9E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25415 134f890da7c9faf8cbb8aad58de1833a 446 Gene3D G3DSA:3.30.450.90 83 180 1.5E-38 T 23-04-2016 DC74_RS25415 134f890da7c9faf8cbb8aad58de1833a 446 PANTHER PTHR30258:SF3 26 390 6.1E-122 T 23-04-2016 DC74_RS25415 134f890da7c9faf8cbb8aad58de1833a 446 PANTHER PTHR30258 26 390 6.1E-122 T 23-04-2016 DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 Pfam PF10397 Adenylosuccinate lyase C-terminus 365 437 3.7E-8 T 23-04-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 PANTHER PTHR11444:SF2 7 456 2.1E-117 T 23-04-2016 DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 SMART SM00998 361 441 1.3E-9 T 23-04-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 Gene3D G3DSA:1.20.200.10 99 370 3.1E-82 T 23-04-2016 DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 5.6E-5 T 23-04-2016 DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 PRINTS PR00145 Argininosuccinate lyase family signature 273 289 5.6E-5 T 23-04-2016 DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 SUPERFAMILY SSF48557 6 446 2.04E-112 T 23-04-2016 IPR008948 L-Aspartase-like GO:0003824 DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 Gene3D G3DSA:1.10.275.10 7 98 1.4E-26 T 23-04-2016 IPR024083 Fumarase/histidase, N-terminal DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 Gene3D G3DSA:1.10.40.30 371 439 9.5E-11 T 23-04-2016 DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 ProSitePatterns PS00163 Fumarate lyases signature. 273 282 - T 23-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 7 426 2.0E-123 T 23-04-2016 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 Pfam PF00206 Lyase 13 293 7.5E-45 T 23-04-2016 IPR022761 Fumarate lyase, N-terminal DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 PRINTS PR00149 Fumarate lyase superfamily signature 273 289 1.7E-26 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 1.7E-26 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 1.7E-26 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 1.7E-26 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS32605 ae571b05099c1079156a57f8d5628273 461 PANTHER PTHR11444 7 456 2.1E-117 T 23-04-2016 IPR000362 Fumarate lyase family DC74_RS38395 63d793cfea1220e77f4a0da5f9b8fb50 204 PANTHER PTHR30328:SF7 8 194 9.9E-38 T 23-04-2016 DC74_RS38395 63d793cfea1220e77f4a0da5f9b8fb50 204 SUPERFAMILY SSF48498 84 195 7.71E-18 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS38395 63d793cfea1220e77f4a0da5f9b8fb50 204 Gene3D G3DSA:1.10.10.60 4 59 1.1E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS38395 63d793cfea1220e77f4a0da5f9b8fb50 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 63 2.0E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS38395 63d793cfea1220e77f4a0da5f9b8fb50 204 Gene3D G3DSA:1.10.357.10 60 188 5.0E-20 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS38395 63d793cfea1220e77f4a0da5f9b8fb50 204 SUPERFAMILY SSF46689 5 85 2.0E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS38395 63d793cfea1220e77f4a0da5f9b8fb50 204 PANTHER PTHR30328 8 194 9.9E-38 T 23-04-2016 DC74_RS14610 b220ed19159492bfae2f7297f0dc5f94 455 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 17 449 30.624 T 23-04-2016 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 DC74_RS14610 b220ed19159492bfae2f7297f0dc5f94 455 Gene3D G3DSA:1.10.3210.10 27 233 2.1E-62 T 23-04-2016 IPR006674 HD domain DC74_RS14610 b220ed19159492bfae2f7297f0dc5f94 455 SMART SM00471 79 247 3.9E-12 T 23-04-2016 IPR003607 HD/PDEase domain DC74_RS14610 b220ed19159492bfae2f7297f0dc5f94 455 SUPERFAMILY SSF109604 35 187 1.51E-54 T 23-04-2016 DC74_RS14610 b220ed19159492bfae2f7297f0dc5f94 455 SUPERFAMILY SSF109604 218 322 1.51E-54 T 23-04-2016 DC74_RS14610 b220ed19159492bfae2f7297f0dc5f94 455 SUPERFAMILY SSF109604 360 403 1.51E-54 T 23-04-2016 DC74_RS14610 b220ed19159492bfae2f7297f0dc5f94 455 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 41 449 1.8E-72 T 23-04-2016 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 DC74_RS14610 b220ed19159492bfae2f7297f0dc5f94 455 Pfam PF13286 Phosphohydrolase-associated domain 356 447 2.1E-19 T 23-04-2016 IPR026875 Phosphohydrolase-associated domain DC74_RS14610 b220ed19159492bfae2f7297f0dc5f94 455 PANTHER PTHR11373 36 187 1.5E-39 T 23-04-2016 DC74_RS14610 b220ed19159492bfae2f7297f0dc5f94 455 Gene3D G3DSA:1.10.3410.10 234 376 1.9E-17 T 23-04-2016 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain DC74_RS14610 b220ed19159492bfae2f7297f0dc5f94 455 Pfam PF01966 HD domain 83 205 3.8E-15 T 23-04-2016 IPR006674 HD domain DC74_RS29800 6e3d8dde5c1138f275f00c8c65c21fa4 485 SUPERFAMILY SSF53720 11 480 5.5E-134 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS29800 6e3d8dde5c1138f275f00c8c65c21fa4 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS29800 6e3d8dde5c1138f275f00c8c65c21fa4 485 PANTHER PTHR11699 21 485 8.2E-198 T 23-04-2016 DC74_RS29800 6e3d8dde5c1138f275f00c8c65c21fa4 485 PANTHER PTHR11699:SF167 21 485 8.2E-198 T 23-04-2016 DC74_RS29800 6e3d8dde5c1138f275f00c8c65c21fa4 485 Gene3D G3DSA:3.40.605.10 9 256 1.6E-73 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS29800 6e3d8dde5c1138f275f00c8c65c21fa4 485 Pfam PF00171 Aldehyde dehydrogenase family 15 473 2.1E-138 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS29800 6e3d8dde5c1138f275f00c8c65c21fa4 485 Gene3D G3DSA:3.40.309.10 257 448 1.0E-55 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS13295 7490b1398a2da4b98356b1d33c5e67b9 274 PANTHER PTHR10992 1 129 4.8E-20 T 23-04-2016 DC74_RS13295 7490b1398a2da4b98356b1d33c5e67b9 274 PANTHER PTHR10992 147 272 4.8E-20 T 23-04-2016 DC74_RS13295 7490b1398a2da4b98356b1d33c5e67b9 274 SUPERFAMILY SSF53474 2 272 5.77E-35 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS13295 7490b1398a2da4b98356b1d33c5e67b9 274 Pfam PF12697 Alpha/beta hydrolase family 19 269 4.4E-15 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS13295 7490b1398a2da4b98356b1d33c5e67b9 274 Gene3D G3DSA:3.40.50.1820 2 272 1.9E-32 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS00770 09b54f65cfbfab898128fe32de3f9354 261 SUPERFAMILY SSF53335 9 259 1.94E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS00770 09b54f65cfbfab898128fe32de3f9354 261 PANTHER PTHR10108 189 238 5.9E-21 T 23-04-2016 DC74_RS00770 09b54f65cfbfab898128fe32de3f9354 261 PANTHER PTHR10108 9 161 5.9E-21 T 23-04-2016 DC74_RS00770 09b54f65cfbfab898128fe32de3f9354 261 PANTHER PTHR10108:SF705 189 238 5.9E-21 T 23-04-2016 DC74_RS00770 09b54f65cfbfab898128fe32de3f9354 261 PANTHER PTHR10108:SF705 9 161 5.9E-21 T 23-04-2016 DC74_RS00770 09b54f65cfbfab898128fe32de3f9354 261 Pfam PF13649 Methyltransferase domain 54 147 2.5E-18 T 23-04-2016 DC74_RS00770 09b54f65cfbfab898128fe32de3f9354 261 Gene3D G3DSA:3.40.50.150 8 174 1.0E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS00770 09b54f65cfbfab898128fe32de3f9354 261 Gene3D G3DSA:3.40.50.150 213 239 1.0E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS02490 dee54ac82f9490f0db3478bddee88b67 270 Pfam PF10370 Domain of unknown function (DUF2437) 1 65 3.2E-8 T 23-04-2016 IPR018833 Domain of unknown function DUF2437 DC74_RS02490 dee54ac82f9490f0db3478bddee88b67 270 Gene3D G3DSA:3.90.850.10 62 263 1.7E-68 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS02490 dee54ac82f9490f0db3478bddee88b67 270 SUPERFAMILY SSF56529 68 259 3.79E-62 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS02490 dee54ac82f9490f0db3478bddee88b67 270 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 86 260 1.7E-53 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS02490 dee54ac82f9490f0db3478bddee88b67 270 PANTHER PTHR11820:SF6 54 259 3.8E-76 T 23-04-2016 DC74_RS02490 dee54ac82f9490f0db3478bddee88b67 270 PANTHER PTHR11820 54 259 3.8E-76 T 23-04-2016 DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 PANTHER PTHR23406 155 687 1.4E-54 T 23-04-2016 DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 382 683 4.5E-124 T 23-04-2016 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 PIRSF PIRSF006107 1 691 1.3E-178 T 23-04-2016 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 Pfam PF07085 DRTGG domain 209 319 1.6E-21 T 23-04-2016 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 SUPERFAMILY SSF75138 204 321 1.41E-18 T 23-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 Pfam PF01515 Phosphate acetyl/butaryl transferase 366 683 4.8E-127 T 23-04-2016 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 Gene3D G3DSA:3.40.50.300 3 205 1.9E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 Gene3D G3DSA:3.40.50.10750 501 659 1.0E-67 T 23-04-2016 DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 SUPERFAMILY SSF53659 365 686 5.76E-95 T 23-04-2016 DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 Pfam PF13500 AAA domain 3 205 1.3E-16 T 23-04-2016 DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 Gene3D G3DSA:3.40.1390.20 206 342 6.8E-25 T 23-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 SUPERFAMILY SSF52540 4 216 4.14E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27275 a6b03096c17b0916ac5b88f24eebbe97 697 PANTHER PTHR23406:SF3 155 687 1.4E-54 T 23-04-2016 DC74_RS34995 4388c195cdf25aa7a5b97e5416428641 297 Gene3D G3DSA:3.40.50.1820 8 273 2.1E-41 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34995 4388c195cdf25aa7a5b97e5416428641 297 Pfam PF00561 alpha/beta hydrolase fold 44 261 1.6E-20 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS34995 4388c195cdf25aa7a5b97e5416428641 297 PRINTS PR00412 Epoxide hydrolase signature 249 271 9.5E-8 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS34995 4388c195cdf25aa7a5b97e5416428641 297 PRINTS PR00412 Epoxide hydrolase signature 54 69 9.5E-8 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS34995 4388c195cdf25aa7a5b97e5416428641 297 PRINTS PR00412 Epoxide hydrolase signature 216 232 9.5E-8 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS34995 4388c195cdf25aa7a5b97e5416428641 297 PRINTS PR00412 Epoxide hydrolase signature 112 125 9.5E-8 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS34995 4388c195cdf25aa7a5b97e5416428641 297 SUPERFAMILY SSF53474 7 272 1.47E-41 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34995 4388c195cdf25aa7a5b97e5416428641 297 PANTHER PTHR10992 7 274 2.6E-29 T 23-04-2016 DC74_RS34995 4388c195cdf25aa7a5b97e5416428641 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 218 232 2.7E-8 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS34995 4388c195cdf25aa7a5b97e5416428641 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 2.7E-8 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS34995 4388c195cdf25aa7a5b97e5416428641 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 2.7E-8 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS34995 4388c195cdf25aa7a5b97e5416428641 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.7E-8 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS10200 af86a61cb96dbed798821a232b8f0f6b 252 Gene3D G3DSA:3.40.50.1980 132 241 2.7E-12 T 23-04-2016 DC74_RS10200 af86a61cb96dbed798821a232b8f0f6b 252 SUPERFAMILY SSF53807 8 241 2.83E-32 T 23-04-2016 DC74_RS10200 af86a61cb96dbed798821a232b8f0f6b 252 PANTHER PTHR30535:SF6 1 241 1.9E-97 T 23-04-2016 DC74_RS10200 af86a61cb96dbed798821a232b8f0f6b 252 Gene3D G3DSA:3.40.50.1980 8 105 4.2E-19 T 23-04-2016 DC74_RS10200 af86a61cb96dbed798821a232b8f0f6b 252 PANTHER PTHR30535 1 241 1.9E-97 T 23-04-2016 DC74_RS18460 6c656b59261e2777b556312fe9546184 303 Gene3D G3DSA:1.10.10.10 3 88 2.1E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18460 6c656b59261e2777b556312fe9546184 303 Pfam PF03466 LysR substrate binding domain 89 301 9.8E-40 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS18460 6c656b59261e2777b556312fe9546184 303 SUPERFAMILY SSF46785 3 112 5.26E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18460 6c656b59261e2777b556312fe9546184 303 SUPERFAMILY SSF53850 91 302 1.86E-34 T 23-04-2016 DC74_RS18460 6c656b59261e2777b556312fe9546184 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.3E-24 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS18460 6c656b59261e2777b556312fe9546184 303 PANTHER PTHR30346:SF2 2 301 8.3E-99 T 23-04-2016 DC74_RS18460 6c656b59261e2777b556312fe9546184 303 PANTHER PTHR30346 2 301 8.3E-99 T 23-04-2016 DC74_RS18460 6c656b59261e2777b556312fe9546184 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.4E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS18460 6c656b59261e2777b556312fe9546184 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.4E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS18460 6c656b59261e2777b556312fe9546184 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.4E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS18460 6c656b59261e2777b556312fe9546184 303 Gene3D G3DSA:3.40.190.10 91 186 1.7E-17 T 23-04-2016 DC74_RS18460 6c656b59261e2777b556312fe9546184 303 Gene3D G3DSA:3.40.190.10 187 273 2.3E-27 T 23-04-2016 DC74_RS15040 9f69b5e723ade2e58bd2027000375b30 244 PANTHER PTHR11935 1 238 2.7E-26 T 23-04-2016 DC74_RS15040 9f69b5e723ade2e58bd2027000375b30 244 Pfam PF00753 Metallo-beta-lactamase superfamily 29 219 6.4E-16 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS15040 9f69b5e723ade2e58bd2027000375b30 244 PANTHER PTHR11935:SF28 1 238 2.7E-26 T 23-04-2016 DC74_RS15040 9f69b5e723ade2e58bd2027000375b30 244 Gene3D G3DSA:3.60.15.10 7 238 2.8E-47 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS15040 9f69b5e723ade2e58bd2027000375b30 244 SMART SM00849 26 219 3.6E-17 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS15040 9f69b5e723ade2e58bd2027000375b30 244 SUPERFAMILY SSF56281 6 238 4.2E-38 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS34555 0fbaae6ea6fbf5e0022c36b3689c0799 174 Pfam PF07883 Cupin domain 84 152 5.6E-15 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS34555 0fbaae6ea6fbf5e0022c36b3689c0799 174 Gene3D G3DSA:2.60.120.10 54 152 3.5E-17 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS34555 0fbaae6ea6fbf5e0022c36b3689c0799 174 SUPERFAMILY SSF51182 53 157 3.79E-18 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS12650 cb5cfa9567585485690d4343260e64ac 305 SUPERFAMILY SSF51730 15 302 3.53E-92 T 23-04-2016 IPR029041 FAD-linked oxidoreductase-like DC74_RS12650 cb5cfa9567585485690d4343260e64ac 305 Pfam PF02219 Methylenetetrahydrofolate reductase 16 300 6.7E-106 T 23-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 DC74_RS12650 cb5cfa9567585485690d4343260e64ac 305 Gene3D G3DSA:3.20.20.220 12 303 3.9E-103 T 23-04-2016 IPR029041 FAD-linked oxidoreductase-like DC74_RS12650 cb5cfa9567585485690d4343260e64ac 305 PANTHER PTHR21091 158 301 3.7E-36 T 23-04-2016 DC74_RS12650 cb5cfa9567585485690d4343260e64ac 305 PANTHER PTHR21091:SF31 158 301 3.7E-36 T 23-04-2016 DC74_RS12650 cb5cfa9567585485690d4343260e64ac 305 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 27 299 1.0E-97 T 23-04-2016 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 DC74_RS09250 3d7a9f0b976861963feafa649c784aca 161 Pfam PF03061 Thioesterase superfamily 31 115 3.0E-13 T 23-04-2016 IPR006683 Thioesterase domain DC74_RS09250 3d7a9f0b976861963feafa649c784aca 161 PANTHER PTHR31793 17 160 2.9E-22 T 23-04-2016 DC74_RS09250 3d7a9f0b976861963feafa649c784aca 161 Gene3D G3DSA:3.10.129.10 17 149 1.6E-31 T 23-04-2016 IPR029069 HotDog domain DC74_RS09250 3d7a9f0b976861963feafa649c784aca 161 SUPERFAMILY SSF54637 17 149 2.87E-29 T 23-04-2016 IPR029069 HotDog domain DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 Gene3D G3DSA:3.30.70.260 351 422 1.7E-11 T 23-04-2016 DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 SUPERFAMILY SSF55021 350 422 5.6E-14 T 23-04-2016 DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 23-04-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 Pfam PF00742 Homoserine dehydrogenase 139 319 7.0E-67 T 23-04-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 SUPERFAMILY SSF51735 5 160 6.45E-32 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 PIRSF PIRSF000098 4 430 2.3E-156 T 23-04-2016 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 Pfam PF01842 ACT domain 354 415 2.9E-12 T 23-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 Gene3D G3DSA:3.40.50.720 2 150 7.9E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 PANTHER PTHR21499:SF2 1 325 6.3E-129 T 23-04-2016 DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 Gene3D G3DSA:3.30.360.10 151 303 6.9E-55 T 23-04-2016 DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 PANTHER PTHR21499 1 325 6.3E-129 T 23-04-2016 DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 13 131 1.0E-20 T 23-04-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 DC74_RS26850 ca06544f8fb3a08b3f7d67a9ca4aa476 430 SUPERFAMILY SSF55347 139 306 8.5E-53 T 23-04-2016 DC74_RS29525 c9b63eda918179a8fd01b266038f5709 453 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 306 440 4.0E-31 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS29525 c9b63eda918179a8fd01b266038f5709 453 Gene3D G3DSA:3.40.50.970 287 442 6.5E-46 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS29525 c9b63eda918179a8fd01b266038f5709 453 PANTHER PTHR18968:SF13 24 441 6.1E-81 T 23-04-2016 DC74_RS29525 c9b63eda918179a8fd01b266038f5709 453 Gene3D G3DSA:3.40.50.1220 100 286 4.2E-39 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS29525 c9b63eda918179a8fd01b266038f5709 453 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 79 7.9E-13 T 23-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DC74_RS29525 c9b63eda918179a8fd01b266038f5709 453 SUPERFAMILY SSF52518 8 82 6.43E-11 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS29525 c9b63eda918179a8fd01b266038f5709 453 SUPERFAMILY SSF52467 63 252 6.99E-37 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS29525 c9b63eda918179a8fd01b266038f5709 453 PANTHER PTHR18968 24 441 6.1E-81 T 23-04-2016 DC74_RS29525 c9b63eda918179a8fd01b266038f5709 453 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 332 351 - T 23-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 DC74_RS29525 c9b63eda918179a8fd01b266038f5709 453 SUPERFAMILY SSF52518 276 442 4.61E-47 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS29525 c9b63eda918179a8fd01b266038f5709 453 Gene3D G3DSA:3.40.50.970 1 82 7.4E-13 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS29525 c9b63eda918179a8fd01b266038f5709 453 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 105 235 6.5E-28 T 23-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DC74_RS29645 b7ec3ea586e7de572262a763af067b28 233 PANTHER PTHR30050 88 231 1.0E-28 T 23-04-2016 DC74_RS29645 b7ec3ea586e7de572262a763af067b28 233 Gene3D G3DSA:3.40.50.300 74 218 3.1E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS29645 b7ec3ea586e7de572262a763af067b28 233 Pfam PF01695 IstB-like ATP binding protein 92 208 5.7E-18 T 23-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 DC74_RS29645 b7ec3ea586e7de572262a763af067b28 233 SMART SM00382 90 214 0.001 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS29645 b7ec3ea586e7de572262a763af067b28 233 SUPERFAMILY SSF52540 86 225 1.72E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07030 3afb7acb96441f3061a7f7df3072fb48 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 66 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS07030 3afb7acb96441f3061a7f7df3072fb48 198 PANTHER PTHR30055 9 190 1.1E-22 T 23-04-2016 DC74_RS07030 3afb7acb96441f3061a7f7df3072fb48 198 Gene3D G3DSA:1.10.10.60 13 70 4.1E-23 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07030 3afb7acb96441f3061a7f7df3072fb48 198 Gene3D G3DSA:1.10.357.10 77 193 4.0E-25 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS07030 3afb7acb96441f3061a7f7df3072fb48 198 SUPERFAMILY SSF46689 14 80 6.16E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07030 3afb7acb96441f3061a7f7df3072fb48 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.4E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS07030 3afb7acb96441f3061a7f7df3072fb48 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.4E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS07030 3afb7acb96441f3061a7f7df3072fb48 198 SUPERFAMILY SSF48498 85 192 4.89E-15 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS07030 3afb7acb96441f3061a7f7df3072fb48 198 PANTHER PTHR30055:SF53 9 190 1.1E-22 T 23-04-2016 DC74_RS07030 3afb7acb96441f3061a7f7df3072fb48 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 1.2E-19 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS18415 b4404249372482c9f4439f5115d304ec 674 SMART SM00220 13 271 1.4E-51 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS18415 b4404249372482c9f4439f5115d304ec 674 Pfam PF00069 Protein kinase domain 14 259 1.9E-41 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS18415 b4404249372482c9f4439f5115d304ec 674 PANTHER PTHR24362 461 523 1.2E-79 T 23-04-2016 DC74_RS18415 b4404249372482c9f4439f5115d304ec 674 PANTHER PTHR24362 5 367 1.2E-79 T 23-04-2016 DC74_RS18415 b4404249372482c9f4439f5115d304ec 674 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS18415 b4404249372482c9f4439f5115d304ec 674 Gene3D G3DSA:1.10.510.10 83 268 3.6E-43 T 23-04-2016 DC74_RS18415 b4404249372482c9f4439f5115d304ec 674 Gene3D G3DSA:3.30.200.20 4 82 1.4E-20 T 23-04-2016 DC74_RS18415 b4404249372482c9f4439f5115d304ec 674 PANTHER PTHR24362:SF247 461 523 1.2E-79 T 23-04-2016 DC74_RS18415 b4404249372482c9f4439f5115d304ec 674 PANTHER PTHR24362:SF247 5 367 1.2E-79 T 23-04-2016 DC74_RS18415 b4404249372482c9f4439f5115d304ec 674 SUPERFAMILY SSF56112 5 296 7.82E-64 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS18415 b4404249372482c9f4439f5115d304ec 674 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 19 42 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS05605 abe20e27d36e2934c94344dbac93f6cc 102 SUPERFAMILY SSF54909 1 77 7.02E-9 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS05605 abe20e27d36e2934c94344dbac93f6cc 102 Gene3D G3DSA:3.30.70.900 7 68 5.5E-5 T 23-04-2016 DC74_RS06970 944e257caa10b8ba7916ae3b288eb812 482 SUPERFAMILY SSF53383 27 445 8.34E-134 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS06970 944e257caa10b8ba7916ae3b288eb812 482 PANTHER PTHR11999:SF99 34 450 2.4E-215 T 23-04-2016 DC74_RS06970 944e257caa10b8ba7916ae3b288eb812 482 Gene3D G3DSA:3.40.640.10 76 325 1.2E-27 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS06970 944e257caa10b8ba7916ae3b288eb812 482 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 27 445 1.5E-196 T 23-04-2016 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 DC74_RS06970 944e257caa10b8ba7916ae3b288eb812 482 PANTHER PTHR11999 34 450 2.4E-215 T 23-04-2016 DC74_RS06970 944e257caa10b8ba7916ae3b288eb812 482 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 41 380 3.2E-80 T 23-04-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 DC74_RS36815 dc5ddf1cf155567cce2600f1dd6cd7b7 159 Pfam PF14232 Domain of unknown function (DUF4334) 92 146 2.3E-23 T 23-04-2016 IPR025568 Domain of unknown function DUF4334 DC74_RS36815 dc5ddf1cf155567cce2600f1dd6cd7b7 159 Pfam PF14231 GXWXG protein 24 82 2.4E-20 T 23-04-2016 IPR025951 GXWXG domain DC74_RS36590 d58af0eb0a15f8c02c1f4b0fa0c8ece3 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS36590 d58af0eb0a15f8c02c1f4b0fa0c8ece3 514 Gene3D G3DSA:2.30.38.10 331 393 4.2E-8 T 23-04-2016 DC74_RS36590 d58af0eb0a15f8c02c1f4b0fa0c8ece3 514 Gene3D G3DSA:3.30.300.30 413 508 3.5E-29 T 23-04-2016 DC74_RS36590 d58af0eb0a15f8c02c1f4b0fa0c8ece3 514 SUPERFAMILY SSF56801 7 510 4.32E-109 T 23-04-2016 DC74_RS36590 d58af0eb0a15f8c02c1f4b0fa0c8ece3 514 PANTHER PTHR24095 6 500 4.9E-118 T 23-04-2016 DC74_RS36590 d58af0eb0a15f8c02c1f4b0fa0c8ece3 514 Pfam PF00501 AMP-binding enzyme 16 416 4.4E-64 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS36590 d58af0eb0a15f8c02c1f4b0fa0c8ece3 514 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 500 6.8E-10 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS36590 d58af0eb0a15f8c02c1f4b0fa0c8ece3 514 Gene3D G3DSA:3.40.50.980 8 162 1.3E-33 T 23-04-2016 DC74_RS36590 d58af0eb0a15f8c02c1f4b0fa0c8ece3 514 Gene3D G3DSA:3.40.50.980 163 330 1.8E-35 T 23-04-2016 DC74_RS05230 86708aa06d102e581709de6c3eb7f176 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 264 8.0E-14 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS05230 86708aa06d102e581709de6c3eb7f176 282 PANTHER PTHR30465 8 266 1.3E-34 T 23-04-2016 DC74_RS05230 86708aa06d102e581709de6c3eb7f176 282 SUPERFAMILY SSF161098 69 257 5.23E-13 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS01860 d170297f612ddb8ec431c162b64c37d9 320 PANTHER PTHR23091:SF232 146 316 2.2E-29 T 23-04-2016 DC74_RS01860 d170297f612ddb8ec431c162b64c37d9 320 PANTHER PTHR23091 146 316 2.2E-29 T 23-04-2016 DC74_RS01860 d170297f612ddb8ec431c162b64c37d9 320 SUPERFAMILY SSF55729 1 134 2.23E-21 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS01860 d170297f612ddb8ec431c162b64c37d9 320 SUPERFAMILY SSF55729 176 301 3.97E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS01860 d170297f612ddb8ec431c162b64c37d9 320 Gene3D G3DSA:3.40.630.30 3 163 1.5E-30 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS01860 d170297f612ddb8ec431c162b64c37d9 320 Gene3D G3DSA:3.40.630.30 176 318 8.6E-31 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS01860 d170297f612ddb8ec431c162b64c37d9 320 Pfam PF00583 Acetyltransferase (GNAT) family 219 298 1.9E-14 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS01860 d170297f612ddb8ec431c162b64c37d9 320 Pfam PF00583 Acetyltransferase (GNAT) family 64 133 1.9E-12 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS02550 450dd77d751f7f6eedb438a3706bec54 388 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 9 292 1.6E-77 T 23-04-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 DC74_RS02550 450dd77d751f7f6eedb438a3706bec54 388 PANTHER PTHR36510 1 387 3.5E-87 T 23-04-2016 DC74_RS02550 450dd77d751f7f6eedb438a3706bec54 388 SUPERFAMILY SSF55931 7 378 6.67E-80 T 23-04-2016 DC74_RS02550 450dd77d751f7f6eedb438a3706bec54 388 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 10 289 8.9E-44 T 23-04-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 DC74_RS02550 450dd77d751f7f6eedb438a3706bec54 388 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 388 69.198 T 23-04-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 DC74_RS12320 cb9742b6fed1905582700260bca8de1d 217 TIGRFAM TIGR02234 trp_oprn_chp: membrane protein, TIGR02234 family 26 216 7.7E-42 T 23-04-2016 IPR011746 Trp biosynthesis associated, conserved hypothetical membrane protein DC74_RS12320 cb9742b6fed1905582700260bca8de1d 217 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 32 216 3.4E-49 T 23-04-2016 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp DC74_RS10720 efddd483cf06579355e994d5e5d23ade 464 SUPERFAMILY SSF53720 4 462 1.05E-152 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS10720 efddd483cf06579355e994d5e5d23ade 464 Pfam PF00171 Aldehyde dehydrogenase family 13 461 6.3E-155 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS10720 efddd483cf06579355e994d5e5d23ade 464 Gene3D G3DSA:3.40.309.10 257 437 3.5E-56 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS10720 efddd483cf06579355e994d5e5d23ade 464 PANTHER PTHR11699 4 462 6.4E-227 T 23-04-2016 DC74_RS10720 efddd483cf06579355e994d5e5d23ade 464 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS10720 efddd483cf06579355e994d5e5d23ade 464 Gene3D G3DSA:3.40.605.10 6 256 6.6E-84 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS10720 efddd483cf06579355e994d5e5d23ade 464 PANTHER PTHR11699:SF212 4 462 6.4E-227 T 23-04-2016 DC74_RS19130 2f1875f893115642ad388a9b3af7cbbf 67 PIRSF PIRSF002599 1 67 2.7E-26 T 23-04-2016 IPR012156 Cold shock, CspA GO:0003676 DC74_RS19130 2f1875f893115642ad388a9b3af7cbbf 67 PRINTS PR00050 Cold shock protein signature 4 19 4.9E-18 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS19130 2f1875f893115642ad388a9b3af7cbbf 67 PRINTS PR00050 Cold shock protein signature 40 58 4.9E-18 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS19130 2f1875f893115642ad388a9b3af7cbbf 67 PRINTS PR00050 Cold shock protein signature 25 34 4.9E-18 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS19130 2f1875f893115642ad388a9b3af7cbbf 67 SMART SM00357 3 67 8.9E-31 T 23-04-2016 IPR011129 Cold shock protein GO:0003676 DC74_RS19130 2f1875f893115642ad388a9b3af7cbbf 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.2E-31 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 DC74_RS19130 2f1875f893115642ad388a9b3af7cbbf 67 Gene3D G3DSA:2.40.50.140 1 65 4.7E-32 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS19130 2f1875f893115642ad388a9b3af7cbbf 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 23-04-2016 IPR019844 Cold-shock conserved site DC74_RS19130 2f1875f893115642ad388a9b3af7cbbf 67 SUPERFAMILY SSF50249 1 65 8.36E-26 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS19130 2f1875f893115642ad388a9b3af7cbbf 67 PANTHER PTHR11544 1 67 7.1E-41 T 23-04-2016 DC74_RS33050 2324e2d87830fee28ff7a7fbb4485e3f 338 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 55 332 2.9E-23 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS33050 2324e2d87830fee28ff7a7fbb4485e3f 338 Gene3D G3DSA:3.60.10.10 79 254 1.5E-8 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS33050 2324e2d87830fee28ff7a7fbb4485e3f 338 PANTHER PTHR16320 51 337 6.0E-26 T 23-04-2016 DC74_RS33050 2324e2d87830fee28ff7a7fbb4485e3f 338 TIGRFAM TIGR03395 sphingomy: sphingomyelin phosphodiesterase 52 337 9.4E-98 T 23-04-2016 IPR017766 Sphingomyelinase C/phospholipase C GO:0005576|GO:0008081 DC74_RS33050 2324e2d87830fee28ff7a7fbb4485e3f 338 SUPERFAMILY SSF56219 49 336 1.21E-71 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS27175 8f9d68d6ce8e58dfa042732c35f2bd75 216 PANTHER PTHR38074:SF1 2 214 1.2E-36 T 23-04-2016 DC74_RS27175 8f9d68d6ce8e58dfa042732c35f2bd75 216 Pfam PF01987 Mitochondrial biogenesis AIM24 6 211 8.9E-36 T 23-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 DC74_RS27175 8f9d68d6ce8e58dfa042732c35f2bd75 216 Gene3D G3DSA:3.60.160.10 7 213 4.2E-44 T 23-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 DC74_RS27175 8f9d68d6ce8e58dfa042732c35f2bd75 216 PANTHER PTHR38074 2 214 1.2E-36 T 23-04-2016 DC74_RS27175 8f9d68d6ce8e58dfa042732c35f2bd75 216 SUPERFAMILY SSF51219 7 213 1.88E-45 T 23-04-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain DC74_RS12555 8c3847ca8bbaca7d9f7a47b579bc9a9d 354 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 347 23.918 T 23-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS12555 8c3847ca8bbaca7d9f7a47b579bc9a9d 354 ProSitePatterns PS01348 MraY family signature 2. 174 185 - T 23-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS12555 8c3847ca8bbaca7d9f7a47b579bc9a9d 354 PANTHER PTHR22926:SF5 223 350 7.0E-146 T 23-04-2016 DC74_RS12555 8c3847ca8bbaca7d9f7a47b579bc9a9d 354 PANTHER PTHR22926:SF5 1 205 7.0E-146 T 23-04-2016 DC74_RS12555 8c3847ca8bbaca7d9f7a47b579bc9a9d 354 PANTHER PTHR22926 223 350 7.0E-146 T 23-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS12555 8c3847ca8bbaca7d9f7a47b579bc9a9d 354 PANTHER PTHR22926 1 205 7.0E-146 T 23-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS12555 8c3847ca8bbaca7d9f7a47b579bc9a9d 354 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 23-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS12555 8c3847ca8bbaca7d9f7a47b579bc9a9d 354 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 343 2.4E-98 T 23-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS12555 8c3847ca8bbaca7d9f7a47b579bc9a9d 354 Pfam PF00953 Glycosyl transferase family 4 82 273 6.6E-38 T 23-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS12555 8c3847ca8bbaca7d9f7a47b579bc9a9d 354 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 55 6.6E-4 T 23-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS02100 abd85057f9946dc1407d2a7d70210987 220 SUPERFAMILY SSF48498 78 178 5.93E-16 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS02100 abd85057f9946dc1407d2a7d70210987 220 SUPERFAMILY SSF46689 6 72 4.64E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02100 abd85057f9946dc1407d2a7d70210987 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 4.4E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS02100 abd85057f9946dc1407d2a7d70210987 220 PANTHER PTHR30055:SF23 7 182 1.1E-23 T 23-04-2016 DC74_RS02100 abd85057f9946dc1407d2a7d70210987 220 Pfam PF13305 WHG domain 85 176 5.0E-15 T 23-04-2016 IPR025996 WHG domain DC74_RS02100 abd85057f9946dc1407d2a7d70210987 220 PANTHER PTHR30055 7 182 1.1E-23 T 23-04-2016 DC74_RS02100 abd85057f9946dc1407d2a7d70210987 220 Gene3D G3DSA:1.10.357.10 7 212 6.9E-38 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 PANTHER PTHR30294:SF25 531 734 1.1E-66 T 23-04-2016 DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 PANTHER PTHR30294:SF25 24 236 1.1E-66 T 23-04-2016 DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 SUPERFAMILY SSF101967 407 498 2.09E-5 T 23-04-2016 DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 PANTHER PTHR30294 531 734 1.1E-66 T 23-04-2016 DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 PANTHER PTHR30294 24 236 1.1E-66 T 23-04-2016 DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 Pfam PF12698 ABC-2 family transporter protein 25 158 5.4E-8 T 23-04-2016 DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 Pfam PF12698 ABC-2 family transporter protein 524 714 7.9E-19 T 23-04-2016 DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 3.5E-58 T 23-04-2016 IPR017500 Phage infection protein, YhgE, N-terminal DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 447 474 2.0E-8 T 23-04-2016 IPR023908 xxxLxxG heptad repeat DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 476 496 2.6E-4 T 23-04-2016 IPR023908 xxxLxxG heptad repeat DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 189 216 7.2E-6 T 23-04-2016 IPR023908 xxxLxxG heptad repeat DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 204 230 1.5E-6 T 23-04-2016 IPR023908 xxxLxxG heptad repeat DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 426 453 2.1E-6 T 23-04-2016 IPR023908 xxxLxxG heptad repeat DC74_RS15825 6c1862256ca55a5caf91d66b23e04191 734 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 516 721 1.1E-69 T 23-04-2016 IPR017501 Phage infection protein, YhgE, C-terminal DC74_RS09225 665f877b4a31c67e6b7e33fb549096f6 211 PIRSF PIRSF000498 1 209 1.3E-69 T 23-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS09225 665f877b4a31c67e6b7e33fb549096f6 211 SUPERFAMILY SSF63380 92 194 7.31E-33 T 23-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 DC74_RS09225 665f877b4a31c67e6b7e33fb549096f6 211 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 196 4.6E-61 T 23-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS09225 665f877b4a31c67e6b7e33fb549096f6 211 Gene3D G3DSA:2.40.30.20 104 195 1.8E-31 T 23-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS09225 665f877b4a31c67e6b7e33fb549096f6 211 Gene3D G3DSA:2.40.30.20 5 103 1.9E-33 T 23-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 DC74_RS09225 665f877b4a31c67e6b7e33fb549096f6 211 SUPERFAMILY SSF63380 2 87 9.35E-25 T 23-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 DC74_RS09225 665f877b4a31c67e6b7e33fb549096f6 211 PANTHER PTHR21098 2 204 1.5E-100 T 23-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS09225 665f877b4a31c67e6b7e33fb549096f6 211 Pfam PF00677 Lumazine binding domain 3 85 7.8E-23 T 23-04-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS09225 665f877b4a31c67e6b7e33fb549096f6 211 Pfam PF00677 Lumazine binding domain 99 183 3.0E-23 T 23-04-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 DC74_RS15780 a6a04759ef42d28da59472e51929e0a4 394 Gene3D G3DSA:3.20.20.70 71 336 1.8E-5 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS15780 a6a04759ef42d28da59472e51929e0a4 394 SUPERFAMILY SSF51569 38 337 8.69E-10 T 23-04-2016 DC74_RS15780 a6a04759ef42d28da59472e51929e0a4 394 Pfam PF06187 Protein of unknown function (DUF993) 12 388 4.7E-163 T 23-04-2016 IPR009334 Protein of unknown function DUF993 DC74_RS11715 52155f82b16c8adc7da1082a10faa558 418 PANTHER PTHR11601 11 417 1.4E-193 T 23-04-2016 DC74_RS11715 52155f82b16c8adc7da1082a10faa558 418 PANTHER PTHR11601:SF17 11 417 1.4E-193 T 23-04-2016 DC74_RS11715 52155f82b16c8adc7da1082a10faa558 418 Pfam PF00266 Aminotransferase class-V 31 406 7.5E-151 T 23-04-2016 IPR000192 Aminotransferase class V domain DC74_RS11715 52155f82b16c8adc7da1082a10faa558 418 Gene3D G3DSA:3.90.1150.10 294 412 3.2E-28 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS11715 52155f82b16c8adc7da1082a10faa558 418 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 12 418 1.5E-185 T 23-04-2016 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 DC74_RS11715 52155f82b16c8adc7da1082a10faa558 418 SUPERFAMILY SSF53383 9 413 8.99E-123 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS11715 52155f82b16c8adc7da1082a10faa558 418 Gene3D G3DSA:3.40.640.10 42 293 8.9E-85 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS01995 378123a727fa7aee3a773452226a8a75 246 PANTHER PTHR31223 35 216 6.0E-38 T 23-04-2016 DC74_RS01995 378123a727fa7aee3a773452226a8a75 246 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 43 216 3.6E-29 T 23-04-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG DC74_RS01995 378123a727fa7aee3a773452226a8a75 246 SUPERFAMILY SSF102405 41 215 9.01E-34 T 23-04-2016 DC74_RS01995 378123a727fa7aee3a773452226a8a75 246 PANTHER PTHR31223:SF1 35 216 6.0E-38 T 23-04-2016 DC74_RS01995 378123a727fa7aee3a773452226a8a75 246 Gene3D G3DSA:3.40.50.450 33 220 1.3E-37 T 23-04-2016 DC74_RS01995 378123a727fa7aee3a773452226a8a75 246 Pfam PF03641 Possible lysine decarboxylase 84 215 5.1E-18 T 23-04-2016 IPR031100 LOG family DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 Gene3D G3DSA:3.20.20.60 252 551 8.8E-88 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 PANTHER PTHR22931 67 534 6.2E-146 T 23-04-2016 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 Gene3D G3DSA:1.10.274.10 28 129 9.9E-21 T 23-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 181 192 - T 23-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 PANTHER PTHR22931:SF28 67 534 6.2E-146 T 23-04-2016 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 253 524 9.3E-79 T 23-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 Pfam PF00391 PEP-utilising enzyme, mobile domain 150 221 7.4E-22 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 PIRSF PIRSF000732 1 556 3.9E-171 T 23-04-2016 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 SUPERFAMILY SSF47831 30 140 1.57E-20 T 23-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 448 463 5.2E-18 T 23-04-2016 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 285 304 5.2E-18 T 23-04-2016 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 431 446 5.2E-18 T 23-04-2016 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 484 496 5.2E-18 T 23-04-2016 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 123 2.4E-21 T 23-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 431 449 - T 23-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 Gene3D G3DSA:3.50.30.10 130 244 9.0E-35 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 542 7.4E-127 T 23-04-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 SUPERFAMILY SSF52009 123 240 4.19E-31 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS08160 5c55b84030393b5ddb5963068561bb20 556 SUPERFAMILY SSF51621 250 533 1.91E-84 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS19975 88b8d51ffc1dfe06116babd27db7096a 165 Pfam PF00156 Phosphoribosyl transferase domain 15 152 7.9E-24 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 DC74_RS19975 88b8d51ffc1dfe06116babd27db7096a 165 PANTHER PTHR22573:SF51 17 149 1.7E-16 T 23-04-2016 DC74_RS19975 88b8d51ffc1dfe06116babd27db7096a 165 PANTHER PTHR22573 17 149 1.7E-16 T 23-04-2016 DC74_RS19975 88b8d51ffc1dfe06116babd27db7096a 165 Gene3D G3DSA:3.40.50.2020 9 153 2.8E-32 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS19975 88b8d51ffc1dfe06116babd27db7096a 165 SUPERFAMILY SSF53271 9 151 3.54E-25 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like DC74_RS02120 dd0261f50b633378afa374a2ef73816c 326 SUPERFAMILY SSF46689 222 272 1.64E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02120 dd0261f50b633378afa374a2ef73816c 326 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 275 320 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS02120 dd0261f50b633378afa374a2ef73816c 326 SMART SM00342 238 324 5.0E-27 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS02120 dd0261f50b633378afa374a2ef73816c 326 Gene3D G3DSA:1.10.10.60 220 276 4.3E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02120 dd0261f50b633378afa374a2ef73816c 326 Pfam PF12833 Helix-turn-helix domain 244 325 1.6E-24 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS02120 dd0261f50b633378afa374a2ef73816c 326 PANTHER PTHR11019 40 325 6.1E-36 T 23-04-2016 DC74_RS02120 dd0261f50b633378afa374a2ef73816c 326 SUPERFAMILY SSF46689 275 325 1.22E-5 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02120 dd0261f50b633378afa374a2ef73816c 326 Gene3D G3DSA:1.10.10.60 277 322 2.7E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS02120 dd0261f50b633378afa374a2ef73816c 326 Pfam PF14525 AraC-binding-like domain 22 201 1.7E-42 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS02120 dd0261f50b633378afa374a2ef73816c 326 PANTHER PTHR11019:SF54 40 325 6.1E-36 T 23-04-2016 DC74_RS12950 0a43d10710eb9926cc2b8c3acab50f0d 397 PANTHER PTHR30573:SF0 5 396 2.4E-186 T 23-04-2016 DC74_RS12950 0a43d10710eb9926cc2b8c3acab50f0d 397 Hamap MF_00569 Quinolinate synthase A [nadA]. 41 396 55.503 T 23-04-2016 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 DC74_RS12950 0a43d10710eb9926cc2b8c3acab50f0d 397 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 47 396 1.0E-94 T 23-04-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 DC74_RS12950 0a43d10710eb9926cc2b8c3acab50f0d 397 Pfam PF02445 Quinolinate synthetase A protein 52 395 2.3E-104 T 23-04-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 DC74_RS12950 0a43d10710eb9926cc2b8c3acab50f0d 397 PANTHER PTHR30573 5 396 2.4E-186 T 23-04-2016 DC74_RS12950 0a43d10710eb9926cc2b8c3acab50f0d 397 SUPERFAMILY SSF142754 50 396 7.85E-92 T 23-04-2016 DC74_RS21435 79dcb50c42c3ebdf9a4f0c39940f3b50 219 PANTHER PTHR35569 9 219 4.4E-83 T 23-04-2016 DC74_RS21435 79dcb50c42c3ebdf9a4f0c39940f3b50 219 Gene3D G3DSA:1.10.3210.10 39 146 5.4E-9 T 23-04-2016 IPR006674 HD domain DC74_RS21435 79dcb50c42c3ebdf9a4f0c39940f3b50 219 Pfam PF01966 HD domain 39 124 1.6E-7 T 23-04-2016 IPR006674 HD domain DC74_RS21435 79dcb50c42c3ebdf9a4f0c39940f3b50 219 SUPERFAMILY SSF109604 24 145 1.77E-15 T 23-04-2016 DC74_RS21435 79dcb50c42c3ebdf9a4f0c39940f3b50 219 PANTHER PTHR35569:SF1 9 219 4.4E-83 T 23-04-2016 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 Pfam PF01494 FAD binding domain 2 334 4.4E-78 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 PANTHER PTHR13789 1 345 4.3E-84 T 23-04-2016 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 PANTHER PTHR13789:SF90 1 345 4.3E-84 T 23-04-2016 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 SUPERFAMILY SSF51905 2 163 7.5E-58 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 SUPERFAMILY SSF51905 256 345 7.5E-58 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 Gene3D G3DSA:3.50.50.60 257 337 6.8E-56 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 Gene3D G3DSA:3.50.50.60 1 168 6.8E-56 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 6.8E-45 T 23-04-2016 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 142 157 6.8E-45 T 23-04-2016 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 300 6.8E-45 T 23-04-2016 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 269 284 6.8E-45 T 23-04-2016 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 336 6.8E-45 T 23-04-2016 DC74_RS07755 9e8aebb071cdd501f2bd1fbefcbeff79 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 320 6.8E-45 T 23-04-2016 DC74_RS34540 e002e6cf23415594c1e10046c089f834 219 SUPERFAMILY SSF46689 4 85 2.1E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS34540 e002e6cf23415594c1e10046c089f834 219 Gene3D G3DSA:1.10.357.10 6 194 1.3E-38 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS34540 e002e6cf23415594c1e10046c089f834 219 SUPERFAMILY SSF48498 80 196 1.19E-25 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS34540 e002e6cf23415594c1e10046c089f834 219 PANTHER PTHR30328 4 197 2.0E-63 T 23-04-2016 DC74_RS34540 e002e6cf23415594c1e10046c089f834 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.2E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34540 e002e6cf23415594c1e10046c089f834 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.2E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34540 e002e6cf23415594c1e10046c089f834 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.9E-14 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34540 e002e6cf23415594c1e10046c089f834 219 PANTHER PTHR30328:SF29 4 197 2.0E-63 T 23-04-2016 DC74_RS27350 7583613e13f522fd5184afeba67bf858 617 SUPERFAMILY SSF90123 27 341 4.84E-71 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS27350 7583613e13f522fd5184afeba67bf858 617 Pfam PF00005 ABC transporter 380 532 2.3E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS27350 7583613e13f522fd5184afeba67bf858 617 SUPERFAMILY SSF52540 356 600 3.22E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27350 7583613e13f522fd5184afeba67bf858 617 SMART SM00382 389 586 1.2E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS27350 7583613e13f522fd5184afeba67bf858 617 Gene3D G3DSA:3.40.50.300 360 598 1.6E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27350 7583613e13f522fd5184afeba67bf858 617 ProSitePatterns PS00211 ABC transporters family signature. 505 519 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS27350 7583613e13f522fd5184afeba67bf858 617 Pfam PF00664 ABC transporter transmembrane region 40 310 2.3E-42 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS27350 7583613e13f522fd5184afeba67bf858 617 PANTHER PTHR24221 9 601 1.2E-170 T 23-04-2016 DC74_RS27350 7583613e13f522fd5184afeba67bf858 617 Gene3D G3DSA:1.20.1560.10 27 338 4.1E-68 T 23-04-2016 DC74_RS09090 afab87b4ef184ef70f2b389e7f9a16f4 449 Pfam PF00155 Aminotransferase class I and II 96 420 6.0E-15 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS09090 afab87b4ef184ef70f2b389e7f9a16f4 449 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 74 6.3E-12 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS09090 afab87b4ef184ef70f2b389e7f9a16f4 449 PANTHER PTHR11751 91 421 1.4E-35 T 23-04-2016 DC74_RS09090 afab87b4ef184ef70f2b389e7f9a16f4 449 SUPERFAMILY SSF53383 72 437 8.72E-57 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS09090 afab87b4ef184ef70f2b389e7f9a16f4 449 SMART SM00345 15 74 8.0E-10 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS09090 afab87b4ef184ef70f2b389e7f9a16f4 449 Gene3D G3DSA:1.10.10.10 14 82 1.9E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09090 afab87b4ef184ef70f2b389e7f9a16f4 449 Gene3D G3DSA:3.40.640.10 123 340 1.7E-38 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS09090 afab87b4ef184ef70f2b389e7f9a16f4 449 SUPERFAMILY SSF46785 11 83 1.12E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02805 c908971e6ec228be9e7b3014ba6a87aa 172 Gene3D G3DSA:3.40.50.1240 1 166 3.0E-51 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS02805 c908971e6ec228be9e7b3014ba6a87aa 172 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 2 68 1.4E-9 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS02805 c908971e6ec228be9e7b3014ba6a87aa 172 SUPERFAMILY SSF53254 2 149 3.47E-21 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS02805 c908971e6ec228be9e7b3014ba6a87aa 172 PANTHER PTHR20935 1 69 2.0E-15 T 23-04-2016 DC74_RS05950 dc4ce632087810c90f00c0c971a72f93 291 PANTHER PTHR10108:SF705 15 201 2.6E-25 T 23-04-2016 DC74_RS05950 dc4ce632087810c90f00c0c971a72f93 291 Gene3D G3DSA:3.40.50.150 30 213 8.7E-30 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS05950 dc4ce632087810c90f00c0c971a72f93 291 Pfam PF08241 Methyltransferase domain 45 144 1.8E-17 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS05950 dc4ce632087810c90f00c0c971a72f93 291 SUPERFAMILY SSF53335 12 257 1.43E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS05950 dc4ce632087810c90f00c0c971a72f93 291 PANTHER PTHR10108 15 201 2.6E-25 T 23-04-2016 DC74_RS02495 dca899a100aa8e12c04c8db899eaa189 133 PANTHER PTHR39199 1 128 1.8E-48 T 23-04-2016 DC74_RS02495 dca899a100aa8e12c04c8db899eaa189 133 SUPERFAMILY SSF55021 70 127 2.98E-18 T 23-04-2016 DC74_RS02495 dca899a100aa8e12c04c8db899eaa189 133 Pfam PF10000 ACT domain 2 68 4.2E-24 T 23-04-2016 IPR018717 Domain of unknown function DUF2241 DC74_RS02495 dca899a100aa8e12c04c8db899eaa189 133 SUPERFAMILY SSF55021 3 64 1.1E-13 T 23-04-2016 DC74_RS02495 dca899a100aa8e12c04c8db899eaa189 133 PANTHER PTHR39199:SF1 1 128 1.8E-48 T 23-04-2016 DC74_RS02495 dca899a100aa8e12c04c8db899eaa189 133 Gene3D G3DSA:3.30.2130.10 2 128 1.3E-50 T 23-04-2016 DC74_RS31435 a23af0d75c8e253c703aa00f7580e25e 376 TIGRFAM TIGR02961 allantoicase: allantoicase 39 357 1.2E-121 T 23-04-2016 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 DC74_RS31435 a23af0d75c8e253c703aa00f7580e25e 376 Pfam PF03561 Allantoicase repeat 47 206 1.2E-44 T 23-04-2016 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 DC74_RS31435 a23af0d75c8e253c703aa00f7580e25e 376 Pfam PF03561 Allantoicase repeat 229 357 4.4E-34 T 23-04-2016 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 DC74_RS31435 a23af0d75c8e253c703aa00f7580e25e 376 PIRSF PIRSF016516 30 361 6.1E-90 T 23-04-2016 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 DC74_RS31435 a23af0d75c8e253c703aa00f7580e25e 376 SUPERFAMILY SSF49785 33 210 2.47E-52 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS31435 a23af0d75c8e253c703aa00f7580e25e 376 SUPERFAMILY SSF49785 215 360 7.65E-41 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS31435 a23af0d75c8e253c703aa00f7580e25e 376 Gene3D G3DSA:2.60.120.260 34 210 1.4E-56 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS31435 a23af0d75c8e253c703aa00f7580e25e 376 Gene3D G3DSA:2.60.120.260 218 360 5.1E-40 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS31435 a23af0d75c8e253c703aa00f7580e25e 376 PANTHER PTHR12045 9 370 1.2E-116 T 23-04-2016 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 DC74_RS31435 a23af0d75c8e253c703aa00f7580e25e 376 Hamap MF_00813 Probable allantoicase [alc]. 23 360 49.364 T 23-04-2016 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697|UniPathway: UPA00395 DC74_RS33170 f6a7c86e827450acf48027ae39f61040 203 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 30 185 2.5E-36 T 23-04-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00059 DC74_RS33170 f6a7c86e827450acf48027ae39f61040 203 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 26 197 31.897 T 23-04-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00059 DC74_RS33170 f6a7c86e827450acf48027ae39f61040 203 Gene3D G3DSA:3.90.79.10 28 190 2.7E-49 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS33170 f6a7c86e827450acf48027ae39f61040 203 PANTHER PTHR10885 27 187 6.3E-54 T 23-04-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00059 DC74_RS33170 f6a7c86e827450acf48027ae39f61040 203 Pfam PF00293 NUDIX domain 53 181 9.3E-27 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS33170 f6a7c86e827450acf48027ae39f61040 203 PIRSF PIRSF018427 14 200 6.0E-52 T 23-04-2016 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00059 DC74_RS33170 f6a7c86e827450acf48027ae39f61040 203 SUPERFAMILY SSF55811 28 188 5.55E-46 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 PANTHER PTHR24291 254 456 7.9E-79 T 23-04-2016 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 Gene3D G3DSA:1.10.630.10 34 453 4.2E-91 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 Pfam PF00067 Cytochrome P450 34 439 1.9E-69 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 PRINTS PR00463 E-class P450 group I signature 44 63 2.3E-26 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 PRINTS PR00463 E-class P450 group I signature 401 424 2.3E-26 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 PRINTS PR00463 E-class P450 group I signature 391 401 2.3E-26 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 PRINTS PR00463 E-class P450 group I signature 253 270 2.3E-26 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 PRINTS PR00463 E-class P450 group I signature 273 299 2.3E-26 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 PRINTS PR00463 E-class P450 group I signature 356 380 2.3E-26 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 SUPERFAMILY SSF48264 17 453 1.28E-89 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 PRINTS PR00385 P450 superfamily signature 317 328 1.9E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 PRINTS PR00385 P450 superfamily signature 401 412 1.9E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 PRINTS PR00385 P450 superfamily signature 392 401 1.9E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06485 e770effcd0219bd8d825248a7da1f9cd 456 PRINTS PR00385 P450 superfamily signature 264 281 1.9E-8 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS33925 81fb0809673a78a7409988135199b866 976 Pfam PF12419 SNF2 Helicase protein 314 450 1.6E-40 T 23-04-2016 IPR022138 Helicase SWF/SNF-related DC74_RS33925 81fb0809673a78a7409988135199b866 976 Pfam PF00271 Helicase conserved C-terminal domain 807 915 9.8E-17 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS33925 81fb0809673a78a7409988135199b866 976 Pfam PF00176 SNF2 family N-terminal domain 517 781 2.2E-47 T 23-04-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 DC74_RS33925 81fb0809673a78a7409988135199b866 976 SUPERFAMILY SSF52540 719 971 7.83E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33925 81fb0809673a78a7409988135199b866 976 Gene3D G3DSA:3.40.50.300 800 950 8.0E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33925 81fb0809673a78a7409988135199b866 976 PANTHER PTHR10799 491 968 3.9E-152 T 23-04-2016 DC74_RS33925 81fb0809673a78a7409988135199b866 976 SMART SM00487 494 679 3.1E-29 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS33925 81fb0809673a78a7409988135199b866 976 Gene3D G3DSA:3.40.50.300 496 661 1.0E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33925 81fb0809673a78a7409988135199b866 976 SUPERFAMILY SSF52540 485 712 2.85E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33925 81fb0809673a78a7409988135199b866 976 SMART SM00490 833 915 3.0E-24 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS23320 b9efd6029dcfceb0e428dba6c22fa14f 175 Pfam PF02542 YgbB family 19 171 2.7E-44 T 23-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS23320 b9efd6029dcfceb0e428dba6c22fa14f 175 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 55 70 - T 23-04-2016 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS23320 b9efd6029dcfceb0e428dba6c22fa14f 175 PANTHER PTHR32125 10 173 1.2E-30 T 23-04-2016 DC74_RS23320 b9efd6029dcfceb0e428dba6c22fa14f 175 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 19 172 1.9E-42 T 23-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS23320 b9efd6029dcfceb0e428dba6c22fa14f 175 SUPERFAMILY SSF69765 18 173 3.66E-47 T 23-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS23320 b9efd6029dcfceb0e428dba6c22fa14f 175 Gene3D G3DSA:3.30.1330.50 18 173 5.0E-52 T 23-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS23320 b9efd6029dcfceb0e428dba6c22fa14f 175 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 17 173 30.39 T 23-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS25025 387596e9bb06fe6a3bf3a39921c619f0 313 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 52 275 3.1E-53 T 23-04-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 DC74_RS25025 387596e9bb06fe6a3bf3a39921c619f0 313 PANTHER PTHR10889:SF3 50 305 1.7E-127 T 23-04-2016 DC74_RS25025 387596e9bb06fe6a3bf3a39921c619f0 313 PIRSF PIRSF001357 43 303 1.3E-83 T 23-04-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 DC74_RS25025 387596e9bb06fe6a3bf3a39921c619f0 313 Gene3D G3DSA:3.20.20.70 43 305 1.1E-93 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS25025 387596e9bb06fe6a3bf3a39921c619f0 313 Pfam PF01791 DeoC/LacD family aldolase 45 291 1.0E-25 T 23-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 DC74_RS25025 387596e9bb06fe6a3bf3a39921c619f0 313 SUPERFAMILY SSF51569 50 293 2.62E-74 T 23-04-2016 DC74_RS25025 387596e9bb06fe6a3bf3a39921c619f0 313 SMART SM01133 49 294 8.4E-79 T 23-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 DC74_RS25025 387596e9bb06fe6a3bf3a39921c619f0 313 PANTHER PTHR10889 50 305 1.7E-127 T 23-04-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 DC74_RS22600 3a0da6398eacbd198a0c9d9d8ad1f99a 110 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 109 9.0E-32 T 23-04-2016 IPR024412 Lsr2 DC74_RS22600 3a0da6398eacbd198a0c9d9d8ad1f99a 110 Pfam PF11774 Lsr2 2 108 5.5E-41 T 23-04-2016 IPR024412 Lsr2 DC74_RS00595 7fef04e299d14239e69d9024fd3e756f 139 SUPERFAMILY SSF46785 16 126 3.91E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00595 7fef04e299d14239e69d9024fd3e756f 139 PANTHER PTHR33204 14 138 2.6E-48 T 23-04-2016 DC74_RS00595 7fef04e299d14239e69d9024fd3e756f 139 Gene3D G3DSA:1.10.10.10 14 130 3.6E-39 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00595 7fef04e299d14239e69d9024fd3e756f 139 Pfam PF01638 HxlR-like helix-turn-helix 31 121 7.6E-24 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS00595 7fef04e299d14239e69d9024fd3e756f 139 PANTHER PTHR33204:SF6 14 138 2.6E-48 T 23-04-2016 DC74_RS08050 f278a5f7e6b69c0e06ec3014f5928340 254 Pfam PF02517 CAAX protease self-immunity 146 235 1.4E-14 T 23-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 DC74_RS08615 413c241d51f159ed6135dd251ac8f704 132 Pfam PF01740 STAS domain 11 109 6.7E-10 T 23-04-2016 IPR002645 STAS domain DC74_RS08615 413c241d51f159ed6135dd251ac8f704 132 Gene3D G3DSA:3.30.750.24 10 114 3.1E-21 T 23-04-2016 IPR002645 STAS domain DC74_RS08615 413c241d51f159ed6135dd251ac8f704 132 PANTHER PTHR33495:SF2 11 118 6.5E-18 T 23-04-2016 DC74_RS08615 413c241d51f159ed6135dd251ac8f704 132 PANTHER PTHR33495 11 118 6.5E-18 T 23-04-2016 DC74_RS08615 413c241d51f159ed6135dd251ac8f704 132 SUPERFAMILY SSF52091 10 112 1.63E-18 T 23-04-2016 IPR002645 STAS domain DC74_RS29415 0507b6734750ebe57b6927fb76bd3f28 361 Gene3D G3DSA:3.90.226.10 6 199 1.1E-56 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS29415 0507b6734750ebe57b6927fb76bd3f28 361 SUPERFAMILY SSF52096 249 319 1.84E-65 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS29415 0507b6734750ebe57b6927fb76bd3f28 361 SUPERFAMILY SSF52096 5 197 1.84E-65 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS29415 0507b6734750ebe57b6927fb76bd3f28 361 PANTHER PTHR11941:SF53 245 319 4.0E-108 T 23-04-2016 DC74_RS29415 0507b6734750ebe57b6927fb76bd3f28 361 PANTHER PTHR11941:SF53 2 189 4.0E-108 T 23-04-2016 DC74_RS29415 0507b6734750ebe57b6927fb76bd3f28 361 Pfam PF16113 Enoyl-CoA hydratase/isomerase 17 336 2.3E-123 T 23-04-2016 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 DC74_RS29415 0507b6734750ebe57b6927fb76bd3f28 361 Gene3D G3DSA:1.10.12.10 261 319 4.9E-6 T 23-04-2016 IPR014748 Crontonase, C-terminal DC74_RS29415 0507b6734750ebe57b6927fb76bd3f28 361 PANTHER PTHR11941 2 189 4.0E-108 T 23-04-2016 DC74_RS29415 0507b6734750ebe57b6927fb76bd3f28 361 PANTHER PTHR11941 245 319 4.0E-108 T 23-04-2016 DC74_RS17265 4a51ec8b7a0496b84814d4b1d45a4a02 462 PIRSF PIRSF002744 2 460 2.7E-108 T 23-04-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 DC74_RS17265 4a51ec8b7a0496b84814d4b1d45a4a02 462 PANTHER PTHR31806 5 460 8.2E-113 T 23-04-2016 DC74_RS17265 4a51ec8b7a0496b84814d4b1d45a4a02 462 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 13 434 2.5E-55 T 23-04-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 DC74_RS34410 bebef581d5e04bf9def3e6253082115c 331 Pfam PF16864 Dimerisation domain 7 87 3.8E-10 T 23-04-2016 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain DC74_RS34410 bebef581d5e04bf9def3e6253082115c 331 SUPERFAMILY SSF53335 103 326 1.39E-45 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS34410 bebef581d5e04bf9def3e6253082115c 331 Gene3D G3DSA:1.10.10.10 3 80 3.5E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34410 bebef581d5e04bf9def3e6253082115c 331 PANTHER PTHR11746:SF63 1 331 2.8E-50 T 23-04-2016 DC74_RS34410 bebef581d5e04bf9def3e6253082115c 331 Gene3D G3DSA:3.40.50.150 100 327 1.8E-49 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS34410 bebef581d5e04bf9def3e6253082115c 331 Pfam PF00891 O-methyltransferase 106 314 1.0E-30 T 23-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 DC74_RS34410 bebef581d5e04bf9def3e6253082115c 331 SUPERFAMILY SSF46785 7 79 2.99E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34410 bebef581d5e04bf9def3e6253082115c 331 PANTHER PTHR11746 1 331 2.8E-50 T 23-04-2016 DC74_RS38970 fffe6546b8e866e56d9765c9884ca8cb 307 PANTHER PTHR10584:SF186 15 295 1.0E-74 T 23-04-2016 DC74_RS38970 fffe6546b8e866e56d9765c9884ca8cb 307 SUPERFAMILY SSF53613 8 295 2.34E-70 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS38970 fffe6546b8e866e56d9765c9884ca8cb 307 Gene3D G3DSA:3.40.1190.20 7 298 1.9E-75 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS38970 fffe6546b8e866e56d9765c9884ca8cb 307 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 23-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 DC74_RS38970 fffe6546b8e866e56d9765c9884ca8cb 307 PANTHER PTHR10584 15 295 1.0E-74 T 23-04-2016 DC74_RS38970 fffe6546b8e866e56d9765c9884ca8cb 307 Pfam PF00294 pfkB family carbohydrate kinase 9 291 9.1E-51 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 343 359 1.89E-41 T 23-04-2016 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 1.89E-41 T 23-04-2016 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.89E-41 T 23-04-2016 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 343 1.89E-41 T 23-04-2016 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 1.89E-41 T 23-04-2016 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 171 186 1.89E-41 T 23-04-2016 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 SUPERFAMILY SSF51905 2 192 3.57E-53 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 SUPERFAMILY SSF51905 279 368 3.57E-53 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 Gene3D G3DSA:3.50.50.60 2 72 2.0E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 Gene3D G3DSA:3.50.50.60 119 197 2.0E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 Gene3D G3DSA:3.50.50.60 280 362 2.0E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 PANTHER PTHR13789:SF90 2 366 8.6E-68 T 23-04-2016 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 PANTHER PTHR13789 2 366 8.6E-68 T 23-04-2016 DC74_RS39520 a2e3df9fdab8faca6841a596cba3aef8 507 Pfam PF01494 FAD binding domain 3 358 1.1E-62 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 SMART SM00421 152 209 1.8E-21 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 4.1E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 4.1E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 4.1E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 Gene3D G3DSA:3.40.50.2300 3 125 5.0E-33 T 23-04-2016 DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 PANTHER PTHR26402:SF564 3 216 7.0E-93 T 23-04-2016 DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 Pfam PF00072 Response regulator receiver domain 6 117 6.6E-24 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 SMART SM00448 3 117 1.0E-28 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 2.3E-17 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 PANTHER PTHR26402 3 216 7.0E-93 T 23-04-2016 DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 SUPERFAMILY SSF52172 3 134 5.69E-30 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 Gene3D G3DSA:1.10.10.10 126 215 1.4E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28235 332673b736190fcc6f06d2f0a9f953b5 228 SUPERFAMILY SSF46894 144 215 2.89E-21 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS20725 5c0f931bbbe3b26b3e4f56503e70fa8c 307 Pfam PF13614 AAA domain 30 206 6.3E-58 T 23-04-2016 IPR025669 AAA domain DC74_RS20725 5c0f931bbbe3b26b3e4f56503e70fa8c 307 Gene3D G3DSA:3.40.50.300 32 280 1.1E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS20725 5c0f931bbbe3b26b3e4f56503e70fa8c 307 PANTHER PTHR13696 9 290 1.4E-94 T 23-04-2016 DC74_RS20725 5c0f931bbbe3b26b3e4f56503e70fa8c 307 PANTHER PTHR13696:SF52 9 290 1.4E-94 T 23-04-2016 DC74_RS20725 5c0f931bbbe3b26b3e4f56503e70fa8c 307 SUPERFAMILY SSF52540 30 279 3.93E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06585 4bc2e2e1c584f53b4918e6eb7e26a0d9 285 Pfam PF04072 Leucine carboxyl methyltransferase 12 191 6.6E-48 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS06585 4bc2e2e1c584f53b4918e6eb7e26a0d9 285 PANTHER PTHR13600:SF12 6 260 4.4E-54 T 23-04-2016 DC74_RS06585 4bc2e2e1c584f53b4918e6eb7e26a0d9 285 Gene3D G3DSA:3.40.50.150 8 206 8.3E-19 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS06585 4bc2e2e1c584f53b4918e6eb7e26a0d9 285 SUPERFAMILY SSF53335 8 278 7.29E-63 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS06585 4bc2e2e1c584f53b4918e6eb7e26a0d9 285 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 10 262 2.2E-64 T 23-04-2016 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS06585 4bc2e2e1c584f53b4918e6eb7e26a0d9 285 PANTHER PTHR13600 6 260 4.4E-54 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS18880 75e67703173f787be7ce4ea9abbd4a2b 130 Pfam PF03733 Inner membrane component domain 4 54 4.9E-20 T 23-04-2016 IPR005185 Inner membrane component domain DC74_RS18880 75e67703173f787be7ce4ea9abbd4a2b 130 Pfam PF03733 Inner membrane component domain 68 118 2.5E-18 T 23-04-2016 IPR005185 Inner membrane component domain DC74_RS18880 75e67703173f787be7ce4ea9abbd4a2b 130 PANTHER PTHR31503 3 122 4.5E-40 T 23-04-2016 DC74_RS18880 75e67703173f787be7ce4ea9abbd4a2b 130 PIRSF PIRSF028777 1 130 1.3E-54 T 23-04-2016 IPR031308 Uncharacterised conserved protein UCP028777 DC74_RS36875 6f1e45f9f3e7a59e700d70b993ae1a3a 352 Pfam PF01497 Periplasmic binding protein 85 315 9.1E-28 T 23-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 DC74_RS36875 6f1e45f9f3e7a59e700d70b993ae1a3a 352 Gene3D G3DSA:3.40.50.1980 80 182 2.5E-19 T 23-04-2016 DC74_RS36875 6f1e45f9f3e7a59e700d70b993ae1a3a 352 Gene3D G3DSA:3.40.50.1980 183 338 1.8E-15 T 23-04-2016 DC74_RS36875 6f1e45f9f3e7a59e700d70b993ae1a3a 352 PANTHER PTHR30535 59 342 1.0E-94 T 23-04-2016 DC74_RS36875 6f1e45f9f3e7a59e700d70b993ae1a3a 352 SUPERFAMILY SSF53807 80 338 1.47E-40 T 23-04-2016 DC74_RS36875 6f1e45f9f3e7a59e700d70b993ae1a3a 352 PANTHER PTHR30535:SF4 59 342 1.0E-94 T 23-04-2016 DC74_RS20885 4e19a522b4a57e6e9c4312f76c6dd17b 452 Gene3D G3DSA:3.40.710.10 17 329 1.0E-68 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS20885 4e19a522b4a57e6e9c4312f76c6dd17b 452 PANTHER PTHR22935 3 348 2.9E-61 T 23-04-2016 DC74_RS20885 4e19a522b4a57e6e9c4312f76c6dd17b 452 SUPERFAMILY SSF56601 16 316 1.31E-65 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS20885 4e19a522b4a57e6e9c4312f76c6dd17b 452 Pfam PF00144 Beta-lactamase 17 325 6.5E-54 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS29205 9b5ecb89062adde87dafde819ef3fe34 191 Pfam PF13527 Acetyltransferase (GNAT) domain 57 142 3.3E-11 T 23-04-2016 DC74_RS29205 9b5ecb89062adde87dafde819ef3fe34 191 SUPERFAMILY SSF55729 15 191 2.16E-31 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS29205 9b5ecb89062adde87dafde819ef3fe34 191 Gene3D G3DSA:3.40.630.30 17 191 4.1E-60 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS00295 7cd24cf64247abbdd0ece4851c1e8ab1 234 PANTHER PTHR30055:SF93 15 141 1.9E-32 T 23-04-2016 DC74_RS00295 7cd24cf64247abbdd0ece4851c1e8ab1 234 SUPERFAMILY SSF48498 94 231 5.67E-25 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS00295 7cd24cf64247abbdd0ece4851c1e8ab1 234 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 92 228 3.8E-17 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS00295 7cd24cf64247abbdd0ece4851c1e8ab1 234 PANTHER PTHR30055 15 141 1.9E-32 T 23-04-2016 DC74_RS00295 7cd24cf64247abbdd0ece4851c1e8ab1 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 76 6.6E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00295 7cd24cf64247abbdd0ece4851c1e8ab1 234 SUPERFAMILY SSF46689 21 83 1.95E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00295 7cd24cf64247abbdd0ece4851c1e8ab1 234 Gene3D G3DSA:1.10.357.10 18 232 2.1E-52 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS22020 e6730abe75ebd0033fca11bad3574238 460 Pfam PF02374 Anion-transporting ATPase 26 298 3.2E-27 T 23-04-2016 IPR025723 Anion-transporting ATPase-like domain DC74_RS22020 e6730abe75ebd0033fca11bad3574238 460 SUPERFAMILY SSF52540 24 196 1.09E-33 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22020 e6730abe75ebd0033fca11bad3574238 460 SUPERFAMILY SSF52540 238 299 1.09E-33 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22020 e6730abe75ebd0033fca11bad3574238 460 Gene3D G3DSA:3.40.50.300 22 184 2.2E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22020 e6730abe75ebd0033fca11bad3574238 460 Gene3D G3DSA:3.40.50.300 225 330 2.2E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22020 e6730abe75ebd0033fca11bad3574238 460 PANTHER PTHR10803 17 297 1.9E-52 T 23-04-2016 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 DC74_RS08120 70dcbedfe27a7bc3f901e32d7d564c7d 110 Pfam PF06947 Protein of unknown function (DUF1290) 21 108 9.8E-35 T 23-04-2016 IPR009709 Protein of unknown function DUF1290 DC74_RS08120 70dcbedfe27a7bc3f901e32d7d564c7d 110 PIRSF PIRSF018579 1 110 2.4E-46 T 23-04-2016 IPR009709 Protein of unknown function DUF1290 DC74_RS05175 6101458b555e713ee9dd6eea13ecf98c 515 Pfam PF00437 Type II/IV secretion system protein 142 405 6.9E-75 T 23-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 DC74_RS05175 6101458b555e713ee9dd6eea13ecf98c 515 Gene3D G3DSA:3.30.450.90 112 238 6.6E-47 T 23-04-2016 DC74_RS05175 6101458b555e713ee9dd6eea13ecf98c 515 SUPERFAMILY SSF160246 2 98 2.88E-17 T 23-04-2016 DC74_RS05175 6101458b555e713ee9dd6eea13ecf98c 515 PANTHER PTHR30258 1 509 2.7E-171 T 23-04-2016 DC74_RS05175 6101458b555e713ee9dd6eea13ecf98c 515 SUPERFAMILY SSF52540 127 509 8.01E-94 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05175 6101458b555e713ee9dd6eea13ecf98c 515 Gene3D G3DSA:3.40.50.300 242 512 9.6E-92 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05175 6101458b555e713ee9dd6eea13ecf98c 515 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 1 100 5.6E-21 T 23-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 DC74_RS05175 6101458b555e713ee9dd6eea13ecf98c 515 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 333 347 - T 23-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 DC74_RS05175 6101458b555e713ee9dd6eea13ecf98c 515 PANTHER PTHR30258:SF1 1 509 2.7E-171 T 23-04-2016 DC74_RS08475 7aafc35f4671f776c578f301b94c1255 254 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 139 245 6.4E-7 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS08475 7aafc35f4671f776c578f301b94c1255 254 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 119 1.8E-5 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS08475 7aafc35f4671f776c578f301b94c1255 254 PANTHER PTHR33993 2 254 1.6E-93 T 23-04-2016 DC74_RS08475 7aafc35f4671f776c578f301b94c1255 254 SUPERFAMILY SSF54593 139 249 2.01E-21 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS08475 7aafc35f4671f776c578f301b94c1255 254 SUPERFAMILY SSF54593 11 167 4.16E-23 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS08475 7aafc35f4671f776c578f301b94c1255 254 PANTHER PTHR33993:SF2 2 254 1.6E-93 T 23-04-2016 DC74_RS08475 7aafc35f4671f776c578f301b94c1255 254 Gene3D G3DSA:3.10.180.10 139 250 2.2E-32 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS08475 7aafc35f4671f776c578f301b94c1255 254 Gene3D G3DSA:3.10.180.10 11 125 5.3E-33 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS25325 87d4e63130e7f8b4232c319819ef4eb3 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 2.5E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS25325 87d4e63130e7f8b4232c319819ef4eb3 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 2.5E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS25325 87d4e63130e7f8b4232c319819ef4eb3 207 Gene3D G3DSA:1.10.357.10 72 205 2.9E-35 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS25325 87d4e63130e7f8b4232c319819ef4eb3 207 PANTHER PTHR30055:SF10 16 205 5.4E-37 T 23-04-2016 DC74_RS25325 87d4e63130e7f8b4232c319819ef4eb3 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 74 3.5E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS25325 87d4e63130e7f8b4232c319819ef4eb3 207 PANTHER PTHR30055 16 205 5.4E-37 T 23-04-2016 DC74_RS25325 87d4e63130e7f8b4232c319819ef4eb3 207 Gene3D G3DSA:1.10.10.60 19 71 4.5E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS25325 87d4e63130e7f8b4232c319819ef4eb3 207 SUPERFAMILY SSF46689 17 74 2.19E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS20480 b448f15fe91279a8fd92f8272cdfdf1f 165 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 18 164 3.1E-54 T 23-04-2016 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit UniPathway: UPA00930 DC74_RS20480 b448f15fe91279a8fd92f8272cdfdf1f 165 Pfam PF01883 Domain of unknown function DUF59 16 83 5.7E-12 T 23-04-2016 IPR002744 Domain of unknown function DUF59 DC74_RS20480 b448f15fe91279a8fd92f8272cdfdf1f 165 SUPERFAMILY SSF117916 5 101 7.52E-21 T 23-04-2016 DC74_RS21805 7ea7ceb8a484a581dc23d3834687dc1a 163 Pfam PF01037 Lrp/AsnC ligand binding domain 74 144 8.2E-15 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS21805 7ea7ceb8a484a581dc23d3834687dc1a 163 Pfam PF13404 AsnC-type helix-turn-helix domain 9 49 2.9E-17 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21805 7ea7ceb8a484a581dc23d3834687dc1a 163 SUPERFAMILY SSF46785 8 68 5.96E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21805 7ea7ceb8a484a581dc23d3834687dc1a 163 SMART SM00344 8 115 1.7E-32 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS21805 7ea7ceb8a484a581dc23d3834687dc1a 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 9.7E-13 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21805 7ea7ceb8a484a581dc23d3834687dc1a 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 9.7E-13 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21805 7ea7ceb8a484a581dc23d3834687dc1a 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 9.7E-13 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS21805 7ea7ceb8a484a581dc23d3834687dc1a 163 Gene3D G3DSA:3.30.70.920 62 140 8.9E-19 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS21805 7ea7ceb8a484a581dc23d3834687dc1a 163 PANTHER PTHR30154 1 147 7.0E-78 T 23-04-2016 DC74_RS21805 7ea7ceb8a484a581dc23d3834687dc1a 163 PANTHER PTHR30154:SF26 1 147 7.0E-78 T 23-04-2016 DC74_RS21805 7ea7ceb8a484a581dc23d3834687dc1a 163 SUPERFAMILY SSF54909 71 147 1.61E-14 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS21805 7ea7ceb8a484a581dc23d3834687dc1a 163 Gene3D G3DSA:1.10.10.10 9 59 1.9E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS15915 317b7d5a1541ef0047ca10cdb25d2c55 318 SUPERFAMILY SSF51569 20 315 9.38E-72 T 23-04-2016 DC74_RS15915 317b7d5a1541ef0047ca10cdb25d2c55 318 Gene3D G3DSA:3.20.20.70 22 309 2.8E-82 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS15915 317b7d5a1541ef0047ca10cdb25d2c55 318 PANTHER PTHR10277 11 315 3.3E-161 T 23-04-2016 DC74_RS15915 317b7d5a1541ef0047ca10cdb25d2c55 318 PANTHER PTHR10277:SF1 11 315 3.3E-161 T 23-04-2016 DC74_RS15915 317b7d5a1541ef0047ca10cdb25d2c55 318 Pfam PF00682 HMGL-like 23 295 1.0E-47 T 23-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 DC74_RS26600 75c21f50f4d7199fe564fc3236802f86 319 PANTHER PTHR30346:SF6 1 311 1.1E-67 T 23-04-2016 DC74_RS26600 75c21f50f4d7199fe564fc3236802f86 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.6E-17 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS26600 75c21f50f4d7199fe564fc3236802f86 319 SUPERFAMILY SSF46785 3 108 3.48E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26600 75c21f50f4d7199fe564fc3236802f86 319 Gene3D G3DSA:1.10.10.10 4 86 3.2E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26600 75c21f50f4d7199fe564fc3236802f86 319 PANTHER PTHR30346 1 311 1.1E-67 T 23-04-2016 DC74_RS26600 75c21f50f4d7199fe564fc3236802f86 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.3E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS26600 75c21f50f4d7199fe564fc3236802f86 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.3E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS26600 75c21f50f4d7199fe564fc3236802f86 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.3E-6 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS26600 75c21f50f4d7199fe564fc3236802f86 319 Gene3D G3DSA:3.40.190.10 90 186 3.1E-11 T 23-04-2016 DC74_RS26600 75c21f50f4d7199fe564fc3236802f86 319 Pfam PF03466 LysR substrate binding domain 91 289 4.4E-21 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS26600 75c21f50f4d7199fe564fc3236802f86 319 SUPERFAMILY SSF53850 94 297 9.77E-18 T 23-04-2016 DC74_RS26600 75c21f50f4d7199fe564fc3236802f86 319 Gene3D G3DSA:3.40.190.10 187 265 5.5E-8 T 23-04-2016 DC74_RS35070 3af882d9bb6169b1c48e1694c93a6135 421 PANTHER PTHR23513 9 421 7.3E-55 T 23-04-2016 DC74_RS35070 3af882d9bb6169b1c48e1694c93a6135 421 SUPERFAMILY SSF103473 9 393 1.09E-38 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS35070 3af882d9bb6169b1c48e1694c93a6135 421 Pfam PF05977 Transmembrane secretion effector 12 400 6.0E-29 T 23-04-2016 IPR010290 Transmembrane secretion effector DC74_RS35070 3af882d9bb6169b1c48e1694c93a6135 421 Gene3D G3DSA:1.20.1250.20 10 190 4.8E-18 T 23-04-2016 DC74_RS35070 3af882d9bb6169b1c48e1694c93a6135 421 Gene3D G3DSA:1.20.1250.20 217 401 1.9E-8 T 23-04-2016 DC74_RS21675 f6c2f2fc37ea4346541cc752f47afd00 224 Gene3D G3DSA:1.10.1740.10 64 138 1.9E-13 T 23-04-2016 DC74_RS21675 f6c2f2fc37ea4346541cc752f47afd00 224 Pfam PF04545 Sigma-70, region 4 169 216 1.9E-14 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21675 f6c2f2fc37ea4346541cc752f47afd00 224 Gene3D G3DSA:1.10.10.10 160 222 9.1E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21675 f6c2f2fc37ea4346541cc752f47afd00 224 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 66 223 4.2E-42 T 23-04-2016 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 DC74_RS21675 f6c2f2fc37ea4346541cc752f47afd00 224 PANTHER PTHR30173 69 223 3.4E-32 T 23-04-2016 DC74_RS21675 f6c2f2fc37ea4346541cc752f47afd00 224 SUPERFAMILY SSF88946 64 147 7.06E-13 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21675 f6c2f2fc37ea4346541cc752f47afd00 224 Pfam PF04542 Sigma-70 region 2 70 137 7.0E-8 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21675 f6c2f2fc37ea4346541cc752f47afd00 224 SUPERFAMILY SSF88659 147 222 1.76E-16 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS21675 f6c2f2fc37ea4346541cc752f47afd00 224 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 68 219 2.4E-23 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS02740 cbcf4e585635b9484f2c6e63f12f1bb2 393 Pfam PF01070 FMN-dependent dehydrogenase 25 369 6.2E-134 T 23-04-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 DC74_RS02740 cbcf4e585635b9484f2c6e63f12f1bb2 393 SUPERFAMILY SSF51395 16 368 4.4E-99 T 23-04-2016 DC74_RS02740 cbcf4e585635b9484f2c6e63f12f1bb2 393 Gene3D G3DSA:3.20.20.70 16 370 2.5E-142 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS02740 cbcf4e585635b9484f2c6e63f12f1bb2 393 PIRSF PIRSF000138 3 372 1.6E-133 T 23-04-2016 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 DC74_RS02740 cbcf4e585635b9484f2c6e63f12f1bb2 393 PANTHER PTHR10578 13 393 6.6E-168 T 23-04-2016 DC74_RS02330 289c6aed1921d758b4c3f360e27e1f56 258 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 34 256 2.6E-105 T 23-04-2016 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|UniPathway: UPA00157 DC74_RS02330 289c6aed1921d758b4c3f360e27e1f56 258 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 30 56 3.9E-10 T 23-04-2016 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|UniPathway: UPA00157 DC74_RS02330 289c6aed1921d758b4c3f360e27e1f56 258 SUPERFAMILY SSF49482 33 255 1.57E-64 T 23-04-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 DC74_RS02330 289c6aed1921d758b4c3f360e27e1f56 258 PANTHER PTHR33711 1 258 3.6E-115 T 23-04-2016 DC74_RS02330 289c6aed1921d758b4c3f360e27e1f56 258 Pfam PF00775 Dioxygenase 69 248 2.2E-54 T 23-04-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 DC74_RS02330 289c6aed1921d758b4c3f360e27e1f56 258 Gene3D G3DSA:2.60.130.10 35 256 4.1E-70 T 23-04-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 DC74_RS02330 289c6aed1921d758b4c3f360e27e1f56 258 PANTHER PTHR33711:SF1 1 258 3.6E-115 T 23-04-2016 DC74_RS02330 289c6aed1921d758b4c3f360e27e1f56 258 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 99 127 - T 23-04-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 DC74_RS17465 3c69d20d2efc0d838804526080188f66 335 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 173 306 8.8E-8 T 23-04-2016 IPR018958 SMI1/KNR4-like domain DC74_RS17465 3c69d20d2efc0d838804526080188f66 335 Gene3D G3DSA:3.40.1580.10 170 202 2.0E-5 T 23-04-2016 IPR018958 SMI1/KNR4-like domain DC74_RS17465 3c69d20d2efc0d838804526080188f66 335 SMART SM00860 170 307 1.2E-4 T 23-04-2016 IPR018958 SMI1/KNR4-like domain DC74_RS17465 3c69d20d2efc0d838804526080188f66 335 SUPERFAMILY SSF160631 163 307 6.02E-16 T 23-04-2016 DC74_RS17465 3c69d20d2efc0d838804526080188f66 335 Pfam PF14414 A nuclease of the HNH/ENDO VII superfamily with conserved WHH 106 141 2.5E-11 T 23-04-2016 IPR032869 WHH domain-containing protein DC74_RS40495 a6143ac967841751c37284b65bdcaf11 488 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 397 455 2.1E-12 T 23-04-2016 IPR032821 Ketoacyl-synthetase, C-terminal extension DC74_RS40495 a6143ac967841751c37284b65bdcaf11 488 SMART SM00825 Beta-ketoacyl synthase 21 447 4.7E-173 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS40495 a6143ac967841751c37284b65bdcaf11 488 SUPERFAMILY SSF53901 422 443 7.09E-77 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40495 a6143ac967841751c37284b65bdcaf11 488 SUPERFAMILY SSF53901 16 135 7.09E-77 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40495 a6143ac967841751c37284b65bdcaf11 488 SUPERFAMILY SSF53901 165 390 7.09E-77 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40495 a6143ac967841751c37284b65bdcaf11 488 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 182 198 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS40495 a6143ac967841751c37284b65bdcaf11 488 PANTHER PTHR11712 1 447 3.4E-178 T 23-04-2016 DC74_RS40495 a6143ac967841751c37284b65bdcaf11 488 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 277 394 2.7E-41 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS40495 a6143ac967841751c37284b65bdcaf11 488 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 19 269 6.1E-69 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS40495 a6143ac967841751c37284b65bdcaf11 488 Gene3D G3DSA:3.40.47.10 282 445 5.4E-60 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS40495 a6143ac967841751c37284b65bdcaf11 488 PANTHER PTHR11712:SF288 1 447 3.4E-178 T 23-04-2016 DC74_RS40495 a6143ac967841751c37284b65bdcaf11 488 Gene3D G3DSA:3.40.47.10 21 281 9.0E-76 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS20445 b2b4ed26034752845b226e9ba683e8ac 560 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 7 560 1.7E-294 T 23-04-2016 IPR011975 Phenylacetic acid degradation protein PaaN2 DC74_RS20445 b2b4ed26034752845b226e9ba683e8ac 560 PANTHER PTHR11699:SF165 91 526 5.4E-188 T 23-04-2016 DC74_RS20445 b2b4ed26034752845b226e9ba683e8ac 560 SUPERFAMILY SSF53720 69 536 1.96E-58 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS20445 b2b4ed26034752845b226e9ba683e8ac 560 PANTHER PTHR11699 91 526 5.4E-188 T 23-04-2016 DC74_RS20445 b2b4ed26034752845b226e9ba683e8ac 560 Gene3D G3DSA:3.40.309.10 314 521 8.5E-28 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS20445 b2b4ed26034752845b226e9ba683e8ac 560 Gene3D G3DSA:3.40.605.10 91 305 3.9E-29 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS20445 b2b4ed26034752845b226e9ba683e8ac 560 Pfam PF00171 Aldehyde dehydrogenase family 91 476 1.3E-34 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 Gene3D G3DSA:3.30.390.30 344 415 5.0E-18 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 PANTHER PTHR22912 5 407 3.2E-77 T 23-04-2016 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 Gene3D G3DSA:3.50.50.60 110 243 1.6E-29 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 Pfam PF14759 Reductase C-terminal 344 415 3.8E-10 T 23-04-2016 IPR028202 Reductase, C-terminal DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 SUPERFAMILY SSF51905 13 329 1.17E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 SUPERFAMILY SSF55424 337 415 9.48E-20 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 Gene3D G3DSA:3.50.50.60 9 109 1.3E-19 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 PANTHER PTHR22912:SF180 5 407 3.2E-77 T 23-04-2016 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 3.8E-11 T 23-04-2016 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 3.8E-11 T 23-04-2016 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 3.8E-11 T 23-04-2016 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 244 258 3.8E-11 T 23-04-2016 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 321 1.9E-41 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 Gene3D G3DSA:3.50.50.60 244 332 2.6E-8 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 5.4E-12 T 23-04-2016 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 5.4E-12 T 23-04-2016 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 5.4E-12 T 23-04-2016 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 5.4E-12 T 23-04-2016 DC74_RS03325 fe0768332f7f61d1f930143061423af2 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 5.4E-12 T 23-04-2016 DC74_RS32920 5441fba146a67e048f6bf2f91ea1d6aa 202 SUPERFAMILY SSF48498 82 198 4.11E-17 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS32920 5441fba146a67e048f6bf2f91ea1d6aa 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 58 2.1E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS32920 5441fba146a67e048f6bf2f91ea1d6aa 202 PANTHER PTHR30055 1 201 3.1E-23 T 23-04-2016 DC74_RS32920 5441fba146a67e048f6bf2f91ea1d6aa 202 Gene3D G3DSA:1.10.357.10 2 198 1.2E-44 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS32920 5441fba146a67e048f6bf2f91ea1d6aa 202 SUPERFAMILY SSF46689 2 74 3.79E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS32920 5441fba146a67e048f6bf2f91ea1d6aa 202 Pfam PF13977 Bacterial transcriptional repressor 85 197 1.9E-16 T 23-04-2016 DC74_RS09940 69ffa892e450cf5f7dfdfbc40c1eb7a7 153 PANTHER PTHR33164 21 153 7.9E-38 T 23-04-2016 DC74_RS09940 69ffa892e450cf5f7dfdfbc40c1eb7a7 153 SUPERFAMILY SSF46785 9 153 1.79E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09940 69ffa892e450cf5f7dfdfbc40c1eb7a7 153 Pfam PF12802 MarR family 42 101 9.4E-10 T 23-04-2016 DC74_RS09940 69ffa892e450cf5f7dfdfbc40c1eb7a7 153 Gene3D G3DSA:1.10.10.10 17 152 2.4E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09940 69ffa892e450cf5f7dfdfbc40c1eb7a7 153 SMART SM00347 37 137 2.1E-12 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS09940 69ffa892e450cf5f7dfdfbc40c1eb7a7 153 PANTHER PTHR33164:SF9 21 153 7.9E-38 T 23-04-2016 DC74_RS39585 72f3f1a8cba384e330e2d4cf68a93c36 347 SMART SM00331 121 342 3.4E-32 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS39585 72f3f1a8cba384e330e2d4cf68a93c36 347 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 149 342 6.4E-39 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS39585 72f3f1a8cba384e330e2d4cf68a93c36 347 PANTHER PTHR21021 88 345 3.1E-28 T 23-04-2016 DC74_RS39585 72f3f1a8cba384e330e2d4cf68a93c36 347 SUPERFAMILY SSF81606 136 343 1.83E-10 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS00850 59bac82f062c91a7b12eebb5ce9e4965 900 Gene3D G3DSA:3.50.30.10 818 894 1.4E-23 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS00850 59bac82f062c91a7b12eebb5ce9e4965 900 Pfam PF00391 PEP-utilising enzyme, mobile domain 819 890 1.7E-20 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS00850 59bac82f062c91a7b12eebb5ce9e4965 900 PANTHER PTHR22931 804 892 6.8E-75 T 23-04-2016 DC74_RS00850 59bac82f062c91a7b12eebb5ce9e4965 900 PANTHER PTHR22931:SF7 804 892 6.8E-75 T 23-04-2016 DC74_RS00850 59bac82f062c91a7b12eebb5ce9e4965 900 SUPERFAMILY SSF56059 14 325 1.77E-48 T 23-04-2016 DC74_RS00850 59bac82f062c91a7b12eebb5ce9e4965 900 Gene3D G3DSA:3.30.1490.20 14 187 2.0E-34 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS00850 59bac82f062c91a7b12eebb5ce9e4965 900 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 321 2.6E-55 T 23-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 DC74_RS00850 59bac82f062c91a7b12eebb5ce9e4965 900 Gene3D G3DSA:3.30.470.20 188 323 6.6E-32 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS00850 59bac82f062c91a7b12eebb5ce9e4965 900 PANTHER PTHR22931:SF7 16 373 6.8E-75 T 23-04-2016 DC74_RS00850 59bac82f062c91a7b12eebb5ce9e4965 900 PANTHER PTHR22931 16 373 6.8E-75 T 23-04-2016 DC74_RS00850 59bac82f062c91a7b12eebb5ce9e4965 900 SUPERFAMILY SSF52009 793 894 4.71E-25 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DC74_RS20455 f92c611bfb772a5a5b4c4408607e154e 453 PANTHER PTHR39535 268 445 5.0E-81 T 23-04-2016 DC74_RS20455 f92c611bfb772a5a5b4c4408607e154e 453 PANTHER PTHR39535 7 244 5.0E-81 T 23-04-2016 DC74_RS20455 f92c611bfb772a5a5b4c4408607e154e 453 SMART SM00752 51 405 2.9E-82 T 23-04-2016 IPR011020 HTTM DC74_RS22065 99a2d3ee07b5c3ce53d4f0b7c18a916b 399 Pfam PF02674 Colicin V production protein 4 148 6.3E-19 T 23-04-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 DC74_RS22065 99a2d3ee07b5c3ce53d4f0b7c18a916b 399 PANTHER PTHR22939 54 384 2.3E-98 T 23-04-2016 DC74_RS22065 99a2d3ee07b5c3ce53d4f0b7c18a916b 399 PANTHER PTHR22939:SF106 54 384 2.3E-98 T 23-04-2016 DC74_RS22065 99a2d3ee07b5c3ce53d4f0b7c18a916b 399 PRINTS PR00834 HtrA/DegQ protease family signature 329 346 4.9E-6 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS22065 99a2d3ee07b5c3ce53d4f0b7c18a916b 399 PRINTS PR00834 HtrA/DegQ protease family signature 250 270 4.9E-6 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS22065 99a2d3ee07b5c3ce53d4f0b7c18a916b 399 PRINTS PR00834 HtrA/DegQ protease family signature 228 240 4.9E-6 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 DC74_RS22065 99a2d3ee07b5c3ce53d4f0b7c18a916b 399 Gene3D G3DSA:2.40.10.10 292 382 2.4E-12 T 23-04-2016 DC74_RS22065 99a2d3ee07b5c3ce53d4f0b7c18a916b 399 SUPERFAMILY SSF50494 194 380 3.13E-32 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS22065 99a2d3ee07b5c3ce53d4f0b7c18a916b 399 Gene3D G3DSA:2.40.10.10 219 291 7.5E-12 T 23-04-2016 DC74_RS22065 99a2d3ee07b5c3ce53d4f0b7c18a916b 399 Pfam PF13365 Trypsin-like peptidase domain 220 358 1.9E-18 T 23-04-2016 DC74_RS12945 941e64ca24ac5a32240c27260e3895f0 117 Pfam PF01521 Iron-sulphur cluster biosynthesis 13 114 2.1E-19 T 23-04-2016 IPR000361 FeS cluster biogenesis DC74_RS12945 941e64ca24ac5a32240c27260e3895f0 117 SUPERFAMILY SSF89360 13 107 3.73E-28 T 23-04-2016 IPR000361 FeS cluster biogenesis DC74_RS12945 941e64ca24ac5a32240c27260e3895f0 117 PANTHER PTHR10072 13 117 3.4E-41 T 23-04-2016 DC74_RS12945 941e64ca24ac5a32240c27260e3895f0 117 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 13 117 1.1E-36 T 23-04-2016 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 DC74_RS12945 941e64ca24ac5a32240c27260e3895f0 117 Gene3D G3DSA:2.60.300.12 13 107 2.6E-29 T 23-04-2016 IPR000361 FeS cluster biogenesis DC74_RS12945 941e64ca24ac5a32240c27260e3895f0 117 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 99 116 - T 23-04-2016 IPR017870 FeS cluster insertion, C-terminal, conserved site DC74_RS06615 1448a649d29ec9cd155267f4815c59e7 263 SUPERFAMILY SSF53474 3 254 2.14E-58 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS06615 1448a649d29ec9cd155267f4815c59e7 263 PANTHER PTHR10992 4 254 1.7E-55 T 23-04-2016 DC74_RS06615 1448a649d29ec9cd155267f4815c59e7 263 Pfam PF12697 Alpha/beta hydrolase family 22 247 2.4E-21 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS06615 1448a649d29ec9cd155267f4815c59e7 263 Gene3D G3DSA:3.40.50.1820 4 254 3.4E-59 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34250 bdfc766ea462126ab2da76539f6acba9 235 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 58 193 8.4E-18 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34250 bdfc766ea462126ab2da76539f6acba9 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 3.2E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34250 bdfc766ea462126ab2da76539f6acba9 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 3.2E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34250 bdfc766ea462126ab2da76539f6acba9 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 3.2E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34250 bdfc766ea462126ab2da76539f6acba9 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 3.2E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS34250 bdfc766ea462126ab2da76539f6acba9 235 Gene3D G3DSA:1.10.150.240 24 90 4.0E-6 T 23-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 DC74_RS34250 bdfc766ea462126ab2da76539f6acba9 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 193 2.6E-33 T 23-04-2016 IPR023214 HAD-like domain DC74_RS34250 bdfc766ea462126ab2da76539f6acba9 235 SUPERFAMILY SSF56784 13 212 1.65E-54 T 23-04-2016 IPR023214 HAD-like domain DC74_RS34250 bdfc766ea462126ab2da76539f6acba9 235 Gene3D G3DSA:3.40.50.1000 13 23 3.8E-41 T 23-04-2016 IPR023214 HAD-like domain DC74_RS34250 bdfc766ea462126ab2da76539f6acba9 235 Gene3D G3DSA:3.40.50.1000 97 212 3.8E-41 T 23-04-2016 IPR023214 HAD-like domain DC74_RS34250 bdfc766ea462126ab2da76539f6acba9 235 PANTHER PTHR18901 13 195 5.4E-61 T 23-04-2016 DC74_RS16015 242f0f9cd67cb0455ef52d4d7f74bc79 412 PANTHER PTHR12526:SF400 2 409 8.8E-79 T 23-04-2016 DC74_RS16015 242f0f9cd67cb0455ef52d4d7f74bc79 412 PANTHER PTHR12526 2 409 8.8E-79 T 23-04-2016 DC74_RS16015 242f0f9cd67cb0455ef52d4d7f74bc79 412 SUPERFAMILY SSF53756 2 368 1.2E-67 T 23-04-2016 DC74_RS16015 242f0f9cd67cb0455ef52d4d7f74bc79 412 Pfam PF13439 Glycosyltransferase Family 4 12 170 1.1E-23 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain DC74_RS16015 242f0f9cd67cb0455ef52d4d7f74bc79 412 Pfam PF13692 Glycosyl transferases group 1 195 311 1.9E-13 T 23-04-2016 DC74_RS16015 242f0f9cd67cb0455ef52d4d7f74bc79 412 Gene3D G3DSA:3.40.50.2000 151 301 4.1E-23 T 23-04-2016 DC74_RS11585 a1e5ab2ec16b2fe91f019d7c7426364b 136 PANTHER PTHR39289 1 130 3.7E-49 T 23-04-2016 DC74_RS11585 a1e5ab2ec16b2fe91f019d7c7426364b 136 Pfam PF06339 Ectoine synthase 1 127 1.0E-54 T 23-04-2016 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00067 DC74_RS11585 a1e5ab2ec16b2fe91f019d7c7426364b 136 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 119 5.0E-59 T 23-04-2016 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00067 DC74_RS11585 a1e5ab2ec16b2fe91f019d7c7426364b 136 Hamap MF_01255 L-ectoine synthase [ectC]. 1 129 37.525 T 23-04-2016 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00067 DC74_RS11585 a1e5ab2ec16b2fe91f019d7c7426364b 136 PANTHER PTHR39289:SF1 1 130 3.7E-49 T 23-04-2016 DC74_RS11585 a1e5ab2ec16b2fe91f019d7c7426364b 136 Gene3D G3DSA:2.60.120.10 25 112 1.5E-11 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS11585 a1e5ab2ec16b2fe91f019d7c7426364b 136 SUPERFAMILY SSF51182 1 133 1.61E-19 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS06200 d66d15ef68a7f4ea4f632df2b32e7e08 330 Gene3D G3DSA:1.10.10.10 4 80 1.1E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06200 d66d15ef68a7f4ea4f632df2b32e7e08 330 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.4E-17 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS06200 d66d15ef68a7f4ea4f632df2b32e7e08 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.7E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS06200 d66d15ef68a7f4ea4f632df2b32e7e08 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.7E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS06200 d66d15ef68a7f4ea4f632df2b32e7e08 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.7E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS06200 d66d15ef68a7f4ea4f632df2b32e7e08 330 PANTHER PTHR30126 2 154 6.8E-23 T 23-04-2016 DC74_RS06200 d66d15ef68a7f4ea4f632df2b32e7e08 330 SUPERFAMILY SSF46785 5 87 1.36E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06880 0b23bedb62fb22565c0ce7d1ee1e7f00 403 PANTHER PTHR13789:SF251 6 360 2.0E-115 T 23-04-2016 DC74_RS06880 0b23bedb62fb22565c0ce7d1ee1e7f00 403 SUPERFAMILY SSF51905 5 170 2.98E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06880 0b23bedb62fb22565c0ce7d1ee1e7f00 403 SUPERFAMILY SSF51905 266 365 2.98E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06880 0b23bedb62fb22565c0ce7d1ee1e7f00 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 4.3E-12 T 23-04-2016 DC74_RS06880 0b23bedb62fb22565c0ce7d1ee1e7f00 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 4.3E-12 T 23-04-2016 DC74_RS06880 0b23bedb62fb22565c0ce7d1ee1e7f00 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 4.3E-12 T 23-04-2016 DC74_RS06880 0b23bedb62fb22565c0ce7d1ee1e7f00 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 4.3E-12 T 23-04-2016 DC74_RS06880 0b23bedb62fb22565c0ce7d1ee1e7f00 403 PANTHER PTHR13789 6 360 2.0E-115 T 23-04-2016 DC74_RS06880 0b23bedb62fb22565c0ce7d1ee1e7f00 403 Pfam PF01494 FAD binding domain 5 338 8.6E-20 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS06880 0b23bedb62fb22565c0ce7d1ee1e7f00 403 Gene3D G3DSA:3.50.50.60 267 341 1.3E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06880 0b23bedb62fb22565c0ce7d1ee1e7f00 403 Gene3D G3DSA:3.50.50.60 5 175 1.3E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS16150 8d2fe96b61d16fee266763c08043f1a5 129 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 14 111 1.2E-25 T 23-04-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 DC74_RS01585 9a742cc2d5f30964b6dab399356d9340 261 Pfam PF12746 GNAT acetyltransferase 147 247 1.9E-13 T 23-04-2016 IPR027365 GNAT acetyltransferase YdfB-like KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.- DC74_RS01585 9a742cc2d5f30964b6dab399356d9340 261 SUPERFAMILY SSF55729 37 248 3.3E-14 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS01585 9a742cc2d5f30964b6dab399356d9340 261 Gene3D G3DSA:3.40.630.30 121 247 8.5E-8 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS15475 89ba3c4d3bfd84d94bd15adb8ca404ef 178 SMART SM00507 70 119 4.5E-14 T 23-04-2016 IPR003615 HNH nuclease DC74_RS15475 89ba3c4d3bfd84d94bd15adb8ca404ef 178 PANTHER PTHR33877 3 169 2.5E-62 T 23-04-2016 DC74_RS15475 89ba3c4d3bfd84d94bd15adb8ca404ef 178 Pfam PF14279 HNH endonuclease 83 128 8.2E-14 T 23-04-2016 IPR029471 HNH endonuclease 5 DC74_RS22425 bb4d36443784d61e3d8a7848ce68283e 381 SUPERFAMILY SSF55486 9 373 2.42E-105 T 23-04-2016 DC74_RS22425 bb4d36443784d61e3d8a7848ce68283e 381 Pfam PF10103 Zinicin-like metallopeptidase 10 370 1.6E-120 T 23-04-2016 IPR018766 Zinicin-like metallopeptidase type 2 DC74_RS22425 bb4d36443784d61e3d8a7848ce68283e 381 PANTHER PTHR39420:SF1 9 378 3.4E-165 T 23-04-2016 DC74_RS22425 bb4d36443784d61e3d8a7848ce68283e 381 PANTHER PTHR39420 9 378 3.4E-165 T 23-04-2016 DC74_RS22425 bb4d36443784d61e3d8a7848ce68283e 381 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 10 374 1.0E-123 T 23-04-2016 IPR018766 Zinicin-like metallopeptidase type 2 DC74_RS22425 bb4d36443784d61e3d8a7848ce68283e 381 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 10 374 1.0E-139 T 23-04-2016 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated DC74_RS05375 81177b4dd8b614c4371df2c4956a9fa4 309 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 171 290 1.7E-17 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS05375 81177b4dd8b614c4371df2c4956a9fa4 309 PANTHER PTHR10909 167 233 2.1E-19 T 23-04-2016 DC74_RS05375 81177b4dd8b614c4371df2c4956a9fa4 309 SUPERFAMILY SSF47203 167 299 8.05E-25 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS05375 81177b4dd8b614c4371df2c4956a9fa4 309 PANTHER PTHR10909:SF10 167 233 2.1E-19 T 23-04-2016 DC74_RS05375 81177b4dd8b614c4371df2c4956a9fa4 309 Gene3D G3DSA:1.20.140.10 171 294 7.1E-23 T 23-04-2016 DC74_RS12020 dd5afbb157e8b6399ee50ac62b26b2fb 136 SUPERFAMILY SSF48452 6 112 1.33E-17 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS12020 dd5afbb157e8b6399ee50ac62b26b2fb 136 Gene3D G3DSA:1.25.40.10 14 110 1.8E-16 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS12020 dd5afbb157e8b6399ee50ac62b26b2fb 136 SMART SM00028 77 110 0.086 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS12020 dd5afbb157e8b6399ee50ac62b26b2fb 136 SMART SM00028 43 76 70.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS12020 dd5afbb157e8b6399ee50ac62b26b2fb 136 Pfam PF14559 Tetratricopeptide repeat 19 77 5.2E-6 T 23-04-2016 DC74_RS16010 1f73258e0a8bc05ab53c37781e8cc118 403 Pfam PF02397 Bacterial sugar transferase 230 393 6.1E-41 T 23-04-2016 IPR003362 Bacterial sugar transferase DC74_RS16010 1f73258e0a8bc05ab53c37781e8cc118 403 PANTHER PTHR30576:SF0 8 403 2.2E-75 T 23-04-2016 DC74_RS16010 1f73258e0a8bc05ab53c37781e8cc118 403 PANTHER PTHR30576 8 403 2.2E-75 T 23-04-2016 DC74_RS16010 1f73258e0a8bc05ab53c37781e8cc118 403 Pfam PF13727 CoA-binding domain 37 182 3.1E-6 T 23-04-2016 DC74_RS00240 f0a675a7c60f9dc45b1fab33c12acf69 447 Pfam PF13604 AAA domain 35 184 1.7E-12 T 23-04-2016 DC74_RS00240 f0a675a7c60f9dc45b1fab33c12acf69 447 Gene3D G3DSA:3.40.50.300 20 188 1.2E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00240 f0a675a7c60f9dc45b1fab33c12acf69 447 SUPERFAMILY SSF52540 274 401 1.13E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00240 f0a675a7c60f9dc45b1fab33c12acf69 447 SUPERFAMILY SSF52540 33 247 1.13E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28495 3a3f4907eb461371ad9fa83ce934c8c2 428 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 71 416 1.4E-83 T 23-04-2016 IPR023834 Type VII secretion system peptidase S8A, mycosin-1 DC74_RS28495 3a3f4907eb461371ad9fa83ce934c8c2 428 SUPERFAMILY SSF52743 61 347 1.22E-69 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS28495 3a3f4907eb461371ad9fa83ce934c8c2 428 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 85 96 - T 23-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site DC74_RS28495 3a3f4907eb461371ad9fa83ce934c8c2 428 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 285 295 - T 23-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site DC74_RS28495 3a3f4907eb461371ad9fa83ce934c8c2 428 PANTHER PTHR10795:SF419 60 346 3.8E-55 T 23-04-2016 DC74_RS28495 3a3f4907eb461371ad9fa83ce934c8c2 428 PRINTS PR00723 Subtilisin serine protease family (S8) signature 80 99 2.8E-16 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS28495 3a3f4907eb461371ad9fa83ce934c8c2 428 PRINTS PR00723 Subtilisin serine protease family (S8) signature 284 300 2.8E-16 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS28495 3a3f4907eb461371ad9fa83ce934c8c2 428 PRINTS PR00723 Subtilisin serine protease family (S8) signature 119 132 2.8E-16 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS28495 3a3f4907eb461371ad9fa83ce934c8c2 428 PANTHER PTHR10795 60 346 3.8E-55 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS28495 3a3f4907eb461371ad9fa83ce934c8c2 428 Pfam PF00082 Subtilase family 80 338 6.7E-41 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS28495 3a3f4907eb461371ad9fa83ce934c8c2 428 Gene3D G3DSA:3.40.50.200 56 347 9.2E-72 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS28495 3a3f4907eb461371ad9fa83ce934c8c2 428 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 123 133 - T 23-04-2016 IPR022398 Peptidase S8, subtilisin, His-active site DC74_RS05875 c564b7b84497fc248f7a0250818483b7 461 Pfam PF00083 Sugar (and other) transporter 50 461 1.8E-49 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS05875 c564b7b84497fc248f7a0250818483b7 461 PANTHER PTHR23511:SF10 34 461 7.3E-140 T 23-04-2016 DC74_RS05875 c564b7b84497fc248f7a0250818483b7 461 PRINTS PR00171 Sugar transporter signature 53 63 1.2E-6 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS05875 c564b7b84497fc248f7a0250818483b7 461 PRINTS PR00171 Sugar transporter signature 391 403 1.2E-6 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS05875 c564b7b84497fc248f7a0250818483b7 461 PRINTS PR00171 Sugar transporter signature 136 155 1.2E-6 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS05875 c564b7b84497fc248f7a0250818483b7 461 ProSitePatterns PS00217 Sugar transport proteins signature 2. 141 166 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS05875 c564b7b84497fc248f7a0250818483b7 461 SUPERFAMILY SSF103473 31 460 1.29E-70 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05875 c564b7b84497fc248f7a0250818483b7 461 PANTHER PTHR23511 34 461 7.3E-140 T 23-04-2016 DC74_RS05875 c564b7b84497fc248f7a0250818483b7 461 Gene3D G3DSA:1.20.1250.20 47 226 8.7E-25 T 23-04-2016 DC74_RS05875 c564b7b84497fc248f7a0250818483b7 461 Gene3D G3DSA:1.20.1250.20 275 457 1.4E-14 T 23-04-2016 DC74_RS18090 80410246e207aa72870a72f3f74bf574 238 PANTHER PTHR39168:SF1 9 233 7.4E-53 T 23-04-2016 DC74_RS18090 80410246e207aa72870a72f3f74bf574 238 SUPERFAMILY SSF46785 5 92 5.36E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18090 80410246e207aa72870a72f3f74bf574 238 Pfam PF12840 Helix-turn-helix domain 11 70 1.2E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18090 80410246e207aa72870a72f3f74bf574 238 Gene3D G3DSA:1.10.10.10 4 93 3.5E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS18090 80410246e207aa72870a72f3f74bf574 238 PANTHER PTHR39168 9 233 7.4E-53 T 23-04-2016 DC74_RS18090 80410246e207aa72870a72f3f74bf574 238 SMART SM00418 11 90 3.4E-10 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PANTHER PTHR24286:SF42 23 410 1.2E-99 T 23-04-2016 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PRINTS PR00359 B-class P450 signature 142 158 8.8E-27 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PRINTS PR00359 B-class P450 signature 298 325 8.8E-27 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PRINTS PR00359 B-class P450 signature 279 290 8.8E-27 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PRINTS PR00359 B-class P450 signature 357 368 8.8E-27 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PRINTS PR00359 B-class P450 signature 348 357 8.8E-27 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PRINTS PR00359 B-class P450 signature 93 104 8.8E-27 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PRINTS PR00359 B-class P450 signature 197 219 8.8E-27 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PANTHER PTHR24286 23 410 1.2E-99 T 23-04-2016 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 Pfam PF00067 Cytochrome P450 280 378 6.3E-14 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 Pfam PF00067 Cytochrome P450 210 268 1.2E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 Gene3D G3DSA:1.10.630.10 12 409 1.2E-114 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PRINTS PR00385 P450 superfamily signature 348 357 1.1E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PRINTS PR00385 P450 superfamily signature 357 368 1.1E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PRINTS PR00385 P450 superfamily signature 244 261 1.1E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 PRINTS PR00385 P450 superfamily signature 279 290 1.1E-6 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS14915 d7e5411c6f965b57dff90d0225b1eb33 410 SUPERFAMILY SSF48264 16 409 7.73E-89 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS01265 184c30524450ff68f4dcccaad2f1a15b 231 SUPERFAMILY SSF46785 5 206 3.33E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01265 184c30524450ff68f4dcccaad2f1a15b 231 Pfam PF12840 Helix-turn-helix domain 6 60 1.6E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01265 184c30524450ff68f4dcccaad2f1a15b 231 Gene3D G3DSA:1.10.10.10 4 82 4.0E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05185 051f64bbe0f38875d7969b92e7e9ab67 144 SUPERFAMILY SSF54523 18 100 6.59E-5 T 23-04-2016 DC74_RS01610 199aed7fd0aec5f37fb455806a273b6b 377 Pfam PF12902 Ferritin-like 70 264 3.6E-51 T 23-04-2016 DC74_RS01610 199aed7fd0aec5f37fb455806a273b6b 377 PANTHER PTHR34400:SF2 2 370 2.6E-126 T 23-04-2016 DC74_RS01610 199aed7fd0aec5f37fb455806a273b6b 377 Gene3D G3DSA:1.20.1260.10 68 134 3.3E-7 T 23-04-2016 IPR012347 Ferritin-related DC74_RS01610 199aed7fd0aec5f37fb455806a273b6b 377 PANTHER PTHR34400 2 370 2.6E-126 T 23-04-2016 DC74_RS01610 199aed7fd0aec5f37fb455806a273b6b 377 SUPERFAMILY SSF47240 68 133 4.64E-5 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS26085 1a2397b5c077a8ac636c23b201dc6462 213 PANTHER PTHR30328:SF28 1 213 1.7E-100 T 23-04-2016 DC74_RS26085 1a2397b5c077a8ac636c23b201dc6462 213 SUPERFAMILY SSF48498 92 204 3.24E-27 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS26085 1a2397b5c077a8ac636c23b201dc6462 213 Gene3D G3DSA:1.10.357.10 11 203 1.4E-42 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS26085 1a2397b5c077a8ac636c23b201dc6462 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 4.8E-17 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS26085 1a2397b5c077a8ac636c23b201dc6462 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.2E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS26085 1a2397b5c077a8ac636c23b201dc6462 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.2E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS26085 1a2397b5c077a8ac636c23b201dc6462 213 SUPERFAMILY SSF46689 12 94 3.54E-21 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS26085 1a2397b5c077a8ac636c23b201dc6462 213 PANTHER PTHR30328 1 213 1.7E-100 T 23-04-2016 DC74_RS15830 7c3ece42da9bc674727ae7209aef6175 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 3.7E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS15830 7c3ece42da9bc674727ae7209aef6175 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 3.7E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS15830 7c3ece42da9bc674727ae7209aef6175 212 SUPERFAMILY SSF46689 17 90 4.82E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS15830 7c3ece42da9bc674727ae7209aef6175 212 PANTHER PTHR30328 18 210 9.8E-51 T 23-04-2016 DC74_RS15830 7c3ece42da9bc674727ae7209aef6175 212 PANTHER PTHR30328:SF24 18 210 9.8E-51 T 23-04-2016 DC74_RS15830 7c3ece42da9bc674727ae7209aef6175 212 Gene3D G3DSA:1.10.10.60 17 70 2.7E-21 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS15830 7c3ece42da9bc674727ae7209aef6175 212 SUPERFAMILY SSF48498 99 207 5.29E-16 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS15830 7c3ece42da9bc674727ae7209aef6175 212 Gene3D G3DSA:1.10.357.10 71 209 3.2E-26 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS15830 7c3ece42da9bc674727ae7209aef6175 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 2.8E-18 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS05790 cb1436bda6a0950c35a8ebc1916fa8af 641 SUPERFAMILY SSF51905 89 243 2.33E-6 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS05790 cb1436bda6a0950c35a8ebc1916fa8af 641 SUPERFAMILY SSF51905 11 62 2.33E-6 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS05790 cb1436bda6a0950c35a8ebc1916fa8af 641 Pfam PF13454 FAD-NAD(P)-binding 17 186 1.9E-33 T 23-04-2016 DC74_RS05790 cb1436bda6a0950c35a8ebc1916fa8af 641 Gene3D G3DSA:3.50.50.60 15 191 9.2E-5 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37855 679c634708ecbae803ddcdfd490b10ac 314 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 13 313 2.8E-53 T 23-04-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin DC74_RS37855 679c634708ecbae803ddcdfd490b10ac 314 Gene3D G3DSA:3.30.1780.10 11 143 7.0E-47 T 23-04-2016 IPR023401 Ornithine cyclodeaminase, N-terminal DC74_RS37855 679c634708ecbae803ddcdfd490b10ac 314 PANTHER PTHR13812:SF19 3 314 1.4E-67 T 23-04-2016 DC74_RS37855 679c634708ecbae803ddcdfd490b10ac 314 Gene3D G3DSA:3.40.50.720 144 298 1.1E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37855 679c634708ecbae803ddcdfd490b10ac 314 SUPERFAMILY SSF51735 11 314 3.11E-76 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37855 679c634708ecbae803ddcdfd490b10ac 314 PANTHER PTHR13812 3 314 1.4E-67 T 23-04-2016 DC74_RS37855 679c634708ecbae803ddcdfd490b10ac 314 PIRSF PIRSF001439 3 314 7.2E-66 T 23-04-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin DC74_RS05970 19577d99881faf2df0187bd998e84ced 157 Pfam PF12724 Flavodoxin domain 6 83 4.2E-10 T 23-04-2016 IPR026816 Flavodoxin domain DC74_RS05970 19577d99881faf2df0187bd998e84ced 157 SUPERFAMILY SSF52218 1 150 3.39E-18 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS05970 19577d99881faf2df0187bd998e84ced 157 Gene3D G3DSA:3.40.50.360 1 151 4.3E-18 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS07300 3acee13939bd3352680423860a270338 484 SUPERFAMILY SSF52091 407 475 2.94E-5 T 23-04-2016 IPR002645 STAS domain DC74_RS07300 3acee13939bd3352680423860a270338 484 Pfam PF13466 STAS domain 423 478 1.5E-7 T 23-04-2016 IPR002645 STAS domain DC74_RS07300 3acee13939bd3352680423860a270338 484 PANTHER PTHR11814:SF123 3 474 9.9E-170 T 23-04-2016 DC74_RS07300 3acee13939bd3352680423860a270338 484 Pfam PF00916 Sulfate permease family 7 374 6.4E-59 T 23-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 DC74_RS07300 3acee13939bd3352680423860a270338 484 PANTHER PTHR11814 3 474 9.9E-170 T 23-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 DC74_RS18235 e20c92a9168d302bfff841fb43a0be69 521 Gene3D G3DSA:2.30.38.10 341 412 3.4E-22 T 23-04-2016 DC74_RS18235 e20c92a9168d302bfff841fb43a0be69 521 Pfam PF00501 AMP-binding enzyme 16 419 8.8E-74 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS18235 e20c92a9168d302bfff841fb43a0be69 521 Gene3D G3DSA:3.40.50.980 174 340 9.0E-29 T 23-04-2016 DC74_RS18235 e20c92a9168d302bfff841fb43a0be69 521 PANTHER PTHR24096 8 518 2.0E-105 T 23-04-2016 DC74_RS18235 e20c92a9168d302bfff841fb43a0be69 521 Gene3D G3DSA:3.30.300.30 414 519 1.2E-22 T 23-04-2016 DC74_RS18235 e20c92a9168d302bfff841fb43a0be69 521 Gene3D G3DSA:3.40.50.980 8 173 8.8E-26 T 23-04-2016 DC74_RS18235 e20c92a9168d302bfff841fb43a0be69 521 SUPERFAMILY SSF56801 2 519 3.66E-117 T 23-04-2016 DC74_RS18235 e20c92a9168d302bfff841fb43a0be69 521 ProSitePatterns PS00455 Putative AMP-binding domain signature. 167 178 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS18235 e20c92a9168d302bfff841fb43a0be69 521 Pfam PF13193 AMP-binding enzyme C-terminal domain 428 503 2.4E-13 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS16565 96af2952cbc27ad6fc00a7f536813080 657 Pfam PF01799 [2Fe-2S] binding domain 534 606 3.5E-23 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS16565 96af2952cbc27ad6fc00a7f536813080 657 PANTHER PTHR11908 459 610 1.2E-80 T 23-04-2016 DC74_RS16565 96af2952cbc27ad6fc00a7f536813080 657 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 500 508 - T 23-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DC74_RS16565 96af2952cbc27ad6fc00a7f536813080 657 SUPERFAMILY SSF54292 465 549 9.83E-19 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS16565 96af2952cbc27ad6fc00a7f536813080 657 Gene3D G3DSA:3.10.20.30 463 535 4.2E-25 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS16565 96af2952cbc27ad6fc00a7f536813080 657 PANTHER PTHR11908:SF95 459 610 1.2E-80 T 23-04-2016 DC74_RS16565 96af2952cbc27ad6fc00a7f536813080 657 SUPERFAMILY SSF47741 545 612 1.02E-25 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS16565 96af2952cbc27ad6fc00a7f536813080 657 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 479 514 5.1E-4 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS16565 96af2952cbc27ad6fc00a7f536813080 657 Gene3D G3DSA:1.10.150.120 536 617 6.6E-29 T 23-04-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DC74_RS39275 ea070ac883ad9d3bb1ce597fa9e855ae 330 Gene3D G3DSA:3.90.1580.10 68 329 1.7E-52 T 23-04-2016 IPR005532 Sulfatase-modifying factor enzyme DC74_RS39275 ea070ac883ad9d3bb1ce597fa9e855ae 330 PANTHER PTHR23150 27 329 6.0E-49 T 23-04-2016 DC74_RS39275 ea070ac883ad9d3bb1ce597fa9e855ae 330 SUPERFAMILY SSF56436 71 328 1.88E-54 T 23-04-2016 IPR016187 C-type lectin fold DC74_RS39275 ea070ac883ad9d3bb1ce597fa9e855ae 330 Pfam PF03781 Sulfatase-modifying factor enzyme 1 104 327 2.4E-45 T 23-04-2016 IPR005532 Sulfatase-modifying factor enzyme DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 1.5E-10 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 212 226 1.5E-10 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 1.5E-10 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 1.5E-10 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 Gene3D G3DSA:3.40.50.1820 13 267 2.3E-51 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 PRINTS PR00412 Epoxide hydrolase signature 107 120 3.0E-5 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 PRINTS PR00412 Epoxide hydrolase signature 242 264 3.0E-5 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 PRINTS PR00412 Epoxide hydrolase signature 93 106 3.0E-5 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 PRINTS PR00412 Epoxide hydrolase signature 49 64 3.0E-5 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 Pfam PF00561 alpha/beta hydrolase fold 26 250 5.4E-25 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 SUPERFAMILY SSF53474 10 267 3.19E-54 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 PANTHER PTHR10992 162 267 2.0E-42 T 23-04-2016 DC74_RS06620 4e88bec8aca78cca196f9a0f97d1ead9 292 PANTHER PTHR10992 17 133 2.0E-42 T 23-04-2016 DC74_RS28775 79b82e90fe9156284359f764a5734997 384 Pfam PF01594 Domain of unknown function DUF20 46 366 2.8E-75 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like DC74_RS28775 79b82e90fe9156284359f764a5734997 384 PANTHER PTHR21716 34 372 7.7E-62 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 Pfam PF00154 recA bacterial DNA recombination protein 8 269 9.2E-144 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 PANTHER PTHR22942:SF1 6 336 1.7E-203 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 325 5.1E-176 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 ProSitePatterns PS00321 recA signature. 214 222 - T 23-04-2016 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 SUPERFAMILY SSF52540 5 268 3.48E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 Gene3D G3DSA:3.30.250.10 269 327 3.2E-29 T 23-04-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 Hamap MF_00268 Protein RecA [recA]. 6 330 52.848 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 SUPERFAMILY SSF54752 269 327 2.49E-21 T 23-04-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 PANTHER PTHR22942 6 336 1.7E-203 T 23-04-2016 DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 PRINTS PR00142 RecA protein signature 166 195 1.5E-85 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 PRINTS PR00142 RecA protein signature 211 239 1.5E-85 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 PRINTS PR00142 RecA protein signature 128 157 1.5E-85 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 PRINTS PR00142 RecA protein signature 298 315 1.5E-85 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 PRINTS PR00142 RecA protein signature 94 123 1.5E-85 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 PRINTS PR00142 RecA protein signature 244 273 1.5E-85 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 Gene3D G3DSA:3.40.50.300 28 268 4.6E-89 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28780 216c219644d5a51e7b6060aea28bc67f 374 SMART SM00382 58 229 3.4E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS12100 d0597aaa722814b2edf3f9c8e9f578e3 572 PANTHER PTHR30482:SF10 237 571 1.2E-118 T 23-04-2016 DC74_RS12100 d0597aaa722814b2edf3f9c8e9f578e3 572 PANTHER PTHR30482 237 571 1.2E-118 T 23-04-2016 DC74_RS12100 d0597aaa722814b2edf3f9c8e9f578e3 572 Pfam PF02653 Branched-chain amino acid transport system / permease component 269 553 2.9E-40 T 23-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 DC74_RS13155 8f3c97a9d6b576eeccf102eef0005b6e 340 SUPERFAMILY SSF54368 5 84 1.44E-11 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13155 8f3c97a9d6b576eeccf102eef0005b6e 340 SUPERFAMILY SSF55931 87 338 9.81E-61 T 23-04-2016 DC74_RS13155 8f3c97a9d6b576eeccf102eef0005b6e 340 Gene3D G3DSA:3.30.590.10 88 338 3.0E-52 T 23-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 DC74_RS13155 8f3c97a9d6b576eeccf102eef0005b6e 340 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 216 232 - T 23-04-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13155 8f3c97a9d6b576eeccf102eef0005b6e 340 PANTHER PTHR20852:SF57 5 340 2.2E-163 T 23-04-2016 DC74_RS13155 8f3c97a9d6b576eeccf102eef0005b6e 340 Pfam PF00120 Glutamine synthetase, catalytic domain 88 233 3.7E-10 T 23-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13155 8f3c97a9d6b576eeccf102eef0005b6e 340 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 5 78 1.3E-14 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13155 8f3c97a9d6b576eeccf102eef0005b6e 340 PANTHER PTHR20852 5 340 2.2E-163 T 23-04-2016 DC74_RS13155 8f3c97a9d6b576eeccf102eef0005b6e 340 ProSitePatterns PS00180 Glutamine synthetase signature 1. 37 54 - T 23-04-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS13155 8f3c97a9d6b576eeccf102eef0005b6e 340 SMART SM01230 85 330 1.3E-48 T 23-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DC74_RS39690 72870eccaea939794c788b3a59adf66b 240 Gene3D G3DSA:3.40.50.1820 21 224 8.8E-20 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS39690 72870eccaea939794c788b3a59adf66b 240 SUPERFAMILY SSF53474 118 239 8.74E-20 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS39690 72870eccaea939794c788b3a59adf66b 240 SUPERFAMILY SSF53474 21 85 8.74E-20 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08485 5f8e72a01191cd2af4273695721de5aa 259 Pfam PF08241 Methyltransferase domain 49 123 5.0E-9 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS08485 5f8e72a01191cd2af4273695721de5aa 259 SUPERFAMILY SSF53335 15 167 4.39E-14 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS08485 5f8e72a01191cd2af4273695721de5aa 259 Gene3D G3DSA:3.40.50.150 15 146 1.4E-13 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS39760 2d0d58730e319dc91189ab5ca8766664 321 PANTHER PTHR23024 73 320 2.3E-68 T 23-04-2016 DC74_RS39760 2d0d58730e319dc91189ab5ca8766664 321 Pfam PF07859 alpha/beta hydrolase fold 88 294 5.0E-55 T 23-04-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 DC74_RS39760 2d0d58730e319dc91189ab5ca8766664 321 Gene3D G3DSA:3.40.50.1820 20 320 1.4E-82 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS39760 2d0d58730e319dc91189ab5ca8766664 321 SUPERFAMILY SSF53474 29 319 1.62E-64 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS39760 2d0d58730e319dc91189ab5ca8766664 321 PANTHER PTHR23024:SF144 73 320 2.3E-68 T 23-04-2016 DC74_RS20265 c5bfc79a270b2946c25a5c6737940085 317 PIRSF PIRSF006232 22 317 5.4E-87 T 23-04-2016 IPR012093 Pirin DC74_RS20265 c5bfc79a270b2946c25a5c6737940085 317 SUPERFAMILY SSF51182 24 314 6.62E-80 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS20265 c5bfc79a270b2946c25a5c6737940085 317 Pfam PF05726 Pirin C-terminal cupin domain 201 309 2.0E-28 T 23-04-2016 IPR008778 Pirin, C-terminal domain DC74_RS20265 c5bfc79a270b2946c25a5c6737940085 317 PANTHER PTHR13903:SF13 21 314 1.3E-161 T 23-04-2016 DC74_RS20265 c5bfc79a270b2946c25a5c6737940085 317 Pfam PF02678 Pirin 42 146 8.0E-31 T 23-04-2016 IPR003829 Pirin, N-terminal domain DC74_RS20265 c5bfc79a270b2946c25a5c6737940085 317 PANTHER PTHR13903 21 314 1.3E-161 T 23-04-2016 IPR012093 Pirin DC74_RS20265 c5bfc79a270b2946c25a5c6737940085 317 Gene3D G3DSA:2.60.120.10 24 282 3.0E-74 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 Gene3D G3DSA:1.25.40.10 544 565 4.5E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 Gene3D G3DSA:1.25.40.10 769 831 4.5E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 Gene3D G3DSA:1.25.40.10 650 726 4.5E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 SMART SM00421 842 899 1.2E-19 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 Pfam PF00196 Bacterial regulatory proteins, luxR family 844 897 3.9E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 SUPERFAMILY SSF46894 837 902 1.5E-16 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 SUPERFAMILY SSF48452 651 802 5.91E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 Pfam PF13191 AAA ATPase domain 5 149 4.8E-13 T 23-04-2016 DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 ProSitePatterns PS00622 LuxR-type HTH domain signature. 859 886 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 Gene3D G3DSA:1.10.10.10 842 900 1.5E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 859 875 4.4E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 875 887 4.4E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS39090 e935b5bb20bcfed0352dfeda73cd3abc 917 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 845 859 4.4E-9 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 SUPERFAMILY SSF52540 2 79 1.31E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 SUPERFAMILY SSF52540 128 233 1.31E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 SMART SM00382 350 516 1.1E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 SMART SM00382 26 232 1.6E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 Pfam PF12848 ABC transporter 230 304 1.4E-7 T 23-04-2016 IPR032781 ABC-transporter extension domain DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 Pfam PF00005 ABC transporter 19 187 9.7E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 Pfam PF00005 ABC transporter 342 471 1.5E-24 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 SUPERFAMILY SSF52540 330 516 7.26E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 Gene3D G3DSA:3.40.50.300 135 282 1.6E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 Gene3D G3DSA:3.40.50.300 327 516 1.3E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 Gene3D G3DSA:3.40.50.300 4 102 1.6E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 PANTHER PTHR19211:SF53 1 529 0.0 T 23-04-2016 DC74_RS11475 1321c2d75b82a030d2a775cb0d74d7b8 532 PANTHER PTHR19211 1 529 0.0 T 23-04-2016 DC74_RS00745 5ccdab875de3d4b91cc2750053b8f3e7 198 SUPERFAMILY SSF140959 5 195 1.44E-24 T 23-04-2016 DC74_RS10740 683edcad8be9b23e2a6ed8b1fd87050c 461 PANTHER PTHR24064 19 461 6.2E-77 T 23-04-2016 DC74_RS10740 683edcad8be9b23e2a6ed8b1fd87050c 461 Gene3D G3DSA:1.20.1250.20 274 459 2.6E-24 T 23-04-2016 DC74_RS10740 683edcad8be9b23e2a6ed8b1fd87050c 461 Gene3D G3DSA:1.20.1250.20 33 221 4.6E-24 T 23-04-2016 DC74_RS10740 683edcad8be9b23e2a6ed8b1fd87050c 461 SUPERFAMILY SSF103473 1 460 7.85E-74 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS10740 683edcad8be9b23e2a6ed8b1fd87050c 461 ProSitePatterns PS00217 Sugar transport proteins signature 2. 131 156 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS10740 683edcad8be9b23e2a6ed8b1fd87050c 461 Pfam PF00083 Sugar (and other) transporter 72 461 3.8E-39 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS10740 683edcad8be9b23e2a6ed8b1fd87050c 461 PANTHER PTHR24064:SF277 19 461 6.2E-77 T 23-04-2016 DC74_RS17645 5ac21b9e479e79749aff55a7e161887a 579 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 85 315 2.5E-21 T 23-04-2016 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 DC74_RS17645 5ac21b9e479e79749aff55a7e161887a 579 PANTHER PTHR10050 20 123 2.0E-53 T 23-04-2016 IPR027005 Glycosyltransferase 39-like DC74_RS17645 5ac21b9e479e79749aff55a7e161887a 579 PANTHER PTHR10050 277 358 2.0E-53 T 23-04-2016 IPR027005 Glycosyltransferase 39-like DC74_RS17645 5ac21b9e479e79749aff55a7e161887a 579 PANTHER PTHR10050 149 255 2.0E-53 T 23-04-2016 IPR027005 Glycosyltransferase 39-like DC74_RS17645 5ac21b9e479e79749aff55a7e161887a 579 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 386 578 1.1E-26 T 23-04-2016 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|MetaCyc: PWY-822|UniPathway: UPA00378 DC74_RS17645 5ac21b9e479e79749aff55a7e161887a 579 PANTHER PTHR10050:SF29 20 123 2.0E-53 T 23-04-2016 DC74_RS17645 5ac21b9e479e79749aff55a7e161887a 579 PANTHER PTHR10050:SF29 277 358 2.0E-53 T 23-04-2016 DC74_RS17645 5ac21b9e479e79749aff55a7e161887a 579 PANTHER PTHR10050:SF29 149 255 2.0E-53 T 23-04-2016 DC74_RS30715 c8a3ff4ce6d5f2b014245e78e9557c6a 415 PANTHER PTHR35010:SF2 1 272 6.4E-29 T 23-04-2016 DC74_RS30715 c8a3ff4ce6d5f2b014245e78e9557c6a 415 PANTHER PTHR35010 1 272 6.4E-29 T 23-04-2016 DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 Gene3D G3DSA:1.10.287.130 147 207 7.3E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 Pfam PF00512 His Kinase A (phospho-acceptor) domain 156 219 2.9E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 381 2.1E-21 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 SUPERFAMILY SSF47384 138 221 2.55E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 SMART SM00388 155 221 2.5E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 SUPERFAMILY SSF55874 211 379 1.05E-43 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 Gene3D G3DSA:3.30.565.10 208 380 1.3E-45 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 321 7.8E-21 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 360 7.8E-21 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 335 7.8E-21 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 379 7.8E-21 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 PANTHER PTHR24423 91 389 6.8E-82 T 23-04-2016 DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 PANTHER PTHR24423:SF394 91 389 6.8E-82 T 23-04-2016 DC74_RS23295 68be991d0eb7de7c735d265e1f0353bd 422 SMART SM00387 266 382 6.4E-37 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32900 7d5e197c0feb9bfea3a259322a2f1c59 260 Gene3D G3DSA:3.20.20.370 63 255 2.0E-49 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS32900 7d5e197c0feb9bfea3a259322a2f1c59 260 SUPERFAMILY SSF88713 63 255 3.64E-49 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS32900 7d5e197c0feb9bfea3a259322a2f1c59 260 Pfam PF01522 Polysaccharide deacetylase 70 192 9.9E-27 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS32900 7d5e197c0feb9bfea3a259322a2f1c59 260 PANTHER PTHR10587 73 256 8.7E-43 T 23-04-2016 DC74_RS11355 4ad6e95d8b8576c8d977b66a918e58f9 540 Pfam PF00474 Sodium:solute symporter family 47 463 3.4E-93 T 23-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS11355 4ad6e95d8b8576c8d977b66a918e58f9 540 PANTHER PTHR11819 16 534 1.4E-244 T 23-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS11355 4ad6e95d8b8576c8d977b66a918e58f9 540 PANTHER PTHR11819:SF13 16 534 1.4E-244 T 23-04-2016 DC74_RS11355 4ad6e95d8b8576c8d977b66a918e58f9 540 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 47 462 5.4E-58 T 23-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS01170 2b64a6462b9da4ad4b21f3aad25e8377 287 Gene3D G3DSA:3.40.50.620 3 136 4.7E-26 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS01170 2b64a6462b9da4ad4b21f3aad25e8377 287 Gene3D G3DSA:3.40.50.620 142 285 1.1E-20 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS01170 2b64a6462b9da4ad4b21f3aad25e8377 287 Pfam PF00582 Universal stress protein family 3 136 1.7E-19 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS01170 2b64a6462b9da4ad4b21f3aad25e8377 287 Pfam PF00582 Universal stress protein family 150 285 8.2E-14 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS01170 2b64a6462b9da4ad4b21f3aad25e8377 287 PANTHER PTHR31964 1 152 1.4E-24 T 23-04-2016 DC74_RS01170 2b64a6462b9da4ad4b21f3aad25e8377 287 PRINTS PR01438 Universal stress protein signature 2 20 1.0E-7 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS01170 2b64a6462b9da4ad4b21f3aad25e8377 287 PRINTS PR01438 Universal stress protein signature 96 108 1.0E-7 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS01170 2b64a6462b9da4ad4b21f3aad25e8377 287 PRINTS PR01438 Universal stress protein signature 114 136 1.0E-7 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS01170 2b64a6462b9da4ad4b21f3aad25e8377 287 SUPERFAMILY SSF52402 5 136 3.01E-24 T 23-04-2016 DC74_RS01170 2b64a6462b9da4ad4b21f3aad25e8377 287 PANTHER PTHR31964:SF42 1 152 1.4E-24 T 23-04-2016 DC74_RS01170 2b64a6462b9da4ad4b21f3aad25e8377 287 SUPERFAMILY SSF52402 147 285 5.19E-18 T 23-04-2016 DC74_RS29725 f6b2678d66bee14cafb6d64265b0cd58 291 SUPERFAMILY SSF161098 19 291 3.01E-70 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS29725 f6b2678d66bee14cafb6d64265b0cd58 291 Gene3D G3DSA:1.10.3720.10 10 279 4.9E-66 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS29725 f6b2678d66bee14cafb6d64265b0cd58 291 PANTHER PTHR32243 9 291 5.8E-100 T 23-04-2016 DC74_RS29725 f6b2678d66bee14cafb6d64265b0cd58 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 285 6.6E-22 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS29725 f6b2678d66bee14cafb6d64265b0cd58 291 PANTHER PTHR32243:SF24 9 291 5.8E-100 T 23-04-2016 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 Gene3D G3DSA:1.10.630.10 19 403 9.1E-124 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 Pfam PF00067 Cytochrome P450 53 372 3.5E-28 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00385 P450 superfamily signature 276 287 5.3E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00385 P450 superfamily signature 352 363 5.3E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00385 P450 superfamily signature 343 352 5.3E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00385 P450 superfamily signature 241 258 5.3E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00359 B-class P450 signature 162 177 3.4E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00359 B-class P450 signature 276 287 3.4E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00359 B-class P450 signature 98 109 3.4E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00359 B-class P450 signature 199 221 3.4E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00359 B-class P450 signature 294 321 3.4E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00359 B-class P450 signature 352 363 3.4E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00359 B-class P450 signature 145 161 3.4E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00359 B-class P450 signature 343 352 3.4E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PRINTS PR00359 B-class P450 signature 322 337 3.4E-57 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 SUPERFAMILY SSF48264 21 403 8.64E-95 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS21710 8af1283c38d946f0763c5f5559e53374 403 PANTHER PTHR11712 39 403 3.2E-92 T 23-04-2016 DC74_RS29445 a6b093bde8f515f4b979e375a7467b83 310 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 20 302 4.1E-38 T 23-04-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 DC74_RS29445 a6b093bde8f515f4b979e375a7467b83 310 PANTHER PTHR10696 23 305 5.8E-68 T 23-04-2016 DC74_RS29445 a6b093bde8f515f4b979e375a7467b83 310 Gene3D G3DSA:3.60.130.10 20 152 1.0E-55 T 23-04-2016 DC74_RS29445 a6b093bde8f515f4b979e375a7467b83 310 Gene3D G3DSA:3.60.130.10 184 305 1.0E-55 T 23-04-2016 DC74_RS29445 a6b093bde8f515f4b979e375a7467b83 310 PANTHER PTHR10696:SF27 23 305 5.8E-68 T 23-04-2016 DC74_RS29445 a6b093bde8f515f4b979e375a7467b83 310 SUPERFAMILY SSF51197 17 303 4.58E-72 T 23-04-2016 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 SUPERFAMILY SSF51905 5 170 1.36E-58 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 SUPERFAMILY SSF51905 269 361 1.36E-58 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 PANTHER PTHR13789 2 429 3.1E-97 T 23-04-2016 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 2.7E-47 T 23-04-2016 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 2.7E-47 T 23-04-2016 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.7E-47 T 23-04-2016 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 2.7E-47 T 23-04-2016 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 333 349 2.7E-47 T 23-04-2016 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 315 333 2.7E-47 T 23-04-2016 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 Gene3D G3DSA:3.50.50.60 3 160 2.7E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 Gene3D G3DSA:3.50.50.60 280 320 2.7E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 PANTHER PTHR13789:SF90 2 429 3.1E-97 T 23-04-2016 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 Pfam PF01494 FAD binding domain 5 347 9.9E-83 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 Gene3D G3DSA:3.30.9.10 330 355 1.5E-9 T 23-04-2016 DC74_RS03660 c3fb6e160395aec174a8cd42df35338d 508 Gene3D G3DSA:3.30.9.10 161 275 1.5E-9 T 23-04-2016 DC74_RS34295 1f73d08a348630dc6cb429ad55e9b343 242 Pfam PF07103 Protein of unknown function (DUF1365) 6 234 2.8E-64 T 23-04-2016 IPR010775 Protein of unknown function DUF1365 DC74_RS34295 1f73d08a348630dc6cb429ad55e9b343 242 PANTHER PTHR33973 4 234 3.7E-50 T 23-04-2016 DC74_RS36145 fe81e5094a57bd8d084e6c73c421bdfc 180 Hamap MF_00163 Peptide deformylase [def]. 2 172 20.107 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS36145 fe81e5094a57bd8d084e6c73c421bdfc 180 Pfam PF01327 Polypeptide deformylase 6 158 4.2E-33 T 23-04-2016 IPR023635 Peptide deformylase DC74_RS36145 fe81e5094a57bd8d084e6c73c421bdfc 180 PIRSF PIRSF004749 1 175 1.3E-31 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS36145 fe81e5094a57bd8d084e6c73c421bdfc 180 SUPERFAMILY SSF56420 5 172 3.53E-36 T 23-04-2016 IPR023635 Peptide deformylase DC74_RS36145 fe81e5094a57bd8d084e6c73c421bdfc 180 Gene3D G3DSA:3.90.45.10 6 172 5.0E-39 T 23-04-2016 IPR023635 Peptide deformylase DC74_RS36145 fe81e5094a57bd8d084e6c73c421bdfc 180 PANTHER PTHR10458 1 157 7.1E-32 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS36145 fe81e5094a57bd8d084e6c73c421bdfc 180 PRINTS PR01576 Peptide deformylase signature 42 71 1.3E-16 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS36145 fe81e5094a57bd8d084e6c73c421bdfc 180 PRINTS PR01576 Peptide deformylase signature 130 159 1.3E-16 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS36145 fe81e5094a57bd8d084e6c73c421bdfc 180 PRINTS PR01576 Peptide deformylase signature 99 110 1.3E-16 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS36145 fe81e5094a57bd8d084e6c73c421bdfc 180 PRINTS PR01576 Peptide deformylase signature 111 129 1.3E-16 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS26330 9f8ed0d2eb9888ee570d25156ea20fab 218 Gene3D G3DSA:1.10.357.10 3 189 3.1E-22 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS26330 9f8ed0d2eb9888ee570d25156ea20fab 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 1.8E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS26330 9f8ed0d2eb9888ee570d25156ea20fab 218 SUPERFAMILY SSF46689 4 71 6.48E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS26330 9f8ed0d2eb9888ee570d25156ea20fab 218 PANTHER PTHR30055 5 118 2.3E-34 T 23-04-2016 DC74_RS26330 9f8ed0d2eb9888ee570d25156ea20fab 218 PANTHER PTHR30055:SF8 5 118 2.3E-34 T 23-04-2016 DC74_RS11940 4ad622c6d9bec679da9a37a97609fbba 293 PANTHER PTHR23344:SF20 35 288 4.7E-72 T 23-04-2016 DC74_RS11940 4ad622c6d9bec679da9a37a97609fbba 293 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 40 282 3.8E-41 T 23-04-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 DC74_RS11940 4ad622c6d9bec679da9a37a97609fbba 293 SUPERFAMILY SSF51695 34 288 7.59E-68 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS11940 4ad622c6d9bec679da9a37a97609fbba 293 PANTHER PTHR23344 35 288 4.7E-72 T 23-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 DC74_RS11940 4ad622c6d9bec679da9a37a97609fbba 293 Gene3D G3DSA:3.20.20.190 19 289 6.4E-75 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS17765 1b6effe70b80f8a73e1234c162d0ee32 161 PANTHER PTHR13947 40 148 3.4E-19 T 23-04-2016 DC74_RS17765 1b6effe70b80f8a73e1234c162d0ee32 161 SUPERFAMILY SSF55729 3 155 1.89E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS17765 1b6effe70b80f8a73e1234c162d0ee32 161 Pfam PF00583 Acetyltransferase (GNAT) family 52 135 2.7E-10 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS17765 1b6effe70b80f8a73e1234c162d0ee32 161 Gene3D G3DSA:3.40.630.30 2 157 8.2E-28 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS39395 b28498e15c3f45b6dcfa96bb2137cae6 399 PANTHER PTHR23501 1 384 1.8E-128 T 23-04-2016 DC74_RS39395 b28498e15c3f45b6dcfa96bb2137cae6 399 SUPERFAMILY SSF103473 3 385 4.97E-47 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS39395 b28498e15c3f45b6dcfa96bb2137cae6 399 Pfam PF07690 Major Facilitator Superfamily 12 228 1.6E-20 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS39395 b28498e15c3f45b6dcfa96bb2137cae6 399 Gene3D G3DSA:1.20.1250.20 3 181 6.8E-20 T 23-04-2016 DC74_RS39395 b28498e15c3f45b6dcfa96bb2137cae6 399 Gene3D G3DSA:1.20.1250.20 215 388 1.3E-10 T 23-04-2016 DC74_RS39395 b28498e15c3f45b6dcfa96bb2137cae6 399 PANTHER PTHR23501:SF79 1 384 1.8E-128 T 23-04-2016 DC74_RS31760 ba917dd1be9c499cb4cb7203f5de6cee 174 Pfam PF01575 MaoC like domain 12 125 5.3E-15 T 23-04-2016 IPR002539 MaoC-like domain DC74_RS31760 ba917dd1be9c499cb4cb7203f5de6cee 174 SUPERFAMILY SSF54637 2 148 3.73E-43 T 23-04-2016 IPR029069 HotDog domain DC74_RS31760 ba917dd1be9c499cb4cb7203f5de6cee 174 Gene3D G3DSA:3.10.129.10 2 148 2.4E-41 T 23-04-2016 IPR029069 HotDog domain DC74_RS31760 ba917dd1be9c499cb4cb7203f5de6cee 174 PANTHER PTHR13078 1 163 9.7E-63 T 23-04-2016 DC74_RS26840 154dfdd072e20930504e82aa1fb1584e 340 Gene3D G3DSA:3.30.1360.70 3 111 7.5E-26 T 23-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS26840 154dfdd072e20930504e82aa1fb1584e 340 Gene3D G3DSA:1.10.730.10 208 339 3.1E-24 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS26840 154dfdd072e20930504e82aa1fb1584e 340 SMART SM01016 4 92 1.7E-25 T 23-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS26840 154dfdd072e20930504e82aa1fb1584e 340 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 14 92 2.3E-18 T 23-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS26840 154dfdd072e20930504e82aa1fb1584e 340 PANTHER PTHR11956 149 340 1.9E-22 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS26840 154dfdd072e20930504e82aa1fb1584e 340 SUPERFAMILY SSF47323 208 339 1.96E-18 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS26840 154dfdd072e20930504e82aa1fb1584e 340 Pfam PF05746 DALR anticodon binding domain 214 339 2.4E-17 T 23-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 DC74_RS26840 154dfdd072e20930504e82aa1fb1584e 340 SUPERFAMILY SSF55190 23 112 2.49E-17 T 23-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 DC74_RS26840 154dfdd072e20930504e82aa1fb1584e 340 PANTHER PTHR11956:SF6 149 340 1.9E-22 T 23-04-2016 DC74_RS26840 154dfdd072e20930504e82aa1fb1584e 340 SMART SM00836 214 340 2.9E-23 T 23-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 DC74_RS25515 16b21070c84fe6b7ed38a12309984778 208 PANTHER PTHR35400 13 200 2.1E-38 T 23-04-2016 DC74_RS25515 16b21070c84fe6b7ed38a12309984778 208 Gene3D G3DSA:3.90.1570.10 16 163 3.1E-14 T 23-04-2016 IPR012296 Nuclease, putative, TT1808 DC74_RS25515 16b21070c84fe6b7ed38a12309984778 208 SUPERFAMILY SSF52980 22 161 2.14E-12 T 23-04-2016 IPR011335 Restriction endonuclease type II-like DC74_RS25515 16b21070c84fe6b7ed38a12309984778 208 Pfam PF05685 Putative restriction endonuclease 28 194 2.8E-24 T 23-04-2016 IPR008538 Domain of unknown function DUF820 DC74_RS25515 16b21070c84fe6b7ed38a12309984778 208 PANTHER PTHR35400:SF1 13 200 2.1E-38 T 23-04-2016 DC74_RS04495 5ece5332c0a95e9127f407fa9548917a 325 PANTHER PTHR30468:SF5 9 295 4.1E-110 T 23-04-2016 DC74_RS04495 5ece5332c0a95e9127f407fa9548917a 325 SUPERFAMILY SSF51197 8 292 8.7E-77 T 23-04-2016 DC74_RS04495 5ece5332c0a95e9127f407fa9548917a 325 Gene3D G3DSA:3.60.130.10 4 292 4.3E-84 T 23-04-2016 DC74_RS04495 5ece5332c0a95e9127f407fa9548917a 325 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 14 277 3.0E-49 T 23-04-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 DC74_RS04495 5ece5332c0a95e9127f407fa9548917a 325 PANTHER PTHR30468 9 295 4.1E-110 T 23-04-2016 DC74_RS12105 aead9d069c67f4ea58c4fb4b9e702917 285 Gene3D G3DSA:3.40.50.300 15 261 5.9E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12105 aead9d069c67f4ea58c4fb4b9e702917 285 Pfam PF00005 ABC transporter 34 193 5.0E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS12105 aead9d069c67f4ea58c4fb4b9e702917 285 PANTHER PTHR24220 139 266 1.6E-125 T 23-04-2016 DC74_RS12105 aead9d069c67f4ea58c4fb4b9e702917 285 PANTHER PTHR24220 19 123 1.6E-125 T 23-04-2016 DC74_RS12105 aead9d069c67f4ea58c4fb4b9e702917 285 PANTHER PTHR24220:SF491 139 266 1.6E-125 T 23-04-2016 DC74_RS12105 aead9d069c67f4ea58c4fb4b9e702917 285 PANTHER PTHR24220:SF491 19 123 1.6E-125 T 23-04-2016 DC74_RS12105 aead9d069c67f4ea58c4fb4b9e702917 285 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 241 263 3.2E-8 T 23-04-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal DC74_RS12105 aead9d069c67f4ea58c4fb4b9e702917 285 SUPERFAMILY SSF52540 16 263 2.09E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12105 aead9d069c67f4ea58c4fb4b9e702917 285 SMART SM00382 42 240 3.3E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS27405 b24abc762ee900587a2c00b2a0f3e3ae 184 PANTHER PTHR34135 1 161 1.6E-23 T 23-04-2016 DC74_RS27405 b24abc762ee900587a2c00b2a0f3e3ae 184 Pfam PF01183 Glycosyl hydrolases family 25 5 164 3.8E-37 T 23-04-2016 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 DC74_RS27405 b24abc762ee900587a2c00b2a0f3e3ae 184 SUPERFAMILY SSF51445 3 182 4.0E-33 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS27405 b24abc762ee900587a2c00b2a0f3e3ae 184 SMART SM00641 2 101 6.0E-18 T 23-04-2016 IPR018077 Glycoside hydrolase, family 25 subgroup DC74_RS27405 b24abc762ee900587a2c00b2a0f3e3ae 184 Gene3D G3DSA:3.20.20.80 2 182 6.1E-38 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS22830 a3e934f2987b6168b38f0fed4fefc73e 448 SMART SM00825 Beta-ketoacyl synthase 13 445 6.7E-13 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS22830 a3e934f2987b6168b38f0fed4fefc73e 448 PANTHER PTHR11712 193 443 5.4E-86 T 23-04-2016 DC74_RS22830 a3e934f2987b6168b38f0fed4fefc73e 448 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 278 6.7E-28 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS22830 a3e934f2987b6168b38f0fed4fefc73e 448 SUPERFAMILY SSF53901 246 443 7.09E-62 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22830 a3e934f2987b6168b38f0fed4fefc73e 448 Gene3D G3DSA:3.40.47.10 297 443 1.3E-48 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22830 a3e934f2987b6168b38f0fed4fefc73e 448 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 286 400 6.0E-30 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS22830 a3e934f2987b6168b38f0fed4fefc73e 448 Gene3D G3DSA:3.40.47.10 15 291 4.1E-42 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS22830 a3e934f2987b6168b38f0fed4fefc73e 448 SUPERFAMILY SSF53901 12 285 1.51E-43 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS35490 ffbe61b24caca0be69f7586010b056de 220 SUPERFAMILY SSF52540 3 214 3.31E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35490 ffbe61b24caca0be69f7586010b056de 220 SMART SM00382 25 212 6.0E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS35490 ffbe61b24caca0be69f7586010b056de 220 Gene3D G3DSA:3.40.50.300 2 214 3.3E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35490 ffbe61b24caca0be69f7586010b056de 220 PANTHER PTHR24220 2 213 2.6E-72 T 23-04-2016 DC74_RS35490 ffbe61b24caca0be69f7586010b056de 220 Pfam PF00005 ABC transporter 16 163 1.8E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 119 751 43.141 T 23-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 SUPERFAMILY SSF51445 198 640 2.11E-108 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 SUPERFAMILY SSF81296 37 132 3.29E-17 T 23-04-2016 IPR014756 Immunoglobulin E-set DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 PANTHER PTHR10357 67 750 0.0 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 Gene3D G3DSA:2.60.40.1180 647 750 3.2E-30 T 23-04-2016 IPR013780 Glycosyl hydrolase, all-beta DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 PIRSF PIRSF000463 29 751 5.6E-291 T 23-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 143 225 1.4E-21 T 23-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 Gene3D G3DSA:2.60.40.10 131 239 2.9E-37 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 Gene3D G3DSA:2.60.40.10 36 124 8.3E-13 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 SUPERFAMILY SSF51011 647 750 2.4E-28 T 23-04-2016 DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 Pfam PF00128 Alpha amylase, catalytic domain 288 356 1.1E-8 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 652 749 3.3E-18 T 23-04-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: REACT_474 DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 127 748 2.6E-296 T 23-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 SMART SM00642 268 628 5.1E-8 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 PANTHER PTHR10357:SF160 67 750 0.0 T 23-04-2016 DC74_RS27315 a0f5ca07fe34f2992b8e7039c6fa7fb9 751 Gene3D G3DSA:3.20.20.80 263 632 1.6E-88 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS40115 db6cc3281d0ef5dbd80d46e2f66dd118 258 SUPERFAMILY SSF56973 98 148 3.01E-6 T 23-04-2016 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 Pfam PF09334 tRNA synthetases class I (M) 65 167 2.8E-12 T 23-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 SUPERFAMILY SSF47323 780 963 2.06E-28 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 SUPERFAMILY SSF50677 295 521 9.94E-43 T 23-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 Gene3D G3DSA:3.40.50.620 22 171 9.2E-134 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 Gene3D G3DSA:3.40.50.620 527 701 9.2E-134 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 Gene3D G3DSA:3.40.50.620 735 764 9.2E-134 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 Gene3D G3DSA:3.40.50.620 219 295 9.2E-134 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 Gene3D G3DSA:3.90.740.10 296 526 6.9E-52 T 23-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 SUPERFAMILY SSF52374 23 172 1.99E-109 T 23-04-2016 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 SUPERFAMILY SSF52374 220 298 1.99E-109 T 23-04-2016 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 SUPERFAMILY SSF52374 518 784 1.99E-109 T 23-04-2016 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 368 505 1.7E-38 T 23-04-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 293 341 4.3E-19 T 23-04-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 Pfam PF08264 Anticodon-binding domain of tRNA 812 924 2.6E-16 T 23-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PANTHER PTHR11946 381 558 0.0 T 23-04-2016 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PANTHER PTHR11946 220 279 0.0 T 23-04-2016 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PANTHER PTHR11946 733 964 0.0 T 23-04-2016 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PANTHER PTHR11946 311 336 0.0 T 23-04-2016 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PANTHER PTHR11946 3 172 0.0 T 23-04-2016 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PANTHER PTHR11946 584 699 0.0 T 23-04-2016 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 68 78 - T 23-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 Gene3D G3DSA:1.10.730.10 765 900 1.2E-35 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PANTHER PTHR11946:SF7 381 558 0.0 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PANTHER PTHR11946:SF7 220 279 0.0 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PANTHER PTHR11946:SF7 733 964 0.0 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PANTHER PTHR11946:SF7 311 336 0.0 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PANTHER PTHR11946:SF7 3 172 0.0 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PANTHER PTHR11946:SF7 584 699 0.0 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 18 964 21.115 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PRINTS PR00985 Leucyl-tRNA synthetase signature 225 241 1.4E-51 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PRINTS PR00985 Leucyl-tRNA synthetase signature 258 271 1.4E-51 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 169 1.4E-51 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PRINTS PR00985 Leucyl-tRNA synthetase signature 652 674 1.4E-51 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PRINTS PR00985 Leucyl-tRNA synthetase signature 604 622 1.4E-51 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PRINTS PR00985 Leucyl-tRNA synthetase signature 287 306 1.4E-51 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS15120 edf3b6cb56304182dcef1a2deb969f1a 965 PRINTS PR00985 Leucyl-tRNA synthetase signature 685 695 1.4E-51 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 DC74_RS24405 2ed17fedca3881d2d314f190ad9e56ef 400 PANTHER PTHR30634 10 391 1.1E-155 T 23-04-2016 DC74_RS24405 2ed17fedca3881d2d314f190ad9e56ef 400 SMART SM00327 224 383 2.0E-4 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS24405 2ed17fedca3881d2d314f190ad9e56ef 400 PANTHER PTHR30634:SF8 10 391 1.1E-155 T 23-04-2016 DC74_RS24405 2ed17fedca3881d2d314f190ad9e56ef 400 SUPERFAMILY SSF53300 224 386 1.63E-25 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS24405 2ed17fedca3881d2d314f190ad9e56ef 400 Pfam PF05762 VWA domain containing CoxE-like protein 162 381 2.2E-61 T 23-04-2016 IPR008912 Uncharacterised protein family CoxE-like DC74_RS24405 2ed17fedca3881d2d314f190ad9e56ef 400 Gene3D G3DSA:3.40.50.410 225 343 1.3E-5 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS02035 33e4a2549126b6abfbf0d64cd8b6fc96 443 PANTHER PTHR23513 6 434 5.3E-17 T 23-04-2016 DC74_RS02035 33e4a2549126b6abfbf0d64cd8b6fc96 443 SUPERFAMILY SSF103473 23 432 2.35E-18 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS02035 33e4a2549126b6abfbf0d64cd8b6fc96 443 Pfam PF07690 Major Facilitator Superfamily 36 393 5.6E-15 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS10170 f4ff47a39519f43f8e13c7f48e357b38 236 PANTHER PTHR11922 40 213 1.1E-46 T 23-04-2016 DC74_RS10170 f4ff47a39519f43f8e13c7f48e357b38 236 Gene3D G3DSA:3.40.50.880 7 215 1.3E-41 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS10170 f4ff47a39519f43f8e13c7f48e357b38 236 SUPERFAMILY SSF52317 33 228 2.75E-38 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS10170 f4ff47a39519f43f8e13c7f48e357b38 236 PANTHER PTHR11922:SF18 40 213 1.1E-46 T 23-04-2016 DC74_RS10170 f4ff47a39519f43f8e13c7f48e357b38 236 Pfam PF07722 Peptidase C26 7 213 1.1E-64 T 23-04-2016 IPR011697 Peptidase C26 GO:0006541|GO:0016787 DC74_RS29435 004094516256ea901b01a827718a4470 70 SUPERFAMILY SSF160582 1 68 1.29E-31 T 23-04-2016 DC74_RS29435 004094516256ea901b01a827718a4470 70 PANTHER PTHR38444:SF1 1 69 1.4E-39 T 23-04-2016 DC74_RS29435 004094516256ea901b01a827718a4470 70 Pfam PF03621 MbtH-like protein 1 52 6.9E-29 T 23-04-2016 IPR005153 MbtH-like protein DC74_RS29435 004094516256ea901b01a827718a4470 70 SMART SM00923 3 53 1.3E-30 T 23-04-2016 IPR005153 MbtH-like protein DC74_RS29435 004094516256ea901b01a827718a4470 70 PANTHER PTHR38444 1 69 1.4E-39 T 23-04-2016 DC74_RS29435 004094516256ea901b01a827718a4470 70 Gene3D G3DSA:3.90.820.10 10 68 3.5E-31 T 23-04-2016 DC74_RS31915 d57e3f6ea957996584405f1b24a46d52 117 SUPERFAMILY SSF54593 9 109 4.4E-12 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS31915 d57e3f6ea957996584405f1b24a46d52 117 Gene3D G3DSA:3.10.180.10 5 109 6.2E-14 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS30015 698daba43a0789c035ed0f074771fd08 180 PANTHER PTHR22916 4 180 1.3E-33 T 23-04-2016 DC74_RS30015 698daba43a0789c035ed0f074771fd08 180 SUPERFAMILY SSF53448 2 180 2.69E-47 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS30015 698daba43a0789c035ed0f074771fd08 180 Gene3D G3DSA:3.90.550.10 4 180 2.5E-38 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS30015 698daba43a0789c035ed0f074771fd08 180 Pfam PF00535 Glycosyl transferase family 2 5 162 2.5E-33 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS04440 e751549951293a04c7eb452aa8936c8b 202 SUPERFAMILY SSF51197 2 198 1.04E-41 T 23-04-2016 DC74_RS04440 e751549951293a04c7eb452aa8936c8b 202 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 2 197 1.4E-50 T 23-04-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like DC74_RS04440 e751549951293a04c7eb452aa8936c8b 202 PANTHER PTHR16557 1 197 5.3E-51 T 23-04-2016 IPR004574 Alkylated DNA repair protein AlkB GO:0006281|GO:0055114 DC74_RS04440 e751549951293a04c7eb452aa8936c8b 202 Gene3D G3DSA:2.60.120.590 1 197 1.0E-46 T 23-04-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like DC74_RS15075 a5dd2aba0993c0d8b4aee02f7794c83f 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.861 T 23-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15075 a5dd2aba0993c0d8b4aee02f7794c83f 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 68 2.0E-7 T 23-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15075 a5dd2aba0993c0d8b4aee02f7794c83f 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 86 1.5E-24 T 23-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15075 a5dd2aba0993c0d8b4aee02f7794c83f 88 PANTHER PTHR33398 2 87 9.8E-30 T 23-04-2016 DC74_RS15075 a5dd2aba0993c0d8b4aee02f7794c83f 88 Gene3D G3DSA:1.20.58.110 2 86 1.8E-28 T 23-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15075 a5dd2aba0993c0d8b4aee02f7794c83f 88 Pfam PF01649 Ribosomal protein S20 2 83 1.5E-26 T 23-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS15075 a5dd2aba0993c0d8b4aee02f7794c83f 88 SUPERFAMILY SSF46992 3 86 1.83E-27 T 23-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS00525 a90af37986077009ba4952528da8da62 423 PANTHER PTHR23028:SF53 1 394 1.5E-91 T 23-04-2016 DC74_RS00525 a90af37986077009ba4952528da8da62 423 Pfam PF01757 Acyltransferase family 31 358 2.0E-27 T 23-04-2016 IPR002656 Acyltransferase 3 GO:0016747 DC74_RS00525 a90af37986077009ba4952528da8da62 423 PANTHER PTHR23028 1 394 1.5E-91 T 23-04-2016 DC74_RS21040 1e47914b33a286d72f9b09eb0a44a6e3 299 PANTHER PTHR10120 1 257 5.2E-89 T 23-04-2016 DC74_RS21040 1e47914b33a286d72f9b09eb0a44a6e3 299 PANTHER PTHR10120 275 297 5.2E-89 T 23-04-2016 DC74_RS21040 1e47914b33a286d72f9b09eb0a44a6e3 299 PANTHER PTHR10120:SF19 1 257 5.2E-89 T 23-04-2016 DC74_RS21040 1e47914b33a286d72f9b09eb0a44a6e3 299 PANTHER PTHR10120:SF19 275 297 5.2E-89 T 23-04-2016 DC74_RS21040 1e47914b33a286d72f9b09eb0a44a6e3 299 Gene3D G3DSA:3.30.2010.10 68 159 7.7E-33 T 23-04-2016 DC74_RS21040 1e47914b33a286d72f9b09eb0a44a6e3 299 Hamap MF_00188 Protease HtpX [htpX]. 8 292 25.532 T 23-04-2016 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 DC74_RS21040 1e47914b33a286d72f9b09eb0a44a6e3 299 Pfam PF01435 Peptidase family M48 76 290 4.9E-36 T 23-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DC74_RS27740 0e7aa76528017c44b9995145cbe50f80 346 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 337 2.0E-92 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS27740 0e7aa76528017c44b9995145cbe50f80 346 SUPERFAMILY SSF53659 4 342 1.15E-110 T 23-04-2016 DC74_RS27740 0e7aa76528017c44b9995145cbe50f80 346 PANTHER PTHR11835 1 344 7.8E-200 T 23-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 DC74_RS27740 0e7aa76528017c44b9995145cbe50f80 346 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 23-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 DC74_RS27740 0e7aa76528017c44b9995145cbe50f80 346 Gene3D G3DSA:3.40.718.10 5 339 1.6E-116 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS27740 0e7aa76528017c44b9995145cbe50f80 346 SMART SM01329 6 340 5.2E-165 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS27740 0e7aa76528017c44b9995145cbe50f80 346 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 5 344 59.427 T 23-04-2016 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 DC74_RS27740 0e7aa76528017c44b9995145cbe50f80 346 PANTHER PTHR11835:SF49 1 344 7.8E-200 T 23-04-2016 DC74_RS20555 ea7653042424be325a0db075d286c1a3 502 Gene3D G3DSA:3.60.40.10 2 237 2.8E-73 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS20555 ea7653042424be325a0db075d286c1a3 502 PANTHER PTHR13832 1 257 2.3E-86 T 23-04-2016 IPR015655 Protein phosphatase 2C family GO:0004722|GO:0006470 KEGG: 04660+3.1.3.16 DC74_RS20555 ea7653042424be325a0db075d286c1a3 502 SMART SM00331 11 237 1.1E-38 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS20555 ea7653042424be325a0db075d286c1a3 502 PANTHER PTHR13832:SF226 1 257 2.3E-86 T 23-04-2016 DC74_RS20555 ea7653042424be325a0db075d286c1a3 502 SMART SM00332 2 235 3.5E-28 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS20555 ea7653042424be325a0db075d286c1a3 502 Pfam PF00481 Protein phosphatase 2C 22 202 2.6E-10 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS20555 ea7653042424be325a0db075d286c1a3 502 SUPERFAMILY SSF81606 4 236 3.01E-66 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS13325 987faf09f90b39a4114799f035216bad 208 Gene3D G3DSA:1.10.10.60 8 56 7.6E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS13325 987faf09f90b39a4114799f035216bad 208 PANTHER PTHR30055 2 203 2.2E-22 T 23-04-2016 DC74_RS13325 987faf09f90b39a4114799f035216bad 208 Gene3D G3DSA:1.10.357.10 58 194 1.7E-26 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS13325 987faf09f90b39a4114799f035216bad 208 PANTHER PTHR30055:SF66 2 203 2.2E-22 T 23-04-2016 DC74_RS13325 987faf09f90b39a4114799f035216bad 208 Pfam PF16859 Bacterial transcriptional repressor C-terminal 80 188 2.5E-21 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS13325 987faf09f90b39a4114799f035216bad 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 63 8.2E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13325 987faf09f90b39a4114799f035216bad 208 SUPERFAMILY SSF48498 80 194 1.31E-20 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS13325 987faf09f90b39a4114799f035216bad 208 SUPERFAMILY SSF46689 9 68 5.49E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS09825 2efe702376df02d73130919fa17777bf 244 PANTHER PTHR30450:SF1 2 224 1.7E-109 T 23-04-2016 DC74_RS09825 2efe702376df02d73130919fa17777bf 244 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 216 2.9E-21 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS09825 2efe702376df02d73130919fa17777bf 244 Gene3D G3DSA:1.10.3720.10 7 215 6.9E-43 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS09825 2efe702376df02d73130919fa17777bf 244 SUPERFAMILY SSF161098 8 203 4.71E-44 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS09825 2efe702376df02d73130919fa17777bf 244 PANTHER PTHR30450 2 224 1.7E-109 T 23-04-2016 DC74_RS08105 0ddf6b54d3b1c050a9c1ca536a04f77b 178 Gene3D G3DSA:2.60.200.20 77 171 2.3E-27 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS08105 0ddf6b54d3b1c050a9c1ca536a04f77b 178 SUPERFAMILY SSF49879 52 170 4.02E-30 T 23-04-2016 IPR008984 SMAD/FHA domain GO:0005515 DC74_RS08105 0ddf6b54d3b1c050a9c1ca536a04f77b 178 SMART SM00240 98 149 1.5E-9 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS08105 0ddf6b54d3b1c050a9c1ca536a04f77b 178 PANTHER PTHR15715 52 163 7.2E-28 T 23-04-2016 DC74_RS08105 0ddf6b54d3b1c050a9c1ca536a04f77b 178 Pfam PF13240 zinc-ribbon domain 3 25 4.1E-7 T 23-04-2016 IPR026870 Zinc-ribbon domain DC74_RS08105 0ddf6b54d3b1c050a9c1ca536a04f77b 178 Pfam PF00498 FHA domain 100 163 9.2E-18 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS17390 9c2914c97dca7fe3ed183c51b38fe71f 74 Pfam PF04149 Domain of unknown function (DUF397) 15 68 2.3E-22 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS04545 e8716ffa7fab89a22bdc86fd45617ddd 135 SUPERFAMILY SSF53901 4 112 9.72E-16 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS04545 e8716ffa7fab89a22bdc86fd45617ddd 135 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 37 112 9.8E-11 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS04545 e8716ffa7fab89a22bdc86fd45617ddd 135 Gene3D G3DSA:3.40.47.10 39 112 2.5E-15 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS23415 8d9488e0e785a6bc66c4e20ebc37eedf 90 Gene3D G3DSA:1.10.10.10 11 84 4.0E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20380 dd3cb815525316e49a5bbe5befa2b995 548 PANTHER PTHR24362:SF160 18 284 8.2E-102 T 23-04-2016 DC74_RS20380 dd3cb815525316e49a5bbe5befa2b995 548 SUPERFAMILY SSF56112 18 374 7.42E-75 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS20380 dd3cb815525316e49a5bbe5befa2b995 548 Pfam PF03793 PASTA domain 483 545 1.2E-6 T 23-04-2016 IPR005543 PASTA domain DC74_RS20380 dd3cb815525316e49a5bbe5befa2b995 548 Pfam PF00069 Protein kinase domain 20 284 9.8E-49 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS20380 dd3cb815525316e49a5bbe5befa2b995 548 SMART SM00220 20 287 1.3E-62 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS20380 dd3cb815525316e49a5bbe5befa2b995 548 PANTHER PTHR24362 18 284 8.2E-102 T 23-04-2016 DC74_RS20380 dd3cb815525316e49a5bbe5befa2b995 548 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 147 159 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS20380 dd3cb815525316e49a5bbe5befa2b995 548 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 26 49 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 DC74_RS20380 dd3cb815525316e49a5bbe5befa2b995 548 Gene3D G3DSA:1.10.510.10 114 354 7.5E-50 T 23-04-2016 DC74_RS20380 dd3cb815525316e49a5bbe5befa2b995 548 Gene3D G3DSA:3.30.200.20 16 103 2.4E-24 T 23-04-2016 DC74_RS25505 03b1f12d7d6837742294954859a6abf4 184 PANTHER PTHR10681 1 184 4.5E-103 T 23-04-2016 DC74_RS25505 03b1f12d7d6837742294954859a6abf4 184 SUPERFAMILY SSF52833 2 177 1.26E-53 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS25505 03b1f12d7d6837742294954859a6abf4 184 PIRSF PIRSF000239 1 184 4.8E-50 T 23-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 DC74_RS25505 03b1f12d7d6837742294954859a6abf4 184 PANTHER PTHR10681:SF87 1 184 4.5E-103 T 23-04-2016 DC74_RS25505 03b1f12d7d6837742294954859a6abf4 184 Gene3D G3DSA:3.40.30.10 2 177 1.9E-61 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS25505 03b1f12d7d6837742294954859a6abf4 184 Pfam PF00578 AhpC/TSA family 4 136 1.1E-33 T 23-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS01415 a4c7b2fe0cf5d315b6e628a0fd6186b1 274 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 29 244 9.3E-75 T 23-04-2016 IPR030903 Cyclodileucine synthase GO:0016755 DC74_RS01415 a4c7b2fe0cf5d315b6e628a0fd6186b1 274 Pfam PF16715 Cyclodipeptide synthase 29 244 1.7E-63 T 23-04-2016 IPR030903 Cyclodileucine synthase GO:0016755 DC74_RS11130 c5c9fd859ed0dc9f3ada494caf2ace22 277 SMART SM00382 28 217 6.1E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS11130 c5c9fd859ed0dc9f3ada494caf2ace22 277 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS11130 c5c9fd859ed0dc9f3ada494caf2ace22 277 SUPERFAMILY SSF52540 4 229 5.54E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11130 c5c9fd859ed0dc9f3ada494caf2ace22 277 PANTHER PTHR24220 5 272 1.9E-157 T 23-04-2016 DC74_RS11130 c5c9fd859ed0dc9f3ada494caf2ace22 277 Pfam PF00005 ABC transporter 20 167 1.6E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS11130 c5c9fd859ed0dc9f3ada494caf2ace22 277 PANTHER PTHR24220:SF438 5 272 1.9E-157 T 23-04-2016 DC74_RS11130 c5c9fd859ed0dc9f3ada494caf2ace22 277 Gene3D G3DSA:3.40.50.300 4 233 1.0E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15940 6ee5434cc57c9dbf2f150d6db6820886 173 PRINTS PR01438 Universal stress protein signature 151 173 1.7E-6 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS15940 6ee5434cc57c9dbf2f150d6db6820886 173 PRINTS PR01438 Universal stress protein signature 37 55 1.7E-6 T 23-04-2016 IPR006015 Universal stress protein A DC74_RS15940 6ee5434cc57c9dbf2f150d6db6820886 173 PANTHER PTHR31964 40 173 9.8E-16 T 23-04-2016 DC74_RS15940 6ee5434cc57c9dbf2f150d6db6820886 173 Pfam PF00582 Universal stress protein family 40 173 4.8E-24 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS15940 6ee5434cc57c9dbf2f150d6db6820886 173 Gene3D G3DSA:3.40.50.620 39 173 9.4E-34 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS15940 6ee5434cc57c9dbf2f150d6db6820886 173 SUPERFAMILY SSF52402 40 173 5.36E-23 T 23-04-2016 DC74_RS29090 ca5e637a93c6b6a4116bf73c6e5808dd 396 PANTHER PTHR10151:SF70 59 282 2.1E-24 T 23-04-2016 DC74_RS29090 ca5e637a93c6b6a4116bf73c6e5808dd 396 SUPERFAMILY SSF53649 53 392 5.4E-59 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS29090 ca5e637a93c6b6a4116bf73c6e5808dd 396 Gene3D G3DSA:3.40.720.10 49 328 1.9E-43 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 DC74_RS29090 ca5e637a93c6b6a4116bf73c6e5808dd 396 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 58 381 1.2E-41 T 23-04-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 DC74_RS29090 ca5e637a93c6b6a4116bf73c6e5808dd 396 PANTHER PTHR10151 59 282 2.1E-24 T 23-04-2016 IPR024873 Ectonucleotide pyrophosphatase/phosphodiesterase family DC74_RS06590 112cbc543fc4861ed814639bd99e5256 508 Gene3D G3DSA:3.50.50.60 16 209 3.9E-23 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06590 112cbc543fc4861ed814639bd99e5256 508 Gene3D G3DSA:3.50.50.60 319 362 3.9E-23 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06590 112cbc543fc4861ed814639bd99e5256 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 342 358 4.9E-9 T 23-04-2016 DC74_RS06590 112cbc543fc4861ed814639bd99e5256 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 181 196 4.9E-9 T 23-04-2016 DC74_RS06590 112cbc543fc4861ed814639bd99e5256 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 327 342 4.9E-9 T 23-04-2016 DC74_RS06590 112cbc543fc4861ed814639bd99e5256 508 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 17 39 4.9E-9 T 23-04-2016 DC74_RS06590 112cbc543fc4861ed814639bd99e5256 508 SUPERFAMILY SSF51905 324 377 3.67E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06590 112cbc543fc4861ed814639bd99e5256 508 SUPERFAMILY SSF51905 17 211 3.67E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06590 112cbc543fc4861ed814639bd99e5256 508 PANTHER PTHR10617 18 364 1.7E-26 T 23-04-2016 DC74_RS06590 112cbc543fc4861ed814639bd99e5256 508 PANTHER PTHR10617:SF114 18 364 1.7E-26 T 23-04-2016 DC74_RS08830 bc74760801ea6f884df1f5608ed93804 409 PANTHER PTHR23514 12 399 5.3E-120 T 23-04-2016 DC74_RS08830 bc74760801ea6f884df1f5608ed93804 409 Gene3D G3DSA:1.20.1250.20 224 395 2.3E-13 T 23-04-2016 DC74_RS08830 bc74760801ea6f884df1f5608ed93804 409 SUPERFAMILY SSF103473 8 396 3.92E-37 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS08830 bc74760801ea6f884df1f5608ed93804 409 PANTHER PTHR23514:SF13 12 399 5.3E-120 T 23-04-2016 DC74_RS08830 bc74760801ea6f884df1f5608ed93804 409 Gene3D G3DSA:1.20.1250.20 16 198 9.4E-15 T 23-04-2016 DC74_RS08830 bc74760801ea6f884df1f5608ed93804 409 Pfam PF07690 Major Facilitator Superfamily 33 204 5.3E-11 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS13320 95a453373591ef93cea468ba353c5557 339 Gene3D G3DSA:3.60.10.10 121 278 3.1E-6 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS13320 95a453373591ef93cea468ba353c5557 339 SUPERFAMILY SSF56219 122 338 4.71E-26 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS13320 95a453373591ef93cea468ba353c5557 339 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 127 330 3.0E-17 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS07595 3793a15cc5583cfbc30215939f1dd6a9 131 Pfam PF11236 Protein of unknown function (DUF3037) 13 130 5.0E-40 T 23-04-2016 IPR021398 Protein of unknown function DUF3037 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 PRINTS PR00359 B-class P450 signature 268 279 9.5E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 PRINTS PR00359 B-class P450 signature 187 209 9.5E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 PRINTS PR00359 B-class P450 signature 88 99 9.5E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 PRINTS PR00359 B-class P450 signature 344 355 9.5E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 PRINTS PR00359 B-class P450 signature 286 313 9.5E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 PRINTS PR00359 B-class P450 signature 151 166 9.5E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 PRINTS PR00359 B-class P450 signature 314 329 9.5E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 PRINTS PR00359 B-class P450 signature 335 344 9.5E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 PRINTS PR00359 B-class P450 signature 134 150 9.5E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 Gene3D G3DSA:1.10.630.10 8 394 4.0E-124 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 SUPERFAMILY SSF48264 10 394 1.23E-96 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 Pfam PF00067 Cytochrome P450 176 367 2.9E-28 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS14545 3661624072a1e6b518536bc203acf47c 396 PANTHER PTHR11712 1 394 3.8E-84 T 23-04-2016 DC74_RS05250 f65bd27e6e7fe0fad1316431d0e5ca79 426 PANTHER PTHR23517 7 415 3.3E-68 T 23-04-2016 DC74_RS05250 f65bd27e6e7fe0fad1316431d0e5ca79 426 Pfam PF07690 Major Facilitator Superfamily 24 358 1.9E-30 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS05250 f65bd27e6e7fe0fad1316431d0e5ca79 426 SUPERFAMILY SSF103473 12 391 7.06E-43 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05250 f65bd27e6e7fe0fad1316431d0e5ca79 426 PANTHER PTHR23517:SF2 7 415 3.3E-68 T 23-04-2016 DC74_RS05250 f65bd27e6e7fe0fad1316431d0e5ca79 426 Gene3D G3DSA:1.20.1250.20 14 188 1.0E-25 T 23-04-2016 DC74_RS05250 f65bd27e6e7fe0fad1316431d0e5ca79 426 Gene3D G3DSA:1.20.1250.20 204 389 4.4E-9 T 23-04-2016 DC74_RS30450 c428e570562ec26e938a26a58964b233 380 SUPERFAMILY SSF52540 119 267 3.74E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30450 c428e570562ec26e938a26a58964b233 380 Pfam PF07728 AAA domain (dynein-related subfamily) 129 259 1.0E-17 T 23-04-2016 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 DC74_RS30450 c428e570562ec26e938a26a58964b233 380 SMART SM00382 126 270 0.0022 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS30450 c428e570562ec26e938a26a58964b233 380 Gene3D G3DSA:3.40.50.300 121 266 7.1E-25 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30450 c428e570562ec26e938a26a58964b233 380 PANTHER PTHR22908 129 317 3.0E-37 T 23-04-2016 DC74_RS32700 fd6f19642110eff07dc0f5cb4808b593 421 Pfam PF13535 ATP-grasp domain 151 296 5.4E-16 T 23-04-2016 DC74_RS32700 fd6f19642110eff07dc0f5cb4808b593 421 SMART SM01209 116 294 4.9E-4 T 23-04-2016 DC74_RS32700 fd6f19642110eff07dc0f5cb4808b593 421 SUPERFAMILY SSF56059 97 333 1.04E-33 T 23-04-2016 DC74_RS32700 fd6f19642110eff07dc0f5cb4808b593 421 PANTHER PTHR23132 112 368 1.6E-17 T 23-04-2016 DC74_RS32700 fd6f19642110eff07dc0f5cb4808b593 421 Gene3D G3DSA:3.30.470.20 109 326 5.6E-24 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS01305 507d460416155a7c0acea4cbfd345404 237 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 3 237 3.5E-56 T 23-04-2016 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 DC74_RS01305 507d460416155a7c0acea4cbfd345404 237 PANTHER PTHR36852 4 237 1.2E-36 T 23-04-2016 DC74_RS15890 49f964daa9573d188d3d6806122b4353 296 Pfam PF13622 Thioesterase-like superfamily 33 290 2.1E-62 T 23-04-2016 DC74_RS15890 49f964daa9573d188d3d6806122b4353 296 Gene3D G3DSA:3.10.129.10 126 292 2.1E-49 T 23-04-2016 IPR029069 HotDog domain DC74_RS15890 49f964daa9573d188d3d6806122b4353 296 Gene3D G3DSA:3.10.129.10 3 111 2.2E-48 T 23-04-2016 IPR029069 HotDog domain DC74_RS15890 49f964daa9573d188d3d6806122b4353 296 PANTHER PTHR11066:SF34 2 296 1.0E-110 T 23-04-2016 DC74_RS15890 49f964daa9573d188d3d6806122b4353 296 SUPERFAMILY SSF54637 5 113 1.17E-42 T 23-04-2016 IPR029069 HotDog domain DC74_RS15890 49f964daa9573d188d3d6806122b4353 296 PANTHER PTHR11066 2 296 1.0E-110 T 23-04-2016 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 DC74_RS15890 49f964daa9573d188d3d6806122b4353 296 SUPERFAMILY SSF54637 117 293 4.27E-47 T 23-04-2016 IPR029069 HotDog domain DC74_RS31420 fa19b8d9da5a6f14ac8eeca0ddcb56b6 268 PANTHER PTHR28047 1 231 3.0E-68 T 23-04-2016 DC74_RS31420 fa19b8d9da5a6f14ac8eeca0ddcb56b6 268 PANTHER PTHR28047:SF1 1 231 3.0E-68 T 23-04-2016 DC74_RS03980 1aaf84494c5f0b4bae742a3ffa26963c 290 PANTHER PTHR10587:SF72 13 280 7.6E-28 T 23-04-2016 DC74_RS03980 1aaf84494c5f0b4bae742a3ffa26963c 290 SUPERFAMILY SSF88713 4 283 2.67E-58 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS03980 1aaf84494c5f0b4bae742a3ffa26963c 290 Pfam PF01522 Polysaccharide deacetylase 63 174 8.5E-8 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS03980 1aaf84494c5f0b4bae742a3ffa26963c 290 PANTHER PTHR10587 13 280 7.6E-28 T 23-04-2016 DC74_RS03980 1aaf84494c5f0b4bae742a3ffa26963c 290 Gene3D G3DSA:3.20.20.370 4 284 1.3E-62 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS22310 a30022f358fb94c3c4182d5025bc3441 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.816 T 23-04-2016 IPR023036 Ribosomal protein S14, bacterial/plastid DC74_RS22310 a30022f358fb94c3c4182d5025bc3441 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 3.1E-21 T 23-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS22310 a30022f358fb94c3c4182d5025bc3441 101 SUPERFAMILY SSF57716 2 101 6.65E-33 T 23-04-2016 DC74_RS22310 a30022f358fb94c3c4182d5025bc3441 101 Gene3D G3DSA:4.10.830.10 42 101 4.0E-25 T 23-04-2016 DC74_RS22310 a30022f358fb94c3c4182d5025bc3441 101 PANTHER PTHR19836:SF21 1 101 4.5E-59 T 23-04-2016 DC74_RS22310 a30022f358fb94c3c4182d5025bc3441 101 PANTHER PTHR19836 1 101 4.5E-59 T 23-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 Gene3D G3DSA:3.30.540.10 16 165 3.6E-48 T 23-04-2016 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 PANTHER PTHR20854:SF4 11 237 5.7E-81 T 23-04-2016 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 223 237 - T 23-04-2016 IPR020550 Inositol monophosphatase, conserved site GO:0046854 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 Gene3D G3DSA:3.40.190.80 166 268 3.4E-30 T 23-04-2016 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 94 107 - T 23-04-2016 IPR020583 Inositol monophosphatase, metal-binding site DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 Pfam PF00459 Inositol monophosphatase family 16 237 3.8E-57 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 52 72 1.6E-40 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 189 210 1.6E-40 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 220 244 1.6E-40 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 74 90 1.6E-40 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 94 110 1.6E-40 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 143 166 1.6E-40 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 PANTHER PTHR20854 11 237 5.7E-81 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 PRINTS PR01959 SuhB family inositol monophosphatase signature 117 136 1.8E-6 T 23-04-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 PRINTS PR01959 SuhB family inositol monophosphatase signature 210 222 1.8E-6 T 23-04-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 DC74_RS29135 1077f600f2a9380c7d4f3ebc2abe5c7e 275 SUPERFAMILY SSF56655 16 268 5.24E-75 T 23-04-2016 DC74_RS15385 dec6f7f96c2cbcf67b89aef89882f166 199 Pfam PF02632 BioY family 54 193 3.0E-33 T 23-04-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 DC74_RS15385 dec6f7f96c2cbcf67b89aef89882f166 199 PIRSF PIRSF016661 18 198 7.6E-38 T 23-04-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 DC74_RS15385 dec6f7f96c2cbcf67b89aef89882f166 199 PANTHER PTHR34295 27 194 2.1E-60 T 23-04-2016 DC74_RS15385 dec6f7f96c2cbcf67b89aef89882f166 199 PANTHER PTHR34295:SF1 27 194 2.1E-60 T 23-04-2016 DC74_RS31805 8233f29021035ee92fb47666cb863581 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.8E-6 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS31805 8233f29021035ee92fb47666cb863581 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.8E-6 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS31805 8233f29021035ee92fb47666cb863581 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.8E-6 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS31805 8233f29021035ee92fb47666cb863581 122 Pfam PF13411 MerR HTH family regulatory protein 2 62 5.2E-17 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS31805 8233f29021035ee92fb47666cb863581 122 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS31805 8233f29021035ee92fb47666cb863581 122 Gene3D G3DSA:1.10.1660.10 2 113 1.5E-27 T 23-04-2016 DC74_RS31805 8233f29021035ee92fb47666cb863581 122 PANTHER PTHR30204:SF4 2 113 4.4E-23 T 23-04-2016 DC74_RS31805 8233f29021035ee92fb47666cb863581 122 PANTHER PTHR30204 2 113 4.4E-23 T 23-04-2016 DC74_RS31805 8233f29021035ee92fb47666cb863581 122 SMART SM00422 1 69 1.1E-17 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS31805 8233f29021035ee92fb47666cb863581 122 SUPERFAMILY SSF46955 2 113 5.49E-25 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS10815 b56cdbeadc95f763c5eae961d4a57cad 430 PANTHER PTHR11785 17 383 2.5E-57 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS10815 b56cdbeadc95f763c5eae961d4a57cad 430 PIRSF PIRSF006060 9 424 1.9E-51 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS10815 b56cdbeadc95f763c5eae961d4a57cad 430 Pfam PF13520 Amino acid permease 23 409 5.2E-39 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS17165 d31a56d34ce4a6e49e5d48eddf7feacc 226 PANTHER PTHR26402 2 225 5.4E-90 T 23-04-2016 DC74_RS17165 d31a56d34ce4a6e49e5d48eddf7feacc 226 SMART SM00862 147 223 4.4E-29 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS17165 d31a56d34ce4a6e49e5d48eddf7feacc 226 Gene3D G3DSA:1.10.10.10 130 225 2.8E-35 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17165 d31a56d34ce4a6e49e5d48eddf7feacc 226 SMART SM00448 2 113 4.2E-42 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS17165 d31a56d34ce4a6e49e5d48eddf7feacc 226 PANTHER PTHR26402:SF50 2 225 5.4E-90 T 23-04-2016 DC74_RS17165 d31a56d34ce4a6e49e5d48eddf7feacc 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 3.7E-28 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS17165 d31a56d34ce4a6e49e5d48eddf7feacc 226 Gene3D G3DSA:3.40.50.2300 2 122 2.5E-40 T 23-04-2016 DC74_RS17165 d31a56d34ce4a6e49e5d48eddf7feacc 226 SUPERFAMILY SSF52172 1 126 3.27E-41 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS17165 d31a56d34ce4a6e49e5d48eddf7feacc 226 Pfam PF00072 Response regulator receiver domain 4 114 7.8E-28 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS17165 d31a56d34ce4a6e49e5d48eddf7feacc 226 SUPERFAMILY SSF46894 129 224 6.52E-30 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS34595 9fd2abf6ac12161586ab3ea2e1b1f88a 416 Gene3D G3DSA:1.20.1250.20 212 394 4.3E-13 T 23-04-2016 DC74_RS34595 9fd2abf6ac12161586ab3ea2e1b1f88a 416 Gene3D G3DSA:1.20.1250.20 16 193 1.3E-26 T 23-04-2016 DC74_RS34595 9fd2abf6ac12161586ab3ea2e1b1f88a 416 PANTHER PTHR23518:SF2 6 386 9.0E-67 T 23-04-2016 DC74_RS34595 9fd2abf6ac12161586ab3ea2e1b1f88a 416 Pfam PF07690 Major Facilitator Superfamily 20 362 2.2E-30 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS34595 9fd2abf6ac12161586ab3ea2e1b1f88a 416 PANTHER PTHR23518 6 386 9.0E-67 T 23-04-2016 DC74_RS34595 9fd2abf6ac12161586ab3ea2e1b1f88a 416 SUPERFAMILY SSF103473 14 397 8.37E-47 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS24735 43a61d266d484f768dbffc67f0691a37 167 PANTHER PTHR34846:SF2 46 162 3.8E-12 T 23-04-2016 DC74_RS24735 43a61d266d484f768dbffc67f0691a37 167 Gene3D G3DSA:1.20.1290.10 23 165 1.5E-51 T 23-04-2016 IPR029032 AhpD-like DC74_RS24735 43a61d266d484f768dbffc67f0691a37 167 SUPERFAMILY SSF69118 24 165 1.44E-42 T 23-04-2016 IPR029032 AhpD-like DC74_RS24735 43a61d266d484f768dbffc67f0691a37 167 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 48 96 1.6E-20 T 23-04-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS24735 43a61d266d484f768dbffc67f0691a37 167 PANTHER PTHR34846 46 162 3.8E-12 T 23-04-2016 DC74_RS24735 43a61d266d484f768dbffc67f0691a37 167 Pfam PF02627 Carboxymuconolactone decarboxylase family 32 113 7.3E-20 T 23-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS30215 80c764dff87dc7801440af4220150bd9 161 Pfam PF03780 Asp23 family, cell envelope-related function 36 145 2.6E-30 T 23-04-2016 IPR005531 Alkaline shock protein Asp23 DC74_RS30215 80c764dff87dc7801440af4220150bd9 161 PANTHER PTHR34297 14 157 1.4E-43 T 23-04-2016 DC74_RS30215 80c764dff87dc7801440af4220150bd9 161 PANTHER PTHR34297:SF1 14 157 1.4E-43 T 23-04-2016 DC74_RS29375 9f93e0bc6f5530392a81ebc85a20bbcc 343 PANTHER PTHR11695 32 342 4.5E-58 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS29375 9f93e0bc6f5530392a81ebc85a20bbcc 343 SUPERFAMILY SSF51735 131 308 3.4E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29375 9f93e0bc6f5530392a81ebc85a20bbcc 343 Gene3D G3DSA:3.40.50.720 148 310 2.7E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29375 9f93e0bc6f5530392a81ebc85a20bbcc 343 Pfam PF00107 Zinc-binding dehydrogenase 164 292 1.1E-18 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS29375 9f93e0bc6f5530392a81ebc85a20bbcc 343 Gene3D G3DSA:3.90.180.10 14 147 1.9E-28 T 23-04-2016 IPR011032 GroES-like DC74_RS29375 9f93e0bc6f5530392a81ebc85a20bbcc 343 SMART SM00829 29 341 1.2E-7 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS29375 9f93e0bc6f5530392a81ebc85a20bbcc 343 SUPERFAMILY SSF50129 27 127 1.34E-22 T 23-04-2016 IPR011032 GroES-like DC74_RS29375 9f93e0bc6f5530392a81ebc85a20bbcc 343 Pfam PF16884 N-terminal domain of oxidoreductase 17 119 2.4E-22 T 23-04-2016 DC74_RS02770 e64d48d8f3506d8a92b480b20c1fa8f4 87 Pfam PF00708 Acylphosphatase 1 81 3.2E-23 T 23-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DC74_RS02770 e64d48d8f3506d8a92b480b20c1fa8f4 87 PANTHER PTHR10029 1 82 2.4E-30 T 23-04-2016 DC74_RS02770 e64d48d8f3506d8a92b480b20c1fa8f4 87 ProSitePatterns PS00151 Acylphosphatase signature 2. 26 42 - T 23-04-2016 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DC74_RS02770 e64d48d8f3506d8a92b480b20c1fa8f4 87 SUPERFAMILY SSF54975 1 82 2.09E-26 T 23-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DC74_RS02770 e64d48d8f3506d8a92b480b20c1fa8f4 87 Gene3D G3DSA:3.30.70.100 1 82 1.1E-27 T 23-04-2016 DC74_RS02770 e64d48d8f3506d8a92b480b20c1fa8f4 87 ProSitePatterns PS00150 Acylphosphatase signature 1. 2 12 - T 23-04-2016 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DC74_RS21695 7bbd9f7f50369d4b225e189d32b6986b 351 Pfam PF00107 Zinc-binding dehydrogenase 190 312 1.5E-18 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS21695 7bbd9f7f50369d4b225e189d32b6986b 351 SUPERFAMILY SSF51735 153 316 1.54E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS21695 7bbd9f7f50369d4b225e189d32b6986b 351 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 65 79 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS21695 7bbd9f7f50369d4b225e189d32b6986b 351 PANTHER PTHR11695:SF587 18 351 8.0E-191 T 23-04-2016 DC74_RS21695 7bbd9f7f50369d4b225e189d32b6986b 351 SUPERFAMILY SSF50129 9 176 3.96E-51 T 23-04-2016 IPR011032 GroES-like DC74_RS21695 7bbd9f7f50369d4b225e189d32b6986b 351 SMART SM00829 16 346 9.4E-6 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS21695 7bbd9f7f50369d4b225e189d32b6986b 351 PANTHER PTHR11695 18 351 8.0E-191 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS21695 7bbd9f7f50369d4b225e189d32b6986b 351 Gene3D G3DSA:3.40.50.720 186 296 6.4E-19 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS21695 7bbd9f7f50369d4b225e189d32b6986b 351 Gene3D G3DSA:3.90.180.10 5 185 1.5E-64 T 23-04-2016 IPR011032 GroES-like DC74_RS21695 7bbd9f7f50369d4b225e189d32b6986b 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 147 2.4E-27 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 Pfam PF01494 FAD binding domain 13 358 1.7E-77 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 3.4E-45 T 23-04-2016 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 343 3.4E-45 T 23-04-2016 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 343 359 3.4E-45 T 23-04-2016 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 3.4E-45 T 23-04-2016 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 3.4E-45 T 23-04-2016 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 171 186 3.4E-45 T 23-04-2016 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 Gene3D G3DSA:3.50.50.60 115 197 3.6E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 Gene3D G3DSA:3.50.50.60 12 78 3.6E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 Gene3D G3DSA:3.50.50.60 280 364 3.6E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 PANTHER PTHR13789:SF90 11 404 2.3E-91 T 23-04-2016 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 PANTHER PTHR13789 11 404 2.3E-91 T 23-04-2016 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 SUPERFAMILY SSF51905 279 370 5.26E-61 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08980 9a9071ffc8a4a2967d68cff576ca9c81 523 SUPERFAMILY SSF51905 12 192 5.26E-61 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS40145 344d04c30426ed765f529de4600e488a 386 Gene3D G3DSA:3.40.640.10 45 252 2.2E-43 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS40145 344d04c30426ed765f529de4600e488a 386 PANTHER PTHR30244 47 382 3.8E-47 T 23-04-2016 DC74_RS40145 344d04c30426ed765f529de4600e488a 386 Gene3D G3DSA:3.90.1150.10 262 377 4.1E-5 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS40145 344d04c30426ed765f529de4600e488a 386 PANTHER PTHR30244:SF13 47 382 3.8E-47 T 23-04-2016 DC74_RS40145 344d04c30426ed765f529de4600e488a 386 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 23 375 1.0E-62 T 23-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase DC74_RS40145 344d04c30426ed765f529de4600e488a 386 SUPERFAMILY SSF53383 44 376 3.4E-55 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS40145 344d04c30426ed765f529de4600e488a 386 PIRSF PIRSF000390 17 382 2.7E-61 T 23-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase DC74_RS21755 28158bed09949e2f34aaf12c52c24306 123 Pfam PF07179 SseB protein N-terminal domain 4 92 1.7E-5 T 23-04-2016 IPR009839 SseB protein N-terminal domain DC74_RS14895 7ae4ee9e3c62a45a6fcc87e5c8a85767 142 Gene3D G3DSA:3.30.450.30 14 128 1.0E-17 T 23-04-2016 DC74_RS14895 7ae4ee9e3c62a45a6fcc87e5c8a85767 142 PANTHER PTHR36222 2 136 7.7E-26 T 23-04-2016 DC74_RS14895 7ae4ee9e3c62a45a6fcc87e5c8a85767 142 SMART SM00960 14 106 4.7E-17 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS14895 7ae4ee9e3c62a45a6fcc87e5c8a85767 142 Pfam PF03259 Roadblock/LC7 domain 16 105 1.5E-16 T 23-04-2016 IPR004942 Roadblock/LAMTOR2 domain DC74_RS14895 7ae4ee9e3c62a45a6fcc87e5c8a85767 142 SUPERFAMILY SSF103196 11 128 2.38E-23 T 23-04-2016 DC74_RS15450 e0e5eeb6494ab5f632d7eab91ce7bc74 324 Pfam PF03405 Fatty acid desaturase 21 316 1.2E-75 T 23-04-2016 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 UniPathway: UPA00199 DC74_RS15450 e0e5eeb6494ab5f632d7eab91ce7bc74 324 PANTHER PTHR31155 21 319 5.3E-173 T 23-04-2016 DC74_RS15450 e0e5eeb6494ab5f632d7eab91ce7bc74 324 SUPERFAMILY SSF47240 16 317 3.57E-83 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS15450 e0e5eeb6494ab5f632d7eab91ce7bc74 324 PANTHER PTHR31155:SF5 21 319 5.3E-173 T 23-04-2016 DC74_RS15450 e0e5eeb6494ab5f632d7eab91ce7bc74 324 Gene3D G3DSA:1.10.620.20 15 315 3.1E-109 T 23-04-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 DC74_RS15450 e0e5eeb6494ab5f632d7eab91ce7bc74 324 PIRSF PIRSF000346 5 323 4.4E-108 T 23-04-2016 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 UniPathway: UPA00199 DC74_RS20355 ac8b7ed38081ac894699838dd97c1789 405 SUPERFAMILY SSF52518 53 391 1.21E-100 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS20355 ac8b7ed38081ac894699838dd97c1789 405 Pfam PF00676 Dehydrogenase E1 component 79 348 8.5E-81 T 23-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 DC74_RS20355 ac8b7ed38081ac894699838dd97c1789 405 PANTHER PTHR11516 41 403 7.3E-129 T 23-04-2016 DC74_RS20355 ac8b7ed38081ac894699838dd97c1789 405 Gene3D G3DSA:3.40.50.970 16 387 2.3E-134 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS20355 ac8b7ed38081ac894699838dd97c1789 405 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 49 387 7.6E-139 T 23-04-2016 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 DC74_RS01070 b0ac2be1679bf24bcb342dbdb9ba5278 534 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 13 521 1.2E-130 T 23-04-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 DC74_RS01070 b0ac2be1679bf24bcb342dbdb9ba5278 534 PANTHER PTHR30003 1 533 2.3E-183 T 23-04-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 DC74_RS01070 b0ac2be1679bf24bcb342dbdb9ba5278 534 PANTHER PTHR30003:SF0 1 533 2.3E-183 T 23-04-2016 DC74_RS01070 b0ac2be1679bf24bcb342dbdb9ba5278 534 Pfam PF02652 L-lactate permease 14 519 1.3E-130 T 23-04-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 DC74_RS39565 e8713daafb778340e57e246cf70abad8 323 Gene3D G3DSA:3.90.1200.10 104 270 4.7E-32 T 23-04-2016 DC74_RS39565 e8713daafb778340e57e246cf70abad8 323 PANTHER PTHR21310 1 271 1.7E-32 T 23-04-2016 DC74_RS39565 e8713daafb778340e57e246cf70abad8 323 PANTHER PTHR21310:SF14 1 271 1.7E-32 T 23-04-2016 DC74_RS39565 e8713daafb778340e57e246cf70abad8 323 SUPERFAMILY SSF56112 36 270 1.08E-41 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS39565 e8713daafb778340e57e246cf70abad8 323 Pfam PF01636 Phosphotransferase enzyme family 36 270 1.2E-30 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS07610 b21f13aae898a08d63cdc333381c5a53 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 9.6E-4 T 23-04-2016 DC74_RS07610 b21f13aae898a08d63cdc333381c5a53 251 Gene3D G3DSA:3.40.50.720 6 250 9.0E-74 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07610 b21f13aae898a08d63cdc333381c5a53 251 SUPERFAMILY SSF51735 6 250 5.46E-74 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07610 b21f13aae898a08d63cdc333381c5a53 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 6.0E-56 T 23-04-2016 DC74_RS07610 b21f13aae898a08d63cdc333381c5a53 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.51062E-30 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07610 b21f13aae898a08d63cdc333381c5a53 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.51062E-30 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07610 b21f13aae898a08d63cdc333381c5a53 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.51062E-30 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07610 b21f13aae898a08d63cdc333381c5a53 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.51062E-30 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07610 b21f13aae898a08d63cdc333381c5a53 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.51062E-30 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07610 b21f13aae898a08d63cdc333381c5a53 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.51062E-30 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07610 b21f13aae898a08d63cdc333381c5a53 251 PANTHER PTHR24322 157 189 3.1E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07610 b21f13aae898a08d63cdc333381c5a53 251 PANTHER PTHR24322 11 141 3.1E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS14980 5233b92868539b48a99fc79adb0703e0 209 PANTHER PTHR11935 23 198 8.0E-94 T 23-04-2016 DC74_RS14980 5233b92868539b48a99fc79adb0703e0 209 Pfam PF00753 Metallo-beta-lactamase superfamily 25 188 7.7E-24 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS14980 5233b92868539b48a99fc79adb0703e0 209 PANTHER PTHR11935:SF82 23 198 8.0E-94 T 23-04-2016 DC74_RS14980 5233b92868539b48a99fc79adb0703e0 209 Gene3D G3DSA:3.60.15.10 24 193 5.1E-47 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS14980 5233b92868539b48a99fc79adb0703e0 209 SMART SM00849 24 188 3.6E-39 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS14980 5233b92868539b48a99fc79adb0703e0 209 SUPERFAMILY SSF56281 10 200 9.3E-47 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS03035 35753c50d561084195824a75696caca8 187 Gene3D G3DSA:3.40.50.850 2 186 1.3E-53 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS03035 35753c50d561084195824a75696caca8 187 PANTHER PTHR11080 3 186 1.9E-35 T 23-04-2016 DC74_RS03035 35753c50d561084195824a75696caca8 187 Pfam PF00857 Isochorismatase family 4 179 3.7E-38 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS03035 35753c50d561084195824a75696caca8 187 SUPERFAMILY SSF52499 2 184 1.7E-51 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS00320 eba1d91cd5558d1b7a6edbb93a98d8c3 181 Gene3D G3DSA:1.10.10.10 48 173 9.9E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00320 eba1d91cd5558d1b7a6edbb93a98d8c3 181 Gene3D G3DSA:3.40.1280.10 2 35 3.8E-10 T 23-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DC74_RS00320 eba1d91cd5558d1b7a6edbb93a98d8c3 181 Pfam PF00588 SpoU rRNA Methylase family 2 30 2.8E-6 T 23-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 DC74_RS00320 eba1d91cd5558d1b7a6edbb93a98d8c3 181 SUPERFAMILY SSF46785 48 173 2.53E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00320 eba1d91cd5558d1b7a6edbb93a98d8c3 181 SUPERFAMILY SSF75217 2 37 1.31E-9 T 23-04-2016 IPR029028 Alpha/beta knot methyltransferases DC74_RS37025 18a018c0bbdb57fbc74de6dac63c38d5 639 PANTHER PTHR31563 1 618 5.9E-125 T 23-04-2016 DC74_RS37025 18a018c0bbdb57fbc74de6dac63c38d5 639 SUPERFAMILY SSF51735 378 521 5.51E-7 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37025 18a018c0bbdb57fbc74de6dac63c38d5 639 Pfam PF06241 Castor and Pollux, part of voltage-gated ion channel 260 353 2.3E-21 T 23-04-2016 IPR010420 CASTOR/POLLUX/SYM8 ion channels DC74_RS37025 18a018c0bbdb57fbc74de6dac63c38d5 639 Gene3D G3DSA:3.40.50.720 375 509 7.7E-13 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37025 18a018c0bbdb57fbc74de6dac63c38d5 639 Gene3D G3DSA:3.40.50.720 111 252 9.0E-15 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06365 ef9320143eaa2b4f3e4cc9813ee3a9da 202 PANTHER PTHR13355 101 192 2.8E-15 T 23-04-2016 DC74_RS06365 ef9320143eaa2b4f3e4cc9813ee3a9da 202 PANTHER PTHR13355:SF5 101 192 2.8E-15 T 23-04-2016 DC74_RS06365 ef9320143eaa2b4f3e4cc9813ee3a9da 202 Pfam PF00583 Acetyltransferase (GNAT) family 88 153 1.3E-6 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS06365 ef9320143eaa2b4f3e4cc9813ee3a9da 202 SUPERFAMILY SSF55729 2 174 2.44E-19 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06365 ef9320143eaa2b4f3e4cc9813ee3a9da 202 Gene3D G3DSA:3.40.630.30 6 175 9.8E-16 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS24695 46a5072530c6caee713a7ba86d29b521 423 SUPERFAMILY SSF56601 79 340 1.13E-44 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS24695 46a5072530c6caee713a7ba86d29b521 423 SUPERFAMILY SSF56601 27 35 1.13E-44 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS24695 46a5072530c6caee713a7ba86d29b521 423 PANTHER PTHR21581 85 362 1.5E-64 T 23-04-2016 DC74_RS24695 46a5072530c6caee713a7ba86d29b521 423 PANTHER PTHR21581:SF1 85 362 1.5E-64 T 23-04-2016 DC74_RS24695 46a5072530c6caee713a7ba86d29b521 423 Gene3D G3DSA:3.40.710.10 86 341 1.5E-68 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS24695 46a5072530c6caee713a7ba86d29b521 423 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 86 320 1.1E-33 T 23-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 DC74_RS09345 e8146e62288170284853c3a2c7ce270f 226 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 198 1.1E-78 T 23-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 DC74_RS09345 e8146e62288170284853c3a2c7ce270f 226 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 211 1.6E-82 T 23-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 DC74_RS09345 e8146e62288170284853c3a2c7ce270f 226 SUPERFAMILY SSF51366 2 213 3.53E-66 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 DC74_RS09345 e8146e62288170284853c3a2c7ce270f 226 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 131 153 - T 23-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 DC74_RS09345 e8146e62288170284853c3a2c7ce270f 226 PIRSF PIRSF001461 1 222 7.8E-97 T 23-04-2016 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 DC74_RS09345 e8146e62288170284853c3a2c7ce270f 226 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 29 43 - T 23-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 DC74_RS09345 e8146e62288170284853c3a2c7ce270f 226 PANTHER PTHR11749 1 219 8.4E-119 T 23-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 DC74_RS09345 e8146e62288170284853c3a2c7ce270f 226 Gene3D G3DSA:3.20.20.70 2 217 4.4E-92 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS09345 e8146e62288170284853c3a2c7ce270f 226 PANTHER PTHR11749:SF3 1 219 8.4E-119 T 23-04-2016 DC74_RS13235 9909a39306daf62bd416f40731d30a8b 556 PANTHER PTHR10357 31 424 5.9E-151 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS13235 9909a39306daf62bd416f40731d30a8b 556 PANTHER PTHR10357 457 518 5.9E-151 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS13235 9909a39306daf62bd416f40731d30a8b 556 SMART SM00642 40 415 2.5E-119 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS13235 9909a39306daf62bd416f40731d30a8b 556 Gene3D G3DSA:3.20.20.80 205 479 6.1E-106 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS13235 9909a39306daf62bd416f40731d30a8b 556 Gene3D G3DSA:3.20.20.80 30 131 6.1E-106 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS13235 9909a39306daf62bd416f40731d30a8b 556 Pfam PF11941 Domain of unknown function (DUF3459) 464 542 4.2E-6 T 23-04-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) DC74_RS13235 9909a39306daf62bd416f40731d30a8b 556 PANTHER PTHR10357:SF11 31 424 5.9E-151 T 23-04-2016 DC74_RS13235 9909a39306daf62bd416f40731d30a8b 556 PANTHER PTHR10357:SF11 457 518 5.9E-151 T 23-04-2016 DC74_RS13235 9909a39306daf62bd416f40731d30a8b 556 Pfam PF00128 Alpha amylase, catalytic domain 55 392 2.1E-74 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS13235 9909a39306daf62bd416f40731d30a8b 556 Gene3D G3DSA:3.90.400.10 132 204 9.8E-28 T 23-04-2016 DC74_RS13235 9909a39306daf62bd416f40731d30a8b 556 SUPERFAMILY SSF51445 31 478 1.51E-124 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS06455 4b4722dd72bd30fd31e9a3effd534e98 104 Gene3D G3DSA:1.10.10.10 8 82 8.5E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06455 4b4722dd72bd30fd31e9a3effd534e98 104 SMART SM00418 16 92 1.0E-14 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS06455 4b4722dd72bd30fd31e9a3effd534e98 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 1.8E-9 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS06455 4b4722dd72bd30fd31e9a3effd534e98 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 1.8E-9 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS06455 4b4722dd72bd30fd31e9a3effd534e98 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 1.8E-9 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS06455 4b4722dd72bd30fd31e9a3effd534e98 104 SUPERFAMILY SSF46785 4 89 2.59E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06455 4b4722dd72bd30fd31e9a3effd534e98 104 Pfam PF12840 Helix-turn-helix domain 16 71 4.9E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS06455 4b4722dd72bd30fd31e9a3effd534e98 104 PANTHER PTHR33154:SF12 1 104 7.5E-29 T 23-04-2016 DC74_RS06455 4b4722dd72bd30fd31e9a3effd534e98 104 PANTHER PTHR33154 1 104 7.5E-29 T 23-04-2016 DC74_RS29515 c68e16aa8f97c47c6f9114b226d4c59f 336 Gene3D G3DSA:3.40.47.10 3 160 1.1E-23 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29515 c68e16aa8f97c47c6f9114b226d4c59f 336 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 245 335 8.0E-14 T 23-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS29515 c68e16aa8f97c47c6f9114b226d4c59f 336 PANTHER PTHR34069:SF2 1 336 2.2E-27 T 23-04-2016 DC74_RS29515 c68e16aa8f97c47c6f9114b226d4c59f 336 Gene3D G3DSA:3.40.47.10 214 335 7.4E-17 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29515 c68e16aa8f97c47c6f9114b226d4c59f 336 Gene3D G3DSA:3.40.47.10 161 181 7.4E-17 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29515 c68e16aa8f97c47c6f9114b226d4c59f 336 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 105 175 2.1E-5 T 23-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS29515 c68e16aa8f97c47c6f9114b226d4c59f 336 PANTHER PTHR34069 1 336 2.2E-27 T 23-04-2016 DC74_RS29515 c68e16aa8f97c47c6f9114b226d4c59f 336 SUPERFAMILY SSF53901 27 335 4.33E-29 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS17830 2ecb18d15bc4ad2fb31461bcf847c894 166 Pfam PF00994 Probable molybdopterin binding domain 8 148 3.3E-28 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS17830 2ecb18d15bc4ad2fb31461bcf847c894 166 Gene3D G3DSA:3.40.980.10 3 155 5.0E-50 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS17830 2ecb18d15bc4ad2fb31461bcf847c894 166 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 5 143 6.3E-30 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS17830 2ecb18d15bc4ad2fb31461bcf847c894 166 SUPERFAMILY SSF53218 4 154 1.44E-40 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS17830 2ecb18d15bc4ad2fb31461bcf847c894 166 SMART SM00852 7 149 2.1E-21 T 23-04-2016 IPR001453 MoaB/Mog domain DC74_RS17830 2ecb18d15bc4ad2fb31461bcf847c894 166 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 65 78 - T 23-04-2016 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 UniPathway: UPA00344 DC74_RS17830 2ecb18d15bc4ad2fb31461bcf847c894 166 PANTHER PTHR10192 1 157 3.0E-61 T 23-04-2016 DC74_RS26060 cf208442cd33b24a6b155365805dee62 288 PANTHER PTHR10992 17 286 3.4E-39 T 23-04-2016 DC74_RS26060 cf208442cd33b24a6b155365805dee62 288 Pfam PF12697 Alpha/beta hydrolase family 41 277 1.1E-16 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS26060 cf208442cd33b24a6b155365805dee62 288 SUPERFAMILY SSF53474 27 285 9.4E-40 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS26060 cf208442cd33b24a6b155365805dee62 288 Gene3D G3DSA:3.40.50.1820 15 285 1.3E-42 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS26060 cf208442cd33b24a6b155365805dee62 288 PANTHER PTHR10992:SF107 17 286 3.4E-39 T 23-04-2016 DC74_RS11690 b982c4b71d89e5e6ae381e9e5b911278 329 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 243 275 5.6E-14 T 23-04-2016 IPR001451 Hexapeptide repeat DC74_RS11690 b982c4b71d89e5e6ae381e9e5b911278 329 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 11 328 4.3E-151 T 23-04-2016 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117|UniPathway: UPA00034 DC74_RS11690 b982c4b71d89e5e6ae381e9e5b911278 329 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 121 161 1.9E-16 T 23-04-2016 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117|UniPathway: UPA00034 DC74_RS11690 b982c4b71d89e5e6ae381e9e5b911278 329 SUPERFAMILY SSF51161 81 309 2.95E-38 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS11690 b982c4b71d89e5e6ae381e9e5b911278 329 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 9 326 43.31 T 23-04-2016 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117|UniPathway: UPA00034 DC74_RS11690 b982c4b71d89e5e6ae381e9e5b911278 329 Gene3D G3DSA:2.160.10.10 162 317 2.3E-33 T 23-04-2016 DC74_RS11690 b982c4b71d89e5e6ae381e9e5b911278 329 Gene3D G3DSA:3.30.60.70 121 161 1.8E-14 T 23-04-2016 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117|UniPathway: UPA00034 DC74_RS38385 6014b9dc7b76ed90677d1faedec533b2 417 Gene3D G3DSA:3.50.50.60 11 78 9.0E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38385 6014b9dc7b76ed90677d1faedec533b2 417 Gene3D G3DSA:3.50.50.60 200 297 9.0E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38385 6014b9dc7b76ed90677d1faedec533b2 417 Gene3D G3DSA:3.50.50.60 382 411 9.0E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38385 6014b9dc7b76ed90677d1faedec533b2 417 Gene3D G3DSA:3.50.50.60 142 167 9.0E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38385 6014b9dc7b76ed90677d1faedec533b2 417 PANTHER PTHR10742:SF287 12 416 1.3E-35 T 23-04-2016 DC74_RS38385 6014b9dc7b76ed90677d1faedec533b2 417 PANTHER PTHR10742 12 416 1.3E-35 T 23-04-2016 DC74_RS38385 6014b9dc7b76ed90677d1faedec533b2 417 SUPERFAMILY SSF51905 370 414 2.81E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38385 6014b9dc7b76ed90677d1faedec533b2 417 SUPERFAMILY SSF51905 10 291 2.81E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38385 6014b9dc7b76ed90677d1faedec533b2 417 Pfam PF01593 Flavin containing amine oxidoreductase 21 411 4.9E-39 T 23-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 DC74_RS06905 c3e28ac0ea87c1ac4fe9196f025d34c9 418 Pfam PF02040 Arsenical pump membrane protein 63 411 1.0E-21 T 23-04-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DC74_RS06905 c3e28ac0ea87c1ac4fe9196f025d34c9 418 PRINTS PR00758 Arsenical pump membrane protein signature 107 131 5.7E-16 T 23-04-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DC74_RS06905 c3e28ac0ea87c1ac4fe9196f025d34c9 418 PRINTS PR00758 Arsenical pump membrane protein signature 385 409 5.7E-16 T 23-04-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DC74_RS06905 c3e28ac0ea87c1ac4fe9196f025d34c9 418 PRINTS PR00758 Arsenical pump membrane protein signature 180 203 5.7E-16 T 23-04-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DC74_RS06905 c3e28ac0ea87c1ac4fe9196f025d34c9 418 PRINTS PR00758 Arsenical pump membrane protein signature 352 377 5.7E-16 T 23-04-2016 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DC74_RS06905 c3e28ac0ea87c1ac4fe9196f025d34c9 418 PANTHER PTHR10283:SF21 1 416 2.5E-90 T 23-04-2016 DC74_RS06905 c3e28ac0ea87c1ac4fe9196f025d34c9 418 PANTHER PTHR10283 1 416 2.5E-90 T 23-04-2016 DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 PANTHER PTHR24319 16 261 4.1E-52 T 23-04-2016 DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 Gene3D G3DSA:3.40.50.720 16 260 3.4E-65 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 PANTHER PTHR24319:SF32 16 261 4.1E-52 T 23-04-2016 DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 SUPERFAMILY SSF51735 16 253 5.16E-62 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 2.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 2.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 2.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 2.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 2.6E-24 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 Pfam PF00106 short chain dehydrogenase 22 217 2.2E-49 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 5.3E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 5.3E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01640 524765cdc102e8d8ce35f426bb7ed340 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 108 5.3E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18240 5ed22326c2b78c0b78bec691743f55cd 208 SUPERFAMILY SSF109854 13 144 1.62E-18 T 23-04-2016 DC74_RS18240 5ed22326c2b78c0b78bec691743f55cd 208 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 16 194 6.0E-49 T 23-04-2016 IPR017520 Conserved hypothetical protein CHP03086 DC74_RS18240 5ed22326c2b78c0b78bec691743f55cd 208 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 205 3.8E-23 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS18240 5ed22326c2b78c0b78bec691743f55cd 208 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 15 138 3.6E-14 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS38205 8257a548459923fac01f32246ba82d3c 230 SUPERFAMILY SSF53474 30 147 3.46E-22 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS38205 8257a548459923fac01f32246ba82d3c 230 Gene3D G3DSA:3.40.50.1820 24 230 1.0E-38 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS38205 8257a548459923fac01f32246ba82d3c 230 Pfam PF01674 Lipase (class 2) 35 221 1.5E-14 T 23-04-2016 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 DC74_RS38205 8257a548459923fac01f32246ba82d3c 230 PANTHER PTHR32015 31 140 6.1E-16 T 23-04-2016 DC74_RS17555 30bbe410db2c6d24bd046e642f980363 341 SUPERFAMILY SSF51735 1 323 1.14E-88 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17555 30bbe410db2c6d24bd046e642f980363 341 PANTHER PTHR10366 3 324 1.7E-99 T 23-04-2016 DC74_RS17555 30bbe410db2c6d24bd046e642f980363 341 Gene3D G3DSA:3.90.25.10 178 325 9.4E-43 T 23-04-2016 DC74_RS17555 30bbe410db2c6d24bd046e642f980363 341 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 5 325 2.0E-114 T 23-04-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|UniPathway: UPA00214 DC74_RS17555 30bbe410db2c6d24bd046e642f980363 341 Gene3D G3DSA:3.40.50.720 1 177 6.1E-48 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17555 30bbe410db2c6d24bd046e642f980363 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 250 3.7E-56 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS17555 30bbe410db2c6d24bd046e642f980363 341 PANTHER PTHR10366:SF186 3 324 1.7E-99 T 23-04-2016 DC74_RS20930 ec23b767ad58b181629c7e5d53d8f6f2 159 SUPERFAMILY SSF55811 4 112 6.09E-19 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS20930 ec23b767ad58b181629c7e5d53d8f6f2 159 Gene3D G3DSA:3.90.79.10 3 112 6.7E-19 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS20930 ec23b767ad58b181629c7e5d53d8f6f2 159 Pfam PF00293 NUDIX domain 9 98 1.2E-13 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS20930 ec23b767ad58b181629c7e5d53d8f6f2 159 PANTHER PTHR22769 7 113 1.0E-12 T 23-04-2016 DC74_RS06960 ebb5bf38dc97a1d92bba13bff71114f7 253 Pfam PF00583 Acetyltransferase (GNAT) family 166 240 3.2E-9 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS06960 ebb5bf38dc97a1d92bba13bff71114f7 253 SUPERFAMILY SSF55729 105 242 6.8E-15 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06960 ebb5bf38dc97a1d92bba13bff71114f7 253 Gene3D G3DSA:3.40.630.30 163 242 5.3E-14 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS08015 6a424840bb165b84b08df7f3df621ec2 319 SUPERFAMILY SSF103481 208 310 4.32E-15 T 23-04-2016 DC74_RS08015 6a424840bb165b84b08df7f3df621ec2 319 SUPERFAMILY SSF103481 54 161 3.4E-6 T 23-04-2016 DC74_RS08015 6a424840bb165b84b08df7f3df621ec2 319 PANTHER PTHR22911 13 312 1.6E-71 T 23-04-2016 DC74_RS08015 6a424840bb165b84b08df7f3df621ec2 319 Pfam PF00892 EamA-like transporter family 13 158 5.1E-8 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS08015 6a424840bb165b84b08df7f3df621ec2 319 Pfam PF00892 EamA-like transporter family 171 306 6.5E-18 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS08015 6a424840bb165b84b08df7f3df621ec2 319 PANTHER PTHR22911:SF46 13 312 1.6E-71 T 23-04-2016 DC74_RS00575 5842e4a3b88f72f910f73a163343e905 539 Gene3D G3DSA:2.30.40.10 6 67 6.0E-12 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS00575 5842e4a3b88f72f910f73a163343e905 539 Gene3D G3DSA:2.30.40.10 503 535 6.0E-12 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS00575 5842e4a3b88f72f910f73a163343e905 539 Gene3D G3DSA:2.30.40.10 476 502 1.1E-5 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS00575 5842e4a3b88f72f910f73a163343e905 539 SUPERFAMILY SSF51338 4 66 1.32E-14 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS00575 5842e4a3b88f72f910f73a163343e905 539 SUPERFAMILY SSF51338 493 537 1.32E-14 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS00575 5842e4a3b88f72f910f73a163343e905 539 SUPERFAMILY SSF51556 153 494 1.17E-27 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS00575 5842e4a3b88f72f910f73a163343e905 539 SUPERFAMILY SSF51556 65 79 1.17E-27 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS00575 5842e4a3b88f72f910f73a163343e905 539 Pfam PF07969 Amidohydrolase family 60 533 4.9E-78 T 23-04-2016 IPR013108 Amidohydrolase 3 DC74_RS00575 5842e4a3b88f72f910f73a163343e905 539 Gene3D G3DSA:3.20.20.140 204 475 2.4E-24 T 23-04-2016 DC74_RS00575 5842e4a3b88f72f910f73a163343e905 539 Gene3D G3DSA:3.20.20.140 69 89 2.4E-24 T 23-04-2016 DC74_RS00575 5842e4a3b88f72f910f73a163343e905 539 PANTHER PTHR22642 6 533 5.6E-114 T 23-04-2016 DC74_RS00575 5842e4a3b88f72f910f73a163343e905 539 PANTHER PTHR22642:SF2 6 533 5.6E-114 T 23-04-2016 DC74_RS15505 c92391f152503da9c7400b8a6a8cee32 301 PANTHER PTHR32243:SF12 24 301 1.5E-159 T 23-04-2016 DC74_RS15505 c92391f152503da9c7400b8a6a8cee32 301 PANTHER PTHR32243 24 301 1.5E-159 T 23-04-2016 DC74_RS15505 c92391f152503da9c7400b8a6a8cee32 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 294 4.8E-21 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS15505 c92391f152503da9c7400b8a6a8cee32 301 Gene3D G3DSA:1.10.3720.10 25 288 4.6E-70 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS15505 c92391f152503da9c7400b8a6a8cee32 301 SUPERFAMILY SSF161098 28 301 3.55E-73 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS04735 94e0fd6379713a4861c064f880b287aa 117 SUPERFAMILY SSF57850 10 82 5.89E-26 T 23-04-2016 DC74_RS04735 94e0fd6379713a4861c064f880b287aa 117 Gene3D G3DSA:3.30.40.10 10 80 9.7E-22 T 23-04-2016 IPR013083 Zinc finger, RING/FYVE/PHD-type DC74_RS04735 94e0fd6379713a4861c064f880b287aa 117 PANTHER PTHR24007 12 111 5.2E-25 T 23-04-2016 DC74_RS04735 94e0fd6379713a4861c064f880b287aa 117 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 18 79 1.2E-11 T 23-04-2016 IPR001607 Zinc finger, UBP-type GO:0008270 DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 Gene3D G3DSA:1.25.60.10 164 276 9.3E-42 T 23-04-2016 DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 Pfam PF00571 CBS domain 355 405 4.5E-6 T 23-04-2016 IPR000644 CBS domain DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 Pfam PF00571 CBS domain 282 343 8.9E-4 T 23-04-2016 IPR000644 CBS domain DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 Pfam PF03448 MgtE intracellular N domain 178 278 4.9E-28 T 23-04-2016 IPR006668 Magnesium transporter, MgtE intracellular domain DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 Gene3D G3DSA:3.10.580.10 279 405 3.1E-20 T 23-04-2016 DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 SMART SM00924 178 281 8.9E-36 T 23-04-2016 IPR006668 Magnesium transporter, MgtE intracellular domain DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 SUPERFAMILY SSF158791 166 278 2.22E-32 T 23-04-2016 DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 SUPERFAMILY SSF54631 280 412 5.43E-24 T 23-04-2016 DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 PANTHER PTHR11911:SF108 254 423 1.3E-49 T 23-04-2016 DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 PANTHER PTHR11911:SF108 195 203 1.3E-49 T 23-04-2016 DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 SMART SM00116 357 405 0.0027 T 23-04-2016 IPR000644 CBS domain DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 PANTHER PTHR11911 254 423 1.3E-49 T 23-04-2016 DC74_RS26010 cc4a565c4f3e095a45aa81a8a9c81a0d 441 PANTHER PTHR11911 195 203 1.3E-49 T 23-04-2016 DC74_RS19850 25a69a3d4671aa18aa802d6d0c03e9cf 250 Pfam PF00326 Prolyl oligopeptidase family 91 214 2.9E-9 T 23-04-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 DC74_RS19850 25a69a3d4671aa18aa802d6d0c03e9cf 250 Gene3D G3DSA:3.40.50.1820 16 233 3.6E-38 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS19850 25a69a3d4671aa18aa802d6d0c03e9cf 250 SUPERFAMILY SSF53474 12 239 1.02E-37 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS00775 abbcaa9fdecf190012bc32f0977b257b 309 SUPERFAMILY SSF53474 18 304 5.27E-65 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS00775 abbcaa9fdecf190012bc32f0977b257b 309 Gene3D G3DSA:3.40.50.1820 16 308 1.5E-80 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS00775 abbcaa9fdecf190012bc32f0977b257b 309 PANTHER PTHR23024 60 305 6.5E-70 T 23-04-2016 DC74_RS00775 abbcaa9fdecf190012bc32f0977b257b 309 Pfam PF07859 alpha/beta hydrolase fold 76 283 2.4E-61 T 23-04-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 DC74_RS00775 abbcaa9fdecf190012bc32f0977b257b 309 PANTHER PTHR23024:SF24 60 305 6.5E-70 T 23-04-2016 DC74_RS39950 1ac3231a4719ac88dbff3ec823848b45 313 Gene3D G3DSA:3.90.1200.10 102 227 1.3E-5 T 23-04-2016 DC74_RS39950 1ac3231a4719ac88dbff3ec823848b45 313 Pfam PF01636 Phosphotransferase enzyme family 35 228 1.6E-12 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS39950 1ac3231a4719ac88dbff3ec823848b45 313 SUPERFAMILY SSF56112 32 227 1.06E-15 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS21150 7a79119614b14345c6ee812b1b422dd4 521 SUPERFAMILY SSF103473 258 480 9.02E-64 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21150 7a79119614b14345c6ee812b1b422dd4 521 SUPERFAMILY SSF103473 18 210 9.02E-64 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21150 7a79119614b14345c6ee812b1b422dd4 521 PANTHER PTHR23501 21 477 6.2E-141 T 23-04-2016 DC74_RS21150 7a79119614b14345c6ee812b1b422dd4 521 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 8.9E-9 T 23-04-2016 DC74_RS21150 7a79119614b14345c6ee812b1b422dd4 521 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 8.9E-9 T 23-04-2016 DC74_RS21150 7a79119614b14345c6ee812b1b422dd4 521 PRINTS PR01036 Tetracycline resistance protein TetB signature 312 336 8.9E-9 T 23-04-2016 DC74_RS21150 7a79119614b14345c6ee812b1b422dd4 521 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 8.9E-9 T 23-04-2016 DC74_RS21150 7a79119614b14345c6ee812b1b422dd4 521 Pfam PF07690 Major Facilitator Superfamily 29 420 6.3E-50 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS21150 7a79119614b14345c6ee812b1b422dd4 521 Gene3D G3DSA:1.20.1250.20 273 479 6.8E-20 T 23-04-2016 DC74_RS21150 7a79119614b14345c6ee812b1b422dd4 521 Gene3D G3DSA:1.20.1250.20 21 198 8.7E-29 T 23-04-2016 DC74_RS21150 7a79119614b14345c6ee812b1b422dd4 521 PANTHER PTHR23501:SF7 21 477 6.2E-141 T 23-04-2016 DC74_RS21150 7a79119614b14345c6ee812b1b422dd4 521 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 428 7.9E-74 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS29240 8fdda9577cec5368f07b7719593fa86b 662 Pfam PF02254 TrkA-N domain 89 156 8.5E-8 T 23-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 DC74_RS29240 8fdda9577cec5368f07b7719593fa86b 662 Pfam PF02254 TrkA-N domain 412 520 1.6E-19 T 23-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 DC74_RS29240 8fdda9577cec5368f07b7719593fa86b 662 SUPERFAMILY SSF51735 408 557 1.44E-23 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29240 8fdda9577cec5368f07b7719593fa86b 662 PANTHER PTHR16254 350 576 2.9E-43 T 23-04-2016 DC74_RS29240 8fdda9577cec5368f07b7719593fa86b 662 SUPERFAMILY SSF51735 91 155 5.01E-9 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29240 8fdda9577cec5368f07b7719593fa86b 662 PANTHER PTHR16254:SF8 350 576 2.9E-43 T 23-04-2016 DC74_RS29240 8fdda9577cec5368f07b7719593fa86b 662 Gene3D G3DSA:3.40.50.720 89 156 6.0E-16 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29240 8fdda9577cec5368f07b7719593fa86b 662 Gene3D G3DSA:3.40.50.720 1 41 6.0E-16 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29240 8fdda9577cec5368f07b7719593fa86b 662 Gene3D G3DSA:3.40.50.720 409 561 6.9E-31 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02025 ed13032ad5f29c723f45c52b563b680d 303 SUPERFAMILY SSF55729 198 285 3.88E-5 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS08340 443abb3b48d67d0ff78ea37158e39dc6 488 SUPERFAMILY SSF55785 115 217 1.08E-13 T 23-04-2016 IPR000014 PAS domain DC74_RS08340 443abb3b48d67d0ff78ea37158e39dc6 488 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 298 486 3.0E-45 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS08340 443abb3b48d67d0ff78ea37158e39dc6 488 SMART SM00331 272 486 4.1E-20 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS08340 443abb3b48d67d0ff78ea37158e39dc6 488 PANTHER PTHR21021 240 486 3.4E-34 T 23-04-2016 DC74_RS08340 443abb3b48d67d0ff78ea37158e39dc6 488 PANTHER PTHR21021 131 142 3.4E-34 T 23-04-2016 DC74_RS08340 443abb3b48d67d0ff78ea37158e39dc6 488 Pfam PF08447 PAS fold 126 209 1.1E-13 T 23-04-2016 IPR013655 PAS fold-3 GO:0005515 DC74_RS08340 443abb3b48d67d0ff78ea37158e39dc6 488 SUPERFAMILY SSF81606 288 486 1.73E-5 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS08340 443abb3b48d67d0ff78ea37158e39dc6 488 Gene3D G3DSA:3.30.450.20 114 217 2.4E-14 T 23-04-2016 DC74_RS08340 443abb3b48d67d0ff78ea37158e39dc6 488 SMART SM00086 177 219 2.0E-5 T 23-04-2016 IPR001610 PAC motif DC74_RS08340 443abb3b48d67d0ff78ea37158e39dc6 488 PANTHER PTHR21021:SF19 240 486 3.4E-34 T 23-04-2016 DC74_RS08340 443abb3b48d67d0ff78ea37158e39dc6 488 PANTHER PTHR21021:SF19 131 142 3.4E-34 T 23-04-2016 DC74_RS12835 3fbb5e31702353ab5f15a1c828347972 93 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 2.4E-18 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS12835 3fbb5e31702353ab5f15a1c828347972 93 SUPERFAMILY SSF54909 3 78 2.47E-19 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS12835 3fbb5e31702353ab5f15a1c828347972 93 Gene3D G3DSA:3.30.70.920 5 78 2.5E-25 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS12835 3fbb5e31702353ab5f15a1c828347972 93 PANTHER PTHR30154 2 84 5.0E-20 T 23-04-2016 DC74_RS05370 97d5bb47ed6a51ed57fe2d5f6300cf56 315 SUPERFAMILY SSF56645 6 107 1.21E-10 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS05370 97d5bb47ed6a51ed57fe2d5f6300cf56 315 PANTHER PTHR10909 175 289 4.8E-16 T 23-04-2016 DC74_RS05370 97d5bb47ed6a51ed57fe2d5f6300cf56 315 SUPERFAMILY SSF47203 171 294 3.06E-26 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS05370 97d5bb47ed6a51ed57fe2d5f6300cf56 315 Gene3D G3DSA:1.20.140.10 165 291 2.2E-23 T 23-04-2016 DC74_RS05370 97d5bb47ed6a51ed57fe2d5f6300cf56 315 Gene3D G3DSA:1.10.540.10 7 86 1.4E-10 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS05370 97d5bb47ed6a51ed57fe2d5f6300cf56 315 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 168 289 5.1E-19 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS05370 97d5bb47ed6a51ed57fe2d5f6300cf56 315 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 82 2.5E-9 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS23770 0967d5d377cf25d9cc9087d4589cbe54 490 PANTHER PTHR11119 24 470 1.1E-118 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS23770 0967d5d377cf25d9cc9087d4589cbe54 490 PANTHER PTHR11119:SF9 24 470 1.1E-118 T 23-04-2016 IPR029940 AzgA purine transporter GO:0005345|GO:0006863 DC74_RS23770 0967d5d377cf25d9cc9087d4589cbe54 490 Pfam PF00860 Permease family 41 442 4.1E-33 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS18465 f9e745e98f0fbf49f774f25bedd10f06 223 Pfam PF03473 MOSC domain 58 171 3.7E-25 T 23-04-2016 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 DC74_RS18465 f9e745e98f0fbf49f774f25bedd10f06 223 SUPERFAMILY SSF50800 2 219 1.31E-56 T 23-04-2016 IPR011037 Pyruvate kinase-like, insert domain DC74_RS18465 f9e745e98f0fbf49f774f25bedd10f06 223 Gene3D G3DSA:2.40.33.20 2 219 2.1E-72 T 23-04-2016 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like DC74_RS18465 f9e745e98f0fbf49f774f25bedd10f06 223 PANTHER PTHR30212 1 220 2.6E-49 T 23-04-2016 DC74_RS17095 53bf4ac0fe50d53cb6e090a2a98dcbe4 247 Gene3D G3DSA:3.40.50.10190 103 165 3.7E-6 T 23-04-2016 IPR001357 BRCT domain DC74_RS17095 53bf4ac0fe50d53cb6e090a2a98dcbe4 247 Pfam PF11774 Lsr2 196 233 1.3E-8 T 23-04-2016 IPR024412 Lsr2 DC74_RS17095 53bf4ac0fe50d53cb6e090a2a98dcbe4 247 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 187 236 0.001 T 23-04-2016 IPR024412 Lsr2 DC74_RS27595 8f7f5c76ad753926ee9e14790fc7adb6 497 PANTHER PTHR11895:SF7 1 489 1.1E-213 T 23-04-2016 DC74_RS27595 8f7f5c76ad753926ee9e14790fc7adb6 497 ProSitePatterns PS00571 Amidases signature. 153 184 - T 23-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS27595 8f7f5c76ad753926ee9e14790fc7adb6 497 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 483 90.243 T 23-04-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS27595 8f7f5c76ad753926ee9e14790fc7adb6 497 SUPERFAMILY SSF75304 2 482 2.75E-158 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS27595 8f7f5c76ad753926ee9e14790fc7adb6 497 Pfam PF01425 Amidase 25 471 6.3E-158 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS27595 8f7f5c76ad753926ee9e14790fc7adb6 497 Gene3D G3DSA:3.90.1300.10 2 487 2.8E-173 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS27595 8f7f5c76ad753926ee9e14790fc7adb6 497 PANTHER PTHR11895 1 489 1.1E-213 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS27595 8f7f5c76ad753926ee9e14790fc7adb6 497 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 14 482 1.1E-185 T 23-04-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS34780 ddf082c910b6b0502c6c6e2d5ed3694d 428 SMART SM00636 62 417 1.1E-110 T 23-04-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 DC74_RS34780 ddf082c910b6b0502c6c6e2d5ed3694d 428 PANTHER PTHR11177 141 428 2.2E-89 T 23-04-2016 DC74_RS34780 ddf082c910b6b0502c6c6e2d5ed3694d 428 PANTHER PTHR11177 60 116 2.2E-89 T 23-04-2016 DC74_RS34780 ddf082c910b6b0502c6c6e2d5ed3694d 428 PANTHER PTHR11177 13 39 2.2E-89 T 23-04-2016 DC74_RS34780 ddf082c910b6b0502c6c6e2d5ed3694d 428 Pfam PF00704 Glycosyl hydrolases family 18 63 417 2.6E-73 T 23-04-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 DC74_RS34780 ddf082c910b6b0502c6c6e2d5ed3694d 428 ProSitePatterns PS01095 Chitinases family 18 active site. 198 206 - T 23-04-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 DC74_RS34780 ddf082c910b6b0502c6c6e2d5ed3694d 428 SUPERFAMILY SSF54556 329 388 8.66E-12 T 23-04-2016 IPR029070 Chitinase insertion domain DC74_RS34780 ddf082c910b6b0502c6c6e2d5ed3694d 428 Gene3D G3DSA:3.10.50.10 331 389 8.3E-22 T 23-04-2016 IPR029070 Chitinase insertion domain DC74_RS34780 ddf082c910b6b0502c6c6e2d5ed3694d 428 SUPERFAMILY SSF51445 58 327 6.61E-82 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS34780 ddf082c910b6b0502c6c6e2d5ed3694d 428 SUPERFAMILY SSF51445 387 425 6.61E-82 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS34780 ddf082c910b6b0502c6c6e2d5ed3694d 428 Gene3D G3DSA:3.20.20.80 46 330 1.2E-87 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS34780 ddf082c910b6b0502c6c6e2d5ed3694d 428 Gene3D G3DSA:3.20.20.80 394 427 1.2E-87 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS00480 53d754ac684560a31c18bfc07c09997a 137 PANTHER PTHR11717 1 134 4.0E-39 T 23-04-2016 DC74_RS00480 53d754ac684560a31c18bfc07c09997a 137 SUPERFAMILY SSF52788 4 128 9.55E-37 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS00480 53d754ac684560a31c18bfc07c09997a 137 SMART SM00226 5 130 4.8E-46 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS00480 53d754ac684560a31c18bfc07c09997a 137 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 127 4.9E-21 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS00480 53d754ac684560a31c18bfc07c09997a 137 PANTHER PTHR11717:SF18 1 134 4.0E-39 T 23-04-2016 DC74_RS00480 53d754ac684560a31c18bfc07c09997a 137 Gene3D G3DSA:3.40.50.270 4 128 1.2E-40 T 23-04-2016 DC74_RS03310 81724ca673f23fc06796da97b59415cd 220 Pfam PF01966 HD domain 36 125 6.0E-6 T 23-04-2016 IPR006674 HD domain DC74_RS03310 81724ca673f23fc06796da97b59415cd 220 Gene3D G3DSA:1.10.3210.10 30 128 2.7E-9 T 23-04-2016 IPR006674 HD domain DC74_RS03310 81724ca673f23fc06796da97b59415cd 220 PANTHER PTHR35569 5 219 8.5E-24 T 23-04-2016 DC74_RS03310 81724ca673f23fc06796da97b59415cd 220 SUPERFAMILY SSF109604 28 126 4.4E-13 T 23-04-2016 DC74_RS00835 259ed5d6c45c73e81ba73a5251937e3f 318 PANTHER PTHR30346 1 310 7.0E-72 T 23-04-2016 DC74_RS00835 259ed5d6c45c73e81ba73a5251937e3f 318 Gene3D G3DSA:1.10.10.10 1 78 3.5E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00835 259ed5d6c45c73e81ba73a5251937e3f 318 PANTHER PTHR30346:SF0 1 310 7.0E-72 T 23-04-2016 DC74_RS00835 259ed5d6c45c73e81ba73a5251937e3f 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.4E-19 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00835 259ed5d6c45c73e81ba73a5251937e3f 318 SUPERFAMILY SSF46785 1 81 1.66E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00835 259ed5d6c45c73e81ba73a5251937e3f 318 Gene3D G3DSA:3.40.190.10 88 176 4.2E-23 T 23-04-2016 DC74_RS00835 259ed5d6c45c73e81ba73a5251937e3f 318 Gene3D G3DSA:3.40.190.10 177 263 6.2E-10 T 23-04-2016 DC74_RS00835 259ed5d6c45c73e81ba73a5251937e3f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00835 259ed5d6c45c73e81ba73a5251937e3f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00835 259ed5d6c45c73e81ba73a5251937e3f 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00835 259ed5d6c45c73e81ba73a5251937e3f 318 SUPERFAMILY SSF53850 88 297 7.93E-29 T 23-04-2016 DC74_RS00835 259ed5d6c45c73e81ba73a5251937e3f 318 Pfam PF03466 LysR substrate binding domain 87 293 3.6E-29 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS08255 cdc474590eb36600e2d40a468031323b 267 SMART SM00346 21 110 6.2E-24 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS08255 cdc474590eb36600e2d40a468031323b 267 Pfam PF09339 IclR helix-turn-helix domain 23 72 2.6E-15 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS08255 cdc474590eb36600e2d40a468031323b 267 Gene3D G3DSA:3.30.450.40 93 265 8.4E-56 T 23-04-2016 IPR029016 GAF domain-like DC74_RS08255 cdc474590eb36600e2d40a468031323b 267 PANTHER PTHR30136 20 267 4.3E-68 T 23-04-2016 DC74_RS08255 cdc474590eb36600e2d40a468031323b 267 PANTHER PTHR30136:SF7 20 267 4.3E-68 T 23-04-2016 DC74_RS08255 cdc474590eb36600e2d40a468031323b 267 SUPERFAMILY SSF46785 21 90 2.97E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08255 cdc474590eb36600e2d40a468031323b 267 SUPERFAMILY SSF55781 78 265 3.04E-51 T 23-04-2016 IPR029016 GAF domain-like DC74_RS08255 cdc474590eb36600e2d40a468031323b 267 Gene3D G3DSA:1.10.10.10 19 91 1.9E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08255 cdc474590eb36600e2d40a468031323b 267 Pfam PF01614 Bacterial transcriptional regulator 138 261 7.5E-32 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS04380 a0389350b1cd9118ea82c7e7bc2d3267 229 PANTHER PTHR33393:SF4 68 227 3.5E-37 T 23-04-2016 DC74_RS04380 a0389350b1cd9118ea82c7e7bc2d3267 229 Gene3D G3DSA:2.40.260.10 84 204 1.4E-7 T 23-04-2016 IPR023365 Sortase domain DC74_RS04380 a0389350b1cd9118ea82c7e7bc2d3267 229 SUPERFAMILY SSF63817 76 206 7.46E-14 T 23-04-2016 IPR023365 Sortase domain DC74_RS04380 a0389350b1cd9118ea82c7e7bc2d3267 229 PANTHER PTHR33393 68 227 3.5E-37 T 23-04-2016 DC74_RS04380 a0389350b1cd9118ea82c7e7bc2d3267 229 Pfam PF04203 Sortase family 83 223 4.2E-15 T 23-04-2016 IPR005754 Sortase family DC74_RS19815 3cfc0c8a417ad5879d08f5593407aa50 428 Gene3D G3DSA:3.90.170.10 266 422 5.8E-68 T 23-04-2016 DC74_RS19815 3cfc0c8a417ad5879d08f5593407aa50 428 PANTHER PTHR11846 5 426 2.3E-235 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 DC74_RS19815 3cfc0c8a417ad5879d08f5593407aa50 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 23-04-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|UniPathway: UPA00075 DC74_RS19815 3cfc0c8a417ad5879d08f5593407aa50 428 SUPERFAMILY SSF52540 3 425 1.59E-172 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS19815 3cfc0c8a417ad5879d08f5593407aa50 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 198.626 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 DC74_RS19815 3cfc0c8a417ad5879d08f5593407aa50 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 423 3.7E-166 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 DC74_RS19815 3cfc0c8a417ad5879d08f5593407aa50 428 SMART SM00788 3 422 1.2E-282 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 DC74_RS19815 3cfc0c8a417ad5879d08f5593407aa50 428 Gene3D G3DSA:1.10.300.10 101 193 1.7E-32 T 23-04-2016 DC74_RS19815 3cfc0c8a417ad5879d08f5593407aa50 428 Gene3D G3DSA:3.40.440.10 194 264 3.9E-70 T 23-04-2016 DC74_RS19815 3cfc0c8a417ad5879d08f5593407aa50 428 Gene3D G3DSA:3.40.440.10 4 93 3.9E-70 T 23-04-2016 DC74_RS19815 3cfc0c8a417ad5879d08f5593407aa50 428 Pfam PF00709 Adenylosuccinate synthetase 5 421 2.7E-175 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 DC74_RS19815 3cfc0c8a417ad5879d08f5593407aa50 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-04-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 SUPERFAMILY SSF55909 2 407 1.51E-127 T 23-04-2016 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 Gene3D G3DSA:3.75.10.10 151 407 5.5E-128 T 23-04-2016 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 Gene3D G3DSA:3.75.10.10 2 66 5.5E-128 T 23-04-2016 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 Hamap MF_00242 Arginine deiminase [arcA]. 1 407 42.658 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PRINTS PR01466 Bacterial arginine deiminase signature 179 194 5.7E-49 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PRINTS PR01466 Bacterial arginine deiminase signature 343 360 5.7E-49 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PRINTS PR01466 Bacterial arginine deiminase signature 386 404 5.7E-49 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PRINTS PR01466 Bacterial arginine deiminase signature 151 169 5.7E-49 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PRINTS PR01466 Bacterial arginine deiminase signature 1 20 5.7E-49 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PRINTS PR01466 Bacterial arginine deiminase signature 363 377 5.7E-49 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 Pfam PF02274 Amidinotransferase 17 404 4.1E-88 T 23-04-2016 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PANTHER PTHR12737:SF13 3 90 5.1E-113 T 23-04-2016 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PANTHER PTHR12737:SF13 310 409 5.1E-113 T 23-04-2016 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PANTHER PTHR12737:SF13 151 291 5.1E-113 T 23-04-2016 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PANTHER PTHR12737 3 90 5.1E-113 T 23-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PANTHER PTHR12737 310 409 5.1E-113 T 23-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PANTHER PTHR12737 151 291 5.1E-113 T 23-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS29340 c090eed82cce0d8c7ec532bf51b2142c 411 PIRSF PIRSF006356 1 407 1.1E-152 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 DC74_RS30390 1eeb7c7afa86ad8e72f747d52ed3d342 597 Gene3D G3DSA:3.40.50.300 142 233 4.6E-30 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30390 1eeb7c7afa86ad8e72f747d52ed3d342 597 Gene3D G3DSA:3.40.50.300 368 561 4.6E-30 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30390 1eeb7c7afa86ad8e72f747d52ed3d342 597 Pfam PF12696 TraM recognition site of TraD and TraG 420 538 1.7E-31 T 23-04-2016 IPR032689 TraD/TraG, TraM recognition site DC74_RS30390 1eeb7c7afa86ad8e72f747d52ed3d342 597 SUPERFAMILY SSF52540 145 562 1.43E-40 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10315 3929544722ca2d86accf9532ddf3eae7 281 Gene3D G3DSA:3.60.20.10 54 262 2.4E-55 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS10315 3929544722ca2d86accf9532ddf3eae7 281 SUPERFAMILY SSF56235 47 264 6.11E-58 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS10315 3929544722ca2d86accf9532ddf3eae7 281 Hamap MF_02113_B Proteasome subunit beta [prcB]. 7 275 49.733 T 23-04-2016 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 UniPathway: UPA00997 DC74_RS10315 3929544722ca2d86accf9532ddf3eae7 281 PANTHER PTHR11599:SF58 7 274 1.2E-135 T 23-04-2016 DC74_RS10315 3929544722ca2d86accf9532ddf3eae7 281 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 50 269 3.9E-116 T 23-04-2016 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 UniPathway: UPA00997 DC74_RS10315 3929544722ca2d86accf9532ddf3eae7 281 PANTHER PTHR11599 7 274 1.2E-135 T 23-04-2016 DC74_RS10315 3929544722ca2d86accf9532ddf3eae7 281 Pfam PF00227 Proteasome subunit 52 230 1.4E-36 T 23-04-2016 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: REACT_11045|Reactome: REACT_13|Reactome: REACT_13635|Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_383|Reactome: REACT_578|Reactome: REACT_6185|Reactome: REACT_6850 DC74_RS23865 06ac080847582e05aed7a6f6b659ccd7 532 PANTHER PTHR22855:SF31 6 532 0.0 T 23-04-2016 DC74_RS23865 06ac080847582e05aed7a6f6b659ccd7 532 SUPERFAMILY SSF52096 232 512 9.37E-76 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS23865 06ac080847582e05aed7a6f6b659ccd7 532 SUPERFAMILY SSF52096 22 264 4.83E-64 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS23865 06ac080847582e05aed7a6f6b659ccd7 532 Pfam PF01039 Carboxyl transferase domain 48 520 2.7E-134 T 23-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 DC74_RS23865 06ac080847582e05aed7a6f6b659ccd7 532 Gene3D G3DSA:3.90.226.10 274 521 5.7E-78 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS23865 06ac080847582e05aed7a6f6b659ccd7 532 Gene3D G3DSA:3.90.226.10 33 265 5.7E-63 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS23865 06ac080847582e05aed7a6f6b659ccd7 532 PANTHER PTHR22855 6 532 0.0 T 23-04-2016 DC74_RS07815 fb626b3c557da1647d5b69e587607307 283 SUPERFAMILY SSF53335 18 259 6.66E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS07815 fb626b3c557da1647d5b69e587607307 283 Pfam PF13649 Methyltransferase domain 99 183 1.5E-6 T 23-04-2016 DC74_RS07815 fb626b3c557da1647d5b69e587607307 283 Gene3D G3DSA:3.40.50.150 77 200 3.9E-14 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS07815 fb626b3c557da1647d5b69e587607307 283 PANTHER PTHR10108:SF886 35 282 4.4E-15 T 23-04-2016 DC74_RS07815 fb626b3c557da1647d5b69e587607307 283 PIRSF PIRSF018249 6 283 3.1E-85 T 23-04-2016 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 DC74_RS07815 fb626b3c557da1647d5b69e587607307 283 PANTHER PTHR10108 35 282 4.4E-15 T 23-04-2016 DC74_RS03960 b238686993b9f92b4f4a5b60873344a7 73 Gene3D G3DSA:3.30.70.20 1 63 7.3E-14 T 23-04-2016 DC74_RS03960 b238686993b9f92b4f4a5b60873344a7 73 SUPERFAMILY SSF54862 3 60 2.28E-11 T 23-04-2016 DC74_RS03960 b238686993b9f92b4f4a5b60873344a7 73 Pfam PF13459 4Fe-4S single cluster domain 3 60 9.8E-13 T 23-04-2016 DC74_RS03960 b238686993b9f92b4f4a5b60873344a7 73 PANTHER PTHR36923 1 70 8.4E-16 T 23-04-2016 DC74_RS33460 458c820023fa356d9b337f9c3423c9a6 298 PANTHER PTHR37418 5 91 2.6E-153 T 23-04-2016 DC74_RS33460 458c820023fa356d9b337f9c3423c9a6 298 PANTHER PTHR37418 109 297 2.6E-153 T 23-04-2016 DC74_RS33460 458c820023fa356d9b337f9c3423c9a6 298 Pfam PF05853 beta-keto acid cleavage enzyme 8 294 1.5E-102 T 23-04-2016 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24|UniPathway: UPA00870 DC74_RS33460 458c820023fa356d9b337f9c3423c9a6 298 PANTHER PTHR37418:SF2 5 91 2.6E-153 T 23-04-2016 DC74_RS33460 458c820023fa356d9b337f9c3423c9a6 298 PANTHER PTHR37418:SF2 109 297 2.6E-153 T 23-04-2016 DC74_RS33460 458c820023fa356d9b337f9c3423c9a6 298 Gene3D G3DSA:3.20.20.70 7 296 3.1E-116 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS01205 438438dc47a552c045087b710d5411f8 215 Pfam PF00571 CBS domain 73 125 1.9E-13 T 23-04-2016 IPR000644 CBS domain DC74_RS01205 438438dc47a552c045087b710d5411f8 215 Pfam PF00571 CBS domain 6 60 2.4E-10 T 23-04-2016 IPR000644 CBS domain DC74_RS01205 438438dc47a552c045087b710d5411f8 215 SMART SM00116 78 126 1.1E-13 T 23-04-2016 IPR000644 CBS domain DC74_RS01205 438438dc47a552c045087b710d5411f8 215 SMART SM00116 13 61 3.2E-7 T 23-04-2016 IPR000644 CBS domain DC74_RS01205 438438dc47a552c045087b710d5411f8 215 Gene3D G3DSA:3.20.20.70 2 128 1.9E-32 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS01205 438438dc47a552c045087b710d5411f8 215 SUPERFAMILY SSF54631 2 125 1.39E-33 T 23-04-2016 DC74_RS01205 438438dc47a552c045087b710d5411f8 215 PANTHER PTHR11911 5 153 2.2E-26 T 23-04-2016 DC74_RS01205 438438dc47a552c045087b710d5411f8 215 Pfam PF04972 BON domain 129 194 5.4E-10 T 23-04-2016 IPR007055 BON domain DC74_RS23255 ceefdd63e060d12ada4c98da6e9923b5 143 SUPERFAMILY SSF55811 3 135 1.16E-26 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS23255 ceefdd63e060d12ada4c98da6e9923b5 143 Gene3D G3DSA:3.90.79.10 4 129 2.0E-27 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS23255 ceefdd63e060d12ada4c98da6e9923b5 143 Pfam PF00293 NUDIX domain 6 126 2.2E-15 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS23255 ceefdd63e060d12ada4c98da6e9923b5 143 PANTHER PTHR22769:SF27 4 123 3.9E-28 T 23-04-2016 DC74_RS23255 ceefdd63e060d12ada4c98da6e9923b5 143 PANTHER PTHR22769 4 123 3.9E-28 T 23-04-2016 DC74_RS23255 ceefdd63e060d12ada4c98da6e9923b5 143 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS26900 788d03b1873279b82e0b3606eb795a1e 408 Gene3D G3DSA:3.90.1150.10 277 385 5.1E-32 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS26900 788d03b1873279b82e0b3606eb795a1e 408 PIRSF PIRSF000412 1 398 3.5E-145 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS26900 788d03b1873279b82e0b3606eb795a1e 408 SUPERFAMILY SSF53383 2 405 5.44E-145 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS26900 788d03b1873279b82e0b3606eb795a1e 408 PANTHER PTHR11680:SF0 1 404 2.5E-171 T 23-04-2016 DC74_RS26900 788d03b1873279b82e0b3606eb795a1e 408 PANTHER PTHR11680 1 404 2.5E-171 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS26900 788d03b1873279b82e0b3606eb795a1e 408 Pfam PF00464 Serine hydroxymethyltransferase 3 380 5.0E-132 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS26900 788d03b1873279b82e0b3606eb795a1e 408 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 1 405 45.633 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 DC74_RS26900 788d03b1873279b82e0b3606eb795a1e 408 Gene3D G3DSA:3.40.640.10 30 276 8.1E-93 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS16770 bd66cb518153f545c834bb2cb590167b 656 Pfam PF00535 Glycosyl transferase family 2 31 163 3.1E-28 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS16770 bd66cb518153f545c834bb2cb590167b 656 Gene3D G3DSA:3.90.550.10 28 243 4.1E-44 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS16770 bd66cb518153f545c834bb2cb590167b 656 PANTHER PTHR22916 27 351 3.8E-42 T 23-04-2016 DC74_RS16770 bd66cb518153f545c834bb2cb590167b 656 SUPERFAMILY SSF53448 27 237 2.21E-47 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS22690 8e45da45ef3fd09ecf2360bb9f48f3c8 330 SUPERFAMILY SSF51735 1 301 2.25E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS22690 8e45da45ef3fd09ecf2360bb9f48f3c8 330 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 210 1.7E-8 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS22690 8e45da45ef3fd09ecf2360bb9f48f3c8 330 PANTHER PTHR10366:SF430 2 324 1.7E-59 T 23-04-2016 DC74_RS22690 8e45da45ef3fd09ecf2360bb9f48f3c8 330 Gene3D G3DSA:3.40.50.720 1 298 4.4E-22 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS22690 8e45da45ef3fd09ecf2360bb9f48f3c8 330 PANTHER PTHR10366 2 324 1.7E-59 T 23-04-2016 DC74_RS32650 d4f449f9d07e502031e51c06376fa605 550 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 16 434 2.5E-22 T 23-04-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 DC74_RS32650 d4f449f9d07e502031e51c06376fa605 550 Gene3D G3DSA:3.40.720.10 5 157 4.8E-40 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 DC74_RS32650 d4f449f9d07e502031e51c06376fa605 550 Gene3D G3DSA:3.40.720.10 274 393 4.8E-40 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 DC74_RS32650 d4f449f9d07e502031e51c06376fa605 550 SUPERFAMILY SSF53649 219 224 9.16E-30 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS32650 d4f449f9d07e502031e51c06376fa605 550 SUPERFAMILY SSF53649 3 113 9.16E-30 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS32650 d4f449f9d07e502031e51c06376fa605 550 SUPERFAMILY SSF53649 275 530 9.16E-30 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS03820 c7e91314eb54c93bb16fb60e096a97d2 137 SUPERFAMILY SSF51182 31 123 3.06E-14 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS03820 c7e91314eb54c93bb16fb60e096a97d2 137 Gene3D G3DSA:2.60.120.10 46 122 4.6E-12 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS25240 2de18ba2210328e8444fa006cf18ca00 338 PANTHER PTHR24220:SF0 6 243 4.2E-100 T 23-04-2016 DC74_RS25240 2de18ba2210328e8444fa006cf18ca00 338 Pfam PF13732 Domain of unknown function (DUF4162) 217 307 6.7E-8 T 23-04-2016 IPR025302 Domain of unknown function DUF4162 DC74_RS25240 2de18ba2210328e8444fa006cf18ca00 338 SMART SM00382 29 228 1.2E-8 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS25240 2de18ba2210328e8444fa006cf18ca00 338 SUPERFAMILY SSF52540 5 225 5.77E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25240 2de18ba2210328e8444fa006cf18ca00 338 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS25240 2de18ba2210328e8444fa006cf18ca00 338 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 3.6E-108 T 23-04-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 KEGG: 00920+3.6.3.- DC74_RS25240 2de18ba2210328e8444fa006cf18ca00 338 Pfam PF00005 ABC transporter 20 163 1.4E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS25240 2de18ba2210328e8444fa006cf18ca00 338 PANTHER PTHR24220 6 243 4.2E-100 T 23-04-2016 DC74_RS25240 2de18ba2210328e8444fa006cf18ca00 338 Gene3D G3DSA:3.40.50.300 3 234 4.9E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06320 0be21481ecfc4fa833b17b2f2e44c941 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 72 9.4E-14 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS06320 0be21481ecfc4fa833b17b2f2e44c941 210 Gene3D G3DSA:1.10.357.10 7 207 3.9E-29 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS06320 0be21481ecfc4fa833b17b2f2e44c941 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.5E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS06320 0be21481ecfc4fa833b17b2f2e44c941 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.5E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS06320 0be21481ecfc4fa833b17b2f2e44c941 210 SUPERFAMILY SSF46689 14 79 6.16E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06320 0be21481ecfc4fa833b17b2f2e44c941 210 SUPERFAMILY SSF48498 93 205 1.72E-7 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS06320 0be21481ecfc4fa833b17b2f2e44c941 210 PANTHER PTHR30055 7 205 7.2E-22 T 23-04-2016 DC74_RS38065 992d8172a9abcdb59ae1a3ea973a666b 343 PANTHER PTHR10366 12 326 5.3E-69 T 23-04-2016 DC74_RS38065 992d8172a9abcdb59ae1a3ea973a666b 343 Pfam PF01370 NAD dependent epimerase/dehydratase family 13 260 5.6E-44 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS38065 992d8172a9abcdb59ae1a3ea973a666b 343 Gene3D G3DSA:3.90.25.10 293 331 1.3E-11 T 23-04-2016 DC74_RS38065 992d8172a9abcdb59ae1a3ea973a666b 343 Gene3D G3DSA:3.90.25.10 194 237 1.3E-11 T 23-04-2016 DC74_RS38065 992d8172a9abcdb59ae1a3ea973a666b 343 PANTHER PTHR10366:SF466 12 326 5.3E-69 T 23-04-2016 DC74_RS38065 992d8172a9abcdb59ae1a3ea973a666b 343 Gene3D G3DSA:3.40.50.720 6 193 4.9E-51 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38065 992d8172a9abcdb59ae1a3ea973a666b 343 Gene3D G3DSA:3.40.50.720 238 275 4.9E-51 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38065 992d8172a9abcdb59ae1a3ea973a666b 343 SUPERFAMILY SSF51735 8 330 1.17E-71 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS12610 2c152c1820d401b13c17c07c952284d4 251 SUPERFAMILY SSF53335 11 204 4.07E-30 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS12610 2c152c1820d401b13c17c07c952284d4 251 Pfam PF08242 Methyltransferase domain 39 136 2.4E-14 T 23-04-2016 IPR013217 Methyltransferase type 12 DC74_RS12610 2c152c1820d401b13c17c07c952284d4 251 PANTHER PTHR10108:SF705 8 196 3.8E-20 T 23-04-2016 DC74_RS12610 2c152c1820d401b13c17c07c952284d4 251 Gene3D G3DSA:3.40.50.150 23 250 2.2E-28 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS12610 2c152c1820d401b13c17c07c952284d4 251 PANTHER PTHR10108 8 196 3.8E-20 T 23-04-2016 DC74_RS26785 35f98c1cffd608a6f6e3b62312f31849 302 Pfam PF03747 ADP-ribosylglycohydrolase 19 284 1.6E-45 T 23-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 DC74_RS26785 35f98c1cffd608a6f6e3b62312f31849 302 SUPERFAMILY SSF101478 12 301 5.23E-44 T 23-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 DC74_RS26785 35f98c1cffd608a6f6e3b62312f31849 302 PANTHER PTHR16222:SF12 11 302 1.3E-36 T 23-04-2016 DC74_RS26785 35f98c1cffd608a6f6e3b62312f31849 302 PANTHER PTHR16222 11 302 1.3E-36 T 23-04-2016 DC74_RS32560 aba9c9a2d81c7c8df1bb1f0a2678f494 359 Gene3D G3DSA:1.10.10.10 269 355 5.5E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32560 aba9c9a2d81c7c8df1bb1f0a2678f494 359 SUPERFAMILY SSF46785 267 349 1.53E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32560 aba9c9a2d81c7c8df1bb1f0a2678f494 359 Pfam PF12840 Helix-turn-helix domain 278 335 7.8E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32560 aba9c9a2d81c7c8df1bb1f0a2678f494 359 PANTHER PTHR33154 26 359 2.0E-94 T 23-04-2016 DC74_RS32560 aba9c9a2d81c7c8df1bb1f0a2678f494 359 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 279 294 4.8E-10 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS32560 aba9c9a2d81c7c8df1bb1f0a2678f494 359 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 311 326 4.8E-10 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS32560 aba9c9a2d81c7c8df1bb1f0a2678f494 359 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 326 341 4.8E-10 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS32560 aba9c9a2d81c7c8df1bb1f0a2678f494 359 SMART SM00418 277 355 2.0E-18 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS32560 aba9c9a2d81c7c8df1bb1f0a2678f494 359 PANTHER PTHR33154:SF11 26 359 2.0E-94 T 23-04-2016 DC74_RS34930 63afce1812f754e2310e2a87121911c0 283 PANTHER PTHR32243 6 283 4.5E-137 T 23-04-2016 DC74_RS34930 63afce1812f754e2310e2a87121911c0 283 Gene3D G3DSA:1.10.3720.10 7 270 5.2E-62 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS34930 63afce1812f754e2310e2a87121911c0 283 PANTHER PTHR32243:SF38 6 283 4.5E-137 T 23-04-2016 DC74_RS34930 63afce1812f754e2310e2a87121911c0 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 276 7.3E-21 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS34930 63afce1812f754e2310e2a87121911c0 283 SUPERFAMILY SSF161098 10 283 1.23E-66 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS23515 b3124b0468bbca5f696a2254a90043f1 339 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 33 273 2.4E-55 T 23-04-2016 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related DC74_RS05715 f8a8d540e3312e369a4964f684debdb6 66 SUPERFAMILY SSF160582 2 62 7.59E-25 T 23-04-2016 DC74_RS05715 f8a8d540e3312e369a4964f684debdb6 66 Pfam PF03621 MbtH-like protein 2 52 2.4E-24 T 23-04-2016 IPR005153 MbtH-like protein DC74_RS05715 f8a8d540e3312e369a4964f684debdb6 66 Gene3D G3DSA:3.90.820.10 10 61 4.7E-23 T 23-04-2016 DC74_RS05715 f8a8d540e3312e369a4964f684debdb6 66 PANTHER PTHR38444:SF1 1 61 1.6E-26 T 23-04-2016 DC74_RS05715 f8a8d540e3312e369a4964f684debdb6 66 SMART SM00923 3 53 2.2E-25 T 23-04-2016 IPR005153 MbtH-like protein DC74_RS05715 f8a8d540e3312e369a4964f684debdb6 66 PANTHER PTHR38444 1 61 1.6E-26 T 23-04-2016 DC74_RS00875 a7a9ae188823f5ca9d5918a31436a7fe 438 PANTHER PTHR24423 159 438 7.1E-42 T 23-04-2016 DC74_RS00875 a7a9ae188823f5ca9d5918a31436a7fe 438 SMART SM00304 165 219 8.7E-7 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS00875 a7a9ae188823f5ca9d5918a31436a7fe 438 SUPERFAMILY SSF158472 168 215 2.48E-5 T 23-04-2016 DC74_RS00875 a7a9ae188823f5ca9d5918a31436a7fe 438 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 428 6.0E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS00875 a7a9ae188823f5ca9d5918a31436a7fe 438 SUPERFAMILY SSF55874 267 429 4.32E-25 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS00875 a7a9ae188823f5ca9d5918a31436a7fe 438 Gene3D G3DSA:1.10.287.130 210 265 1.8E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS00875 a7a9ae188823f5ca9d5918a31436a7fe 438 Gene3D G3DSA:3.30.565.10 266 430 2.0E-24 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS00875 a7a9ae188823f5ca9d5918a31436a7fe 438 Pfam PF00512 His Kinase A (phospho-acceptor) domain 221 278 2.5E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS00875 a7a9ae188823f5ca9d5918a31436a7fe 438 Pfam PF00672 HAMP domain 146 216 3.0E-11 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 DC74_RS00875 a7a9ae188823f5ca9d5918a31436a7fe 438 SMART SM00387 321 431 4.1E-16 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS00875 a7a9ae188823f5ca9d5918a31436a7fe 438 SUPERFAMILY SSF47384 207 278 3.14E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS00875 a7a9ae188823f5ca9d5918a31436a7fe 438 SMART SM00388 220 278 4.7E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS13995 77b251b84ece7d0d750580605530c939 388 Pfam PF06259 Alpha/beta hydrolase 158 334 1.9E-47 T 23-04-2016 IPR010427 Protein of unknown function DUF1023 DC74_RS13575 1c4a9a350f78127453ad426e480cd882 297 SUPERFAMILY SSF54637 15 163 3.26E-32 T 23-04-2016 IPR029069 HotDog domain DC74_RS13575 1c4a9a350f78127453ad426e480cd882 297 Gene3D G3DSA:3.10.129.10 152 292 2.6E-42 T 23-04-2016 IPR029069 HotDog domain DC74_RS13575 1c4a9a350f78127453ad426e480cd882 297 Pfam PF01575 MaoC like domain 169 278 2.0E-30 T 23-04-2016 IPR002539 MaoC-like domain DC74_RS13575 1c4a9a350f78127453ad426e480cd882 297 Pfam PF13452 N-terminal half of MaoC dehydratase 18 139 8.4E-12 T 23-04-2016 DC74_RS13575 1c4a9a350f78127453ad426e480cd882 297 Gene3D G3DSA:3.10.129.10 1 151 1.4E-43 T 23-04-2016 IPR029069 HotDog domain DC74_RS13575 1c4a9a350f78127453ad426e480cd882 297 PANTHER PTHR13078 1 295 9.9E-104 T 23-04-2016 DC74_RS13575 1c4a9a350f78127453ad426e480cd882 297 PANTHER PTHR13078:SF5 1 295 9.9E-104 T 23-04-2016 DC74_RS13575 1c4a9a350f78127453ad426e480cd882 297 SUPERFAMILY SSF54637 167 290 4.97E-32 T 23-04-2016 IPR029069 HotDog domain DC74_RS12545 e2372c44b1326e809102f35cf158a9a2 450 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 367 391 - T 23-04-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 DC74_RS12545 e2372c44b1326e809102f35cf158a9a2 450 PANTHER PTHR30474 29 426 2.7E-141 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 DC74_RS12545 e2372c44b1326e809102f35cf158a9a2 450 Pfam PF01098 Cell cycle protein 54 407 9.9E-95 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 DC74_RS12545 e2372c44b1326e809102f35cf158a9a2 450 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 52 408 2.4E-113 T 23-04-2016 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 DC74_RS12545 e2372c44b1326e809102f35cf158a9a2 450 PANTHER PTHR30474:SF2 29 426 2.7E-141 T 23-04-2016 DC74_RS22410 2d1fde33620ccdd72840cfe583fd874e 574 Pfam PF06738 Putative threonine/serine exporter 152 393 4.9E-60 T 23-04-2016 IPR010619 Putative threonine/serine exporter DC74_RS22410 2d1fde33620ccdd72840cfe583fd874e 574 Pfam PF12821 Threonine/Serine exporter, ThrE 419 544 1.4E-18 T 23-04-2016 IPR024528 Threonine/Serine exporter, ThrE DC74_RS22410 2d1fde33620ccdd72840cfe583fd874e 574 PANTHER PTHR34390:SF1 404 574 8.4E-170 T 23-04-2016 DC74_RS22410 2d1fde33620ccdd72840cfe583fd874e 574 PANTHER PTHR34390:SF1 96 261 8.4E-170 T 23-04-2016 DC74_RS22410 2d1fde33620ccdd72840cfe583fd874e 574 PANTHER PTHR34390 96 261 8.4E-170 T 23-04-2016 DC74_RS22410 2d1fde33620ccdd72840cfe583fd874e 574 PANTHER PTHR34390 404 574 8.4E-170 T 23-04-2016 DC74_RS10475 241c6265e0e4390b709e21f38f9cc07f 330 Gene3D G3DSA:1.20.58.340 138 252 6.4E-39 T 23-04-2016 DC74_RS10475 241c6265e0e4390b709e21f38f9cc07f 330 SUPERFAMILY SSF143865 4 262 1.96E-65 T 23-04-2016 DC74_RS10475 241c6265e0e4390b709e21f38f9cc07f 330 PANTHER PTHR21535 37 330 2.0E-51 T 23-04-2016 DC74_RS10475 241c6265e0e4390b709e21f38f9cc07f 330 Gene3D G3DSA:1.20.58.340 254 330 4.4E-25 T 23-04-2016 DC74_RS10475 241c6265e0e4390b709e21f38f9cc07f 330 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 28 330 2.8E-65 T 23-04-2016 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 DC74_RS10475 241c6265e0e4390b709e21f38f9cc07f 330 Gene3D G3DSA:3.30.460.20 4 137 2.2E-42 T 23-04-2016 DC74_RS10475 241c6265e0e4390b709e21f38f9cc07f 330 SUPERFAMILY SSF144083 265 327 3.79E-19 T 23-04-2016 DC74_RS10475 241c6265e0e4390b709e21f38f9cc07f 330 Pfam PF01544 CorA-like Mg2+ transporter protein 36 326 2.2E-65 T 23-04-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 DC74_RS02005 e14a45945a04c7fec1223f81850e2c96 388 Gene3D G3DSA:3.40.50.1240 178 372 3.8E-36 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS02005 e14a45945a04c7fec1223f81850e2c96 388 SMART SM00855 179 333 3.0E-4 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS02005 e14a45945a04c7fec1223f81850e2c96 388 SUPERFAMILY SSF53254 180 369 5.57E-36 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS02005 e14a45945a04c7fec1223f81850e2c96 388 PANTHER PTHR23029 180 365 7.7E-26 T 23-04-2016 DC74_RS02005 e14a45945a04c7fec1223f81850e2c96 388 Gene3D G3DSA:3.40.50.300 6 138 3.0E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02005 e14a45945a04c7fec1223f81850e2c96 388 SUPERFAMILY SSF52540 6 162 7.68E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02005 e14a45945a04c7fec1223f81850e2c96 388 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 180 371 5.3E-36 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS01655 310cba4de9bbba4e78e6595feb3af4d6 409 Pfam PF07730 Histidine kinase 208 272 8.6E-16 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS01655 310cba4de9bbba4e78e6595feb3af4d6 409 PANTHER PTHR24421:SF26 113 404 1.9E-53 T 23-04-2016 DC74_RS01655 310cba4de9bbba4e78e6595feb3af4d6 409 PANTHER PTHR24421 113 404 1.9E-53 T 23-04-2016 DC74_RS01655 310cba4de9bbba4e78e6595feb3af4d6 409 SUPERFAMILY SSF55874 287 404 2.07E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS26415 b3be367328dedb1ec3a786dca521d544 195 SUPERFAMILY SSF52980 23 187 4.24E-18 T 23-04-2016 IPR011335 Restriction endonuclease type II-like DC74_RS26415 b3be367328dedb1ec3a786dca521d544 195 Pfam PF05685 Putative restriction endonuclease 23 186 1.1E-26 T 23-04-2016 IPR008538 Domain of unknown function DUF820 DC74_RS26415 b3be367328dedb1ec3a786dca521d544 195 Gene3D G3DSA:3.90.1570.10 23 163 7.3E-15 T 23-04-2016 IPR012296 Nuclease, putative, TT1808 DC74_RS26415 b3be367328dedb1ec3a786dca521d544 195 PANTHER PTHR35400:SF1 11 195 8.3E-47 T 23-04-2016 DC74_RS26415 b3be367328dedb1ec3a786dca521d544 195 PANTHER PTHR35400 11 195 8.3E-47 T 23-04-2016 DC74_RS01460 6fff33aea3553121a90b139726aee78a 192 Gene3D G3DSA:2.30.180.10 60 188 1.3E-32 T 23-04-2016 IPR000782 FAS1 domain DC74_RS01460 6fff33aea3553121a90b139726aee78a 192 Pfam PF02469 Fasciclin domain 70 190 6.8E-32 T 23-04-2016 IPR000782 FAS1 domain DC74_RS01460 6fff33aea3553121a90b139726aee78a 192 SUPERFAMILY SSF82153 51 191 7.85E-36 T 23-04-2016 IPR000782 FAS1 domain DC74_RS01460 6fff33aea3553121a90b139726aee78a 192 SMART SM00554 94 191 5.1E-30 T 23-04-2016 IPR000782 FAS1 domain DC74_RS01460 6fff33aea3553121a90b139726aee78a 192 PANTHER PTHR10900 43 191 1.3E-37 T 23-04-2016 DC74_RS27695 9ec50afc5bb97f63b5cb09d4e41518df 332 PANTHER PTHR21371 2 329 5.7E-192 T 23-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS27695 9ec50afc5bb97f63b5cb09d4e41518df 332 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 1.8E-132 T 23-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS27695 9ec50afc5bb97f63b5cb09d4e41518df 332 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 8.3E-65 T 23-04-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS27695 9ec50afc5bb97f63b5cb09d4e41518df 332 SUPERFAMILY SSF48179 184 329 8.67E-69 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS27695 9ec50afc5bb97f63b5cb09d4e41518df 332 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 2 329 44.613 T 23-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS27695 9ec50afc5bb97f63b5cb09d4e41518df 332 SUPERFAMILY SSF51735 3 183 1.51E-72 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27695 9ec50afc5bb97f63b5cb09d4e41518df 332 Gene3D G3DSA:1.10.1040.10 30 326 2.5E-112 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS27695 9ec50afc5bb97f63b5cb09d4e41518df 332 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 3.0E-76 T 23-04-2016 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 DC74_RS20695 e3a336a116c530f189594bbe7bf219b1 45 Pfam PF00468 Ribosomal protein L34 3 45 9.6E-20 T 23-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20695 e3a336a116c530f189594bbe7bf219b1 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 23-04-2016 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20695 e3a336a116c530f189594bbe7bf219b1 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.594 T 23-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20695 e3a336a116c530f189594bbe7bf219b1 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 40 3.0E-13 T 23-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20695 e3a336a116c530f189594bbe7bf219b1 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 1.3E-19 T 23-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20695 e3a336a116c530f189594bbe7bf219b1 45 PANTHER PTHR14503 3 45 4.2E-15 T 23-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS31335 3b246c0a3790575a056ae38c2fa22637 126 PANTHER PTHR35568 1 126 1.4E-31 T 23-04-2016 DC74_RS31335 3b246c0a3790575a056ae38c2fa22637 126 Pfam PF13309 HTH domain 56 117 7.9E-20 T 23-04-2016 DC74_RS23345 113dc590a28172095a5196e9cb65dd64 242 PANTHER PTHR22572 11 240 1.3E-78 T 23-04-2016 DC74_RS23345 113dc590a28172095a5196e9cb65dd64 242 PANTHER PTHR22572:SF107 11 240 1.3E-78 T 23-04-2016 DC74_RS23345 113dc590a28172095a5196e9cb65dd64 242 Gene3D G3DSA:3.90.550.10 9 240 1.0E-56 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS23345 113dc590a28172095a5196e9cb65dd64 242 Pfam PF00483 Nucleotidyl transferase 12 238 1.5E-24 T 23-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 DC74_RS23345 113dc590a28172095a5196e9cb65dd64 242 SUPERFAMILY SSF53448 10 237 1.13E-54 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS06255 b130c2485fd05beac9854612f433b970 306 PANTHER PTHR40057 1 305 1.5E-45 T 23-04-2016 DC74_RS06255 b130c2485fd05beac9854612f433b970 306 SUPERFAMILY SSF54909 93 184 6.0E-20 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS06255 b130c2485fd05beac9854612f433b970 306 SUPERFAMILY SSF54909 1 87 1.49E-17 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS06255 b130c2485fd05beac9854612f433b970 306 PANTHER PTHR40057:SF1 1 305 1.5E-45 T 23-04-2016 DC74_RS06255 b130c2485fd05beac9854612f433b970 306 Gene3D G3DSA:3.30.70.900 5 85 5.8E-11 T 23-04-2016 DC74_RS06255 b130c2485fd05beac9854612f433b970 306 Gene3D G3DSA:3.30.70.900 98 177 1.1E-10 T 23-04-2016 DC74_RS06255 b130c2485fd05beac9854612f433b970 306 Pfam PF03992 Antibiotic biosynthesis monooxygenase 98 167 4.2E-6 T 23-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain DC74_RS25245 41fc50d362183790916bf8357b95a251 292 PANTHER PTHR30294:SF24 22 288 7.3E-104 T 23-04-2016 DC74_RS25245 41fc50d362183790916bf8357b95a251 292 PIRSF PIRSF006648 3 292 4.9E-75 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS25245 41fc50d362183790916bf8357b95a251 292 PANTHER PTHR30294 22 288 7.3E-104 T 23-04-2016 DC74_RS25245 41fc50d362183790916bf8357b95a251 292 Pfam PF01061 ABC-2 type transporter 30 243 1.0E-29 T 23-04-2016 IPR013525 ABC-2 type transporter GO:0016020 DC74_RS39030 5e88edbae40bae04ded158efb12e111e 122 PANTHER PTHR30007:SF0 2 104 3.9E-16 T 23-04-2016 DC74_RS39030 5e88edbae40bae04ded158efb12e111e 122 Pfam PF01609 Transposase DDE domain 7 89 6.8E-8 T 23-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 DC74_RS39030 5e88edbae40bae04ded158efb12e111e 122 PANTHER PTHR30007 2 104 3.9E-16 T 23-04-2016 DC74_RS36615 af9c86b4fdf19a47e9cd4d414a03253f 124 Pfam PF04237 YjbR 22 109 3.5E-16 T 23-04-2016 IPR007351 Uncharacterised protein YjbR DC74_RS36615 af9c86b4fdf19a47e9cd4d414a03253f 124 SUPERFAMILY SSF142906 13 118 5.75E-19 T 23-04-2016 DC74_RS04615 425761e05d7fc8ae1a9267266ae77e0f 260 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS04615 425761e05d7fc8ae1a9267266ae77e0f 260 Gene3D G3DSA:3.40.50.300 21 237 1.3E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04615 425761e05d7fc8ae1a9267266ae77e0f 260 PANTHER PTHR24220 20 258 1.4E-161 T 23-04-2016 DC74_RS04615 425761e05d7fc8ae1a9267266ae77e0f 260 SMART SM00382 47 233 6.4E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS04615 425761e05d7fc8ae1a9267266ae77e0f 260 SUPERFAMILY SSF52540 20 238 5.57E-69 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04615 425761e05d7fc8ae1a9267266ae77e0f 260 PANTHER PTHR24220:SF484 20 258 1.4E-161 T 23-04-2016 DC74_RS04615 425761e05d7fc8ae1a9267266ae77e0f 260 Pfam PF00005 ABC transporter 38 184 5.4E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS09150 4d4c37691fbfe0fc9c81702a2298328d 331 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 76 321 4.7E-8 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS09150 4d4c37691fbfe0fc9c81702a2298328d 331 SUPERFAMILY SSF52266 74 151 1.44E-15 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS09150 4d4c37691fbfe0fc9c81702a2298328d 331 SUPERFAMILY SSF52266 207 238 1.44E-15 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS09150 4d4c37691fbfe0fc9c81702a2298328d 331 SUPERFAMILY SSF52266 265 331 1.44E-15 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS09150 4d4c37691fbfe0fc9c81702a2298328d 331 Gene3D G3DSA:3.40.50.1110 74 157 1.5E-9 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS09150 4d4c37691fbfe0fc9c81702a2298328d 331 Gene3D G3DSA:3.40.50.1110 199 331 1.5E-9 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS36325 67a0a9fbeca63eb666a2bf2d0b9d21c8 390 Gene3D G3DSA:1.10.540.10 1 122 1.9E-21 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS36325 67a0a9fbeca63eb666a2bf2d0b9d21c8 390 PANTHER PTHR10909:SF229 1 389 1.1E-128 T 23-04-2016 DC74_RS36325 67a0a9fbeca63eb666a2bf2d0b9d21c8 390 SUPERFAMILY SSF47203 231 384 3.22E-21 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS36325 67a0a9fbeca63eb666a2bf2d0b9d21c8 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 382 3.2E-21 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS36325 67a0a9fbeca63eb666a2bf2d0b9d21c8 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 219 1.5E-17 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS36325 67a0a9fbeca63eb666a2bf2d0b9d21c8 390 Gene3D G3DSA:2.40.110.10 123 221 2.9E-26 T 23-04-2016 DC74_RS36325 67a0a9fbeca63eb666a2bf2d0b9d21c8 390 SUPERFAMILY SSF56645 2 242 1.7E-56 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS36325 67a0a9fbeca63eb666a2bf2d0b9d21c8 390 Gene3D G3DSA:1.20.140.10 222 387 9.4E-31 T 23-04-2016 DC74_RS36325 67a0a9fbeca63eb666a2bf2d0b9d21c8 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 120 3.4E-15 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS36325 67a0a9fbeca63eb666a2bf2d0b9d21c8 390 PANTHER PTHR10909 1 389 1.1E-128 T 23-04-2016 DC74_RS03840 a4ac05c9e1e2355f538b02926590ad26 405 PANTHER PTHR23542 8 402 1.0E-46 T 23-04-2016 DC74_RS03840 a4ac05c9e1e2355f538b02926590ad26 405 SUPERFAMILY SSF103473 16 403 1.57E-27 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS03840 a4ac05c9e1e2355f538b02926590ad26 405 PANTHER PTHR23542:SF1 8 402 1.0E-46 T 23-04-2016 DC74_RS03840 a4ac05c9e1e2355f538b02926590ad26 405 Gene3D G3DSA:1.20.1250.20 243 404 1.0E-10 T 23-04-2016 DC74_RS03840 a4ac05c9e1e2355f538b02926590ad26 405 Gene3D G3DSA:1.20.1250.20 23 195 4.0E-12 T 23-04-2016 DC74_RS03840 a4ac05c9e1e2355f538b02926590ad26 405 Pfam PF07690 Major Facilitator Superfamily 24 310 4.1E-12 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS11975 dafeb9b7314ec980445977e56cf7a718 313 SUPERFAMILY SSF50129 2 128 9.28E-29 T 23-04-2016 IPR011032 GroES-like DC74_RS11975 dafeb9b7314ec980445977e56cf7a718 313 Gene3D G3DSA:3.90.180.10 2 136 6.6E-34 T 23-04-2016 IPR011032 GroES-like DC74_RS11975 dafeb9b7314ec980445977e56cf7a718 313 Gene3D G3DSA:3.40.50.720 137 249 9.2E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11975 dafeb9b7314ec980445977e56cf7a718 313 PANTHER PTHR11695:SF605 15 311 1.1E-73 T 23-04-2016 DC74_RS11975 dafeb9b7314ec980445977e56cf7a718 313 SUPERFAMILY SSF51735 101 276 6.1E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11975 dafeb9b7314ec980445977e56cf7a718 313 SMART SM00829 10 309 2.5E-12 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS11975 dafeb9b7314ec980445977e56cf7a718 313 PANTHER PTHR11695 15 311 1.1E-73 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS11975 dafeb9b7314ec980445977e56cf7a718 313 Pfam PF00107 Zinc-binding dehydrogenase 140 258 3.6E-29 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS25015 be84730bb334ea0615b457222a8bf6ea 286 Gene3D G3DSA:3.40.605.10 6 254 9.1E-54 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS25015 be84730bb334ea0615b457222a8bf6ea 286 Pfam PF00171 Aldehyde dehydrogenase family 23 254 5.0E-40 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS25015 be84730bb334ea0615b457222a8bf6ea 286 SUPERFAMILY SSF53720 6 255 3.01E-44 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS25015 be84730bb334ea0615b457222a8bf6ea 286 PANTHER PTHR11699 1 259 4.2E-106 T 23-04-2016 DC74_RS25015 be84730bb334ea0615b457222a8bf6ea 286 PANTHER PTHR11699:SF165 1 259 4.2E-106 T 23-04-2016 DC74_RS35110 580f409a2e09761bc094fc8685c1f152 126 PANTHER PTHR36221 12 124 3.0E-29 T 23-04-2016 DC74_RS35110 580f409a2e09761bc094fc8685c1f152 126 Pfam PF05331 Protein of unknown function (DUF742) 12 123 4.6E-31 T 23-04-2016 IPR007995 Protein of unknown function DUF742 DC74_RS12460 67562c817f52e5a5af9c936efd55abd3 306 Gene3D G3DSA:3.40.30.10 84 261 2.2E-24 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS12460 67562c817f52e5a5af9c936efd55abd3 306 PANTHER PTHR13887 12 272 3.5E-15 T 23-04-2016 DC74_RS12460 67562c817f52e5a5af9c936efd55abd3 306 SUPERFAMILY SSF52833 81 246 4.64E-19 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS12460 67562c817f52e5a5af9c936efd55abd3 306 PANTHER PTHR13887:SF14 12 272 3.5E-15 T 23-04-2016 DC74_RS12460 67562c817f52e5a5af9c936efd55abd3 306 Pfam PF13462 Thioredoxin 81 246 5.7E-35 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS36035 3ecd155c1223150f2d547797dd1f8818 164 SUPERFAMILY SSF46785 20 150 2.01E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36035 3ecd155c1223150f2d547797dd1f8818 164 PANTHER PTHR33164 1 163 6.7E-21 T 23-04-2016 DC74_RS36035 3ecd155c1223150f2d547797dd1f8818 164 Gene3D G3DSA:1.10.10.10 12 149 2.8E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS36035 3ecd155c1223150f2d547797dd1f8818 164 Pfam PF01047 MarR family 51 103 3.1E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS36035 3ecd155c1223150f2d547797dd1f8818 164 SMART SM00347 39 139 5.9E-15 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS36035 3ecd155c1223150f2d547797dd1f8818 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 3.3E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS36035 3ecd155c1223150f2d547797dd1f8818 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 3.3E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS36035 3ecd155c1223150f2d547797dd1f8818 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 3.3E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS38120 f08e92cf43bb15604ec63730e79c2115 215 SUPERFAMILY SSF52540 6 198 5.19E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38120 f08e92cf43bb15604ec63730e79c2115 215 Gene3D G3DSA:3.40.50.300 6 199 7.5E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14025 19f519f294c6036ce60c0435b2418c67 394 Pfam PF13556 PucR C-terminal helix-turn-helix domain 326 383 8.7E-20 T 23-04-2016 IPR025736 PucR C-terminal helix-turn-helix domain DC74_RS14025 19f519f294c6036ce60c0435b2418c67 394 PANTHER PTHR33744:SF2 31 394 1.5E-193 T 23-04-2016 DC74_RS14025 19f519f294c6036ce60c0435b2418c67 394 PANTHER PTHR33744 31 394 1.5E-193 T 23-04-2016 DC74_RS19460 b2b37db12292d7cdb5d41a17712954ce 289 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 38 228 5.0E-15 T 23-04-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 DC74_RS19460 b2b37db12292d7cdb5d41a17712954ce 289 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 38 239 1.1E-53 T 23-04-2016 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial DC74_RS19460 b2b37db12292d7cdb5d41a17712954ce 289 SUPERFAMILY SSF56784 37 256 6.4E-29 T 23-04-2016 IPR023214 HAD-like domain DC74_RS19460 b2b37db12292d7cdb5d41a17712954ce 289 PANTHER PTHR10000:SF30 69 267 2.2E-101 T 23-04-2016 DC74_RS19460 b2b37db12292d7cdb5d41a17712954ce 289 PANTHER PTHR10000 69 267 2.2E-101 T 23-04-2016 DC74_RS19460 b2b37db12292d7cdb5d41a17712954ce 289 Pfam PF12710 haloacid dehalogenase-like hydrolase 39 225 6.6E-27 T 23-04-2016 DC74_RS19460 b2b37db12292d7cdb5d41a17712954ce 289 Gene3D G3DSA:3.40.50.1000 111 255 9.7E-48 T 23-04-2016 IPR023214 HAD-like domain DC74_RS34605 73b36fea5f97dc261fc584fbe523f0f3 569 Pfam PF07730 Histidine kinase 172 236 2.6E-12 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS34605 73b36fea5f97dc261fc584fbe523f0f3 569 PANTHER PTHR24421 32 404 6.6E-66 T 23-04-2016 DC74_RS34605 73b36fea5f97dc261fc584fbe523f0f3 569 PANTHER PTHR24421:SF26 32 404 6.6E-66 T 23-04-2016 DC74_RS34605 73b36fea5f97dc261fc584fbe523f0f3 569 SUPERFAMILY SSF55874 273 388 8.82E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS21185 84c5499bae833dceace558ca17e750fc 675 SUPERFAMILY SSF81296 31 129 8.4E-22 T 23-04-2016 IPR014756 Immunoglobulin E-set DC74_RS21185 84c5499bae833dceace558ca17e750fc 675 Gene3D G3DSA:2.60.40.1220 31 129 5.0E-26 T 23-04-2016 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like DC74_RS21185 84c5499bae833dceace558ca17e750fc 675 Pfam PF04234 CopC domain 32 129 6.1E-23 T 23-04-2016 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 DC74_RS21185 84c5499bae833dceace558ca17e750fc 675 Pfam PF05425 Copper resistance protein D 364 441 1.7E-18 T 23-04-2016 IPR008457 Copper resistance protein D GO:0016021 DC74_RS21185 84c5499bae833dceace558ca17e750fc 675 PANTHER PTHR34820:SF2 513 675 1.0E-171 T 23-04-2016 DC74_RS21185 84c5499bae833dceace558ca17e750fc 675 PANTHER PTHR34820:SF2 291 439 1.0E-171 T 23-04-2016 DC74_RS21185 84c5499bae833dceace558ca17e750fc 675 PANTHER PTHR34820:SF2 7 260 1.0E-171 T 23-04-2016 DC74_RS21185 84c5499bae833dceace558ca17e750fc 675 PANTHER PTHR34820 513 675 1.0E-171 T 23-04-2016 DC74_RS21185 84c5499bae833dceace558ca17e750fc 675 PANTHER PTHR34820 291 439 1.0E-171 T 23-04-2016 DC74_RS21185 84c5499bae833dceace558ca17e750fc 675 PANTHER PTHR34820 7 260 1.0E-171 T 23-04-2016 DC74_RS20315 090826e4552d14426f2bd874ebcace2f 176 SUPERFAMILY SSF54518 8 163 1.05E-30 T 23-04-2016 IPR025659 Tubby C-terminal-like domain DC74_RS20315 090826e4552d14426f2bd874ebcace2f 176 PANTHER PTHR31087 21 176 2.0E-25 T 23-04-2016 DC74_RS20315 090826e4552d14426f2bd874ebcace2f 176 PANTHER PTHR31087:SF11 21 176 2.0E-25 T 23-04-2016 DC74_RS20315 090826e4552d14426f2bd874ebcace2f 176 Pfam PF04525 LURP-one-related 25 163 1.7E-23 T 23-04-2016 IPR007612 LURP1-related protein domain DC74_RS16930 1511ecf4744fee4ae88cab12c2ea4708 354 PANTHER PTHR38480:SF1 1 311 2.4E-60 T 23-04-2016 DC74_RS16930 1511ecf4744fee4ae88cab12c2ea4708 354 Pfam PF06271 RDD family 17 144 1.0E-14 T 23-04-2016 IPR010432 RDD DC74_RS16930 1511ecf4744fee4ae88cab12c2ea4708 354 PANTHER PTHR38480 1 311 2.4E-60 T 23-04-2016 DC74_RS17970 aa836382efefd7bf8cb02b68b251259f 282 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 1 146 4.5E-20 T 23-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 DC74_RS17970 aa836382efefd7bf8cb02b68b251259f 282 Gene3D G3DSA:3.40.50.720 1 149 2.9E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17970 aa836382efefd7bf8cb02b68b251259f 282 PIRSF PIRSF000103 1 282 2.0E-32 T 23-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 DC74_RS17970 aa836382efefd7bf8cb02b68b251259f 282 SUPERFAMILY SSF51735 1 149 9.55E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17970 aa836382efefd7bf8cb02b68b251259f 282 PANTHER PTHR22981:SF76 2 275 1.8E-57 T 23-04-2016 DC74_RS17970 aa836382efefd7bf8cb02b68b251259f 282 PANTHER PTHR22981 2 275 1.8E-57 T 23-04-2016 DC74_RS13800 bbf6216068820d4b8a39c4ca2456a310 248 PANTHER PTHR30028 11 238 2.6E-28 T 23-04-2016 DC74_RS13800 bbf6216068820d4b8a39c4ca2456a310 248 PANTHER PTHR30028:SF0 11 238 2.6E-28 T 23-04-2016 IPR005226 UPF0014 family DC74_RS13800 bbf6216068820d4b8a39c4ca2456a310 248 Pfam PF03649 Uncharacterised protein family (UPF0014) 12 238 2.6E-45 T 23-04-2016 IPR005226 UPF0014 family DC74_RS09295 34031f575512ed0a38bf7c4fe51a5bfb 268 PANTHER PTHR23088:SF27 1 268 2.3E-72 T 23-04-2016 DC74_RS09295 34031f575512ed0a38bf7c4fe51a5bfb 268 PANTHER PTHR23088 1 268 2.3E-72 T 23-04-2016 DC74_RS09295 34031f575512ed0a38bf7c4fe51a5bfb 268 Gene3D G3DSA:3.60.110.10 2 268 7.7E-78 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS09295 34031f575512ed0a38bf7c4fe51a5bfb 268 Pfam PF00795 Carbon-nitrogen hydrolase 7 250 7.1E-49 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS09295 34031f575512ed0a38bf7c4fe51a5bfb 268 SUPERFAMILY SSF56317 1 267 1.7E-73 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS09295 34031f575512ed0a38bf7c4fe51a5bfb 268 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 146 166 - T 23-04-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site DC74_RS32940 69bec7085d6397b700d807555591ca4f 186 PANTHER PTHR30328 1 180 1.3E-38 T 23-04-2016 DC74_RS32940 69bec7085d6397b700d807555591ca4f 186 Gene3D G3DSA:1.10.357.10 46 181 1.3E-43 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS32940 69bec7085d6397b700d807555591ca4f 186 SUPERFAMILY SSF46689 1 70 4.99E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS32940 69bec7085d6397b700d807555591ca4f 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 46 1.8E-18 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS32940 69bec7085d6397b700d807555591ca4f 186 Gene3D G3DSA:1.10.10.60 1 45 4.2E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS32940 69bec7085d6397b700d807555591ca4f 186 SUPERFAMILY SSF48498 68 181 1.93E-20 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS32940 69bec7085d6397b700d807555591ca4f 186 PANTHER PTHR30328:SF25 1 180 1.3E-38 T 23-04-2016 DC74_RS31780 56e424a7026d7f64957cce15b67fbeb3 273 Gene3D G3DSA:1.10.357.10 80 220 5.5E-26 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS31780 56e424a7026d7f64957cce15b67fbeb3 273 PANTHER PTHR30055 20 262 7.7E-74 T 23-04-2016 DC74_RS31780 56e424a7026d7f64957cce15b67fbeb3 273 PANTHER PTHR30055:SF80 20 262 7.7E-74 T 23-04-2016 DC74_RS31780 56e424a7026d7f64957cce15b67fbeb3 273 ProSitePatterns PS01081 TetR-type HTH domain signature. 52 83 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS31780 56e424a7026d7f64957cce15b67fbeb3 273 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 61 84 3.2E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS31780 56e424a7026d7f64957cce15b67fbeb3 273 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 53 3.2E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS31780 56e424a7026d7f64957cce15b67fbeb3 273 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 81 2.1E-17 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS31780 56e424a7026d7f64957cce15b67fbeb3 273 SUPERFAMILY SSF46689 28 89 2.6E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS31780 56e424a7026d7f64957cce15b67fbeb3 273 Gene3D G3DSA:1.10.10.60 36 79 2.6E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS31825 8331d69dc0506f0eb7cd6ac70174a1a2 251 PANTHER PTHR11638 88 232 1.6E-62 T 23-04-2016 DC74_RS31825 8331d69dc0506f0eb7cd6ac70174a1a2 251 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 189 233 5.6E-13 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS31825 8331d69dc0506f0eb7cd6ac70174a1a2 251 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 112 163 7.9E-13 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS31825 8331d69dc0506f0eb7cd6ac70174a1a2 251 PANTHER PTHR11638:SF83 88 232 1.6E-62 T 23-04-2016 DC74_RS31825 8331d69dc0506f0eb7cd6ac70174a1a2 251 Gene3D G3DSA:1.10.1780.10 98 232 1.1E-35 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS31825 8331d69dc0506f0eb7cd6ac70174a1a2 251 SUPERFAMILY SSF81923 100 233 4.55E-26 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS18910 436e53700c9cd08c63383a7d5fd3fddc 196 PANTHER PTHR33269:SF4 11 176 8.1E-43 T 23-04-2016 DC74_RS18910 436e53700c9cd08c63383a7d5fd3fddc 196 PANTHER PTHR33269 11 176 8.1E-43 T 23-04-2016 DC74_RS18910 436e53700c9cd08c63383a7d5fd3fddc 196 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 31 173 1.2E-30 T 23-04-2016 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 DC74_RS04570 2ee91fc39a1fcd3bb5ab0165975cae15 516 PANTHER PTHR30365 407 509 2.9E-193 T 23-04-2016 DC74_RS04570 2ee91fc39a1fcd3bb5ab0165975cae15 516 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 11 490 5.2E-171 T 23-04-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 DC74_RS04570 2ee91fc39a1fcd3bb5ab0165975cae15 516 PANTHER PTHR30365:SF0 407 509 2.9E-193 T 23-04-2016 DC74_RS04570 2ee91fc39a1fcd3bb5ab0165975cae15 516 PANTHER PTHR30365:SF0 1 377 2.9E-193 T 23-04-2016 DC74_RS04570 2ee91fc39a1fcd3bb5ab0165975cae15 516 PANTHER PTHR30365 1 377 2.9E-193 T 23-04-2016 DC74_RS22070 64b9634953665ca84873653e6a197690 309 Pfam PF12697 Alpha/beta hydrolase family 44 294 4.6E-22 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS22070 64b9634953665ca84873653e6a197690 309 PANTHER PTHR10992 9 304 4.7E-77 T 23-04-2016 DC74_RS22070 64b9634953665ca84873653e6a197690 309 PRINTS PR00412 Epoxide hydrolase signature 48 66 5.4E-23 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS22070 64b9634953665ca84873653e6a197690 309 PRINTS PR00412 Epoxide hydrolase signature 245 261 5.4E-23 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS22070 64b9634953665ca84873653e6a197690 309 PRINTS PR00412 Epoxide hydrolase signature 126 139 5.4E-23 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS22070 64b9634953665ca84873653e6a197690 309 PRINTS PR00412 Epoxide hydrolase signature 279 301 5.4E-23 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS22070 64b9634953665ca84873653e6a197690 309 PRINTS PR00412 Epoxide hydrolase signature 112 125 5.4E-23 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS22070 64b9634953665ca84873653e6a197690 309 PRINTS PR00412 Epoxide hydrolase signature 68 83 5.4E-23 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS22070 64b9634953665ca84873653e6a197690 309 SUPERFAMILY SSF53474 20 304 9.54E-68 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS22070 64b9634953665ca84873653e6a197690 309 PANTHER PTHR10992:SF107 9 304 4.7E-77 T 23-04-2016 DC74_RS22070 64b9634953665ca84873653e6a197690 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 126 139 1.0E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS22070 64b9634953665ca84873653e6a197690 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 1.0E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS22070 64b9634953665ca84873653e6a197690 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 68 83 1.0E-5 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS22070 64b9634953665ca84873653e6a197690 309 Gene3D G3DSA:3.40.50.1820 19 304 1.4E-70 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS26495 5bb37aa26eab33ffe2137f1ef0e12659 137 PANTHER PTHR35526 1 137 1.2E-35 T 23-04-2016 DC74_RS26495 5bb37aa26eab33ffe2137f1ef0e12659 137 PANTHER PTHR35526:SF1 1 137 1.2E-35 T 23-04-2016 DC74_RS17905 e2a54ce172e706ba0bf8e441e881bbea 301 PANTHER PTHR30269 4 141 1.7E-42 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 DC74_RS17905 e2a54ce172e706ba0bf8e441e881bbea 301 PANTHER PTHR30269 158 298 1.7E-42 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 DC74_RS17905 e2a54ce172e706ba0bf8e441e881bbea 301 Pfam PF01925 Sulfite exporter TauE/SafE 10 293 1.8E-51 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 DC74_RS17905 e2a54ce172e706ba0bf8e441e881bbea 301 PANTHER PTHR30269:SF14 158 298 1.7E-42 T 23-04-2016 DC74_RS17905 e2a54ce172e706ba0bf8e441e881bbea 301 PANTHER PTHR30269:SF14 4 141 1.7E-42 T 23-04-2016 DC74_RS20755 ffb770025be6c5aa2e5a6efedeb10f49 572 PANTHER PTHR24362:SF160 64 284 4.6E-12 T 23-04-2016 DC74_RS20755 ffb770025be6c5aa2e5a6efedeb10f49 572 SUPERFAMILY SSF56112 87 248 1.88E-14 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS20755 ffb770025be6c5aa2e5a6efedeb10f49 572 PANTHER PTHR24362 64 284 4.6E-12 T 23-04-2016 DC74_RS20755 ffb770025be6c5aa2e5a6efedeb10f49 572 Gene3D G3DSA:2.60.120.260 434 548 6.4E-7 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS20755 ffb770025be6c5aa2e5a6efedeb10f49 572 Gene3D G3DSA:1.10.510.10 123 210 5.0E-9 T 23-04-2016 DC74_RS12685 a9863cd431ff0b7feb7de72419756aac 133 Pfam PF13411 MerR HTH family regulatory protein 2 67 1.1E-18 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS12685 a9863cd431ff0b7feb7de72419756aac 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.1E-8 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS12685 a9863cd431ff0b7feb7de72419756aac 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 7.1E-8 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS12685 a9863cd431ff0b7feb7de72419756aac 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.1E-8 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS12685 a9863cd431ff0b7feb7de72419756aac 133 PANTHER PTHR30204 1 115 1.8E-31 T 23-04-2016 DC74_RS12685 a9863cd431ff0b7feb7de72419756aac 133 Gene3D G3DSA:1.10.1660.10 2 116 8.9E-29 T 23-04-2016 DC74_RS12685 a9863cd431ff0b7feb7de72419756aac 133 PANTHER PTHR30204:SF4 1 115 1.8E-31 T 23-04-2016 DC74_RS12685 a9863cd431ff0b7feb7de72419756aac 133 SUPERFAMILY SSF46955 2 115 4.03E-25 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS12685 a9863cd431ff0b7feb7de72419756aac 133 SMART SM00422 1 69 5.1E-22 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS01010 32e0dc87da2cc575a93105661d7057b5 277 Gene3D G3DSA:3.40.50.10320 6 276 2.8E-76 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS01010 32e0dc87da2cc575a93105661d7057b5 277 PANTHER PTHR12993 2 233 6.5E-71 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS01010 32e0dc87da2cc575a93105661d7057b5 277 SUPERFAMILY SSF102588 5 276 1.27E-62 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS01010 32e0dc87da2cc575a93105661d7057b5 277 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 156 3.0E-28 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS01010 32e0dc87da2cc575a93105661d7057b5 277 PANTHER PTHR12993:SF13 2 233 6.5E-71 T 23-04-2016 DC74_RS08600 2b78f32d1854280d6af40dc70ae31035 312 SMART SM01150 10 310 8.4E-117 T 23-04-2016 IPR009770 Domain of unknown function DUF1338 DC74_RS08600 2b78f32d1854280d6af40dc70ae31035 312 PANTHER PTHR39479 6 312 9.3E-141 T 23-04-2016 DC74_RS08600 2b78f32d1854280d6af40dc70ae31035 312 Pfam PF07063 Domain of unknown function (DUF1338) 8 311 3.0E-84 T 23-04-2016 IPR009770 Domain of unknown function DUF1338 DC74_RS08600 2b78f32d1854280d6af40dc70ae31035 312 PANTHER PTHR39479:SF1 6 312 9.3E-141 T 23-04-2016 DC74_RS35510 d43ed5bd1efcc6eea543a88e736554fa 380 Pfam PF02661 Fic/DOC family 109 210 5.6E-15 T 23-04-2016 IPR003812 Fido domain DC74_RS35510 d43ed5bd1efcc6eea543a88e736554fa 380 SUPERFAMILY SSF140931 86 280 9.94E-26 T 23-04-2016 IPR003812 Fido domain DC74_RS35510 d43ed5bd1efcc6eea543a88e736554fa 380 PANTHER PTHR13504 10 370 9.7E-30 T 23-04-2016 DC74_RS35510 d43ed5bd1efcc6eea543a88e736554fa 380 Gene3D G3DSA:1.10.3290.10 15 283 3.3E-48 T 23-04-2016 IPR003812 Fido domain DC74_RS05640 34503db2bd11a25b52f8b5c006767f28 311 Pfam PF00348 Polyprenyl synthetase 47 279 2.4E-51 T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 DC74_RS05640 34503db2bd11a25b52f8b5c006767f28 311 PANTHER PTHR12001:SF58 1 292 8.9E-126 T 23-04-2016 DC74_RS05640 34503db2bd11a25b52f8b5c006767f28 311 PANTHER PTHR12001 1 292 8.9E-126 T 23-04-2016 IPR017446 Polyprenyl synthetase-related DC74_RS05640 34503db2bd11a25b52f8b5c006767f28 311 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 97 113 - T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 DC74_RS05640 34503db2bd11a25b52f8b5c006767f28 311 Gene3D G3DSA:1.10.600.10 19 304 6.6E-91 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS05640 34503db2bd11a25b52f8b5c006767f28 311 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 230 242 - T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 DC74_RS05640 34503db2bd11a25b52f8b5c006767f28 311 SUPERFAMILY SSF48576 24 301 6.02E-80 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS12900 48e7773ddb92bf000ca2253198666980 206 Gene3D G3DSA:1.20.120.80 25 205 1.6E-54 T 23-04-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 DC74_RS12900 48e7773ddb92bf000ca2253198666980 206 Pfam PF00510 Cytochrome c oxidase subunit III 25 204 5.6E-24 T 23-04-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 DC74_RS12900 48e7773ddb92bf000ca2253198666980 206 PANTHER PTHR11403:SF0 14 205 7.0E-71 T 23-04-2016 DC74_RS12900 48e7773ddb92bf000ca2253198666980 206 SUPERFAMILY SSF81452 9 205 1.31E-54 T 23-04-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 DC74_RS12900 48e7773ddb92bf000ca2253198666980 206 PANTHER PTHR11403 14 205 7.0E-71 T 23-04-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 DC74_RS07520 c507c7fd5ef2c33062cfd29f4c373c83 525 SUPERFAMILY SSF55781 43 190 5.23E-18 T 23-04-2016 IPR029016 GAF domain-like DC74_RS07520 c507c7fd5ef2c33062cfd29f4c373c83 525 Gene3D G3DSA:3.30.450.40 112 172 1.0E-6 T 23-04-2016 IPR029016 GAF domain-like DC74_RS07520 c507c7fd5ef2c33062cfd29f4c373c83 525 Gene3D G3DSA:3.30.450.40 49 104 2.6E-6 T 23-04-2016 IPR029016 GAF domain-like DC74_RS07520 c507c7fd5ef2c33062cfd29f4c373c83 525 Gene3D G3DSA:3.30.450.40 204 339 1.3E-14 T 23-04-2016 IPR029016 GAF domain-like DC74_RS07520 c507c7fd5ef2c33062cfd29f4c373c83 525 Pfam PF07730 Histidine kinase 356 416 1.0E-11 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS07520 c507c7fd5ef2c33062cfd29f4c373c83 525 Pfam PF13185 GAF domain 205 338 2.1E-9 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS07520 c507c7fd5ef2c33062cfd29f4c373c83 525 SUPERFAMILY SSF55781 204 351 1.44E-15 T 23-04-2016 IPR029016 GAF domain-like DC74_RS07520 c507c7fd5ef2c33062cfd29f4c373c83 525 SMART SM00065 201 348 0.0061 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS07520 c507c7fd5ef2c33062cfd29f4c373c83 525 SMART SM00065 60 176 0.059 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS10185 a6008b37a3f268f72a600fa2405e0ecc 434 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 335 355 - T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 DC74_RS10185 a6008b37a3f268f72a600fa2405e0ecc 434 Pfam PF00860 Permease family 22 386 1.7E-56 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS10185 a6008b37a3f268f72a600fa2405e0ecc 434 PANTHER PTHR11119 13 415 4.6E-66 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS22570 7e504d2f2a2493e6b59574bdb0b6700e 354 SUPERFAMILY SSF54675 62 170 1.92E-25 T 23-04-2016 DC74_RS22570 7e504d2f2a2493e6b59574bdb0b6700e 354 PANTHER PTHR32179 44 338 1.3E-108 T 23-04-2016 DC74_RS22570 7e504d2f2a2493e6b59574bdb0b6700e 354 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 82 169 1.6E-22 T 23-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 DC74_RS22570 7e504d2f2a2493e6b59574bdb0b6700e 354 SUPERFAMILY SSF51690 171 336 1.57E-56 T 23-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 DC74_RS22570 7e504d2f2a2493e6b59574bdb0b6700e 354 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 171 335 9.3E-56 T 23-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 DC74_RS22570 7e504d2f2a2493e6b59574bdb0b6700e 354 Gene3D G3DSA:3.20.20.70 192 326 1.5E-55 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS22570 7e504d2f2a2493e6b59574bdb0b6700e 354 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 73 335 4.7E-90 T 23-04-2016 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|UniPathway: UPA00253 DC74_RS22570 7e504d2f2a2493e6b59574bdb0b6700e 354 Gene3D G3DSA:3.90.1170.20 61 191 1.4E-43 T 23-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 DC74_RS00935 955ed34528cb49298407e9d2a5b1b54f 323 Gene3D G3DSA:3.40.50.720 24 278 9.4E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00935 955ed34528cb49298407e9d2a5b1b54f 323 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 168 6.711506E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00935 955ed34528cb49298407e9d2a5b1b54f 323 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 103 114 6.711506E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00935 955ed34528cb49298407e9d2a5b1b54f 323 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 30 47 6.711506E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00935 955ed34528cb49298407e9d2a5b1b54f 323 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 229 6.711506E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00935 955ed34528cb49298407e9d2a5b1b54f 323 PANTHER PTHR24320 10 322 3.9E-87 T 23-04-2016 DC74_RS00935 955ed34528cb49298407e9d2a5b1b54f 323 SUPERFAMILY SSF51735 27 284 1.6E-49 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00935 955ed34528cb49298407e9d2a5b1b54f 323 Pfam PF00106 short chain dehydrogenase 31 234 9.5E-26 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11705 3cb89e13b65153a2bddf51580b6300c4 111 PANTHER PTHR13696:SF62 12 111 6.8E-18 T 23-04-2016 DC74_RS11705 3cb89e13b65153a2bddf51580b6300c4 111 Pfam PF01883 Domain of unknown function DUF59 13 73 3.4E-19 T 23-04-2016 IPR002744 Domain of unknown function DUF59 DC74_RS11705 3cb89e13b65153a2bddf51580b6300c4 111 SUPERFAMILY SSF117916 11 105 5.89E-28 T 23-04-2016 DC74_RS11705 3cb89e13b65153a2bddf51580b6300c4 111 PANTHER PTHR13696 12 111 6.8E-18 T 23-04-2016 DC74_RS17530 9e223a7b02df83ee026514425674e06e 165 SUPERFAMILY SSF46785 11 159 4.07E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17530 9e223a7b02df83ee026514425674e06e 165 Pfam PF01047 MarR family 54 111 1.9E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS17530 9e223a7b02df83ee026514425674e06e 165 PANTHER PTHR33164:SF4 2 156 1.0E-31 T 23-04-2016 DC74_RS17530 9e223a7b02df83ee026514425674e06e 165 Gene3D G3DSA:1.10.10.10 9 158 1.3E-35 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17530 9e223a7b02df83ee026514425674e06e 165 SMART SM00347 43 146 1.0E-20 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS17530 9e223a7b02df83ee026514425674e06e 165 PANTHER PTHR33164 2 156 1.0E-31 T 23-04-2016 DC74_RS17530 9e223a7b02df83ee026514425674e06e 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS17530 9e223a7b02df83ee026514425674e06e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 5.222188E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS17530 9e223a7b02df83ee026514425674e06e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 5.222188E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS17530 9e223a7b02df83ee026514425674e06e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 5.222188E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS30155 61bb827b1feb24abe8a47f65b7a0da8e 237 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 3 237 2.5E-58 T 23-04-2016 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 DC74_RS30155 61bb827b1feb24abe8a47f65b7a0da8e 237 PANTHER PTHR36852 4 237 6.2E-37 T 23-04-2016 DC74_RS30155 61bb827b1feb24abe8a47f65b7a0da8e 237 PANTHER PTHR36852:SF1 4 237 6.2E-37 T 23-04-2016 DC74_RS27535 fcc8ff8d9cb6df300e65e2e84b70ed32 230 PANTHER PTHR30417:SF1 77 223 3.4E-54 T 23-04-2016 DC74_RS27535 fcc8ff8d9cb6df300e65e2e84b70ed32 230 PANTHER PTHR30417 77 223 3.4E-54 T 23-04-2016 DC74_RS27535 fcc8ff8d9cb6df300e65e2e84b70ed32 230 SMART SM00644 77 207 4.6E-35 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS27535 fcc8ff8d9cb6df300e65e2e84b70ed32 230 SUPERFAMILY SSF55846 76 223 7.72E-39 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS27535 fcc8ff8d9cb6df300e65e2e84b70ed32 230 Gene3D G3DSA:3.40.80.10 78 223 5.5E-39 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS27535 fcc8ff8d9cb6df300e65e2e84b70ed32 230 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 87 208 3.3E-20 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS18765 cd63ec90e9507b3566c4f0038085ea9b 162 Pfam PF08044 Domain of unknown function (DUF1707) 1 53 2.2E-21 T 23-04-2016 IPR012551 Protein of unknown function DUF1707 DC74_RS18765 cd63ec90e9507b3566c4f0038085ea9b 162 PANTHER PTHR40763 1 55 2.1E-13 T 23-04-2016 DC74_RS18765 cd63ec90e9507b3566c4f0038085ea9b 162 Pfam PF13828 Domain of unknown function (DUF4190) 90 150 1.2E-21 T 23-04-2016 IPR025241 Domain of unknown function DUF4190 DC74_RS18765 cd63ec90e9507b3566c4f0038085ea9b 162 PANTHER PTHR40763:SF1 1 55 2.1E-13 T 23-04-2016 DC74_RS32750 878db1f57d61a7e22462d481e5080c5b 396 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 26 396 5.0E-93 T 23-04-2016 DC74_RS32750 878db1f57d61a7e22462d481e5080c5b 396 PANTHER PTHR23100:SF0 15 396 5.2E-137 T 23-04-2016 DC74_RS32750 878db1f57d61a7e22462d481e5080c5b 396 PANTHER PTHR23100 15 396 5.2E-137 T 23-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS32750 878db1f57d61a7e22462d481e5080c5b 396 Pfam PF01960 ArgJ family 22 396 7.8E-124 T 23-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS32750 878db1f57d61a7e22462d481e5080c5b 396 Gene3D G3DSA:3.60.70.12 14 268 8.5E-81 T 23-04-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS32750 878db1f57d61a7e22462d481e5080c5b 396 SUPERFAMILY SSF56266 14 393 2.49E-118 T 23-04-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS32750 878db1f57d61a7e22462d481e5080c5b 396 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 396 112.853 T 23-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS32750 878db1f57d61a7e22462d481e5080c5b 396 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 15 396 6.8E-107 T 23-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 DC74_RS05635 8816565076f4d313159ebd787637f3ca 364 Pfam PF00355 Rieske [2Fe-2S] domain 24 107 1.5E-15 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS05635 8816565076f4d313159ebd787637f3ca 364 Gene3D G3DSA:2.102.10.10 24 134 2.8E-28 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS05635 8816565076f4d313159ebd787637f3ca 364 SUPERFAMILY SSF50022 21 130 9.43E-32 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS05635 8816565076f4d313159ebd787637f3ca 364 SUPERFAMILY SSF55961 121 354 1.4E-9 T 23-04-2016 DC74_RS05635 8816565076f4d313159ebd787637f3ca 364 PANTHER PTHR21266 24 181 3.9E-41 T 23-04-2016 DC74_RS38055 18362d57945054354a3177c29e512f67 349 PANTHER PTHR10457 25 321 1.5E-20 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS38055 18362d57945054354a3177c29e512f67 349 Gene3D G3DSA:3.30.230.10 27 179 1.8E-15 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS38055 18362d57945054354a3177c29e512f67 349 SUPERFAMILY SSF54211 19 180 1.75E-20 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS38055 18362d57945054354a3177c29e512f67 349 Pfam PF00288 GHMP kinases N terminal domain 101 172 4.6E-8 T 23-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 DC74_RS38055 18362d57945054354a3177c29e512f67 349 Gene3D G3DSA:3.30.70.890 194 313 3.1E-15 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain DC74_RS38055 18362d57945054354a3177c29e512f67 349 PRINTS PR00959 Mevalonate kinase family signature 28 52 3.9E-15 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS38055 18362d57945054354a3177c29e512f67 349 PRINTS PR00959 Mevalonate kinase family signature 289 306 3.9E-15 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS38055 18362d57945054354a3177c29e512f67 349 PRINTS PR00959 Mevalonate kinase family signature 105 127 3.9E-15 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS38055 18362d57945054354a3177c29e512f67 349 PRINTS PR00959 Mevalonate kinase family signature 152 171 3.9E-15 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 DC74_RS38055 18362d57945054354a3177c29e512f67 349 SUPERFAMILY SSF55060 193 324 8.87E-22 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain DC74_RS38055 18362d57945054354a3177c29e512f67 349 Pfam PF08544 GHMP kinases C terminal 245 321 7.2E-7 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 Pfam PF13183 4Fe-4S dicluster domain 531 613 3.4E-9 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 Pfam PF01565 FAD binding domain 34 171 4.7E-43 T 23-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 Gene3D G3DSA:3.30.465.10 88 256 8.7E-34 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 SUPERFAMILY SSF56176 3 256 2.94E-59 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 SUPERFAMILY SSF55103 229 496 5.4E-54 T 23-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 Pfam PF02913 FAD linked oxidases, C-terminal domain 256 493 3.3E-48 T 23-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 Gene3D G3DSA:1.10.1060.10 531 626 2.8E-11 T 23-04-2016 DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 Gene3D G3DSA:3.30.43.10 4 86 9.6E-24 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 PANTHER PTHR11748:SF35 1 175 7.5E-134 T 23-04-2016 DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 PANTHER PTHR11748:SF35 223 543 7.5E-134 T 23-04-2016 DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 PANTHER PTHR11748 1 175 7.5E-134 T 23-04-2016 DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 PANTHER PTHR11748 223 543 7.5E-134 T 23-04-2016 DC74_RS23835 d24fe14fdae575884bb577b62a485c63 963 SUPERFAMILY SSF46548 514 618 1.31E-7 T 23-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 DC74_RS34400 2be3922c900c9b34410a41fd3dfb116e 184 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 165 1.5E-8 T 23-04-2016 IPR001451 Hexapeptide repeat DC74_RS34400 2be3922c900c9b34410a41fd3dfb116e 184 SUPERFAMILY SSF51161 3 183 4.57E-47 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS34400 2be3922c900c9b34410a41fd3dfb116e 184 PANTHER PTHR23416:SF58 5 184 1.1E-63 T 23-04-2016 DC74_RS34400 2be3922c900c9b34410a41fd3dfb116e 184 Gene3D G3DSA:2.160.10.10 4 184 1.7E-51 T 23-04-2016 DC74_RS34400 2be3922c900c9b34410a41fd3dfb116e 184 Pfam PF12464 Maltose acetyltransferase 9 56 2.7E-9 T 23-04-2016 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 DC74_RS34400 2be3922c900c9b34410a41fd3dfb116e 184 PANTHER PTHR23416 5 184 1.1E-63 T 23-04-2016 DC74_RS34400 2be3922c900c9b34410a41fd3dfb116e 184 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 23-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 DC74_RS34400 2be3922c900c9b34410a41fd3dfb116e 184 SMART SM01266 5 59 5.8E-9 T 23-04-2016 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 DC74_RS38870 137008915975dbc56f4d6086d08f23a5 454 Gene3D G3DSA:3.40.605.10 78 284 5.8E-8 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS38870 137008915975dbc56f4d6086d08f23a5 454 SUPERFAMILY SSF53720 12 440 4.71E-20 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS38870 137008915975dbc56f4d6086d08f23a5 454 Pfam PF00171 Aldehyde dehydrogenase family 161 359 2.2E-6 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS20800 45569ddad13be7dc22066351e896cf4e 493 Pfam PF09594 Protein of unknown function (DUF2029) 115 359 4.1E-12 T 23-04-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 DC74_RS20800 45569ddad13be7dc22066351e896cf4e 493 PIRSF PIRSF010361 10 465 1.7E-146 T 23-04-2016 IPR016570 Uncharacterised conserved protein UCP010361, membrane DC74_RS16100 65c32b07105d70ad3c80e0e49a141420 314 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 73 293 1.4E-36 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS16100 65c32b07105d70ad3c80e0e49a141420 314 Gene3D G3DSA:3.40.190.10 43 172 4.9E-23 T 23-04-2016 DC74_RS16100 65c32b07105d70ad3c80e0e49a141420 314 SMART SM00062 70 300 4.4E-30 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS16100 65c32b07105d70ad3c80e0e49a141420 314 PANTHER PTHR18966:SF216 63 294 7.4E-43 T 23-04-2016 DC74_RS16100 65c32b07105d70ad3c80e0e49a141420 314 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 52 312 6.3E-74 T 23-04-2016 IPR014337 Ectoine/Hydroxyectoine-binding protein EhuB GO:0005886|GO:0033294|GO:0051470|GO:0051471 DC74_RS16100 65c32b07105d70ad3c80e0e49a141420 314 SUPERFAMILY SSF53850 67 296 1.71E-38 T 23-04-2016 DC74_RS16100 65c32b07105d70ad3c80e0e49a141420 314 Gene3D G3DSA:3.40.190.10 173 245 2.5E-6 T 23-04-2016 DC74_RS16100 65c32b07105d70ad3c80e0e49a141420 314 PANTHER PTHR18966 63 294 7.4E-43 T 23-04-2016 DC74_RS06460 b34324b386f1646de21e51f2077a342c 106 Gene3D G3DSA:3.30.70.900 1 105 2.2E-25 T 23-04-2016 DC74_RS06460 b34324b386f1646de21e51f2077a342c 106 SUPERFAMILY SSF54909 1 104 4.02E-32 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS06460 b34324b386f1646de21e51f2077a342c 106 Pfam PF07978 NIPSNAP 5 104 9.0E-30 T 23-04-2016 IPR012577 NIPSNAP DC74_RS09350 398b6b2ead13badbd8f3112e057c0ccc 740 Pfam PF03971 Monomeric isocitrate dehydrogenase 5 735 0.0 T 23-04-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 DC74_RS09350 398b6b2ead13badbd8f3112e057c0ccc 740 Gene3D G3DSA:3.40.718.10 536 643 4.9E-30 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS09350 398b6b2ead13badbd8f3112e057c0ccc 740 Gene3D G3DSA:3.40.718.10 147 284 4.9E-30 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS09350 398b6b2ead13badbd8f3112e057c0ccc 740 Gene3D G3DSA:3.40.718.10 337 360 4.9E-30 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 DC74_RS09350 398b6b2ead13badbd8f3112e057c0ccc 740 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 3 739 0.0 T 23-04-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 DC74_RS09350 398b6b2ead13badbd8f3112e057c0ccc 740 PANTHER PTHR36999 1 740 0.0 T 23-04-2016 DC74_RS09350 398b6b2ead13badbd8f3112e057c0ccc 740 PIRSF PIRSF009407 1 739 0.0 T 23-04-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 DC74_RS09350 398b6b2ead13badbd8f3112e057c0ccc 740 SUPERFAMILY SSF53659 4 738 0.0 T 23-04-2016 DC74_RS15920 954f56da9b2f2bf0a917d434837ee007 383 Gene3D G3DSA:1.20.140.10 222 381 6.8E-67 T 23-04-2016 DC74_RS15920 954f56da9b2f2bf0a917d434837ee007 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS15920 954f56da9b2f2bf0a917d434837ee007 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 221 1.7E-22 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS15920 954f56da9b2f2bf0a917d434837ee007 383 Gene3D G3DSA:1.10.540.10 3 119 1.3E-40 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS15920 954f56da9b2f2bf0a917d434837ee007 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 2.3E-50 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS15920 954f56da9b2f2bf0a917d434837ee007 383 SUPERFAMILY SSF47203 231 381 2.42E-52 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS15920 954f56da9b2f2bf0a917d434837ee007 383 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 23-04-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DC74_RS15920 954f56da9b2f2bf0a917d434837ee007 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.7E-37 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS15920 954f56da9b2f2bf0a917d434837ee007 383 PANTHER PTHR10909 5 381 3.1E-151 T 23-04-2016 DC74_RS15920 954f56da9b2f2bf0a917d434837ee007 383 Gene3D G3DSA:2.40.110.10 121 221 5.5E-35 T 23-04-2016 DC74_RS15920 954f56da9b2f2bf0a917d434837ee007 383 SUPERFAMILY SSF56645 2 246 3.14E-81 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS27370 919dd5d6971442f35d085ccce3d8ce91 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 249 2.6E-69 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS27370 919dd5d6971442f35d085ccce3d8ce91 255 PANTHER PTHR11941:SF93 2 254 1.8E-118 T 23-04-2016 DC74_RS27370 919dd5d6971442f35d085ccce3d8ce91 255 Gene3D G3DSA:3.90.226.10 2 247 1.3E-86 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS27370 919dd5d6971442f35d085ccce3d8ce91 255 PANTHER PTHR11941 2 254 1.8E-118 T 23-04-2016 DC74_RS27370 919dd5d6971442f35d085ccce3d8ce91 255 SUPERFAMILY SSF52096 3 253 9.81E-84 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS27370 919dd5d6971442f35d085ccce3d8ce91 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 23-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 DC74_RS21670 ce467c18cb5c145d5edd668dc8d741d9 216 Pfam PF14016 Protein of unknown function (DUF4232) 73 207 7.9E-11 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS00485 43a5fa875726ef0f6645f84a62438e0f 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 4.8E-14 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS00485 43a5fa875726ef0f6645f84a62438e0f 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 4.8E-14 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS00485 43a5fa875726ef0f6645f84a62438e0f 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 4.8E-14 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS00485 43a5fa875726ef0f6645f84a62438e0f 104 SMART SM00418 8 86 7.4E-27 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS00485 43a5fa875726ef0f6645f84a62438e0f 104 SUPERFAMILY SSF46785 6 93 4.23E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00485 43a5fa875726ef0f6645f84a62438e0f 104 Pfam PF01022 Bacterial regulatory protein, arsR family 15 61 1.6E-13 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS00485 43a5fa875726ef0f6645f84a62438e0f 104 Gene3D G3DSA:1.10.10.10 8 88 1.5E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00485 43a5fa875726ef0f6645f84a62438e0f 104 PANTHER PTHR33154 7 98 4.3E-31 T 23-04-2016 DC74_RS00485 43a5fa875726ef0f6645f84a62438e0f 104 PANTHER PTHR33154:SF6 7 98 4.3E-31 T 23-04-2016 DC74_RS37550 7e2ec34bc646648ab7533e1a33b4d9ba 228 SMART SM00860 79 209 1.1E-4 T 23-04-2016 IPR018958 SMI1/KNR4-like domain DC74_RS37550 7e2ec34bc646648ab7533e1a33b4d9ba 228 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 79 174 1.5E-8 T 23-04-2016 IPR018958 SMI1/KNR4-like domain DC74_RS37550 7e2ec34bc646648ab7533e1a33b4d9ba 228 SUPERFAMILY SSF160631 59 175 5.76E-6 T 23-04-2016 DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 325 503 3.9E-62 T 23-04-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 209 3.3E-32 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 SUPERFAMILY SSF48179 634 732 1.96E-15 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 Gene3D G3DSA:3.90.226.10 243 302 7.8E-54 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 Gene3D G3DSA:3.90.226.10 7 209 7.8E-54 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 Gene3D G3DSA:3.40.50.720 320 507 6.6E-57 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 506 606 1.4E-16 T 23-04-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 Gene3D G3DSA:1.10.1040.10 647 732 1.4E-8 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 Gene3D G3DSA:1.10.1040.10 508 606 2.4E-9 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 PANTHER PTHR23309 10 732 0.0 T 23-04-2016 DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 SUPERFAMILY SSF48179 505 646 3.23E-14 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 SUPERFAMILY SSF52096 8 316 2.96E-60 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 PANTHER PTHR23309:SF6 10 732 0.0 T 23-04-2016 DC74_RS33025 e6a7b927673b9d96e4fdcd87ffb3ca02 734 SUPERFAMILY SSF51735 322 504 3.11E-56 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10945 c99947a863688f3b180a3975db48178f 397 Gene3D G3DSA:1.10.540.10 9 139 3.2E-37 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS10945 c99947a863688f3b180a3975db48178f 397 Gene3D G3DSA:1.20.140.10 248 394 9.7E-40 T 23-04-2016 DC74_RS10945 c99947a863688f3b180a3975db48178f 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 137 1.5E-28 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS10945 c99947a863688f3b180a3975db48178f 397 Gene3D G3DSA:2.40.110.10 140 240 2.6E-37 T 23-04-2016 DC74_RS10945 c99947a863688f3b180a3975db48178f 397 PANTHER PTHR10909:SF152 9 397 7.6E-222 T 23-04-2016 DC74_RS10945 c99947a863688f3b180a3975db48178f 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 390 6.5E-29 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS10945 c99947a863688f3b180a3975db48178f 397 SUPERFAMILY SSF47203 243 393 1.93E-39 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS10945 c99947a863688f3b180a3975db48178f 397 PANTHER PTHR10909 9 397 7.6E-222 T 23-04-2016 DC74_RS10945 c99947a863688f3b180a3975db48178f 397 SUPERFAMILY SSF56645 11 241 1.44E-74 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS10945 c99947a863688f3b180a3975db48178f 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 141 231 2.4E-23 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS28605 f08733177d8bdd5ee3fcef3d5a1bb0f8 248 SUPERFAMILY SSF69796 14 241 1.7E-52 T 23-04-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 DC74_RS28605 f08733177d8bdd5ee3fcef3d5a1bb0f8 248 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 21 240 4.6E-62 T 23-04-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 DC74_RS28605 f08733177d8bdd5ee3fcef3d5a1bb0f8 248 PANTHER PTHR34934 14 246 7.6E-56 T 23-04-2016 DC74_RS28605 f08733177d8bdd5ee3fcef3d5a1bb0f8 248 Hamap MF_01408 Thymidylate synthase ThyX [thyX]. 15 248 27.472 T 23-04-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 DC74_RS28605 f08733177d8bdd5ee3fcef3d5a1bb0f8 248 Pfam PF02511 Thymidylate synthase complementing protein 22 234 6.3E-50 T 23-04-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 DC74_RS28725 c5f6ece3083bf316ed7cfd96286e1b04 314 Gene3D G3DSA:1.50.10.20 76 164 1.8E-5 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS28725 c5f6ece3083bf316ed7cfd96286e1b04 314 Gene3D G3DSA:1.50.10.20 259 311 1.8E-5 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS28725 c5f6ece3083bf316ed7cfd96286e1b04 314 SUPERFAMILY SSF48239 259 311 3.14E-11 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS28725 c5f6ece3083bf316ed7cfd96286e1b04 314 SUPERFAMILY SSF48239 48 197 3.14E-11 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS36820 cfee4470a69cfc2afc2e720e14271971 513 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 24 47 3.7 T 23-04-2016 IPR001330 PFTB repeat GO:0003824 DC74_RS36820 cfee4470a69cfc2afc2e720e14271971 513 SUPERFAMILY SSF48239 220 475 7.33E-38 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS36820 cfee4470a69cfc2afc2e720e14271971 513 SUPERFAMILY SSF48239 174 237 6.28E-14 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS36820 cfee4470a69cfc2afc2e720e14271971 513 SUPERFAMILY SSF48239 16 127 6.28E-14 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS36820 cfee4470a69cfc2afc2e720e14271971 513 PANTHER PTHR11764 337 471 3.8E-12 T 23-04-2016 DC74_RS36820 cfee4470a69cfc2afc2e720e14271971 513 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 204 332 4.5E-9 T 23-04-2016 IPR032696 Squalene cyclase, C-terminal DC74_RS36820 cfee4470a69cfc2afc2e720e14271971 513 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 337 472 8.4E-11 T 23-04-2016 IPR032696 Squalene cyclase, C-terminal DC74_RS36820 cfee4470a69cfc2afc2e720e14271971 513 PANTHER PTHR11764:SF12 337 471 3.8E-12 T 23-04-2016 DC74_RS36820 cfee4470a69cfc2afc2e720e14271971 513 Gene3D G3DSA:1.50.10.20 229 473 4.9E-45 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS36820 cfee4470a69cfc2afc2e720e14271971 513 Gene3D G3DSA:1.50.10.20 13 228 4.3E-11 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS13935 e85b9ec3f61e7abd4595d7d9234189fd 191 Gene3D G3DSA:2.60.60.30 18 183 3.3E-72 T 23-04-2016 DC74_RS13935 e85b9ec3f61e7abd4595d7d9234189fd 191 PANTHER PTHR32097 1 190 3.7E-93 T 23-04-2016 DC74_RS13935 e85b9ec3f61e7abd4595d7d9234189fd 191 Pfam PF02342 TerD domain 1 186 2.0E-81 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS00815 7febdab349b4b39b99224490946fb3cc 333 SUPERFAMILY SSF53335 69 204 2.13E-10 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS00815 7febdab349b4b39b99224490946fb3cc 333 Gene3D G3DSA:3.40.50.150 69 209 7.5E-8 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS13815 044930a84a7c08d65ff9536760c26669 154 PANTHER PTHR33452:SF4 10 152 3.8E-60 T 23-04-2016 DC74_RS13815 044930a84a7c08d65ff9536760c26669 154 PANTHER PTHR33452 10 152 3.8E-60 T 23-04-2016 DC74_RS13815 044930a84a7c08d65ff9536760c26669 154 Pfam PF07681 DoxX 17 96 2.5E-9 T 23-04-2016 IPR032808 DoxX family DC74_RS32720 2040a6ea8cf13ff4ea8291bd05f0cdaa 226 PANTHER PTHR35336 24 224 8.8E-56 T 23-04-2016 DC74_RS32720 2040a6ea8cf13ff4ea8291bd05f0cdaa 226 PANTHER PTHR35336:SF2 24 224 8.8E-56 T 23-04-2016 DC74_RS32720 2040a6ea8cf13ff4ea8291bd05f0cdaa 226 Pfam PF01955 Adenosylcobinamide amidohydrolase 39 219 8.5E-48 T 23-04-2016 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ DC74_RS24805 c990730a5686d56fcea867de554fade2 569 PANTHER PTHR22600 158 569 2.5E-58 T 23-04-2016 DC74_RS24805 c990730a5686d56fcea867de554fade2 569 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 82 214 2.6E-13 T 23-04-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS24805 c990730a5686d56fcea867de554fade2 569 Gene3D G3DSA:3.30.379.10 77 204 2.3E-14 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like DC74_RS24805 c990730a5686d56fcea867de554fade2 569 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 221 550 6.6E-40 T 23-04-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS24805 c990730a5686d56fcea867de554fade2 569 SUPERFAMILY SSF55545 81 217 1.11E-12 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like DC74_RS24805 c990730a5686d56fcea867de554fade2 569 PRINTS PR00738 Glycosyl hydrolase family 20 signature 180 200 3.6E-19 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS24805 c990730a5686d56fcea867de554fade2 569 PRINTS PR00738 Glycosyl hydrolase family 20 signature 241 262 3.6E-19 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS24805 c990730a5686d56fcea867de554fade2 569 PRINTS PR00738 Glycosyl hydrolase family 20 signature 331 349 3.6E-19 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS24805 c990730a5686d56fcea867de554fade2 569 PRINTS PR00738 Glycosyl hydrolase family 20 signature 353 366 3.6E-19 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS24805 c990730a5686d56fcea867de554fade2 569 PRINTS PR00738 Glycosyl hydrolase family 20 signature 514 530 3.6E-19 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS24805 c990730a5686d56fcea867de554fade2 569 PRINTS PR00738 Glycosyl hydrolase family 20 signature 212 229 3.6E-19 T 23-04-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 DC74_RS24805 c990730a5686d56fcea867de554fade2 569 Gene3D G3DSA:3.20.20.80 205 564 1.8E-67 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS24805 c990730a5686d56fcea867de554fade2 569 SUPERFAMILY SSF51445 219 562 9.27E-69 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS35255 5d36897f42d59a4de9a1b52091c9e402 467 Gene3D G3DSA:3.40.630.30 292 427 1.1E-16 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS35255 5d36897f42d59a4de9a1b52091c9e402 467 Gene3D G3DSA:3.30.70.260 108 168 6.4E-5 T 23-04-2016 DC74_RS35255 5d36897f42d59a4de9a1b52091c9e402 467 SUPERFAMILY SSF55729 276 427 8.19E-20 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS35255 5d36897f42d59a4de9a1b52091c9e402 467 Pfam PF00583 Acetyltransferase (GNAT) family 358 420 1.8E-6 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS35255 5d36897f42d59a4de9a1b52091c9e402 467 SUPERFAMILY SSF55021 105 167 1.3E-5 T 23-04-2016 DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 SUPERFAMILY SSF53474 2 285 2.63E-72 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 6.3E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 6.3E-6 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 Gene3D G3DSA:3.40.50.1820 2 285 7.1E-67 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 PANTHER PTHR10992 4 170 3.3E-118 T 23-04-2016 DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 PANTHER PTHR10992 186 285 3.3E-118 T 23-04-2016 DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 PRINTS PR00412 Epoxide hydrolase signature 260 282 5.2E-10 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 PRINTS PR00412 Epoxide hydrolase signature 99 112 5.2E-10 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 PRINTS PR00412 Epoxide hydrolase signature 228 244 5.2E-10 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 PRINTS PR00412 Epoxide hydrolase signature 113 126 5.2E-10 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 PRINTS PR00412 Epoxide hydrolase signature 33 51 5.2E-10 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 Pfam PF00561 alpha/beta hydrolase fold 27 269 6.6E-29 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 PANTHER PTHR10992:SF870 4 170 3.3E-118 T 23-04-2016 DC74_RS36795 30de5ac96f2fb466c69cb1d3742d3e0c 288 PANTHER PTHR10992:SF870 186 285 3.3E-118 T 23-04-2016 DC74_RS28965 f3f2879aed885a9dd6779d3be630cad4 233 PANTHER PTHR10954 3 205 5.4E-53 T 23-04-2016 IPR001352 Ribonuclease HII/HIII GO:0003723|GO:0004523 DC74_RS28965 f3f2879aed885a9dd6779d3be630cad4 233 PANTHER PTHR10954:SF7 3 205 5.4E-53 T 23-04-2016 DC74_RS28965 f3f2879aed885a9dd6779d3be630cad4 233 Gene3D G3DSA:3.30.420.10 22 162 8.4E-39 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS28965 f3f2879aed885a9dd6779d3be630cad4 233 Pfam PF01351 Ribonuclease HII 24 200 4.6E-33 T 23-04-2016 IPR024567 Ribonuclease HII/HIII domain DC74_RS28965 f3f2879aed885a9dd6779d3be630cad4 233 SUPERFAMILY SSF53098 17 212 6.22E-58 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS28965 f3f2879aed885a9dd6779d3be630cad4 233 Hamap MF_00052_B Ribonuclease HII [rnhB]. 22 202 35.916 T 23-04-2016 IPR022898 Ribonuclease HII GO:0004523 DC74_RS34040 89b175afa9df4cc8269854a70cf23425 160 SUPERFAMILY SSF46785 7 148 1.57E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34040 89b175afa9df4cc8269854a70cf23425 160 PANTHER PTHR33164 16 160 1.7E-33 T 23-04-2016 DC74_RS34040 89b175afa9df4cc8269854a70cf23425 160 Gene3D G3DSA:1.10.10.10 5 148 1.3E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34040 89b175afa9df4cc8269854a70cf23425 160 SMART SM00347 34 136 3.3E-18 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS34040 89b175afa9df4cc8269854a70cf23425 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 7.9E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS34040 89b175afa9df4cc8269854a70cf23425 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 7.9E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS34040 89b175afa9df4cc8269854a70cf23425 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 7.9E-9 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS34040 89b175afa9df4cc8269854a70cf23425 160 PANTHER PTHR33164:SF11 16 160 1.7E-33 T 23-04-2016 DC74_RS34040 89b175afa9df4cc8269854a70cf23425 160 Pfam PF01047 MarR family 42 101 6.4E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS17115 5d4b06e6a1a85373673572b5c2b4d832 182 SUPERFAMILY SSF46785 104 170 2.36E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17115 5d4b06e6a1a85373673572b5c2b4d832 182 Gene3D G3DSA:1.10.10.10 110 166 1.0E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00330 75942b64c135ce2251792d298fbf2707 502 PANTHER PTHR11699 21 468 5.3E-184 T 23-04-2016 DC74_RS00330 75942b64c135ce2251792d298fbf2707 502 Gene3D G3DSA:3.40.605.10 16 260 1.6E-75 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS00330 75942b64c135ce2251792d298fbf2707 502 SUPERFAMILY SSF53720 14 476 1.7E-147 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS00330 75942b64c135ce2251792d298fbf2707 502 Gene3D G3DSA:3.40.309.10 261 439 1.0E-68 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS00330 75942b64c135ce2251792d298fbf2707 502 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS00330 75942b64c135ce2251792d298fbf2707 502 Pfam PF00171 Aldehyde dehydrogenase family 14 473 8.6E-152 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS25500 460b1882fea080ba25eeada3dc2ea45a 181 Gene3D G3DSA:1.20.1290.10 1 176 8.3E-58 T 23-04-2016 IPR029032 AhpD-like DC74_RS25500 460b1882fea080ba25eeada3dc2ea45a 181 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 116 164 1.6E-21 T 23-04-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS25500 460b1882fea080ba25eeada3dc2ea45a 181 TIGRFAM TIGR00777 ahpD: alkylhydroperoxidase, AhpD family 3 180 6.6E-89 T 23-04-2016 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS25500 460b1882fea080ba25eeada3dc2ea45a 181 SUPERFAMILY SSF69118 3 176 1.31E-47 T 23-04-2016 IPR029032 AhpD-like DC74_RS25500 460b1882fea080ba25eeada3dc2ea45a 181 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 181 85.411 T 23-04-2016 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS25500 460b1882fea080ba25eeada3dc2ea45a 181 Pfam PF02627 Carboxymuconolactone decarboxylase family 98 180 6.1E-17 T 23-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS08655 1165f31e2fca9e077c79f2cb6188b2de 486 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 45 442 1.7E-43 T 23-04-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 DC74_RS08655 1165f31e2fca9e077c79f2cb6188b2de 486 PIRSF PIRSF002744 14 486 6.4E-103 T 23-04-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 DC74_RS08655 1165f31e2fca9e077c79f2cb6188b2de 486 PANTHER PTHR31806 33 477 2.4E-65 T 23-04-2016 DC74_RS36165 39713161e5410c6d1b95ff78b810bd9a 85 SUPERFAMILY SSF47598 1 47 2.62E-6 T 23-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 DC74_RS36165 39713161e5410c6d1b95ff78b810bd9a 85 Gene3D G3DSA:1.10.1220.10 4 52 3.4E-5 T 23-04-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 404 528 6.2E-32 T 23-04-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 SUPERFAMILY SSF51905 290 351 6.48E-37 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 SUPERFAMILY SSF51905 24 253 6.48E-37 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 PANTHER PTHR11985 8 552 1.9E-221 T 23-04-2016 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 Pfam PF01266 FAD dependent oxidoreductase 24 377 6.1E-49 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 Gene3D G3DSA:3.50.50.60 18 238 1.6E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 PANTHER PTHR11985:SF1 8 552 1.9E-221 T 23-04-2016 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 46 1.2E-30 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 52 64 1.2E-30 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 341 347 1.2E-30 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 35 1.2E-30 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 371 383 1.2E-30 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 98 110 1.2E-30 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 376 386 - T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 DC74_RS18425 834a066bf9d8308395a0ab4ea69d66e5 569 Gene3D G3DSA:3.30.9.10 239 346 4.5E-4 T 23-04-2016 DC74_RS28310 6ab002db2e79c0070445616e240bdc7a 505 Gene3D G3DSA:3.40.309.10 274 464 1.8E-63 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS28310 6ab002db2e79c0070445616e240bdc7a 505 PANTHER PTHR11699 17 487 5.0E-291 T 23-04-2016 DC74_RS28310 6ab002db2e79c0070445616e240bdc7a 505 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS28310 6ab002db2e79c0070445616e240bdc7a 505 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS28310 6ab002db2e79c0070445616e240bdc7a 505 PANTHER PTHR11699:SF109 17 487 5.0E-291 T 23-04-2016 IPR015657 Aminobutyraldehyde dehydrogenase KEGG: 00330+1.2.1.19|KEGG: 00410+1.2.1.19|MetaCyc: PWY-2|MetaCyc: PWY-3|UniPathway: UPA00188 DC74_RS28310 6ab002db2e79c0070445616e240bdc7a 505 SUPERFAMILY SSF53720 15 488 1.57E-158 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS28310 6ab002db2e79c0070445616e240bdc7a 505 Gene3D G3DSA:3.40.605.10 17 273 7.5E-93 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS28310 6ab002db2e79c0070445616e240bdc7a 505 Pfam PF00171 Aldehyde dehydrogenase family 27 484 6.2E-169 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS32740 df4931fc75162596e25975a4a3c4729b 196 SUPERFAMILY SSF46785 30 166 5.75E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32740 df4931fc75162596e25975a4a3c4729b 196 Gene3D G3DSA:1.10.10.10 31 168 1.8E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32740 df4931fc75162596e25975a4a3c4729b 196 ProSitePatterns PS01117 MarR-type HTH domain signature. 92 126 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS32740 df4931fc75162596e25975a4a3c4729b 196 Pfam PF01047 MarR family 60 118 1.1E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32740 df4931fc75162596e25975a4a3c4729b 196 SMART SM00347 53 153 4.5E-13 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS32740 df4931fc75162596e25975a4a3c4729b 196 PANTHER PTHR33164 7 177 1.1E-20 T 23-04-2016 DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 Gene3D G3DSA:3.40.50.720 8 258 6.2E-83 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 SUPERFAMILY SSF51735 9 258 1.56E-78 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 PANTHER PTHR24321:SF6 8 258 1.3E-57 T 23-04-2016 DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 182 0.0071 T 23-04-2016 DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.2E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.2E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.2E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.2E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.2E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.2E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 8.4E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 8.4E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 8.4E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 PANTHER PTHR24321 8 258 1.3E-57 T 23-04-2016 DC74_RS37360 9de3652f0d105a031ed37170b640e479 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 256 5.5E-68 T 23-04-2016 DC74_RS31400 e14e9c87da44b5ab42787c15523cbb94 192 Gene3D G3DSA:3.90.550.10 2 191 3.9E-35 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS31400 e14e9c87da44b5ab42787c15523cbb94 192 PANTHER PTHR19136:SF78 1 192 4.2E-47 T 23-04-2016 DC74_RS31400 e14e9c87da44b5ab42787c15523cbb94 192 Pfam PF12804 MobA-like NTP transferase domain 3 164 2.3E-36 T 23-04-2016 IPR025877 MobA-like NTP transferase DC74_RS31400 e14e9c87da44b5ab42787c15523cbb94 192 PANTHER PTHR19136 1 192 4.2E-47 T 23-04-2016 DC74_RS31400 e14e9c87da44b5ab42787c15523cbb94 192 SUPERFAMILY SSF53448 2 188 5.86E-34 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS22035 cd701282b6afd219765842fba1de1861 300 SUPERFAMILY SSF55811 29 119 1.97E-14 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS22035 cd701282b6afd219765842fba1de1861 300 SUPERFAMILY SSF55811 164 230 1.97E-14 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS22035 cd701282b6afd219765842fba1de1861 300 PANTHER PTHR12318:SF0 1 281 1.2E-61 T 23-04-2016 DC74_RS22035 cd701282b6afd219765842fba1de1861 300 PANTHER PTHR12318 1 281 1.2E-61 T 23-04-2016 DC74_RS22035 cd701282b6afd219765842fba1de1861 300 Gene3D G3DSA:3.90.79.10 164 219 3.6E-17 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS22035 cd701282b6afd219765842fba1de1861 300 Gene3D G3DSA:3.90.79.10 26 119 3.6E-17 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS15295 1fe504a50e8f396fa05c1947a5fd48c3 482 PANTHER PTHR30627 1 481 1.7E-153 T 23-04-2016 DC74_RS15295 1fe504a50e8f396fa05c1947a5fd48c3 482 Gene3D G3DSA:3.90.1310.10 72 141 7.5E-6 T 23-04-2016 DC74_RS15295 1fe504a50e8f396fa05c1947a5fd48c3 482 Pfam PF00905 Penicillin binding protein transpeptidase domain 153 478 5.6E-64 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS15295 1fe504a50e8f396fa05c1947a5fd48c3 482 Gene3D G3DSA:3.40.710.10 142 481 6.1E-93 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS15295 1fe504a50e8f396fa05c1947a5fd48c3 482 SUPERFAMILY SSF56601 136 481 8.2E-85 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS15295 1fe504a50e8f396fa05c1947a5fd48c3 482 PANTHER PTHR30627:SF3 1 481 1.7E-153 T 23-04-2016 DC74_RS40730 903de74bf0475377c8c3801cfeb0dfe3 271 Pfam PF01636 Phosphotransferase enzyme family 4 207 5.0E-19 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS40730 903de74bf0475377c8c3801cfeb0dfe3 271 SUPERFAMILY SSF56112 4 239 2.55E-29 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS40730 903de74bf0475377c8c3801cfeb0dfe3 271 Gene3D G3DSA:3.90.1200.10 73 224 2.9E-12 T 23-04-2016 DC74_RS26580 0a2a6691caaa8f65b7c96bba31632d96 145 TIGRFAM TIGR00494 crcB: protein CrcB 20 131 3.6E-24 T 23-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 DC74_RS26580 0a2a6691caaa8f65b7c96bba31632d96 145 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 18 135 17.75 T 23-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 DC74_RS26580 0a2a6691caaa8f65b7c96bba31632d96 145 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 20 129 2.8E-20 T 23-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 DC74_RS26580 0a2a6691caaa8f65b7c96bba31632d96 145 PANTHER PTHR28259 18 145 1.3E-34 T 23-04-2016 DC74_RS29230 dad3998827fdfb1d78c79082d2dc290f 223 PANTHER PTHR16254 1 159 1.5E-23 T 23-04-2016 DC74_RS29230 dad3998827fdfb1d78c79082d2dc290f 223 Gene3D G3DSA:3.30.70.1450 147 217 6.2E-11 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 DC74_RS29230 dad3998827fdfb1d78c79082d2dc290f 223 Pfam PF02080 TrkA-C domain 149 216 3.0E-11 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 DC74_RS29230 dad3998827fdfb1d78c79082d2dc290f 223 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 3.0E-7 T 23-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 DC74_RS29230 dad3998827fdfb1d78c79082d2dc290f 223 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 3.0E-7 T 23-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 DC74_RS29230 dad3998827fdfb1d78c79082d2dc290f 223 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 3.0E-7 T 23-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 DC74_RS29230 dad3998827fdfb1d78c79082d2dc290f 223 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 3.0E-7 T 23-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 DC74_RS29230 dad3998827fdfb1d78c79082d2dc290f 223 SUPERFAMILY SSF116726 133 216 3.92E-13 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 DC74_RS29230 dad3998827fdfb1d78c79082d2dc290f 223 Pfam PF02254 TrkA-N domain 3 118 2.5E-24 T 23-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 DC74_RS29230 dad3998827fdfb1d78c79082d2dc290f 223 SUPERFAMILY SSF51735 1 145 1.67E-27 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29230 dad3998827fdfb1d78c79082d2dc290f 223 Gene3D G3DSA:3.40.50.720 1 132 1.3E-29 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01905 f22067edd23e76bfb8514626c25f54a0 454 Pfam PF00668 Condensation domain 31 317 4.2E-36 T 23-04-2016 IPR001242 Condensation domain DC74_RS01905 f22067edd23e76bfb8514626c25f54a0 454 SUPERFAMILY SSF52777 211 444 7.23E-43 T 23-04-2016 DC74_RS01905 f22067edd23e76bfb8514626c25f54a0 454 PANTHER PTHR24095:SF137 34 442 6.5E-44 T 23-04-2016 DC74_RS01905 f22067edd23e76bfb8514626c25f54a0 454 Pfam PF13745 HxxPF-repeated domain 342 427 1.0E-14 T 23-04-2016 DC74_RS01905 f22067edd23e76bfb8514626c25f54a0 454 SUPERFAMILY SSF52777 34 202 1.11E-25 T 23-04-2016 DC74_RS01905 f22067edd23e76bfb8514626c25f54a0 454 PANTHER PTHR24095 34 442 6.5E-44 T 23-04-2016 DC74_RS00895 b2b4132bf759cd0f53ad3bd0e53dd70b 260 PANTHER PTHR10992 3 258 2.9E-50 T 23-04-2016 DC74_RS00895 b2b4132bf759cd0f53ad3bd0e53dd70b 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 2.4E-10 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS00895 b2b4132bf759cd0f53ad3bd0e53dd70b 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 2.4E-10 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS00895 b2b4132bf759cd0f53ad3bd0e53dd70b 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.4E-10 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS00895 b2b4132bf759cd0f53ad3bd0e53dd70b 260 Pfam PF08386 TAP-like protein 198 257 3.9E-5 T 23-04-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal DC74_RS00895 b2b4132bf759cd0f53ad3bd0e53dd70b 260 Pfam PF00561 alpha/beta hydrolase fold 21 140 6.4E-20 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS00895 b2b4132bf759cd0f53ad3bd0e53dd70b 260 Gene3D G3DSA:3.40.50.1820 1 258 2.1E-60 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS00895 b2b4132bf759cd0f53ad3bd0e53dd70b 260 SUPERFAMILY SSF53474 1 257 1.86E-60 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 Pfam PF00561 alpha/beta hydrolase fold 44 263 7.1E-18 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 SUPERFAMILY SSF53474 12 207 2.32E-25 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 136 150 2.7E-9 T 23-04-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 46 54 2.7E-9 T 23-04-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 77 88 2.7E-9 T 23-04-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 Gene3D G3DSA:3.40.50.1820 10 239 3.9E-52 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 Gene3D G3DSA:3.40.50.1820 303 415 3.9E-52 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 PANTHER PTHR10992 111 207 4.4E-103 T 23-04-2016 DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 PANTHER PTHR10992 9 92 4.4E-103 T 23-04-2016 DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 PANTHER PTHR10992 308 419 4.4E-103 T 23-04-2016 DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 PANTHER PTHR10992:SF749 111 207 4.4E-103 T 23-04-2016 DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 PANTHER PTHR10992:SF749 9 92 4.4E-103 T 23-04-2016 DC74_RS35220 c65c27edb7b45cbf2ffaf11273ce23c7 421 PANTHER PTHR10992:SF749 308 419 4.4E-103 T 23-04-2016 DC74_RS11870 ff2dcbb52cbe1bd426be941e4f222fae 137 Pfam PF00355 Rieske [2Fe-2S] domain 46 126 1.9E-14 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS11870 ff2dcbb52cbe1bd426be941e4f222fae 137 Gene3D G3DSA:2.102.10.10 4 135 7.8E-27 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS11870 ff2dcbb52cbe1bd426be941e4f222fae 137 PANTHER PTHR21496:SF11 4 134 5.8E-14 T 23-04-2016 DC74_RS11870 ff2dcbb52cbe1bd426be941e4f222fae 137 PRINTS PR00162 Rieske 2Fe-2S subunit signature 110 122 1.8E-6 T 23-04-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 DC74_RS11870 ff2dcbb52cbe1bd426be941e4f222fae 137 PRINTS PR00162 Rieske 2Fe-2S subunit signature 77 88 1.8E-6 T 23-04-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 DC74_RS11870 ff2dcbb52cbe1bd426be941e4f222fae 137 PRINTS PR00162 Rieske 2Fe-2S subunit signature 97 109 1.8E-6 T 23-04-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 DC74_RS11870 ff2dcbb52cbe1bd426be941e4f222fae 137 PANTHER PTHR21496 4 134 5.8E-14 T 23-04-2016 DC74_RS11870 ff2dcbb52cbe1bd426be941e4f222fae 137 SUPERFAMILY SSF50022 39 136 1.17E-23 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS13635 7d12b29bbfde864dc724ca92751f5c06 356 Gene3D G3DSA:1.50.10.20 23 202 5.8E-13 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS13635 7d12b29bbfde864dc724ca92751f5c06 356 SUPERFAMILY SSF48208 34 333 6.12E-39 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 DC74_RS10490 6279538e3308a5a48b125fc94dd41b3c 327 Pfam PF00248 Aldo/keto reductase family 16 311 1.4E-56 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS10490 6279538e3308a5a48b125fc94dd41b3c 327 SUPERFAMILY SSF51430 1 317 8.51E-85 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS10490 6279538e3308a5a48b125fc94dd41b3c 327 Gene3D G3DSA:3.20.20.100 1 315 2.4E-86 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS10490 6279538e3308a5a48b125fc94dd41b3c 327 PANTHER PTHR11732:SF191 1 325 3.5E-125 T 23-04-2016 DC74_RS10490 6279538e3308a5a48b125fc94dd41b3c 327 PANTHER PTHR11732 1 325 3.5E-125 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 220 1.4E-21 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 SUPERFAMILY SSF46894 162 225 4.08E-23 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 180 207 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 PANTHER PTHR26402:SF151 19 225 1.5E-91 T 23-04-2016 DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 SMART SM00421 163 220 2.3E-28 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 PANTHER PTHR26402 19 225 1.5E-91 T 23-04-2016 DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 Pfam PF00072 Response regulator receiver domain 21 132 1.7E-31 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 SMART SM00448 19 132 2.5E-35 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 Gene3D G3DSA:1.10.10.10 166 225 1.1E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 SUPERFAMILY SSF52172 19 148 7.26E-38 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 Gene3D G3DSA:3.40.50.2300 18 165 1.1E-44 T 23-04-2016 DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 5.7E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 5.7E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS11265 3cff2b3896949b72730620be57b1bd31 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 5.7E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS04130 e96cdb8d751de63d4a12969304467af8 230 Pfam PF00557 Metallopeptidase family M24 14 176 9.2E-19 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS04130 e96cdb8d751de63d4a12969304467af8 230 SUPERFAMILY SSF55920 9 177 1.23E-20 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS04130 e96cdb8d751de63d4a12969304467af8 230 Gene3D G3DSA:3.90.230.10 7 177 1.6E-16 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS06205 ba64ea256107bb0b3512973b32d9adfb 311 Pfam PF13354 Beta-lactamase enzyme family 43 279 6.3E-43 T 23-04-2016 DC74_RS06205 ba64ea256107bb0b3512973b32d9adfb 311 PANTHER PTHR35333 12 311 5.7E-33 T 23-04-2016 DC74_RS06205 ba64ea256107bb0b3512973b32d9adfb 311 Gene3D G3DSA:3.40.710.10 20 287 1.2E-42 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS06205 ba64ea256107bb0b3512973b32d9adfb 311 SUPERFAMILY SSF56601 21 166 9.82E-37 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS06205 ba64ea256107bb0b3512973b32d9adfb 311 SUPERFAMILY SSF56601 196 303 9.82E-37 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS13735 def103a65460105402fd608e94ffdd68 356 Pfam PF10092 Uncharacterized protein conserved in bacteria (DUF2330) 13 240 1.4E-70 T 23-04-2016 IPR019283 Protein of unknown function DUF2330 DC74_RS28370 6a2a4d0ee0197483d717ae94dfce7e41 485 SUPERFAMILY SSF53720 9 480 6.41E-131 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS28370 6a2a4d0ee0197483d717ae94dfce7e41 485 PANTHER PTHR11699:SF108 21 480 2.9E-232 T 23-04-2016 DC74_RS28370 6a2a4d0ee0197483d717ae94dfce7e41 485 Gene3D G3DSA:3.40.309.10 270 454 1.1E-56 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS28370 6a2a4d0ee0197483d717ae94dfce7e41 485 Pfam PF00171 Aldehyde dehydrogenase family 19 475 1.7E-130 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS28370 6a2a4d0ee0197483d717ae94dfce7e41 485 Gene3D G3DSA:3.40.605.10 11 269 7.7E-68 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS28370 6a2a4d0ee0197483d717ae94dfce7e41 485 PANTHER PTHR11699 21 480 2.9E-232 T 23-04-2016 DC74_RS19140 529b331f58b3a442f7b746dda4b0943b 489 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 82 5.5E-18 T 23-04-2016 IPR024962 YukD-like DC74_RS19140 529b331f58b3a442f7b746dda4b0943b 489 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 11 484 2.0E-49 T 23-04-2016 IPR006707 Type VII secretion system membrane protein EccD DC74_RS19140 529b331f58b3a442f7b746dda4b0943b 489 PIRSF PIRSF017804 1 488 2.5E-105 T 23-04-2016 IPR006707 Type VII secretion system membrane protein EccD DC74_RS21090 f1f20c126c74ba3c87b284231e1ff6eb 366 PANTHER PTHR24220 18 239 2.3E-133 T 23-04-2016 DC74_RS21090 f1f20c126c74ba3c87b284231e1ff6eb 366 Pfam PF00005 ABC transporter 32 175 8.8E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS21090 f1f20c126c74ba3c87b284231e1ff6eb 366 SMART SM00382 40 223 9.1E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS21090 f1f20c126c74ba3c87b284231e1ff6eb 366 Gene3D G3DSA:3.40.50.300 15 236 5.2E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS21090 f1f20c126c74ba3c87b284231e1ff6eb 366 PANTHER PTHR24220:SF563 18 239 2.3E-133 T 23-04-2016 DC74_RS21090 f1f20c126c74ba3c87b284231e1ff6eb 366 PANTHER PTHR24220 292 304 2.3E-133 T 23-04-2016 DC74_RS21090 f1f20c126c74ba3c87b284231e1ff6eb 366 PANTHER PTHR24220:SF563 292 304 2.3E-133 T 23-04-2016 DC74_RS21090 f1f20c126c74ba3c87b284231e1ff6eb 366 SUPERFAMILY SSF52540 22 225 1.74E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35900 65c408c97611bafe357861997e2ce8ea 368 PIRSF PIRSF005644 33 368 1.8E-120 T 23-04-2016 IPR011854 Hydrogenase expression/formation protein HypE DC74_RS35900 65c408c97611bafe357861997e2ce8ea 368 Pfam PF00586 AIR synthase related protein, N-terminal domain 71 182 8.1E-13 T 23-04-2016 IPR016188 PurM-like, N-terminal domain DC74_RS35900 65c408c97611bafe357861997e2ce8ea 368 Gene3D G3DSA:3.30.1330.10 51 184 5.7E-20 T 23-04-2016 IPR016188 PurM-like, N-terminal domain DC74_RS35900 65c408c97611bafe357861997e2ce8ea 368 PANTHER PTHR30303 33 368 3.1E-144 T 23-04-2016 DC74_RS35900 65c408c97611bafe357861997e2ce8ea 368 SUPERFAMILY SSF55326 37 185 2.62E-27 T 23-04-2016 DC74_RS35900 65c408c97611bafe357861997e2ce8ea 368 Gene3D G3DSA:3.90.650.10 193 351 4.0E-25 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS35900 65c408c97611bafe357861997e2ce8ea 368 Pfam PF02769 AIR synthase related protein, C-terminal domain 195 340 3.4E-27 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS35900 65c408c97611bafe357861997e2ce8ea 368 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 37 368 3.5E-135 T 23-04-2016 IPR011854 Hydrogenase expression/formation protein HypE DC74_RS35900 65c408c97611bafe357861997e2ce8ea 368 SUPERFAMILY SSF56042 189 364 1.29E-45 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain DC74_RS35900 65c408c97611bafe357861997e2ce8ea 368 PANTHER PTHR30303:SF0 33 368 3.1E-144 T 23-04-2016 DC74_RS26920 e044f8f96c02598935f233fcca125956 83 Hamap MF_01396 ATP synthase subunit c [atpH]. 17 83 12.401 T 23-04-2016 DC74_RS26920 e044f8f96c02598935f233fcca125956 83 PRINTS PR00124 ATP synthase C subunit signature 41 56 3.7E-16 T 23-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 DC74_RS26920 e044f8f96c02598935f233fcca125956 83 PRINTS PR00124 ATP synthase C subunit signature 58 83 3.7E-16 T 23-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 DC74_RS26920 e044f8f96c02598935f233fcca125956 83 PRINTS PR00124 ATP synthase C subunit signature 20 39 3.7E-16 T 23-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 DC74_RS26920 e044f8f96c02598935f233fcca125956 83 Pfam PF00137 ATP synthase subunit C 21 81 9.1E-12 T 23-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 DC74_RS26920 e044f8f96c02598935f233fcca125956 83 SUPERFAMILY SSF81333 21 82 7.06E-17 T 23-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 DC74_RS26920 e044f8f96c02598935f233fcca125956 83 ProSitePatterns PS00605 ATP synthase c subunit signature. 48 69 - T 23-04-2016 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site DC74_RS26920 e044f8f96c02598935f233fcca125956 83 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 28 80 6.5E-13 T 23-04-2016 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 DC74_RS26920 e044f8f96c02598935f233fcca125956 83 PANTHER PTHR10031 23 80 2.5E-15 T 23-04-2016 DC74_RS26920 e044f8f96c02598935f233fcca125956 83 Gene3D G3DSA:1.20.20.10 21 81 4.9E-20 T 23-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 DC74_RS19145 f85fb6f9ca1146ed18a24b13707c9af2 525 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 521 1.5E-78 T 23-04-2016 IPR007795 Type VII secretion system EccB DC74_RS19145 f85fb6f9ca1146ed18a24b13707c9af2 525 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 4 466 1.4E-56 T 23-04-2016 IPR007795 Type VII secretion system EccB DC74_RS19145 f85fb6f9ca1146ed18a24b13707c9af2 525 PANTHER PTHR40765 1 466 7.1E-88 T 23-04-2016 DC74_RS19145 f85fb6f9ca1146ed18a24b13707c9af2 525 PANTHER PTHR40765 497 525 7.1E-88 T 23-04-2016 DC74_RS19145 f85fb6f9ca1146ed18a24b13707c9af2 525 PANTHER PTHR40765:SF1 1 466 7.1E-88 T 23-04-2016 DC74_RS19145 f85fb6f9ca1146ed18a24b13707c9af2 525 PANTHER PTHR40765:SF1 497 525 7.1E-88 T 23-04-2016 DC74_RS40615 6ef6dcd5726863c528b20d4836f3219e 177 ProSitePatterns PS00893 Nudix box signature. 52 73 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS40615 6ef6dcd5726863c528b20d4836f3219e 177 PANTHER PTHR22769 32 74 6.2E-14 T 23-04-2016 DC74_RS40615 6ef6dcd5726863c528b20d4836f3219e 177 PANTHER PTHR22769 93 176 6.2E-14 T 23-04-2016 DC74_RS40615 6ef6dcd5726863c528b20d4836f3219e 177 Gene3D G3DSA:3.90.79.10 26 166 1.5E-25 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS40615 6ef6dcd5726863c528b20d4836f3219e 177 PRINTS PR00502 NUDIX hydrolase family signature 61 76 6.1E-5 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS40615 6ef6dcd5726863c528b20d4836f3219e 177 PRINTS PR00502 NUDIX hydrolase family signature 47 61 6.1E-5 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS40615 6ef6dcd5726863c528b20d4836f3219e 177 Pfam PF00293 NUDIX domain 32 153 7.9E-17 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS40615 6ef6dcd5726863c528b20d4836f3219e 177 SUPERFAMILY SSF55811 23 166 5.55E-24 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS19320 b1e7e0799f380aba0b54eb827206d7ea 231 SUPERFAMILY SSF53254 12 203 3.8E-36 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS19320 b1e7e0799f380aba0b54eb827206d7ea 231 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 14 198 3.0E-35 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS19320 b1e7e0799f380aba0b54eb827206d7ea 231 PANTHER PTHR23029 11 212 7.5E-94 T 23-04-2016 DC74_RS19320 b1e7e0799f380aba0b54eb827206d7ea 231 SMART SM00855 13 165 3.9E-16 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS19320 b1e7e0799f380aba0b54eb827206d7ea 231 PANTHER PTHR23029:SF35 11 212 7.5E-94 T 23-04-2016 DC74_RS19320 b1e7e0799f380aba0b54eb827206d7ea 231 Gene3D G3DSA:3.40.50.1240 14 199 1.4E-29 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS40150 74eec07bc02aedf3096dd38a887abf1f 305 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 11 159 4.0E-33 T 23-04-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase DC74_RS40150 74eec07bc02aedf3096dd38a887abf1f 305 PANTHER PTHR30244:SF16 21 155 4.0E-18 T 23-04-2016 DC74_RS40150 74eec07bc02aedf3096dd38a887abf1f 305 Gene3D G3DSA:3.40.640.10 4 167 3.2E-36 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS40150 74eec07bc02aedf3096dd38a887abf1f 305 SUPERFAMILY SSF53383 8 278 9.68E-35 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS40150 74eec07bc02aedf3096dd38a887abf1f 305 PANTHER PTHR30244 21 155 4.0E-18 T 23-04-2016 DC74_RS15365 7c2b85f54b9748ddf4b40956ecfced33 409 Pfam PF13527 Acetyltransferase (GNAT) domain 4 130 6.4E-32 T 23-04-2016 DC74_RS15365 7c2b85f54b9748ddf4b40956ecfced33 409 Gene3D G3DSA:3.40.630.30 128 288 2.2E-16 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS15365 7c2b85f54b9748ddf4b40956ecfced33 409 Gene3D G3DSA:3.40.630.30 1 127 4.2E-23 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS15365 7c2b85f54b9748ddf4b40956ecfced33 409 PANTHER PTHR37817:SF1 1 409 1.8E-82 T 23-04-2016 DC74_RS15365 7c2b85f54b9748ddf4b40956ecfced33 409 PANTHER PTHR37817 1 409 1.8E-82 T 23-04-2016 DC74_RS15365 7c2b85f54b9748ddf4b40956ecfced33 409 SUPERFAMILY SSF55729 4 302 6.76E-57 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS15365 7c2b85f54b9748ddf4b40956ecfced33 409 SUPERFAMILY SSF55718 304 409 6.28E-26 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS15365 7c2b85f54b9748ddf4b40956ecfced33 409 Pfam PF13530 Sterol carrier protein domain 180 406 9.2E-49 T 23-04-2016 IPR025559 Enhanced intracellular survival protein domain DC74_RS15365 7c2b85f54b9748ddf4b40956ecfced33 409 Gene3D G3DSA:3.30.1050.10 289 397 9.6E-25 T 23-04-2016 IPR003033 SCP2 sterol-binding domain DC74_RS15950 beeed8af950ebca0c9a624d9b778de3f 206 Hamap MF_00045 Oligoribonuclease [orn]. 1 179 37.926 T 23-04-2016 IPR022894 Oligoribonuclease GO:0016788 DC74_RS15950 beeed8af950ebca0c9a624d9b778de3f 206 Pfam PF00929 Exonuclease 6 168 6.4E-25 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III DC74_RS15950 beeed8af950ebca0c9a624d9b778de3f 206 SUPERFAMILY SSF53098 3 177 6.6E-42 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS15950 beeed8af950ebca0c9a624d9b778de3f 206 PANTHER PTHR11046:SF5 1 193 9.8E-128 T 23-04-2016 DC74_RS15950 beeed8af950ebca0c9a624d9b778de3f 206 Gene3D G3DSA:3.30.420.10 1 177 2.3E-67 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS15950 beeed8af950ebca0c9a624d9b778de3f 206 SMART SM00479 4 178 7.7E-23 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III DC74_RS15950 beeed8af950ebca0c9a624d9b778de3f 206 PANTHER PTHR11046 1 193 9.8E-128 T 23-04-2016 DC74_RS36455 661eebf0ea8704e7e24f4d6c9df735a1 167 Pfam PF07883 Cupin domain 78 150 4.9E-9 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS36455 661eebf0ea8704e7e24f4d6c9df735a1 167 SUPERFAMILY SSF51182 19 165 1.7E-20 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS36455 661eebf0ea8704e7e24f4d6c9df735a1 167 Gene3D G3DSA:2.60.120.10 49 165 8.6E-26 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS29965 cc39a4b7f946bc4d53a6668c9cab2408 184 Pfam PF00498 FHA domain 106 169 4.4E-17 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS29965 cc39a4b7f946bc4d53a6668c9cab2408 184 PANTHER PTHR15715 104 169 1.6E-14 T 23-04-2016 DC74_RS29965 cc39a4b7f946bc4d53a6668c9cab2408 184 Gene3D G3DSA:2.60.200.20 104 176 1.6E-23 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS29965 cc39a4b7f946bc4d53a6668c9cab2408 184 SUPERFAMILY SSF49879 84 175 4.26E-24 T 23-04-2016 IPR008984 SMAD/FHA domain GO:0005515 DC74_RS29965 cc39a4b7f946bc4d53a6668c9cab2408 184 Pfam PF08044 Domain of unknown function (DUF1707) 9 59 5.6E-14 T 23-04-2016 IPR012551 Protein of unknown function DUF1707 DC74_RS29965 cc39a4b7f946bc4d53a6668c9cab2408 184 SMART SM00240 104 154 8.7E-14 T 23-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DC74_RS11680 b91b589961582558bb48a8e64e2627bd 612 PANTHER PTHR33607 26 610 2.1E-170 T 23-04-2016 DC74_RS11680 b91b589961582558bb48a8e64e2627bd 612 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 309 603 3.6E-13 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS11680 b91b589961582558bb48a8e64e2627bd 612 PANTHER PTHR33607:SF1 26 610 2.1E-170 T 23-04-2016 DC74_RS11680 b91b589961582558bb48a8e64e2627bd 612 Gene3D G3DSA:3.60.10.10 306 610 2.2E-33 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS11680 b91b589961582558bb48a8e64e2627bd 612 SUPERFAMILY SSF56219 307 610 2.45E-29 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS01180 6e846969cf6610f8c741b80020d58ae2 153 Gene3D G3DSA:2.60.120.10 4 140 2.0E-15 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS01180 6e846969cf6610f8c741b80020d58ae2 153 Pfam PF00027 Cyclic nucleotide-binding domain 25 109 1.8E-8 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS01180 6e846969cf6610f8c741b80020d58ae2 153 SUPERFAMILY SSF51206 3 141 9.3E-21 T 23-04-2016 IPR018490 Cyclic nucleotide-binding-like DC74_RS01180 6e846969cf6610f8c741b80020d58ae2 153 PANTHER PTHR24567 5 133 1.8E-13 T 23-04-2016 DC74_RS01180 6e846969cf6610f8c741b80020d58ae2 153 SMART SM00100 6 127 2.1E-9 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain DC74_RS33415 eaa9652ec754a078fc0f342edaff2c1f 346 SUPERFAMILY SSF69304 130 330 8.24E-11 T 23-04-2016 DC74_RS33415 eaa9652ec754a078fc0f342edaff2c1f 346 Pfam PF07676 WD40-like Beta Propeller Repeat 249 262 0.0067 T 23-04-2016 IPR011659 WD40-like Beta Propeller DC74_RS33415 eaa9652ec754a078fc0f342edaff2c1f 346 Gene3D G3DSA:2.120.10.60 255 331 9.5E-8 T 23-04-2016 DC74_RS33415 eaa9652ec754a078fc0f342edaff2c1f 346 Gene3D G3DSA:2.130.10.10 55 89 9.6E-7 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS33415 eaa9652ec754a078fc0f342edaff2c1f 346 Gene3D G3DSA:2.130.10.10 141 254 9.6E-7 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS32410 3e49ad05946f5c086f4b2b95bb32254e 213 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 2.4E-51 T 23-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 DC74_RS32410 3e49ad05946f5c086f4b2b95bb32254e 213 PANTHER PTHR21047 3 188 1.5E-41 T 23-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 DC74_RS32410 3e49ad05946f5c086f4b2b95bb32254e 213 SUPERFAMILY SSF51182 2 197 2.8E-62 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS32410 3e49ad05946f5c086f4b2b95bb32254e 213 Gene3D G3DSA:2.60.120.10 2 191 1.8E-57 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS32410 3e49ad05946f5c086f4b2b95bb32254e 213 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 198 5.0E-56 T 23-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 DC74_RS21830 f98bf9a9fcb56d1a0ca21e763b1b80f9 279 Gene3D G3DSA:3.40.50.20 6 96 1.4E-6 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS21830 f98bf9a9fcb56d1a0ca21e763b1b80f9 279 Gene3D G3DSA:3.30.1490.20 97 170 4.0E-8 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 DC74_RS21830 f98bf9a9fcb56d1a0ca21e763b1b80f9 279 SUPERFAMILY SSF56059 83 270 6.36E-21 T 23-04-2016 DC74_RS12855 b5ace6c75270ec2ec3cf25eb73305db1 311 SUPERFAMILY SSF56563 11 230 6.8E-11 T 23-04-2016 DC74_RS32625 d8d891752d4685348d6c9c1392bb99df 238 SUPERFAMILY SSF52402 13 230 5.29E-59 T 23-04-2016 DC74_RS32625 d8d891752d4685348d6c9c1392bb99df 238 PANTHER PTHR11587 12 228 7.3E-57 T 23-04-2016 DC74_RS32625 d8d891752d4685348d6c9c1392bb99df 238 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 13 213 1.4E-53 T 23-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 DC74_RS32625 d8d891752d4685348d6c9c1392bb99df 238 PANTHER PTHR11587:SF3 12 228 7.3E-57 T 23-04-2016 DC74_RS32625 d8d891752d4685348d6c9c1392bb99df 238 Gene3D G3DSA:3.40.50.620 13 231 5.6E-67 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS32625 d8d891752d4685348d6c9c1392bb99df 238 PIRSF PIRSF006293 11 232 4.6E-68 T 23-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 DC74_RS32625 d8d891752d4685348d6c9c1392bb99df 238 Pfam PF06508 Queuosine biosynthesis protein QueC 12 220 3.6E-58 T 23-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 DC74_RS32625 d8d891752d4685348d6c9c1392bb99df 238 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 11 226 47.311 T 23-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 DC74_RS28150 36d0130e94b28ec5fd1f258c5887888a 242 Gene3D G3DSA:2.10.109.10 139 194 1.3E-29 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain DC74_RS28150 36d0130e94b28ec5fd1f258c5887888a 242 Gene3D G3DSA:2.10.109.10 41 101 1.3E-29 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain DC74_RS28150 36d0130e94b28ec5fd1f258c5887888a 242 Pfam PF00717 Peptidase S24-like 47 105 7.9E-14 T 23-04-2016 IPR019759 Peptidase S24/S26A/S26B DC74_RS28150 36d0130e94b28ec5fd1f258c5887888a 242 SUPERFAMILY SSF51306 42 191 2.93E-39 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C DC74_RS28150 36d0130e94b28ec5fd1f258c5887888a 242 PANTHER PTHR12383:SF14 14 202 3.4E-39 T 23-04-2016 DC74_RS28150 36d0130e94b28ec5fd1f258c5887888a 242 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 27 186 1.1E-37 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28150 36d0130e94b28ec5fd1f258c5887888a 242 PANTHER PTHR12383 14 202 3.4E-39 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28150 36d0130e94b28ec5fd1f258c5887888a 242 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 91 103 1.2E-19 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28150 36d0130e94b28ec5fd1f258c5887888a 242 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 139 158 1.2E-19 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS28150 36d0130e94b28ec5fd1f258c5887888a 242 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 41 57 1.2E-19 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 DC74_RS29195 4384ba32108b8b1fad22c0fd6c95a0c9 220 Pfam PF02669 K+-transporting ATPase, c chain 13 213 5.2E-69 T 23-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 DC74_RS29195 4384ba32108b8b1fad22c0fd6c95a0c9 220 PANTHER PTHR30042 6 216 9.6E-81 T 23-04-2016 DC74_RS29195 4384ba32108b8b1fad22c0fd6c95a0c9 220 PIRSF PIRSF001296 8 219 5.0E-73 T 23-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 DC74_RS29195 4384ba32108b8b1fad22c0fd6c95a0c9 220 PANTHER PTHR30042:SF2 6 216 9.6E-81 T 23-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 DC74_RS29195 4384ba32108b8b1fad22c0fd6c95a0c9 220 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 9 215 33.777 T 23-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 DC74_RS29195 4384ba32108b8b1fad22c0fd6c95a0c9 220 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 12 213 6.8E-54 T 23-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 DC74_RS03910 37de0894543d845aaae3ddfd39866327 192 PANTHER PTHR30055 2 189 2.2E-59 T 23-04-2016 DC74_RS03910 37de0894543d845aaae3ddfd39866327 192 SUPERFAMILY SSF48498 84 189 4.84E-13 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS03910 37de0894543d845aaae3ddfd39866327 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 64 3.0E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03910 37de0894543d845aaae3ddfd39866327 192 SUPERFAMILY SSF46689 10 78 3.54E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03910 37de0894543d845aaae3ddfd39866327 192 Gene3D G3DSA:1.10.357.10 8 189 6.1E-36 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS03910 37de0894543d845aaae3ddfd39866327 192 PANTHER PTHR30055:SF49 2 189 2.2E-59 T 23-04-2016 DC74_RS22075 4142a0f3f5ee2abb5980792faaa79d70 152 PANTHER PTHR41553 7 149 9.0E-28 T 23-04-2016 DC74_RS22075 4142a0f3f5ee2abb5980792faaa79d70 152 PANTHER PTHR41553:SF1 7 149 9.0E-28 T 23-04-2016 DC74_RS22075 4142a0f3f5ee2abb5980792faaa79d70 152 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 13 127 6.4E-33 T 23-04-2016 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III DC74_RS22075 4142a0f3f5ee2abb5980792faaa79d70 152 Gene3D G3DSA:1.20.1250.20 42 109 8.7E-4 T 23-04-2016 DC74_RS22075 4142a0f3f5ee2abb5980792faaa79d70 152 SUPERFAMILY SSF103473 43 108 9.94E-5 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS04860 40f822212f5d05d260568ec5422893f6 149 SUPERFAMILY SSF46785 21 142 5.73E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04860 40f822212f5d05d260568ec5422893f6 149 SMART SM00347 31 130 3.9E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS04860 40f822212f5d05d260568ec5422893f6 149 PANTHER PTHR33164 39 143 1.4E-14 T 23-04-2016 DC74_RS04860 40f822212f5d05d260568ec5422893f6 149 Pfam PF12802 MarR family 38 94 2.0E-11 T 23-04-2016 DC74_RS04860 40f822212f5d05d260568ec5422893f6 149 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 103 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS04860 40f822212f5d05d260568ec5422893f6 149 Gene3D G3DSA:1.10.10.10 11 142 8.6E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04860 40f822212f5d05d260568ec5422893f6 149 PANTHER PTHR33164:SF16 39 143 1.4E-14 T 23-04-2016 DC74_RS27715 ac6f92076ab8980a83d387dcc5bfa9e8 408 Gene3D G3DSA:3.40.710.10 45 365 1.4E-75 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS27715 ac6f92076ab8980a83d387dcc5bfa9e8 408 SUPERFAMILY SSF56601 45 378 4.54E-78 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS27715 ac6f92076ab8980a83d387dcc5bfa9e8 408 Pfam PF00144 Beta-lactamase 55 355 7.0E-59 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS27715 ac6f92076ab8980a83d387dcc5bfa9e8 408 PANTHER PTHR22935 24 389 3.9E-64 T 23-04-2016 DC74_RS40005 d66cdd45f88585a4b01d2db955cc2d6f 207 SUPERFAMILY SSF53335 2 131 1.58E-19 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40005 d66cdd45f88585a4b01d2db955cc2d6f 207 Gene3D G3DSA:3.40.50.150 2 155 6.3E-17 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40005 d66cdd45f88585a4b01d2db955cc2d6f 207 Pfam PF13489 Methyltransferase domain 35 85 1.4E-11 T 23-04-2016 DC74_RS12335 1dac53de19ebffd8d257810e35839543 210 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 5 203 1.3E-79 T 23-04-2016 IPR017519 Conserved hypothetical protein CHP03085 DC74_RS12335 1dac53de19ebffd8d257810e35839543 210 SUPERFAMILY SSF109854 12 114 2.75E-6 T 23-04-2016 DC74_RS12335 1dac53de19ebffd8d257810e35839543 210 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 5 185 3.4E-39 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS29510 be570c64a9c29aeb855999f9d05cfc52 439 Gene3D G3DSA:1.20.1250.20 21 211 6.1E-21 T 23-04-2016 DC74_RS29510 be570c64a9c29aeb855999f9d05cfc52 439 Pfam PF07690 Major Facilitator Superfamily 31 367 1.1E-27 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS29510 be570c64a9c29aeb855999f9d05cfc52 439 Gene3D G3DSA:1.20.1250.20 237 405 7.3E-18 T 23-04-2016 DC74_RS29510 be570c64a9c29aeb855999f9d05cfc52 439 SUPERFAMILY SSF103473 21 411 4.71E-49 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS29510 be570c64a9c29aeb855999f9d05cfc52 439 PANTHER PTHR23513 6 437 5.7E-55 T 23-04-2016 DC74_RS34375 59890e8e22b52608959e87701db9562d 215 PANTHER PTHR30055:SF92 3 199 1.4E-46 T 23-04-2016 DC74_RS34375 59890e8e22b52608959e87701db9562d 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS34375 59890e8e22b52608959e87701db9562d 215 PANTHER PTHR30055 3 199 1.4E-46 T 23-04-2016 DC74_RS34375 59890e8e22b52608959e87701db9562d 215 SUPERFAMILY SSF46689 12 84 7.18E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS34375 59890e8e22b52608959e87701db9562d 215 Gene3D G3DSA:1.10.357.10 17 187 7.9E-28 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS34375 59890e8e22b52608959e87701db9562d 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 4.3E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34375 59890e8e22b52608959e87701db9562d 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.3E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS34375 59890e8e22b52608959e87701db9562d 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 4.9E-16 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS14820 df1cdac490da64854af4f97c0f2b00ba 284 Gene3D G3DSA:1.10.260.40 1 73 3.8E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS14820 df1cdac490da64854af4f97c0f2b00ba 284 Pfam PF13560 Helix-turn-helix domain 1 79 3.4E-15 T 23-04-2016 DC74_RS14820 df1cdac490da64854af4f97c0f2b00ba 284 PANTHER PTHR35010:SF3 1 278 1.5E-130 T 23-04-2016 DC74_RS14820 df1cdac490da64854af4f97c0f2b00ba 284 PANTHER PTHR35010 1 278 1.5E-130 T 23-04-2016 DC74_RS14820 df1cdac490da64854af4f97c0f2b00ba 284 SMART SM00530 4 76 3.1E-4 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS33325 ee5a68d2d72eb28fb266eb521077b772 403 PANTHER PTHR15032 22 365 3.4E-106 T 23-04-2016 DC74_RS33325 ee5a68d2d72eb28fb266eb521077b772 403 Pfam PF12706 Beta-lactamase superfamily domain 114 313 2.6E-48 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS33325 ee5a68d2d72eb28fb266eb521077b772 403 Gene3D G3DSA:3.60.15.10 87 363 9.2E-101 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS33325 ee5a68d2d72eb28fb266eb521077b772 403 SUPERFAMILY SSF56281 96 173 2.62E-35 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS33325 ee5a68d2d72eb28fb266eb521077b772 403 SUPERFAMILY SSF56281 200 351 2.62E-35 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS33325 ee5a68d2d72eb28fb266eb521077b772 403 PANTHER PTHR15032:SF4 22 365 3.4E-106 T 23-04-2016 DC74_RS37685 73b70f7582db383c221233779e797394 229 PANTHER PTHR40045 16 218 1.4E-21 T 23-04-2016 DC74_RS37685 73b70f7582db383c221233779e797394 229 Pfam PF08892 YqcI/YcgG family 10 213 2.5E-52 T 23-04-2016 IPR014988 Uncharacterised protein family, YqcI/YcgG DC74_RS32735 b564e79a0343efb04d4888c804684384 309 PANTHER PTHR30346 1 306 5.1E-118 T 23-04-2016 DC74_RS32735 b564e79a0343efb04d4888c804684384 309 SUPERFAMILY SSF46785 1 87 6.76E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32735 b564e79a0343efb04d4888c804684384 309 Gene3D G3DSA:3.40.190.10 102 171 5.2E-15 T 23-04-2016 DC74_RS32735 b564e79a0343efb04d4888c804684384 309 Pfam PF03466 LysR substrate binding domain 93 286 6.9E-34 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS32735 b564e79a0343efb04d4888c804684384 309 Gene3D G3DSA:1.10.10.10 1 87 8.1E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS32735 b564e79a0343efb04d4888c804684384 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.3E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS32735 b564e79a0343efb04d4888c804684384 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.3E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS32735 b564e79a0343efb04d4888c804684384 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.3E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS32735 b564e79a0343efb04d4888c804684384 309 Gene3D G3DSA:3.40.190.10 172 256 8.2E-19 T 23-04-2016 DC74_RS32735 b564e79a0343efb04d4888c804684384 309 PANTHER PTHR30346:SF8 1 306 5.1E-118 T 23-04-2016 DC74_RS32735 b564e79a0343efb04d4888c804684384 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 6.6E-20 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS32735 b564e79a0343efb04d4888c804684384 309 SUPERFAMILY SSF53850 101 288 6.36E-29 T 23-04-2016 DC74_RS00175 1f23f42b18c1bd8624730670a331fde1 146 SUPERFAMILY SSF52980 10 133 1.18E-12 T 23-04-2016 IPR011335 Restriction endonuclease type II-like DC74_RS00175 1f23f42b18c1bd8624730670a331fde1 146 Pfam PF05685 Putative restriction endonuclease 33 133 5.8E-9 T 23-04-2016 IPR008538 Domain of unknown function DUF820 DC74_RS00175 1f23f42b18c1bd8624730670a331fde1 146 Gene3D G3DSA:3.90.1570.10 32 133 2.4E-12 T 23-04-2016 IPR012296 Nuclease, putative, TT1808 DC74_RS23055 7f10783dc488a7f6f1e2f9fc9b2cad4c 394 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 393 3.5E-137 T 23-04-2016 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain DC74_RS23055 7f10783dc488a7f6f1e2f9fc9b2cad4c 394 SUPERFAMILY SSF52440 177 292 2.22E-35 T 23-04-2016 IPR016185 Pre-ATP-grasp domain DC74_RS23055 7f10783dc488a7f6f1e2f9fc9b2cad4c 394 PANTHER PTHR30094:SF0 39 394 4.3E-85 T 23-04-2016 DC74_RS23055 7f10783dc488a7f6f1e2f9fc9b2cad4c 394 PANTHER PTHR30094 39 394 4.3E-85 T 23-04-2016 DC74_RS23055 7f10783dc488a7f6f1e2f9fc9b2cad4c 394 SUPERFAMILY SSF56059 1 169 4.59E-71 T 23-04-2016 DC74_RS23055 7f10783dc488a7f6f1e2f9fc9b2cad4c 394 SUPERFAMILY SSF56059 279 391 4.59E-71 T 23-04-2016 DC74_RS15570 1f30cda9f46cd7721c71dd36b6272698 134 SUPERFAMILY SSF46458 12 132 8.63E-38 T 23-04-2016 IPR009050 Globin-like DC74_RS15570 1f30cda9f46cd7721c71dd36b6272698 134 Pfam PF01152 Bacterial-like globin 13 129 3.9E-35 T 23-04-2016 IPR001486 Truncated hemoglobin GO:0019825 DC74_RS15570 1f30cda9f46cd7721c71dd36b6272698 134 PANTHER PTHR10681 4 133 9.4E-29 T 23-04-2016 DC74_RS15570 1f30cda9f46cd7721c71dd36b6272698 134 Gene3D G3DSA:1.10.490.10 11 132 1.7E-46 T 23-04-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 DC74_RS20205 ce877408b1087d92a6c1a0307e57e2da 313 SUPERFAMILY SSF50129 1 151 8.98E-35 T 23-04-2016 IPR011032 GroES-like DC74_RS20205 ce877408b1087d92a6c1a0307e57e2da 313 SUPERFAMILY SSF51735 118 278 2.06E-27 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20205 ce877408b1087d92a6c1a0307e57e2da 313 Gene3D G3DSA:3.40.50.720 152 243 5.2E-17 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS20205 ce877408b1087d92a6c1a0307e57e2da 313 Pfam PF13602 Zinc-binding dehydrogenase 186 311 1.1E-14 T 23-04-2016 DC74_RS20205 ce877408b1087d92a6c1a0307e57e2da 313 Gene3D G3DSA:3.90.180.10 1 151 9.4E-42 T 23-04-2016 IPR011032 GroES-like DC74_RS20205 ce877408b1087d92a6c1a0307e57e2da 313 PANTHER PTHR11695:SF294 13 313 6.2E-73 T 23-04-2016 DC74_RS20205 ce877408b1087d92a6c1a0307e57e2da 313 SMART SM00829 10 311 1.0E-12 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS20205 ce877408b1087d92a6c1a0307e57e2da 313 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 92 7.2E-11 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS20205 ce877408b1087d92a6c1a0307e57e2da 313 PANTHER PTHR11695 13 313 6.2E-73 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS07685 f7409405a975a755ea7f3769435d4273 279 Pfam PF02839 Carbohydrate binding domain 234 276 1.8E-7 T 23-04-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 DC74_RS07685 f7409405a975a755ea7f3769435d4273 279 Gene3D G3DSA:2.60.130.10 61 215 4.5E-41 T 23-04-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 DC74_RS07685 f7409405a975a755ea7f3769435d4273 279 PANTHER PTHR33711 33 237 5.2E-75 T 23-04-2016 DC74_RS07685 f7409405a975a755ea7f3769435d4273 279 Pfam PF00775 Dioxygenase 69 213 2.6E-16 T 23-04-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 DC74_RS07685 f7409405a975a755ea7f3769435d4273 279 PANTHER PTHR33711:SF3 33 237 5.2E-75 T 23-04-2016 DC74_RS07685 f7409405a975a755ea7f3769435d4273 279 SUPERFAMILY SSF51055 235 277 6.15E-14 T 23-04-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 DC74_RS07685 f7409405a975a755ea7f3769435d4273 279 SUPERFAMILY SSF49482 61 215 1.02E-44 T 23-04-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 DC74_RS07685 f7409405a975a755ea7f3769435d4273 279 SMART SM00495 233 279 4.5E-10 T 23-04-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 DC74_RS07685 f7409405a975a755ea7f3769435d4273 279 Gene3D G3DSA:2.10.10.20 235 278 5.1E-22 T 23-04-2016 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 DC74_RS02250 ae294735f158b5cda473879489dcc763 67 PANTHER PTHR36923 1 64 3.6E-18 T 23-04-2016 DC74_RS02250 ae294735f158b5cda473879489dcc763 67 Gene3D G3DSA:3.30.70.20 1 65 5.6E-16 T 23-04-2016 DC74_RS02250 ae294735f158b5cda473879489dcc763 67 Pfam PF06902 Divergent 4Fe-4S mono-cluster 2 64 5.2E-12 T 23-04-2016 IPR010693 Divergent 4Fe-4S mono-cluster DC74_RS02250 ae294735f158b5cda473879489dcc763 67 SUPERFAMILY SSF54862 2 64 3.35E-11 T 23-04-2016 DC74_RS02250 ae294735f158b5cda473879489dcc763 67 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.9E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS02250 ae294735f158b5cda473879489dcc763 67 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.9E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS02250 ae294735f158b5cda473879489dcc763 67 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 1.9E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS02250 ae294735f158b5cda473879489dcc763 67 PANTHER PTHR36923:SF1 1 64 3.6E-18 T 23-04-2016 DC74_RS34005 ccc7c52a77a7546291048be29a7e05fe 594 SMART SM00382 382 568 1.1E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS34005 ccc7c52a77a7546291048be29a7e05fe 594 SUPERFAMILY SSF90123 34 345 2.88E-51 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS34005 ccc7c52a77a7546291048be29a7e05fe 594 Pfam PF00005 ABC transporter 373 522 9.1E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS34005 ccc7c52a77a7546291048be29a7e05fe 594 PANTHER PTHR24221:SF221 28 594 0.0 T 23-04-2016 DC74_RS34005 ccc7c52a77a7546291048be29a7e05fe 594 PANTHER PTHR24221 28 594 0.0 T 23-04-2016 DC74_RS34005 ccc7c52a77a7546291048be29a7e05fe 594 Gene3D G3DSA:3.40.50.300 357 587 9.6E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34005 ccc7c52a77a7546291048be29a7e05fe 594 Pfam PF00664 ABC transporter transmembrane region 45 314 5.1E-28 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS34005 ccc7c52a77a7546291048be29a7e05fe 594 SUPERFAMILY SSF52540 351 592 2.76E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34005 ccc7c52a77a7546291048be29a7e05fe 594 Gene3D G3DSA:1.20.1560.10 34 345 1.2E-50 T 23-04-2016 DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.1E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.1E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.1E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 246 1.0E-65 T 23-04-2016 DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.5E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.5E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.5E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.5E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.5E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.5E-40 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 PANTHER PTHR24322:SF639 11 193 1.8E-48 T 23-04-2016 DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 PANTHER PTHR24322 11 193 1.8E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 Gene3D G3DSA:3.40.50.720 2 248 1.4E-84 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17665 e51e24b8d83858a27c53cc454ba0d6dd 260 SUPERFAMILY SSF51735 6 247 1.75E-80 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS28155 50650b4ebec3c93d13c78fbb79407fc9 158 SUPERFAMILY SSF55811 2 126 1.76E-21 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS28155 50650b4ebec3c93d13c78fbb79407fc9 158 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS28155 50650b4ebec3c93d13c78fbb79407fc9 158 Gene3D G3DSA:3.90.79.10 2 145 2.9E-27 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS28155 50650b4ebec3c93d13c78fbb79407fc9 158 PRINTS PR00502 NUDIX hydrolase family signature 32 46 4.3E-6 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS28155 50650b4ebec3c93d13c78fbb79407fc9 158 PRINTS PR00502 NUDIX hydrolase family signature 46 61 4.3E-6 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS28155 50650b4ebec3c93d13c78fbb79407fc9 158 Pfam PF00293 NUDIX domain 6 125 5.9E-20 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS30905 7e113608cfcf6555bae35f38da932439 206 PANTHER PTHR33711:SF2 11 206 2.7E-37 T 23-04-2016 DC74_RS30905 7e113608cfcf6555bae35f38da932439 206 SUPERFAMILY SSF49482 11 192 7.85E-37 T 23-04-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 DC74_RS30905 7e113608cfcf6555bae35f38da932439 206 Gene3D G3DSA:2.60.130.10 10 203 1.8E-49 T 23-04-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 DC74_RS30905 7e113608cfcf6555bae35f38da932439 206 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 14 204 5.9E-41 T 23-04-2016 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|UniPathway: UPA00157 DC74_RS30905 7e113608cfcf6555bae35f38da932439 206 PANTHER PTHR33711 11 206 2.7E-37 T 23-04-2016 DC74_RS30905 7e113608cfcf6555bae35f38da932439 206 Pfam PF00775 Dioxygenase 42 124 1.6E-7 T 23-04-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 DC74_RS19960 1c011ae0fc4ddbe15db95ea365f454f3 756 SUPERFAMILY SSF46548 285 338 1.05E-21 T 23-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 DC74_RS19960 1c011ae0fc4ddbe15db95ea365f454f3 756 SUPERFAMILY SSF46548 376 421 1.05E-21 T 23-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 DC74_RS19960 1c011ae0fc4ddbe15db95ea365f454f3 756 PANTHER PTHR11921:SF22 97 338 1.9E-205 T 23-04-2016 DC74_RS19960 1c011ae0fc4ddbe15db95ea365f454f3 756 PANTHER PTHR11921:SF22 371 735 1.9E-205 T 23-04-2016 DC74_RS19960 1c011ae0fc4ddbe15db95ea365f454f3 756 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 302 313 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS19960 1c011ae0fc4ddbe15db95ea365f454f3 756 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 393 404 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS19960 1c011ae0fc4ddbe15db95ea365f454f3 756 Pfam PF02754 Cysteine-rich domain 616 703 4.1E-19 T 23-04-2016 IPR004017 Cysteine-rich domain DC74_RS19960 1c011ae0fc4ddbe15db95ea365f454f3 756 Pfam PF02754 Cysteine-rich domain 478 577 3.9E-13 T 23-04-2016 IPR004017 Cysteine-rich domain DC74_RS19960 1c011ae0fc4ddbe15db95ea365f454f3 756 Pfam PF13183 4Fe-4S dicluster domain 299 407 2.2E-14 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS19960 1c011ae0fc4ddbe15db95ea365f454f3 756 PANTHER PTHR11921 97 338 1.9E-205 T 23-04-2016 DC74_RS19960 1c011ae0fc4ddbe15db95ea365f454f3 756 PANTHER PTHR11921 371 735 1.9E-205 T 23-04-2016 DC74_RS19960 1c011ae0fc4ddbe15db95ea365f454f3 756 Gene3D G3DSA:1.10.1060.10 278 422 1.2E-32 T 23-04-2016 DC74_RS25725 e9078d0141d1587e8673212fb2090a60 91 SUPERFAMILY SSF56349 23 88 7.06E-18 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DC74_RS25725 e9078d0141d1587e8673212fb2090a60 91 PANTHER PTHR30349 23 90 6.3E-13 T 23-04-2016 DC74_RS25725 e9078d0141d1587e8673212fb2090a60 91 Gene3D G3DSA:1.10.443.10 11 85 2.0E-16 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS25725 e9078d0141d1587e8673212fb2090a60 91 Pfam PF00589 Phage integrase family 15 83 1.1E-11 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.01E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.01E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.01E-7 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 Gene3D G3DSA:1.10.10.10 160 212 3.6E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 PANTHER PTHR26402 6 218 9.9E-67 T 23-04-2016 DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 Pfam PF00072 Response regulator receiver domain 8 119 1.7E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 4.3E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 SUPERFAMILY SSF46894 146 212 4.76E-16 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 SUPERFAMILY SSF52172 5 137 1.14E-32 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 Gene3D G3DSA:3.40.50.2300 4 159 1.5E-36 T 23-04-2016 DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 SMART SM00448 6 119 1.1E-29 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 SMART SM00421 153 210 1.6E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS03605 053356f1894c656ee2b54b7e404af36e 218 PANTHER PTHR26402:SF564 6 218 9.9E-67 T 23-04-2016 DC74_RS05010 64c620c9908236b5bb07552f70bf367a 481 PIRSF PIRSF019251 5 479 3.5E-186 T 23-04-2016 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 DC74_RS05010 64c620c9908236b5bb07552f70bf367a 481 SMART SM00530 15 70 2.4E-14 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS05010 64c620c9908236b5bb07552f70bf367a 481 SUPERFAMILY SSF47413 13 76 6.44E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS05010 64c620c9908236b5bb07552f70bf367a 481 Pfam PF01381 Helix-turn-helix 16 69 4.8E-12 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS05010 64c620c9908236b5bb07552f70bf367a 481 Gene3D G3DSA:1.10.260.40 5 79 4.8E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS05010 64c620c9908236b5bb07552f70bf367a 481 Pfam PF06114 Domain of unknown function (DUF955) 193 317 1.6E-19 T 23-04-2016 IPR010359 HTH domain, IrrE-type DC74_RS05010 64c620c9908236b5bb07552f70bf367a 481 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 318 474 1.1E-69 T 23-04-2016 IPR018653 Domain of unknown function DUF2083,transcriptional regulator DC74_RS38455 a56926f030f07787735d54e904bd0af6 386 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 57 384 2.3E-94 T 23-04-2016 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 DC74_RS38455 a56926f030f07787735d54e904bd0af6 386 PANTHER PTHR31377:SF0 37 386 2.6E-96 T 23-04-2016 DC74_RS38455 a56926f030f07787735d54e904bd0af6 386 SUPERFAMILY SSF55909 50 385 4.82E-99 T 23-04-2016 DC74_RS38455 a56926f030f07787735d54e904bd0af6 386 Gene3D G3DSA:3.75.10.10 49 385 8.1E-106 T 23-04-2016 DC74_RS38455 a56926f030f07787735d54e904bd0af6 386 PANTHER PTHR31377 37 386 2.6E-96 T 23-04-2016 DC74_RS26150 82f1043fe5acc792c5a3fe95f7e3f4e2 392 Gene3D G3DSA:3.40.50.720 12 258 1.6E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26150 82f1043fe5acc792c5a3fe95f7e3f4e2 392 Pfam PF00581 Rhodanese-like domain 290 383 1.5E-13 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS26150 82f1043fe5acc792c5a3fe95f7e3f4e2 392 Gene3D G3DSA:3.40.250.10 274 387 1.1E-27 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS26150 82f1043fe5acc792c5a3fe95f7e3f4e2 392 PANTHER PTHR10953:SF153 1 392 9.1E-267 T 23-04-2016 DC74_RS26150 82f1043fe5acc792c5a3fe95f7e3f4e2 392 PANTHER PTHR10953 1 392 9.1E-267 T 23-04-2016 DC74_RS26150 82f1043fe5acc792c5a3fe95f7e3f4e2 392 SMART SM00450 290 387 3.1E-23 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS26150 82f1043fe5acc792c5a3fe95f7e3f4e2 392 SUPERFAMILY SSF69572 7 357 1.16E-106 T 23-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 DC74_RS26150 82f1043fe5acc792c5a3fe95f7e3f4e2 392 Pfam PF00899 ThiF family 21 254 2.2E-65 T 23-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 DC74_RS07725 318ceca67f9447ad69c4bd5c97285ab0 416 TIGRFAM TIGR02079 THD1: threonine dehydratase 9 415 2.2E-161 T 23-04-2016 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 DC74_RS07725 318ceca67f9447ad69c4bd5c97285ab0 416 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 310 1.1E-79 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS07725 318ceca67f9447ad69c4bd5c97285ab0 416 SUPERFAMILY SSF53686 10 357 4.98E-96 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS07725 318ceca67f9447ad69c4bd5c97285ab0 416 SUPERFAMILY SSF55021 333 403 7.32E-8 T 23-04-2016 DC74_RS07725 318ceca67f9447ad69c4bd5c97285ab0 416 PANTHER PTHR10314:SF30 10 362 3.1E-144 T 23-04-2016 DC74_RS07725 318ceca67f9447ad69c4bd5c97285ab0 416 PANTHER PTHR10314 10 362 3.1E-144 T 23-04-2016 DC74_RS07725 318ceca67f9447ad69c4bd5c97285ab0 416 Gene3D G3DSA:3.40.50.1100 53 140 3.0E-30 T 23-04-2016 DC74_RS07725 318ceca67f9447ad69c4bd5c97285ab0 416 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 323 414 5.8E-22 T 23-04-2016 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 DC74_RS07725 318ceca67f9447ad69c4bd5c97285ab0 416 Gene3D G3DSA:3.40.50.1100 141 328 5.6E-56 T 23-04-2016 DC74_RS21235 6d198a415ca3e3435676ceaa80080990 281 Pfam PF13349 Putative adhesin 47 277 5.0E-11 T 23-04-2016 IPR025164 Putative adhesin DC74_RS26440 03961a8c1be29bc29b824130dfb00b49 324 Gene3D G3DSA:1.10.3720.10 31 311 1.6E-57 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26440 03961a8c1be29bc29b824130dfb00b49 324 PANTHER PTHR32243:SF40 30 167 1.9E-98 T 23-04-2016 DC74_RS26440 03961a8c1be29bc29b824130dfb00b49 324 PANTHER PTHR32243:SF40 186 322 1.9E-98 T 23-04-2016 DC74_RS26440 03961a8c1be29bc29b824130dfb00b49 324 SUPERFAMILY SSF161098 31 318 6.41E-53 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS26440 03961a8c1be29bc29b824130dfb00b49 324 PANTHER PTHR32243 30 167 1.9E-98 T 23-04-2016 DC74_RS26440 03961a8c1be29bc29b824130dfb00b49 324 PANTHER PTHR32243 186 322 1.9E-98 T 23-04-2016 DC74_RS26440 03961a8c1be29bc29b824130dfb00b49 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 312 4.9E-19 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 SUPERFAMILY SSF55781 201 382 1.37E-20 T 23-04-2016 IPR029016 GAF domain-like DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 Pfam PF07730 Histidine kinase 374 436 2.1E-10 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 SMART SM00065 52 199 6.4E-14 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 SMART SM00065 220 366 7.7E-9 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 SUPERFAMILY SSF55874 483 567 2.58E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 PANTHER PTHR11347 24 367 3.6E-34 T 23-04-2016 DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 PANTHER PTHR11347 409 508 3.6E-34 T 23-04-2016 DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 SMART SM00387 479 570 0.0032 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 Pfam PF13185 GAF domain 52 190 1.3E-15 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 Pfam PF13185 GAF domain 222 357 2.2E-16 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 SUPERFAMILY SSF55781 38 216 1.92E-32 T 23-04-2016 IPR029016 GAF domain-like DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 PANTHER PTHR11347:SF114 24 367 3.6E-34 T 23-04-2016 IPR027035 Hypoxia/Redox sensor histidine kinase response regulator DosT/DevS GO:0004673|GO:0046777|GO:0070483 DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 PANTHER PTHR11347:SF114 409 508 3.6E-34 T 23-04-2016 IPR027035 Hypoxia/Redox sensor histidine kinase response regulator DosT/DevS GO:0004673|GO:0046777|GO:0070483 DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 Gene3D G3DSA:3.30.450.40 41 197 1.8E-26 T 23-04-2016 IPR029016 GAF domain-like DC74_RS01190 7aca47a21d5c37983b45922c33f22fd9 570 Gene3D G3DSA:3.30.450.40 223 357 2.1E-20 T 23-04-2016 IPR029016 GAF domain-like DC74_RS23355 d864a812a9a143ca511f411058e8453b 376 PANTHER PTHR24220 5 302 1.6E-166 T 23-04-2016 DC74_RS23355 d864a812a9a143ca511f411058e8453b 376 Pfam PF00005 ABC transporter 22 163 4.6E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS23355 d864a812a9a143ca511f411058e8453b 376 PANTHER PTHR24220:SF151 5 302 1.6E-166 T 23-04-2016 DC74_RS23355 d864a812a9a143ca511f411058e8453b 376 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS23355 d864a812a9a143ca511f411058e8453b 376 Gene3D G3DSA:2.40.50.140 283 358 3.8E-9 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS23355 d864a812a9a143ca511f411058e8453b 376 SMART SM00382 30 213 4.1E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS23355 d864a812a9a143ca511f411058e8453b 376 Gene3D G3DSA:3.40.50.300 12 236 4.0E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23355 d864a812a9a143ca511f411058e8453b 376 SUPERFAMILY SSF50331 238 374 1.13E-21 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal DC74_RS23355 d864a812a9a143ca511f411058e8453b 376 Gene3D G3DSA:2.40.50.100 241 282 1.8E-7 T 23-04-2016 DC74_RS23355 d864a812a9a143ca511f411058e8453b 376 Gene3D G3DSA:2.40.50.100 360 374 1.8E-7 T 23-04-2016 DC74_RS23355 d864a812a9a143ca511f411058e8453b 376 SUPERFAMILY SSF52540 6 245 2.42E-83 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23355 d864a812a9a143ca511f411058e8453b 376 Pfam PF03459 TOBE domain 304 365 3.4E-7 T 23-04-2016 IPR005116 Transport-associated OB, type 1 DC74_RS23535 010311445886589fcbda36d33ec2b7c8 92 PANTHER PTHR38031:SF1 1 91 1.4E-25 T 23-04-2016 DC74_RS23535 010311445886589fcbda36d33ec2b7c8 92 Pfam PF02597 ThiS family 5 91 5.3E-18 T 23-04-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 DC74_RS23535 010311445886589fcbda36d33ec2b7c8 92 Gene3D G3DSA:3.10.20.30 3 89 2.8E-31 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS23535 010311445886589fcbda36d33ec2b7c8 92 SUPERFAMILY SSF54285 1 91 2.45E-24 T 23-04-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp DC74_RS23535 010311445886589fcbda36d33ec2b7c8 92 PANTHER PTHR38031 1 91 1.4E-25 T 23-04-2016 DC74_RS06780 3de74a16e5a7faf0b707b3678008cd9b 462 PANTHER PTHR11926:SF16 3 88 1.1E-39 T 23-04-2016 DC74_RS06780 3de74a16e5a7faf0b707b3678008cd9b 462 PANTHER PTHR11926:SF16 104 440 1.1E-39 T 23-04-2016 DC74_RS06780 3de74a16e5a7faf0b707b3678008cd9b 462 Gene3D G3DSA:3.40.50.2000 282 435 1.7E-17 T 23-04-2016 DC74_RS06780 3de74a16e5a7faf0b707b3678008cd9b 462 Gene3D G3DSA:3.40.50.2000 194 281 4.0E-11 T 23-04-2016 DC74_RS06780 3de74a16e5a7faf0b707b3678008cd9b 462 Gene3D G3DSA:3.40.50.2000 8 162 4.0E-11 T 23-04-2016 DC74_RS06780 3de74a16e5a7faf0b707b3678008cd9b 462 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 88 438 1.2E-28 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS06780 3de74a16e5a7faf0b707b3678008cd9b 462 SUPERFAMILY SSF53756 8 451 3.93E-69 T 23-04-2016 DC74_RS06780 3de74a16e5a7faf0b707b3678008cd9b 462 PANTHER PTHR11926 3 88 1.1E-39 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS06780 3de74a16e5a7faf0b707b3678008cd9b 462 PANTHER PTHR11926 104 440 1.1E-39 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS04945 26958e863f7709ce099c6770d3094f4b 245 PANTHER PTHR37314 26 242 3.5E-29 T 23-04-2016 DC74_RS04945 26958e863f7709ce099c6770d3094f4b 245 Pfam PF06912 Protein of unknown function (DUF1275) 26 224 1.5E-34 T 23-04-2016 IPR010699 Protein of unknown function DUF1275 DC74_RS04945 26958e863f7709ce099c6770d3094f4b 245 PANTHER PTHR37314:SF1 26 242 3.5E-29 T 23-04-2016 DC74_RS35940 e7ba95722749ef6b8f2ac2984b57784e 77 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 11 60 3.1E-9 T 23-04-2016 IPR032716 Acyl-CoA carboxylase epsilon subunit DC74_RS13650 16dc107815ac7d30fa3a6e02f8db12d4 217 Gene3D G3DSA:1.10.357.10 16 201 2.7E-30 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS13650 16dc107815ac7d30fa3a6e02f8db12d4 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 9.7E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13650 16dc107815ac7d30fa3a6e02f8db12d4 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 9.7E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13650 16dc107815ac7d30fa3a6e02f8db12d4 217 PANTHER PTHR30055:SF14 12 203 9.3E-73 T 23-04-2016 DC74_RS13650 16dc107815ac7d30fa3a6e02f8db12d4 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 74 1.3E-14 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13650 16dc107815ac7d30fa3a6e02f8db12d4 217 PANTHER PTHR30055 12 203 9.3E-73 T 23-04-2016 DC74_RS13650 16dc107815ac7d30fa3a6e02f8db12d4 217 SUPERFAMILY SSF46689 20 91 3.89E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS16390 86c487867cb0764e3d64a1a4d707a221 482 PIRSF PIRSF006060 10 481 1.1E-67 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS16390 86c487867cb0764e3d64a1a4d707a221 482 Pfam PF00324 Amino acid permease 33 471 8.5E-113 T 23-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 DC74_RS16390 86c487867cb0764e3d64a1a4d707a221 482 ProSitePatterns PS00218 Amino acid permeases signature. 57 87 - T 23-04-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 DC74_RS16390 86c487867cb0764e3d64a1a4d707a221 482 PANTHER PTHR11785 21 467 6.0E-210 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS16390 86c487867cb0764e3d64a1a4d707a221 482 PANTHER PTHR11785:SF29 21 467 6.0E-210 T 23-04-2016 DC74_RS35320 aaa54d7390716613f90476910e37e635 339 SUPERFAMILY SSF54631 205 333 1.3E-24 T 23-04-2016 DC74_RS35320 aaa54d7390716613f90476910e37e635 339 Pfam PF01595 Domain of unknown function DUF21 10 199 3.7E-41 T 23-04-2016 IPR002550 Domain of unknown function DUF21 DC74_RS35320 aaa54d7390716613f90476910e37e635 339 PANTHER PTHR22777 4 333 6.7E-143 T 23-04-2016 DC74_RS35320 aaa54d7390716613f90476910e37e635 339 SMART SM00116 285 333 0.18 T 23-04-2016 IPR000644 CBS domain DC74_RS35320 aaa54d7390716613f90476910e37e635 339 SMART SM00116 225 273 0.017 T 23-04-2016 IPR000644 CBS domain DC74_RS35320 aaa54d7390716613f90476910e37e635 339 Gene3D G3DSA:3.10.580.10 224 332 1.8E-18 T 23-04-2016 DC74_RS35320 aaa54d7390716613f90476910e37e635 339 PANTHER PTHR22777:SF7 4 333 6.7E-143 T 23-04-2016 DC74_RS35320 aaa54d7390716613f90476910e37e635 339 Pfam PF00571 CBS domain 218 270 1.7E-4 T 23-04-2016 IPR000644 CBS domain DC74_RS35320 aaa54d7390716613f90476910e37e635 339 Pfam PF00571 CBS domain 284 333 4.6E-7 T 23-04-2016 IPR000644 CBS domain DC74_RS16200 aeb54c221f653723db0999be94138c98 373 Gene3D G3DSA:3.30.9.10 212 283 7.4E-6 T 23-04-2016 DC74_RS16200 aeb54c221f653723db0999be94138c98 373 Gene3D G3DSA:3.30.9.10 82 134 7.4E-6 T 23-04-2016 DC74_RS16200 aeb54c221f653723db0999be94138c98 373 PANTHER PTHR13847 1 237 6.0E-27 T 23-04-2016 DC74_RS16200 aeb54c221f653723db0999be94138c98 373 PANTHER PTHR13847 275 368 6.0E-27 T 23-04-2016 DC74_RS16200 aeb54c221f653723db0999be94138c98 373 Pfam PF01266 FAD dependent oxidoreductase 3 369 3.7E-45 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DC74_RS16200 aeb54c221f653723db0999be94138c98 373 Gene3D G3DSA:3.50.50.60 135 211 1.6E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS16200 aeb54c221f653723db0999be94138c98 373 Gene3D G3DSA:3.50.50.60 1 79 1.6E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS16200 aeb54c221f653723db0999be94138c98 373 Gene3D G3DSA:3.50.50.60 331 369 1.6E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS16200 aeb54c221f653723db0999be94138c98 373 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 2 365 1.9E-99 T 23-04-2016 IPR017741 FAD-dependent oxidoreductase, HpnW DC74_RS16200 aeb54c221f653723db0999be94138c98 373 SUPERFAMILY SSF51905 331 371 3.24E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS16200 aeb54c221f653723db0999be94138c98 373 SUPERFAMILY SSF51905 1 212 3.24E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS27665 16556b5cd6ce5547bf6d15341d6bedd7 391 PANTHER PTHR19328 66 386 3.6E-54 T 23-04-2016 DC74_RS27665 16556b5cd6ce5547bf6d15341d6bedd7 391 Pfam PF07995 Glucose / Sorbosone dehydrogenase 71 375 8.1E-76 T 23-04-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 DC74_RS27665 16556b5cd6ce5547bf6d15341d6bedd7 391 SUPERFAMILY SSF50952 45 377 3.66E-47 T 23-04-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 DC74_RS27665 16556b5cd6ce5547bf6d15341d6bedd7 391 Gene3D G3DSA:2.120.10.30 55 389 2.7E-89 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS27665 16556b5cd6ce5547bf6d15341d6bedd7 391 Gene3D G3DSA:2.120.10.30 17 22 2.7E-89 T 23-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like DC74_RS20845 fb49f8195fec204d0e4e8ba97f9f64d7 445 PANTHER PTHR11206:SF94 16 438 2.1E-124 T 23-04-2016 DC74_RS20845 fb49f8195fec204d0e4e8ba97f9f64d7 445 PIRSF PIRSF006603 15 445 2.1E-62 T 23-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 DC74_RS20845 fb49f8195fec204d0e4e8ba97f9f64d7 445 PANTHER PTHR11206 16 438 2.1E-124 T 23-04-2016 DC74_RS20845 fb49f8195fec204d0e4e8ba97f9f64d7 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 415 1.6E-99 T 23-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 DC74_RS20845 fb49f8195fec204d0e4e8ba97f9f64d7 445 Pfam PF01554 MatE 25 183 5.5E-28 T 23-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 DC74_RS20845 fb49f8195fec204d0e4e8ba97f9f64d7 445 Pfam PF01554 MatE 243 396 3.1E-21 T 23-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 DC74_RS39790 8eac9277de9fc07bd8c6d7f123ee1527 434 Gene3D G3DSA:1.20.1250.20 1 179 1.6E-29 T 23-04-2016 DC74_RS39790 8eac9277de9fc07bd8c6d7f123ee1527 434 Gene3D G3DSA:1.20.1250.20 247 428 2.0E-15 T 23-04-2016 DC74_RS39790 8eac9277de9fc07bd8c6d7f123ee1527 434 PANTHER PTHR23501:SF7 1 402 5.1E-114 T 23-04-2016 DC74_RS39790 8eac9277de9fc07bd8c6d7f123ee1527 434 SUPERFAMILY SSF103473 233 431 1.05E-58 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS39790 8eac9277de9fc07bd8c6d7f123ee1527 434 SUPERFAMILY SSF103473 2 187 1.05E-58 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS39790 8eac9277de9fc07bd8c6d7f123ee1527 434 PANTHER PTHR23501 1 402 5.1E-114 T 23-04-2016 DC74_RS39790 8eac9277de9fc07bd8c6d7f123ee1527 434 Pfam PF07690 Major Facilitator Superfamily 1 393 4.0E-47 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS08445 31123c779b5b524160056713491c9d2e 523 SUPERFAMILY SSF51905 1 319 8.7E-36 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08445 31123c779b5b524160056713491c9d2e 523 Pfam PF01593 Flavin containing amine oxidoreductase 18 301 3.6E-12 T 23-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 DC74_RS08445 31123c779b5b524160056713491c9d2e 523 PANTHER PTHR10668 3 522 2.1E-128 T 23-04-2016 DC74_RS08445 31123c779b5b524160056713491c9d2e 523 Gene3D G3DSA:3.50.50.60 4 74 1.8E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08445 31123c779b5b524160056713491c9d2e 523 Gene3D G3DSA:3.50.50.60 208 303 1.8E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS08445 31123c779b5b524160056713491c9d2e 523 PANTHER PTHR10668:SF83 3 522 2.1E-128 T 23-04-2016 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 SUPERFAMILY SSF54373 218 323 9.81E-22 T 23-04-2016 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 Hamap MF_00516 Monomeric sarcosine oxidase [soxA]. 1 391 63.58 T 23-04-2016 IPR006281 Sarcosine oxidase, monomeric GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 PANTHER PTHR10961 1 373 5.2E-108 T 23-04-2016 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 Pfam PF01266 FAD dependent oxidoreductase 6 363 1.8E-46 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 9 22 - T 23-04-2016 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 PANTHER PTHR10961:SF7 1 373 5.2E-108 T 23-04-2016 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 Gene3D G3DSA:3.30.9.10 217 323 1.3E-43 T 23-04-2016 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 Gene3D G3DSA:3.30.9.10 62 147 1.3E-43 T 23-04-2016 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 SUPERFAMILY SSF51905 323 381 3.02E-41 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 SUPERFAMILY SSF51905 4 220 3.02E-41 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 Gene3D G3DSA:3.50.50.60 326 382 6.7E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 Gene3D G3DSA:3.50.50.60 4 59 6.7E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS06685 f57e4b9cd9e8182c5b8b2a1940dbf22a 395 Gene3D G3DSA:3.50.50.60 148 212 6.7E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS20030 e668f6df75d0ef3f799b437ed67af8de 356 PANTHER PTHR32308 6 202 3.3E-135 T 23-04-2016 IPR011206 Citrate lyase beta subunit-like DC74_RS20030 e668f6df75d0ef3f799b437ed67af8de 356 Gene3D G3DSA:3.20.20.60 23 288 3.3E-65 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS20030 e668f6df75d0ef3f799b437ed67af8de 356 PANTHER PTHR32308:SF2 227 347 3.3E-135 T 23-04-2016 DC74_RS20030 e668f6df75d0ef3f799b437ed67af8de 356 PIRSF PIRSF015582 14 347 3.9E-83 T 23-04-2016 IPR011206 Citrate lyase beta subunit-like DC74_RS20030 e668f6df75d0ef3f799b437ed67af8de 356 SUPERFAMILY SSF51621 220 288 8.79E-53 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS20030 e668f6df75d0ef3f799b437ed67af8de 356 SUPERFAMILY SSF51621 24 193 8.79E-53 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS20030 e668f6df75d0ef3f799b437ed67af8de 356 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 32 276 1.1E-28 T 23-04-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 DC74_RS20030 e668f6df75d0ef3f799b437ed67af8de 356 PANTHER PTHR32308:SF2 6 202 3.3E-135 T 23-04-2016 DC74_RS20030 e668f6df75d0ef3f799b437ed67af8de 356 PANTHER PTHR32308 227 347 3.3E-135 T 23-04-2016 IPR011206 Citrate lyase beta subunit-like DC74_RS23225 632bebf01c16b4e407956c6062febcd9 469 Pfam PF11209 Protein of unknown function (DUF2993) 150 325 2.6E-29 T 23-04-2016 IPR021373 Protein of unknown function DUF2993 DC74_RS39710 d51bc148832daabbfb5ac5070b1e70ad 325 Gene3D G3DSA:1.10.10.60 213 269 2.0E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39710 d51bc148832daabbfb5ac5070b1e70ad 325 SUPERFAMILY SSF46689 270 320 3.85E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39710 d51bc148832daabbfb5ac5070b1e70ad 325 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 270 315 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS39710 d51bc148832daabbfb5ac5070b1e70ad 325 Pfam PF14525 AraC-binding-like domain 21 198 6.1E-19 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS39710 d51bc148832daabbfb5ac5070b1e70ad 325 Pfam PF12833 Helix-turn-helix domain 240 319 2.3E-21 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS39710 d51bc148832daabbfb5ac5070b1e70ad 325 PANTHER PTHR11019 66 319 1.3E-27 T 23-04-2016 DC74_RS39710 d51bc148832daabbfb5ac5070b1e70ad 325 PANTHER PTHR11019:SF50 66 319 1.3E-27 T 23-04-2016 DC74_RS39710 d51bc148832daabbfb5ac5070b1e70ad 325 SMART SM00342 234 319 4.6E-23 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS39710 d51bc148832daabbfb5ac5070b1e70ad 325 Gene3D G3DSA:1.10.10.60 270 319 1.9E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS20240 89fc96d7e3f4cdaad22d621d051ff016 597 Pfam PF10138 vWA found in TerF C terminus 392 593 6.6E-63 T 23-04-2016 IPR019303 vWA found in TerF C terminus DC74_RS20240 89fc96d7e3f4cdaad22d621d051ff016 597 SMART SM00327 392 566 1.7E-8 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS20240 89fc96d7e3f4cdaad22d621d051ff016 597 Gene3D G3DSA:3.40.50.410 391 531 6.4E-7 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS20240 89fc96d7e3f4cdaad22d621d051ff016 597 SUPERFAMILY SSF53300 393 547 4.01E-16 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS38630 f0a8aad9fdf4d9ca0ed13c2f940072c3 344 PIRSF PIRSF029792 12 344 2.8E-129 T 23-04-2016 IPR008794 Proline racemase family DC74_RS38630 f0a8aad9fdf4d9ca0ed13c2f940072c3 344 SUPERFAMILY SSF54506 15 342 3.14E-117 T 23-04-2016 DC74_RS38630 f0a8aad9fdf4d9ca0ed13c2f940072c3 344 PANTHER PTHR33442 5 344 1.2E-164 T 23-04-2016 DC74_RS38630 f0a8aad9fdf4d9ca0ed13c2f940072c3 344 Pfam PF05544 Proline racemase 21 343 6.3E-130 T 23-04-2016 IPR008794 Proline racemase family DC74_RS38630 f0a8aad9fdf4d9ca0ed13c2f940072c3 344 Gene3D G3DSA:3.10.310.10 167 332 1.5E-63 T 23-04-2016 DC74_RS38630 f0a8aad9fdf4d9ca0ed13c2f940072c3 344 PANTHER PTHR33442:SF2 5 344 1.2E-164 T 23-04-2016 DC74_RS38630 f0a8aad9fdf4d9ca0ed13c2f940072c3 344 Gene3D G3DSA:3.10.310.10 15 166 3.1E-67 T 23-04-2016 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 PANTHER PTHR11712 10 409 2.4E-84 T 23-04-2016 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 Pfam PF00067 Cytochrome P450 280 380 7.5E-14 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 Pfam PF00067 Cytochrome P450 199 271 2.1E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 352 361 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 PRINTS PR00359 B-class P450 signature 279 290 6.4E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 PRINTS PR00359 B-class P450 signature 101 112 6.4E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 PRINTS PR00359 B-class P450 signature 162 177 6.4E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 PRINTS PR00359 B-class P450 signature 325 340 6.4E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 PRINTS PR00359 B-class P450 signature 197 219 6.4E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 PRINTS PR00359 B-class P450 signature 350 359 6.4E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 PRINTS PR00359 B-class P450 signature 297 324 6.4E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 PRINTS PR00359 B-class P450 signature 359 370 6.4E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 PRINTS PR00359 B-class P450 signature 145 161 6.4E-51 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 SUPERFAMILY SSF48264 11 408 2.23E-87 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS05655 b5c5c21dd47734d166bbd3cd742fb3fa 409 Gene3D G3DSA:1.10.630.10 11 408 1.7E-114 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS08025 4f4060dd2d2848fea3e3400633fd860d 177 SUPERFAMILY SSF81923 110 173 2.75E-5 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS08025 4f4060dd2d2848fea3e3400633fd860d 177 Gene3D G3DSA:1.10.1780.10 22 166 1.2E-14 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS08025 4f4060dd2d2848fea3e3400633fd860d 177 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 138 168 0.0039 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS08025 4f4060dd2d2848fea3e3400633fd860d 177 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 34 56 0.05 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 DC74_RS34575 98b58955f7d110abed1363f820e0f246 544 SUPERFAMILY SSF52540 14 236 7.95E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34575 98b58955f7d110abed1363f820e0f246 544 PANTHER PTHR19211 14 277 1.5E-113 T 23-04-2016 DC74_RS34575 98b58955f7d110abed1363f820e0f246 544 PANTHER PTHR19211 313 524 1.5E-113 T 23-04-2016 DC74_RS34575 98b58955f7d110abed1363f820e0f246 544 ProSitePatterns PS00211 ABC transporters family signature. 466 480 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS34575 98b58955f7d110abed1363f820e0f246 544 Pfam PF00005 ABC transporter 371 494 6.2E-19 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS34575 98b58955f7d110abed1363f820e0f246 544 Pfam PF00005 ABC transporter 21 193 1.6E-22 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS34575 98b58955f7d110abed1363f820e0f246 544 SUPERFAMILY SSF52540 359 525 5.85E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34575 98b58955f7d110abed1363f820e0f246 544 Gene3D G3DSA:3.40.50.300 141 278 1.4E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34575 98b58955f7d110abed1363f820e0f246 544 Gene3D G3DSA:3.40.50.300 371 522 1.9E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34575 98b58955f7d110abed1363f820e0f246 544 Gene3D G3DSA:3.40.50.300 15 102 1.4E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34575 98b58955f7d110abed1363f820e0f246 544 SMART SM00382 375 539 6.2E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS34575 98b58955f7d110abed1363f820e0f246 544 SMART SM00382 30 237 4.9E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS19125 18910935c593940192a58bf2aa899d1f 279 Gene3D G3DSA:3.40.190.10 73 174 2.7E-36 T 23-04-2016 DC74_RS19125 18910935c593940192a58bf2aa899d1f 279 PANTHER PTHR37690 1 273 1.9E-68 T 23-04-2016 DC74_RS19125 18910935c593940192a58bf2aa899d1f 279 Pfam PF02621 Menaquinone biosynthesis 1 256 1.8E-68 T 23-04-2016 IPR003773 Menaquinone biosynthesis enzyme UniPathway: UPA00079 DC74_RS19125 18910935c593940192a58bf2aa899d1f 279 Hamap MF_00995 Chorismate dehydratase [mqnA]. 1 262 28.864 T 23-04-2016 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374|UniPathway: UPA00079 DC74_RS19125 18910935c593940192a58bf2aa899d1f 279 SUPERFAMILY SSF53850 1 255 1.81E-74 T 23-04-2016 DC74_RS19125 18910935c593940192a58bf2aa899d1f 279 Gene3D G3DSA:3.40.190.10 175 272 4.7E-65 T 23-04-2016 DC74_RS19125 18910935c593940192a58bf2aa899d1f 279 Gene3D G3DSA:3.40.190.10 1 72 4.7E-65 T 23-04-2016 DC74_RS18735 43bbe46b7f9c3d95a04785d78249ab73 214 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 7 208 6.3E-92 T 23-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18735 43bbe46b7f9c3d95a04785d78249ab73 214 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 5 211 40.725 T 23-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18735 43bbe46b7f9c3d95a04785d78249ab73 214 SUPERFAMILY SSF50447 5 212 5.47E-82 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain DC74_RS18735 43bbe46b7f9c3d95a04785d78249ab73 214 PANTHER PTHR11229 7 212 5.8E-111 T 23-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18735 43bbe46b7f9c3d95a04785d78249ab73 214 ProSitePatterns PS00474 Ribosomal protein L3 signature. 105 128 - T 23-04-2016 IPR019926 Ribosomal protein L3, conserved site DC74_RS18735 43bbe46b7f9c3d95a04785d78249ab73 214 Gene3D G3DSA:2.40.30.10 162 211 2.6E-12 T 23-04-2016 DC74_RS18735 43bbe46b7f9c3d95a04785d78249ab73 214 Gene3D G3DSA:2.40.30.10 7 36 2.6E-12 T 23-04-2016 DC74_RS18735 43bbe46b7f9c3d95a04785d78249ab73 214 Pfam PF00297 Ribosomal protein L3 98 186 6.3E-16 T 23-04-2016 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18735 43bbe46b7f9c3d95a04785d78249ab73 214 Gene3D G3DSA:4.10.960.10 80 161 7.6E-34 T 23-04-2016 DC74_RS09100 bdb0d1d16c212d87c2c261083e393025 261 PANTHER PTHR11820 55 259 1.6E-83 T 23-04-2016 DC74_RS09100 bdb0d1d16c212d87c2c261083e393025 261 PANTHER PTHR11820:SF6 55 259 1.6E-83 T 23-04-2016 DC74_RS09100 bdb0d1d16c212d87c2c261083e393025 261 Gene3D G3DSA:3.90.850.10 58 258 1.5E-73 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS09100 bdb0d1d16c212d87c2c261083e393025 261 SUPERFAMILY SSF56529 66 257 8.24E-66 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS09100 bdb0d1d16c212d87c2c261083e393025 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 80 257 2.9E-57 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS27775 cb9fea99bca1dd57e74ee6ac48f924da 438 SUPERFAMILY SSF103473 1 420 7.46E-63 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS27775 cb9fea99bca1dd57e74ee6ac48f924da 438 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS27775 cb9fea99bca1dd57e74ee6ac48f924da 438 ProSitePatterns PS00216 Sugar transport proteins signature 1. 288 305 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS27775 cb9fea99bca1dd57e74ee6ac48f924da 438 PANTHER PTHR23508 3 436 4.0E-193 T 23-04-2016 DC74_RS27775 cb9fea99bca1dd57e74ee6ac48f924da 438 Gene3D G3DSA:1.20.1250.20 7 206 6.0E-22 T 23-04-2016 DC74_RS27775 cb9fea99bca1dd57e74ee6ac48f924da 438 Gene3D G3DSA:1.20.1250.20 231 416 1.1E-22 T 23-04-2016 DC74_RS27775 cb9fea99bca1dd57e74ee6ac48f924da 438 Pfam PF07690 Major Facilitator Superfamily 43 350 2.7E-24 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS27775 cb9fea99bca1dd57e74ee6ac48f924da 438 PANTHER PTHR23508:SF4 3 436 4.0E-193 T 23-04-2016 DC74_RS31330 1b02d0bcd80f85924efc3444af5660ea 92 SUPERFAMILY SSF89957 2 75 1.31E-7 T 23-04-2016 IPR029756 MTH1187/YkoF-like DC74_RS31330 1b02d0bcd80f85924efc3444af5660ea 92 Gene3D G3DSA:3.30.70.930 20 76 3.8E-6 T 23-04-2016 IPR029756 MTH1187/YkoF-like DC74_RS32840 7c96d258ff91db18374bb29d512422b0 302 PANTHER PTHR10245:SF20 1 302 1.6E-95 T 23-04-2016 DC74_RS32840 7c96d258ff91db18374bb29d512422b0 302 SUPERFAMILY SSF47413 26 83 1.72E-6 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS32840 7c96d258ff91db18374bb29d512422b0 302 Gene3D G3DSA:1.10.260.40 29 83 1.5E-6 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS32840 7c96d258ff91db18374bb29d512422b0 302 PANTHER PTHR10245 1 302 1.6E-95 T 23-04-2016 DC74_RS32840 7c96d258ff91db18374bb29d512422b0 302 Pfam PF13560 Helix-turn-helix domain 30 89 1.4E-13 T 23-04-2016 DC74_RS32840 7c96d258ff91db18374bb29d512422b0 302 SMART SM00530 33 88 9.5E-4 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS15025 a6fbecce4692561f1bf85ff4163cf074 366 Pfam PF03060 Nitronate monooxygenase 4 344 6.2E-108 T 23-04-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 DC74_RS15025 a6fbecce4692561f1bf85ff4163cf074 366 PANTHER PTHR32332:SF12 1 79 3.9E-114 T 23-04-2016 DC74_RS15025 a6fbecce4692561f1bf85ff4163cf074 366 PANTHER PTHR32332:SF12 106 348 3.9E-114 T 23-04-2016 DC74_RS15025 a6fbecce4692561f1bf85ff4163cf074 366 Gene3D G3DSA:3.20.20.70 4 334 1.6E-67 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS15025 a6fbecce4692561f1bf85ff4163cf074 366 SUPERFAMILY SSF51412 99 348 5.04E-61 T 23-04-2016 DC74_RS15025 a6fbecce4692561f1bf85ff4163cf074 366 SUPERFAMILY SSF51412 9 72 5.04E-61 T 23-04-2016 DC74_RS15025 a6fbecce4692561f1bf85ff4163cf074 366 PANTHER PTHR32332 1 79 3.9E-114 T 23-04-2016 DC74_RS15025 a6fbecce4692561f1bf85ff4163cf074 366 PANTHER PTHR32332 106 348 3.9E-114 T 23-04-2016 DC74_RS10235 0b151d82dc48f2951b306f9ec4de94e2 150 Pfam PF14108 Domain of unknown function (DUF4281) 6 130 9.2E-32 T 23-04-2016 IPR025461 ABA DEFICIENT 4-like DC74_RS37110 225797af39d3ceac1045db285956d262 221 Pfam PF16859 Bacterial transcriptional repressor C-terminal 94 202 1.8E-24 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS37110 225797af39d3ceac1045db285956d262 221 SUPERFAMILY SSF46689 28 87 1.39E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS37110 225797af39d3ceac1045db285956d262 221 PANTHER PTHR30328 9 214 6.8E-51 T 23-04-2016 DC74_RS37110 225797af39d3ceac1045db285956d262 221 Gene3D G3DSA:1.10.10.60 27 75 4.0E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS37110 225797af39d3ceac1045db285956d262 221 SUPERFAMILY SSF48498 95 209 1.13E-18 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS37110 225797af39d3ceac1045db285956d262 221 Gene3D G3DSA:1.10.357.10 77 212 1.2E-38 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS37110 225797af39d3ceac1045db285956d262 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 79 5.7E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS37110 225797af39d3ceac1045db285956d262 221 PANTHER PTHR30328:SF2 9 214 6.8E-51 T 23-04-2016 DC74_RS37670 1825e008a48fd2a20f9651ba6b2bb9f4 174 Pfam PF14016 Protein of unknown function (DUF4232) 46 144 1.1E-6 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS23485 680fb4a9421e4f1eabbca4b6a79bef06 414 Gene3D G3DSA:2.30.40.10 364 394 1.2E-9 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS23485 680fb4a9421e4f1eabbca4b6a79bef06 414 PANTHER PTHR11113:SF7 1 411 5.0E-135 T 23-04-2016 DC74_RS23485 680fb4a9421e4f1eabbca4b6a79bef06 414 PIRSF PIRSF038994 23 411 1.2E-107 T 23-04-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395 DC74_RS23485 680fb4a9421e4f1eabbca4b6a79bef06 414 PANTHER PTHR11113 1 411 5.0E-135 T 23-04-2016 DC74_RS23485 680fb4a9421e4f1eabbca4b6a79bef06 414 Pfam PF01979 Amidohydrolase family 79 394 6.6E-27 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS23485 680fb4a9421e4f1eabbca4b6a79bef06 414 SUPERFAMILY SSF51338 7 82 4.13E-13 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS23485 680fb4a9421e4f1eabbca4b6a79bef06 414 SUPERFAMILY SSF51338 379 395 4.13E-13 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS23485 680fb4a9421e4f1eabbca4b6a79bef06 414 SUPERFAMILY SSF51556 82 379 1.5E-90 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS23485 680fb4a9421e4f1eabbca4b6a79bef06 414 Gene3D G3DSA:2.30.40.10 13 83 2.1E-12 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS23485 680fb4a9421e4f1eabbca4b6a79bef06 414 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 62 402 8.8E-77 T 23-04-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395 DC74_RS23485 680fb4a9421e4f1eabbca4b6a79bef06 414 Gene3D G3DSA:3.20.20.140 84 363 2.5E-97 T 23-04-2016 DC74_RS18610 401b86736addbdbf9744abdb2b4aff0e 134 SUPERFAMILY SSF53137 19 134 4.8E-50 T 23-04-2016 DC74_RS18610 401b86736addbdbf9744abdb2b4aff0e 134 Pfam PF00411 Ribosomal protein S11 24 133 1.3E-48 T 23-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 DC74_RS18610 401b86736addbdbf9744abdb2b4aff0e 134 Gene3D G3DSA:3.30.420.80 11 134 2.3E-58 T 23-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 DC74_RS18610 401b86736addbdbf9744abdb2b4aff0e 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 11 134 34.325 T 23-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 DC74_RS18610 401b86736addbdbf9744abdb2b4aff0e 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 23-04-2016 IPR018102 Ribosomal S11, conserved site DC74_RS18610 401b86736addbdbf9744abdb2b4aff0e 134 PANTHER PTHR11759 15 134 1.1E-69 T 23-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 DC74_RS18610 401b86736addbdbf9744abdb2b4aff0e 134 PIRSF PIRSF002131 4 134 4.3E-54 T 23-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 DC74_RS18610 401b86736addbdbf9744abdb2b4aff0e 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 1.7E-59 T 23-04-2016 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS01960 319af0e1bf52703f1deda76b7fd6f326 123 SUPERFAMILY SSF54909 1 118 2.09E-31 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS01960 319af0e1bf52703f1deda76b7fd6f326 123 PANTHER PTHR35174 2 117 2.5E-29 T 23-04-2016 DC74_RS01960 319af0e1bf52703f1deda76b7fd6f326 123 Gene3D G3DSA:3.30.70.1060 1 117 2.1E-37 T 23-04-2016 DC74_RS01960 319af0e1bf52703f1deda76b7fd6f326 123 Pfam PF03795 YCII-related domain 1 115 4.4E-19 T 23-04-2016 IPR005545 YCII-related DC74_RS10455 d2a17520e5987771dc0f6c23cb308c31 409 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 409 53.417 T 23-04-2016 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 DC74_RS10455 d2a17520e5987771dc0f6c23cb308c31 409 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 39 333 3.6E-80 T 23-04-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 DC74_RS10455 d2a17520e5987771dc0f6c23cb308c31 409 SUPERFAMILY SSF52374 32 333 2.09E-65 T 23-04-2016 DC74_RS10455 d2a17520e5987771dc0f6c23cb308c31 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 241 262 2.1E-18 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DC74_RS10455 d2a17520e5987771dc0f6c23cb308c31 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 2.1E-18 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DC74_RS10455 d2a17520e5987771dc0f6c23cb308c31 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 2.1E-18 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DC74_RS10455 d2a17520e5987771dc0f6c23cb308c31 409 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 210 228 2.1E-18 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DC74_RS10455 d2a17520e5987771dc0f6c23cb308c31 409 Gene3D G3DSA:3.40.50.620 37 326 2.9E-74 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS10455 d2a17520e5987771dc0f6c23cb308c31 409 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 409 1.2E-202 T 23-04-2016 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 DC74_RS10455 d2a17520e5987771dc0f6c23cb308c31 409 PANTHER PTHR10890 1 381 9.1E-248 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DC74_RS10455 d2a17520e5987771dc0f6c23cb308c31 409 PANTHER PTHR10890:SF5 1 381 9.1E-248 T 23-04-2016 DC74_RS35045 fd9d5574b69d8aefb82d07d508412078 234 PANTHER PTHR34071 11 208 3.4E-45 T 23-04-2016 DC74_RS35045 fd9d5574b69d8aefb82d07d508412078 234 PANTHER PTHR34071:SF2 11 208 3.4E-45 T 23-04-2016 DC74_RS35045 fd9d5574b69d8aefb82d07d508412078 234 Gene3D G3DSA:2.30.110.10 6 199 1.2E-59 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS35045 fd9d5574b69d8aefb82d07d508412078 234 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 35 176 3.8E-41 T 23-04-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related DC74_RS35045 fd9d5574b69d8aefb82d07d508412078 234 SUPERFAMILY SSF50475 16 199 3.31E-47 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS05750 f77de24d6f20c5540a300ee49862c427 442 PANTHER PTHR21021 203 441 1.8E-28 T 23-04-2016 DC74_RS05750 f77de24d6f20c5540a300ee49862c427 442 SMART SM00331 219 432 6.4E-20 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS05750 f77de24d6f20c5540a300ee49862c427 442 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 248 432 1.1E-29 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS24820 1e4410da4fbc5e030af40b3146defd30 109 SUPERFAMILY SSF47090 17 86 9.26E-17 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS24820 1e4410da4fbc5e030af40b3146defd30 109 Gene3D G3DSA:1.10.101.10 21 87 1.5E-17 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS24820 1e4410da4fbc5e030af40b3146defd30 109 Pfam PF01471 Putative peptidoglycan binding domain 30 76 5.5E-13 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS29760 df0cb8adb337ee541dbe6bb9ddab31a7 132 Gene3D G3DSA:3.40.50.1010 62 117 2.6E-5 T 23-04-2016 IPR029060 PIN domain-like DC74_RS17235 0f10b267d7ae32eefe9812c486efc24a 114 SUPERFAMILY SSF46785 9 95 2.07E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17235 0f10b267d7ae32eefe9812c486efc24a 114 Gene3D G3DSA:1.10.10.10 7 95 3.6E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17235 0f10b267d7ae32eefe9812c486efc24a 114 PANTHER PTHR37318 1 99 1.2E-19 T 23-04-2016 DC74_RS17235 0f10b267d7ae32eefe9812c486efc24a 114 Pfam PF13601 Winged helix DNA-binding domain 16 94 1.1E-25 T 23-04-2016 IPR027395 Winged helix DNA-binding domain DC74_RS04715 20d9ffd769ce8472506d81f647445334 146 Gene3D G3DSA:2.60.120.10 14 134 4.2E-20 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS04715 20d9ffd769ce8472506d81f647445334 146 SUPERFAMILY SSF51182 32 130 2.67E-16 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS04715 20d9ffd769ce8472506d81f647445334 146 Pfam PF07883 Cupin domain 45 101 2.3E-11 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS04715 20d9ffd769ce8472506d81f647445334 146 PANTHER PTHR38599 16 137 1.1E-33 T 23-04-2016 DC74_RS04715 20d9ffd769ce8472506d81f647445334 146 PANTHER PTHR38599:SF1 16 137 1.1E-33 T 23-04-2016 DC74_RS36265 69cdbaafb05d81399dbd81bb13b080e2 447 SUPERFAMILY SSF51338 369 443 1.73E-15 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS36265 69cdbaafb05d81399dbd81bb13b080e2 447 SUPERFAMILY SSF51338 2 55 1.73E-15 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS36265 69cdbaafb05d81399dbd81bb13b080e2 447 PANTHER PTHR11271:SF37 1 445 2.4E-171 T 23-04-2016 DC74_RS36265 69cdbaafb05d81399dbd81bb13b080e2 447 SUPERFAMILY SSF51556 55 369 4.17E-92 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS36265 69cdbaafb05d81399dbd81bb13b080e2 447 Gene3D G3DSA:3.20.20.140 61 385 5.4E-101 T 23-04-2016 DC74_RS36265 69cdbaafb05d81399dbd81bb13b080e2 447 Pfam PF01979 Amidohydrolase family 52 400 1.5E-60 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS36265 69cdbaafb05d81399dbd81bb13b080e2 447 PANTHER PTHR11271 1 445 2.4E-171 T 23-04-2016 DC74_RS36265 69cdbaafb05d81399dbd81bb13b080e2 447 Gene3D G3DSA:2.30.40.10 2 60 3.3E-12 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS01285 9742b77a211fd889c69dd610f6c7192d 88 PANTHER PTHR35344:SF2 8 69 8.9E-21 T 23-04-2016 DC74_RS01285 9742b77a211fd889c69dd610f6c7192d 88 Pfam PF00741 Gas vesicle protein 21 58 9.4E-13 T 23-04-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 DC74_RS01285 9742b77a211fd889c69dd610f6c7192d 88 PANTHER PTHR35344 8 69 8.9E-21 T 23-04-2016 DC74_RS34590 72114792378d37fd1ac27939a8313d4a 381 Gene3D G3DSA:3.40.50.1100 153 327 3.8E-38 T 23-04-2016 DC74_RS34590 72114792378d37fd1ac27939a8313d4a 381 PANTHER PTHR10314:SF8 32 351 1.4E-87 T 23-04-2016 DC74_RS34590 72114792378d37fd1ac27939a8313d4a 381 Gene3D G3DSA:3.40.50.1100 62 152 2.9E-20 T 23-04-2016 DC74_RS34590 72114792378d37fd1ac27939a8313d4a 381 PANTHER PTHR10314 32 351 1.4E-87 T 23-04-2016 DC74_RS34590 72114792378d37fd1ac27939a8313d4a 381 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 32 315 7.5E-50 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS34590 72114792378d37fd1ac27939a8313d4a 381 SUPERFAMILY SSF53686 27 335 1.96E-64 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS31695 16aef64d70120a6688b99124080a9448 268 Gene3D G3DSA:3.30.540.10 4 163 8.0E-39 T 23-04-2016 DC74_RS31695 16aef64d70120a6688b99124080a9448 268 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 87 100 - T 23-04-2016 IPR020583 Inositol monophosphatase, metal-binding site DC74_RS31695 16aef64d70120a6688b99124080a9448 268 Pfam PF00459 Inositol monophosphatase family 5 240 1.7E-55 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS31695 16aef64d70120a6688b99124080a9448 268 PANTHER PTHR20854 12 245 2.3E-56 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS31695 16aef64d70120a6688b99124080a9448 268 SUPERFAMILY SSF56655 8 264 1.96E-61 T 23-04-2016 DC74_RS31695 16aef64d70120a6688b99124080a9448 268 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 23-04-2016 IPR020550 Inositol monophosphatase, conserved site GO:0046854 DC74_RS31695 16aef64d70120a6688b99124080a9448 268 Gene3D G3DSA:3.40.190.80 164 265 3.5E-17 T 23-04-2016 DC74_RS31695 16aef64d70120a6688b99124080a9448 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 1.2E-24 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS31695 16aef64d70120a6688b99124080a9448 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 136 159 1.2E-24 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS31695 16aef64d70120a6688b99124080a9448 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 1.2E-24 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS31695 16aef64d70120a6688b99124080a9448 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 1.2E-24 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS31695 16aef64d70120a6688b99124080a9448 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 1.2E-24 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS31695 16aef64d70120a6688b99124080a9448 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 87 103 1.2E-24 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 DC74_RS28960 fe59b58e62e8363bcc0c7e766f4efb04 301 PANTHER PTHR16222 14 293 1.5E-45 T 23-04-2016 DC74_RS28960 fe59b58e62e8363bcc0c7e766f4efb04 301 Pfam PF03747 ADP-ribosylglycohydrolase 18 278 4.5E-43 T 23-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 DC74_RS28960 fe59b58e62e8363bcc0c7e766f4efb04 301 PANTHER PTHR16222:SF12 14 293 1.5E-45 T 23-04-2016 DC74_RS28960 fe59b58e62e8363bcc0c7e766f4efb04 301 SUPERFAMILY SSF101478 13 294 2.48E-49 T 23-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 DC74_RS18875 d98b5676f60dabce59249c0659735056 162 SUPERFAMILY SSF89963 5 88 1.83E-29 T 23-04-2016 IPR007551 Protein of unknown function DUF520 DC74_RS18875 d98b5676f60dabce59249c0659735056 162 Gene3D G3DSA:3.30.70.860 97 162 1.3E-28 T 23-04-2016 DC74_RS18875 d98b5676f60dabce59249c0659735056 162 Gene3D G3DSA:3.30.70.990 11 96 3.4E-32 T 23-04-2016 DC74_RS18875 d98b5676f60dabce59249c0659735056 162 PANTHER PTHR30476:SF0 2 162 6.0E-85 T 23-04-2016 DC74_RS18875 d98b5676f60dabce59249c0659735056 162 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 162 25.925 T 23-04-2016 IPR007551 Protein of unknown function DUF520 DC74_RS18875 d98b5676f60dabce59249c0659735056 162 Pfam PF04461 Protein of unknown function (DUF520) 4 162 5.3E-61 T 23-04-2016 IPR007551 Protein of unknown function DUF520 DC74_RS18875 d98b5676f60dabce59249c0659735056 162 PANTHER PTHR30476 2 162 6.0E-85 T 23-04-2016 DC74_RS18875 d98b5676f60dabce59249c0659735056 162 SUPERFAMILY SSF89963 90 162 4.18E-23 T 23-04-2016 IPR007551 Protein of unknown function DUF520 DC74_RS33095 dd013ec575e5bba20da51714f68ebdec 480 Gene3D G3DSA:1.10.390.10 313 446 4.4E-25 T 23-04-2016 DC74_RS33095 dd013ec575e5bba20da51714f68ebdec 480 PANTHER PTHR11533 20 446 4.1E-86 T 23-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 DC74_RS33095 dd013ec575e5bba20da51714f68ebdec 480 Pfam PF01433 Peptidase family M1 292 346 2.9E-18 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS33095 dd013ec575e5bba20da51714f68ebdec 480 Pfam PF01433 Peptidase family M1 33 262 2.1E-22 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS33095 dd013ec575e5bba20da51714f68ebdec 480 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 146 161 2.5E-11 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS33095 dd013ec575e5bba20da51714f68ebdec 480 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 299 314 2.5E-11 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS33095 dd013ec575e5bba20da51714f68ebdec 480 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 318 330 2.5E-11 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS33095 dd013ec575e5bba20da51714f68ebdec 480 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 193 208 2.5E-11 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS33095 dd013ec575e5bba20da51714f68ebdec 480 SUPERFAMILY SSF63737 19 209 6.41E-34 T 23-04-2016 DC74_RS33095 dd013ec575e5bba20da51714f68ebdec 480 SUPERFAMILY SSF55486 219 446 2.2E-50 T 23-04-2016 DC74_RS33095 dd013ec575e5bba20da51714f68ebdec 480 PANTHER PTHR11533:SF163 20 446 4.1E-86 T 23-04-2016 DC74_RS11510 5a300999ad12eceb029d0ec066ed8541 329 PANTHER PTHR34308 1 316 1.6E-98 T 23-04-2016 DC74_RS11510 5a300999ad12eceb029d0ec066ed8541 329 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 312 93.858 T 23-04-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 DC74_RS11510 5a300999ad12eceb029d0ec066ed8541 329 PANTHER PTHR34308:SF1 1 316 1.6E-98 T 23-04-2016 DC74_RS11510 5a300999ad12eceb029d0ec066ed8541 329 Pfam PF03186 CobD/Cbib protein 13 290 3.5E-85 T 23-04-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 PANTHER PTHR24286 43 360 3.2E-44 T 23-04-2016 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 Pfam PF00067 Cytochrome P450 124 360 4.8E-46 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 PRINTS PR00385 P450 superfamily signature 192 209 5.0E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 PRINTS PR00385 P450 superfamily signature 245 256 5.0E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 PRINTS PR00385 P450 superfamily signature 320 329 5.0E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 PRINTS PR00385 P450 superfamily signature 329 340 5.0E-7 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 Gene3D G3DSA:1.10.630.10 6 360 1.7E-64 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 PRINTS PR00465 E-class P450 group IV signature 240 256 3.5E-12 T 23-04-2016 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 PRINTS PR00465 E-class P450 group IV signature 183 209 3.5E-12 T 23-04-2016 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 PRINTS PR00465 E-class P450 group IV signature 313 329 3.5E-12 T 23-04-2016 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 PRINTS PR00465 E-class P450 group IV signature 273 287 3.5E-12 T 23-04-2016 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 PRINTS PR00465 E-class P450 group IV signature 289 307 3.5E-12 T 23-04-2016 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03315 c9afa939743c5a9870d699e34887f37d 383 SUPERFAMILY SSF48264 18 361 8.51E-63 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 SMART SM00448 2 115 6.7E-30 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 PANTHER PTHR26402:SF564 2 214 2.0E-98 T 23-04-2016 DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 5.3E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 5.3E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 5.3E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 PANTHER PTHR26402 2 214 2.0E-98 T 23-04-2016 DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 1.1E-17 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 Gene3D G3DSA:1.10.10.10 125 215 2.6E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 Pfam PF00072 Response regulator receiver domain 4 113 4.2E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 SUPERFAMILY SSF46894 139 214 1.9E-22 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 Gene3D G3DSA:3.40.50.2300 1 124 4.2E-39 T 23-04-2016 DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 SUPERFAMILY SSF52172 1 134 2.85E-34 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS19840 796cd516fa4db1c08b0ad3d386f4e402 218 SMART SM00421 151 208 2.1E-26 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS12000 57e2923be3e0ceb8c9cf3abb625c2a07 650 Pfam PF13625 Helicase conserved C-terminal domain 452 572 2.9E-34 T 23-04-2016 IPR032830 Helicase XPB/Ssl2, N-terminal domain DC74_RS04080 e8f75eda47bb20bbf58c646b2393f813 169 Pfam PF04978 Protein of unknown function (DUF664) 8 167 1.4E-21 T 23-04-2016 IPR007061 Protein of unknown function DUF664 DC74_RS04080 e8f75eda47bb20bbf58c646b2393f813 169 SUPERFAMILY SSF109854 5 168 9.16E-32 T 23-04-2016 DC74_RS04080 e8f75eda47bb20bbf58c646b2393f813 169 Gene3D G3DSA:1.20.120.450 3 168 4.5E-69 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS32620 a5c4a4e76cc562b14e692b51e1b8de58 219 SUPERFAMILY SSF56784 2 213 1.29E-25 T 23-04-2016 IPR023214 HAD-like domain DC74_RS32620 a5c4a4e76cc562b14e692b51e1b8de58 219 PANTHER PTHR18901 5 217 8.7E-15 T 23-04-2016 DC74_RS32620 a5c4a4e76cc562b14e692b51e1b8de58 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 181 1.3E-8 T 23-04-2016 IPR023214 HAD-like domain DC74_RS32620 a5c4a4e76cc562b14e692b51e1b8de58 219 Gene3D G3DSA:3.40.50.1000 58 214 6.3E-21 T 23-04-2016 IPR023214 HAD-like domain DC74_RS05740 bf591b22fed5570a6cc61ebd6f473444 344 SMART SM00421 257 315 4.2E-4 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS05740 bf591b22fed5570a6cc61ebd6f473444 344 Pfam PF00196 Bacterial regulatory proteins, luxR family 267 311 1.1E-6 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS05740 bf591b22fed5570a6cc61ebd6f473444 344 SUPERFAMILY SSF46894 266 314 3.16E-8 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS05740 bf591b22fed5570a6cc61ebd6f473444 344 Gene3D G3DSA:1.10.10.10 266 312 1.5E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02850 f6d90075c25eb0f5f746312941760d7e 274 Pfam PF00248 Aldo/keto reductase family 24 260 1.3E-50 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS02850 f6d90075c25eb0f5f746312941760d7e 274 Gene3D G3DSA:3.20.20.100 5 271 1.4E-105 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS02850 f6d90075c25eb0f5f746312941760d7e 274 PRINTS PR00069 Aldo-keto reductase signature 159 188 7.9E-47 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS02850 f6d90075c25eb0f5f746312941760d7e 274 PRINTS PR00069 Aldo-keto reductase signature 125 142 7.9E-47 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS02850 f6d90075c25eb0f5f746312941760d7e 274 PRINTS PR00069 Aldo-keto reductase signature 93 111 7.9E-47 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS02850 f6d90075c25eb0f5f746312941760d7e 274 PRINTS PR00069 Aldo-keto reductase signature 196 220 7.9E-47 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS02850 f6d90075c25eb0f5f746312941760d7e 274 PRINTS PR00069 Aldo-keto reductase signature 37 61 7.9E-47 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DC74_RS02850 f6d90075c25eb0f5f746312941760d7e 274 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 23-04-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 DC74_RS02850 f6d90075c25eb0f5f746312941760d7e 274 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 23-04-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 DC74_RS02850 f6d90075c25eb0f5f746312941760d7e 274 SUPERFAMILY SSF51430 6 268 5.5E-96 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS02850 f6d90075c25eb0f5f746312941760d7e 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 23-04-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 DC74_RS02850 f6d90075c25eb0f5f746312941760d7e 274 PANTHER PTHR11732 4 274 3.7E-144 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 PANTHER PTHR26402 7 219 1.1E-108 T 23-04-2016 DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 SMART SM00421 157 214 3.8E-24 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 SUPERFAMILY SSF46894 149 221 3.3E-22 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 Gene3D G3DSA:3.40.50.2300 6 159 3.8E-42 T 23-04-2016 DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 SUPERFAMILY SSF52172 7 139 9.25E-35 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 Pfam PF00072 Response regulator receiver domain 9 120 3.5E-28 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 SMART SM00448 7 120 4.5E-32 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 Gene3D G3DSA:1.10.10.10 160 219 3.0E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 PANTHER PTHR26402:SF564 7 219 1.1E-108 T 23-04-2016 DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 8.1E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 8.1E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 8.1E-13 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS29035 997f6f7e1c3868aaa05b5491d76b0134 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 214 4.7E-18 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS02610 8e8e4c5d20912477be5792e64ffb1591 269 PANTHER PTHR13887:SF14 2 249 9.4E-18 T 23-04-2016 DC74_RS02610 8e8e4c5d20912477be5792e64ffb1591 269 Pfam PF13462 Thioredoxin 75 230 1.8E-16 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS02610 8e8e4c5d20912477be5792e64ffb1591 269 SUPERFAMILY SSF52833 75 228 6.1E-15 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS02610 8e8e4c5d20912477be5792e64ffb1591 269 Gene3D G3DSA:3.40.30.10 73 242 4.7E-20 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS02610 8e8e4c5d20912477be5792e64ffb1591 269 PANTHER PTHR13887 2 249 9.4E-18 T 23-04-2016 DC74_RS23380 68da27daac7be31fd2339e8e7df98fc7 134 PANTHER PTHR11717 14 131 1.6E-29 T 23-04-2016 DC74_RS23380 68da27daac7be31fd2339e8e7df98fc7 134 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 14 124 4.9E-17 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS23380 68da27daac7be31fd2339e8e7df98fc7 134 PANTHER PTHR11717:SF18 14 131 1.6E-29 T 23-04-2016 DC74_RS23380 68da27daac7be31fd2339e8e7df98fc7 134 SMART SM00226 14 127 2.3E-31 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS23380 68da27daac7be31fd2339e8e7df98fc7 134 SUPERFAMILY SSF52788 14 125 7.85E-29 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS23380 68da27daac7be31fd2339e8e7df98fc7 134 Gene3D G3DSA:3.40.50.270 13 125 3.2E-33 T 23-04-2016 DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 SUPERFAMILY SSF52402 242 387 1.19E-70 T 23-04-2016 DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 SUPERFAMILY SSF52402 485 624 1.19E-70 T 23-04-2016 DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 Pfam PF00733 Asparagine synthase 242 630 4.1E-93 T 23-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 Gene3D G3DSA:3.40.50.620 240 383 8.5E-77 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 Gene3D G3DSA:3.40.50.620 480 630 8.5E-77 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 PIRSF PIRSF001589 1 644 6.2E-152 T 23-04-2016 DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 SUPERFAMILY SSF56235 1 222 1.97E-60 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 PANTHER PTHR11772 2 389 2.8E-185 T 23-04-2016 DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 PANTHER PTHR11772 476 641 2.8E-185 T 23-04-2016 DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 PANTHER PTHR11772:SF10 2 389 2.8E-185 T 23-04-2016 DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 PANTHER PTHR11772:SF10 476 641 2.8E-185 T 23-04-2016 DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 563 8.8E-126 T 23-04-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|UniPathway: UPA00134 DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 Gene3D G3DSA:3.60.20.10 17 224 5.6E-77 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS05455 d54c0a4bba5b8dc69d2fe18f246d95fb 644 Pfam PF13537 Glutamine amidotransferase domain 48 165 1.2E-42 T 23-04-2016 IPR017932 Glutamine amidotransferase type 2 domain DC74_RS11145 c269415b526371a387448d250fce8495 342 SUPERFAMILY SSF53807 49 335 6.28E-32 T 23-04-2016 DC74_RS11145 c269415b526371a387448d250fce8495 342 Pfam PF01497 Periplasmic binding protein 71 313 4.4E-17 T 23-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 DC74_RS11145 c269415b526371a387448d250fce8495 342 Gene3D G3DSA:3.40.50.1980 193 335 6.1E-14 T 23-04-2016 DC74_RS11145 c269415b526371a387448d250fce8495 342 Gene3D G3DSA:3.40.50.1980 49 181 1.4E-12 T 23-04-2016 DC74_RS01385 bfedc2865c411dfa26886b208e9f4a3c 741 SUPERFAMILY SSF69318 437 714 4.05E-22 T 23-04-2016 DC74_RS01385 bfedc2865c411dfa26886b208e9f4a3c 741 Gene3D G3DSA:2.115.10.10 642 719 4.1E-7 T 23-04-2016 IPR023294 Tachylectin 2 DC74_RS01385 bfedc2865c411dfa26886b208e9f4a3c 741 Gene3D G3DSA:2.115.10.10 491 641 1.0E-16 T 23-04-2016 IPR023294 Tachylectin 2 DC74_RS10465 75c7d319d4d14d2ed4d5874157ed6e94 196 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 190 9.7E-77 T 23-04-2016 IPR021441 Protein of unknown function DUF3090 DC74_RS10465 75c7d319d4d14d2ed4d5874157ed6e94 196 Pfam PF11290 Protein of unknown function (DUF3090) 7 186 1.1E-66 T 23-04-2016 IPR021441 Protein of unknown function DUF3090 DC74_RS20565 cc5066696f0d75b9a77da16ece773c8f 489 Gene3D G3DSA:3.40.710.10 144 487 1.2E-93 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS20565 cc5066696f0d75b9a77da16ece773c8f 489 SUPERFAMILY SSF56601 101 487 3.59E-85 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS20565 cc5066696f0d75b9a77da16ece773c8f 489 Gene3D G3DSA:3.90.1310.10 74 143 5.2E-7 T 23-04-2016 DC74_RS20565 cc5066696f0d75b9a77da16ece773c8f 489 PANTHER PTHR30627:SF3 1 489 4.4E-177 T 23-04-2016 DC74_RS20565 cc5066696f0d75b9a77da16ece773c8f 489 PANTHER PTHR30627 1 489 4.4E-177 T 23-04-2016 DC74_RS20565 cc5066696f0d75b9a77da16ece773c8f 489 Pfam PF00905 Penicillin binding protein transpeptidase domain 156 482 1.7E-71 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS03855 47667fe02c6fd9649feab43a12a7d58f 225 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 1 221 2.9E-56 T 23-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 DC74_RS03855 47667fe02c6fd9649feab43a12a7d58f 225 PANTHER PTHR31801 1 216 6.1E-52 T 23-04-2016 DC74_RS03855 47667fe02c6fd9649feab43a12a7d58f 225 SUPERFAMILY SSF51219 1 223 6.54E-55 T 23-04-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain DC74_RS03855 47667fe02c6fd9649feab43a12a7d58f 225 Pfam PF01987 Mitochondrial biogenesis AIM24 4 207 5.5E-49 T 23-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 DC74_RS03855 47667fe02c6fd9649feab43a12a7d58f 225 Gene3D G3DSA:3.60.160.10 1 223 1.7E-61 T 23-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 DC74_RS12260 6a486ca5afa32bca9de2cf2a5d1a989b 188 Gene3D G3DSA:2.30.110.10 16 153 8.0E-10 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS12260 6a486ca5afa32bca9de2cf2a5d1a989b 188 SUPERFAMILY SSF50475 14 131 4.23E-12 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS00385 67bbd590c0b9e7719a1affeed8d1be05 190 PANTHER PTHR13256 3 189 7.3E-20 T 23-04-2016 DC74_RS00385 67bbd590c0b9e7719a1affeed8d1be05 190 SUPERFAMILY SSF55729 3 176 3.61E-23 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS00385 67bbd590c0b9e7719a1affeed8d1be05 190 Gene3D G3DSA:3.40.630.30 4 188 5.5E-29 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS00385 67bbd590c0b9e7719a1affeed8d1be05 190 Pfam PF13302 Acetyltransferase (GNAT) domain 12 131 5.9E-15 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 7.0E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.0E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.0E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 7.0E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 7.0E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.0E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 Gene3D G3DSA:3.40.50.720 3 248 2.6E-84 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 PANTHER PTHR24322 11 140 4.8E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 PANTHER PTHR24322 156 187 4.8E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.0E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.0E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.0E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 SUPERFAMILY SSF51735 3 248 7.72E-80 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00605 e35f8a0abaad06ba1ed2affa2f9a2248 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 247 8.2E-69 T 23-04-2016 DC74_RS21690 e465c4b034a279de8e983a2f1faf2fe7 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 53 13.295 T 23-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 DC74_RS21690 e465c4b034a279de8e983a2f1faf2fe7 56 SUPERFAMILY SSF57829 1 38 4.64E-9 T 23-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 DC74_RS21690 e465c4b034a279de8e983a2f1faf2fe7 56 Pfam PF01783 Ribosomal L32p protein family 2 46 9.4E-13 T 23-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 DC74_RS21690 e465c4b034a279de8e983a2f1faf2fe7 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 35 9.9E-11 T 23-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 DC74_RS23450 c5017fbfef1e0b2e0ade548459cecb37 95 SUPERFAMILY SSF47413 6 76 4.22E-15 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS23450 c5017fbfef1e0b2e0ade548459cecb37 95 Pfam PF13560 Helix-turn-helix domain 16 77 1.1E-11 T 23-04-2016 DC74_RS23450 c5017fbfef1e0b2e0ade548459cecb37 95 SMART SM00530 20 74 2.1E-8 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS23450 c5017fbfef1e0b2e0ade548459cecb37 95 PANTHER PTHR10245 1 74 6.8E-22 T 23-04-2016 DC74_RS23450 c5017fbfef1e0b2e0ade548459cecb37 95 PANTHER PTHR10245:SF59 1 74 6.8E-22 T 23-04-2016 DC74_RS23450 c5017fbfef1e0b2e0ade548459cecb37 95 Gene3D G3DSA:1.10.260.40 9 75 2.0E-24 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS10220 33da6694c40528dea70c35cce6946547 283 PANTHER PTHR30157 1 266 9.8E-103 T 23-04-2016 DC74_RS10220 33da6694c40528dea70c35cce6946547 283 Pfam PF04954 Siderophore-interacting protein 139 256 2.0E-39 T 23-04-2016 IPR007037 Siderophore-interacting protein DC74_RS10220 33da6694c40528dea70c35cce6946547 283 Gene3D G3DSA:2.40.30.10 10 131 5.1E-37 T 23-04-2016 DC74_RS10220 33da6694c40528dea70c35cce6946547 283 SUPERFAMILY SSF63380 12 133 1.97E-13 T 23-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 DC74_RS10220 33da6694c40528dea70c35cce6946547 283 PANTHER PTHR30157:SF1 1 266 9.8E-103 T 23-04-2016 DC74_RS10220 33da6694c40528dea70c35cce6946547 283 Gene3D G3DSA:3.40.50.80 134 277 1.7E-52 T 23-04-2016 DC74_RS10220 33da6694c40528dea70c35cce6946547 283 Pfam PF08021 Siderophore-interacting FAD-binding domain 18 132 1.8E-38 T 23-04-2016 IPR013113 FAD-binding 9, siderophore-interacting DC74_RS29065 2e97f6588bae7a62f69be7e14650545b 266 Gene3D G3DSA:2.70.70.10 108 260 1.1E-43 T 23-04-2016 DC74_RS29065 2e97f6588bae7a62f69be7e14650545b 266 Pfam PF01551 Peptidase family M23 158 255 5.5E-30 T 23-04-2016 IPR016047 Peptidase M23 DC74_RS29065 2e97f6588bae7a62f69be7e14650545b 266 PANTHER PTHR21666 69 265 6.1E-42 T 23-04-2016 DC74_RS29065 2e97f6588bae7a62f69be7e14650545b 266 SUPERFAMILY SSF51261 91 259 4.5E-44 T 23-04-2016 IPR011055 Duplicated hybrid motif DC74_RS09480 e7f07092ab3f8ff632029bef02b2086c 368 SUPERFAMILY SSF53092 5 137 8.27E-19 T 23-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal DC74_RS09480 e7f07092ab3f8ff632029bef02b2086c 368 PANTHER PTHR10804:SF109 119 366 1.1E-108 T 23-04-2016 DC74_RS09480 e7f07092ab3f8ff632029bef02b2086c 368 SUPERFAMILY SSF55920 137 366 1.31E-59 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS09480 e7f07092ab3f8ff632029bef02b2086c 368 Gene3D G3DSA:3.40.350.10 5 136 2.2E-13 T 23-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal DC74_RS09480 e7f07092ab3f8ff632029bef02b2086c 368 PANTHER PTHR10804 119 366 1.1E-108 T 23-04-2016 DC74_RS09480 e7f07092ab3f8ff632029bef02b2086c 368 Pfam PF00557 Metallopeptidase family M24 146 348 3.3E-46 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS09480 e7f07092ab3f8ff632029bef02b2086c 368 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 138 1.7E-11 T 23-04-2016 IPR000587 Creatinase, N-terminal GO:0016787 DC74_RS09480 e7f07092ab3f8ff632029bef02b2086c 368 Gene3D G3DSA:3.90.230.10 138 365 1.8E-58 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS30105 d7cf87e6605092a8be9ebc54886a8bf2 228 PIRSF PIRSF029950 1 215 1.7E-64 T 23-04-2016 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 DC74_RS30105 d7cf87e6605092a8be9ebc54886a8bf2 228 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 1 40 1.4E-13 T 23-04-2016 IPR013422 CRISPR-associated protein Cas5, N-terminal DC74_RS30105 d7cf87e6605092a8be9ebc54886a8bf2 228 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 2 201 6.0E-32 T 23-04-2016 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 DC74_RS30105 d7cf87e6605092a8be9ebc54886a8bf2 228 TIGRFAM TIGR01876 cas_Cas5d: CRISPR-associated protein Cas5, subtype I-C/DVULG 1 206 2.4E-48 T 23-04-2016 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 DC74_RS01345 9810fab94ffa94f6c4d415e0dc1c724a 251 SUPERFAMILY SSF53474 3 249 1.23E-43 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01345 9810fab94ffa94f6c4d415e0dc1c724a 251 PANTHER PTHR10992 2 251 4.2E-36 T 23-04-2016 DC74_RS01345 9810fab94ffa94f6c4d415e0dc1c724a 251 Gene3D G3DSA:3.40.50.1820 3 250 3.2E-43 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS01345 9810fab94ffa94f6c4d415e0dc1c724a 251 Pfam PF12697 Alpha/beta hydrolase family 15 242 5.0E-15 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS24175 69515bd0f407990e13f5d8f8280ab1dd 343 Pfam PF01476 LysM domain 195 238 1.3E-10 T 23-04-2016 IPR018392 LysM domain DC74_RS24175 69515bd0f407990e13f5d8f8280ab1dd 343 Gene3D G3DSA:1.10.101.10 277 333 3.2E-4 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS24175 69515bd0f407990e13f5d8f8280ab1dd 343 Gene3D G3DSA:3.10.350.10 195 239 1.6E-10 T 23-04-2016 IPR018392 LysM domain DC74_RS24175 69515bd0f407990e13f5d8f8280ab1dd 343 SUPERFAMILY SSF54106 193 238 1.02E-6 T 23-04-2016 IPR018392 LysM domain DC74_RS24175 69515bd0f407990e13f5d8f8280ab1dd 343 SUPERFAMILY SSF54001 21 143 4.9E-5 T 23-04-2016 DC74_RS24175 69515bd0f407990e13f5d8f8280ab1dd 343 Pfam PF05257 CHAP domain 44 121 1.7E-10 T 23-04-2016 IPR007921 CHAP domain DC74_RS24175 69515bd0f407990e13f5d8f8280ab1dd 343 SMART SM00257 193 238 3.0E-11 T 23-04-2016 IPR018392 LysM domain DC74_RS13540 71f09d7da59c886e06dfbc5289856908 221 PANTHER PTHR30246 24 219 1.6E-98 T 23-04-2016 DC74_RS13540 71f09d7da59c886e06dfbc5289856908 221 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 137 150 - T 23-04-2016 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 DC74_RS13540 71f09d7da59c886e06dfbc5289856908 221 Gene3D G3DSA:3.20.20.70 21 218 1.5E-72 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS13540 71f09d7da59c886e06dfbc5289856908 221 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 49 58 - T 23-04-2016 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562|UniPathway: UPA00227|UniPathway: UPA00856 DC74_RS13540 71f09d7da59c886e06dfbc5289856908 221 PANTHER PTHR30246:SF0 24 219 1.6E-98 T 23-04-2016 DC74_RS13540 71f09d7da59c886e06dfbc5289856908 221 Pfam PF01081 KDPG and KHG aldolase 20 212 9.8E-69 T 23-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 DC74_RS13540 71f09d7da59c886e06dfbc5289856908 221 SUPERFAMILY SSF51569 20 218 5.31E-64 T 23-04-2016 DC74_RS13540 71f09d7da59c886e06dfbc5289856908 221 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 20 218 5.6E-73 T 23-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 DC74_RS33945 efa09545495ff10d56acf9c3abc2702a 305 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 42 241 5.1E-22 T 23-04-2016 IPR018713 Domain of unknown function DUF2236 DC74_RS33945 efa09545495ff10d56acf9c3abc2702a 305 PANTHER PTHR36124 3 280 2.0E-152 T 23-04-2016 DC74_RS33945 efa09545495ff10d56acf9c3abc2702a 305 PANTHER PTHR36124:SF2 3 280 2.0E-152 T 23-04-2016 DC74_RS17880 95b50368dbe3026cdaaf8adddb710035 172 SUPERFAMILY SSF81330 16 140 2.35E-24 T 23-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 DC74_RS17880 95b50368dbe3026cdaaf8adddb710035 172 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 8 144 4.3E-23 T 23-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 DC74_RS17880 95b50368dbe3026cdaaf8adddb710035 172 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 8 143 8.7E-35 T 23-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 DC74_RS17880 95b50368dbe3026cdaaf8adddb710035 172 PANTHER PTHR30266 6 151 3.4E-35 T 23-04-2016 DC74_RS17880 95b50368dbe3026cdaaf8adddb710035 172 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 93 101 1.6E-5 T 23-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 DC74_RS17880 95b50368dbe3026cdaaf8adddb710035 172 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 103 112 1.6E-5 T 23-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 DC74_RS17880 95b50368dbe3026cdaaf8adddb710035 172 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 10 24 1.6E-5 T 23-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 DC74_RS17880 95b50368dbe3026cdaaf8adddb710035 172 PANTHER PTHR30266:SF2 6 151 3.4E-35 T 23-04-2016 DC74_RS25630 87ae6d651bb6e5f1bf4f56b43006474e 89 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 22 82 13.348 T 23-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 DC74_RS25630 87ae6d651bb6e5f1bf4f56b43006474e 89 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 23 77 8.7E-19 T 23-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 DC74_RS25630 87ae6d651bb6e5f1bf4f56b43006474e 89 SUPERFAMILY SSF116842 19 77 4.84E-15 T 23-04-2016 DC74_RS25630 87ae6d651bb6e5f1bf4f56b43006474e 89 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 20 61 1.0E-14 T 23-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 DC74_RS25630 87ae6d651bb6e5f1bf4f56b43006474e 89 Pfam PF02609 Exonuclease VII small subunit 23 72 1.8E-16 T 23-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 DC74_RS25630 87ae6d651bb6e5f1bf4f56b43006474e 89 PANTHER PTHR34137 10 78 2.3E-19 T 23-04-2016 DC74_RS25630 87ae6d651bb6e5f1bf4f56b43006474e 89 Gene3D G3DSA:1.10.287.1040 19 82 1.9E-21 T 23-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 DC74_RS25630 87ae6d651bb6e5f1bf4f56b43006474e 89 PIRSF PIRSF006488 11 89 4.6E-24 T 23-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 DC74_RS28810 27b29a9d5b62467027abdcab8497ce35 215 Gene3D G3DSA:1.10.3720.10 6 211 2.0E-40 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28810 27b29a9d5b62467027abdcab8497ce35 215 PANTHER PTHR30614 1 215 1.4E-58 T 23-04-2016 DC74_RS28810 27b29a9d5b62467027abdcab8497ce35 215 SUPERFAMILY SSF161098 10 197 2.35E-37 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28810 27b29a9d5b62467027abdcab8497ce35 215 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 106 6.9E-19 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 DC74_RS28810 27b29a9d5b62467027abdcab8497ce35 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 211 1.4E-16 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS04020 ce24fab2300a5d8003b1d8d1468703dc 132 PANTHER PTHR30007:SF22 4 122 1.0E-29 T 23-04-2016 DC74_RS04020 ce24fab2300a5d8003b1d8d1468703dc 132 PANTHER PTHR30007 4 122 1.0E-29 T 23-04-2016 DC74_RS04020 ce24fab2300a5d8003b1d8d1468703dc 132 Pfam PF13586 Transposase DDE domain 26 122 3.4E-17 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS00680 ce24fab2300a5d8003b1d8d1468703dc 132 PANTHER PTHR30007:SF22 4 122 1.0E-29 T 23-04-2016 DC74_RS00680 ce24fab2300a5d8003b1d8d1468703dc 132 PANTHER PTHR30007 4 122 1.0E-29 T 23-04-2016 DC74_RS00680 ce24fab2300a5d8003b1d8d1468703dc 132 Pfam PF13586 Transposase DDE domain 26 122 3.4E-17 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS20520 1dd733328b8e4f0df99d217512d95220 120 Pfam PF01638 HxlR-like helix-turn-helix 23 108 2.0E-24 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS20520 1dd733328b8e4f0df99d217512d95220 120 PANTHER PTHR33204 1 108 4.7E-33 T 23-04-2016 DC74_RS20520 1dd733328b8e4f0df99d217512d95220 120 Gene3D G3DSA:1.10.10.10 15 117 7.7E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20520 1dd733328b8e4f0df99d217512d95220 120 PANTHER PTHR33204:SF13 1 108 4.7E-33 T 23-04-2016 DC74_RS20520 1dd733328b8e4f0df99d217512d95220 120 SUPERFAMILY SSF46785 15 117 1.14E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01505 d38ef29c1613b433347b0b7b9372822a 391 PANTHER PTHR23501 4 382 8.9E-144 T 23-04-2016 DC74_RS01505 d38ef29c1613b433347b0b7b9372822a 391 Gene3D G3DSA:1.20.1250.20 212 385 3.9E-14 T 23-04-2016 DC74_RS01505 d38ef29c1613b433347b0b7b9372822a 391 Gene3D G3DSA:1.20.1250.20 4 182 7.9E-22 T 23-04-2016 DC74_RS01505 d38ef29c1613b433347b0b7b9372822a 391 PANTHER PTHR23501:SF79 4 382 8.9E-144 T 23-04-2016 DC74_RS01505 d38ef29c1613b433347b0b7b9372822a 391 Pfam PF07690 Major Facilitator Superfamily 14 229 1.8E-19 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS01505 d38ef29c1613b433347b0b7b9372822a 391 SUPERFAMILY SSF103473 4 382 2.35E-50 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS33965 198725b5cffb0c5cc39eba7b7aa5b816 142 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 12 135 2.2E-40 T 23-04-2016 IPR019920 F420-binding domain, putative DC74_RS33965 198725b5cffb0c5cc39eba7b7aa5b816 142 Gene3D G3DSA:2.30.110.10 4 137 2.5E-39 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS33965 198725b5cffb0c5cc39eba7b7aa5b816 142 PANTHER PTHR35176 1 142 3.0E-47 T 23-04-2016 DC74_RS33965 198725b5cffb0c5cc39eba7b7aa5b816 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 88 1.1E-17 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS33965 198725b5cffb0c5cc39eba7b7aa5b816 142 SUPERFAMILY SSF50475 3 136 4.58E-31 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS33965 198725b5cffb0c5cc39eba7b7aa5b816 142 PANTHER PTHR35176:SF1 1 142 3.0E-47 T 23-04-2016 DC74_RS01695 cb4d15d3a200fae690c04f4347484c28 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 94 4.5E-9 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS01695 cb4d15d3a200fae690c04f4347484c28 332 SUPERFAMILY SSF50129 2 152 7.86E-35 T 23-04-2016 IPR011032 GroES-like DC74_RS01695 cb4d15d3a200fae690c04f4347484c28 332 PANTHER PTHR11695 16 332 2.2E-82 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS01695 cb4d15d3a200fae690c04f4347484c28 332 SUPERFAMILY SSF51735 118 275 1.23E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01695 cb4d15d3a200fae690c04f4347484c28 332 Gene3D G3DSA:3.40.50.720 153 259 5.4E-22 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01695 cb4d15d3a200fae690c04f4347484c28 332 Gene3D G3DSA:3.90.180.10 3 152 4.5E-40 T 23-04-2016 IPR011032 GroES-like DC74_RS01695 cb4d15d3a200fae690c04f4347484c28 332 Pfam PF00107 Zinc-binding dehydrogenase 159 273 8.0E-20 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS01695 cb4d15d3a200fae690c04f4347484c28 332 SMART SM00829 11 328 1.2E-38 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS25970 364167c199081a1ea48444c0360a0563 227 PANTHER PTHR10509:SF18 44 226 2.6E-86 T 23-04-2016 DC74_RS25970 364167c199081a1ea48444c0360a0563 227 Gene3D G3DSA:3.40.50.150 39 226 4.3E-49 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS25970 364167c199081a1ea48444c0360a0563 227 Pfam PF01596 O-methyltransferase 52 223 1.0E-22 T 23-04-2016 IPR002935 O-methyltransferase, family 3 GO:0008171 DC74_RS25970 364167c199081a1ea48444c0360a0563 227 PANTHER PTHR10509 44 226 2.6E-86 T 23-04-2016 DC74_RS25970 364167c199081a1ea48444c0360a0563 227 SUPERFAMILY SSF53335 49 226 5.31E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS35680 687ac4ea367ec967cf920e9c24c8ba24 242 Gene3D G3DSA:3.40.50.880 22 213 5.4E-19 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS35680 687ac4ea367ec967cf920e9c24c8ba24 242 PANTHER PTHR21343 6 241 3.6E-99 T 23-04-2016 DC74_RS35680 687ac4ea367ec967cf920e9c24c8ba24 242 PANTHER PTHR21343:SF9 6 241 3.6E-99 T 23-04-2016 DC74_RS35680 687ac4ea367ec967cf920e9c24c8ba24 242 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 7 202 1.7E-36 T 23-04-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 DC74_RS35680 687ac4ea367ec967cf920e9c24c8ba24 242 SUPERFAMILY SSF52317 20 214 1.08E-17 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS36460 b840d0bacf049faf9c960895c046b93f 310 PANTHER PTHR40761 2 306 1.1E-67 T 23-04-2016 DC74_RS36460 b840d0bacf049faf9c960895c046b93f 310 PANTHER PTHR40761:SF1 2 306 1.1E-67 T 23-04-2016 DC74_RS06340 2e4bba3103bd66d993b627e19497aa93 502 PIRSF PIRSF006060 10 492 9.2E-53 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS06340 2e4bba3103bd66d993b627e19497aa93 502 PANTHER PTHR11785 457 492 2.1E-32 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS06340 2e4bba3103bd66d993b627e19497aa93 502 PANTHER PTHR11785 11 440 2.1E-32 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS06340 2e4bba3103bd66d993b627e19497aa93 502 Pfam PF13520 Amino acid permease 38 408 4.3E-34 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS10715 a1dcf8db4a8edaa3320b7608ef846480 366 PANTHER PTHR11695:SF269 14 366 1.4E-111 T 23-04-2016 DC74_RS10715 a1dcf8db4a8edaa3320b7608ef846480 366 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS10715 a1dcf8db4a8edaa3320b7608ef846480 366 SMART SM00829 9 364 7.3E-11 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS10715 a1dcf8db4a8edaa3320b7608ef846480 366 Gene3D G3DSA:3.90.180.10 2 182 3.5E-56 T 23-04-2016 IPR011032 GroES-like DC74_RS10715 a1dcf8db4a8edaa3320b7608ef846480 366 PANTHER PTHR11695 14 366 1.4E-111 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS10715 a1dcf8db4a8edaa3320b7608ef846480 366 SUPERFAMILY SSF51735 152 330 6.87E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10715 a1dcf8db4a8edaa3320b7608ef846480 366 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 147 9.1E-24 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS10715 a1dcf8db4a8edaa3320b7608ef846480 366 Pfam PF00107 Zinc-binding dehydrogenase 190 317 1.0E-24 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS10715 a1dcf8db4a8edaa3320b7608ef846480 366 Gene3D G3DSA:3.40.50.720 183 308 5.1E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10715 a1dcf8db4a8edaa3320b7608ef846480 366 SUPERFAMILY SSF50129 2 183 2.28E-50 T 23-04-2016 IPR011032 GroES-like DC74_RS04785 53f741d12aeb5d37f077c28ca810897e 153 SUPERFAMILY SSF69118 8 150 1.44E-37 T 23-04-2016 IPR029032 AhpD-like DC74_RS04785 53f741d12aeb5d37f077c28ca810897e 153 Gene3D G3DSA:1.20.1290.10 6 151 1.3E-42 T 23-04-2016 IPR029032 AhpD-like DC74_RS04785 53f741d12aeb5d37f077c28ca810897e 153 Pfam PF02627 Carboxymuconolactone decarboxylase family 23 99 2.2E-19 T 23-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS04785 53f741d12aeb5d37f077c28ca810897e 153 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 35 84 4.0E-19 T 23-04-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS05430 c152dbf46c768114647916bcfaabdabe 492 PANTHER PTHR30576 8 492 3.4E-214 T 23-04-2016 DC74_RS05430 c152dbf46c768114647916bcfaabdabe 492 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 40 492 1.6E-119 T 23-04-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase DC74_RS05430 c152dbf46c768114647916bcfaabdabe 492 Pfam PF02397 Bacterial sugar transferase 299 486 1.4E-55 T 23-04-2016 IPR003362 Bacterial sugar transferase DC74_RS05430 c152dbf46c768114647916bcfaabdabe 492 PANTHER PTHR30576:SF4 8 492 3.4E-214 T 23-04-2016 DC74_RS05430 c152dbf46c768114647916bcfaabdabe 492 Pfam PF13727 CoA-binding domain 109 227 7.2E-6 T 23-04-2016 DC74_RS04230 78479989a0de2f4cde6b334810a5d744 234 SMART SM00862 120 192 1.0E-17 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS04230 78479989a0de2f4cde6b334810a5d744 234 Gene3D G3DSA:3.40.50.2300 3 96 1.4E-21 T 23-04-2016 DC74_RS04230 78479989a0de2f4cde6b334810a5d744 234 SUPERFAMILY SSF52172 3 141 1.85E-23 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS04230 78479989a0de2f4cde6b334810a5d744 234 PANTHER PTHR26402:SF578 1 205 1.5E-52 T 23-04-2016 DC74_RS04230 78479989a0de2f4cde6b334810a5d744 234 SMART SM00448 1 87 7.4E-6 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS04230 78479989a0de2f4cde6b334810a5d744 234 Gene3D G3DSA:1.10.10.10 101 193 9.7E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04230 78479989a0de2f4cde6b334810a5d744 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 123 192 8.8E-18 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS04230 78479989a0de2f4cde6b334810a5d744 234 Pfam PF00072 Response regulator receiver domain 3 88 2.9E-16 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS04230 78479989a0de2f4cde6b334810a5d744 234 PANTHER PTHR26402 1 205 1.5E-52 T 23-04-2016 DC74_RS34840 4e51f048f61bde926d819c308de572cf 444 PANTHER PTHR23519 2 444 1.6E-81 T 23-04-2016 DC74_RS34840 4e51f048f61bde926d819c308de572cf 444 Pfam PF11700 Vacuole effluxer Atg22 like 16 436 1.0E-85 T 23-04-2016 IPR024671 Autophagy-related protein 22-like DC74_RS34840 4e51f048f61bde926d819c308de572cf 444 Gene3D G3DSA:1.20.1250.20 33 219 1.9E-7 T 23-04-2016 DC74_RS34840 4e51f048f61bde926d819c308de572cf 444 Gene3D G3DSA:1.20.1250.20 244 428 1.7E-20 T 23-04-2016 DC74_RS34840 4e51f048f61bde926d819c308de572cf 444 SUPERFAMILY SSF103473 22 431 1.03E-37 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS32475 1fbdbe1268d76f2f5a0b2b830077d6a2 185 SUPERFAMILY SSF46689 1 67 1.74E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS32475 1fbdbe1268d76f2f5a0b2b830077d6a2 185 SUPERFAMILY SSF48498 69 178 7.26E-10 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS32475 1fbdbe1268d76f2f5a0b2b830077d6a2 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 44 8.9E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS32475 1fbdbe1268d76f2f5a0b2b830077d6a2 185 Pfam PF13977 Bacterial transcriptional repressor 70 179 4.2E-13 T 23-04-2016 DC74_RS32475 1fbdbe1268d76f2f5a0b2b830077d6a2 185 Gene3D G3DSA:1.10.357.10 2 177 2.8E-24 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS32475 1fbdbe1268d76f2f5a0b2b830077d6a2 185 PANTHER PTHR30055 1 182 6.2E-15 T 23-04-2016 DC74_RS14655 4156f1a51a7403b03bc796ac07bd6ad3 121 PANTHER PTHR37694 1 113 2.3E-18 T 23-04-2016 DC74_RS14655 4156f1a51a7403b03bc796ac07bd6ad3 121 SUPERFAMILY SSF51182 19 103 3.56E-8 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS14655 4156f1a51a7403b03bc796ac07bd6ad3 121 Gene3D G3DSA:2.60.120.10 12 102 6.3E-11 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS00860 73047abbacb1d35ab38e033d2ab27709 215 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 106 194 1.2E-17 T 23-04-2016 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 DC74_RS00860 73047abbacb1d35ab38e033d2ab27709 215 PANTHER PTHR12714 85 215 5.5E-19 T 23-04-2016 DC74_RS11230 862e1035d74d3d1bc3246cde8a42b3e5 255 PANTHER PTHR30269:SF10 1 254 1.1E-99 T 23-04-2016 DC74_RS11230 862e1035d74d3d1bc3246cde8a42b3e5 255 PANTHER PTHR30269 1 254 1.1E-99 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 DC74_RS11230 862e1035d74d3d1bc3246cde8a42b3e5 255 Pfam PF01925 Sulfite exporter TauE/SafE 10 251 2.0E-38 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 DC74_RS34305 dbf2747f74b8ca317b9ba81a81f1c6d0 248 Pfam PF10099 Anti-sigma-K factor rskA 58 243 6.9E-31 T 23-04-2016 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 DC74_RS34305 dbf2747f74b8ca317b9ba81a81f1c6d0 248 Pfam PF13490 Putative zinc-finger 11 37 2.9E-6 T 23-04-2016 IPR027383 Putative zinc-finger DC74_RS34305 dbf2747f74b8ca317b9ba81a81f1c6d0 248 PANTHER PTHR37461:SF1 1 243 1.0E-33 T 23-04-2016 DC74_RS34305 dbf2747f74b8ca317b9ba81a81f1c6d0 248 PANTHER PTHR37461 1 243 1.0E-33 T 23-04-2016 DC74_RS00030 da2b4a6b738e61c09840ac3f3a1ae108 288 PIRSF PIRSF000103 1 288 9.8E-37 T 23-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 DC74_RS00030 da2b4a6b738e61c09840ac3f3a1ae108 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 157 6.7E-24 T 23-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 DC74_RS00030 da2b4a6b738e61c09840ac3f3a1ae108 288 Gene3D G3DSA:3.40.50.720 1 156 3.1E-36 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00030 da2b4a6b738e61c09840ac3f3a1ae108 288 SUPERFAMILY SSF51735 4 156 3.31E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00030 da2b4a6b738e61c09840ac3f3a1ae108 288 PANTHER PTHR22981 6 287 1.6E-53 T 23-04-2016 DC74_RS00030 da2b4a6b738e61c09840ac3f3a1ae108 288 PANTHER PTHR22981:SF76 6 287 1.6E-53 T 23-04-2016 DC74_RS00030 da2b4a6b738e61c09840ac3f3a1ae108 288 Gene3D G3DSA:1.10.1040.10 186 286 4.4E-5 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DC74_RS13715 ff57fbd50384c0956081804b05a55195 179 Gene3D G3DSA:1.10.1740.10 4 98 3.0E-12 T 23-04-2016 DC74_RS13715 ff57fbd50384c0956081804b05a55195 179 SUPERFAMILY SSF88946 4 81 2.59E-11 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS13715 ff57fbd50384c0956081804b05a55195 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 161 2.9E-17 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS13715 ff57fbd50384c0956081804b05a55195 179 Gene3D G3DSA:1.10.10.10 106 163 1.1E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS13715 ff57fbd50384c0956081804b05a55195 179 Pfam PF08281 Sigma-70, region 4 108 158 1.2E-11 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS13715 ff57fbd50384c0956081804b05a55195 179 PANTHER PTHR30173 4 166 4.4E-24 T 23-04-2016 DC74_RS13715 ff57fbd50384c0956081804b05a55195 179 Pfam PF04542 Sigma-70 region 2 11 73 4.4E-6 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS13715 ff57fbd50384c0956081804b05a55195 179 SUPERFAMILY SSF88659 106 162 2.43E-12 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS16270 f94b9ec6a0b376929b524d6ca0df10a2 263 PANTHER PTHR36833 3 263 2.1E-100 T 23-04-2016 DC74_RS16270 f94b9ec6a0b376929b524d6ca0df10a2 263 Pfam PF06182 ABC-2 family transporter protein 33 262 3.7E-57 T 23-04-2016 IPR010390 Protein of unknown function DUF990 DC74_RS16270 f94b9ec6a0b376929b524d6ca0df10a2 263 PANTHER PTHR36833:SF1 3 263 2.1E-100 T 23-04-2016 DC74_RS08880 f55140a55db6692ca2c91b137487d2ac 318 Pfam PF00480 ROK family 7 307 1.5E-60 T 23-04-2016 IPR000600 ROK family DC74_RS08880 f55140a55db6692ca2c91b137487d2ac 318 Gene3D G3DSA:3.30.420.40 7 140 1.2E-37 T 23-04-2016 DC74_RS08880 f55140a55db6692ca2c91b137487d2ac 318 ProSitePatterns PS01125 ROK family signature. 138 165 - T 23-04-2016 IPR000600 ROK family DC74_RS08880 f55140a55db6692ca2c91b137487d2ac 318 PANTHER PTHR18964:SF124 7 305 9.0E-117 T 23-04-2016 DC74_RS08880 f55140a55db6692ca2c91b137487d2ac 318 Gene3D G3DSA:3.30.420.40 141 291 2.4E-47 T 23-04-2016 DC74_RS08880 f55140a55db6692ca2c91b137487d2ac 318 PANTHER PTHR18964 7 305 9.0E-117 T 23-04-2016 DC74_RS08880 f55140a55db6692ca2c91b137487d2ac 318 SUPERFAMILY SSF53067 7 308 7.35E-61 T 23-04-2016 DC74_RS39560 96f6dbbb35f68c34dbf5c42410e47c95 492 PANTHER PTHR30023 1 95 7.2E-56 T 23-04-2016 DC74_RS39560 96f6dbbb35f68c34dbf5c42410e47c95 492 PANTHER PTHR30023:SF0 129 483 7.2E-56 T 23-04-2016 DC74_RS39560 96f6dbbb35f68c34dbf5c42410e47c95 492 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 25 457 8.8E-44 T 23-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 DC74_RS39560 96f6dbbb35f68c34dbf5c42410e47c95 492 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 13 461 7.3E-60 T 23-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 DC74_RS39560 96f6dbbb35f68c34dbf5c42410e47c95 492 Gene3D G3DSA:3.40.710.10 3 54 4.6E-5 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS39560 96f6dbbb35f68c34dbf5c42410e47c95 492 PANTHER PTHR30023:SF0 1 95 7.2E-56 T 23-04-2016 DC74_RS39560 96f6dbbb35f68c34dbf5c42410e47c95 492 SUPERFAMILY SSF56601 2 95 6.2E-61 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS39560 96f6dbbb35f68c34dbf5c42410e47c95 492 SUPERFAMILY SSF56601 129 467 6.2E-61 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS39560 96f6dbbb35f68c34dbf5c42410e47c95 492 PANTHER PTHR30023 129 483 7.2E-56 T 23-04-2016 DC74_RS39560 96f6dbbb35f68c34dbf5c42410e47c95 492 Gene3D G3DSA:3.40.710.10 228 475 6.1E-41 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS02835 ad7d7834ec73f7e3da962d5c4d6b149d 207 PANTHER PTHR30055 2 207 1.2E-16 T 23-04-2016 DC74_RS02835 ad7d7834ec73f7e3da962d5c4d6b149d 207 Gene3D G3DSA:1.10.357.10 1 199 1.8E-41 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS02835 ad7d7834ec73f7e3da962d5c4d6b149d 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 58 3.5E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS02835 ad7d7834ec73f7e3da962d5c4d6b149d 207 Pfam PF13977 Bacterial transcriptional repressor 85 198 1.1E-12 T 23-04-2016 DC74_RS02835 ad7d7834ec73f7e3da962d5c4d6b149d 207 SUPERFAMILY SSF48498 84 199 3.08E-12 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS02835 ad7d7834ec73f7e3da962d5c4d6b149d 207 SUPERFAMILY SSF46689 2 79 1.23E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS14640 27ab20688b77e9c01bc025632c9d058e 230 PANTHER PTHR30336:SF0 11 219 1.7E-71 T 23-04-2016 DC74_RS14640 27ab20688b77e9c01bc025632c9d058e 230 PANTHER PTHR30336 11 219 1.7E-71 T 23-04-2016 DC74_RS14640 27ab20688b77e9c01bc025632c9d058e 230 Gene3D G3DSA:3.40.50.620 57 182 9.1E-12 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS14640 27ab20688b77e9c01bc025632c9d058e 230 Pfam PF02698 DUF218 domain 63 183 7.8E-25 T 23-04-2016 IPR003848 Domain of unknown function DUF218 DC74_RS31930 3875115265964ea9bd1a2315fd284820 147 PANTHER PTHR23091 1 126 1.9E-18 T 23-04-2016 DC74_RS31930 3875115265964ea9bd1a2315fd284820 147 Gene3D G3DSA:3.40.630.30 4 128 2.5E-27 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31930 3875115265964ea9bd1a2315fd284820 147 SUPERFAMILY SSF55729 2 128 1.36E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31930 3875115265964ea9bd1a2315fd284820 147 Pfam PF13673 Acetyltransferase (GNAT) domain 36 128 8.8E-17 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS08995 a50781d63ed24019b6afd3891b9b2722 261 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 146 229 1.0E-7 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS08995 a50781d63ed24019b6afd3891b9b2722 261 PANTHER PTHR12725 1 236 1.2E-30 T 23-04-2016 DC74_RS08995 a50781d63ed24019b6afd3891b9b2722 261 Pfam PF00702 haloacid dehalogenase-like hydrolase 16 224 1.3E-14 T 23-04-2016 DC74_RS08995 a50781d63ed24019b6afd3891b9b2722 261 SUPERFAMILY SSF56784 16 248 2.1E-31 T 23-04-2016 IPR023214 HAD-like domain DC74_RS08995 a50781d63ed24019b6afd3891b9b2722 261 Gene3D G3DSA:3.40.50.1000 16 44 3.4E-34 T 23-04-2016 IPR023214 HAD-like domain DC74_RS08995 a50781d63ed24019b6afd3891b9b2722 261 Gene3D G3DSA:3.40.50.1000 76 241 3.4E-34 T 23-04-2016 IPR023214 HAD-like domain DC74_RS25740 daa62350d876b5bac5f196589e366b62 253 Gene3D G3DSA:3.40.50.10320 17 246 2.6E-44 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS25740 daa62350d876b5bac5f196589e366b62 253 SUPERFAMILY SSF102588 18 238 2.62E-38 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS25740 daa62350d876b5bac5f196589e366b62 253 Pfam PF02585 GlcNAc-PI de-N-acetylase 22 151 1.1E-24 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS25740 daa62350d876b5bac5f196589e366b62 253 PANTHER PTHR12993 1 211 1.3E-31 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS35610 574879956c13a220497a6bf7bde99f1c 103 SUPERFAMILY SSF51278 1 102 9.81E-43 T 23-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35610 574879956c13a220497a6bf7bde99f1c 103 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 102 2.1E-35 T 23-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35610 574879956c13a220497a6bf7bde99f1c 103 PANTHER PTHR33569 1 102 4.7E-59 T 23-04-2016 DC74_RS35610 574879956c13a220497a6bf7bde99f1c 103 Pfam PF00699 Urease beta subunit 3 99 4.2E-38 T 23-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35610 574879956c13a220497a6bf7bde99f1c 103 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 29.097 T 23-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35610 574879956c13a220497a6bf7bde99f1c 103 PANTHER PTHR33569:SF1 1 102 4.7E-59 T 23-04-2016 DC74_RS35610 574879956c13a220497a6bf7bde99f1c 103 Gene3D G3DSA:2.10.150.10 1 102 4.1E-44 T 23-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS14055 368db04ffb6dba287864d198ba515d7a 164 Pfam PF11343 Protein of unknown function (DUF3145) 6 162 5.0E-73 T 23-04-2016 IPR021491 Protein of unknown function DUF3145 DC74_RS33515 d3d56dd37782a0b1c788f58357678193 261 SUPERFAMILY SSF52096 8 232 3.15E-65 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS33515 d3d56dd37782a0b1c788f58357678193 261 PANTHER PTHR11941:SF21 3 255 1.2E-115 T 23-04-2016 DC74_RS33515 d3d56dd37782a0b1c788f58357678193 261 Gene3D G3DSA:3.90.226.10 5 232 2.2E-67 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS33515 d3d56dd37782a0b1c788f58357678193 261 PANTHER PTHR11941 3 255 1.2E-115 T 23-04-2016 DC74_RS33515 d3d56dd37782a0b1c788f58357678193 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 23-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 DC74_RS33515 d3d56dd37782a0b1c788f58357678193 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 232 5.5E-40 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS20140 94475f8b659f7252ae1bd5650beef34c 380 PANTHER PTHR23501:SF4 1 369 4.7E-97 T 23-04-2016 DC74_RS20140 94475f8b659f7252ae1bd5650beef34c 380 SUPERFAMILY SSF103473 2 374 3.01E-45 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS20140 94475f8b659f7252ae1bd5650beef34c 380 PANTHER PTHR23501 1 369 4.7E-97 T 23-04-2016 DC74_RS20140 94475f8b659f7252ae1bd5650beef34c 380 Gene3D G3DSA:1.20.1250.20 2 181 1.2E-23 T 23-04-2016 DC74_RS20140 94475f8b659f7252ae1bd5650beef34c 380 Pfam PF07690 Major Facilitator Superfamily 7 315 2.9E-29 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS20140 94475f8b659f7252ae1bd5650beef34c 380 Gene3D G3DSA:1.20.1250.20 200 371 2.4E-11 T 23-04-2016 DC74_RS01210 950c14c7a4a0849ec37491d473cf50e7 224 PANTHER PTHR11911 88 161 3.8E-26 T 23-04-2016 DC74_RS01210 950c14c7a4a0849ec37491d473cf50e7 224 PANTHER PTHR11911 7 67 3.8E-26 T 23-04-2016 DC74_RS01210 950c14c7a4a0849ec37491d473cf50e7 224 PIRSF PIRSF036990 6 223 5.7E-60 T 23-04-2016 IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON DC74_RS01210 950c14c7a4a0849ec37491d473cf50e7 224 Gene3D G3DSA:3.20.20.70 4 156 1.9E-30 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS01210 950c14c7a4a0849ec37491d473cf50e7 224 SMART SM00116 96 144 1.2E-8 T 23-04-2016 IPR000644 CBS domain DC74_RS01210 950c14c7a4a0849ec37491d473cf50e7 224 SMART SM00116 15 63 0.12 T 23-04-2016 IPR000644 CBS domain DC74_RS01210 950c14c7a4a0849ec37491d473cf50e7 224 Pfam PF04972 BON domain 146 208 1.9E-9 T 23-04-2016 IPR007055 BON domain DC74_RS01210 950c14c7a4a0849ec37491d473cf50e7 224 Pfam PF00571 CBS domain 89 143 2.5E-14 T 23-04-2016 IPR000644 CBS domain DC74_RS01210 950c14c7a4a0849ec37491d473cf50e7 224 Pfam PF00571 CBS domain 8 59 8.7E-9 T 23-04-2016 IPR000644 CBS domain DC74_RS01210 950c14c7a4a0849ec37491d473cf50e7 224 SUPERFAMILY SSF54631 5 145 6.44E-32 T 23-04-2016 DC74_RS19010 e85da8e1363f96eff8fbe299437b75e4 550 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 26 539 18.119 T 23-04-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 DC74_RS19010 e85da8e1363f96eff8fbe299437b75e4 550 PANTHER PTHR22773:SF41 23 128 1.1E-171 T 23-04-2016 DC74_RS19010 e85da8e1363f96eff8fbe299437b75e4 550 PANTHER PTHR22773:SF41 156 545 1.1E-171 T 23-04-2016 DC74_RS19010 e85da8e1363f96eff8fbe299437b75e4 550 PANTHER PTHR22773 23 128 1.1E-171 T 23-04-2016 DC74_RS19010 e85da8e1363f96eff8fbe299437b75e4 550 PANTHER PTHR22773 156 545 1.1E-171 T 23-04-2016 DC74_RS19010 e85da8e1363f96eff8fbe299437b75e4 550 Pfam PF00361 Proton-conducting membrane transporter 180 486 3.2E-73 T 23-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 DC74_RS19010 e85da8e1363f96eff8fbe299437b75e4 550 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 155 538 2.4E-115 T 23-04-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 DC74_RS18915 b817bde6209cd0ec3021e2b609b0b448 181 PANTHER PTHR10849 1 131 2.8E-73 T 23-04-2016 DC74_RS18915 b817bde6209cd0ec3021e2b609b0b448 181 Pfam PF00037 4Fe-4S binding domain 76 96 3.7E-8 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS18915 b817bde6209cd0ec3021e2b609b0b448 181 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 32 43 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS18915 b817bde6209cd0ec3021e2b609b0b448 181 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 81 92 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS18915 b817bde6209cd0ec3021e2b609b0b448 181 Gene3D G3DSA:3.30.70.20 28 114 7.6E-16 T 23-04-2016 DC74_RS18915 b817bde6209cd0ec3021e2b609b0b448 181 SUPERFAMILY SSF54862 16 124 1.13E-18 T 23-04-2016 DC74_RS18915 b817bde6209cd0ec3021e2b609b0b448 181 PANTHER PTHR10849:SF21 1 131 2.8E-73 T 23-04-2016 DC74_RS11250 056701ba5eed66516ae93f15181304a8 271 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 10 256 2.0E-57 T 23-04-2016 DC74_RS25380 610333334d8730d0e58843be80c17f0c 293 SUPERFAMILY SSF50494 33 237 3.44E-14 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS25380 610333334d8730d0e58843be80c17f0c 293 Pfam PF13365 Trypsin-like peptidase domain 72 226 3.9E-12 T 23-04-2016 DC74_RS25380 610333334d8730d0e58843be80c17f0c 293 Gene3D G3DSA:2.40.10.10 143 234 1.1E-6 T 23-04-2016 DC74_RS27345 6e14285df28af9271d4e7d18f9e77aa4 635 ProSitePatterns PS00211 ABC transporters family signature. 532 546 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS27345 6e14285df28af9271d4e7d18f9e77aa4 635 SMART SM00382 420 606 6.2E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS27345 6e14285df28af9271d4e7d18f9e77aa4 635 Pfam PF00005 ABC transporter 414 560 4.2E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS27345 6e14285df28af9271d4e7d18f9e77aa4 635 PANTHER PTHR24221 61 633 2.5E-163 T 23-04-2016 DC74_RS27345 6e14285df28af9271d4e7d18f9e77aa4 635 SUPERFAMILY SSF52540 391 629 5.03E-78 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27345 6e14285df28af9271d4e7d18f9e77aa4 635 Gene3D G3DSA:3.40.50.300 395 624 9.0E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27345 6e14285df28af9271d4e7d18f9e77aa4 635 SUPERFAMILY SSF90123 59 380 9.16E-62 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS27345 6e14285df28af9271d4e7d18f9e77aa4 635 Pfam PF00664 ABC transporter transmembrane region 71 338 4.8E-29 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 DC74_RS27345 6e14285df28af9271d4e7d18f9e77aa4 635 Gene3D G3DSA:1.20.1560.10 60 375 1.7E-71 T 23-04-2016 DC74_RS40250 4865847f8ca25618cd153e79d65f8906 396 Gene3D G3DSA:1.10.260.40 222 284 9.7E-8 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS40250 4865847f8ca25618cd153e79d65f8906 396 SMART SM00530 230 285 1.1E-4 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS40250 4865847f8ca25618cd153e79d65f8906 396 Pfam PF13560 Helix-turn-helix domain 226 286 1.0E-10 T 23-04-2016 DC74_RS40250 4865847f8ca25618cd153e79d65f8906 396 SUPERFAMILY SSF47413 225 285 7.43E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 23-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 Gene3D G3DSA:3.40.47.10 273 388 4.5E-51 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 Gene3D G3DSA:3.40.47.10 149 184 4.5E-51 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 Pfam PF02803 Thiolase, C-terminal domain 266 388 1.2E-42 T 23-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 ProSitePatterns PS00099 Thiolases active site. 370 383 - T 23-04-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 SUPERFAMILY SSF53901 267 388 2.28E-40 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 Gene3D G3DSA:3.40.47.10 6 125 1.6E-57 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 Gene3D G3DSA:3.40.47.10 185 272 1.6E-57 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 PANTHER PTHR18919 1 389 4.9E-139 T 23-04-2016 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 PIRSF PIRSF000429 1 389 1.5E-113 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 387 2.3E-116 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 SUPERFAMILY SSF53901 5 266 6.51E-61 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 Pfam PF00108 Thiolase, N-terminal domain 6 257 7.4E-51 T 23-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 DC74_RS13695 06c66fab1aece8ab38ef88c8a74ce1aa 389 PANTHER PTHR18919:SF69 1 389 4.9E-139 T 23-04-2016 DC74_RS09885 7222039ad19ca44f4e69cc3fd78af065 133 PANTHER PTHR36849 14 133 7.2E-45 T 23-04-2016 DC74_RS09885 7222039ad19ca44f4e69cc3fd78af065 133 Pfam PF04343 Protein of unknown function, DUF488 19 130 3.3E-28 T 23-04-2016 IPR007438 Protein of unknown function DUF488 DC74_RS09885 7222039ad19ca44f4e69cc3fd78af065 133 PANTHER PTHR36849:SF1 14 133 7.2E-45 T 23-04-2016 DC74_RS29235 ed4047f722a9d069fedd41779c83a19f 222 Gene3D G3DSA:3.30.70.1450 146 213 3.4E-6 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 DC74_RS29235 ed4047f722a9d069fedd41779c83a19f 222 Pfam PF02080 TrkA-C domain 151 213 1.6E-11 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 DC74_RS29235 ed4047f722a9d069fedd41779c83a19f 222 SUPERFAMILY SSF51735 1 140 2.26E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29235 ed4047f722a9d069fedd41779c83a19f 222 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.4E-9 T 23-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 DC74_RS29235 ed4047f722a9d069fedd41779c83a19f 222 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.4E-9 T 23-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 DC74_RS29235 ed4047f722a9d069fedd41779c83a19f 222 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.4E-9 T 23-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 DC74_RS29235 ed4047f722a9d069fedd41779c83a19f 222 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.4E-9 T 23-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 DC74_RS29235 ed4047f722a9d069fedd41779c83a19f 222 Pfam PF02254 TrkA-N domain 3 116 1.6E-25 T 23-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 DC74_RS29235 ed4047f722a9d069fedd41779c83a19f 222 SUPERFAMILY SSF116726 139 211 6.15E-9 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 DC74_RS29235 ed4047f722a9d069fedd41779c83a19f 222 PANTHER PTHR16254 1 158 4.3E-102 T 23-04-2016 DC74_RS29235 ed4047f722a9d069fedd41779c83a19f 222 PANTHER PTHR16254:SF23 1 158 4.3E-102 T 23-04-2016 DC74_RS29235 ed4047f722a9d069fedd41779c83a19f 222 Gene3D G3DSA:3.40.50.720 1 140 1.6E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17930 c832d51e3406b933fdcf58b0859e0c81 386 PANTHER PTHR36840:SF1 3 378 3.3E-66 T 23-04-2016 DC74_RS17930 c832d51e3406b933fdcf58b0859e0c81 386 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 18 371 5.7E-89 T 23-04-2016 IPR010640 Low temperature requirement A DC74_RS17930 c832d51e3406b933fdcf58b0859e0c81 386 PANTHER PTHR36840 3 378 3.3E-66 T 23-04-2016 DC74_RS07565 4a9c72461ffbc89599690f0d3e2a3356 205 PANTHER PTHR30055 2 203 3.8E-29 T 23-04-2016 DC74_RS07565 4a9c72461ffbc89599690f0d3e2a3356 205 SUPERFAMILY SSF46689 14 77 7.7E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS07565 4a9c72461ffbc89599690f0d3e2a3356 205 SUPERFAMILY SSF48498 88 203 6.67E-6 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS07565 4a9c72461ffbc89599690f0d3e2a3356 205 PANTHER PTHR30055:SF2 2 203 3.8E-29 T 23-04-2016 DC74_RS07565 4a9c72461ffbc89599690f0d3e2a3356 205 Gene3D G3DSA:1.10.357.10 15 204 4.5E-35 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS07565 4a9c72461ffbc89599690f0d3e2a3356 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 6.1E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS25360 77e01cf2a5606584c48832f6a3891b52 367 PANTHER PTHR10584 4 361 9.9E-102 T 23-04-2016 DC74_RS25360 77e01cf2a5606584c48832f6a3891b52 367 Pfam PF00294 pfkB family carbohydrate kinase 22 325 1.4E-51 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS25360 77e01cf2a5606584c48832f6a3891b52 367 PRINTS PR00990 Ribokinase signature 47 66 7.1E-6 T 23-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 DC74_RS25360 77e01cf2a5606584c48832f6a3891b52 367 PRINTS PR00990 Ribokinase signature 205 220 7.1E-6 T 23-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 DC74_RS25360 77e01cf2a5606584c48832f6a3891b52 367 PRINTS PR00990 Ribokinase signature 242 253 7.1E-6 T 23-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 DC74_RS25360 77e01cf2a5606584c48832f6a3891b52 367 SUPERFAMILY SSF53613 21 335 1.31E-67 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS25360 77e01cf2a5606584c48832f6a3891b52 367 Gene3D G3DSA:3.40.1190.20 21 337 7.8E-96 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS25360 77e01cf2a5606584c48832f6a3891b52 367 PANTHER PTHR10584:SF186 4 361 9.9E-102 T 23-04-2016 DC74_RS18625 d9f5061010a88e214ddc08cdadbc6246 73 Gene3D G3DSA:2.40.50.140 2 73 1.5E-39 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS18625 d9f5061010a88e214ddc08cdadbc6246 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 6.4E-38 T 23-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 DC74_RS18625 d9f5061010a88e214ddc08cdadbc6246 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.761 T 23-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 DC74_RS18625 d9f5061010a88e214ddc08cdadbc6246 73 SUPERFAMILY SSF50249 4 72 9.06E-28 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS18625 d9f5061010a88e214ddc08cdadbc6246 73 PANTHER PTHR33370 1 73 6.3E-47 T 23-04-2016 DC74_RS18625 d9f5061010a88e214ddc08cdadbc6246 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 3.4E-29 T 23-04-2016 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 DC74_RS18625 d9f5061010a88e214ddc08cdadbc6246 73 SMART SM00316 5 73 6.0E-5 T 23-04-2016 IPR022967 RNA-binding domain, S1 DC74_RS29895 9d6994556117d18536bde43052d6dced 407 Pfam PF07730 Histidine kinase 196 263 2.3E-18 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS29895 9d6994556117d18536bde43052d6dced 407 PANTHER PTHR24421 67 398 2.9E-116 T 23-04-2016 DC74_RS29895 9d6994556117d18536bde43052d6dced 407 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 304 398 5.0E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29895 9d6994556117d18536bde43052d6dced 407 PIRSF PIRSF037434 3 405 8.2E-137 T 23-04-2016 IPR017205 Signal transduction histidine kinase, ChrS DC74_RS29895 9d6994556117d18536bde43052d6dced 407 SUPERFAMILY SSF55874 270 398 2.88E-22 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29895 9d6994556117d18536bde43052d6dced 407 Gene3D G3DSA:3.30.565.10 273 399 9.4E-16 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29895 9d6994556117d18536bde43052d6dced 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 398 2.8E-8 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS29895 9d6994556117d18536bde43052d6dced 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 351 2.8E-8 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS29895 9d6994556117d18536bde43052d6dced 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 379 2.8E-8 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS29895 9d6994556117d18536bde43052d6dced 407 PANTHER PTHR24421:SF24 67 398 2.9E-116 T 23-04-2016 DC74_RS29895 9d6994556117d18536bde43052d6dced 407 SMART SM00387 301 401 2.7E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS11980 cc400bb73e671bb07997e60610bcb937 538 PANTHER PTHR10617:SF114 20 480 8.9E-54 T 23-04-2016 DC74_RS11980 cc400bb73e671bb07997e60610bcb937 538 SUPERFAMILY SSF51905 18 229 4.87E-21 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS11980 cc400bb73e671bb07997e60610bcb937 538 SUPERFAMILY SSF51905 311 373 4.87E-21 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS11980 cc400bb73e671bb07997e60610bcb937 538 PANTHER PTHR10617 20 480 8.9E-54 T 23-04-2016 DC74_RS11980 cc400bb73e671bb07997e60610bcb937 538 Gene3D G3DSA:3.50.50.60 18 199 2.9E-17 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS11980 cc400bb73e671bb07997e60610bcb937 538 Gene3D G3DSA:3.50.50.60 319 360 2.9E-17 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS11980 cc400bb73e671bb07997e60610bcb937 538 Pfam PF01494 FAD binding domain 21 192 1.8E-7 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS05810 1d72b3aa3edbcfb4f2a35f1a6bf00342 165 Gene3D G3DSA:1.10.10.10 19 151 1.0E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05810 1d72b3aa3edbcfb4f2a35f1a6bf00342 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 80 114 - T 23-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site DC74_RS05810 1d72b3aa3edbcfb4f2a35f1a6bf00342 165 Pfam PF01047 MarR family 48 105 3.1E-10 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS05810 1d72b3aa3edbcfb4f2a35f1a6bf00342 165 SMART SM00347 41 141 7.4E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS05810 1d72b3aa3edbcfb4f2a35f1a6bf00342 165 SUPERFAMILY SSF46785 22 153 3.22E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05810 1d72b3aa3edbcfb4f2a35f1a6bf00342 165 PANTHER PTHR33164 22 165 4.8E-17 T 23-04-2016 DC74_RS11000 4357b5ac7f0047a04b9222d518a2316a 218 SUPERFAMILY SSF69593 21 208 3.79E-33 T 23-04-2016 DC74_RS11000 4357b5ac7f0047a04b9222d518a2316a 218 Pfam PF01553 Acyltransferase 33 151 6.3E-18 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS11000 4357b5ac7f0047a04b9222d518a2316a 218 Gene3D G3DSA:3.40.1130.10 37 160 7.4E-15 T 23-04-2016 DC74_RS11000 4357b5ac7f0047a04b9222d518a2316a 218 PANTHER PTHR10434:SF21 23 206 6.9E-49 T 23-04-2016 DC74_RS11000 4357b5ac7f0047a04b9222d518a2316a 218 SMART SM00563 44 154 2.3E-22 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS11000 4357b5ac7f0047a04b9222d518a2316a 218 PANTHER PTHR10434 23 206 6.9E-49 T 23-04-2016 DC74_RS30975 110543eb7e38af5e61403b2e93b4c415 352 Pfam PF00248 Aldo/keto reductase family 15 308 5.8E-66 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS30975 110543eb7e38af5e61403b2e93b4c415 352 PANTHER PTHR11732 1 334 1.1E-126 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS30975 110543eb7e38af5e61403b2e93b4c415 352 PANTHER PTHR11732:SF217 1 334 1.1E-126 T 23-04-2016 DC74_RS30975 110543eb7e38af5e61403b2e93b4c415 352 Gene3D G3DSA:3.20.20.100 9 310 5.8E-89 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS30975 110543eb7e38af5e61403b2e93b4c415 352 SUPERFAMILY SSF51430 1 308 1.44E-89 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS31200 a855cb490369ab357b1cf8452a6a4527 182 PANTHER PTHR13256:SF39 12 179 4.7E-42 T 23-04-2016 DC74_RS31200 a855cb490369ab357b1cf8452a6a4527 182 SUPERFAMILY SSF55729 10 178 4.95E-43 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31200 a855cb490369ab357b1cf8452a6a4527 182 Gene3D G3DSA:3.40.630.30 10 179 9.1E-47 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31200 a855cb490369ab357b1cf8452a6a4527 182 Pfam PF13302 Acetyltransferase (GNAT) domain 17 153 2.8E-21 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS31200 a855cb490369ab357b1cf8452a6a4527 182 PANTHER PTHR13256 12 179 4.7E-42 T 23-04-2016 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 Gene3D G3DSA:1.10.630.10 1 449 3.7E-114 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 PRINTS PR00385 P450 superfamily signature 264 281 8.8E-12 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 PRINTS PR00385 P450 superfamily signature 391 400 8.8E-12 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 PRINTS PR00385 P450 superfamily signature 316 327 8.8E-12 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 PRINTS PR00385 P450 superfamily signature 400 411 8.8E-12 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 SUPERFAMILY SSF48264 1 449 2.49E-108 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 393 402 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 Pfam PF00067 Cytochrome P450 2 428 6.4E-83 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 PRINTS PR00463 E-class P450 group I signature 273 299 6.7E-21 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 PRINTS PR00463 E-class P450 group I signature 28 47 6.7E-21 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 PRINTS PR00463 E-class P450 group I signature 390 400 6.7E-21 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 PRINTS PR00463 E-class P450 group I signature 253 270 6.7E-21 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 PRINTS PR00463 E-class P450 group I signature 400 423 6.7E-21 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 PRINTS PR00463 E-class P450 group I signature 355 379 6.7E-21 T 23-04-2016 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 DC74_RS10540 e521234985e212597c6dcb8ac79f5dc0 451 PANTHER PTHR24291 1 449 4.2E-113 T 23-04-2016 DC74_RS13745 8de66a891c1b0044aedaf980b9f5e506 108 SUPERFAMILY SSF54534 2 107 2.55E-41 T 23-04-2016 DC74_RS13745 8de66a891c1b0044aedaf980b9f5e506 108 PANTHER PTHR10516 1 107 1.4E-59 T 23-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type DC74_RS13745 8de66a891c1b0044aedaf980b9f5e506 108 Gene3D G3DSA:3.10.50.40 2 107 5.0E-47 T 23-04-2016 DC74_RS13745 8de66a891c1b0044aedaf980b9f5e506 108 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 14 105 4.6E-33 T 23-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 DC74_RS11635 7dcdcefbd16792bcead1358017f76a19 207 Pfam PF04203 Sortase family 63 202 1.8E-14 T 23-04-2016 IPR005754 Sortase family DC74_RS11635 7dcdcefbd16792bcead1358017f76a19 207 PANTHER PTHR33393:SF4 50 206 1.1E-38 T 23-04-2016 DC74_RS11635 7dcdcefbd16792bcead1358017f76a19 207 SUPERFAMILY SSF63817 59 201 1.75E-11 T 23-04-2016 IPR023365 Sortase domain DC74_RS11635 7dcdcefbd16792bcead1358017f76a19 207 PANTHER PTHR33393 50 206 1.1E-38 T 23-04-2016 DC74_RS11635 7dcdcefbd16792bcead1358017f76a19 207 Gene3D G3DSA:2.40.260.10 62 184 5.0E-4 T 23-04-2016 IPR023365 Sortase domain DC74_RS04760 b2a74de51c7105164638244f57ee32c7 483 SUPERFAMILY SSF89796 225 420 5.1E-46 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS04760 b2a74de51c7105164638244f57ee32c7 483 Pfam PF02515 CoA-transferase family III 226 416 6.5E-38 T 23-04-2016 IPR003673 CoA-transferase family III GO:0003824 DC74_RS04760 b2a74de51c7105164638244f57ee32c7 483 SUPERFAMILY SSF89796 37 213 7.98E-19 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS04760 b2a74de51c7105164638244f57ee32c7 483 Gene3D G3DSA:3.40.50.10540 44 149 6.4E-4 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS04760 b2a74de51c7105164638244f57ee32c7 483 Gene3D G3DSA:3.40.50.10540 223 420 1.3E-52 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS11380 7a96becb8bd8724e63050f21b883bb11 326 Pfam PF04116 Fatty acid hydroxylase superfamily 86 218 3.4E-26 T 23-04-2016 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 DC74_RS11380 7a96becb8bd8724e63050f21b883bb11 326 PANTHER PTHR21624 5 285 1.6E-94 T 23-04-2016 DC74_RS40480 eb04d25bb5498f736d7b4ea6a11aec0c 266 PRINTS PR01217 Proline rich extensin signature 118 130 1.0E-12 T 23-04-2016 DC74_RS40480 eb04d25bb5498f736d7b4ea6a11aec0c 266 PRINTS PR01217 Proline rich extensin signature 177 198 1.0E-12 T 23-04-2016 DC74_RS40480 eb04d25bb5498f736d7b4ea6a11aec0c 266 PRINTS PR01217 Proline rich extensin signature 135 151 1.0E-12 T 23-04-2016 DC74_RS40480 eb04d25bb5498f736d7b4ea6a11aec0c 266 PRINTS PR01217 Proline rich extensin signature 158 170 1.0E-12 T 23-04-2016 DC74_RS13280 e22525d914669531219600281745be16 207 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 73 194 5.5E-11 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS13280 e22525d914669531219600281745be16 207 SUPERFAMILY SSF46689 10 66 1.13E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS13280 e22525d914669531219600281745be16 207 Gene3D G3DSA:1.10.357.10 2 201 1.2E-49 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS13280 e22525d914669531219600281745be16 207 SUPERFAMILY SSF48498 76 200 2.45E-23 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS34660 284a3b6b903b9a93558ffd28f892b0d7 331 SUPERFAMILY SSF56300 74 287 1.14E-38 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS34660 284a3b6b903b9a93558ffd28f892b0d7 331 Pfam PF00149 Calcineurin-like phosphoesterase 74 265 2.0E-9 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 DC74_RS34660 284a3b6b903b9a93558ffd28f892b0d7 331 Gene3D G3DSA:3.60.21.10 70 292 1.7E-26 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS38185 e89f35a3db9ecdd321865f61b540c644 209 Gene3D G3DSA:1.10.10.10 5 99 1.4E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38185 e89f35a3db9ecdd321865f61b540c644 209 SUPERFAMILY SSF46785 10 182 4.35E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38185 e89f35a3db9ecdd321865f61b540c644 209 Pfam PF03551 Transcriptional regulator PadR-like family 14 90 9.0E-10 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS27375 a3b99e228232702254bb257c30187e0b 179 Pfam PF13581 Histidine kinase-like ATPase domain 60 168 2.0E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27375 a3b99e228232702254bb257c30187e0b 179 SUPERFAMILY SSF55874 83 170 9.03E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27375 a3b99e228232702254bb257c30187e0b 179 Gene3D G3DSA:3.30.565.10 88 166 1.8E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17210 14f73184399f103329817a8d908f4440 393 SUPERFAMILY SSF51556 69 352 1.96E-68 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS17210 14f73184399f103329817a8d908f4440 393 TIGRFAM TIGR01224 hutI: imidazolonepropionase 33 390 1.5E-106 T 23-04-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 DC74_RS17210 14f73184399f103329817a8d908f4440 393 Pfam PF01979 Amidohydrolase family 253 368 3.1E-18 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS17210 14f73184399f103329817a8d908f4440 393 Gene3D G3DSA:2.30.40.10 32 74 7.4E-12 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS17210 14f73184399f103329817a8d908f4440 393 PANTHER PTHR22642 56 390 5.3E-103 T 23-04-2016 DC74_RS17210 14f73184399f103329817a8d908f4440 393 Hamap MF_00372 Imidazolonepropionase [hutI]. 8 393 42.679 T 23-04-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 DC74_RS17210 14f73184399f103329817a8d908f4440 393 PANTHER PTHR22642:SF1 56 390 5.3E-103 T 23-04-2016 DC74_RS17210 14f73184399f103329817a8d908f4440 393 Gene3D G3DSA:3.20.20.140 75 370 9.0E-44 T 23-04-2016 DC74_RS17210 14f73184399f103329817a8d908f4440 393 SUPERFAMILY SSF51338 353 391 1.01E-12 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS17210 14f73184399f103329817a8d908f4440 393 SUPERFAMILY SSF51338 27 70 1.01E-12 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS24675 8f98132fa094a998298fea171330d63e 159 Pfam PF13581 Histidine kinase-like ATPase domain 28 148 1.7E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS24675 8f98132fa094a998298fea171330d63e 159 Gene3D G3DSA:3.30.565.10 38 154 3.5E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS24675 8f98132fa094a998298fea171330d63e 159 SUPERFAMILY SSF55874 60 153 4.59E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS00890 95bc4b16d20e8287356efcb17235ca9f 318 PANTHER PTHR11019 62 318 3.9E-29 T 23-04-2016 DC74_RS00890 95bc4b16d20e8287356efcb17235ca9f 318 SUPERFAMILY SSF46689 261 312 6.72E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00890 95bc4b16d20e8287356efcb17235ca9f 318 PANTHER PTHR11019:SF50 62 318 3.9E-29 T 23-04-2016 DC74_RS00890 95bc4b16d20e8287356efcb17235ca9f 318 Pfam PF14525 AraC-binding-like domain 19 191 7.3E-31 T 23-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 DC74_RS00890 95bc4b16d20e8287356efcb17235ca9f 318 Gene3D G3DSA:1.10.10.60 211 262 1.7E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00890 95bc4b16d20e8287356efcb17235ca9f 318 Pfam PF12833 Helix-turn-helix domain 233 313 1.3E-18 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS00890 95bc4b16d20e8287356efcb17235ca9f 318 Gene3D G3DSA:1.10.10.60 263 315 7.9E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00890 95bc4b16d20e8287356efcb17235ca9f 318 SMART SM00342 227 312 5.5E-21 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS06100 efda05f63f3cd1c10bb9a826570806c3 281 PANTHER PTHR23200 13 277 1.5E-85 T 23-04-2016 DC74_RS06100 efda05f63f3cd1c10bb9a826570806c3 281 PANTHER PTHR23200:SF38 13 277 1.5E-85 T 23-04-2016 DC74_RS06100 efda05f63f3cd1c10bb9a826570806c3 281 Pfam PF00753 Metallo-beta-lactamase superfamily 32 219 1.1E-19 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS06100 efda05f63f3cd1c10bb9a826570806c3 281 SMART SM00849 32 264 6.0E-14 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS06100 efda05f63f3cd1c10bb9a826570806c3 281 SUPERFAMILY SSF56281 1 264 1.83E-28 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS06100 efda05f63f3cd1c10bb9a826570806c3 281 Gene3D G3DSA:3.60.15.10 1 265 1.7E-34 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS22230 0cd6d4642f2b546afd885db1a17f0953 430 PANTHER PTHR37312 78 430 7.7E-68 T 23-04-2016 DC74_RS22230 0cd6d4642f2b546afd885db1a17f0953 430 Pfam PF01757 Acyltransferase family 95 397 5.0E-20 T 23-04-2016 IPR002656 Acyltransferase 3 GO:0016747 DC74_RS38610 5ef9f5b19c90710cf55144b7b8da3e23 409 SUPERFAMILY SSF51905 8 228 8.42E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38610 5ef9f5b19c90710cf55144b7b8da3e23 409 SUPERFAMILY SSF51905 330 387 8.42E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38610 5ef9f5b19c90710cf55144b7b8da3e23 409 Gene3D G3DSA:3.50.50.60 9 84 7.8E-48 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38610 5ef9f5b19c90710cf55144b7b8da3e23 409 Gene3D G3DSA:3.50.50.60 330 386 7.8E-48 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38610 5ef9f5b19c90710cf55144b7b8da3e23 409 Gene3D G3DSA:3.50.50.60 149 227 7.8E-48 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38610 5ef9f5b19c90710cf55144b7b8da3e23 409 SUPERFAMILY SSF54373 228 330 1.07E-9 T 23-04-2016 DC74_RS38610 5ef9f5b19c90710cf55144b7b8da3e23 409 Pfam PF01266 FAD dependent oxidoreductase 9 368 2.2E-57 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DC74_RS38610 5ef9f5b19c90710cf55144b7b8da3e23 409 PANTHER PTHR13847 10 386 3.7E-76 T 23-04-2016 DC74_RS38610 5ef9f5b19c90710cf55144b7b8da3e23 409 Gene3D G3DSA:3.30.9.10 228 328 4.7E-10 T 23-04-2016 DC74_RS38610 5ef9f5b19c90710cf55144b7b8da3e23 409 Gene3D G3DSA:3.30.9.10 96 148 4.7E-10 T 23-04-2016 DC74_RS38610 5ef9f5b19c90710cf55144b7b8da3e23 409 PANTHER PTHR13847:SF189 10 386 3.7E-76 T 23-04-2016 DC74_RS22155 5ed0a8d665b1fe91bcd64e2bed865384 113 Pfam PF01740 STAS domain 12 108 2.5E-17 T 23-04-2016 IPR002645 STAS domain DC74_RS22155 5ed0a8d665b1fe91bcd64e2bed865384 113 PANTHER PTHR33495:SF2 2 111 1.5E-41 T 23-04-2016 DC74_RS22155 5ed0a8d665b1fe91bcd64e2bed865384 113 PANTHER PTHR33495 2 111 1.5E-41 T 23-04-2016 DC74_RS22155 5ed0a8d665b1fe91bcd64e2bed865384 113 SUPERFAMILY SSF52091 3 110 4.12E-31 T 23-04-2016 IPR002645 STAS domain DC74_RS22155 5ed0a8d665b1fe91bcd64e2bed865384 113 Gene3D G3DSA:3.30.750.24 4 111 3.4E-40 T 23-04-2016 IPR002645 STAS domain DC74_RS22155 5ed0a8d665b1fe91bcd64e2bed865384 113 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 107 7.9E-33 T 23-04-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 DC74_RS18165 614aabacab98f1d21d22ef5c84af7b09 274 PANTHER PTHR30011 24 239 2.5E-82 T 23-04-2016 DC74_RS18165 614aabacab98f1d21d22ef5c84af7b09 274 Gene3D G3DSA:3.20.20.30 17 229 6.5E-58 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS18165 614aabacab98f1d21d22ef5c84af7b09 274 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 254 1.5E-66 T 23-04-2016 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted DC74_RS18165 614aabacab98f1d21d22ef5c84af7b09 274 SUPERFAMILY SSF51679 17 273 9.13E-55 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS18165 614aabacab98f1d21d22ef5c84af7b09 274 PANTHER PTHR30011:SF25 24 239 2.5E-82 T 23-04-2016 DC74_RS18165 614aabacab98f1d21d22ef5c84af7b09 274 Pfam PF00296 Luciferase-like monooxygenase 18 230 3.0E-46 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS38635 ffc70e6646104e8cf4eff58f72ec9327 126 Pfam PF03995 Peptidase inhibitor family I36 34 106 2.4E-22 T 23-04-2016 DC74_RS14060 6d8b56519c6b0bb5f30120a4bdb8e3c6 312 SUPERFAMILY SSF52266 229 297 2.33E-25 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS14060 6d8b56519c6b0bb5f30120a4bdb8e3c6 312 SUPERFAMILY SSF52266 61 200 2.33E-25 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS14060 6d8b56519c6b0bb5f30120a4bdb8e3c6 312 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 67 287 4.3E-20 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS14060 6d8b56519c6b0bb5f30120a4bdb8e3c6 312 Gene3D G3DSA:3.40.50.1110 62 199 1.7E-24 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS14060 6d8b56519c6b0bb5f30120a4bdb8e3c6 312 Gene3D G3DSA:3.40.50.1110 235 300 1.7E-24 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS16335 b7e6e31d0548186db7a9c88a8e8f1e78 211 Pfam PF01725 Ham1 family 15 203 6.0E-53 T 23-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 DC74_RS16335 b7e6e31d0548186db7a9c88a8e8f1e78 211 Gene3D G3DSA:3.90.950.10 10 209 1.8E-79 T 23-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like DC74_RS16335 b7e6e31d0548186db7a9c88a8e8f1e78 211 PANTHER PTHR11067:SF9 8 209 6.4E-71 T 23-04-2016 DC74_RS16335 b7e6e31d0548186db7a9c88a8e8f1e78 211 PANTHER PTHR11067 8 209 6.4E-71 T 23-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 DC74_RS16335 b7e6e31d0548186db7a9c88a8e8f1e78 211 SUPERFAMILY SSF52972 12 207 4.45E-65 T 23-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like DC74_RS16335 b7e6e31d0548186db7a9c88a8e8f1e78 211 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 15 203 2.7E-51 T 23-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 DC74_RS16335 b7e6e31d0548186db7a9c88a8e8f1e78 211 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 13 208 47.024 T 23-04-2016 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 DC74_RS14850 25c1449c848ad1e67bf2753d46b9915f 266 Pfam PF00005 ABC transporter 32 179 7.3E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS14850 25c1449c848ad1e67bf2753d46b9915f 266 Gene3D G3DSA:3.40.50.300 10 240 1.7E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14850 25c1449c848ad1e67bf2753d46b9915f 266 SUPERFAMILY SSF52540 16 241 2.51E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS14850 25c1449c848ad1e67bf2753d46b9915f 266 SMART SM00382 41 235 6.6E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS14850 25c1449c848ad1e67bf2753d46b9915f 266 PANTHER PTHR24220 18 236 6.0E-67 T 23-04-2016 DC74_RS03825 e3ca1ef48928c38132e7ef70166654ad 150 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 130 7.1E-25 T 23-04-2016 IPR000944 Transcription regulator Rrf2-type DC74_RS03825 e3ca1ef48928c38132e7ef70166654ad 150 Gene3D G3DSA:1.10.10.10 2 131 2.4E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS03825 e3ca1ef48928c38132e7ef70166654ad 150 PANTHER PTHR33221:SF4 2 131 8.4E-55 T 23-04-2016 DC74_RS03825 e3ca1ef48928c38132e7ef70166654ad 150 PANTHER PTHR33221 2 131 8.4E-55 T 23-04-2016 DC74_RS03825 e3ca1ef48928c38132e7ef70166654ad 150 Pfam PF02082 Transcriptional regulator 2 82 7.5E-16 T 23-04-2016 IPR000944 Transcription regulator Rrf2-type DC74_RS03825 e3ca1ef48928c38132e7ef70166654ad 150 SUPERFAMILY SSF46785 2 131 9.48E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS39325 bc3b44c1aa76e62a68433b6cf36a8975 159 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 11 113 3.1E-16 T 23-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 DC74_RS39325 bc3b44c1aa76e62a68433b6cf36a8975 159 Gene3D G3DSA:3.40.140.10 9 144 3.2E-22 T 23-04-2016 DC74_RS39325 bc3b44c1aa76e62a68433b6cf36a8975 159 SUPERFAMILY SSF53927 12 141 7.86E-28 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS31205 bfda7549102ca3ca1d2f4690d143868f 314 Pfam PF03466 LysR substrate binding domain 93 303 1.5E-27 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS31205 bfda7549102ca3ca1d2f4690d143868f 314 SUPERFAMILY SSF46785 2 83 7.07E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31205 bfda7549102ca3ca1d2f4690d143868f 314 SUPERFAMILY SSF53850 96 304 1.47E-26 T 23-04-2016 DC74_RS31205 bfda7549102ca3ca1d2f4690d143868f 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.3E-14 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS31205 bfda7549102ca3ca1d2f4690d143868f 314 PANTHER PTHR30346 1 304 5.4E-51 T 23-04-2016 DC74_RS31205 bfda7549102ca3ca1d2f4690d143868f 314 Gene3D G3DSA:1.10.10.10 2 83 8.5E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31205 bfda7549102ca3ca1d2f4690d143868f 314 Gene3D G3DSA:3.40.190.10 98 182 4.2E-12 T 23-04-2016 DC74_RS31205 bfda7549102ca3ca1d2f4690d143868f 314 Gene3D G3DSA:3.40.190.10 183 277 1.2E-17 T 23-04-2016 DC74_RS22930 1872ac3091629ea5ad9944207c0e3788 138 Pfam PF02583 Metal-sensitive transcriptional repressor 53 133 1.3E-29 T 23-04-2016 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 DC74_RS22930 1872ac3091629ea5ad9944207c0e3788 138 PANTHER PTHR33677 47 137 8.0E-32 T 23-04-2016 DC74_RS22930 1872ac3091629ea5ad9944207c0e3788 138 PANTHER PTHR33677:SF3 47 137 8.0E-32 T 23-04-2016 DC74_RS22300 0f0b48bb88139d42c092df5342ca2951 281 Gene3D G3DSA:3.60.110.10 2 267 6.1E-62 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS22300 0f0b48bb88139d42c092df5342ca2951 281 Pfam PF00795 Carbon-nitrogen hydrolase 2 253 1.1E-30 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS22300 0f0b48bb88139d42c092df5342ca2951 281 SUPERFAMILY SSF56317 1 267 1.96E-59 T 23-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 DC74_RS22300 0f0b48bb88139d42c092df5342ca2951 281 PANTHER PTHR23088 1 273 1.8E-51 T 23-04-2016 DC74_RS16750 5c8bfb533c2efe56e35dddc582b25e18 559 Pfam PF00535 Glycosyl transferase family 2 20 140 2.4E-27 T 23-04-2016 IPR001173 Glycosyltransferase 2-like DC74_RS16750 5c8bfb533c2efe56e35dddc582b25e18 559 PANTHER PTHR22916:SF3 15 311 1.2E-40 T 23-04-2016 DC74_RS16750 5c8bfb533c2efe56e35dddc582b25e18 559 Gene3D G3DSA:3.90.550.10 18 256 2.3E-37 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS16750 5c8bfb533c2efe56e35dddc582b25e18 559 PANTHER PTHR22916 15 311 1.2E-40 T 23-04-2016 DC74_RS16750 5c8bfb533c2efe56e35dddc582b25e18 559 SUPERFAMILY SSF53448 12 259 5.42E-41 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS06045 e183cffd54dfacfd718b8233a7bb47ce 245 Gene3D G3DSA:3.90.1680.10 1 243 4.4E-74 T 23-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS06045 e183cffd54dfacfd718b8233a7bb47ce 245 Pfam PF02586 SOS response associated peptidase (SRAP) 1 233 1.7E-67 T 23-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS06045 e183cffd54dfacfd718b8233a7bb47ce 245 PANTHER PTHR13604 2 243 2.6E-74 T 23-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS06045 e183cffd54dfacfd718b8233a7bb47ce 245 SUPERFAMILY SSF143081 2 243 5.36E-69 T 23-04-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 Gene3D G3DSA:3.40.50.1820 58 144 7.8E-59 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 Gene3D G3DSA:3.40.50.1820 361 479 7.8E-59 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 Gene3D G3DSA:3.40.50.1820 188 311 7.8E-59 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 Pfam PF00561 alpha/beta hydrolase fold 95 456 3.3E-26 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 PANTHER PTHR10992 367 481 1.1E-40 T 23-04-2016 DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 PANTHER PTHR10992 187 276 1.1E-40 T 23-04-2016 DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 PANTHER PTHR10992 53 143 1.1E-40 T 23-04-2016 DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 PANTHER PTHR10992:SF878 367 481 1.1E-40 T 23-04-2016 DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 PANTHER PTHR10992:SF878 187 276 1.1E-40 T 23-04-2016 DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 PANTHER PTHR10992:SF878 53 143 1.1E-40 T 23-04-2016 DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 SUPERFAMILY SSF53474 179 344 6.72E-29 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 SUPERFAMILY SSF53474 414 464 6.72E-29 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05275 40e8ca0a11795ff632059142b77fbc16 504 SUPERFAMILY SSF53474 84 139 6.72E-29 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS22345 af6918d2c04aba02cb5c7008cb6f3db7 160 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 27 157 4.1E-22 T 23-04-2016 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 DC74_RS22345 af6918d2c04aba02cb5c7008cb6f3db7 160 SUPERFAMILY SSF55961 15 158 3.67E-34 T 23-04-2016 DC74_RS22345 af6918d2c04aba02cb5c7008cb6f3db7 160 Gene3D G3DSA:3.30.530.20 14 158 1.2E-35 T 23-04-2016 IPR023393 START-like domain DC74_RS05770 e457b91252649940a5f8c6e70610a980 292 PANTHER PTHR33745 77 288 3.1E-57 T 23-04-2016 DC74_RS05770 e457b91252649940a5f8c6e70610a980 292 Gene3D G3DSA:3.30.750.24 166 258 1.4E-14 T 23-04-2016 IPR002645 STAS domain DC74_RS05770 e457b91252649940a5f8c6e70610a980 292 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 14 112 1.3E-15 T 23-04-2016 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain DC74_RS05770 e457b91252649940a5f8c6e70610a980 292 PANTHER PTHR33745:SF1 77 288 3.1E-57 T 23-04-2016 DC74_RS05770 e457b91252649940a5f8c6e70610a980 292 Pfam PF01740 STAS domain 174 271 1.2E-9 T 23-04-2016 IPR002645 STAS domain DC74_RS05770 e457b91252649940a5f8c6e70610a980 292 SUPERFAMILY SSF52091 165 275 2.75E-18 T 23-04-2016 IPR002645 STAS domain DC74_RS20515 810798d8bf476dd7c8892aede854a56e 144 SMART SM00347 26 126 6.5E-14 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS20515 810798d8bf476dd7c8892aede854a56e 144 Gene3D G3DSA:1.10.10.10 11 139 6.4E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20515 810798d8bf476dd7c8892aede854a56e 144 PANTHER PTHR33164 15 143 3.8E-17 T 23-04-2016 DC74_RS20515 810798d8bf476dd7c8892aede854a56e 144 SUPERFAMILY SSF46785 16 139 8.24E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20515 810798d8bf476dd7c8892aede854a56e 144 Pfam PF01047 MarR family 33 89 1.7E-14 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS39310 6acd97831bf08a1e8bc45095eafcb7f7 233 Gene3D G3DSA:3.40.50.1820 3 232 3.7E-39 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS39310 6acd97831bf08a1e8bc45095eafcb7f7 233 PANTHER PTHR10992 3 111 1.1E-23 T 23-04-2016 DC74_RS39310 6acd97831bf08a1e8bc45095eafcb7f7 233 Pfam PF12697 Alpha/beta hydrolase family 4 227 3.0E-13 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS39310 6acd97831bf08a1e8bc45095eafcb7f7 233 PANTHER PTHR10992:SF810 3 111 1.1E-23 T 23-04-2016 DC74_RS39310 6acd97831bf08a1e8bc45095eafcb7f7 233 SUPERFAMILY SSF53474 3 231 1.12E-25 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS12065 2f1ef0c17d0a0953dd7b6e0ef1c4e305 619 SUPERFAMILY SSF53955 93 267 7.03E-31 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS12065 2f1ef0c17d0a0953dd7b6e0ef1c4e305 619 Gene3D G3DSA:1.10.530.10 111 145 1.3E-8 T 23-04-2016 DC74_RS12065 2f1ef0c17d0a0953dd7b6e0ef1c4e305 619 Gene3D G3DSA:1.10.530.10 181 265 1.3E-8 T 23-04-2016 DC74_RS12065 2f1ef0c17d0a0953dd7b6e0ef1c4e305 619 Gene3D G3DSA:2.60.40.920 394 471 2.2E-6 T 23-04-2016 IPR003344 Big-1 (bacterial Ig-like domain 1) domain DC74_RS02685 15db0eb9725bccd6fe9f0b6cdc9d88d6 452 Gene3D G3DSA:1.20.1250.20 28 230 1.3E-20 T 23-04-2016 DC74_RS02685 15db0eb9725bccd6fe9f0b6cdc9d88d6 452 Gene3D G3DSA:1.20.1250.20 252 437 5.2E-18 T 23-04-2016 DC74_RS02685 15db0eb9725bccd6fe9f0b6cdc9d88d6 452 ProSitePatterns PS00217 Sugar transport proteins signature 2. 140 165 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS02685 15db0eb9725bccd6fe9f0b6cdc9d88d6 452 SUPERFAMILY SSF103473 26 436 1.7E-56 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS02685 15db0eb9725bccd6fe9f0b6cdc9d88d6 452 PANTHER PTHR23508:SF4 29 426 1.8E-81 T 23-04-2016 DC74_RS02685 15db0eb9725bccd6fe9f0b6cdc9d88d6 452 PANTHER PTHR23508 29 426 1.8E-81 T 23-04-2016 DC74_RS02685 15db0eb9725bccd6fe9f0b6cdc9d88d6 452 Pfam PF07690 Major Facilitator Superfamily 36 355 3.8E-24 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS02970 5408e5ede221278ae3c73602107534d9 190 Gene3D G3DSA:1.10.1740.10 13 119 3.6E-12 T 23-04-2016 DC74_RS02970 5408e5ede221278ae3c73602107534d9 190 Gene3D G3DSA:1.10.10.10 137 174 1.9E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02970 5408e5ede221278ae3c73602107534d9 190 SUPERFAMILY SSF88946 18 109 5.1E-12 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS02970 5408e5ede221278ae3c73602107534d9 190 PANTHER PTHR30173 1 174 6.2E-16 T 23-04-2016 DC74_RS02970 5408e5ede221278ae3c73602107534d9 190 Pfam PF04542 Sigma-70 region 2 32 97 3.1E-9 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS02970 5408e5ede221278ae3c73602107534d9 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 28 179 6.6E-16 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS07645 ddee03bde97e7512b84553748751c882 191 Pfam PF07336 Putative stress-induced transcription regulator 14 135 1.5E-19 T 23-04-2016 IPR010852 Putative stress-induced transcription regulator DC74_RS07645 ddee03bde97e7512b84553748751c882 191 Gene3D G3DSA:1.10.3300.10 7 184 3.1E-41 T 23-04-2016 IPR023286 ABATE domain DC74_RS07645 ddee03bde97e7512b84553748751c882 191 Pfam PF11706 CGNR zinc finger 141 181 1.3E-15 T 23-04-2016 IPR021005 Zinc finger, CGNR DC74_RS07645 ddee03bde97e7512b84553748751c882 191 SUPERFAMILY SSF160904 7 181 2.09E-40 T 23-04-2016 DC74_RS07645 ddee03bde97e7512b84553748751c882 191 PANTHER PTHR35525 18 190 1.1E-22 T 23-04-2016 DC74_RS04085 e0ae82affab02983614db6f3234b23af 167 PANTHER PTHR11124 2 159 1.6E-32 T 23-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 DC74_RS04085 e0ae82affab02983614db6f3234b23af 167 SUPERFAMILY SSF56300 2 164 1.52E-35 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS04085 e0ae82affab02983614db6f3234b23af 167 Gene3D G3DSA:3.60.21.10 2 156 9.9E-33 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS04085 e0ae82affab02983614db6f3234b23af 167 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 152 3.5E-25 T 23-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 DC74_RS04085 e0ae82affab02983614db6f3234b23af 167 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 151 1.6E-25 T 23-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type DC74_RS03295 8397b0109539e3cb88b0c12711f3f5a1 183 Pfam PF13358 DDE superfamily endonuclease 2 147 8.8E-25 T 23-04-2016 DC74_RS03295 8397b0109539e3cb88b0c12711f3f5a1 183 Gene3D G3DSA:3.30.420.10 60 162 2.7E-5 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS03905 7189a0a2e2f92b793b256c281df5fba8 157 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 30 80 5.1E-22 T 23-04-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS03905 7189a0a2e2f92b793b256c281df5fba8 157 Gene3D G3DSA:1.20.1290.10 14 150 1.6E-46 T 23-04-2016 IPR029032 AhpD-like DC74_RS03905 7189a0a2e2f92b793b256c281df5fba8 157 SUPERFAMILY SSF69118 14 148 9.87E-41 T 23-04-2016 IPR029032 AhpD-like DC74_RS03905 7189a0a2e2f92b793b256c281df5fba8 157 Pfam PF02627 Carboxymuconolactone decarboxylase family 11 96 2.1E-22 T 23-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS22040 ee29a15b465e3412b8784cec9cfd80d9 276 SMART SM00849 39 204 5.3E-27 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS22040 ee29a15b465e3412b8784cec9cfd80d9 276 PANTHER PTHR23131 27 276 6.4E-79 T 23-04-2016 DC74_RS22040 ee29a15b465e3412b8784cec9cfd80d9 276 SUPERFAMILY SSF56281 24 275 6.3E-50 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS22040 ee29a15b465e3412b8784cec9cfd80d9 276 Gene3D G3DSA:3.60.15.10 22 234 4.1E-49 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS22040 ee29a15b465e3412b8784cec9cfd80d9 276 Pfam PF00753 Metallo-beta-lactamase superfamily 36 204 4.6E-16 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS22040 ee29a15b465e3412b8784cec9cfd80d9 276 PANTHER PTHR23131:SF4 27 276 6.4E-79 T 23-04-2016 DC74_RS27030 fcbc47e28bdbdc4789b10859f30daebe 465 Pfam PF01554 MatE 249 409 4.2E-28 T 23-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 DC74_RS27030 fcbc47e28bdbdc4789b10859f30daebe 465 Pfam PF01554 MatE 24 183 2.2E-34 T 23-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 DC74_RS27030 fcbc47e28bdbdc4789b10859f30daebe 465 PIRSF PIRSF006603 1 445 7.6E-87 T 23-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 DC74_RS27030 fcbc47e28bdbdc4789b10859f30daebe 465 TIGRFAM TIGR00797 matE: MATE efflux family protein 24 410 5.2E-68 T 23-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 DC74_RS27030 fcbc47e28bdbdc4789b10859f30daebe 465 PANTHER PTHR11206 16 421 8.9E-70 T 23-04-2016 DC74_RS27030 fcbc47e28bdbdc4789b10859f30daebe 465 PANTHER PTHR11206:SF95 16 421 8.9E-70 T 23-04-2016 DC74_RS05865 635d080591d1ec305ef0780e6f238459 103 SUPERFAMILY SSF51182 11 102 1.09E-15 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS05865 635d080591d1ec305ef0780e6f238459 103 Pfam PF07883 Cupin domain 37 95 1.3E-10 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS05865 635d080591d1ec305ef0780e6f238459 103 Gene3D G3DSA:2.60.120.10 1 102 5.8E-18 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS37915 cb56ff85f11b57a8d97e586a66ebe1c0 111 PANTHER PTHR14194:SF59 1 103 1.2E-21 T 23-04-2016 DC74_RS37915 cb56ff85f11b57a8d97e586a66ebe1c0 111 PANTHER PTHR14194 1 103 1.2E-21 T 23-04-2016 DC74_RS37915 cb56ff85f11b57a8d97e586a66ebe1c0 111 SUPERFAMILY SSF51735 2 101 1.34E-9 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS28100 d03c5a27d005e3d94f7cedc287650af9 286 Pfam PF13649 Methyltransferase domain 63 137 6.1E-7 T 23-04-2016 DC74_RS28100 d03c5a27d005e3d94f7cedc287650af9 286 SUPERFAMILY SSF53335 35 215 9.82E-19 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS28100 d03c5a27d005e3d94f7cedc287650af9 286 Gene3D G3DSA:3.40.50.150 37 214 4.3E-16 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS39945 a1d44fbc38b4502bb6737f1d1a5f88bc 332 Gene3D G3DSA:3.30.460.10 124 155 2.1E-4 T 23-04-2016 DC74_RS35225 945fdabdb2d865cbf2256b25b599d419 164 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 68 156 1.7E-7 T 23-04-2016 DC74_RS35225 945fdabdb2d865cbf2256b25b599d419 164 Gene3D G3DSA:2.60.120.200 72 157 1.3E-8 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS35225 945fdabdb2d865cbf2256b25b599d419 164 SUPERFAMILY SSF49899 88 157 4.59E-5 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS05355 c8c366eb63fea1765162b95281ba0851 469 Pfam PF07690 Major Facilitator Superfamily 268 455 1.9E-9 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS05355 c8c366eb63fea1765162b95281ba0851 469 PANTHER PTHR23508:SF1 32 468 3.3E-150 T 23-04-2016 DC74_RS05355 c8c366eb63fea1765162b95281ba0851 469 PANTHER PTHR23508 32 468 3.3E-150 T 23-04-2016 DC74_RS05355 c8c366eb63fea1765162b95281ba0851 469 SUPERFAMILY SSF103473 20 454 4.97E-63 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS05355 c8c366eb63fea1765162b95281ba0851 469 Gene3D G3DSA:1.20.1250.20 263 451 1.2E-17 T 23-04-2016 DC74_RS05355 c8c366eb63fea1765162b95281ba0851 469 Gene3D G3DSA:1.20.1250.20 51 243 3.4E-23 T 23-04-2016 DC74_RS05355 c8c366eb63fea1765162b95281ba0851 469 Pfam PF00083 Sugar (and other) transporter 39 249 3.1E-22 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS09145 1a573f545d63f924d2dc99d34cedb664 717 Gene3D G3DSA:1.20.910.10 523 567 1.2E-5 T 23-04-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 DC74_RS09145 1a573f545d63f924d2dc99d34cedb664 717 SMART SM01236 523 632 2.6E-29 T 23-04-2016 DC74_RS09145 1a573f545d63f924d2dc99d34cedb664 717 Pfam PF14518 Iron-containing redox enzyme 494 674 5.0E-20 T 23-04-2016 IPR028201 PqqC-like protein DC74_RS28690 386a753d0f300ad1d831df1ef7efa12e 156 Pfam PF00210 Ferritin-like domain 18 154 4.5E-22 T 23-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 DC74_RS28690 386a753d0f300ad1d831df1ef7efa12e 156 SUPERFAMILY SSF47240 3 153 7.67E-48 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS28690 386a753d0f300ad1d831df1ef7efa12e 156 PIRSF PIRSF005900 1 156 1.5E-43 T 23-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 DC74_RS28690 386a753d0f300ad1d831df1ef7efa12e 156 ProSitePatterns PS00818 Dps protein family signature 1. 38 54 - T 23-04-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 DC74_RS28690 386a753d0f300ad1d831df1ef7efa12e 156 PANTHER PTHR30295:SF10 1 153 2.5E-55 T 23-04-2016 DC74_RS28690 386a753d0f300ad1d831df1ef7efa12e 156 PANTHER PTHR30295 1 153 2.5E-55 T 23-04-2016 DC74_RS28690 386a753d0f300ad1d831df1ef7efa12e 156 Gene3D G3DSA:1.20.1260.10 3 154 9.1E-48 T 23-04-2016 IPR012347 Ferritin-related DC74_RS28690 386a753d0f300ad1d831df1ef7efa12e 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 62 78 6.9E-12 T 23-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 DC74_RS28690 386a753d0f300ad1d831df1ef7efa12e 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 133 151 6.9E-12 T 23-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 DC74_RS28690 386a753d0f300ad1d831df1ef7efa12e 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 38 54 6.9E-12 T 23-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 DC74_RS19920 2cbb2c192856e4a1856720e816de9430 178 Pfam PF10722 Putative bacterial sensory transduction regulator 30 155 1.0E-15 T 23-04-2016 IPR019660 Putative sensory transduction regulator YbjN DC74_RS25710 ae242b987860a30de39043725aad0617 1058 PANTHER PTHR10799 448 600 1.5E-35 T 23-04-2016 DC74_RS25710 ae242b987860a30de39043725aad0617 1058 PANTHER PTHR10799 135 426 1.5E-35 T 23-04-2016 DC74_RS25710 ae242b987860a30de39043725aad0617 1058 Pfam PF00271 Helicase conserved C-terminal domain 477 583 5.2E-9 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS25710 ae242b987860a30de39043725aad0617 1058 Gene3D G3DSA:3.40.50.300 119 283 3.7E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25710 ae242b987860a30de39043725aad0617 1058 PANTHER PTHR10799:SF576 448 600 1.5E-35 T 23-04-2016 DC74_RS25710 ae242b987860a30de39043725aad0617 1058 PANTHER PTHR10799:SF576 135 426 1.5E-35 T 23-04-2016 DC74_RS25710 ae242b987860a30de39043725aad0617 1058 SMART SM00487 112 313 8.0E-11 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS25710 ae242b987860a30de39043725aad0617 1058 Gene3D G3DSA:3.40.50.300 455 585 4.5E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25710 ae242b987860a30de39043725aad0617 1058 Pfam PF00176 SNF2 family N-terminal domain 137 298 1.0E-8 T 23-04-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 DC74_RS25710 ae242b987860a30de39043725aad0617 1058 SUPERFAMILY SSF52540 239 300 7.7E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25710 ae242b987860a30de39043725aad0617 1058 SUPERFAMILY SSF52540 447 606 7.7E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25710 ae242b987860a30de39043725aad0617 1058 SMART SM00490 490 583 0.0025 T 23-04-2016 IPR001650 Helicase, C-terminal DC74_RS25710 ae242b987860a30de39043725aad0617 1058 SUPERFAMILY SSF52540 80 316 8.55E-28 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05690 3c7095474f6d8e76999c8da277f8869e 261 PANTHER PTHR11614 1 254 1.0E-54 T 23-04-2016 DC74_RS05690 3c7095474f6d8e76999c8da277f8869e 261 PANTHER PTHR11614:SF108 1 254 1.0E-54 T 23-04-2016 DC74_RS05690 3c7095474f6d8e76999c8da277f8869e 261 Gene3D G3DSA:3.40.50.1820 179 250 1.2E-32 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05690 3c7095474f6d8e76999c8da277f8869e 261 Gene3D G3DSA:3.40.50.1820 2 135 1.2E-32 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05690 3c7095474f6d8e76999c8da277f8869e 261 SUPERFAMILY SSF53474 181 251 9.2E-35 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05690 3c7095474f6d8e76999c8da277f8869e 261 SUPERFAMILY SSF53474 2 137 9.2E-35 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05690 3c7095474f6d8e76999c8da277f8869e 261 Pfam PF12146 Serine aminopeptidase, S33 31 151 2.5E-10 T 23-04-2016 IPR022742 Serine aminopeptidase, S33 DC74_RS27625 007b38ae500336aea1a2cd0e96c65aac 274 PANTHER PTHR10245:SF7 16 272 1.1E-41 T 23-04-2016 DC74_RS27625 007b38ae500336aea1a2cd0e96c65aac 274 Pfam PF13560 Helix-turn-helix domain 16 73 1.4E-11 T 23-04-2016 DC74_RS27625 007b38ae500336aea1a2cd0e96c65aac 274 PANTHER PTHR10245 16 272 1.1E-41 T 23-04-2016 DC74_RS27625 007b38ae500336aea1a2cd0e96c65aac 274 SUPERFAMILY SSF47413 10 86 7.93E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS27625 007b38ae500336aea1a2cd0e96c65aac 274 Gene3D G3DSA:1.10.260.40 15 70 1.9E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS27625 007b38ae500336aea1a2cd0e96c65aac 274 SMART SM00530 19 74 9.4E-7 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS33730 d1f5f9b2d0fd6efd7670eae817f3f663 214 Pfam PF01638 HxlR-like helix-turn-helix 19 104 8.6E-22 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS33730 d1f5f9b2d0fd6efd7670eae817f3f663 214 SUPERFAMILY SSF46785 6 111 2.85E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS33730 d1f5f9b2d0fd6efd7670eae817f3f663 214 Gene3D G3DSA:1.10.10.10 4 106 1.4E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS33730 d1f5f9b2d0fd6efd7670eae817f3f663 214 PANTHER PTHR33204:SF9 1 157 6.3E-52 T 23-04-2016 DC74_RS33730 d1f5f9b2d0fd6efd7670eae817f3f663 214 PANTHER PTHR33204 1 157 6.3E-52 T 23-04-2016 DC74_RS11160 b1862e3aef6330744d3563ef8f3d1685 421 PIRSF PIRSF033563 6 418 3.1E-100 T 23-04-2016 IPR008323 Uncharacterised conserved protein UCP033563 DC74_RS11160 b1862e3aef6330744d3563ef8f3d1685 421 Pfam PF06245 Protein of unknown function (DUF1015) 9 414 1.2E-107 T 23-04-2016 IPR008323 Uncharacterised conserved protein UCP033563 DC74_RS11160 b1862e3aef6330744d3563ef8f3d1685 421 PANTHER PTHR36454:SF1 3 419 1.6E-117 T 23-04-2016 DC74_RS11160 b1862e3aef6330744d3563ef8f3d1685 421 PANTHER PTHR36454 3 419 1.6E-117 T 23-04-2016 DC74_RS35835 a70fdd759bceb612f4a02ecfacc92ff6 232 Pfam PF14016 Protein of unknown function (DUF4232) 100 226 6.4E-31 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS26205 feec9b5f4dac0bee36ebfdf4393cdf6a 116 PANTHER PTHR38839:SF2 12 116 5.6E-56 T 23-04-2016 DC74_RS26205 feec9b5f4dac0bee36ebfdf4393cdf6a 116 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 15 107 14.152 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS26205 feec9b5f4dac0bee36ebfdf4393cdf6a 116 PANTHER PTHR38839 12 116 5.6E-56 T 23-04-2016 DC74_RS26205 feec9b5f4dac0bee36ebfdf4393cdf6a 116 Pfam PF02467 Transcription factor WhiB 42 91 1.0E-15 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS17565 73c43c21de2b5c00299d66da5c79269a 555 PANTHER PTHR11819:SF7 13 534 1.5E-170 T 23-04-2016 DC74_RS17565 73c43c21de2b5c00299d66da5c79269a 555 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 44 452 1.0E-66 T 23-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS17565 73c43c21de2b5c00299d66da5c79269a 555 Pfam PF00474 Sodium:solute symporter family 44 452 8.4E-47 T 23-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS17565 73c43c21de2b5c00299d66da5c79269a 555 PANTHER PTHR11819 13 534 1.5E-170 T 23-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 Pfam PF00067 Cytochrome P450 187 374 1.9E-21 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 PRINTS PR00359 B-class P450 signature 353 364 5.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 PRINTS PR00359 B-class P450 signature 143 159 5.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 PRINTS PR00359 B-class P450 signature 277 288 5.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 PRINTS PR00359 B-class P450 signature 323 338 5.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 PRINTS PR00359 B-class P450 signature 344 353 5.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 PRINTS PR00359 B-class P450 signature 196 218 5.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 PRINTS PR00359 B-class P450 signature 160 175 5.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 PRINTS PR00359 B-class P450 signature 295 322 5.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 PRINTS PR00359 B-class P450 signature 97 108 5.2E-59 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 PANTHER PTHR11712 4 402 5.5E-116 T 23-04-2016 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 SUPERFAMILY SSF48264 8 404 9.43E-106 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 Gene3D G3DSA:1.10.630.10 4 403 2.1E-137 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS26960 f1d9ec6af7de262b35726015746a358e 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS38945 b3629b97410e4e8d347df811520622ac 173 PANTHER PTHR33164:SF10 1 171 6.0E-31 T 23-04-2016 DC74_RS38945 b3629b97410e4e8d347df811520622ac 173 PANTHER PTHR33164 1 171 6.0E-31 T 23-04-2016 DC74_RS38945 b3629b97410e4e8d347df811520622ac 173 SMART SM00347 45 147 3.6E-16 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS38945 b3629b97410e4e8d347df811520622ac 173 Pfam PF01047 MarR family 54 112 4.7E-16 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS38945 b3629b97410e4e8d347df811520622ac 173 Gene3D G3DSA:1.10.10.10 16 160 1.8E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38945 b3629b97410e4e8d347df811520622ac 173 SUPERFAMILY SSF46785 17 161 1.01E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28555 caefb3d3850c5dee7f4bc730ecb0f459 265 SUPERFAMILY SSF140453 6 82 5.62E-8 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS28555 caefb3d3850c5dee7f4bc730ecb0f459 265 Gene3D G3DSA:1.10.287.1060 7 84 9.3E-5 T 23-04-2016 DC74_RS28555 caefb3d3850c5dee7f4bc730ecb0f459 265 Pfam PF06013 Proteins of 100 residues with WXG 7 82 9.9E-8 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS17425 1e7350b2af22a56860d4fc9fa9885543 713 Pfam PF02384 N-6 DNA Methylase 178 390 4.6E-31 T 23-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 DC74_RS17425 1e7350b2af22a56860d4fc9fa9885543 713 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 200 214 3.4E-11 T 23-04-2016 DC74_RS17425 1e7350b2af22a56860d4fc9fa9885543 713 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 285 297 3.4E-11 T 23-04-2016 DC74_RS17425 1e7350b2af22a56860d4fc9fa9885543 713 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 319 343 3.4E-11 T 23-04-2016 DC74_RS17425 1e7350b2af22a56860d4fc9fa9885543 713 PANTHER PTHR30408 199 373 3.3E-12 T 23-04-2016 DC74_RS17425 1e7350b2af22a56860d4fc9fa9885543 713 SUPERFAMILY SSF53335 155 393 3.5E-44 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS17425 1e7350b2af22a56860d4fc9fa9885543 713 PANTHER PTHR30408:SF4 199 373 3.3E-12 T 23-04-2016 DC74_RS17425 1e7350b2af22a56860d4fc9fa9885543 713 Gene3D G3DSA:3.40.50.150 166 374 2.2E-26 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS35100 819896ee21b7326216badf00190eb588 402 PANTHER PTHR24423:SF508 101 363 1.9E-31 T 23-04-2016 DC74_RS35100 819896ee21b7326216badf00190eb588 402 SUPERFAMILY SSF55874 155 282 1.7E-15 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35100 819896ee21b7326216badf00190eb588 402 PANTHER PTHR24423 101 363 1.9E-31 T 23-04-2016 DC74_RS35100 819896ee21b7326216badf00190eb588 402 Gene3D G3DSA:3.30.565.10 171 280 7.6E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35100 819896ee21b7326216badf00190eb588 402 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 176 281 1.2E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS26390 d283ec88ecd501b8213540fcc11ff125 209 Hamap MF_00163 Peptide deformylase [def]. 33 199 28.478 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS26390 d283ec88ecd501b8213540fcc11ff125 209 Gene3D G3DSA:3.90.45.10 35 200 5.0E-57 T 23-04-2016 IPR023635 Peptide deformylase DC74_RS26390 d283ec88ecd501b8213540fcc11ff125 209 PRINTS PR01576 Peptide deformylase signature 126 137 7.3E-33 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS26390 d283ec88ecd501b8213540fcc11ff125 209 PRINTS PR01576 Peptide deformylase signature 64 93 7.3E-33 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS26390 d283ec88ecd501b8213540fcc11ff125 209 PRINTS PR01576 Peptide deformylase signature 138 156 7.3E-33 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS26390 d283ec88ecd501b8213540fcc11ff125 209 PRINTS PR01576 Peptide deformylase signature 157 186 7.3E-33 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS26390 d283ec88ecd501b8213540fcc11ff125 209 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 40 196 3.6E-39 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS26390 d283ec88ecd501b8213540fcc11ff125 209 PIRSF PIRSF004749 2 207 7.5E-44 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS26390 d283ec88ecd501b8213540fcc11ff125 209 PANTHER PTHR10458 10 200 3.7E-59 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 DC74_RS26390 d283ec88ecd501b8213540fcc11ff125 209 Pfam PF01327 Polypeptide deformylase 35 189 2.7E-43 T 23-04-2016 IPR023635 Peptide deformylase DC74_RS26390 d283ec88ecd501b8213540fcc11ff125 209 SUPERFAMILY SSF56420 33 196 1.96E-53 T 23-04-2016 IPR023635 Peptide deformylase DC74_RS07640 073d98aace0857c63188347f0b26d148 255 Gene3D G3DSA:3.40.630.30 130 250 3.8E-13 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS07640 073d98aace0857c63188347f0b26d148 255 Pfam PF00583 Acetyltransferase (GNAT) family 192 244 3.7E-5 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS07640 073d98aace0857c63188347f0b26d148 255 SUPERFAMILY SSF55729 77 253 1.26E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS27710 7b122b9f51ce9557dd18aa96f8ecf87d 575 SUPERFAMILY SSF56300 237 264 3.2E-31 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS27710 7b122b9f51ce9557dd18aa96f8ecf87d 575 SUPERFAMILY SSF56300 92 178 3.2E-31 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS27710 7b122b9f51ce9557dd18aa96f8ecf87d 575 SUPERFAMILY SSF56300 331 509 3.2E-31 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS27710 7b122b9f51ce9557dd18aa96f8ecf87d 575 Gene3D G3DSA:3.60.21.10 320 509 3.1E-58 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS27710 7b122b9f51ce9557dd18aa96f8ecf87d 575 Gene3D G3DSA:3.60.21.10 237 252 3.1E-58 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS27710 7b122b9f51ce9557dd18aa96f8ecf87d 575 Gene3D G3DSA:3.60.21.10 89 178 3.1E-58 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS27710 7b122b9f51ce9557dd18aa96f8ecf87d 575 TIGRFAM TIGR03767 P_acnes_RR: metallophosphoesterase, PPA1498 family 58 573 1.2E-215 T 23-04-2016 IPR022506 Metallophosphoesterase, PPA1498 DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 Gene3D G3DSA:3.30.565.10 393 547 5.3E-32 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 SUPERFAMILY SSF55785 217 314 5.98E-6 T 23-04-2016 IPR000014 PAS domain DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 PANTHER PTHR24423 202 547 9.4E-81 T 23-04-2016 DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 PANTHER PTHR24423 38 169 9.4E-81 T 23-04-2016 DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 PANTHER PTHR24423:SF379 202 547 9.4E-81 T 23-04-2016 DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 PANTHER PTHR24423:SF379 38 169 9.4E-81 T 23-04-2016 DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 432 544 2.7E-17 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 542 6.6E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 486 6.6E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 523 6.6E-11 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 Pfam PF17203 Single cache domain 3 46 181 1.3E-27 T 23-04-2016 IPR033463 Single cache domain 3 DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 SUPERFAMILY SSF103190 47 181 2.71E-29 T 23-04-2016 IPR029151 Periplasmic sensor domain-like DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 SMART SM00387 429 545 3.1E-25 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 Gene3D G3DSA:3.30.450.20 42 181 2.4E-37 T 23-04-2016 DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 SUPERFAMILY SSF55874 403 545 2.23E-28 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 SUPERFAMILY SSF55890 332 399 5.49E-5 T 23-04-2016 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 Gene3D G3DSA:3.30.450.20 226 318 8.8E-7 T 23-04-2016 DC74_RS27305 23d74c1191de1885e43a5bee1192312d 552 Gene3D G3DSA:1.10.287.130 319 379 3.0E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 DC74_RS30780 cd04b0a1a634d718e778712c67187bc7 404 SUPERFAMILY SSF53335 10 220 6.53E-33 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS30780 cd04b0a1a634d718e778712c67187bc7 404 Gene3D G3DSA:3.40.50.150 9 223 1.2E-47 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS30780 cd04b0a1a634d718e778712c67187bc7 404 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 13 221 1.7E-37 T 23-04-2016 DC74_RS30780 cd04b0a1a634d718e778712c67187bc7 404 PANTHER PTHR11579:SF0 1 202 1.7E-40 T 23-04-2016 DC74_RS30780 cd04b0a1a634d718e778712c67187bc7 404 PANTHER PTHR11579 1 202 1.7E-40 T 23-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 DC74_RS30780 cd04b0a1a634d718e778712c67187bc7 404 TIGRFAM TIGR04364 methyltran_FxLD: methyltransferase, FxLD system 8 401 8.2E-166 T 23-04-2016 IPR027573 Methyltransferase, FxLD system DC74_RS15880 23f563ba0b6f143268dfe1f147bfb746 323 SUPERFAMILY SSF52768 9 315 6.48E-98 T 23-04-2016 DC74_RS15880 23f563ba0b6f143268dfe1f147bfb746 323 PANTHER PTHR11358 1 316 2.4E-113 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS15880 23f563ba0b6f143268dfe1f147bfb746 323 TIGRFAM TIGR01230 agmatinase: agmatinase 40 311 2.2E-70 T 23-04-2016 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|UniPathway: UPA00534 DC74_RS15880 23f563ba0b6f143268dfe1f147bfb746 323 PANTHER PTHR11358:SF26 1 316 2.4E-113 T 23-04-2016 DC74_RS15880 23f563ba0b6f143268dfe1f147bfb746 323 PIRSF PIRSF036979 20 318 2.9E-109 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS15880 23f563ba0b6f143268dfe1f147bfb746 323 PRINTS PR00116 Arginase signature 126 141 1.6E-14 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS15880 23f563ba0b6f143268dfe1f147bfb746 323 PRINTS PR00116 Arginase signature 239 268 1.6E-14 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS15880 23f563ba0b6f143268dfe1f147bfb746 323 ProSitePatterns PS01053 Arginase family signature. 242 263 - T 23-04-2016 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 Reactome: REACT_13 DC74_RS15880 23f563ba0b6f143268dfe1f147bfb746 323 Gene3D G3DSA:3.40.800.10 13 316 8.0E-117 T 23-04-2016 IPR023696 Ureohydrolase domain DC74_RS15880 23f563ba0b6f143268dfe1f147bfb746 323 Pfam PF00491 Arginase family 40 310 2.7E-91 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS30160 2a32f4a42b17968e8ef0fa9eb3e6c9f0 160 Pfam PF00741 Gas vesicle protein 21 59 8.4E-11 T 23-04-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 DC74_RS30160 2a32f4a42b17968e8ef0fa9eb3e6c9f0 160 PANTHER PTHR35344:SF3 15 133 1.4E-58 T 23-04-2016 DC74_RS30160 2a32f4a42b17968e8ef0fa9eb3e6c9f0 160 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 22 36 - T 23-04-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 DC74_RS30160 2a32f4a42b17968e8ef0fa9eb3e6c9f0 160 PANTHER PTHR35344 15 133 1.4E-58 T 23-04-2016 DC74_RS30160 2a32f4a42b17968e8ef0fa9eb3e6c9f0 160 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 55 68 - T 23-04-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 DC74_RS30160 2a32f4a42b17968e8ef0fa9eb3e6c9f0 160 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 10 98 27.777 T 23-04-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 DC74_RS33465 4ad146abd7a2089e75acfae76f3c61b2 288 SUPERFAMILY SSF47413 19 76 2.0E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS33465 4ad146abd7a2089e75acfae76f3c61b2 288 SUPERFAMILY SSF48498 167 280 1.39E-20 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS33465 4ad146abd7a2089e75acfae76f3c61b2 288 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 101 114 3.54E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS33465 4ad146abd7a2089e75acfae76f3c61b2 288 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 122 145 3.54E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS33465 4ad146abd7a2089e75acfae76f3c61b2 288 PANTHER PTHR30328 97 273 4.1E-33 T 23-04-2016 DC74_RS33465 4ad146abd7a2089e75acfae76f3c61b2 288 Pfam PF00440 Bacterial regulatory proteins, tetR family 101 147 3.9E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS33465 4ad146abd7a2089e75acfae76f3c61b2 288 SMART SM00530 19 74 1.1E-4 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS33465 4ad146abd7a2089e75acfae76f3c61b2 288 SUPERFAMILY SSF46689 98 170 1.08E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS33465 4ad146abd7a2089e75acfae76f3c61b2 288 Pfam PF13977 Bacterial transcriptional repressor 170 283 2.6E-28 T 23-04-2016 DC74_RS33465 4ad146abd7a2089e75acfae76f3c61b2 288 Gene3D G3DSA:1.10.260.40 16 77 6.8E-8 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS33465 4ad146abd7a2089e75acfae76f3c61b2 288 PANTHER PTHR30328:SF11 97 273 4.1E-33 T 23-04-2016 DC74_RS33465 4ad146abd7a2089e75acfae76f3c61b2 288 Gene3D G3DSA:1.10.357.10 85 280 2.9E-42 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS40180 71cc5208a56e1d9b4fef28b657525a9c 158 Gene3D G3DSA:3.30.565.10 32 151 2.8E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS40180 71cc5208a56e1d9b4fef28b657525a9c 158 SUPERFAMILY SSF55874 45 149 1.13E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS40180 71cc5208a56e1d9b4fef28b657525a9c 158 Pfam PF13581 Histidine kinase-like ATPase domain 29 133 4.0E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS24665 249ee734d044b4c2e0a422a27228583b 65 Pfam PF04149 Domain of unknown function (DUF397) 9 60 1.6E-21 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS19345 cf4fec1450d69279161bf3e30383915e 152 SUPERFAMILY SSF101386 57 131 2.62E-8 T 23-04-2016 DC74_RS09960 07e81b7dd455bba308277b376815cf74 257 SUPERFAMILY SSF46894 177 244 1.26E-16 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS09960 07e81b7dd455bba308277b376815cf74 257 Gene3D G3DSA:1.10.10.10 178 244 1.4E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS09960 07e81b7dd455bba308277b376815cf74 257 SMART SM00421 184 241 1.9E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS09960 07e81b7dd455bba308277b376815cf74 257 ProSitePatterns PS00622 LuxR-type HTH domain signature. 201 228 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS09960 07e81b7dd455bba308277b376815cf74 257 Pfam PF00196 Bacterial regulatory proteins, luxR family 188 239 5.1E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS09960 07e81b7dd455bba308277b376815cf74 257 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 217 229 4.4E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS09960 07e81b7dd455bba308277b376815cf74 257 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 201 217 4.4E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS09960 07e81b7dd455bba308277b376815cf74 257 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 201 4.4E-11 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS33320 a5b4aa7a8a76570db5cf2f1d2208f750 469 PANTHER PTHR10617 11 456 8.9E-73 T 23-04-2016 DC74_RS33320 a5b4aa7a8a76570db5cf2f1d2208f750 469 SUPERFAMILY SSF51905 316 396 1.3E-22 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33320 a5b4aa7a8a76570db5cf2f1d2208f750 469 SUPERFAMILY SSF51905 9 200 1.3E-22 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33320 a5b4aa7a8a76570db5cf2f1d2208f750 469 Gene3D G3DSA:3.50.50.60 12 205 2.5E-16 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33320 a5b4aa7a8a76570db5cf2f1d2208f750 469 Gene3D G3DSA:3.50.50.60 319 358 2.5E-16 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33320 a5b4aa7a8a76570db5cf2f1d2208f750 469 PANTHER PTHR10617:SF114 11 456 8.9E-73 T 23-04-2016 DC74_RS10675 a4f2390e1485ad23c8f69aff6e8e7d5c 242 Pfam PF05853 beta-keto acid cleavage enzyme 2 238 1.1E-27 T 23-04-2016 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24|UniPathway: UPA00870 DC74_RS10675 a4f2390e1485ad23c8f69aff6e8e7d5c 242 PANTHER PTHR37418:SF1 1 231 2.8E-94 T 23-04-2016 DC74_RS10675 a4f2390e1485ad23c8f69aff6e8e7d5c 242 SUPERFAMILY SSF51366 21 132 5.65E-5 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 DC74_RS10675 a4f2390e1485ad23c8f69aff6e8e7d5c 242 PANTHER PTHR37418 1 231 2.8E-94 T 23-04-2016 DC74_RS10675 a4f2390e1485ad23c8f69aff6e8e7d5c 242 Gene3D G3DSA:3.20.20.70 2 238 9.5E-45 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS38085 791df580d89e95b6871d07d152b95bef 173 Pfam PF12802 MarR family 57 103 1.3E-7 T 23-04-2016 DC74_RS38085 791df580d89e95b6871d07d152b95bef 173 Gene3D G3DSA:1.10.10.10 14 133 1.2E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38085 791df580d89e95b6871d07d152b95bef 173 SUPERFAMILY SSF46785 15 133 1.89E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01160 2c3aa939fc266858551cfb45a8383955 330 PANTHER PTHR23026 244 329 9.7E-31 T 23-04-2016 DC74_RS01160 2c3aa939fc266858551cfb45a8383955 330 PANTHER PTHR23026:SF111 244 329 9.7E-31 T 23-04-2016 DC74_RS01160 2c3aa939fc266858551cfb45a8383955 330 PANTHER PTHR23026 7 38 9.7E-31 T 23-04-2016 DC74_RS01160 2c3aa939fc266858551cfb45a8383955 330 PANTHER PTHR23026 138 203 9.7E-31 T 23-04-2016 DC74_RS01160 2c3aa939fc266858551cfb45a8383955 330 SUPERFAMILY SSF55469 121 327 8.98E-8 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS01160 2c3aa939fc266858551cfb45a8383955 330 PANTHER PTHR23026:SF111 7 38 9.7E-31 T 23-04-2016 DC74_RS01160 2c3aa939fc266858551cfb45a8383955 330 PANTHER PTHR23026:SF111 138 203 9.7E-31 T 23-04-2016 DC74_RS01160 2c3aa939fc266858551cfb45a8383955 330 Gene3D G3DSA:3.40.109.10 7 70 1.6E-25 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS01160 2c3aa939fc266858551cfb45a8383955 330 Gene3D G3DSA:3.40.109.10 195 328 1.6E-25 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS01160 2c3aa939fc266858551cfb45a8383955 330 SUPERFAMILY SSF55469 6 85 4.28E-7 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS23120 2e95e40118888948032474fb854c2a2c 326 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 229 303 6.1E-9 T 23-04-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 DC74_RS23120 2e95e40118888948032474fb854c2a2c 326 PANTHER PTHR22602 2 289 2.7E-19 T 23-04-2016 DC74_RS23120 2e95e40118888948032474fb854c2a2c 326 Pfam PF01571 Aminomethyltransferase folate-binding domain 27 146 1.1E-19 T 23-04-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal DC74_RS23120 2e95e40118888948032474fb854c2a2c 326 SUPERFAMILY SSF103025 27 245 3.45E-53 T 23-04-2016 DC74_RS23120 2e95e40118888948032474fb854c2a2c 326 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 191 255 1.6E-20 T 23-04-2016 IPR017703 YgfZ/GcvT conserved site DC74_RS23120 2e95e40118888948032474fb854c2a2c 326 Gene3D G3DSA:3.30.70.1400 52 136 2.2E-12 T 23-04-2016 DC74_RS23120 2e95e40118888948032474fb854c2a2c 326 PANTHER PTHR22602:SF0 2 289 2.7E-19 T 23-04-2016 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 PANTHER PTHR11739 7 373 8.6E-142 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 Pfam PF00285 Citrate synthase, C-terminal domain 11 362 1.5E-121 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 PRINTS PR00143 Citrate synthase signature 200 228 6.8E-40 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 PRINTS PR00143 Citrate synthase signature 129 142 6.8E-40 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 PRINTS PR00143 Citrate synthase signature 178 193 6.8E-40 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 PRINTS PR00143 Citrate synthase signature 313 329 6.8E-40 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 PRINTS PR00143 Citrate synthase signature 253 273 6.8E-40 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 PRINTS PR00143 Citrate synthase signature 333 347 6.8E-40 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 SUPERFAMILY SSF48256 8 373 3.4E-123 T 23-04-2016 IPR002020 Citrate synthase GO:0046912 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 ProSitePatterns PS00480 Citrate synthase signature. 260 272 - T 23-04-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 Gene3D G3DSA:1.10.230.10 240 327 7.7E-28 T 23-04-2016 IPR016143 Citrate synthase-like, small alpha subdomain DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 PIRSF PIRSF001369 3 378 3.7E-122 T 23-04-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 PANTHER PTHR11739:SF4 7 373 8.6E-142 T 23-04-2016 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 10 373 3.6E-140 T 23-04-2016 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 DC74_RS04995 636e6c948af9a54236f244719fd89ee0 378 Gene3D G3DSA:1.10.580.10 19 239 1.3E-85 T 23-04-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 DC74_RS24850 6204fcfa14b073f2f4f024671384a511 329 Gene3D G3DSA:1.25.40.10 218 301 6.9E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS24850 6204fcfa14b073f2f4f024671384a511 329 Gene3D G3DSA:1.25.40.10 98 132 6.9E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS10890 4a0ed7869269df79d433f28cc81b4d58 253 PIRSF PIRSF039085 1 253 2.1E-116 T 23-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 DC74_RS10890 4a0ed7869269df79d433f28cc81b4d58 253 Pfam PF00005 ABC transporter 20 178 1.6E-33 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS10890 4a0ed7869269df79d433f28cc81b4d58 253 PANTHER PTHR24220 6 253 2.0E-132 T 23-04-2016 DC74_RS10890 4a0ed7869269df79d433f28cc81b4d58 253 PANTHER PTHR24220:SF447 6 253 2.0E-132 T 23-04-2016 DC74_RS10890 4a0ed7869269df79d433f28cc81b4d58 253 Gene3D G3DSA:3.40.50.300 3 250 1.6E-85 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10890 4a0ed7869269df79d433f28cc81b4d58 253 SUPERFAMILY SSF52540 4 248 1.49E-78 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10890 4a0ed7869269df79d433f28cc81b4d58 253 SMART SM00382 29 226 4.6E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS10890 4a0ed7869269df79d433f28cc81b4d58 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS30280 addda60b3da0d59d348e8f1ded7bff73 124 PANTHER PTHR30007:SF0 1 120 7.9E-23 T 23-04-2016 DC74_RS30280 addda60b3da0d59d348e8f1ded7bff73 124 Pfam PF01609 Transposase DDE domain 2 114 3.7E-13 T 23-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 DC74_RS30280 addda60b3da0d59d348e8f1ded7bff73 124 PANTHER PTHR30007 1 120 7.9E-23 T 23-04-2016 DC74_RS15150 6ddf4d9cd49e749c8c65efdaa3e9237a 217 Gene3D G3DSA:3.40.50.1240 10 205 4.2E-57 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS15150 6ddf4d9cd49e749c8c65efdaa3e9237a 217 SUPERFAMILY SSF53254 10 208 5.41E-54 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS15150 6ddf4d9cd49e749c8c65efdaa3e9237a 217 SMART SM00855 11 165 4.4E-23 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS15150 6ddf4d9cd49e749c8c65efdaa3e9237a 217 PANTHER PTHR23029 8 204 5.6E-47 T 23-04-2016 DC74_RS15150 6ddf4d9cd49e749c8c65efdaa3e9237a 217 PANTHER PTHR23029:SF1 8 204 5.6E-47 T 23-04-2016 DC74_RS15150 6ddf4d9cd49e749c8c65efdaa3e9237a 217 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 14 23 - T 23-04-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 DC74_RS15150 6ddf4d9cd49e749c8c65efdaa3e9237a 217 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 12 204 1.0E-53 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS36770 1d6c3f5fc4b540e2dd8cc669a7ce3d3f 188 Pfam PF11127 Protein of unknown function (DUF2892) 115 169 4.2E-11 T 23-04-2016 IPR021309 Protein of unknown function DUF2892 DC74_RS36770 1d6c3f5fc4b540e2dd8cc669a7ce3d3f 188 Pfam PF00581 Rhodanese-like domain 10 98 2.5E-12 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS36770 1d6c3f5fc4b540e2dd8cc669a7ce3d3f 188 SMART SM00450 5 102 9.3E-16 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS36770 1d6c3f5fc4b540e2dd8cc669a7ce3d3f 188 Gene3D G3DSA:3.40.250.10 4 103 7.8E-24 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS36770 1d6c3f5fc4b540e2dd8cc669a7ce3d3f 188 SUPERFAMILY SSF52821 4 105 1.44E-26 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS34300 36632703a8327dfd07b87c58d31a598b 422 PANTHER PTHR10742:SF275 4 422 7.5E-115 T 23-04-2016 DC74_RS34300 36632703a8327dfd07b87c58d31a598b 422 PANTHER PTHR10742 4 422 7.5E-115 T 23-04-2016 DC74_RS34300 36632703a8327dfd07b87c58d31a598b 422 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 4.6E-6 T 23-04-2016 DC74_RS34300 36632703a8327dfd07b87c58d31a598b 422 PRINTS PR00419 Adrenodoxin reductase family signature 28 41 4.6E-6 T 23-04-2016 DC74_RS34300 36632703a8327dfd07b87c58d31a598b 422 Gene3D G3DSA:3.50.50.60 5 98 1.9E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS34300 36632703a8327dfd07b87c58d31a598b 422 Gene3D G3DSA:3.50.50.60 145 146 1.9E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS34300 36632703a8327dfd07b87c58d31a598b 422 Gene3D G3DSA:3.50.50.60 207 292 1.9E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS34300 36632703a8327dfd07b87c58d31a598b 422 SUPERFAMILY SSF51905 6 306 2.78E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS34300 36632703a8327dfd07b87c58d31a598b 422 SUPERFAMILY SSF51905 387 418 2.78E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS34300 36632703a8327dfd07b87c58d31a598b 422 Pfam PF01593 Flavin containing amine oxidoreductase 13 278 1.3E-26 T 23-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 DC74_RS38650 055448f404703abe5580ed2512835828 321 SUPERFAMILY SSF56235 35 147 5.4E-5 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal DC74_RS38650 055448f404703abe5580ed2512835828 321 PANTHER PTHR34180 1 296 4.1E-22 T 23-04-2016 DC74_RS38650 055448f404703abe5580ed2512835828 321 Gene3D G3DSA:3.60.60.10 88 148 8.2E-6 T 23-04-2016 IPR003199 Choloylglycine hydrolase/Peptidase C59 family GO:0016811 DC74_RS38650 055448f404703abe5580ed2512835828 321 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 44 231 1.5E-16 T 23-04-2016 IPR005079 Peptidase C45 DC74_RS31345 d673c1d8f007c9c93f444988ffd861b7 132 Gene3D G3DSA:2.60.40.180 9 132 5.1E-35 T 23-04-2016 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily DC74_RS31345 d673c1d8f007c9c93f444988ffd861b7 132 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 10 132 2.3E-30 T 23-04-2016 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394 DC74_RS31345 d673c1d8f007c9c93f444988ffd861b7 132 PANTHER PTHR10395:SF7 10 132 6.8E-37 T 23-04-2016 DC74_RS31345 d673c1d8f007c9c93f444988ffd861b7 132 SUPERFAMILY SSF49472 7 132 1.02E-28 T 23-04-2016 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily DC74_RS31345 d673c1d8f007c9c93f444988ffd861b7 132 Pfam PF00576 HIUase/Transthyretin family 11 131 1.1E-34 T 23-04-2016 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily DC74_RS31345 d673c1d8f007c9c93f444988ffd861b7 132 PANTHER PTHR10395 10 132 6.8E-37 T 23-04-2016 DC74_RS20980 c97591948a34f2a301925de297c245b8 594 Pfam PF01964 Radical SAM ThiC family 135 554 4.9E-200 T 23-04-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 DC74_RS20980 c97591948a34f2a301925de297c245b8 594 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 133 560 55.717 T 23-04-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 DC74_RS20980 c97591948a34f2a301925de297c245b8 594 Pfam PF13667 ThiC-associated domain 24 87 1.3E-21 T 23-04-2016 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 DC74_RS20980 c97591948a34f2a301925de297c245b8 594 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 133 557 5.3E-212 T 23-04-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 DC74_RS20980 c97591948a34f2a301925de297c245b8 594 PANTHER PTHR30557:SF1 1 85 0.0 T 23-04-2016 DC74_RS20980 c97591948a34f2a301925de297c245b8 594 PANTHER PTHR30557:SF1 126 589 0.0 T 23-04-2016 DC74_RS20980 c97591948a34f2a301925de297c245b8 594 PANTHER PTHR30557 1 85 0.0 T 23-04-2016 DC74_RS20980 c97591948a34f2a301925de297c245b8 594 PANTHER PTHR30557 126 589 0.0 T 23-04-2016 DC74_RS14690 ac34b4f97b656fc994f0ca3b095ceeb7 289 SUPERFAMILY SSF51430 2 284 4.19E-76 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS14690 ac34b4f97b656fc994f0ca3b095ceeb7 289 Gene3D G3DSA:3.20.20.100 2 285 3.5E-75 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS14690 ac34b4f97b656fc994f0ca3b095ceeb7 289 Pfam PF00248 Aldo/keto reductase family 5 284 7.3E-62 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS14690 ac34b4f97b656fc994f0ca3b095ceeb7 289 PANTHER PTHR11732 1 284 1.3E-88 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS33825 2f7618258806ca3895a753da5e40b6dc 519 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 242 3.6E-50 T 23-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 DC74_RS33825 2f7618258806ca3895a753da5e40b6dc 519 Gene3D G3DSA:3.30.420.40 246 477 1.1E-41 T 23-04-2016 DC74_RS33825 2f7618258806ca3895a753da5e40b6dc 519 PIRSF PIRSF000538 1 489 3.6E-94 T 23-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 DC74_RS33825 2f7618258806ca3895a753da5e40b6dc 519 SUPERFAMILY SSF53067 3 247 2.99E-49 T 23-04-2016 DC74_RS33825 2f7618258806ca3895a753da5e40b6dc 519 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 353 373 - T 23-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 DC74_RS33825 2f7618258806ca3895a753da5e40b6dc 519 PANTHER PTHR10196 3 496 4.8E-70 T 23-04-2016 DC74_RS33825 2f7618258806ca3895a753da5e40b6dc 519 Gene3D G3DSA:3.30.420.40 3 244 7.7E-45 T 23-04-2016 DC74_RS33825 2f7618258806ca3895a753da5e40b6dc 519 SUPERFAMILY SSF53067 248 477 2.18E-47 T 23-04-2016 DC74_RS33825 2f7618258806ca3895a753da5e40b6dc 519 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 319 436 2.1E-24 T 23-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 DC74_RS12860 61d119409a10acbc8e469bf716226832 411 SMART SM00530 8 62 1.8E-11 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS12860 61d119409a10acbc8e469bf716226832 411 SUPERFAMILY SSF47413 5 65 1.21E-12 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS12860 61d119409a10acbc8e469bf716226832 411 Gene3D G3DSA:1.10.260.40 5 66 1.7E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS12860 61d119409a10acbc8e469bf716226832 411 Pfam PF13560 Helix-turn-helix domain 5 59 1.3E-11 T 23-04-2016 DC74_RS32665 0eb74297727a63f0f6ee45fee93ddcf6 148 Gene3D G3DSA:3.30.530.20 5 138 1.6E-10 T 23-04-2016 IPR023393 START-like domain DC74_RS32665 0eb74297727a63f0f6ee45fee93ddcf6 148 SUPERFAMILY SSF55961 7 141 9.99E-13 T 23-04-2016 DC74_RS32665 0eb74297727a63f0f6ee45fee93ddcf6 148 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 14 139 7.0E-11 T 23-04-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain DC74_RS26360 3d65a9aacc008522d8cf113e980795fc 215 PANTHER PTHR13136 20 214 8.2E-35 T 23-04-2016 IPR026555 KAT8 regulatory NSL complex subunit 3/Testis-expressed sequence 30 protein DC74_RS26360 3d65a9aacc008522d8cf113e980795fc 215 SUPERFAMILY SSF53474 7 212 1.62E-18 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS26360 3d65a9aacc008522d8cf113e980795fc 215 PANTHER PTHR13136:SF4 20 214 8.2E-35 T 23-04-2016 DC74_RS26360 3d65a9aacc008522d8cf113e980795fc 215 Gene3D G3DSA:3.40.50.1820 29 210 3.1E-16 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS13900 bc81c558dbd0eefee815e91d583ecc48 219 PANTHER PTHR10509 5 219 9.7E-73 T 23-04-2016 DC74_RS13900 bc81c558dbd0eefee815e91d583ecc48 219 Gene3D G3DSA:3.40.50.150 5 219 4.1E-68 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS13900 bc81c558dbd0eefee815e91d583ecc48 219 Pfam PF01596 O-methyltransferase 21 218 3.6E-49 T 23-04-2016 IPR002935 O-methyltransferase, family 3 GO:0008171 DC74_RS13900 bc81c558dbd0eefee815e91d583ecc48 219 PANTHER PTHR10509:SF14 5 219 9.7E-73 T 23-04-2016 DC74_RS13900 bc81c558dbd0eefee815e91d583ecc48 219 SUPERFAMILY SSF53335 11 219 4.18E-43 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS39320 eabdfc1cd77adfb60e46c3c2a7d7361f 234 SUPERFAMILY SSF53597 10 226 4.45E-41 T 23-04-2016 IPR024072 Dihydrofolate reductase-like domain DC74_RS39320 eabdfc1cd77adfb60e46c3c2a7d7361f 234 Gene3D G3DSA:3.40.430.10 6 229 2.6E-54 T 23-04-2016 IPR024072 Dihydrofolate reductase-like domain DC74_RS39320 eabdfc1cd77adfb60e46c3c2a7d7361f 234 Pfam PF01872 RibD C-terminal domain 11 219 2.7E-38 T 23-04-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 DC74_RS01235 0c1f5a511ce679e131f419277ced3a75 296 Pfam PF03988 Repeat of Unknown Function (DUF347) 168 213 6.5E-15 T 23-04-2016 IPR007136 Protein of unknown function DUF347 DC74_RS01235 0c1f5a511ce679e131f419277ced3a75 296 Pfam PF03988 Repeat of Unknown Function (DUF347) 223 278 1.3E-14 T 23-04-2016 IPR007136 Protein of unknown function DUF347 DC74_RS01235 0c1f5a511ce679e131f419277ced3a75 296 Pfam PF03988 Repeat of Unknown Function (DUF347) 85 152 2.7E-15 T 23-04-2016 IPR007136 Protein of unknown function DUF347 DC74_RS01235 0c1f5a511ce679e131f419277ced3a75 296 Pfam PF03988 Repeat of Unknown Function (DUF347) 29 80 2.8E-16 T 23-04-2016 IPR007136 Protein of unknown function DUF347 DC74_RS24880 5279921ad9635b8285e092ed59a41304 394 PANTHER PTHR23028 21 390 6.2E-79 T 23-04-2016 DC74_RS24880 5279921ad9635b8285e092ed59a41304 394 PANTHER PTHR23028:SF79 21 390 6.2E-79 T 23-04-2016 DC74_RS24880 5279921ad9635b8285e092ed59a41304 394 Pfam PF01757 Acyltransferase family 48 375 1.0E-22 T 23-04-2016 IPR002656 Acyltransferase 3 GO:0016747 DC74_RS04155 118d1e0f6503015edef443dbe345be69 258 SUPERFAMILY SSF53335 5 243 2.43E-37 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS04155 118d1e0f6503015edef443dbe345be69 258 PANTHER PTHR10108 4 161 4.1E-28 T 23-04-2016 DC74_RS04155 118d1e0f6503015edef443dbe345be69 258 PANTHER PTHR10108 190 241 4.1E-28 T 23-04-2016 DC74_RS04155 118d1e0f6503015edef443dbe345be69 258 Gene3D G3DSA:3.40.50.150 5 242 5.9E-33 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS04155 118d1e0f6503015edef443dbe345be69 258 Pfam PF13649 Methyltransferase domain 52 148 2.1E-19 T 23-04-2016 DC74_RS01295 8b0713d5f23e02d0ec66ffcff7d4b834 132 Pfam PF00741 Gas vesicle protein 18 56 1.7E-16 T 23-04-2016 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 DC74_RS01295 8b0713d5f23e02d0ec66ffcff7d4b834 132 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 19 33 - T 23-04-2016 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 DC74_RS01295 8b0713d5f23e02d0ec66ffcff7d4b834 132 PANTHER PTHR35344 4 120 7.9E-39 T 23-04-2016 DC74_RS01295 8b0713d5f23e02d0ec66ffcff7d4b834 132 PANTHER PTHR35344:SF1 4 120 7.9E-39 T 23-04-2016 DC74_RS06715 38f41041b788b05c2e885ee16c285ab0 179 Pfam PF13671 AAA domain 6 126 2.2E-10 T 23-04-2016 DC74_RS06715 38f41041b788b05c2e885ee16c285ab0 179 SUPERFAMILY SSF52540 5 171 4.11E-17 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS06715 38f41041b788b05c2e885ee16c285ab0 179 Gene3D G3DSA:3.40.50.300 4 171 7.8E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS08745 a439d42b8e433493f640fdb34f0d02f6 152 Pfam PF13581 Histidine kinase-like ATPase domain 30 146 1.4E-15 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS08745 a439d42b8e433493f640fdb34f0d02f6 152 SUPERFAMILY SSF55874 57 150 1.96E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS08745 a439d42b8e433493f640fdb34f0d02f6 152 Gene3D G3DSA:3.30.565.10 32 119 2.6E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS14875 ba5f680afaf4ab164e9b70274eb5ed06 540 SUPERFAMILY SSF51338 494 537 9.05E-20 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS14875 ba5f680afaf4ab164e9b70274eb5ed06 540 SUPERFAMILY SSF51338 4 63 9.05E-20 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS14875 ba5f680afaf4ab164e9b70274eb5ed06 540 Gene3D G3DSA:3.20.20.140 66 85 1.8E-43 T 23-04-2016 DC74_RS14875 ba5f680afaf4ab164e9b70274eb5ed06 540 Gene3D G3DSA:3.20.20.140 201 479 1.8E-43 T 23-04-2016 DC74_RS14875 ba5f680afaf4ab164e9b70274eb5ed06 540 PANTHER PTHR22642:SF2 24 532 1.4E-125 T 23-04-2016 DC74_RS14875 ba5f680afaf4ab164e9b70274eb5ed06 540 PANTHER PTHR22642 24 532 1.4E-125 T 23-04-2016 DC74_RS14875 ba5f680afaf4ab164e9b70274eb5ed06 540 Gene3D G3DSA:2.30.40.10 480 506 1.0E-5 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS14875 ba5f680afaf4ab164e9b70274eb5ed06 540 Gene3D G3DSA:2.30.40.10 3 64 1.7E-15 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS14875 ba5f680afaf4ab164e9b70274eb5ed06 540 Gene3D G3DSA:2.30.40.10 507 536 1.7E-15 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS14875 ba5f680afaf4ab164e9b70274eb5ed06 540 Pfam PF07969 Amidohydrolase family 52 534 2.8E-80 T 23-04-2016 IPR013108 Amidohydrolase 3 DC74_RS14875 ba5f680afaf4ab164e9b70274eb5ed06 540 SUPERFAMILY SSF51556 195 495 5.45E-37 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS14875 ba5f680afaf4ab164e9b70274eb5ed06 540 SUPERFAMILY SSF51556 62 119 5.45E-37 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS33690 2c6180189923e0c3158be883810d5d68 346 SUPERFAMILY SSF51695 35 200 2.27E-11 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS33690 2c6180189923e0c3158be883810d5d68 346 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 106 199 1.4E-12 T 23-04-2016 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent DC74_RS31680 581fc6595aa10ce423f528f3311c2902 248 SUPERFAMILY SSF52467 14 247 3.18E-68 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS31680 581fc6595aa10ce423f528f3311c2902 248 Gene3D G3DSA:3.40.50.1220 14 29 1.7E-36 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS31680 581fc6595aa10ce423f528f3311c2902 248 Gene3D G3DSA:3.40.50.1220 81 120 1.7E-36 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS31680 581fc6595aa10ce423f528f3311c2902 248 Gene3D G3DSA:3.40.50.1220 175 246 1.7E-36 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain DC74_RS31680 581fc6595aa10ce423f528f3311c2902 248 PANTHER PTHR11085 14 247 1.8E-81 T 23-04-2016 IPR003000 Sirtuin family GO:0070403 DC74_RS31680 581fc6595aa10ce423f528f3311c2902 248 Gene3D G3DSA:3.30.1600.10 30 69 1.4E-22 T 23-04-2016 IPR026591 Sirtuin family, catalytic core small domain DC74_RS31680 581fc6595aa10ce423f528f3311c2902 248 Gene3D G3DSA:3.30.1600.10 121 168 1.4E-22 T 23-04-2016 IPR026591 Sirtuin family, catalytic core small domain DC74_RS31680 581fc6595aa10ce423f528f3311c2902 248 Pfam PF02146 Sir2 family 19 199 1.7E-43 T 23-04-2016 IPR003000 Sirtuin family GO:0070403 DC74_RS14960 8753cc3f8c15317623e157aacd711121 165 PANTHER PTHR22881 13 154 4.8E-45 T 23-04-2016 DC74_RS14960 8753cc3f8c15317623e157aacd711121 165 Gene3D G3DSA:3.40.390.30 5 156 6.6E-43 T 23-04-2016 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 DC74_RS14960 8753cc3f8c15317623e157aacd711121 165 Pfam PF02130 Uncharacterized protein family UPF0054 15 147 7.2E-36 T 23-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 DC74_RS14960 8753cc3f8c15317623e157aacd711121 165 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 119 129 - T 23-04-2016 IPR020549 Endoribonuclease YbeY, conserved site DC74_RS14960 8753cc3f8c15317623e157aacd711121 165 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 4.3E-31 T 23-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 DC74_RS14960 8753cc3f8c15317623e157aacd711121 165 SUPERFAMILY SSF55486 3 149 6.1E-37 T 23-04-2016 DC74_RS14960 8753cc3f8c15317623e157aacd711121 165 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 157 21.352 T 23-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 DC74_RS21915 0674574850175e542d0c52b471d822d7 199 SUPERFAMILY SSF53335 30 172 6.14E-9 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS21915 0674574850175e542d0c52b471d822d7 199 PANTHER PTHR40036 6 170 1.7E-14 T 23-04-2016 DC74_RS21915 0674574850175e542d0c52b471d822d7 199 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 20 174 5.3E-24 T 23-04-2016 IPR008884 Macrocin-O-methyltransferase DC74_RS21915 0674574850175e542d0c52b471d822d7 199 Gene3D G3DSA:3.40.50.150 32 179 1.1E-6 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS21915 0674574850175e542d0c52b471d822d7 199 PANTHER PTHR40036:SF1 6 170 1.7E-14 T 23-04-2016 DC74_RS13340 1470d9ebf5f719945652a9e2da38c30e 345 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS13340 1470d9ebf5f719945652a9e2da38c30e 345 PANTHER PTHR24220:SF0 15 299 5.6E-104 T 23-04-2016 DC74_RS13340 1470d9ebf5f719945652a9e2da38c30e 345 SUPERFAMILY SSF52540 14 235 2.66E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS13340 1470d9ebf5f719945652a9e2da38c30e 345 SMART SM00382 38 230 5.7E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS13340 1470d9ebf5f719945652a9e2da38c30e 345 PANTHER PTHR24220 15 299 5.6E-104 T 23-04-2016 DC74_RS13340 1470d9ebf5f719945652a9e2da38c30e 345 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 21 320 5.7E-114 T 23-04-2016 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 KEGG: 00920+3.6.3.- DC74_RS13340 1470d9ebf5f719945652a9e2da38c30e 345 Gene3D G3DSA:3.40.50.300 8 238 9.5E-69 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS13340 1470d9ebf5f719945652a9e2da38c30e 345 Pfam PF00005 ABC transporter 30 172 1.5E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS02945 aa9ecbf69636d7edac5f8af42b310388 133 SMART SM00418 34 114 1.3E-28 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS02945 aa9ecbf69636d7edac5f8af42b310388 133 PANTHER PTHR33154 6 127 1.0E-42 T 23-04-2016 DC74_RS02945 aa9ecbf69636d7edac5f8af42b310388 133 PANTHER PTHR33154:SF4 6 127 1.0E-42 T 23-04-2016 DC74_RS02945 aa9ecbf69636d7edac5f8af42b310388 133 Pfam PF01022 Bacterial regulatory protein, arsR family 41 88 3.7E-16 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS02945 aa9ecbf69636d7edac5f8af42b310388 133 SUPERFAMILY SSF46785 20 114 1.19E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02945 aa9ecbf69636d7edac5f8af42b310388 133 Gene3D G3DSA:1.10.10.10 10 113 1.2E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS02945 aa9ecbf69636d7edac5f8af42b310388 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 86 101 7.2E-23 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS02945 aa9ecbf69636d7edac5f8af42b310388 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 7.2E-23 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS02945 aa9ecbf69636d7edac5f8af42b310388 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 69 7.2E-23 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS02945 aa9ecbf69636d7edac5f8af42b310388 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 7.2E-23 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS02945 aa9ecbf69636d7edac5f8af42b310388 133 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 60 78 - T 23-04-2016 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 DC74_RS29215 1cb1f666a48d5316bb5269176d956496 227 PANTHER PTHR26402:SF603 2 226 1.6E-93 T 23-04-2016 DC74_RS29215 1cb1f666a48d5316bb5269176d956496 227 SUPERFAMILY SSF52172 3 183 4.41E-40 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS29215 1cb1f666a48d5316bb5269176d956496 227 Gene3D G3DSA:1.10.10.10 128 226 1.3E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29215 1cb1f666a48d5316bb5269176d956496 227 SMART SM00448 2 112 3.0E-41 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS29215 1cb1f666a48d5316bb5269176d956496 227 Pfam PF00072 Response regulator receiver domain 4 112 3.4E-29 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS29215 1cb1f666a48d5316bb5269176d956496 227 PANTHER PTHR26402 2 226 1.6E-93 T 23-04-2016 DC74_RS29215 1cb1f666a48d5316bb5269176d956496 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 1.1E-23 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS29215 1cb1f666a48d5316bb5269176d956496 227 Gene3D G3DSA:3.40.50.2300 3 122 4.8E-39 T 23-04-2016 DC74_RS29215 1cb1f666a48d5316bb5269176d956496 227 SMART SM00862 149 225 1.3E-24 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS09330 b6e20185326f8575e59fc16c1ebeee1c 147 Pfam PF01337 Barstar (barnase inhibitor) 47 129 1.7E-26 T 23-04-2016 IPR000468 Barstar (barnase inhibitor) DC74_RS09330 b6e20185326f8575e59fc16c1ebeee1c 147 SUPERFAMILY SSF52038 46 130 1.09E-21 T 23-04-2016 IPR000468 Barstar (barnase inhibitor) DC74_RS09330 b6e20185326f8575e59fc16c1ebeee1c 147 Gene3D G3DSA:3.30.370.10 47 130 3.8E-22 T 23-04-2016 IPR000468 Barstar (barnase inhibitor) DC74_RS23840 2e2b2c222a771ea0e2d2703618b312a0 584 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 486 548 1.6E-8 T 23-04-2016 DC74_RS23840 2e2b2c222a771ea0e2d2703618b312a0 584 Gene3D G3DSA:2.115.10.10 249 387 7.7E-10 T 23-04-2016 IPR023294 Tachylectin 2 DC74_RS23840 2e2b2c222a771ea0e2d2703618b312a0 584 Gene3D G3DSA:2.115.10.10 517 584 8.6E-9 T 23-04-2016 IPR023294 Tachylectin 2 DC74_RS23840 2e2b2c222a771ea0e2d2703618b312a0 584 Gene3D G3DSA:2.115.10.10 392 512 5.8E-11 T 23-04-2016 IPR023294 Tachylectin 2 DC74_RS23840 2e2b2c222a771ea0e2d2703618b312a0 584 Gene3D G3DSA:2.115.10.10 126 248 3.1E-13 T 23-04-2016 IPR023294 Tachylectin 2 DC74_RS23840 2e2b2c222a771ea0e2d2703618b312a0 584 SUPERFAMILY SSF69318 386 578 2.49E-22 T 23-04-2016 DC74_RS23840 2e2b2c222a771ea0e2d2703618b312a0 584 SUPERFAMILY SSF69318 84 400 2.75E-22 T 23-04-2016 DC74_RS07980 23d6f91fb10e2045ecf2924e6a2deec5 443 Gene3D G3DSA:1.10.10.10 14 84 1.3E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07980 23d6f91fb10e2045ecf2924e6a2deec5 443 SMART SM00345 15 74 3.8E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS07980 23d6f91fb10e2045ecf2924e6a2deec5 443 Gene3D G3DSA:3.40.640.10 128 324 3.7E-33 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS07980 23d6f91fb10e2045ecf2924e6a2deec5 443 Pfam PF00155 Aminotransferase class I and II 120 430 4.6E-21 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS07980 23d6f91fb10e2045ecf2924e6a2deec5 443 Gene3D G3DSA:3.90.1150.10 325 415 1.2E-4 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS07980 23d6f91fb10e2045ecf2924e6a2deec5 443 SUPERFAMILY SSF46785 12 78 4.4E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07980 23d6f91fb10e2045ecf2924e6a2deec5 443 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 8.0E-13 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS07980 23d6f91fb10e2045ecf2924e6a2deec5 443 PANTHER PTHR11751 78 432 9.5E-39 T 23-04-2016 DC74_RS07980 23d6f91fb10e2045ecf2924e6a2deec5 443 SUPERFAMILY SSF53383 70 433 5.85E-60 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS35020 de6f2eccdd70b3f92b1e164bb48379e5 405 SMART SM00331 142 389 4.7E-36 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS35020 de6f2eccdd70b3f92b1e164bb48379e5 405 SUPERFAMILY SSF81606 257 388 2.09E-8 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS35020 de6f2eccdd70b3f92b1e164bb48379e5 405 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 170 389 3.2E-39 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS35020 de6f2eccdd70b3f92b1e164bb48379e5 405 PANTHER PTHR21021 108 218 3.4E-31 T 23-04-2016 DC74_RS35020 de6f2eccdd70b3f92b1e164bb48379e5 405 PANTHER PTHR21021 252 398 3.4E-31 T 23-04-2016 DC74_RS00690 c5359e9d2706b77f8fcfc4115ccd0f97 213 Pfam PF00702 haloacid dehalogenase-like hydrolase 23 172 1.3E-11 T 23-04-2016 DC74_RS00690 c5359e9d2706b77f8fcfc4115ccd0f97 213 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 79 172 4.2E-7 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS00690 c5359e9d2706b77f8fcfc4115ccd0f97 213 PANTHER PTHR12725 1 207 6.9E-26 T 23-04-2016 DC74_RS00690 c5359e9d2706b77f8fcfc4115ccd0f97 213 SUPERFAMILY SSF56784 1 206 5.28E-35 T 23-04-2016 IPR023214 HAD-like domain DC74_RS00690 c5359e9d2706b77f8fcfc4115ccd0f97 213 Gene3D G3DSA:3.40.50.1000 1 206 3.1E-32 T 23-04-2016 IPR023214 HAD-like domain DC74_RS27985 455a3c0cb2aee6a0cfd78714f2d89a31 199 PIRSF PIRSF004553 1 187 4.0E-50 T 23-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 DC74_RS27985 455a3c0cb2aee6a0cfd78714f2d89a31 199 PANTHER PTHR18895 1 193 1.6E-35 T 23-04-2016 DC74_RS27985 455a3c0cb2aee6a0cfd78714f2d89a31 199 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 183 9.4E-44 T 23-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 DC74_RS27985 455a3c0cb2aee6a0cfd78714f2d89a31 199 Pfam PF03602 Conserved hypothetical protein 95 2 183 7.3E-52 T 23-04-2016 DC74_RS27985 455a3c0cb2aee6a0cfd78714f2d89a31 199 Gene3D G3DSA:3.40.50.150 1 186 2.5E-57 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS27985 455a3c0cb2aee6a0cfd78714f2d89a31 199 PANTHER PTHR18895:SF60 1 193 1.6E-35 T 23-04-2016 DC74_RS27985 455a3c0cb2aee6a0cfd78714f2d89a31 199 SUPERFAMILY SSF53335 2 181 6.66E-43 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS27985 455a3c0cb2aee6a0cfd78714f2d89a31 199 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 23-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 DC74_RS00910 a9d29d98a29db4a97827aa9b8422cc7d 150 Gene3D G3DSA:3.30.530.20 10 148 5.8E-11 T 23-04-2016 IPR023393 START-like domain DC74_RS00910 a9d29d98a29db4a97827aa9b8422cc7d 150 SUPERFAMILY SSF55961 9 149 3.59E-22 T 23-04-2016 DC74_RS00910 a9d29d98a29db4a97827aa9b8422cc7d 150 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 10 147 1.8E-10 T 23-04-2016 IPR019587 Polyketide cyclase/dehydrase DC74_RS29705 c626ce934bcbf148dd270ea2143a6218 319 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 219 281 1.2E-8 T 23-04-2016 DC74_RS29705 c626ce934bcbf148dd270ea2143a6218 319 SUPERFAMILY SSF69318 85 312 7.85E-20 T 23-04-2016 DC74_RS29705 c626ce934bcbf148dd270ea2143a6218 319 Gene3D G3DSA:2.115.10.10 128 272 2.1E-16 T 23-04-2016 IPR023294 Tachylectin 2 DC74_RS37755 497412fc812708cbd14cbf48f7ba4c9b 247 Pfam PF05139 Erythromycin esterase 18 238 1.1E-27 T 23-04-2016 IPR007815 Erythromycin esterase GO:0046677 DC74_RS37755 497412fc812708cbd14cbf48f7ba4c9b 247 SUPERFAMILY SSF159501 18 240 9.16E-25 T 23-04-2016 DC74_RS37755 497412fc812708cbd14cbf48f7ba4c9b 247 Gene3D G3DSA:3.40.1660.10 106 239 3.9E-11 T 23-04-2016 DC74_RS11430 abb232ecf85b300342d9f6d095359c08 251 PANTHER PTHR24319 1 250 2.9E-51 T 23-04-2016 DC74_RS11430 abb232ecf85b300342d9f6d095359c08 251 SUPERFAMILY SSF51735 1 247 3.3E-61 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11430 abb232ecf85b300342d9f6d095359c08 251 Gene3D G3DSA:3.40.50.720 1 246 1.5E-60 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11430 abb232ecf85b300342d9f6d095359c08 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.2E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11430 abb232ecf85b300342d9f6d095359c08 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.2E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11430 abb232ecf85b300342d9f6d095359c08 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.2E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11430 abb232ecf85b300342d9f6d095359c08 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.2E-18 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11430 abb232ecf85b300342d9f6d095359c08 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 159 0.001 T 23-04-2016 DC74_RS11430 abb232ecf85b300342d9f6d095359c08 251 PANTHER PTHR24319:SF23 1 250 2.9E-51 T 23-04-2016 DC74_RS11430 abb232ecf85b300342d9f6d095359c08 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 3.7E-43 T 23-04-2016 DC74_RS37350 cd879f861986f021252096d14df6bf7c 280 SUPERFAMILY SSF56300 3 258 6.33E-47 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS37350 cd879f861986f021252096d14df6bf7c 280 Pfam PF13277 YmdB-like protein 4 258 6.3E-60 T 23-04-2016 IPR005235 Metallophosphoesterase, YmdB-like DC74_RS37350 cd879f861986f021252096d14df6bf7c 280 Gene3D G3DSA:3.60.21.30 1 265 9.0E-67 T 23-04-2016 DC74_RS37350 cd879f861986f021252096d14df6bf7c 280 PANTHER PTHR36303 2 269 3.4E-56 T 23-04-2016 DC74_RS37350 cd879f861986f021252096d14df6bf7c 280 PANTHER PTHR36303:SF1 2 269 3.4E-56 T 23-04-2016 DC74_RS35355 19b0e5a395cedcf5a0b14645dcd3be63 439 PANTHER PTHR11662 6 211 2.6E-91 T 23-04-2016 DC74_RS35355 19b0e5a395cedcf5a0b14645dcd3be63 439 Gene3D G3DSA:1.20.1250.20 6 199 1.9E-36 T 23-04-2016 DC74_RS35355 19b0e5a395cedcf5a0b14645dcd3be63 439 PIRSF PIRSF002808 2 439 2.4E-64 T 23-04-2016 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 DC74_RS35355 19b0e5a395cedcf5a0b14645dcd3be63 439 PANTHER PTHR11662:SF141 6 211 2.6E-91 T 23-04-2016 DC74_RS35355 19b0e5a395cedcf5a0b14645dcd3be63 439 PANTHER PTHR11662:SF141 237 437 2.6E-91 T 23-04-2016 DC74_RS35355 19b0e5a395cedcf5a0b14645dcd3be63 439 SUPERFAMILY SSF103473 233 434 1.7E-48 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS35355 19b0e5a395cedcf5a0b14645dcd3be63 439 SUPERFAMILY SSF103473 6 200 1.7E-48 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS35355 19b0e5a395cedcf5a0b14645dcd3be63 439 PANTHER PTHR11662 237 437 2.6E-91 T 23-04-2016 DC74_RS35355 19b0e5a395cedcf5a0b14645dcd3be63 439 Gene3D G3DSA:1.20.1250.20 243 435 7.0E-24 T 23-04-2016 DC74_RS35355 19b0e5a395cedcf5a0b14645dcd3be63 439 Pfam PF07690 Major Facilitator Superfamily 16 399 4.9E-33 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS03945 e4887d773f35df4242e5cacbcd4c3f42 410 Pfam PF01494 FAD binding domain 4 332 1.1E-47 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS03945 e4887d773f35df4242e5cacbcd4c3f42 410 SUPERFAMILY SSF51905 5 178 2.43E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03945 e4887d773f35df4242e5cacbcd4c3f42 410 SUPERFAMILY SSF51905 270 360 2.43E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03945 e4887d773f35df4242e5cacbcd4c3f42 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 9.2E-18 T 23-04-2016 DC74_RS03945 e4887d773f35df4242e5cacbcd4c3f42 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 9.2E-18 T 23-04-2016 DC74_RS03945 e4887d773f35df4242e5cacbcd4c3f42 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 9.2E-18 T 23-04-2016 DC74_RS03945 e4887d773f35df4242e5cacbcd4c3f42 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 9.2E-18 T 23-04-2016 DC74_RS03945 e4887d773f35df4242e5cacbcd4c3f42 410 PANTHER PTHR13789:SF209 6 403 3.5E-133 T 23-04-2016 DC74_RS03945 e4887d773f35df4242e5cacbcd4c3f42 410 PANTHER PTHR13789 6 403 3.5E-133 T 23-04-2016 DC74_RS03945 e4887d773f35df4242e5cacbcd4c3f42 410 Gene3D G3DSA:3.50.50.60 271 350 6.2E-41 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03945 e4887d773f35df4242e5cacbcd4c3f42 410 Gene3D G3DSA:3.50.50.60 3 183 6.2E-41 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS07650 14403e3e40d251c78a0cf9c90e223658 390 PANTHER PTHR21661:SF35 3 380 4.1E-98 T 23-04-2016 DC74_RS07650 14403e3e40d251c78a0cf9c90e223658 390 PIRSF PIRSF001112 2 387 1.9E-110 T 23-04-2016 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9 DC74_RS07650 14403e3e40d251c78a0cf9c90e223658 390 SUPERFAMILY SSF53474 6 382 7.36E-93 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS07650 14403e3e40d251c78a0cf9c90e223658 390 Pfam PF06441 Epoxide hydrolase N terminus 8 120 7.6E-33 T 23-04-2016 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9 DC74_RS07650 14403e3e40d251c78a0cf9c90e223658 390 Gene3D G3DSA:3.40.50.1820 4 386 1.0E-132 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS07650 14403e3e40d251c78a0cf9c90e223658 390 PRINTS PR00412 Epoxide hydrolase signature 327 343 2.2E-12 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS07650 14403e3e40d251c78a0cf9c90e223658 390 PRINTS PR00412 Epoxide hydrolase signature 111 129 2.2E-12 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS07650 14403e3e40d251c78a0cf9c90e223658 390 PRINTS PR00412 Epoxide hydrolase signature 359 381 2.2E-12 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS07650 14403e3e40d251c78a0cf9c90e223658 390 PRINTS PR00412 Epoxide hydrolase signature 182 195 2.2E-12 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS07650 14403e3e40d251c78a0cf9c90e223658 390 PRINTS PR00412 Epoxide hydrolase signature 137 152 2.2E-12 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS07650 14403e3e40d251c78a0cf9c90e223658 390 PANTHER PTHR21661 3 380 4.1E-98 T 23-04-2016 DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 Pfam PF00364 Biotin-requiring enzyme 16 87 1.6E-22 T 23-04-2016 IPR000089 Biotin/lipoyl attachment DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 SUPERFAMILY SSF51230 13 105 5.1E-26 T 23-04-2016 IPR011053 Single hybrid motif DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 Gene3D G3DSA:4.10.320.10 188 235 1.9E-15 T 23-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 257 485 9.8E-78 T 23-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 PANTHER PTHR23151 8 143 1.6E-150 T 23-04-2016 DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 PANTHER PTHR23151 187 485 1.6E-150 T 23-04-2016 DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 Gene3D G3DSA:3.30.559.10 251 485 8.0E-83 T 23-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 39 68 - T 23-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 Gene3D G3DSA:2.40.50.100 12 103 7.7E-27 T 23-04-2016 DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 Pfam PF02817 e3 binding domain 190 224 1.6E-12 T 23-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 SUPERFAMILY SSF52777 247 485 1.33E-76 T 23-04-2016 DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 SUPERFAMILY SSF47005 185 228 3.01E-10 T 23-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 PANTHER PTHR23151:SF68 8 143 1.6E-150 T 23-04-2016 DC74_RS20345 5f2c6d26481bc6d09c9cd7634715acbd 488 PANTHER PTHR23151:SF68 187 485 1.6E-150 T 23-04-2016 DC74_RS39555 b43cf8189f0c70e3e648ae24f7ba9d7b 255 Pfam PF13349 Putative adhesin 119 249 1.7E-13 T 23-04-2016 IPR025164 Putative adhesin DC74_RS37065 d311d4254872b2e7dd3951b927b44865 182 Pfam PF03061 Thioesterase superfamily 18 97 5.4E-11 T 23-04-2016 IPR006683 Thioesterase domain DC74_RS37065 d311d4254872b2e7dd3951b927b44865 182 SUPERFAMILY SSF54637 6 134 2.06E-24 T 23-04-2016 IPR029069 HotDog domain DC74_RS37065 d311d4254872b2e7dd3951b927b44865 182 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 8 25 - T 23-04-2016 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 DC74_RS37065 d311d4254872b2e7dd3951b927b44865 182 Gene3D G3DSA:3.10.129.10 6 139 1.2E-25 T 23-04-2016 IPR029069 HotDog domain DC74_RS37065 d311d4254872b2e7dd3951b927b44865 182 PANTHER PTHR31793 5 148 1.2E-19 T 23-04-2016 DC74_RS15135 9ce87b98401cd151cc6c2274376c9a20 459 Pfam PF09594 Protein of unknown function (DUF2029) 84 336 1.3E-51 T 23-04-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 DC74_RS08460 b72b4532235c2fd559e7a661c612affc 304 PANTHER PTHR36151 3 304 5.5E-83 T 23-04-2016 DC74_RS08460 b72b4532235c2fd559e7a661c612affc 304 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 15 254 5.2E-46 T 23-04-2016 IPR018713 Domain of unknown function DUF2236 DC74_RS08460 b72b4532235c2fd559e7a661c612affc 304 PANTHER PTHR36151:SF3 3 304 5.5E-83 T 23-04-2016 DC74_RS02680 779456d02e990d60d329eac76309537e 397 Pfam PF07687 Peptidase dimerisation domain 190 281 4.7E-9 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS02680 779456d02e990d60d329eac76309537e 397 PANTHER PTHR11014:SF63 1 397 5.5E-123 T 23-04-2016 DC74_RS02680 779456d02e990d60d329eac76309537e 397 SUPERFAMILY SSF53187 3 200 1.48E-71 T 23-04-2016 DC74_RS02680 779456d02e990d60d329eac76309537e 397 SUPERFAMILY SSF53187 301 394 1.48E-71 T 23-04-2016 DC74_RS02680 779456d02e990d60d329eac76309537e 397 PIRSF PIRSF005962 1 397 4.3E-104 T 23-04-2016 IPR017439 Amidohydrolase GO:0016787 DC74_RS02680 779456d02e990d60d329eac76309537e 397 Gene3D G3DSA:3.30.70.360 184 300 2.0E-37 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS02680 779456d02e990d60d329eac76309537e 397 Pfam PF01546 Peptidase family M20/M25/M40 72 390 1.5E-31 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 DC74_RS02680 779456d02e990d60d329eac76309537e 397 SUPERFAMILY SSF55031 187 299 1.01E-28 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain DC74_RS02680 779456d02e990d60d329eac76309537e 397 Gene3D G3DSA:3.40.630.10 3 181 1.4E-86 T 23-04-2016 DC74_RS02680 779456d02e990d60d329eac76309537e 397 Gene3D G3DSA:3.40.630.10 301 394 1.4E-86 T 23-04-2016 DC74_RS02680 779456d02e990d60d329eac76309537e 397 PANTHER PTHR11014 1 397 5.5E-123 T 23-04-2016 DC74_RS02680 779456d02e990d60d329eac76309537e 397 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 379 5.1E-87 T 23-04-2016 IPR017439 Amidohydrolase GO:0016787 DC74_RS25225 a3c5029e18728971fd158ead1eebe0ba 154 Gene3D G3DSA:1.10.10.10 95 144 1.7E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS25225 a3c5029e18728971fd158ead1eebe0ba 154 Pfam PF04545 Sigma-70, region 4 95 143 3.6E-10 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS25225 a3c5029e18728971fd158ead1eebe0ba 154 SUPERFAMILY SSF88659 95 145 2.24E-11 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 PANTHER PTHR26402 3 221 7.0E-100 T 23-04-2016 DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 214 7.3E-20 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 SMART SM00421 157 214 3.5E-27 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 Gene3D G3DSA:1.10.10.10 127 221 1.9E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 9.2E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 9.2E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 9.2E-15 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 SUPERFAMILY SSF52172 2 138 6.26E-33 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 Gene3D G3DSA:3.40.50.2300 1 126 1.5E-36 T 23-04-2016 DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 PANTHER PTHR26402:SF564 3 221 7.0E-100 T 23-04-2016 DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 SMART SM00448 3 119 1.3E-32 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 Pfam PF00072 Response regulator receiver domain 5 120 8.3E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS22530 1c869a67d432882fc35d8369fadf6c0d 227 SUPERFAMILY SSF46894 149 220 1.87E-23 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS31835 5d76fbfa03fe19cfef0459520e6d65a2 560 SMART SM00642 29 427 4.0E-121 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS31835 5d76fbfa03fe19cfef0459520e6d65a2 560 Pfam PF00128 Alpha amylase, catalytic domain 44 400 1.2E-84 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DC74_RS31835 5d76fbfa03fe19cfef0459520e6d65a2 560 SUPERFAMILY SSF51445 19 489 2.19E-120 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS31835 5d76fbfa03fe19cfef0459520e6d65a2 560 PANTHER PTHR10357 16 432 5.6E-153 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS31835 5d76fbfa03fe19cfef0459520e6d65a2 560 PANTHER PTHR10357 468 519 5.6E-153 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 DC74_RS31835 5d76fbfa03fe19cfef0459520e6d65a2 560 Gene3D G3DSA:3.90.400.10 121 198 3.2E-26 T 23-04-2016 DC74_RS31835 5d76fbfa03fe19cfef0459520e6d65a2 560 Gene3D G3DSA:3.20.20.80 19 120 2.8E-104 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS31835 5d76fbfa03fe19cfef0459520e6d65a2 560 Gene3D G3DSA:3.20.20.80 199 490 2.8E-104 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS31835 5d76fbfa03fe19cfef0459520e6d65a2 560 Pfam PF11941 Domain of unknown function (DUF3459) 475 551 1.2E-8 T 23-04-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) DC74_RS31835 5d76fbfa03fe19cfef0459520e6d65a2 560 PANTHER PTHR10357:SF11 16 432 5.6E-153 T 23-04-2016 DC74_RS31835 5d76fbfa03fe19cfef0459520e6d65a2 560 PANTHER PTHR10357:SF11 468 519 5.6E-153 T 23-04-2016 DC74_RS25810 160f0e79921959e013dc1f5a1ae4c0c8 540 Gene3D G3DSA:3.90.76.10 47 203 1.8E-32 T 23-04-2016 DC74_RS25810 160f0e79921959e013dc1f5a1ae4c0c8 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 460 1.3E-48 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain DC74_RS25810 160f0e79921959e013dc1f5a1ae4c0c8 540 Gene3D G3DSA:3.10.105.10 320 511 2.3E-41 T 23-04-2016 DC74_RS25810 160f0e79921959e013dc1f5a1ae4c0c8 540 PANTHER PTHR30290:SF10 10 539 6.5E-114 T 23-04-2016 DC74_RS25810 160f0e79921959e013dc1f5a1ae4c0c8 540 SUPERFAMILY SSF53850 30 539 2.17E-90 T 23-04-2016 DC74_RS25810 160f0e79921959e013dc1f5a1ae4c0c8 540 Gene3D G3DSA:3.40.190.10 204 319 1.2E-24 T 23-04-2016 DC74_RS25810 160f0e79921959e013dc1f5a1ae4c0c8 540 PANTHER PTHR30290 10 539 6.5E-114 T 23-04-2016 DC74_RS25810 160f0e79921959e013dc1f5a1ae4c0c8 540 PIRSF PIRSF002741 5 537 3.7E-62 T 23-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DC74_RS17490 0ea8b5805ee4426e3587d6ae7550c4cc 476 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 386 421 7.7E-6 T 23-04-2016 IPR001451 Hexapeptide repeat DC74_RS17490 0ea8b5805ee4426e3587d6ae7550c4cc 476 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 444 37.009 T 23-04-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 DC74_RS17490 0ea8b5805ee4426e3587d6ae7550c4cc 476 PANTHER PTHR22572:SF115 1 441 3.4E-193 T 23-04-2016 DC74_RS17490 0ea8b5805ee4426e3587d6ae7550c4cc 476 SUPERFAMILY SSF51161 241 458 2.26E-42 T 23-04-2016 IPR011004 Trimeric LpxA-like DC74_RS17490 0ea8b5805ee4426e3587d6ae7550c4cc 476 SUPERFAMILY SSF53448 1 244 4.06E-51 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS17490 0ea8b5805ee4426e3587d6ae7550c4cc 476 Gene3D G3DSA:3.90.550.10 1 243 4.3E-63 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS17490 0ea8b5805ee4426e3587d6ae7550c4cc 476 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 446 1.5E-158 T 23-04-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 DC74_RS17490 0ea8b5805ee4426e3587d6ae7550c4cc 476 Gene3D G3DSA:2.160.10.10 248 430 8.0E-41 T 23-04-2016 DC74_RS17490 0ea8b5805ee4426e3587d6ae7550c4cc 476 Pfam PF00483 Nucleotidyl transferase 5 211 6.7E-16 T 23-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 DC74_RS17490 0ea8b5805ee4426e3587d6ae7550c4cc 476 PANTHER PTHR22572 1 441 3.4E-193 T 23-04-2016 DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 SUPERFAMILY SSF56801 10 568 1.83E-143 T 23-04-2016 DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 Pfam PF00501 AMP-binding enzyme 15 431 1.2E-96 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 Pfam PF13193 AMP-binding enzyme C-terminal domain 439 528 6.0E-7 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 Gene3D G3DSA:3.30.300.30 427 558 3.7E-26 T 23-04-2016 DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 Gene3D G3DSA:3.40.50.980 166 202 1.4E-42 T 23-04-2016 DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 Gene3D G3DSA:3.40.50.980 10 122 1.4E-42 T 23-04-2016 DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 36 454 4.0E-129 T 23-04-2016 IPR010071 Amino acid adenylation domain DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 Pfam PF00550 Phosphopantetheine attachment site 558 625 3.4E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 ProSitePatterns PS00455 Putative AMP-binding domain signature. 181 192 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 Gene3D G3DSA:1.10.1200.10 559 627 1.7E-17 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 Gene3D G3DSA:2.30.38.10 343 421 3.1E-28 T 23-04-2016 DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 PANTHER PTHR24095:SF137 11 625 1.6E-165 T 23-04-2016 DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 SUPERFAMILY SSF47336 550 627 1.31E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 Gene3D G3DSA:3.40.50.980 203 342 1.0E-35 T 23-04-2016 DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 ProSitePatterns PS00012 Phosphopantetheine attachment site. 583 598 - T 23-04-2016 IPR006162 Phosphopantetheine attachment site DC74_RS24645 196438939a2dc94d322c9c97bb0ed996 710 PANTHER PTHR24095 11 625 1.6E-165 T 23-04-2016 DC74_RS15725 3aea4b78e9ffc061167e0e909aecd7ef 491 PANTHER PTHR23500 39 479 9.8E-171 T 23-04-2016 DC74_RS15725 3aea4b78e9ffc061167e0e909aecd7ef 491 ProSitePatterns PS00216 Sugar transport proteins signature 1. 98 115 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS15725 3aea4b78e9ffc061167e0e909aecd7ef 491 ProSitePatterns PS00217 Sugar transport proteins signature 2. 140 165 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS15725 3aea4b78e9ffc061167e0e909aecd7ef 491 SUPERFAMILY SSF103473 25 475 7.32E-81 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS15725 3aea4b78e9ffc061167e0e909aecd7ef 491 PRINTS PR00171 Sugar transporter signature 401 413 2.2E-19 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS15725 3aea4b78e9ffc061167e0e909aecd7ef 491 PRINTS PR00171 Sugar transporter signature 290 300 2.2E-19 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS15725 3aea4b78e9ffc061167e0e909aecd7ef 491 PRINTS PR00171 Sugar transporter signature 52 62 2.2E-19 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS15725 3aea4b78e9ffc061167e0e909aecd7ef 491 PRINTS PR00171 Sugar transporter signature 135 154 2.2E-19 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS15725 3aea4b78e9ffc061167e0e909aecd7ef 491 Gene3D G3DSA:1.20.1250.20 277 478 1.4E-25 T 23-04-2016 DC74_RS15725 3aea4b78e9ffc061167e0e909aecd7ef 491 Gene3D G3DSA:1.20.1250.20 47 224 7.0E-28 T 23-04-2016 DC74_RS15725 3aea4b78e9ffc061167e0e909aecd7ef 491 Pfam PF00083 Sugar (and other) transporter 45 476 1.0E-112 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS15725 3aea4b78e9ffc061167e0e909aecd7ef 491 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 33 472 5.6E-117 T 23-04-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 Reactome: REACT_15518 DC74_RS06820 14d194d0dc50921dfed2924991f10634 396 PANTHER PTHR11712 18 396 6.4E-63 T 23-04-2016 DC74_RS06820 14d194d0dc50921dfed2924991f10634 396 SUPERFAMILY SSF48264 20 396 4.58E-73 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06820 14d194d0dc50921dfed2924991f10634 396 PRINTS PR00359 B-class P450 signature 287 314 1.1E-35 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06820 14d194d0dc50921dfed2924991f10634 396 PRINTS PR00359 B-class P450 signature 336 345 1.1E-35 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06820 14d194d0dc50921dfed2924991f10634 396 PRINTS PR00359 B-class P450 signature 269 280 1.1E-35 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06820 14d194d0dc50921dfed2924991f10634 396 PRINTS PR00359 B-class P450 signature 193 215 1.1E-35 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06820 14d194d0dc50921dfed2924991f10634 396 PRINTS PR00359 B-class P450 signature 315 330 1.1E-35 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06820 14d194d0dc50921dfed2924991f10634 396 PRINTS PR00359 B-class P450 signature 345 356 1.1E-35 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06820 14d194d0dc50921dfed2924991f10634 396 PRINTS PR00359 B-class P450 signature 140 156 1.1E-35 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06820 14d194d0dc50921dfed2924991f10634 396 PRINTS PR00359 B-class P450 signature 157 172 1.1E-35 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06820 14d194d0dc50921dfed2924991f10634 396 Pfam PF00067 Cytochrome P450 217 365 8.0E-15 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06820 14d194d0dc50921dfed2924991f10634 396 Gene3D G3DSA:1.10.630.10 20 396 5.9E-96 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS20600 ae64cc1dd320a7d1f976897746987025 256 PANTHER PTHR37313:SF2 20 256 3.3E-78 T 23-04-2016 DC74_RS20600 ae64cc1dd320a7d1f976897746987025 256 Pfam PF05949 Bacterial protein of unknown function (DUF881) 98 252 2.4E-43 T 23-04-2016 IPR010273 Protein of unknown function DUF881 DC74_RS20600 ae64cc1dd320a7d1f976897746987025 256 PANTHER PTHR37313 20 256 3.3E-78 T 23-04-2016 DC74_RS08080 96accd1363ba68c81161b8c42d2f945e 127 SUPERFAMILY SSF50346 6 108 9.89E-23 T 23-04-2016 IPR011033 PRC-barrel-like DC74_RS08080 96accd1363ba68c81161b8c42d2f945e 127 Gene3D G3DSA:2.30.30.240 8 64 2.5E-5 T 23-04-2016 DC74_RS08080 96accd1363ba68c81161b8c42d2f945e 127 Pfam PF05239 PRC-barrel domain 8 73 1.0E-10 T 23-04-2016 IPR027275 PRC-barrel domain DC74_RS28345 80376e63293d3c9e9612e2abf7bf8399 239 Pfam PF14016 Protein of unknown function (DUF4232) 100 219 1.8E-16 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS26875 879d2354ee3d0c34c18407fd42611f15 74 PRINTS PR01249 Ribosomal protein L31 signature 47 65 1.3E-20 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS26875 879d2354ee3d0c34c18407fd42611f15 74 PRINTS PR01249 Ribosomal protein L31 signature 32 47 1.3E-20 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS26875 879d2354ee3d0c34c18407fd42611f15 74 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.3E-20 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS26875 879d2354ee3d0c34c18407fd42611f15 74 PANTHER PTHR33280 2 72 4.0E-32 T 23-04-2016 DC74_RS26875 879d2354ee3d0c34c18407fd42611f15 74 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 67 3.8E-33 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS26875 879d2354ee3d0c34c18407fd42611f15 74 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS26875 879d2354ee3d0c34c18407fd42611f15 74 SUPERFAMILY SSF143800 1 66 9.42E-25 T 23-04-2016 DC74_RS26875 879d2354ee3d0c34c18407fd42611f15 74 Pfam PF01197 Ribosomal protein L31 2 66 4.3E-30 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS26875 879d2354ee3d0c34c18407fd42611f15 74 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 29.01 T 23-04-2016 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS12405 bed4fae3ee43cc334cebe0acb3e8e0eb 245 PANTHER PTHR23327:SF0 4 232 1.1E-15 T 23-04-2016 DC74_RS12405 bed4fae3ee43cc334cebe0acb3e8e0eb 245 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 221 2.5E-27 T 23-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 DC74_RS12405 bed4fae3ee43cc334cebe0acb3e8e0eb 245 SMART SM00464 5 221 1.8E-40 T 23-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 DC74_RS12405 bed4fae3ee43cc334cebe0acb3e8e0eb 245 PANTHER PTHR23327 4 232 1.1E-15 T 23-04-2016 DC74_RS12405 bed4fae3ee43cc334cebe0acb3e8e0eb 245 SUPERFAMILY SSF88697 5 220 4.47E-37 T 23-04-2016 IPR015947 PUA-like domain DC74_RS12035 85db7789340a3b128cf63a934d1563f9 315 PANTHER PTHR42301 1 312 2.0E-178 T 23-04-2016 DC74_RS12035 85db7789340a3b128cf63a934d1563f9 315 PANTHER PTHR42301:SF1 1 312 2.0E-178 T 23-04-2016 DC74_RS12035 85db7789340a3b128cf63a934d1563f9 315 PIRSF PIRSF028754 13 315 2.3E-105 T 23-04-2016 IPR008492 Protein of unknown function DUF774 DC74_RS12035 85db7789340a3b128cf63a934d1563f9 315 Gene3D G3DSA:1.10.287.100 237 275 2.3E-7 T 23-04-2016 IPR013028 Transcription factor IIA, alpha subunit, N-terminal GO:0006367 DC74_RS12035 85db7789340a3b128cf63a934d1563f9 315 Pfam PF09754 PAC2 family 35 253 1.2E-36 T 23-04-2016 IPR019151 Proteasome assembly chaperone 2 DC74_RS12035 85db7789340a3b128cf63a934d1563f9 315 SUPERFAMILY SSF159659 24 277 7.98E-72 T 23-04-2016 DC74_RS16775 eb962fb21584bfb12a678dc830c35191 899 Pfam PF09586 Bacterial membrane protein YfhO 46 562 2.0E-48 T 23-04-2016 IPR018580 Uncharacterised protein family YfhO DC74_RS16775 eb962fb21584bfb12a678dc830c35191 899 PANTHER PTHR38454:SF1 27 889 2.2E-45 T 23-04-2016 DC74_RS16775 eb962fb21584bfb12a678dc830c35191 899 PANTHER PTHR38454 27 889 2.2E-45 T 23-04-2016 DC74_RS26385 cd9353e421963debfde3000afdcd3e2a 332 SUPERFAMILY SSF48452 19 109 1.34E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS26385 cd9353e421963debfde3000afdcd3e2a 332 Gene3D G3DSA:1.25.40.10 21 110 9.8E-10 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 PANTHER PTHR23501 14 503 1.1E-121 T 23-04-2016 DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 2.9E-8 T 23-04-2016 DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 2.9E-8 T 23-04-2016 DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 PRINTS PR01036 Tetracycline resistance protein TetB signature 212 230 2.9E-8 T 23-04-2016 DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 PRINTS PR01036 Tetracycline resistance protein TetB signature 116 136 2.9E-8 T 23-04-2016 DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 Pfam PF07690 Major Facilitator Superfamily 27 418 5.4E-61 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 ProSitePatterns PS00216 Sugar transport proteins signature 1. 76 93 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 Gene3D G3DSA:1.20.1250.20 485 512 3.8E-28 T 23-04-2016 DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 Gene3D G3DSA:1.20.1250.20 272 429 3.8E-28 T 23-04-2016 DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 497 2.1E-70 T 23-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 SUPERFAMILY SSF103473 257 428 4.62E-76 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 SUPERFAMILY SSF103473 13 205 4.62E-76 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 SUPERFAMILY SSF103473 484 508 4.62E-76 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS36210 71fdca2335125ebc83540f42049d741b 516 Gene3D G3DSA:1.20.1250.20 16 204 2.1E-40 T 23-04-2016 DC74_RS23500 ee359ce3c6f1931766fe10880d6523ee 83 Pfam PF11662 Protein of unknown function (DUF3263) 12 83 1.0E-33 T 23-04-2016 IPR021678 Protein of unknown function DUF3263 DC74_RS14035 5bc4dca0dc663b7a9ae9198db2ffc439 348 Gene3D G3DSA:3.40.47.10 219 345 9.4E-47 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS14035 5bc4dca0dc663b7a9ae9198db2ffc439 348 Gene3D G3DSA:3.40.47.10 13 181 3.2E-55 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS14035 5bc4dca0dc663b7a9ae9198db2ffc439 348 SUPERFAMILY SSF53901 11 346 8.46E-63 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS14035 5bc4dca0dc663b7a9ae9198db2ffc439 348 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 12 347 60.768 T 23-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS14035 5bc4dca0dc663b7a9ae9198db2ffc439 348 PANTHER PTHR18919 37 348 3.8E-181 T 23-04-2016 DC74_RS14035 5bc4dca0dc663b7a9ae9198db2ffc439 348 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 13 346 4.3E-108 T 23-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS14035 5bc4dca0dc663b7a9ae9198db2ffc439 348 PANTHER PTHR18919:SF103 37 348 3.8E-181 T 23-04-2016 DC74_RS14035 5bc4dca0dc663b7a9ae9198db2ffc439 348 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 257 346 3.8E-31 T 23-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS14035 5bc4dca0dc663b7a9ae9198db2ffc439 348 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 117 194 3.5E-25 T 23-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 DC74_RS35410 e8d13b8436ac9f2cbea37f6387ab07dd 148 Pfam PF13581 Histidine kinase-like ATPase domain 12 114 1.1E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35410 e8d13b8436ac9f2cbea37f6387ab07dd 148 SUPERFAMILY SSF55874 23 137 2.54E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35410 e8d13b8436ac9f2cbea37f6387ab07dd 148 Gene3D G3DSA:3.30.565.10 13 137 2.0E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS24520 6c5093381cd6b00414a5f37a38db3b85 615 PANTHER PTHR35861:SF1 323 614 8.7E-99 T 23-04-2016 DC74_RS24520 6c5093381cd6b00414a5f37a38db3b85 615 PANTHER PTHR35861:SF1 6 283 8.7E-99 T 23-04-2016 DC74_RS24520 6c5093381cd6b00414a5f37a38db3b85 615 Pfam PF04984 Phage tail sheath protein 5 130 7.7E-17 T 23-04-2016 IPR007067 Tail sheath protein DC74_RS24520 6c5093381cd6b00414a5f37a38db3b85 615 Pfam PF04984 Phage tail sheath protein 338 607 3.2E-32 T 23-04-2016 IPR007067 Tail sheath protein DC74_RS24520 6c5093381cd6b00414a5f37a38db3b85 615 PANTHER PTHR35861 323 614 8.7E-99 T 23-04-2016 DC74_RS24520 6c5093381cd6b00414a5f37a38db3b85 615 PANTHER PTHR35861 6 283 8.7E-99 T 23-04-2016 DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 SUPERFAMILY SSF48498 78 206 2.89E-26 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 75 203 4.5E-13 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 PANTHER PTHR30055 1 126 3.7E-33 T 23-04-2016 DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 PRINTS PR00400 Tetracycline repressor protein signature 79 98 1.2E-14 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 PRINTS PR00400 Tetracycline repressor protein signature 26 49 1.2E-14 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 PRINTS PR00400 Tetracycline repressor protein signature 188 202 1.2E-14 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 PRINTS PR00400 Tetracycline repressor protein signature 135 154 1.2E-14 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.9E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.9E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 PANTHER PTHR30055:SF36 1 126 3.7E-33 T 23-04-2016 DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 5.7E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 SUPERFAMILY SSF46689 2 67 6.48E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS10705 0adaf4c8f6bf0131b0c1caf3b9665123 220 Gene3D G3DSA:1.10.357.10 2 206 5.5E-62 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS13090 c2a00d3256a5bef1de139a4ba4d66719 297 PANTHER PTHR11092:SF0 1 295 2.6E-128 T 23-04-2016 DC74_RS13090 c2a00d3256a5bef1de139a4ba4d66719 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 127 3.8E-12 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS13090 c2a00d3256a5bef1de139a4ba4d66719 297 Gene3D G3DSA:3.40.50.720 1 235 1.2E-26 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS13090 c2a00d3256a5bef1de139a4ba4d66719 297 PANTHER PTHR11092 1 295 2.6E-128 T 23-04-2016 IPR010099 Epimerase family protein SDR39U1 DC74_RS13090 c2a00d3256a5bef1de139a4ba4d66719 297 SUPERFAMILY SSF51735 1 281 2.61E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS13090 c2a00d3256a5bef1de139a4ba4d66719 297 Pfam PF08338 Domain of unknown function (DUF1731) 248 293 1.8E-16 T 23-04-2016 IPR013549 Domain of unknown function DUF1731 DC74_RS13090 c2a00d3256a5bef1de139a4ba4d66719 297 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 291 6.9E-98 T 23-04-2016 IPR010099 Epimerase family protein SDR39U1 DC74_RS29870 0607f9872ae9d3b974a16597ec1eed41 281 Gene3D G3DSA:3.40.430.10 60 280 9.9E-59 T 23-04-2016 IPR024072 Dihydrofolate reductase-like domain DC74_RS29870 0607f9872ae9d3b974a16597ec1eed41 281 Pfam PF01872 RibD C-terminal domain 64 257 8.0E-27 T 23-04-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 DC74_RS29870 0607f9872ae9d3b974a16597ec1eed41 281 SUPERFAMILY SSF53597 64 280 2.3E-36 T 23-04-2016 IPR024072 Dihydrofolate reductase-like domain DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 PIRSF PIRSF000349 1 208 6.8E-71 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 PANTHER PTHR11404:SF27 1 211 3.1E-150 T 23-04-2016 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 SUPERFAMILY SSF54719 98 205 8.51E-38 T 23-04-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 83 5.4E-29 T 23-04-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 3.4E-18 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 3.4E-18 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 3.4E-18 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 3.4E-18 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 3.4E-18 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 PANTHER PTHR11404 1 211 3.1E-150 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 198 1.2E-32 T 23-04-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 SUPERFAMILY SSF46609 2 89 7.07E-30 T 23-04-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 23-04-2016 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 DC74_RS15400 353cc4f5236b9ccad4002952a4d44f67 213 Gene3D G3DSA:1.10.287.990 22 84 1.1E-21 T 23-04-2016 DC74_RS33720 862efc84cb1ecfe5b1774509630755c6 425 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 4 413 30.71 T 23-04-2016 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA01014 DC74_RS33720 862efc84cb1ecfe5b1774509630755c6 425 SUPERFAMILY SSF55931 282 320 8.44E-36 T 23-04-2016 DC74_RS33720 862efc84cb1ecfe5b1774509630755c6 425 SUPERFAMILY SSF55931 21 246 8.44E-36 T 23-04-2016 DC74_RS33720 862efc84cb1ecfe5b1774509630755c6 425 PIRSF PIRSF017901 4 408 5.3E-108 T 23-04-2016 DC74_RS33720 862efc84cb1ecfe5b1774509630755c6 425 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 16 375 1.9E-126 T 23-04-2016 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA01014 DC74_RS33720 862efc84cb1ecfe5b1774509630755c6 425 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 29 333 1.2E-74 T 23-04-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 DC74_RS33720 862efc84cb1ecfe5b1774509630755c6 425 PANTHER PTHR34378:SF2 4 377 9.1E-130 T 23-04-2016 DC74_RS33720 862efc84cb1ecfe5b1774509630755c6 425 PANTHER PTHR34378 4 377 9.1E-130 T 23-04-2016 DC74_RS27130 06781dce9cdeb0e90f391879576c043a 257 Pfam PF12730 ABC-2 family transporter protein 8 188 4.8E-7 T 23-04-2016 IPR032688 ABC-2 family transporter protein GO:0006810 DC74_RS22240 8898cebbf9b7d67524001d43b28f9b18 152 SUPERFAMILY SSF55298 19 146 3.77E-28 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS22240 8898cebbf9b7d67524001d43b28f9b18 152 PANTHER PTHR11803 15 146 4.4E-26 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS22240 8898cebbf9b7d67524001d43b28f9b18 152 Pfam PF01042 Endoribonuclease L-PSP 24 144 2.1E-20 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family DC74_RS22240 8898cebbf9b7d67524001d43b28f9b18 152 Gene3D G3DSA:3.30.1330.40 16 145 6.2E-30 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS38170 5791ae0915265d3a120baf5a159b193b 313 SUPERFAMILY SSF103481 205 301 2.35E-9 T 23-04-2016 DC74_RS38170 5791ae0915265d3a120baf5a159b193b 313 Pfam PF00892 EamA-like transporter family 19 148 4.6E-8 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS38170 5791ae0915265d3a120baf5a159b193b 313 Pfam PF00892 EamA-like transporter family 164 293 2.5E-9 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS38170 5791ae0915265d3a120baf5a159b193b 313 PANTHER PTHR12715 6 303 1.9E-20 T 23-04-2016 DC74_RS38170 5791ae0915265d3a120baf5a159b193b 313 SUPERFAMILY SSF103481 50 149 3.53E-8 T 23-04-2016 DC74_RS39235 f4c45447a7d8002610c394a81c99c565 115 SUPERFAMILY SSF54909 1 95 8.04E-25 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS39235 f4c45447a7d8002610c394a81c99c565 115 Pfam PF07045 Domain of unknown function (DUF1330) 2 95 4.2E-26 T 23-04-2016 IPR010753 Domain of unknown function DUF1330 DC74_RS39235 f4c45447a7d8002610c394a81c99c565 115 Gene3D G3DSA:3.30.70.900 1 96 3.7E-30 T 23-04-2016 DC74_RS39235 f4c45447a7d8002610c394a81c99c565 115 PANTHER PTHR41521 1 102 7.2E-14 T 23-04-2016 DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 Gene3D G3DSA:3.40.50.1820 65 150 1.9E-54 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 Gene3D G3DSA:3.40.50.1820 378 499 1.9E-54 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 Gene3D G3DSA:3.40.50.1820 194 323 1.9E-54 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 PANTHER PTHR10992:SF107 196 282 1.9E-35 T 23-04-2016 DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 PANTHER PTHR10992:SF107 382 500 1.9E-35 T 23-04-2016 DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 PANTHER PTHR10992:SF107 50 149 1.9E-35 T 23-04-2016 DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 PANTHER PTHR10992 196 282 1.9E-35 T 23-04-2016 DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 PANTHER PTHR10992 382 500 1.9E-35 T 23-04-2016 DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 PANTHER PTHR10992 50 149 1.9E-35 T 23-04-2016 DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 SUPERFAMILY SSF53474 319 483 9.1E-25 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 SUPERFAMILY SSF53474 84 145 9.1E-25 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 SUPERFAMILY SSF53474 185 249 9.1E-25 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS20045 68f090b2c7dede9a027dd193b013326a 512 Pfam PF08386 TAP-like protein 417 510 1.6E-26 T 23-04-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal DC74_RS31790 e48b7e2d8ea988eda07c0c41f7743751 211 Pfam PF03130 PBS lyase HEAT-like repeat 157 180 3.2E-4 T 23-04-2016 IPR004155 PBS lyase HEAT-like repeat DC74_RS31790 e48b7e2d8ea988eda07c0c41f7743751 211 SUPERFAMILY SSF48371 17 197 2.76E-10 T 23-04-2016 IPR016024 Armadillo-type fold GO:0005488 DC74_RS31790 e48b7e2d8ea988eda07c0c41f7743751 211 Gene3D G3DSA:1.25.10.10 134 197 3.6E-12 T 23-04-2016 IPR011989 Armadillo-like helical DC74_RS31790 e48b7e2d8ea988eda07c0c41f7743751 211 Gene3D G3DSA:1.25.10.10 57 101 3.6E-12 T 23-04-2016 IPR011989 Armadillo-like helical DC74_RS31790 e48b7e2d8ea988eda07c0c41f7743751 211 SMART SM00567 E-Z type HEAT repeats 85 114 120.0 T 23-04-2016 IPR004155 PBS lyase HEAT-like repeat DC74_RS31790 e48b7e2d8ea988eda07c0c41f7743751 211 SMART SM00567 E-Z type HEAT repeats 154 183 0.031 T 23-04-2016 IPR004155 PBS lyase HEAT-like repeat DC74_RS31790 e48b7e2d8ea988eda07c0c41f7743751 211 SMART SM00567 E-Z type HEAT repeats 54 83 82.0 T 23-04-2016 IPR004155 PBS lyase HEAT-like repeat DC74_RS19455 2783f5b182c5ecc0460b9558bd6fc6f8 92 Pfam PF05768 Glutaredoxin-like domain (DUF836) 18 90 7.3E-20 T 23-04-2016 IPR008554 Glutaredoxin-like DC74_RS19455 2783f5b182c5ecc0460b9558bd6fc6f8 92 Gene3D G3DSA:3.40.30.10 18 91 1.1E-26 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS19455 2783f5b182c5ecc0460b9558bd6fc6f8 92 SUPERFAMILY SSF52833 15 91 2.5E-17 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS30040 d46cababe5435e63ae6deea1f3533fe9 342 Gene3D G3DSA:3.40.1350.10 17 77 6.5E-5 T 23-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 DC74_RS30040 d46cababe5435e63ae6deea1f3533fe9 342 Pfam PF04471 Restriction endonuclease 16 96 8.3E-6 T 23-04-2016 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 DC74_RS03465 ed0f777e42f703d53cbff03a07c44e24 479 PIRSF PIRSF001386 15 473 3.0E-194 T 23-04-2016 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1|UniPathway: UPA00332 DC74_RS03465 ed0f777e42f703d53cbff03a07c44e24 479 Gene3D G3DSA:3.90.1150.10 312 471 4.2E-57 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS03465 ed0f777e42f703d53cbff03a07c44e24 479 SUPERFAMILY SSF53383 18 471 1.22E-126 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS03465 ed0f777e42f703d53cbff03a07c44e24 479 PANTHER PTHR32325 13 477 2.1E-179 T 23-04-2016 DC74_RS03465 ed0f777e42f703d53cbff03a07c44e24 479 Pfam PF01212 Beta-eliminating lyase 61 437 8.1E-88 T 23-04-2016 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 DC74_RS03465 ed0f777e42f703d53cbff03a07c44e24 479 Gene3D G3DSA:3.40.640.10 73 311 4.0E-80 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS38510 2981b8f62fc2656df18e5f98ce16fa9e 381 Gene3D G3DSA:3.75.10.10 40 376 2.8E-117 T 23-04-2016 DC74_RS38510 2981b8f62fc2656df18e5f98ce16fa9e 381 SUPERFAMILY SSF55909 42 376 1.14E-106 T 23-04-2016 DC74_RS38510 2981b8f62fc2656df18e5f98ce16fa9e 381 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 49 376 2.1E-105 T 23-04-2016 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 DC74_RS38510 2981b8f62fc2656df18e5f98ce16fa9e 381 PANTHER PTHR31377 31 376 1.6E-105 T 23-04-2016 DC74_RS38510 2981b8f62fc2656df18e5f98ce16fa9e 381 PANTHER PTHR31377:SF0 31 376 1.6E-105 T 23-04-2016 DC74_RS01015 30eb8d26490c81486ec09c52b868cbf4 249 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 23 219 3.8E-14 T 23-04-2016 IPR018713 Domain of unknown function DUF2236 DC74_RS01015 30eb8d26490c81486ec09c52b868cbf4 249 PANTHER PTHR36124 6 222 4.2E-39 T 23-04-2016 DC74_RS20495 58a8a867a2e603463dc7d997a983d3ec 109 SUPERFAMILY SSF52821 12 102 2.36E-28 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS20495 58a8a867a2e603463dc7d997a983d3ec 109 SMART SM00450 4 97 5.6E-16 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS20495 58a8a867a2e603463dc7d997a983d3ec 109 Gene3D G3DSA:3.40.250.10 14 101 3.5E-27 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS20495 58a8a867a2e603463dc7d997a983d3ec 109 Pfam PF00581 Rhodanese-like domain 13 93 1.6E-12 T 23-04-2016 IPR001763 Rhodanese-like domain DC74_RS21085 52931521060df85c2801d4edbc4fab47 288 SUPERFAMILY SSF55920 17 262 2.22E-25 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS21085 52931521060df85c2801d4edbc4fab47 288 PANTHER PTHR10804:SF92 18 167 1.9E-79 T 23-04-2016 DC74_RS21085 52931521060df85c2801d4edbc4fab47 288 Pfam PF00557 Metallopeptidase family M24 21 261 8.0E-29 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS21085 52931521060df85c2801d4edbc4fab47 288 PANTHER PTHR10804 18 167 1.9E-79 T 23-04-2016 DC74_RS21085 52931521060df85c2801d4edbc4fab47 288 Gene3D G3DSA:3.90.230.10 17 262 1.2E-26 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS19900 d1d5ad0009e4d385893dbe974565e90e 555 SUPERFAMILY SSF103473 15 198 8.24E-6 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS19900 d1d5ad0009e4d385893dbe974565e90e 555 Gene3D G3DSA:3.40.50.150 295 516 1.5E-54 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS19900 d1d5ad0009e4d385893dbe974565e90e 555 Pfam PF01564 Spermine/spermidine synthase 282 456 7.6E-27 T 23-04-2016 DC74_RS19900 d1d5ad0009e4d385893dbe974565e90e 555 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 193 537 18.968 T 23-04-2016 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 DC74_RS19900 d1d5ad0009e4d385893dbe974565e90e 555 SUPERFAMILY SSF53335 281 466 2.91E-44 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS19900 d1d5ad0009e4d385893dbe974565e90e 555 PANTHER PTHR11558 282 465 3.4E-52 T 23-04-2016 DC74_RS19900 d1d5ad0009e4d385893dbe974565e90e 555 PANTHER PTHR11558:SF26 282 465 3.4E-52 T 23-04-2016 DC74_RS19900 d1d5ad0009e4d385893dbe974565e90e 555 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 315 328 - T 23-04-2016 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 DC74_RS18695 1e3184771b99407e78978da36925189b 74 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 1.4E-22 T 23-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18695 1e3184771b99407e78978da36925189b 74 SUPERFAMILY SSF46561 5 67 4.97E-24 T 23-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18695 1e3184771b99407e78978da36925189b 74 Gene3D G3DSA:1.10.287.310 6 69 1.2E-31 T 23-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18695 1e3184771b99407e78978da36925189b 74 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 23-04-2016 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18695 1e3184771b99407e78978da36925189b 74 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 17.977 T 23-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18695 1e3184771b99407e78978da36925189b 74 PANTHER PTHR10916:SF0 6 66 1.0E-26 T 23-04-2016 DC74_RS18695 1e3184771b99407e78978da36925189b 74 PANTHER PTHR10916 6 66 1.0E-26 T 23-04-2016 DC74_RS18695 1e3184771b99407e78978da36925189b 74 Pfam PF00831 Ribosomal L29 protein 9 64 4.9E-26 T 23-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS09130 e991204cbe544f2165cd8d45a7ff2e25 402 PANTHER PTHR10314:SF5 37 385 3.3E-24 T 23-04-2016 DC74_RS09130 e991204cbe544f2165cd8d45a7ff2e25 402 Gene3D G3DSA:3.40.50.1100 117 193 4.2E-6 T 23-04-2016 DC74_RS09130 e991204cbe544f2165cd8d45a7ff2e25 402 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 80 385 8.0E-40 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS09130 e991204cbe544f2165cd8d45a7ff2e25 402 Gene3D G3DSA:3.40.50.1100 194 388 2.7E-27 T 23-04-2016 DC74_RS09130 e991204cbe544f2165cd8d45a7ff2e25 402 SUPERFAMILY SSF53686 63 388 2.62E-47 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS09130 e991204cbe544f2165cd8d45a7ff2e25 402 PANTHER PTHR10314 37 385 3.3E-24 T 23-04-2016 DC74_RS26770 bea214dd0fb0146b7eee016d784587c5 246 PANTHER PTHR30328 4 188 1.2E-27 T 23-04-2016 DC74_RS26770 bea214dd0fb0146b7eee016d784587c5 246 PANTHER PTHR30328:SF24 4 188 1.2E-27 T 23-04-2016 DC74_RS26770 bea214dd0fb0146b7eee016d784587c5 246 Gene3D G3DSA:1.10.357.10 11 215 8.2E-33 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS26770 bea214dd0fb0146b7eee016d784587c5 246 SUPERFAMILY SSF46689 15 88 5.08E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS26770 bea214dd0fb0146b7eee016d784587c5 246 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 74 3.3E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS24390 bc96503cfeab94f25b951c531e7eedd7 495 Pfam PF04434 SWIM zinc finger 75 92 3.3E-4 T 23-04-2016 IPR007527 Zinc finger, SWIM-type GO:0008270 DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 PANTHER PTHR33841:SF2 498 556 8.5E-29 T 23-04-2016 DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 PANTHER PTHR33841:SF2 622 776 8.5E-29 T 23-04-2016 DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 Gene3D G3DSA:3.40.50.150 1181 1215 3.6E-23 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 Gene3D G3DSA:3.40.50.150 1279 1337 3.6E-23 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 Gene3D G3DSA:3.40.50.150 617 750 3.6E-23 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 SUPERFAMILY SSF53335 1274 1335 4.28E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 SUPERFAMILY SSF53335 351 374 4.28E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 SUPERFAMILY SSF53335 458 472 4.28E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 SUPERFAMILY SSF53335 1193 1219 4.28E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 SUPERFAMILY SSF53335 499 547 4.28E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 SUPERFAMILY SSF53335 618 772 4.28E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 1204 1210 - T 23-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 PANTHER PTHR33841 498 556 8.5E-29 T 23-04-2016 DC74_RS40490 53c35f325ddf241dceb293be83b73a6f 1886 PANTHER PTHR33841 622 776 8.5E-29 T 23-04-2016 DC74_RS21390 79a113b10a42368c0d6c2ce1b440c0b2 240 PANTHER PTHR26402 8 132 1.8E-39 T 23-04-2016 DC74_RS21390 79a113b10a42368c0d6c2ce1b440c0b2 240 SUPERFAMILY SSF52172 8 145 2.28E-33 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS21390 79a113b10a42368c0d6c2ce1b440c0b2 240 SMART SM00448 8 122 1.5E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS21390 79a113b10a42368c0d6c2ce1b440c0b2 240 Gene3D G3DSA:3.40.50.2300 7 140 2.8E-31 T 23-04-2016 DC74_RS21390 79a113b10a42368c0d6c2ce1b440c0b2 240 Pfam PF00072 Response regulator receiver domain 10 122 4.6E-23 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS21390 79a113b10a42368c0d6c2ce1b440c0b2 240 PANTHER PTHR26402:SF563 8 132 1.8E-39 T 23-04-2016 DC74_RS21965 cacdc0368fa0846befbbc41a835d8236 274 Pfam PF02104 SURF1 family 20 235 1.1E-21 T 23-04-2016 IPR002994 Surfeit locus 1/Shy1 GO:0016020 DC74_RS39745 bbf830ee1cb830443a64661339447f47 448 SUPERFAMILY SSF56024 287 430 1.45E-9 T 23-04-2016 DC74_RS39745 bbf830ee1cb830443a64661339447f47 448 Gene3D G3DSA:3.30.870.10 62 192 6.1E-11 T 23-04-2016 DC74_RS39745 bbf830ee1cb830443a64661339447f47 448 Gene3D G3DSA:3.30.870.10 290 430 4.3E-10 T 23-04-2016 DC74_RS39745 bbf830ee1cb830443a64661339447f47 448 Pfam PF13091 PLD-like domain 290 427 5.1E-9 T 23-04-2016 IPR025202 Phospholipase D-like domain DC74_RS39745 bbf830ee1cb830443a64661339447f47 448 Pfam PF13091 PLD-like domain 81 192 1.5E-8 T 23-04-2016 IPR025202 Phospholipase D-like domain DC74_RS39745 bbf830ee1cb830443a64661339447f47 448 SUPERFAMILY SSF56024 63 192 2.18E-9 T 23-04-2016 DC74_RS22085 20fa326589e3b4b3591138bb57b8d97f 653 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 31 83 3.1E-21 T 23-04-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 DC74_RS22085 20fa326589e3b4b3591138bb57b8d97f 653 Pfam PF00501 AMP-binding enzyme 89 525 2.0E-92 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS22085 20fa326589e3b4b3591138bb57b8d97f 653 Gene3D G3DSA:3.30.300.30 522 642 2.4E-30 T 23-04-2016 DC74_RS22085 20fa326589e3b4b3591138bb57b8d97f 653 Gene3D G3DSA:2.30.38.10 443 518 7.5E-8 T 23-04-2016 DC74_RS22085 20fa326589e3b4b3591138bb57b8d97f 653 Gene3D G3DSA:3.40.50.980 81 268 7.0E-42 T 23-04-2016 DC74_RS22085 20fa326589e3b4b3591138bb57b8d97f 653 SUPERFAMILY SSF56801 31 644 7.98E-178 T 23-04-2016 DC74_RS22085 20fa326589e3b4b3591138bb57b8d97f 653 Gene3D G3DSA:3.40.50.980 269 427 1.2E-26 T 23-04-2016 DC74_RS22085 20fa326589e3b4b3591138bb57b8d97f 653 Pfam PF13193 AMP-binding enzyme C-terminal domain 534 612 4.5E-27 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain DC74_RS22085 20fa326589e3b4b3591138bb57b8d97f 653 ProSitePatterns PS00455 Putative AMP-binding domain signature. 263 274 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS22085 20fa326589e3b4b3591138bb57b8d97f 653 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 26 644 1.8E-294 T 23-04-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: REACT_13433 DC74_RS22085 20fa326589e3b4b3591138bb57b8d97f 653 PANTHER PTHR24095 31 646 1.2E-270 T 23-04-2016 DC74_RS22085 20fa326589e3b4b3591138bb57b8d97f 653 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 11 646 51.177 T 23-04-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: REACT_13433 DC74_RS36630 e31cf33b600b01e01ca7a1ff09474026 193 Pfam PF02342 TerD domain 1 179 9.8E-47 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS36630 e31cf33b600b01e01ca7a1ff09474026 193 PANTHER PTHR32097:SF7 1 190 2.3E-76 T 23-04-2016 DC74_RS36630 e31cf33b600b01e01ca7a1ff09474026 193 Gene3D G3DSA:2.60.60.30 21 182 8.8E-48 T 23-04-2016 DC74_RS36630 e31cf33b600b01e01ca7a1ff09474026 193 PANTHER PTHR32097 1 190 2.3E-76 T 23-04-2016 DC74_RS38335 30ddd60e6bb81e52d7133b6bd784cbaa 245 Gene3D G3DSA:3.40.50.880 15 241 1.1E-35 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS38335 30ddd60e6bb81e52d7133b6bd784cbaa 245 SUPERFAMILY SSF52317 15 242 7.4E-40 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS38335 30ddd60e6bb81e52d7133b6bd784cbaa 245 PANTHER PTHR11550 41 219 8.4E-37 T 23-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 DC74_RS38335 30ddd60e6bb81e52d7133b6bd784cbaa 245 Pfam PF00117 Glutamine amidotransferase class-I 44 234 3.4E-15 T 23-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 DC74_RS14810 d01b977cb350700bc18dd2fc8abf00c6 378 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 9 328 1.4E-110 T 23-04-2016 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 DC74_RS14810 d01b977cb350700bc18dd2fc8abf00c6 378 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 103 121 - T 23-04-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 DC74_RS14810 d01b977cb350700bc18dd2fc8abf00c6 378 SUPERFAMILY SSF51395 16 324 2.2E-79 T 23-04-2016 DC74_RS14810 d01b977cb350700bc18dd2fc8abf00c6 378 Gene3D G3DSA:1.10.1200.80 263 331 3.7E-16 T 23-04-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 DC74_RS14810 d01b977cb350700bc18dd2fc8abf00c6 378 Pfam PF01207 Dihydrouridine synthase (Dus) 19 323 8.1E-94 T 23-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 DC74_RS14810 d01b977cb350700bc18dd2fc8abf00c6 378 PANTHER PTHR11082:SF25 4 374 1.8E-174 T 23-04-2016 DC74_RS14810 d01b977cb350700bc18dd2fc8abf00c6 378 PANTHER PTHR11082 4 374 1.8E-174 T 23-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 DC74_RS14810 d01b977cb350700bc18dd2fc8abf00c6 378 Gene3D G3DSA:3.20.20.70 13 254 6.2E-84 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS14810 d01b977cb350700bc18dd2fc8abf00c6 378 PIRSF PIRSF006621 6 338 5.8E-100 T 23-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 DC74_RS27505 b3978a981c861c4b3d97c7e2ab3a39e4 380 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 274 335 3.2E-19 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS27505 b3978a981c861c4b3d97c7e2ab3a39e4 380 PANTHER PTHR24220:SF535 41 369 1.5E-154 T 23-04-2016 DC74_RS27505 b3978a981c861c4b3d97c7e2ab3a39e4 380 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 273 363 3.8E-23 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DC74_RS27505 b3978a981c861c4b3d97c7e2ab3a39e4 380 SUPERFAMILY SSF52540 40 293 4.73E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27505 b3978a981c861c4b3d97c7e2ab3a39e4 380 Pfam PF00005 ABC transporter 60 222 8.2E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS27505 b3978a981c861c4b3d97c7e2ab3a39e4 380 ProSitePatterns PS00211 ABC transporters family signature. 195 209 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS27505 b3978a981c861c4b3d97c7e2ab3a39e4 380 PANTHER PTHR24220 41 369 1.5E-154 T 23-04-2016 DC74_RS27505 b3978a981c861c4b3d97c7e2ab3a39e4 380 SMART SM00382 68 272 1.2E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS27505 b3978a981c861c4b3d97c7e2ab3a39e4 380 Gene3D G3DSA:3.40.50.300 39 295 1.9E-76 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09605 c28a38c4f7f0037ce5fb83ebe5f3c2a3 187 PANTHER PTHR33909 1 103 4.3E-23 T 23-04-2016 DC74_RS09605 c28a38c4f7f0037ce5fb83ebe5f3c2a3 187 Pfam PF02699 Preprotein translocase subunit 1 76 2.3E-17 T 23-04-2016 IPR003849 Preprotein translocase YajC DC74_RS09605 c28a38c4f7f0037ce5fb83ebe5f3c2a3 187 PANTHER PTHR33909:SF1 1 103 4.3E-23 T 23-04-2016 DC74_RS09605 c28a38c4f7f0037ce5fb83ebe5f3c2a3 187 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 2 79 2.1E-17 T 23-04-2016 IPR003849 Preprotein translocase YajC DC74_RS09605 c28a38c4f7f0037ce5fb83ebe5f3c2a3 187 SMART SM01323 1 79 7.7E-21 T 23-04-2016 IPR003849 Preprotein translocase YajC DC74_RS22500 d5ce84f5dc1ddc10ea21b4606247407c 321 SUPERFAMILY SSF53850 46 319 1.41E-40 T 23-04-2016 DC74_RS22500 d5ce84f5dc1ddc10ea21b4606247407c 321 PANTHER PTHR30177 41 319 4.5E-34 T 23-04-2016 DC74_RS22500 d5ce84f5dc1ddc10ea21b4606247407c 321 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 46 314 8.7E-49 T 23-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 DC74_RS22500 d5ce84f5dc1ddc10ea21b4606247407c 321 Gene3D G3DSA:3.40.190.10 269 320 5.4E-43 T 23-04-2016 DC74_RS22500 d5ce84f5dc1ddc10ea21b4606247407c 321 Gene3D G3DSA:3.40.190.10 42 158 5.4E-43 T 23-04-2016 DC74_RS22500 d5ce84f5dc1ddc10ea21b4606247407c 321 PANTHER PTHR30177:SF12 41 319 4.5E-34 T 23-04-2016 DC74_RS22500 d5ce84f5dc1ddc10ea21b4606247407c 321 Gene3D G3DSA:3.40.190.120 159 256 7.0E-24 T 23-04-2016 DC74_RS08425 bccf48c8f3504eb49c341fc0b4bafd15 341 PANTHER PTHR19959:SF155 52 283 1.3E-15 T 23-04-2016 DC74_RS08425 bccf48c8f3504eb49c341fc0b4bafd15 341 Pfam PF13424 Tetratricopeptide repeat 195 254 3.0E-9 T 23-04-2016 DC74_RS08425 bccf48c8f3504eb49c341fc0b4bafd15 341 SUPERFAMILY SSF48452 173 283 2.66E-12 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS08425 bccf48c8f3504eb49c341fc0b4bafd15 341 Gene3D G3DSA:1.25.40.10 168 286 8.2E-12 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS08425 bccf48c8f3504eb49c341fc0b4bafd15 341 Gene3D G3DSA:1.25.40.10 29 160 1.6E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS08425 bccf48c8f3504eb49c341fc0b4bafd15 341 PANTHER PTHR19959 52 283 1.3E-15 T 23-04-2016 DC74_RS05660 dfdbcece51039ae59d360127e72ea9c7 141 Gene3D G3DSA:3.90.190.10 55 140 3.7E-17 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS05660 dfdbcece51039ae59d360127e72ea9c7 141 SUPERFAMILY SSF52799 50 140 8.63E-19 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS05660 dfdbcece51039ae59d360127e72ea9c7 141 Pfam PF00102 Protein-tyrosine phosphatase 48 115 1.2E-5 T 23-04-2016 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 DC74_RS21720 66ff8f7803024dd2b6625b5c8b253a38 387 SUPERFAMILY SSF117892 38 179 5.23E-26 T 23-04-2016 IPR001107 Band 7 domain DC74_RS21720 66ff8f7803024dd2b6625b5c8b253a38 387 PANTHER PTHR13806 1 294 9.3E-34 T 23-04-2016 IPR027705 Flotillin family DC74_RS21720 66ff8f7803024dd2b6625b5c8b253a38 387 SMART SM00244 2 172 0.0041 T 23-04-2016 IPR001107 Band 7 domain DC74_RS21720 66ff8f7803024dd2b6625b5c8b253a38 387 Pfam PF15975 Flotillin 269 337 4.7E-7 T 23-04-2016 IPR031905 Flotillin, C-terminal domain DC74_RS21720 66ff8f7803024dd2b6625b5c8b253a38 387 PANTHER PTHR13806:SF20 1 294 9.3E-34 T 23-04-2016 DC74_RS21720 66ff8f7803024dd2b6625b5c8b253a38 387 Pfam PF01145 SPFH domain / Band 7 family 23 187 1.1E-18 T 23-04-2016 IPR001107 Band 7 domain DC74_RS25905 97f96419a06fb551a17fd97e3e6a7b36 373 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 163 357 1.0E-35 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS25905 97f96419a06fb551a17fd97e3e6a7b36 373 SMART SM00331 137 357 4.1E-34 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS25905 97f96419a06fb551a17fd97e3e6a7b36 373 PANTHER PTHR21021 105 366 3.5E-36 T 23-04-2016 DC74_RS25905 97f96419a06fb551a17fd97e3e6a7b36 373 SUPERFAMILY SSF81606 187 356 1.31E-9 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS18370 7cb4a206e1229d9d705a6682307b0c5d 399 PANTHER PTHR10909 5 398 7.3E-114 T 23-04-2016 DC74_RS18370 7cb4a206e1229d9d705a6682307b0c5d 399 SUPERFAMILY SSF47203 240 393 3.54E-16 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS18370 7cb4a206e1229d9d705a6682307b0c5d 399 Gene3D G3DSA:2.40.110.10 132 229 1.5E-32 T 23-04-2016 DC74_RS18370 7cb4a206e1229d9d705a6682307b0c5d 399 SUPERFAMILY SSF56645 3 250 3.14E-61 T 23-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 DC74_RS18370 7cb4a206e1229d9d705a6682307b0c5d 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 129 2.2E-16 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS18370 7cb4a206e1229d9d705a6682307b0c5d 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 391 8.6E-19 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS18370 7cb4a206e1229d9d705a6682307b0c5d 399 Gene3D G3DSA:1.10.540.10 5 130 3.2E-22 T 23-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 DC74_RS18370 7cb4a206e1229d9d705a6682307b0c5d 399 Gene3D G3DSA:1.20.140.10 230 396 5.1E-22 T 23-04-2016 DC74_RS18370 7cb4a206e1229d9d705a6682307b0c5d 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 226 1.4E-20 T 23-04-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 DC74_RS18370 7cb4a206e1229d9d705a6682307b0c5d 399 PANTHER PTHR10909:SF229 5 398 7.3E-114 T 23-04-2016 DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 ProSitePatterns PS00221 MIP family signature. 64 72 - T 23-04-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 PANTHER PTHR19139 7 118 2.4E-81 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 Pfam PF00230 Major intrinsic protein 6 257 6.3E-44 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 Gene3D G3DSA:1.20.1080.10 6 261 3.1E-79 T 23-04-2016 IPR023271 Aquaporin-like DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 SUPERFAMILY SSF81338 7 261 4.45E-61 T 23-04-2016 IPR023271 Aquaporin-like DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 PRINTS PR00783 Major intrinsic protein family signature 83 102 1.4E-34 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 PRINTS PR00783 Major intrinsic protein family signature 160 178 1.4E-34 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 PRINTS PR00783 Major intrinsic protein family signature 5 24 1.4E-34 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 PRINTS PR00783 Major intrinsic protein family signature 193 215 1.4E-34 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 PRINTS PR00783 Major intrinsic protein family signature 46 70 1.4E-34 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 PRINTS PR00783 Major intrinsic protein family signature 240 260 1.4E-34 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 PANTHER PTHR19139:SF147 7 118 2.4E-81 T 23-04-2016 DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 PANTHER PTHR19139:SF147 137 261 2.4E-81 T 23-04-2016 DC74_RS10390 974780370436ce73b1f92b41f5bbcee7 262 PANTHER PTHR19139 137 261 2.4E-81 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 DC74_RS05630 cfd72740531a5b0a8b0a971e0f1585f9 353 PANTHER PTHR21266 22 178 1.4E-41 T 23-04-2016 DC74_RS05630 cfd72740531a5b0a8b0a971e0f1585f9 353 Gene3D G3DSA:2.102.10.10 22 130 5.5E-27 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS05630 cfd72740531a5b0a8b0a971e0f1585f9 353 SUPERFAMILY SSF50022 21 130 1.57E-28 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS05630 cfd72740531a5b0a8b0a971e0f1585f9 353 SUPERFAMILY SSF55961 119 342 6.78E-15 T 23-04-2016 DC74_RS05630 cfd72740531a5b0a8b0a971e0f1585f9 353 PANTHER PTHR21266:SF31 22 178 1.4E-41 T 23-04-2016 DC74_RS05630 cfd72740531a5b0a8b0a971e0f1585f9 353 Pfam PF00355 Rieske [2Fe-2S] domain 23 104 1.8E-13 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS12425 eb4b31790fc8d1d6364255b050d59127 321 PANTHER PTHR24220:SF364 1 235 8.7E-115 T 23-04-2016 DC74_RS12425 eb4b31790fc8d1d6364255b050d59127 321 Pfam PF00005 ABC transporter 28 170 2.2E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS12425 eb4b31790fc8d1d6364255b050d59127 321 PANTHER PTHR24220:SF364 252 281 8.7E-115 T 23-04-2016 DC74_RS12425 eb4b31790fc8d1d6364255b050d59127 321 SUPERFAMILY SSF52540 22 235 2.51E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12425 eb4b31790fc8d1d6364255b050d59127 321 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS12425 eb4b31790fc8d1d6364255b050d59127 321 SMART SM00382 36 220 7.9E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS12425 eb4b31790fc8d1d6364255b050d59127 321 PANTHER PTHR24220 252 281 8.7E-115 T 23-04-2016 DC74_RS12425 eb4b31790fc8d1d6364255b050d59127 321 Gene3D G3DSA:3.40.50.300 2 236 1.1E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12425 eb4b31790fc8d1d6364255b050d59127 321 PANTHER PTHR24220 1 235 8.7E-115 T 23-04-2016 DC74_RS38555 34198353923bbd9c40889e4382e4359a 288 PANTHER PTHR35010 1 281 1.3E-74 T 23-04-2016 DC74_RS38555 34198353923bbd9c40889e4382e4359a 288 SUPERFAMILY SSF47413 30 80 3.87E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS38555 34198353923bbd9c40889e4382e4359a 288 SMART SM00530 9 81 4.7E-9 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS38555 34198353923bbd9c40889e4382e4359a 288 PANTHER PTHR35010:SF2 1 281 1.3E-74 T 23-04-2016 DC74_RS38555 34198353923bbd9c40889e4382e4359a 288 Pfam PF13560 Helix-turn-helix domain 5 84 1.6E-19 T 23-04-2016 DC74_RS38555 34198353923bbd9c40889e4382e4359a 288 Gene3D G3DSA:1.10.260.40 3 80 2.5E-17 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS22675 84be55aa13b13c19d3da6d3bc86e496d 171 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 26 115 2.7E-5 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS22675 84be55aa13b13c19d3da6d3bc86e496d 171 Gene3D G3DSA:2.30.110.10 24 163 5.1E-15 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS22675 84be55aa13b13c19d3da6d3bc86e496d 171 SUPERFAMILY SSF50475 24 165 1.39E-18 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS23670 c5d2570c11e7964ddec544bfd2d7b7c3 263 Pfam PF00005 ABC transporter 17 164 8.5E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS23670 c5d2570c11e7964ddec544bfd2d7b7c3 263 PANTHER PTHR24220 2 253 5.8E-144 T 23-04-2016 DC74_RS23670 c5d2570c11e7964ddec544bfd2d7b7c3 263 PANTHER PTHR24220:SF438 2 253 5.8E-144 T 23-04-2016 DC74_RS23670 c5d2570c11e7964ddec544bfd2d7b7c3 263 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS23670 c5d2570c11e7964ddec544bfd2d7b7c3 263 SUPERFAMILY SSF52540 5 219 6.55E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23670 c5d2570c11e7964ddec544bfd2d7b7c3 263 Gene3D G3DSA:3.40.50.300 1 233 1.5E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS23670 c5d2570c11e7964ddec544bfd2d7b7c3 263 SMART SM00382 25 222 4.0E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS18365 ae966c7e48ff2af2040d16d700887d0e 357 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 142 2.9E-26 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS18365 ae966c7e48ff2af2040d16d700887d0e 357 SUPERFAMILY SSF51735 147 320 7.8E-42 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18365 ae966c7e48ff2af2040d16d700887d0e 357 Gene3D G3DSA:3.40.50.720 178 290 8.1E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18365 ae966c7e48ff2af2040d16d700887d0e 357 Pfam PF00107 Zinc-binding dehydrogenase 185 311 2.3E-23 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DC74_RS18365 ae966c7e48ff2af2040d16d700887d0e 357 PANTHER PTHR11695:SF571 12 355 5.0E-108 T 23-04-2016 DC74_RS18365 ae966c7e48ff2af2040d16d700887d0e 357 SUPERFAMILY SSF50129 9 181 1.48E-50 T 23-04-2016 IPR011032 GroES-like DC74_RS18365 ae966c7e48ff2af2040d16d700887d0e 357 PANTHER PTHR11695 12 355 5.0E-108 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS18365 ae966c7e48ff2af2040d16d700887d0e 357 Gene3D G3DSA:3.90.180.10 1 177 6.0E-57 T 23-04-2016 IPR011032 GroES-like DC74_RS18365 ae966c7e48ff2af2040d16d700887d0e 357 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS18365 ae966c7e48ff2af2040d16d700887d0e 357 SMART SM00829 8 353 3.9E-6 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS13180 e37cff4fda1c7c9675d09c45786d24f1 273 Pfam PF13444 Acetyltransferase (GNAT) domain 56 154 1.4E-27 T 23-04-2016 DC74_RS13180 e37cff4fda1c7c9675d09c45786d24f1 273 SUPERFAMILY SSF55729 39 245 1.42E-37 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS13180 e37cff4fda1c7c9675d09c45786d24f1 273 PANTHER PTHR37323 33 271 1.4E-69 T 23-04-2016 DC74_RS13180 e37cff4fda1c7c9675d09c45786d24f1 273 PANTHER PTHR37323:SF1 33 271 1.4E-69 T 23-04-2016 DC74_RS13180 e37cff4fda1c7c9675d09c45786d24f1 273 Gene3D G3DSA:3.40.630.30 44 177 1.3E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS00945 526cd40b09182bea189a77e136b2519e 216 PANTHER PTHR30055 4 200 3.1E-29 T 23-04-2016 DC74_RS00945 526cd40b09182bea189a77e136b2519e 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 2.9E-16 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00945 526cd40b09182bea189a77e136b2519e 216 SUPERFAMILY SSF46689 8 92 5.82E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00945 526cd40b09182bea189a77e136b2519e 216 SUPERFAMILY SSF48498 88 202 3.11E-14 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS00945 526cd40b09182bea189a77e136b2519e 216 Pfam PF13977 Bacterial transcriptional repressor 89 199 1.2E-6 T 23-04-2016 DC74_RS00945 526cd40b09182bea189a77e136b2519e 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 6.1E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00945 526cd40b09182bea189a77e136b2519e 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 6.1E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS00945 526cd40b09182bea189a77e136b2519e 216 Gene3D G3DSA:1.10.357.10 9 202 5.7E-34 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS39035 1834168589cb33042f4b60e8e6cf7d5d 380 Gene3D G3DSA:3.20.20.10 19 221 5.1E-13 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS39035 1834168589cb33042f4b60e8e6cf7d5d 380 SMART SM01119 271 366 2.6E-20 T 23-04-2016 IPR026956 D-serine dehydratase-like domain DC74_RS39035 1834168589cb33042f4b60e8e6cf7d5d 380 SUPERFAMILY SSF51419 16 228 1.23E-27 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS39035 1834168589cb33042f4b60e8e6cf7d5d 380 PANTHER PTHR28004 6 375 2.5E-59 T 23-04-2016 DC74_RS39035 1834168589cb33042f4b60e8e6cf7d5d 380 Pfam PF01168 Alanine racemase, N-terminal domain 16 221 7.4E-17 T 23-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS39035 1834168589cb33042f4b60e8e6cf7d5d 380 PANTHER PTHR28004:SF1 6 375 2.5E-59 T 23-04-2016 DC74_RS39035 1834168589cb33042f4b60e8e6cf7d5d 380 Pfam PF14031 Putative serine dehydratase domain 271 365 4.7E-13 T 23-04-2016 IPR026956 D-serine dehydratase-like domain DC74_RS01590 848b4adc7517bf52fc35d3b570ab7f39 176 Gene3D G3DSA:3.40.50.620 6 147 4.1E-23 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS01590 848b4adc7517bf52fc35d3b570ab7f39 176 Pfam PF00582 Universal stress protein family 7 146 1.6E-16 T 23-04-2016 IPR006016 UspA GO:0006950 DC74_RS01590 848b4adc7517bf52fc35d3b570ab7f39 176 SUPERFAMILY SSF52402 7 149 4.78E-23 T 23-04-2016 DC74_RS01590 848b4adc7517bf52fc35d3b570ab7f39 176 PANTHER PTHR31964 7 147 3.5E-18 T 23-04-2016 DC74_RS39180 db8795a0e7610f871c6ca2428e71ea53 387 SUPERFAMILY SSF56801 55 350 4.58E-7 T 23-04-2016 DC74_RS39180 db8795a0e7610f871c6ca2428e71ea53 387 Pfam PF04443 Acyl-protein synthetase, LuxE 78 382 1.9E-27 T 23-04-2016 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723|UniPathway: UPA00569 DC74_RS31085 b71372ed8677246d1327dfab1ac5da22 118 SUPERFAMILY SSF46785 21 104 7.28E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31085 b71372ed8677246d1327dfab1ac5da22 118 PANTHER PTHR33154 13 117 5.7E-22 T 23-04-2016 DC74_RS31085 b71372ed8677246d1327dfab1ac5da22 118 Pfam PF12840 Helix-turn-helix domain 27 85 9.9E-11 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31085 b71372ed8677246d1327dfab1ac5da22 118 SMART SM00418 27 105 3.8E-18 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS31085 b71372ed8677246d1327dfab1ac5da22 118 Gene3D G3DSA:1.10.10.10 14 109 4.5E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31085 b71372ed8677246d1327dfab1ac5da22 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 44 2.7E-11 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS31085 b71372ed8677246d1327dfab1ac5da22 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 76 91 2.7E-11 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS31085 b71372ed8677246d1327dfab1ac5da22 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 2.7E-11 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS10695 8ca0a32c7c51c2d45fc9cbe4441a1930 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 68 1.6E-17 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10695 8ca0a32c7c51c2d45fc9cbe4441a1930 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.0E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10695 8ca0a32c7c51c2d45fc9cbe4441a1930 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.0E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS10695 8ca0a32c7c51c2d45fc9cbe4441a1930 206 Gene3D G3DSA:1.10.10.60 23 53 1.0E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS10695 8ca0a32c7c51c2d45fc9cbe4441a1930 206 PANTHER PTHR30055 9 205 2.5E-44 T 23-04-2016 DC74_RS10695 8ca0a32c7c51c2d45fc9cbe4441a1930 206 Gene3D G3DSA:1.10.357.10 71 205 9.6E-35 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS10695 8ca0a32c7c51c2d45fc9cbe4441a1930 206 Gene3D G3DSA:1.10.10.60 54 70 8.4E-6 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS10695 8ca0a32c7c51c2d45fc9cbe4441a1930 206 SUPERFAMILY SSF48498 92 205 1.01E-20 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS10695 8ca0a32c7c51c2d45fc9cbe4441a1930 206 SUPERFAMILY SSF46689 21 97 2.51E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS10695 8ca0a32c7c51c2d45fc9cbe4441a1930 206 PANTHER PTHR30055:SF75 9 205 2.5E-44 T 23-04-2016 DC74_RS12290 ccfac1e8e95a77291109eff8431731cb 270 Gene3D G3DSA:3.40.30.10 90 257 1.4E-30 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS12290 ccfac1e8e95a77291109eff8431731cb 270 SUPERFAMILY SSF52833 80 257 2.43E-27 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS12290 ccfac1e8e95a77291109eff8431731cb 270 Pfam PF13462 Thioredoxin 87 257 4.7E-25 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS12290 ccfac1e8e95a77291109eff8431731cb 270 PANTHER PTHR13887:SF14 16 244 6.1E-30 T 23-04-2016 DC74_RS12290 ccfac1e8e95a77291109eff8431731cb 270 PANTHER PTHR13887 16 244 6.1E-30 T 23-04-2016 DC74_RS40695 b920997d513ab770efda36d43a10194a 636 SUPERFAMILY SSF51735 423 624 9.54E-8 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS40695 b920997d513ab770efda36d43a10194a 636 Gene3D G3DSA:3.40.50.720 495 594 2.7E-4 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS29550 bbabce4843b67185e2fd15dc4ac967b9 114 Gene3D G3DSA:1.10.1200.10 12 89 1.5E-8 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29550 bbabce4843b67185e2fd15dc4ac967b9 114 Pfam PF00550 Phosphopantetheine attachment site 20 83 2.9E-4 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS29550 bbabce4843b67185e2fd15dc4ac967b9 114 SUPERFAMILY SSF47336 16 94 9.16E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS33220 d0bf4788f074897313a2bd5d561b0d1b 465 PANTHER PTHR10742 1 462 4.6E-167 T 23-04-2016 DC74_RS33220 d0bf4788f074897313a2bd5d561b0d1b 465 Pfam PF01593 Flavin containing amine oxidoreductase 7 449 2.5E-39 T 23-04-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 DC74_RS33220 d0bf4788f074897313a2bd5d561b0d1b 465 PANTHER PTHR10742:SF279 1 462 4.6E-167 T 23-04-2016 DC74_RS33220 d0bf4788f074897313a2bd5d561b0d1b 465 SUPERFAMILY SSF51905 1 316 3.37E-48 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33220 d0bf4788f074897313a2bd5d561b0d1b 465 SUPERFAMILY SSF51905 410 451 3.37E-48 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33220 d0bf4788f074897313a2bd5d561b0d1b 465 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 1 450 4.3E-129 T 23-04-2016 IPR017830 Squalene-associated FAD-dependent desaturase DC74_RS33220 d0bf4788f074897313a2bd5d561b0d1b 465 Gene3D G3DSA:3.50.50.60 216 291 5.4E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33220 d0bf4788f074897313a2bd5d561b0d1b 465 Gene3D G3DSA:3.50.50.60 1 56 5.4E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS33220 d0bf4788f074897313a2bd5d561b0d1b 465 Gene3D G3DSA:3.50.50.60 395 453 5.4E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS21070 0ccd04c3107000249157dc0ae267cf3a 377 SUPERFAMILY SSF46955 11 82 1.36E-17 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS21070 0ccd04c3107000249157dc0ae267cf3a 377 PANTHER PTHR30204:SF13 3 86 3.9E-29 T 23-04-2016 DC74_RS21070 0ccd04c3107000249157dc0ae267cf3a 377 SMART SM00422 11 79 8.2E-12 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS21070 0ccd04c3107000249157dc0ae267cf3a 377 PANTHER PTHR30204 3 86 3.9E-29 T 23-04-2016 DC74_RS21070 0ccd04c3107000249157dc0ae267cf3a 377 Pfam PF13411 MerR HTH family regulatory protein 11 78 2.5E-18 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS21070 0ccd04c3107000249157dc0ae267cf3a 377 Gene3D G3DSA:1.10.1660.10 11 83 1.7E-20 T 23-04-2016 DC74_RS07985 2f24c029f6066cc7430316ab2475bcea 222 Gene3D G3DSA:2.30.110.10 4 194 2.4E-77 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS07985 2f24c029f6066cc7430316ab2475bcea 222 PANTHER PTHR34071 1 212 2.8E-75 T 23-04-2016 DC74_RS07985 2f24c029f6066cc7430316ab2475bcea 222 PANTHER PTHR34071:SF2 1 212 2.8E-75 T 23-04-2016 DC74_RS07985 2f24c029f6066cc7430316ab2475bcea 222 SUPERFAMILY SSF50475 10 194 9.23E-61 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS07985 2f24c029f6066cc7430316ab2475bcea 222 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 25 173 2.1E-51 T 23-04-2016 IPR024747 Pyridoxamine 5'-phosphate oxidase-related DC74_RS25635 161d2d0269cf1530d858a6bb0e91cbc4 418 Pfam PF13742 OB-fold nucleic acid binding domain 12 105 1.7E-17 T 23-04-2016 IPR025824 OB-fold nucleic acid binding domain GO:0003676 DC74_RS25635 161d2d0269cf1530d858a6bb0e91cbc4 418 Pfam PF02601 Exonuclease VII, large subunit 332 397 3.5E-8 T 23-04-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 DC74_RS25635 161d2d0269cf1530d858a6bb0e91cbc4 418 Pfam PF02601 Exonuclease VII, large subunit 129 341 1.1E-59 T 23-04-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 DC74_RS25635 161d2d0269cf1530d858a6bb0e91cbc4 418 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 13 401 8.9E-120 T 23-04-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 DC74_RS25635 161d2d0269cf1530d858a6bb0e91cbc4 418 PANTHER PTHR30008:SF0 3 413 8.0E-137 T 23-04-2016 DC74_RS25635 161d2d0269cf1530d858a6bb0e91cbc4 418 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 5 401 25.095 T 23-04-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 DC74_RS25635 161d2d0269cf1530d858a6bb0e91cbc4 418 PANTHER PTHR30008 3 413 8.0E-137 T 23-04-2016 DC74_RS28070 d2c96d7970f648fd6064a3bffa596d6d 236 SMART SM00943 27 209 2.1E-31 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal DC74_RS28070 d2c96d7970f648fd6064a3bffa596d6d 236 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 29 202 1.6E-18 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal DC74_RS27860 9578fd2d085ec945720d45a6c08a8008 253 SUPERFAMILY SSF56529 46 250 6.15E-80 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS27860 9578fd2d085ec945720d45a6c08a8008 253 Pfam PF10370 Domain of unknown function (DUF2437) 2 50 1.6E-16 T 23-04-2016 IPR018833 Domain of unknown function DUF2437 DC74_RS27860 9578fd2d085ec945720d45a6c08a8008 253 PANTHER PTHR11820 41 252 1.9E-106 T 23-04-2016 DC74_RS27860 9578fd2d085ec945720d45a6c08a8008 253 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 55 249 2.8E-69 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS27860 9578fd2d085ec945720d45a6c08a8008 253 Gene3D G3DSA:3.90.850.10 46 251 3.1E-92 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS26595 fc5f2d9407d09c21f7697129695a5d64 220 Gene3D G3DSA:3.40.390.10 83 210 8.4E-35 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 DC74_RS26595 fc5f2d9407d09c21f7697129695a5d64 220 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 82 212 4.3E-69 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS26595 fc5f2d9407d09c21f7697129695a5d64 220 PIRSF PIRSF016573 1 217 7.3E-94 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS26595 fc5f2d9407d09c21f7697129695a5d64 220 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 170 194 1.4E-56 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS26595 fc5f2d9407d09c21f7697129695a5d64 220 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 88 114 1.4E-56 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS26595 fc5f2d9407d09c21f7697129695a5d64 220 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 197 211 1.4E-56 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS26595 fc5f2d9407d09c21f7697129695a5d64 220 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 120 144 1.4E-56 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS26595 fc5f2d9407d09c21f7697129695a5d64 220 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 145 169 1.4E-56 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS26595 fc5f2d9407d09c21f7697129695a5d64 220 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 89 212 2.0E-51 T 23-04-2016 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 DC74_RS26595 fc5f2d9407d09c21f7697129695a5d64 220 SUPERFAMILY SSF55486 82 209 4.97E-27 T 23-04-2016 DC74_RS07235 1a5815781e0d74642d1c495d0067996e 79 Pfam PF13302 Acetyltransferase (GNAT) domain 36 77 5.6E-6 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS07235 1a5815781e0d74642d1c495d0067996e 79 SUPERFAMILY SSF55729 36 77 2.76E-8 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS07235 1a5815781e0d74642d1c495d0067996e 79 Gene3D G3DSA:3.40.630.30 36 77 1.2E-9 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS38305 342ece7d5214e7c96cb2e360b271f4d3 286 PANTHER PTHR24220:SF186 15 257 2.5E-130 T 23-04-2016 IPR026253 Methionine import ATP-binding protein MetN GO:0005524|GO:0015821|GO:0042626 DC74_RS38305 342ece7d5214e7c96cb2e360b271f4d3 286 Gene3D G3DSA:3.40.50.300 13 251 2.9E-90 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38305 342ece7d5214e7c96cb2e360b271f4d3 286 SUPERFAMILY SSF52540 13 249 1.82E-82 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS38305 342ece7d5214e7c96cb2e360b271f4d3 286 SMART SM00382 39 226 2.0E-18 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS38305 342ece7d5214e7c96cb2e360b271f4d3 286 PANTHER PTHR24220 15 257 2.5E-130 T 23-04-2016 DC74_RS38305 342ece7d5214e7c96cb2e360b271f4d3 286 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS38305 342ece7d5214e7c96cb2e360b271f4d3 286 Pfam PF00005 ABC transporter 31 178 9.7E-36 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS15660 32b0ff70baf88822a08fb5b51fd524e9 688 PANTHER PTHR30509:SF8 327 581 1.2E-17 T 23-04-2016 DC74_RS15660 32b0ff70baf88822a08fb5b51fd524e9 688 Pfam PF13515 Fusaric acid resistance protein-like 385 506 1.0E-16 T 23-04-2016 DC74_RS15660 32b0ff70baf88822a08fb5b51fd524e9 688 Pfam PF12805 FUSC-like inner membrane protein yccS 77 190 2.1E-7 T 23-04-2016 IPR032692 Integral membrane protein YccS, N-terminal DC74_RS15660 32b0ff70baf88822a08fb5b51fd524e9 688 PANTHER PTHR30509 327 581 1.2E-17 T 23-04-2016 DC74_RS37525 aaf32424d8b651d240fcba2a90ba5dda 281 Gene3D G3DSA:3.40.50.720 4 194 8.8E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37525 aaf32424d8b651d240fcba2a90ba5dda 281 PANTHER PTHR14194 5 281 2.6E-58 T 23-04-2016 DC74_RS37525 aaf32424d8b651d240fcba2a90ba5dda 281 SUPERFAMILY SSF51735 5 231 1.02E-47 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37525 aaf32424d8b651d240fcba2a90ba5dda 281 PANTHER PTHR14194:SF21 5 281 2.6E-58 T 23-04-2016 DC74_RS37525 aaf32424d8b651d240fcba2a90ba5dda 281 Pfam PF13460 NAD(P)H-binding 8 182 1.4E-27 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27935 bc0b9634d19ee1be1e91c10c7c2ca32f 288 Pfam PF01553 Acyltransferase 30 155 2.7E-22 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS27935 bc0b9634d19ee1be1e91c10c7c2ca32f 288 Gene3D G3DSA:3.40.1130.10 32 219 7.2E-20 T 23-04-2016 DC74_RS27935 bc0b9634d19ee1be1e91c10c7c2ca32f 288 PANTHER PTHR10434 9 268 1.5E-80 T 23-04-2016 DC74_RS27935 bc0b9634d19ee1be1e91c10c7c2ca32f 288 SMART SM00563 41 159 2.0E-33 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS27935 bc0b9634d19ee1be1e91c10c7c2ca32f 288 SUPERFAMILY SSF69593 4 221 8.11E-40 T 23-04-2016 DC74_RS27935 bc0b9634d19ee1be1e91c10c7c2ca32f 288 PANTHER PTHR10434:SF21 9 268 1.5E-80 T 23-04-2016 DC74_RS17715 6301e170984f9ae6f39b0387812fb40f 515 Pfam PF00743 Flavin-binding monooxygenase-like 10 227 3.6E-16 T 23-04-2016 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 DC74_RS17715 6301e170984f9ae6f39b0387812fb40f 515 PANTHER PTHR23023:SF132 6 490 6.0E-233 T 23-04-2016 DC74_RS17715 6301e170984f9ae6f39b0387812fb40f 515 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 9.6E-6 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS17715 6301e170984f9ae6f39b0387812fb40f 515 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 132 140 9.6E-6 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS17715 6301e170984f9ae6f39b0387812fb40f 515 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 171 195 9.6E-6 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS17715 6301e170984f9ae6f39b0387812fb40f 515 Gene3D G3DSA:3.50.50.60 321 487 6.0E-21 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17715 6301e170984f9ae6f39b0387812fb40f 515 Gene3D G3DSA:3.50.50.60 7 217 1.4E-65 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17715 6301e170984f9ae6f39b0387812fb40f 515 PANTHER PTHR23023 6 490 6.0E-233 T 23-04-2016 DC74_RS17715 6301e170984f9ae6f39b0387812fb40f 515 SUPERFAMILY SSF51905 271 465 1.34E-22 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17715 6301e170984f9ae6f39b0387812fb40f 515 SUPERFAMILY SSF51905 8 224 7.23E-59 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03415 5ef0eb476164781c25268de8434bb0eb 278 SUPERFAMILY SSF51735 6 271 2.05E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03415 5ef0eb476164781c25268de8434bb0eb 278 PANTHER PTHR14194:SF59 1 275 8.2E-64 T 23-04-2016 DC74_RS03415 5ef0eb476164781c25268de8434bb0eb 278 PANTHER PTHR14194 1 275 8.2E-64 T 23-04-2016 DC74_RS03415 5ef0eb476164781c25268de8434bb0eb 278 Pfam PF13460 NAD(P)H-binding 11 172 1.9E-12 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS03415 5ef0eb476164781c25268de8434bb0eb 278 Gene3D G3DSA:3.40.50.720 3 206 1.3E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS06555 add088972b0d1fc4fcb80a2b8c9e6644 290 PANTHER PTHR30151 49 290 3.4E-80 T 23-04-2016 DC74_RS06555 add088972b0d1fc4fcb80a2b8c9e6644 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 278 1.9E-23 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS06555 add088972b0d1fc4fcb80a2b8c9e6644 290 SUPERFAMILY SSF161098 85 266 8.76E-31 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS06555 add088972b0d1fc4fcb80a2b8c9e6644 290 PANTHER PTHR30151:SF18 49 290 3.4E-80 T 23-04-2016 DC74_RS06555 add088972b0d1fc4fcb80a2b8c9e6644 290 Gene3D G3DSA:1.10.3720.10 85 278 1.9E-23 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS33865 ed8153463a13c705f599452d543593ac 214 SUPERFAMILY SSF55846 60 205 4.19E-38 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS33865 ed8153463a13c705f599452d543593ac 214 Gene3D G3DSA:3.40.80.10 55 205 9.7E-41 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS33865 ed8153463a13c705f599452d543593ac 214 PANTHER PTHR30417 8 202 8.0E-63 T 23-04-2016 DC74_RS33865 ed8153463a13c705f599452d543593ac 214 SMART SM00644 60 190 4.3E-38 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS33865 ed8153463a13c705f599452d543593ac 214 PANTHER PTHR30417:SF1 8 202 8.0E-63 T 23-04-2016 DC74_RS33865 ed8153463a13c705f599452d543593ac 214 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 69 190 8.2E-21 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS17680 613692f492c8423f16f74ea545e31c3d 253 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 22 214 1.3E-46 T 23-04-2016 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 DC74_RS17680 613692f492c8423f16f74ea545e31c3d 253 Pfam PF02361 Cobalt transport protein 15 218 1.1E-29 T 23-04-2016 IPR003339 ABC/ECF transporter, transmembrane component DC74_RS17680 613692f492c8423f16f74ea545e31c3d 253 PANTHER PTHR34857 1 251 1.6E-77 T 23-04-2016 DC74_RS17680 613692f492c8423f16f74ea545e31c3d 253 PANTHER PTHR34857:SF2 1 251 1.6E-77 T 23-04-2016 DC74_RS17780 29b8ff267f892814850d955f263feb00 131 SUPERFAMILY SSF46785 10 83 5.93E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17780 29b8ff267f892814850d955f263feb00 131 PANTHER PTHR38445 3 127 2.7E-35 T 23-04-2016 DC74_RS17780 29b8ff267f892814850d955f263feb00 131 SMART SM00345 21 80 8.2E-12 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS17780 29b8ff267f892814850d955f263feb00 131 PANTHER PTHR38445:SF2 3 127 2.7E-35 T 23-04-2016 DC74_RS17780 29b8ff267f892814850d955f263feb00 131 Gene3D G3DSA:1.10.10.10 8 81 1.1E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17780 29b8ff267f892814850d955f263feb00 131 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 80 2.7E-13 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS27180 3ded5341c08ec7cf5d760ee12118e8e9 202 PANTHER PTHR38074:SF1 1 194 6.3E-45 T 23-04-2016 DC74_RS27180 3ded5341c08ec7cf5d760ee12118e8e9 202 PANTHER PTHR38074 1 194 6.3E-45 T 23-04-2016 DC74_RS27180 3ded5341c08ec7cf5d760ee12118e8e9 202 SUPERFAMILY SSF51219 2 199 4.97E-45 T 23-04-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain DC74_RS27180 3ded5341c08ec7cf5d760ee12118e8e9 202 Gene3D G3DSA:3.60.160.10 1 200 2.9E-43 T 23-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 DC74_RS27180 3ded5341c08ec7cf5d760ee12118e8e9 202 Pfam PF01987 Mitochondrial biogenesis AIM24 1 192 2.3E-33 T 23-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 DC74_RS22175 9accef5bb2714ea02596f8f809f201fa 509 SUPERFAMILY SSF53335 168 303 7.86E-25 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS22175 9accef5bb2714ea02596f8f809f201fa 509 PANTHER PTHR18895:SF64 174 354 8.9E-38 T 23-04-2016 DC74_RS22175 9accef5bb2714ea02596f8f809f201fa 509 Pfam PF05175 Methyltransferase small domain 169 288 2.6E-14 T 23-04-2016 IPR007848 Methyltransferase small domain GO:0008168 DC74_RS22175 9accef5bb2714ea02596f8f809f201fa 509 Gene3D G3DSA:3.40.50.150 168 312 1.8E-28 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS22175 9accef5bb2714ea02596f8f809f201fa 509 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 238 244 - T 23-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 DC74_RS22175 9accef5bb2714ea02596f8f809f201fa 509 PANTHER PTHR18895 174 354 8.9E-38 T 23-04-2016 DC74_RS09975 74c45225477c94c7e9dfdb1d0e966a99 317 SUPERFAMILY SSF103481 212 314 1.03E-8 T 23-04-2016 DC74_RS09975 74c45225477c94c7e9dfdb1d0e966a99 317 SUPERFAMILY SSF103481 77 169 1.7E-7 T 23-04-2016 DC74_RS09975 74c45225477c94c7e9dfdb1d0e966a99 317 Pfam PF00892 EamA-like transporter family 179 311 1.7E-12 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS09975 74c45225477c94c7e9dfdb1d0e966a99 317 Pfam PF00892 EamA-like transporter family 36 165 1.4E-10 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS09975 74c45225477c94c7e9dfdb1d0e966a99 317 PANTHER PTHR12715 41 316 2.9E-113 T 23-04-2016 DC74_RS09975 74c45225477c94c7e9dfdb1d0e966a99 317 PANTHER PTHR12715:SF9 41 316 2.9E-113 T 23-04-2016 DC74_RS21835 7f073523bb9cf853295a263ccd917d91 746 Gene3D G3DSA:1.10.600.10 377 717 2.6E-99 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS21835 7f073523bb9cf853295a263ccd917d91 746 Gene3D G3DSA:1.10.600.10 1 317 7.7E-105 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS21835 7f073523bb9cf853295a263ccd917d91 746 SUPERFAMILY SSF48576 386 720 1.38E-66 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS21835 7f073523bb9cf853295a263ccd917d91 746 SUPERFAMILY SSF48576 1 312 2.5E-64 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS01105 280f04638bedfa30e45c3c797a724729 174 Pfam PF14568 SMI1-KNR4 cell-wall 27 147 1.3E-6 T 23-04-2016 DC74_RS01105 280f04638bedfa30e45c3c797a724729 174 Gene3D G3DSA:3.40.1580.10 27 152 2.7E-5 T 23-04-2016 IPR018958 SMI1/KNR4-like domain DC74_RS01105 280f04638bedfa30e45c3c797a724729 174 SUPERFAMILY SSF160631 25 153 1.23E-10 T 23-04-2016 DC74_RS17060 84f2e3471ca75e21b4dfca1558434d12 184 Pfam PF03061 Thioesterase superfamily 38 108 1.6E-20 T 23-04-2016 IPR006683 Thioesterase domain DC74_RS17060 84f2e3471ca75e21b4dfca1558434d12 184 SUPERFAMILY SSF54637 21 172 1.28E-44 T 23-04-2016 IPR029069 HotDog domain DC74_RS17060 84f2e3471ca75e21b4dfca1558434d12 184 PANTHER PTHR11049 13 180 8.3E-68 T 23-04-2016 DC74_RS17060 84f2e3471ca75e21b4dfca1558434d12 184 Gene3D G3DSA:3.10.129.10 19 171 5.2E-55 T 23-04-2016 IPR029069 HotDog domain DC74_RS07040 6d83eb59736195d0f81c372aee45f68d 72 SUPERFAMILY SSF54862 3 61 1.03E-8 T 23-04-2016 DC74_RS07040 6d83eb59736195d0f81c372aee45f68d 72 Gene3D G3DSA:3.30.70.20 3 65 2.2E-13 T 23-04-2016 DC74_RS07040 6d83eb59736195d0f81c372aee45f68d 72 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.0E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS07040 6d83eb59736195d0f81c372aee45f68d 72 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.0E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS07040 6d83eb59736195d0f81c372aee45f68d 72 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 2.0E-5 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS07040 6d83eb59736195d0f81c372aee45f68d 72 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 60 4.3E-9 T 23-04-2016 DC74_RS10595 6d0410be35835b84ff025fada635117b 318 Pfam PF00753 Metallo-beta-lactamase superfamily 39 222 6.7E-22 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS10595 6d0410be35835b84ff025fada635117b 318 Gene3D G3DSA:3.60.15.10 19 243 7.7E-52 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS10595 6d0410be35835b84ff025fada635117b 318 SUPERFAMILY SSF56281 21 275 1.27E-56 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS10595 6d0410be35835b84ff025fada635117b 318 PANTHER PTHR11935 33 239 1.3E-44 T 23-04-2016 DC74_RS10595 6d0410be35835b84ff025fada635117b 318 PANTHER PTHR11935:SF95 33 239 1.3E-44 T 23-04-2016 DC74_RS10595 6d0410be35835b84ff025fada635117b 318 SMART SM00849 42 222 5.2E-28 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS37335 965a2d48db8f471324c46a27accc9413 155 Gene3D G3DSA:1.10.357.10 6 128 7.9E-11 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS37335 965a2d48db8f471324c46a27accc9413 155 SUPERFAMILY SSF48498 31 137 1.27E-13 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS28485 092624d5205ef5bcebf04b58b7a93cb3 106 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 93 4.7E-19 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS28485 092624d5205ef5bcebf04b58b7a93cb3 106 Pfam PF06013 Proteins of 100 residues with WXG 6 88 2.5E-16 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS28485 092624d5205ef5bcebf04b58b7a93cb3 106 Gene3D G3DSA:1.10.287.1060 1 98 1.5E-21 T 23-04-2016 DC74_RS28485 092624d5205ef5bcebf04b58b7a93cb3 106 SUPERFAMILY SSF140453 3 97 5.23E-21 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS34500 74eedeb6e3296a8eb6b90e18592ece1c 315 PANTHER PTHR12304 1 312 4.5E-144 T 23-04-2016 IPR023186 Inosine/uridine-preferring nucleoside hydrolase DC74_RS34500 74eedeb6e3296a8eb6b90e18592ece1c 315 Gene3D G3DSA:3.90.245.10 3 310 4.6E-115 T 23-04-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DC74_RS34500 74eedeb6e3296a8eb6b90e18592ece1c 315 SUPERFAMILY SSF53590 3 311 4.19E-106 T 23-04-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DC74_RS34500 74eedeb6e3296a8eb6b90e18592ece1c 315 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 301 1.5E-77 T 23-04-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DC74_RS34500 74eedeb6e3296a8eb6b90e18592ece1c 315 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 8 18 - T 23-04-2016 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 DC74_RS34500 74eedeb6e3296a8eb6b90e18592ece1c 315 PANTHER PTHR12304:SF12 1 312 4.5E-144 T 23-04-2016 DC74_RS05935 1ad677a8db77f69dcfa4b8816eaccdf4 146 Pfam PF04205 FMN-binding domain 69 141 1.8E-7 T 23-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 DC74_RS05935 1ad677a8db77f69dcfa4b8816eaccdf4 146 SMART SM00900 67 144 6.1E-10 T 23-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 DC74_RS28875 200737e4e958be47b7785d4d052ab929 292 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 7 283 30.502 T 23-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28875 200737e4e958be47b7785d4d052ab929 292 Gene3D G3DSA:3.10.310.10 134 271 3.2E-39 T 23-04-2016 DC74_RS28875 200737e4e958be47b7785d4d052ab929 292 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 7 281 1.5E-64 T 23-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28875 200737e4e958be47b7785d4d052ab929 292 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 78 92 - T 23-04-2016 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28875 200737e4e958be47b7785d4d052ab929 292 Pfam PF01678 Diaminopimelate epimerase 155 276 2.5E-27 T 23-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28875 200737e4e958be47b7785d4d052ab929 292 Pfam PF01678 Diaminopimelate epimerase 9 136 1.4E-33 T 23-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28875 200737e4e958be47b7785d4d052ab929 292 Gene3D G3DSA:3.10.310.10 8 133 1.5E-39 T 23-04-2016 DC74_RS28875 200737e4e958be47b7785d4d052ab929 292 PANTHER PTHR31689 3 287 2.2E-92 T 23-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 DC74_RS28875 200737e4e958be47b7785d4d052ab929 292 SUPERFAMILY SSF54506 7 137 2.54E-33 T 23-04-2016 DC74_RS28875 200737e4e958be47b7785d4d052ab929 292 SUPERFAMILY SSF54506 145 281 3.93E-34 T 23-04-2016 DC74_RS00200 49b383f7af8c6077698048c1c7b8bebf 1514 Gene3D G3DSA:3.30.565.10 69 157 1.4E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS00200 49b383f7af8c6077698048c1c7b8bebf 1514 SUPERFAMILY SSF55874 69 163 1.33E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS29975 4355507ce8d19064e0559fc0b76a110b 429 SUPERFAMILY SSF103473 22 402 1.7E-29 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS29975 4355507ce8d19064e0559fc0b76a110b 429 PANTHER PTHR23542:SF1 5 402 1.7E-43 T 23-04-2016 DC74_RS29975 4355507ce8d19064e0559fc0b76a110b 429 PANTHER PTHR23542 5 402 1.7E-43 T 23-04-2016 DC74_RS29975 4355507ce8d19064e0559fc0b76a110b 429 Gene3D G3DSA:1.20.1250.20 228 403 2.4E-10 T 23-04-2016 DC74_RS29975 4355507ce8d19064e0559fc0b76a110b 429 Gene3D G3DSA:1.20.1250.20 31 198 6.2E-13 T 23-04-2016 DC74_RS29975 4355507ce8d19064e0559fc0b76a110b 429 Pfam PF07690 Major Facilitator Superfamily 40 214 3.5E-9 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS01335 0fc3d477c6cd33763ad7057079d74e26 122 PANTHER PTHR35908 4 119 1.0E-30 T 23-04-2016 DC74_RS01335 0fc3d477c6cd33763ad7057079d74e26 122 PANTHER PTHR35908:SF2 4 119 1.0E-30 T 23-04-2016 DC74_RS01335 0fc3d477c6cd33763ad7057079d74e26 122 Gene3D G3DSA:3.10.180.10 3 120 7.7E-20 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS01335 0fc3d477c6cd33763ad7057079d74e26 122 SUPERFAMILY SSF54593 4 120 2.15E-17 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS23845 232df696c4e2eaf00b00a9ac04e575a6 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.6E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS23845 232df696c4e2eaf00b00a9ac04e575a6 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.6E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS23845 232df696c4e2eaf00b00a9ac04e575a6 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.6E-9 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS23845 232df696c4e2eaf00b00a9ac04e575a6 283 Gene3D G3DSA:3.40.190.10 173 255 5.3E-5 T 23-04-2016 DC74_RS23845 232df696c4e2eaf00b00a9ac04e575a6 283 Gene3D G3DSA:1.10.10.10 2 81 8.4E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23845 232df696c4e2eaf00b00a9ac04e575a6 283 Gene3D G3DSA:3.40.190.10 91 172 1.1E-12 T 23-04-2016 DC74_RS23845 232df696c4e2eaf00b00a9ac04e575a6 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.4E-22 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS23845 232df696c4e2eaf00b00a9ac04e575a6 283 SUPERFAMILY SSF53850 90 282 6.11E-18 T 23-04-2016 DC74_RS23845 232df696c4e2eaf00b00a9ac04e575a6 283 SUPERFAMILY SSF46785 4 83 9.52E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23845 232df696c4e2eaf00b00a9ac04e575a6 283 PANTHER PTHR30346 1 282 4.4E-50 T 23-04-2016 DC74_RS23845 232df696c4e2eaf00b00a9ac04e575a6 283 Pfam PF03466 LysR substrate binding domain 91 282 5.5E-18 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS37955 d28bba8d10b4995a02ce49b2d2b64b1e 2040 Pfam PF14440 Xanthomonas XOO_2897-like deaminase 1828 1932 2.8E-9 T 23-04-2016 IPR032722 Deaminase, Xanthomonas XOO_2897-like DC74_RS37955 d28bba8d10b4995a02ce49b2d2b64b1e 2040 Pfam PF15644 Papain fold toxin 1, glutamine deamidase 1223 1334 8.6E-28 T 23-04-2016 IPR028908 Tox-PL domain DC74_RS21365 a833b0d3a90e0407b48a76f7ece42427 144 Pfam PF01575 MaoC like domain 16 112 6.4E-7 T 23-04-2016 IPR002539 MaoC-like domain DC74_RS21365 a833b0d3a90e0407b48a76f7ece42427 144 SUPERFAMILY SSF54637 16 137 2.11E-22 T 23-04-2016 IPR029069 HotDog domain DC74_RS21365 a833b0d3a90e0407b48a76f7ece42427 144 Gene3D G3DSA:3.10.129.10 17 137 6.2E-19 T 23-04-2016 IPR029069 HotDog domain DC74_RS21900 b3f992249c4f067943be68ea80f7cf1c 323 PANTHER PTHR34203:SF2 81 232 8.5E-21 T 23-04-2016 DC74_RS21900 b3f992249c4f067943be68ea80f7cf1c 323 Pfam PF05050 Methyltransferase FkbM domain 111 253 3.9E-10 T 23-04-2016 IPR006342 Methyltransferase FkbM KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS21900 b3f992249c4f067943be68ea80f7cf1c 323 SUPERFAMILY SSF53335 62 285 1.47E-42 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS21900 b3f992249c4f067943be68ea80f7cf1c 323 PANTHER PTHR34203 81 232 8.5E-21 T 23-04-2016 DC74_RS21900 b3f992249c4f067943be68ea80f7cf1c 323 Gene3D G3DSA:3.40.50.150 91 241 6.8E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS21900 b3f992249c4f067943be68ea80f7cf1c 323 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 109 234 8.5E-28 T 23-04-2016 IPR006342 Methyltransferase FkbM KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS20655 2fda327df3f79167fe1f64e5cd5b7182 183 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 63 181 4.3E-42 T 23-04-2016 IPR021949 Domain of unknown function DUF3566. transmembrane DC74_RS16655 ccdecbf2732f926e3c0d007dc0de8042 178 Pfam PF14016 Protein of unknown function (DUF4232) 39 152 2.0E-8 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS10070 bd8c2e4e4cb91a698ad67455a8291cd0 176 Gene3D G3DSA:3.90.79.10 2 172 6.0E-34 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS10070 bd8c2e4e4cb91a698ad67455a8291cd0 176 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DC74_RS10070 bd8c2e4e4cb91a698ad67455a8291cd0 176 Pfam PF00293 NUDIX domain 42 149 2.1E-17 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS10070 bd8c2e4e4cb91a698ad67455a8291cd0 176 SUPERFAMILY SSF55811 3 173 6.81E-37 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS10070 bd8c2e4e4cb91a698ad67455a8291cd0 176 PANTHER PTHR11839:SF9 2 172 7.2E-38 T 23-04-2016 DC74_RS10070 bd8c2e4e4cb91a698ad67455a8291cd0 176 PANTHER PTHR11839 2 172 7.2E-38 T 23-04-2016 DC74_RS16880 7a788caac7b01d96cb678dbc26ca88d4 390 SUPERFAMILY SSF100950 27 365 1.17E-91 T 23-04-2016 DC74_RS16880 7a788caac7b01d96cb678dbc26ca88d4 390 PANTHER PTHR10233:SF6 26 381 6.3E-133 T 23-04-2016 DC74_RS16880 7a788caac7b01d96cb678dbc26ca88d4 390 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 16 373 34.552 T 23-04-2016 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 DC74_RS16880 7a788caac7b01d96cb678dbc26ca88d4 390 PANTHER PTHR10233 26 381 6.3E-133 T 23-04-2016 DC74_RS16880 7a788caac7b01d96cb678dbc26ca88d4 390 Gene3D G3DSA:3.40.50.10470 173 367 4.3E-55 T 23-04-2016 DC74_RS16880 7a788caac7b01d96cb678dbc26ca88d4 390 Gene3D G3DSA:1.20.120.420 30 172 1.0E-36 T 23-04-2016 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 DC74_RS16880 7a788caac7b01d96cb678dbc26ca88d4 390 Pfam PF01008 Initiation factor 2 subunit family 63 363 5.5E-55 T 23-04-2016 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 DC74_RS16880 7a788caac7b01d96cb678dbc26ca88d4 390 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 48 363 5.0E-79 T 23-04-2016 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 DC74_RS16880 7a788caac7b01d96cb678dbc26ca88d4 390 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 30 362 2.1E-101 T 23-04-2016 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 DC74_RS16195 b5af91c49767b05302b4ec73c9f24259 252 Pfam PF00702 haloacid dehalogenase-like hydrolase 21 213 1.1E-10 T 23-04-2016 DC74_RS16195 b5af91c49767b05302b4ec73c9f24259 252 SUPERFAMILY SSF56784 17 249 6.79E-37 T 23-04-2016 IPR023214 HAD-like domain DC74_RS16195 b5af91c49767b05302b4ec73c9f24259 252 TIGRFAM TIGR03351 PhnX-like: phosphonatase-like hydrolase 22 249 2.2E-68 T 23-04-2016 IPR022468 Phosphonatase-like hydrolase DC74_RS16195 b5af91c49767b05302b4ec73c9f24259 252 PANTHER PTHR18901 17 249 3.3E-23 T 23-04-2016 DC74_RS16195 b5af91c49767b05302b4ec73c9f24259 252 Gene3D G3DSA:3.40.50.1000 70 249 2.4E-29 T 23-04-2016 IPR023214 HAD-like domain DC74_RS24345 b9dac63a1f87b11e6cf0286b3f528758 374 PANTHER PTHR10907 111 283 3.1E-18 T 23-04-2016 DC74_RS24345 b9dac63a1f87b11e6cf0286b3f528758 374 SUPERFAMILY SSF53474 107 368 6.86E-28 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS24345 b9dac63a1f87b11e6cf0286b3f528758 374 Gene3D G3DSA:3.40.50.1820 102 368 2.0E-40 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS24345 b9dac63a1f87b11e6cf0286b3f528758 374 Pfam PF00756 Putative esterase 133 291 5.0E-13 T 23-04-2016 IPR000801 Putative esterase DC74_RS24345 b9dac63a1f87b11e6cf0286b3f528758 374 PANTHER PTHR10907:SF33 111 283 3.1E-18 T 23-04-2016 DC74_RS34815 451f74b7df62c3309d68c10cdab77af4 556 Gene3D G3DSA:2.30.40.10 17 95 5.2E-11 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS34815 451f74b7df62c3309d68c10cdab77af4 556 Pfam PF07969 Amidohydrolase family 60 551 4.5E-101 T 23-04-2016 IPR013108 Amidohydrolase 3 DC74_RS34815 451f74b7df62c3309d68c10cdab77af4 556 PANTHER PTHR22642 24 553 1.2E-133 T 23-04-2016 DC74_RS34815 451f74b7df62c3309d68c10cdab77af4 556 Gene3D G3DSA:2.30.40.10 470 515 8.4E-5 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS34815 451f74b7df62c3309d68c10cdab77af4 556 SUPERFAMILY SSF51556 198 485 2.01E-38 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS34815 451f74b7df62c3309d68c10cdab77af4 556 SUPERFAMILY SSF51556 71 132 2.01E-38 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS34815 451f74b7df62c3309d68c10cdab77af4 556 PANTHER PTHR22642:SF2 24 553 1.2E-133 T 23-04-2016 DC74_RS34815 451f74b7df62c3309d68c10cdab77af4 556 SUPERFAMILY SSF51338 487 509 3.64E-11 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS34815 451f74b7df62c3309d68c10cdab77af4 556 SUPERFAMILY SSF51338 13 72 3.64E-11 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS34815 451f74b7df62c3309d68c10cdab77af4 556 Gene3D G3DSA:3.20.20.140 200 469 1.8E-33 T 23-04-2016 DC74_RS02240 33e0158d089d329ccf6de6c63ac03dbe 196 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 90 191 3.6E-12 T 23-04-2016 IPR005519 Acid phosphatase, class B-like DC74_RS02240 33e0158d089d329ccf6de6c63ac03dbe 196 PANTHER PTHR31284:SF10 41 196 4.5E-14 T 23-04-2016 DC74_RS02240 33e0158d089d329ccf6de6c63ac03dbe 196 Gene3D G3DSA:3.40.50.1000 71 177 3.6E-5 T 23-04-2016 IPR023214 HAD-like domain DC74_RS02240 33e0158d089d329ccf6de6c63ac03dbe 196 SUPERFAMILY SSF56784 69 181 3.16E-6 T 23-04-2016 IPR023214 HAD-like domain DC74_RS02240 33e0158d089d329ccf6de6c63ac03dbe 196 PANTHER PTHR31284 41 196 4.5E-14 T 23-04-2016 DC74_RS25215 8122b1f7d7fad4f8ad23eb1ab650ac59 386 SUPERFAMILY SSF53383 13 385 6.75E-120 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS25215 8122b1f7d7fad4f8ad23eb1ab650ac59 386 PIRSF PIRSF001434 1 386 3.1E-145 T 23-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 DC74_RS25215 8122b1f7d7fad4f8ad23eb1ab650ac59 386 PANTHER PTHR11808:SF57 7 385 4.6E-265 T 23-04-2016 DC74_RS25215 8122b1f7d7fad4f8ad23eb1ab650ac59 386 Gene3D G3DSA:3.40.640.10 10 254 6.6E-102 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS25215 8122b1f7d7fad4f8ad23eb1ab650ac59 386 Gene3D G3DSA:3.90.1150.10 255 385 1.3E-48 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS25215 8122b1f7d7fad4f8ad23eb1ab650ac59 386 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 385 6.7E-148 T 23-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 DC74_RS25215 8122b1f7d7fad4f8ad23eb1ab650ac59 386 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 198 212 - T 23-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 DC74_RS25215 8122b1f7d7fad4f8ad23eb1ab650ac59 386 PANTHER PTHR11808 7 385 4.6E-265 T 23-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 DC74_RS22495 aa44fa34eb241d1c7bef4234f9701741 245 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 47 209 7.0E-25 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS22495 aa44fa34eb241d1c7bef4234f9701741 245 PANTHER PTHR30177 22 222 4.4E-53 T 23-04-2016 DC74_RS22495 aa44fa34eb241d1c7bef4234f9701741 245 Gene3D G3DSA:1.10.3720.10 18 216 2.7E-29 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS22495 aa44fa34eb241d1c7bef4234f9701741 245 SUPERFAMILY SSF161098 22 205 1.44E-36 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS15730 899c2ecce0a932fca45f6f1564b0adc6 135 Gene3D G3DSA:1.10.101.10 73 134 3.6E-19 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS15730 899c2ecce0a932fca45f6f1564b0adc6 135 Pfam PF01471 Putative peptidoglycan binding domain 76 133 2.0E-14 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS15730 899c2ecce0a932fca45f6f1564b0adc6 135 SUPERFAMILY SSF47090 70 134 1.55E-17 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS27630 359a8fb4a6c29532bf12a10d6453f5fa 144 Gene3D G3DSA:3.30.565.10 42 124 5.5E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27630 359a8fb4a6c29532bf12a10d6453f5fa 144 Pfam PF13581 Histidine kinase-like ATPase domain 20 131 4.8E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS27630 359a8fb4a6c29532bf12a10d6453f5fa 144 SUPERFAMILY SSF55874 42 128 1.77E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS34625 fd4f64a84512459c603456cbbb531697 102 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 3 79 18.416 T 23-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 DC74_RS34625 fd4f64a84512459c603456cbbb531697 102 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 6 50 1.5E-16 T 23-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 DC74_RS34625 fd4f64a84512459c603456cbbb531697 102 Pfam PF02416 mttA/Hcf106 family 8 51 1.1E-16 T 23-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 Gene3D G3DSA:3.40.710.10 52 306 7.6E-98 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 PANTHER PTHR35333:SF2 52 306 1.1E-97 T 23-04-2016 DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 PRINTS PR00118 Beta-lactamase class A signature 83 100 1.3E-63 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 PRINTS PR00118 Beta-lactamase class A signature 238 253 1.3E-63 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 PRINTS PR00118 Beta-lactamase class A signature 185 210 1.3E-63 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 PRINTS PR00118 Beta-lactamase class A signature 123 148 1.3E-63 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 PRINTS PR00118 Beta-lactamase class A signature 221 236 1.3E-63 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 PRINTS PR00118 Beta-lactamase class A signature 52 76 1.3E-63 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 PRINTS PR00118 Beta-lactamase class A signature 159 183 1.3E-63 T 23-04-2016 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 Pfam PF13354 Beta-lactamase enzyme family 73 279 9.5E-40 T 23-04-2016 DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 SUPERFAMILY SSF56601 52 303 1.44E-73 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 ProSitePatterns PS00146 Beta-lactamase class-A active site. 85 100 - T 23-04-2016 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 DC74_RS03165 2c30970deffb7c2005aa941760dfced8 307 PANTHER PTHR35333 52 306 1.1E-97 T 23-04-2016 DC74_RS23315 676a26798bcac2cd9e3417b0b888d9e4 248 PANTHER PTHR32125 9 245 5.5E-64 T 23-04-2016 DC74_RS23315 676a26798bcac2cd9e3417b0b888d9e4 248 Gene3D G3DSA:3.90.550.10 9 243 1.9E-70 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS23315 676a26798bcac2cd9e3417b0b888d9e4 248 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 9 241 29.34 T 23-04-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS23315 676a26798bcac2cd9e3417b0b888d9e4 248 SUPERFAMILY SSF53448 10 238 4.51E-54 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS23315 676a26798bcac2cd9e3417b0b888d9e4 248 PANTHER PTHR32125:SF4 9 245 5.5E-64 T 23-04-2016 DC74_RS23315 676a26798bcac2cd9e3417b0b888d9e4 248 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 110 117 - T 23-04-2016 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS23315 676a26798bcac2cd9e3417b0b888d9e4 248 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 11 239 6.0E-66 T 23-04-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS23315 676a26798bcac2cd9e3417b0b888d9e4 248 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 12 238 1.3E-69 T 23-04-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 DC74_RS06155 25c1669cbb8008d6c1baccd6260a7005 351 Gene3D G3DSA:2.130.10.10 15 346 3.0E-39 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS06155 25c1669cbb8008d6c1baccd6260a7005 351 SUPERFAMILY SSF50974 3 333 1.78E-44 T 23-04-2016 IPR011045 Nitrous oxide reductase, N-terminal DC74_RS16375 8666fde8b6aaead933f9ca5b358876f7 110 SUPERFAMILY SSF54285 1 90 5.52E-26 T 23-04-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp DC74_RS16375 8666fde8b6aaead933f9ca5b358876f7 110 Gene3D G3DSA:3.10.20.30 3 88 2.0E-31 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS16375 8666fde8b6aaead933f9ca5b358876f7 110 PANTHER PTHR38031:SF1 1 90 1.7E-20 T 23-04-2016 DC74_RS16375 8666fde8b6aaead933f9ca5b358876f7 110 Pfam PF02597 ThiS family 5 90 2.4E-18 T 23-04-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 DC74_RS16375 8666fde8b6aaead933f9ca5b358876f7 110 PANTHER PTHR38031 1 90 1.7E-20 T 23-04-2016 DC74_RS19050 84606d0dc03b36fdf1b266a1185b2496 460 PANTHER PTHR11780 27 440 7.9E-216 T 23-04-2016 DC74_RS19050 84606d0dc03b36fdf1b266a1185b2496 460 SMART SM00928 348 393 2.3E-26 T 23-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 DC74_RS19050 84606d0dc03b36fdf1b266a1185b2496 460 Pfam PF10531 SLBB domain 264 310 9.2E-7 T 23-04-2016 IPR019554 Soluble ligand binding domain DC74_RS19050 84606d0dc03b36fdf1b266a1185b2496 460 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 350 433 1.1E-31 T 23-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 DC74_RS19050 84606d0dc03b36fdf1b266a1185b2496 460 SUPERFAMILY SSF142984 262 343 3.92E-21 T 23-04-2016 DC74_RS19050 84606d0dc03b36fdf1b266a1185b2496 460 SUPERFAMILY SSF142019 28 259 3.01E-85 T 23-04-2016 DC74_RS19050 84606d0dc03b36fdf1b266a1185b2496 460 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 187 202 - T 23-04-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 DC74_RS19050 84606d0dc03b36fdf1b266a1185b2496 460 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 361 372 - T 23-04-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 DC74_RS19050 84606d0dc03b36fdf1b266a1185b2496 460 SUPERFAMILY SSF140490 344 443 1.96E-37 T 23-04-2016 DC74_RS19050 84606d0dc03b36fdf1b266a1185b2496 460 PANTHER PTHR11780:SF10 27 440 7.9E-216 T 23-04-2016 DC74_RS19050 84606d0dc03b36fdf1b266a1185b2496 460 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 31 433 1.1E-189 T 23-04-2016 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 DC74_RS19050 84606d0dc03b36fdf1b266a1185b2496 460 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 68 239 1.4E-45 T 23-04-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain DC74_RS23185 906636ccf1fa86a8b0c7b8e1efc48d9e 81 Pfam PF02597 ThiS family 1 81 6.6E-7 T 23-04-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 DC74_RS23185 906636ccf1fa86a8b0c7b8e1efc48d9e 81 SUPERFAMILY SSF54285 1 81 3.18E-11 T 23-04-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp DC74_RS23185 906636ccf1fa86a8b0c7b8e1efc48d9e 81 Gene3D G3DSA:3.10.20.30 1 81 4.4E-10 T 23-04-2016 IPR012675 Beta-grasp domain DC74_RS36790 86b5c5ae43eee037c90bff2d8a813fda 159 PANTHER PTHR35525 1 159 5.9E-25 T 23-04-2016 DC74_RS36790 86b5c5ae43eee037c90bff2d8a813fda 159 Gene3D G3DSA:1.10.3300.10 3 159 3.8E-31 T 23-04-2016 IPR023286 ABATE domain DC74_RS36790 86b5c5ae43eee037c90bff2d8a813fda 159 Pfam PF07336 Putative stress-induced transcription regulator 3 109 9.1E-8 T 23-04-2016 IPR010852 Putative stress-induced transcription regulator DC74_RS36790 86b5c5ae43eee037c90bff2d8a813fda 159 SUPERFAMILY SSF160904 3 157 2.62E-35 T 23-04-2016 DC74_RS36790 86b5c5ae43eee037c90bff2d8a813fda 159 Pfam PF11706 CGNR zinc finger 115 157 1.5E-17 T 23-04-2016 IPR021005 Zinc finger, CGNR DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 170 405 1.1E-82 T 23-04-2016 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 PANTHER PTHR21091:SF16 16 34 3.1E-71 T 23-04-2016 DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 PANTHER PTHR21091:SF16 137 403 3.1E-71 T 23-04-2016 DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 12 136 2.0E-18 T 23-04-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 Gene3D G3DSA:3.40.1010.10 170 284 2.6E-40 T 23-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 PANTHER PTHR21091 16 34 3.1E-71 T 23-04-2016 DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 PANTHER PTHR21091 137 403 3.1E-71 T 23-04-2016 DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 Pfam PF13241 Putative NAD(P)-binding 15 122 4.4E-19 T 23-04-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 249 282 - T 23-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 SUPERFAMILY SSF53790 166 405 1.7E-70 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 Gene3D G3DSA:3.30.950.10 285 406 9.4E-42 T 23-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 Gene3D G3DSA:3.40.50.720 10 116 4.1E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 SUPERFAMILY SSF51735 11 114 4.23E-18 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS09795 301135fd8248fcb2e0d2871a6976f058 412 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 171 382 3.2E-47 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 DC74_RS05905 3acba14bb6f037029e244fc183a77cfd 112 SUPERFAMILY SSF54909 4 96 1.17E-28 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS05905 3acba14bb6f037029e244fc183a77cfd 112 Gene3D G3DSA:3.30.70.900 2 95 4.9E-31 T 23-04-2016 DC74_RS05905 3acba14bb6f037029e244fc183a77cfd 112 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 77 5.2E-21 T 23-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain DC74_RS05905 3acba14bb6f037029e244fc183a77cfd 112 PANTHER PTHR33336 1 95 2.7E-26 T 23-04-2016 DC74_RS05905 3acba14bb6f037029e244fc183a77cfd 112 PANTHER PTHR33336:SF5 1 95 2.7E-26 T 23-04-2016 DC74_RS06545 604a8f4b1647c81d631fbf18b89fa2c8 356 SUPERFAMILY SSF50494 136 337 9.53E-21 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS06545 604a8f4b1647c81d631fbf18b89fa2c8 356 Pfam PF13365 Trypsin-like peptidase domain 148 324 3.8E-17 T 23-04-2016 DC74_RS06545 604a8f4b1647c81d631fbf18b89fa2c8 356 Gene3D G3DSA:2.40.10.10 145 227 3.2E-12 T 23-04-2016 DC74_RS06545 604a8f4b1647c81d631fbf18b89fa2c8 356 ProSitePatterns PS00672 Serine proteases, V8 family, histidine active site. 149 163 - T 23-04-2016 IPR028301 Serine proteases, V8 family, histidine active site DC74_RS06545 604a8f4b1647c81d631fbf18b89fa2c8 356 Gene3D G3DSA:2.40.10.10 241 338 2.4E-8 T 23-04-2016 DC74_RS04310 63d9d863c002ed4014ebe7fcb5520617 118 Gene3D G3DSA:1.10.10.10 9 106 1.6E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04310 63d9d863c002ed4014ebe7fcb5520617 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 72 87 7.4E-9 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS04310 63d9d863c002ed4014ebe7fcb5520617 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 7.4E-9 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS04310 63d9d863c002ed4014ebe7fcb5520617 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 25 40 7.4E-9 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS04310 63d9d863c002ed4014ebe7fcb5520617 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 55 7.4E-9 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS04310 63d9d863c002ed4014ebe7fcb5520617 118 Pfam PF01022 Bacterial regulatory protein, arsR family 31 75 1.5E-9 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS04310 63d9d863c002ed4014ebe7fcb5520617 118 PANTHER PTHR33154 1 113 9.6E-19 T 23-04-2016 DC74_RS04310 63d9d863c002ed4014ebe7fcb5520617 118 SUPERFAMILY SSF46785 14 101 2.56E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04310 63d9d863c002ed4014ebe7fcb5520617 118 SMART SM00418 23 101 2.7E-22 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS15390 07d410ca1b5fd8ea4e30a2f0d3260df0 460 ProSitePatterns PS00218 Amino acid permeases signature. 46 76 - T 23-04-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 DC74_RS15390 07d410ca1b5fd8ea4e30a2f0d3260df0 460 PANTHER PTHR11785:SF386 13 457 7.5E-206 T 23-04-2016 DC74_RS15390 07d410ca1b5fd8ea4e30a2f0d3260df0 460 Pfam PF00324 Amino acid permease 21 446 1.1E-109 T 23-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 DC74_RS15390 07d410ca1b5fd8ea4e30a2f0d3260df0 460 PANTHER PTHR11785 13 457 7.5E-206 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS15390 07d410ca1b5fd8ea4e30a2f0d3260df0 460 PIRSF PIRSF006060 6 456 5.8E-72 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS35960 c6f6826f73ae058928c28f7f84f44794 277 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 84 269 4.7E-40 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS35960 c6f6826f73ae058928c28f7f84f44794 277 SMART SM00331 58 269 2.0E-28 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS35960 c6f6826f73ae058928c28f7f84f44794 277 SUPERFAMILY SSF81606 76 269 1.44E-6 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS35960 c6f6826f73ae058928c28f7f84f44794 277 PANTHER PTHR21021 38 277 2.1E-49 T 23-04-2016 DC74_RS35960 c6f6826f73ae058928c28f7f84f44794 277 PANTHER PTHR21021:SF19 38 277 2.1E-49 T 23-04-2016 DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 PANTHER PTHR23501 1 482 5.7E-159 T 23-04-2016 DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 Pfam PF07690 Major Facilitator Superfamily 7 397 8.7E-49 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 PANTHER PTHR23501:SF73 1 482 5.7E-159 T 23-04-2016 DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 Gene3D G3DSA:1.20.1250.20 5 182 9.6E-31 T 23-04-2016 DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 Gene3D G3DSA:1.20.1250.20 451 477 1.4E-18 T 23-04-2016 DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 Gene3D G3DSA:1.20.1250.20 250 408 1.4E-18 T 23-04-2016 DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 5 29 2.1E-9 T 23-04-2016 DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 125 149 2.1E-9 T 23-04-2016 DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 189 207 2.1E-9 T 23-04-2016 DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 388 407 2.1E-9 T 23-04-2016 DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 95 115 2.1E-9 T 23-04-2016 DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 SUPERFAMILY SSF103473 235 407 2.35E-62 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 SUPERFAMILY SSF103473 2 183 2.35E-62 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS32265 4837c8e68e3410990ed7cc6ca0a00608 505 SUPERFAMILY SSF103473 450 474 2.35E-62 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS16890 0093df19b5f6f2b44c2ab72d6cc3a84f 230 Pfam PF13559 Domain of unknown function (DUF4129) 142 205 9.6E-13 T 23-04-2016 IPR025403 Domain of unknown function DUF4129 DC74_RS07480 49bad5143b3c2697dc5210c965ca0dd1 158 SUPERFAMILY SSF55961 1 147 1.05E-37 T 23-04-2016 DC74_RS07480 49bad5143b3c2697dc5210c965ca0dd1 158 Gene3D G3DSA:3.30.530.20 4 146 1.7E-19 T 23-04-2016 IPR023393 START-like domain DC74_RS07480 49bad5143b3c2697dc5210c965ca0dd1 158 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 120 1.0E-13 T 23-04-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain DC74_RS13410 8d847c1d975e88345525f4144cbccecf 221 PIRSF PIRSF000343 2 220 2.5E-69 T 23-04-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 DC74_RS13410 8d847c1d975e88345525f4144cbccecf 221 PANTHER PTHR10720 9 217 5.5E-70 T 23-04-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 DC74_RS13410 8d847c1d975e88345525f4144cbccecf 221 Pfam PF01126 Heme oxygenase 9 212 2.7E-64 T 23-04-2016 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 DC74_RS13410 8d847c1d975e88345525f4144cbccecf 221 Gene3D G3DSA:1.20.910.10 5 215 5.4E-66 T 23-04-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 DC74_RS13410 8d847c1d975e88345525f4144cbccecf 221 SUPERFAMILY SSF48613 9 215 9.88E-62 T 23-04-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 DC74_RS13410 8d847c1d975e88345525f4144cbccecf 221 PRINTS PR00088 Haem oxygenase signature 166 187 1.9E-31 T 23-04-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 DC74_RS13410 8d847c1d975e88345525f4144cbccecf 221 PRINTS PR00088 Haem oxygenase signature 69 94 1.9E-31 T 23-04-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 DC74_RS13410 8d847c1d975e88345525f4144cbccecf 221 PRINTS PR00088 Haem oxygenase signature 9 34 1.9E-31 T 23-04-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 DC74_RS13410 8d847c1d975e88345525f4144cbccecf 221 PRINTS PR00088 Haem oxygenase signature 44 69 1.9E-31 T 23-04-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 DC74_RS13410 8d847c1d975e88345525f4144cbccecf 221 PRINTS PR00088 Haem oxygenase signature 198 216 1.9E-31 T 23-04-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 DC74_RS13410 8d847c1d975e88345525f4144cbccecf 221 PRINTS PR00088 Haem oxygenase signature 122 143 1.9E-31 T 23-04-2016 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 DC74_RS08760 7bbaadd65bf013a214c573ffc54f9a7d 769 Gene3D G3DSA:3.40.50.1820 592 655 6.1E-4 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08760 7bbaadd65bf013a214c573ffc54f9a7d 769 SUPERFAMILY SSF53474 564 671 2.72E-9 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS09640 06391dee65269a258baa82511be5298c 181 Gene3D G3DSA:1.20.1440.20 16 138 8.6E-4 T 23-04-2016 IPR023353 LemA-like domain DC74_RS10250 61133860618e0c2479b397385fc13b8a 409 Pfam PF13936 Helix-turn-helix domain 77 118 1.8E-13 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain DC74_RS10250 61133860618e0c2479b397385fc13b8a 409 Pfam PF00665 Integrase core domain 256 362 3.3E-10 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 DC74_RS10250 61133860618e0c2479b397385fc13b8a 409 PANTHER PTHR10948 71 399 2.9E-86 T 23-04-2016 DC74_RS10250 61133860618e0c2479b397385fc13b8a 409 SUPERFAMILY SSF53098 256 402 3.03E-23 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS10250 61133860618e0c2479b397385fc13b8a 409 Gene3D G3DSA:3.30.420.10 257 401 3.6E-8 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS10250 61133860618e0c2479b397385fc13b8a 409 ProSitePatterns PS01043 Transposases, IS30 family, signature. 349 365 - T 23-04-2016 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 DC74_RS13810 f5fe3d4d6f5ef1e37679845ba02c44ec 613 Pfam PF13454 FAD-NAD(P)-binding 1 150 4.4E-35 T 23-04-2016 DC74_RS13810 f5fe3d4d6f5ef1e37679845ba02c44ec 613 Gene3D G3DSA:3.50.50.60 538 577 3.0E-6 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS13810 f5fe3d4d6f5ef1e37679845ba02c44ec 613 Gene3D G3DSA:3.50.50.60 18 155 3.0E-6 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS10880 aa5b6371f0ebc2328dd271e712626452 371 PANTHER PTHR30011:SF18 237 371 4.2E-39 T 23-04-2016 DC74_RS10880 aa5b6371f0ebc2328dd271e712626452 371 PANTHER PTHR30011:SF18 141 216 4.2E-39 T 23-04-2016 DC74_RS10880 aa5b6371f0ebc2328dd271e712626452 371 PANTHER PTHR30011:SF18 31 123 4.2E-39 T 23-04-2016 DC74_RS10880 aa5b6371f0ebc2328dd271e712626452 371 Gene3D G3DSA:3.20.20.30 11 360 5.2E-79 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10880 aa5b6371f0ebc2328dd271e712626452 371 SUPERFAMILY SSF51679 15 359 2.19E-62 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10880 aa5b6371f0ebc2328dd271e712626452 371 Pfam PF00296 Luciferase-like monooxygenase 23 295 5.9E-25 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS10880 aa5b6371f0ebc2328dd271e712626452 371 PANTHER PTHR30011 237 371 4.2E-39 T 23-04-2016 DC74_RS10880 aa5b6371f0ebc2328dd271e712626452 371 PANTHER PTHR30011 141 216 4.2E-39 T 23-04-2016 DC74_RS10880 aa5b6371f0ebc2328dd271e712626452 371 PANTHER PTHR30011 31 123 4.2E-39 T 23-04-2016 DC74_RS22800 1efeac0008049e912816571bc329aa8b 341 SUPERFAMILY SSF51735 1 123 3.19E-8 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS22800 1efeac0008049e912816571bc329aa8b 341 Gene3D G3DSA:3.40.50.720 1 101 5.4E-9 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS08095 8d903b8b46020171506b8ec6821041f4 156 PANTHER PTHR15160 1 152 2.0E-34 T 23-04-2016 DC74_RS08095 8d903b8b46020171506b8ec6821041f4 156 SUPERFAMILY SSF103256 3 136 6.8E-46 T 23-04-2016 IPR003729 Bifunctional nuclease domain GO:0004518 DC74_RS08095 8d903b8b46020171506b8ec6821041f4 156 Pfam PF02577 Bifunctional nuclease 6 128 1.5E-44 T 23-04-2016 IPR003729 Bifunctional nuclease domain GO:0004518 DC74_RS10910 0c665d3b328b9f265f7b611ab4330aa4 168 Gene3D G3DSA:3.40.630.30 8 143 4.2E-23 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS10910 0c665d3b328b9f265f7b611ab4330aa4 168 Pfam PF00583 Acetyltransferase (GNAT) family 68 142 8.9E-12 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS10910 0c665d3b328b9f265f7b611ab4330aa4 168 SUPERFAMILY SSF55729 14 147 1.29E-23 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS10910 0c665d3b328b9f265f7b611ab4330aa4 168 PANTHER PTHR13947 55 144 5.2E-18 T 23-04-2016 DC74_RS15715 cb6f5ec045723476e8168a26052d9044 306 Pfam PF01261 Xylose isomerase-like TIM barrel 40 230 1.2E-30 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS15715 cb6f5ec045723476e8168a26052d9044 306 SUPERFAMILY SSF51658 11 289 1.83E-50 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS15715 cb6f5ec045723476e8168a26052d9044 306 PANTHER PTHR12110 16 304 8.7E-92 T 23-04-2016 DC74_RS15715 cb6f5ec045723476e8168a26052d9044 306 PANTHER PTHR12110:SF3 16 304 8.7E-92 T 23-04-2016 DC74_RS15715 cb6f5ec045723476e8168a26052d9044 306 Gene3D G3DSA:3.20.20.150 11 305 7.9E-68 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain DC74_RS32760 6339230ce125322e1560456c1a31e9a9 276 PANTHER PTHR23200:SF43 1 259 1.5E-28 T 23-04-2016 DC74_RS32760 6339230ce125322e1560456c1a31e9a9 276 SUPERFAMILY SSF56281 4 271 2.62E-32 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS32760 6339230ce125322e1560456c1a31e9a9 276 Gene3D G3DSA:3.60.15.10 2 269 1.4E-41 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS32760 6339230ce125322e1560456c1a31e9a9 276 SMART SM00849 48 252 1.6E-13 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS32760 6339230ce125322e1560456c1a31e9a9 276 Pfam PF00753 Metallo-beta-lactamase superfamily 53 247 5.5E-22 T 23-04-2016 IPR001279 Metallo-beta-lactamase DC74_RS32760 6339230ce125322e1560456c1a31e9a9 276 PANTHER PTHR23200 1 259 1.5E-28 T 23-04-2016 DC74_RS31975 a997b0b1da9cbfa0d1c6d051ddfe0d4d 103 Gene3D G3DSA:3.30.1360.20 4 98 2.2E-22 T 23-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 DC74_RS31975 a997b0b1da9cbfa0d1c6d051ddfe0d4d 103 PANTHER PTHR12599 1 100 1.6E-21 T 23-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 DC74_RS31975 a997b0b1da9cbfa0d1c6d051ddfe0d4d 103 SUPERFAMILY SSF55248 7 97 1.28E-22 T 23-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 DC74_RS31975 a997b0b1da9cbfa0d1c6d051ddfe0d4d 103 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 5 97 19.999 T 23-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 DC74_RS31975 a997b0b1da9cbfa0d1c6d051ddfe0d4d 103 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 7 96 5.6E-23 T 23-04-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 DC74_RS36545 128523c985c2f5b2a2217a0b1c34b997 559 Pfam PF02543 Carbamoyltransferase N-terminus 12 332 9.3E-38 T 23-04-2016 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 DC74_RS36545 128523c985c2f5b2a2217a0b1c34b997 559 Pfam PF16861 Carbamoyltransferase C-terminus 383 550 1.2E-48 T 23-04-2016 IPR031730 Carbamoyltransferase, C-terminal DC74_RS36545 128523c985c2f5b2a2217a0b1c34b997 559 SUPERFAMILY SSF53067 107 192 3.63E-14 T 23-04-2016 DC74_RS36545 128523c985c2f5b2a2217a0b1c34b997 559 SUPERFAMILY SSF53067 247 333 3.63E-14 T 23-04-2016 DC74_RS36545 128523c985c2f5b2a2217a0b1c34b997 559 SUPERFAMILY SSF53067 11 77 3.63E-14 T 23-04-2016 DC74_RS36545 128523c985c2f5b2a2217a0b1c34b997 559 PANTHER PTHR34847 63 553 8.1E-74 T 23-04-2016 DC74_RS11920 5d006642edef05051871f7ece342b21d 333 Pfam PF03741 Integral membrane protein TerC family 69 275 1.9E-54 T 23-04-2016 IPR005496 Integral membrane protein TerC GO:0016021 DC74_RS11920 5d006642edef05051871f7ece342b21d 333 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 5 312 1.7E-116 T 23-04-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 DC74_RS11920 5d006642edef05051871f7ece342b21d 333 PANTHER PTHR30238 2 324 1.1E-164 T 23-04-2016 DC74_RS11920 5d006642edef05051871f7ece342b21d 333 PANTHER PTHR30238:SF0 2 324 1.1E-164 T 23-04-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 DC74_RS38965 d234c3f76243900a782fe35caba9181b 180 Pfam PF13302 Acetyltransferase (GNAT) domain 17 151 5.8E-21 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS38965 d234c3f76243900a782fe35caba9181b 180 SUPERFAMILY SSF55729 16 175 4.25E-35 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS38965 d234c3f76243900a782fe35caba9181b 180 Gene3D G3DSA:3.40.630.30 17 179 7.6E-39 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS38965 d234c3f76243900a782fe35caba9181b 180 PANTHER PTHR13256:SF21 5 180 5.5E-39 T 23-04-2016 DC74_RS38965 d234c3f76243900a782fe35caba9181b 180 PANTHER PTHR13256 5 180 5.5E-39 T 23-04-2016 DC74_RS13125 0fde15f2f4c6393a301c01beca64e1c4 135 PIRSF PIRSF021697 2 135 7.0E-47 T 23-04-2016 IPR016795 Uncharacterised conserved protein UCP021697, membrane DC74_RS13125 0fde15f2f4c6393a301c01beca64e1c4 135 Pfam PF06271 RDD family 23 128 2.4E-12 T 23-04-2016 IPR010432 RDD DC74_RS28745 55d51b40a5f16d5ee076554443a85fb0 192 Gene3D G3DSA:2.60.60.30 18 185 5.6E-71 T 23-04-2016 DC74_RS28745 55d51b40a5f16d5ee076554443a85fb0 192 PANTHER PTHR32097 1 191 1.1E-90 T 23-04-2016 DC74_RS28745 55d51b40a5f16d5ee076554443a85fb0 192 Pfam PF02342 TerD domain 1 187 5.9E-83 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS26480 6b833908ae79c1acd65bd4cb2fb4b62f 327 SUPERFAMILY SSF111331 1 327 4.71E-52 T 23-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain DC74_RS26480 6b833908ae79c1acd65bd4cb2fb4b62f 327 PANTHER PTHR12358 1 327 3.2E-129 T 23-04-2016 DC74_RS26480 6b833908ae79c1acd65bd4cb2fb4b62f 327 SMART SM00046 2 133 2.7E-11 T 23-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 DC74_RS26480 6b833908ae79c1acd65bd4cb2fb4b62f 327 Gene3D G3DSA:3.40.50.10330 3 73 1.0E-4 T 23-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 DC74_RS26480 6b833908ae79c1acd65bd4cb2fb4b62f 327 PANTHER PTHR12358:SF34 1 327 3.2E-129 T 23-04-2016 DC74_RS26480 6b833908ae79c1acd65bd4cb2fb4b62f 327 Pfam PF00781 Diacylglycerol kinase catalytic domain 2 119 9.4E-28 T 23-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 DC74_RS10305 da9284bf0b9c328fa5aa51356aaabc3a 369 SUPERFAMILY SSF47413 28 88 5.63E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS10305 da9284bf0b9c328fa5aa51356aaabc3a 369 Gene3D G3DSA:3.40.50.2300 201 335 8.0E-38 T 23-04-2016 DC74_RS10305 da9284bf0b9c328fa5aa51356aaabc3a 369 Gene3D G3DSA:1.10.260.40 29 81 8.5E-21 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS10305 da9284bf0b9c328fa5aa51356aaabc3a 369 PANTHER PTHR30146 28 358 5.2E-134 T 23-04-2016 DC74_RS10305 da9284bf0b9c328fa5aa51356aaabc3a 369 Gene3D G3DSA:3.40.50.2300 82 200 2.1E-24 T 23-04-2016 DC74_RS10305 da9284bf0b9c328fa5aa51356aaabc3a 369 SUPERFAMILY SSF53822 87 339 1.29E-46 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS10305 da9284bf0b9c328fa5aa51356aaabc3a 369 Pfam PF13377 Periplasmic binding protein-like domain 196 353 4.7E-31 T 23-04-2016 DC74_RS10305 da9284bf0b9c328fa5aa51356aaabc3a 369 Pfam PF00356 Bacterial regulatory proteins, lacI family 32 77 7.9E-13 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS10305 da9284bf0b9c328fa5aa51356aaabc3a 369 SMART SM00354 28 100 4.1E-19 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 DC74_RS10305 da9284bf0b9c328fa5aa51356aaabc3a 369 PANTHER PTHR30146:SF47 28 358 5.2E-134 T 23-04-2016 DC74_RS08955 ffcbc895b0dbc103f132756b8e2986d5 293 Gene3D G3DSA:3.40.190.10 55 135 9.4E-17 T 23-04-2016 DC74_RS08955 ffcbc895b0dbc103f132756b8e2986d5 293 Gene3D G3DSA:3.40.190.10 242 283 9.4E-17 T 23-04-2016 DC74_RS08955 ffcbc895b0dbc103f132756b8e2986d5 293 Gene3D G3DSA:3.40.190.10 136 239 6.8E-13 T 23-04-2016 DC74_RS08955 ffcbc895b0dbc103f132756b8e2986d5 293 SMART SM00062 57 286 9.4E-20 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS08955 ffcbc895b0dbc103f132756b8e2986d5 293 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 58 283 5.7E-34 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS08955 ffcbc895b0dbc103f132756b8e2986d5 293 SUPERFAMILY SSF53850 12 284 5.66E-37 T 23-04-2016 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 PANTHER PTHR22912:SF138 192 232 9.2E-84 T 23-04-2016 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 213 1.9E-17 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 16 24 1.9E-17 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 124 1.9E-17 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 54 78 1.9E-17 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 185 207 2.4E-19 T 23-04-2016 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 160 2.4E-19 T 23-04-2016 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 33 2.4E-19 T 23-04-2016 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 58 76 2.4E-19 T 23-04-2016 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 PANTHER PTHR22912:SF138 6 176 9.2E-84 T 23-04-2016 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 SUPERFAMILY SSF51905 7 231 1.85E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 PANTHER PTHR22912 192 232 9.2E-84 T 23-04-2016 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 PANTHER PTHR22912 6 176 9.2E-84 T 23-04-2016 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 Gene3D G3DSA:3.50.50.60 30 152 4.2E-18 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 Gene3D G3DSA:3.50.50.60 6 29 3.3E-17 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 Gene3D G3DSA:3.50.50.60 153 233 3.3E-17 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS37515 a63240157fcdd42d4c2cc4223486b01e 237 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 221 1.1E-18 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS03105 5df3f057b268f533994aabd6fd3dc3c8 202 PANTHER PTHR21471 1 199 6.8E-24 T 23-04-2016 DC74_RS03105 5df3f057b268f533994aabd6fd3dc3c8 202 Pfam PF00583 Acetyltransferase (GNAT) family 118 175 1.5E-6 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS03105 5df3f057b268f533994aabd6fd3dc3c8 202 SUPERFAMILY SSF55729 11 194 2.19E-16 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS03105 5df3f057b268f533994aabd6fd3dc3c8 202 PANTHER PTHR21471:SF63 1 199 6.8E-24 T 23-04-2016 DC74_RS03105 5df3f057b268f533994aabd6fd3dc3c8 202 Gene3D G3DSA:3.40.630.30 11 197 9.5E-37 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 SUPERFAMILY SSF89082 164 248 2.35E-12 T 23-04-2016 IPR012925 TipAS antibiotic-recognition domain DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 SUPERFAMILY SSF46955 4 108 1.06E-25 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 SMART SM00422 3 72 5.0E-21 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 Pfam PF13411 MerR HTH family regulatory protein 5 71 6.7E-18 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 Gene3D G3DSA:1.10.1660.10 5 113 4.4E-27 T 23-04-2016 DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 Gene3D G3DSA:1.10.490.50 164 250 1.1E-16 T 23-04-2016 IPR012925 TipAS antibiotic-recognition domain DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 PANTHER PTHR30204:SF27 1 247 4.2E-27 T 23-04-2016 DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 5.9E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 5.9E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 5.9E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 PANTHER PTHR30204 1 247 4.2E-27 T 23-04-2016 DC74_RS00495 84925892bb7926d74a9f149b9e7d6ab2 252 Pfam PF07739 TipAS antibiotic-recognition domain 144 246 4.7E-14 T 23-04-2016 IPR012925 TipAS antibiotic-recognition domain DC74_RS35250 c6a6f4cbcf1488e9c1fc3cab4d6709dc 567 Pfam PF05960 Bacterial protein of unknown function (DUF885) 32 561 9.6E-145 T 23-04-2016 IPR010281 Protein of unknown function DUF885 DC74_RS35250 c6a6f4cbcf1488e9c1fc3cab4d6709dc 567 PANTHER PTHR33361 19 566 2.9E-131 T 23-04-2016 DC74_RS35250 c6a6f4cbcf1488e9c1fc3cab4d6709dc 567 PANTHER PTHR33361:SF6 19 566 2.9E-131 T 23-04-2016 DC74_RS11010 d10db0492c9f019eb65000f8113a003f 361 Pfam PF02153 Prephenate dehydrogenase 17 251 1.9E-55 T 23-04-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 DC74_RS11010 d10db0492c9f019eb65000f8113a003f 361 PANTHER PTHR21363:SF0 1 325 7.2E-57 T 23-04-2016 DC74_RS11010 d10db0492c9f019eb65000f8113a003f 361 SUPERFAMILY SSF55021 295 354 1.92E-5 T 23-04-2016 DC74_RS11010 d10db0492c9f019eb65000f8113a003f 361 SUPERFAMILY SSF51735 5 158 1.18E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11010 d10db0492c9f019eb65000f8113a003f 361 Gene3D G3DSA:3.40.50.720 4 171 3.4E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11010 d10db0492c9f019eb65000f8113a003f 361 PANTHER PTHR21363 1 325 7.2E-57 T 23-04-2016 DC74_RS11010 d10db0492c9f019eb65000f8113a003f 361 SUPERFAMILY SSF48179 165 251 1.36E-20 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 DC74_RS28735 72b78744d8ac8f95f67ef1d3419a1825 386 PANTHER PTHR32097 1 251 1.6E-87 T 23-04-2016 DC74_RS28735 72b78744d8ac8f95f67ef1d3419a1825 386 Gene3D G3DSA:2.60.60.30 18 182 1.7E-60 T 23-04-2016 DC74_RS28735 72b78744d8ac8f95f67ef1d3419a1825 386 Pfam PF02342 TerD domain 1 184 5.0E-75 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS35210 21533a007ddd62ce49bda41e88cba081 100 SUPERFAMILY SSF143212 3 78 1.7E-21 T 23-04-2016 DC74_RS35210 21533a007ddd62ce49bda41e88cba081 100 Pfam PF08962 Domain of unknown function (DUF1876) 6 80 8.2E-27 T 23-04-2016 IPR015057 Protein of unknown function DUF1876 DC74_RS35210 21533a007ddd62ce49bda41e88cba081 100 ProDom PD280340 RV1738/MT1780 MB2665C MB1767 SCO3163 RV2632C/MT2708 4 83 4.0E-11 T 23-04-2016 IPR015057 Protein of unknown function DUF1876 DC74_RS38820 b0f3570ee1a9d06fddfdcba57a2b571b 192 PANTHER PTHR12714 80 192 1.3E-29 T 23-04-2016 DC74_RS38820 b0f3570ee1a9d06fddfdcba57a2b571b 192 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 85 169 1.6E-16 T 23-04-2016 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 DC74_RS04460 95f33e2d81c06930de2f08bdbc5c9461 183 SMART SM00857 9 172 1.2E-14 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS04460 95f33e2d81c06930de2f08bdbc5c9461 183 SUPERFAMILY SSF53041 10 171 1.11E-14 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS04460 95f33e2d81c06930de2f08bdbc5c9461 183 Gene3D G3DSA:3.40.50.1390 11 149 1.4E-12 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS04460 95f33e2d81c06930de2f08bdbc5c9461 183 Pfam PF00239 Resolvase, N terminal domain 11 171 2.7E-15 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DC74_RS34060 88e102660c987ced865545b7cb8bb781 497 SUPERFAMILY SSF100950 65 90 3.52E-35 T 23-04-2016 DC74_RS34060 88e102660c987ced865545b7cb8bb781 497 SUPERFAMILY SSF100950 136 300 3.52E-35 T 23-04-2016 DC74_RS34060 88e102660c987ced865545b7cb8bb781 497 PANTHER PTHR32479 24 486 3.5E-209 T 23-04-2016 DC74_RS34060 88e102660c987ced865545b7cb8bb781 497 Pfam PF13183 4Fe-4S dicluster domain 315 384 3.2E-9 T 23-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DC74_RS34060 88e102660c987ced865545b7cb8bb781 497 Gene3D G3DSA:3.40.50.10420 197 300 1.8E-45 T 23-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain DC74_RS34060 88e102660c987ced865545b7cb8bb781 497 Gene3D G3DSA:3.40.50.10420 66 129 1.8E-45 T 23-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain DC74_RS34060 88e102660c987ced865545b7cb8bb781 497 SUPERFAMILY SSF54862 296 398 5.86E-14 T 23-04-2016 DC74_RS34060 88e102660c987ced865545b7cb8bb781 497 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 71 299 2.9E-48 T 23-04-2016 IPR003741 LUD domain DC74_RS34060 88e102660c987ced865545b7cb8bb781 497 PANTHER PTHR32479:SF10 24 486 3.5E-209 T 23-04-2016 DC74_RS34060 88e102660c987ced865545b7cb8bb781 497 Pfam PF11870 Domain of unknown function (DUF3390) 393 484 7.2E-17 T 23-04-2016 IPR024569 4Fe-4S binding protein, C-terminal DC74_RS34060 88e102660c987ced865545b7cb8bb781 497 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 318 329 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DC74_RS34060 88e102660c987ced865545b7cb8bb781 497 Gene3D G3DSA:1.10.1060.10 313 399 8.2E-11 T 23-04-2016 DC74_RS11955 75b29c1dc8c8f578f767b7f62f530734 153 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 48 148 3.5E-10 T 23-04-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 DC74_RS11955 75b29c1dc8c8f578f767b7f62f530734 153 SUPERFAMILY SSF50118 46 151 3.27E-9 T 23-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor DC74_RS28740 08c04ef6a41e5306ca3a36365d76aea5 226 Pfam PF01464 Transglycosylase SLT domain 78 194 3.4E-5 T 23-04-2016 IPR008258 Transglycosylase SLT domain 1 DC74_RS28740 08c04ef6a41e5306ca3a36365d76aea5 226 Gene3D G3DSA:1.10.530.10 70 213 1.1E-12 T 23-04-2016 DC74_RS28740 08c04ef6a41e5306ca3a36365d76aea5 226 SUPERFAMILY SSF53955 69 218 4.31E-10 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS07320 6c7bd9a15909b1453b5216dd28caaa7b 131 SUPERFAMILY SSF50331 66 129 1.58E-16 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal DC74_RS07320 6c7bd9a15909b1453b5216dd28caaa7b 131 Pfam PF12728 Helix-turn-helix domain 4 49 5.0E-10 T 23-04-2016 DC74_RS07320 6c7bd9a15909b1453b5216dd28caaa7b 131 PANTHER PTHR30432 1 130 7.5E-26 T 23-04-2016 DC74_RS07320 6c7bd9a15909b1453b5216dd28caaa7b 131 Gene3D G3DSA:2.40.50.100 66 128 6.3E-22 T 23-04-2016 DC74_RS07320 6c7bd9a15909b1453b5216dd28caaa7b 131 Gene3D G3DSA:1.10.1660.10 4 48 5.7E-7 T 23-04-2016 DC74_RS07320 6c7bd9a15909b1453b5216dd28caaa7b 131 SUPERFAMILY SSF46955 3 53 5.95E-10 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS07320 6c7bd9a15909b1453b5216dd28caaa7b 131 Pfam PF03459 TOBE domain 66 128 1.8E-17 T 23-04-2016 IPR005116 Transport-associated OB, type 1 DC74_RS18550 ed295c88e3eb490569d3a62bb33f7783 123 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 3 122 5.2E-22 T 23-04-2016 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS18550 ed295c88e3eb490569d3a62bb33f7783 123 Gene3D G3DSA:3.90.470.20 2 122 1.5E-41 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS18550 ed295c88e3eb490569d3a62bb33f7783 123 SUPERFAMILY SSF56214 3 122 4.45E-26 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS18550 ed295c88e3eb490569d3a62bb33f7783 123 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 4 121 1.3E-26 T 23-04-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS18550 ed295c88e3eb490569d3a62bb33f7783 123 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 123 22.625 T 23-04-2016 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS18550 ed295c88e3eb490569d3a62bb33f7783 123 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 84 7.0E-13 T 23-04-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS18550 ed295c88e3eb490569d3a62bb33f7783 123 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 105 2.4E-15 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 DC74_RS33565 35179cf0f021a2eac36c7607e433baf4 279 Pfam PF04075 Domain of unknown function (DUF385) 11 133 1.3E-36 T 23-04-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 DC74_RS33565 35179cf0f021a2eac36c7607e433baf4 279 Gene3D G3DSA:1.20.120.520 146 275 1.5E-27 T 23-04-2016 DC74_RS33565 35179cf0f021a2eac36c7607e433baf4 279 SUPERFAMILY SSF50475 26 136 1.13E-8 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS33565 35179cf0f021a2eac36c7607e433baf4 279 PANTHER PTHR39428 1 274 1.4E-74 T 23-04-2016 DC74_RS33565 35179cf0f021a2eac36c7607e433baf4 279 Gene3D G3DSA:2.30.110.10 26 137 1.1E-9 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS33565 35179cf0f021a2eac36c7607e433baf4 279 Pfam PF01814 Hemerythrin HHE cation binding domain 150 274 3.6E-21 T 23-04-2016 IPR012312 Haemerythrin-like DC74_RS33565 35179cf0f021a2eac36c7607e433baf4 279 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 22 133 2.9E-31 T 23-04-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 DC74_RS33565 35179cf0f021a2eac36c7607e433baf4 279 PANTHER PTHR39428:SF1 1 274 1.4E-74 T 23-04-2016 DC74_RS03975 ed8b4578c270f1ce1e6fc99b73cc4333 210 Pfam PF08445 FR47-like protein 144 200 8.4E-7 T 23-04-2016 IPR013653 FR47-like GO:0016747 DC74_RS03975 ed8b4578c270f1ce1e6fc99b73cc4333 210 SUPERFAMILY SSF55729 102 199 9.73E-12 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS03975 ed8b4578c270f1ce1e6fc99b73cc4333 210 Gene3D G3DSA:3.40.630.30 112 200 5.2E-11 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS37075 d5a7c1562891d692a14350c54b160b75 369 Gene3D G3DSA:3.40.47.10 224 366 3.5E-39 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS37075 d5a7c1562891d692a14350c54b160b75 369 PANTHER PTHR11712 124 365 1.9E-51 T 23-04-2016 DC74_RS37075 d5a7c1562891d692a14350c54b160b75 369 SMART SM00825 Beta-ketoacyl synthase 4 369 2.1E-10 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS37075 d5a7c1562891d692a14350c54b160b75 369 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 214 326 2.5E-29 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS37075 d5a7c1562891d692a14350c54b160b75 369 Gene3D G3DSA:3.40.47.10 5 219 2.0E-27 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS37075 d5a7c1562891d692a14350c54b160b75 369 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 121 137 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site DC74_RS37075 d5a7c1562891d692a14350c54b160b75 369 SUPERFAMILY SSF53901 179 366 5.04E-50 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS37075 d5a7c1562891d692a14350c54b160b75 369 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 202 5.6E-20 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS37075 d5a7c1562891d692a14350c54b160b75 369 SUPERFAMILY SSF53901 5 212 1.75E-33 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS39425 7bdb5f79971f63d58fedb0ea851c07ad 965 Gene3D G3DSA:3.30.2010.10 137 212 1.1E-7 T 23-04-2016 DC74_RS39425 7bdb5f79971f63d58fedb0ea851c07ad 965 Pfam PF01435 Peptidase family M48 170 336 3.9E-6 T 23-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DC74_RS30275 210b5db00c7d0f9e5d836d4a64aa707b 89 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 40 2.1E-8 T 23-04-2016 IPR025161 Putative transposase IS4/IS5 family DC74_RS27705 aed5bdfa2fbe1a7b0c2e25b91614e905 239 Gene3D G3DSA:3.90.50.10 13 103 9.6E-6 T 23-04-2016 IPR014747 Bacterial photosynthetic reaction centre, H-chain, C-terminal GO:0019684|GO:0030077|GO:0045156 DC74_RS27705 aed5bdfa2fbe1a7b0c2e25b91614e905 239 SUPERFAMILY SSF50346 10 113 3.92E-19 T 23-04-2016 IPR011033 PRC-barrel-like DC74_RS27705 aed5bdfa2fbe1a7b0c2e25b91614e905 239 Pfam PF05239 PRC-barrel domain 11 75 2.1E-6 T 23-04-2016 IPR027275 PRC-barrel domain DC74_RS18530 d7bf5fc8ecb609aabf8ef0953509e57e 182 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 13 132 1.1E-29 T 23-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 DC74_RS18530 d7bf5fc8ecb609aabf8ef0953509e57e 182 SUPERFAMILY SSF52540 29 118 6.37E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS18530 d7bf5fc8ecb609aabf8ef0953509e57e 182 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 15 134 2.8E-24 T 23-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 DC74_RS18530 d7bf5fc8ecb609aabf8ef0953509e57e 182 PANTHER PTHR33540 1 141 6.9E-39 T 23-04-2016 DC74_RS18530 d7bf5fc8ecb609aabf8ef0953509e57e 182 Gene3D G3DSA:3.40.50.300 8 173 6.8E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10320 ac9e5f330457cf74f7f86606239894c3 72 Pfam PF05639 Pup-like protein 4 72 2.7E-30 T 23-04-2016 IPR008515 Ubiquitin-like, Pup UniPathway: UPA00997 DC74_RS10320 ac9e5f330457cf74f7f86606239894c3 72 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 41 72 2.9E-21 T 23-04-2016 IPR008515 Ubiquitin-like, Pup UniPathway: UPA00997 DC74_RS10320 ac9e5f330457cf74f7f86606239894c3 72 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 72 17.717 T 23-04-2016 IPR008515 Ubiquitin-like, Pup UniPathway: UPA00997 DC74_RS16925 aee1c10dddb3d2dfd06b5f8d06d44e7c 335 Pfam PF01944 Stage II sporulation protein M 109 283 6.2E-35 T 23-04-2016 IPR002798 Stage II sporulation protein M-like DC74_RS16925 aee1c10dddb3d2dfd06b5f8d06d44e7c 335 PANTHER PTHR35337 1 335 2.6E-46 T 23-04-2016 DC74_RS03340 aac6ac61ae7d5c9b49e87ef649f5b537 283 SUPERFAMILY SSF46955 11 114 6.23E-22 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS03340 aac6ac61ae7d5c9b49e87ef649f5b537 283 Gene3D G3DSA:1.10.1660.10 12 114 3.4E-25 T 23-04-2016 DC74_RS03340 aac6ac61ae7d5c9b49e87ef649f5b537 283 PANTHER PTHR30204 3 271 1.1E-17 T 23-04-2016 DC74_RS03340 aac6ac61ae7d5c9b49e87ef649f5b537 283 SMART SM00422 11 80 1.4E-18 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS03340 aac6ac61ae7d5c9b49e87ef649f5b537 283 Pfam PF13411 MerR HTH family regulatory protein 12 78 8.8E-14 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS33235 c84fc15353c3dcb26ef7f77ebe760c8d 218 Pfam PF01048 Phosphorylase superfamily 36 178 1.4E-14 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS33235 c84fc15353c3dcb26ef7f77ebe760c8d 218 Gene3D G3DSA:3.40.50.1580 34 182 7.4E-18 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS33235 c84fc15353c3dcb26ef7f77ebe760c8d 218 SUPERFAMILY SSF53167 37 182 4.71E-21 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DC74_RS23980 9f75c125901a363f7206789738f42963 447 SUPERFAMILY SSF109854 158 322 1.5E-13 T 23-04-2016 DC74_RS23980 9f75c125901a363f7206789738f42963 447 Pfam PF13490 Putative zinc-finger 88 116 4.8E-6 T 23-04-2016 IPR027383 Putative zinc-finger DC74_RS25895 53ed20f3d77073ff7411948c5bfd8f63 421 SUPERFAMILY SSF55874 296 395 3.46E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS25895 53ed20f3d77073ff7411948c5bfd8f63 421 Pfam PF07730 Histidine kinase 200 265 1.1E-17 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS25895 53ed20f3d77073ff7411948c5bfd8f63 421 PANTHER PTHR24421 62 411 4.6E-68 T 23-04-2016 DC74_RS25895 53ed20f3d77073ff7411948c5bfd8f63 421 PANTHER PTHR24421:SF22 62 411 4.6E-68 T 23-04-2016 DC74_RS31830 c7f0cd9970f1bbc8700daa48c8fef616 310 Pfam PF13354 Beta-lactamase enzyme family 128 262 1.5E-11 T 23-04-2016 DC74_RS31830 c7f0cd9970f1bbc8700daa48c8fef616 310 SUPERFAMILY SSF56601 59 285 7.37E-28 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS31830 c7f0cd9970f1bbc8700daa48c8fef616 310 Gene3D G3DSA:3.40.710.10 59 286 4.8E-27 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS37000 6d115154ba7b7b7f3219d598a88a8279 166 Gene3D G3DSA:3.40.630.30 4 144 1.1E-21 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS37000 6d115154ba7b7b7f3219d598a88a8279 166 SUPERFAMILY SSF55729 6 143 1.69E-19 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS37000 6d115154ba7b7b7f3219d598a88a8279 166 Pfam PF13302 Acetyltransferase (GNAT) domain 36 139 1.3E-15 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS37000 6d115154ba7b7b7f3219d598a88a8279 166 PANTHER PTHR13256 59 143 2.5E-12 T 23-04-2016 DC74_RS26890 3c1573935d2956b732093a17bc1c117f 215 Gene3D G3DSA:3.90.870.10 5 205 3.6E-65 T 23-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain DC74_RS26890 3c1573935d2956b732093a17bc1c117f 215 PANTHER PTHR17490 1 210 8.7E-64 T 23-04-2016 DC74_RS26890 3c1573935d2956b732093a17bc1c117f 215 Pfam PF01300 Telomere recombination 23 197 8.2E-48 T 23-04-2016 IPR006070 YrdC-like domain GO:0003725 DC74_RS26890 3c1573935d2956b732093a17bc1c117f 215 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 13 207 2.2E-56 T 23-04-2016 IPR006070 YrdC-like domain GO:0003725 DC74_RS26890 3c1573935d2956b732093a17bc1c117f 215 SUPERFAMILY SSF55821 2 210 1.89E-57 T 23-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 Gene3D G3DSA:3.40.50.300 1 233 1.8E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 PANTHER PTHR24220 305 384 1.7E-170 T 23-04-2016 DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 PANTHER PTHR24220 3 282 1.7E-170 T 23-04-2016 DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 SMART SM00382 314 495 5.0E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 SMART SM00382 28 219 3.7E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 PANTHER PTHR24220:SF459 305 384 1.7E-170 T 23-04-2016 DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 PANTHER PTHR24220:SF459 3 282 1.7E-170 T 23-04-2016 DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 Gene3D G3DSA:3.40.50.300 289 506 5.4E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 Pfam PF00005 ABC transporter 305 446 1.2E-24 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 Pfam PF00005 ABC transporter 20 170 4.2E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 SUPERFAMILY SSF52540 282 506 3.32E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS13685 310a8296021d50907937140df4dbc2e8 540 SUPERFAMILY SSF52540 2 231 3.55E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34345 ab072b354eb86bd80b0b986cc3f8555c 225 Pfam PF03167 Uracil DNA glycosylase superfamily 55 211 1.0E-17 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like DC74_RS34345 ab072b354eb86bd80b0b986cc3f8555c 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 23-04-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 DC74_RS34345 ab072b354eb86bd80b0b986cc3f8555c 225 PANTHER PTHR11264:SF5 1 225 9.4E-159 T 23-04-2016 DC74_RS34345 ab072b354eb86bd80b0b986cc3f8555c 225 PANTHER PTHR11264 1 225 9.4E-159 T 23-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 DC74_RS34345 ab072b354eb86bd80b0b986cc3f8555c 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 223 33.399 T 23-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 DC74_RS34345 ab072b354eb86bd80b0b986cc3f8555c 225 SMART SM00987 53 212 2.3E-28 T 23-04-2016 DC74_RS34345 ab072b354eb86bd80b0b986cc3f8555c 225 SMART SM00986 53 212 2.3E-28 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like DC74_RS34345 ab072b354eb86bd80b0b986cc3f8555c 225 SUPERFAMILY SSF52141 9 224 6.32E-71 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like DC74_RS34345 ab072b354eb86bd80b0b986cc3f8555c 225 Gene3D G3DSA:3.40.470.10 6 224 5.4E-79 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like DC74_RS26240 2aa90187425fcd628e7e3d47d47155ac 181 Gene3D G3DSA:3.90.79.10 47 161 6.0E-17 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS26240 2aa90187425fcd628e7e3d47d47155ac 181 SUPERFAMILY SSF55811 21 164 4.47E-19 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS26240 2aa90187425fcd628e7e3d47d47155ac 181 Pfam PF00293 NUDIX domain 47 158 1.2E-11 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS15325 a81d8ddb0cea734a4bfdff8597163509 204 SUPERFAMILY SSF52096 20 192 3.77E-67 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS15325 a81d8ddb0cea734a4bfdff8597163509 204 PANTHER PTHR10381:SF22 21 190 1.3E-102 T 23-04-2016 DC74_RS15325 a81d8ddb0cea734a4bfdff8597163509 204 Gene3D G3DSA:3.90.226.10 20 191 4.4E-77 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS15325 a81d8ddb0cea734a4bfdff8597163509 204 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 4 193 40.171 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS15325 a81d8ddb0cea734a4bfdff8597163509 204 PANTHER PTHR10381 21 190 1.3E-102 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA DC74_RS15325 a81d8ddb0cea734a4bfdff8597163509 204 Pfam PF00574 Clp protease 20 191 2.0E-77 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA DC74_RS15325 a81d8ddb0cea734a4bfdff8597163509 204 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 23-04-2016 IPR033135 ClpP, histidine active site DC74_RS15325 a81d8ddb0cea734a4bfdff8597163509 204 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 6.0E-49 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS15325 a81d8ddb0cea734a4bfdff8597163509 204 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 6.0E-49 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS15325 a81d8ddb0cea734a4bfdff8597163509 204 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 6.0E-49 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS15325 a81d8ddb0cea734a4bfdff8597163509 204 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 6.0E-49 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS15325 a81d8ddb0cea734a4bfdff8597163509 204 PRINTS PR00127 Clp protease catalytic subunit P signature 20 35 6.0E-49 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 DC74_RS10885 5ba6b1323b27838add48c6058eafa8d8 322 SMART SM00062 71 304 7.9E-27 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS10885 5ba6b1323b27838add48c6058eafa8d8 322 PANTHER PTHR18966:SF191 67 300 1.1E-19 T 23-04-2016 DC74_RS10885 5ba6b1323b27838add48c6058eafa8d8 322 Gene3D G3DSA:3.40.190.10 151 254 4.1E-25 T 23-04-2016 DC74_RS10885 5ba6b1323b27838add48c6058eafa8d8 322 SUPERFAMILY SSF53850 7 23 3.8E-42 T 23-04-2016 DC74_RS10885 5ba6b1323b27838add48c6058eafa8d8 322 SUPERFAMILY SSF53850 61 302 3.8E-42 T 23-04-2016 DC74_RS10885 5ba6b1323b27838add48c6058eafa8d8 322 Gene3D G3DSA:3.40.190.10 68 150 4.2E-23 T 23-04-2016 DC74_RS10885 5ba6b1323b27838add48c6058eafa8d8 322 Gene3D G3DSA:3.40.190.10 264 301 4.2E-23 T 23-04-2016 DC74_RS10885 5ba6b1323b27838add48c6058eafa8d8 322 PANTHER PTHR18966 67 300 1.1E-19 T 23-04-2016 DC74_RS10885 5ba6b1323b27838add48c6058eafa8d8 322 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 73 301 3.7E-41 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF DC74_RS27310 7de254f5fd43d145e49e85bf3927b426 466 Pfam PF00375 Sodium:dicarboxylate symporter family 26 415 6.9E-99 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS27310 7de254f5fd43d145e49e85bf3927b426 466 PRINTS PR00173 Glutamate-aspartate symporter signature 307 333 1.0E-25 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS27310 7de254f5fd43d145e49e85bf3927b426 466 PRINTS PR00173 Glutamate-aspartate symporter signature 91 116 1.0E-25 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS27310 7de254f5fd43d145e49e85bf3927b426 466 PRINTS PR00173 Glutamate-aspartate symporter signature 206 225 1.0E-25 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS27310 7de254f5fd43d145e49e85bf3927b426 466 PRINTS PR00173 Glutamate-aspartate symporter signature 24 44 1.0E-25 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS27310 7de254f5fd43d145e49e85bf3927b426 466 PRINTS PR00173 Glutamate-aspartate symporter signature 342 361 1.0E-25 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS27310 7de254f5fd43d145e49e85bf3927b426 466 SUPERFAMILY SSF118215 26 416 6.8E-101 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS27310 7de254f5fd43d145e49e85bf3927b426 466 Gene3D G3DSA:1.10.3860.10 22 422 2.7E-102 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS27310 7de254f5fd43d145e49e85bf3927b426 466 PANTHER PTHR11958 19 456 2.6E-247 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS27310 7de254f5fd43d145e49e85bf3927b426 466 PANTHER PTHR11958:SF49 19 456 2.6E-247 T 23-04-2016 DC74_RS08590 8e355a9f41a2f993a577cc408e2f2f1b 312 SUPERFAMILY SSF53474 24 309 2.12E-72 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08590 8e355a9f41a2f993a577cc408e2f2f1b 312 Pfam PF00561 alpha/beta hydrolase fold 51 292 1.2E-19 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS08590 8e355a9f41a2f993a577cc408e2f2f1b 312 PRINTS PR00412 Epoxide hydrolase signature 120 133 2.7E-9 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08590 8e355a9f41a2f993a577cc408e2f2f1b 312 PRINTS PR00412 Epoxide hydrolase signature 285 307 2.7E-9 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08590 8e355a9f41a2f993a577cc408e2f2f1b 312 PRINTS PR00412 Epoxide hydrolase signature 57 75 2.7E-9 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08590 8e355a9f41a2f993a577cc408e2f2f1b 312 PANTHER PTHR10992:SF796 11 310 5.7E-65 T 23-04-2016 DC74_RS08590 8e355a9f41a2f993a577cc408e2f2f1b 312 Gene3D G3DSA:3.40.50.1820 24 309 9.0E-66 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08590 8e355a9f41a2f993a577cc408e2f2f1b 312 PANTHER PTHR10992 11 310 5.7E-65 T 23-04-2016 DC74_RS34475 c9a6a502025e13f874898ede5882ef82 467 SUPERFAMILY SSF63737 32 225 2.35E-33 T 23-04-2016 DC74_RS34475 c9a6a502025e13f874898ede5882ef82 467 Pfam PF01433 Peptidase family M1 46 362 6.6E-42 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS34475 c9a6a502025e13f874898ede5882ef82 467 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 318 333 8.9E-14 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS34475 c9a6a502025e13f874898ede5882ef82 467 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 162 177 8.9E-14 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS34475 c9a6a502025e13f874898ede5882ef82 467 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 209 224 8.9E-14 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS34475 c9a6a502025e13f874898ede5882ef82 467 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 337 349 8.9E-14 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DC74_RS34475 c9a6a502025e13f874898ede5882ef82 467 PANTHER PTHR11533:SF163 48 465 2.9E-74 T 23-04-2016 DC74_RS34475 c9a6a502025e13f874898ede5882ef82 467 SUPERFAMILY SSF55486 249 465 3.37E-51 T 23-04-2016 DC74_RS34475 c9a6a502025e13f874898ede5882ef82 467 PANTHER PTHR11533 48 465 2.9E-74 T 23-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 DC74_RS34475 c9a6a502025e13f874898ede5882ef82 467 Gene3D G3DSA:1.10.390.10 332 465 4.3E-21 T 23-04-2016 DC74_RS32590 99403868815a1ebefc5e01bb8a1c5c0c 223 Gene3D G3DSA:3.20.20.70 18 185 4.0E-16 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS32590 99403868815a1ebefc5e01bb8a1c5c0c 223 Pfam PF04055 Radical SAM superfamily 15 122 6.9E-11 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 DC74_RS32590 99403868815a1ebefc5e01bb8a1c5c0c 223 PANTHER PTHR11228 1 129 4.4E-26 T 23-04-2016 DC74_RS32590 99403868815a1ebefc5e01bb8a1c5c0c 223 PANTHER PTHR11228:SF6 1 129 4.4E-26 T 23-04-2016 DC74_RS32590 99403868815a1ebefc5e01bb8a1c5c0c 223 Pfam PF13394 4Fe-4S single cluster domain 14 108 6.3E-12 T 23-04-2016 DC74_RS32590 99403868815a1ebefc5e01bb8a1c5c0c 223 SUPERFAMILY SSF102114 16 186 3.4E-15 T 23-04-2016 DC74_RS32590 99403868815a1ebefc5e01bb8a1c5c0c 223 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 1 220 33.386 T 23-04-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 DC74_RS32590 99403868815a1ebefc5e01bb8a1c5c0c 223 PIRSF PIRSF000370 1 223 9.9E-43 T 23-04-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 DC74_RS17025 1346131e3586fb63a85f3983fc89f5b6 436 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 134 289 2.8E-45 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS17025 1346131e3586fb63a85f3983fc89f5b6 436 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 134 289 4.5E-47 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS17025 1346131e3586fb63a85f3983fc89f5b6 436 PANTHER PTHR33392 49 410 4.7E-112 T 23-04-2016 DC74_RS17025 1346131e3586fb63a85f3983fc89f5b6 436 PANTHER PTHR33392:SF7 49 410 4.7E-112 T 23-04-2016 DC74_RS38190 7c09c9ca437f50e02d9caf2f48dbeb3c 202 Gene3D G3DSA:3.40.80.10 55 201 2.0E-41 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS38190 7c09c9ca437f50e02d9caf2f48dbeb3c 202 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 65 187 3.4E-20 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS38190 7c09c9ca437f50e02d9caf2f48dbeb3c 202 SMART SM00644 56 186 2.8E-39 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS38190 7c09c9ca437f50e02d9caf2f48dbeb3c 202 PANTHER PTHR30417:SF1 41 200 7.8E-60 T 23-04-2016 DC74_RS38190 7c09c9ca437f50e02d9caf2f48dbeb3c 202 PANTHER PTHR30417 41 200 7.8E-60 T 23-04-2016 DC74_RS38190 7c09c9ca437f50e02d9caf2f48dbeb3c 202 SUPERFAMILY SSF55846 55 200 8.77E-41 T 23-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 DC74_RS37985 2cc4ade9d3af824713a4f9b88912f100 337 Gene3D G3DSA:1.10.10.10 10 98 6.5E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37985 2cc4ade9d3af824713a4f9b88912f100 337 Pfam PF00891 O-methyltransferase 103 321 4.6E-34 T 23-04-2016 IPR001077 O-methyltransferase, family 2 GO:0008171 DC74_RS37985 2cc4ade9d3af824713a4f9b88912f100 337 Gene3D G3DSA:3.40.50.150 99 335 2.7E-61 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS37985 2cc4ade9d3af824713a4f9b88912f100 337 PANTHER PTHR11746 12 335 1.0E-71 T 23-04-2016 DC74_RS37985 2cc4ade9d3af824713a4f9b88912f100 337 SUPERFAMILY SSF46785 12 90 2.12E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37985 2cc4ade9d3af824713a4f9b88912f100 337 PANTHER PTHR11746:SF63 12 335 1.0E-71 T 23-04-2016 DC74_RS37985 2cc4ade9d3af824713a4f9b88912f100 337 SUPERFAMILY SSF53335 95 334 3.41E-44 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS37985 2cc4ade9d3af824713a4f9b88912f100 337 PIRSF PIRSF005739 2 336 4.2E-44 T 23-04-2016 IPR016461 O-methyltransferase COMT-type GO:0008168 DC74_RS13610 1b0372be63d8570402bb7c5661982068 297 SMART SM00646 164 292 7.6E-16 T 23-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 DC74_RS13610 1b0372be63d8570402bb7c5661982068 297 Gene3D G3DSA:3.40.630.40 79 295 4.1E-34 T 23-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 DC74_RS13610 1b0372be63d8570402bb7c5661982068 297 PANTHER PTHR30404 114 296 1.6E-31 T 23-04-2016 DC74_RS13610 1b0372be63d8570402bb7c5661982068 297 PANTHER PTHR30404 67 91 1.6E-31 T 23-04-2016 DC74_RS13610 1b0372be63d8570402bb7c5661982068 297 SUPERFAMILY SSF53187 78 295 2.13E-31 T 23-04-2016 DC74_RS13610 1b0372be63d8570402bb7c5661982068 297 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 81 292 1.3E-33 T 23-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 DC74_RS23590 7c9036f6b97f553516a4cee619273e1a 93 Pfam PF13223 Protein of unknown function (DUF4031) 3 77 2.9E-29 T 23-04-2016 IPR025109 Domain of unknown function DUF4031 DC74_RS04160 6769eb44d19a48f4d9a87cfd3f30f992 124 PANTHER PTHR28259 1 123 3.5E-39 T 23-04-2016 DC74_RS04160 6769eb44d19a48f4d9a87cfd3f30f992 124 TIGRFAM TIGR00494 crcB: protein CrcB 5 119 2.8E-26 T 23-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 DC74_RS04160 6769eb44d19a48f4d9a87cfd3f30f992 124 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 19.17 T 23-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 DC74_RS04160 6769eb44d19a48f4d9a87cfd3f30f992 124 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 115 2.7E-23 T 23-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 DC74_RS32130 8c3ffd42728d2cb19d1cdc6202e37f30 320 PANTHER PTHR30011 41 213 9.0E-16 T 23-04-2016 DC74_RS32130 8c3ffd42728d2cb19d1cdc6202e37f30 320 Pfam PF00296 Luciferase-like monooxygenase 28 290 8.3E-30 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS32130 8c3ffd42728d2cb19d1cdc6202e37f30 320 Gene3D G3DSA:3.20.20.30 4 298 1.8E-40 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS32130 8c3ffd42728d2cb19d1cdc6202e37f30 320 SUPERFAMILY SSF51679 12 298 4.21E-38 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS33645 d1b7dc31452f54e7078d8d2015edc8a4 349 Gene3D G3DSA:1.10.10.10 254 318 1.2E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS33645 d1b7dc31452f54e7078d8d2015edc8a4 349 Pfam PF01022 Bacterial regulatory protein, arsR family 267 302 2.0E-4 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS33645 d1b7dc31452f54e7078d8d2015edc8a4 349 SMART SM00418 252 327 9.0E-5 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS33645 d1b7dc31452f54e7078d8d2015edc8a4 349 SUPERFAMILY SSF46785 262 323 3.89E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29615 c9df06976a16d7af12337443941b7a3c 336 Gene3D G3DSA:1.25.40.10 94 293 0.001 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS04835 772a8d06374068fea13d0ac96f96aabb 134 Gene3D G3DSA:3.10.450.50 6 110 1.8E-14 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS04835 772a8d06374068fea13d0ac96f96aabb 134 Pfam PF07366 SnoaL-like polyketide cyclase 11 111 2.6E-13 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS04835 772a8d06374068fea13d0ac96f96aabb 134 SUPERFAMILY SSF54427 5 111 1.56E-24 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS03420 64b61242766f088075e0e96fcf3c5678 330 PANTHER PTHR11019:SF77 165 316 1.4E-45 T 23-04-2016 DC74_RS03420 64b61242766f088075e0e96fcf3c5678 330 Pfam PF12852 Cupin 2 192 3.1E-47 T 23-04-2016 IPR032783 AraC-type transcription regulator, ligand-binding domain DC74_RS03420 64b61242766f088075e0e96fcf3c5678 330 Pfam PF12833 Helix-turn-helix domain 230 309 3.4E-22 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS03420 64b61242766f088075e0e96fcf3c5678 330 SUPERFAMILY SSF46689 260 311 8.07E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03420 64b61242766f088075e0e96fcf3c5678 330 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 292 308 2.9E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS03420 64b61242766f088075e0e96fcf3c5678 330 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 277 292 2.9E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 DC74_RS03420 64b61242766f088075e0e96fcf3c5678 330 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 304 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 DC74_RS03420 64b61242766f088075e0e96fcf3c5678 330 PANTHER PTHR11019 165 316 1.4E-45 T 23-04-2016 DC74_RS03420 64b61242766f088075e0e96fcf3c5678 330 SMART SM00342 224 308 4.3E-30 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 DC74_RS03420 64b61242766f088075e0e96fcf3c5678 330 SUPERFAMILY SSF46689 210 258 7.17E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03420 64b61242766f088075e0e96fcf3c5678 330 Gene3D G3DSA:1.10.10.60 261 310 2.7E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03420 64b61242766f088075e0e96fcf3c5678 330 Gene3D G3DSA:1.10.10.60 207 260 5.7E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS00090 0f5f13ffee000d79ee4bca6600d0bdaa 120 SUPERFAMILY SSF56399 1 112 2.22E-17 T 23-04-2016 DC74_RS00090 0f5f13ffee000d79ee4bca6600d0bdaa 120 Pfam PF06108 Protein of unknown function (DUF952) 7 101 2.1E-18 T 23-04-2016 IPR009297 Protein of unknown function DUF952 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PANTHER PTHR11922:SF7 1 194 7.6E-78 T 23-04-2016 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PRINTS PR00097 Anthranilate synthase component II signature 5 19 1.1E-33 T 23-04-2016 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PRINTS PR00097 Anthranilate synthase component II signature 173 186 1.1E-33 T 23-04-2016 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PRINTS PR00097 Anthranilate synthase component II signature 102 110 1.1E-33 T 23-04-2016 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PRINTS PR00097 Anthranilate synthase component II signature 49 58 1.1E-33 T 23-04-2016 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PRINTS PR00097 Anthranilate synthase component II signature 77 88 1.1E-33 T 23-04-2016 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PRINTS PR00097 Anthranilate synthase component II signature 122 134 1.1E-33 T 23-04-2016 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 7.9E-13 T 23-04-2016 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 7.9E-13 T 23-04-2016 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PRINTS PR00096 Glutamine amidotransferase superfamily signature 173 186 7.9E-13 T 23-04-2016 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 Gene3D G3DSA:3.40.50.880 4 197 7.7E-64 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 SUPERFAMILY SSF52317 4 196 1.07E-54 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 Pfam PF00117 Glutamine amidotransferase class-I 7 196 1.5E-51 T 23-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 5 194 2.9E-61 T 23-04-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PANTHER PTHR11922 1 194 7.6E-78 T 23-04-2016 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 4.4E-9 T 23-04-2016 DC74_RS20585 31e5472925665d1a2678c477c0c26137 218 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 4.4E-9 T 23-04-2016 DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 PANTHER PTHR33238:SF1 2 227 5.2E-83 T 23-04-2016 DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 Gene3D G3DSA:1.10.60.10 75 133 5.6E-30 T 23-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 SUPERFAMILY SSF47979 65 137 4.19E-26 T 23-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 1.1E-18 T 23-04-2016 IPR022687 DTXR-type HTH domain GO:0003677 DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 SMART SM00529 26 125 3.0E-46 T 23-04-2016 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 Gene3D G3DSA:2.30.30.90 134 229 4.7E-31 T 23-04-2016 DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 PANTHER PTHR33238 2 227 5.2E-83 T 23-04-2016 DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 SUPERFAMILY SSF46785 3 61 4.16E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 SMART SM00899 153 229 5.9E-6 T 23-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 Gene3D G3DSA:1.10.10.10 2 73 1.3E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 Pfam PF04023 FeoA domain 157 228 7.8E-8 T 23-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 SUPERFAMILY SSF50037 130 229 2.11E-22 T 23-04-2016 IPR008988 Transcriptional repressor, C-terminal DC74_RS23915 c560c93491b9301ece70df6ffa1f144b 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 1.5E-29 T 23-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 DC74_RS21910 26c0fa26c654bdfbe66b6e9a9b85245c 262 SUPERFAMILY SSF46785 4 76 2.1E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21910 26c0fa26c654bdfbe66b6e9a9b85245c 262 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 2.7E-21 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS21910 26c0fa26c654bdfbe66b6e9a9b85245c 262 Gene3D G3DSA:3.40.1410.10 67 253 4.9E-46 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS21910 26c0fa26c654bdfbe66b6e9a9b85245c 262 PANTHER PTHR11751 1 100 4.4E-19 T 23-04-2016 DC74_RS21910 26c0fa26c654bdfbe66b6e9a9b85245c 262 Pfam PF07702 UTRA domain 118 251 1.2E-19 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS21910 26c0fa26c654bdfbe66b6e9a9b85245c 262 SUPERFAMILY SSF64288 55 256 7.22E-23 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS21910 26c0fa26c654bdfbe66b6e9a9b85245c 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 7.0E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS21910 26c0fa26c654bdfbe66b6e9a9b85245c 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 7.0E-6 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS21910 26c0fa26c654bdfbe66b6e9a9b85245c 262 SMART SM00866 104 252 4.6E-11 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 DC74_RS21910 26c0fa26c654bdfbe66b6e9a9b85245c 262 Gene3D G3DSA:1.10.10.10 4 66 5.4E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21910 26c0fa26c654bdfbe66b6e9a9b85245c 262 SMART SM00345 8 67 6.3E-19 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS04265 1960d48287826a7f64c49cd2058d1ba2 107 Pfam PF02627 Carboxymuconolactone decarboxylase family 15 97 7.9E-20 T 23-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS04265 1960d48287826a7f64c49cd2058d1ba2 107 SUPERFAMILY SSF69118 8 99 1.01E-27 T 23-04-2016 IPR029032 AhpD-like DC74_RS04265 1960d48287826a7f64c49cd2058d1ba2 107 PANTHER PTHR33570:SF1 8 94 2.4E-37 T 23-04-2016 DC74_RS04265 1960d48287826a7f64c49cd2058d1ba2 107 Gene3D G3DSA:1.20.1290.10 8 104 4.5E-24 T 23-04-2016 IPR029032 AhpD-like DC74_RS04265 1960d48287826a7f64c49cd2058d1ba2 107 PANTHER PTHR33570 8 94 2.4E-37 T 23-04-2016 DC74_RS00085 ddf794a760b5290e66f79ba208a00324 128 SUPERFAMILY SSF141072 9 127 2.88E-29 T 23-04-2016 DC74_RS00085 ddf794a760b5290e66f79ba208a00324 128 SMART SM00237 1 97 1.9E-30 T 23-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 DC74_RS00085 ddf794a760b5290e66f79ba208a00324 128 Pfam PF03160 Calx-beta domain 2 96 6.4E-28 T 23-04-2016 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 DC74_RS00085 ddf794a760b5290e66f79ba208a00324 128 PANTHER PTHR11878 3 127 4.4E-41 T 23-04-2016 DC74_RS03570 4b9a8392a834c79cf3c86280f2b139b3 243 PANTHER PTHR10587 45 239 9.2E-46 T 23-04-2016 DC74_RS03570 4b9a8392a834c79cf3c86280f2b139b3 243 Pfam PF01522 Polysaccharide deacetylase 44 164 5.2E-30 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS03570 4b9a8392a834c79cf3c86280f2b139b3 243 Gene3D G3DSA:3.20.20.370 44 238 8.8E-48 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS03570 4b9a8392a834c79cf3c86280f2b139b3 243 SUPERFAMILY SSF88713 39 238 1.11E-52 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS08395 1dbd01fdd9ae509ce876673ef9c2da03 281 Pfam PF00378 Enoyl-CoA hydratase/isomerase 29 279 2.1E-54 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS08395 1dbd01fdd9ae509ce876673ef9c2da03 281 SUPERFAMILY SSF52096 18 279 7.56E-81 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS08395 1dbd01fdd9ae509ce876673ef9c2da03 281 Gene3D G3DSA:3.90.226.10 20 220 4.6E-62 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS08395 1dbd01fdd9ae509ce876673ef9c2da03 281 Gene3D G3DSA:1.10.12.10 223 279 8.6E-17 T 23-04-2016 IPR014748 Crontonase, C-terminal DC74_RS08395 1dbd01fdd9ae509ce876673ef9c2da03 281 PANTHER PTHR11941 8 278 1.5E-89 T 23-04-2016 DC74_RS39295 e9286386c217d2ba9cf192b89c5c70da 83 Gene3D G3DSA:1.10.1200.10 3 76 4.9E-16 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS39295 e9286386c217d2ba9cf192b89c5c70da 83 SUPERFAMILY SSF47336 4 78 1.19E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS39295 e9286386c217d2ba9cf192b89c5c70da 83 Pfam PF00550 Phosphopantetheine attachment site 12 71 1.4E-5 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS03320 fdf67d359039c1fcb6c32d1fd24481c1 185 PANTHER PTHR13256 7 179 5.0E-33 T 23-04-2016 DC74_RS03320 fdf67d359039c1fcb6c32d1fd24481c1 185 Gene3D G3DSA:3.40.630.30 5 177 6.9E-38 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS03320 fdf67d359039c1fcb6c32d1fd24481c1 185 Pfam PF13302 Acetyltransferase (GNAT) domain 9 147 4.8E-21 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS03320 fdf67d359039c1fcb6c32d1fd24481c1 185 SUPERFAMILY SSF55729 4 172 4.33E-37 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS25120 a149c2f84bdc61a308a0822c82a92fce 494 Gene3D G3DSA:3.40.710.10 144 493 4.6E-85 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS25120 a149c2f84bdc61a308a0822c82a92fce 494 PANTHER PTHR30627 1 493 7.6E-166 T 23-04-2016 DC74_RS25120 a149c2f84bdc61a308a0822c82a92fce 494 Gene3D G3DSA:3.90.1310.10 73 143 9.1E-7 T 23-04-2016 DC74_RS25120 a149c2f84bdc61a308a0822c82a92fce 494 SUPERFAMILY SSF56601 140 493 3.24E-78 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS25120 a149c2f84bdc61a308a0822c82a92fce 494 PANTHER PTHR30627:SF3 1 493 7.6E-166 T 23-04-2016 DC74_RS25120 a149c2f84bdc61a308a0822c82a92fce 494 Pfam PF00905 Penicillin binding protein transpeptidase domain 157 489 4.8E-64 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS13200 191d38d4606654253da60492a26a8126 666 Gene3D G3DSA:1.10.10.10 136 172 1.6E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11050 9dc65c3de4628b22cd1655417a337684 338 PANTHER PTHR13696:SF78 76 335 2.0E-114 T 23-04-2016 DC74_RS11050 9dc65c3de4628b22cd1655417a337684 338 Pfam PF13614 AAA domain 84 259 1.9E-61 T 23-04-2016 IPR025669 AAA domain DC74_RS11050 9dc65c3de4628b22cd1655417a337684 338 Gene3D G3DSA:3.40.50.300 84 335 7.5E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11050 9dc65c3de4628b22cd1655417a337684 338 SUPERFAMILY SSF52540 83 335 1.14E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11050 9dc65c3de4628b22cd1655417a337684 338 PANTHER PTHR13696 76 335 2.0E-114 T 23-04-2016 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 Gene3D G3DSA:3.20.20.70 51 336 7.1E-93 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 SUPERFAMILY SSF51445 50 343 7.72E-78 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 PANTHER PTHR11452:SF12 52 434 2.1E-132 T 23-04-2016 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 SUPERFAMILY SSF51011 344 432 1.87E-17 T 23-04-2016 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 PANTHER PTHR11452 52 434 2.1E-132 T 23-04-2016 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 Pfam PF16499 Alpha galactosidase A 55 408 4.1E-87 T 23-04-2016 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 PRINTS PR00740 Glycosyl hydrolase family 27 signature 128 149 3.1E-46 T 23-04-2016 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 PRINTS PR00740 Glycosyl hydrolase family 27 signature 196 214 3.1E-46 T 23-04-2016 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 PRINTS PR00740 Glycosyl hydrolase family 27 signature 298 319 3.1E-46 T 23-04-2016 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 PRINTS PR00740 Glycosyl hydrolase family 27 signature 50 69 3.1E-46 T 23-04-2016 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 PRINTS PR00740 Glycosyl hydrolase family 27 signature 277 296 3.1E-46 T 23-04-2016 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 PRINTS PR00740 Glycosyl hydrolase family 27 signature 162 179 3.1E-46 T 23-04-2016 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 PRINTS PR00740 Glycosyl hydrolase family 27 signature 87 102 3.1E-46 T 23-04-2016 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 DC74_RS08450 0713cc338bdf73434396462eac46d07d 434 Gene3D G3DSA:2.60.40.1180 337 432 6.0E-23 T 23-04-2016 IPR013780 Glycosyl hydrolase, all-beta DC74_RS12670 35df1060f35ebb4f3d90df65adb8a930 391 Gene3D G3DSA:3.50.50.60 1 78 6.3E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12670 35df1060f35ebb4f3d90df65adb8a930 391 Gene3D G3DSA:3.50.50.60 317 375 6.3E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12670 35df1060f35ebb4f3d90df65adb8a930 391 Gene3D G3DSA:3.50.50.60 137 204 6.3E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12670 35df1060f35ebb4f3d90df65adb8a930 391 SUPERFAMILY SSF54373 220 315 1.24E-20 T 23-04-2016 DC74_RS12670 35df1060f35ebb4f3d90df65adb8a930 391 Pfam PF01266 FAD dependent oxidoreductase 1 354 4.9E-63 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DC74_RS12670 35df1060f35ebb4f3d90df65adb8a930 391 SUPERFAMILY SSF51905 1 219 1.81E-47 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12670 35df1060f35ebb4f3d90df65adb8a930 391 SUPERFAMILY SSF51905 317 378 1.81E-47 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS12670 35df1060f35ebb4f3d90df65adb8a930 391 PANTHER PTHR13847:SF180 1 373 9.6E-112 T 23-04-2016 DC74_RS12670 35df1060f35ebb4f3d90df65adb8a930 391 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 1 358 1.2E-114 T 23-04-2016 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 UniPathway: UPA00060 DC74_RS12670 35df1060f35ebb4f3d90df65adb8a930 391 PANTHER PTHR13847 1 373 9.6E-112 T 23-04-2016 DC74_RS12670 35df1060f35ebb4f3d90df65adb8a930 391 Gene3D G3DSA:3.30.9.10 205 315 6.6E-17 T 23-04-2016 DC74_RS35360 050d0a21801afab0c26ec43cd10415bd 421 SUPERFAMILY SSF53649 9 405 1.26E-94 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS35360 050d0a21801afab0c26ec43cd10415bd 421 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 23 360 5.7E-30 T 23-04-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 DC74_RS35360 050d0a21801afab0c26ec43cd10415bd 421 Gene3D G3DSA:3.40.720.10 9 302 4.3E-61 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 DC74_RS35360 050d0a21801afab0c26ec43cd10415bd 421 TIGRFAM TIGR02335 hydr_PhnA: phosphonoacetate hydrolase 10 406 1.4E-164 T 23-04-2016 IPR012710 Phosphonoacetate hydrolase GO:0047400 KEGG: 00440+3.11.1.2 DC74_RS18130 25367797b26893fd54b7d991e3561e9a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 6.12E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18130 25367797b26893fd54b7d991e3561e9a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.12E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18130 25367797b26893fd54b7d991e3561e9a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.12E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18130 25367797b26893fd54b7d991e3561e9a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.12E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18130 25367797b26893fd54b7d991e3561e9a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.12E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18130 25367797b26893fd54b7d991e3561e9a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.12E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18130 25367797b26893fd54b7d991e3561e9a 261 PANTHER PTHR24322 157 189 5.9E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18130 25367797b26893fd54b7d991e3561e9a 261 PANTHER PTHR24322 10 139 5.9E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18130 25367797b26893fd54b7d991e3561e9a 261 Gene3D G3DSA:3.40.50.720 3 258 5.9E-64 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18130 25367797b26893fd54b7d991e3561e9a 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 257 2.4E-49 T 23-04-2016 DC74_RS18130 25367797b26893fd54b7d991e3561e9a 261 SUPERFAMILY SSF51735 5 260 3.74E-65 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS17870 a85ab18af16059650014d1b7a1620af7 114 SMART SM00834 2 41 1.0E-13 T 23-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain DC74_RS17870 a85ab18af16059650014d1b7a1620af7 114 Pfam PF09723 Zinc ribbon domain 2 40 4.3E-13 T 23-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain DC74_RS17870 a85ab18af16059650014d1b7a1620af7 114 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 2.2E-19 T 23-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain DC74_RS17870 a85ab18af16059650014d1b7a1620af7 114 PANTHER PTHR34404 2 98 5.4E-27 T 23-04-2016 DC74_RS17870 a85ab18af16059650014d1b7a1620af7 114 PANTHER PTHR34404:SF2 2 98 5.4E-27 T 23-04-2016 DC74_RS18920 f05efd8e14d28364adbeb85b0cb99931 321 PANTHER PTHR11432:SF3 1 321 2.3E-103 T 23-04-2016 DC74_RS18920 f05efd8e14d28364adbeb85b0cb99931 321 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 3 320 22.23 T 23-04-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 DC74_RS18920 f05efd8e14d28364adbeb85b0cb99931 321 PANTHER PTHR11432 1 321 2.3E-103 T 23-04-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 DC74_RS18920 f05efd8e14d28364adbeb85b0cb99931 321 Pfam PF00146 NADH dehydrogenase 11 313 1.0E-100 T 23-04-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 DC74_RS30965 a841a3b55cabd8053d47ca2a7dea2320 182 Pfam PF13581 Histidine kinase-like ATPase domain 17 119 3.3E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS30965 a841a3b55cabd8053d47ca2a7dea2320 182 SUPERFAMILY SSF55874 32 118 3.68E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS16070 619cba0acae0c286f5cf751ff9fd9c66 376 PANTHER PTHR30137:SF2 24 370 2.8E-131 T 23-04-2016 DC74_RS16070 619cba0acae0c286f5cf751ff9fd9c66 376 PANTHER PTHR30137 24 370 2.8E-131 T 23-04-2016 DC74_RS16070 619cba0acae0c286f5cf751ff9fd9c66 376 Pfam PF00296 Luciferase-like monooxygenase 34 346 8.8E-44 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS16070 619cba0acae0c286f5cf751ff9fd9c66 376 Gene3D G3DSA:3.20.20.30 31 369 7.8E-91 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS16070 619cba0acae0c286f5cf751ff9fd9c66 376 SUPERFAMILY SSF51679 31 369 3.4E-78 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS16070 619cba0acae0c286f5cf751ff9fd9c66 376 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 32 370 1.3E-129 T 23-04-2016 IPR019949 Luciferase family oxidoreductase, group 1 DC74_RS25625 e76826ca9074b53d4ad5ab9a50bfc401 197 Gene3D G3DSA:3.40.109.10 13 193 2.0E-35 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS25625 e76826ca9074b53d4ad5ab9a50bfc401 197 SUPERFAMILY SSF55469 17 194 6.81E-37 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS25625 e76826ca9074b53d4ad5ab9a50bfc401 197 PANTHER PTHR23026:SF110 11 193 7.0E-85 T 23-04-2016 DC74_RS25625 e76826ca9074b53d4ad5ab9a50bfc401 197 PANTHER PTHR23026 11 193 7.0E-85 T 23-04-2016 DC74_RS25625 e76826ca9074b53d4ad5ab9a50bfc401 197 Pfam PF00881 Nitroreductase family 18 175 1.1E-13 T 23-04-2016 IPR029479 Nitroreductase DC74_RS30735 bf2b9b5f364ec3161f606a01c2b9294e 414 SUPERFAMILY SSF48452 186 371 8.34E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS30735 bf2b9b5f364ec3161f606a01c2b9294e 414 SUPERFAMILY SSF47413 6 72 5.32E-6 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS30735 bf2b9b5f364ec3161f606a01c2b9294e 414 Pfam PF13560 Helix-turn-helix domain 6 72 1.0E-8 T 23-04-2016 DC74_RS30735 bf2b9b5f364ec3161f606a01c2b9294e 414 Gene3D G3DSA:1.10.260.40 6 72 6.6E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS30735 bf2b9b5f364ec3161f606a01c2b9294e 414 Gene3D G3DSA:1.25.40.10 184 287 1.6E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS30735 bf2b9b5f364ec3161f606a01c2b9294e 414 Gene3D G3DSA:1.25.40.10 332 379 1.6E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20670 74a679962b26757e8f640f8a1695eda5 177 PANTHER PTHR36456 47 176 1.4E-29 T 23-04-2016 DC74_RS20670 74a679962b26757e8f640f8a1695eda5 177 Hamap MF_00630 UPF0232 protein . 1 163 29.203 T 23-04-2016 IPR023007 Uncharacterised protein family UPF0232, actinobacteria DC74_RS20670 74a679962b26757e8f640f8a1695eda5 177 Pfam PF05258 Protein of unknown function (DUF721) 62 151 2.8E-25 T 23-04-2016 IPR007922 Protein of unknown function DUF721/UPF0232 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 PRINTS PR00359 B-class P450 signature 93 104 5.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 PRINTS PR00359 B-class P450 signature 351 362 5.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 PRINTS PR00359 B-class P450 signature 342 351 5.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 PRINTS PR00359 B-class P450 signature 156 171 5.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 PRINTS PR00359 B-class P450 signature 275 286 5.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 PRINTS PR00359 B-class P450 signature 293 320 5.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 PRINTS PR00359 B-class P450 signature 194 216 5.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 PRINTS PR00359 B-class P450 signature 139 155 5.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 PRINTS PR00359 B-class P450 signature 321 336 5.7E-60 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 SUPERFAMILY SSF48264 11 404 3.41E-109 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 Pfam PF00067 Cytochrome P450 203 371 1.2E-24 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 PANTHER PTHR11712 7 404 2.0E-117 T 23-04-2016 DC74_RS06390 23576831b9a64af981e70839abdfd6ab 409 Gene3D G3DSA:1.10.630.10 5 404 1.2E-140 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS00615 2003a07639b6e2fe26a8fbfc27787a73 278 PANTHER PTHR30346 4 275 2.0E-61 T 23-04-2016 DC74_RS00615 2003a07639b6e2fe26a8fbfc27787a73 278 Pfam PF03466 LysR substrate binding domain 93 193 3.5E-11 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS00615 2003a07639b6e2fe26a8fbfc27787a73 278 Gene3D G3DSA:1.10.10.10 4 83 2.0E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00615 2003a07639b6e2fe26a8fbfc27787a73 278 SUPERFAMILY SSF53850 94 271 3.58E-17 T 23-04-2016 DC74_RS00615 2003a07639b6e2fe26a8fbfc27787a73 278 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.3E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00615 2003a07639b6e2fe26a8fbfc27787a73 278 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.3E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00615 2003a07639b6e2fe26a8fbfc27787a73 278 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.3E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00615 2003a07639b6e2fe26a8fbfc27787a73 278 SUPERFAMILY SSF46785 5 87 6.28E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00615 2003a07639b6e2fe26a8fbfc27787a73 278 PANTHER PTHR30346:SF0 4 275 2.0E-61 T 23-04-2016 DC74_RS00615 2003a07639b6e2fe26a8fbfc27787a73 278 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 8.6E-20 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS00615 2003a07639b6e2fe26a8fbfc27787a73 278 Gene3D G3DSA:3.40.190.10 105 188 1.2E-9 T 23-04-2016 DC74_RS00615 2003a07639b6e2fe26a8fbfc27787a73 278 Gene3D G3DSA:3.40.190.10 207 249 0.001 T 23-04-2016 DC74_RS11025 12cfee778ca7e7f2cd737d03d34c0f91 340 PANTHER PTHR16222 11 334 9.5E-60 T 23-04-2016 DC74_RS11025 12cfee778ca7e7f2cd737d03d34c0f91 340 Pfam PF03747 ADP-ribosylglycohydrolase 13 319 4.2E-56 T 23-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 DC74_RS11025 12cfee778ca7e7f2cd737d03d34c0f91 340 SUPERFAMILY SSF101478 11 227 6.28E-54 T 23-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 DC74_RS11025 12cfee778ca7e7f2cd737d03d34c0f91 340 SUPERFAMILY SSF101478 260 335 6.28E-54 T 23-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 DC74_RS11025 12cfee778ca7e7f2cd737d03d34c0f91 340 PANTHER PTHR16222:SF12 11 334 9.5E-60 T 23-04-2016 DC74_RS32415 f1bfaa570d90c489d348e1f31743a2be 305 SUPERFAMILY SSF53448 1 286 1.43E-80 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS32415 f1bfaa570d90c489d348e1f31743a2be 305 PANTHER PTHR22572 2 265 1.3E-132 T 23-04-2016 DC74_RS32415 f1bfaa570d90c489d348e1f31743a2be 305 Gene3D G3DSA:3.90.550.10 1 255 1.5E-62 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS32415 f1bfaa570d90c489d348e1f31743a2be 305 Pfam PF00483 Nucleotidyl transferase 2 235 1.8E-59 T 23-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 DC74_RS32415 f1bfaa570d90c489d348e1f31743a2be 305 PANTHER PTHR22572:SF105 2 265 1.3E-132 T 23-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 DC74_RS32415 f1bfaa570d90c489d348e1f31743a2be 305 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 2.2E-124 T 23-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 PANTHER PTHR11573:SF18 915 961 0.0 T 23-04-2016 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 PANTHER PTHR11573:SF18 37 266 0.0 T 23-04-2016 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 PANTHER PTHR11573:SF18 289 890 0.0 T 23-04-2016 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 Pfam PF02867 Ribonucleotide reductase, barrel domain 158 697 2.8E-146 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 PRINTS PR01183 Ribonucleotide reductase large chain signature 360 371 9.5E-16 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 PRINTS PR01183 Ribonucleotide reductase large chain signature 464 487 9.5E-16 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 PRINTS PR01183 Ribonucleotide reductase large chain signature 436 458 9.5E-16 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 PRINTS PR01183 Ribonucleotide reductase large chain signature 398 421 9.5E-16 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 PRINTS PR01183 Ribonucleotide reductase large chain signature 543 570 9.5E-16 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 PRINTS PR01183 Ribonucleotide reductase large chain signature 233 252 9.5E-16 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 97 707 1.6E-185 T 23-04-2016 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 Gene3D G3DSA:3.20.70.20 543 589 1.5E-97 T 23-04-2016 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 Gene3D G3DSA:3.20.70.20 656 701 1.5E-97 T 23-04-2016 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 Gene3D G3DSA:3.20.70.20 68 484 1.5E-97 T 23-04-2016 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 54 137 1.5E-19 T 23-04-2016 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 SUPERFAMILY SSF51998 630 708 1.56E-131 T 23-04-2016 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 SUPERFAMILY SSF51998 158 595 1.56E-131 T 23-04-2016 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 PANTHER PTHR11573 915 961 0.0 T 23-04-2016 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 PANTHER PTHR11573 37 266 0.0 T 23-04-2016 DC74_RS28935 8d5f09f61516566b03d07932ffbe76f6 961 PANTHER PTHR11573 289 890 0.0 T 23-04-2016 DC74_RS38150 40d3c9b1c0dd66def2f193b1b9c7267d 248 Pfam PF01636 Phosphotransferase enzyme family 17 197 8.9E-18 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS38150 40d3c9b1c0dd66def2f193b1b9c7267d 248 Gene3D G3DSA:3.90.1200.10 62 221 2.7E-24 T 23-04-2016 DC74_RS38150 40d3c9b1c0dd66def2f193b1b9c7267d 248 PANTHER PTHR21310 4 233 2.4E-12 T 23-04-2016 DC74_RS38150 40d3c9b1c0dd66def2f193b1b9c7267d 248 SUPERFAMILY SSF56112 12 219 5.98E-26 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS33795 e8f0f66dc5968235ef049cd488f5120e 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 276 1.6E-26 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS33795 e8f0f66dc5968235ef049cd488f5120e 292 PANTHER PTHR30465:SF2 6 288 1.6E-91 T 23-04-2016 DC74_RS33795 e8f0f66dc5968235ef049cd488f5120e 292 Gene3D G3DSA:1.10.3720.10 82 285 9.5E-26 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS33795 e8f0f66dc5968235ef049cd488f5120e 292 PANTHER PTHR30465 6 288 1.6E-91 T 23-04-2016 DC74_RS33795 e8f0f66dc5968235ef049cd488f5120e 292 SUPERFAMILY SSF161098 82 270 4.32E-27 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS35550 310da4b35654e107426d39b54ed6f676 349 SUPERFAMILY SSF50998 236 301 7.98E-26 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS35550 310da4b35654e107426d39b54ed6f676 349 SUPERFAMILY SSF50998 23 198 7.98E-26 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS35550 310da4b35654e107426d39b54ed6f676 349 Pfam PF13360 PQQ-like domain 22 188 3.3E-18 T 23-04-2016 IPR002372 Pyrrolo-quinoline quinone repeat DC74_RS35550 310da4b35654e107426d39b54ed6f676 349 Gene3D G3DSA:2.140.10.10 22 294 2.6E-26 T 23-04-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain DC74_RS33090 5808ea60f037e85b3945dbfaadecc998 271 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 3 243 3.7E-52 T 23-04-2016 IPR018713 Domain of unknown function DUF2236 DC74_RS33090 5808ea60f037e85b3945dbfaadecc998 271 PANTHER PTHR36151 1 267 1.1E-47 T 23-04-2016 DC74_RS33090 5808ea60f037e85b3945dbfaadecc998 271 PANTHER PTHR36151:SF3 1 267 1.1E-47 T 23-04-2016 DC74_RS07330 a78b0ef64af6f2db442717940e960e7d 171 SUPERFAMILY SSF56524 26 164 1.44E-20 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS07330 a78b0ef64af6f2db442717940e960e7d 171 Pfam PF00174 Oxidoreductase molybdopterin binding domain 28 164 1.9E-9 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS07330 a78b0ef64af6f2db442717940e960e7d 171 Gene3D G3DSA:3.90.420.10 28 138 5.3E-13 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS23910 e1cf7445016ccbf367c118bfaa0d6fb1 255 PANTHER PTHR30390:SF6 7 255 9.3E-59 T 23-04-2016 DC74_RS23910 e1cf7445016ccbf367c118bfaa0d6fb1 255 Gene3D G3DSA:3.40.50.10490 12 250 4.1E-71 T 23-04-2016 DC74_RS23910 e1cf7445016ccbf367c118bfaa0d6fb1 255 Pfam PF13580 SIS domain 13 150 2.0E-39 T 23-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 DC74_RS23910 e1cf7445016ccbf367c118bfaa0d6fb1 255 Hamap MF_01240 UPF0309 protein . 10 254 38.887 T 23-04-2016 IPR022951 Uncharacterised protein family UPF0309 DC74_RS23910 e1cf7445016ccbf367c118bfaa0d6fb1 255 PANTHER PTHR30390 7 255 9.3E-59 T 23-04-2016 DC74_RS23910 e1cf7445016ccbf367c118bfaa0d6fb1 255 SUPERFAMILY SSF53697 11 214 2.89E-23 T 23-04-2016 DC74_RS39165 c1420d1ae1001e25eb6ff79bd410eeba 428 Gene3D G3DSA:3.40.50.980 62 205 7.1E-4 T 23-04-2016 DC74_RS39165 c1420d1ae1001e25eb6ff79bd410eeba 428 PANTHER PTHR36932:SF1 4 324 4.6E-22 T 23-04-2016 DC74_RS39165 c1420d1ae1001e25eb6ff79bd410eeba 428 Pfam PF00501 AMP-binding enzyme 60 268 2.4E-5 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS39165 c1420d1ae1001e25eb6ff79bd410eeba 428 SUPERFAMILY SSF56801 25 420 2.62E-22 T 23-04-2016 DC74_RS39165 c1420d1ae1001e25eb6ff79bd410eeba 428 PANTHER PTHR36932 4 324 4.6E-22 T 23-04-2016 DC74_RS39165 c1420d1ae1001e25eb6ff79bd410eeba 428 ProSitePatterns PS00455 Putative AMP-binding domain signature. 66 77 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 Gene3D G3DSA:1.10.630.10 3 406 1.4E-105 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PANTHER PTHR24286:SF32 40 407 1.3E-136 T 23-04-2016 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PRINTS PR00385 P450 superfamily signature 344 353 2.0E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PRINTS PR00385 P450 superfamily signature 268 279 2.0E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PRINTS PR00385 P450 superfamily signature 353 364 2.0E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PRINTS PR00385 P450 superfamily signature 233 250 2.0E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 Pfam PF00067 Cytochrome P450 36 374 4.7E-29 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 SUPERFAMILY SSF48264 13 405 1.83E-90 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 23-04-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PRINTS PR00359 B-class P450 signature 187 209 2.4E-40 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PRINTS PR00359 B-class P450 signature 285 312 2.4E-40 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PRINTS PR00359 B-class P450 signature 313 328 2.4E-40 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PRINTS PR00359 B-class P450 signature 344 353 2.4E-40 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PRINTS PR00359 B-class P450 signature 353 364 2.4E-40 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PRINTS PR00359 B-class P450 signature 126 142 2.4E-40 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PRINTS PR00359 B-class P450 signature 268 279 2.4E-40 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PRINTS PR00359 B-class P450 signature 143 158 2.4E-40 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS02695 8b1d5db8b382af1ba627299eb68123f9 407 PANTHER PTHR24286 40 407 1.3E-136 T 23-04-2016 DC74_RS23680 7ba7f04193665cbbc60e3ca9ad4af273 336 Pfam PF01032 FecCD transport family 22 331 2.2E-89 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS23680 7ba7f04193665cbbc60e3ca9ad4af273 336 PANTHER PTHR30472 6 336 1.6E-117 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 DC74_RS23680 7ba7f04193665cbbc60e3ca9ad4af273 336 Gene3D G3DSA:1.10.3470.10 8 333 1.5E-99 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS23680 7ba7f04193665cbbc60e3ca9ad4af273 336 SUPERFAMILY SSF81345 5 332 6.8E-78 T 23-04-2016 IPR029022 ABC transporter, BtuC-like DC74_RS23680 7ba7f04193665cbbc60e3ca9ad4af273 336 PANTHER PTHR30472:SF31 6 336 1.6E-117 T 23-04-2016 DC74_RS15155 5cfce6e49cff4b847b29eebd91443f13 144 SUPERFAMILY SSF81301 8 119 4.09E-35 T 23-04-2016 DC74_RS15155 5cfce6e49cff4b847b29eebd91443f13 144 PANTHER PTHR21043 6 123 3.5E-34 T 23-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS DC74_RS15155 5cfce6e49cff4b847b29eebd91443f13 144 Pfam PF02410 Ribosomal silencing factor during starvation 16 109 4.8E-22 T 23-04-2016 DC74_RS15155 5cfce6e49cff4b847b29eebd91443f13 144 Gene3D G3DSA:3.30.460.10 8 113 1.9E-32 T 23-04-2016 DC74_RS15155 5cfce6e49cff4b847b29eebd91443f13 144 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 110 22.801 T 23-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS DC74_RS15155 5cfce6e49cff4b847b29eebd91443f13 144 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 12 109 1.2E-29 T 23-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 149 0.0084 T 23-04-2016 DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 Gene3D G3DSA:3.40.50.720 3 249 4.4E-79 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 SUPERFAMILY SSF51735 7 249 3.36E-74 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 248 3.0E-57 T 23-04-2016 DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.5E-37 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.5E-37 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.5E-37 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 2.5E-37 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.5E-37 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.5E-37 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 3.2E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 3.2E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.2E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 PANTHER PTHR24322 158 193 2.8E-53 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS38400 37a43a06ffda3e2022197c63eeda270d 256 PANTHER PTHR24322 12 142 2.8E-53 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS35720 af09adf138f5b0c2a3f8d9777428a170 186 SUPERFAMILY SSF55144 32 177 4.19E-14 T 23-04-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase DC74_RS35720 af09adf138f5b0c2a3f8d9777428a170 186 Pfam PF13563 2'-5' RNA ligase superfamily 23 166 1.4E-21 T 23-04-2016 DC74_RS35720 af09adf138f5b0c2a3f8d9777428a170 186 Gene3D G3DSA:3.90.1140.10 22 177 1.2E-10 T 23-04-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase DC74_RS28805 ef83d51ab626a6e0084be22b51d9f3b9 311 Gene3D G3DSA:1.10.3720.10 63 275 3.5E-43 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28805 ef83d51ab626a6e0084be22b51d9f3b9 311 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 63 164 3.1E-18 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 DC74_RS28805 ef83d51ab626a6e0084be22b51d9f3b9 311 PANTHER PTHR30614 66 280 1.2E-63 T 23-04-2016 DC74_RS28805 ef83d51ab626a6e0084be22b51d9f3b9 311 SUPERFAMILY SSF161098 64 260 4.45E-39 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS28805 ef83d51ab626a6e0084be22b51d9f3b9 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 273 4.4E-21 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS10870 5eecfb8df350b01d1d3ac4f71c55d346 268 Pfam PF07920 Protein of unknown function (DUF1684) 128 263 2.6E-33 T 23-04-2016 IPR012467 Protein of unknown function DUF1684 DC74_RS10870 5eecfb8df350b01d1d3ac4f71c55d346 268 PANTHER PTHR41913:SF1 7 268 3.6E-60 T 23-04-2016 DC74_RS10870 5eecfb8df350b01d1d3ac4f71c55d346 268 PANTHER PTHR41913 7 268 3.6E-60 T 23-04-2016 DC74_RS25115 2522c102846f2a1a704092fd304b87b8 308 PANTHER PTHR31126:SF21 48 129 3.0E-45 T 23-04-2016 DC74_RS25115 2522c102846f2a1a704092fd304b87b8 308 PANTHER PTHR31126:SF21 165 306 3.0E-45 T 23-04-2016 DC74_RS25115 2522c102846f2a1a704092fd304b87b8 308 PANTHER PTHR31126 48 129 3.0E-45 T 23-04-2016 DC74_RS25115 2522c102846f2a1a704092fd304b87b8 308 PANTHER PTHR31126 165 306 3.0E-45 T 23-04-2016 DC74_RS25115 2522c102846f2a1a704092fd304b87b8 308 Pfam PF13350 Tyrosine phosphatase family 52 306 2.7E-65 T 23-04-2016 IPR026893 Tyrosine/serine-protein phosphatase IphP-type DC74_RS25115 2522c102846f2a1a704092fd304b87b8 308 Gene3D G3DSA:3.90.190.10 53 136 3.3E-16 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS25115 2522c102846f2a1a704092fd304b87b8 308 Gene3D G3DSA:3.90.190.10 174 246 3.3E-16 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS25115 2522c102846f2a1a704092fd304b87b8 308 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 197 207 - T 23-04-2016 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 DC74_RS25115 2522c102846f2a1a704092fd304b87b8 308 SUPERFAMILY SSF52799 52 306 1.18E-48 T 23-04-2016 IPR029021 Protein-tyrosine phosphatase-like DC74_RS21405 5bc9b98e91589a5d8bebbe176b044674 162 Pfam PF02627 Carboxymuconolactone decarboxylase family 28 98 1.6E-7 T 23-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DC74_RS21405 5bc9b98e91589a5d8bebbe176b044674 162 Gene3D G3DSA:1.20.1290.10 17 149 1.9E-28 T 23-04-2016 IPR029032 AhpD-like DC74_RS21405 5bc9b98e91589a5d8bebbe176b044674 162 SUPERFAMILY SSF69118 16 146 1.38E-23 T 23-04-2016 IPR029032 AhpD-like DC74_RS12590 84b83a09455ae52456b2c34bd86e4141 341 SUPERFAMILY SSF52540 30 291 7.51E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12590 84b83a09455ae52456b2c34bd86e4141 341 Gene3D G3DSA:3.40.50.300 33 193 6.8E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12590 84b83a09455ae52456b2c34bd86e4141 341 PANTHER PTHR11603 3 319 7.9E-126 T 23-04-2016 DC74_RS12590 84b83a09455ae52456b2c34bd86e4141 341 PIRSF PIRSF002849 2 321 4.0E-128 T 23-04-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted DC74_RS12590 84b83a09455ae52456b2c34bd86e4141 341 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 47 176 5.2E-65 T 23-04-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 DC74_RS12590 84b83a09455ae52456b2c34bd86e4141 341 Gene3D G3DSA:1.10.8.300 209 315 1.5E-33 T 23-04-2016 DC74_RS13620 f83d609e6518bcf3bff31801d5dffe9f 336 Pfam PF00296 Luciferase-like monooxygenase 17 315 1.2E-61 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS13620 f83d609e6518bcf3bff31801d5dffe9f 336 PANTHER PTHR30011 15 321 3.3E-95 T 23-04-2016 DC74_RS13620 f83d609e6518bcf3bff31801d5dffe9f 336 PANTHER PTHR30011:SF4 15 321 3.3E-95 T 23-04-2016 DC74_RS13620 f83d609e6518bcf3bff31801d5dffe9f 336 SUPERFAMILY SSF51679 1 327 1.25E-57 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS13620 f83d609e6518bcf3bff31801d5dffe9f 336 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 321 4.3E-133 T 23-04-2016 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- DC74_RS13620 f83d609e6518bcf3bff31801d5dffe9f 336 Gene3D G3DSA:3.20.20.30 1 334 1.1E-64 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 PANTHER PTHR10992:SF305 10 165 2.4E-108 T 23-04-2016 DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 PANTHER PTHR10992:SF305 204 320 2.4E-108 T 23-04-2016 DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 Pfam PF00561 alpha/beta hydrolase fold 26 306 2.0E-28 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 Gene3D G3DSA:3.40.50.1820 4 321 1.4E-89 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 SUPERFAMILY SSF53474 5 321 3.98E-76 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 PANTHER PTHR10992 10 165 2.4E-108 T 23-04-2016 DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 PANTHER PTHR10992 204 320 2.4E-108 T 23-04-2016 DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 PRINTS PR00412 Epoxide hydrolase signature 295 317 2.9E-35 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 PRINTS PR00412 Epoxide hydrolase signature 98 111 2.9E-35 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 PRINTS PR00412 Epoxide hydrolase signature 32 50 2.9E-35 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 PRINTS PR00412 Epoxide hydrolase signature 257 273 2.9E-35 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 PRINTS PR00412 Epoxide hydrolase signature 112 125 2.9E-35 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS08540 61fbdd41526a0b05fa2292bfa4b31e06 323 PRINTS PR00412 Epoxide hydrolase signature 52 67 2.9E-35 T 23-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 DC74_RS33525 92fb638dd3e74409d164103fe7e9fbbe 249 Pfam PF08223 PaaX-like protein C-terminal domain 91 234 3.3E-13 T 23-04-2016 IPR013225 PaaX-like, C-terminal UniPathway: UPA00930 DC74_RS33525 92fb638dd3e74409d164103fe7e9fbbe 249 Pfam PF07848 PaaX-like protein 13 73 1.1E-13 T 23-04-2016 IPR012906 PaaX-like, N-terminal UniPathway: UPA00930 DC74_RS33525 92fb638dd3e74409d164103fe7e9fbbe 249 PANTHER PTHR30319 1 238 2.6E-53 T 23-04-2016 DC74_RS33525 92fb638dd3e74409d164103fe7e9fbbe 249 PANTHER PTHR30319:SF1 1 238 2.6E-53 T 23-04-2016 DC74_RS05775 8c0bf3b55b8d79637992dda071047660 171 Gene3D G3DSA:1.10.10.10 18 153 3.2E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05775 8c0bf3b55b8d79637992dda071047660 171 PANTHER PTHR33164 45 162 3.2E-22 T 23-04-2016 DC74_RS05775 8c0bf3b55b8d79637992dda071047660 171 PANTHER PTHR33164:SF10 45 162 3.2E-22 T 23-04-2016 DC74_RS05775 8c0bf3b55b8d79637992dda071047660 171 SUPERFAMILY SSF46785 27 151 4.85E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05775 8c0bf3b55b8d79637992dda071047660 171 SMART SM00347 38 138 4.5E-16 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS05775 8c0bf3b55b8d79637992dda071047660 171 Pfam PF12802 MarR family 45 101 6.4E-13 T 23-04-2016 DC74_RS23890 98ea6a1601e9700846d1b01db501b373 207 PANTHER PTHR30328:SF29 1 201 3.1E-46 T 23-04-2016 DC74_RS23890 98ea6a1601e9700846d1b01db501b373 207 PANTHER PTHR30328 1 201 3.1E-46 T 23-04-2016 DC74_RS23890 98ea6a1601e9700846d1b01db501b373 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 7.4E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS23890 98ea6a1601e9700846d1b01db501b373 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.2E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS23890 98ea6a1601e9700846d1b01db501b373 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.2E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS23890 98ea6a1601e9700846d1b01db501b373 207 SUPERFAMILY SSF46689 13 92 4.32E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS23890 98ea6a1601e9700846d1b01db501b373 207 Gene3D G3DSA:1.10.357.10 8 205 3.3E-30 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS04420 6f565e22be19706f7708c5a9ec184d29 451 PANTHER PTHR22935 41 370 4.2E-63 T 23-04-2016 DC74_RS04420 6f565e22be19706f7708c5a9ec184d29 451 Pfam PF00144 Beta-lactamase 81 371 2.3E-56 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS04420 6f565e22be19706f7708c5a9ec184d29 451 SUPERFAMILY SSF56601 71 394 4.51E-72 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS04420 6f565e22be19706f7708c5a9ec184d29 451 Gene3D G3DSA:3.40.710.10 69 386 2.2E-73 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS09030 d888ac1ba997061f8cde001becd09dc7 164 Pfam PF04134 Protein of unknown function, DUF393 22 126 6.7E-10 T 23-04-2016 IPR007263 Protein of unknown function DUF393 DC74_RS03630 8ff369b2736d51b29d43473648496cab 366 SUPERFAMILY SSF81606 151 354 1.99E-5 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS03630 8ff369b2736d51b29d43473648496cab 366 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 164 358 1.7E-41 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS03630 8ff369b2736d51b29d43473648496cab 366 PANTHER PTHR21021 111 366 2.0E-32 T 23-04-2016 DC74_RS03630 8ff369b2736d51b29d43473648496cab 366 PANTHER PTHR21021 19 39 2.0E-32 T 23-04-2016 DC74_RS03630 8ff369b2736d51b29d43473648496cab 366 SMART SM00331 136 358 4.0E-28 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS24705 cf4666c04000d7e23e5abba9d9c8cca9 199 PANTHER PTHR40037:SF1 2 178 9.0E-43 T 23-04-2016 DC74_RS24705 cf4666c04000d7e23e5abba9d9c8cca9 199 Gene3D G3DSA:3.90.1140.10 8 177 4.6E-26 T 23-04-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase DC74_RS24705 cf4666c04000d7e23e5abba9d9c8cca9 199 PANTHER PTHR40037 2 178 9.0E-43 T 23-04-2016 DC74_RS24705 cf4666c04000d7e23e5abba9d9c8cca9 199 Pfam PF13563 2'-5' RNA ligase superfamily 13 160 1.2E-23 T 23-04-2016 DC74_RS24705 cf4666c04000d7e23e5abba9d9c8cca9 199 SUPERFAMILY SSF55144 5 174 8.89E-33 T 23-04-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase DC74_RS33745 5f6315fd42809027d9bc30da94fda41a 297 SUPERFAMILY SSF47413 35 86 3.56E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS33745 5f6315fd42809027d9bc30da94fda41a 297 Gene3D G3DSA:1.10.260.40 9 86 1.6E-19 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS33745 5f6315fd42809027d9bc30da94fda41a 297 PANTHER PTHR35010 11 296 4.9E-85 T 23-04-2016 DC74_RS33745 5f6315fd42809027d9bc30da94fda41a 297 PANTHER PTHR35010:SF2 11 296 4.9E-85 T 23-04-2016 DC74_RS33745 5f6315fd42809027d9bc30da94fda41a 297 SMART SM00530 14 87 3.8E-9 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS33745 5f6315fd42809027d9bc30da94fda41a 297 Pfam PF13560 Helix-turn-helix domain 10 90 1.3E-18 T 23-04-2016 DC74_RS06335 355cc25e41bc08708a42e911e83f0bd1 240 PANTHER PTHR30328:SF17 1 134 5.5E-26 T 23-04-2016 DC74_RS06335 355cc25e41bc08708a42e911e83f0bd1 240 Gene3D G3DSA:1.10.357.10 86 231 2.4E-50 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS06335 355cc25e41bc08708a42e911e83f0bd1 240 Gene3D G3DSA:1.10.10.60 11 81 2.5E-19 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06335 355cc25e41bc08708a42e911e83f0bd1 240 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 89 188 8.4E-11 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS06335 355cc25e41bc08708a42e911e83f0bd1 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 5.8E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS06335 355cc25e41bc08708a42e911e83f0bd1 240 SUPERFAMILY SSF48498 90 232 2.78E-27 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS06335 355cc25e41bc08708a42e911e83f0bd1 240 SUPERFAMILY SSF46689 23 84 4.46E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06335 355cc25e41bc08708a42e911e83f0bd1 240 PANTHER PTHR30328 1 134 5.5E-26 T 23-04-2016 DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 PANTHER PTHR26402 5 204 1.4E-102 T 23-04-2016 DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 SMART SM00421 141 198 3.2E-23 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 198 4.8E-16 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 3.7E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 3.7E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 3.7E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 SMART SM00448 5 118 2.9E-28 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 Gene3D G3DSA:3.40.50.2300 3 146 3.9E-38 T 23-04-2016 DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 Pfam PF00072 Response regulator receiver domain 8 118 1.2E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 SUPERFAMILY SSF46894 128 204 1.29E-20 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 SUPERFAMILY SSF52172 4 132 8.54E-33 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 PANTHER PTHR26402:SF137 5 204 1.4E-102 T 23-04-2016 DC74_RS25900 6965a91de7000106a2b088e0436c1379 204 Gene3D G3DSA:1.10.10.10 147 204 8.0E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS04535 710058cd267f3101356fd0ba76b49ab1 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 45 56 1.2E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04535 710058cd267f3101356fd0ba76b49ab1 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 119 138 1.2E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04535 710058cd267f3101356fd0ba76b49ab1 269 Pfam PF00106 short chain dehydrogenase 2 156 1.3E-32 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04535 710058cd267f3101356fd0ba76b49ab1 269 SUPERFAMILY SSF51735 1 228 9.36E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04535 710058cd267f3101356fd0ba76b49ab1 269 Gene3D G3DSA:3.40.50.720 1 203 3.6E-43 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04535 710058cd267f3101356fd0ba76b49ab1 269 PANTHER PTHR24322 119 151 7.0E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04535 710058cd267f3101356fd0ba76b49ab1 269 PANTHER PTHR24322 3 103 7.0E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04535 710058cd267f3101356fd0ba76b49ab1 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 157 3.3E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04535 710058cd267f3101356fd0ba76b49ab1 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 138 3.3E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04535 710058cd267f3101356fd0ba76b49ab1 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 45 56 3.3E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04535 710058cd267f3101356fd0ba76b49ab1 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 109 3.3E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS04535 710058cd267f3101356fd0ba76b49ab1 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 106 134 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 PANTHER PTHR24319 15 247 2.9E-102 T 23-04-2016 DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 PANTHER PTHR24319:SF32 15 247 2.9E-102 T 23-04-2016 DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 5.2E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 5.2E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 5.2E-5 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 Pfam PF00106 short chain dehydrogenase 16 198 1.1E-48 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.8E-22 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 SUPERFAMILY SSF51735 15 237 1.51E-60 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 191 0.0045 T 23-04-2016 DC74_RS19365 51ad830d1fdd189daf28b2592b3c73bc 261 Gene3D G3DSA:3.40.50.720 15 246 3.6E-62 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS33790 585922973cfe62e005f6f0f67d56c1da 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 317 2.4E-36 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS33790 585922973cfe62e005f6f0f67d56c1da 321 Gene3D G3DSA:1.10.3720.10 90 310 7.1E-15 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS33790 585922973cfe62e005f6f0f67d56c1da 321 SUPERFAMILY SSF161098 93 301 9.03E-13 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS33790 585922973cfe62e005f6f0f67d56c1da 321 PANTHER PTHR30465:SF24 1 319 1.2E-115 T 23-04-2016 DC74_RS33790 585922973cfe62e005f6f0f67d56c1da 321 PANTHER PTHR30465 1 319 1.2E-115 T 23-04-2016 DC74_RS24995 c5b18a1f1e03bd691c83df2f7c7f9c39 228 PANTHER PTHR26402:SF50 5 227 6.0E-100 T 23-04-2016 DC74_RS24995 c5b18a1f1e03bd691c83df2f7c7f9c39 228 SUPERFAMILY SSF52172 7 176 4.69E-41 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS24995 c5b18a1f1e03bd691c83df2f7c7f9c39 228 SMART SM00448 5 115 6.4E-40 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS24995 c5b18a1f1e03bd691c83df2f7c7f9c39 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 1.0E-24 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS24995 c5b18a1f1e03bd691c83df2f7c7f9c39 228 Gene3D G3DSA:1.10.10.10 127 226 8.0E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24995 c5b18a1f1e03bd691c83df2f7c7f9c39 228 Pfam PF00072 Response regulator receiver domain 8 115 1.9E-28 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS24995 c5b18a1f1e03bd691c83df2f7c7f9c39 228 Gene3D G3DSA:3.40.50.2300 7 126 1.3E-40 T 23-04-2016 DC74_RS24995 c5b18a1f1e03bd691c83df2f7c7f9c39 228 PANTHER PTHR26402 5 227 6.0E-100 T 23-04-2016 DC74_RS24995 c5b18a1f1e03bd691c83df2f7c7f9c39 228 SMART SM00862 148 224 9.1E-23 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS34905 c572efc361ab352473d0c7d637d35970 64 Pfam PF14013 MT0933-like antitoxin protein 4 52 4.2E-19 T 23-04-2016 IPR028037 Antitoxin Rv0909/MT0933 DC74_RS26755 f1fe002bf7163911ae0535cc8f180cc0 418 Gene3D G3DSA:3.50.50.60 3 169 7.0E-10 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS26755 f1fe002bf7163911ae0535cc8f180cc0 418 Gene3D G3DSA:3.50.50.60 281 362 7.0E-10 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS26755 f1fe002bf7163911ae0535cc8f180cc0 418 SUPERFAMILY SSF51905 2 164 7.34E-17 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS26755 f1fe002bf7163911ae0535cc8f180cc0 418 SUPERFAMILY SSF51905 289 364 7.34E-17 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS26755 f1fe002bf7163911ae0535cc8f180cc0 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.7E-5 T 23-04-2016 DC74_RS26755 f1fe002bf7163911ae0535cc8f180cc0 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 325 2.7E-5 T 23-04-2016 DC74_RS18865 6d5a5eccf053c3b80d6d0bab43fca634 220 PANTHER PTHR15020 1 218 1.6E-40 T 23-04-2016 DC74_RS18865 6d5a5eccf053c3b80d6d0bab43fca634 220 Gene3D G3DSA:3.40.50.720 1 208 1.4E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18865 6d5a5eccf053c3b80d6d0bab43fca634 220 Pfam PF13460 NAD(P)H-binding 7 194 4.8E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18865 6d5a5eccf053c3b80d6d0bab43fca634 220 SUPERFAMILY SSF51735 1 208 1.78E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10625 92f8b4961f6c1c9b61d9804978c6e0e1 422 PANTHER PTHR30480 53 421 2.6E-114 T 23-04-2016 DC74_RS10625 92f8b4961f6c1c9b61d9804978c6e0e1 422 Pfam PF07075 Protein of unknown function (DUF1343) 60 421 1.2E-128 T 23-04-2016 IPR008302 Uncharacterised conserved protein UCP016719 DC74_RS10625 92f8b4961f6c1c9b61d9804978c6e0e1 422 PIRSF PIRSF016719 4 422 3.3E-147 T 23-04-2016 IPR008302 Uncharacterised conserved protein UCP016719 DC74_RS10625 92f8b4961f6c1c9b61d9804978c6e0e1 422 PANTHER PTHR30480:SF3 53 421 2.6E-114 T 23-04-2016 DC74_RS10085 f6a22d2bfc25ada6d05862d7398747ee 374 SUPERFAMILY SSF46589 29 115 3.77E-13 T 23-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 DC74_RS10085 f6a22d2bfc25ada6d05862d7398747ee 374 PANTHER PTHR11538 309 372 8.9E-97 T 23-04-2016 DC74_RS10085 f6a22d2bfc25ada6d05862d7398747ee 374 PANTHER PTHR11538 109 291 8.9E-97 T 23-04-2016 DC74_RS10085 f6a22d2bfc25ada6d05862d7398747ee 374 Pfam PF01409 tRNA synthetases class II core domain (F) 109 369 1.8E-103 T 23-04-2016 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 DC74_RS10085 f6a22d2bfc25ada6d05862d7398747ee 374 SUPERFAMILY SSF55681 109 371 6.53E-76 T 23-04-2016 DC74_RS10085 f6a22d2bfc25ada6d05862d7398747ee 374 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 37 104 1.9E-14 T 23-04-2016 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 DC74_RS10085 f6a22d2bfc25ada6d05862d7398747ee 374 Gene3D G3DSA:3.30.930.10 26 371 5.5E-119 T 23-04-2016 DC74_RS10085 f6a22d2bfc25ada6d05862d7398747ee 374 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 69 368 1.3E-88 T 23-04-2016 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 DC74_RS10085 f6a22d2bfc25ada6d05862d7398747ee 374 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 25 370 45.613 T 23-04-2016 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 DC74_RS26810 b1cb8867c9137436d2206c5abeadbe56 484 Pfam PF00905 Penicillin binding protein transpeptidase domain 155 479 1.1E-56 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 DC74_RS26810 b1cb8867c9137436d2206c5abeadbe56 484 SUPERFAMILY SSF56601 95 481 1.04E-78 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS26810 b1cb8867c9137436d2206c5abeadbe56 484 PANTHER PTHR30627 26 481 7.8E-142 T 23-04-2016 DC74_RS26810 b1cb8867c9137436d2206c5abeadbe56 484 Gene3D G3DSA:3.40.710.10 143 481 4.3E-84 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS26810 b1cb8867c9137436d2206c5abeadbe56 484 Gene3D G3DSA:3.90.1310.10 73 142 4.6E-5 T 23-04-2016 DC74_RS26810 b1cb8867c9137436d2206c5abeadbe56 484 PANTHER PTHR30627:SF3 26 481 7.8E-142 T 23-04-2016 DC74_RS15405 54155861ff22410a0a149322a3e7fff7 231 SUPERFAMILY SSF52833 10 161 2.42E-18 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS15405 54155861ff22410a0a149322a3e7fff7 231 Gene3D G3DSA:3.40.30.10 6 148 1.8E-10 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS38235 70b250f8ac109c41a006c59c4b867aff 89 Pfam PF04226 Transglycosylase associated protein 33 82 1.2E-8 T 23-04-2016 IPR007341 Transglycosylase-associated protein GO:0016021 DC74_RS38235 70b250f8ac109c41a006c59c4b867aff 89 PANTHER PTHR33884 1 88 4.0E-22 T 23-04-2016 DC74_RS34480 d46dc04adbf5985ee084d0a4460223b1 223 SUPERFAMILY SSF53335 11 216 4.11E-37 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS34480 d46dc04adbf5985ee084d0a4460223b1 223 Pfam PF13649 Methyltransferase domain 48 141 6.9E-15 T 23-04-2016 DC74_RS34480 d46dc04adbf5985ee084d0a4460223b1 223 Gene3D G3DSA:3.40.50.150 27 221 2.1E-37 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS34480 d46dc04adbf5985ee084d0a4460223b1 223 PANTHER PTHR10108 14 184 1.1E-17 T 23-04-2016 DC74_RS22430 00b4c3fdbe5b61b11168857440eb5184 335 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 36 217 4.6E-43 T 23-04-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 DC74_RS22430 00b4c3fdbe5b61b11168857440eb5184 335 Gene3D G3DSA:3.40.50.620 31 197 8.2E-14 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS22430 00b4c3fdbe5b61b11168857440eb5184 335 SUPERFAMILY SSF52402 36 246 3.53E-46 T 23-04-2016 DC74_RS22430 00b4c3fdbe5b61b11168857440eb5184 335 Pfam PF09179 TilS substrate binding domain 263 330 1.3E-11 T 23-04-2016 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 DC74_RS22430 00b4c3fdbe5b61b11168857440eb5184 335 PANTHER PTHR11807 36 307 2.6E-48 T 23-04-2016 DC74_RS22430 00b4c3fdbe5b61b11168857440eb5184 335 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 14 324 19.889 T 23-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 DC74_RS22430 00b4c3fdbe5b61b11168857440eb5184 335 SUPERFAMILY SSF82829 226 330 1.31E-16 T 23-04-2016 DC74_RS22430 00b4c3fdbe5b61b11168857440eb5184 335 PANTHER PTHR11807:SF2 36 307 2.6E-48 T 23-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 DC74_RS22430 00b4c3fdbe5b61b11168857440eb5184 335 Pfam PF01171 PP-loop family 36 214 7.2E-38 T 23-04-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal DC74_RS00730 226eeb37bd2f1827a3ef0d4fb6227092 199 SUPERFAMILY SSF52218 11 190 9.0E-41 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS00730 226eeb37bd2f1827a3ef0d4fb6227092 199 Pfam PF03358 NADPH-dependent FMN reductase 58 130 7.2E-10 T 23-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 DC74_RS00730 226eeb37bd2f1827a3ef0d4fb6227092 199 Gene3D G3DSA:3.40.50.360 10 189 2.6E-53 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS00730 226eeb37bd2f1827a3ef0d4fb6227092 199 PANTHER PTHR30546 11 194 4.8E-26 T 23-04-2016 DC74_RS00730 226eeb37bd2f1827a3ef0d4fb6227092 199 PANTHER PTHR30546:SF0 11 194 4.8E-26 T 23-04-2016 DC74_RS05150 1740721e2cb82ff7a2ffba82a47ec590 400 SMART SM00191 247 297 17.0 T 23-04-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 DC74_RS05150 1740721e2cb82ff7a2ffba82a47ec590 400 SMART SM00191 29 88 3.8 T 23-04-2016 IPR013519 Integrin alpha beta-propellor Reactome: REACT_13552 DC74_RS05150 1740721e2cb82ff7a2ffba82a47ec590 400 SUPERFAMILY SSF69318 139 377 1.31E-43 T 23-04-2016 DC74_RS05150 1740721e2cb82ff7a2ffba82a47ec590 400 SUPERFAMILY SSF69318 19 126 2.88E-14 T 23-04-2016 DC74_RS05150 1740721e2cb82ff7a2ffba82a47ec590 400 Gene3D G3DSA:2.130.10.130 16 233 1.2E-23 T 23-04-2016 DC74_RS05150 1740721e2cb82ff7a2ffba82a47ec590 400 Gene3D G3DSA:2.130.10.130 252 381 1.0E-18 T 23-04-2016 DC74_RS05150 1740721e2cb82ff7a2ffba82a47ec590 400 PANTHER PTHR23304:SF93 21 375 1.2E-30 T 23-04-2016 DC74_RS05150 1740721e2cb82ff7a2ffba82a47ec590 400 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 41 104 1.6E-10 T 23-04-2016 DC74_RS05150 1740721e2cb82ff7a2ffba82a47ec590 400 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 173 219 6.6E-10 T 23-04-2016 DC74_RS05150 1740721e2cb82ff7a2ffba82a47ec590 400 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 309 370 1.2E-12 T 23-04-2016 DC74_RS05150 1740721e2cb82ff7a2ffba82a47ec590 400 PANTHER PTHR23304 21 375 1.2E-30 T 23-04-2016 DC74_RS29735 f66cd55a3265df55ff1a716239f06277 347 Gene3D G3DSA:3.40.50.2300 137 320 1.2E-40 T 23-04-2016 DC74_RS29735 f66cd55a3265df55ff1a716239f06277 347 Pfam PF13407 Periplasmic binding protein domain 27 283 2.2E-59 T 23-04-2016 IPR025997 Periplasmic binding protein DC74_RS29735 f66cd55a3265df55ff1a716239f06277 347 PANTHER PTHR30036 1 333 2.3E-109 T 23-04-2016 DC74_RS29735 f66cd55a3265df55ff1a716239f06277 347 Gene3D G3DSA:3.40.50.2300 22 136 9.8E-25 T 23-04-2016 DC74_RS29735 f66cd55a3265df55ff1a716239f06277 347 SUPERFAMILY SSF53822 21 320 9.26E-64 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS29735 f66cd55a3265df55ff1a716239f06277 347 PANTHER PTHR30036:SF1 1 333 2.3E-109 T 23-04-2016 DC74_RS21820 efb47c0e7c733cbb227ba20006e07ec0 440 PANTHER PTHR11271 24 430 3.1E-66 T 23-04-2016 DC74_RS21820 efb47c0e7c733cbb227ba20006e07ec0 440 SUPERFAMILY SSF51556 66 354 3.57E-58 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS21820 efb47c0e7c733cbb227ba20006e07ec0 440 Gene3D G3DSA:3.20.20.140 72 370 1.0E-54 T 23-04-2016 DC74_RS21820 efb47c0e7c733cbb227ba20006e07ec0 440 SUPERFAMILY SSF51338 19 66 1.62E-17 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS21820 efb47c0e7c733cbb227ba20006e07ec0 440 SUPERFAMILY SSF51338 354 428 1.62E-17 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS21820 efb47c0e7c733cbb227ba20006e07ec0 440 Pfam PF01979 Amidohydrolase family 64 401 1.7E-37 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS21820 efb47c0e7c733cbb227ba20006e07ec0 440 Gene3D G3DSA:2.30.40.10 21 71 6.0E-9 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS21820 efb47c0e7c733cbb227ba20006e07ec0 440 PANTHER PTHR11271:SF7 24 430 3.1E-66 T 23-04-2016 DC74_RS28565 f775c903f388f72a4de3ee4dd3a23322 476 PIRSF PIRSF017804 1 475 1.0E-106 T 23-04-2016 IPR006707 Type VII secretion system membrane protein EccD DC74_RS28565 f775c903f388f72a4de3ee4dd3a23322 476 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 1 472 7.1E-54 T 23-04-2016 IPR006707 Type VII secretion system membrane protein EccD DC74_RS28565 f775c903f388f72a4de3ee4dd3a23322 476 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 1 72 2.4E-16 T 23-04-2016 IPR024962 YukD-like DC74_RS21630 8f12473d56f1d11f62f73c2f5293d9da 295 PANTHER PTHR30419:SF6 1 288 9.6E-138 T 23-04-2016 DC74_RS21630 8f12473d56f1d11f62f73c2f5293d9da 295 SUPERFAMILY SSF46785 1 84 8.07E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21630 8f12473d56f1d11f62f73c2f5293d9da 295 SUPERFAMILY SSF53850 88 287 3.44E-31 T 23-04-2016 DC74_RS21630 8f12473d56f1d11f62f73c2f5293d9da 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS21630 8f12473d56f1d11f62f73c2f5293d9da 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS21630 8f12473d56f1d11f62f73c2f5293d9da 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-10 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS21630 8f12473d56f1d11f62f73c2f5293d9da 295 PANTHER PTHR30419 1 288 9.6E-138 T 23-04-2016 DC74_RS21630 8f12473d56f1d11f62f73c2f5293d9da 295 Gene3D G3DSA:1.10.10.10 1 80 5.7E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS21630 8f12473d56f1d11f62f73c2f5293d9da 295 Gene3D G3DSA:3.40.190.10 90 175 3.5E-11 T 23-04-2016 DC74_RS21630 8f12473d56f1d11f62f73c2f5293d9da 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.7E-20 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS21630 8f12473d56f1d11f62f73c2f5293d9da 295 Gene3D G3DSA:3.40.190.10 176 252 9.4E-20 T 23-04-2016 DC74_RS21630 8f12473d56f1d11f62f73c2f5293d9da 295 Pfam PF03466 LysR substrate binding domain 87 286 7.5E-34 T 23-04-2016 IPR005119 LysR, substrate-binding DC74_RS23805 1fadd2edfaaa49af19e9941e6b20e8eb 351 SUPERFAMILY SSF75011 53 285 1.16E-18 T 23-04-2016 DC74_RS23805 1fadd2edfaaa49af19e9941e6b20e8eb 351 Gene3D G3DSA:2.130.10.10 55 276 3.4E-13 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS24790 3c5572d44b03de20d82ca68708b287c1 158 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 42 141 2.8E-16 T 23-04-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 UniPathway: UPA00223 DC74_RS24790 3c5572d44b03de20d82ca68708b287c1 158 Gene3D G3DSA:1.20.950.10 30 157 6.0E-39 T 23-04-2016 DC74_RS24790 3c5572d44b03de20d82ca68708b287c1 158 SUPERFAMILY SSF81343 33 155 1.18E-32 T 23-04-2016 DC74_RS03790 34173177ffd23f6f110cc85f69c6bea8 284 Pfam PF14247 Putative metallopeptidase 63 276 1.6E-54 T 23-04-2016 IPR025644 Putative metallopeptidase DC74_RS13275 ce5774b195fd1bd024a6d001ae09e496 512 Pfam PF13520 Amino acid permease 34 441 4.3E-26 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS13275 ce5774b195fd1bd024a6d001ae09e496 512 PIRSF PIRSF006060 11 494 3.3E-53 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS13275 ce5774b195fd1bd024a6d001ae09e496 512 PANTHER PTHR11785 25 482 2.0E-24 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS16080 d403e6ddece9a4253abfe413f38f4130 300 PANTHER PTHR40267 8 250 3.5E-75 T 23-04-2016 DC74_RS16080 d403e6ddece9a4253abfe413f38f4130 300 Pfam PF01177 Asp/Glu/Hydantoin racemase 63 225 1.0E-8 T 23-04-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS12195 b5e9475f607a63208c0181716ca75561 158 SUPERFAMILY SSF102405 2 154 2.2E-11 T 23-04-2016 DC74_RS12195 b5e9475f607a63208c0181716ca75561 158 Gene3D G3DSA:3.40.50.450 37 153 1.1E-5 T 23-04-2016 DC74_RS22390 9dbd9edcc77162209f90c2cbf92e5451 232 PANTHER PTHR30086 2 226 6.8E-74 T 23-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 DC74_RS22390 9dbd9edcc77162209f90c2cbf92e5451 232 PIRSF PIRSF006324 1 231 1.6E-49 T 23-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 DC74_RS22390 9dbd9edcc77162209f90c2cbf92e5451 232 Pfam PF01810 LysE type translocator 17 228 4.1E-43 T 23-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 DC74_RS22390 9dbd9edcc77162209f90c2cbf92e5451 232 PANTHER PTHR30086:SF15 2 226 6.8E-74 T 23-04-2016 DC74_RS00130 1f9330f9726bce9968cc91e9fa821d17 279 PANTHER PTHR30007:SF0 8 276 1.2E-116 T 23-04-2016 DC74_RS00130 1f9330f9726bce9968cc91e9fa821d17 279 PANTHER PTHR30007 8 276 1.2E-116 T 23-04-2016 DC74_RS00130 1f9330f9726bce9968cc91e9fa821d17 279 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 90 1.4E-24 T 23-04-2016 IPR025161 Putative transposase IS4/IS5 family DC74_RS00130 1f9330f9726bce9968cc91e9fa821d17 279 Pfam PF13586 Transposase DDE domain 193 260 1.8E-12 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS26435 d4220ab2133950e6c245c6e4d0465e29 409 Pfam PF01547 Bacterial extracellular solute-binding protein 34 321 4.3E-38 T 23-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 DC74_RS26435 d4220ab2133950e6c245c6e4d0465e29 409 PANTHER PTHR30061:SF24 1 409 3.0E-79 T 23-04-2016 DC74_RS26435 d4220ab2133950e6c245c6e4d0465e29 409 Gene3D G3DSA:3.40.190.10 24 149 9.0E-26 T 23-04-2016 DC74_RS26435 d4220ab2133950e6c245c6e4d0465e29 409 Gene3D G3DSA:3.40.190.10 150 334 8.6E-32 T 23-04-2016 DC74_RS26435 d4220ab2133950e6c245c6e4d0465e29 409 SUPERFAMILY SSF53850 6 407 1.54E-66 T 23-04-2016 DC74_RS26435 d4220ab2133950e6c245c6e4d0465e29 409 PANTHER PTHR30061 1 409 3.0E-79 T 23-04-2016 DC74_RS25355 851833e4614df7326784f323a0638e71 429 PANTHER PTHR28004:SF1 21 423 1.1E-166 T 23-04-2016 DC74_RS25355 851833e4614df7326784f323a0638e71 429 Gene3D G3DSA:3.20.20.10 145 269 2.7E-11 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS25355 851833e4614df7326784f323a0638e71 429 Pfam PF01168 Alanine racemase, N-terminal domain 58 264 9.3E-12 T 23-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS25355 851833e4614df7326784f323a0638e71 429 SUPERFAMILY SSF51419 59 276 1.15E-24 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS25355 851833e4614df7326784f323a0638e71 429 SMART SM01119 318 416 5.6E-36 T 23-04-2016 IPR026956 D-serine dehydratase-like domain DC74_RS25355 851833e4614df7326784f323a0638e71 429 Pfam PF14031 Putative serine dehydratase domain 318 413 3.8E-16 T 23-04-2016 IPR026956 D-serine dehydratase-like domain DC74_RS25355 851833e4614df7326784f323a0638e71 429 PANTHER PTHR28004 21 423 1.1E-166 T 23-04-2016 DC74_RS14995 e7e50818d598c42e2a650bc131db26ca 264 PANTHER PTHR31284 74 264 9.2E-46 T 23-04-2016 DC74_RS14995 e7e50818d598c42e2a650bc131db26ca 264 SUPERFAMILY SSF56784 97 261 5.0E-17 T 23-04-2016 IPR023214 HAD-like domain DC74_RS14995 e7e50818d598c42e2a650bc131db26ca 264 PANTHER PTHR31284:SF10 74 264 9.2E-46 T 23-04-2016 DC74_RS14995 e7e50818d598c42e2a650bc131db26ca 264 Gene3D G3DSA:3.40.50.1000 96 247 9.0E-16 T 23-04-2016 IPR023214 HAD-like domain DC74_RS14995 e7e50818d598c42e2a650bc131db26ca 264 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 67 263 5.5E-33 T 23-04-2016 IPR005519 Acid phosphatase, class B-like DC74_RS21000 624ac8b05ecad9f288c517bdb18bb686 359 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 8 357 49.871 T 23-04-2016 IPR024892 Putative phenylalanine aminotransferase DC74_RS21000 624ac8b05ecad9f288c517bdb18bb686 359 Gene3D G3DSA:3.40.640.10 47 245 1.5E-46 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS21000 624ac8b05ecad9f288c517bdb18bb686 359 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 354 4.6E-89 T 23-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 DC74_RS21000 624ac8b05ecad9f288c517bdb18bb686 359 SUPERFAMILY SSF53383 25 351 3.16E-78 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS21000 624ac8b05ecad9f288c517bdb18bb686 359 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 356 50.792 T 23-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 DC74_RS21000 624ac8b05ecad9f288c517bdb18bb686 359 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 220 229 - T 23-04-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 DC74_RS21000 624ac8b05ecad9f288c517bdb18bb686 359 Gene3D G3DSA:3.90.1150.10 246 355 5.4E-32 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS21000 624ac8b05ecad9f288c517bdb18bb686 359 PANTHER PTHR11751 10 357 1.1E-102 T 23-04-2016 DC74_RS21000 624ac8b05ecad9f288c517bdb18bb686 359 Pfam PF00155 Aminotransferase class I and II 33 343 1.6E-52 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS21000 624ac8b05ecad9f288c517bdb18bb686 359 PANTHER PTHR11751:SF347 10 357 1.1E-102 T 23-04-2016 DC74_RS13915 801b264fc55aef09257024007417b1d0 390 PIRSF PIRSF015582 14 382 9.5E-79 T 23-04-2016 IPR011206 Citrate lyase beta subunit-like DC74_RS13915 801b264fc55aef09257024007417b1d0 390 Gene3D G3DSA:3.20.20.60 36 316 5.8E-41 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS13915 801b264fc55aef09257024007417b1d0 390 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 372 2.6E-128 T 23-04-2016 DC74_RS13915 801b264fc55aef09257024007417b1d0 390 SUPERFAMILY SSF51621 35 253 4.6E-26 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS13915 801b264fc55aef09257024007417b1d0 390 SUPERFAMILY SSF51621 283 316 4.6E-26 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS36740 e74dd4da6c10345a316a5b243d56a136 401 PANTHER PTHR39192 95 398 2.4E-30 T 23-04-2016 DC74_RS36740 e74dd4da6c10345a316a5b243d56a136 401 Pfam PF09375 Imelysin 162 388 2.3E-19 T 23-04-2016 DC74_RS05720 90ea24dc4a3e6f9dc79a44e9d78a5ee6 253 SUPERFAMILY SSF53474 8 225 3.54E-39 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05720 90ea24dc4a3e6f9dc79a44e9d78a5ee6 253 Gene3D G3DSA:3.40.50.1820 5 224 6.2E-34 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05720 90ea24dc4a3e6f9dc79a44e9d78a5ee6 253 SMART SM00824 Thioesterase 15 237 4.7E-4 T 23-04-2016 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 DC74_RS05720 90ea24dc4a3e6f9dc79a44e9d78a5ee6 253 Pfam PF00975 Thioesterase domain 13 226 4.9E-35 T 23-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 DC74_RS05720 90ea24dc4a3e6f9dc79a44e9d78a5ee6 253 PANTHER PTHR11487 13 251 9.1E-54 T 23-04-2016 IPR012223 Thioesterase type II, NRPS/PKS/S-FAS GO:0009058 DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 PANTHER PTHR11451:SF5 8 404 3.7E-146 T 23-04-2016 DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 Gene3D G3DSA:3.40.50.800 300 402 1.2E-15 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 7 397 1.8E-126 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 Gene3D G3DSA:3.30.930.10 8 298 1.7E-90 T 23-04-2016 DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 90 297 5.4E-28 T 23-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 PANTHER PTHR11451 8 404 3.7E-146 T 23-04-2016 DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 SUPERFAMILY SSF52954 298 409 5.29E-18 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 Pfam PF03129 Anticodon binding domain 310 396 7.8E-7 T 23-04-2016 IPR004154 Anticodon-binding DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 SUPERFAMILY SSF55681 8 295 4.18E-82 T 23-04-2016 DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 PRINTS PR01047 Threonyl-tRNA synthetase signature 129 152 2.3E-44 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 PRINTS PR01047 Threonyl-tRNA synthetase signature 96 124 2.3E-44 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 PRINTS PR01047 Threonyl-tRNA synthetase signature 303 315 2.3E-44 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 PRINTS PR01047 Threonyl-tRNA synthetase signature 276 289 2.3E-44 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS23060 388591c3b061615aab63d805435fa3d2 411 PRINTS PR01047 Threonyl-tRNA synthetase signature 233 261 2.3E-44 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DC74_RS02645 79f866b2e6a993f1fb498a5a72d5773c 374 Pfam PF13579 Glycosyl transferase 4-like domain 24 179 5.6E-12 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain DC74_RS02645 79f866b2e6a993f1fb498a5a72d5773c 374 Pfam PF00534 Glycosyl transferases group 1 191 347 2.8E-23 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 DC74_RS02645 79f866b2e6a993f1fb498a5a72d5773c 374 SUPERFAMILY SSF53756 5 367 1.85E-54 T 23-04-2016 DC74_RS02645 79f866b2e6a993f1fb498a5a72d5773c 374 Gene3D G3DSA:3.40.50.2000 187 347 6.3E-19 T 23-04-2016 DC74_RS02645 79f866b2e6a993f1fb498a5a72d5773c 374 PANTHER PTHR12526 1 367 1.4E-37 T 23-04-2016 DC74_RS12710 bea359551a4ea323f17f861f76bc0909 102 PANTHER PTHR37424 2 83 2.2E-19 T 23-04-2016 DC74_RS12710 bea359551a4ea323f17f861f76bc0909 102 PANTHER PTHR37424:SF1 2 83 2.2E-19 T 23-04-2016 DC74_RS12710 bea359551a4ea323f17f861f76bc0909 102 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 1.4E-11 T 23-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain DC74_RS20880 5b79efdbd716dfed39ffd744a1cf4ae4 230 Gene3D G3DSA:1.25.40.10 11 111 1.7E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS32755 956bdd2192257f3b438dacbb172bdb73 277 PANTHER PTHR11358 36 251 2.4E-35 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS32755 956bdd2192257f3b438dacbb172bdb73 277 SUPERFAMILY SSF52768 38 251 9.0E-44 T 23-04-2016 DC74_RS32755 956bdd2192257f3b438dacbb172bdb73 277 PRINTS PR00116 Arginase signature 77 92 5.4E-12 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS32755 956bdd2192257f3b438dacbb172bdb73 277 PRINTS PR00116 Arginase signature 197 226 5.4E-12 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS32755 956bdd2192257f3b438dacbb172bdb73 277 PRINTS PR00116 Arginase signature 101 128 5.4E-12 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS32755 956bdd2192257f3b438dacbb172bdb73 277 Gene3D G3DSA:3.40.800.10 37 252 2.5E-42 T 23-04-2016 IPR023696 Ureohydrolase domain DC74_RS32755 956bdd2192257f3b438dacbb172bdb73 277 Pfam PF00491 Arginase family 61 252 8.8E-30 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 DC74_RS10655 0bf59cdc5967b214d42112678dac045b 346 SUPERFAMILY SSF46785 23 122 3.75E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10655 0bf59cdc5967b214d42112678dac045b 346 SUPERFAMILY SSF53850 127 302 8.83E-5 T 23-04-2016 DC74_RS10655 0bf59cdc5967b214d42112678dac045b 346 Gene3D G3DSA:1.10.10.10 23 111 6.4E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10655 0bf59cdc5967b214d42112678dac045b 346 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 89 2.2E-8 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DC74_RS24840 bd49101bbfb0c5744d12ed2e2a54ed5c 171 Gene3D G3DSA:3.40.50.300 5 165 1.8E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24840 bd49101bbfb0c5744d12ed2e2a54ed5c 171 Pfam PF01202 Shikimate kinase 14 164 9.7E-9 T 23-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 DC74_RS24840 bd49101bbfb0c5744d12ed2e2a54ed5c 171 SUPERFAMILY SSF52540 4 167 2.43E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24840 bd49101bbfb0c5744d12ed2e2a54ed5c 171 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 7 162 2.0E-56 T 23-04-2016 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530|UniPathway: UPA00792 DC74_RS24840 bd49101bbfb0c5744d12ed2e2a54ed5c 171 PANTHER PTHR11603 6 168 1.5E-79 T 23-04-2016 DC74_RS22875 bb3e4cee5867632f21a2a564b858c3eb 483 SUPERFAMILY SSF52540 40 433 2.86E-33 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22875 bb3e4cee5867632f21a2a564b858c3eb 483 Pfam PF12846 AAA-like domain 69 358 1.7E-11 T 23-04-2016 DC74_RS22875 bb3e4cee5867632f21a2a564b858c3eb 483 Gene3D G3DSA:3.40.50.300 254 384 2.2E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22875 bb3e4cee5867632f21a2a564b858c3eb 483 Gene3D G3DSA:3.40.50.300 73 155 2.2E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25275 052dc2339eeb4009b8df0600c9f14f55 135 Gene3D G3DSA:3.40.50.1010 7 129 1.5E-6 T 23-04-2016 IPR029060 PIN domain-like DC74_RS25275 052dc2339eeb4009b8df0600c9f14f55 135 SUPERFAMILY SSF88723 8 131 9.16E-13 T 23-04-2016 IPR029060 PIN domain-like DC74_RS25275 052dc2339eeb4009b8df0600c9f14f55 135 Pfam PF01850 PIN domain 10 120 7.5E-8 T 23-04-2016 IPR002716 PIN domain DC74_RS16705 8cd9640435e8795067aa12b012cb7095 434 PANTHER PTHR24362:SF160 187 357 1.5E-65 T 23-04-2016 DC74_RS16705 8cd9640435e8795067aa12b012cb7095 434 PANTHER PTHR24362 8 168 1.5E-65 T 23-04-2016 DC74_RS16705 8cd9640435e8795067aa12b012cb7095 434 PANTHER PTHR24362 187 357 1.5E-65 T 23-04-2016 DC74_RS16705 8cd9640435e8795067aa12b012cb7095 434 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 126 138 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DC74_RS16705 8cd9640435e8795067aa12b012cb7095 434 Gene3D G3DSA:3.30.200.20 4 72 1.2E-15 T 23-04-2016 DC74_RS16705 8cd9640435e8795067aa12b012cb7095 434 SUPERFAMILY SSF56112 5 277 1.37E-62 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS16705 8cd9640435e8795067aa12b012cb7095 434 Gene3D G3DSA:1.10.510.10 73 276 4.8E-44 T 23-04-2016 DC74_RS16705 8cd9640435e8795067aa12b012cb7095 434 SMART SM00220 9 283 1.9E-59 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS16705 8cd9640435e8795067aa12b012cb7095 434 Pfam PF00069 Protein kinase domain 9 275 9.2E-44 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DC74_RS16705 8cd9640435e8795067aa12b012cb7095 434 PANTHER PTHR24362:SF160 8 168 1.5E-65 T 23-04-2016 DC74_RS38210 17babfe8efa79feee6e6b149532a56ad 285 Pfam PF09900 Predicted membrane protein (DUF2127) 104 248 5.4E-25 T 23-04-2016 IPR021125 Protein of unknown function DUF2127 DC74_RS08820 4d4f9eb2920ead2f444938472b87c10e 174 PANTHER PTHR41289 4 164 1.9E-29 T 23-04-2016 DC74_RS08820 4d4f9eb2920ead2f444938472b87c10e 174 Pfam PF08877 MepB protein 35 156 2.1E-47 T 23-04-2016 IPR011235 MepB-like DC74_RS34890 8accde207adf937afaf4501dbef205d6 386 SUPERFAMILY SSF56601 40 298 1.36E-41 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS34890 8accde207adf937afaf4501dbef205d6 386 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 47 277 2.3E-30 T 23-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 DC74_RS34890 8accde207adf937afaf4501dbef205d6 386 Gene3D G3DSA:3.40.710.10 44 299 1.7E-58 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS34890 8accde207adf937afaf4501dbef205d6 386 PANTHER PTHR21581:SF1 45 298 4.4E-56 T 23-04-2016 DC74_RS34890 8accde207adf937afaf4501dbef205d6 386 PANTHER PTHR21581 45 298 4.4E-56 T 23-04-2016 DC74_RS25980 fb132ab652c35de7584a4e2e887cb5d3 315 Pfam PF13490 Putative zinc-finger 16 44 7.9E-7 T 23-04-2016 IPR027383 Putative zinc-finger DC74_RS31275 4673b4329b39419c7fdef3ca8235fda1 404 PANTHER PTHR21021 247 394 3.7E-32 T 23-04-2016 DC74_RS31275 4673b4329b39419c7fdef3ca8235fda1 404 PANTHER PTHR21021 108 218 3.7E-32 T 23-04-2016 DC74_RS31275 4673b4329b39419c7fdef3ca8235fda1 404 SMART SM00331 142 385 7.7E-38 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS31275 4673b4329b39419c7fdef3ca8235fda1 404 SUPERFAMILY SSF81606 244 384 3.4E-9 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS31275 4673b4329b39419c7fdef3ca8235fda1 404 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 171 385 2.7E-37 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS38995 79fadf35e70f51be43a1066fc282a376 221 PANTHER PTHR36529 1 211 5.0E-45 T 23-04-2016 DC74_RS38995 79fadf35e70f51be43a1066fc282a376 221 SUPERFAMILY SSF53448 17 199 1.18E-26 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS38995 79fadf35e70f51be43a1066fc282a376 221 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 53 163 7.1E-20 T 23-04-2016 IPR018641 Transferase 1, rSAM/selenodomain-associated DC74_RS38995 79fadf35e70f51be43a1066fc282a376 221 Gene3D G3DSA:3.90.550.10 15 174 3.3E-23 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS37630 dc3653a3efea30ff937111179d894a20 152 PANTHER PTHR33221:SF1 2 139 1.7E-37 T 23-04-2016 DC74_RS37630 dc3653a3efea30ff937111179d894a20 152 Pfam PF02082 Transcriptional regulator 1 83 7.1E-26 T 23-04-2016 IPR000944 Transcription regulator Rrf2-type DC74_RS37630 dc3653a3efea30ff937111179d894a20 152 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 1.4E-32 T 23-04-2016 IPR000944 Transcription regulator Rrf2-type DC74_RS37630 dc3653a3efea30ff937111179d894a20 152 SUPERFAMILY SSF46785 2 132 3.63E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37630 dc3653a3efea30ff937111179d894a20 152 Gene3D G3DSA:1.10.10.10 1 132 9.5E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37630 dc3653a3efea30ff937111179d894a20 152 PANTHER PTHR33221 2 139 1.7E-37 T 23-04-2016 DC74_RS40535 e3340ad0a5cff01038b5fb3793c0b007 519 SUPERFAMILY SSF140453 64 127 3.66E-5 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS29380 87c6dda1a5726b007fb58d95b3225a06 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 7.0E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS29380 87c6dda1a5726b007fb58d95b3225a06 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 7.0E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS29380 87c6dda1a5726b007fb58d95b3225a06 216 PANTHER PTHR30328:SF29 1 126 1.6E-18 T 23-04-2016 DC74_RS29380 87c6dda1a5726b007fb58d95b3225a06 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.1E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS29380 87c6dda1a5726b007fb58d95b3225a06 216 PANTHER PTHR30328 1 126 1.6E-18 T 23-04-2016 DC74_RS29380 87c6dda1a5726b007fb58d95b3225a06 216 SUPERFAMILY SSF46689 3 79 2.1E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS29380 87c6dda1a5726b007fb58d95b3225a06 216 Gene3D G3DSA:1.10.357.10 2 196 8.8E-28 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS27290 a80895bc668d9ec8a2be47c8fb9234bd 262 PANTHER PTHR24220 22 260 4.3E-154 T 23-04-2016 DC74_RS27290 a80895bc668d9ec8a2be47c8fb9234bd 262 SMART SM00382 49 235 8.6E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS27290 a80895bc668d9ec8a2be47c8fb9234bd 262 Pfam PF00005 ABC transporter 40 186 2.4E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS27290 a80895bc668d9ec8a2be47c8fb9234bd 262 PANTHER PTHR24220:SF484 22 260 4.3E-154 T 23-04-2016 DC74_RS27290 a80895bc668d9ec8a2be47c8fb9234bd 262 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS27290 a80895bc668d9ec8a2be47c8fb9234bd 262 SUPERFAMILY SSF52540 23 239 7.14E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27290 a80895bc668d9ec8a2be47c8fb9234bd 262 Gene3D G3DSA:3.40.50.300 23 239 5.0E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05215 335c846c6dc55d996e37d9be7114ba6d 69 PANTHER PTHR35530 2 69 1.3E-34 T 23-04-2016 DC74_RS05215 335c846c6dc55d996e37d9be7114ba6d 69 PANTHER PTHR35530:SF2 2 69 1.3E-34 T 23-04-2016 DC74_RS05215 335c846c6dc55d996e37d9be7114ba6d 69 SUPERFAMILY SSF55331 2 62 5.7E-12 T 23-04-2016 IPR014347 Tautomerase/MIF superfamily DC74_RS05215 335c846c6dc55d996e37d9be7114ba6d 69 Gene3D G3DSA:3.30.429.20 1 60 1.6E-15 T 23-04-2016 DC74_RS05215 335c846c6dc55d996e37d9be7114ba6d 69 Pfam PF01361 Tautomerase enzyme 2 62 1.8E-20 T 23-04-2016 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 DC74_RS03470 db9ea865f82b63af3f3ee6f517a686e9 105 Gene3D G3DSA:3.30.870.10 16 78 2.4E-6 T 23-04-2016 DC74_RS03470 db9ea865f82b63af3f3ee6f517a686e9 105 SUPERFAMILY SSF56024 14 79 2.64E-5 T 23-04-2016 DC74_RS14400 e6de3b5ccbfa0b347dd7a7a554e23b9b 194 Gene3D G3DSA:2.40.320.10 3 162 5.2E-10 T 23-04-2016 IPR023577 CYTH domain DC74_RS14400 e6de3b5ccbfa0b347dd7a7a554e23b9b 194 SUPERFAMILY SSF55154 3 162 1.96E-10 T 23-04-2016 IPR033469 CYTH-like domain DC74_RS04395 259e257226b9c0a113f48677bd7d3468 241 Pfam PF14451 Mut7-C ubiquitin 4 82 4.7E-21 T 23-04-2016 IPR027798 Ubiquitin Mut7-C domain DC74_RS04395 259e257226b9c0a113f48677bd7d3468 241 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 179 200 - T 23-04-2016 IPR007087 Zinc finger, C2H2 GO:0046872 DC74_RS04395 259e257226b9c0a113f48677bd7d3468 241 PANTHER PTHR39081 75 236 8.9E-14 T 23-04-2016 DC74_RS04395 259e257226b9c0a113f48677bd7d3468 241 Pfam PF01927 Mut7-C RNAse domain 90 231 4.2E-42 T 23-04-2016 IPR002782 Mut7-C RNAse domain DC74_RS02375 bf0f703c7446ca86fb8b6106420a32ea 334 Pfam PF06675 Protein of unknown function (DUF1177) 57 325 3.8E-132 T 23-04-2016 IPR009561 Protein of unknown function DUF1177 DC74_RS38525 af3a9632c457d562fae50ae1b4dec020 246 Gene3D G3DSA:3.30.530.20 3 138 5.1E-24 T 23-04-2016 IPR023393 START-like domain DC74_RS38525 af3a9632c457d562fae50ae1b4dec020 246 SUPERFAMILY SSF55961 3 135 3.44E-23 T 23-04-2016 DC74_RS38525 af3a9632c457d562fae50ae1b4dec020 246 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 133 6.6E-10 T 23-04-2016 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 DC74_RS23855 316b8934f8ce98ae17208c1e45283568 267 Gene3D G3DSA:1.20.120.450 5 140 9.0E-9 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS23855 316b8934f8ce98ae17208c1e45283568 267 SUPERFAMILY SSF109854 7 155 4.43E-37 T 23-04-2016 DC74_RS23855 316b8934f8ce98ae17208c1e45283568 267 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 14 150 1.2E-30 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS23855 316b8934f8ce98ae17208c1e45283568 267 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 9 260 1.8E-107 T 23-04-2016 IPR017518 Conserved hypothetical protein CHP03084 DC74_RS23855 316b8934f8ce98ae17208c1e45283568 267 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 13 227 4.9E-52 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS20730 721e9147d6a7a30ae1beb89437e9f0c0 318 Gene3D G3DSA:3.90.1530.10 36 136 6.7E-40 T 23-04-2016 DC74_RS20730 721e9147d6a7a30ae1beb89437e9f0c0 318 Pfam PF02195 ParB-like nuclease domain 41 129 2.2E-28 T 23-04-2016 IPR003115 ParB/Sulfiredoxin DC74_RS20730 721e9147d6a7a30ae1beb89437e9f0c0 318 SMART SM00470 40 130 5.8E-38 T 23-04-2016 IPR003115 ParB/Sulfiredoxin DC74_RS20730 721e9147d6a7a30ae1beb89437e9f0c0 318 PANTHER PTHR33375:SF1 37 306 4.8E-103 T 23-04-2016 DC74_RS20730 721e9147d6a7a30ae1beb89437e9f0c0 318 SUPERFAMILY SSF109709 122 231 2.62E-33 T 23-04-2016 DC74_RS20730 721e9147d6a7a30ae1beb89437e9f0c0 318 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 38 215 5.2E-63 T 23-04-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 DC74_RS20730 721e9147d6a7a30ae1beb89437e9f0c0 318 SUPERFAMILY SSF110849 31 133 2.35E-29 T 23-04-2016 IPR003115 ParB/Sulfiredoxin DC74_RS20730 721e9147d6a7a30ae1beb89437e9f0c0 318 PANTHER PTHR33375 37 306 4.8E-103 T 23-04-2016 DC74_RS32435 be7de4e1a239d4768ca2c23a73a064eb 596 Pfam PF16861 Carbamoyltransferase C-terminus 424 595 2.2E-70 T 23-04-2016 IPR031730 Carbamoyltransferase, C-terminal DC74_RS32435 be7de4e1a239d4768ca2c23a73a064eb 596 Pfam PF02543 Carbamoyltransferase N-terminus 34 371 2.4E-39 T 23-04-2016 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 DC74_RS32435 be7de4e1a239d4768ca2c23a73a064eb 596 PANTHER PTHR34847 25 596 2.7E-107 T 23-04-2016 DC74_RS32435 be7de4e1a239d4768ca2c23a73a064eb 596 SUPERFAMILY SSF53067 155 242 4.01E-6 T 23-04-2016 DC74_RS32435 be7de4e1a239d4768ca2c23a73a064eb 596 SUPERFAMILY SSF53067 280 376 4.01E-6 T 23-04-2016 DC74_RS32435 be7de4e1a239d4768ca2c23a73a064eb 596 SUPERFAMILY SSF53067 37 103 4.01E-6 T 23-04-2016 DC74_RS14650 b92de5d69a40bdcf62420113d4325cd1 98 PANTHER PTHR23419 1 97 1.7E-32 T 23-04-2016 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 DC74_RS14650 b92de5d69a40bdcf62420113d4325cd1 98 Pfam PF03091 CutA1 divalent ion tolerance protein 1 95 3.9E-32 T 23-04-2016 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 DC74_RS14650 b92de5d69a40bdcf62420113d4325cd1 98 Gene3D G3DSA:3.30.70.830 1 97 2.0E-35 T 23-04-2016 DC74_RS14650 b92de5d69a40bdcf62420113d4325cd1 98 SUPERFAMILY SSF54913 1 97 5.19E-32 T 23-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta DC74_RS18115 6ed11d460c4d2add5f0b0e570beb1889 69 Pfam PF04149 Domain of unknown function (DUF397) 10 61 5.5E-20 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS23265 c41958c9dac0d89bc75a8e52775e8f50 269 Gene3D G3DSA:3.40.50.150 43 179 6.7E-4 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS23265 c41958c9dac0d89bc75a8e52775e8f50 269 SUPERFAMILY SSF53335 17 177 3.62E-11 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS33055 b0a6e3e5aac2613fd538a0ded98c11e9 222 Gene3D G3DSA:1.10.357.10 19 220 2.5E-27 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS33055 b0a6e3e5aac2613fd538a0ded98c11e9 222 PANTHER PTHR30055:SF54 13 216 3.1E-38 T 23-04-2016 DC74_RS33055 b0a6e3e5aac2613fd538a0ded98c11e9 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 3.1E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS33055 b0a6e3e5aac2613fd538a0ded98c11e9 222 PANTHER PTHR30055 13 216 3.1E-38 T 23-04-2016 DC74_RS33055 b0a6e3e5aac2613fd538a0ded98c11e9 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 3.5E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS33055 b0a6e3e5aac2613fd538a0ded98c11e9 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 3.5E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS33055 b0a6e3e5aac2613fd538a0ded98c11e9 222 SUPERFAMILY SSF46689 19 97 5.64E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04845 9adb8961d9d93c8ebb59fe8385116979 365 SUPERFAMILY SSF51395 1 363 9.95E-107 T 23-04-2016 DC74_RS04845 9adb8961d9d93c8ebb59fe8385116979 365 PANTHER PTHR22893:SF14 1 362 1.3E-142 T 23-04-2016 DC74_RS04845 9adb8961d9d93c8ebb59fe8385116979 365 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 340 1.7E-77 T 23-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 DC74_RS04845 9adb8961d9d93c8ebb59fe8385116979 365 Gene3D G3DSA:3.20.20.70 4 361 2.2E-115 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS04845 9adb8961d9d93c8ebb59fe8385116979 365 PANTHER PTHR22893 1 362 1.3E-142 T 23-04-2016 DC74_RS28595 7d8172e2787faf61a29c729e2bc02a50 185 Pfam PF10756 Bacterial PH domain 90 152 1.2E-5 T 23-04-2016 IPR019692 Protein of unknown function DUF2581 DC74_RS08740 93afdf95fa6f9c2532daf452e6c2b049 296 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 21 182 2.0E-28 T 23-04-2016 IPR025847 MEDS domain DC74_RS10135 0f7b05d9201a0ed1d24dc04870ef8421 420 Gene3D G3DSA:3.20.20.10 131 295 1.6E-6 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS10135 0f7b05d9201a0ed1d24dc04870ef8421 420 SUPERFAMILY SSF51419 43 292 9.16E-18 T 23-04-2016 IPR029066 PLP-binding barrel DC74_RS10135 0f7b05d9201a0ed1d24dc04870ef8421 420 Pfam PF01168 Alanine racemase, N-terminal domain 42 293 2.8E-15 T 23-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 DC74_RS18620 0478ad6403b1f0167bc38c632efc622f 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 23-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18620 0478ad6403b1f0167bc38c632efc622f 37 SUPERFAMILY SSF57840 1 37 3.53E-16 T 23-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18620 0478ad6403b1f0167bc38c632efc622f 37 PANTHER PTHR18804 1 37 2.1E-16 T 23-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18620 0478ad6403b1f0167bc38c632efc622f 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 2.0E-9 T 23-04-2016 DC74_RS18620 0478ad6403b1f0167bc38c632efc622f 37 Pfam PF00444 Ribosomal protein L36 1 37 4.2E-18 T 23-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18620 0478ad6403b1f0167bc38c632efc622f 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 9.0E-22 T 23-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS18620 0478ad6403b1f0167bc38c632efc622f 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.021 T 23-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS06965 79fb09c3d12147c3de8a02ba929bbcbe 244 Pfam PF14333 Domain of unknown function (DUF4389) 28 98 1.1E-8 T 23-04-2016 IPR025498 Protein of unknown function DUF4389 DC74_RS32205 e4d19ba44de727d1153d0e2381b77dde 125 Gene3D G3DSA:3.10.450.50 2 117 2.4E-4 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS32205 e4d19ba44de727d1153d0e2381b77dde 125 SUPERFAMILY SSF54427 7 117 3.87E-17 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS24765 9a0a9b45cd4dfc4b6f6a3a4d7dfd833e 169 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 163 5.6E-59 T 23-04-2016 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger DC74_RS09985 d8b3c08f18d3ee2a467477361828ea01 407 SUPERFAMILY SSF51445 102 325 5.91E-23 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS09985 d8b3c08f18d3ee2a467477361828ea01 407 PANTHER PTHR30032 229 350 7.6E-77 T 23-04-2016 DC74_RS09985 d8b3c08f18d3ee2a467477361828ea01 407 PANTHER PTHR30032 35 207 7.6E-77 T 23-04-2016 DC74_RS09985 d8b3c08f18d3ee2a467477361828ea01 407 PANTHER PTHR30032:SF2 229 350 7.6E-77 T 23-04-2016 DC74_RS09985 d8b3c08f18d3ee2a467477361828ea01 407 PANTHER PTHR30032:SF2 35 207 7.6E-77 T 23-04-2016 DC74_RS09985 d8b3c08f18d3ee2a467477361828ea01 407 Pfam PF02638 Glycosyl hydrolase-like 10 36 349 4.7E-85 T 23-04-2016 IPR003790 Glycosyl hydrolase-like 10 DC74_RS02435 eee592baf64c96e6771426d9b31f9bdd 332 Pfam PF08338 Domain of unknown function (DUF1731) 261 303 7.6E-10 T 23-04-2016 IPR013549 Domain of unknown function DUF1731 DC74_RS02435 eee592baf64c96e6771426d9b31f9bdd 332 PANTHER PTHR11092:SF0 1 312 2.8E-64 T 23-04-2016 DC74_RS02435 eee592baf64c96e6771426d9b31f9bdd 332 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 302 6.3E-63 T 23-04-2016 IPR010099 Epimerase family protein SDR39U1 DC74_RS02435 eee592baf64c96e6771426d9b31f9bdd 332 SUPERFAMILY SSF51735 1 305 8.68E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS02435 eee592baf64c96e6771426d9b31f9bdd 332 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 221 3.4E-10 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS02435 eee592baf64c96e6771426d9b31f9bdd 332 PANTHER PTHR11092 1 312 2.8E-64 T 23-04-2016 IPR010099 Epimerase family protein SDR39U1 DC74_RS02435 eee592baf64c96e6771426d9b31f9bdd 332 Gene3D G3DSA:3.40.50.720 1 245 2.9E-19 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS13775 214a500a5712c6eaa9b85fb5fbab6ba6 106 SUPERFAMILY SSF54909 4 99 1.71E-24 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS13775 214a500a5712c6eaa9b85fb5fbab6ba6 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 76 2.3E-16 T 23-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain DC74_RS13775 214a500a5712c6eaa9b85fb5fbab6ba6 106 Gene3D G3DSA:3.30.70.900 3 103 1.9E-36 T 23-04-2016 DC74_RS13775 214a500a5712c6eaa9b85fb5fbab6ba6 106 PANTHER PTHR34474 4 103 3.2E-20 T 23-04-2016 DC74_RS02890 86bfe38381a0714c6c527f0c6590ed1b 358 SUPERFAMILY SSF48576 22 335 6.17E-57 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS02890 86bfe38381a0714c6c527f0c6590ed1b 358 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 95 109 - T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 DC74_RS02890 86bfe38381a0714c6c527f0c6590ed1b 358 PANTHER PTHR12001 49 358 1.6E-70 T 23-04-2016 IPR017446 Polyprenyl synthetase-related DC74_RS02890 86bfe38381a0714c6c527f0c6590ed1b 358 Gene3D G3DSA:1.10.600.10 38 347 5.2E-60 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS02890 86bfe38381a0714c6c527f0c6590ed1b 358 Pfam PF00348 Polyprenyl synthetase 51 291 2.2E-44 T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 DC74_RS02890 86bfe38381a0714c6c527f0c6590ed1b 358 PANTHER PTHR12001:SF45 49 358 1.6E-70 T 23-04-2016 DC74_RS14135 e37502bccc4433d41df20023e9cdd66e 444 Pfam PF13556 PucR C-terminal helix-turn-helix domain 378 436 2.7E-20 T 23-04-2016 IPR025736 PucR C-terminal helix-turn-helix domain DC74_RS14135 e37502bccc4433d41df20023e9cdd66e 444 PANTHER PTHR33744 333 439 2.3E-21 T 23-04-2016 DC74_RS14135 e37502bccc4433d41df20023e9cdd66e 444 PANTHER PTHR33744:SF3 333 439 2.3E-21 T 23-04-2016 DC74_RS12420 d89440cd3bb988995b5ea868729d9166 248 Pfam PF01061 ABC-2 type transporter 23 208 1.1E-9 T 23-04-2016 IPR013525 ABC-2 type transporter GO:0016020 DC74_RS06415 caeac72ba3d1770e38e5a4cd539ea100 620 Gene3D G3DSA:1.50.10.10 223 606 1.7E-86 T 23-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 DC74_RS06415 caeac72ba3d1770e38e5a4cd539ea100 620 PANTHER PTHR31616 1 611 6.1E-159 T 23-04-2016 DC74_RS06415 caeac72ba3d1770e38e5a4cd539ea100 620 Pfam PF00723 Glycosyl hydrolases family 15 231 546 1.1E-44 T 23-04-2016 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: REACT_474 DC74_RS06415 caeac72ba3d1770e38e5a4cd539ea100 620 PANTHER PTHR31616:SF0 1 611 6.1E-159 T 23-04-2016 DC74_RS06415 caeac72ba3d1770e38e5a4cd539ea100 620 SUPERFAMILY SSF48208 203 601 4.68E-90 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 DC74_RS16235 123e6f303ef1e018d0ae9261bacb4d87 506 PANTHER PTHR11819:SF138 3 471 9.0E-68 T 23-04-2016 DC74_RS16235 123e6f303ef1e018d0ae9261bacb4d87 506 Pfam PF00474 Sodium:solute symporter family 43 436 2.4E-14 T 23-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS16235 123e6f303ef1e018d0ae9261bacb4d87 506 PANTHER PTHR11819 3 471 9.0E-68 T 23-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 Gene3D G3DSA:3.90.640.10 184 279 5.6E-27 T 23-04-2016 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 PANTHER PTHR19375 10 218 3.2E-154 T 23-04-2016 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 PANTHER PTHR19375 248 345 3.2E-154 T 23-04-2016 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 SUPERFAMILY SSF53067 147 348 2.79E-43 T 23-04-2016 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 Pfam PF06723 MreB/Mbl protein 11 223 5.4E-97 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 Pfam PF06723 MreB/Mbl protein 248 354 5.0E-37 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 SUPERFAMILY SSF53067 10 145 8.06E-40 T 23-04-2016 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 Gene3D G3DSA:3.30.420.40 158 183 1.8E-33 T 23-04-2016 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 Gene3D G3DSA:3.30.420.40 283 337 1.8E-33 T 23-04-2016 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 Gene3D G3DSA:3.30.420.40 10 157 6.3E-46 T 23-04-2016 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 PANTHER PTHR19375:SF117 10 218 3.2E-154 T 23-04-2016 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 PANTHER PTHR19375:SF117 248 345 3.2E-154 T 23-04-2016 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 46 64 3.8E-39 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 184 204 3.8E-39 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 66 89 3.8E-39 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS15655 c6a810ecf2640c05f3176aa605e4ae77 374 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 129 148 3.8E-39 T 23-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 DC74_RS07365 36ed58398c8157b4a2b31a283a7b7d95 112 Gene3D G3DSA:3.40.30.10 29 101 8.7E-4 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS28305 7987383000581597c275141e0e49a553 205 Pfam PF08719 Domain of unknown function (DUF1768) 55 199 3.7E-51 T 23-04-2016 IPR012816 Conserved hypothetical protein CHP02464 DC74_RS28305 7987383000581597c275141e0e49a553 205 PANTHER PTHR11079 108 189 5.9E-29 T 23-04-2016 DC74_RS28305 7987383000581597c275141e0e49a553 205 PANTHER PTHR11079:SF69 108 189 5.9E-29 T 23-04-2016 DC74_RS28305 7987383000581597c275141e0e49a553 205 SUPERFAMILY SSF143990 33 201 6.54E-51 T 23-04-2016 DC74_RS28305 7987383000581597c275141e0e49a553 205 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 40 199 1.5E-50 T 23-04-2016 IPR012816 Conserved hypothetical protein CHP02464 DC74_RS09140 182a05feefc5d820b9e65018bed40d4b 612 Pfam PF02543 Carbamoyltransferase N-terminus 6 346 2.1E-86 T 23-04-2016 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 DC74_RS09140 182a05feefc5d820b9e65018bed40d4b 612 PANTHER PTHR34847 3 488 1.7E-126 T 23-04-2016 DC74_RS09140 182a05feefc5d820b9e65018bed40d4b 612 PANTHER PTHR34847 510 608 1.7E-126 T 23-04-2016 DC74_RS09140 182a05feefc5d820b9e65018bed40d4b 612 SUPERFAMILY SSF53067 129 214 7.45E-19 T 23-04-2016 DC74_RS09140 182a05feefc5d820b9e65018bed40d4b 612 SUPERFAMILY SSF53067 2 82 7.45E-19 T 23-04-2016 DC74_RS09140 182a05feefc5d820b9e65018bed40d4b 612 SUPERFAMILY SSF53067 262 346 7.45E-19 T 23-04-2016 DC74_RS09140 182a05feefc5d820b9e65018bed40d4b 612 Pfam PF16861 Carbamoyltransferase C-terminus 403 593 1.1E-72 T 23-04-2016 IPR031730 Carbamoyltransferase, C-terminal DC74_RS38645 00382aa89fa4a975ec1855259fde38af 484 PIRSF PIRSF002744 5 482 4.6E-99 T 23-04-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 DC74_RS38645 00382aa89fa4a975ec1855259fde38af 484 PANTHER PTHR31806 21 484 3.9E-61 T 23-04-2016 DC74_RS38645 00382aa89fa4a975ec1855259fde38af 484 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 34 458 6.4E-40 T 23-04-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 DC74_RS22595 79ac66d89812f4b53828bf317379a9fe 172 PANTHER PTHR23091:SF259 8 136 3.5E-20 T 23-04-2016 DC74_RS22595 79ac66d89812f4b53828bf317379a9fe 172 Pfam PF00583 Acetyltransferase (GNAT) family 55 125 8.6E-11 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS22595 79ac66d89812f4b53828bf317379a9fe 172 PANTHER PTHR23091 8 136 3.5E-20 T 23-04-2016 DC74_RS22595 79ac66d89812f4b53828bf317379a9fe 172 SUPERFAMILY SSF55729 4 132 8.23E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS22595 79ac66d89812f4b53828bf317379a9fe 172 Gene3D G3DSA:3.40.630.30 8 150 1.3E-32 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS12135 78a692f36fa465e24875b1dd82aff32b 242 PANTHER PTHR34387:SF1 31 242 5.1E-15 T 23-04-2016 DC74_RS12135 78a692f36fa465e24875b1dd82aff32b 242 Pfam PF04402 Protein of unknown function (DUF541) 30 235 6.4E-35 T 23-04-2016 IPR007497 Protein of unknown function DUF541 DC74_RS12135 78a692f36fa465e24875b1dd82aff32b 242 PANTHER PTHR34387 31 242 5.1E-15 T 23-04-2016 DC74_RS06330 6412d8295c4356bbc39e7096dcacd04b 479 Gene3D G3DSA:3.40.50.200 80 472 1.7E-69 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS06330 6412d8295c4356bbc39e7096dcacd04b 479 SUPERFAMILY SSF52743 88 469 7.86E-41 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS06330 6412d8295c4356bbc39e7096dcacd04b 479 PANTHER PTHR14218 118 468 3.8E-31 T 23-04-2016 DC74_RS06330 6412d8295c4356bbc39e7096dcacd04b 479 Pfam PF00082 Subtilase family 155 411 9.6E-6 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS37580 612da7c74bbd9daf4830d31859a03654 142 SUPERFAMILY SSF54593 6 141 1.88E-8 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS37580 612da7c74bbd9daf4830d31859a03654 142 PANTHER PTHR35908:SF1 2 34 2.2E-42 T 23-04-2016 DC74_RS37580 612da7c74bbd9daf4830d31859a03654 142 PANTHER PTHR35908:SF1 51 141 2.2E-42 T 23-04-2016 DC74_RS37580 612da7c74bbd9daf4830d31859a03654 142 PANTHER PTHR35908 2 34 2.2E-42 T 23-04-2016 DC74_RS37580 612da7c74bbd9daf4830d31859a03654 142 PANTHER PTHR35908 51 141 2.2E-42 T 23-04-2016 DC74_RS37580 612da7c74bbd9daf4830d31859a03654 142 Gene3D G3DSA:3.10.180.10 9 141 1.7E-6 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS21065 3cc0c53d59da62e333c760487247645f 449 PANTHER PTHR10543:SF37 17 446 4.0E-127 T 23-04-2016 DC74_RS21065 3cc0c53d59da62e333c760487247645f 449 Pfam PF03055 Retinal pigment epithelial membrane protein 23 444 5.1E-100 T 23-04-2016 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 DC74_RS21065 3cc0c53d59da62e333c760487247645f 449 PANTHER PTHR10543 17 446 4.0E-127 T 23-04-2016 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 DC74_RS28590 80f8ac7d75926395a65a5a1c49a69b3e 156 Gene3D G3DSA:1.25.40.10 103 146 1.6E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS06025 89acdb717d822bb4046fd267c9d47cb3 348 Pfam PF12710 haloacid dehalogenase-like hydrolase 121 231 9.9E-7 T 23-04-2016 DC74_RS06025 89acdb717d822bb4046fd267c9d47cb3 348 SUPERFAMILY SSF56784 24 289 1.53E-13 T 23-04-2016 IPR023214 HAD-like domain DC74_RS06025 89acdb717d822bb4046fd267c9d47cb3 348 Gene3D G3DSA:3.40.50.1000 42 62 6.1E-9 T 23-04-2016 IPR023214 HAD-like domain DC74_RS06025 89acdb717d822bb4046fd267c9d47cb3 348 Gene3D G3DSA:3.40.50.1000 160 290 6.1E-9 T 23-04-2016 IPR023214 HAD-like domain DC74_RS07075 0f075a93d1b5afc7a689f926afef6cd7 216 PANTHER PTHR11080:SF38 2 210 1.4E-50 T 23-04-2016 DC74_RS07075 0f075a93d1b5afc7a689f926afef6cd7 216 Pfam PF00857 Isochorismatase family 28 205 3.4E-35 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS07075 0f075a93d1b5afc7a689f926afef6cd7 216 Gene3D G3DSA:3.40.50.850 24 212 4.1E-46 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS07075 0f075a93d1b5afc7a689f926afef6cd7 216 PANTHER PTHR11080 2 210 1.4E-50 T 23-04-2016 DC74_RS07075 0f075a93d1b5afc7a689f926afef6cd7 216 SUPERFAMILY SSF52499 15 210 8.63E-47 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 DC74_RS29300 07bcea0076b9a6fe085bcf20a63e9ab3 287 PRINTS PR00164 ABC-2 type transport system membrane protein signature 91 113 3.0E-8 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS29300 07bcea0076b9a6fe085bcf20a63e9ab3 287 PRINTS PR00164 ABC-2 type transport system membrane protein signature 231 250 3.0E-8 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS29300 07bcea0076b9a6fe085bcf20a63e9ab3 287 PRINTS PR00164 ABC-2 type transport system membrane protein signature 211 230 3.0E-8 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS29300 07bcea0076b9a6fe085bcf20a63e9ab3 287 PRINTS PR00164 ABC-2 type transport system membrane protein signature 174 198 3.0E-8 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS29300 07bcea0076b9a6fe085bcf20a63e9ab3 287 PIRSF PIRSF006648 10 286 1.3E-60 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS29300 07bcea0076b9a6fe085bcf20a63e9ab3 287 PANTHER PTHR30294 49 285 1.4E-44 T 23-04-2016 DC74_RS29300 07bcea0076b9a6fe085bcf20a63e9ab3 287 Pfam PF01061 ABC-2 type transporter 45 253 1.9E-35 T 23-04-2016 IPR013525 ABC-2 type transporter GO:0016020 DC74_RS29300 07bcea0076b9a6fe085bcf20a63e9ab3 287 PANTHER PTHR30294:SF4 49 285 1.4E-44 T 23-04-2016 DC74_RS27480 21c2699b8a2774a4b6d8fb0dd567ff40 256 Pfam PF14581 SseB protein C-terminal domain 137 253 1.2E-20 T 23-04-2016 IPR027945 SseB protein, C-terminal DC74_RS27480 21c2699b8a2774a4b6d8fb0dd567ff40 256 Pfam PF07179 SseB protein N-terminal domain 8 122 3.0E-15 T 23-04-2016 IPR009839 SseB protein N-terminal domain DC74_RS32230 283208065225f668ea684ec1a01096e6 364 PANTHER PTHR32347 183 359 8.4E-12 T 23-04-2016 DC74_RS32230 283208065225f668ea684ec1a01096e6 364 Pfam PF01471 Putative peptidoglycan binding domain 127 180 1.8E-11 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS32230 283208065225f668ea684ec1a01096e6 364 SUPERFAMILY SSF47090 116 180 2.16E-13 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS32230 283208065225f668ea684ec1a01096e6 364 Gene3D G3DSA:1.10.101.10 119 178 4.3E-15 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS32230 283208065225f668ea684ec1a01096e6 364 Pfam PF13437 HlyD family secretion protein 183 282 3.2E-5 T 23-04-2016 DC74_RS12715 3527fa0ffe286f662eab5968d4693b5b 449 PANTHER PTHR21337 12 449 6.6E-282 T 23-04-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 DC74_RS12715 3527fa0ffe286f662eab5968d4693b5b 449 Pfam PF01474 Class-II DAHP synthetase family 12 443 3.7E-203 T 23-04-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 DC74_RS12715 3527fa0ffe286f662eab5968d4693b5b 449 SUPERFAMILY SSF51569 10 447 8.06E-200 T 23-04-2016 DC74_RS12715 3527fa0ffe286f662eab5968d4693b5b 449 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 11 449 2.2E-237 T 23-04-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 DC74_RS15820 5974c6e417e34580ada8449edb6c0865 263 Pfam PF00005 ABC transporter 26 182 3.6E-9 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS15820 5974c6e417e34580ada8449edb6c0865 263 SUPERFAMILY SSF52540 12 217 1.55E-22 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS15820 5974c6e417e34580ada8449edb6c0865 263 Gene3D G3DSA:3.40.50.300 5 215 1.1E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28480 4c0f628c24210e49370985d3e268eea9 509 PANTHER PTHR40765 190 509 1.4E-33 T 23-04-2016 DC74_RS28480 4c0f628c24210e49370985d3e268eea9 509 PANTHER PTHR40765 1 174 1.4E-33 T 23-04-2016 DC74_RS28480 4c0f628c24210e49370985d3e268eea9 509 PANTHER PTHR40765:SF1 190 509 1.4E-33 T 23-04-2016 DC74_RS28480 4c0f628c24210e49370985d3e268eea9 509 PANTHER PTHR40765:SF1 1 174 1.4E-33 T 23-04-2016 DC74_RS28480 4c0f628c24210e49370985d3e268eea9 509 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 2 503 9.4E-58 T 23-04-2016 IPR007795 Type VII secretion system EccB DC74_RS04720 041002d2461ed674bff6e45fbe1bfadb 243 Gene3D G3DSA:3.40.50.720 1 197 1.5E-23 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04720 041002d2461ed674bff6e45fbe1bfadb 243 SUPERFAMILY SSF51735 1 200 6.81E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04720 041002d2461ed674bff6e45fbe1bfadb 243 Pfam PF13460 NAD(P)H-binding 7 172 8.9E-9 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS04720 041002d2461ed674bff6e45fbe1bfadb 243 PANTHER PTHR14194:SF69 1 242 4.7E-107 T 23-04-2016 DC74_RS04720 041002d2461ed674bff6e45fbe1bfadb 243 PANTHER PTHR14194 1 242 4.7E-107 T 23-04-2016 DC74_RS20645 af143aa268590313112d9ecb42c23f27 610 SMART SM00327 18 206 8.0E-14 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS20645 af143aa268590313112d9ecb42c23f27 610 Gene3D G3DSA:3.40.50.410 21 201 2.0E-14 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS20645 af143aa268590313112d9ecb42c23f27 610 Pfam PF00092 von Willebrand factor type A domain 21 198 1.0E-10 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS20645 af143aa268590313112d9ecb42c23f27 610 SUPERFAMILY SSF53300 20 203 2.67E-21 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS26825 ac430810d8b0242670e56a5b07d503e5 676 Pfam PF02342 TerD domain 2 175 2.3E-45 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS26825 ac430810d8b0242670e56a5b07d503e5 676 PANTHER PTHR32097 390 528 4.8E-153 T 23-04-2016 DC74_RS26825 ac430810d8b0242670e56a5b07d503e5 676 PANTHER PTHR32097 2 326 4.8E-153 T 23-04-2016 DC74_RS26825 ac430810d8b0242670e56a5b07d503e5 676 PANTHER PTHR32097:SF4 390 528 4.8E-153 T 23-04-2016 DC74_RS26825 ac430810d8b0242670e56a5b07d503e5 676 PANTHER PTHR32097:SF4 2 326 4.8E-153 T 23-04-2016 DC74_RS26825 ac430810d8b0242670e56a5b07d503e5 676 Gene3D G3DSA:2.60.60.30 19 172 9.3E-34 T 23-04-2016 DC74_RS23300 3465c264d7018159f3e4236e3c138253 226 SMART SM00448 2 112 1.7E-44 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS23300 3465c264d7018159f3e4236e3c138253 226 Gene3D G3DSA:3.40.50.2300 3 121 6.9E-40 T 23-04-2016 DC74_RS23300 3465c264d7018159f3e4236e3c138253 226 SUPERFAMILY SSF52172 3 125 5.41E-41 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS23300 3465c264d7018159f3e4236e3c138253 226 Pfam PF00072 Response regulator receiver domain 4 113 7.1E-28 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS23300 3465c264d7018159f3e4236e3c138253 226 PANTHER PTHR26402:SF459 2 226 1.3E-174 T 23-04-2016 DC74_RS23300 3465c264d7018159f3e4236e3c138253 226 Gene3D G3DSA:1.10.10.10 127 225 3.3E-36 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23300 3465c264d7018159f3e4236e3c138253 226 SMART SM00862 148 224 7.5E-30 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS23300 3465c264d7018159f3e4236e3c138253 226 SUPERFAMILY SSF46894 124 225 1.39E-31 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS23300 3465c264d7018159f3e4236e3c138253 226 PANTHER PTHR26402 2 226 1.3E-174 T 23-04-2016 DC74_RS23300 3465c264d7018159f3e4236e3c138253 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 1.3E-27 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS23125 415d541b7c9f329774ad4b903f69f3f9 151 Pfam PF01475 Ferric uptake regulator family 13 105 1.2E-22 T 23-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 DC74_RS23125 415d541b7c9f329774ad4b903f69f3f9 151 PANTHER PTHR33202:SF7 5 139 2.4E-34 T 23-04-2016 DC74_RS23125 415d541b7c9f329774ad4b903f69f3f9 151 SUPERFAMILY SSF46785 6 134 4.42E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23125 415d541b7c9f329774ad4b903f69f3f9 151 PANTHER PTHR33202 5 139 2.4E-34 T 23-04-2016 DC74_RS23125 415d541b7c9f329774ad4b903f69f3f9 151 Gene3D G3DSA:1.10.10.10 5 82 5.4E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 0.0058 T 23-04-2016 DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 SUPERFAMILY SSF51735 1 256 5.94E-65 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 Gene3D G3DSA:3.40.50.720 1 256 2.5E-69 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.7E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.7E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.7E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.7E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.7E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.7E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.1E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.1E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.1E-9 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 PANTHER PTHR24322 157 188 8.3E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 PANTHER PTHR24322 11 141 8.3E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10840 02cec02fa95a63444f6e188aed4ef54c 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 255 1.9E-50 T 23-04-2016 DC74_RS03375 6afde8a0b5ee110920839582fede86aa 79 SUPERFAMILY SSF53098 17 69 6.37E-8 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS03375 6afde8a0b5ee110920839582fede86aa 79 Pfam PF01609 Transposase DDE domain 12 59 1.7E-6 T 23-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 DC74_RS04235 f80c35d7b182e0bf696e7da18d6b9eec 323 Pfam PF01145 SPFH domain / Band 7 family 69 239 1.2E-17 T 23-04-2016 IPR001107 Band 7 domain DC74_RS04235 f80c35d7b182e0bf696e7da18d6b9eec 323 SUPERFAMILY SSF117892 101 230 5.1E-6 T 23-04-2016 IPR001107 Band 7 domain DC74_RS04235 f80c35d7b182e0bf696e7da18d6b9eec 323 PANTHER PTHR10264 49 230 1.6E-45 T 23-04-2016 IPR001972 Stomatin family GO:0016020 DC74_RS04235 f80c35d7b182e0bf696e7da18d6b9eec 323 PANTHER PTHR10264:SF46 49 230 1.6E-45 T 23-04-2016 DC74_RS30800 d03daa88b1bcc1604938b57fc75d8a44 324 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 60 320 5.6E-59 T 23-04-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain DC74_RS30800 d03daa88b1bcc1604938b57fc75d8a44 324 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 60 319 9.7E-41 T 23-04-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain DC74_RS09655 ebeb7b446ca26768bc684ef1e588e3a5 217 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 6.2E-10 T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS09655 ebeb7b446ca26768bc684ef1e588e3a5 217 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS04605 38dad4c1db2245d93bd31663c3d9ca74 108 Pfam PF13586 Transposase DDE domain 7 80 3.2E-8 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS34635 b66edb0c0da4c5960a5595698f6eab9f 162 Gene3D G3DSA:3.30.565.10 74 134 5.7E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS34635 b66edb0c0da4c5960a5595698f6eab9f 162 Pfam PF13581 Histidine kinase-like ATPase domain 46 156 6.7E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS34635 b66edb0c0da4c5960a5595698f6eab9f 162 SUPERFAMILY SSF55874 55 143 9.04E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS37980 64fe7b09a85c4ebcdd2823e085836b8e 314 SUPERFAMILY SSF51735 10 308 6.55E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37980 64fe7b09a85c4ebcdd2823e085836b8e 314 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 208 1.1E-9 T 23-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 DC74_RS37980 64fe7b09a85c4ebcdd2823e085836b8e 314 Gene3D G3DSA:3.40.50.720 10 248 9.1E-18 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS37980 64fe7b09a85c4ebcdd2823e085836b8e 314 PANTHER PTHR10366 266 308 8.9E-17 T 23-04-2016 DC74_RS37980 64fe7b09a85c4ebcdd2823e085836b8e 314 PANTHER PTHR10366 13 250 8.9E-17 T 23-04-2016 DC74_RS38725 45f67cd91ebce4b8e683ffd661af4885 63 SUPERFAMILY SSF54862 2 60 8.37E-12 T 23-04-2016 DC74_RS38725 45f67cd91ebce4b8e683ffd661af4885 63 Pfam PF06902 Divergent 4Fe-4S mono-cluster 1 61 1.8E-12 T 23-04-2016 IPR010693 Divergent 4Fe-4S mono-cluster DC74_RS38725 45f67cd91ebce4b8e683ffd661af4885 63 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.2E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS38725 45f67cd91ebce4b8e683ffd661af4885 63 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.2E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS38725 45f67cd91ebce4b8e683ffd661af4885 63 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 1.2E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS38725 45f67cd91ebce4b8e683ffd661af4885 63 Gene3D G3DSA:3.30.70.20 2 61 7.2E-16 T 23-04-2016 DC74_RS38725 45f67cd91ebce4b8e683ffd661af4885 63 PANTHER PTHR36923 1 61 3.1E-19 T 23-04-2016 DC74_RS38725 45f67cd91ebce4b8e683ffd661af4885 63 PANTHER PTHR36923:SF1 1 61 3.1E-19 T 23-04-2016 DC74_RS12540 83eb9dd9172a7f0076fc328dc09613d8 363 PANTHER PTHR21015 3 362 9.4E-114 T 23-04-2016 DC74_RS12540 83eb9dd9172a7f0076fc328dc09613d8 363 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 4.2E-43 T 23-04-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS12540 83eb9dd9172a7f0076fc328dc09613d8 363 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 351 6.1E-87 T 23-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS12540 83eb9dd9172a7f0076fc328dc09613d8 363 Gene3D G3DSA:3.40.50.2000 187 343 5.6E-19 T 23-04-2016 DC74_RS12540 83eb9dd9172a7f0076fc328dc09613d8 363 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 358 31.95 T 23-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS12540 83eb9dd9172a7f0076fc328dc09613d8 363 SUPERFAMILY SSF53756 2 359 7.4E-101 T 23-04-2016 DC74_RS12540 83eb9dd9172a7f0076fc328dc09613d8 363 PANTHER PTHR21015:SF22 3 362 9.4E-114 T 23-04-2016 DC74_RS12540 83eb9dd9172a7f0076fc328dc09613d8 363 Gene3D G3DSA:3.40.50.2000 2 186 3.2E-61 T 23-04-2016 DC74_RS12540 83eb9dd9172a7f0076fc328dc09613d8 363 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 348 2.0E-38 T 23-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 DC74_RS39130 cb2046c96b9bbf2e0d8bd6b07abb951b 173 SUPERFAMILY SSF109854 29 163 9.92E-20 T 23-04-2016 DC74_RS39130 cb2046c96b9bbf2e0d8bd6b07abb951b 173 Pfam PF12867 DinB superfamily 30 160 1.9E-11 T 23-04-2016 IPR024775 DinB-like domain DC74_RS39130 cb2046c96b9bbf2e0d8bd6b07abb951b 173 Gene3D G3DSA:1.20.120.450 33 162 3.4E-13 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS28680 c826e158d3161cfc83a76e9693aca09f 178 Gene3D G3DSA:3.90.950.20 8 160 7.5E-55 T 23-04-2016 IPR008136 CinA, C-terminal DC74_RS28680 c826e158d3161cfc83a76e9693aca09f 178 SUPERFAMILY SSF142433 10 158 1.02E-44 T 23-04-2016 IPR008136 CinA, C-terminal DC74_RS28680 c826e158d3161cfc83a76e9693aca09f 178 Pfam PF02464 Competence-damaged protein 11 156 9.6E-48 T 23-04-2016 IPR008136 CinA, C-terminal DC74_RS28680 c826e158d3161cfc83a76e9693aca09f 178 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 16 155 7.8E-37 T 23-04-2016 IPR008136 CinA, C-terminal DC74_RS28680 c826e158d3161cfc83a76e9693aca09f 178 PANTHER PTHR13939 13 166 1.1E-52 T 23-04-2016 DC74_RS27125 7d548422a484476e070080cc5dfc263e 428 Gene3D G3DSA:3.40.50.300 1 222 1.2E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27125 7d548422a484476e070080cc5dfc263e 428 SMART SM00382 26 213 7.9E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS27125 7d548422a484476e070080cc5dfc263e 428 PANTHER PTHR24220 302 313 2.2E-123 T 23-04-2016 DC74_RS27125 7d548422a484476e070080cc5dfc263e 428 PANTHER PTHR24220 3 219 2.2E-123 T 23-04-2016 DC74_RS27125 7d548422a484476e070080cc5dfc263e 428 PANTHER PTHR24220:SF523 302 313 2.2E-123 T 23-04-2016 DC74_RS27125 7d548422a484476e070080cc5dfc263e 428 PANTHER PTHR24220:SF523 3 219 2.2E-123 T 23-04-2016 DC74_RS27125 7d548422a484476e070080cc5dfc263e 428 Pfam PF00005 ABC transporter 18 156 3.0E-24 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS27125 7d548422a484476e070080cc5dfc263e 428 SUPERFAMILY SSF52540 2 218 1.74E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS31840 be86c2d66898e113f109bca5e4a1de55 168 Pfam PF10400 Virulence activator alpha C-term 91 167 7.7E-9 T 23-04-2016 IPR018309 Transcription regulator PadR, C-terminal DC74_RS31840 be86c2d66898e113f109bca5e4a1de55 168 PANTHER PTHR33169:SF2 1 167 5.3E-24 T 23-04-2016 DC74_RS31840 be86c2d66898e113f109bca5e4a1de55 168 Pfam PF03551 Transcriptional regulator PadR-like family 5 79 5.8E-19 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS31840 be86c2d66898e113f109bca5e4a1de55 168 Gene3D G3DSA:1.10.10.10 2 84 4.4E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31840 be86c2d66898e113f109bca5e4a1de55 168 SUPERFAMILY SSF46785 2 167 4.24E-35 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS31840 be86c2d66898e113f109bca5e4a1de55 168 PANTHER PTHR33169 1 167 5.3E-24 T 23-04-2016 DC74_RS39400 011ef45b861e8c53051b7156e521c358 341 SUPERFAMILY SSF51445 61 300 5.21E-19 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS39400 011ef45b861e8c53051b7156e521c358 341 Gene3D G3DSA:3.20.20.80 88 299 4.0E-9 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS14930 69b53de8a941673e58bf96845a59a647 363 PANTHER PTHR33794 17 361 4.1E-132 T 23-04-2016 DC74_RS14930 69b53de8a941673e58bf96845a59a647 363 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 143 163 1.2E-28 T 23-04-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 DC74_RS14930 69b53de8a941673e58bf96845a59a647 363 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 200 211 1.2E-28 T 23-04-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 DC74_RS14930 69b53de8a941673e58bf96845a59a647 363 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 281 297 1.2E-28 T 23-04-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 DC74_RS14930 69b53de8a941673e58bf96845a59a647 363 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 179 195 1.2E-28 T 23-04-2016 IPR023612 Peptidase M4 GO:0004222|GO:0006508 DC74_RS14930 69b53de8a941673e58bf96845a59a647 363 Gene3D G3DSA:1.10.390.10 193 360 7.9E-57 T 23-04-2016 DC74_RS14930 69b53de8a941673e58bf96845a59a647 363 SUPERFAMILY SSF55486 74 360 5.49E-86 T 23-04-2016 DC74_RS14930 69b53de8a941673e58bf96845a59a647 363 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 79 188 3.1E-30 T 23-04-2016 IPR013856 Peptidase M4 domain GO:0004222 DC74_RS14930 69b53de8a941673e58bf96845a59a647 363 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 191 360 1.6E-56 T 23-04-2016 IPR001570 Peptidase M4, C-terminal GO:0004222 DC74_RS14930 69b53de8a941673e58bf96845a59a647 363 Gene3D G3DSA:3.10.170.10 73 192 2.9E-44 T 23-04-2016 IPR013856 Peptidase M4 domain GO:0004222 DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 SUPERFAMILY SSF88659 157 215 1.64E-11 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 SUPERFAMILY SSF88946 42 117 1.92E-22 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 Gene3D G3DSA:3.10.450.50 230 342 1.1E-19 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 Pfam PF04542 Sigma-70 region 2 43 108 4.0E-20 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 PANTHER PTHR30173 12 342 9.5E-128 T 23-04-2016 DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 Pfam PF12680 SnoaL-like domain 238 328 5.7E-7 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 PANTHER PTHR30173:SF22 12 342 9.5E-128 T 23-04-2016 DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 Gene3D G3DSA:1.10.1740.10 42 119 1.5E-24 T 23-04-2016 DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 SUPERFAMILY SSF54427 229 340 1.55E-18 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 Gene3D G3DSA:1.10.10.10 156 216 1.3E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 40 214 3.1E-24 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 Pfam PF08281 Sigma-70, region 4 162 214 7.5E-13 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS17260 5ad7863a818296095ff20a623d7b7a82 350 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 37 344 1.8E-121 T 23-04-2016 IPR014305 RNA polymerase sigma-G type, actinobacteria DC74_RS34270 6a1bf9c299ae6633471bd60c7db88f58 175 SUPERFAMILY SSF55729 29 150 6.1E-24 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS34270 6a1bf9c299ae6633471bd60c7db88f58 175 Gene3D G3DSA:3.40.630.30 14 148 7.2E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS34270 6a1bf9c299ae6633471bd60c7db88f58 175 Pfam PF13527 Acetyltransferase (GNAT) domain 44 132 3.5E-14 T 23-04-2016 DC74_RS39190 284f2927a5a4e805fbee7e9b6bbd3f47 482 Pfam PF09594 Protein of unknown function (DUF2029) 159 385 1.2E-11 T 23-04-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 DC74_RS21515 cade1ce2842c07acd5ecb56aacdd9645 258 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 52 3.2E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS21515 cade1ce2842c07acd5ecb56aacdd9645 258 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 60 83 3.2E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS21515 cade1ce2842c07acd5ecb56aacdd9645 258 PANTHER PTHR30328:SF17 11 146 3.0E-33 T 23-04-2016 DC74_RS21515 cade1ce2842c07acd5ecb56aacdd9645 258 SUPERFAMILY SSF48498 105 256 7.0E-25 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS21515 cade1ce2842c07acd5ecb56aacdd9645 258 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 102 251 6.2E-12 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS21515 cade1ce2842c07acd5ecb56aacdd9645 258 PANTHER PTHR30328 11 146 3.0E-33 T 23-04-2016 DC74_RS21515 cade1ce2842c07acd5ecb56aacdd9645 258 SUPERFAMILY SSF46689 35 93 7.98E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS21515 cade1ce2842c07acd5ecb56aacdd9645 258 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 83 6.0E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS21515 cade1ce2842c07acd5ecb56aacdd9645 258 Gene3D G3DSA:1.10.357.10 25 256 7.3E-58 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS21515 cade1ce2842c07acd5ecb56aacdd9645 258 PRINTS PR00400 Tetracycline repressor protein signature 162 181 4.9E-6 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS21515 cade1ce2842c07acd5ecb56aacdd9645 258 PRINTS PR00400 Tetracycline repressor protein signature 51 74 4.9E-6 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS21515 cade1ce2842c07acd5ecb56aacdd9645 258 PRINTS PR00400 Tetracycline repressor protein signature 106 125 4.9E-6 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS32745 463d9395c5c1390b5ad6666fc82d499b 480 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 80 218 2.2E-15 T 23-04-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 DC74_RS32745 463d9395c5c1390b5ad6666fc82d499b 480 SUPERFAMILY SSF55931 306 320 4.61E-31 T 23-04-2016 DC74_RS32745 463d9395c5c1390b5ad6666fc82d499b 480 SUPERFAMILY SSF55931 14 33 4.61E-31 T 23-04-2016 DC74_RS32745 463d9395c5c1390b5ad6666fc82d499b 480 SUPERFAMILY SSF55931 76 257 4.61E-31 T 23-04-2016 DC74_RS32745 463d9395c5c1390b5ad6666fc82d499b 480 SUPERFAMILY SSF55931 349 463 4.61E-31 T 23-04-2016 DC74_RS30645 d36c3a89f68b82949f904b24712e8e77 488 Gene3D G3DSA:1.50.10.20 13 72 8.2E-11 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS30645 d36c3a89f68b82949f904b24712e8e77 488 Gene3D G3DSA:1.50.10.20 184 354 8.2E-11 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS30645 d36c3a89f68b82949f904b24712e8e77 488 SUPERFAMILY SSF48239 11 226 2.51E-10 T 23-04-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid DC74_RS29220 27142f24d97f10f05fcefc6b12d25b3a 116 PIRSF PIRSF006910 1 113 3.8E-49 T 23-04-2016 IPR016499 Nucleic acid binding protein, Rv2694c, predicted DC74_RS29220 27142f24d97f10f05fcefc6b12d25b3a 116 Gene3D G3DSA:2.40.50.140 27 110 1.5E-7 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS13645 ca985b9128e6558b3ebe44a60ac13098 461 PANTHER PTHR12526:SF397 24 70 1.8E-81 T 23-04-2016 DC74_RS13645 ca985b9128e6558b3ebe44a60ac13098 461 SUPERFAMILY SSF53756 30 447 7.63E-78 T 23-04-2016 DC74_RS13645 ca985b9128e6558b3ebe44a60ac13098 461 PANTHER PTHR12526:SF397 105 449 1.8E-81 T 23-04-2016 DC74_RS13645 ca985b9128e6558b3ebe44a60ac13098 461 Gene3D G3DSA:3.40.50.2000 238 424 5.6E-26 T 23-04-2016 DC74_RS13645 ca985b9128e6558b3ebe44a60ac13098 461 Pfam PF00534 Glycosyl transferases group 1 268 424 6.9E-28 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 DC74_RS13645 ca985b9128e6558b3ebe44a60ac13098 461 Pfam PF13439 Glycosyltransferase Family 4 43 254 5.7E-28 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain DC74_RS13645 ca985b9128e6558b3ebe44a60ac13098 461 PANTHER PTHR12526 24 70 1.8E-81 T 23-04-2016 DC74_RS13645 ca985b9128e6558b3ebe44a60ac13098 461 PANTHER PTHR12526 105 449 1.8E-81 T 23-04-2016 DC74_RS12040 1c927d9482035b87b5ae3e8a4919f822 333 Gene3D G3DSA:2.160.20.10 47 303 2.2E-28 T 23-04-2016 IPR012334 Pectin lyase fold DC74_RS12040 1c927d9482035b87b5ae3e8a4919f822 333 SMART SM00710 112 133 990.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS12040 1c927d9482035b87b5ae3e8a4919f822 333 SMART SM00710 276 303 3100.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS12040 1c927d9482035b87b5ae3e8a4919f822 333 SMART SM00710 134 156 2000.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS12040 1c927d9482035b87b5ae3e8a4919f822 333 SMART SM00710 219 241 1700.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS12040 1c927d9482035b87b5ae3e8a4919f822 333 SMART SM00710 158 186 8.6 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS12040 1c927d9482035b87b5ae3e8a4919f822 333 SMART SM00710 248 270 2200.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS12040 1c927d9482035b87b5ae3e8a4919f822 333 Pfam PF13229 Right handed beta helix region 102 264 7.1E-8 T 23-04-2016 DC74_RS12040 1c927d9482035b87b5ae3e8a4919f822 333 SUPERFAMILY SSF51126 47 323 8.96E-34 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS31120 8a5277a517f1dbd69dd2de61dbcac916 127 Pfam PF13581 Histidine kinase-like ATPase domain 8 120 1.9E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS31120 8a5277a517f1dbd69dd2de61dbcac916 127 Gene3D G3DSA:3.30.565.10 18 122 3.9E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS31120 8a5277a517f1dbd69dd2de61dbcac916 127 SUPERFAMILY SSF55874 28 122 2.3E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS31175 6c9de67a8b62ad3d7a7dcbe5b3e8bb22 397 Pfam PF13478 XdhC Rossmann domain 221 363 6.2E-40 T 23-04-2016 IPR027051 XdhC Rossmann domain DC74_RS31175 6c9de67a8b62ad3d7a7dcbe5b3e8bb22 397 PANTHER PTHR30388 186 387 2.7E-137 T 23-04-2016 DC74_RS31175 6c9de67a8b62ad3d7a7dcbe5b3e8bb22 397 PANTHER PTHR30388 1 121 2.7E-137 T 23-04-2016 DC74_RS31175 6c9de67a8b62ad3d7a7dcbe5b3e8bb22 397 PANTHER PTHR30388:SF4 186 387 2.7E-137 T 23-04-2016 DC74_RS31175 6c9de67a8b62ad3d7a7dcbe5b3e8bb22 397 PANTHER PTHR30388:SF4 1 121 2.7E-137 T 23-04-2016 DC74_RS31175 6c9de67a8b62ad3d7a7dcbe5b3e8bb22 397 Pfam PF02625 XdhC and CoxI family 134 198 6.0E-14 T 23-04-2016 IPR003777 XdhC- CoxI DC74_RS31175 6c9de67a8b62ad3d7a7dcbe5b3e8bb22 397 Pfam PF02625 XdhC and CoxI family 11 78 3.1E-24 T 23-04-2016 IPR003777 XdhC- CoxI DC74_RS07225 9ec92cb6e3081e8a605256352095de7b 143 Pfam PF06841 T4-like virus tail tube protein gp19 65 129 2.1E-8 T 23-04-2016 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 DC74_RS14750 7831067a25d0c6ca7f15d8879dc3eb56 300 PANTHER PTHR30193 6 300 2.4E-67 T 23-04-2016 DC74_RS14750 7831067a25d0c6ca7f15d8879dc3eb56 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 289 3.1E-8 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS14750 7831067a25d0c6ca7f15d8879dc3eb56 300 Gene3D G3DSA:1.10.3720.10 59 294 4.0E-48 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS14750 7831067a25d0c6ca7f15d8879dc3eb56 300 SUPERFAMILY SSF161098 53 287 9.68E-43 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS14750 7831067a25d0c6ca7f15d8879dc3eb56 300 PANTHER PTHR30193:SF6 6 300 2.4E-67 T 23-04-2016 DC74_RS26590 a60a2def60f7d0f0150e7d5bc32b2b5c 122 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 18.289 T 23-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 DC74_RS26590 a60a2def60f7d0f0150e7d5bc32b2b5c 122 PANTHER PTHR28259 1 119 7.8E-33 T 23-04-2016 DC74_RS26590 a60a2def60f7d0f0150e7d5bc32b2b5c 122 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 115 1.5E-21 T 23-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 DC74_RS26590 a60a2def60f7d0f0150e7d5bc32b2b5c 122 TIGRFAM TIGR00494 crcB: protein CrcB 4 117 7.8E-25 T 23-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 DC74_RS34880 463f032e4c6c2e117d646a6ef676eff2 353 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 180 1.7E-32 T 23-04-2016 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: REACT_216|Reactome: REACT_6185 DC74_RS34880 463f032e4c6c2e117d646a6ef676eff2 353 PIRSF PIRSF006493 1 291 5.4E-73 T 23-04-2016 IPR009187 Non-homologous end joining protein Ku, prokaryotic type DC74_RS34880 463f032e4c6c2e117d646a6ef676eff2 353 PANTHER PTHR41251:SF1 1 309 8.4E-75 T 23-04-2016 DC74_RS34880 463f032e4c6c2e117d646a6ef676eff2 353 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 254 29.466 T 23-04-2016 IPR009187 Non-homologous end joining protein Ku, prokaryotic type DC74_RS34880 463f032e4c6c2e117d646a6ef676eff2 353 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 255 1.4E-78 T 23-04-2016 IPR009187 Non-homologous end joining protein Ku, prokaryotic type DC74_RS34880 463f032e4c6c2e117d646a6ef676eff2 353 Gene3D G3DSA:2.40.290.10 4 153 7.7E-10 T 23-04-2016 IPR016194 SPOC-like, C-terminal domain DC74_RS34880 463f032e4c6c2e117d646a6ef676eff2 353 SMART SM00559 53 183 1.6E-30 T 23-04-2016 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: REACT_216|Reactome: REACT_6185 DC74_RS34880 463f032e4c6c2e117d646a6ef676eff2 353 PANTHER PTHR41251 1 309 8.4E-75 T 23-04-2016 DC74_RS34880 463f032e4c6c2e117d646a6ef676eff2 353 SUPERFAMILY SSF100939 1 255 6.87E-43 T 23-04-2016 IPR016194 SPOC-like, C-terminal domain DC74_RS16095 b8dcbadd55b000fe85577e54e92b3dfd 166 SUPERFAMILY SSF50891 7 151 2.69E-10 T 23-04-2016 IPR029000 Cyclophilin-like domain DC74_RS16095 b8dcbadd55b000fe85577e54e92b3dfd 166 Pfam PF12903 Protein of unknown function (DUF3830) 8 165 5.1E-64 T 23-04-2016 IPR024532 Protein of unknown function DUF3830 DC74_RS38560 906d7d6f92188127da825f4093dd2908 352 SUPERFAMILY SSF50022 13 135 4.84E-33 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS38560 906d7d6f92188127da825f4093dd2908 352 PANTHER PTHR21266 24 344 2.1E-44 T 23-04-2016 DC74_RS38560 906d7d6f92188127da825f4093dd2908 352 PANTHER PTHR21266:SF19 24 344 2.1E-44 T 23-04-2016 DC74_RS38560 906d7d6f92188127da825f4093dd2908 352 SUPERFAMILY SSF55961 138 346 1.26E-25 T 23-04-2016 DC74_RS38560 906d7d6f92188127da825f4093dd2908 352 Gene3D G3DSA:2.102.10.10 26 140 9.5E-31 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS38560 906d7d6f92188127da825f4093dd2908 352 Pfam PF00355 Rieske [2Fe-2S] domain 27 107 2.2E-16 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS38670 5eb6e41710f0bbb9bd35440422d257d8 289 Pfam PF01738 Dienelactone hydrolase family 28 151 9.5E-7 T 23-04-2016 IPR002925 Dienelactone hydrolase GO:0016787 DC74_RS38670 5eb6e41710f0bbb9bd35440422d257d8 289 SUPERFAMILY SSF53474 26 226 6.19E-10 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS38670 5eb6e41710f0bbb9bd35440422d257d8 289 Gene3D G3DSA:3.40.50.1820 26 268 1.6E-13 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS39480 603c563b30b580d302a5e3cda165b646 362 PANTHER PTHR30106 25 362 1.7E-96 T 23-04-2016 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 DC74_RS39480 603c563b30b580d302a5e3cda165b646 362 Pfam PF03601 Conserved hypothetical protein 698 30 341 5.6E-69 T 23-04-2016 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 DC74_RS39480 603c563b30b580d302a5e3cda165b646 362 PANTHER PTHR30106:SF1 25 362 1.7E-96 T 23-04-2016 DC74_RS01245 f0ffacfb63e454093c218ac7140178d8 127 Gene3D G3DSA:3.10.180.10 8 116 1.0E-10 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS01245 f0ffacfb63e454093c218ac7140178d8 127 SUPERFAMILY SSF54593 6 116 1.98E-12 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS01245 f0ffacfb63e454093c218ac7140178d8 127 PANTHER PTHR35908:SF1 1 127 1.9E-29 T 23-04-2016 DC74_RS01245 f0ffacfb63e454093c218ac7140178d8 127 PANTHER PTHR35908 1 127 1.9E-29 T 23-04-2016 DC74_RS39630 33f6eed2d2a92d09aa907d9d30c7f39d 144 Gene3D G3DSA:3.10.180.10 9 143 3.3E-7 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS39630 33f6eed2d2a92d09aa907d9d30c7f39d 144 SUPERFAMILY SSF54593 8 143 6.08E-9 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS39630 33f6eed2d2a92d09aa907d9d30c7f39d 144 PANTHER PTHR35908 2 34 7.7E-42 T 23-04-2016 DC74_RS39630 33f6eed2d2a92d09aa907d9d30c7f39d 144 PANTHER PTHR35908 51 143 7.7E-42 T 23-04-2016 DC74_RS39630 33f6eed2d2a92d09aa907d9d30c7f39d 144 PANTHER PTHR35908:SF1 2 34 7.7E-42 T 23-04-2016 DC74_RS39630 33f6eed2d2a92d09aa907d9d30c7f39d 144 PANTHER PTHR35908:SF1 51 143 7.7E-42 T 23-04-2016 DC74_RS15595 037fa565299cfe42e3f9570d06b66a7b 466 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 427 461 1.4E-4 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain DC74_RS15595 037fa565299cfe42e3f9570d06b66a7b 466 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 119 166 1.5E-16 T 23-04-2016 IPR023849 Uncharacterised domain CHP03934, TQXA DC74_RS09670 854a17abc990e1cb0857a3dabcfdd721 399 PANTHER PTHR13833 247 326 2.7E-17 T 23-04-2016 DC74_RS09670 854a17abc990e1cb0857a3dabcfdd721 399 PANTHER PTHR13833 89 200 2.7E-17 T 23-04-2016 DC74_RS09670 854a17abc990e1cb0857a3dabcfdd721 399 SUPERFAMILY SSF51004 86 380 9.68E-65 T 23-04-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain DC74_RS09670 854a17abc990e1cb0857a3dabcfdd721 399 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 90 125 1.2E-12 T 23-04-2016 IPR011964 YVTN beta-propeller repeat DC74_RS09670 854a17abc990e1cb0857a3dabcfdd721 399 Gene3D G3DSA:2.130.10.10 87 386 2.2E-60 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS21230 0ce57e461a043fe06bb4f0f9778c9731 170 Pfam PF05534 HicB family 113 142 1.7E-4 T 23-04-2016 IPR008651 Uncharacterised protein family HicB DC74_RS21230 0ce57e461a043fe06bb4f0f9778c9731 170 Gene3D G3DSA:1.10.1220.10 109 147 9.4E-9 T 23-04-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DC74_RS21230 0ce57e461a043fe06bb4f0f9778c9731 170 SUPERFAMILY SSF47598 107 150 2.45E-10 T 23-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 DC74_RS33910 94142a71d177a89866b01627cc02c168 311 Gene3D G3DSA:3.20.20.330 12 309 4.1E-88 T 23-04-2016 IPR003726 Homocysteine-binding domain DC74_RS33910 94142a71d177a89866b01627cc02c168 311 SUPERFAMILY SSF82282 12 310 4.97E-78 T 23-04-2016 IPR003726 Homocysteine-binding domain DC74_RS33910 94142a71d177a89866b01627cc02c168 311 Pfam PF02574 Homocysteine S-methyltransferase 22 307 6.5E-68 T 23-04-2016 IPR003726 Homocysteine-binding domain DC74_RS33910 94142a71d177a89866b01627cc02c168 311 PANTHER PTHR21091 20 306 2.6E-88 T 23-04-2016 DC74_RS33910 94142a71d177a89866b01627cc02c168 311 PANTHER PTHR21091:SF123 20 306 2.6E-88 T 23-04-2016 DC74_RS38110 29a1edc0c50edcaafa2aeff0ad803c1b 469 SUPERFAMILY SSF103473 16 205 4.32E-49 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS38110 29a1edc0c50edcaafa2aeff0ad803c1b 469 SUPERFAMILY SSF103473 260 457 4.32E-49 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS38110 29a1edc0c50edcaafa2aeff0ad803c1b 469 PANTHER PTHR23501 25 464 4.0E-62 T 23-04-2016 DC74_RS38110 29a1edc0c50edcaafa2aeff0ad803c1b 469 Pfam PF07690 Major Facilitator Superfamily 26 419 5.0E-39 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS38110 29a1edc0c50edcaafa2aeff0ad803c1b 469 Gene3D G3DSA:1.20.1250.20 17 203 2.3E-26 T 23-04-2016 DC74_RS38110 29a1edc0c50edcaafa2aeff0ad803c1b 469 Gene3D G3DSA:1.20.1250.20 277 456 1.9E-9 T 23-04-2016 DC74_RS40620 30909c6df1de1fd84e3023ba7e14e9be 307 Gene3D G3DSA:1.10.510.10 125 300 2.1E-7 T 23-04-2016 DC74_RS40620 30909c6df1de1fd84e3023ba7e14e9be 307 SUPERFAMILY SSF56112 117 300 6.42E-11 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS22715 490db1076b4efa47a56e0c31759ff8d0 288 ProDom PD040376 SCO3349 RV0495C/MT0515 ML2435 MB0506C CGL0407 37 266 2.0E-118 T 23-04-2016 DC74_RS13550 f9dc1c5ebe5b7998e88a5b7e9690200f 304 PANTHER PTHR39082 61 304 1.8E-53 T 23-04-2016 DC74_RS13550 f9dc1c5ebe5b7998e88a5b7e9690200f 304 Pfam PF02591 C4-type zinc ribbon domain 262 296 6.3E-12 T 23-04-2016 IPR003743 C4-type zinc ribbon domain DC74_RS40270 48f7278b310290af1e0d9846976860ab 262 SUPERFAMILY SSF53335 27 212 5.47E-33 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40270 48f7278b310290af1e0d9846976860ab 262 Gene3D G3DSA:3.40.50.150 26 210 2.6E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40270 48f7278b310290af1e0d9846976860ab 262 PANTHER PTHR10108 23 208 4.8E-24 T 23-04-2016 DC74_RS40270 48f7278b310290af1e0d9846976860ab 262 Pfam PF08241 Methyltransferase domain 43 135 1.6E-18 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS28510 54e13a1bf59e4893e8c4b72532208a44 445 SUPERFAMILY SSF52743 36 321 4.58E-74 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS28510 54e13a1bf59e4893e8c4b72532208a44 445 PANTHER PTHR10795 47 321 2.0E-50 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS28510 54e13a1bf59e4893e8c4b72532208a44 445 Pfam PF00082 Subtilase family 53 312 5.4E-40 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS28510 54e13a1bf59e4893e8c4b72532208a44 445 Gene3D G3DSA:3.40.50.200 29 320 3.5E-72 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS28510 54e13a1bf59e4893e8c4b72532208a44 445 PRINTS PR00723 Subtilisin serine protease family (S8) signature 257 273 6.5E-12 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS28510 54e13a1bf59e4893e8c4b72532208a44 445 PRINTS PR00723 Subtilisin serine protease family (S8) signature 53 72 6.5E-12 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS28510 54e13a1bf59e4893e8c4b72532208a44 445 PRINTS PR00723 Subtilisin serine protease family (S8) signature 95 108 6.5E-12 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS28510 54e13a1bf59e4893e8c4b72532208a44 445 PANTHER PTHR10795:SF419 47 321 2.0E-50 T 23-04-2016 DC74_RS15705 89314a24a15dd0d8b274b48b876b3914 295 SUPERFAMILY SSF51569 26 283 8.79E-40 T 23-04-2016 DC74_RS15705 89314a24a15dd0d8b274b48b876b3914 295 Gene3D G3DSA:3.20.20.70 26 287 4.9E-41 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS15755 ee9c9b6f1ad015d8a311c21c5f3a7ac5 141 Pfam PF09335 SNARE associated Golgi protein 12 73 2.3E-8 T 23-04-2016 IPR032816 SNARE associated Golgi protein DC74_RS05870 0ac48a4f57cc06564852c79fa2b2b1bb 483 PANTHER PTHR10362 7 479 3.0E-74 T 23-04-2016 DC74_RS05870 0ac48a4f57cc06564852c79fa2b2b1bb 483 Pfam PF00221 Aromatic amino acid lyase 14 453 2.2E-117 T 23-04-2016 IPR001106 Aromatic amino acid lyase DC74_RS05870 0ac48a4f57cc06564852c79fa2b2b1bb 483 PANTHER PTHR10362:SF7 7 479 3.0E-74 T 23-04-2016 DC74_RS05870 0ac48a4f57cc06564852c79fa2b2b1bb 483 SUPERFAMILY SSF48557 7 480 1.49E-117 T 23-04-2016 IPR008948 L-Aspartase-like GO:0003824 DC74_RS05870 0ac48a4f57cc06564852c79fa2b2b1bb 483 Gene3D G3DSA:1.10.275.10 8 161 1.7E-39 T 23-04-2016 IPR024083 Fumarase/histidase, N-terminal DC74_RS05870 0ac48a4f57cc06564852c79fa2b2b1bb 483 Gene3D G3DSA:1.20.200.10 187 479 8.8E-77 T 23-04-2016 DC74_RS16260 03e6a7a72f08ce14448326f7d62d2c9e 236 PANTHER PTHR40763:SF1 3 234 5.0E-86 T 23-04-2016 DC74_RS16260 03e6a7a72f08ce14448326f7d62d2c9e 236 Pfam PF08044 Domain of unknown function (DUF1707) 9 61 2.7E-22 T 23-04-2016 IPR012551 Protein of unknown function DUF1707 DC74_RS16260 03e6a7a72f08ce14448326f7d62d2c9e 236 PANTHER PTHR40763 3 234 5.0E-86 T 23-04-2016 DC74_RS29025 fdabb102520a697e11a69948888fd4b8 162 Pfam PF07301 Protein of unknown function (DUF1453) 7 149 3.3E-6 T 23-04-2016 IPR009916 Protein of unknown function DUF1453 DC74_RS06465 1b0b9d63bb7e533ed995aa5ab0d86b42 217 PANTHER PTHR35010:SF2 3 212 2.4E-41 T 23-04-2016 DC74_RS06465 1b0b9d63bb7e533ed995aa5ab0d86b42 217 PANTHER PTHR35010 3 212 2.4E-41 T 23-04-2016 DC74_RS08285 5025b1d7de066fddfe706fdecb2fac48 236 Pfam PF06149 Protein of unknown function (DUF969) 1 218 6.2E-85 T 23-04-2016 IPR010374 Protein of unknown function DUF969 DC74_RS08285 5025b1d7de066fddfe706fdecb2fac48 236 PANTHER PTHR41293 1 236 1.5E-93 T 23-04-2016 DC74_RS08285 5025b1d7de066fddfe706fdecb2fac48 236 PANTHER PTHR41293:SF1 1 236 1.5E-93 T 23-04-2016 DC74_RS21280 7d1f0895910744f6c4e3945a6c464d54 534 PANTHER PTHR21021 99 125 7.9E-19 T 23-04-2016 DC74_RS21280 7d1f0895910744f6c4e3945a6c464d54 534 PANTHER PTHR21021:SF19 99 125 7.9E-19 T 23-04-2016 DC74_RS21280 7d1f0895910744f6c4e3945a6c464d54 534 PANTHER PTHR21021:SF19 276 389 7.9E-19 T 23-04-2016 DC74_RS21280 7d1f0895910744f6c4e3945a6c464d54 534 PANTHER PTHR21021 276 389 7.9E-19 T 23-04-2016 DC74_RS21280 7d1f0895910744f6c4e3945a6c464d54 534 Gene3D G3DSA:3.30.450.40 99 284 4.1E-5 T 23-04-2016 IPR029016 GAF domain-like DC74_RS21280 7d1f0895910744f6c4e3945a6c464d54 534 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 324 393 2.5E-9 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS23215 7c233adc70088b1888be56c5b948f54b 246 Pfam PF00072 Response regulator receiver domain 13 123 4.3E-30 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS23215 7c233adc70088b1888be56c5b948f54b 246 SUPERFAMILY SSF46894 142 240 2.44E-30 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS23215 7c233adc70088b1888be56c5b948f54b 246 PANTHER PTHR26402 11 240 3.3E-93 T 23-04-2016 DC74_RS23215 7c233adc70088b1888be56c5b948f54b 246 SUPERFAMILY SSF52172 9 133 1.42E-43 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS23215 7c233adc70088b1888be56c5b948f54b 246 SMART SM00448 11 122 1.2E-42 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS23215 7c233adc70088b1888be56c5b948f54b 246 PANTHER PTHR26402:SF556 11 240 3.3E-93 T 23-04-2016 DC74_RS23215 7c233adc70088b1888be56c5b948f54b 246 SMART SM00862 164 239 2.2E-26 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS23215 7c233adc70088b1888be56c5b948f54b 246 Gene3D G3DSA:3.40.50.2300 9 131 2.2E-41 T 23-04-2016 DC74_RS23215 7c233adc70088b1888be56c5b948f54b 246 Gene3D G3DSA:1.10.10.10 141 240 8.5E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS23215 7c233adc70088b1888be56c5b948f54b 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 165 239 3.1E-26 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS29675 8915873eb3c8f22cc4776bac36b322ed 328 Pfam PF07853 Protein of unknown function (DUF1648) 27 70 1.2E-9 T 23-04-2016 IPR012867 Domain of unknown function DUF1648 DC74_RS16025 0ba75b91234419ea5859414322d78bb1 197 PANTHER PTHR23029:SF23 1 196 3.0E-108 T 23-04-2016 DC74_RS16025 0ba75b91234419ea5859414322d78bb1 197 PANTHER PTHR23029 1 196 3.0E-108 T 23-04-2016 DC74_RS16025 0ba75b91234419ea5859414322d78bb1 197 SUPERFAMILY SSF53254 1 197 2.01E-50 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS16025 0ba75b91234419ea5859414322d78bb1 197 Gene3D G3DSA:3.40.50.1240 1 197 1.4E-49 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS16025 0ba75b91234419ea5859414322d78bb1 197 PIRSF PIRSF000709 1 178 2.5E-12 T 23-04-2016 DC74_RS16025 0ba75b91234419ea5859414322d78bb1 197 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 193 4.2E-51 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS16025 0ba75b91234419ea5859414322d78bb1 197 SMART SM00855 4 153 2.4E-23 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS37160 25611d0e5f5a1eda7a517d477176adf7 470 ProSitePatterns PS00571 Amidases signature. 154 185 - T 23-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS37160 25611d0e5f5a1eda7a517d477176adf7 470 Gene3D G3DSA:3.90.1300.10 3 462 5.5E-128 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS37160 25611d0e5f5a1eda7a517d477176adf7 470 PANTHER PTHR11895 4 467 1.1E-127 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS37160 25611d0e5f5a1eda7a517d477176adf7 470 SUPERFAMILY SSF75304 4 465 1.28E-124 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS37160 25611d0e5f5a1eda7a517d477176adf7 470 Pfam PF01425 Amidase 26 450 5.0E-101 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DC74_RS19860 64e0b4b85b313f5c31f6e870bd80ab39 266 SUPERFAMILY SSF140959 10 265 8.11E-77 T 23-04-2016 DC74_RS19860 64e0b4b85b313f5c31f6e870bd80ab39 266 PANTHER PTHR10138 11 266 4.8E-67 T 23-04-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 DC74_RS19860 64e0b4b85b313f5c31f6e870bd80ab39 266 PANTHER PTHR10138:SF0 11 266 4.8E-67 T 23-04-2016 DC74_RS19860 64e0b4b85b313f5c31f6e870bd80ab39 266 Pfam PF03301 Tryptophan 2,3-dioxygenase 8 193 9.2E-46 T 23-04-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 DC74_RS19860 64e0b4b85b313f5c31f6e870bd80ab39 266 Pfam PF03301 Tryptophan 2,3-dioxygenase 199 266 3.8E-25 T 23-04-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 DC74_RS19860 64e0b4b85b313f5c31f6e870bd80ab39 266 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 4 266 35.578 T 23-04-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|UniPathway: UPA00333 DC74_RS26665 96765386199f7c8197e962278a2c7a24 401 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 3.1E-22 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS26665 96765386199f7c8197e962278a2c7a24 401 PANTHER PTHR33169:SF2 1 130 2.8E-35 T 23-04-2016 DC74_RS26665 96765386199f7c8197e962278a2c7a24 401 Gene3D G3DSA:1.10.10.10 4 97 7.9E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26665 96765386199f7c8197e962278a2c7a24 401 SUPERFAMILY SSF46785 10 109 1.69E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26665 96765386199f7c8197e962278a2c7a24 401 PANTHER PTHR33169 1 130 2.8E-35 T 23-04-2016 DC74_RS13355 034b2a6dc87eb32db252b08f4cec80f6 268 PANTHER PTHR35864 1 259 1.2E-41 T 23-04-2016 DC74_RS36800 74a47c288d75fb7905d1300ea46b1157 194 SUPERFAMILY SSF51182 1 182 1.6E-52 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS36800 74a47c288d75fb7905d1300ea46b1157 194 Pfam PF05962 HutD 10 179 2.4E-56 T 23-04-2016 IPR010282 Uncharacterised protein family HutD/Ves DC74_RS36800 74a47c288d75fb7905d1300ea46b1157 194 Gene3D G3DSA:2.60.120.10 10 106 8.5E-39 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS36800 74a47c288d75fb7905d1300ea46b1157 194 Gene3D G3DSA:2.60.120.10 107 184 4.2E-6 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS36800 74a47c288d75fb7905d1300ea46b1157 194 PANTHER PTHR37943:SF1 1 145 1.3E-43 T 23-04-2016 DC74_RS36800 74a47c288d75fb7905d1300ea46b1157 194 PANTHER PTHR37943 1 145 1.3E-43 T 23-04-2016 DC74_RS37060 444de73013324116c6785d3fe079fcfe 461 Gene3D G3DSA:3.40.640.10 82 337 1.3E-42 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS37060 444de73013324116c6785d3fe079fcfe 461 SUPERFAMILY SSF53383 62 454 7.39E-57 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS37060 444de73013324116c6785d3fe079fcfe 461 Gene3D G3DSA:3.90.1150.10 338 455 3.7E-14 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS37060 444de73013324116c6785d3fe079fcfe 461 Pfam PF00202 Aminotransferase class-III 62 453 1.8E-49 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS37060 444de73013324116c6785d3fe079fcfe 461 PANTHER PTHR11986 62 413 1.1E-42 T 23-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DC74_RS05045 515586e372e54dd7a19a6f6c0caa10d5 310 PANTHER PTHR37285:SF2 37 309 4.4E-72 T 23-04-2016 DC74_RS05045 515586e372e54dd7a19a6f6c0caa10d5 310 Pfam PF05141 Pyoverdine/dityrosine biosynthesis protein 46 293 6.5E-76 T 23-04-2016 IPR007817 Pyoverdine biosynthesis DC74_RS05045 515586e372e54dd7a19a6f6c0caa10d5 310 PIRSF PIRSF037196 13 310 7.0E-98 T 23-04-2016 IPR017133 Pyoverdine chromophore biosynthesis protein PvcA DC74_RS05045 515586e372e54dd7a19a6f6c0caa10d5 310 PANTHER PTHR37285 37 309 4.4E-72 T 23-04-2016 DC74_RS08690 b4e52249272278e71cca4a19b1b16a2a 65 Pfam PF05532 CsbD-like 4 52 5.3E-14 T 23-04-2016 IPR008462 CsbD-like DC74_RS08690 b4e52249272278e71cca4a19b1b16a2a 65 Gene3D G3DSA:1.10.1470.10 4 61 7.6E-15 T 23-04-2016 IPR008462 CsbD-like DC74_RS08690 b4e52249272278e71cca4a19b1b16a2a 65 SUPERFAMILY SSF69047 4 61 1.44E-10 T 23-04-2016 IPR008462 CsbD-like DC74_RS09920 d2c085486a05b3123251e1e1c9d2ee08 153 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 140 2.5E-14 T 23-04-2016 IPR019587 Polyketide cyclase/dehydrase DC74_RS09920 d2c085486a05b3123251e1e1c9d2ee08 153 Gene3D G3DSA:3.30.530.20 3 139 2.7E-10 T 23-04-2016 IPR023393 START-like domain DC74_RS09920 d2c085486a05b3123251e1e1c9d2ee08 153 SUPERFAMILY SSF55961 1 125 5.7E-18 T 23-04-2016 DC74_RS31140 e5b5211990dd19d945eb3ddcbcc61c10 291 SUPERFAMILY SSF53335 118 147 2.22E-6 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS31140 e5b5211990dd19d945eb3ddcbcc61c10 291 SUPERFAMILY SSF53335 37 82 2.22E-6 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS33405 c488d643d994e7cdfee9eb8211246196 317 PANTHER PTHR21581:SF1 40 300 5.7E-62 T 23-04-2016 DC74_RS33405 c488d643d994e7cdfee9eb8211246196 317 Gene3D G3DSA:3.40.710.10 49 300 2.5E-65 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS33405 c488d643d994e7cdfee9eb8211246196 317 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 52 279 9.3E-35 T 23-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 DC74_RS33405 c488d643d994e7cdfee9eb8211246196 317 PANTHER PTHR21581 40 300 5.7E-62 T 23-04-2016 DC74_RS33405 c488d643d994e7cdfee9eb8211246196 317 SUPERFAMILY SSF56601 18 300 3.47E-46 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS14385 3383566a06afec27c3bc2ef3ac613056 245 Pfam PF08241 Methyltransferase domain 93 139 1.2E-7 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS14385 3383566a06afec27c3bc2ef3ac613056 245 SUPERFAMILY SSF53335 90 237 3.04E-16 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14385 3383566a06afec27c3bc2ef3ac613056 245 Gene3D G3DSA:3.40.50.150 91 245 4.3E-17 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS36225 e37de7ee4c37fa486b5fa40b4f3b578f 159 Gene3D G3DSA:1.20.120.450 8 155 7.5E-33 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS36225 e37de7ee4c37fa486b5fa40b4f3b578f 159 Pfam PF04978 Protein of unknown function (DUF664) 15 156 5.6E-43 T 23-04-2016 IPR007061 Protein of unknown function DUF664 DC74_RS36225 e37de7ee4c37fa486b5fa40b4f3b578f 159 SUPERFAMILY SSF109854 8 155 2.29E-36 T 23-04-2016 DC74_RS19390 8e5e7fbc3255982ad237307f7f263e24 446 PANTHER PTHR23242 1 286 1.7E-36 T 23-04-2016 DC74_RS19390 8e5e7fbc3255982ad237307f7f263e24 446 Pfam PF10935 Protein of unknown function (DUF2637) 11 164 6.9E-36 T 23-04-2016 IPR021235 Protein of unknown function DUF2637 DC74_RS00325 b016530d0e47a29fa72604ee86f7297a 317 Pfam PF04909 Amidohydrolase 8 270 1.3E-25 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 DC74_RS00325 b016530d0e47a29fa72604ee86f7297a 317 SUPERFAMILY SSF51556 8 282 7.33E-55 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS00325 b016530d0e47a29fa72604ee86f7297a 317 PANTHER PTHR21240:SF3 8 269 7.1E-51 T 23-04-2016 IPR032465 Amino-carboxymuconate-semialdehyde decarboxylase GO:0001760|GO:0006568|GO:1904984 KEGG: 00380+4.1.1.45|MetaCyc: PWY-5647|MetaCyc: PWY-5652|MetaCyc: PWY-5654|UniPathway: UPA00270 DC74_RS00325 b016530d0e47a29fa72604ee86f7297a 317 PANTHER PTHR21240 8 269 7.1E-51 T 23-04-2016 DC74_RS00325 b016530d0e47a29fa72604ee86f7297a 317 Gene3D G3DSA:3.20.20.140 7 304 1.2E-72 T 23-04-2016 DC74_RS10565 e7403bda4d2594ef43fd905282a2968a 298 SUPERFAMILY SSF103481 41 119 8.5E-6 T 23-04-2016 DC74_RS10565 e7403bda4d2594ef43fd905282a2968a 298 PANTHER PTHR40761:SF1 1 292 2.7E-71 T 23-04-2016 DC74_RS10565 e7403bda4d2594ef43fd905282a2968a 298 PANTHER PTHR40761 1 292 2.7E-71 T 23-04-2016 DC74_RS11420 9278bf28601fc9c2feae60b0d70f3f79 314 Pfam PF02104 SURF1 family 19 230 1.1E-33 T 23-04-2016 IPR002994 Surfeit locus 1/Shy1 GO:0016020 DC74_RS11420 9278bf28601fc9c2feae60b0d70f3f79 314 PANTHER PTHR23427 11 257 1.6E-23 T 23-04-2016 DC74_RS11420 9278bf28601fc9c2feae60b0d70f3f79 314 PANTHER PTHR23427:SF2 11 257 1.6E-23 T 23-04-2016 DC74_RS28720 16cb73cdbf80277f7d9ced7a116b4eeb 102 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 3 98 1.8E-13 T 23-04-2016 IPR008407 Branched-chain amino acid transport, AzlD DC74_RS04320 c008c2dec97bdd9e82b63321231217fd 559 PANTHER PTHR11706 31 266 2.4E-12 T 23-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 DC74_RS04320 c008c2dec97bdd9e82b63321231217fd 559 Pfam PF01566 Natural resistance-associated macrophage protein 84 437 7.9E-78 T 23-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 DC74_RS04320 c008c2dec97bdd9e82b63321231217fd 559 PANTHER PTHR11706:SF43 31 266 2.4E-12 T 23-04-2016 DC74_RS18035 84bf2f302e2c353a08e9874cd4eda645 381 Gene3D G3DSA:3.40.390.10 172 206 8.9E-4 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 DC74_RS18035 84bf2f302e2c353a08e9874cd4eda645 381 PANTHER PTHR41775 8 377 1.8E-64 T 23-04-2016 DC74_RS18035 84bf2f302e2c353a08e9874cd4eda645 381 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 40 306 2.6E-42 T 23-04-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 DC74_RS14730 d0e12204b638732cd6190f7cd47c2685 118 SUPERFAMILY SSF50022 19 115 3.27E-29 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS14730 d0e12204b638732cd6190f7cd47c2685 118 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 19 115 5.6E-26 T 23-04-2016 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 DC74_RS14730 d0e12204b638732cd6190f7cd47c2685 118 PANTHER PTHR40562 12 116 4.5E-34 T 23-04-2016 DC74_RS14730 d0e12204b638732cd6190f7cd47c2685 118 Gene3D G3DSA:2.102.10.10 18 116 6.3E-34 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS14730 d0e12204b638732cd6190f7cd47c2685 118 Pfam PF13806 Rieske-like [2Fe-2S] domain 19 116 5.3E-32 T 23-04-2016 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 DC74_RS12935 d13af3f4afbbeec51514a6f299f9623a 324 PANTHER PTHR10584:SF15 2 309 1.8E-124 T 23-04-2016 DC74_RS12935 d13af3f4afbbeec51514a6f299f9623a 324 SUPERFAMILY SSF53613 2 295 1.25E-51 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS12935 d13af3f4afbbeec51514a6f299f9623a 324 Pfam PF00294 pfkB family carbohydrate kinase 32 295 1.1E-37 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS12935 d13af3f4afbbeec51514a6f299f9623a 324 Gene3D G3DSA:3.40.1190.20 2 308 2.0E-45 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS12935 d13af3f4afbbeec51514a6f299f9623a 324 PANTHER PTHR10584 2 309 1.8E-124 T 23-04-2016 DC74_RS30010 8ec0c699db30c7b4a8bffd78cbf73935 317 Pfam PF01636 Phosphotransferase enzyme family 43 255 2.6E-23 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS30010 8ec0c699db30c7b4a8bffd78cbf73935 317 SUPERFAMILY SSF56112 17 262 5.98E-25 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS30010 8ec0c699db30c7b4a8bffd78cbf73935 317 Gene3D G3DSA:3.90.1200.10 125 262 1.1E-14 T 23-04-2016 DC74_RS26475 65b425d2044cd6370648be45e666b545 85 PANTHER PTHR38839:SF3 1 81 2.3E-39 T 23-04-2016 DC74_RS26475 65b425d2044cd6370648be45e666b545 85 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 78 14.269 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS26475 65b425d2044cd6370648be45e666b545 85 PANTHER PTHR38839 1 81 2.3E-39 T 23-04-2016 DC74_RS26475 65b425d2044cd6370648be45e666b545 85 Pfam PF02467 Transcription factor WhiB 3 71 1.0E-27 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 SUPERFAMILY SSF51735 5 256 2.61E-80 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 PANTHER PTHR24321:SF6 2 256 4.7E-52 T 23-04-2016 DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 PANTHER PTHR24321 2 256 4.7E-52 T 23-04-2016 DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.5E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.5E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.5E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 6.4E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.4E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.4E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.4E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.4E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.4E-44 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 254 7.9E-67 T 23-04-2016 DC74_RS18195 8a76de161297a4033dc040034cc3f06c 261 Gene3D G3DSA:3.40.50.720 1 256 2.5E-84 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27840 b5465f8addecf42dfd85bebf03fe641d 136 Pfam PF05331 Protein of unknown function (DUF742) 24 136 8.8E-40 T 23-04-2016 IPR007995 Protein of unknown function DUF742 DC74_RS27840 b5465f8addecf42dfd85bebf03fe641d 136 PANTHER PTHR36221 2 136 2.8E-42 T 23-04-2016 DC74_RS36110 60264fd96a8cdf5d0c20e9c367f4b89d 240 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 47 201 2.6E-30 T 23-04-2016 IPR013382 CRISPR-associated protein Cse2 DC74_RS36110 60264fd96a8cdf5d0c20e9c367f4b89d 240 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 49 202 2.2E-17 T 23-04-2016 IPR013382 CRISPR-associated protein Cse2 DC74_RS31150 d08f07296e0d20821cb8ec958cff0c5d 555 Pfam PF13556 PucR C-terminal helix-turn-helix domain 496 553 1.2E-21 T 23-04-2016 IPR025736 PucR C-terminal helix-turn-helix domain DC74_RS31150 d08f07296e0d20821cb8ec958cff0c5d 555 Pfam PF07905 Purine catabolism regulatory protein-like family 6 120 1.2E-26 T 23-04-2016 IPR012914 Purine catabolism PurC-like domain DC74_RS31150 d08f07296e0d20821cb8ec958cff0c5d 555 PANTHER PTHR33744:SF3 1 554 1.8E-134 T 23-04-2016 DC74_RS31150 d08f07296e0d20821cb8ec958cff0c5d 555 PANTHER PTHR33744 1 554 1.8E-134 T 23-04-2016 DC74_RS28365 c36ebd19c2cb4b9119b1f7ce13000909 561 Pfam PF07905 Purine catabolism regulatory protein-like family 9 124 2.3E-31 T 23-04-2016 IPR012914 Purine catabolism PurC-like domain DC74_RS28365 c36ebd19c2cb4b9119b1f7ce13000909 561 PANTHER PTHR33744 2 314 6.9E-134 T 23-04-2016 DC74_RS28365 c36ebd19c2cb4b9119b1f7ce13000909 561 PANTHER PTHR33744 334 561 6.9E-134 T 23-04-2016 DC74_RS28365 c36ebd19c2cb4b9119b1f7ce13000909 561 Pfam PF13556 PucR C-terminal helix-turn-helix domain 496 554 5.0E-23 T 23-04-2016 IPR025736 PucR C-terminal helix-turn-helix domain DC74_RS28365 c36ebd19c2cb4b9119b1f7ce13000909 561 PANTHER PTHR33744:SF3 2 314 6.9E-134 T 23-04-2016 DC74_RS28365 c36ebd19c2cb4b9119b1f7ce13000909 561 PANTHER PTHR33744:SF3 334 561 6.9E-134 T 23-04-2016 DC74_RS03735 7f6f45bdc604f121550e2efce61efa4c 389 SUPERFAMILY SSF53756 1 389 3.14E-74 T 23-04-2016 DC74_RS03735 7f6f45bdc604f121550e2efce61efa4c 389 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 223 368 8.9E-17 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS03735 7f6f45bdc604f121550e2efce61efa4c 389 Gene3D G3DSA:3.40.50.2000 222 368 6.7E-31 T 23-04-2016 DC74_RS03735 7f6f45bdc604f121550e2efce61efa4c 389 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 12 389 6.7E-112 T 23-04-2016 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 DC74_RS03735 7f6f45bdc604f121550e2efce61efa4c 389 PANTHER PTHR11926:SF16 1 389 2.4E-45 T 23-04-2016 DC74_RS03735 7f6f45bdc604f121550e2efce61efa4c 389 Gene3D G3DSA:3.40.50.2000 12 221 2.5E-14 T 23-04-2016 DC74_RS03735 7f6f45bdc604f121550e2efce61efa4c 389 PANTHER PTHR11926 1 389 2.4E-45 T 23-04-2016 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 DC74_RS16135 3fb7d48bee06a49457cda4d984c239f1 197 SUPERFAMILY SSF81296 28 196 4.2E-60 T 23-04-2016 IPR014756 Immunoglobulin E-set DC74_RS16135 3fb7d48bee06a49457cda4d984c239f1 197 Gene3D G3DSA:2.70.50.50 28 196 1.5E-62 T 23-04-2016 DC74_RS16135 3fb7d48bee06a49457cda4d984c239f1 197 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 28 194 2.2E-41 T 23-04-2016 IPR004302 Chitin-binding protein, N-terminal DC74_RS16135 3fb7d48bee06a49457cda4d984c239f1 197 PANTHER PTHR34823 1 196 8.0E-73 T 23-04-2016 DC74_RS31795 686c89afffab47c0d2dd52fb067dff2b 187 Gene3D G3DSA:3.40.630.30 2 185 3.1E-43 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31795 686c89afffab47c0d2dd52fb067dff2b 187 PANTHER PTHR23091 99 187 2.1E-14 T 23-04-2016 DC74_RS31795 686c89afffab47c0d2dd52fb067dff2b 187 PANTHER PTHR23091 1 74 2.1E-14 T 23-04-2016 DC74_RS31795 686c89afffab47c0d2dd52fb067dff2b 187 SUPERFAMILY SSF55729 3 186 3.09E-28 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31795 686c89afffab47c0d2dd52fb067dff2b 187 Pfam PF00583 Acetyltransferase (GNAT) family 59 161 1.1E-12 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS22520 9a12cdcafb9979a9a64a69caf8322ca4 339 SUPERFAMILY SSF53335 3 322 2.66E-39 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS22520 9a12cdcafb9979a9a64a69caf8322ca4 339 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 55 260 6.0E-13 T 23-04-2016 IPR003788 Putative S-adenosyl-L-methionine-dependent methyltransferase MidA DC74_RS02605 a4478487aff9b6fd5e860dec05dfc380 263 SUPERFAMILY SSF55729 80 256 3.26E-22 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS02605 a4478487aff9b6fd5e860dec05dfc380 263 Pfam PF00583 Acetyltransferase (GNAT) family 174 248 6.8E-6 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS02605 a4478487aff9b6fd5e860dec05dfc380 263 Gene3D G3DSA:3.40.630.30 122 253 5.3E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS22370 8bf1eb0fd0a5b16e07366a526bd5d139 182 Pfam PF04978 Protein of unknown function (DUF664) 17 166 1.2E-46 T 23-04-2016 IPR007061 Protein of unknown function DUF664 DC74_RS22370 8bf1eb0fd0a5b16e07366a526bd5d139 182 Gene3D G3DSA:1.20.120.450 8 168 1.2E-41 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS22370 8bf1eb0fd0a5b16e07366a526bd5d139 182 SUPERFAMILY SSF109854 7 165 5.65E-38 T 23-04-2016 DC74_RS01720 c219a3ba104a2f6130e6699e18f11c5f 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 3.2E-21 T 23-04-2016 DC74_RS01720 c219a3ba104a2f6130e6699e18f11c5f 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 3.2E-21 T 23-04-2016 DC74_RS01720 c219a3ba104a2f6130e6699e18f11c5f 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 3.2E-21 T 23-04-2016 DC74_RS01720 c219a3ba104a2f6130e6699e18f11c5f 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 3.2E-21 T 23-04-2016 DC74_RS01720 c219a3ba104a2f6130e6699e18f11c5f 404 SUPERFAMILY SSF51905 5 171 5.06E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS01720 c219a3ba104a2f6130e6699e18f11c5f 404 SUPERFAMILY SSF51905 278 366 5.06E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS01720 c219a3ba104a2f6130e6699e18f11c5f 404 PANTHER PTHR13789:SF174 4 371 9.1E-106 T 23-04-2016 DC74_RS01720 c219a3ba104a2f6130e6699e18f11c5f 404 Pfam PF01494 FAD binding domain 7 234 6.4E-12 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS01720 c219a3ba104a2f6130e6699e18f11c5f 404 Pfam PF01494 FAD binding domain 298 333 4.5E-6 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS01720 c219a3ba104a2f6130e6699e18f11c5f 404 Gene3D G3DSA:3.50.50.60 286 356 1.1E-38 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS01720 c219a3ba104a2f6130e6699e18f11c5f 404 Gene3D G3DSA:3.50.50.60 4 176 1.1E-38 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS01720 c219a3ba104a2f6130e6699e18f11c5f 404 PANTHER PTHR13789 4 371 9.1E-106 T 23-04-2016 DC74_RS03045 11ac336ee08acb84fdef7d6a50ada63d 503 Gene3D G3DSA:3.40.1670.10 334 457 5.3E-12 T 23-04-2016 DC74_RS03045 11ac336ee08acb84fdef7d6a50ada63d 503 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 10 438 1.5E-88 T 23-04-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 DC74_RS03045 11ac336ee08acb84fdef7d6a50ada63d 503 PANTHER PTHR30108 1 502 6.7E-147 T 23-04-2016 DC74_RS03045 11ac336ee08acb84fdef7d6a50ada63d 503 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 15 431 1.6E-119 T 23-04-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 DC74_RS03045 11ac336ee08acb84fdef7d6a50ada63d 503 Hamap MF_01983 UbiD-like decarboxylase. 6 495 51.884 T 23-04-2016 IPR032903 UbiD-like decarboxylase/ferulic acid decarboxylase 1 DC74_RS03045 11ac336ee08acb84fdef7d6a50ada63d 503 PANTHER PTHR30108:SF1 1 502 6.7E-147 T 23-04-2016 DC74_RS03045 11ac336ee08acb84fdef7d6a50ada63d 503 SUPERFAMILY SSF50475 9 316 9.42E-91 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS03045 11ac336ee08acb84fdef7d6a50ada63d 503 SUPERFAMILY SSF143968 319 495 9.68E-26 T 23-04-2016 DC74_RS39000 f4bd6be66b6f48a970b30cccb4870184 470 Pfam PF09594 Protein of unknown function (DUF2029) 156 384 7.7E-11 T 23-04-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 DC74_RS20900 cc141785a35ee58bfebc538eaf2c8c5c 150 Gene3D G3DSA:3.40.630.30 1 149 4.7E-45 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS20900 cc141785a35ee58bfebc538eaf2c8c5c 150 PANTHER PTHR23091 1 140 1.3E-22 T 23-04-2016 DC74_RS20900 cc141785a35ee58bfebc538eaf2c8c5c 150 SUPERFAMILY SSF55729 1 143 1.86E-29 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS20900 cc141785a35ee58bfebc538eaf2c8c5c 150 Pfam PF00583 Acetyltransferase (GNAT) family 58 140 3.8E-14 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS26585 018fed6d34b69b590ec9fd9fb4d3db50 149 Gene3D G3DSA:3.30.70.120 32 146 1.3E-39 T 23-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal DC74_RS26585 018fed6d34b69b590ec9fd9fb4d3db50 149 SUPERFAMILY SSF54913 33 131 2.33E-28 T 23-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta DC74_RS26585 018fed6d34b69b590ec9fd9fb4d3db50 149 Pfam PF02641 Uncharacterized ACR, COG1993 36 131 4.3E-33 T 23-04-2016 IPR003793 Domain of unknown function DUF190 DC74_RS26585 018fed6d34b69b590ec9fd9fb4d3db50 149 PANTHER PTHR35983 29 149 6.7E-34 T 23-04-2016 DC74_RS09015 8556e28d2c255cc3c5e025405b9943d6 464 Pfam PF00083 Sugar (and other) transporter 39 447 9.5E-25 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS09015 8556e28d2c255cc3c5e025405b9943d6 464 SUPERFAMILY SSF103473 34 457 6.67E-61 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS09015 8556e28d2c255cc3c5e025405b9943d6 464 PANTHER PTHR23508:SF1 28 452 2.6E-128 T 23-04-2016 DC74_RS09015 8556e28d2c255cc3c5e025405b9943d6 464 PANTHER PTHR23508 28 452 2.6E-128 T 23-04-2016 DC74_RS09015 8556e28d2c255cc3c5e025405b9943d6 464 Gene3D G3DSA:1.20.1250.20 274 452 2.1E-20 T 23-04-2016 DC74_RS09015 8556e28d2c255cc3c5e025405b9943d6 464 Gene3D G3DSA:1.20.1250.20 41 249 1.2E-19 T 23-04-2016 DC74_RS30550 20b727eb3bfae8bd41ed1ea2fbdc1fb7 104 Pfam PF08239 Bacterial SH3 domain 43 94 2.3E-10 T 23-04-2016 IPR003646 SH3-like domain, bacterial-type DC74_RS12620 cb2c3697964ca0e47f1d5f8319691f35 264 Pfam PF00005 ABC transporter 26 187 1.4E-9 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS12620 cb2c3697964ca0e47f1d5f8319691f35 264 SUPERFAMILY SSF52540 20 219 2.32E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12620 cb2c3697964ca0e47f1d5f8319691f35 264 Gene3D G3DSA:3.40.50.300 20 217 8.3E-22 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS01355 0288d01d55cccf204ec5509e7b9c63a4 112 Pfam PF14230 Domain of unknown function (DUF4333) 33 99 4.7E-11 T 23-04-2016 IPR025637 Domain of unknown function DUF4333 DC74_RS33850 e55cbc3bfcc01f103ebd8adbe4f123aa 272 PANTHER PTHR30582 51 251 3.2E-20 T 23-04-2016 DC74_RS33850 e55cbc3bfcc01f103ebd8adbe4f123aa 272 PANTHER PTHR30582:SF2 51 251 3.2E-20 T 23-04-2016 DC74_RS13790 7ac656b81555807db62a12eda2b68b57 96 Pfam PF01471 Putative peptidoglycan binding domain 31 89 2.1E-13 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS13790 7ac656b81555807db62a12eda2b68b57 96 Gene3D G3DSA:1.10.101.10 25 90 1.6E-18 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS13790 7ac656b81555807db62a12eda2b68b57 96 SUPERFAMILY SSF47090 19 89 1.12E-16 T 23-04-2016 IPR002477 Peptidoglycan binding-like DC74_RS36620 832a8ca4183226c5123de6f9f317170e 328 Gene3D G3DSA:3.90.180.10 4 159 6.9E-57 T 23-04-2016 IPR011032 GroES-like DC74_RS36620 832a8ca4183226c5123de6f9f317170e 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 18 125 6.2E-30 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS36620 832a8ca4183226c5123de6f9f317170e 328 SMART SM00829 4 319 0.0084 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS36620 832a8ca4183226c5123de6f9f317170e 328 SUPERFAMILY SSF51735 133 286 1.75E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36620 832a8ca4183226c5123de6f9f317170e 328 SUPERFAMILY SSF50129 4 158 3.65E-49 T 23-04-2016 IPR011032 GroES-like DC74_RS36620 832a8ca4183226c5123de6f9f317170e 328 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 1 320 5.6E-156 T 23-04-2016 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 DC74_RS36620 832a8ca4183226c5123de6f9f317170e 328 Gene3D G3DSA:3.40.50.720 160 249 3.0E-8 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36620 832a8ca4183226c5123de6f9f317170e 328 PANTHER PTHR11695:SF403 6 328 8.7E-145 T 23-04-2016 DC74_RS36620 832a8ca4183226c5123de6f9f317170e 328 PANTHER PTHR11695 6 328 8.7E-145 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS36620 832a8ca4183226c5123de6f9f317170e 328 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 52 66 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 DC74_RS12275 2a5ef2595608f8662a3a1031ed018fc7 243 Pfam PF01988 VIT family 28 235 2.0E-60 T 23-04-2016 IPR008217 Ccc1 family DC74_RS12275 2a5ef2595608f8662a3a1031ed018fc7 243 PANTHER PTHR31851 1 243 1.1E-67 T 23-04-2016 DC74_RS18895 758fb0b6e427436a0eb059fee65920c4 529 Pfam PF00361 Proton-conducting membrane transporter 140 426 4.3E-59 T 23-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 DC74_RS18895 758fb0b6e427436a0eb059fee65920c4 529 PANTHER PTHR22773:SF40 2 527 2.5E-169 T 23-04-2016 DC74_RS18895 758fb0b6e427436a0eb059fee65920c4 529 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 144 163 9.8E-41 T 23-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 DC74_RS18895 758fb0b6e427436a0eb059fee65920c4 529 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 342 361 9.8E-41 T 23-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 DC74_RS18895 758fb0b6e427436a0eb059fee65920c4 529 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 174 198 9.8E-41 T 23-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 DC74_RS18895 758fb0b6e427436a0eb059fee65920c4 529 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 248 272 9.8E-41 T 23-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 DC74_RS18895 758fb0b6e427436a0eb059fee65920c4 529 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 399 425 9.8E-41 T 23-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 DC74_RS18895 758fb0b6e427436a0eb059fee65920c4 529 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 8 525 3.3E-161 T 23-04-2016 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 DC74_RS18895 758fb0b6e427436a0eb059fee65920c4 529 PANTHER PTHR22773 2 527 2.5E-169 T 23-04-2016 DC74_RS21740 c3e3dedd08da4da3733fa2a79f6d9423 248 Pfam PF14016 Protein of unknown function (DUF4232) 117 244 2.1E-21 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS15585 c76ea3e88727324a60c401a71944ca94 144 PANTHER PTHR31793 2 143 1.7E-32 T 23-04-2016 DC74_RS15585 c76ea3e88727324a60c401a71944ca94 144 Gene3D G3DSA:3.10.129.10 3 134 1.7E-46 T 23-04-2016 IPR029069 HotDog domain DC74_RS15585 c76ea3e88727324a60c401a71944ca94 144 SUPERFAMILY SSF54637 3 132 6.4E-33 T 23-04-2016 IPR029069 HotDog domain DC74_RS15585 c76ea3e88727324a60c401a71944ca94 144 Pfam PF03061 Thioesterase superfamily 17 99 4.5E-17 T 23-04-2016 IPR006683 Thioesterase domain DC74_RS39270 5ee8b26e1b30c3717cae33ae3396ceb1 310 Pfam PF03781 Sulfatase-modifying factor enzyme 1 95 305 9.4E-48 T 23-04-2016 IPR005532 Sulfatase-modifying factor enzyme DC74_RS39270 5ee8b26e1b30c3717cae33ae3396ceb1 310 Gene3D G3DSA:3.90.1580.10 60 307 4.7E-54 T 23-04-2016 IPR005532 Sulfatase-modifying factor enzyme DC74_RS39270 5ee8b26e1b30c3717cae33ae3396ceb1 310 SUPERFAMILY SSF56436 63 307 4.94E-56 T 23-04-2016 IPR016187 C-type lectin fold DC74_RS39270 5ee8b26e1b30c3717cae33ae3396ceb1 310 PANTHER PTHR23150 103 308 1.7E-56 T 23-04-2016 DC74_RS38340 ae5b7de5b19c464b9754fd11fc6fdf8a 161 Pfam PF08974 Domain of unknown function (DUF1877) 1 154 4.1E-28 T 23-04-2016 IPR015068 Protein of unknown function DUF1877 DC74_RS38340 ae5b7de5b19c464b9754fd11fc6fdf8a 161 Gene3D G3DSA:3.40.1760.10 1 158 1.2E-15 T 23-04-2016 IPR015068 Protein of unknown function DUF1877 DC74_RS38340 ae5b7de5b19c464b9754fd11fc6fdf8a 161 SUPERFAMILY SSF111069 44 159 5.49E-13 T 23-04-2016 IPR015068 Protein of unknown function DUF1877 DC74_RS25765 1bd86e841bfa33630508100b85dacea2 153 Pfam PF13581 Histidine kinase-like ATPase domain 36 146 6.4E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS25765 1bd86e841bfa33630508100b85dacea2 153 SUPERFAMILY SSF55874 58 149 8.78E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS07490 68082c062c25a5fb30dfa25211246e07 416 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 249 8.3E-32 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal DC74_RS07490 68082c062c25a5fb30dfa25211246e07 416 SMART SM00825 Beta-ketoacyl synthase 9 411 0.0089 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain DC74_RS07490 68082c062c25a5fb30dfa25211246e07 416 SUPERFAMILY SSF53901 10 254 1.63E-50 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS07490 68082c062c25a5fb30dfa25211246e07 416 Gene3D G3DSA:3.40.47.10 274 412 5.4E-33 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS07490 68082c062c25a5fb30dfa25211246e07 416 PANTHER PTHR11712 10 410 1.6E-65 T 23-04-2016 DC74_RS07490 68082c062c25a5fb30dfa25211246e07 416 SUPERFAMILY SSF53901 218 411 1.68E-44 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS07490 68082c062c25a5fb30dfa25211246e07 416 Gene3D G3DSA:3.40.47.10 10 263 1.6E-45 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS07490 68082c062c25a5fb30dfa25211246e07 416 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 370 1.0E-21 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal DC74_RS30530 184dac9b171fa540b999fd7da86efb9f 186 Pfam PF16259 Domain of unknown function (DUF4913) 65 161 4.5E-26 T 23-04-2016 IPR032584 Protein of unknown function DUF4913 DC74_RS35265 2259010945c1571c0823a431d2462520 140 Gene3D G3DSA:3.10.180.10 14 129 3.3E-12 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS35265 2259010945c1571c0823a431d2462520 140 SUPERFAMILY SSF54593 11 129 5.36E-15 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS22955 ff7218c2a83cab62ac5ecb6aa8083421 330 Gene3D G3DSA:1.10.3720.10 42 325 5.6E-35 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS22955 ff7218c2a83cab62ac5ecb6aa8083421 330 SUPERFAMILY SSF161098 43 314 6.41E-33 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS22955 ff7218c2a83cab62ac5ecb6aa8083421 330 PANTHER PTHR30425 26 329 3.9E-133 T 23-04-2016 DC74_RS22955 ff7218c2a83cab62ac5ecb6aa8083421 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 321 4.7E-14 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS22955 ff7218c2a83cab62ac5ecb6aa8083421 330 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 30 322 4.4E-87 T 23-04-2016 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 DC74_RS22955 ff7218c2a83cab62ac5ecb6aa8083421 330 PANTHER PTHR30425:SF1 26 329 3.9E-133 T 23-04-2016 DC74_RS21275 eeaf13e08583f8b8eae37c78661424d4 489 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 396 408 - T 23-04-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site DC74_RS21275 eeaf13e08583f8b8eae37c78661424d4 489 PANTHER PTHR10804:SF17 47 484 5.0E-109 T 23-04-2016 DC74_RS21275 eeaf13e08583f8b8eae37c78661424d4 489 SUPERFAMILY SSF53092 51 220 3.14E-26 T 23-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal DC74_RS21275 eeaf13e08583f8b8eae37c78661424d4 489 SUPERFAMILY SSF55920 221 483 8.9E-67 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS21275 eeaf13e08583f8b8eae37c78661424d4 489 PANTHER PTHR10804 47 484 5.0E-109 T 23-04-2016 DC74_RS21275 eeaf13e08583f8b8eae37c78661424d4 489 Pfam PF05195 Aminopeptidase P, N-terminal domain 58 179 2.0E-18 T 23-04-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 DC74_RS21275 eeaf13e08583f8b8eae37c78661424d4 489 Gene3D G3DSA:3.40.350.10 53 224 5.8E-35 T 23-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal DC74_RS21275 eeaf13e08583f8b8eae37c78661424d4 489 Gene3D G3DSA:3.90.230.10 225 483 8.4E-68 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS21275 eeaf13e08583f8b8eae37c78661424d4 489 Pfam PF00557 Metallopeptidase family M24 228 462 1.0E-48 T 23-04-2016 IPR000994 Peptidase M24, structural domain DC74_RS21275 eeaf13e08583f8b8eae37c78661424d4 489 SMART SM01011 51 194 7.5E-39 T 23-04-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 1.7E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 1.7E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 1.7E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.9E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.9E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 1.9E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.9E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.9E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 1.9E-46 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 SUPERFAMILY SSF51735 3 230 7.45E-86 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 9.8E-66 T 23-04-2016 DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 Gene3D G3DSA:3.40.50.720 4 232 7.1E-86 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 PANTHER PTHR24322 7 124 8.1E-56 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 PANTHER PTHR24322 140 172 8.1E-56 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 3.5E-9 T 23-04-2016 DC74_RS11320 8154e316c6fa61095848a1a8061843bb 234 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 5 230 4.0E-95 T 23-04-2016 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 DC74_RS27015 e5ce20ff3c2f53a8b54755a4f0cf9f3b 440 PANTHER PTHR11712:SF288 166 425 1.7E-56 T 23-04-2016 DC74_RS27015 e5ce20ff3c2f53a8b54755a4f0cf9f3b 440 SUPERFAMILY SSF53335 162 386 1.0E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS27015 e5ce20ff3c2f53a8b54755a4f0cf9f3b 440 Pfam PF08242 Methyltransferase domain 229 331 1.2E-15 T 23-04-2016 IPR013217 Methyltransferase type 12 DC74_RS27015 e5ce20ff3c2f53a8b54755a4f0cf9f3b 440 Gene3D G3DSA:3.40.50.150 189 385 3.7E-33 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS27015 e5ce20ff3c2f53a8b54755a4f0cf9f3b 440 PANTHER PTHR11712 166 425 1.7E-56 T 23-04-2016 DC74_RS40165 3d0fb2e1583591c05deb8b5688590f0a 583 Gene3D G3DSA:2.60.40.10 60 104 8.1E-4 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS19500 0dcca7e4ea3cde8f37c09770d198a7e0 418 Gene3D G3DSA:1.20.1250.20 17 181 5.2E-7 T 23-04-2016 DC74_RS19500 0dcca7e4ea3cde8f37c09770d198a7e0 418 PANTHER PTHR23514:SF13 9 418 7.2E-133 T 23-04-2016 DC74_RS19500 0dcca7e4ea3cde8f37c09770d198a7e0 418 Gene3D G3DSA:1.20.1250.20 213 389 3.3E-19 T 23-04-2016 DC74_RS19500 0dcca7e4ea3cde8f37c09770d198a7e0 418 Pfam PF07690 Major Facilitator Superfamily 219 392 2.3E-12 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS19500 0dcca7e4ea3cde8f37c09770d198a7e0 418 SUPERFAMILY SSF103473 15 393 1.44E-35 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS19500 0dcca7e4ea3cde8f37c09770d198a7e0 418 PANTHER PTHR23514 9 418 7.2E-133 T 23-04-2016 DC74_RS17965 7d74d5da19c79d6524bedaae55b348e0 441 PANTHER PTHR30582:SF2 27 441 3.4E-115 T 23-04-2016 DC74_RS17965 7d74d5da19c79d6524bedaae55b348e0 441 Pfam PF03734 L,D-transpeptidase catalytic domain 283 411 4.5E-15 T 23-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 DC74_RS17965 7d74d5da19c79d6524bedaae55b348e0 441 Gene3D G3DSA:2.40.440.10 285 412 6.2E-19 T 23-04-2016 DC74_RS17965 7d74d5da19c79d6524bedaae55b348e0 441 PANTHER PTHR30582 27 441 3.4E-115 T 23-04-2016 DC74_RS17965 7d74d5da19c79d6524bedaae55b348e0 441 SUPERFAMILY SSF141523 285 411 1.06E-24 T 23-04-2016 DC74_RS00880 0a0fb6934e9975365ef533744aa35e65 249 PANTHER PTHR26402 160 248 1.4E-82 T 23-04-2016 DC74_RS00880 0a0fb6934e9975365ef533744aa35e65 249 PANTHER PTHR26402 14 144 1.4E-82 T 23-04-2016 DC74_RS00880 0a0fb6934e9975365ef533744aa35e65 249 Gene3D G3DSA:1.10.10.10 153 248 8.7E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00880 0a0fb6934e9975365ef533744aa35e65 249 SMART SM00448 14 124 2.1E-41 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS00880 0a0fb6934e9975365ef533744aa35e65 249 Gene3D G3DSA:3.40.50.2300 14 136 1.7E-39 T 23-04-2016 DC74_RS00880 0a0fb6934e9975365ef533744aa35e65 249 SUPERFAMILY SSF52172 11 132 4.41E-40 T 23-04-2016 IPR011006 CheY-like superfamily DC74_RS00880 0a0fb6934e9975365ef533744aa35e65 249 Pfam PF00072 Response regulator receiver domain 16 125 8.3E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 DC74_RS00880 0a0fb6934e9975365ef533744aa35e65 249 SUPERFAMILY SSF46894 154 247 1.79E-26 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 DC74_RS00880 0a0fb6934e9975365ef533744aa35e65 249 Pfam PF00486 Transcriptional regulatory protein, C terminal 177 247 8.6E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS00880 0a0fb6934e9975365ef533744aa35e65 249 PANTHER PTHR26402:SF50 160 248 1.4E-82 T 23-04-2016 DC74_RS00880 0a0fb6934e9975365ef533744aa35e65 249 PANTHER PTHR26402:SF50 14 144 1.4E-82 T 23-04-2016 DC74_RS00880 0a0fb6934e9975365ef533744aa35e65 249 SMART SM00862 176 247 7.6E-22 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 DC74_RS31370 aaa7c7c534a97f53ec9f2ce404886c83 287 Gene3D G3DSA:1.20.141.10 162 287 5.0E-69 T 23-04-2016 DC74_RS31370 aaa7c7c534a97f53ec9f2ce404886c83 287 PIRSF PIRSF036551 2 287 3.4E-117 T 23-04-2016 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 DC74_RS31370 aaa7c7c534a97f53ec9f2ce404886c83 287 Pfam PF01374 Glycosyl hydrolase family 46 66 275 6.4E-104 T 23-04-2016 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 DC74_RS31370 aaa7c7c534a97f53ec9f2ce404886c83 287 ProSitePatterns PS60000 Chitosanases families 46 and 80 active sites signature. 72 107 - T 23-04-2016 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 DC74_RS31370 aaa7c7c534a97f53ec9f2ce404886c83 287 SUPERFAMILY SSF53955 52 286 7.59E-96 T 23-04-2016 IPR023346 Lysozyme-like domain DC74_RS31370 aaa7c7c534a97f53ec9f2ce404886c83 287 Gene3D G3DSA:3.30.386.10 43 161 5.5E-58 T 23-04-2016 IPR023099 Glycoside hydrolase, family 46, N-terminal GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 DC74_RS12095 985acf324505cf5f22975af3d8142e10 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 293 1.0E-49 T 23-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 DC74_RS12095 985acf324505cf5f22975af3d8142e10 309 PANTHER PTHR11795:SF371 3 308 3.3E-115 T 23-04-2016 DC74_RS12095 985acf324505cf5f22975af3d8142e10 309 PANTHER PTHR11795 3 308 3.3E-115 T 23-04-2016 DC74_RS00905 180353d074aeec8e66c1592027228b9b 130 SUPERFAMILY SSF51679 2 127 3.03E-14 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS00905 180353d074aeec8e66c1592027228b9b 130 Gene3D G3DSA:3.20.20.30 1 127 1.1E-14 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS00905 180353d074aeec8e66c1592027228b9b 130 Pfam PF00296 Luciferase-like monooxygenase 2 75 6.5E-7 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS07920 b033af9e51fde38d842ac3c92dd10602 218 SUPERFAMILY SSF53335 25 147 2.76E-27 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS07920 b033af9e51fde38d842ac3c92dd10602 218 Gene3D G3DSA:3.40.50.150 25 142 2.5E-25 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS07920 b033af9e51fde38d842ac3c92dd10602 218 PANTHER PTHR10108 7 142 6.1E-18 T 23-04-2016 DC74_RS07920 b033af9e51fde38d842ac3c92dd10602 218 PANTHER PTHR10108:SF705 7 142 6.1E-18 T 23-04-2016 DC74_RS07920 b033af9e51fde38d842ac3c92dd10602 218 Pfam PF08241 Methyltransferase domain 43 135 4.3E-16 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 PRINTS PR00359 B-class P450 signature 204 226 2.1E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 PRINTS PR00359 B-class P450 signature 360 371 2.1E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 PRINTS PR00359 B-class P450 signature 147 163 2.1E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 PRINTS PR00359 B-class P450 signature 164 179 2.1E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 PRINTS PR00359 B-class P450 signature 351 360 2.1E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 PRINTS PR00359 B-class P450 signature 302 329 2.1E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 PRINTS PR00359 B-class P450 signature 330 345 2.1E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 PRINTS PR00359 B-class P450 signature 285 296 2.1E-43 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 Pfam PF00067 Cytochrome P450 285 376 2.0E-12 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 Gene3D G3DSA:1.10.630.10 15 411 5.5E-102 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 PANTHER PTHR24286:SF42 57 416 2.6E-75 T 23-04-2016 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 PANTHER PTHR24286 57 416 2.6E-75 T 23-04-2016 DC74_RS29470 f50cfad0f75932ce819f3d66bc7d431b 416 SUPERFAMILY SSF48264 24 410 3.8E-82 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS32160 c7bfd206b2513524979742840086456a 387 SUPERFAMILY SSF56112 62 274 1.09E-17 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS32160 c7bfd206b2513524979742840086456a 387 Pfam PF01636 Phosphotransferase enzyme family 89 266 5.0E-8 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS32160 c7bfd206b2513524979742840086456a 387 Gene3D G3DSA:3.90.1200.10 145 330 1.3E-7 T 23-04-2016 DC74_RS14675 19fbdf7b77f982d4ff40f62c91f26ada 136 PANTHER PTHR36437 1 136 9.3E-25 T 23-04-2016 DC74_RS14675 19fbdf7b77f982d4ff40f62c91f26ada 136 Gene3D G3DSA:3.10.180.10 14 134 2.8E-21 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS14675 19fbdf7b77f982d4ff40f62c91f26ada 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 131 1.2E-11 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS14675 19fbdf7b77f982d4ff40f62c91f26ada 136 SUPERFAMILY SSF54593 9 134 2.28E-21 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS14290 21a02fbc2c99c5d0489801b9e747c59b 374 Pfam PF12705 PD-(D/E)XK nuclease superfamily 85 244 6.2E-5 T 23-04-2016 DC74_RS00430 c7da9d41142c89c5708eb022f83438be 330 Gene3D G3DSA:3.40.50.300 115 292 2.7E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00430 c7da9d41142c89c5708eb022f83438be 330 Gene3D G3DSA:3.40.50.300 2 27 2.7E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00430 c7da9d41142c89c5708eb022f83438be 330 SUPERFAMILY SSF52540 2 21 3.64E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00430 c7da9d41142c89c5708eb022f83438be 330 SUPERFAMILY SSF52540 129 179 3.64E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00430 c7da9d41142c89c5708eb022f83438be 330 SUPERFAMILY SSF52540 223 289 3.64E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09335 ca99639d26bdcbb61666820ce0965cce 156 Pfam PF00545 ribonuclease 74 152 3.0E-29 T 23-04-2016 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 DC74_RS09335 ca99639d26bdcbb61666820ce0965cce 156 Gene3D G3DSA:3.10.450.30 66 154 2.7E-39 T 23-04-2016 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 DC74_RS09335 ca99639d26bdcbb61666820ce0965cce 156 SUPERFAMILY SSF53933 65 154 1.33E-35 T 23-04-2016 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 DC74_RS05675 a7550709152cba0942b6b73629db9e8e 229 Pfam PF13671 AAA domain 47 179 4.8E-7 T 23-04-2016 DC74_RS05675 a7550709152cba0942b6b73629db9e8e 229 Gene3D G3DSA:3.40.50.300 47 172 9.0E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05675 a7550709152cba0942b6b73629db9e8e 229 SUPERFAMILY SSF52540 40 175 1.34E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS27675 8c39d9ffdb0688afce076da446eb4ec6 330 SUPERFAMILY SSF51735 106 286 1.05E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27675 8c39d9ffdb0688afce076da446eb4ec6 330 PANTHER PTHR10996 1 316 3.6E-137 T 23-04-2016 DC74_RS27675 8c39d9ffdb0688afce076da446eb4ec6 330 Gene3D G3DSA:3.40.50.720 70 121 4.9E-5 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27675 8c39d9ffdb0688afce076da446eb4ec6 330 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 23-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site DC74_RS27675 8c39d9ffdb0688afce076da446eb4ec6 330 Gene3D G3DSA:3.40.50.720 122 286 1.3E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS27675 8c39d9ffdb0688afce076da446eb4ec6 330 PANTHER PTHR10996:SF160 1 316 3.6E-137 T 23-04-2016 DC74_RS27675 8c39d9ffdb0688afce076da446eb4ec6 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 285 4.0E-46 T 23-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DC74_RS08365 18c14e816fa98b30eb56336b0a5b9a01 201 Pfam PF07336 Putative stress-induced transcription regulator 5 151 6.1E-17 T 23-04-2016 IPR010852 Putative stress-induced transcription regulator DC74_RS08365 18c14e816fa98b30eb56336b0a5b9a01 201 PANTHER PTHR35525:SF3 2 201 4.3E-32 T 23-04-2016 DC74_RS08365 18c14e816fa98b30eb56336b0a5b9a01 201 Gene3D G3DSA:1.10.3300.10 3 196 1.2E-39 T 23-04-2016 IPR023286 ABATE domain DC74_RS08365 18c14e816fa98b30eb56336b0a5b9a01 201 SUPERFAMILY SSF160904 3 194 1.31E-38 T 23-04-2016 DC74_RS08365 18c14e816fa98b30eb56336b0a5b9a01 201 PANTHER PTHR35525 2 201 4.3E-32 T 23-04-2016 DC74_RS08365 18c14e816fa98b30eb56336b0a5b9a01 201 Pfam PF11706 CGNR zinc finger 155 195 5.0E-11 T 23-04-2016 IPR021005 Zinc finger, CGNR DC74_RS35345 2b149f81f8b2f34b263c5b905962ab43 492 Gene3D G3DSA:3.40.309.10 273 451 1.7E-62 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 DC74_RS35345 2b149f81f8b2f34b263c5b905962ab43 492 Gene3D G3DSA:3.40.605.10 16 272 1.3E-86 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 DC74_RS35345 2b149f81f8b2f34b263c5b905962ab43 492 PANTHER PTHR11699 14 483 1.3E-183 T 23-04-2016 DC74_RS35345 2b149f81f8b2f34b263c5b905962ab43 492 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 DC74_RS35345 2b149f81f8b2f34b263c5b905962ab43 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 23-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 DC74_RS35345 2b149f81f8b2f34b263c5b905962ab43 492 SUPERFAMILY SSF53720 11 491 4.71E-147 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 DC74_RS35345 2b149f81f8b2f34b263c5b905962ab43 492 Pfam PF00171 Aldehyde dehydrogenase family 23 486 1.2E-149 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 DC74_RS35825 7c894939d3b95f418a82f0d8aedb0d24 233 SUPERFAMILY SSF46689 3 65 1.33E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS35825 7c894939d3b95f418a82f0d8aedb0d24 233 PANTHER PTHR30328:SF29 1 176 6.5E-37 T 23-04-2016 DC74_RS35825 7c894939d3b95f418a82f0d8aedb0d24 233 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 23-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site DC74_RS35825 7c894939d3b95f418a82f0d8aedb0d24 233 SUPERFAMILY SSF48498 77 202 1.86E-21 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS35825 7c894939d3b95f418a82f0d8aedb0d24 233 Gene3D G3DSA:1.10.357.10 3 187 4.8E-34 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS35825 7c894939d3b95f418a82f0d8aedb0d24 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 8.0E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS35825 7c894939d3b95f418a82f0d8aedb0d24 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 8.0E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS35825 7c894939d3b95f418a82f0d8aedb0d24 233 PANTHER PTHR30328 1 176 6.5E-37 T 23-04-2016 DC74_RS35825 7c894939d3b95f418a82f0d8aedb0d24 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 3.5E-18 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS31365 12cd65445270911aba2849247a6b50f2 487 Pfam PF00860 Permease family 25 408 2.6E-95 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS31365 12cd65445270911aba2849247a6b50f2 487 PANTHER PTHR11119 7 440 4.9E-113 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS31365 12cd65445270911aba2849247a6b50f2 487 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 22 438 9.1E-111 T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 DC74_RS31365 12cd65445270911aba2849247a6b50f2 487 TIGRFAM TIGR03173 pbuX: xanthine permease 30 440 4.9E-155 T 23-04-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 DC74_RS31365 12cd65445270911aba2849247a6b50f2 487 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 355 375 - T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 DC74_RS28520 cafbe342d5945c5bff0a865223d10372 110 Gene3D G3DSA:1.10.287.1060 5 105 1.7E-4 T 23-04-2016 DC74_RS25610 1139839b73dfde5d734e4c6d79cbd3d9 119 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 16 105 15.469 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS25610 1139839b73dfde5d734e4c6d79cbd3d9 119 PANTHER PTHR38839 1 115 1.3E-20 T 23-04-2016 DC74_RS25610 1139839b73dfde5d734e4c6d79cbd3d9 119 Pfam PF02467 Transcription factor WhiB 28 96 2.0E-21 T 23-04-2016 IPR003482 Transcription factor WhiB DC74_RS27995 bdf08cc1a21a13fafd22a882f322d317 367 Gene3D G3DSA:1.20.5.620 60 115 4.0E-5 T 23-04-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain DC74_RS05145 1214da6f08a34a88be09b7642455dda8 382 Gene3D G3DSA:3.40.190.10 220 310 2.7E-7 T 23-04-2016 DC74_RS27670 bb231d869ee1448666532337f886b50a 346 Pfam PF00248 Aldo/keto reductase family 16 158 2.0E-36 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS27670 bb231d869ee1448666532337f886b50a 346 Pfam PF00248 Aldo/keto reductase family 189 337 3.9E-20 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS27670 bb231d869ee1448666532337f886b50a 346 Gene3D G3DSA:3.20.20.100 2 159 5.5E-108 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS27670 bb231d869ee1448666532337f886b50a 346 Gene3D G3DSA:3.20.20.100 191 338 5.5E-108 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS27670 bb231d869ee1448666532337f886b50a 346 PANTHER PTHR11732 186 340 2.2E-108 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS27670 bb231d869ee1448666532337f886b50a 346 PANTHER PTHR11732 1 154 2.2E-108 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS27670 bb231d869ee1448666532337f886b50a 346 SUPERFAMILY SSF51430 187 338 5.63E-34 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS27670 bb231d869ee1448666532337f886b50a 346 SUPERFAMILY SSF51430 3 159 7.6E-50 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS16535 ba2eb1ac1ef64b29262b7f794530aba7 598 Pfam PF04851 Type III restriction enzyme, res subunit 28 179 9.9E-14 T 23-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 DC74_RS16535 ba2eb1ac1ef64b29262b7f794530aba7 598 Gene3D G3DSA:3.40.50.300 290 403 1.6E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16535 ba2eb1ac1ef64b29262b7f794530aba7 598 SMART SM00487 25 201 3.9E-17 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain DC74_RS16535 ba2eb1ac1ef64b29262b7f794530aba7 598 SUPERFAMILY SSF52540 141 213 8.27E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16535 ba2eb1ac1ef64b29262b7f794530aba7 598 SUPERFAMILY SSF52540 268 391 8.27E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16535 ba2eb1ac1ef64b29262b7f794530aba7 598 SUPERFAMILY SSF52540 23 183 8.05E-26 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16535 ba2eb1ac1ef64b29262b7f794530aba7 598 Gene3D G3DSA:3.40.50.300 27 182 2.7E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25105 addb1dd08e1626c272c81b2e64296e69 203 Gene3D G3DSA:3.90.950.10 8 196 2.2E-61 T 23-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like DC74_RS25105 addb1dd08e1626c272c81b2e64296e69 203 Pfam PF02545 Maf-like protein 9 193 1.3E-46 T 23-04-2016 IPR003697 Maf-like protein GO:0005737 DC74_RS25105 addb1dd08e1626c272c81b2e64296e69 203 Hamap MF_00528 Septum formation protein Maf [maf]. 9 198 28.748 T 23-04-2016 IPR003697 Maf-like protein GO:0005737 DC74_RS25105 addb1dd08e1626c272c81b2e64296e69 203 SUPERFAMILY SSF52972 8 193 9.16E-54 T 23-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like DC74_RS25105 addb1dd08e1626c272c81b2e64296e69 203 TIGRFAM TIGR00172 maf: septum formation protein Maf 8 191 1.9E-46 T 23-04-2016 IPR003697 Maf-like protein GO:0005737 DC74_RS25105 addb1dd08e1626c272c81b2e64296e69 203 PIRSF PIRSF006305 1 200 1.6E-43 T 23-04-2016 IPR003697 Maf-like protein GO:0005737 DC74_RS24775 e234d9b5b217543e76ced7fb9a7a14d5 43 SUPERFAMILY SSF46955 15 41 1.65E-9 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS24775 e234d9b5b217543e76ced7fb9a7a14d5 43 Pfam PF00376 MerR family regulatory protein 16 41 1.6E-10 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS24775 e234d9b5b217543e76ced7fb9a7a14d5 43 ProSitePatterns PS00552 MerR-type HTH domain signature. 18 40 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS24775 e234d9b5b217543e76ced7fb9a7a14d5 43 Gene3D G3DSA:1.10.1660.10 14 41 7.2E-10 T 23-04-2016 DC74_RS24775 e234d9b5b217543e76ced7fb9a7a14d5 43 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 27 1.3E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS24775 e234d9b5b217543e76ced7fb9a7a14d5 43 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 27 40 1.3E-5 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS28945 c9d8ce4fe3b7d2d8de63eae0b2a1efea 173 PANTHER PTHR32097 5 161 5.6E-36 T 23-04-2016 DC74_RS28945 c9d8ce4fe3b7d2d8de63eae0b2a1efea 173 Pfam PF02342 TerD domain 5 162 3.0E-22 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS28945 c9d8ce4fe3b7d2d8de63eae0b2a1efea 173 Gene3D G3DSA:2.60.60.30 6 166 1.1E-42 T 23-04-2016 DC74_RS19490 180dca98b30de97849f7198cf904122d 270 Pfam PF15698 Phosphatase 7 269 8.9E-109 T 23-04-2016 IPR031423 Uncharacterised phosphatase SCO2771 KEGG: 00051+3.1.3.-|KEGG: 00332+3.1.3.-|KEGG: 00565+3.1.3.-|KEGG: 00600+3.1.3.-|KEGG: 00730+3.1.3.-|KEGG: 00740+3.1.3.-|KEGG: 00760+3.1.3.- DC74_RS01670 a2b6528c206ba0524389b150adba7c79 302 SUPERFAMILY SSF53335 18 298 6.89E-64 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS01670 a2b6528c206ba0524389b150adba7c79 302 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 20 279 2.4E-74 T 23-04-2016 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS01670 a2b6528c206ba0524389b150adba7c79 302 PANTHER PTHR13600 73 285 3.8E-60 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS01670 a2b6528c206ba0524389b150adba7c79 302 PANTHER PTHR13600 14 49 3.8E-60 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS01670 a2b6528c206ba0524389b150adba7c79 302 PANTHER PTHR13600:SF12 73 285 3.8E-60 T 23-04-2016 DC74_RS01670 a2b6528c206ba0524389b150adba7c79 302 PANTHER PTHR13600:SF12 14 49 3.8E-60 T 23-04-2016 DC74_RS01670 a2b6528c206ba0524389b150adba7c79 302 Pfam PF04072 Leucine carboxyl methyltransferase 22 202 2.9E-50 T 23-04-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS01670 a2b6528c206ba0524389b150adba7c79 302 Gene3D G3DSA:3.40.50.150 78 218 9.1E-18 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS31090 529d1a65f0355aab3f0b45dfcd5d5a20 145 SUPERFAMILY SSF46955 1 114 6.23E-24 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS31090 529d1a65f0355aab3f0b45dfcd5d5a20 145 Gene3D G3DSA:1.10.1660.10 1 114 7.0E-27 T 23-04-2016 DC74_RS31090 529d1a65f0355aab3f0b45dfcd5d5a20 145 PANTHER PTHR30204:SF4 1 134 1.9E-38 T 23-04-2016 DC74_RS31090 529d1a65f0355aab3f0b45dfcd5d5a20 145 Pfam PF13411 MerR HTH family regulatory protein 1 67 2.1E-17 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS31090 529d1a65f0355aab3f0b45dfcd5d5a20 145 PANTHER PTHR30204 1 134 1.9E-38 T 23-04-2016 DC74_RS31090 529d1a65f0355aab3f0b45dfcd5d5a20 145 SMART SM00422 1 69 2.8E-20 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 DC74_RS17190 47988b5b71a651a54eb9262f68006913 243 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 205 239 4.5E-5 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain DC74_RS21655 05ac91208ba958ae58a295ae16e55dec 553 Pfam PF05598 Transposase domain (DUF772) 51 114 1.7E-17 T 23-04-2016 IPR008490 Transposase InsH, N-terminal DC74_RS21655 05ac91208ba958ae58a295ae16e55dec 553 Pfam PF13751 Transposase DDE domain 398 522 7.1E-27 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS09395 05ac91208ba958ae58a295ae16e55dec 553 Pfam PF05598 Transposase domain (DUF772) 51 114 1.7E-17 T 23-04-2016 IPR008490 Transposase InsH, N-terminal DC74_RS09395 05ac91208ba958ae58a295ae16e55dec 553 Pfam PF13751 Transposase DDE domain 398 522 7.1E-27 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS37145 578a18c573513120e0b56f08c119a4a8 214 Pfam PF08281 Sigma-70, region 4 131 181 4.3E-10 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37145 578a18c573513120e0b56f08c119a4a8 214 Gene3D G3DSA:1.10.10.10 125 185 5.9E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37145 578a18c573513120e0b56f08c119a4a8 214 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 183 2.5E-24 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37145 578a18c573513120e0b56f08c119a4a8 214 Gene3D G3DSA:1.10.1740.10 11 124 2.6E-24 T 23-04-2016 DC74_RS37145 578a18c573513120e0b56f08c119a4a8 214 PANTHER PTHR30173 2 185 2.4E-40 T 23-04-2016 DC74_RS37145 578a18c573513120e0b56f08c119a4a8 214 SUPERFAMILY SSF88946 9 118 2.86E-23 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37145 578a18c573513120e0b56f08c119a4a8 214 SUPERFAMILY SSF88659 122 185 1.66E-12 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS37145 578a18c573513120e0b56f08c119a4a8 214 Pfam PF04542 Sigma-70 region 2 31 98 1.5E-19 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS02460 471998ed39262129ec7a24e1263d31f1 288 PANTHER PTHR35010 2 288 7.3E-90 T 23-04-2016 DC74_RS02460 471998ed39262129ec7a24e1263d31f1 288 Gene3D G3DSA:1.10.260.40 14 92 3.0E-22 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS02460 471998ed39262129ec7a24e1263d31f1 288 Pfam PF13560 Helix-turn-helix domain 16 96 3.2E-18 T 23-04-2016 DC74_RS02460 471998ed39262129ec7a24e1263d31f1 288 SUPERFAMILY SSF47413 41 93 4.15E-10 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS02460 471998ed39262129ec7a24e1263d31f1 288 PANTHER PTHR35010:SF2 2 288 7.3E-90 T 23-04-2016 DC74_RS02460 471998ed39262129ec7a24e1263d31f1 288 SMART SM00530 20 93 4.8E-8 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS34360 303f4e2c0977127a2041da651b0c981a 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 46 5.9E-7 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS34360 303f4e2c0977127a2041da651b0c981a 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 5.9E-7 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS34360 303f4e2c0977127a2041da651b0c981a 123 Pfam PF12840 Helix-turn-helix domain 28 80 1.4E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34360 303f4e2c0977127a2041da651b0c981a 123 PANTHER PTHR33154 15 119 3.4E-39 T 23-04-2016 DC74_RS34360 303f4e2c0977127a2041da651b0c981a 123 PANTHER PTHR33154:SF2 15 119 3.4E-39 T 23-04-2016 DC74_RS34360 303f4e2c0977127a2041da651b0c981a 123 SUPERFAMILY SSF46785 16 107 2.98E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS34360 303f4e2c0977127a2041da651b0c981a 123 SMART SM00418 29 107 9.8E-15 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS34360 303f4e2c0977127a2041da651b0c981a 123 Gene3D G3DSA:1.10.10.10 19 106 3.9E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14860 b496469db25f3159fa50b663676fde02 158 Pfam PF01475 Ferric uptake regulator family 25 140 4.2E-31 T 23-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 DC74_RS14860 b496469db25f3159fa50b663676fde02 158 SUPERFAMILY SSF46785 25 145 1.09E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14860 b496469db25f3159fa50b663676fde02 158 Gene3D G3DSA:1.10.10.10 25 92 4.4E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS14860 b496469db25f3159fa50b663676fde02 158 PANTHER PTHR33202:SF5 25 148 1.8E-60 T 23-04-2016 DC74_RS14860 b496469db25f3159fa50b663676fde02 158 PANTHER PTHR33202 25 148 1.8E-60 T 23-04-2016 DC74_RS36080 130e93f65f15e9546346a292d80c7648 188 Pfam PF12867 DinB superfamily 20 171 9.7E-18 T 23-04-2016 IPR024775 DinB-like domain DC74_RS36080 130e93f65f15e9546346a292d80c7648 188 SUPERFAMILY SSF109854 15 165 2.04E-5 T 23-04-2016 DC74_RS36080 130e93f65f15e9546346a292d80c7648 188 Gene3D G3DSA:1.20.120.450 113 159 8.3E-4 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS27620 39fc5c5b0f12b82db377e6b774e8f725 94 Pfam PF04149 Domain of unknown function (DUF397) 34 91 1.6E-23 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS27620 39fc5c5b0f12b82db377e6b774e8f725 94 Pfam PF04149 Domain of unknown function (DUF397) 14 32 3.1E-7 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS21815 1828a321f28c139e36379014cb00acb7 498 Gene3D G3DSA:1.20.1250.20 254 417 4.9E-12 T 23-04-2016 DC74_RS21815 1828a321f28c139e36379014cb00acb7 498 Gene3D G3DSA:1.20.1250.20 10 187 1.7E-22 T 23-04-2016 DC74_RS21815 1828a321f28c139e36379014cb00acb7 498 PANTHER PTHR23501 11 428 3.6E-84 T 23-04-2016 DC74_RS21815 1828a321f28c139e36379014cb00acb7 498 Pfam PF07690 Major Facilitator Superfamily 16 406 1.4E-33 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS21815 1828a321f28c139e36379014cb00acb7 498 SUPERFAMILY SSF103473 245 416 3.14E-48 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21815 1828a321f28c139e36379014cb00acb7 498 SUPERFAMILY SSF103473 6 192 3.14E-48 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS24615 a23af30583b7d0f6d91167d32d6bf368 516 PANTHER PTHR11552 4 507 1.4E-190 T 23-04-2016 DC74_RS24615 a23af30583b7d0f6d91167d32d6bf368 516 SUPERFAMILY SSF51905 449 508 1.18E-66 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24615 a23af30583b7d0f6d91167d32d6bf368 516 SUPERFAMILY SSF51905 4 281 1.18E-66 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24615 a23af30583b7d0f6d91167d32d6bf368 516 Gene3D G3DSA:3.50.50.60 176 306 3.3E-102 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24615 a23af30583b7d0f6d91167d32d6bf368 516 Gene3D G3DSA:3.50.50.60 443 508 3.3E-102 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24615 a23af30583b7d0f6d91167d32d6bf368 516 Gene3D G3DSA:3.50.50.60 4 124 3.3E-102 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS24615 a23af30583b7d0f6d91167d32d6bf368 516 Pfam PF05199 GMC oxidoreductase 360 502 3.0E-36 T 23-04-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 DC74_RS24615 a23af30583b7d0f6d91167d32d6bf368 516 Pfam PF00732 GMC oxidoreductase 4 289 2.4E-56 T 23-04-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 DC74_RS24615 a23af30583b7d0f6d91167d32d6bf368 516 SUPERFAMILY SSF54373 283 450 2.65E-37 T 23-04-2016 DC74_RS24615 a23af30583b7d0f6d91167d32d6bf368 516 PANTHER PTHR11552:SF135 4 507 1.4E-190 T 23-04-2016 DC74_RS24615 a23af30583b7d0f6d91167d32d6bf368 516 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 247 261 - T 23-04-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 DC74_RS36750 59608aa0dc572a1cb6dfe2aeb0f93dca 614 PANTHER PTHR31956:SF12 268 534 1.1E-105 T 23-04-2016 DC74_RS36750 59608aa0dc572a1cb6dfe2aeb0f93dca 614 PANTHER PTHR31956:SF12 44 221 1.1E-105 T 23-04-2016 DC74_RS36750 59608aa0dc572a1cb6dfe2aeb0f93dca 614 PANTHER PTHR31956 268 534 1.1E-105 T 23-04-2016 DC74_RS36750 59608aa0dc572a1cb6dfe2aeb0f93dca 614 PANTHER PTHR31956 44 221 1.1E-105 T 23-04-2016 DC74_RS36750 59608aa0dc572a1cb6dfe2aeb0f93dca 614 Pfam PF04185 Phosphoesterase family 48 510 1.4E-78 T 23-04-2016 IPR007312 Phosphoesterase GO:0016788 DC74_RS18790 816a9e807ab6473270913621de33ebf6 270 SUPERFAMILY SSF89392 38 259 1.29E-10 T 23-04-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX DC74_RS10285 5a2da848548129589db28fd721829b6d 123 PANTHER PTHR10516 19 123 1.1E-45 T 23-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type DC74_RS10285 5a2da848548129589db28fd721829b6d 123 Gene3D G3DSA:3.10.50.40 16 123 5.2E-42 T 23-04-2016 DC74_RS10285 5a2da848548129589db28fd721829b6d 123 SUPERFAMILY SSF54534 15 123 4.71E-41 T 23-04-2016 DC74_RS10285 5a2da848548129589db28fd721829b6d 123 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 31 120 4.8E-32 T 23-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 DC74_RS12300 98028da75000ce5d60988b53f6548991 423 PANTHER PTHR10314 22 401 1.3E-223 T 23-04-2016 DC74_RS12300 98028da75000ce5d60988b53f6548991 423 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 96 110 - T 23-04-2016 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS12300 98028da75000ce5d60988b53f6548991 423 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 67 393 1.8E-49 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS12300 98028da75000ce5d60988b53f6548991 423 Gene3D G3DSA:3.40.50.1100 114 192 5.3E-23 T 23-04-2016 DC74_RS12300 98028da75000ce5d60988b53f6548991 423 PIRSF PIRSF001413 10 410 6.2E-158 T 23-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS12300 98028da75000ce5d60988b53f6548991 423 Gene3D G3DSA:3.40.50.1100 193 407 5.8E-96 T 23-04-2016 DC74_RS12300 98028da75000ce5d60988b53f6548991 423 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 22 404 1.1E-182 T 23-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS12300 98028da75000ce5d60988b53f6548991 423 PANTHER PTHR10314:SF3 22 401 1.3E-223 T 23-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS12300 98028da75000ce5d60988b53f6548991 423 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 17 406 51.362 T 23-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 DC74_RS12300 98028da75000ce5d60988b53f6548991 423 SUPERFAMILY SSF53686 18 405 2.49E-144 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS35300 e7c0afebfb6d7dcf7237793923a98b77 317 Gene3D G3DSA:3.30.420.10 127 306 9.1E-47 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS35300 e7c0afebfb6d7dcf7237793923a98b77 317 SUPERFAMILY SSF53098 132 310 2.53E-38 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS35300 e7c0afebfb6d7dcf7237793923a98b77 317 SUPERFAMILY SSF46689 4 111 6.99E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS35300 e7c0afebfb6d7dcf7237793923a98b77 317 Pfam PF00665 Integrase core domain 132 268 5.8E-40 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 DC74_RS35300 e7c0afebfb6d7dcf7237793923a98b77 317 PANTHER PTHR24559 116 146 2.1E-27 T 23-04-2016 DC74_RS35300 e7c0afebfb6d7dcf7237793923a98b77 317 PANTHER PTHR24559 166 298 2.1E-27 T 23-04-2016 DC74_RS35300 e7c0afebfb6d7dcf7237793923a98b77 317 Pfam PF13011 leucine-zipper of insertion element IS481 3 82 2.1E-16 T 23-04-2016 IPR024967 DNA-binding domain, IS481-type DC74_RS36180 84450c59c914de7be84604e5ba2b40d4 419 Gene3D G3DSA:3.90.1720.10 264 371 5.3E-4 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS36180 84450c59c914de7be84604e5ba2b40d4 419 Pfam PF12671 Putative amidase domain 244 400 3.9E-16 T 23-04-2016 IPR024301 Putative amidase domain DC74_RS15270 bf35f27aabcf79c348e7ef3b4cffa4b6 309 Pfam PF04085 rod shape-determining protein MreC 129 270 5.9E-35 T 23-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 DC74_RS15270 bf35f27aabcf79c348e7ef3b4cffa4b6 309 PANTHER PTHR34138 1 307 3.4E-52 T 23-04-2016 DC74_RS15270 bf35f27aabcf79c348e7ef3b4cffa4b6 309 PIRSF PIRSF038471 2 282 4.5E-43 T 23-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 DC74_RS15270 bf35f27aabcf79c348e7ef3b4cffa4b6 309 PANTHER PTHR34138:SF1 1 307 3.4E-52 T 23-04-2016 DC74_RS20305 d920ea6e881e0b8a4926667508b159b4 212 Pfam PF14016 Protein of unknown function (DUF4232) 77 198 1.2E-9 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS04850 22eaba814b8bbfc5915f45b494972d07 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 8.0E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS04850 22eaba814b8bbfc5915f45b494972d07 201 SUPERFAMILY SSF48498 83 194 3.74E-21 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS04850 22eaba814b8bbfc5915f45b494972d07 201 Gene3D G3DSA:1.10.357.10 60 194 1.3E-30 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS04850 22eaba814b8bbfc5915f45b494972d07 201 PANTHER PTHR30328 5 194 8.9E-25 T 23-04-2016 DC74_RS04850 22eaba814b8bbfc5915f45b494972d07 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.3E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS04850 22eaba814b8bbfc5915f45b494972d07 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.3E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS04850 22eaba814b8bbfc5915f45b494972d07 201 Gene3D G3DSA:1.10.10.60 4 59 8.2E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS04850 22eaba814b8bbfc5915f45b494972d07 201 PANTHER PTHR30328:SF18 5 194 8.9E-25 T 23-04-2016 DC74_RS04850 22eaba814b8bbfc5915f45b494972d07 201 SUPERFAMILY SSF46689 3 77 1.08E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS22750 d221fcda4bd5ded4a32894b2fe9b6e06 329 Gene3D G3DSA:3.20.20.80 198 278 6.7E-5 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS22750 d221fcda4bd5ded4a32894b2fe9b6e06 329 SUPERFAMILY SSF51445 4 275 2.86E-17 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS32370 5b08b8102a8131bcece9a7da5dda09cc 339 PANTHER PTHR22604 1 318 2.6E-67 T 23-04-2016 DC74_RS32370 5b08b8102a8131bcece9a7da5dda09cc 339 SUPERFAMILY SSF51735 3 155 1.04E-46 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32370 5b08b8102a8131bcece9a7da5dda09cc 339 PANTHER PTHR22604:SF105 1 318 2.6E-67 T 23-04-2016 DC74_RS32370 5b08b8102a8131bcece9a7da5dda09cc 339 SUPERFAMILY SSF55347 129 295 7.36E-36 T 23-04-2016 DC74_RS32370 5b08b8102a8131bcece9a7da5dda09cc 339 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 1.1E-22 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 DC74_RS32370 5b08b8102a8131bcece9a7da5dda09cc 339 Gene3D G3DSA:3.40.50.720 1 145 5.0E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS32370 5b08b8102a8131bcece9a7da5dda09cc 339 Gene3D G3DSA:3.30.360.10 146 322 5.6E-35 T 23-04-2016 DC74_RS33780 881cb8c243af98a0802f8f6316587b96 408 SUPERFAMILY SSF50494 206 386 9.85E-23 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS33780 881cb8c243af98a0802f8f6316587b96 408 Gene3D G3DSA:3.30.300.50 121 194 8.7E-8 T 23-04-2016 DC74_RS33780 881cb8c243af98a0802f8f6316587b96 408 Gene3D G3DSA:2.40.10.10 292 396 5.1E-20 T 23-04-2016 DC74_RS33780 881cb8c243af98a0802f8f6316587b96 408 PIRSF PIRSF001134 1 407 1.0E-80 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS33780 881cb8c243af98a0802f8f6316587b96 408 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 232 246 1.2E-23 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS33780 881cb8c243af98a0802f8f6316587b96 408 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 339 362 1.2E-23 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS33780 881cb8c243af98a0802f8f6316587b96 408 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 299 319 1.2E-23 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS33780 881cb8c243af98a0802f8f6316587b96 408 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 320 337 1.2E-23 T 23-04-2016 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 DC74_RS33780 881cb8c243af98a0802f8f6316587b96 408 Gene3D G3DSA:3.30.300.50 42 120 2.1E-23 T 23-04-2016 DC74_RS33780 881cb8c243af98a0802f8f6316587b96 408 Gene3D G3DSA:2.40.10.10 204 291 3.4E-13 T 23-04-2016 DC74_RS33780 881cb8c243af98a0802f8f6316587b96 408 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 348 359 - T 23-04-2016 IPR033116 Serine proteases, trypsin family, serine active site DC74_RS33780 881cb8c243af98a0802f8f6316587b96 408 Pfam PF02983 Alpha-lytic protease prodomain 122 173 1.6E-6 T 23-04-2016 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 DC74_RS33350 f0cdc3c810401596841a747092d743f1 206 SUPERFAMILY SSF52540 23 200 1.01E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33350 f0cdc3c810401596841a747092d743f1 206 Gene3D G3DSA:3.40.50.300 23 191 1.5E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33350 f0cdc3c810401596841a747092d743f1 206 PANTHER PTHR11711 24 194 1.6E-53 T 23-04-2016 DC74_RS33350 f0cdc3c810401596841a747092d743f1 206 Pfam PF03029 Conserved hypothetical ATP binding protein 28 195 1.4E-26 T 23-04-2016 IPR004130 GPN-loop GTPase DC74_RS33350 f0cdc3c810401596841a747092d743f1 206 PANTHER PTHR11711:SF117 24 194 1.6E-53 T 23-04-2016 DC74_RS32770 6d747b1d422e51b5945722cc3e621c24 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 119 1.7E-7 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS32770 6d747b1d422e51b5945722cc3e621c24 124 SUPERFAMILY SSF54593 7 122 7.25E-21 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS32770 6d747b1d422e51b5945722cc3e621c24 124 Gene3D G3DSA:3.10.180.10 2 123 3.7E-25 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS21200 40b604354f7c9b1c9fe53e4059e47ee3 245 Pfam PF07987 Domain of unkown function (DUF1775) 40 187 1.4E-50 T 23-04-2016 IPR012533 GLE1, N-terminal, bacteria DC74_RS16630 7fcfc12a2410ee2b8bab052823a8615b 194 PANTHER PTHR35525 7 193 1.3E-42 T 23-04-2016 DC74_RS16630 7fcfc12a2410ee2b8bab052823a8615b 194 Pfam PF07336 Putative stress-induced transcription regulator 12 142 4.2E-19 T 23-04-2016 IPR010852 Putative stress-induced transcription regulator DC74_RS16630 7fcfc12a2410ee2b8bab052823a8615b 194 SUPERFAMILY SSF160904 8 189 3.79E-39 T 23-04-2016 DC74_RS16630 7fcfc12a2410ee2b8bab052823a8615b 194 PANTHER PTHR35525:SF3 7 193 1.3E-42 T 23-04-2016 DC74_RS16630 7fcfc12a2410ee2b8bab052823a8615b 194 Gene3D G3DSA:1.10.3300.10 8 189 1.4E-43 T 23-04-2016 IPR023286 ABATE domain DC74_RS16630 7fcfc12a2410ee2b8bab052823a8615b 194 Pfam PF11706 CGNR zinc finger 148 190 1.6E-17 T 23-04-2016 IPR021005 Zinc finger, CGNR DC74_RS34860 a7bda6b1f1b8579be048268b88d35d01 546 Gene3D G3DSA:3.40.50.300 260 483 2.8E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS34860 a7bda6b1f1b8579be048268b88d35d01 546 SUPERFAMILY SSF52540 245 486 2.53E-15 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS04285 c426ed789fa78244a0a097e945cbf6e1 547 Pfam PF01566 Natural resistance-associated macrophage protein 71 427 6.7E-78 T 23-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 DC74_RS12830 0dc6ec31b23419eacae1024f591e604e 226 PANTHER PTHR22936 1 203 2.1E-23 T 23-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 DC74_RS12830 0dc6ec31b23419eacae1024f591e604e 226 Pfam PF01694 Rhomboid family 56 206 2.2E-35 T 23-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 DC74_RS12830 0dc6ec31b23419eacae1024f591e604e 226 SUPERFAMILY SSF144091 2 204 2.49E-32 T 23-04-2016 DC74_RS12830 0dc6ec31b23419eacae1024f591e604e 226 Gene3D G3DSA:1.20.1540.10 2 203 2.4E-31 T 23-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 DC74_RS36040 cb7496ce314e4399317e51571159c768 202 SUPERFAMILY SSF109854 6 140 4.27E-14 T 23-04-2016 DC74_RS36040 cb7496ce314e4399317e51571159c768 202 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 194 1.6E-22 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS36040 cb7496ce314e4399317e51571159c768 202 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 135 2.8E-10 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS36040 cb7496ce314e4399317e51571159c768 202 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 9 194 1.5E-41 T 23-04-2016 IPR017520 Conserved hypothetical protein CHP03086 DC74_RS26050 06ba9903ee5a80b4057a79809abe7f2a 201 Pfam PF01914 MarC family integral membrane protein 6 197 7.5E-45 T 23-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 DC74_RS26050 06ba9903ee5a80b4057a79809abe7f2a 201 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 5 194 9.5E-42 T 23-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 DC74_RS26050 06ba9903ee5a80b4057a79809abe7f2a 201 PANTHER PTHR33508:SF1 1 200 1.2E-65 T 23-04-2016 DC74_RS26050 06ba9903ee5a80b4057a79809abe7f2a 201 PANTHER PTHR33508 1 200 1.2E-65 T 23-04-2016 DC74_RS20115 81ad7567c4b96126b00c1a13b0144d04 321 Gene3D G3DSA:3.30.2010.10 127 192 1.1E-14 T 23-04-2016 DC74_RS20115 81ad7567c4b96126b00c1a13b0144d04 321 Pfam PF01435 Peptidase family M48 128 194 6.3E-7 T 23-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DC74_RS17195 5c9803c31814aab4ab32fc87c87b9764 162 SUPERFAMILY SSF55874 67 158 7.19E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17195 5c9803c31814aab4ab32fc87c87b9764 162 Gene3D G3DSA:3.30.565.10 58 159 7.0E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS17195 5c9803c31814aab4ab32fc87c87b9764 162 Pfam PF13581 Histidine kinase-like ATPase domain 40 155 4.3E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS02180 d39cdcf1531dda87f53c65247e34f967 380 PANTHER PTHR23028 1 350 6.1E-25 T 23-04-2016 DC74_RS02180 d39cdcf1531dda87f53c65247e34f967 380 Pfam PF01757 Acyltransferase family 1 334 1.8E-28 T 23-04-2016 IPR002656 Acyltransferase 3 GO:0016747 DC74_RS00445 b5e370949e317cf65c41b9ecf6834409 357 Gene3D G3DSA:3.40.50.720 168 303 5.7E-16 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00445 b5e370949e317cf65c41b9ecf6834409 357 PANTHER PTHR11695:SF607 8 340 8.4E-83 T 23-04-2016 DC74_RS00445 b5e370949e317cf65c41b9ecf6834409 357 SUPERFAMILY SSF51735 147 320 5.23E-19 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00445 b5e370949e317cf65c41b9ecf6834409 357 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 21 133 5.1E-9 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DC74_RS00445 b5e370949e317cf65c41b9ecf6834409 357 PANTHER PTHR11695 8 340 8.4E-83 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 DC74_RS00445 b5e370949e317cf65c41b9ecf6834409 357 SUPERFAMILY SSF50129 2 178 7.91E-27 T 23-04-2016 IPR011032 GroES-like DC74_RS00445 b5e370949e317cf65c41b9ecf6834409 357 SMART SM00829 5 345 0.0049 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DC74_RS00445 b5e370949e317cf65c41b9ecf6834409 357 Gene3D G3DSA:3.90.180.10 114 167 1.3E-22 T 23-04-2016 IPR011032 GroES-like DC74_RS00445 b5e370949e317cf65c41b9ecf6834409 357 Gene3D G3DSA:3.90.180.10 2 82 1.3E-22 T 23-04-2016 IPR011032 GroES-like DC74_RS40155 a75c6ba0112496931a3af2b2c46e0dc6 239 SUPERFAMILY SSF53335 8 227 2.37E-23 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40155 a75c6ba0112496931a3af2b2c46e0dc6 239 Gene3D G3DSA:3.40.50.150 19 216 7.8E-22 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40155 a75c6ba0112496931a3af2b2c46e0dc6 239 Pfam PF13649 Methyltransferase domain 39 130 6.2E-13 T 23-04-2016 DC74_RS14510 ceb8230132f526976a8089feaca4b5e7 303 SUPERFAMILY SSF110849 27 125 1.83E-9 T 23-04-2016 IPR003115 ParB/Sulfiredoxin DC74_RS14510 ceb8230132f526976a8089feaca4b5e7 303 Gene3D G3DSA:3.90.1530.10 34 108 4.1E-6 T 23-04-2016 DC74_RS14510 ceb8230132f526976a8089feaca4b5e7 303 Pfam PF02195 ParB-like nuclease domain 35 108 1.1E-4 T 23-04-2016 IPR003115 ParB/Sulfiredoxin DC74_RS14950 508b01d69e5f03f79103f1887378835c 116 SUPERFAMILY SSF53927 12 111 8.28E-12 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS14950 508b01d69e5f03f79103f1887378835c 116 Gene3D G3DSA:3.40.140.10 11 112 1.9E-8 T 23-04-2016 DC74_RS06090 5cd408ec206edfd28337cbe803481ea2 354 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 216 229 2.0E-14 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 DC74_RS06090 5cd408ec206edfd28337cbe803481ea2 354 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 130 141 2.0E-14 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 DC74_RS06090 5cd408ec206edfd28337cbe803481ea2 354 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 183 200 2.0E-14 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 DC74_RS06090 5cd408ec206edfd28337cbe803481ea2 354 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 93 337 1.4E-39 T 23-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 DC74_RS06090 5cd408ec206edfd28337cbe803481ea2 354 PANTHER PTHR21581:SF1 88 354 1.8E-56 T 23-04-2016 DC74_RS06090 5cd408ec206edfd28337cbe803481ea2 354 Gene3D G3DSA:3.40.710.10 95 353 7.7E-81 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS06090 5cd408ec206edfd28337cbe803481ea2 354 SUPERFAMILY SSF56601 83 353 5.9E-55 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS06090 5cd408ec206edfd28337cbe803481ea2 354 PANTHER PTHR21581 88 354 1.8E-56 T 23-04-2016 DC74_RS19190 9ac547b41c245e56d1a87b0b8662283a 644 Gene3D G3DSA:3.40.50.980 57 223 6.7E-32 T 23-04-2016 DC74_RS19190 9ac547b41c245e56d1a87b0b8662283a 644 Pfam PF00501 AMP-binding enzyme 58 512 4.9E-87 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS19190 9ac547b41c245e56d1a87b0b8662283a 644 SUPERFAMILY SSF56801 381 642 9.29E-107 T 23-04-2016 DC74_RS19190 9ac547b41c245e56d1a87b0b8662283a 644 SUPERFAMILY SSF56801 26 327 9.29E-107 T 23-04-2016 DC74_RS19190 9ac547b41c245e56d1a87b0b8662283a 644 Gene3D G3DSA:3.30.300.30 510 629 8.8E-6 T 23-04-2016 DC74_RS19190 9ac547b41c245e56d1a87b0b8662283a 644 PANTHER PTHR24096:SF193 48 644 1.9E-186 T 23-04-2016 DC74_RS19190 9ac547b41c245e56d1a87b0b8662283a 644 PANTHER PTHR24096 48 644 1.9E-186 T 23-04-2016 DC74_RS19190 9ac547b41c245e56d1a87b0b8662283a 644 Gene3D G3DSA:3.40.50.980 378 438 1.1E-26 T 23-04-2016 DC74_RS19190 9ac547b41c245e56d1a87b0b8662283a 644 Gene3D G3DSA:3.40.50.980 224 322 1.1E-26 T 23-04-2016 DC74_RS19190 9ac547b41c245e56d1a87b0b8662283a 644 ProSitePatterns PS00455 Putative AMP-binding domain signature. 217 228 - T 23-04-2016 IPR020845 AMP-binding, conserved site DC74_RS19190 9ac547b41c245e56d1a87b0b8662283a 644 Gene3D G3DSA:2.30.38.10 439 503 1.4E-15 T 23-04-2016 DC74_RS37535 c179117f2e6e98689475fe88a654e782 194 Pfam PF04978 Protein of unknown function (DUF664) 10 158 2.2E-43 T 23-04-2016 IPR007061 Protein of unknown function DUF664 DC74_RS37535 c179117f2e6e98689475fe88a654e782 194 SUPERFAMILY SSF109854 8 157 1.43E-35 T 23-04-2016 DC74_RS37535 c179117f2e6e98689475fe88a654e782 194 Gene3D G3DSA:1.20.120.450 10 161 1.3E-30 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS29070 a1e69bf4a420ab2c83b0df78fefbd7c8 219 Gene3D G3DSA:1.20.120.530 63 193 2.5E-28 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS29070 a1e69bf4a420ab2c83b0df78fefbd7c8 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 49 1.8E-5 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS29070 a1e69bf4a420ab2c83b0df78fefbd7c8 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 19 33 1.8E-5 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS29070 a1e69bf4a420ab2c83b0df78fefbd7c8 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 57 2.0E-15 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS29070 a1e69bf4a420ab2c83b0df78fefbd7c8 219 SUPERFAMILY SSF46785 2 63 4.55E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29070 a1e69bf4a420ab2c83b0df78fefbd7c8 219 SMART SM00345 1 59 1.7E-17 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS29070 a1e69bf4a420ab2c83b0df78fefbd7c8 219 SUPERFAMILY SSF48008 66 195 5.49E-27 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal DC74_RS29070 a1e69bf4a420ab2c83b0df78fefbd7c8 219 PANTHER PTHR11751 4 85 5.6E-24 T 23-04-2016 DC74_RS29070 a1e69bf4a420ab2c83b0df78fefbd7c8 219 Pfam PF07729 FCD domain 69 191 5.6E-26 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS29070 a1e69bf4a420ab2c83b0df78fefbd7c8 219 Gene3D G3DSA:1.10.10.10 2 60 5.3E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29070 a1e69bf4a420ab2c83b0df78fefbd7c8 219 SMART SM00895 69 191 7.8E-23 T 23-04-2016 IPR011711 GntR, C-terminal DC74_RS20385 5290a05b04e413de940b4ef56171cc46 182 Pfam PF10759 Protein of unknown function (DUF2587) 32 181 4.1E-80 T 23-04-2016 IPR019695 Bacterial proteasome activator GO:0061136 DC74_RS36330 3e37c932a898f3a246e3ad40fb0c3e76 283 PANTHER PTHR11941 1 75 1.2E-83 T 23-04-2016 DC74_RS36330 3e37c932a898f3a246e3ad40fb0c3e76 283 PANTHER PTHR11941 94 242 1.2E-83 T 23-04-2016 DC74_RS36330 3e37c932a898f3a246e3ad40fb0c3e76 283 Pfam PF00378 Enoyl-CoA hydratase/isomerase 110 250 1.9E-28 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS36330 3e37c932a898f3a246e3ad40fb0c3e76 283 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 73 2.0E-10 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS36330 3e37c932a898f3a246e3ad40fb0c3e76 283 PANTHER PTHR11941:SF85 1 75 1.2E-83 T 23-04-2016 DC74_RS36330 3e37c932a898f3a246e3ad40fb0c3e76 283 PANTHER PTHR11941:SF85 94 242 1.2E-83 T 23-04-2016 DC74_RS36330 3e37c932a898f3a246e3ad40fb0c3e76 283 Gene3D G3DSA:3.90.226.10 3 259 2.5E-67 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS36330 3e37c932a898f3a246e3ad40fb0c3e76 283 SUPERFAMILY SSF52096 6 259 5.26E-67 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS08785 2d5fbaeed85ee5b0e8d309f5ba430251 166 SUPERFAMILY SSF55874 21 128 4.01E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS08785 2d5fbaeed85ee5b0e8d309f5ba430251 166 Pfam PF13581 Histidine kinase-like ATPase domain 14 126 2.5E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS38010 3502781e90f27350dd2a103e44c18d8f 263 SUPERFAMILY SSF55729 3 146 7.62E-9 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS38010 3502781e90f27350dd2a103e44c18d8f 263 Gene3D G3DSA:3.40.630.30 37 146 9.1E-8 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS38010 3502781e90f27350dd2a103e44c18d8f 263 Pfam PF00583 Acetyltransferase (GNAT) family 99 146 5.7E-5 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS04435 acc708ac488f026dc79980cebb585eb4 186 SUPERFAMILY SSF53822 52 162 2.59E-7 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS04435 acc708ac488f026dc79980cebb585eb4 186 Gene3D G3DSA:3.40.50.2300 53 162 3.5E-5 T 23-04-2016 DC74_RS34640 c8221c4e448e21f8ea101bca0f73eaa4 262 Pfam PF13490 Putative zinc-finger 9 39 5.4E-8 T 23-04-2016 IPR027383 Putative zinc-finger DC74_RS02790 86187f6666b3080dd9b8db2dc0d1d4b8 109 Pfam PF11239 Protein of unknown function (DUF3040) 4 89 1.0E-6 T 23-04-2016 IPR021401 Protein of unknown function DUF3040 DC74_RS11170 87e00732863d944188fcc1685e41a834 441 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 8 343 3.3E-126 T 23-04-2016 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase DC74_RS11170 87e00732863d944188fcc1685e41a834 441 SUPERFAMILY SSF51905 7 250 6.48E-17 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS11170 87e00732863d944188fcc1685e41a834 441 PANTHER PTHR23024:SF215 50 119 2.7E-40 T 23-04-2016 DC74_RS11170 87e00732863d944188fcc1685e41a834 441 Gene3D G3DSA:3.50.50.60 90 229 2.7E-12 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS11170 87e00732863d944188fcc1685e41a834 441 PANTHER PTHR23024 50 119 2.7E-40 T 23-04-2016 DC74_RS14150 7cb54dff0b4eec021a95820a4bc046a3 241 PANTHER PTHR10108 206 239 7.5E-16 T 23-04-2016 DC74_RS14150 7cb54dff0b4eec021a95820a4bc046a3 241 PANTHER PTHR10108 32 148 7.5E-16 T 23-04-2016 DC74_RS14150 7cb54dff0b4eec021a95820a4bc046a3 241 Gene3D G3DSA:3.40.50.150 38 168 9.3E-24 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14150 7cb54dff0b4eec021a95820a4bc046a3 241 SUPERFAMILY SSF53335 25 168 4.96E-26 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS14150 7cb54dff0b4eec021a95820a4bc046a3 241 Pfam PF08241 Methyltransferase domain 51 139 5.6E-16 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS34830 dc032d746265b3106ba3715b638fa550 188 PANTHER PTHR35335 6 188 1.4E-23 T 23-04-2016 DC74_RS34830 dc032d746265b3106ba3715b638fa550 188 Pfam PF04186 FxsA cytoplasmic membrane protein 26 137 2.8E-26 T 23-04-2016 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 DC74_RS34830 dc032d746265b3106ba3715b638fa550 188 PANTHER PTHR35335:SF1 6 188 1.4E-23 T 23-04-2016 DC74_RS27285 2ccc09001d9380376c66636330f9323b 857 PANTHER PTHR30489:SF9 249 857 1.4E-189 T 23-04-2016 DC74_RS27285 2ccc09001d9380376c66636330f9323b 857 PANTHER PTHR30489:SF9 1 199 1.4E-189 T 23-04-2016 DC74_RS27285 2ccc09001d9380376c66636330f9323b 857 Pfam PF12704 MacB-like periplasmic core domain 17 240 4.1E-13 T 23-04-2016 IPR025857 MacB-like periplasmic core domain DC74_RS27285 2ccc09001d9380376c66636330f9323b 857 Pfam PF12704 MacB-like periplasmic core domain 498 699 1.3E-9 T 23-04-2016 IPR025857 MacB-like periplasmic core domain DC74_RS27285 2ccc09001d9380376c66636330f9323b 857 PANTHER PTHR30489 249 857 1.4E-189 T 23-04-2016 DC74_RS27285 2ccc09001d9380376c66636330f9323b 857 PANTHER PTHR30489 1 199 1.4E-189 T 23-04-2016 DC74_RS27285 2ccc09001d9380376c66636330f9323b 857 Pfam PF02687 FtsX-like permease family 733 849 5.1E-19 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS27285 2ccc09001d9380376c66636330f9323b 857 Pfam PF02687 FtsX-like permease family 276 396 4.2E-25 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS33660 8a2bfb45da18abf3982864515e2757c2 185 SUPERFAMILY SSF52540 2 152 6.88E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS33660 8a2bfb45da18abf3982864515e2757c2 185 Gene3D G3DSA:3.40.50.300 2 65 2.7E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 Gene3D G3DSA:3.40.50.720 12 252 2.4E-74 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 SUPERFAMILY SSF51735 13 252 1.46E-75 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 6.3E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 6.3E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 6.3E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 6.3E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 6.3E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 6.3E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 250 8.9E-56 T 23-04-2016 DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 PANTHER PTHR24322 161 191 4.6E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 PANTHER PTHR24322 18 145 4.6E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.3E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 2.3E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS07585 232dd1ae3fbb4f2a7235d4716ee9ce45 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 2.3E-11 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS20915 4abdd616639a1927814dc248311f9626 211 SUPERFAMILY SSF56784 2 208 9.08E-18 T 23-04-2016 IPR023214 HAD-like domain DC74_RS20915 4abdd616639a1927814dc248311f9626 211 Gene3D G3DSA:3.40.50.1000 76 194 3.6E-14 T 23-04-2016 IPR023214 HAD-like domain DC74_RS20915 4abdd616639a1927814dc248311f9626 211 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 171 1.5E-10 T 23-04-2016 DC74_RS20915 4abdd616639a1927814dc248311f9626 211 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 174 1.5E-12 T 23-04-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 DC74_RS17355 8f49298b83cb9062ee07345555d1e073 163 Pfam PF04977 Septum formation initiator 42 119 4.9E-14 T 23-04-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 DC74_RS23250 524b129cb9efee023343a10384524f6d 409 Pfam PF05235 CHAD domain 73 359 1.9E-18 T 23-04-2016 IPR007899 CHAD domain DC74_RS23250 524b129cb9efee023343a10384524f6d 409 SMART SM00880 70 393 9.0E-5 T 23-04-2016 IPR007899 CHAD domain DC74_RS19735 7310ebed6911a2c5ea25caf3ff36d9a8 106 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 105 4.0E-45 T 23-04-2016 IPR024412 Lsr2 DC74_RS19735 7310ebed6911a2c5ea25caf3ff36d9a8 106 Pfam PF11774 Lsr2 2 104 9.7E-35 T 23-04-2016 IPR024412 Lsr2 DC74_RS26425 3297cbc6b19a869711dd7b5704906ea8 85 PANTHER PTHR40034 16 82 1.1E-18 T 23-04-2016 DC74_RS26425 3297cbc6b19a869711dd7b5704906ea8 85 Pfam PF11755 Protein of unknown function (DUF3311) 24 81 1.6E-24 T 23-04-2016 IPR021741 Protein of unknown function DUF3311 DC74_RS26425 3297cbc6b19a869711dd7b5704906ea8 85 PANTHER PTHR40034:SF1 16 82 1.1E-18 T 23-04-2016 DC74_RS40420 047e7e8f2d8e88bc3367eae701ad1bee 301 Gene3D G3DSA:1.10.260.40 37 82 1.9E-6 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS40420 047e7e8f2d8e88bc3367eae701ad1bee 301 Pfam PF01381 Helix-turn-helix 43 82 3.7E-5 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS40420 047e7e8f2d8e88bc3367eae701ad1bee 301 SUPERFAMILY SSF47413 32 82 7.62E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS06005 89c7592c8984ddb8bcd31bee734f38fc 65 SUPERFAMILY SSF160582 4 55 1.96E-13 T 23-04-2016 DC74_RS06005 89c7592c8984ddb8bcd31bee734f38fc 65 Gene3D G3DSA:3.90.820.10 12 55 5.9E-10 T 23-04-2016 DC74_RS06005 89c7592c8984ddb8bcd31bee734f38fc 65 Pfam PF03621 MbtH-like protein 4 54 1.4E-14 T 23-04-2016 IPR005153 MbtH-like protein DC74_RS06005 89c7592c8984ddb8bcd31bee734f38fc 65 SMART SM00923 4 54 6.4E-9 T 23-04-2016 IPR005153 MbtH-like protein DC74_RS37705 ef297ba08ef4c4f15dbcc2fc087b7759 213 Pfam PF03413 Peptidase propeptide and YPEB domain 142 193 7.2E-7 T 23-04-2016 IPR025711 PepSY domain DC74_RS37705 ef297ba08ef4c4f15dbcc2fc087b7759 213 Pfam PF03413 Peptidase propeptide and YPEB domain 60 117 5.8E-8 T 23-04-2016 IPR025711 PepSY domain DC74_RS04095 6a260a4baeeb341dc1ae400875454b45 167 SUPERFAMILY SSF54001 8 148 9.81E-14 T 23-04-2016 DC74_RS04095 6a260a4baeeb341dc1ae400875454b45 167 Gene3D G3DSA:2.30.30.330 8 149 4.9E-15 T 23-04-2016 DC74_RS08060 6584a3a1e25013d1f4536462b9610052 515 PIRSF PIRSF012666 1 498 2.4E-211 T 23-04-2016 IPR016602 Uncharacterised conserved protein UCP012666 DC74_RS08060 6584a3a1e25013d1f4536462b9610052 515 SUPERFAMILY SSF55931 37 462 5.69E-50 T 23-04-2016 DC74_RS08060 6584a3a1e25013d1f4536462b9610052 515 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 62 250 4.3E-6 T 23-04-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 DC74_RS32515 e43b7566d1bcfaab18e5eb223e7b182f 71 Gene3D G3DSA:3.40.630.30 14 71 1.1E-6 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS34415 be7e18bed0d10b7f90b58da4669f63f7 393 Gene3D G3DSA:1.20.1250.20 6 176 7.6E-8 T 23-04-2016 DC74_RS34415 be7e18bed0d10b7f90b58da4669f63f7 393 Gene3D G3DSA:1.20.1250.20 200 378 1.5E-6 T 23-04-2016 DC74_RS34415 be7e18bed0d10b7f90b58da4669f63f7 393 SUPERFAMILY SSF103473 3 373 3.14E-26 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS34415 be7e18bed0d10b7f90b58da4669f63f7 393 PANTHER PTHR23514 1 375 5.4E-23 T 23-04-2016 DC74_RS22025 ef286845bc8eedf5973d442d324f3a55 325 PANTHER PTHR10803 1 245 3.4E-130 T 23-04-2016 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 DC74_RS22025 ef286845bc8eedf5973d442d324f3a55 325 Pfam PF02374 Anion-transporting ATPase 6 180 2.8E-19 T 23-04-2016 IPR025723 Anion-transporting ATPase-like domain DC74_RS22025 ef286845bc8eedf5973d442d324f3a55 325 PANTHER PTHR10803:SF6 1 245 3.4E-130 T 23-04-2016 DC74_RS22025 ef286845bc8eedf5973d442d324f3a55 325 Gene3D G3DSA:3.40.50.300 4 228 2.6E-36 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22025 ef286845bc8eedf5973d442d324f3a55 325 SUPERFAMILY SSF52540 4 225 5.7E-30 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39770 b5961a846493fe35ec7966732100f566 459 SUPERFAMILY SSF48371 188 382 1.11E-9 T 23-04-2016 IPR016024 Armadillo-type fold GO:0005488 DC74_RS39770 b5961a846493fe35ec7966732100f566 459 Gene3D G3DSA:1.25.10.10 198 416 4.2E-7 T 23-04-2016 IPR011989 Armadillo-like helical DC74_RS11805 3d5358ae123f0c58cec6629162ef7e8b 424 PANTHER PTHR23513 1 403 1.8E-52 T 23-04-2016 DC74_RS11805 3d5358ae123f0c58cec6629162ef7e8b 424 Pfam PF05977 Transmembrane secretion effector 21 401 8.9E-23 T 23-04-2016 IPR010290 Transmembrane secretion effector DC74_RS11805 3d5358ae123f0c58cec6629162ef7e8b 424 SUPERFAMILY SSF103473 23 407 4.05E-33 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS11805 3d5358ae123f0c58cec6629162ef7e8b 424 Gene3D G3DSA:1.20.1250.20 226 406 9.4E-11 T 23-04-2016 DC74_RS11805 3d5358ae123f0c58cec6629162ef7e8b 424 Gene3D G3DSA:1.20.1250.20 24 200 1.4E-9 T 23-04-2016 DC74_RS34350 bde8bcb532cf9af58e91810cb393c6fa 361 Gene3D G3DSA:2.130.10.10 6 356 9.5E-81 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 DC74_RS34350 bde8bcb532cf9af58e91810cb393c6fa 361 SUPERFAMILY SSF110296 3 357 2.09E-58 T 23-04-2016 DC74_RS21125 a685a3d06b77d8c6d88c293e99fed144 152 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 110 1.5E-16 T 23-04-2016 DC74_RS21125 a685a3d06b77d8c6d88c293e99fed144 152 SUPERFAMILY SSF54593 2 152 4.3E-12 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS21125 a685a3d06b77d8c6d88c293e99fed144 152 Gene3D G3DSA:3.10.180.10 3 123 2.4E-9 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS03260 b964a9547c4b583bbe8b799f44b5c0fc 132 Pfam PF14534 Domain of unknown function (DUF4440) 6 123 3.5E-13 T 23-04-2016 IPR027843 Domain of unknown function DUF4440 DC74_RS03260 b964a9547c4b583bbe8b799f44b5c0fc 132 SUPERFAMILY SSF54427 4 127 1.61E-15 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS03260 b964a9547c4b583bbe8b799f44b5c0fc 132 Gene3D G3DSA:3.10.450.50 4 125 1.7E-7 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS15960 4e2aefab06bfe170dd7f08f234dc8edd 216 PANTHER PTHR15020 3 216 6.8E-60 T 23-04-2016 DC74_RS15960 4e2aefab06bfe170dd7f08f234dc8edd 216 SUPERFAMILY SSF51735 1 215 2.86E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15960 4e2aefab06bfe170dd7f08f234dc8edd 216 Gene3D G3DSA:3.40.50.720 1 216 4.2E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS15960 4e2aefab06bfe170dd7f08f234dc8edd 216 PANTHER PTHR15020:SF29 3 216 6.8E-60 T 23-04-2016 DC74_RS15960 4e2aefab06bfe170dd7f08f234dc8edd 216 Pfam PF13460 NAD(P)H-binding 8 201 2.0E-31 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS36365 7fa64ad6b68ae2701d5da7d829346802 242 SUPERFAMILY SSF100950 3 238 3.27E-52 T 23-04-2016 DC74_RS36365 7fa64ad6b68ae2701d5da7d829346802 242 Gene3D G3DSA:3.40.810.20 3 239 5.2E-67 T 23-04-2016 DC74_RS36365 7fa64ad6b68ae2701d5da7d829346802 242 Pfam PF01144 Coenzyme A transferase 82 201 3.5E-7 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 DC74_RS36365 7fa64ad6b68ae2701d5da7d829346802 242 SMART SM00882 6 201 1.3E-4 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 DC74_RS34145 fec2f0dba534d35e496017bba63ab0bf 271 Pfam PF08241 Methyltransferase domain 54 146 1.3E-15 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS34145 fec2f0dba534d35e496017bba63ab0bf 271 PANTHER PTHR10108 8 146 4.6E-23 T 23-04-2016 DC74_RS34145 fec2f0dba534d35e496017bba63ab0bf 271 Gene3D G3DSA:3.40.50.150 5 152 1.0E-27 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS34145 fec2f0dba534d35e496017bba63ab0bf 271 SUPERFAMILY SSF53335 9 173 2.56E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS00440 84e9b5d76c81ab8a2246e191bcd32d90 105 SUPERFAMILY SSF48576 17 98 1.15E-12 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS00440 84e9b5d76c81ab8a2246e191bcd32d90 105 Gene3D G3DSA:1.10.600.10 17 97 4.3E-12 T 23-04-2016 IPR008949 Isoprenoid synthase domain DC74_RS00440 84e9b5d76c81ab8a2246e191bcd32d90 105 Pfam PF00348 Polyprenyl synthetase 19 97 4.3E-7 T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 DC74_RS40105 d2559145ca51ee5c84b02c71d74871c5 112 Pfam PF14016 Protein of unknown function (DUF4232) 4 108 2.2E-20 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS36685 71fa8e2a772dbffbfcb862622aeb3fe9 370 PANTHER PTHR21021 99 369 5.1E-36 T 23-04-2016 DC74_RS36685 71fa8e2a772dbffbfcb862622aeb3fe9 370 PANTHER PTHR21021:SF19 99 369 5.1E-36 T 23-04-2016 DC74_RS36685 71fa8e2a772dbffbfcb862622aeb3fe9 370 SUPERFAMILY SSF81606 156 360 9.68E-8 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS36685 71fa8e2a772dbffbfcb862622aeb3fe9 370 SMART SM00331 143 363 7.4E-36 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS36685 71fa8e2a772dbffbfcb862622aeb3fe9 370 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 170 363 1.3E-42 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS20020 290c1d10fea21a468f4fcc73b6a065d5 194 Gene3D G3DSA:1.10.10.10 121 180 1.9E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20020 290c1d10fea21a468f4fcc73b6a065d5 194 Pfam PF04542 Sigma-70 region 2 28 96 3.9E-16 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS20020 290c1d10fea21a468f4fcc73b6a065d5 194 Gene3D G3DSA:1.10.1740.10 25 115 2.2E-19 T 23-04-2016 DC74_RS20020 290c1d10fea21a468f4fcc73b6a065d5 194 SUPERFAMILY SSF88659 115 179 4.49E-14 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS20020 290c1d10fea21a468f4fcc73b6a065d5 194 PANTHER PTHR30173 1 180 6.5E-40 T 23-04-2016 DC74_RS20020 290c1d10fea21a468f4fcc73b6a065d5 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 179 5.3E-25 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS20020 290c1d10fea21a468f4fcc73b6a065d5 194 SUPERFAMILY SSF88946 23 108 4.71E-19 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS20020 290c1d10fea21a468f4fcc73b6a065d5 194 Pfam PF08281 Sigma-70, region 4 123 174 5.1E-10 T 23-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS20020 290c1d10fea21a468f4fcc73b6a065d5 194 PANTHER PTHR30173:SF17 1 180 6.5E-40 T 23-04-2016 DC74_RS34845 b05101331f0ae0a4924ebfb7813ed9eb 267 PANTHER PTHR23344:SF10 21 262 2.4E-58 T 23-04-2016 DC74_RS34845 b05101331f0ae0a4924ebfb7813ed9eb 267 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 22 253 2.6E-38 T 23-04-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 DC74_RS34845 b05101331f0ae0a4924ebfb7813ed9eb 267 SUPERFAMILY SSF51695 16 258 9.63E-59 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS34845 b05101331f0ae0a4924ebfb7813ed9eb 267 Gene3D G3DSA:3.20.20.190 14 266 1.3E-70 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 DC74_RS34845 b05101331f0ae0a4924ebfb7813ed9eb 267 PANTHER PTHR23344 21 262 2.4E-58 T 23-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 DC74_RS39830 28e1dfe10731a121d9b63af5bba329b5 266 Pfam PF01925 Sulfite exporter TauE/SafE 3 249 2.3E-25 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 DC74_RS08680 0e7dc445f8c80e6801cb205f32c1144d 144 SMART SM00116 14 62 1.8E-4 T 23-04-2016 IPR000644 CBS domain DC74_RS08680 0e7dc445f8c80e6801cb205f32c1144d 144 SMART SM00116 79 129 6.3E-6 T 23-04-2016 IPR000644 CBS domain DC74_RS08680 0e7dc445f8c80e6801cb205f32c1144d 144 Gene3D G3DSA:3.10.580.10 5 126 3.1E-27 T 23-04-2016 DC74_RS08680 0e7dc445f8c80e6801cb205f32c1144d 144 Pfam PF00571 CBS domain 78 128 3.8E-7 T 23-04-2016 IPR000644 CBS domain DC74_RS08680 0e7dc445f8c80e6801cb205f32c1144d 144 Pfam PF00571 CBS domain 7 58 6.3E-10 T 23-04-2016 IPR000644 CBS domain DC74_RS08680 0e7dc445f8c80e6801cb205f32c1144d 144 PANTHER PTHR11911 3 128 3.5E-23 T 23-04-2016 DC74_RS08680 0e7dc445f8c80e6801cb205f32c1144d 144 SUPERFAMILY SSF54631 5 134 2.65E-28 T 23-04-2016 DC74_RS02660 cc43b80c9a74c9d3e4f9cf3eafd53f28 175 SUPERFAMILY SSF55874 75 172 1.58E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33005 b1fbf1835779ee91e165e7ed12bc7928 388 PANTHER PTHR24023:SF545 10 17 2.4E-110 T 23-04-2016 DC74_RS33005 b1fbf1835779ee91e165e7ed12bc7928 388 PANTHER PTHR24023:SF545 48 370 2.4E-110 T 23-04-2016 DC74_RS33005 b1fbf1835779ee91e165e7ed12bc7928 388 Pfam PF02515 CoA-transferase family III 9 359 7.9E-84 T 23-04-2016 IPR003673 CoA-transferase family III GO:0003824 DC74_RS33005 b1fbf1835779ee91e165e7ed12bc7928 388 SUPERFAMILY SSF89796 4 368 1.31E-112 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS33005 b1fbf1835779ee91e165e7ed12bc7928 388 Gene3D G3DSA:3.30.1540.10 227 296 1.2E-10 T 23-04-2016 DC74_RS33005 b1fbf1835779ee91e165e7ed12bc7928 388 PANTHER PTHR24023 10 17 2.4E-110 T 23-04-2016 DC74_RS33005 b1fbf1835779ee91e165e7ed12bc7928 388 PANTHER PTHR24023 48 370 2.4E-110 T 23-04-2016 DC74_RS33005 b1fbf1835779ee91e165e7ed12bc7928 388 Gene3D G3DSA:3.40.50.10540 6 212 1.2E-93 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS33005 b1fbf1835779ee91e165e7ed12bc7928 388 Gene3D G3DSA:3.40.50.10540 297 367 1.2E-93 T 23-04-2016 IPR023606 CoA-transferase family III domain DC74_RS33990 f42a327c7df568cb15f1be3f49c1681e 305 Gene3D G3DSA:3.10.129.10 4 115 8.6E-50 T 23-04-2016 IPR029069 HotDog domain DC74_RS33990 f42a327c7df568cb15f1be3f49c1681e 305 SUPERFAMILY SSF54637 5 114 8.81E-43 T 23-04-2016 IPR029069 HotDog domain DC74_RS33990 f42a327c7df568cb15f1be3f49c1681e 305 PANTHER PTHR11066 8 302 1.5E-113 T 23-04-2016 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 DC74_RS33990 f42a327c7df568cb15f1be3f49c1681e 305 Gene3D G3DSA:3.10.129.10 125 286 5.5E-53 T 23-04-2016 IPR029069 HotDog domain DC74_RS33990 f42a327c7df568cb15f1be3f49c1681e 305 Pfam PF13622 Thioesterase-like superfamily 33 283 6.9E-62 T 23-04-2016 DC74_RS33990 f42a327c7df568cb15f1be3f49c1681e 305 SUPERFAMILY SSF54637 116 286 1.95E-50 T 23-04-2016 IPR029069 HotDog domain DC74_RS18985 a973427ee760b7a5e2dfa4b6cdf9c1d7 425 Gene3D G3DSA:2.50.20.10 136 302 3.5E-15 T 23-04-2016 DC74_RS18985 a973427ee760b7a5e2dfa4b6cdf9c1d7 425 SUPERFAMILY SSF89392 131 301 6.28E-13 T 23-04-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX DC74_RS04940 484aded266cdc585ba32d67395dc5609 551 Gene3D G3DSA:1.20.1250.20 52 203 1.0E-16 T 23-04-2016 DC74_RS04940 484aded266cdc585ba32d67395dc5609 551 PANTHER PTHR23513 5 434 4.0E-119 T 23-04-2016 DC74_RS04940 484aded266cdc585ba32d67395dc5609 551 SUPERFAMILY SSF103473 23 406 1.83E-44 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS04940 484aded266cdc585ba32d67395dc5609 551 Pfam PF05977 Transmembrane secretion effector 15 531 1.3E-148 T 23-04-2016 IPR010290 Transmembrane secretion effector DC74_RS04940 484aded266cdc585ba32d67395dc5609 551 PANTHER PTHR23513:SF7 5 434 4.0E-119 T 23-04-2016 DC74_RS04940 484aded266cdc585ba32d67395dc5609 551 Gene3D G3DSA:1.20.1250.20 247 402 8.7E-12 T 23-04-2016 DC74_RS34025 c5e492f30344a5e384a338f43414a854 477 PANTHER PTHR22604:SF2 73 296 1.4E-120 T 23-04-2016 DC74_RS34025 c5e492f30344a5e384a338f43414a854 477 PANTHER PTHR22604:SF2 315 465 1.4E-120 T 23-04-2016 DC74_RS34025 c5e492f30344a5e384a338f43414a854 477 SUPERFAMILY SSF51735 61 237 2.37E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS34025 c5e492f30344a5e384a338f43414a854 477 PANTHER PTHR22604 73 296 1.4E-120 T 23-04-2016 DC74_RS34025 c5e492f30344a5e384a338f43414a854 477 PANTHER PTHR22604 315 465 1.4E-120 T 23-04-2016 DC74_RS34025 c5e492f30344a5e384a338f43414a854 477 Gene3D G3DSA:3.40.50.720 77 260 4.3E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS34025 c5e492f30344a5e384a338f43414a854 477 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 78 201 1.3E-12 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 DC74_RS20040 c7a81fc4b0d29a3dd8dc0f0c5ac66399 378 SUPERFAMILY SSF56300 58 296 1.2E-28 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS20040 c7a81fc4b0d29a3dd8dc0f0c5ac66399 378 SUPERFAMILY SSF56300 3 17 1.2E-28 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like DC74_RS20040 c7a81fc4b0d29a3dd8dc0f0c5ac66399 378 SMART SM00854 7 288 9.0E-99 T 23-04-2016 IPR019079 Capsule synthesis protein, CapA DC74_RS20040 c7a81fc4b0d29a3dd8dc0f0c5ac66399 378 PANTHER PTHR33393 10 323 4.2E-59 T 23-04-2016 DC74_RS20040 c7a81fc4b0d29a3dd8dc0f0c5ac66399 378 Gene3D G3DSA:3.60.21.30 69 275 2.9E-9 T 23-04-2016 DC74_RS20040 c7a81fc4b0d29a3dd8dc0f0c5ac66399 378 PANTHER PTHR33393:SF2 10 323 4.2E-59 T 23-04-2016 DC74_RS20040 c7a81fc4b0d29a3dd8dc0f0c5ac66399 378 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 7 288 1.1E-68 T 23-04-2016 IPR019079 Capsule synthesis protein, CapA DC74_RS27095 223f12e89d437689c3298364ed535caa 895 PRINTS PR01217 Proline rich extensin signature 755 771 4.8E-9 T 23-04-2016 DC74_RS27095 223f12e89d437689c3298364ed535caa 895 PRINTS PR01217 Proline rich extensin signature 704 720 4.8E-9 T 23-04-2016 DC74_RS27095 223f12e89d437689c3298364ed535caa 895 PRINTS PR01217 Proline rich extensin signature 734 755 4.8E-9 T 23-04-2016 DC74_RS27095 223f12e89d437689c3298364ed535caa 895 PRINTS PR01217 Proline rich extensin signature 775 792 4.8E-9 T 23-04-2016 DC74_RS27095 223f12e89d437689c3298364ed535caa 895 PRINTS PR01217 Proline rich extensin signature 683 695 4.8E-9 T 23-04-2016 DC74_RS27095 223f12e89d437689c3298364ed535caa 895 SUPERFAMILY SSF52540 107 296 4.93E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 SUPERFAMILY SSF56672 158 558 4.34E-64 T 23-04-2016 DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 Gene3D G3DSA:1.10.150.20 338 478 1.7E-18 T 23-04-2016 DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 PRINTS PR00868 DNA-polymerase family A (pol I) signature 359 372 1.2E-9 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 PRINTS PR00868 DNA-polymerase family A (pol I) signature 471 487 1.2E-9 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 PRINTS PR00868 DNA-polymerase family A (pol I) signature 501 514 1.2E-9 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 PRINTS PR00868 DNA-polymerase family A (pol I) signature 329 352 1.2E-9 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 SMART SM00482 315 518 3.9E-12 T 23-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 Pfam PF00476 DNA polymerase family A 245 535 1.5E-29 T 23-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 PANTHER PTHR10133 120 131 2.7E-46 T 23-04-2016 DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 PANTHER PTHR10133 460 559 2.7E-46 T 23-04-2016 DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 PANTHER PTHR10133 230 442 2.7E-46 T 23-04-2016 DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 Gene3D G3DSA:3.30.70.370 298 337 6.2E-12 T 23-04-2016 DC74_RS22260 7ac55b6374408dad637e51028b7f3a75 559 Gene3D G3DSA:3.30.70.370 479 539 6.2E-12 T 23-04-2016 DC74_RS16075 8fdb71174762031fabeace1ff0f4502c 241 Pfam PF01177 Asp/Glu/Hydantoin racemase 53 217 5.7E-7 T 23-04-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS16075 8fdb71174762031fabeace1ff0f4502c 241 PIRSF PIRSF015736 2 240 2.6E-50 T 23-04-2016 IPR026286 Maleate isomerase/Arylmalonate decarboxylase DC74_RS16075 8fdb71174762031fabeace1ff0f4502c 241 PANTHER PTHR40267 1 237 4.0E-66 T 23-04-2016 DC74_RS21330 53f3e340f32d430770be935540642dc3 279 Pfam PF00892 EamA-like transporter family 141 277 1.0E-19 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS21330 53f3e340f32d430770be935540642dc3 279 Pfam PF00892 EamA-like transporter family 5 130 5.4E-17 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS21330 53f3e340f32d430770be935540642dc3 279 SUPERFAMILY SSF103481 43 131 2.62E-15 T 23-04-2016 DC74_RS21330 53f3e340f32d430770be935540642dc3 279 PANTHER PTHR32322:SF2 5 277 4.7E-42 T 23-04-2016 DC74_RS21330 53f3e340f32d430770be935540642dc3 279 PANTHER PTHR32322 5 277 4.7E-42 T 23-04-2016 DC74_RS21330 53f3e340f32d430770be935540642dc3 279 SUPERFAMILY SSF103481 179 277 2.48E-14 T 23-04-2016 DC74_RS37210 6f833a0db60c2c8a6c6c5a8107990742 135 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 90 134 0.007 T 23-04-2016 IPR024412 Lsr2 DC74_RS37210 6f833a0db60c2c8a6c6c5a8107990742 135 Pfam PF11774 Lsr2 85 131 3.2E-6 T 23-04-2016 IPR024412 Lsr2 DC74_RS35755 42a652c275a50dbecfc60daa84452d4a 377 PANTHER PTHR18964 9 366 5.4E-79 T 23-04-2016 DC74_RS35755 42a652c275a50dbecfc60daa84452d4a 377 SUPERFAMILY SSF53756 8 365 5.76E-87 T 23-04-2016 DC74_RS35755 42a652c275a50dbecfc60daa84452d4a 377 PANTHER PTHR18964:SF70 9 366 5.4E-79 T 23-04-2016 DC74_RS35755 42a652c275a50dbecfc60daa84452d4a 377 Gene3D G3DSA:3.40.50.2000 7 203 4.8E-60 T 23-04-2016 DC74_RS35755 42a652c275a50dbecfc60daa84452d4a 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 8 360 3.6E-78 T 23-04-2016 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 DC74_RS35755 42a652c275a50dbecfc60daa84452d4a 377 Gene3D G3DSA:3.40.50.2000 204 362 6.6E-41 T 23-04-2016 DC74_RS35755 42a652c275a50dbecfc60daa84452d4a 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 34 362 1.9E-86 T 23-04-2016 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain DC74_RS25520 7dac1a7ec834acfcee58876660800bd6 806 Pfam PF02687 FtsX-like permease family 687 791 5.1E-10 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS08560 ba25be70df0a4e7380b439c34b39331d 248 PANTHER PTHR11751 15 70 3.1E-15 T 23-04-2016 DC74_RS08560 ba25be70df0a4e7380b439c34b39331d 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 73 2.1E-16 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS08560 ba25be70df0a4e7380b439c34b39331d 248 SUPERFAMILY SSF46785 4 76 1.43E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS08560 ba25be70df0a4e7380b439c34b39331d 248 SMART SM00345 14 73 1.8E-17 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS08560 ba25be70df0a4e7380b439c34b39331d 248 SUPERFAMILY SSF64288 61 238 2.09E-8 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain DC74_RS08560 ba25be70df0a4e7380b439c34b39331d 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 8.9E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS08560 ba25be70df0a4e7380b439c34b39331d 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 8.9E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DC74_RS08560 ba25be70df0a4e7380b439c34b39331d 248 Gene3D G3DSA:1.10.10.10 9 75 2.1E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS33145 8c68505138008d982557c1ecb5d80be1 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 252 3.2E-41 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 DC74_RS33145 8c68505138008d982557c1ecb5d80be1 256 Gene3D G3DSA:3.90.226.10 5 252 2.0E-64 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS33145 8c68505138008d982557c1ecb5d80be1 256 PANTHER PTHR11941 1 251 9.3E-67 T 23-04-2016 DC74_RS33145 8c68505138008d982557c1ecb5d80be1 256 SUPERFAMILY SSF52096 5 252 6.74E-68 T 23-04-2016 IPR029045 ClpP/crotonase-like domain DC74_RS38535 a7b512155bd4e27453bd87ad9ff4f9e6 185 Pfam PF10400 Virulence activator alpha C-term 92 178 5.9E-25 T 23-04-2016 IPR018309 Transcription regulator PadR, C-terminal DC74_RS38535 a7b512155bd4e27453bd87ad9ff4f9e6 185 PANTHER PTHR33169:SF4 1 182 2.1E-55 T 23-04-2016 DC74_RS38535 a7b512155bd4e27453bd87ad9ff4f9e6 185 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 1.5E-13 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS38535 a7b512155bd4e27453bd87ad9ff4f9e6 185 PANTHER PTHR33169 1 182 2.1E-55 T 23-04-2016 DC74_RS38535 a7b512155bd4e27453bd87ad9ff4f9e6 185 SUPERFAMILY SSF46785 3 180 3.29E-42 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38535 a7b512155bd4e27453bd87ad9ff4f9e6 185 Gene3D G3DSA:1.10.10.10 1 88 4.0E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS11590 9628b563e402882c6249360d0eb7f824 300 PANTHER PTHR20883:SF0 24 298 2.2E-63 T 23-04-2016 DC74_RS11590 9628b563e402882c6249360d0eb7f824 300 SUPERFAMILY SSF51197 38 293 3.3E-58 T 23-04-2016 DC74_RS11590 9628b563e402882c6249360d0eb7f824 300 Gene3D G3DSA:2.60.120.620 36 277 2.0E-50 T 23-04-2016 DC74_RS11590 9628b563e402882c6249360d0eb7f824 300 PANTHER PTHR20883 24 298 2.2E-63 T 23-04-2016 DC74_RS11590 9628b563e402882c6249360d0eb7f824 300 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 47 262 2.8E-35 T 23-04-2016 IPR008775 Phytanoyl-CoA dioxygenase DC74_RS11590 9628b563e402882c6249360d0eb7f824 300 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 23 300 4.3E-148 T 23-04-2016 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 KEGG: 00260+1.14.11.-|KEGG: 00361+1.14.11.-|KEGG: 00904+1.14.11.- DC74_RS17170 163ef81eb2d561ea5dfa4ca2de262990 508 PANTHER PTHR11654:SF119 20 236 1.8E-143 T 23-04-2016 DC74_RS17170 163ef81eb2d561ea5dfa4ca2de262990 508 PANTHER PTHR11654:SF119 286 462 1.8E-143 T 23-04-2016 DC74_RS17170 163ef81eb2d561ea5dfa4ca2de262990 508 PANTHER PTHR11654 20 236 1.8E-143 T 23-04-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS17170 163ef81eb2d561ea5dfa4ca2de262990 508 PANTHER PTHR11654 286 462 1.8E-143 T 23-04-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS17170 163ef81eb2d561ea5dfa4ca2de262990 508 SUPERFAMILY SSF103473 22 223 5.1E-24 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS17170 163ef81eb2d561ea5dfa4ca2de262990 508 SUPERFAMILY SSF103473 291 499 5.1E-24 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS17170 163ef81eb2d561ea5dfa4ca2de262990 508 Gene3D G3DSA:1.20.1250.20 70 216 6.9E-9 T 23-04-2016 DC74_RS17170 163ef81eb2d561ea5dfa4ca2de262990 508 Gene3D G3DSA:1.20.1250.20 343 498 6.1E-5 T 23-04-2016 DC74_RS17170 163ef81eb2d561ea5dfa4ca2de262990 508 Pfam PF00854 POT family 107 462 1.3E-60 T 23-04-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS17170 163ef81eb2d561ea5dfa4ca2de262990 508 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 168 180 - T 23-04-2016 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: REACT_15518|Reactome: REACT_19419 DC74_RS17170 163ef81eb2d561ea5dfa4ca2de262990 508 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 504 1.1E-172 T 23-04-2016 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 DC74_RS29495 9a911c726756776b9741df01e97df444 338 Gene3D G3DSA:1.10.620.20 35 263 1.9E-10 T 23-04-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 DC74_RS29495 9a911c726756776b9741df01e97df444 338 SUPERFAMILY SSF47240 101 303 2.62E-56 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS29495 9a911c726756776b9741df01e97df444 338 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 133 312 8.4E-10 T 23-04-2016 IPR025859 P-aminobenzoate N-oxygenase AurF DC74_RS08775 aed17d288e4ff45b51f43a78fcd1e788 365 Gene3D G3DSA:3.40.50.1100 153 345 2.1E-35 T 23-04-2016 DC74_RS08775 aed17d288e4ff45b51f43a78fcd1e788 365 SUPERFAMILY SSF53686 32 346 1.7E-69 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS08775 aed17d288e4ff45b51f43a78fcd1e788 365 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 34 325 9.2E-45 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme DC74_RS08775 aed17d288e4ff45b51f43a78fcd1e788 365 PANTHER PTHR10314:SF126 4 357 1.5E-194 T 23-04-2016 DC74_RS08775 aed17d288e4ff45b51f43a78fcd1e788 365 Gene3D G3DSA:3.40.50.1100 57 152 1.6E-23 T 23-04-2016 DC74_RS08775 aed17d288e4ff45b51f43a78fcd1e788 365 PANTHER PTHR10314 4 357 1.5E-194 T 23-04-2016 DC74_RS26160 3fa3c32c74764f294c05ade18015b5ca 998 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 697 985 4.5E-29 T 23-04-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD DC74_RS26160 3fa3c32c74764f294c05ade18015b5ca 998 Gene3D G3DSA:1.10.510.10 469 535 1.0E-4 T 23-04-2016 DC74_RS26160 3fa3c32c74764f294c05ade18015b5ca 998 SUPERFAMILY SSF56112 429 535 1.45E-7 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS38905 41b76008ab3209326addbf2c0c240c25 196 Gene3D G3DSA:1.10.3480.10 13 154 1.5E-4 T 23-04-2016 IPR020945 DMSO/Nitrate reductase chaperone DC74_RS38905 41b76008ab3209326addbf2c0c240c25 196 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 13 159 1.0E-35 T 23-04-2016 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 DC74_RS38905 41b76008ab3209326addbf2c0c240c25 196 SUPERFAMILY SSF89155 7 165 2.49E-26 T 23-04-2016 IPR020945 DMSO/Nitrate reductase chaperone DC74_RS38905 41b76008ab3209326addbf2c0c240c25 196 PANTHER PTHR30598:SF1 9 167 7.6E-47 T 23-04-2016 DC74_RS38905 41b76008ab3209326addbf2c0c240c25 196 PANTHER PTHR30598 9 167 7.6E-47 T 23-04-2016 DC74_RS38905 41b76008ab3209326addbf2c0c240c25 196 Pfam PF02613 Nitrate reductase delta subunit 37 158 1.1E-10 T 23-04-2016 IPR020945 DMSO/Nitrate reductase chaperone DC74_RS08990 67021fbf1b4ec3837fa390394c18b407 311 PANTHER PTHR34978 1 305 6.9E-37 T 23-04-2016 DC74_RS08990 67021fbf1b4ec3837fa390394c18b407 311 Gene3D G3DSA:3.30.2010.10 142 199 5.7E-7 T 23-04-2016 DC74_RS08990 67021fbf1b4ec3837fa390394c18b407 311 Pfam PF01435 Peptidase family M48 162 229 6.8E-6 T 23-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DC74_RS21640 83dd76bdd6d0e7bca3e1bc37c41eda61 142 Pfam PF14437 MafB19-like deaminase 1 140 1.1E-30 T 23-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 DC74_RS21640 83dd76bdd6d0e7bca3e1bc37c41eda61 142 Gene3D G3DSA:3.40.140.10 1 141 4.9E-59 T 23-04-2016 DC74_RS21640 83dd76bdd6d0e7bca3e1bc37c41eda61 142 SUPERFAMILY SSF53927 1 140 8.03E-53 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 DC74_RS21640 83dd76bdd6d0e7bca3e1bc37c41eda61 142 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 47 84 - T 23-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 DC74_RS21640 83dd76bdd6d0e7bca3e1bc37c41eda61 142 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 142 45.868 T 23-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 DC74_RS21640 83dd76bdd6d0e7bca3e1bc37c41eda61 142 PANTHER PTHR11079 1 142 7.2E-47 T 23-04-2016 DC74_RS00915 37f7eaefc046df37456c0835435918ea 160 SMART SM00347 42 141 8.7E-4 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS00915 37f7eaefc046df37456c0835435918ea 160 Gene3D G3DSA:1.10.10.10 23 155 4.0E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00915 37f7eaefc046df37456c0835435918ea 160 SUPERFAMILY SSF46785 23 156 4.59E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00915 37f7eaefc046df37456c0835435918ea 160 Pfam PF12802 MarR family 49 105 3.7E-11 T 23-04-2016 DC74_RS34420 a0582ca8b7600a2743e5c729653900ea 184 Pfam PF07081 Protein of unknown function (DUF1349) 4 174 6.1E-22 T 23-04-2016 IPR009784 Protein of unknown function DUF1349 DC74_RS34420 a0582ca8b7600a2743e5c729653900ea 184 SUPERFAMILY SSF49899 2 174 4.75E-11 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS34420 a0582ca8b7600a2743e5c729653900ea 184 Gene3D G3DSA:2.60.120.200 2 132 7.7E-9 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain DC74_RS14095 953a6f6cad2ea7e1c04e8a7b8ffb4e6d 335 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 323 3.0E-48 T 23-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 DC74_RS14095 953a6f6cad2ea7e1c04e8a7b8ffb4e6d 335 PANTHER PTHR32196 1 332 4.5E-126 T 23-04-2016 DC74_RS14095 953a6f6cad2ea7e1c04e8a7b8ffb4e6d 335 PANTHER PTHR32196:SF34 1 332 4.5E-126 T 23-04-2016 DC74_RS09845 50a1694751da00fdced5a4df617f2a64 162 PANTHER PTHR23091:SF264 1 144 1.2E-25 T 23-04-2016 DC74_RS09845 50a1694751da00fdced5a4df617f2a64 162 Gene3D G3DSA:3.40.630.30 4 157 5.8E-27 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS09845 50a1694751da00fdced5a4df617f2a64 162 SUPERFAMILY SSF55729 3 143 3.21E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS09845 50a1694751da00fdced5a4df617f2a64 162 Pfam PF00583 Acetyltransferase (GNAT) family 62 137 2.0E-12 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS09845 50a1694751da00fdced5a4df617f2a64 162 PANTHER PTHR23091 1 144 1.2E-25 T 23-04-2016 DC74_RS06135 11937860178d7529fd83204347c77176 346 Pfam PF01497 Periplasmic binding protein 66 308 8.2E-24 T 23-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 DC74_RS06135 11937860178d7529fd83204347c77176 346 PANTHER PTHR30532:SF7 6 346 1.4E-56 T 23-04-2016 DC74_RS06135 11937860178d7529fd83204347c77176 346 Gene3D G3DSA:3.40.50.1980 173 310 1.6E-15 T 23-04-2016 DC74_RS06135 11937860178d7529fd83204347c77176 346 Gene3D G3DSA:3.40.50.1980 46 172 2.3E-27 T 23-04-2016 DC74_RS06135 11937860178d7529fd83204347c77176 346 PANTHER PTHR30532 6 346 1.4E-56 T 23-04-2016 DC74_RS06135 11937860178d7529fd83204347c77176 346 SUPERFAMILY SSF53807 48 331 8.24E-47 T 23-04-2016 DC74_RS00050 e3f98f3794cdc76714c473b4d472fc48 132 PANTHER PTHR35908 21 128 1.7E-13 T 23-04-2016 DC74_RS00050 e3f98f3794cdc76714c473b4d472fc48 132 Gene3D G3DSA:3.10.180.10 19 130 2.3E-12 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS00050 e3f98f3794cdc76714c473b4d472fc48 132 SUPERFAMILY SSF54593 20 131 1.05E-14 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS23275 d9f523cffc6ec3c37a8672a78997dd06 177 Gene3D G3DSA:3.30.1460.10 20 150 5.0E-15 T 23-04-2016 DC74_RS23275 d9f523cffc6ec3c37a8672a78997dd06 177 SUPERFAMILY SSF69635 19 142 1.26E-31 T 23-04-2016 DC74_RS23275 d9f523cffc6ec3c37a8672a78997dd06 177 Pfam PF10722 Putative bacterial sensory transduction regulator 20 139 3.6E-20 T 23-04-2016 IPR019660 Putative sensory transduction regulator YbjN DC74_RS37715 04e7721a59221b1fb85be190235ace93 227 PANTHER PTHR10204 8 193 4.1E-53 T 23-04-2016 DC74_RS37715 04e7721a59221b1fb85be190235ace93 227 SUPERFAMILY SSF52218 10 216 2.05E-55 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS37715 04e7721a59221b1fb85be190235ace93 227 Pfam PF02525 Flavodoxin-like fold 10 212 3.8E-47 T 23-04-2016 IPR003680 Flavodoxin-like fold DC74_RS37715 04e7721a59221b1fb85be190235ace93 227 PANTHER PTHR10204:SF46 8 193 4.1E-53 T 23-04-2016 DC74_RS37715 04e7721a59221b1fb85be190235ace93 227 Gene3D G3DSA:3.40.50.360 9 216 3.8E-58 T 23-04-2016 IPR029039 Flavoprotein-like domain DC74_RS21385 f8919d4b15de06fa5d5cc5c1ef4e4e3b 248 SUPERFAMILY SSF53474 2 245 3.62E-38 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS21385 f8919d4b15de06fa5d5cc5c1ef4e4e3b 248 Gene3D G3DSA:3.40.50.1820 3 243 1.7E-44 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS21385 f8919d4b15de06fa5d5cc5c1ef4e4e3b 248 Pfam PF01738 Dienelactone hydrolase family 16 243 5.7E-36 T 23-04-2016 IPR002925 Dienelactone hydrolase GO:0016787 DC74_RS21385 f8919d4b15de06fa5d5cc5c1ef4e4e3b 248 PANTHER PTHR17630 6 248 3.6E-77 T 23-04-2016 DC74_RS21385 f8919d4b15de06fa5d5cc5c1ef4e4e3b 248 PANTHER PTHR17630:SF51 6 248 3.6E-77 T 23-04-2016 DC74_RS31385 e7ca5ce221636e02b000908bb7df50c9 520 Pfam PF03606 C4-dicarboxylate anaerobic carrier 31 515 2.4E-102 T 23-04-2016 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 DC74_RS31385 e7ca5ce221636e02b000908bb7df50c9 520 PANTHER PTHR10283 335 509 4.4E-87 T 23-04-2016 DC74_RS31385 e7ca5ce221636e02b000908bb7df50c9 520 PANTHER PTHR10283 27 311 4.4E-87 T 23-04-2016 DC74_RS31385 e7ca5ce221636e02b000908bb7df50c9 520 PANTHER PTHR10283:SF90 335 509 4.4E-87 T 23-04-2016 DC74_RS31385 e7ca5ce221636e02b000908bb7df50c9 520 PANTHER PTHR10283:SF90 27 311 4.4E-87 T 23-04-2016 DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.1E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.1E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.1E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 PANTHER PTHR24322 12 134 3.4E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 PANTHER PTHR24322 150 182 3.4E-51 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 SUPERFAMILY SSF51735 6 256 7.55E-71 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 255 5.2E-54 T 23-04-2016 DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 Gene3D G3DSA:3.40.50.720 2 257 4.1E-72 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 3.0E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.0E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.0E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.0E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.0E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS01035 8ae9043a332472f5afe86f61d5902781 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 3.0E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS17660 991887b450a36420eb5b170c1ab6cb4c 282 SUPERFAMILY SSF103481 194 280 2.48E-9 T 23-04-2016 DC74_RS17660 991887b450a36420eb5b170c1ab6cb4c 282 PANTHER PTHR22911:SF61 9 281 8.0E-96 T 23-04-2016 DC74_RS17660 991887b450a36420eb5b170c1ab6cb4c 282 PANTHER PTHR22911 9 281 8.0E-96 T 23-04-2016 DC74_RS17660 991887b450a36420eb5b170c1ab6cb4c 282 Pfam PF00892 EamA-like transporter family 146 280 3.0E-8 T 23-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 DC74_RS17660 991887b450a36420eb5b170c1ab6cb4c 282 SUPERFAMILY SSF103481 42 135 2.22E-10 T 23-04-2016 DC74_RS07745 a930459c59914b179add6bf3c38d1457 438 SUPERFAMILY SSF103473 36 433 1.31E-39 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS07745 a930459c59914b179add6bf3c38d1457 438 Pfam PF07690 Major Facilitator Superfamily 70 292 4.6E-20 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS07745 a930459c59914b179add6bf3c38d1457 438 Gene3D G3DSA:1.20.1250.20 66 223 1.3E-17 T 23-04-2016 DC74_RS07745 a930459c59914b179add6bf3c38d1457 438 PANTHER PTHR23528 66 435 6.0E-29 T 23-04-2016 DC74_RS07745 a930459c59914b179add6bf3c38d1457 438 Gene3D G3DSA:1.20.1250.20 245 432 1.8E-18 T 23-04-2016 DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 PRINTS PR01806 Virulence factor MviN signature 364 385 1.9E-17 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 PRINTS PR01806 Virulence factor MviN signature 639 656 1.9E-17 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 PRINTS PR01806 Virulence factor MviN signature 260 276 1.9E-17 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 PRINTS PR01806 Virulence factor MviN signature 340 364 1.9E-17 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 PRINTS PR01806 Virulence factor MviN signature 241 260 1.9E-17 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 PRINTS PR01806 Virulence factor MviN signature 583 602 1.9E-17 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 211 739 3.5E-140 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 PANTHER PTHR11206:SF90 179 194 2.6E-12 T 23-04-2016 DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 PANTHER PTHR11206:SF90 438 673 2.6E-12 T 23-04-2016 DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 PANTHER PTHR11206:SF90 729 741 2.6E-12 T 23-04-2016 DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 PANTHER PTHR11206 179 194 2.6E-12 T 23-04-2016 DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 PANTHER PTHR11206 438 673 2.6E-12 T 23-04-2016 DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 PANTHER PTHR11206 729 741 2.6E-12 T 23-04-2016 DC74_RS20760 3c9c529d0a1cdc69055e3c301f879c70 748 Pfam PF03023 MviN-like protein 236 712 2.1E-121 T 23-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ DC74_RS24560 f30e92b8c7d9b2b83fdfe37099703690 192 SUPERFAMILY SSF81995 2 56 4.97E-7 T 23-04-2016 DC74_RS16060 d3e9835320f7790e1f394486e7b9b912 415 PANTHER PTHR41775 10 411 7.0E-89 T 23-04-2016 DC74_RS16060 d3e9835320f7790e1f394486e7b9b912 415 Gene3D G3DSA:3.40.390.10 214 270 2.4E-5 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 DC74_RS16060 d3e9835320f7790e1f394486e7b9b912 415 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 78 342 4.1E-57 T 23-04-2016 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 DC74_RS21105 48dbdce4cc9c6b8039a97b1c41d8c4a2 258 Pfam PF12679 ABC-2 family transporter protein 77 190 7.0E-10 T 23-04-2016 IPR032688 ABC-2 family transporter protein GO:0006810 DC74_RS13375 e4c29194b55e5d6febd6c23325fa9f7c 308 PANTHER PTHR30193 2 308 2.2E-61 T 23-04-2016 DC74_RS13375 e4c29194b55e5d6febd6c23325fa9f7c 308 PANTHER PTHR30193:SF2 2 308 2.2E-61 T 23-04-2016 DC74_RS13375 e4c29194b55e5d6febd6c23325fa9f7c 308 Gene3D G3DSA:1.10.3720.10 16 292 1.1E-45 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS13375 e4c29194b55e5d6febd6c23325fa9f7c 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 244 1.3E-10 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS13375 e4c29194b55e5d6febd6c23325fa9f7c 308 SUPERFAMILY SSF161098 68 291 2.35E-44 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS08805 52a14472f88bfd4fcf438a70fb1ac462 326 PANTHER PTHR10819 14 325 5.0E-77 T 23-04-2016 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 DC74_RS08805 52a14472f88bfd4fcf438a70fb1ac462 326 SUPERFAMILY SSF51556 20 323 8.29E-62 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS08805 52a14472f88bfd4fcf438a70fb1ac462 326 Gene3D G3DSA:3.20.20.140 20 323 5.9E-83 T 23-04-2016 DC74_RS08805 52a14472f88bfd4fcf438a70fb1ac462 326 Pfam PF02126 Phosphotriesterase family 30 321 1.2E-33 T 23-04-2016 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 DC74_RS08805 52a14472f88bfd4fcf438a70fb1ac462 326 PIRSF PIRSF016839 19 326 6.3E-94 T 23-04-2016 DC74_RS24975 b7ad309fc1d978b4fe593a7f0ce581d6 70 Pfam PF04024 PspC domain 5 59 3.4E-17 T 23-04-2016 IPR007168 Phage shock protein, PspC, N-terminal DC74_RS24975 b7ad309fc1d978b4fe593a7f0ce581d6 70 PANTHER PTHR33885 5 66 1.3E-18 T 23-04-2016 DC74_RS03025 12a81c51addbac92e31c8dcb737100e5 89 SUPERFAMILY SSF47336 2 76 3.53E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS03025 12a81c51addbac92e31c8dcb737100e5 89 Gene3D G3DSA:1.10.1200.10 2 76 7.8E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS03025 12a81c51addbac92e31c8dcb737100e5 89 Pfam PF00550 Phosphopantetheine attachment site 8 71 4.9E-8 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS11595 e1d2d5296962485a95e1153939afc7c3 356 PANTHER PTHR22893:SF14 5 356 8.1E-143 T 23-04-2016 DC74_RS11595 e1d2d5296962485a95e1153939afc7c3 356 SUPERFAMILY SSF51395 4 354 7.59E-112 T 23-04-2016 DC74_RS11595 e1d2d5296962485a95e1153939afc7c3 356 Gene3D G3DSA:3.20.20.70 5 352 3.1E-119 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS11595 e1d2d5296962485a95e1153939afc7c3 356 PANTHER PTHR22893 5 356 8.1E-143 T 23-04-2016 DC74_RS11595 e1d2d5296962485a95e1153939afc7c3 356 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 330 4.4E-76 T 23-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 DC74_RS37230 1a9851ace9a4084b4c8ef33369932a99 245 Pfam PF03756 A-factor biosynthesis hotdog domain 1 94 1.2E-6 T 23-04-2016 IPR005509 A-factor biosynthesis hotdog domain DC74_RS37230 1a9851ace9a4084b4c8ef33369932a99 245 Pfam PF03756 A-factor biosynthesis hotdog domain 129 238 9.1E-14 T 23-04-2016 IPR005509 A-factor biosynthesis hotdog domain DC74_RS21890 3074f090b59e4e04a490e5da9219aa13 149 Pfam PF07681 DoxX 53 110 3.9E-6 T 23-04-2016 IPR032808 DoxX family DC74_RS19055 2552d836302bcaa5ab362592ee6bbde3 281 Gene3D G3DSA:3.40.30.10 85 172 3.3E-10 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS19055 2552d836302bcaa5ab362592ee6bbde3 281 PANTHER PTHR10371 7 175 2.0E-63 T 23-04-2016 DC74_RS19055 2552d836302bcaa5ab362592ee6bbde3 281 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 22 164 4.9E-48 T 23-04-2016 DC74_RS19055 2552d836302bcaa5ab362592ee6bbde3 281 SUPERFAMILY SSF52833 17 174 5.48E-47 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS09005 994325a5acd3a0ae6ab55d7506537925 446 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 266 287 - T 23-04-2016 IPR021115 Pyridoxal-phosphate binding site GO:0016831 DC74_RS09005 994325a5acd3a0ae6ab55d7506537925 446 Gene3D G3DSA:3.40.640.10 70 339 1.7E-80 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS09005 994325a5acd3a0ae6ab55d7506537925 446 PANTHER PTHR11999 36 434 9.4E-74 T 23-04-2016 DC74_RS09005 994325a5acd3a0ae6ab55d7506537925 446 SUPERFAMILY SSF53383 19 441 5.2E-104 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS09005 994325a5acd3a0ae6ab55d7506537925 446 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 30 383 3.0E-54 T 23-04-2016 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 DC74_RS09005 994325a5acd3a0ae6ab55d7506537925 446 Gene3D G3DSA:3.90.1150.10 340 441 3.4E-26 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS23665 b6bf54a92feec37ae87db9545fd96774 328 Gene3D G3DSA:3.40.50.1980 49 164 2.3E-32 T 23-04-2016 DC74_RS23665 b6bf54a92feec37ae87db9545fd96774 328 PANTHER PTHR30532 49 328 9.2E-65 T 23-04-2016 DC74_RS23665 b6bf54a92feec37ae87db9545fd96774 328 PANTHER PTHR30532:SF3 49 328 9.2E-65 T 23-04-2016 DC74_RS23665 b6bf54a92feec37ae87db9545fd96774 328 Pfam PF01497 Periplasmic binding protein 65 303 3.3E-24 T 23-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 DC74_RS23665 b6bf54a92feec37ae87db9545fd96774 328 SUPERFAMILY SSF53807 49 321 2.32E-54 T 23-04-2016 DC74_RS23665 b6bf54a92feec37ae87db9545fd96774 328 Gene3D G3DSA:3.40.50.1980 165 326 1.3E-28 T 23-04-2016 DC74_RS05005 dcf4e890494a398aca303d87bf7ddbce 502 SUPERFAMILY SSF103378 18 481 6.28E-123 T 23-04-2016 IPR005656 MmgE/PrpD GO:0016829 DC74_RS05005 dcf4e890494a398aca303d87bf7ddbce 502 PANTHER PTHR16943 1 495 5.9E-127 T 23-04-2016 IPR005656 MmgE/PrpD GO:0016829 DC74_RS05005 dcf4e890494a398aca303d87bf7ddbce 502 Pfam PF03972 MmgE/PrpD family 27 471 8.3E-127 T 23-04-2016 IPR005656 MmgE/PrpD GO:0016829 DC74_RS05005 dcf4e890494a398aca303d87bf7ddbce 502 PANTHER PTHR16943:SF19 1 495 5.9E-127 T 23-04-2016 DC74_RS05005 dcf4e890494a398aca303d87bf7ddbce 502 Gene3D G3DSA:3.30.1330.120 283 422 9.2E-47 T 23-04-2016 DC74_RS04450 bc420f10e50d7805b1d37678aefb0c12 310 PANTHER PTHR12121:SF36 45 310 3.0E-58 T 23-04-2016 DC74_RS04450 bc420f10e50d7805b1d37678aefb0c12 310 Gene3D G3DSA:3.60.10.10 49 308 1.1E-15 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS04450 bc420f10e50d7805b1d37678aefb0c12 310 SUPERFAMILY SSF56219 46 306 2.62E-37 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS04450 bc420f10e50d7805b1d37678aefb0c12 310 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 52 301 1.1E-16 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase DC74_RS04450 bc420f10e50d7805b1d37678aefb0c12 310 PANTHER PTHR12121 45 310 3.0E-58 T 23-04-2016 DC74_RS19030 d26405bad3ae4d49d156eb866d5fc42d 283 PANTHER PTHR33269:SF1 6 203 2.0E-75 T 23-04-2016 DC74_RS19030 d26405bad3ae4d49d156eb866d5fc42d 283 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 26 171 2.2E-30 T 23-04-2016 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 DC74_RS19030 d26405bad3ae4d49d156eb866d5fc42d 283 PANTHER PTHR33269 6 203 2.0E-75 T 23-04-2016 DC74_RS08895 be35bbc8d9ad2fca48aee970c5a7433a 171 Gene3D G3DSA:1.20.120.450 1 170 2.1E-46 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS08895 be35bbc8d9ad2fca48aee970c5a7433a 171 Pfam PF04978 Protein of unknown function (DUF664) 23 167 7.8E-42 T 23-04-2016 IPR007061 Protein of unknown function DUF664 DC74_RS08895 be35bbc8d9ad2fca48aee970c5a7433a 171 SUPERFAMILY SSF109854 2 166 2.29E-41 T 23-04-2016 DC74_RS34955 946f808d61c7c9d680e3822d84d54117 405 Pfam PF01757 Acyltransferase family 28 365 2.1E-18 T 23-04-2016 IPR002656 Acyltransferase 3 GO:0016747 DC74_RS05165 7357b2f7e1e36a756946106a2c691dbe 217 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 1 39 6.5E-10 T 23-04-2016 IPR010627 Peptidase A24A, N-terminal KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS05165 7357b2f7e1e36a756946106a2c691dbe 217 PANTHER PTHR30487:SF0 1 208 5.7E-38 T 23-04-2016 DC74_RS05165 7357b2f7e1e36a756946106a2c691dbe 217 PANTHER PTHR30487 1 208 5.7E-38 T 23-04-2016 DC74_RS05165 7357b2f7e1e36a756946106a2c691dbe 217 Pfam PF01478 Type IV leader peptidase family 49 161 3.2E-8 T 23-04-2016 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 DC74_RS25620 25d09939e031504448ecf8f374646c6e 169 Pfam PF14030 Protein of unknown function (DUF4245) 1 164 2.7E-45 T 23-04-2016 IPR025339 Protein of unknown function DUF4245 DC74_RS21285 b1e12fb9ff6b41acd6c2b42144b4206b 236 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 25 208 5.9E-19 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal DC74_RS21285 b1e12fb9ff6b41acd6c2b42144b4206b 236 SMART SM00943 25 210 2.8E-20 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal DC74_RS18885 3a5260f79449e350ea407b7cc2ec4896 288 Hamap MF_00188 Protease HtpX [htpX]. 7 282 27.972 T 23-04-2016 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 DC74_RS18885 3a5260f79449e350ea407b7cc2ec4896 288 PANTHER PTHR10120 265 288 3.9E-103 T 23-04-2016 DC74_RS18885 3a5260f79449e350ea407b7cc2ec4896 288 Pfam PF01435 Peptidase family M48 68 282 1.9E-35 T 23-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DC74_RS18885 3a5260f79449e350ea407b7cc2ec4896 288 PANTHER PTHR10120:SF19 265 288 3.9E-103 T 23-04-2016 DC74_RS18885 3a5260f79449e350ea407b7cc2ec4896 288 PANTHER PTHR10120 6 246 3.9E-103 T 23-04-2016 DC74_RS18885 3a5260f79449e350ea407b7cc2ec4896 288 Gene3D G3DSA:3.30.2010.10 59 149 6.2E-31 T 23-04-2016 DC74_RS18885 3a5260f79449e350ea407b7cc2ec4896 288 PANTHER PTHR10120:SF19 6 246 3.9E-103 T 23-04-2016 DC74_RS04240 6022ed4de64e9c55664857d1e7bf59de 87 PANTHER PTHR21666 1 79 5.3E-17 T 23-04-2016 DC74_RS04240 6022ed4de64e9c55664857d1e7bf59de 87 SUPERFAMILY SSF54001 1 83 5.4E-22 T 23-04-2016 DC74_RS04240 6022ed4de64e9c55664857d1e7bf59de 87 Pfam PF00877 NlpC/P60 family 1 81 6.4E-17 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS04240 6022ed4de64e9c55664857d1e7bf59de 87 Gene3D G3DSA:3.90.1720.10 1 83 8.3E-24 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS08575 312100fdc6b0550680bff4259a2629be 142 PANTHER PTHR35176 20 139 4.1E-31 T 23-04-2016 DC74_RS08575 312100fdc6b0550680bff4259a2629be 142 Gene3D G3DSA:2.30.110.10 14 138 4.8E-34 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS08575 312100fdc6b0550680bff4259a2629be 142 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 19 134 2.0E-28 T 23-04-2016 IPR019920 F420-binding domain, putative DC74_RS08575 312100fdc6b0550680bff4259a2629be 142 SUPERFAMILY SSF50475 17 136 4.44E-29 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS08575 312100fdc6b0550680bff4259a2629be 142 PANTHER PTHR35176:SF1 20 139 4.1E-31 T 23-04-2016 DC74_RS08575 312100fdc6b0550680bff4259a2629be 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 16 101 3.0E-11 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS12890 e11a4495494c744c37fccd5df7156541 347 Pfam PF00355 Rieske [2Fe-2S] domain 233 319 8.3E-11 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS12890 e11a4495494c744c37fccd5df7156541 347 SUPERFAMILY SSF50022 165 345 4.98E-29 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS12890 e11a4495494c744c37fccd5df7156541 347 Gene3D G3DSA:2.102.10.10 204 346 1.8E-37 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS12890 e11a4495494c744c37fccd5df7156541 347 PRINTS PR00162 Rieske 2Fe-2S subunit signature 305 317 8.6E-6 T 23-04-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 DC74_RS12890 e11a4495494c744c37fccd5df7156541 347 PRINTS PR00162 Rieske 2Fe-2S subunit signature 269 280 8.6E-6 T 23-04-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 DC74_RS12890 e11a4495494c744c37fccd5df7156541 347 PRINTS PR00162 Rieske 2Fe-2S subunit signature 291 303 8.6E-6 T 23-04-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 DC74_RS12440 fcdd7a0ed5abb5e514c929232ebd9a0a 439 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 38 429 6.1E-77 T 23-04-2016 IPR018721 Protein of unknown function DUF2252 DC74_RS12440 fcdd7a0ed5abb5e514c929232ebd9a0a 439 PANTHER PTHR39441 37 439 1.4E-98 T 23-04-2016 DC74_RS02815 e074c294200c37d4c01aba3f9aedbbe2 111 Pfam PF09851 Short C-terminal domain 70 96 2.8E-8 T 23-04-2016 IPR018649 SHOCT domain DC74_RS24495 8d3ff7282d952bedf8bda335a39cb721 682 SMART SM00382 467 599 1.3E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS24495 8d3ff7282d952bedf8bda335a39cb721 682 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 472 596 8.5E-22 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 DC74_RS24495 8d3ff7282d952bedf8bda335a39cb721 682 SUPERFAMILY SSF52540 425 638 1.14E-36 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24495 8d3ff7282d952bedf8bda335a39cb721 682 PANTHER PTHR23073:SF24 472 649 9.4E-32 T 23-04-2016 DC74_RS24495 8d3ff7282d952bedf8bda335a39cb721 682 PANTHER PTHR23073 472 649 9.4E-32 T 23-04-2016 DC74_RS24495 8d3ff7282d952bedf8bda335a39cb721 682 Gene3D G3DSA:3.40.50.300 425 612 5.6E-34 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 SUPERFAMILY SSF52743 149 330 4.32E-71 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 SUPERFAMILY SSF52743 357 496 4.32E-71 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 PRINTS PR00723 Subtilisin serine protease family (S8) signature 426 442 1.42E-19 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 PRINTS PR00723 Subtilisin serine protease family (S8) signature 169 188 1.42E-19 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 PRINTS PR00723 Subtilisin serine protease family (S8) signature 218 231 1.42E-19 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 222 232 - T 23-04-2016 IPR022398 Peptidase S8, subtilisin, His-active site DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 427 437 - T 23-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 PANTHER PTHR10795:SF419 353 496 3.1E-60 T 23-04-2016 DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 PANTHER PTHR10795:SF419 142 329 3.1E-60 T 23-04-2016 DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 PANTHER PTHR10795:SF419 52 104 3.1E-60 T 23-04-2016 DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 174 185 - T 23-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 Gene3D G3DSA:3.40.50.200 141 496 1.4E-76 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 PANTHER PTHR10795 353 496 3.1E-60 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 PANTHER PTHR10795 142 329 3.1E-60 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 PANTHER PTHR10795 52 104 3.1E-60 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related DC74_RS11365 d5f3d39139fc12f38cb46d656fad0839 496 Pfam PF00082 Subtilase family 170 476 3.7E-40 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DC74_RS34910 9ef9ea6068fe0b241567e767bf4e91c8 342 Gene3D G3DSA:3.40.50.1820 70 335 2.5E-32 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34910 9ef9ea6068fe0b241567e767bf4e91c8 342 SUPERFAMILY SSF53474 76 320 3.65E-24 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34910 9ef9ea6068fe0b241567e767bf4e91c8 342 Pfam PF00756 Putative esterase 90 282 3.5E-13 T 23-04-2016 IPR000801 Putative esterase DC74_RS20125 849361d14208b17ea9423a072897a6d4 444 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 85 247 6.8E-47 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS20125 849361d14208b17ea9423a072897a6d4 444 PANTHER PTHR33392:SF7 2 441 4.4E-110 T 23-04-2016 DC74_RS20125 849361d14208b17ea9423a072897a6d4 444 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 356 439 2.0E-15 T 23-04-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain DC74_RS20125 849361d14208b17ea9423a072897a6d4 444 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 84 247 3.3E-42 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain DC74_RS20125 849361d14208b17ea9423a072897a6d4 444 PANTHER PTHR33392 2 441 4.4E-110 T 23-04-2016 DC74_RS31375 308018176fc866c2c70584261af97858 192 Gene3D G3DSA:1.10.357.10 2 183 1.1E-27 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS31375 308018176fc866c2c70584261af97858 192 PANTHER PTHR30055:SF2 3 179 1.1E-16 T 23-04-2016 DC74_RS31375 308018176fc866c2c70584261af97858 192 PANTHER PTHR30055 3 179 1.1E-16 T 23-04-2016 DC74_RS31375 308018176fc866c2c70584261af97858 192 SUPERFAMILY SSF46689 3 73 5.13E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS31375 308018176fc866c2c70584261af97858 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 52 5.5E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS13655 37ef183e66ad9ec20aeac68896658a8a 77 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 9 62 4.4E-10 T 23-04-2016 DC74_RS13655 37ef183e66ad9ec20aeac68896658a8a 77 PRINTS PR00352 3Fe-4S ferredoxin signature 9 20 4.2E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS13655 37ef183e66ad9ec20aeac68896658a8a 77 PRINTS PR00352 3Fe-4S ferredoxin signature 20 30 4.2E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS13655 37ef183e66ad9ec20aeac68896658a8a 77 PRINTS PR00352 3Fe-4S ferredoxin signature 49 61 4.2E-6 T 23-04-2016 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 DC74_RS13655 37ef183e66ad9ec20aeac68896658a8a 77 SUPERFAMILY SSF54862 6 63 5.12E-10 T 23-04-2016 DC74_RS13655 37ef183e66ad9ec20aeac68896658a8a 77 Gene3D G3DSA:3.30.70.20 5 65 5.3E-14 T 23-04-2016 DC74_RS20505 bda850f26566a79675d4260ceafacd51 489 PANTHER PTHR39441 393 488 1.4E-130 T 23-04-2016 DC74_RS20505 bda850f26566a79675d4260ceafacd51 489 PANTHER PTHR39441 3 365 1.4E-130 T 23-04-2016 DC74_RS20505 bda850f26566a79675d4260ceafacd51 489 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 59 476 1.8E-131 T 23-04-2016 IPR018721 Protein of unknown function DUF2252 DC74_RS15230 a1f9ba4b6fdb1acc30073585fe4b9c4e 267 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 3 216 8.1E-56 T 23-04-2016 IPR018768 Domain of unknown function DUF2344 DC74_RS15230 a1f9ba4b6fdb1acc30073585fe4b9c4e 267 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 3 191 2.4E-50 T 23-04-2016 IPR018768 Domain of unknown function DUF2344 DC74_RS35545 6024b43194b8a280a00355094c2c3acc 123 Gene3D G3DSA:1.10.10.10 31 117 1.1E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35545 6024b43194b8a280a00355094c2c3acc 123 PANTHER PTHR37318 24 123 1.1E-20 T 23-04-2016 DC74_RS35545 6024b43194b8a280a00355094c2c3acc 123 SUPERFAMILY SSF46785 33 117 1.29E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS35545 6024b43194b8a280a00355094c2c3acc 123 Pfam PF13601 Winged helix DNA-binding domain 39 117 3.0E-25 T 23-04-2016 IPR027395 Winged helix DNA-binding domain DC74_RS04930 0fcc3dbaa3fd1dee707dd546da50ce0d 455 PANTHER PTHR30365 1 447 3.2E-158 T 23-04-2016 DC74_RS04930 0fcc3dbaa3fd1dee707dd546da50ce0d 455 PIRSF PIRSF006446 2 450 6.0E-145 T 23-04-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 DC74_RS04930 0fcc3dbaa3fd1dee707dd546da50ce0d 455 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 437 1.0E-139 T 23-04-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 DC74_RS04930 0fcc3dbaa3fd1dee707dd546da50ce0d 455 PANTHER PTHR30365:SF0 1 447 3.2E-158 T 23-04-2016 DC74_RS11405 5c094bc7af0a8e8dad655f30f92a540a 210 PANTHER PTHR30055 3 100 1.9E-13 T 23-04-2016 DC74_RS11405 5c094bc7af0a8e8dad655f30f92a540a 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 1.6E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS11405 5c094bc7af0a8e8dad655f30f92a540a 210 Gene3D G3DSA:1.10.357.10 3 202 9.6E-35 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS11405 5c094bc7af0a8e8dad655f30f92a540a 210 SUPERFAMILY SSF46689 4 67 1.15E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS11405 5c094bc7af0a8e8dad655f30f92a540a 210 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 73 202 2.5E-8 T 23-04-2016 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 DC74_RS11405 5c094bc7af0a8e8dad655f30f92a540a 210 SUPERFAMILY SSF48498 76 202 2.31E-12 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS11405 5c094bc7af0a8e8dad655f30f92a540a 210 PANTHER PTHR30055:SF36 3 100 1.9E-13 T 23-04-2016 DC74_RS11405 5c094bc7af0a8e8dad655f30f92a540a 210 PRINTS PR00400 Tetracycline repressor protein signature 188 202 7.1E-9 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS11405 5c094bc7af0a8e8dad655f30f92a540a 210 PRINTS PR00400 Tetracycline repressor protein signature 131 150 7.1E-9 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS11405 5c094bc7af0a8e8dad655f30f92a540a 210 PRINTS PR00400 Tetracycline repressor protein signature 23 46 7.1E-9 T 23-04-2016 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 DC74_RS31125 b15613a38c23db3954c2b684e71d91f5 367 Pfam PF10935 Protein of unknown function (DUF2637) 69 221 7.6E-23 T 23-04-2016 IPR021235 Protein of unknown function DUF2637 DC74_RS15265 4140ee0c8477008c31262e437dd0fa87 232 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 6 158 1.0E-17 T 23-04-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 DC74_RS15265 4140ee0c8477008c31262e437dd0fa87 232 Pfam PF04093 rod shape-determining protein MreD 3 93 1.3E-5 T 23-04-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 DC74_RS38095 b457dfda5e616d6c4e9246bf1738b81b 298 PANTHER PTHR14194 1 293 9.1E-124 T 23-04-2016 DC74_RS38095 b457dfda5e616d6c4e9246bf1738b81b 298 SUPERFAMILY SSF51735 2 266 7.18E-41 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38095 b457dfda5e616d6c4e9246bf1738b81b 298 Pfam PF13460 NAD(P)H-binding 8 195 2.1E-17 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS38095 b457dfda5e616d6c4e9246bf1738b81b 298 PANTHER PTHR14194:SF57 1 293 9.1E-124 T 23-04-2016 DC74_RS38095 b457dfda5e616d6c4e9246bf1738b81b 298 Gene3D G3DSA:3.40.50.720 2 231 2.2E-28 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10075 186683e25aa5c9334c1ff13d54c45406 445 Gene3D G3DSA:1.25.40.10 212 418 1.1E-8 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS10075 186683e25aa5c9334c1ff13d54c45406 445 SUPERFAMILY SSF48452 214 365 1.55E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS25285 9d8c4df3da01c69527fca110c51e05de 484 Gene3D G3DSA:3.10.580.10 259 363 1.5E-12 T 23-04-2016 DC74_RS25285 9d8c4df3da01c69527fca110c51e05de 484 Pfam PF00571 CBS domain 259 306 0.0027 T 23-04-2016 IPR000644 CBS domain DC74_RS25285 9d8c4df3da01c69527fca110c51e05de 484 SUPERFAMILY SSF54631 250 364 2.53E-14 T 23-04-2016 DC74_RS10045 c6878b846262fb57295a5c298e6f016c 100 PANTHER PTHR30007 11 65 2.7E-13 T 23-04-2016 DC74_RS10045 c6878b846262fb57295a5c298e6f016c 100 PANTHER PTHR30007:SF18 11 65 2.7E-13 T 23-04-2016 DC74_RS25565 921f639734175f789d4aab1193dd0ea9 227 Gene3D G3DSA:3.40.50.150 22 200 8.2E-33 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS25565 921f639734175f789d4aab1193dd0ea9 227 SUPERFAMILY SSF53335 25 205 2.23E-30 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS25565 921f639734175f789d4aab1193dd0ea9 227 Pfam PF13649 Methyltransferase domain 60 155 6.3E-16 T 23-04-2016 DC74_RS25565 921f639734175f789d4aab1193dd0ea9 227 PANTHER PTHR10108 49 200 6.8E-19 T 23-04-2016 DC74_RS34120 9b9f53db1de6f877089c26c4263af415 290 Pfam PF11611 Domain of unknown function (DUF4352) 192 277 4.3E-7 T 23-04-2016 IPR029051 Domain of unknown function DUF4352 DC74_RS34120 9b9f53db1de6f877089c26c4263af415 290 Gene3D G3DSA:2.60.40.1240 171 279 2.1E-9 T 23-04-2016 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain DC74_RS33545 a51b8ced58b6ef22c38cb9c2c2a7e150 362 SMART SM00028 165 198 23.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS33545 a51b8ced58b6ef22c38cb9c2c2a7e150 362 SMART SM00028 205 238 110.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS33545 a51b8ced58b6ef22c38cb9c2c2a7e150 362 SMART SM00028 245 278 16.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 DC74_RS33545 a51b8ced58b6ef22c38cb9c2c2a7e150 362 PANTHER PTHR10098:SF104 13 329 9.6E-15 T 23-04-2016 DC74_RS33545 a51b8ced58b6ef22c38cb9c2c2a7e150 362 Gene3D G3DSA:1.25.40.10 9 106 7.9E-5 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS33545 a51b8ced58b6ef22c38cb9c2c2a7e150 362 Gene3D G3DSA:1.25.40.10 107 301 2.3E-21 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS33545 a51b8ced58b6ef22c38cb9c2c2a7e150 362 SUPERFAMILY SSF48452 67 288 4.93E-23 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS33545 a51b8ced58b6ef22c38cb9c2c2a7e150 362 PANTHER PTHR10098 13 329 9.6E-15 T 23-04-2016 DC74_RS33545 a51b8ced58b6ef22c38cb9c2c2a7e150 362 Pfam PF13424 Tetratricopeptide repeat 167 236 7.3E-10 T 23-04-2016 DC74_RS05625 0ab4c0901c96337bb067a8acf4646809 349 SUPERFAMILY SSF55961 118 347 1.46E-15 T 23-04-2016 DC74_RS05625 0ab4c0901c96337bb067a8acf4646809 349 SUPERFAMILY SSF50022 18 127 2.49E-31 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS05625 0ab4c0901c96337bb067a8acf4646809 349 PANTHER PTHR21266 18 341 7.6E-38 T 23-04-2016 DC74_RS05625 0ab4c0901c96337bb067a8acf4646809 349 Gene3D G3DSA:2.102.10.10 21 132 1.8E-29 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS05625 0ab4c0901c96337bb067a8acf4646809 349 Pfam PF00355 Rieske [2Fe-2S] domain 21 104 3.7E-16 T 23-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DC74_RS26895 d1d0b216dd4e4c87b6541c3937d7aebb 220 Gene3D G3DSA:3.40.50.270 19 132 8.2E-30 T 23-04-2016 DC74_RS26895 d1d0b216dd4e4c87b6541c3937d7aebb 220 Gene3D G3DSA:3.40.50.270 176 213 8.2E-30 T 23-04-2016 DC74_RS26895 d1d0b216dd4e4c87b6541c3937d7aebb 220 SUPERFAMILY SSF52788 19 141 3.79E-22 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS26895 d1d0b216dd4e4c87b6541c3937d7aebb 220 SUPERFAMILY SSF52788 183 211 3.79E-22 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS26895 d1d0b216dd4e4c87b6541c3937d7aebb 220 SMART SM00226 19 212 5.1E-6 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS26895 d1d0b216dd4e4c87b6541c3937d7aebb 220 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 21 142 4.0E-14 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily DC74_RS26895 d1d0b216dd4e4c87b6541c3937d7aebb 220 PANTHER PTHR11717:SF14 20 118 3.3E-15 T 23-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 DC74_RS26895 d1d0b216dd4e4c87b6541c3937d7aebb 220 PANTHER PTHR11717:SF14 180 214 3.3E-15 T 23-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 DC74_RS26895 d1d0b216dd4e4c87b6541c3937d7aebb 220 PANTHER PTHR11717 20 118 3.3E-15 T 23-04-2016 DC74_RS26895 d1d0b216dd4e4c87b6541c3937d7aebb 220 PANTHER PTHR11717 180 214 3.3E-15 T 23-04-2016 DC74_RS07665 0f979b713fe55da0eabf8e11fc906874 234 Pfam PF13796 Putative sensor 43 226 2.1E-6 T 23-04-2016 IPR025828 Putative sensor domain DC74_RS35605 6552745925aa8aa7380c44f0331b00d3 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 5.9E-51 T 23-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35605 6552745925aa8aa7380c44f0331b00d3 100 PIRSF PIRSF001223 1 100 5.8E-53 T 23-04-2016 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35605 6552745925aa8aa7380c44f0331b00d3 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 35.109 T 23-04-2016 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35605 6552745925aa8aa7380c44f0331b00d3 100 PANTHER PTHR33569 2 99 6.5E-45 T 23-04-2016 DC74_RS35605 6552745925aa8aa7380c44f0331b00d3 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 2.0E-43 T 23-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35605 6552745925aa8aa7380c44f0331b00d3 100 PANTHER PTHR33569:SF1 2 99 6.5E-45 T 23-04-2016 DC74_RS35605 6552745925aa8aa7380c44f0331b00d3 100 Pfam PF00547 Urease, gamma subunit 1 99 1.1E-47 T 23-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35605 6552745925aa8aa7380c44f0331b00d3 100 Gene3D G3DSA:3.30.280.10 1 99 1.6E-49 T 23-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS35605 6552745925aa8aa7380c44f0331b00d3 100 SUPERFAMILY SSF54111 1 99 3.53E-46 T 23-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 DC74_RS19890 186dbff75952dfa3ffa84abadfba50b9 281 SUPERFAMILY SSF74650 12 262 2.51E-42 T 23-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 DC74_RS19890 186dbff75952dfa3ffa84abadfba50b9 281 PANTHER PTHR10091:SF5 21 199 1.8E-41 T 23-04-2016 DC74_RS19890 186dbff75952dfa3ffa84abadfba50b9 281 Pfam PF01263 Aldose 1-epimerase 29 240 1.6E-20 T 23-04-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 DC74_RS19890 186dbff75952dfa3ffa84abadfba50b9 281 PANTHER PTHR10091 21 199 1.8E-41 T 23-04-2016 DC74_RS19890 186dbff75952dfa3ffa84abadfba50b9 281 Gene3D G3DSA:2.70.98.10 16 258 1.8E-17 T 23-04-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 DC74_RS34125 66416a7e28cad6f8b5375ac4b31cab0b 239 SMART SM00327 36 214 1.8E-5 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS34125 66416a7e28cad6f8b5375ac4b31cab0b 239 Gene3D G3DSA:3.40.50.410 37 177 3.0E-7 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS34125 66416a7e28cad6f8b5375ac4b31cab0b 239 SUPERFAMILY SSF53300 37 190 3.41E-16 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS34125 66416a7e28cad6f8b5375ac4b31cab0b 239 Pfam PF10138 vWA found in TerF C terminus 36 238 1.7E-63 T 23-04-2016 IPR019303 vWA found in TerF C terminus DC74_RS00265 48e334638f996be9cc70bf14c6072357 131 SUPERFAMILY SSF51182 2 113 3.66E-22 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS00265 48e334638f996be9cc70bf14c6072357 131 PANTHER PTHR36114 1 123 6.0E-27 T 23-04-2016 DC74_RS00265 48e334638f996be9cc70bf14c6072357 131 Gene3D G3DSA:2.60.120.10 3 110 2.8E-32 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS00265 48e334638f996be9cc70bf14c6072357 131 Pfam PF07883 Cupin domain 39 97 2.6E-10 T 23-04-2016 IPR013096 Cupin 2, conserved barrel DC74_RS17450 022715b15547185f4c1eae297a8b6776 574 Gene3D G3DSA:1.20.1250.20 30 210 9.1E-32 T 23-04-2016 DC74_RS17450 022715b15547185f4c1eae297a8b6776 574 Gene3D G3DSA:1.20.1250.20 286 443 6.8E-20 T 23-04-2016 DC74_RS17450 022715b15547185f4c1eae297a8b6776 574 Gene3D G3DSA:1.20.1250.20 491 517 6.8E-20 T 23-04-2016 DC74_RS17450 022715b15547185f4c1eae297a8b6776 574 Pfam PF07690 Major Facilitator Superfamily 36 433 4.4E-47 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS17450 022715b15547185f4c1eae297a8b6776 574 SUPERFAMILY SSF103473 490 518 4.19E-65 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS17450 022715b15547185f4c1eae297a8b6776 574 SUPERFAMILY SSF103473 29 220 4.19E-65 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS17450 022715b15547185f4c1eae297a8b6776 574 SUPERFAMILY SSF103473 272 442 4.19E-65 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS17450 022715b15547185f4c1eae297a8b6776 574 PANTHER PTHR23501:SF73 32 517 2.2E-119 T 23-04-2016 DC74_RS17450 022715b15547185f4c1eae297a8b6776 574 PANTHER PTHR23501 32 517 2.2E-119 T 23-04-2016 DC74_RS16480 99d174a8968290f7a58166cd6079adfa 322 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 7 318 8.3E-121 T 23-04-2016 IPR026449 ATP-grasp ribosomal peptide maturase, SAV_5884 family DC74_RS16480 99d174a8968290f7a58166cd6079adfa 322 SUPERFAMILY SSF56059 135 319 7.6E-23 T 23-04-2016 DC74_RS16480 99d174a8968290f7a58166cd6079adfa 322 PANTHER PTHR21621 113 318 9.3E-16 T 23-04-2016 DC74_RS16480 99d174a8968290f7a58166cd6079adfa 322 Gene3D G3DSA:3.30.470.20 204 315 4.6E-5 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS34115 79e1141023537829f9b74d5bbf1ee5f0 300 Gene3D G3DSA:3.40.710.10 51 267 3.3E-26 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS34115 79e1141023537829f9b74d5bbf1ee5f0 300 Pfam PF13354 Beta-lactamase enzyme family 107 244 3.2E-10 T 23-04-2016 DC74_RS34115 79e1141023537829f9b74d5bbf1ee5f0 300 SUPERFAMILY SSF56601 40 267 3.59E-27 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS19600 950c07470240dabc6db8d58af3d2683b 379 SMART SM00331 149 375 2.1E-28 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS19600 950c07470240dabc6db8d58af3d2683b 379 PANTHER PTHR21021 127 375 3.0E-26 T 23-04-2016 DC74_RS19600 950c07470240dabc6db8d58af3d2683b 379 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 178 375 1.2E-39 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS19600 950c07470240dabc6db8d58af3d2683b 379 SUPERFAMILY SSF81606 166 374 4.97E-6 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 DC74_RS21680 cbaa0b67ca76b756368307dbe8c6c4ba 142 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 105 141 8.9E-5 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain DC74_RS25410 dddbf5843331cacb7e1e560bfeb0063d 136 Pfam PF07811 TadE-like protein 19 61 4.2E-9 T 23-04-2016 IPR012495 TadE-like DC74_RS39840 4f0b745410a2289a7124aa762b70ec4a 139 Gene3D G3DSA:3.30.460.10 8 136 8.4E-10 T 23-04-2016 DC74_RS39840 4f0b745410a2289a7124aa762b70ec4a 139 Pfam PF01909 Nucleotidyltransferase domain 26 56 1.6E-5 T 23-04-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DC74_RS39840 4f0b745410a2289a7124aa762b70ec4a 139 SUPERFAMILY SSF81301 9 70 2.45E-10 T 23-04-2016 DC74_RS27525 6443b3c8f2fa31a13a843ba30aa7ef25 282 SUPERFAMILY SSF54637 133 276 1.84E-8 T 23-04-2016 IPR029069 HotDog domain DC74_RS27525 6443b3c8f2fa31a13a843ba30aa7ef25 282 SUPERFAMILY SSF54637 11 103 7.78E-10 T 23-04-2016 IPR029069 HotDog domain DC74_RS27525 6443b3c8f2fa31a13a843ba30aa7ef25 282 Pfam PF13622 Thioesterase-like superfamily 31 276 6.6E-42 T 23-04-2016 DC74_RS27590 57223fe412fc44b5107cdebe5147194f 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 6.7E-25 T 23-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 DC74_RS27590 57223fe412fc44b5107cdebe5147194f 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 7.6E-17 T 23-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 DC74_RS27590 57223fe412fc44b5107cdebe5147194f 98 PANTHER PTHR15004 1 98 1.9E-30 T 23-04-2016 DC74_RS27590 57223fe412fc44b5107cdebe5147194f 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 24.332 T 23-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 DC74_RS27590 57223fe412fc44b5107cdebe5147194f 98 SUPERFAMILY SSF141000 4 94 2.48E-28 T 23-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 DC74_RS30660 1c13bc2356b33f8a1db62f5467d67dfa 264 Pfam PF03771 Domain of unknown function (DUF317) 193 245 1.2E-9 T 23-04-2016 IPR005523 Domain of unknown function DUF317 DC74_RS30660 1c13bc2356b33f8a1db62f5467d67dfa 264 Pfam PF03771 Domain of unknown function (DUF317) 70 137 4.7E-16 T 23-04-2016 IPR005523 Domain of unknown function DUF317 DC74_RS38935 5e6408f30e8a39afb261a02378733fc8 78 Pfam PF09947 Uncharacterized protein conserved in archaea (DUF2180) 1 64 5.6E-7 T 23-04-2016 IPR017211 Uncharacterised conserved protein UCP037465, zinc finger protein, AF1427 DC74_RS33740 eeb6f856458bbd11d978e83ff1bbb15b 367 Pfam PF00704 Glycosyl hydrolases family 18 120 346 5.3E-16 T 23-04-2016 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 DC74_RS33740 eeb6f856458bbd11d978e83ff1bbb15b 367 SUPERFAMILY SSF51445 320 355 1.07E-26 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS33740 eeb6f856458bbd11d978e83ff1bbb15b 367 SUPERFAMILY SSF51445 75 264 1.07E-26 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS33740 eeb6f856458bbd11d978e83ff1bbb15b 367 SMART SM00636 44 348 0.0019 T 23-04-2016 IPR011583 Chitinase II GO:0004568|GO:0006032 DC74_RS33740 eeb6f856458bbd11d978e83ff1bbb15b 367 PANTHER PTHR11177:SF6 19 350 9.3E-24 T 23-04-2016 DC74_RS33740 eeb6f856458bbd11d978e83ff1bbb15b 367 PANTHER PTHR11177 19 350 9.3E-24 T 23-04-2016 DC74_RS33740 eeb6f856458bbd11d978e83ff1bbb15b 367 Gene3D G3DSA:3.20.20.80 102 350 5.6E-18 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS28025 fbb2fa3fe8e1cad5c40f4672f6d011f6 93 Gene3D G3DSA:3.30.70.100 5 93 2.0E-25 T 23-04-2016 DC74_RS28025 fbb2fa3fe8e1cad5c40f4672f6d011f6 93 PANTHER PTHR10029 5 93 2.3E-21 T 23-04-2016 DC74_RS28025 fbb2fa3fe8e1cad5c40f4672f6d011f6 93 SUPERFAMILY SSF54975 3 93 8.07E-23 T 23-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DC74_RS28025 fbb2fa3fe8e1cad5c40f4672f6d011f6 93 Pfam PF00708 Acylphosphatase 5 93 2.0E-20 T 23-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DC74_RS37645 e940b3b0973ae064b94a6662c73f5941 318 Pfam PF04892 VanZ like family 47 111 2.4E-9 T 23-04-2016 IPR006976 VanZ-like DC74_RS13420 8f01855c3c55b7d6d9e3ad3cae71ea6e 246 SMART SM00943 36 219 1.3E-31 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal DC74_RS13420 8f01855c3c55b7d6d9e3ad3cae71ea6e 246 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 39 212 3.5E-24 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal DC74_RS12915 c9d97ddb9ac7fafcc4da5c292f7f2331 132 Pfam PF12270 Cytochrome c oxidase subunit IV 2 129 9.0E-54 T 23-04-2016 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 DC74_RS12915 c9d97ddb9ac7fafcc4da5c292f7f2331 132 PIRSF PIRSF017385 1 131 6.4E-51 T 23-04-2016 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 DC74_RS30185 96c4eb3d1c9f742111e93aa138e53eb5 225 Gene3D G3DSA:1.10.601.10 103 177 9.4E-4 T 23-04-2016 DC74_RS36760 c7cb41266d37d7c91b73b07b2009cba4 258 Pfam PF12483 E3 Ubiquitin ligase 98 248 7.2E-26 T 23-04-2016 IPR022170 Mitochondrial ubiquitin ligase activator of NFKB 1 GO:0004842|GO:0007005 KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.-|UniPathway: UPA00143 DC74_RS06580 072d129e1dba051aace4567ed5ece35e 567 PANTHER PTHR31901:SF5 24 551 9.0E-54 T 23-04-2016 DC74_RS06580 072d129e1dba051aace4567ed5ece35e 567 Pfam PF03321 GH3 auxin-responsive promoter 31 544 1.0E-83 T 23-04-2016 IPR004993 GH3 family KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.- DC74_RS06580 072d129e1dba051aace4567ed5ece35e 567 PANTHER PTHR31901 24 551 9.0E-54 T 23-04-2016 IPR004993 GH3 family KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.- DC74_RS11185 afbc69174be7368757b39c13061bffe7 252 SUPERFAMILY SSF48452 42 128 6.21E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS11185 afbc69174be7368757b39c13061bffe7 252 SUPERFAMILY SSF48452 164 202 6.21E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS11185 afbc69174be7368757b39c13061bffe7 252 Gene3D G3DSA:1.25.40.10 162 208 7.4E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS11185 afbc69174be7368757b39c13061bffe7 252 Gene3D G3DSA:1.25.40.10 30 93 7.4E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS11185 afbc69174be7368757b39c13061bffe7 252 Pfam PF14559 Tetratricopeptide repeat 146 204 1.1E-5 T 23-04-2016 DC74_RS39505 872791701c093c19fedf4db1eb706186 196 PANTHER PTHR30055 2 194 4.2E-33 T 23-04-2016 DC74_RS39505 872791701c093c19fedf4db1eb706186 196 PANTHER PTHR30055:SF66 2 194 4.2E-33 T 23-04-2016 DC74_RS39505 872791701c093c19fedf4db1eb706186 196 Pfam PF16859 Bacterial transcriptional repressor C-terminal 81 187 2.0E-14 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS39505 872791701c093c19fedf4db1eb706186 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 1.6E-11 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39505 872791701c093c19fedf4db1eb706186 196 Gene3D G3DSA:1.10.10.60 9 56 3.5E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39505 872791701c093c19fedf4db1eb706186 196 SUPERFAMILY SSF46689 8 71 1.33E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39505 872791701c093c19fedf4db1eb706186 196 Gene3D G3DSA:1.10.357.10 58 189 4.2E-21 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS39505 872791701c093c19fedf4db1eb706186 196 SUPERFAMILY SSF48498 81 189 4.18E-13 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS18420 0425bef969ecb00e5003e9ebb691c2c6 405 Gene3D G3DSA:3.40.710.10 64 380 7.3E-73 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS18420 0425bef969ecb00e5003e9ebb691c2c6 405 SUPERFAMILY SSF56601 64 380 1.88E-68 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS18420 0425bef969ecb00e5003e9ebb691c2c6 405 PANTHER PTHR22935:SF69 192 376 1.4E-57 T 23-04-2016 DC74_RS18420 0425bef969ecb00e5003e9ebb691c2c6 405 PANTHER PTHR22935:SF69 85 172 1.4E-57 T 23-04-2016 DC74_RS18420 0425bef969ecb00e5003e9ebb691c2c6 405 PANTHER PTHR22935 192 376 1.4E-57 T 23-04-2016 DC74_RS18420 0425bef969ecb00e5003e9ebb691c2c6 405 PANTHER PTHR22935 85 172 1.4E-57 T 23-04-2016 DC74_RS18420 0425bef969ecb00e5003e9ebb691c2c6 405 Pfam PF00144 Beta-lactamase 62 380 2.8E-55 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS18970 596a8162e2384fd16e99796150cc0db7 364 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 71 218 6.8E-29 T 23-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DC74_RS18970 596a8162e2384fd16e99796150cc0db7 364 PANTHER PTHR18968:SF89 25 254 3.4E-122 T 23-04-2016 DC74_RS18970 596a8162e2384fd16e99796150cc0db7 364 SUPERFAMILY SSF52518 35 363 7.68E-85 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS18970 596a8162e2384fd16e99796150cc0db7 364 PANTHER PTHR18968 25 254 3.4E-122 T 23-04-2016 DC74_RS18970 596a8162e2384fd16e99796150cc0db7 364 Gene3D G3DSA:3.40.50.970 21 253 6.8E-84 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold DC74_RS37170 dbcfec4d0403ed772ce2f9fcaa729f39 116 Gene3D G3DSA:1.10.10.10 5 109 6.0E-36 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37170 dbcfec4d0403ed772ce2f9fcaa729f39 116 SUPERFAMILY SSF46785 10 110 4.71E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS37170 dbcfec4d0403ed772ce2f9fcaa729f39 116 PANTHER PTHR33204 1 106 3.4E-33 T 23-04-2016 DC74_RS37170 dbcfec4d0403ed772ce2f9fcaa729f39 116 Pfam PF01638 HxlR-like helix-turn-helix 20 105 1.6E-26 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type DC74_RS34015 96d54f9c74fd7d7a87aebfd822aff234 255 PANTHER PTHR38589:SF1 6 254 5.8E-45 T 23-04-2016 DC74_RS34015 96d54f9c74fd7d7a87aebfd822aff234 255 PANTHER PTHR38589 6 254 5.8E-45 T 23-04-2016 DC74_RS37695 ac75cb50187dbae3ef510343555dc328 378 Pfam PF13810 Domain of unknown function (DUF4185) 75 373 3.9E-51 T 23-04-2016 IPR025442 Domain of unknown function DUF4185 DC74_RS37695 ac75cb50187dbae3ef510343555dc328 378 Gene3D G3DSA:2.120.10.10 167 217 6.4E-4 T 23-04-2016 IPR011040 Sialidases DC74_RS37695 ac75cb50187dbae3ef510343555dc328 378 SUPERFAMILY SSF50939 179 235 7.85E-5 T 23-04-2016 IPR011040 Sialidases DC74_RS37695 ac75cb50187dbae3ef510343555dc328 378 SUPERFAMILY SSF50939 85 111 7.85E-5 T 23-04-2016 IPR011040 Sialidases DC74_RS36260 204ae6fa10092e8f97edbdcd95018278 451 PANTHER PTHR11119 27 433 1.4E-76 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS36260 204ae6fa10092e8f97edbdcd95018278 451 TIGRFAM TIGR03173 pbuX: xanthine permease 32 439 4.1E-126 T 23-04-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 DC74_RS36260 204ae6fa10092e8f97edbdcd95018278 451 Pfam PF00860 Permease family 29 407 3.8E-83 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS36260 204ae6fa10092e8f97edbdcd95018278 451 PANTHER PTHR11119:SF3 27 433 1.4E-76 T 23-04-2016 DC74_RS36260 204ae6fa10092e8f97edbdcd95018278 451 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 28 420 3.0E-92 T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 DC74_RS29330 587c068960f51bed7925b74e9420e356 526 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 3 476 1.7E-204 T 23-04-2016 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial DC74_RS29330 587c068960f51bed7925b74e9420e356 526 Gene3D G3DSA:3.40.50.150 285 448 2.0E-23 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS29330 587c068960f51bed7925b74e9420e356 526 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 2 248 1.3E-111 T 23-04-2016 IPR024740 Hen1, N-terminal DC74_RS29330 587c068960f51bed7925b74e9420e356 526 Pfam PF08242 Methyltransferase domain 302 392 1.3E-11 T 23-04-2016 IPR013217 Methyltransferase type 12 DC74_RS29330 587c068960f51bed7925b74e9420e356 526 PANTHER PTHR21404 1 479 5.4E-93 T 23-04-2016 IPR026610 3'-RNA ribose 2'-O-methyltransferase, Hen1 GO:0001510|GO:0008171|GO:0008173 DC74_RS29330 587c068960f51bed7925b74e9420e356 526 SUPERFAMILY SSF53335 280 450 1.4E-21 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS03290 1b674d6d429327f96c1754d6e177d976 280 SUPERFAMILY SSF53474 40 272 8.65E-30 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS03290 1b674d6d429327f96c1754d6e177d976 280 Gene3D G3DSA:3.40.50.1820 42 275 6.5E-38 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS03290 1b674d6d429327f96c1754d6e177d976 280 Pfam PF12697 Alpha/beta hydrolase family 46 268 1.8E-16 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS03290 1b674d6d429327f96c1754d6e177d976 280 PANTHER PTHR10992:SF832 218 276 2.1E-23 T 23-04-2016 DC74_RS03290 1b674d6d429327f96c1754d6e177d976 280 PANTHER PTHR10992:SF832 41 193 2.1E-23 T 23-04-2016 DC74_RS03290 1b674d6d429327f96c1754d6e177d976 280 PANTHER PTHR10992 218 276 2.1E-23 T 23-04-2016 DC74_RS03290 1b674d6d429327f96c1754d6e177d976 280 PANTHER PTHR10992 41 193 2.1E-23 T 23-04-2016 DC74_RS32850 eb658195599bc5616552578e29cf809b 178 Pfam PF13581 Histidine kinase-like ATPase domain 48 170 4.4E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32850 eb658195599bc5616552578e29cf809b 178 SUPERFAMILY SSF55874 59 170 8.9E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33270 8615cdeeaca3479aa73daef91576e507 87 Pfam PF04149 Domain of unknown function (DUF397) 19 71 4.4E-13 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS11500 2d1094bd9e295098b5fff78112ac041e 429 Pfam PF01384 Phosphate transporter family 22 322 1.4E-73 T 23-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 DC74_RS11500 2d1094bd9e295098b5fff78112ac041e 429 PANTHER PTHR11101:SF54 1 358 7.2E-179 T 23-04-2016 DC74_RS11500 2d1094bd9e295098b5fff78112ac041e 429 PANTHER PTHR11101 1 358 7.2E-179 T 23-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 DC74_RS07400 ac721bc4b89968dad5291c6d66ada8ca 345 SUPERFAMILY SSF56601 9 340 4.93E-56 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS07400 ac721bc4b89968dad5291c6d66ada8ca 345 PANTHER PTHR22935 22 341 6.9E-44 T 23-04-2016 DC74_RS07400 ac721bc4b89968dad5291c6d66ada8ca 345 Gene3D G3DSA:3.40.710.10 23 325 2.3E-55 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS07400 ac721bc4b89968dad5291c6d66ada8ca 345 Pfam PF00144 Beta-lactamase 22 327 4.9E-49 T 23-04-2016 IPR001466 Beta-lactamase-related DC74_RS24575 6263397c51c0313b46ba92b97f5ce92e 142 Pfam PF11222 Protein of unknown function (DUF3017) 50 120 7.1E-22 T 23-04-2016 IPR021385 Protein of unknown function DUF3017 DC74_RS37345 1e0f339cf0cd9f39559e9596c41823c7 295 Gene3D G3DSA:3.50.30.50 20 283 1.6E-51 T 23-04-2016 DC74_RS37345 1e0f339cf0cd9f39559e9596c41823c7 295 PANTHER PTHR31118 21 289 5.6E-32 T 23-04-2016 DC74_RS37345 1e0f339cf0cd9f39559e9596c41823c7 295 Pfam PF04199 Putative cyclase 23 224 7.5E-32 T 23-04-2016 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|UniPathway: UPA00333 DC74_RS37345 1e0f339cf0cd9f39559e9596c41823c7 295 SUPERFAMILY SSF102198 20 282 2.22E-47 T 23-04-2016 DC74_RS10385 19bc9f65e27d82be5a7f7bee5f6cac38 254 Gene3D G3DSA:3.30.450.40 75 250 6.0E-44 T 23-04-2016 IPR029016 GAF domain-like DC74_RS10385 19bc9f65e27d82be5a7f7bee5f6cac38 254 SUPERFAMILY SSF55781 71 250 1.05E-36 T 23-04-2016 IPR029016 GAF domain-like DC74_RS10385 19bc9f65e27d82be5a7f7bee5f6cac38 254 SUPERFAMILY SSF46785 5 77 2.26E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10385 19bc9f65e27d82be5a7f7bee5f6cac38 254 Pfam PF01614 Bacterial transcriptional regulator 123 247 3.8E-32 T 23-04-2016 IPR014757 Transcription regulator IclR, C-terminal DC74_RS10385 19bc9f65e27d82be5a7f7bee5f6cac38 254 Gene3D G3DSA:1.10.10.10 3 74 1.6E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS10385 19bc9f65e27d82be5a7f7bee5f6cac38 254 PANTHER PTHR30136 3 250 4.9E-97 T 23-04-2016 DC74_RS10385 19bc9f65e27d82be5a7f7bee5f6cac38 254 PANTHER PTHR30136:SF13 3 250 4.9E-97 T 23-04-2016 DC74_RS10385 19bc9f65e27d82be5a7f7bee5f6cac38 254 Pfam PF09339 IclR helix-turn-helix domain 7 57 1.7E-16 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS10385 19bc9f65e27d82be5a7f7bee5f6cac38 254 SMART SM00346 5 95 2.4E-35 T 23-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DC74_RS27950 811ea98d0b7409bfc5ac9b84da38f1da 164 Pfam PF12028 Protein of unknown function (DUF3515) 17 162 2.1E-23 T 23-04-2016 IPR021903 Protein of unknown function DUF3515 DC74_RS21660 6394ecdff27882eac037db958adbd0a2 205 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 88 177 3.9E-17 T 23-04-2016 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain DC74_RS36090 9ee9e3a6b9d774b17276ab7294280216 124 PANTHER PTHR30007:SF0 1 118 2.7E-23 T 23-04-2016 DC74_RS36090 9ee9e3a6b9d774b17276ab7294280216 124 PANTHER PTHR30007 1 118 2.7E-23 T 23-04-2016 DC74_RS36090 9ee9e3a6b9d774b17276ab7294280216 124 Pfam PF01609 Transposase DDE domain 2 64 2.3E-9 T 23-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 DC74_RS32780 cdccbd079e559da04f683653765ebb84 236 PANTHER PTHR36933 64 236 3.8E-34 T 23-04-2016 DC74_RS32780 cdccbd079e559da04f683653765ebb84 236 Pfam PF03713 Domain of unknown function (DUF305) 73 233 1.6E-51 T 23-04-2016 IPR005183 Domain of unknown function DUF305 DC74_RS32780 cdccbd079e559da04f683653765ebb84 236 PANTHER PTHR36933:SF1 64 236 3.8E-34 T 23-04-2016 DC74_RS32780 cdccbd079e559da04f683653765ebb84 236 Gene3D G3DSA:1.20.1260.10 71 235 3.6E-59 T 23-04-2016 IPR012347 Ferritin-related DC74_RS08715 6870cc0bd268d267043ac5e47cd51ad0 265 SUPERFAMILY SSF53681 2 102 7.85E-21 T 23-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS08715 6870cc0bd268d267043ac5e47cd51ad0 265 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 67 75 - T 23-04-2016 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS08715 6870cc0bd268d267043ac5e47cd51ad0 265 Gene3D G3DSA:3.40.50.1860 2 160 2.4E-33 T 23-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS08715 6870cc0bd268d267043ac5e47cd51ad0 265 PANTHER PTHR21198:SF2 2 260 1.3E-67 T 23-04-2016 DC74_RS08715 6870cc0bd268d267043ac5e47cd51ad0 265 SUPERFAMILY SSF53681 106 244 1.66E-19 T 23-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS08715 6870cc0bd268d267043ac5e47cd51ad0 265 Pfam PF01177 Asp/Glu/Hydantoin racemase 44 200 2.4E-14 T 23-04-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 DC74_RS08715 6870cc0bd268d267043ac5e47cd51ad0 265 PANTHER PTHR21198 2 260 1.3E-67 T 23-04-2016 DC74_RS35340 8babe690403322c1b57952c2d1271484 139 Pfam PF06841 T4-like virus tail tube protein gp19 52 134 3.7E-8 T 23-04-2016 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PANTHER PTHR24322:SF413 155 185 8.5E-93 T 23-04-2016 DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PANTHER PTHR24322:SF413 11 139 8.5E-93 T 23-04-2016 DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.6E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.6E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.6E-6 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PANTHER PTHR24322 155 185 8.5E-93 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PANTHER PTHR24322 11 139 8.5E-93 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 SUPERFAMILY SSF51735 4 237 3.68E-67 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 Pfam PF00106 short chain dehydrogenase 7 195 4.2E-49 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 Gene3D G3DSA:3.40.50.720 4 235 1.2E-66 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.5E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 2.5E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.5E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.5E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.5E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS00800 33fed66860a180b639e5c5cfb09041fa 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.5E-25 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS34220 dac44702645efb2ff760e96bec24d88f 146 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 136 5.6E-12 T 23-04-2016 IPR019587 Polyketide cyclase/dehydrase DC74_RS34220 dac44702645efb2ff760e96bec24d88f 146 Gene3D G3DSA:3.30.530.20 3 141 1.8E-11 T 23-04-2016 IPR023393 START-like domain DC74_RS34220 dac44702645efb2ff760e96bec24d88f 146 SUPERFAMILY SSF55961 1 141 3.46E-20 T 23-04-2016 DC74_RS13370 f831c52f5dfaa8c333857ad3727dfa96 283 PANTHER PTHR32243 2 283 4.2E-109 T 23-04-2016 DC74_RS13370 f831c52f5dfaa8c333857ad3727dfa96 283 Gene3D G3DSA:1.10.3720.10 9 270 2.5E-45 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS13370 f831c52f5dfaa8c333857ad3727dfa96 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 271 3.6E-16 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS13370 f831c52f5dfaa8c333857ad3727dfa96 283 SUPERFAMILY SSF161098 9 282 1.1E-48 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS13370 f831c52f5dfaa8c333857ad3727dfa96 283 PANTHER PTHR32243:SF28 2 283 4.2E-109 T 23-04-2016 DC74_RS24300 bf1087dab008dbbc6afd405c3d8ab896 252 Pfam PF14023 Protein of unknown function (DUF4239) 48 235 5.2E-21 T 23-04-2016 IPR025333 Protein of unknown function DUF4239 DC74_RS20700 1f9e0f3883a9657f088623aef6ac2d05 151 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 4 116 1.5E-15 T 23-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 DC74_RS20700 1f9e0f3883a9657f088623aef6ac2d05 151 SUPERFAMILY SSF54211 2 118 5.31E-23 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold DC74_RS20700 1f9e0f3883a9657f088623aef6ac2d05 151 Pfam PF00825 Ribonuclease P 2 117 8.7E-27 T 23-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 DC74_RS20700 1f9e0f3883a9657f088623aef6ac2d05 151 PANTHER PTHR33992 1 138 3.1E-32 T 23-04-2016 DC74_RS20700 1f9e0f3883a9657f088623aef6ac2d05 151 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 120 16.401 T 23-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 DC74_RS20700 1f9e0f3883a9657f088623aef6ac2d05 151 Gene3D G3DSA:3.30.230.10 2 117 7.2E-32 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DC74_RS31015 e944c112e3b62b1b5cd9b82ad7649a18 486 TIGRFAM TIGR03173 pbuX: xanthine permease 32 446 3.4E-152 T 23-04-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 DC74_RS31015 e944c112e3b62b1b5cd9b82ad7649a18 486 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 25 444 2.3E-109 T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 DC74_RS31015 e944c112e3b62b1b5cd9b82ad7649a18 486 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 361 381 - T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 DC74_RS31015 e944c112e3b62b1b5cd9b82ad7649a18 486 PANTHER PTHR11119 16 471 2.1E-120 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS31015 e944c112e3b62b1b5cd9b82ad7649a18 486 SUPERFAMILY SSF103473 26 162 6.41E-6 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS31015 e944c112e3b62b1b5cd9b82ad7649a18 486 Pfam PF00860 Permease family 28 409 2.7E-100 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS03685 2fe5d593e813a4068ee9ee848d665c32 200 SUPERFAMILY SSF46689 1 68 2.77E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS03685 2fe5d593e813a4068ee9ee848d665c32 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 57 1.5E-8 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS03685 2fe5d593e813a4068ee9ee848d665c32 200 Gene3D G3DSA:1.10.357.10 1 197 3.7E-36 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS03685 2fe5d593e813a4068ee9ee848d665c32 200 Pfam PF13977 Bacterial transcriptional repressor 85 196 1.3E-11 T 23-04-2016 DC74_RS03685 2fe5d593e813a4068ee9ee848d665c32 200 SUPERFAMILY SSF48498 83 195 1.65E-12 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS03685 2fe5d593e813a4068ee9ee848d665c32 200 PANTHER PTHR30055 2 167 6.8E-18 T 23-04-2016 DC74_RS03610 0b1a56cd9e797492c33655f5227c1d4b 405 PANTHER PTHR24421:SF26 79 405 3.7E-44 T 23-04-2016 DC74_RS03610 0b1a56cd9e797492c33655f5227c1d4b 405 Pfam PF07730 Histidine kinase 209 274 1.7E-11 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS03610 0b1a56cd9e797492c33655f5227c1d4b 405 SUPERFAMILY SSF55874 277 396 8.43E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS03610 0b1a56cd9e797492c33655f5227c1d4b 405 PANTHER PTHR24421 79 405 3.7E-44 T 23-04-2016 DC74_RS31145 7ac52c63e300bef0488767b7976d2619 281 Gene3D G3DSA:1.25.40.10 79 233 2.1E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 73 6.0E-24 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 76 20.759 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 SUPERFAMILY SSF46911 5 75 1.44E-28 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 3.5E-30 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 Pfam PF01084 Ribosomal protein S18 21 71 4.5E-24 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 PANTHER PTHR13479 2 78 7.2E-50 T 23-04-2016 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 4.8E-16 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 4.8E-16 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 4.8E-16 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 4.8E-16 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 23-04-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 Gene3D G3DSA:4.10.640.10 11 75 1.4E-32 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DC74_RS20830 4ffc663cab710c493b36e79c3661076a 78 PANTHER PTHR13479:SF42 2 78 7.2E-50 T 23-04-2016 DC74_RS11325 9f0a272811f85d66c9bc4bdccb0d1517 522 PANTHER PTHR30624 9 518 2.8E-201 T 23-04-2016 DC74_RS11325 9f0a272811f85d66c9bc4bdccb0d1517 522 PANTHER PTHR30624:SF10 9 518 2.8E-201 T 23-04-2016 DC74_RS11325 9f0a272811f85d66c9bc4bdccb0d1517 522 Pfam PF01523 Putative modulator of DNA gyrase 35 362 7.5E-46 T 23-04-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS11325 9f0a272811f85d66c9bc4bdccb0d1517 522 SUPERFAMILY SSF111283 16 513 4.05E-87 T 23-04-2016 DC74_RS33440 9ee7f7eede3c9f37a06e67ce0c43a3d3 254 SUPERFAMILY SSF55729 53 249 1.06E-23 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS33440 9ee7f7eede3c9f37a06e67ce0c43a3d3 254 Pfam PF13673 Acetyltransferase (GNAT) domain 145 248 1.9E-8 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS33440 9ee7f7eede3c9f37a06e67ce0c43a3d3 254 Gene3D G3DSA:3.40.630.30 124 248 2.5E-19 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS30100 863094590026a31302d01d68e0105cd3 731 Gene3D G3DSA:3.40.50.300 186 406 3.3E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30100 863094590026a31302d01d68e0105cd3 731 SUPERFAMILY SSF52540 306 560 5.05E-29 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30100 863094590026a31302d01d68e0105cd3 731 SUPERFAMILY SSF52540 216 266 5.05E-29 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30100 863094590026a31302d01d68e0105cd3 731 Gene3D G3DSA:3.40.50.300 434 575 7.1E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30100 863094590026a31302d01d68e0105cd3 731 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 3 157 5.1E-18 T 23-04-2016 IPR006483 CRISPR-associated Cas3-HD domain DC74_RS25755 129c7d86d6c4339ab2b7706c9b4edfb8 59 Pfam PF05036 Sporulation related domain 11 45 8.8E-5 T 23-04-2016 IPR007730 Sporulation-related domain GO:0042834 DC74_RS25755 129c7d86d6c4339ab2b7706c9b4edfb8 59 Gene3D G3DSA:3.30.70.1070 13 44 8.1E-4 T 23-04-2016 IPR007730 Sporulation-related domain GO:0042834 DC74_RS19080 503de347805d7db07c75275bd6700f4c 268 Gene3D G3DSA:3.90.1720.10 149 268 4.8E-35 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS19080 503de347805d7db07c75275bd6700f4c 268 SUPERFAMILY SSF54001 149 267 2.99E-34 T 23-04-2016 DC74_RS19080 503de347805d7db07c75275bd6700f4c 268 PANTHER PTHR21666 142 252 1.1E-22 T 23-04-2016 DC74_RS19080 503de347805d7db07c75275bd6700f4c 268 Pfam PF00877 NlpC/P60 family 166 257 1.3E-19 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS24440 d91cb0f1e028a74ce65ae97f5b679a2a 1297 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 608 1186 2.2E-53 T 23-04-2016 IPR011749 Conserved hypothetical protein CHP02243 DC74_RS24440 d91cb0f1e028a74ce65ae97f5b679a2a 1297 Pfam PF01476 LysM domain 1232 1270 2.8E-4 T 23-04-2016 IPR018392 LysM domain DC74_RS23550 6caac87ec09e4b2cab766a72feb02a31 409 Gene3D G3DSA:3.40.50.1820 60 200 6.8E-10 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS23550 6caac87ec09e4b2cab766a72feb02a31 409 SUPERFAMILY SSF53474 59 231 4.16E-13 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS34460 2d3d5944617468d712af04556a7bca4c 551 Pfam PF01566 Natural resistance-associated macrophage protein 72 428 5.1E-79 T 23-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 DC74_RS04180 436cdffe45a3ecba66527ade0f1c5747 555 PANTHER PTHR11785 449 512 4.3E-98 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS04180 436cdffe45a3ecba66527ade0f1c5747 555 PANTHER PTHR11785 9 404 4.3E-98 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS04180 436cdffe45a3ecba66527ade0f1c5747 555 PIRSF PIRSF006060 1 530 5.2E-65 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS04180 436cdffe45a3ecba66527ade0f1c5747 555 Pfam PF13520 Amino acid permease 11 421 4.7E-46 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS04180 436cdffe45a3ecba66527ade0f1c5747 555 PANTHER PTHR11785:SF322 449 512 4.3E-98 T 23-04-2016 DC74_RS04180 436cdffe45a3ecba66527ade0f1c5747 555 PANTHER PTHR11785:SF322 9 404 4.3E-98 T 23-04-2016 DC74_RS35090 04b482d33028cbbe3535a4c887f910ea 645 Pfam PF13401 AAA domain 30 126 4.7E-7 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS35090 04b482d33028cbbe3535a4c887f910ea 645 Gene3D G3DSA:1.25.40.10 402 528 9.6E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS35090 04b482d33028cbbe3535a4c887f910ea 645 SUPERFAMILY SSF52540 10 206 3.29E-16 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35090 04b482d33028cbbe3535a4c887f910ea 645 Gene3D G3DSA:3.40.50.300 31 146 5.3E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS35090 04b482d33028cbbe3535a4c887f910ea 645 PRINTS PR00364 Disease resistance protein signature 32 47 3.5E-5 T 23-04-2016 DC74_RS35090 04b482d33028cbbe3535a4c887f910ea 645 PRINTS PR00364 Disease resistance protein signature 191 205 3.5E-5 T 23-04-2016 DC74_RS35090 04b482d33028cbbe3535a4c887f910ea 645 PRINTS PR00364 Disease resistance protein signature 99 113 3.5E-5 T 23-04-2016 DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 SUPERFAMILY SSF54909 75 155 1.02E-13 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 Gene3D G3DSA:3.30.70.920 77 147 7.4E-15 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 Gene3D G3DSA:1.10.10.10 11 56 4.7E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 Gene3D G3DSA:1.10.10.10 185 229 5.5E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 SUPERFAMILY SSF46785 185 233 1.7E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 Pfam PF01037 Lrp/AsnC ligand binding domain 79 146 1.1E-12 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 202 213 2.1E-6 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 213 232 2.1E-6 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 186 202 2.1E-6 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 SMART SM00344 186 291 5.5E-5 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 SMART SM00344 12 119 1.7E-6 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 PANTHER PTHR30154 4 174 5.9E-24 T 23-04-2016 DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 Pfam PF13404 AsnC-type helix-turn-helix domain 12 52 1.3E-12 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS38790 a982b518d96e51b2c8f05bab1c91031f 354 Pfam PF13404 AsnC-type helix-turn-helix domain 186 226 1.8E-12 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS32950 9ac5c863694848a3c07d4b802567a46d 197 PANTHER PTHR30055:SF80 1 186 8.2E-31 T 23-04-2016 DC74_RS32950 9ac5c863694848a3c07d4b802567a46d 197 PANTHER PTHR30055 1 186 8.2E-31 T 23-04-2016 DC74_RS32950 9ac5c863694848a3c07d4b802567a46d 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 9.5E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS32950 9ac5c863694848a3c07d4b802567a46d 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 9.5E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS32950 9ac5c863694848a3c07d4b802567a46d 197 Gene3D G3DSA:1.10.357.10 57 187 3.1E-26 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS32950 9ac5c863694848a3c07d4b802567a46d 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 54 5.8E-12 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS32950 9ac5c863694848a3c07d4b802567a46d 197 SUPERFAMILY SSF46689 2 71 3.36E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS32950 9ac5c863694848a3c07d4b802567a46d 197 Gene3D G3DSA:1.10.10.60 2 56 9.3E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS06530 8d5264918bc2bd971db415a2e2d05dbb 274 SUPERFAMILY SSF54593 20 234 2.07E-18 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS06530 8d5264918bc2bd971db415a2e2d05dbb 274 Gene3D G3DSA:3.10.180.10 145 265 1.7E-17 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS06530 8d5264918bc2bd971db415a2e2d05dbb 274 Gene3D G3DSA:3.10.180.10 20 131 4.3E-26 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS06530 8d5264918bc2bd971db415a2e2d05dbb 274 PANTHER PTHR33993:SF3 1 271 2.3E-69 T 23-04-2016 DC74_RS06530 8d5264918bc2bd971db415a2e2d05dbb 274 PANTHER PTHR33993 1 271 2.3E-69 T 23-04-2016 DC74_RS06985 e7c7048e5bc92b0bd91e93eeacad142d 104 Gene3D G3DSA:2.60.120.10 17 100 8.6E-17 T 23-04-2016 IPR014710 RmlC-like jelly roll fold DC74_RS06985 e7c7048e5bc92b0bd91e93eeacad142d 104 SUPERFAMILY SSF51182 12 100 5.35E-16 T 23-04-2016 IPR011051 RmlC-like cupin domain DC74_RS06985 e7c7048e5bc92b0bd91e93eeacad142d 104 Pfam PF12973 ChrR Cupin-like domain 19 99 1.7E-15 T 23-04-2016 IPR025979 ChrR-like cupin domain DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 Pfam PF02887 Pyruvate kinase, alpha/beta domain 357 469 1.2E-28 T 23-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 Gene3D G3DSA:2.40.33.10 73 167 7.4E-29 T 23-04-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 Pfam PF00224 Pyruvate kinase, barrel domain 1 337 6.4E-125 T 23-04-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 Gene3D G3DSA:3.20.20.60 168 324 7.9E-102 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 Gene3D G3DSA:3.20.20.60 2 72 7.9E-102 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.3E-65 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 PRINTS PR01050 Pyruvate kinase family signature 215 241 1.3E-65 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 PRINTS PR01050 Pyruvate kinase family signature 242 266 1.3E-65 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 PRINTS PR01050 Pyruvate kinase family signature 185 199 1.3E-65 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 PRINTS PR01050 Pyruvate kinase family signature 311 327 1.3E-65 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 PRINTS PR01050 Pyruvate kinase family signature 292 310 1.3E-65 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 PRINTS PR01050 Pyruvate kinase family signature 267 291 1.3E-65 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 SUPERFAMILY SSF50800 70 165 1.92E-26 T 23-04-2016 IPR011037 Pyruvate kinase-like, insert domain DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 Gene3D G3DSA:3.40.1380.20 325 471 3.3E-44 T 23-04-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 471 4.4E-166 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 SUPERFAMILY SSF52935 321 471 3.01E-39 T 23-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 SUPERFAMILY SSF51621 155 338 2.86E-96 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 SUPERFAMILY SSF51621 1 74 2.86E-96 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 23-04-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS12130 15ac49ea34003fedf31303d75914c2b6 480 PANTHER PTHR11817 1 476 5.7E-220 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 DC74_RS08555 6631b46f06485e638d32da48b5b0aa7c 392 SUPERFAMILY SSF51556 18 365 6.43E-76 T 23-04-2016 IPR032466 Metal-dependent hydrolase DC74_RS08555 6631b46f06485e638d32da48b5b0aa7c 392 Hamap MF_00540 Adenosine deaminase [add]. 21 366 52.018 T 23-04-2016 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 DC74_RS08555 6631b46f06485e638d32da48b5b0aa7c 392 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 27 364 5.1E-76 T 23-04-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 DC74_RS08555 6631b46f06485e638d32da48b5b0aa7c 392 PANTHER PTHR11409 16 366 7.8E-104 T 23-04-2016 DC74_RS08555 6631b46f06485e638d32da48b5b0aa7c 392 Pfam PF00962 Adenosine/AMP deaminase 26 363 3.0E-83 T 23-04-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 DC74_RS08555 6631b46f06485e638d32da48b5b0aa7c 392 Gene3D G3DSA:3.20.20.140 23 365 2.3E-101 T 23-04-2016 DC74_RS08555 6631b46f06485e638d32da48b5b0aa7c 392 PANTHER PTHR11409:SF43 16 366 7.8E-104 T 23-04-2016 DC74_RS23625 25729cadaaf72998b0b04ea29c3e43de 759 Gene3D G3DSA:2.115.10.10 609 753 1.1E-15 T 23-04-2016 IPR023294 Tachylectin 2 DC74_RS23625 25729cadaaf72998b0b04ea29c3e43de 759 SUPERFAMILY SSF69318 469 739 6.8E-25 T 23-04-2016 DC74_RS04280 504843563ea8fe8cafa0dd433c1ecbfc 117 Gene3D G3DSA:3.30.70.900 26 113 1.8E-12 T 23-04-2016 DC74_RS04280 504843563ea8fe8cafa0dd433c1ecbfc 117 PANTHER PTHR37811 7 116 4.5E-27 T 23-04-2016 DC74_RS04280 504843563ea8fe8cafa0dd433c1ecbfc 117 Pfam PF03992 Antibiotic biosynthesis monooxygenase 22 92 1.4E-5 T 23-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain DC74_RS04280 504843563ea8fe8cafa0dd433c1ecbfc 117 SUPERFAMILY SSF54909 13 115 2.02E-28 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS04280 504843563ea8fe8cafa0dd433c1ecbfc 117 PANTHER PTHR37811:SF2 7 116 4.5E-27 T 23-04-2016 DC74_RS03635 5342e6c4e374fbef3c9a3075978341ba 458 SUPERFAMILY SSF103473 13 197 3.79E-36 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS03635 5342e6c4e374fbef3c9a3075978341ba 458 SUPERFAMILY SSF103473 245 456 3.79E-36 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS03635 5342e6c4e374fbef3c9a3075978341ba 458 PANTHER PTHR23501 17 457 5.2E-51 T 23-04-2016 DC74_RS03635 5342e6c4e374fbef3c9a3075978341ba 458 Gene3D G3DSA:1.20.1250.20 12 181 1.4E-18 T 23-04-2016 DC74_RS03635 5342e6c4e374fbef3c9a3075978341ba 458 Gene3D G3DSA:1.20.1250.20 275 457 5.9E-10 T 23-04-2016 DC74_RS03635 5342e6c4e374fbef3c9a3075978341ba 458 Pfam PF07690 Major Facilitator Superfamily 17 410 1.3E-23 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS35080 d4bc19a9678fe21bf13589a8ddbbf803 220 PANTHER PTHR30353 2 213 4.8E-92 T 23-04-2016 IPR032818 DedA family DC74_RS35080 d4bc19a9678fe21bf13589a8ddbbf803 220 Pfam PF09335 SNARE associated Golgi protein 32 160 2.9E-20 T 23-04-2016 IPR032816 SNARE associated Golgi protein DC74_RS35080 d4bc19a9678fe21bf13589a8ddbbf803 220 PANTHER PTHR30353:SF2 2 213 4.8E-92 T 23-04-2016 DC74_RS10050 1dddb6011c1715a1be2e8590ee4ea1de 398 SUPERFAMILY SSF53756 5 332 6.28E-7 T 23-04-2016 DC74_RS32670 2959c351335949754a2317aa342e6693 360 Gene3D G3DSA:3.40.50.300 140 183 9.0E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS32670 2959c351335949754a2317aa342e6693 360 SUPERFAMILY SSF53795 141 213 6.41E-10 T 23-04-2016 DC74_RS16895 2f3a3d9741d1702c0b51477e245d5d59 410 Pfam PF14258 Domain of unknown function (DUF4350) 55 125 1.2E-11 T 23-04-2016 IPR025646 Domain of unknown function DUF4350 DC74_RS28895 bd4da368ed5391303dcf860e346edb64 388 Gene3D G3DSA:2.40.10.10 150 255 2.7E-7 T 23-04-2016 DC74_RS28895 bd4da368ed5391303dcf860e346edb64 388 SUPERFAMILY SSF50494 246 357 1.57E-16 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS28895 bd4da368ed5391303dcf860e346edb64 388 SUPERFAMILY SSF50494 132 219 1.57E-16 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS10510 6504c1e1c3967b2a569307c65fade308 295 Pfam PF03777 Small secreted domain (DUF320) 24 79 2.3E-27 T 23-04-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species DC74_RS10510 6504c1e1c3967b2a569307c65fade308 295 Pfam PF03777 Small secreted domain (DUF320) 102 155 2.1E-25 T 23-04-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species DC74_RS05850 f7a0953ac3ea36c3b27e6b4005602134 176 Pfam PF11706 CGNR zinc finger 129 171 2.5E-11 T 23-04-2016 IPR021005 Zinc finger, CGNR DC74_RS05850 f7a0953ac3ea36c3b27e6b4005602134 176 Gene3D G3DSA:1.10.3300.10 23 172 4.7E-34 T 23-04-2016 IPR023286 ABATE domain DC74_RS05850 f7a0953ac3ea36c3b27e6b4005602134 176 SUPERFAMILY SSF160904 4 170 1.83E-34 T 23-04-2016 DC74_RS14500 feaec75f72575898fc3c07b05510fe1f 497 Pfam PF03237 Terminase-like family 78 473 2.9E-31 T 23-04-2016 IPR004921 Terminase, large subunit DC74_RS02475 6b375c04b0eb823ceae52becec7d3dcc 566 Pfam PF03321 GH3 auxin-responsive promoter 32 550 8.6E-99 T 23-04-2016 IPR004993 GH3 family KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.- DC74_RS02475 6b375c04b0eb823ceae52becec7d3dcc 566 PANTHER PTHR31901:SF5 44 559 1.3E-50 T 23-04-2016 DC74_RS02475 6b375c04b0eb823ceae52becec7d3dcc 566 PANTHER PTHR31901 44 559 1.3E-50 T 23-04-2016 IPR004993 GH3 family KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.- DC74_RS31700 595bea72d2249c474193a919821aa0ce 473 PANTHER PTHR10668:SF74 1 469 2.4E-189 T 23-04-2016 DC74_RS31700 595bea72d2249c474193a919821aa0ce 473 PRINTS PR00419 Adrenodoxin reductase family signature 29 42 4.5E-5 T 23-04-2016 DC74_RS31700 595bea72d2249c474193a919821aa0ce 473 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 4.5E-5 T 23-04-2016 DC74_RS31700 595bea72d2249c474193a919821aa0ce 473 Gene3D G3DSA:3.50.50.60 435 469 2.3E-6 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS31700 595bea72d2249c474193a919821aa0ce 473 Gene3D G3DSA:3.50.50.60 204 288 2.3E-6 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS31700 595bea72d2249c474193a919821aa0ce 473 Gene3D G3DSA:3.50.50.60 6 104 1.8E-17 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS31700 595bea72d2249c474193a919821aa0ce 473 SUPERFAMILY SSF51905 424 468 1.62E-30 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS31700 595bea72d2249c474193a919821aa0ce 473 SUPERFAMILY SSF51905 5 300 1.62E-30 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS31700 595bea72d2249c474193a919821aa0ce 473 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 57 1.1E-11 T 23-04-2016 DC74_RS31700 595bea72d2249c474193a919821aa0ce 473 PANTHER PTHR10668 1 469 2.4E-189 T 23-04-2016 DC74_RS21555 b94e89e6a077ccc7f8152ac8812cebfb 273 SMART SM00530 19 73 0.0061 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS21555 b94e89e6a077ccc7f8152ac8812cebfb 273 SUPERFAMILY SSF47413 13 67 4.69E-8 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS21555 b94e89e6a077ccc7f8152ac8812cebfb 273 Gene3D G3DSA:1.10.260.40 14 64 1.0E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS21555 b94e89e6a077ccc7f8152ac8812cebfb 273 PANTHER PTHR10245:SF7 16 273 4.6E-37 T 23-04-2016 DC74_RS21555 b94e89e6a077ccc7f8152ac8812cebfb 273 PANTHER PTHR10245 16 273 4.6E-37 T 23-04-2016 DC74_RS21555 b94e89e6a077ccc7f8152ac8812cebfb 273 Pfam PF13560 Helix-turn-helix domain 16 73 6.1E-10 T 23-04-2016 DC74_RS34520 fd22a07d6effb40c8108a2aa9d46342e 134 PIRSF PIRSF009151 3 134 1.5E-58 T 23-04-2016 IPR008497 Protein of unknown function DUF779 DC74_RS34520 fd22a07d6effb40c8108a2aa9d46342e 134 Pfam PF05610 Protein of unknown function (DUF779) 24 123 1.6E-46 T 23-04-2016 IPR008497 Protein of unknown function DUF779 DC74_RS30075 37a1ab94102b265a7d13b8d52f898614 77 Pfam PF04149 Domain of unknown function (DUF397) 15 67 2.4E-16 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS30300 d65a214236959f377aa6545e25db2218 487 PANTHER PTHR30108 3 485 3.1E-115 T 23-04-2016 DC74_RS30300 d65a214236959f377aa6545e25db2218 487 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 421 1.5E-109 T 23-04-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 DC74_RS30300 d65a214236959f377aa6545e25db2218 487 Gene3D G3DSA:3.40.1670.10 330 454 3.6E-12 T 23-04-2016 DC74_RS30300 d65a214236959f377aa6545e25db2218 487 SUPERFAMILY SSF143968 315 486 1.96E-27 T 23-04-2016 DC74_RS30300 d65a214236959f377aa6545e25db2218 487 SUPERFAMILY SSF50475 5 313 2.28E-88 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS30300 d65a214236959f377aa6545e25db2218 487 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 7 432 2.3E-93 T 23-04-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 DC74_RS30300 d65a214236959f377aa6545e25db2218 487 Hamap MF_01983 UbiD-like decarboxylase. 3 487 44.614 T 23-04-2016 IPR032903 UbiD-like decarboxylase/ferulic acid decarboxylase 1 DC74_RS30300 d65a214236959f377aa6545e25db2218 487 PANTHER PTHR30108:SF1 3 485 3.1E-115 T 23-04-2016 DC74_RS25885 3735f09774ca61ef692a83a56961d668 300 PANTHER PTHR24220:SF364 3 232 1.5E-111 T 23-04-2016 DC74_RS25885 3735f09774ca61ef692a83a56961d668 300 SUPERFAMILY SSF52540 2 217 1.68E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25885 3735f09774ca61ef692a83a56961d668 300 PANTHER PTHR24220 3 232 1.5E-111 T 23-04-2016 DC74_RS25885 3735f09774ca61ef692a83a56961d668 300 SMART SM00382 26 202 1.4E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS25885 3735f09774ca61ef692a83a56961d668 300 Gene3D G3DSA:3.40.50.300 2 219 5.4E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25885 3735f09774ca61ef692a83a56961d668 300 Pfam PF00005 ABC transporter 19 153 9.8E-25 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS37650 43bd4618f6757fced81ed2b6ace8bd78 541 Gene3D G3DSA:1.10.260.40 30 73 8.4E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS37650 43bd4618f6757fced81ed2b6ace8bd78 541 Pfam PF01381 Helix-turn-helix 30 64 1.0E-8 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS37650 43bd4618f6757fced81ed2b6ace8bd78 541 SMART SM00530 28 81 1.5E-4 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS37650 43bd4618f6757fced81ed2b6ace8bd78 541 SUPERFAMILY SSF47413 30 74 4.44E-8 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS36270 8641a77867903c574000e59e8fab75b3 400 Gene3D G3DSA:1.20.1250.20 18 197 1.9E-25 T 23-04-2016 DC74_RS36270 8641a77867903c574000e59e8fab75b3 400 Gene3D G3DSA:1.20.1250.20 217 385 1.0E-9 T 23-04-2016 DC74_RS36270 8641a77867903c574000e59e8fab75b3 400 SUPERFAMILY SSF103473 15 389 3.53E-42 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS36270 8641a77867903c574000e59e8fab75b3 400 Pfam PF07690 Major Facilitator Superfamily 20 285 1.3E-22 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS25190 81c3ba6b0a9880cf0699772f6d26966d 294 Pfam PF01609 Transposase DDE domain 104 271 7.5E-9 T 23-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 DC74_RS24165 834907170ce326c36cdde87d4636bc1c 173 Gene3D G3DSA:3.40.50.300 60 168 1.7E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS39855 b36d93f7908742ad5e1a99a381964072 422 PANTHER PTHR12714:SF7 192 312 8.8E-12 T 23-04-2016 DC74_RS39855 b36d93f7908742ad5e1a99a381964072 422 Pfam PF04191 Phospholipid methyltransferase 228 293 7.7E-7 T 23-04-2016 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|UniPathway: UPA00753 DC74_RS39855 b36d93f7908742ad5e1a99a381964072 422 PANTHER PTHR12714 192 312 8.8E-12 T 23-04-2016 DC74_RS03335 749e32d0b0758cb0a73ec32683ce4bbf 165 SUPERFAMILY SSF50370 2 93 3.07E-9 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS03335 749e32d0b0758cb0a73ec32683ce4bbf 165 Gene3D G3DSA:2.80.10.50 1 64 1.9E-7 T 23-04-2016 DC74_RS10020 e515f2e3d2a080035ed3d454a9e1abcb 1017 Pfam PF04738 Lantibiotic dehydratase, C terminus 42 672 1.3E-161 T 23-04-2016 IPR006827 Lantibiotic dehydratase, C-terminal DC74_RS10020 e515f2e3d2a080035ed3d454a9e1abcb 1017 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 743 1002 1.9E-32 T 23-04-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain DC74_RS10020 e515f2e3d2a080035ed3d454a9e1abcb 1017 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 743 1001 2.8E-48 T 23-04-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain DC74_RS35635 beaf3c835053e6c5aae3a520ddcf4bbd 124 SUPERFAMILY SSF103196 3 122 6.8E-5 T 23-04-2016 DC74_RS16140 3aa7f5f9280705bdd129fd3ebcbd844b 175 Pfam PF04978 Protein of unknown function (DUF664) 21 171 1.1E-49 T 23-04-2016 IPR007061 Protein of unknown function DUF664 DC74_RS16140 3aa7f5f9280705bdd129fd3ebcbd844b 175 Gene3D G3DSA:1.20.120.450 1 175 5.6E-54 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS16140 3aa7f5f9280705bdd129fd3ebcbd844b 175 SUPERFAMILY SSF109854 4 170 1.83E-45 T 23-04-2016 DC74_RS37600 a54c31be59007bdbf264c747d508c480 485 PANTHER PTHR13806:SF20 1 455 1.3E-114 T 23-04-2016 DC74_RS37600 a54c31be59007bdbf264c747d508c480 485 Pfam PF15975 Flotillin 344 438 1.6E-10 T 23-04-2016 IPR031905 Flotillin, C-terminal domain DC74_RS37600 a54c31be59007bdbf264c747d508c480 485 SUPERFAMILY SSF117892 71 210 3.66E-26 T 23-04-2016 IPR001107 Band 7 domain DC74_RS37600 a54c31be59007bdbf264c747d508c480 485 PANTHER PTHR13806 1 455 1.3E-114 T 23-04-2016 IPR027705 Flotillin family DC74_RS37600 a54c31be59007bdbf264c747d508c480 485 Pfam PF01145 SPFH domain / Band 7 family 29 221 8.1E-27 T 23-04-2016 IPR001107 Band 7 domain DC74_RS37600 a54c31be59007bdbf264c747d508c480 485 SMART SM00244 24 205 8.7E-4 T 23-04-2016 IPR001107 Band 7 domain DC74_RS07425 0acb1841a641ebce6ea39da07f9be22d 318 PANTHER PTHR40277 1 312 6.8E-40 T 23-04-2016 DC74_RS07425 0acb1841a641ebce6ea39da07f9be22d 318 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 14 300 4.0E-30 T 23-04-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD DC74_RS14220 a1c1d879e042bdc0e2e2b36ab2d3d48f 548 Pfam PF13830 Domain of unknown function (DUF4192) 15 337 4.0E-39 T 23-04-2016 IPR025447 Protein of unknown function DUF4192 DC74_RS14220 a1c1d879e042bdc0e2e2b36ab2d3d48f 548 Pfam PF13830 Domain of unknown function (DUF4192) 363 524 1.3E-21 T 23-04-2016 IPR025447 Protein of unknown function DUF4192 DC74_RS14220 a1c1d879e042bdc0e2e2b36ab2d3d48f 548 Gene3D G3DSA:1.25.40.10 288 319 2.5E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS14220 a1c1d879e042bdc0e2e2b36ab2d3d48f 548 Gene3D G3DSA:1.25.40.10 473 541 2.5E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS14220 a1c1d879e042bdc0e2e2b36ab2d3d48f 548 SUPERFAMILY SSF48452 288 321 4.55E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS14220 a1c1d879e042bdc0e2e2b36ab2d3d48f 548 SUPERFAMILY SSF48452 475 537 4.55E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS01520 f5904c3691bb984e7a28fe6363261939 354 PANTHER PTHR24421:SF26 25 354 1.3E-67 T 23-04-2016 DC74_RS01520 f5904c3691bb984e7a28fe6363261939 354 SUPERFAMILY SSF55874 242 354 4.61E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01520 f5904c3691bb984e7a28fe6363261939 354 PANTHER PTHR24421 25 354 1.3E-67 T 23-04-2016 DC74_RS01520 f5904c3691bb984e7a28fe6363261939 354 Gene3D G3DSA:3.30.565.10 251 354 9.7E-4 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS01520 f5904c3691bb984e7a28fe6363261939 354 Pfam PF07730 Histidine kinase 155 218 2.1E-12 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS07450 81646c600a07d7c4ef8246d1b0dcfeb7 251 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 99 121 - T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS07450 81646c600a07d7c4ef8246d1b0dcfeb7 251 Pfam PF01066 CDP-alcohol phosphatidyltransferase 54 121 3.8E-9 T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS33430 8ee0359ea7b603ba6896bdaf1c3a6e6c 110 Pfam PF04248 Domain of unknown function (DUF427) 17 105 2.1E-33 T 23-04-2016 IPR007361 Domain of unknown function DUF427 DC74_RS33430 8ee0359ea7b603ba6896bdaf1c3a6e6c 110 PANTHER PTHR34310 5 105 3.0E-36 T 23-04-2016 DC74_RS29390 48d14e88b303232a687c75d2a2d6d9ba 289 PANTHER PTHR30319 1 275 4.1E-68 T 23-04-2016 DC74_RS29390 48d14e88b303232a687c75d2a2d6d9ba 289 Gene3D G3DSA:1.10.10.10 44 89 2.8E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS29390 48d14e88b303232a687c75d2a2d6d9ba 289 Pfam PF08223 PaaX-like protein C-terminal domain 108 269 2.8E-50 T 23-04-2016 IPR013225 PaaX-like, C-terminal UniPathway: UPA00930 DC74_RS29390 48d14e88b303232a687c75d2a2d6d9ba 289 PIRSF PIRSF020623 1 288 2.1E-80 T 23-04-2016 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 UniPathway: UPA00930 DC74_RS29390 48d14e88b303232a687c75d2a2d6d9ba 289 Pfam PF07848 PaaX-like protein 10 86 1.6E-16 T 23-04-2016 IPR012906 PaaX-like, N-terminal UniPathway: UPA00930 DC74_RS29390 48d14e88b303232a687c75d2a2d6d9ba 289 PANTHER PTHR30319:SF1 1 275 4.1E-68 T 23-04-2016 DC74_RS09310 efb39549344d19d171eee3b55dcefe35 172 SUPERFAMILY SSF54427 22 164 1.76E-34 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS09310 efb39549344d19d171eee3b55dcefe35 172 Pfam PF13577 SnoaL-like domain 24 146 2.6E-28 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS09310 efb39549344d19d171eee3b55dcefe35 172 Gene3D G3DSA:3.10.450.50 19 161 4.1E-33 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS37470 14539f087b1f5558d2c791c0e351dbc2 212 Gene3D G3DSA:3.40.630.30 142 203 5.5E-5 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS37470 14539f087b1f5558d2c791c0e351dbc2 212 SUPERFAMILY SSF55729 71 204 5.31E-5 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS09270 ebb24a70302e1557888a85068cc95be3 462 Pfam PF00860 Permease family 31 404 6.3E-67 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS09270 ebb24a70302e1557888a85068cc95be3 462 PANTHER PTHR11119 19 422 1.3E-135 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 DC74_RS09270 ebb24a70302e1557888a85068cc95be3 462 PANTHER PTHR11119:SF49 19 422 1.3E-135 T 23-04-2016 DC74_RS36130 6990f48a18a757740c595197758b45ce 336 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 22 329 9.716 T 23-04-2016 IPR002729 CRISPR-associated protein Cas1 DC74_RS36130 6990f48a18a757740c595197758b45ce 336 Pfam PF01867 CRISPR associated protein Cas1 28 127 1.8E-7 T 23-04-2016 IPR002729 CRISPR-associated protein Cas1 DC74_RS36130 6990f48a18a757740c595197758b45ce 336 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 13 278 1.0E-100 T 23-04-2016 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype DC74_RS19375 9a49b95d61fa2ffcb8a19fbec9550b8a 397 Pfam PF01139 tRNA-splicing ligase RtcB 29 397 2.9E-131 T 23-04-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 DC74_RS19375 9a49b95d61fa2ffcb8a19fbec9550b8a 397 PANTHER PTHR11118:SF3 6 397 7.3E-184 T 23-04-2016 DC74_RS19375 9a49b95d61fa2ffcb8a19fbec9550b8a 397 PANTHER PTHR11118 6 397 7.3E-184 T 23-04-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 DC74_RS19375 9a49b95d61fa2ffcb8a19fbec9550b8a 397 SUPERFAMILY SSF103365 11 397 7.19E-130 T 23-04-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 DC74_RS40685 390457ebb97eb0e48b9713daaa738e14 428 Pfam PF13360 PQQ-like domain 108 398 3.2E-13 T 23-04-2016 IPR002372 Pyrrolo-quinoline quinone repeat DC74_RS40685 390457ebb97eb0e48b9713daaa738e14 428 SMART SM00564 368 399 16.0 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40685 390457ebb97eb0e48b9713daaa738e14 428 SMART SM00564 277 307 440.0 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40685 390457ebb97eb0e48b9713daaa738e14 428 SMART SM00564 325 356 2.9 T 23-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DC74_RS40685 390457ebb97eb0e48b9713daaa738e14 428 Gene3D G3DSA:2.140.10.10 319 403 2.3E-11 T 23-04-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain DC74_RS40685 390457ebb97eb0e48b9713daaa738e14 428 Gene3D G3DSA:2.140.10.10 181 311 8.8E-8 T 23-04-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain DC74_RS40685 390457ebb97eb0e48b9713daaa738e14 428 SUPERFAMILY SSF50998 194 402 5.49E-14 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS28360 d169b74d455dd06486f9be3c010a4b0d 828 Gene3D G3DSA:3.40.50.300 410 499 7.1E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28360 d169b74d455dd06486f9be3c010a4b0d 828 Gene3D G3DSA:3.40.50.300 611 756 7.1E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS28360 d169b74d455dd06486f9be3c010a4b0d 828 SUPERFAMILY SSF52540 403 748 6.55E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS02625 2c838e14c08acb51445068de29eb7cf4 185 SUPERFAMILY SSF109854 5 179 1.31E-38 T 23-04-2016 DC74_RS02625 2c838e14c08acb51445068de29eb7cf4 185 Pfam PF04978 Protein of unknown function (DUF664) 26 180 7.6E-46 T 23-04-2016 IPR007061 Protein of unknown function DUF664 DC74_RS02625 2c838e14c08acb51445068de29eb7cf4 185 Gene3D G3DSA:1.20.120.450 7 182 1.0E-40 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS16285 57752ea05b25212a87ae2a204e778ea4 106 PANTHER PTHR30561:SF0 1 106 1.4E-48 T 23-04-2016 DC74_RS16285 57752ea05b25212a87ae2a204e778ea4 106 PANTHER PTHR30561 1 106 1.4E-48 T 23-04-2016 DC74_RS16285 57752ea05b25212a87ae2a204e778ea4 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 3.0E-26 T 23-04-2016 IPR000390 Small multidrug resistance protein family GO:0016021 DC74_RS16285 57752ea05b25212a87ae2a204e778ea4 106 SUPERFAMILY SSF103481 5 104 2.62E-17 T 23-04-2016 DC74_RS33290 485906ec903c010d9671a09bf3af8381 300 Pfam PF00884 Sulfatase 42 277 9.1E-8 T 23-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 DC74_RS33290 485906ec903c010d9671a09bf3af8381 300 Gene3D G3DSA:3.40.720.10 43 279 2.9E-12 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 DC74_RS33290 485906ec903c010d9671a09bf3af8381 300 SUPERFAMILY SSF53649 42 291 1.42E-20 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS26295 658faa1b161991daafa5417b3ee95390 382 SUPERFAMILY SSF53850 86 299 8.36E-20 T 23-04-2016 DC74_RS26295 658faa1b161991daafa5417b3ee95390 382 Gene3D G3DSA:3.40.190.10 188 294 2.5E-6 T 23-04-2016 DC74_RS26295 658faa1b161991daafa5417b3ee95390 382 Pfam PF09084 NMT1/THI5 like 96 254 1.2E-8 T 23-04-2016 IPR015168 SsuA/THI5-like DC74_RS24745 02b91064b4c4429e991e2ac435b7223a 247 Pfam PF13714 Phosphoenolpyruvate phosphomutase 10 239 5.2E-66 T 23-04-2016 DC74_RS24745 02b91064b4c4429e991e2ac435b7223a 247 Gene3D G3DSA:3.20.20.60 6 223 1.6E-60 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS24745 02b91064b4c4429e991e2ac435b7223a 247 SUPERFAMILY SSF51621 6 243 9.42E-52 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS24745 02b91064b4c4429e991e2ac435b7223a 247 PANTHER PTHR21631:SF18 7 223 1.1E-54 T 23-04-2016 DC74_RS24745 02b91064b4c4429e991e2ac435b7223a 247 PANTHER PTHR21631 7 223 1.1E-54 T 23-04-2016 DC74_RS38485 a6df1c07294a05325bbb6bba5ded8a81 332 Gene3D G3DSA:3.75.10.10 1 328 2.4E-126 T 23-04-2016 DC74_RS38485 a6df1c07294a05325bbb6bba5ded8a81 332 PANTHER PTHR31377:SF0 1 332 3.4E-127 T 23-04-2016 DC74_RS38485 a6df1c07294a05325bbb6bba5ded8a81 332 SUPERFAMILY SSF55909 1 327 3.75E-121 T 23-04-2016 DC74_RS38485 a6df1c07294a05325bbb6bba5ded8a81 332 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 1 326 3.3E-113 T 23-04-2016 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 DC74_RS38485 a6df1c07294a05325bbb6bba5ded8a81 332 PANTHER PTHR31377 1 332 3.4E-127 T 23-04-2016 DC74_RS04365 5c82f15c66d96429d36e7926eb0f5f0c 530 Pfam PF00083 Sugar (and other) transporter 59 489 1.6E-49 T 23-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DC74_RS04365 5c82f15c66d96429d36e7926eb0f5f0c 530 ProSitePatterns PS00216 Sugar transport proteins signature 1. 356 373 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS04365 5c82f15c66d96429d36e7926eb0f5f0c 530 PANTHER PTHR23508 9 504 6.7E-245 T 23-04-2016 DC74_RS04365 5c82f15c66d96429d36e7926eb0f5f0c 530 Gene3D G3DSA:1.20.1250.20 54 262 7.6E-30 T 23-04-2016 DC74_RS04365 5c82f15c66d96429d36e7926eb0f5f0c 530 Gene3D G3DSA:1.20.1250.20 299 485 1.6E-21 T 23-04-2016 DC74_RS04365 5c82f15c66d96429d36e7926eb0f5f0c 530 PANTHER PTHR23508:SF17 9 504 6.7E-245 T 23-04-2016 DC74_RS04365 5c82f15c66d96429d36e7926eb0f5f0c 530 ProSitePatterns PS00217 Sugar transport proteins signature 2. 166 191 - T 23-04-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DC74_RS04365 5c82f15c66d96429d36e7926eb0f5f0c 530 SUPERFAMILY SSF103473 43 488 7.32E-72 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS33385 557eae5d2ccc548cad8a5c3ac2c21044 168 Gene3D G3DSA:1.10.260.40 54 132 8.7E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS33385 557eae5d2ccc548cad8a5c3ac2c21044 168 Pfam PF01381 Helix-turn-helix 47 90 2.0E-6 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS33385 557eae5d2ccc548cad8a5c3ac2c21044 168 SUPERFAMILY SSF47413 54 95 4.44E-6 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS16050 27b99b43b4c87760a14ece2b2a83383b 208 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 25 134 4.9E-5 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal DC74_RS38255 56df83994161607e98528e5e0bcc5751 381 PANTHER PTHR13789 4 376 6.0E-133 T 23-04-2016 DC74_RS38255 56df83994161607e98528e5e0bcc5751 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 5.3E-18 T 23-04-2016 DC74_RS38255 56df83994161607e98528e5e0bcc5751 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 5.3E-18 T 23-04-2016 DC74_RS38255 56df83994161607e98528e5e0bcc5751 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 5.3E-18 T 23-04-2016 DC74_RS38255 56df83994161607e98528e5e0bcc5751 381 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 5.3E-18 T 23-04-2016 DC74_RS38255 56df83994161607e98528e5e0bcc5751 381 PANTHER PTHR13789:SF174 4 376 6.0E-133 T 23-04-2016 DC74_RS38255 56df83994161607e98528e5e0bcc5751 381 Pfam PF01494 FAD binding domain 147 340 6.8E-14 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS38255 56df83994161607e98528e5e0bcc5751 381 Gene3D G3DSA:3.50.50.60 6 175 3.5E-35 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38255 56df83994161607e98528e5e0bcc5751 381 Gene3D G3DSA:3.50.50.60 276 356 3.5E-35 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38255 56df83994161607e98528e5e0bcc5751 381 SUPERFAMILY SSF51905 274 372 5.49E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS38255 56df83994161607e98528e5e0bcc5751 381 SUPERFAMILY SSF51905 6 170 5.49E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS17755 3844d77cf4726421e91a2d313f60522b 65 Pfam PF04149 Domain of unknown function (DUF397) 7 62 2.2E-18 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS26745 6378cc4d641684e39f65fd60b2a74e94 133 Pfam PF05331 Protein of unknown function (DUF742) 13 133 6.8E-41 T 23-04-2016 IPR007995 Protein of unknown function DUF742 DC74_RS26745 6378cc4d641684e39f65fd60b2a74e94 133 PANTHER PTHR36221 13 133 2.1E-34 T 23-04-2016 DC74_RS25465 93738b931c469f4b51318fb7a4d91b60 114 Pfam PF02643 Uncharacterized ACR, COG1430 19 112 1.4E-14 T 23-04-2016 IPR003795 Protein of unknown function DUF192 DC74_RS17350 54d2bb0ca649b6a644a8c276f5f2dabe 200 PANTHER PTHR37163 1 187 3.0E-50 T 23-04-2016 DC74_RS17350 54d2bb0ca649b6a644a8c276f5f2dabe 200 Pfam PF04417 Protein of unknown function (DUF501) 36 156 1.4E-35 T 23-04-2016 IPR007511 Protein of unknown function DUF501 DC74_RS17350 54d2bb0ca649b6a644a8c276f5f2dabe 200 PANTHER PTHR37163:SF1 1 187 3.0E-50 T 23-04-2016 DC74_RS29385 327ca6897b4b4d8fa0234311dd1425e9 264 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 117 196 2.2E-6 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS29385 327ca6897b4b4d8fa0234311dd1425e9 264 Pfam PF13419 Haloacid dehalogenase-like hydrolase 23 203 2.4E-28 T 23-04-2016 IPR023214 HAD-like domain DC74_RS29385 327ca6897b4b4d8fa0234311dd1425e9 264 Gene3D G3DSA:3.40.50.1000 17 33 2.5E-34 T 23-04-2016 IPR023214 HAD-like domain DC74_RS29385 327ca6897b4b4d8fa0234311dd1425e9 264 Gene3D G3DSA:3.40.50.1000 107 233 2.5E-34 T 23-04-2016 IPR023214 HAD-like domain DC74_RS29385 327ca6897b4b4d8fa0234311dd1425e9 264 PANTHER PTHR18901 19 257 1.9E-38 T 23-04-2016 DC74_RS29385 327ca6897b4b4d8fa0234311dd1425e9 264 SUPERFAMILY SSF56784 18 232 5.97E-47 T 23-04-2016 IPR023214 HAD-like domain DC74_RS29385 327ca6897b4b4d8fa0234311dd1425e9 264 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 116 129 2.4E-5 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS29385 327ca6897b4b4d8fa0234311dd1425e9 264 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 163 2.4E-5 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS29385 327ca6897b4b4d8fa0234311dd1425e9 264 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 19 30 2.4E-5 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS10260 01baf4d75b42e3b5d98f6b5690d40730 99 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 7 50 5.0E-16 T 23-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 DC74_RS10260 01baf4d75b42e3b5d98f6b5690d40730 99 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 81 18.257 T 23-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 DC74_RS10260 01baf4d75b42e3b5d98f6b5690d40730 99 Pfam PF02416 mttA/Hcf106 family 7 54 1.3E-15 T 23-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 SUPERFAMILY SSF54909 74 153 5.36E-16 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 SUPERFAMILY SSF46785 12 66 5.12E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 Pfam PF13404 AsnC-type helix-turn-helix domain 12 52 6.6E-15 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 SMART SM00344 12 116 9.1E-36 T 23-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 Gene3D G3DSA:3.30.70.920 65 151 1.8E-17 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 PANTHER PTHR30154:SF2 4 157 2.3E-49 T 23-04-2016 DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 23-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 Pfam PF01037 Lrp/AsnC ligand binding domain 77 146 2.8E-16 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 Gene3D G3DSA:1.10.10.10 11 59 1.6E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 2.5E-11 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 2.5E-11 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 2.5E-11 T 23-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 DC74_RS28280 f0a408ac26bf59294fb5bd6d3b39528f 157 PANTHER PTHR30154 4 157 2.3E-49 T 23-04-2016 DC74_RS37555 457a3c54b0e34530a195962935f853b5 343 Gene3D G3DSA:1.20.140.10 189 321 1.4E-16 T 23-04-2016 DC74_RS37555 457a3c54b0e34530a195962935f853b5 343 SUPERFAMILY SSF47203 188 322 5.64E-21 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS37555 457a3c54b0e34530a195962935f853b5 343 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 188 293 1.5E-12 T 23-04-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DC74_RS38615 456813460bdc26349e11507d17dc2b5d 97 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 97 5.2E-23 T 23-04-2016 DC74_RS38615 456813460bdc26349e11507d17dc2b5d 97 SUPERFAMILY SSF54292 21 97 1.62E-15 T 23-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DC74_RS00010 b050fe82f5c43c568e46b44b4912cbbf 427 Gene3D G3DSA:3.40.50.300 204 321 4.2E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00010 b050fe82f5c43c568e46b44b4912cbbf 427 SUPERFAMILY SSF52540 203 361 4.09E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS00010 b050fe82f5c43c568e46b44b4912cbbf 427 Pfam PF13401 AAA domain 215 328 1.2E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS14890 6c30d11bb8a4a354b7723ef2b724c325 493 SUPERFAMILY SSF55874 217 343 4.06E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS14890 6c30d11bb8a4a354b7723ef2b724c325 493 Gene3D G3DSA:3.30.565.10 210 343 1.5E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS28160 ceffd543fdc378891c2b2fee444060d6 102 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 1.6E-52 T 23-04-2016 IPR019592 Protein of unknown function DUF2469 DC74_RS03775 a0c48be1266340daa9b5bff82e5b8d00 126 SMART SM00287 46 115 0.0093 T 23-04-2016 IPR003646 SH3-like domain, bacterial-type DC74_RS03775 a0c48be1266340daa9b5bff82e5b8d00 126 Pfam PF08239 Bacterial SH3 domain 54 112 2.0E-10 T 23-04-2016 IPR003646 SH3-like domain, bacterial-type DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 Gene3D G3DSA:3.50.50.60 267 307 1.1E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 Gene3D G3DSA:3.50.50.60 2 157 1.1E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 PANTHER PTHR13789 1 417 8.7E-88 T 23-04-2016 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 PANTHER PTHR13789:SF90 1 417 8.7E-88 T 23-04-2016 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 Pfam PF01494 FAD binding domain 3 334 3.6E-87 T 23-04-2016 IPR002938 FAD-binding domain GO:0071949 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 SUPERFAMILY SSF51905 4 167 5.19E-58 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 SUPERFAMILY SSF51905 256 346 5.19E-58 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 269 284 1.6E-47 T 23-04-2016 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 336 1.6E-47 T 23-04-2016 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 300 1.6E-47 T 23-04-2016 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.6E-47 T 23-04-2016 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 1.6E-47 T 23-04-2016 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 320 1.6E-47 T 23-04-2016 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 Gene3D G3DSA:3.30.9.10 158 262 8.5E-7 T 23-04-2016 DC74_RS32285 81a99da3f00098ba4c69a45150afd537 492 Gene3D G3DSA:3.30.9.10 317 337 8.5E-7 T 23-04-2016 DC74_RS27575 561b3ec3063457942f173ecf6265c1bd 318 SUPERFAMILY SSF51726 41 314 4.19E-33 T 23-04-2016 DC74_RS27575 561b3ec3063457942f173ecf6265c1bd 318 Gene3D G3DSA:3.20.20.210 64 315 3.3E-16 T 23-04-2016 DC74_RS27575 561b3ec3063457942f173ecf6265c1bd 318 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 22 311 1.7E-13 T 23-04-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 DC74_RS36085 6eb2df9d0ce9e51a3f98c1dc8be46a8c 443 Pfam PF14025 Protein of unknown function (DUF4241) 247 421 1.9E-24 T 23-04-2016 IPR025335 Protein of unknown function DUF4241 DC74_RS23520 95d7cfeb62eb03139fef61b67ab07e0d 498 Gene3D G3DSA:3.40.50.2000 17 284 1.6E-58 T 23-04-2016 DC74_RS23520 95d7cfeb62eb03139fef61b67ab07e0d 498 Pfam PF00982 Glycosyltransferase family 20 18 497 1.1E-97 T 23-04-2016 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 DC74_RS23520 95d7cfeb62eb03139fef61b67ab07e0d 498 SUPERFAMILY SSF53756 18 497 6.91E-107 T 23-04-2016 DC74_RS23520 95d7cfeb62eb03139fef61b67ab07e0d 498 PANTHER PTHR10788 17 498 3.3E-111 T 23-04-2016 DC74_RS23520 95d7cfeb62eb03139fef61b67ab07e0d 498 PANTHER PTHR10788:SF6 17 498 3.3E-111 T 23-04-2016 DC74_RS23520 95d7cfeb62eb03139fef61b67ab07e0d 498 Gene3D G3DSA:3.40.50.2000 285 477 4.2E-56 T 23-04-2016 DC74_RS03155 23ac98188c96f6f82285efcda3cdfba8 300 Pfam PF13354 Beta-lactamase enzyme family 28 268 1.3E-40 T 23-04-2016 DC74_RS03155 23ac98188c96f6f82285efcda3cdfba8 300 SUPERFAMILY SSF56601 6 152 2.6E-29 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS03155 23ac98188c96f6f82285efcda3cdfba8 300 SUPERFAMILY SSF56601 184 273 2.6E-29 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS03155 23ac98188c96f6f82285efcda3cdfba8 300 Gene3D G3DSA:3.40.710.10 10 152 3.8E-41 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS03155 23ac98188c96f6f82285efcda3cdfba8 300 Gene3D G3DSA:3.40.710.10 184 299 3.8E-41 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like DC74_RS03155 23ac98188c96f6f82285efcda3cdfba8 300 PANTHER PTHR35333 5 300 8.9E-27 T 23-04-2016 DC74_RS03410 724f3377584c263e6f39562b3abd9158 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 95 9.4E-10 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS03410 724f3377584c263e6f39562b3abd9158 142 Gene3D G3DSA:2.30.110.10 13 138 1.4E-21 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS03410 724f3377584c263e6f39562b3abd9158 142 SUPERFAMILY SSF50475 9 138 2.06E-20 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS13175 503015734b8cb98178451df353417bb1 298 SUPERFAMILY SSF69593 95 206 1.16E-17 T 23-04-2016 DC74_RS13175 503015734b8cb98178451df353417bb1 298 Pfam PF01553 Acyltransferase 93 204 2.7E-14 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS13175 503015734b8cb98178451df353417bb1 298 PANTHER PTHR10434 55 215 1.1E-28 T 23-04-2016 DC74_RS13175 503015734b8cb98178451df353417bb1 298 PANTHER PTHR10434 234 268 1.1E-28 T 23-04-2016 DC74_RS13175 503015734b8cb98178451df353417bb1 298 PANTHER PTHR10434:SF8 55 215 1.1E-28 T 23-04-2016 DC74_RS13175 503015734b8cb98178451df353417bb1 298 PANTHER PTHR10434:SF8 234 268 1.1E-28 T 23-04-2016 DC74_RS13175 503015734b8cb98178451df353417bb1 298 SMART SM00563 95 207 2.5E-19 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 DC74_RS32690 b71b5704c296daaedc2783b461275841 419 PANTHER PTHR23132 104 365 5.0E-12 T 23-04-2016 DC74_RS32690 b71b5704c296daaedc2783b461275841 419 Pfam PF13535 ATP-grasp domain 152 293 1.6E-9 T 23-04-2016 DC74_RS32690 b71b5704c296daaedc2783b461275841 419 Gene3D G3DSA:3.30.470.20 113 300 4.7E-10 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 DC74_RS32690 b71b5704c296daaedc2783b461275841 419 SUPERFAMILY SSF56059 105 318 6.54E-28 T 23-04-2016 DC74_RS10530 7e31f8ad6d9112310f09db7eb9712cbd 230 Gene3D G3DSA:3.40.50.1000 97 229 2.9E-35 T 23-04-2016 IPR023214 HAD-like domain DC74_RS10530 7e31f8ad6d9112310f09db7eb9712cbd 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 196 1.3E-11 T 23-04-2016 IPR023214 HAD-like domain DC74_RS10530 7e31f8ad6d9112310f09db7eb9712cbd 230 SUPERFAMILY SSF56784 8 220 6.79E-28 T 23-04-2016 IPR023214 HAD-like domain DC74_RS10530 7e31f8ad6d9112310f09db7eb9712cbd 230 PANTHER PTHR12725 7 211 1.6E-24 T 23-04-2016 DC74_RS10530 7e31f8ad6d9112310f09db7eb9712cbd 230 PANTHER PTHR12725:SF59 7 211 1.6E-24 T 23-04-2016 DC74_RS33375 8f3df024ff0eeb1dd19f353131dc7d80 82 Pfam PF05360 yiaA/B two helix domain 1 51 7.2E-19 T 23-04-2016 IPR008024 YiaAB two helix DC74_RS33375 8f3df024ff0eeb1dd19f353131dc7d80 82 PANTHER PTHR37290:SF1 1 77 1.2E-16 T 23-04-2016 DC74_RS33375 8f3df024ff0eeb1dd19f353131dc7d80 82 PANTHER PTHR37290 1 77 1.2E-16 T 23-04-2016 DC74_RS12090 563ec0981a95383cc2b325b67387a8d8 406 PANTHER PTHR30483:SF20 12 393 5.1E-90 T 23-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 DC74_RS12090 563ec0981a95383cc2b325b67387a8d8 406 PANTHER PTHR30483 12 393 5.1E-90 T 23-04-2016 DC74_RS12090 563ec0981a95383cc2b325b67387a8d8 406 Gene3D G3DSA:3.40.50.2300 33 243 4.6E-55 T 23-04-2016 DC74_RS12090 563ec0981a95383cc2b325b67387a8d8 406 SUPERFAMILY SSF53822 34 393 1.01E-71 T 23-04-2016 IPR028082 Periplasmic binding protein-like I DC74_RS12090 563ec0981a95383cc2b325b67387a8d8 406 Pfam PF13458 Periplasmic binding protein 34 389 3.2E-51 T 23-04-2016 IPR028081 Leucine-binding protein domain DC74_RS13855 828674029b1a0cfe21ed20b1783cd352 378 Pfam PF03824 High-affinity nickel-transport protein 55 341 5.1E-85 T 23-04-2016 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 DC74_RS13855 828674029b1a0cfe21ed20b1783cd352 378 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 57 337 7.5E-112 T 23-04-2016 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 DC74_RS13855 828674029b1a0cfe21ed20b1783cd352 378 PANTHER PTHR31611 8 359 2.0E-86 T 23-04-2016 DC74_RS18495 ce9d48a80dc033424b30c5e0849cbb06 398 PANTHER PTHR14741 84 277 6.7E-32 T 23-04-2016 DC74_RS18495 ce9d48a80dc033424b30c5e0849cbb06 398 Gene3D G3DSA:3.40.50.150 78 175 7.7E-20 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS18495 ce9d48a80dc033424b30c5e0849cbb06 398 Gene3D G3DSA:3.40.50.150 328 346 7.7E-20 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS18495 ce9d48a80dc033424b30c5e0849cbb06 398 SUPERFAMILY SSF53335 68 232 2.37E-27 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS18495 ce9d48a80dc033424b30c5e0849cbb06 398 Pfam PF09445 RNA cap guanine-N2 methyltransferase 103 161 1.7E-7 T 23-04-2016 IPR019012 RNA cap guanine-N2 methyltransferase GO:0001510|GO:0008168|GO:0009452 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- DC74_RS07085 83f037f62a152ee77952b4aa9a7ca2d9 170 Gene3D G3DSA:1.10.10.10 32 165 2.1E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS07085 83f037f62a152ee77952b4aa9a7ca2d9 170 SMART SM00347 50 149 2.4E-14 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS07085 83f037f62a152ee77952b4aa9a7ca2d9 170 PANTHER PTHR33164:SF16 31 166 4.9E-24 T 23-04-2016 DC74_RS07085 83f037f62a152ee77952b4aa9a7ca2d9 170 PANTHER PTHR33164 31 166 4.9E-24 T 23-04-2016 DC74_RS07085 83f037f62a152ee77952b4aa9a7ca2d9 170 Pfam PF01047 MarR family 56 113 4.6E-10 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS07085 83f037f62a152ee77952b4aa9a7ca2d9 170 SUPERFAMILY SSF46785 30 165 5.09E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS26805 1acf4986fd7ebdfaa2c20b979e5cef6a 160 Pfam PF13328 HD domain 24 76 4.3E-8 T 23-04-2016 IPR003607 HD/PDEase domain DC74_RS26805 1acf4986fd7ebdfaa2c20b979e5cef6a 160 SUPERFAMILY SSF109604 19 157 6.28E-21 T 23-04-2016 DC74_RS05160 9b6215b53c32b7e2b6b9ed579a6d2987 170 SUPERFAMILY SSF46785 1 158 6.45E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05160 9b6215b53c32b7e2b6b9ed579a6d2987 170 Gene3D G3DSA:1.10.10.10 1 84 7.1E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS05160 9b6215b53c32b7e2b6b9ed579a6d2987 170 Pfam PF03551 Transcriptional regulator PadR-like family 1 73 3.7E-7 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal DC74_RS19420 71c8a3c093df9b32fb6acefa741814c0 229 Pfam PF14016 Protein of unknown function (DUF4232) 99 221 1.1E-22 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS36390 e8ed38fa95e5f19b1231d6a24521acd6 260 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 90 255 1.7E-6 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS36390 e8ed38fa95e5f19b1231d6a24521acd6 260 SUPERFAMILY SSF56529 6 260 8.55E-70 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS36390 e8ed38fa95e5f19b1231d6a24521acd6 260 PANTHER PTHR30143 1 260 7.2E-85 T 23-04-2016 DC74_RS36390 e8ed38fa95e5f19b1231d6a24521acd6 260 Gene3D G3DSA:3.90.850.10 2 260 4.2E-79 T 23-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 DC74_RS17055 d6f7930396c381fe9b7371cf215c5f28 199 Pfam PF04892 VanZ like family 96 171 2.7E-14 T 23-04-2016 IPR006976 VanZ-like DC74_RS35005 2135d6578c4ec877516afd051594afa9 77 Pfam PF00550 Phosphopantetheine attachment site 7 71 7.8E-10 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS35005 2135d6578c4ec877516afd051594afa9 77 Gene3D G3DSA:1.10.1200.10 4 76 1.1E-15 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS35005 2135d6578c4ec877516afd051594afa9 77 SUPERFAMILY SSF47336 5 75 2.49E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS01945 9981ce7ac927cb11c15fd261a97db8fc 106 Gene3D G3DSA:1.10.1510.10 1 96 1.3E-10 T 23-04-2016 DC74_RS00665 b1c39c884740dc232d23ba4905eb8ac3 231 Gene3D G3DSA:3.90.79.10 4 103 8.1E-10 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS00665 b1c39c884740dc232d23ba4905eb8ac3 231 SUPERFAMILY SSF55811 9 102 1.04E-9 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS32190 26c0da74eff6bc763bc8946c5a91df37 179 SUPERFAMILY SSF55154 5 153 1.33E-14 T 23-04-2016 IPR033469 CYTH-like domain DC74_RS32190 26c0da74eff6bc763bc8946c5a91df37 179 Gene3D G3DSA:2.40.320.10 5 153 2.6E-20 T 23-04-2016 IPR023577 CYTH domain DC74_RS18730 561fb28d1896fc35fd0706e24a80bad1 216 Gene3D G3DSA:3.40.1370.10 58 202 3.0E-50 T 23-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 DC74_RS18730 561fb28d1896fc35fd0706e24a80bad1 216 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 32.591 T 23-04-2016 IPR013005 50S ribosomal protein uL4 DC74_RS18730 561fb28d1896fc35fd0706e24a80bad1 216 SUPERFAMILY SSF52166 1 203 5.89E-74 T 23-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 DC74_RS18730 561fb28d1896fc35fd0706e24a80bad1 216 Pfam PF00573 Ribosomal protein L4/L1 family 17 202 3.7E-63 T 23-04-2016 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 DC74_RS18730 561fb28d1896fc35fd0706e24a80bad1 216 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 202 2.2E-69 T 23-04-2016 IPR013005 50S ribosomal protein uL4 DC74_RS18730 561fb28d1896fc35fd0706e24a80bad1 216 PANTHER PTHR10746 4 200 1.6E-76 T 23-04-2016 IPR013005 50S ribosomal protein uL4 DC74_RS05235 e0df02acdb3c4356fa0e9149b41f744d 317 PANTHER PTHR30465:SF0 5 315 3.6E-73 T 23-04-2016 DC74_RS05235 e0df02acdb3c4356fa0e9149b41f744d 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 313 1.2E-27 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS05235 e0df02acdb3c4356fa0e9149b41f744d 317 SUPERFAMILY SSF161098 93 299 3.53E-13 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS05235 e0df02acdb3c4356fa0e9149b41f744d 317 Gene3D G3DSA:1.10.3720.10 91 311 6.3E-14 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS05235 e0df02acdb3c4356fa0e9149b41f744d 317 PANTHER PTHR30465 5 315 3.6E-73 T 23-04-2016 DC74_RS10900 bb5fb75d5ab379c54f1337d27319085f 634 Gene3D G3DSA:3.50.50.60 11 211 1.4E-5 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS10900 bb5fb75d5ab379c54f1337d27319085f 634 SUPERFAMILY SSF51971 124 241 1.24E-6 T 23-04-2016 DC74_RS10900 bb5fb75d5ab379c54f1337d27319085f 634 SUPERFAMILY SSF51971 8 61 1.24E-6 T 23-04-2016 DC74_RS10900 bb5fb75d5ab379c54f1337d27319085f 634 Pfam PF13454 FAD-NAD(P)-binding 14 192 3.2E-44 T 23-04-2016 DC74_RS23375 158f1b32ca15832b81485887bacbde51 232 SUPERFAMILY SSF89372 17 226 2.88E-8 T 23-04-2016 DC74_RS23375 158f1b32ca15832b81485887bacbde51 232 SMART SM00706 156 190 1.8E-8 T 23-04-2016 IPR006624 Beta-propeller repeat TECPR DC74_RS23375 158f1b32ca15832b81485887bacbde51 232 SMART SM00706 40 74 0.0014 T 23-04-2016 IPR006624 Beta-propeller repeat TECPR DC74_RS23375 158f1b32ca15832b81485887bacbde51 232 SMART SM00706 2 36 5.6E-9 T 23-04-2016 IPR006624 Beta-propeller repeat TECPR DC74_RS23375 158f1b32ca15832b81485887bacbde51 232 SMART SM00706 117 151 0.0014 T 23-04-2016 IPR006624 Beta-propeller repeat TECPR DC74_RS23375 158f1b32ca15832b81485887bacbde51 232 SMART SM00706 79 113 1.3E-8 T 23-04-2016 IPR006624 Beta-propeller repeat TECPR DC74_RS23375 158f1b32ca15832b81485887bacbde51 232 SMART SM00706 194 228 0.0026 T 23-04-2016 IPR006624 Beta-propeller repeat TECPR DC74_RS10965 8a88e3198afd11e503553748b57427d9 72 Pfam PF11720 Peptidase inhibitor I78 family 29 64 1.1E-7 T 23-04-2016 IPR021719 Proteinase inhibitor I78 DC74_RS24245 bd5777b20c8964fe3a9080182f2e4b83 309 Pfam PF11651 P22 coat protein - gene protein 5 1 217 2.3E-26 T 23-04-2016 IPR024659 Major capsid protein Gp5 DC74_RS17475 94f4c833b5cfe93e04499cd3970605f2 186 Pfam PF14433 SUKH-3 immunity protein 20 175 2.6E-39 T 23-04-2016 IPR025850 SUKH-3 immunity protein DC74_RS34155 a1eaaeaf6db4d241c32304e36b1ff337 137 Pfam PF04134 Protein of unknown function, DUF393 13 120 2.3E-21 T 23-04-2016 IPR007263 Protein of unknown function DUF393 DC74_RS34155 a1eaaeaf6db4d241c32304e36b1ff337 137 PANTHER PTHR34290 1 123 4.2E-12 T 23-04-2016 DC74_RS04690 ad0eb0b5aa90bfc3f97b1557a0874c61 161 SUPERFAMILY SSF54427 19 115 3.4E-13 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS04690 ad0eb0b5aa90bfc3f97b1557a0874c61 161 Gene3D G3DSA:3.10.450.50 21 113 2.7E-9 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS32845 bb8fd69822101519dca5e91bb831584f 80 Pfam PF04149 Domain of unknown function (DUF397) 16 69 5.1E-19 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS17595 48b89124be7e02c26ed87bc96619c25b 402 PANTHER PTHR33627:SF1 1 395 9.9E-93 T 23-04-2016 DC74_RS17595 48b89124be7e02c26ed87bc96619c25b 402 PANTHER PTHR33627 1 395 9.9E-93 T 23-04-2016 DC74_RS17595 48b89124be7e02c26ed87bc96619c25b 402 Pfam PF13546 DDE superfamily endonuclease 21 282 5.5E-85 T 23-04-2016 DC74_RS17595 48b89124be7e02c26ed87bc96619c25b 402 SUPERFAMILY SSF53098 30 393 2.5E-40 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS36190 48b89124be7e02c26ed87bc96619c25b 402 PANTHER PTHR33627:SF1 1 395 9.9E-93 T 23-04-2016 DC74_RS36190 48b89124be7e02c26ed87bc96619c25b 402 PANTHER PTHR33627 1 395 9.9E-93 T 23-04-2016 DC74_RS36190 48b89124be7e02c26ed87bc96619c25b 402 Pfam PF13546 DDE superfamily endonuclease 21 282 5.5E-85 T 23-04-2016 DC74_RS36190 48b89124be7e02c26ed87bc96619c25b 402 SUPERFAMILY SSF53098 30 393 2.5E-40 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS30060 48b89124be7e02c26ed87bc96619c25b 402 PANTHER PTHR33627:SF1 1 395 9.9E-93 T 23-04-2016 DC74_RS30060 48b89124be7e02c26ed87bc96619c25b 402 PANTHER PTHR33627 1 395 9.9E-93 T 23-04-2016 DC74_RS30060 48b89124be7e02c26ed87bc96619c25b 402 Pfam PF13546 DDE superfamily endonuclease 21 282 5.5E-85 T 23-04-2016 DC74_RS30060 48b89124be7e02c26ed87bc96619c25b 402 SUPERFAMILY SSF53098 30 393 2.5E-40 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS04050 48b89124be7e02c26ed87bc96619c25b 402 PANTHER PTHR33627:SF1 1 395 9.9E-93 T 23-04-2016 DC74_RS04050 48b89124be7e02c26ed87bc96619c25b 402 PANTHER PTHR33627 1 395 9.9E-93 T 23-04-2016 DC74_RS04050 48b89124be7e02c26ed87bc96619c25b 402 Pfam PF13546 DDE superfamily endonuclease 21 282 5.5E-85 T 23-04-2016 DC74_RS04050 48b89124be7e02c26ed87bc96619c25b 402 SUPERFAMILY SSF53098 30 393 2.5E-40 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 DC74_RS39885 bc8d7fdd62c2752c2582d4db47c1f93a 55 Gene3D G3DSA:3.30.1330.40 2 49 1.7E-7 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS39885 bc8d7fdd62c2752c2582d4db47c1f93a 55 SUPERFAMILY SSF55298 2 49 4.21E-6 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like DC74_RS30340 b29cd867cfc423d4619739f9eb6e4420 373 Pfam PF00772 DnaB-like helicase N terminal domain 194 269 1.8E-7 T 23-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 DC74_RS30340 b29cd867cfc423d4619739f9eb6e4420 373 Pfam PF00772 DnaB-like helicase N terminal domain 22 118 2.2E-12 T 23-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 DC74_RS30340 b29cd867cfc423d4619739f9eb6e4420 373 Gene3D G3DSA:1.10.860.10 194 271 3.1E-8 T 23-04-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal DC74_RS30340 b29cd867cfc423d4619739f9eb6e4420 373 Gene3D G3DSA:1.10.860.10 22 118 1.1E-14 T 23-04-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal DC74_RS30340 b29cd867cfc423d4619739f9eb6e4420 373 PANTHER PTHR30153 2 223 3.6E-30 T 23-04-2016 DC74_RS30340 b29cd867cfc423d4619739f9eb6e4420 373 SUPERFAMILY SSF48024 194 292 3.53E-9 T 23-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 DC74_RS30340 b29cd867cfc423d4619739f9eb6e4420 373 SUPERFAMILY SSF48024 20 125 2.09E-12 T 23-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 DC74_RS08965 56303af7497a5a9c20b84e041fb9ce2a 267 SUPERFAMILY SSF52540 21 257 9.32E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS08965 56303af7497a5a9c20b84e041fb9ce2a 267 PIRSF PIRSF039085 19 263 4.2E-99 T 23-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 DC74_RS08965 56303af7497a5a9c20b84e041fb9ce2a 267 PANTHER PTHR24220 23 263 3.3E-119 T 23-04-2016 DC74_RS08965 56303af7497a5a9c20b84e041fb9ce2a 267 Gene3D G3DSA:3.40.50.300 20 259 2.8E-83 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS08965 56303af7497a5a9c20b84e041fb9ce2a 267 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS08965 56303af7497a5a9c20b84e041fb9ce2a 267 SMART SM00382 48 235 8.0E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS08965 56303af7497a5a9c20b84e041fb9ce2a 267 PANTHER PTHR24220:SF327 23 263 3.3E-119 T 23-04-2016 DC74_RS08965 56303af7497a5a9c20b84e041fb9ce2a 267 Pfam PF00005 ABC transporter 39 187 9.1E-33 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS34535 4b58f5e0cbc1ef5cdc540dd675df797b 281 Pfam PF03756 A-factor biosynthesis hotdog domain 195 225 1.6E-10 T 23-04-2016 IPR005509 A-factor biosynthesis hotdog domain DC74_RS34535 4b58f5e0cbc1ef5cdc540dd675df797b 281 Pfam PF03756 A-factor biosynthesis hotdog domain 1 133 4.6E-19 T 23-04-2016 IPR005509 A-factor biosynthesis hotdog domain DC74_RS34675 47004a888fd05283ec9b664fd7c40c7a 148 Pfam PF08592 Domain of unknown function (DUF1772) 18 146 6.5E-16 T 23-04-2016 IPR013901 Protein of unknown function DUF1772 DC74_RS01290 099f692f9e41db3ee0a2a82a501a7d34 267 PANTHER PTHR36852 1 253 1.9E-52 T 23-04-2016 DC74_RS01290 099f692f9e41db3ee0a2a82a501a7d34 267 PANTHER PTHR36852:SF2 1 253 1.9E-52 T 23-04-2016 DC74_RS01290 099f692f9e41db3ee0a2a82a501a7d34 267 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 6 253 4.8E-48 T 23-04-2016 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 DC74_RS40120 7ee0f511825a8152414db6fb011db6bf 470 Pfam PF00656 Caspase domain 14 222 2.9E-8 T 23-04-2016 DC74_RS40120 7ee0f511825a8152414db6fb011db6bf 470 SUPERFAMILY SSF52129 49 223 1.88E-10 T 23-04-2016 IPR029030 Caspase-like domain DC74_RS06245 cc7487a9ee502ed667742ce4e66a8118 73 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 25 73 6.2E-13 T 23-04-2016 IPR012667 Cobalt transporter subunit CbtB, putative DC74_RS02975 f2a3a0b741c7628c15c4e871e80b29df 120 Pfam PF13564 DoxX-like family 7 109 1.1E-19 T 23-04-2016 IPR032808 DoxX family DC74_RS31955 838016806c532efc55218b72180c6878 702 Gene3D G3DSA:3.40.720.10 161 247 1.6E-11 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 DC74_RS31955 838016806c532efc55218b72180c6878 702 Gene3D G3DSA:3.40.720.10 280 440 1.6E-11 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 DC74_RS31955 838016806c532efc55218b72180c6878 702 SUPERFAMILY SSF53649 362 444 7.85E-12 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS31955 838016806c532efc55218b72180c6878 702 SUPERFAMILY SSF53649 280 333 7.85E-12 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS31955 838016806c532efc55218b72180c6878 702 SUPERFAMILY SSF53649 162 246 7.85E-12 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 DC74_RS31955 838016806c532efc55218b72180c6878 702 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 15 127 7.7E-9 T 23-04-2016 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV DC74_RS31955 838016806c532efc55218b72180c6878 702 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 168 442 5.3E-6 T 23-04-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 DC74_RS26955 9a98a5db2adb25ede8c9ecd5b54edd4c 149 Pfam PF10739 Protein of unknown function (DUF2550) 12 143 1.2E-44 T 23-04-2016 IPR019675 Protein of unknown function DUF2550 DC74_RS31720 bbede9f6ac44145d5315d26480e219d0 219 Gene3D G3DSA:1.10.357.10 13 215 3.1E-30 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS31720 bbede9f6ac44145d5315d26480e219d0 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 7.8E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS31720 bbede9f6ac44145d5315d26480e219d0 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 7.8E-10 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS31720 bbede9f6ac44145d5315d26480e219d0 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 7.0E-15 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS31720 bbede9f6ac44145d5315d26480e219d0 219 SUPERFAMILY SSF46689 12 83 3.88E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS31720 bbede9f6ac44145d5315d26480e219d0 219 PANTHER PTHR30055 3 194 1.6E-21 T 23-04-2016 DC74_RS02515 da412e3356227b4b852c61a8e59e7728 317 PANTHER PTHR18640:SF9 1 316 3.3E-75 T 23-04-2016 DC74_RS02515 da412e3356227b4b852c61a8e59e7728 317 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 5 316 1.2E-86 T 23-04-2016 IPR016833 Putative sodium bile acid cotransporter DC74_RS02515 da412e3356227b4b852c61a8e59e7728 317 PIRSF PIRSF026166 1 317 1.6E-111 T 23-04-2016 IPR016833 Putative sodium bile acid cotransporter DC74_RS02515 da412e3356227b4b852c61a8e59e7728 317 PANTHER PTHR18640 1 316 3.3E-75 T 23-04-2016 IPR016833 Putative sodium bile acid cotransporter DC74_RS36990 f1b3de130cbb6371bbf825e1311a74ab 226 PANTHER PTHR11675:SF55 108 224 1.1E-25 T 23-04-2016 DC74_RS36990 f1b3de130cbb6371bbf825e1311a74ab 226 PANTHER PTHR11675 108 224 1.1E-25 T 23-04-2016 DC74_RS36990 f1b3de130cbb6371bbf825e1311a74ab 226 Gene3D G3DSA:2.80.10.50 101 225 7.6E-39 T 23-04-2016 DC74_RS36990 f1b3de130cbb6371bbf825e1311a74ab 226 SUPERFAMILY SSF50370 96 225 6.55E-38 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS36990 f1b3de130cbb6371bbf825e1311a74ab 226 SMART SM00458 99 225 5.4E-28 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS36990 f1b3de130cbb6371bbf825e1311a74ab 226 Pfam PF00652 Ricin-type beta-trefoil lectin domain 107 222 4.4E-27 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS34670 92f56c094bf2535aa61963526ebfb079 142 Pfam PF14087 Domain of unknown function (DUF4267) 16 121 4.7E-20 T 23-04-2016 IPR025363 Protein of unknown function DUF4267 DC74_RS13345 e4f5f114645b50852ae1ceb8b2722704 277 PANTHER PTHR30294 20 276 2.0E-98 T 23-04-2016 DC74_RS13345 e4f5f114645b50852ae1ceb8b2722704 277 Pfam PF01061 ABC-2 type transporter 29 241 5.6E-35 T 23-04-2016 IPR013525 ABC-2 type transporter GO:0016020 DC74_RS13345 e4f5f114645b50852ae1ceb8b2722704 277 PIRSF PIRSF006648 12 277 4.0E-82 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS13345 e4f5f114645b50852ae1ceb8b2722704 277 PANTHER PTHR30294:SF24 20 276 2.0E-98 T 23-04-2016 DC74_RS01390 a1a87c6fe4ad94603f7338c048441154 236 SUPERFAMILY SSF56037 57 222 2.88E-28 T 23-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 DC74_RS01390 a1a87c6fe4ad94603f7338c048441154 236 PANTHER PTHR39209:SF2 1 215 1.1E-47 T 23-04-2016 DC74_RS01390 a1a87c6fe4ad94603f7338c048441154 236 Pfam PF03483 B3/4 domain 65 196 4.0E-25 T 23-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 DC74_RS01390 a1a87c6fe4ad94603f7338c048441154 236 Gene3D G3DSA:3.50.40.10 62 195 1.4E-18 T 23-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 DC74_RS01390 a1a87c6fe4ad94603f7338c048441154 236 SMART SM00873 63 220 6.9E-10 T 23-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 DC74_RS01390 a1a87c6fe4ad94603f7338c048441154 236 PANTHER PTHR39209 1 215 1.1E-47 T 23-04-2016 DC74_RS24725 f4ffe92d6d02f27b2e6a289ede209c07 293 PANTHER PTHR40761:SF1 1 290 8.4E-60 T 23-04-2016 DC74_RS24725 f4ffe92d6d02f27b2e6a289ede209c07 293 PANTHER PTHR40761 1 290 8.4E-60 T 23-04-2016 DC74_RS24725 f4ffe92d6d02f27b2e6a289ede209c07 293 SUPERFAMILY SSF103481 43 119 1.44E-7 T 23-04-2016 DC74_RS16005 2a6a5fccf0f4ef536107fe7319b786e6 393 PANTHER PTHR12526 12 384 1.5E-65 T 23-04-2016 DC74_RS16005 2a6a5fccf0f4ef536107fe7319b786e6 393 SUPERFAMILY SSF53756 14 380 1.06E-79 T 23-04-2016 DC74_RS16005 2a6a5fccf0f4ef536107fe7319b786e6 393 PANTHER PTHR12526:SF374 12 384 1.5E-65 T 23-04-2016 DC74_RS16005 2a6a5fccf0f4ef536107fe7319b786e6 393 Pfam PF13692 Glycosyl transferases group 1 209 344 1.7E-35 T 23-04-2016 DC74_RS16005 2a6a5fccf0f4ef536107fe7319b786e6 393 Gene3D G3DSA:3.40.50.2000 166 355 2.0E-35 T 23-04-2016 DC74_RS16005 2a6a5fccf0f4ef536107fe7319b786e6 393 Pfam PF13439 Glycosyltransferase Family 4 23 178 2.1E-24 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain DC74_RS23720 beb4e4574e3675ffab616c002e9dfd18 301 Pfam PF11228 Protein of unknown function (DUF3027) 31 256 6.4E-84 T 23-04-2016 IPR021391 Protein of unknown function DUF3027 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 Pfam PF00067 Cytochrome P450 220 389 1.0E-24 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PRINTS PR00359 B-class P450 signature 347 358 1.3E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PRINTS PR00359 B-class P450 signature 86 97 1.3E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PRINTS PR00359 B-class P450 signature 153 168 1.3E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PRINTS PR00359 B-class P450 signature 136 152 1.3E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PRINTS PR00359 B-class P450 signature 196 218 1.3E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PRINTS PR00359 B-class P450 signature 289 316 1.3E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PRINTS PR00359 B-class P450 signature 271 282 1.3E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PRINTS PR00359 B-class P450 signature 338 347 1.3E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PRINTS PR00359 B-class P450 signature 317 332 1.3E-48 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 SUPERFAMILY SSF48264 13 396 1.57E-84 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 Gene3D G3DSA:1.10.630.10 11 396 2.6E-112 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PANTHER PTHR11712 8 394 2.7E-76 T 23-04-2016 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PRINTS PR00385 P450 superfamily signature 271 282 8.5E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PRINTS PR00385 P450 superfamily signature 236 253 8.5E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS04775 5a78be4fa7e3f0688e8e082fd194f0e6 401 PRINTS PR00385 P450 superfamily signature 347 358 8.5E-5 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS03955 58abaa286f77d914c3d71d6282741761 342 Pfam PF01757 Acyltransferase family 1 306 1.4E-18 T 23-04-2016 IPR002656 Acyltransferase 3 GO:0016747 DC74_RS03955 58abaa286f77d914c3d71d6282741761 342 PANTHER PTHR23028 1 330 3.4E-92 T 23-04-2016 DC74_RS03955 58abaa286f77d914c3d71d6282741761 342 PANTHER PTHR23028:SF79 1 330 3.4E-92 T 23-04-2016 DC74_RS24960 941550693093aadfa1cff5dd5fab7b26 255 SUPERFAMILY SSF53474 26 216 2.73E-21 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS24960 941550693093aadfa1cff5dd5fab7b26 255 Gene3D G3DSA:3.40.50.1820 52 216 1.9E-18 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS28000 680bbfd620ee880aba5709b2fb1da6c0 219 Pfam PF02620 Uncharacterized ACR, COG1399 79 196 8.5E-34 T 23-04-2016 IPR003772 Protein of unknown function DUF177 DC74_RS28000 680bbfd620ee880aba5709b2fb1da6c0 219 PANTHER PTHR34374 14 208 1.4E-54 T 23-04-2016 DC74_RS19315 7e64332096401927d96fd19c23cc0ee0 407 Gene3D G3DSA:3.20.20.370 68 374 3.3E-9 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS19315 7e64332096401927d96fd19c23cc0ee0 407 SUPERFAMILY SSF88713 66 116 1.75E-24 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS19315 7e64332096401927d96fd19c23cc0ee0 407 SUPERFAMILY SSF88713 146 375 1.75E-24 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS14680 14a27add1cecce6beeb3cb3fda07d7d7 231 Pfam PF14016 Protein of unknown function (DUF4232) 96 224 1.8E-22 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS30120 9858f6f807776f09af1093528e9854a3 222 Pfam PF01930 Domain of unknown function DUF83 19 195 3.7E-20 T 23-04-2016 IPR022765 Dna2/Cas4, domain of unknown function DUF83 DC74_RS30120 9858f6f807776f09af1093528e9854a3 222 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 18 194 9.3E-26 T 23-04-2016 IPR013343 CRISPR-associated protein Cas4 DC74_RS32645 8750c56dee3758f80bf861515e8ea0b6 260 PANTHER PTHR19288 6 260 2.8E-62 T 23-04-2016 DC74_RS32645 8750c56dee3758f80bf861515e8ea0b6 260 Pfam PF13242 HAD-hyrolase-like 176 250 6.9E-17 T 23-04-2016 DC74_RS32645 8750c56dee3758f80bf861515e8ea0b6 260 SUPERFAMILY SSF56784 7 252 2.23E-47 T 23-04-2016 IPR023214 HAD-like domain DC74_RS32645 8750c56dee3758f80bf861515e8ea0b6 260 Gene3D G3DSA:3.40.50.10410 79 175 1.9E-25 T 23-04-2016 IPR023215 Nitrophenylphosphatase-like domain DC74_RS32645 8750c56dee3758f80bf861515e8ea0b6 260 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 98 1.8E-15 T 23-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA DC74_RS32645 8750c56dee3758f80bf861515e8ea0b6 260 TIGRFAM TIGR01458 HAD-SF-IIA-hyp3: HAD hydrolase, TIGR01458 family 6 255 9.5E-54 T 23-04-2016 IPR006355 HAD-superfamily hydrolase, subfamily IIA, hypothetical 2 DC74_RS32645 8750c56dee3758f80bf861515e8ea0b6 260 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 175 223 1.1E-7 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS32645 8750c56dee3758f80bf861515e8ea0b6 260 Gene3D G3DSA:3.40.50.1000 176 254 1.5E-35 T 23-04-2016 IPR023214 HAD-like domain DC74_RS32645 8750c56dee3758f80bf861515e8ea0b6 260 Gene3D G3DSA:3.40.50.1000 6 78 1.5E-35 T 23-04-2016 IPR023214 HAD-like domain DC74_RS01480 b32355b84bf9a864b5b05c4f3bea5313 322 Pfam PF00805 Pentapeptide repeats (8 copies) 191 222 1.1E-9 T 23-04-2016 IPR001646 Pentapeptide repeat DC74_RS01480 b32355b84bf9a864b5b05c4f3bea5313 322 SUPERFAMILY SSF141571 166 279 5.49E-18 T 23-04-2016 DC74_RS21560 1f983a3e6d1670e1d4db7842e571dc9b 90 Pfam PF04149 Domain of unknown function (DUF397) 5 23 2.8E-7 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS21560 1f983a3e6d1670e1d4db7842e571dc9b 90 Pfam PF04149 Domain of unknown function (DUF397) 27 83 4.0E-21 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS23775 3283b512198fce9bce9c675a63349021 62 SUPERFAMILY SSF47598 3 35 5.08E-5 T 23-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 DC74_RS39785 b720cd7cd482f914e6869a9647840c2b 210 PANTHER PTHR30055 1 209 5.2E-19 T 23-04-2016 DC74_RS39785 b720cd7cd482f914e6869a9647840c2b 210 SUPERFAMILY SSF46689 6 86 3.13E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS39785 b720cd7cd482f914e6869a9647840c2b 210 SUPERFAMILY SSF48498 95 191 2.17E-16 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS39785 b720cd7cd482f914e6869a9647840c2b 210 Gene3D G3DSA:1.10.357.10 7 191 3.8E-30 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS39785 b720cd7cd482f914e6869a9647840c2b 210 Pfam PF16925 Bacterial transcriptional repressor C-terminal 97 178 1.7E-6 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS39785 b720cd7cd482f914e6869a9647840c2b 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.2E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39785 b720cd7cd482f914e6869a9647840c2b 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.2E-5 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS39785 b720cd7cd482f914e6869a9647840c2b 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 62 1.4E-9 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS01770 b62e28660357142daf0be33e77fe46bc 265 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 205 218 - T 23-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 DC74_RS01770 b62e28660357142daf0be33e77fe46bc 265 PANTHER PTHR10584 10 246 3.0E-31 T 23-04-2016 DC74_RS01770 b62e28660357142daf0be33e77fe46bc 265 Gene3D G3DSA:3.40.1190.20 4 261 1.5E-45 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS01770 b62e28660357142daf0be33e77fe46bc 265 Pfam PF00294 pfkB family carbohydrate kinase 3 252 1.8E-33 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS01770 b62e28660357142daf0be33e77fe46bc 265 SUPERFAMILY SSF53613 2 249 4.83E-42 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS09465 2cfa47264096a193aec17f274e33250f 166 Pfam PF01381 Helix-turn-helix 13 69 1.2E-8 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS09465 2cfa47264096a193aec17f274e33250f 166 SUPERFAMILY SSF47413 4 74 4.44E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS09465 2cfa47264096a193aec17f274e33250f 166 Gene3D G3DSA:1.10.260.40 3 75 4.7E-12 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS09465 2cfa47264096a193aec17f274e33250f 166 SMART SM00530 12 69 2.1E-6 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS01765 083469ff3100a20141ea102d5884fc6c 58 Gene3D G3DSA:1.10.1470.10 3 54 9.2E-8 T 23-04-2016 IPR008462 CsbD-like DC74_RS01765 083469ff3100a20141ea102d5884fc6c 58 Pfam PF05532 CsbD-like 3 50 5.5E-11 T 23-04-2016 IPR008462 CsbD-like DC74_RS01765 083469ff3100a20141ea102d5884fc6c 58 SUPERFAMILY SSF69047 3 54 1.7E-6 T 23-04-2016 IPR008462 CsbD-like DC74_RS08890 8c7b3807add2c2f83161d2503b04fe10 427 PANTHER PTHR32308 97 427 2.8E-57 T 23-04-2016 IPR011206 Citrate lyase beta subunit-like DC74_RS08890 8c7b3807add2c2f83161d2503b04fe10 427 SUPERFAMILY SSF51621 99 344 6.38E-12 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS08890 8c7b3807add2c2f83161d2503b04fe10 427 PANTHER PTHR32308:SF0 97 427 2.8E-57 T 23-04-2016 DC74_RS08890 8c7b3807add2c2f83161d2503b04fe10 427 Gene3D G3DSA:3.20.20.60 108 303 5.4E-11 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 DC74_RS37495 7524541d7649a392f809fcba34cfffd8 50 Gene3D G3DSA:3.30.70.20 12 36 3.9E-4 T 23-04-2016 DC74_RS05685 62aa3749d6eec8b5d89e2f35fde3a734 514 PANTHER PTHR11938:SF50 142 468 1.3E-61 T 23-04-2016 DC74_RS05685 62aa3749d6eec8b5d89e2f35fde3a734 514 PIRSF PIRSF006429 4 506 1.9E-144 T 23-04-2016 IPR024188 Glutamate synthase large subunit-like protein DC74_RS05685 62aa3749d6eec8b5d89e2f35fde3a734 514 PANTHER PTHR11938 142 468 1.3E-61 T 23-04-2016 DC74_RS05685 62aa3749d6eec8b5d89e2f35fde3a734 514 SUPERFAMILY SSF51395 10 481 3.61E-117 T 23-04-2016 DC74_RS05685 62aa3749d6eec8b5d89e2f35fde3a734 514 Gene3D G3DSA:3.20.20.70 22 484 2.1E-112 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 DC74_RS05685 62aa3749d6eec8b5d89e2f35fde3a734 514 Pfam PF01645 Conserved region in glutamate synthase 139 454 4.0E-77 T 23-04-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 DC74_RS12965 7031ee83e39bbb19fcb23ee64055b9ec 281 PANTHER PTHR10245:SF7 14 274 7.2E-50 T 23-04-2016 DC74_RS12965 7031ee83e39bbb19fcb23ee64055b9ec 281 SUPERFAMILY SSF47413 12 71 2.76E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS12965 7031ee83e39bbb19fcb23ee64055b9ec 281 Pfam PF13560 Helix-turn-helix domain 18 71 1.1E-6 T 23-04-2016 DC74_RS12965 7031ee83e39bbb19fcb23ee64055b9ec 281 PANTHER PTHR10245 14 274 7.2E-50 T 23-04-2016 DC74_RS12965 7031ee83e39bbb19fcb23ee64055b9ec 281 Gene3D G3DSA:1.10.260.40 14 70 1.8E-6 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS31970 969542b4671a5d8b4f343c61e26b972a 257 SMART SM00530 4 59 3.4E-12 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS31970 969542b4671a5d8b4f343c61e26b972a 257 SUPERFAMILY SSF47413 1 58 6.19E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS31970 969542b4671a5d8b4f343c61e26b972a 257 Gene3D G3DSA:1.10.260.40 1 58 3.9E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS31970 969542b4671a5d8b4f343c61e26b972a 257 PANTHER PTHR10245:SF17 1 187 2.4E-64 T 23-04-2016 DC74_RS31970 969542b4671a5d8b4f343c61e26b972a 257 Pfam PF13560 Helix-turn-helix domain 2 62 5.4E-12 T 23-04-2016 DC74_RS31970 969542b4671a5d8b4f343c61e26b972a 257 PANTHER PTHR10245 1 187 2.4E-64 T 23-04-2016 DC74_RS30590 eba72452d79409aa1241e17b78291026 279 Pfam PF03771 Domain of unknown function (DUF317) 147 207 1.3E-6 T 23-04-2016 IPR005523 Domain of unknown function DUF317 DC74_RS30590 eba72452d79409aa1241e17b78291026 279 Pfam PF03771 Domain of unknown function (DUF317) 51 104 9.9E-12 T 23-04-2016 IPR005523 Domain of unknown function DUF317 DC74_RS15345 af03864ba68deb9ebf22630e1ed9356d 126 SUPERFAMILY SSF52833 2 117 5.97E-27 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS15345 af03864ba68deb9ebf22630e1ed9356d 126 PANTHER PTHR30041 1 124 7.9E-35 T 23-04-2016 DC74_RS15345 af03864ba68deb9ebf22630e1ed9356d 126 Pfam PF03960 ArsC family 54 115 9.6E-11 T 23-04-2016 IPR006660 Arsenate reductase-like DC74_RS15345 af03864ba68deb9ebf22630e1ed9356d 126 Gene3D G3DSA:3.40.30.10 1 119 3.7E-37 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS15345 af03864ba68deb9ebf22630e1ed9356d 126 PANTHER PTHR30041:SF0 1 124 7.9E-35 T 23-04-2016 DC74_RS10445 cb122291fab1e4af90b793b6906521bb 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DC74_RS10445 cb122291fab1e4af90b793b6906521bb 260 Gene3D G3DSA:3.40.50.720 7 251 1.8E-68 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10445 cb122291fab1e4af90b793b6906521bb 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 251 2.0E-50 T 23-04-2016 DC74_RS10445 cb122291fab1e4af90b793b6906521bb 260 SUPERFAMILY SSF51735 8 253 1.51E-65 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS10445 cb122291fab1e4af90b793b6906521bb 260 PANTHER PTHR24321:SF6 7 253 1.5E-46 T 23-04-2016 DC74_RS10445 cb122291fab1e4af90b793b6906521bb 260 PANTHER PTHR24321 7 253 1.5E-46 T 23-04-2016 DC74_RS10445 cb122291fab1e4af90b793b6906521bb 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.1E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10445 cb122291fab1e4af90b793b6906521bb 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.1E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10445 cb122291fab1e4af90b793b6906521bb 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.1E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10445 cb122291fab1e4af90b793b6906521bb 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.1E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS10445 cb122291fab1e4af90b793b6906521bb 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.1E-29 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR DC74_RS33180 cfa0274c6c12cdfc7826b30268511ed3 252 SUPERFAMILY SSF53448 1 244 1.38E-32 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS33180 cfa0274c6c12cdfc7826b30268511ed3 252 PANTHER PTHR22572 2 244 6.3E-59 T 23-04-2016 DC74_RS33180 cfa0274c6c12cdfc7826b30268511ed3 252 PANTHER PTHR22572:SF9 2 244 6.3E-59 T 23-04-2016 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 DC74_RS33180 cfa0274c6c12cdfc7826b30268511ed3 252 Gene3D G3DSA:3.90.550.10 2 245 9.2E-34 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases DC74_RS33180 cfa0274c6c12cdfc7826b30268511ed3 252 Pfam PF00483 Nucleotidyl transferase 3 148 4.2E-12 T 23-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 DC74_RS25265 1cbf22cc04dc4e23ef49e1d740a17ef5 82 Pfam PF06624 Ribosome associated membrane protein RAMP4 21 42 1.2E-4 T 23-04-2016 IPR010580 Stress-associated endoplasmic reticulum protein GO:0005783 DC74_RS23010 9dba7302fd7466b1a74d3d8b824840d3 154 Pfam PF09965 Uncharacterized protein conserved in bacteria (DUF2199) 3 133 5.1E-42 T 23-04-2016 IPR018697 Protein of unknown function DUF2199 DC74_RS13905 0d000a5a24cf047fea6dcec6de7f4875 275 SUPERFAMILY SSF56784 44 233 3.2E-14 T 23-04-2016 IPR023214 HAD-like domain DC74_RS13905 0d000a5a24cf047fea6dcec6de7f4875 275 SUPERFAMILY SSF56784 7 17 3.2E-14 T 23-04-2016 IPR023214 HAD-like domain DC74_RS13905 0d000a5a24cf047fea6dcec6de7f4875 275 Gene3D G3DSA:3.40.50.1000 7 108 6.8E-9 T 23-04-2016 IPR023214 HAD-like domain DC74_RS13905 0d000a5a24cf047fea6dcec6de7f4875 275 Gene3D G3DSA:3.40.50.1000 184 230 6.8E-9 T 23-04-2016 IPR023214 HAD-like domain DC74_RS13905 0d000a5a24cf047fea6dcec6de7f4875 275 PIRSF PIRSF030802 3 243 1.6E-16 T 23-04-2016 IPR024197 Uncharacterised conserved protein UCP030802 DC74_RS10425 2d51b443c72c10ff812e32e8fb28ef77 333 PANTHER PTHR11732:SF241 6 97 1.2E-98 T 23-04-2016 DC74_RS10425 2d51b443c72c10ff812e32e8fb28ef77 333 PANTHER PTHR11732:SF241 115 333 1.2E-98 T 23-04-2016 DC74_RS10425 2d51b443c72c10ff812e32e8fb28ef77 333 PANTHER PTHR11732 6 97 1.2E-98 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS10425 2d51b443c72c10ff812e32e8fb28ef77 333 PANTHER PTHR11732 115 333 1.2E-98 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta DC74_RS10425 2d51b443c72c10ff812e32e8fb28ef77 333 Gene3D G3DSA:3.20.20.100 9 317 2.4E-55 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS10425 2d51b443c72c10ff812e32e8fb28ef77 333 Pfam PF00248 Aldo/keto reductase family 20 313 6.9E-40 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS10425 2d51b443c72c10ff812e32e8fb28ef77 333 SUPERFAMILY SSF51430 9 317 5.37E-61 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain DC74_RS01330 568a7847b39fc95671dbca83ca4f210e 258 Gene3D G3DSA:3.40.50.10320 44 237 6.5E-38 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS01330 568a7847b39fc95671dbca83ca4f210e 258 PANTHER PTHR12993 32 256 4.6E-21 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS01330 568a7847b39fc95671dbca83ca4f210e 258 SUPERFAMILY SSF102588 44 233 7.06E-37 T 23-04-2016 IPR024078 Putative deacetylase LmbE-like domain DC74_RS01330 568a7847b39fc95671dbca83ca4f210e 258 Pfam PF02585 GlcNAc-PI de-N-acetylase 47 173 1.5E-19 T 23-04-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related DC74_RS29950 ecd0fc7e9bd7b215ed245dd1e209d25a 177 Gene3D G3DSA:3.40.50.880 1 176 1.3E-48 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS29950 ecd0fc7e9bd7b215ed245dd1e209d25a 177 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 6 173 3.8E-43 T 23-04-2016 IPR006286 Peptidase C56, PfpI GO:0016798 DC74_RS29950 ecd0fc7e9bd7b215ed245dd1e209d25a 177 PANTHER PTHR11019:SF115 4 177 7.0E-60 T 23-04-2016 DC74_RS29950 ecd0fc7e9bd7b215ed245dd1e209d25a 177 SUPERFAMILY SSF52317 1 175 2.07E-40 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS29950 ecd0fc7e9bd7b215ed245dd1e209d25a 177 PANTHER PTHR11019 4 177 7.0E-60 T 23-04-2016 DC74_RS29950 ecd0fc7e9bd7b215ed245dd1e209d25a 177 Pfam PF01965 DJ-1/PfpI family 2 174 6.5E-46 T 23-04-2016 IPR002818 DJ-1/PfpI DC74_RS26605 dad1f5bf6f5d529d1ca3f94f7fb34f69 131 Gene3D G3DSA:1.20.120.400 15 130 2.5E-50 T 23-04-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 DC74_RS26605 dad1f5bf6f5d529d1ca3f94f7fb34f69 131 TIGRFAM TIGR02753 sodN: superoxide dismutase, Ni 1 130 1.8E-55 T 23-04-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 DC74_RS26605 dad1f5bf6f5d529d1ca3f94f7fb34f69 131 SUPERFAMILY SSF109770 15 130 3.53E-53 T 23-04-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 DC74_RS26605 dad1f5bf6f5d529d1ca3f94f7fb34f69 131 Pfam PF09055 Nickel-containing superoxide dismutase 11 129 7.8E-43 T 23-04-2016 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 DC74_RS19385 2b117971df7526b1e99e39fe867bc2dd 238 Pfam PF12079 Protein of unknown function (DUF3558) 20 150 5.5E-10 T 23-04-2016 IPR024520 Protein of unknown function DUF3558 DC74_RS32465 895b19141eea5b138fd00583dce4e721 498 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 266 376 2.8E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32465 895b19141eea5b138fd00583dce4e721 498 SMART SM00387 262 377 6.3E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32465 895b19141eea5b138fd00583dce4e721 498 Gene3D G3DSA:3.30.565.10 267 377 2.1E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS32465 895b19141eea5b138fd00583dce4e721 498 PANTHER PTHR24423 125 439 1.2E-22 T 23-04-2016 DC74_RS32465 895b19141eea5b138fd00583dce4e721 498 PANTHER PTHR24423 62 82 1.2E-22 T 23-04-2016 DC74_RS32465 895b19141eea5b138fd00583dce4e721 498 PANTHER PTHR24423:SF508 125 439 1.2E-22 T 23-04-2016 DC74_RS32465 895b19141eea5b138fd00583dce4e721 498 PANTHER PTHR24423:SF508 62 82 1.2E-22 T 23-04-2016 DC74_RS32465 895b19141eea5b138fd00583dce4e721 498 SUPERFAMILY SSF55874 255 377 3.01E-15 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS06745 316d07a2881008e0339ac950d5177cfd 181 Gene3D G3DSA:1.10.10.10 121 152 3.9E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS20780 f9a51c83f62037adf661c108ccaf7945 419 SUPERFAMILY SSF103473 17 418 1.83E-23 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS20780 f9a51c83f62037adf661c108ccaf7945 419 PANTHER PTHR23513 1 419 4.8E-90 T 23-04-2016 DC74_RS20780 f9a51c83f62037adf661c108ccaf7945 419 PANTHER PTHR23513:SF11 1 419 4.8E-90 T 23-04-2016 DC74_RS20780 f9a51c83f62037adf661c108ccaf7945 419 Gene3D G3DSA:1.20.1250.20 17 198 5.2E-11 T 23-04-2016 DC74_RS20780 f9a51c83f62037adf661c108ccaf7945 419 Gene3D G3DSA:1.20.1250.20 247 413 1.9E-4 T 23-04-2016 DC74_RS20780 f9a51c83f62037adf661c108ccaf7945 419 Pfam PF07690 Major Facilitator Superfamily 37 379 1.3E-12 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS37005 5c0628c4ca63c10c912e6fdccc54efc3 464 PANTHER PTHR23501 9 456 3.3E-37 T 23-04-2016 DC74_RS37005 5c0628c4ca63c10c912e6fdccc54efc3 464 Gene3D G3DSA:1.20.1250.20 21 201 4.6E-20 T 23-04-2016 DC74_RS37005 5c0628c4ca63c10c912e6fdccc54efc3 464 Gene3D G3DSA:1.20.1250.20 279 453 3.4E-9 T 23-04-2016 DC74_RS37005 5c0628c4ca63c10c912e6fdccc54efc3 464 Pfam PF07690 Major Facilitator Superfamily 34 408 5.6E-24 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS37005 5c0628c4ca63c10c912e6fdccc54efc3 464 SUPERFAMILY SSF103473 20 213 1.13E-36 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS37005 5c0628c4ca63c10c912e6fdccc54efc3 464 SUPERFAMILY SSF103473 259 451 1.13E-36 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS40385 e4f292558da47ae543ed83cf6ab9b580 229 PANTHER PTHR22983 1 204 2.6E-18 T 23-04-2016 DC74_RS40385 e4f292558da47ae543ed83cf6ab9b580 229 PANTHER PTHR22983:SF13 1 204 2.6E-18 T 23-04-2016 DC74_RS33120 e965d1757cc98b87e22885e5a5d83e47 401 Gene3D G3DSA:1.20.1250.20 206 379 3.5E-13 T 23-04-2016 DC74_RS33120 e965d1757cc98b87e22885e5a5d83e47 401 Gene3D G3DSA:1.20.1250.20 5 178 1.8E-25 T 23-04-2016 DC74_RS33120 e965d1757cc98b87e22885e5a5d83e47 401 PANTHER PTHR23501 1 389 4.0E-116 T 23-04-2016 DC74_RS33120 e965d1757cc98b87e22885e5a5d83e47 401 PANTHER PTHR23501:SF4 1 389 4.0E-116 T 23-04-2016 DC74_RS33120 e965d1757cc98b87e22885e5a5d83e47 401 SUPERFAMILY SSF103473 3 378 3.4E-50 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS33120 e965d1757cc98b87e22885e5a5d83e47 401 Pfam PF07690 Major Facilitator Superfamily 8 322 9.9E-36 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS31075 dc48b5cb9be8d26f054ad7748e17cd4b 354 Pfam PF01699 Sodium/calcium exchanger protein 215 345 2.7E-11 T 23-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 DC74_RS31075 dc48b5cb9be8d26f054ad7748e17cd4b 354 Pfam PF01699 Sodium/calcium exchanger protein 3 177 3.6E-12 T 23-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 DC74_RS35820 41a13a6335de8fb9982cd2a0c8efb625 294 Pfam PF03756 A-factor biosynthesis hotdog domain 180 286 2.7E-5 T 23-04-2016 IPR005509 A-factor biosynthesis hotdog domain DC74_RS35820 41a13a6335de8fb9982cd2a0c8efb625 294 Pfam PF03756 A-factor biosynthesis hotdog domain 5 136 1.3E-26 T 23-04-2016 IPR005509 A-factor biosynthesis hotdog domain DC74_RS38655 25dc2a792cd5379f985d1c6dec8f506e 441 SUPERFAMILY SSF159501 14 418 1.49E-72 T 23-04-2016 DC74_RS38655 25dc2a792cd5379f985d1c6dec8f506e 441 PANTHER PTHR31299:SF0 19 419 3.9E-40 T 23-04-2016 DC74_RS38655 25dc2a792cd5379f985d1c6dec8f506e 441 PANTHER PTHR31299 19 419 3.9E-40 T 23-04-2016 DC74_RS38655 25dc2a792cd5379f985d1c6dec8f506e 441 Gene3D G3DSA:3.30.1870.10 71 143 1.4E-12 T 23-04-2016 DC74_RS38655 25dc2a792cd5379f985d1c6dec8f506e 441 Pfam PF05139 Erythromycin esterase 69 413 2.1E-46 T 23-04-2016 IPR007815 Erythromycin esterase GO:0046677 DC74_RS38655 25dc2a792cd5379f985d1c6dec8f506e 441 Gene3D G3DSA:3.40.1660.10 286 419 2.9E-34 T 23-04-2016 DC74_RS38655 25dc2a792cd5379f985d1c6dec8f506e 441 Gene3D G3DSA:3.40.1660.10 14 70 2.9E-34 T 23-04-2016 DC74_RS19575 81b1a91f8cb857de7fa207b71d138024 427 PANTHER PTHR36844 16 401 9.7E-40 T 23-04-2016 DC74_RS19575 81b1a91f8cb857de7fa207b71d138024 427 Pfam PF13367 Protease prsW family 95 297 2.0E-50 T 23-04-2016 IPR026898 Protease PrsW GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS39195 0f2b823a7fe8c89e77f7814d8557d976 373 SUPERFAMILY SSF56524 243 372 2.35E-36 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS39195 0f2b823a7fe8c89e77f7814d8557d976 373 PANTHER PTHR19372 53 373 3.2E-42 T 23-04-2016 DC74_RS39195 0f2b823a7fe8c89e77f7814d8557d976 373 Pfam PF00174 Oxidoreductase molybdopterin binding domain 244 372 3.2E-25 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS39195 0f2b823a7fe8c89e77f7814d8557d976 373 PRINTS PR00407 Eukaryotic molybdopterin domain signature 344 357 3.8E-5 T 23-04-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 DC74_RS39195 0f2b823a7fe8c89e77f7814d8557d976 373 PRINTS PR00407 Eukaryotic molybdopterin domain signature 360 373 3.8E-5 T 23-04-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 DC74_RS39195 0f2b823a7fe8c89e77f7814d8557d976 373 PRINTS PR00407 Eukaryotic molybdopterin domain signature 279 294 3.8E-5 T 23-04-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 DC74_RS39195 0f2b823a7fe8c89e77f7814d8557d976 373 PRINTS PR00407 Eukaryotic molybdopterin domain signature 327 343 3.8E-5 T 23-04-2016 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 DC74_RS39195 0f2b823a7fe8c89e77f7814d8557d976 373 Gene3D G3DSA:3.90.420.10 244 372 3.9E-35 T 23-04-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 DC74_RS39195 0f2b823a7fe8c89e77f7814d8557d976 373 PANTHER PTHR19372:SF2 53 373 3.2E-42 T 23-04-2016 DC74_RS19235 7ea91b4d7707673c740efc82a3627bf3 201 SUPERFAMILY SSF144091 13 187 5.36E-30 T 23-04-2016 DC74_RS19235 7ea91b4d7707673c740efc82a3627bf3 201 PANTHER PTHR22936:SF11 38 191 1.8E-38 T 23-04-2016 DC74_RS19235 7ea91b4d7707673c740efc82a3627bf3 201 PANTHER PTHR22936 38 191 1.8E-38 T 23-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 DC74_RS19235 7ea91b4d7707673c740efc82a3627bf3 201 Gene3D G3DSA:1.20.1540.10 13 184 1.1E-21 T 23-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 DC74_RS19235 7ea91b4d7707673c740efc82a3627bf3 201 Pfam PF01694 Rhomboid family 46 186 2.8E-25 T 23-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 DC74_RS37965 72aa9a8671e9943dc42051d07ac29e07 737 PANTHER PTHR33908 359 503 6.0E-28 T 23-04-2016 DC74_RS37965 72aa9a8671e9943dc42051d07ac29e07 737 PANTHER PTHR33908 56 331 6.0E-28 T 23-04-2016 DC74_RS37965 72aa9a8671e9943dc42051d07ac29e07 737 PANTHER PTHR33908:SF3 359 503 6.0E-28 T 23-04-2016 DC74_RS37965 72aa9a8671e9943dc42051d07ac29e07 737 PANTHER PTHR33908:SF3 56 331 6.0E-28 T 23-04-2016 DC74_RS37965 72aa9a8671e9943dc42051d07ac29e07 737 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 131 285 2.1E-20 T 23-04-2016 DC74_RS25990 2fec2a699c0afcbca13b615a512d08bc 166 PANTHER PTHR33162:SF1 2 166 7.5E-23 T 23-04-2016 DC74_RS25990 2fec2a699c0afcbca13b615a512d08bc 166 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 146 14.167 T 23-04-2016 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 DC74_RS25990 2fec2a699c0afcbca13b615a512d08bc 166 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 2.2E-11 T 23-04-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 DC74_RS25990 2fec2a699c0afcbca13b615a512d08bc 166 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 2.2E-11 T 23-04-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 DC74_RS25990 2fec2a699c0afcbca13b615a512d08bc 166 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 2.2E-11 T 23-04-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 DC74_RS25990 2fec2a699c0afcbca13b615a512d08bc 166 Pfam PF02416 mttA/Hcf106 family 5 29 3.0E-5 T 23-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 DC74_RS25990 2fec2a699c0afcbca13b615a512d08bc 166 PANTHER PTHR33162 2 166 7.5E-23 T 23-04-2016 DC74_RS08375 2b62a483461af4cf5e13021a3331966d 80 Pfam PF04149 Domain of unknown function (DUF397) 23 73 7.2E-10 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS24515 292f22d2f7b797d0097042b19f0f90bd 174 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 12 158 1.6E-38 T 23-04-2016 IPR011747 Conserved hypothetical protein CHP02241 DC74_RS24515 292f22d2f7b797d0097042b19f0f90bd 174 PANTHER PTHR38009 6 160 2.3E-35 T 23-04-2016 DC74_RS24515 292f22d2f7b797d0097042b19f0f90bd 174 Pfam PF06841 T4-like virus tail tube protein gp19 15 157 7.6E-38 T 23-04-2016 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 DC74_RS24515 292f22d2f7b797d0097042b19f0f90bd 174 PANTHER PTHR38009:SF1 6 160 2.3E-35 T 23-04-2016 DC74_RS29160 fd60ca2e79f7bb42f961c73759d4e9ac 153 Pfam PF11292 Protein of unknown function (DUF3093) 4 142 1.1E-44 T 23-04-2016 IPR021443 Protein of unknown function DUF3093 DC74_RS22060 49b8be6ebd24e5d4b37ebb70ded174d7 241 Gene3D G3DSA:3.90.79.10 56 223 4.8E-34 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS22060 49b8be6ebd24e5d4b37ebb70ded174d7 241 PANTHER PTHR12992 7 239 2.1E-36 T 23-04-2016 DC74_RS22060 49b8be6ebd24e5d4b37ebb70ded174d7 241 Pfam PF00293 NUDIX domain 63 181 8.8E-10 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS22060 49b8be6ebd24e5d4b37ebb70ded174d7 241 SUPERFAMILY SSF55811 60 219 2.44E-24 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS03770 f511e166fa2eeacd9785f125245c032e 217 Pfam PF12079 Protein of unknown function (DUF3558) 67 213 5.5E-9 T 23-04-2016 IPR024520 Protein of unknown function DUF3558 DC74_RS00865 fbd5d2b0b154cb56fb5fd9c63eb252da 289 Pfam PF03756 A-factor biosynthesis hotdog domain 20 88 1.0E-5 T 23-04-2016 IPR005509 A-factor biosynthesis hotdog domain DC74_RS00865 fbd5d2b0b154cb56fb5fd9c63eb252da 289 Pfam PF03756 A-factor biosynthesis hotdog domain 145 267 4.8E-11 T 23-04-2016 IPR005509 A-factor biosynthesis hotdog domain DC74_RS16810 5a8fc389ce1eb21f1c2bb0713503194b 256 SUPERFAMILY SSF52540 48 250 9.27E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16810 5a8fc389ce1eb21f1c2bb0713503194b 256 Pfam PF00005 ABC transporter 54 187 1.9E-16 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DC74_RS16810 5a8fc389ce1eb21f1c2bb0713503194b 256 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DC74_RS16810 5a8fc389ce1eb21f1c2bb0713503194b 256 PANTHER PTHR24220 34 252 1.9E-85 T 23-04-2016 DC74_RS16810 5a8fc389ce1eb21f1c2bb0713503194b 256 Gene3D G3DSA:3.40.50.300 48 252 7.9E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16810 5a8fc389ce1eb21f1c2bb0713503194b 256 PANTHER PTHR24220:SF117 34 252 1.9E-85 T 23-04-2016 DC74_RS16810 5a8fc389ce1eb21f1c2bb0713503194b 256 SMART SM00382 62 253 5.0E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain DC74_RS36115 bae113de99a319190064ab0e80f70273 406 Pfam PF09344 CT1975-like protein 6 383 4.8E-128 T 23-04-2016 IPR010148 CRISPR-associated protein, CT1975 DC74_RS36115 bae113de99a319190064ab0e80f70273 406 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 5 349 6.4E-88 T 23-04-2016 IPR010148 CRISPR-associated protein, CT1975 DC74_RS38800 a2b1a65954676bf3e2c8390e4b3452b1 334 SUPERFAMILY SSF56112 26 295 2.86E-14 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS21035 40eb82032ac3717c796ec1761fb265ef 298 Gene3D G3DSA:3.20.20.30 19 291 1.3E-59 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS21035 40eb82032ac3717c796ec1761fb265ef 298 PANTHER PTHR30011:SF14 19 244 1.7E-60 T 23-04-2016 DC74_RS21035 40eb82032ac3717c796ec1761fb265ef 298 SUPERFAMILY SSF51679 18 290 3.53E-55 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS21035 40eb82032ac3717c796ec1761fb265ef 298 Pfam PF00296 Luciferase-like monooxygenase 19 236 8.7E-45 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 DC74_RS21035 40eb82032ac3717c796ec1761fb265ef 298 PANTHER PTHR30011 19 244 1.7E-60 T 23-04-2016 DC74_RS21250 d38ae7f49a3053a6eabace1f1dd53ea8 323 PANTHER PTHR37826 60 323 1.2E-46 T 23-04-2016 DC74_RS21250 d38ae7f49a3053a6eabace1f1dd53ea8 323 PANTHER PTHR37826:SF1 60 323 1.2E-46 T 23-04-2016 DC74_RS31425 1d2e5d30a1f7be26587ff996d1f3e170 517 PANTHER PTHR30618:SF6 3 473 1.5E-188 T 23-04-2016 DC74_RS31425 1d2e5d30a1f7be26587ff996d1f3e170 517 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 23 441 4.9E-90 T 23-04-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 DC74_RS31425 1d2e5d30a1f7be26587ff996d1f3e170 517 PANTHER PTHR30618 3 473 1.5E-188 T 23-04-2016 DC74_RS00120 5ef1cf725f072b9a2ef5762a55952493 151 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 11 147 8.2E-26 T 23-04-2016 IPR011747 Conserved hypothetical protein CHP02241 DC74_RS00120 5ef1cf725f072b9a2ef5762a55952493 151 PANTHER PTHR38009 5 150 2.3E-13 T 23-04-2016 DC74_RS00120 5ef1cf725f072b9a2ef5762a55952493 151 Pfam PF06841 T4-like virus tail tube protein gp19 15 146 2.9E-28 T 23-04-2016 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 DC74_RS34490 8d628b6d6a2ed3f4af9f4ff15aa33e9f 138 Pfam PF11387 Protein of unknown function (DUF2795) 81 124 3.5E-9 T 23-04-2016 IPR021527 Protein of unknown function DUF2795 DC74_RS23640 46f29bd35064ccee87b90112a37e8460 432 Pfam PF09594 Protein of unknown function (DUF2029) 83 316 1.1E-50 T 23-04-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 DC74_RS33860 c2b2c47134d0b3c00eb7344fcc296c4a 419 Pfam PF09992 Phosphodiester glycosidase 241 416 1.1E-24 T 23-04-2016 IPR018711 Phosphodiester glycosidase DC74_RS36625 082421e3c7be596638f3cbe7e673084c 88 Pfam PF04226 Transglycosylase associated protein 33 83 6.5E-12 T 23-04-2016 IPR007341 Transglycosylase-associated protein GO:0016021 DC74_RS36625 082421e3c7be596638f3cbe7e673084c 88 PANTHER PTHR33884 2 88 2.6E-23 T 23-04-2016 DC74_RS03395 105ee77587e94233754cf0021397b0f4 300 SUPERFAMILY SSF53335 127 156 1.5E-5 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS03395 105ee77587e94233754cf0021397b0f4 300 SUPERFAMILY SSF53335 41 91 1.5E-5 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS09420 b79cbac19987ea77703643c674246260 107 SUPERFAMILY SSF46946 56 103 1.14E-7 T 23-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 DC74_RS09420 b79cbac19987ea77703643c674246260 107 Gene3D G3DSA:1.10.8.50 50 104 5.8E-14 T 23-04-2016 DC74_RS13040 4a5003fe200dbd79defba7711b48d87e 267 Pfam PF02654 Cobalamin-5-phosphate synthase 19 261 3.0E-42 T 23-04-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 DC74_RS13040 4a5003fe200dbd79defba7711b48d87e 267 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 267 39.476 T 23-04-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 DC74_RS13040 4a5003fe200dbd79defba7711b48d87e 267 PANTHER PTHR34148:SF1 6 267 1.7E-44 T 23-04-2016 DC74_RS13040 4a5003fe200dbd79defba7711b48d87e 267 PANTHER PTHR34148 6 267 1.7E-44 T 23-04-2016 DC74_RS14910 51d5e90a95b49bfbc786af178999bc2e 476 PANTHER PTHR11712 65 441 1.8E-42 T 23-04-2016 DC74_RS14910 51d5e90a95b49bfbc786af178999bc2e 476 SUPERFAMILY SSF48264 53 439 9.43E-58 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS14910 51d5e90a95b49bfbc786af178999bc2e 476 Gene3D G3DSA:1.10.630.10 47 440 2.0E-77 T 23-04-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 DC74_RS14910 51d5e90a95b49bfbc786af178999bc2e 476 PANTHER PTHR11712:SF282 65 441 1.8E-42 T 23-04-2016 DC74_RS14910 51d5e90a95b49bfbc786af178999bc2e 476 PRINTS PR00359 B-class P450 signature 182 198 3.0E-12 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14910 51d5e90a95b49bfbc786af178999bc2e 476 PRINTS PR00359 B-class P450 signature 136 147 3.0E-12 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14910 51d5e90a95b49bfbc786af178999bc2e 476 PRINTS PR00359 B-class P450 signature 331 358 3.0E-12 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS14910 51d5e90a95b49bfbc786af178999bc2e 476 PRINTS PR00359 B-class P450 signature 235 257 3.0E-12 T 23-04-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DC74_RS24660 ac821af10bfc59e029ccaacf62677947 409 Gene3D G3DSA:2.40.10.10 162 293 1.2E-7 T 23-04-2016 DC74_RS24660 ac821af10bfc59e029ccaacf62677947 409 SUPERFAMILY SSF50494 156 369 1.61E-14 T 23-04-2016 IPR009003 Peptidase S1, PA clan DC74_RS40715 fec48d11c7f77df1191044d3e3157fe0 231 PANTHER PTHR24095 24 149 6.9E-12 T 23-04-2016 DC74_RS40715 fec48d11c7f77df1191044d3e3157fe0 231 Pfam PF00501 AMP-binding enzyme 26 133 1.4E-16 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 DC74_RS40715 fec48d11c7f77df1191044d3e3157fe0 231 SUPERFAMILY SSF56801 18 172 4.58E-21 T 23-04-2016 DC74_RS40715 fec48d11c7f77df1191044d3e3157fe0 231 Gene3D G3DSA:3.40.50.980 21 149 1.3E-18 T 23-04-2016 DC74_RS30790 a35a4e6129a442cc68ebbb1b6687acf4 1005 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 742 977 2.6E-9 T 23-04-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain DC74_RS30790 a35a4e6129a442cc68ebbb1b6687acf4 1005 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 742 994 4.7E-40 T 23-04-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain DC74_RS30790 a35a4e6129a442cc68ebbb1b6687acf4 1005 Pfam PF04738 Lantibiotic dehydratase, C terminus 33 676 3.8E-190 T 23-04-2016 IPR006827 Lantibiotic dehydratase, C-terminal DC74_RS27240 c0aba186d69955182b3cdba311105412 216 Pfam PF16859 Bacterial transcriptional repressor C-terminal 84 204 2.7E-15 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS27240 c0aba186d69955182b3cdba311105412 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 72 9.2E-13 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS27240 c0aba186d69955182b3cdba311105412 216 PANTHER PTHR30055:SF74 12 213 1.6E-59 T 23-04-2016 DC74_RS27240 c0aba186d69955182b3cdba311105412 216 Gene3D G3DSA:1.10.10.60 18 65 2.2E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS27240 c0aba186d69955182b3cdba311105412 216 Gene3D G3DSA:1.10.357.10 67 211 6.0E-36 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS27240 c0aba186d69955182b3cdba311105412 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 3.5E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS27240 c0aba186d69955182b3cdba311105412 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 3.5E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS27240 c0aba186d69955182b3cdba311105412 216 SUPERFAMILY SSF46689 18 82 1.84E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS27240 c0aba186d69955182b3cdba311105412 216 PANTHER PTHR30055 12 213 1.6E-59 T 23-04-2016 DC74_RS27240 c0aba186d69955182b3cdba311105412 216 SUPERFAMILY SSF48498 88 211 1.11E-12 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS36550 6993799e6fac124d189a67f63f474d54 446 PANTHER PTHR30538:SF0 127 420 7.2E-111 T 23-04-2016 DC74_RS36550 6993799e6fac124d189a67f63f474d54 446 PANTHER PTHR30538:SF0 30 90 7.2E-111 T 23-04-2016 DC74_RS36550 6993799e6fac124d189a67f63f474d54 446 PANTHER PTHR30538 127 420 7.2E-111 T 23-04-2016 DC74_RS36550 6993799e6fac124d189a67f63f474d54 446 PANTHER PTHR30538 30 90 7.2E-111 T 23-04-2016 DC74_RS36550 6993799e6fac124d189a67f63f474d54 446 SUPERFAMILY SSF102114 149 355 2.75E-6 T 23-04-2016 DC74_RS38925 c8e01c6c2d5224383a9c742fd6b37abd 153 Pfam PF03779 SPW repeat 93 140 1.5E-12 T 23-04-2016 IPR005530 SPW repeat DC74_RS38925 c8e01c6c2d5224383a9c742fd6b37abd 153 Pfam PF03779 SPW repeat 38 83 4.7E-15 T 23-04-2016 IPR005530 SPW repeat DC74_RS01360 13947e020ab981ce3f09e6a9cdb37a9f 260 Pfam PF05988 Bacterial protein of unknown function (DUF899) 15 215 4.7E-58 T 23-04-2016 IPR010296 Protein of unknown function DUF899, thioredoxin-like DC74_RS25535 f199a2df059195061b1326ef4e119500 790 Pfam PF02687 FtsX-like permease family 672 781 5.2E-10 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS25535 f199a2df059195061b1326ef4e119500 790 Pfam PF02687 FtsX-like permease family 212 324 8.0E-7 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS15735 43ea9a70f28163b1adb36d473d1d5c2f 64 Gene3D G3DSA:1.10.1660.10 5 35 2.1E-4 T 23-04-2016 DC74_RS15735 43ea9a70f28163b1adb36d473d1d5c2f 64 SUPERFAMILY SSF46955 6 56 2.01E-6 T 23-04-2016 IPR009061 Putative DNA-binding domain DC74_RS37260 8428cf42be7f1f62ac87984ca5b81156 327 PANTHER PTHR10584 2 308 3.9E-105 T 23-04-2016 DC74_RS37260 8428cf42be7f1f62ac87984ca5b81156 327 Gene3D G3DSA:3.40.1190.20 2 308 2.1E-52 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS37260 8428cf42be7f1f62ac87984ca5b81156 327 SUPERFAMILY SSF53613 2 295 2.03E-56 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS37260 8428cf42be7f1f62ac87984ca5b81156 327 Pfam PF00294 pfkB family carbohydrate kinase 29 295 3.0E-43 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS37260 8428cf42be7f1f62ac87984ca5b81156 327 PANTHER PTHR10584:SF15 2 308 3.9E-105 T 23-04-2016 DC74_RS37260 8428cf42be7f1f62ac87984ca5b81156 327 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 251 264 - T 23-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 DC74_RS37260 8428cf42be7f1f62ac87984ca5b81156 327 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 23-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 DC74_RS39205 39ea49cb5801c937061d2d438d199d9a 199 SUPERFAMILY SSF53335 41 191 4.14E-17 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS39205 39ea49cb5801c937061d2d438d199d9a 199 Pfam PF13489 Methyltransferase domain 38 144 2.3E-10 T 23-04-2016 DC74_RS39205 39ea49cb5801c937061d2d438d199d9a 199 Gene3D G3DSA:3.40.50.150 42 145 3.3E-14 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS21645 501b2878d59a6fc27f5bf9569f046174 174 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 2 173 4.6E-25 T 23-04-2016 IPR023869 tRNA adenosine deaminase-associated protein, putative DC74_RS14970 622061912225d5d0c6d1ff1926b4963f 397 Pfam PF00294 pfkB family carbohydrate kinase 212 326 5.3E-20 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS14970 622061912225d5d0c6d1ff1926b4963f 397 Pfam PF00294 pfkB family carbohydrate kinase 63 145 2.7E-7 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB DC74_RS14970 622061912225d5d0c6d1ff1926b4963f 397 Gene3D G3DSA:3.40.1190.20 35 338 1.7E-54 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS14970 622061912225d5d0c6d1ff1926b4963f 397 PANTHER PTHR10584 18 359 1.1E-92 T 23-04-2016 DC74_RS14970 622061912225d5d0c6d1ff1926b4963f 397 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 279 292 - T 23-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 DC74_RS14970 622061912225d5d0c6d1ff1926b4963f 397 PANTHER PTHR10584:SF157 18 359 1.1E-92 T 23-04-2016 DC74_RS14970 622061912225d5d0c6d1ff1926b4963f 397 SUPERFAMILY SSF53613 35 335 2.14E-49 T 23-04-2016 IPR029056 Ribokinase-like DC74_RS11260 c46a457c352235f11b21adbbd500b8e1 70 Pfam PF03777 Small secreted domain (DUF320) 14 69 2.0E-28 T 23-04-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species DC74_RS40445 4d952bede6ee166038a31d9ad16d9e58 172 SUPERFAMILY SSF50370 75 168 2.96E-7 T 23-04-2016 IPR000772 Ricin B, lectin domain DC74_RS40445 4d952bede6ee166038a31d9ad16d9e58 172 Gene3D G3DSA:2.80.10.50 77 169 1.1E-6 T 23-04-2016 DC74_RS15460 44675f3f176a428bee97679cf91c8af0 730 PANTHER PTHR32438 566 729 5.0E-173 T 23-04-2016 DC74_RS15460 44675f3f176a428bee97679cf91c8af0 730 PANTHER PTHR32438 153 533 5.0E-173 T 23-04-2016 DC74_RS15460 44675f3f176a428bee97679cf91c8af0 730 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 118 537 1.3E-79 T 23-04-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 DC74_RS15460 44675f3f176a428bee97679cf91c8af0 730 SUPERFAMILY SSF51445 648 725 1.94E-128 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS15460 44675f3f176a428bee97679cf91c8af0 730 SUPERFAMILY SSF51445 575 605 1.94E-128 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS15460 44675f3f176a428bee97679cf91c8af0 730 SUPERFAMILY SSF51445 148 538 1.94E-128 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS15460 44675f3f176a428bee97679cf91c8af0 730 Pfam PF02446 4-alpha-glucanotransferase 159 535 5.3E-97 T 23-04-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 DC74_RS15460 44675f3f176a428bee97679cf91c8af0 730 Pfam PF02446 4-alpha-glucanotransferase 576 698 1.0E-11 T 23-04-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 DC74_RS15460 44675f3f176a428bee97679cf91c8af0 730 Gene3D G3DSA:3.20.20.80 575 703 1.1E-159 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS15460 44675f3f176a428bee97679cf91c8af0 730 Gene3D G3DSA:3.20.20.80 152 538 1.1E-159 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 DC74_RS15460 44675f3f176a428bee97679cf91c8af0 730 PANTHER PTHR32438:SF5 566 729 5.0E-173 T 23-04-2016 DC74_RS15460 44675f3f176a428bee97679cf91c8af0 730 PANTHER PTHR32438:SF5 153 533 5.0E-173 T 23-04-2016 DC74_RS33810 aa1e7f70e37505c00de1d2ced7867bee 150 PANTHER PTHR31793 10 150 6.1E-31 T 23-04-2016 DC74_RS33810 aa1e7f70e37505c00de1d2ced7867bee 150 Pfam PF13279 Thioesterase-like superfamily 21 126 1.1E-18 T 23-04-2016 DC74_RS33810 aa1e7f70e37505c00de1d2ced7867bee 150 SUPERFAMILY SSF54637 10 137 9.47E-38 T 23-04-2016 IPR029069 HotDog domain DC74_RS33810 aa1e7f70e37505c00de1d2ced7867bee 150 Gene3D G3DSA:3.10.129.10 9 133 1.8E-36 T 23-04-2016 IPR029069 HotDog domain DC74_RS32255 15ad1a324e1cc51c94e491ad4aca0b0d 135 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 13 133 8.2E-21 T 23-04-2016 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 DC74_RS32255 15ad1a324e1cc51c94e491ad4aca0b0d 135 Gene3D G3DSA:3.10.450.50 8 133 9.6E-28 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS32255 15ad1a324e1cc51c94e491ad4aca0b0d 135 Pfam PF14534 Domain of unknown function (DUF4440) 18 125 1.5E-11 T 23-04-2016 IPR027843 Domain of unknown function DUF4440 DC74_RS32255 15ad1a324e1cc51c94e491ad4aca0b0d 135 SUPERFAMILY SSF54427 13 133 1.82E-26 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS25125 9a59135a6043c7c569d37e97d06ff8f1 71 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 2 64 4.5E-17 T 23-04-2016 IPR032716 Acyl-CoA carboxylase epsilon subunit DC74_RS06890 5623ca0fea08b2a3ad88c094e8924146 336 PANTHER PTHR30590:SF3 13 336 2.7E-37 T 23-04-2016 DC74_RS06890 5623ca0fea08b2a3ad88c094e8924146 336 Pfam PF04235 Protein of unknown function (DUF418) 194 329 9.4E-28 T 23-04-2016 IPR007349 Domain of unknown function DUF418 DC74_RS06890 5623ca0fea08b2a3ad88c094e8924146 336 PANTHER PTHR30590 13 336 2.7E-37 T 23-04-2016 DC74_RS00470 1d27ceb3e6c21234c23dd7891b2f4be9 99 Gene3D G3DSA:1.10.10.10 3 87 9.6E-28 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00470 1d27ceb3e6c21234c23dd7891b2f4be9 99 PANTHER PTHR33154 2 85 1.9E-16 T 23-04-2016 DC74_RS00470 1d27ceb3e6c21234c23dd7891b2f4be9 99 SMART SM00418 4 85 4.5E-16 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS00470 1d27ceb3e6c21234c23dd7891b2f4be9 99 SUPERFAMILY SSF46785 4 86 7.98E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00470 1d27ceb3e6c21234c23dd7891b2f4be9 99 Pfam PF12840 Helix-turn-helix domain 4 69 5.6E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS00470 1d27ceb3e6c21234c23dd7891b2f4be9 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 6 21 8.6E-7 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS00470 1d27ceb3e6c21234c23dd7891b2f4be9 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 8.6E-7 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DC74_RS08985 920cdf55d9d742c24f5dd586fae66557 201 Pfam PF17197 Domain of unknown function (DUF5134) 33 201 1.7E-33 T 23-04-2016 IPR033458 Protein of unknown function DUF5134 DC74_RS19825 3a0782505373152eeda76f2198f4a408 186 Gene3D G3DSA:1.10.10.10 22 97 5.7E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19825 3a0782505373152eeda76f2198f4a408 186 SUPERFAMILY SSF46785 22 126 1.73E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS19825 3a0782505373152eeda76f2198f4a408 186 Pfam PF12802 MarR family 35 94 1.7E-8 T 23-04-2016 DC74_RS33105 2c83c15955e0e1d1ec4178515c0d8c53 450 Gene3D G3DSA:3.40.630.10 59 342 7.9E-33 T 23-04-2016 DC74_RS33105 2c83c15955e0e1d1ec4178515c0d8c53 450 SUPERFAMILY SSF53187 51 301 4.96E-40 T 23-04-2016 DC74_RS33105 2c83c15955e0e1d1ec4178515c0d8c53 450 Pfam PF00246 Zinc carboxypeptidase 72 189 2.2E-20 T 23-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 DC74_RS33105 2c83c15955e0e1d1ec4178515c0d8c53 450 SMART SM00631 51 280 3.4E-5 T 23-04-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 DC74_RS24120 678318ffbbe2afdcb1c14853189cf9f8 288 Pfam PF04542 Sigma-70 region 2 25 92 8.0E-11 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS24120 678318ffbbe2afdcb1c14853189cf9f8 288 SUPERFAMILY SSF88659 183 274 1.03E-6 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS24120 678318ffbbe2afdcb1c14853189cf9f8 288 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 270 1.9E-18 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS24120 678318ffbbe2afdcb1c14853189cf9f8 288 Gene3D G3DSA:1.10.10.10 243 273 8.1E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS24120 678318ffbbe2afdcb1c14853189cf9f8 288 SUPERFAMILY SSF88946 6 92 6.15E-17 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 DC74_RS24120 678318ffbbe2afdcb1c14853189cf9f8 288 Gene3D G3DSA:1.10.601.10 6 92 1.5E-11 T 23-04-2016 DC74_RS11080 7dff1d1b66cdb91cf890f404948711d1 395 PANTHER PTHR38165 1 395 3.5E-146 T 23-04-2016 DC74_RS11080 7dff1d1b66cdb91cf890f404948711d1 395 PANTHER PTHR38165:SF2 1 395 3.5E-146 T 23-04-2016 DC74_RS11080 7dff1d1b66cdb91cf890f404948711d1 395 Pfam PF16483 Beta-1,3-glucanase 35 392 6.0E-97 T 23-04-2016 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 DC74_RS23175 a572f0c6c730343cf62cc294b788e8e6 233 Pfam PF11209 Protein of unknown function (DUF2993) 20 225 3.2E-26 T 23-04-2016 IPR021373 Protein of unknown function DUF2993 DC74_RS03995 9e244683129d7932acd681f322b85bbc 152 Gene3D G3DSA:3.10.129.10 7 144 4.8E-40 T 23-04-2016 IPR029069 HotDog domain DC74_RS03995 9e244683129d7932acd681f322b85bbc 152 Pfam PF03061 Thioesterase superfamily 46 102 1.0E-7 T 23-04-2016 IPR006683 Thioesterase domain DC74_RS03995 9e244683129d7932acd681f322b85bbc 152 SUPERFAMILY SSF54637 11 145 3.97E-35 T 23-04-2016 IPR029069 HotDog domain DC74_RS03995 9e244683129d7932acd681f322b85bbc 152 PANTHER PTHR31793 13 145 1.3E-20 T 23-04-2016 DC74_RS26975 b003b05b6735d3d67eab0c52a392374c 377 SUPERFAMILY SSF52402 229 253 3.49E-12 T 23-04-2016 DC74_RS26975 b003b05b6735d3d67eab0c52a392374c 377 SUPERFAMILY SSF52402 57 196 3.49E-12 T 23-04-2016 DC74_RS26975 b003b05b6735d3d67eab0c52a392374c 377 Gene3D G3DSA:3.40.50.620 63 175 4.2E-8 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DC74_RS25200 680daac9dc037a6d59c2c924b5217e81 546 SUPERFAMILY SSF53474 386 477 9.34E-5 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS25200 680daac9dc037a6d59c2c924b5217e81 546 Pfam PF06259 Alpha/beta hydrolase 299 477 1.5E-35 T 23-04-2016 IPR010427 Protein of unknown function DUF1023 DC74_RS24500 affdfa089f7e3d662b96078ab430e641 326 Pfam PF14065 Protein of unknown function (DUF4255) 9 192 1.4E-42 T 23-04-2016 IPR025351 Protein of unknown function DUF4255 DC74_RS33535 811564ff9283d8f0212be08850d4cf73 478 ProSitePatterns PS00218 Amino acid permeases signature. 68 98 - T 23-04-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 DC74_RS33535 811564ff9283d8f0212be08850d4cf73 478 PANTHER PTHR11785 7 477 2.8E-182 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS33535 811564ff9283d8f0212be08850d4cf73 478 PANTHER PTHR11785:SF24 7 477 2.8E-182 T 23-04-2016 DC74_RS33535 811564ff9283d8f0212be08850d4cf73 478 PIRSF PIRSF006060 13 475 3.9E-62 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 DC74_RS33535 811564ff9283d8f0212be08850d4cf73 478 Pfam PF00324 Amino acid permease 43 477 1.8E-97 T 23-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 DC74_RS38470 c0c320f1b8f10d46b749d8055cf466e3 285 SUPERFAMILY SSF161098 78 265 8.5E-26 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38470 c0c320f1b8f10d46b749d8055cf466e3 285 PANTHER PTHR30465 1 285 1.4E-73 T 23-04-2016 DC74_RS38470 c0c320f1b8f10d46b749d8055cf466e3 285 PANTHER PTHR30465:SF10 1 285 1.4E-73 T 23-04-2016 DC74_RS38470 c0c320f1b8f10d46b749d8055cf466e3 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 283 3.4E-29 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS38470 c0c320f1b8f10d46b749d8055cf466e3 285 Gene3D G3DSA:1.10.3720.10 74 281 8.8E-25 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS37385 30877299543672a7fdebc24734d475ee 192 PANTHER PTHR42305 7 192 1.5E-31 T 23-04-2016 DC74_RS29275 ae04036d208370e815c5f2da71dd973b 350 Gene3D G3DSA:3.40.47.10 205 346 5.6E-34 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29275 ae04036d208370e815c5f2da71dd973b 350 PIRSF PIRSF000451 1 349 2.7E-110 T 23-04-2016 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 DC74_RS29275 ae04036d208370e815c5f2da71dd973b 350 PANTHER PTHR11877 10 347 4.5E-74 T 23-04-2016 DC74_RS29275 ae04036d208370e815c5f2da71dd973b 350 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 210 341 1.2E-18 T 23-04-2016 IPR012328 Chalcone/stilbene synthase, C-terminal DC74_RS29275 ae04036d208370e815c5f2da71dd973b 350 Gene3D G3DSA:3.40.47.10 1 199 3.8E-53 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29275 ae04036d208370e815c5f2da71dd973b 350 SUPERFAMILY SSF53901 204 346 2.59E-36 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29275 ae04036d208370e815c5f2da71dd973b 350 SUPERFAMILY SSF53901 2 202 5.38E-46 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 DC74_RS29275 ae04036d208370e815c5f2da71dd973b 350 Pfam PF08392 FAE1/Type III polyketide synthase-like protein 25 197 3.8E-16 T 23-04-2016 IPR013601 FAE1/Type III polyketide synthase-like protein GO:0006633|GO:0016020|GO:0016747 KEGG: 00062+2.3.1.199|KEGG: 00650+2.3.1.19|MetaCyc: PWY-5080|MetaCyc: PWY-5972|MetaCyc: PWY-6433|MetaCyc: PWY-6598|MetaCyc: PWY-7036|MetaCyc: PWY-7601|MetaCyc: PWY-7602|MetaCyc: PWY-7619|MetaCyc: PWY-7724|MetaCyc: PWY-7725|UniPathway: UPA00094 DC74_RS29275 ae04036d208370e815c5f2da71dd973b 350 PANTHER PTHR11877:SF10 10 347 4.5E-74 T 23-04-2016 DC74_RS21115 a4c39308d7e8f7edab16c2258c5a022d 430 PANTHER PTHR23523:SF2 14 430 4.8E-144 T 23-04-2016 DC74_RS21115 a4c39308d7e8f7edab16c2258c5a022d 430 PANTHER PTHR23523 14 430 4.8E-144 T 23-04-2016 DC74_RS21115 a4c39308d7e8f7edab16c2258c5a022d 430 Pfam PF07690 Major Facilitator Superfamily 46 384 7.4E-21 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS21115 a4c39308d7e8f7edab16c2258c5a022d 430 SUPERFAMILY SSF103473 26 422 2.62E-42 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS21115 a4c39308d7e8f7edab16c2258c5a022d 430 Gene3D G3DSA:1.20.1250.20 30 216 2.4E-12 T 23-04-2016 DC74_RS21115 a4c39308d7e8f7edab16c2258c5a022d 430 Gene3D G3DSA:1.20.1250.20 239 418 3.8E-17 T 23-04-2016 DC74_RS03655 0a5fb06473c03246d93088b71d16fa79 448 Pfam PF10011 Predicted membrane protein (DUF2254) 19 387 2.6E-75 T 23-04-2016 IPR018723 Protein of unknown function DUF2254, membrane DC74_RS27210 bbdd779815ae88085bfb9aa5d962f180 110 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 92 3.0E-26 T 23-04-2016 IPR023845 Domain of unknown function DUF3817, transmembrane DC74_RS27210 bbdd779815ae88085bfb9aa5d962f180 110 PANTHER PTHR40077 1 110 1.6E-23 T 23-04-2016 DC74_RS27210 bbdd779815ae88085bfb9aa5d962f180 110 Pfam PF12823 Domain of unknown function (DUF3817) 6 94 1.0E-26 T 23-04-2016 IPR023845 Domain of unknown function DUF3817, transmembrane DC74_RS04040 b48d8fc318b3b1105a4530fec8e3d7e4 170 Pfam PF13546 DDE superfamily endonuclease 26 152 3.4E-20 T 23-04-2016 DC74_RS06440 7a3f206d5f2c433cfcc76b0cf3557e71 154 Gene3D G3DSA:3.30.530.20 5 151 6.4E-28 T 23-04-2016 IPR023393 START-like domain DC74_RS06440 7a3f206d5f2c433cfcc76b0cf3557e71 154 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 12 151 6.1E-20 T 23-04-2016 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 DC74_RS06440 7a3f206d5f2c433cfcc76b0cf3557e71 154 SUPERFAMILY SSF55961 4 151 4.69E-31 T 23-04-2016 DC74_RS10545 07d5847352daeece16a8665ff22983fe 135 Gene3D G3DSA:3.40.30.10 16 96 5.8E-5 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS38660 345e25ed2e6b97ce8a76a08f6d96943e 1070 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 789 1057 2.1E-45 T 23-04-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain DC74_RS38660 345e25ed2e6b97ce8a76a08f6d96943e 1070 Pfam PF04738 Lantibiotic dehydratase, C terminus 51 712 2.3E-173 T 23-04-2016 IPR006827 Lantibiotic dehydratase, C-terminal DC74_RS38660 345e25ed2e6b97ce8a76a08f6d96943e 1070 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 789 1056 4.1E-27 T 23-04-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain DC74_RS32800 4e3241f5910de09acb60bb927c79cb0e 358 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 48 329 9.5E-123 T 23-04-2016 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 DC74_RS32800 4e3241f5910de09acb60bb927c79cb0e 358 Pfam PF03824 High-affinity nickel-transport protein 46 333 6.0E-92 T 23-04-2016 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 DC74_RS32800 4e3241f5910de09acb60bb927c79cb0e 358 PANTHER PTHR31611 1 346 2.8E-99 T 23-04-2016 DC74_RS36555 2213667e513c4200a99e70c8bd45e38d 423 PANTHER PTHR11751 9 378 7.4E-52 T 23-04-2016 DC74_RS36555 2213667e513c4200a99e70c8bd45e38d 423 Pfam PF00155 Aminotransferase class I and II 48 380 2.2E-37 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS36555 2213667e513c4200a99e70c8bd45e38d 423 Gene3D G3DSA:3.40.640.10 49 236 5.0E-42 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS36555 2213667e513c4200a99e70c8bd45e38d 423 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 23-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 DC74_RS36555 2213667e513c4200a99e70c8bd45e38d 423 SUPERFAMILY SSF53383 9 381 1.24E-59 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS36555 2213667e513c4200a99e70c8bd45e38d 423 Gene3D G3DSA:3.90.1150.10 237 382 2.6E-14 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS39540 67ff994baf4c6bab8175030874bae65c 388 Pfam PF07730 Histidine kinase 194 262 1.1E-11 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 DC74_RS39540 67ff994baf4c6bab8175030874bae65c 388 Gene3D G3DSA:3.30.565.10 296 385 5.5E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS39540 67ff994baf4c6bab8175030874bae65c 388 PANTHER PTHR24421:SF19 172 383 4.7E-52 T 23-04-2016 DC74_RS39540 67ff994baf4c6bab8175030874bae65c 388 SUPERFAMILY SSF55874 268 380 9.99E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS39540 67ff994baf4c6bab8175030874bae65c 388 PANTHER PTHR24421 172 383 4.7E-52 T 23-04-2016 DC74_RS32685 e00732f39ebb423bbeec3dcac7002513 443 PANTHER PTHR32468 13 414 1.2E-67 T 23-04-2016 DC74_RS32685 e00732f39ebb423bbeec3dcac7002513 443 Pfam PF00999 Sodium/hydrogen exchanger family 14 415 1.4E-42 T 23-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 DC74_RS00195 56f0277284bafa3863d0b482d5414e85 518 TIGRFAM TIGR02677 TIGR02677: TIGR02677 family protein 7 501 8.3E-182 T 23-04-2016 IPR013493 Conserved hypothetical protein CHP02677 DC74_RS00195 56f0277284bafa3863d0b482d5414e85 518 Pfam PF09660 Protein of unknown function (DUF2397) 9 493 1.2E-139 T 23-04-2016 IPR013493 Conserved hypothetical protein CHP02677 DC74_RS06035 278773f7137daf17fd8cbe321f726d60 176 SUPERFAMILY SSF55729 4 160 6.48E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06035 278773f7137daf17fd8cbe321f726d60 176 Pfam PF00583 Acetyltransferase (GNAT) family 69 156 8.5E-6 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS06035 278773f7137daf17fd8cbe321f726d60 176 Gene3D G3DSA:3.40.630.30 4 157 6.3E-23 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS31295 18403fa206c640a941fcfc68308a7d89 125 PANTHER PTHR35145 5 121 1.8E-40 T 23-04-2016 DC74_RS31295 18403fa206c640a941fcfc68308a7d89 125 SUPERFAMILY SSF142906 3 118 5.36E-37 T 23-04-2016 DC74_RS31295 18403fa206c640a941fcfc68308a7d89 125 Pfam PF04237 YjbR 12 105 1.1E-28 T 23-04-2016 IPR007351 Uncharacterised protein YjbR DC74_RS35630 eb6c2e1ca5ca1f08adb9aeab8dbb706f 273 Hamap MF_01384 Urease accessory protein UreD [ureD]. 11 265 18.515 T 23-04-2016 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 DC74_RS35630 eb6c2e1ca5ca1f08adb9aeab8dbb706f 273 Pfam PF01774 UreD urease accessory protein 64 221 3.7E-27 T 23-04-2016 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 DC74_RS15045 4c1c5433a9bca23251856b8b563baa2e 283 Pfam PF11296 Protein of unknown function (DUF3097) 14 273 4.6E-125 T 23-04-2016 IPR021447 Protein of unknown function DUF3097 DC74_RS29175 c6879761d8d229572c0b17fdde2be86f 252 Pfam PF12502 Protein of unknown function (DUF3710) 46 219 9.3E-62 T 23-04-2016 IPR022183 Protein of unknown function DUF3710 DC74_RS03755 adc12e0088c3f726702273fc2bf5b31b 327 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 136 321 2.0E-6 T 23-04-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain DC74_RS03755 adc12e0088c3f726702273fc2bf5b31b 327 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 73 317 1.6E-16 T 23-04-2016 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain DC74_RS14700 3925062b96e0e9cf036fb5106d71a1f9 95 Pfam PF04149 Domain of unknown function (DUF397) 33 89 2.0E-18 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS14700 3925062b96e0e9cf036fb5106d71a1f9 95 Pfam PF04149 Domain of unknown function (DUF397) 10 28 1.3E-5 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS11750 916e8e6bfb5c5280e91c6c910a5534af 262 PIRSF PIRSF006648 7 262 1.1E-33 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 DC74_RS11750 916e8e6bfb5c5280e91c6c910a5534af 262 Pfam PF01061 ABC-2 type transporter 28 229 1.3E-20 T 23-04-2016 IPR013525 ABC-2 type transporter GO:0016020 DC74_RS00025 77a8e9f0a52699fbc41f3b20f22f640c 102 Gene3D G3DSA:3.10.180.10 3 66 4.7E-6 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS00025 77a8e9f0a52699fbc41f3b20f22f640c 102 SUPERFAMILY SSF54593 3 98 2.13E-8 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS30820 49ca814f1d90d88fc31f47fed0a85e78 256 PANTHER PTHR33542 1 255 3.9E-55 T 23-04-2016 DC74_RS30820 49ca814f1d90d88fc31f47fed0a85e78 256 Gene3D G3DSA:3.40.50.1400 131 244 5.7E-20 T 23-04-2016 DC74_RS30820 49ca814f1d90d88fc31f47fed0a85e78 256 Gene3D G3DSA:3.40.50.1400 6 125 1.5E-26 T 23-04-2016 DC74_RS30820 49ca814f1d90d88fc31f47fed0a85e78 256 Pfam PF01903 CbiX 140 235 1.6E-12 T 23-04-2016 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377|UniPathway: UPA00148 DC74_RS30820 49ca814f1d90d88fc31f47fed0a85e78 256 Pfam PF01903 CbiX 12 116 3.9E-23 T 23-04-2016 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377|UniPathway: UPA00148 DC74_RS30820 49ca814f1d90d88fc31f47fed0a85e78 256 SUPERFAMILY SSF53800 6 243 2.07E-41 T 23-04-2016 DC74_RS08295 4a4a9af7e11288efd9d95be5765f3da3 270 Pfam PF03746 LamB/YcsF family 22 259 1.0E-99 T 23-04-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF DC74_RS08295 4a4a9af7e11288efd9d95be5765f3da3 270 PANTHER PTHR30292 18 270 2.1E-121 T 23-04-2016 DC74_RS08295 4a4a9af7e11288efd9d95be5765f3da3 270 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 20 264 43.758 T 23-04-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF DC74_RS08295 4a4a9af7e11288efd9d95be5765f3da3 270 SUPERFAMILY SSF88713 22 269 1.93E-94 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS08295 4a4a9af7e11288efd9d95be5765f3da3 270 PANTHER PTHR30292:SF0 18 270 2.1E-121 T 23-04-2016 DC74_RS15635 0d43b896e646bd28a4762c97fc74b39a 218 PANTHER PTHR30574 117 215 1.4E-16 T 23-04-2016 DC74_RS15635 0d43b896e646bd28a4762c97fc74b39a 218 Pfam PF04143 Sulphur transport 5 207 6.8E-14 T 23-04-2016 IPR007272 Sulphur transport domain DC74_RS15635 0d43b896e646bd28a4762c97fc74b39a 218 PANTHER PTHR30574:SF1 117 215 1.4E-16 T 23-04-2016 DC74_RS39850 425a42d9287e9ec7b08d783ccbca4ded 326 SUPERFAMILY SSF55961 153 306 1.07E-5 T 23-04-2016 DC74_RS32170 7be1e25707d62d2f873b2f79417a118c 178 Pfam PF09335 SNARE associated Golgi protein 8 133 1.5E-8 T 23-04-2016 IPR032816 SNARE associated Golgi protein DC74_RS29125 2a1cb039d2ae33d0ef0819f79308e8bd 427 Pfam PF07690 Major Facilitator Superfamily 29 270 5.7E-11 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DC74_RS29125 2a1cb039d2ae33d0ef0819f79308e8bd 427 SUPERFAMILY SSF103473 17 397 2.09E-31 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS29125 2a1cb039d2ae33d0ef0819f79308e8bd 427 PANTHER PTHR23542:SF1 2 425 2.1E-135 T 23-04-2016 DC74_RS29125 2a1cb039d2ae33d0ef0819f79308e8bd 427 PANTHER PTHR23542 2 425 2.1E-135 T 23-04-2016 DC74_RS29125 2a1cb039d2ae33d0ef0819f79308e8bd 427 Gene3D G3DSA:1.20.1250.20 18 192 2.9E-9 T 23-04-2016 DC74_RS29125 2a1cb039d2ae33d0ef0819f79308e8bd 427 Gene3D G3DSA:1.20.1250.20 213 397 3.0E-14 T 23-04-2016 DC74_RS40575 238c157673e4685b2109553f4fa534e0 155 Pfam PF00293 NUDIX domain 4 78 7.7E-17 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 DC74_RS40575 238c157673e4685b2109553f4fa534e0 155 SUPERFAMILY SSF55811 5 80 4.74E-22 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS40575 238c157673e4685b2109553f4fa534e0 155 PANTHER PTHR22769 4 72 3.2E-13 T 23-04-2016 DC74_RS40575 238c157673e4685b2109553f4fa534e0 155 Gene3D G3DSA:3.90.79.10 4 108 7.0E-23 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 DC74_RS40575 238c157673e4685b2109553f4fa534e0 155 PRINTS PR00502 NUDIX hydrolase family signature 31 45 2.6E-7 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS40575 238c157673e4685b2109553f4fa534e0 155 PRINTS PR00502 NUDIX hydrolase family signature 45 60 2.6E-7 T 23-04-2016 IPR020476 NUDIX hydrolase DC74_RS39230 c422bb321064825f4ca0868e2ea70fd4 404 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 177 276 2.3E-13 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS39230 c422bb321064825f4ca0868e2ea70fd4 404 Gene3D G3DSA:3.40.50.1110 160 379 1.2E-13 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS39230 c422bb321064825f4ca0868e2ea70fd4 404 SUPERFAMILY SSF52266 171 380 8.74E-28 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain DC74_RS24635 2c46106ed25c55d36b889222ca9cacff 216 SUPERFAMILY SSF52317 19 191 1.25E-13 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS24635 2c46106ed25c55d36b889222ca9cacff 216 Gene3D G3DSA:3.40.50.880 15 192 1.1E-17 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like DC74_RS24635 2c46106ed25c55d36b889222ca9cacff 216 Pfam PF09825 Biotin-protein ligase, N terminal 56 100 7.2E-7 T 23-04-2016 IPR019197 Biotin-protein ligase, N-terminal DC74_RS23475 ab36b5a9afdb31b8f8b58a330e805442 298 Gene3D G3DSA:2.60.120.260 185 295 1.2E-12 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS23475 ab36b5a9afdb31b8f8b58a330e805442 298 SUPERFAMILY SSF49785 186 295 1.23E-10 T 23-04-2016 IPR008979 Galactose-binding domain-like DC74_RS04950 daf8f5330d4a51236b59f041d2ac9ce4 177 Pfam PF07681 DoxX 4 87 8.9E-12 T 23-04-2016 IPR032808 DoxX family DC74_RS04950 daf8f5330d4a51236b59f041d2ac9ce4 177 PANTHER PTHR33452 1 130 1.4E-27 T 23-04-2016 DC74_RS04950 daf8f5330d4a51236b59f041d2ac9ce4 177 PANTHER PTHR33452:SF1 1 130 1.4E-27 T 23-04-2016 DC74_RS07155 328ceb0afd4e77d509fb2e5fdb3b4306 268 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 36 59 4.1E-6 T 23-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 DC74_RS07155 328ceb0afd4e77d509fb2e5fdb3b4306 268 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 78 98 4.1E-6 T 23-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 DC74_RS07155 328ceb0afd4e77d509fb2e5fdb3b4306 268 Pfam PF13437 HlyD family secretion protein 107 196 1.5E-6 T 23-04-2016 DC74_RS07155 328ceb0afd4e77d509fb2e5fdb3b4306 268 Gene3D G3DSA:2.40.50.100 66 137 2.7E-11 T 23-04-2016 DC74_RS07155 328ceb0afd4e77d509fb2e5fdb3b4306 268 SUPERFAMILY SSF51230 63 137 6.71E-9 T 23-04-2016 IPR011053 Single hybrid motif DC74_RS02020 5d4828f67ada42d3ec3ccecbdec6c60d 372 Pfam PF13480 Acetyltransferase (GNAT) domain 187 320 3.2E-14 T 23-04-2016 DC74_RS02020 5d4828f67ada42d3ec3ccecbdec6c60d 372 SUPERFAMILY SSF55729 178 317 7.42E-14 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS07160 92d9b5cc3acf7c785855f763dc59c099 71 Pfam PF04604 Type-A lantibiotic 3 33 1.4E-5 T 23-04-2016 IPR007682 Lantibiotic, type A, Lactobacillales-type GO:0005576|GO:0042742 DC74_RS09365 8c4eb16467a14aae69fe93039d33ac25 244 SUPERFAMILY SSF140453 22 101 7.72E-6 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS09365 8c4eb16467a14aae69fe93039d33ac25 244 Pfam PF06013 Proteins of 100 residues with WXG 23 100 7.9E-7 T 23-04-2016 IPR010310 Type VII secretion system ESAT-6-like DC74_RS09365 8c4eb16467a14aae69fe93039d33ac25 244 Gene3D G3DSA:1.10.287.1060 22 102 2.4E-4 T 23-04-2016 DC74_RS36850 4b2a870851b24b6e85b39bd703e7fd3e 157 SUPERFAMILY SSF55729 7 151 2.84E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS36850 4b2a870851b24b6e85b39bd703e7fd3e 157 PANTHER PTHR23091 8 135 7.2E-20 T 23-04-2016 DC74_RS36850 4b2a870851b24b6e85b39bd703e7fd3e 157 Gene3D G3DSA:3.40.630.30 6 154 2.2E-28 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS36850 4b2a870851b24b6e85b39bd703e7fd3e 157 Pfam PF13673 Acetyltransferase (GNAT) domain 42 139 1.2E-14 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS14195 6c6e0736c13adc7eeca2034b25276d9c 204 PANTHER PTHR23029 1 200 3.6E-71 T 23-04-2016 DC74_RS14195 6c6e0736c13adc7eeca2034b25276d9c 204 SUPERFAMILY SSF53254 3 202 1.96E-46 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS14195 6c6e0736c13adc7eeca2034b25276d9c 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 201 1.4E-48 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS14195 6c6e0736c13adc7eeca2034b25276d9c 204 Gene3D G3DSA:3.40.50.1240 3 201 4.9E-44 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS14195 6c6e0736c13adc7eeca2034b25276d9c 204 SMART SM00855 3 162 4.9E-22 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 DC74_RS14195 6c6e0736c13adc7eeca2034b25276d9c 204 PANTHER PTHR23029:SF54 1 200 3.6E-71 T 23-04-2016 DC74_RS07275 fef9c7731f81770a5feffd42a33a671c 413 SUPERFAMILY SSF56801 179 324 4.73E-6 T 23-04-2016 DC74_RS18820 3d1ee4ad26462e366388ee05bea76dc7 411 PANTHER PTHR11751 26 409 5.2E-151 T 23-04-2016 DC74_RS18820 3d1ee4ad26462e366388ee05bea76dc7 411 PANTHER PTHR11751:SF306 26 409 5.2E-151 T 23-04-2016 DC74_RS18820 3d1ee4ad26462e366388ee05bea76dc7 411 Gene3D G3DSA:3.40.640.10 56 286 6.0E-77 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 DC74_RS18820 3d1ee4ad26462e366388ee05bea76dc7 411 SUPERFAMILY SSF53383 19 409 1.34E-111 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase DC74_RS18820 3d1ee4ad26462e366388ee05bea76dc7 411 Gene3D G3DSA:3.90.1150.10 287 409 5.4E-36 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS18820 3d1ee4ad26462e366388ee05bea76dc7 411 Pfam PF00155 Aminotransferase class I and II 44 400 4.6E-74 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DC74_RS18820 3d1ee4ad26462e366388ee05bea76dc7 411 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 248 261 - T 23-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 DC74_RS12970 3fc8022310f647becf7c447134344529 65 Pfam PF04149 Domain of unknown function (DUF397) 10 64 5.4E-24 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS02960 5faf5463ec6370c8dd76c74aa5f24a8f 148 SUPERFAMILY SSF54427 2 121 2.86E-15 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS02960 5faf5463ec6370c8dd76c74aa5f24a8f 148 Pfam PF12680 SnoaL-like domain 6 106 5.6E-10 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS02960 5faf5463ec6370c8dd76c74aa5f24a8f 148 Gene3D G3DSA:3.10.450.50 5 125 6.3E-13 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS30115 7b29707a5057868312d4b5ea4d554103 290 Pfam PF05107 CRISPR-associated protein Cas7 11 274 5.6E-87 T 23-04-2016 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C DC74_RS30115 7b29707a5057868312d4b5ea4d554103 290 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 10 274 8.0E-67 T 23-04-2016 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C DC74_RS30115 7b29707a5057868312d4b5ea4d554103 290 TIGRFAM TIGR02589 cas_Csd2: CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG 11 287 1.9E-83 T 23-04-2016 IPR013418 CRISPR-associated protein Csd2 DC74_RS33260 ef8536ba9e10c860c66f2532a5ba09c7 127 Pfam PF13581 Histidine kinase-like ATPase domain 2 113 7.2E-18 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33260 ef8536ba9e10c860c66f2532a5ba09c7 127 SUPERFAMILY SSF55874 25 122 1.7E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS33260 ef8536ba9e10c860c66f2532a5ba09c7 127 Gene3D G3DSA:3.30.565.10 8 98 4.1E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS35595 d513b0c197f04c437657e6890851016a 104 Gene3D G3DSA:3.40.1620.10 3 51 7.3E-15 T 23-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM DC74_RS35595 d513b0c197f04c437657e6890851016a 104 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 55 4.2E-18 T 23-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM DC74_RS35595 d513b0c197f04c437657e6890851016a 104 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 62 4.8E-15 T 23-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM DC74_RS35595 d513b0c197f04c437657e6890851016a 104 SUPERFAMILY SSF143120 5 67 4.62E-13 T 23-04-2016 DC74_RS27485 28232bfd2c2047218b8ac8f87c6a6f21 246 Pfam PF14581 SseB protein C-terminal domain 121 225 1.3E-16 T 23-04-2016 IPR027945 SseB protein, C-terminal DC74_RS08280 c573e73c6f9fc7221ca3510ef73bad91 322 Pfam PF06166 Protein of unknown function (DUF979) 5 322 1.2E-116 T 23-04-2016 IPR009323 Protein of unknown function DUF979 DC74_RS22130 154508ac5f7d74681c70fa3648ebc46b 286 Pfam PF00482 Type II secretion system (T2SS), protein F 147 268 3.2E-13 T 23-04-2016 IPR018076 Type II secretion system F domain DC74_RS16905 b773740d309e2707831b009b12efcb3a 436 Pfam PF01882 Protein of unknown function DUF58 192 277 1.1E-18 T 23-04-2016 IPR002881 Domain of unknown function DUF58 DC74_RS16905 b773740d309e2707831b009b12efcb3a 436 PANTHER PTHR33608:SF3 9 436 2.7E-151 T 23-04-2016 DC74_RS16905 b773740d309e2707831b009b12efcb3a 436 PANTHER PTHR33608 9 436 2.7E-151 T 23-04-2016 DC74_RS04585 43bdc410b5763b05d179ed8bb726abea 185 SUPERFAMILY SSF69118 3 167 3.8E-13 T 23-04-2016 IPR029032 AhpD-like DC74_RS04585 43bdc410b5763b05d179ed8bb726abea 185 Gene3D G3DSA:1.20.1290.10 33 166 4.8E-10 T 23-04-2016 IPR029032 AhpD-like DC74_RS19705 ac44081e085bd8d2aab31d18a1814b73 265 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 25 161 6.3E-20 T 23-04-2016 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 DC74_RS19705 ac44081e085bd8d2aab31d18a1814b73 265 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 22 236 3.4E-23 T 23-04-2016 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type DC74_RS19705 ac44081e085bd8d2aab31d18a1814b73 265 Gene3D G3DSA:1.20.120.450 16 105 1.7E-7 T 23-04-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase DC74_RS19705 ac44081e085bd8d2aab31d18a1814b73 265 SUPERFAMILY SSF109854 13 166 1.41E-20 T 23-04-2016 DC74_RS01840 b4d3aae6c3f786d35a86bbe278851dc1 522 PANTHER PTHR10110 4 400 1.6E-72 T 23-04-2016 IPR018422 Cation/H+ exchanger, CPA1 family GO:0006812|GO:0015299|GO:0016021 Reactome: REACT_15518 DC74_RS01840 b4d3aae6c3f786d35a86bbe278851dc1 522 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 519 1.8E-104 T 23-04-2016 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 DC74_RS01840 b4d3aae6c3f786d35a86bbe278851dc1 522 Pfam PF00999 Sodium/hydrogen exchanger family 8 400 6.1E-62 T 23-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 DC74_RS05415 2d5e7cbfdd1e2f3694ce91cd00bd52a4 446 SUPERFAMILY SSF51126 282 343 6.28E-37 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS05415 2d5e7cbfdd1e2f3694ce91cd00bd52a4 446 SUPERFAMILY SSF51126 44 251 6.28E-37 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor DC74_RS05415 2d5e7cbfdd1e2f3694ce91cd00bd52a4 446 SMART SM00710 291 313 24.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS05415 2d5e7cbfdd1e2f3694ce91cd00bd52a4 446 SMART SM00710 226 247 1300.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS05415 2d5e7cbfdd1e2f3694ce91cd00bd52a4 446 SMART SM00710 108 130 0.54 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS05415 2d5e7cbfdd1e2f3694ce91cd00bd52a4 446 SMART SM00710 256 290 6500.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS05415 2d5e7cbfdd1e2f3694ce91cd00bd52a4 446 SMART SM00710 155 177 3800.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS05415 2d5e7cbfdd1e2f3694ce91cd00bd52a4 446 SMART SM00710 178 200 12.0 T 23-04-2016 IPR006626 Parallel beta-helix repeat DC74_RS05415 2d5e7cbfdd1e2f3694ce91cd00bd52a4 446 Pfam PF13229 Right handed beta helix region 159 323 4.3E-13 T 23-04-2016 DC74_RS05415 2d5e7cbfdd1e2f3694ce91cd00bd52a4 446 Gene3D G3DSA:2.160.20.10 49 338 4.3E-28 T 23-04-2016 IPR012334 Pectin lyase fold DC74_RS00925 28fea2da5ab4d9f2b9f90eb79b3a16c0 292 Gene3D G3DSA:3.40.630.30 151 279 1.4E-15 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS00925 28fea2da5ab4d9f2b9f90eb79b3a16c0 292 SUPERFAMILY SSF55729 98 282 5.6E-15 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS28770 2db2ab253938ab7770e57d044b081178 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 61 3.4E-30 T 23-04-2016 IPR021408 Protein of unknown function DUF3046 DC74_RS02665 bba165f366a71cd57214ee611d20c073 280 PIRSF PIRSF017393 3 280 9.0E-100 T 23-04-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type DC74_RS02665 bba165f366a71cd57214ee611d20c073 280 SUPERFAMILY SSF53335 22 258 4.53E-40 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS02665 bba165f366a71cd57214ee611d20c073 280 Pfam PF04672 S-adenosyl methyltransferase 14 279 8.3E-103 T 23-04-2016 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type DC74_RS02665 bba165f366a71cd57214ee611d20c073 280 Gene3D G3DSA:3.40.50.150 7 279 3.7E-108 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS00830 7ede77617587e889f48623ddafbac234 287 SUPERFAMILY SSF53474 13 287 7.61E-31 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS00830 7ede77617587e889f48623ddafbac234 287 Pfam PF12697 Alpha/beta hydrolase family 17 284 7.3E-22 T 23-04-2016 IPR000073 Alpha/beta hydrolase fold-1 DC74_RS00830 7ede77617587e889f48623ddafbac234 287 PANTHER PTHR10992 79 287 1.5E-23 T 23-04-2016 DC74_RS00830 7ede77617587e889f48623ddafbac234 287 PANTHER PTHR10992 16 59 1.5E-23 T 23-04-2016 DC74_RS00830 7ede77617587e889f48623ddafbac234 287 Gene3D G3DSA:3.40.50.1820 16 286 2.3E-46 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS05840 e00d340819026e5aa29e525def00702a 266 Pfam PF00583 Acetyltransferase (GNAT) family 182 254 8.5E-9 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS05840 e00d340819026e5aa29e525def00702a 266 SUPERFAMILY SSF55729 38 262 1.42E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS05840 e00d340819026e5aa29e525def00702a 266 Gene3D G3DSA:3.40.630.30 136 259 2.0E-15 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS00660 43a9ac3e59bd16d3b3d286fe9397b79f 118 SMART SM01022 11 117 2.6E-5 T 23-04-2016 IPR007374 ASCH domain DC74_RS00660 43a9ac3e59bd16d3b3d286fe9397b79f 118 Gene3D G3DSA:3.10.480.10 7 116 1.2E-30 T 23-04-2016 DC74_RS00660 43a9ac3e59bd16d3b3d286fe9397b79f 118 SUPERFAMILY SSF88697 8 117 2.36E-19 T 23-04-2016 IPR015947 PUA-like domain DC74_RS00660 43a9ac3e59bd16d3b3d286fe9397b79f 118 Pfam PF04266 ASCH domain 13 117 3.4E-10 T 23-04-2016 IPR007374 ASCH domain DC74_RS01435 d81a1222a3f519e396011b4ba91e777f 164 PANTHER PTHR34297:SF1 37 156 8.2E-38 T 23-04-2016 DC74_RS01435 d81a1222a3f519e396011b4ba91e777f 164 Pfam PF03780 Asp23 family, cell envelope-related function 38 148 6.9E-31 T 23-04-2016 IPR005531 Alkaline shock protein Asp23 DC74_RS01435 d81a1222a3f519e396011b4ba91e777f 164 PANTHER PTHR34297 37 156 8.2E-38 T 23-04-2016 DC74_RS03190 f91451c8d652d488e3b00f242dccab0e 386 Pfam PF04188 Mannosyltransferase (PIG-V) 58 209 6.7E-10 T 23-04-2016 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 KEGG: 00051+2.4.1.-|KEGG: 00512+2.4.1.-|KEGG: 00513+2.4.1.-|KEGG: 00514+2.4.1.-|KEGG: 00522+2.4.1.-|KEGG: 00533+2.4.1.-|KEGG: 00540+2.4.1.-|KEGG: 00550+2.4.1.-|KEGG: 00561+2.4.1.-|KEGG: 00563+2.4.1.-|KEGG: 00600+2.4.1.-|KEGG: 00601+2.4.1.-|KEGG: 00603+2.4.1.-|KEGG: 00604+2.4.1.-|KEGG: 00906+2.4.1.-|KEGG: 00908+2.4.1.-|KEGG: 00941+2.4.1.-|KEGG: 00942+2.4.1.-|KEGG: 00944+2.4.1.-|KEGG: 00945+2.4.1.-|KEGG: 00965+2.4.1.-|UniPathway: UPA00196 DC74_RS03190 f91451c8d652d488e3b00f242dccab0e 386 PANTHER PTHR12468:SF2 54 218 1.3E-17 T 23-04-2016 DC74_RS03190 f91451c8d652d488e3b00f242dccab0e 386 PANTHER PTHR12468 54 218 1.3E-17 T 23-04-2016 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 KEGG: 00051+2.4.1.-|KEGG: 00512+2.4.1.-|KEGG: 00513+2.4.1.-|KEGG: 00514+2.4.1.-|KEGG: 00522+2.4.1.-|KEGG: 00533+2.4.1.-|KEGG: 00540+2.4.1.-|KEGG: 00550+2.4.1.-|KEGG: 00561+2.4.1.-|KEGG: 00563+2.4.1.-|KEGG: 00600+2.4.1.-|KEGG: 00601+2.4.1.-|KEGG: 00603+2.4.1.-|KEGG: 00604+2.4.1.-|KEGG: 00906+2.4.1.-|KEGG: 00908+2.4.1.-|KEGG: 00941+2.4.1.-|KEGG: 00942+2.4.1.-|KEGG: 00944+2.4.1.-|KEGG: 00945+2.4.1.-|KEGG: 00965+2.4.1.-|UniPathway: UPA00196 DC74_RS25255 81c619176122ffb44a5132d566ee6a43 138 Pfam PF14155 Domain of unknown function (DUF4307) 22 130 1.1E-30 T 23-04-2016 IPR025443 Protein of unknown function DUF4307 DC74_RS09965 8aed66796326f2f7ccf9c2fba0791cd9 150 Gene3D G3DSA:3.40.630.30 19 136 1.5E-23 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS09965 8aed66796326f2f7ccf9c2fba0791cd9 150 Pfam PF00583 Acetyltransferase (GNAT) family 64 129 1.3E-9 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS09965 8aed66796326f2f7ccf9c2fba0791cd9 150 SUPERFAMILY SSF55729 21 133 1.39E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS30535 d26fb50b23c354f61fb00cae0b61d687 159 SUPERFAMILY SSF143011 10 74 5.36E-6 T 23-04-2016 DC74_RS29640 0db49ee82e8010b413727cf1164308e6 293 Pfam PF10935 Protein of unknown function (DUF2637) 32 144 7.2E-12 T 23-04-2016 IPR021235 Protein of unknown function DUF2637 DC74_RS05040 ffbf503f6fd385f628be05bb343d1157 155 Pfam PF07681 DoxX 15 93 8.8E-6 T 23-04-2016 IPR032808 DoxX family DC74_RS38930 f8fe1dde4e8560f19eec89b688d7bfb3 114 Pfam PF11239 Protein of unknown function (DUF3040) 1 89 8.1E-10 T 23-04-2016 IPR021401 Protein of unknown function DUF3040 DC74_RS23955 c3fc23b12d1ec081758c6f915b2a9e66 463 Gene3D G3DSA:1.25.40.10 343 421 4.1E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS23955 c3fc23b12d1ec081758c6f915b2a9e66 463 Gene3D G3DSA:1.25.40.10 227 249 4.1E-4 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS09195 c6a0ea0cb2b9fb0d096992aa8185c466 156 Pfam PF10756 Bacterial PH domain 72 143 8.6E-16 T 23-04-2016 IPR019692 Protein of unknown function DUF2581 DC74_RS07120 b6a1ca27cc6df067f86852a4b4d42d2f 156 SUPERFAMILY SSF110087 14 154 4.58E-21 T 23-04-2016 IPR007410 DR1885-like metal-binding protein DC74_RS07120 b6a1ca27cc6df067f86852a4b4d42d2f 156 Pfam PF04314 Protein of unknown function (DUF461) 48 147 5.2E-18 T 23-04-2016 IPR007410 DR1885-like metal-binding protein DC74_RS39015 088474ac15fc8f17d9736783cb00f3d4 128 Pfam PF04138 GtrA-like protein 8 124 6.1E-9 T 23-04-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 DC74_RS37355 0b5add15100a2592bc5fa035c2b29afc 464 PANTHER PTHR32468 11 431 9.8E-57 T 23-04-2016 DC74_RS37355 0b5add15100a2592bc5fa035c2b29afc 464 Pfam PF00999 Sodium/hydrogen exchanger family 17 427 1.1E-41 T 23-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 DC74_RS26540 41c1c6677dca47be21d14eea3e1a9fec 134 SUPERFAMILY SSF54593 8 131 4.3E-23 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS26540 41c1c6677dca47be21d14eea3e1a9fec 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 127 1.8E-11 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS26540 41c1c6677dca47be21d14eea3e1a9fec 134 PANTHER PTHR36503 6 132 4.1E-44 T 23-04-2016 DC74_RS26540 41c1c6677dca47be21d14eea3e1a9fec 134 Gene3D G3DSA:3.10.180.10 7 133 2.0E-32 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS26540 41c1c6677dca47be21d14eea3e1a9fec 134 PANTHER PTHR36503:SF3 6 132 4.1E-44 T 23-04-2016 DC74_RS15995 7cbe896c61dfa4e5401922e01ab815d7 102 Pfam PF03777 Small secreted domain (DUF320) 49 101 9.7E-26 T 23-04-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species DC74_RS36785 3e9b17ada410996668290a0abcc424bd 265 SUPERFAMILY SSF161098 62 246 5.49E-33 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS36785 3e9b17ada410996668290a0abcc424bd 265 PANTHER PTHR30151 5 264 2.4E-75 T 23-04-2016 DC74_RS36785 3e9b17ada410996668290a0abcc424bd 265 Gene3D G3DSA:1.10.3720.10 58 255 1.1E-24 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS36785 3e9b17ada410996668290a0abcc424bd 265 PANTHER PTHR30151:SF8 5 264 2.4E-75 T 23-04-2016 DC74_RS36785 3e9b17ada410996668290a0abcc424bd 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 253 1.1E-26 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 DC74_RS01475 dbb7ab0184f1e9f2eeaf32c85547c1af 230 PANTHER PTHR12725 1 230 1.3E-56 T 23-04-2016 DC74_RS01475 dbb7ab0184f1e9f2eeaf32c85547c1af 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 5.3E-12 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS01475 dbb7ab0184f1e9f2eeaf32c85547c1af 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 5.3E-12 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS01475 dbb7ab0184f1e9f2eeaf32c85547c1af 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 5.3E-12 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS01475 dbb7ab0184f1e9f2eeaf32c85547c1af 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 188 201 5.3E-12 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS01475 dbb7ab0184f1e9f2eeaf32c85547c1af 230 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 7 204 4.6E-52 T 23-04-2016 IPR006328 Haloacid dehalogenase, type II GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 DC74_RS01475 dbb7ab0184f1e9f2eeaf32c85547c1af 230 Pfam PF13242 HAD-hyrolase-like 156 208 4.9E-5 T 23-04-2016 DC74_RS01475 dbb7ab0184f1e9f2eeaf32c85547c1af 230 SUPERFAMILY SSF56784 7 227 3.95E-34 T 23-04-2016 IPR023214 HAD-like domain DC74_RS01475 dbb7ab0184f1e9f2eeaf32c85547c1af 230 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 9 191 1.7E-34 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 DC74_RS01475 dbb7ab0184f1e9f2eeaf32c85547c1af 230 Gene3D G3DSA:3.40.50.1000 95 225 2.5E-26 T 23-04-2016 IPR023214 HAD-like domain DC74_RS01475 dbb7ab0184f1e9f2eeaf32c85547c1af 230 PANTHER PTHR12725:SF66 1 230 1.3E-56 T 23-04-2016 DC74_RS20975 b92594379b61e5a799dff902cc0d5bd5 445 PANTHER PTHR41771:SF1 20 427 2.6E-95 T 23-04-2016 DC74_RS20975 b92594379b61e5a799dff902cc0d5bd5 445 Pfam PF07907 YibE/F-like protein 173 410 1.7E-69 T 23-04-2016 IPR012507 YibE/F-like DC74_RS20975 b92594379b61e5a799dff902cc0d5bd5 445 PANTHER PTHR41771 20 427 2.6E-95 T 23-04-2016 DC74_RS33295 396f09316f56db2d61737ae1d2ea743c 385 SUPERFAMILY SSF56059 225 343 1.06E-6 T 23-04-2016 DC74_RS33295 396f09316f56db2d61737ae1d2ea743c 385 SUPERFAMILY SSF56059 133 199 1.06E-6 T 23-04-2016 DC74_RS36985 d57ce5628ea6aa32c3277cc3e2692b61 120 Pfam PF13564 DoxX-like family 8 110 5.0E-21 T 23-04-2016 IPR032808 DoxX family DC74_RS07045 10f42ba27db3ca85fc9791ba2e257fda 349 SUPERFAMILY SSF144052 143 278 2.49E-6 T 23-04-2016 DC74_RS39895 ea30869913df3f860594323e59f31c71 309 SUPERFAMILY SSF56112 37 283 9.18E-21 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS39895 ea30869913df3f860594323e59f31c71 309 Pfam PF01636 Phosphotransferase enzyme family 43 245 2.2E-11 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase DC74_RS39895 ea30869913df3f860594323e59f31c71 309 Gene3D G3DSA:3.90.1200.10 129 243 7.7E-8 T 23-04-2016 DC74_RS32935 b1ccda83681c047589ff31fd2cc65cf9 753 PANTHER PTHR30509 397 575 1.7E-13 T 23-04-2016 DC74_RS32935 b1ccda83681c047589ff31fd2cc65cf9 753 Pfam PF13515 Fusaric acid resistance protein-like 417 541 5.3E-20 T 23-04-2016 DC74_RS39415 0eaedd1cafadb3c7bb73363bf9b47238 182 PANTHER PTHR33606:SF3 1 148 5.5E-47 T 23-04-2016 DC74_RS39415 0eaedd1cafadb3c7bb73363bf9b47238 182 SUPERFAMILY SSF54909 1 89 1.15E-14 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS39415 0eaedd1cafadb3c7bb73363bf9b47238 182 PANTHER PTHR33606 1 148 5.5E-47 T 23-04-2016 DC74_RS39415 0eaedd1cafadb3c7bb73363bf9b47238 182 Pfam PF03795 YCII-related domain 1 88 3.6E-15 T 23-04-2016 IPR005545 YCII-related DC74_RS39415 0eaedd1cafadb3c7bb73363bf9b47238 182 Gene3D G3DSA:3.30.70.1060 1 90 1.3E-17 T 23-04-2016 DC74_RS37920 cd7324508462ec0cc229daaf0d745695 143 Gene3D G3DSA:1.10.357.10 13 131 1.4E-5 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS19360 3a7d161d93af8e9c5449f17670a684cd 111 PANTHER PTHR36116:SF1 1 111 1.6E-49 T 23-04-2016 DC74_RS19360 3a7d161d93af8e9c5449f17670a684cd 111 PANTHER PTHR36116 1 111 1.6E-49 T 23-04-2016 DC74_RS19360 3a7d161d93af8e9c5449f17670a684cd 111 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 109 21.282 T 23-04-2016 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 DC74_RS19360 3a7d161d93af8e9c5449f17670a684cd 111 SUPERFAMILY SSF103481 10 109 1.44E-9 T 23-04-2016 DC74_RS19360 3a7d161d93af8e9c5449f17670a684cd 111 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 4 110 3.0E-44 T 23-04-2016 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 DC74_RS19305 607b6a0c05addef2c868b40dd517f3b0 253 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 26 232 1.3E-52 T 23-04-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 DC74_RS19305 607b6a0c05addef2c868b40dd517f3b0 253 PANTHER PTHR31272:SF4 1 244 1.5E-77 T 23-04-2016 DC74_RS19305 607b6a0c05addef2c868b40dd517f3b0 253 PANTHER PTHR31272 1 244 1.5E-77 T 23-04-2016 DC74_RS13890 a1b17585990d95c6123eaa6d681a1178 177 Pfam PF14325 Domain of unknown function (DUF4383) 34 148 2.1E-11 T 23-04-2016 IPR025492 Protein of unknown function DUF4383 DC74_RS33190 fe2d92d33516def38f928752d4aefb8c 242 Pfam PF01066 CDP-alcohol phosphatidyltransferase 32 96 3.4E-9 T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DC74_RS03110 9371ce3d863b1c90098079790a54193d 431 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 221 232 - T 23-04-2016 IPR000169 Cysteine peptidase, cysteine active site DC74_RS03110 9371ce3d863b1c90098079790a54193d 431 Pfam PF00648 Calpain family cysteine protease 211 407 5.0E-16 T 23-04-2016 IPR001300 Peptidase C2, calpain, catalytic domain GO:0004198|GO:0005622|GO:0006508 DC74_RS03110 9371ce3d863b1c90098079790a54193d 431 SUPERFAMILY SSF54001 211 412 3.53E-23 T 23-04-2016 DC74_RS30335 f4f4d901fde9276f164c18c4f1082470 162 Pfam PF03771 Domain of unknown function (DUF317) 67 126 4.1E-9 T 23-04-2016 IPR005523 Domain of unknown function DUF317 DC74_RS22935 e47b1e6a0cc2b6ff5fe39bfa06fc698c 206 PANTHER PTHR37298 1 206 6.4E-79 T 23-04-2016 DC74_RS22935 e47b1e6a0cc2b6ff5fe39bfa06fc698c 206 Pfam PF01865 Protein of unknown function DUF47 7 203 1.2E-29 T 23-04-2016 IPR018445 Putative phosphate transport regulator DC74_RS17015 7a5881510e3c445f8aa79b67142b30c4 449 PRINTS PR01217 Proline rich extensin signature 179 204 8.5E-9 T 23-04-2016 DC74_RS17015 7a5881510e3c445f8aa79b67142b30c4 449 PRINTS PR01217 Proline rich extensin signature 136 153 8.5E-9 T 23-04-2016 DC74_RS17015 7a5881510e3c445f8aa79b67142b30c4 449 PRINTS PR01217 Proline rich extensin signature 70 91 8.5E-9 T 23-04-2016 DC74_RS17015 7a5881510e3c445f8aa79b67142b30c4 449 PRINTS PR01217 Proline rich extensin signature 53 65 8.5E-9 T 23-04-2016 DC74_RS17015 7a5881510e3c445f8aa79b67142b30c4 449 PRINTS PR01217 Proline rich extensin signature 23 39 8.5E-9 T 23-04-2016 DC74_RS35670 b39c4b037bea6bbe295e94886ad9c98e 319 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 42 283 1.1E-83 T 23-04-2016 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related DC74_RS03650 71ba00b3d3db2c4c77c26b25ff6b4ef0 372 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 328 363 0.0023 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain DC74_RS38405 8e2e001da1788e4ae294ceeb645e75e5 209 PANTHER PTHR32479:SF11 98 208 1.6E-27 T 23-04-2016 DC74_RS38405 8e2e001da1788e4ae294ceeb645e75e5 209 SUPERFAMILY SSF100950 44 208 5.02E-38 T 23-04-2016 DC74_RS38405 8e2e001da1788e4ae294ceeb645e75e5 209 Gene3D G3DSA:3.40.50.10420 44 208 5.8E-49 T 23-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain DC74_RS38405 8e2e001da1788e4ae294ceeb645e75e5 209 PANTHER PTHR32479 98 208 1.6E-27 T 23-04-2016 DC74_RS38405 8e2e001da1788e4ae294ceeb645e75e5 209 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 49 208 1.9E-20 T 23-04-2016 IPR003741 LUD domain DC74_RS00205 193b903e62fc66734f9e99e15b1cc201 959 Pfam PF13032 Domain of unknown function (DUF3893) 767 914 3.7E-29 T 23-04-2016 IPR024996 Domain of unknown function DUF3893 DC74_RS32315 bd8ae56ec8918bea8d8bc7d085c74f4c 315 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 159 308 1.0E-7 T 23-04-2016 IPR019587 Polyketide cyclase/dehydrase DC74_RS32315 bd8ae56ec8918bea8d8bc7d085c74f4c 315 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 8 149 5.5E-12 T 23-04-2016 IPR019587 Polyketide cyclase/dehydrase DC74_RS32315 bd8ae56ec8918bea8d8bc7d085c74f4c 315 SUPERFAMILY SSF55961 159 313 1.86E-30 T 23-04-2016 DC74_RS32315 bd8ae56ec8918bea8d8bc7d085c74f4c 315 Gene3D G3DSA:3.30.530.20 8 117 3.5E-10 T 23-04-2016 IPR023393 START-like domain DC74_RS32315 bd8ae56ec8918bea8d8bc7d085c74f4c 315 Gene3D G3DSA:3.30.530.20 161 277 1.9E-7 T 23-04-2016 IPR023393 START-like domain DC74_RS32315 bd8ae56ec8918bea8d8bc7d085c74f4c 315 SUPERFAMILY SSF55961 8 150 4.04E-35 T 23-04-2016 DC74_RS20290 a3dc31e650bbb5509cc70d0c0b5c167d 274 Pfam PF14016 Protein of unknown function (DUF4232) 137 265 1.2E-20 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS26105 293ab4be8414d477d50b76e76502cc33 270 SUPERFAMILY SSF55486 126 259 2.53E-14 T 23-04-2016 DC74_RS26105 293ab4be8414d477d50b76e76502cc33 270 Pfam PF11350 Protein of unknown function (DUF3152) 87 267 6.6E-57 T 23-04-2016 IPR022603 Domain of unknown function DUF3152 DC74_RS38835 42da9117b2fcd6895b7488818cea9dad 334 PANTHER PTHR10696 31 318 7.8E-45 T 23-04-2016 DC74_RS38835 42da9117b2fcd6895b7488818cea9dad 334 SUPERFAMILY SSF51197 28 316 5.04E-67 T 23-04-2016 DC74_RS38835 42da9117b2fcd6895b7488818cea9dad 334 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 29 314 1.1E-38 T 23-04-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 DC74_RS38835 42da9117b2fcd6895b7488818cea9dad 334 PANTHER PTHR10696:SF27 31 318 7.8E-45 T 23-04-2016 DC74_RS38835 42da9117b2fcd6895b7488818cea9dad 334 Gene3D G3DSA:3.60.130.10 197 319 5.7E-57 T 23-04-2016 DC74_RS38835 42da9117b2fcd6895b7488818cea9dad 334 Gene3D G3DSA:3.60.130.10 23 165 5.7E-57 T 23-04-2016 DC74_RS33775 00abf976bd9b5777eb920ea2eb5936de 177 Gene3D G3DSA:3.90.1720.10 63 170 5.4E-7 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- DC74_RS01280 96b011414f30e308693df4106f182b24 135 Pfam PF05121 Gas vesicle protein K 47 131 2.0E-34 T 23-04-2016 IPR007805 Gas vesicle protein GvpK GO:0031412 DC74_RS01280 96b011414f30e308693df4106f182b24 135 PANTHER PTHR40137 34 135 1.3E-42 T 23-04-2016 DC74_RS01280 96b011414f30e308693df4106f182b24 135 PANTHER PTHR40137:SF1 34 135 1.3E-42 T 23-04-2016 DC74_RS16275 d5f6b219dec9d75a720337838a3f7499 264 Pfam PF06182 ABC-2 family transporter protein 39 258 1.8E-16 T 23-04-2016 IPR010390 Protein of unknown function DUF990 DC74_RS16275 d5f6b219dec9d75a720337838a3f7499 264 PANTHER PTHR36832:SF2 2 264 2.8E-107 T 23-04-2016 DC74_RS16275 d5f6b219dec9d75a720337838a3f7499 264 PANTHER PTHR36832 2 264 2.8E-107 T 23-04-2016 DC74_RS24195 ae174f8225f9067ed4b4a6f17bbc71b8 298 Pfam PF05709 Phage tail protein 41 277 9.5E-5 T 23-04-2016 IPR008841 Siphovirus-type tail component DC74_RS16320 be24c233c3802e2672d99ee52e482734 220 SMART SM00507 144 202 1.5E-4 T 23-04-2016 IPR003615 HNH nuclease DC74_RS16320 be24c233c3802e2672d99ee52e482734 220 Pfam PF13392 HNH endonuclease 173 197 1.0E-6 T 23-04-2016 IPR003615 HNH nuclease DC74_RS29360 592e81ffd4a830c17b45822dcac7d355 794 Gene3D G3DSA:3.50.50.60 13 53 7.6E-18 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS29360 592e81ffd4a830c17b45822dcac7d355 794 Gene3D G3DSA:3.50.50.60 107 157 7.6E-18 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS29360 592e81ffd4a830c17b45822dcac7d355 794 Pfam PF13450 NAD(P)-binding Rossmann-like domain 16 45 9.1E-5 T 23-04-2016 DC74_RS29360 592e81ffd4a830c17b45822dcac7d355 794 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 13 35 1.4E-5 T 23-04-2016 DC74_RS29360 592e81ffd4a830c17b45822dcac7d355 794 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 140 155 1.4E-5 T 23-04-2016 DC74_RS29360 592e81ffd4a830c17b45822dcac7d355 794 SUPERFAMILY SSF51905 12 161 1.94E-13 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DC74_RS09980 f3c8e562ac5e4ecabfda1e216b2fd036 69 Pfam PF08940 Domain of unknown function (DUF1918) 1 57 1.7E-24 T 23-04-2016 IPR015035 Domain of unknown function DUF1918 DC74_RS09980 f3c8e562ac5e4ecabfda1e216b2fd036 69 SUPERFAMILY SSF50118 1 63 1.5E-21 T 23-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor DC74_RS31105 b277736bef31a1e3c540f94718e75d24 160 Pfam PF04306 Protein of unknown function (DUF456) 21 156 6.6E-29 T 23-04-2016 IPR007403 Protein of unknown function DUF456 DC74_RS26230 9b524e4648b8a0f1ea4b60e7299b5cb1 203 Pfam PF01863 Protein of unknown function DUF45 111 183 1.7E-22 T 23-04-2016 IPR002725 Protein of unknown function DUF45 DC74_RS26230 9b524e4648b8a0f1ea4b60e7299b5cb1 203 PANTHER PTHR30399 15 203 1.5E-43 T 23-04-2016 DC74_RS26230 9b524e4648b8a0f1ea4b60e7299b5cb1 203 PANTHER PTHR30399:SF3 15 203 1.5E-43 T 23-04-2016 DC74_RS11215 80fbaf58007ab7b83f4fd367419960eb 260 PANTHER PTHR40053 1 260 1.9E-92 T 23-04-2016 DC74_RS11215 80fbaf58007ab7b83f4fd367419960eb 260 Pfam PF07070 SpoOM protein 3 216 1.1E-78 T 23-04-2016 IPR009776 Sporulation stage 0, protein M DC74_RS19210 d21963ce91fece11b5e805cebe03d235 95 Pfam PF14012 Protein of unknown function (DUF4229) 9 80 3.8E-23 T 23-04-2016 IPR025323 Protein of unknown function DUF4229 DC74_RS04445 c158cea61f494c2c4c5bef58a437f54d 75 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 70 5.3E-27 T 23-04-2016 IPR018735 Protein of unknown function DUF2277 DC74_RS09580 68cf5a6ccdc92ff8b1d7628b4182ee6d 409 Pfam PF03993 Domain of Unknown Function (DUF349) 91 164 1.8E-12 T 23-04-2016 IPR007139 Protein of unknown function DUF349 DC74_RS09580 68cf5a6ccdc92ff8b1d7628b4182ee6d 409 Pfam PF03993 Domain of Unknown Function (DUF349) 245 318 7.7E-22 T 23-04-2016 IPR007139 Protein of unknown function DUF349 DC74_RS09580 68cf5a6ccdc92ff8b1d7628b4182ee6d 409 Pfam PF03993 Domain of Unknown Function (DUF349) 168 241 2.5E-21 T 23-04-2016 IPR007139 Protein of unknown function DUF349 DC74_RS14450 4ce18c8610d1ba8eeb30f32ce56d4bf7 68 Pfam PF04149 Domain of unknown function (DUF397) 12 62 3.2E-21 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS09175 74c5ae3bdca30c6022cff7e800f055e3 198 Gene3D G3DSA:3.40.50.300 24 184 3.5E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS09175 74c5ae3bdca30c6022cff7e800f055e3 198 SUPERFAMILY SSF52540 27 179 3.62E-15 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS13690 0d8d124a27aa3fbfdbfcef2bdee3348e 291 Pfam PF12822 Protein of unknown function (DUF3816) 77 259 1.6E-16 T 23-04-2016 IPR024529 ECF transporter, substrate-specific component GO:0005215 DC74_RS13690 0d8d124a27aa3fbfdbfcef2bdee3348e 291 PIRSF PIRSF037395 7 283 3.8E-109 T 23-04-2016 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 DC74_RS11695 c94f1a00d3de51e005def535fadafd1d 187 SUPERFAMILY SSF48498 89 178 7.91E-8 T 23-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal DC74_RS11695 c94f1a00d3de51e005def535fadafd1d 187 PANTHER PTHR30055:SF2 9 178 2.8E-21 T 23-04-2016 DC74_RS11695 c94f1a00d3de51e005def535fadafd1d 187 Gene3D G3DSA:1.10.357.10 8 177 3.6E-33 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS11695 c94f1a00d3de51e005def535fadafd1d 187 SUPERFAMILY SSF46689 3 81 2.41E-16 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 DC74_RS11695 c94f1a00d3de51e005def535fadafd1d 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 3.9E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DC74_RS11695 c94f1a00d3de51e005def535fadafd1d 187 PANTHER PTHR30055 9 178 2.8E-21 T 23-04-2016 DC74_RS14065 a96455951b4b14dad0d3488f958237b1 233 Pfam PF13349 Putative adhesin 44 229 1.6E-10 T 23-04-2016 IPR025164 Putative adhesin DC74_RS23305 e60f009749ef3ad20def87fcc225c950 205 SUPERFAMILY SSF110087 45 156 3.92E-7 T 23-04-2016 IPR007410 DR1885-like metal-binding protein DC74_RS22975 cc1a66ee0d153b3973d99581aa03610d 117 Pfam PF10724 Protein of unknown function (DUF2516) 10 95 8.5E-25 T 23-04-2016 IPR019662 Protein of unknown function DUF2516 DC74_RS32730 21b76f8d28cb0a70a3e38855b42a1463 118 Gene3D G3DSA:1.10.357.10 19 107 9.0E-13 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 DC74_RS06105 966fc6cd440e06ef0b14d934770b1a23 361 PANTHER PTHR23024 106 351 1.0E-61 T 23-04-2016 DC74_RS06105 966fc6cd440e06ef0b14d934770b1a23 361 SUPERFAMILY SSF53474 98 350 2.54E-57 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS06105 966fc6cd440e06ef0b14d934770b1a23 361 Gene3D G3DSA:3.40.50.1820 28 350 6.1E-73 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS06105 966fc6cd440e06ef0b14d934770b1a23 361 Pfam PF07859 alpha/beta hydrolase fold 118 325 6.6E-53 T 23-04-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 DC74_RS13865 004da7a7e3411acfe814dc9bf7926b12 183 Pfam PF07681 DoxX 29 112 1.4E-17 T 23-04-2016 IPR032808 DoxX family DC74_RS13865 004da7a7e3411acfe814dc9bf7926b12 183 PANTHER PTHR33452:SF1 28 153 5.8E-34 T 23-04-2016 DC74_RS13865 004da7a7e3411acfe814dc9bf7926b12 183 PANTHER PTHR33452 28 153 5.8E-34 T 23-04-2016 DC74_RS08770 99045259d7fbd66857ede44b6ec9cd17 157 Gene3D G3DSA:3.30.530.20 18 156 1.8E-15 T 23-04-2016 IPR023393 START-like domain DC74_RS08770 99045259d7fbd66857ede44b6ec9cd17 157 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 21 154 2.5E-22 T 23-04-2016 IPR019587 Polyketide cyclase/dehydrase DC74_RS08770 99045259d7fbd66857ede44b6ec9cd17 157 SUPERFAMILY SSF55961 19 155 1.43E-20 T 23-04-2016 DC74_RS01270 19389a8e79f70ba3924de807fb4ecd6f 185 SUPERFAMILY SSF54909 16 122 1.61E-14 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS01270 19389a8e79f70ba3924de807fb4ecd6f 185 Pfam PF11695 Domain of unknown function (DUF3291) 11 148 2.8E-54 T 23-04-2016 IPR021708 Domain of unknown function DUF3291 DC74_RS17460 e366415d33e4ea242314685c847cf939 933 Pfam PF14435 SUKH-4 immunity protein 751 927 9.2E-45 T 23-04-2016 IPR025851 SUKH-4 immunity protein DC74_RS17460 e366415d33e4ea242314685c847cf939 933 Pfam PF14440 Xanthomonas XOO_2897-like deaminase 611 710 4.7E-33 T 23-04-2016 IPR032722 Deaminase, Xanthomonas XOO_2897-like DC74_RS16735 10417d232f9d63f8c9a1119b19ace3f4 331 Pfam PF13578 Methyltransferase domain 51 172 5.5E-13 T 23-04-2016 DC74_RS16735 10417d232f9d63f8c9a1119b19ace3f4 331 SUPERFAMILY SSF53335 34 178 8.57E-9 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS16735 10417d232f9d63f8c9a1119b19ace3f4 331 Gene3D G3DSA:3.40.50.150 47 174 8.4E-7 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS30110 ac4207e8edeb5d2a21068fa61a73f598 603 TIGRFAM TIGR01863 cas_Csd1: CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG 10 579 5.8E-81 T 23-04-2016 IPR010144 CRISPR-associated protein, Csd1-type DC74_RS30110 ac4207e8edeb5d2a21068fa61a73f598 603 Pfam PF09709 CRISPR-associated protein (Cas_Csd1) 11 574 2.1E-91 T 23-04-2016 IPR010144 CRISPR-associated protein, Csd1-type DC74_RS18935 d9f85f96feb6d157484c4c3433df908a 133 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 33 132 1.6E-29 T 23-04-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 DC74_RS18935 d9f85f96feb6d157484c4c3433df908a 133 PANTHER PTHR11058 5 133 1.1E-40 T 23-04-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 DC74_RS18935 d9f85f96feb6d157484c4c3433df908a 133 PANTHER PTHR11058:SF9 5 133 1.1E-40 T 23-04-2016 DC74_RS14635 a04173efccac7bad4cab2a8fb12030d0 151 Gene3D G3DSA:3.10.490.10 9 146 3.8E-24 T 23-04-2016 IPR013024 Butirosin biosynthesis, BtrG-like DC74_RS14635 a04173efccac7bad4cab2a8fb12030d0 151 SUPERFAMILY SSF110857 9 143 1.44E-19 T 23-04-2016 IPR013024 Butirosin biosynthesis, BtrG-like DC74_RS14635 a04173efccac7bad4cab2a8fb12030d0 151 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 10 141 3.5E-21 T 23-04-2016 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like DC74_RS09355 fd8561be328e59b9be0fb8c9a55c0116 153 Pfam PF14433 SUKH-3 immunity protein 29 146 9.4E-9 T 23-04-2016 IPR025850 SUKH-3 immunity protein DC74_RS08725 dce0a5fceffb3814502e49d60df8dee9 460 Gene3D G3DSA:2.60.60.30 15 166 1.4E-34 T 23-04-2016 DC74_RS08725 dce0a5fceffb3814502e49d60df8dee9 460 Pfam PF02342 TerD domain 2 168 1.0E-43 T 23-04-2016 IPR003325 TerD domain GO:0006950 DC74_RS08725 dce0a5fceffb3814502e49d60df8dee9 460 PANTHER PTHR32097:SF4 1 453 3.1E-123 T 23-04-2016 DC74_RS08725 dce0a5fceffb3814502e49d60df8dee9 460 PANTHER PTHR32097 1 453 3.1E-123 T 23-04-2016 DC74_RS14785 5d9f6a8fed647065f2e8f1b7eb6f784b 188 SUPERFAMILY SSF55729 27 168 8.07E-15 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS14785 5d9f6a8fed647065f2e8f1b7eb6f784b 188 Gene3D G3DSA:3.40.630.30 16 177 9.6E-16 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS14785 5d9f6a8fed647065f2e8f1b7eb6f784b 188 Pfam PF00583 Acetyltransferase (GNAT) family 69 162 1.1E-7 T 23-04-2016 IPR000182 GNAT domain GO:0008080 DC74_RS13085 92ca05afb3772cf389fd322a5bf63913 172 SUPERFAMILY SSF50090 48 111 6.28E-5 T 23-04-2016 IPR008990 Electron transport accessory protein-like domain DC74_RS13085 92ca05afb3772cf389fd322a5bf63913 172 Pfam PF14024 Protein of unknown function (DUF4240) 1 128 3.3E-47 T 23-04-2016 IPR025334 Domain of unknown function (DUF4240 DC74_RS22350 f3bae86ee73faadf7a5b2b61b221aab6 79 Pfam PF04149 Domain of unknown function (DUF397) 17 69 3.1E-17 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS40205 be45ad35cece29ec226ec7292b999325 253 Pfam PF05901 Excalibur calcium-binding domain 203 236 4.0E-5 T 23-04-2016 IPR008613 Excalibur calcium-binding domain DC74_RS05190 af053ee7a3b32023d878afea16640518 174 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 32 8.5E-6 T 23-04-2016 IPR012902 Prokaryotic N-terminal methylation site DC74_RS22095 a3fdf4cd54a8b3899554866864004fc8 423 SUPERFAMILY SSF88713 99 120 2.78E-22 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS22095 a3fdf4cd54a8b3899554866864004fc8 423 SUPERFAMILY SSF88713 150 379 2.78E-22 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DC74_RS22095 a3fdf4cd54a8b3899554866864004fc8 423 Gene3D G3DSA:3.20.20.370 99 378 1.6E-8 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 DC74_RS02655 93a51d2b8618b482aaa27f62e8f48b39 78 Pfam PF04149 Domain of unknown function (DUF397) 16 69 3.6E-20 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS18975 5cc3acd672af9403429d1c8a56906365 296 Pfam PF12679 ABC-2 family transporter protein 29 236 1.3E-10 T 23-04-2016 IPR032688 ABC-2 family transporter protein GO:0006810 DC74_RS26055 5f01cfff9f03a9db256c4029d5d8f34d 308 Gene3D G3DSA:3.40.50.1010 37 182 6.5E-16 T 23-04-2016 IPR029060 PIN domain-like DC74_RS26055 5f01cfff9f03a9db256c4029d5d8f34d 308 Pfam PF01936 NYN domain 41 183 6.3E-11 T 23-04-2016 IPR021139 NYN domain, limkain-b1-type DC74_RS39445 99eae3cd5fae3d90664d7d79bec2ff5d 190 Pfam PF16715 Cyclodipeptide synthase 2 183 1.3E-51 T 23-04-2016 IPR030903 Cyclodileucine synthase GO:0016755 DC74_RS39445 99eae3cd5fae3d90664d7d79bec2ff5d 190 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 2 183 3.1E-59 T 23-04-2016 IPR030903 Cyclodileucine synthase GO:0016755 DC74_RS31990 dc9808720ee9d2399db34af65460499f 364 Pfam PF06889 Protein of unknown function (DUF1266) 187 363 6.7E-32 T 23-04-2016 IPR009677 Protein of unknown function DUF1266 DC74_RS31965 cab1aaba29933699ac6c9dd393bab933 133 Gene3D G3DSA:3.10.450.50 18 130 2.7E-11 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS31965 cab1aaba29933699ac6c9dd393bab933 133 Pfam PF12680 SnoaL-like domain 20 122 6.9E-13 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS31965 cab1aaba29933699ac6c9dd393bab933 133 SUPERFAMILY SSF54427 15 128 7.93E-33 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS30675 f6321582360bff0de3b9fdb3b6710a37 575 Pfam PF03432 Relaxase/Mobilisation nuclease domain 115 230 2.1E-4 T 23-04-2016 IPR005094 Endonuclease relaxase, MobA/VirD2 DC74_RS05130 2d253afdb67fe44fd21f648cc1663d83 103 SMART SM00894 30 67 4.8E-6 T 23-04-2016 IPR008613 Excalibur calcium-binding domain DC74_RS05130 2d253afdb67fe44fd21f648cc1663d83 103 Pfam PF05901 Excalibur calcium-binding domain 32 66 5.3E-7 T 23-04-2016 IPR008613 Excalibur calcium-binding domain DC74_RS37135 59a7cc7b1d7c730a53eddd5c6b3a729b 89 Gene3D G3DSA:3.10.450.50 9 87 1.5E-6 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS37135 59a7cc7b1d7c730a53eddd5c6b3a729b 89 SUPERFAMILY SSF54427 6 81 3.28E-5 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS07305 469c66226ae6363f9bf37f8d54452f85 148 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 31 142 4.0E-38 T 23-04-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 DC74_RS07305 469c66226ae6363f9bf37f8d54452f85 148 PANTHER PTHR39428 1 144 2.2E-59 T 23-04-2016 DC74_RS07305 469c66226ae6363f9bf37f8d54452f85 148 SUPERFAMILY SSF50475 33 143 1.34E-7 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS07305 469c66226ae6363f9bf37f8d54452f85 148 Pfam PF04075 Domain of unknown function (DUF385) 14 143 2.6E-53 T 23-04-2016 IPR004378 Deazaflavin-dependent nitroreductase/F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 DC74_RS30875 5230025579788be1fdf4834ef6e31e1a 448 Pfam PF01590 GAF domain 120 233 3.8E-9 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS25495 1955558bb6322f0020a2ea1af4916d72 453 PANTHER PTHR21716 71 445 1.6E-68 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like DC74_RS25495 1955558bb6322f0020a2ea1af4916d72 453 Pfam PF01594 Domain of unknown function DUF20 90 414 8.3E-59 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like DC74_RS24315 a56161feede72fe9545e7f3bd79307ce 177 Pfam PF07681 DoxX 28 130 7.0E-17 T 23-04-2016 IPR032808 DoxX family DC74_RS24315 a56161feede72fe9545e7f3bd79307ce 177 PANTHER PTHR39157 6 170 1.3E-36 T 23-04-2016 DC74_RS38140 f1f81aa4bf471954be4d58d30e86172a 333 PANTHER PTHR21716 7 324 2.4E-44 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like DC74_RS38140 f1f81aa4bf471954be4d58d30e86172a 333 Pfam PF01594 Domain of unknown function DUF20 12 331 7.7E-43 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like DC74_RS04620 88e7dafd390a4de44a7f79181aa2f184 108 Pfam PF13586 Transposase DDE domain 7 80 2.8E-8 T 23-04-2016 IPR025668 Transposase DDE domain DC74_RS06720 efc74ca01221a07459dfb22ee191a1ba 544 Pfam PF12222 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A 52 382 1.1E-68 T 23-04-2016 IPR021102 Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A DC74_RS06720 efc74ca01221a07459dfb22ee191a1ba 544 PANTHER PTHR31104 39 415 2.6E-77 T 23-04-2016 DC74_RS40200 769df446e9ce9e086d18f506b6b8153f 85 Gene3D G3DSA:3.90.1150.10 2 82 8.9E-7 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 DC74_RS19915 87a6e8d02b6314d5c64a7dc9330fe14c 400 PANTHER PTHR12468:SF3 56 218 9.9E-35 T 23-04-2016 DC74_RS19915 87a6e8d02b6314d5c64a7dc9330fe14c 400 PANTHER PTHR12468 56 218 9.9E-35 T 23-04-2016 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 KEGG: 00051+2.4.1.-|KEGG: 00512+2.4.1.-|KEGG: 00513+2.4.1.-|KEGG: 00514+2.4.1.-|KEGG: 00522+2.4.1.-|KEGG: 00533+2.4.1.-|KEGG: 00540+2.4.1.-|KEGG: 00550+2.4.1.-|KEGG: 00561+2.4.1.-|KEGG: 00563+2.4.1.-|KEGG: 00600+2.4.1.-|KEGG: 00601+2.4.1.-|KEGG: 00603+2.4.1.-|KEGG: 00604+2.4.1.-|KEGG: 00906+2.4.1.-|KEGG: 00908+2.4.1.-|KEGG: 00941+2.4.1.-|KEGG: 00942+2.4.1.-|KEGG: 00944+2.4.1.-|KEGG: 00945+2.4.1.-|KEGG: 00965+2.4.1.-|UniPathway: UPA00196 DC74_RS39550 a927f9a889222a2b4af63074070a4314 446 Pfam PF02687 FtsX-like permease family 64 181 7.0E-7 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 DC74_RS03750 43dc22ea30718401ace34cbd4c975b27 964 Pfam PF04738 Lantibiotic dehydratase, C terminus 558 851 5.6E-11 T 23-04-2016 IPR006827 Lantibiotic dehydratase, C-terminal DC74_RS28750 ef8d8a206fb89f9f0233d4f0b94de9cb 137 Pfam PF02416 mttA/Hcf106 family 5 50 1.4E-7 T 23-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 DC74_RS29685 a5cfaf27dc4cf88e64aa46c0c15d70ad 274 Pfam PF01909 Nucleotidyltransferase domain 20 64 1.3E-5 T 23-04-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DC74_RS29685 a5cfaf27dc4cf88e64aa46c0c15d70ad 274 SUPERFAMILY SSF81301 25 74 6.0E-7 T 23-04-2016 DC74_RS29685 a5cfaf27dc4cf88e64aa46c0c15d70ad 274 Gene3D G3DSA:3.30.460.10 19 79 9.0E-9 T 23-04-2016 DC74_RS01820 c202e14a09c31ad45c3b6486a406f116 265 Pfam PF01169 Uncharacterized protein family UPF0016 144 201 1.9E-4 T 23-04-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 DC74_RS01820 c202e14a09c31ad45c3b6486a406f116 265 Pfam PF01169 Uncharacterized protein family UPF0016 8 81 2.1E-5 T 23-04-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 DC74_RS36565 9158d9cb4408de35645c6e0e93a65fb3 377 SUPERFAMILY SSF47336 303 373 1.14E-6 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS36565 9158d9cb4408de35645c6e0e93a65fb3 377 Gene3D G3DSA:1.10.1200.10 301 374 4.0E-7 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain DC74_RS34760 82d3c11cc650f760492d0ebbaa2d3d0c 429 Pfam PF01590 GAF domain 110 213 3.2E-4 T 23-04-2016 IPR003018 GAF domain GO:0005515 DC74_RS10590 a9fb6081866c44e23d85ec69d5d6e3d4 121 Pfam PF02656 Domain of unknown function (DUF202) 21 83 8.9E-11 T 23-04-2016 IPR003807 Domain of unknown function DUF202 DC74_RS30650 ff431ccd21508aa985378b9ef309a149 114 Pfam PF03771 Domain of unknown function (DUF317) 55 111 5.3E-12 T 23-04-2016 IPR005523 Domain of unknown function DUF317 DC74_RS22645 0c6565a7df3b0153ede09d657a938d61 124 SUPERFAMILY SSF55874 24 110 3.39E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS22645 0c6565a7df3b0153ede09d657a938d61 124 Pfam PF13581 Histidine kinase-like ATPase domain 18 101 3.1E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS11815 6fdcf80466e07f9ce6c3b61c959659b1 78 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 3.6E-7 T 23-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 DC74_RS11815 6fdcf80466e07f9ce6c3b61c959659b1 78 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 3.6E-7 T 23-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 DC74_RS11815 6fdcf80466e07f9ce6c3b61c959659b1 78 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 3.6E-7 T 23-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 DC74_RS11815 6fdcf80466e07f9ce6c3b61c959659b1 78 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 3.6E-7 T 23-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 DC74_RS11815 6fdcf80466e07f9ce6c3b61c959659b1 78 Pfam PF03840 Preprotein translocase SecG subunit 5 73 2.7E-20 T 23-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 DC74_RS11815 6fdcf80466e07f9ce6c3b61c959659b1 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 5 73 3.7E-21 T 23-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 DC74_RS29500 1e346a5b11048a8fa3255136ae5feafa 261 Pfam PF00975 Thioesterase domain 37 258 3.2E-35 T 23-04-2016 IPR001031 Thioesterase GO:0009058|GO:0016788 DC74_RS29500 1e346a5b11048a8fa3255136ae5feafa 261 PANTHER PTHR11487 20 257 6.0E-67 T 23-04-2016 IPR012223 Thioesterase type II, NRPS/PKS/S-FAS GO:0009058 DC74_RS29500 1e346a5b11048a8fa3255136ae5feafa 261 SUPERFAMILY SSF53474 21 251 4.82E-43 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS29500 1e346a5b11048a8fa3255136ae5feafa 261 Gene3D G3DSA:3.40.50.1820 197 249 6.1E-27 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS29500 1e346a5b11048a8fa3255136ae5feafa 261 Gene3D G3DSA:3.40.50.1820 21 142 6.1E-27 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS20970 21ea8c597eeee41f0518231ca835a198 132 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 15 112 2.1E-32 T 23-04-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 DC74_RS30445 2e577d8c92638eb1e64e714e550dce5d 598 SUPERFAMILY SSF53300 428 551 4.45E-9 T 23-04-2016 IPR002035 von Willebrand factor, type A DC74_RS19595 4b99a416c760f7073421586c0e84b06c 381 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 30 375 1.2E-73 T 23-04-2016 IPR011200 Uncharacterised conserved protein UCP012608 DC74_RS10480 3d866b3a63a3afebc9bd52b15504bf43 262 SUPERFAMILY SSF47240 17 166 5.73E-7 T 23-04-2016 IPR009078 Ferritin-like superfamily DC74_RS17730 beac34254d2270328491c41d0047a2c6 390 PANTHER PTHR11579:SF0 1 48 1.9E-35 T 23-04-2016 DC74_RS17730 beac34254d2270328491c41d0047a2c6 390 PANTHER PTHR11579:SF0 69 216 1.9E-35 T 23-04-2016 DC74_RS17730 beac34254d2270328491c41d0047a2c6 390 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 97 224 2.1E-24 T 23-04-2016 DC74_RS17730 beac34254d2270328491c41d0047a2c6 390 PANTHER PTHR11579 1 48 1.9E-35 T 23-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 DC74_RS17730 beac34254d2270328491c41d0047a2c6 390 PANTHER PTHR11579 69 216 1.9E-35 T 23-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 DC74_RS17730 beac34254d2270328491c41d0047a2c6 390 Gene3D G3DSA:3.40.50.150 21 259 3.0E-52 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS17730 beac34254d2270328491c41d0047a2c6 390 SUPERFAMILY SSF53335 100 219 5.18E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS40760 b395f8e81136002265c55faabb6a1fe5 228 Pfam PF01526 Tn3 transposase DDE domain 1 227 2.1E-78 T 23-04-2016 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 DC74_RS28950 d5b8ce161bab756ff87ca98774536c43 201 Pfam PF16291 Domain of unknown function (DUF4937 2 86 7.1E-27 T 23-04-2016 IPR032555 Domain of unknown function DUF4937 DC74_RS28950 d5b8ce161bab756ff87ca98774536c43 201 SUPERFAMILY SSF54909 16 80 9.27E-5 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS28950 d5b8ce161bab756ff87ca98774536c43 201 SUPERFAMILY SSF54909 105 164 2.19E-5 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS13560 a7cbd1e6b61188c3ddf63c542c300657 518 SUPERFAMILY SSF82171 76 318 1.02E-5 T 23-04-2016 DC74_RS19370 fdff2a941edbb3153b5e03883f9504e4 276 Pfam PF10067 Predicted membrane protein (DUF2306) 95 255 8.1E-26 T 23-04-2016 IPR018750 Protein of unknown function DUF2306, membrane DC74_RS29785 9ef2c04a2e2de36dea88ea64fe0e7104 218 Pfam PF11452 Protein of unknown function (DUF3000) 16 197 7.8E-70 T 23-04-2016 IPR021555 Protein of unknown function DUF3000 DC74_RS01240 4b90cbb699b4fa310614636e7f479e74 279 Pfam PF03988 Repeat of Unknown Function (DUF347) 212 266 9.9E-18 T 23-04-2016 IPR007136 Protein of unknown function DUF347 DC74_RS01240 4b90cbb699b4fa310614636e7f479e74 279 Pfam PF03988 Repeat of Unknown Function (DUF347) 36 87 2.6E-16 T 23-04-2016 IPR007136 Protein of unknown function DUF347 DC74_RS01240 4b90cbb699b4fa310614636e7f479e74 279 Pfam PF03988 Repeat of Unknown Function (DUF347) 156 202 1.6E-11 T 23-04-2016 IPR007136 Protein of unknown function DUF347 DC74_RS01240 4b90cbb699b4fa310614636e7f479e74 279 Pfam PF03988 Repeat of Unknown Function (DUF347) 91 142 1.0E-13 T 23-04-2016 IPR007136 Protein of unknown function DUF347 DC74_RS11255 3cd7603c832947a118167f2c090d27ca 81 Pfam PF03777 Small secreted domain (DUF320) 25 80 4.9E-24 T 23-04-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species DC74_RS20260 094e7c7e00f4b86bb0fb47ce03db98d4 386 Pfam PF01594 Domain of unknown function DUF20 40 355 1.6E-57 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like DC74_RS20260 094e7c7e00f4b86bb0fb47ce03db98d4 386 PANTHER PTHR21716 7 360 1.0E-70 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like DC74_RS05610 17be84ad7648e2e316a1c93b48e71a29 335 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 18 299 4.4E-41 T 23-04-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD DC74_RS05610 17be84ad7648e2e316a1c93b48e71a29 335 PANTHER PTHR39087 1 326 1.6E-12 T 23-04-2016 DC74_RS34280 4e93ecc0f37490262c158814ad71399c 271 PANTHER PTHR32251 2 265 1.0E-70 T 23-04-2016 DC74_RS34280 4e93ecc0f37490262c158814ad71399c 271 Pfam PF06966 Protein of unknown function (DUF1295) 28 256 7.5E-68 T 23-04-2016 IPR010721 Protein of unknown function DUF1295 DC74_RS15675 fff3fe3473d3b01ec58c2296d82372a7 286 Pfam PF12679 ABC-2 family transporter protein 22 284 7.8E-14 T 23-04-2016 IPR032688 ABC-2 family transporter protein GO:0006810 DC74_RS00840 776d6749d0dd5fc1a9a98453cb122d0a 346 SUPERFAMILY SSF53756 9 304 1.82E-14 T 23-04-2016 DC74_RS36735 2341eb2809eb042300b47e416eee2479 283 Pfam PF03988 Repeat of Unknown Function (DUF347) 45 94 4.2E-11 T 23-04-2016 IPR007136 Protein of unknown function DUF347 DC74_RS36735 2341eb2809eb042300b47e416eee2479 283 Pfam PF03988 Repeat of Unknown Function (DUF347) 218 273 6.7E-10 T 23-04-2016 IPR007136 Protein of unknown function DUF347 DC74_RS36735 2341eb2809eb042300b47e416eee2479 283 Pfam PF03988 Repeat of Unknown Function (DUF347) 98 147 2.4E-11 T 23-04-2016 IPR007136 Protein of unknown function DUF347 DC74_RS36735 2341eb2809eb042300b47e416eee2479 283 Pfam PF03988 Repeat of Unknown Function (DUF347) 163 204 2.4E-9 T 23-04-2016 IPR007136 Protein of unknown function DUF347 DC74_RS22695 1d49c5e4fe3f242becdb2e4074c5f585 137 Gene3D G3DSA:3.10.450.50 7 132 1.2E-29 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS22695 1d49c5e4fe3f242becdb2e4074c5f585 137 Pfam PF12680 SnoaL-like domain 10 117 1.7E-17 T 23-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain DC74_RS22695 1d49c5e4fe3f242becdb2e4074c5f585 137 SUPERFAMILY SSF54427 6 132 5.36E-29 T 23-04-2016 IPR032710 NTF2-like domain DC74_RS23165 c419acf3049666d88224c9de050dabf0 95 Pfam PF07210 Protein of unknown function (DUF1416) 2 95 5.6E-36 T 23-04-2016 IPR010814 Protein of unknown function DUF1416 DC74_RS23165 c419acf3049666d88224c9de050dabf0 95 Gene3D G3DSA:2.60.40.10 19 84 2.2E-6 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS05805 be97e7686b71e2098baa88aaebc8ef29 189 PANTHER PTHR30086 1 180 2.3E-30 T 23-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 DC74_RS05805 be97e7686b71e2098baa88aaebc8ef29 189 Pfam PF01810 LysE type translocator 5 184 3.0E-24 T 23-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 DC74_RS14370 efe488ab2491eeeb3975a3ca9070bba3 142 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 23 102 5.2E-6 T 23-04-2016 IPR010064 Bacteriophage HK97-gp10, putative tail-component DC74_RS27820 96b47983d50bb295b933062dacacb261 210 Pfam PF05331 Protein of unknown function (DUF742) 98 210 2.1E-40 T 23-04-2016 IPR007995 Protein of unknown function DUF742 DC74_RS27820 96b47983d50bb295b933062dacacb261 210 PANTHER PTHR36221 77 210 4.3E-41 T 23-04-2016 DC74_RS20500 9f0155de95d1631322f4f078f7bf30eb 247 PANTHER PTHR24074 1 193 3.6E-20 T 23-04-2016 DC74_RS13010 69364bbc95a2839019bee8f79be39ec4 198 Pfam PF11241 Protein of unknown function (DUF3043) 30 196 4.7E-64 T 23-04-2016 IPR021403 Protein of unknown function DUF3043 DC74_RS40745 610658da45829b0ea0c7bccb474e82aa 224 Pfam PF13700 Domain of unknown function (DUF4158) 54 127 1.5E-8 T 23-04-2016 IPR025296 Domain of unknown function DUF4158 DC74_RS30785 abdeacdd0cca804f9dd31c5a9d8787ad 62 TIGRFAM TIGR04363 LD_lanti_pre: FxLD family lantipeptide 17 56 3.7E-15 T 23-04-2016 IPR027575 FxLD family lantipeptide DC74_RS26030 2f5c701af8bebc2c162828128edf986d 194 Pfam PF05076 Suppressor of fused protein (SUFU) 29 188 3.3E-33 T 23-04-2016 IPR020941 Suppressor of fused-like domain DC74_RS17685 ca3a82c40bcdbdf08ad79c6f40ef12f8 369 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 218 3.5E-55 T 23-04-2016 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 UniPathway: UPA00148 DC74_RS17685 ca3a82c40bcdbdf08ad79c6f40ef12f8 369 PANTHER PTHR34229 2 245 2.6E-79 T 23-04-2016 DC74_RS17685 ca3a82c40bcdbdf08ad79c6f40ef12f8 369 PANTHER PTHR34229:SF1 2 245 2.6E-79 T 23-04-2016 DC74_RS00685 6d1e5b0987430e6b42a02423f317640a 268 Gene3D G3DSA:1.10.260.40 9 81 1.6E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS00685 6d1e5b0987430e6b42a02423f317640a 268 SUPERFAMILY SSF47413 4 72 1.74E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 DC74_RS00685 6d1e5b0987430e6b42a02423f317640a 268 PANTHER PTHR10245 2 76 6.9E-12 T 23-04-2016 DC74_RS00685 6d1e5b0987430e6b42a02423f317640a 268 SMART SM00530 12 67 5.5E-12 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DC74_RS00685 6d1e5b0987430e6b42a02423f317640a 268 Pfam PF13560 Helix-turn-helix domain 17 66 2.0E-11 T 23-04-2016 DC74_RS40675 8b3b22c3260feaf393affa140464f133 512 Pfam PF04213 Htaa 44 200 1.5E-42 T 23-04-2016 IPR007331 Htaa DC74_RS00950 799f7c9929e48b4d59422c368ee539bd 64 Gene3D G3DSA:3.40.50.1820 29 63 7.0E-6 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS00950 799f7c9929e48b4d59422c368ee539bd 64 SUPERFAMILY SSF53474 28 57 1.94E-5 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold DC74_RS15885 34c169e210271a283704c505ac471cfa 263 Pfam PF15698 Phosphatase 13 262 2.4E-111 T 23-04-2016 IPR031423 Uncharacterised phosphatase SCO2771 KEGG: 00051+3.1.3.-|KEGG: 00332+3.1.3.-|KEGG: 00565+3.1.3.-|KEGG: 00600+3.1.3.-|KEGG: 00730+3.1.3.-|KEGG: 00740+3.1.3.-|KEGG: 00760+3.1.3.- DC74_RS39240 afe33671322696978aa7ddce7ac8f14f 468 Pfam PF00328 Histidine phosphatase superfamily (branch 2) 79 197 4.1E-6 T 23-04-2016 IPR000560 Histidine phosphatase superfamily, clade-2 GO:0003993 DC74_RS39240 afe33671322696978aa7ddce7ac8f14f 468 Pfam PF00328 Histidine phosphatase superfamily (branch 2) 334 434 4.3E-5 T 23-04-2016 IPR000560 Histidine phosphatase superfamily, clade-2 GO:0003993 DC74_RS39240 afe33671322696978aa7ddce7ac8f14f 468 SUPERFAMILY SSF53254 49 214 1.01E-38 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS39240 afe33671322696978aa7ddce7ac8f14f 468 SUPERFAMILY SSF53254 241 463 1.01E-38 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS39240 afe33671322696978aa7ddce7ac8f14f 468 PANTHER PTHR20963 49 440 4.2E-26 T 23-04-2016 DC74_RS39240 afe33671322696978aa7ddce7ac8f14f 468 Gene3D G3DSA:3.40.50.1240 79 462 9.5E-35 T 23-04-2016 IPR029033 Histidine phosphatase superfamily DC74_RS29110 d74573b28deff2f692522f7b5f16ba9d 361 Pfam PF11268 Protein of unknown function (DUF3071) 12 179 3.5E-55 T 23-04-2016 IPR021421 Protein of unknown function DUF3071 DC74_RS15870 ea40be60af40f6590651eb781c829868 1644 Pfam PF15644 Papain fold toxin 1, glutamine deamidase 688 806 4.0E-27 T 23-04-2016 IPR028908 Tox-PL domain DC74_RS15870 ea40be60af40f6590651eb781c829868 1644 Pfam PF14440 Xanthomonas XOO_2897-like deaminase 1452 1551 5.2E-9 T 23-04-2016 IPR032722 Deaminase, Xanthomonas XOO_2897-like DC74_RS11610 05d63119bf0c8a6db197f5dedebdef41 227 Gene3D G3DSA:3.40.50.150 30 193 6.8E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS11610 05d63119bf0c8a6db197f5dedebdef41 227 SUPERFAMILY SSF53335 28 201 4.34E-33 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS11610 05d63119bf0c8a6db197f5dedebdef41 227 Pfam PF08241 Methyltransferase domain 42 137 2.2E-15 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 DC74_RS11610 05d63119bf0c8a6db197f5dedebdef41 227 PANTHER PTHR10108 30 210 5.7E-20 T 23-04-2016 DC74_RS22480 0707a6ba1432ba028c248cb2b7f25470 163 Pfam PF11377 Protein of unknown function (DUF3180) 9 149 4.6E-34 T 23-04-2016 IPR021517 Protein of unknown function DUF3180 DC74_RS35465 b0a0eed631967e7b2b1edad6169e4fbe 138 Pfam PF03771 Domain of unknown function (DUF317) 17 71 4.6E-9 T 23-04-2016 IPR005523 Domain of unknown function DUF317 DC74_RS02380 1160eb7479fea6388dd7b44f3436bd20 571 Pfam PF03169 OPT oligopeptide transporter protein 28 187 1.4E-9 T 23-04-2016 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 DC74_RS02380 1160eb7479fea6388dd7b44f3436bd20 571 Pfam PF03169 OPT oligopeptide transporter protein 199 564 1.8E-11 T 23-04-2016 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 DC74_RS31545 9e25eeb5007604182fac20e586c1da83 151 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 17 92 1.9E-6 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 DC74_RS31545 9e25eeb5007604182fac20e586c1da83 151 SUPERFAMILY SSF50475 14 134 4.09E-16 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS31545 9e25eeb5007604182fac20e586c1da83 151 Gene3D G3DSA:2.30.110.10 12 148 7.2E-35 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 DC74_RS12605 b48f38bd3baf14c638833287964a3c53 133 Pfam PF11239 Protein of unknown function (DUF3040) 1 81 4.7E-29 T 23-04-2016 IPR021401 Protein of unknown function DUF3040 DC74_RS24445 eb0940a6167d5fba8a5e080ce4074594 1085 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 686 1039 2.7E-56 T 23-04-2016 IPR011749 Conserved hypothetical protein CHP02243 DC74_RS18250 99c5d30fee307df5a0604d7ad775d49f 260 Pfam PF14016 Protein of unknown function (DUF4232) 124 242 2.0E-18 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS21600 c7ff914145d54c899005e88dfb670f34 261 Pfam PF09900 Predicted membrane protein (DUF2127) 75 220 1.5E-42 T 23-04-2016 IPR021125 Protein of unknown function DUF2127 DC74_RS07095 e217424cd685b5df051903274203c8d7 224 PANTHER PTHR10108 14 198 1.3E-18 T 23-04-2016 DC74_RS07095 e217424cd685b5df051903274203c8d7 224 SUPERFAMILY SSF53335 1 222 7.19E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS07095 e217424cd685b5df051903274203c8d7 224 Pfam PF13649 Methyltransferase domain 62 152 1.3E-18 T 23-04-2016 DC74_RS07095 e217424cd685b5df051903274203c8d7 224 Gene3D G3DSA:3.40.50.150 16 198 7.2E-34 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS20620 845c713be4427874ebad051826ddde74 240 ProDom PD190647 REGULATORY RESISTANCE TRANSCRIPTION TRANSCRIPTIONAL ANTIBIOTIC DNA-BINDING ACTIVATOR REGULATION ORF699 NOSIHEPTIDE 1 230 7.0E-36 T 23-04-2016 DC74_RS12575 c70f833c1f8847452c22c8a6625b0c41 123 Pfam PF04977 Septum formation initiator 45 108 5.0E-8 T 23-04-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 DC74_RS28855 3d6c240bbf25c061680270758333a222 239 SUPERFAMILY SSF53213 11 239 3.27E-7 T 23-04-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 DC74_RS16145 1be526e01e4e820ede0596ac2b9d0fe3 390 SUPERFAMILY SSF140959 51 372 6.08E-7 T 23-04-2016 DC74_RS25300 cf78aa2f5728e832ac986457c5b11350 693 Pfam PF13175 AAA ATPase domain 7 53 1.9E-12 T 23-04-2016 DC74_RS25300 cf78aa2f5728e832ac986457c5b11350 693 Pfam PF13175 AAA ATPase domain 195 402 9.1E-25 T 23-04-2016 DC74_RS25300 cf78aa2f5728e832ac986457c5b11350 693 SUPERFAMILY SSF52540 11 150 7.36E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25300 cf78aa2f5728e832ac986457c5b11350 693 SUPERFAMILY SSF52540 207 412 7.36E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25300 cf78aa2f5728e832ac986457c5b11350 693 Gene3D G3DSA:3.40.50.300 11 154 4.1E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25300 cf78aa2f5728e832ac986457c5b11350 693 Gene3D G3DSA:3.40.50.300 243 405 4.1E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS12450 4550673ed0eb73d3dadb44da8741bcdd 281 SUPERFAMILY SSF52833 87 254 1.2E-13 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS12450 4550673ed0eb73d3dadb44da8741bcdd 281 Gene3D G3DSA:3.40.30.10 90 280 1.2E-19 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS12450 4550673ed0eb73d3dadb44da8741bcdd 281 Pfam PF13462 Thioredoxin 88 260 4.2E-34 T 23-04-2016 IPR012336 Thioredoxin-like fold DC74_RS03540 bd1df7f392bff62cc893ccab32b4ac52 60 Gene3D G3DSA:2.40.50.140 2 51 2.5E-4 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold DC74_RS26225 84d366e888226b56140e8123f2ce8bea 379 Gene3D G3DSA:3.40.50.720 127 195 1.2E-6 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26225 84d366e888226b56140e8123f2ce8bea 379 Gene3D G3DSA:3.40.50.720 239 356 7.8E-5 T 23-04-2016 IPR016040 NAD(P)-binding domain DC74_RS26225 84d366e888226b56140e8123f2ce8bea 379 SUPERFAMILY SSF69572 128 356 1.83E-13 T 23-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 DC74_RS26225 84d366e888226b56140e8123f2ce8bea 379 Pfam PF00899 ThiF family 127 356 3.0E-13 T 23-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 DC74_RS20270 ac4676d3285c815841a8f92759ab3da4 156 Pfam PF07179 SseB protein N-terminal domain 78 144 7.0E-8 T 23-04-2016 IPR009839 SseB protein N-terminal domain DC74_RS22265 568ed2c2ad0491ea40b8f9afff5eb292 84 Pfam PF03777 Small secreted domain (DUF320) 31 83 3.5E-29 T 23-04-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species DC74_RS16020 e8e739295f5a3c29a9c9c48d86f967a2 489 SUPERFAMILY SSF48452 245 354 1.23E-6 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS16020 e8e739295f5a3c29a9c9c48d86f967a2 489 Gene3D G3DSA:1.25.40.10 380 449 2.1E-10 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS16020 e8e739295f5a3c29a9c9c48d86f967a2 489 Gene3D G3DSA:1.25.40.10 241 327 2.1E-10 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS40600 0c715a2a4228ccc66f11f3fc81230ada 172 Pfam PF13463 Winged helix DNA-binding domain 73 139 1.5E-5 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DC74_RS40600 0c715a2a4228ccc66f11f3fc81230ada 172 Gene3D G3DSA:1.10.10.10 57 145 3.4E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain DC74_RS01315 9246f6e8da9fc8d92dceea03d8d29f8a 79 Pfam PF05800 Gas vesicle synthesis protein GvpO 2 76 6.5E-32 T 23-04-2016 IPR008634 Gas vesicle protein GvpO GO:0031412 DC74_RS01315 9246f6e8da9fc8d92dceea03d8d29f8a 79 PIRSF PIRSF028743 1 78 4.8E-32 T 23-04-2016 IPR008634 Gas vesicle protein GvpO GO:0031412 DC74_RS26350 ac0eca959b65d5b22130bc689142b4a8 237 Pfam PF13398 Peptidase M50B-like 27 228 4.6E-60 T 23-04-2016 DC74_RS24800 8d1b802ace35bab895a54450448757d1 169 Pfam PF09349 OHCU decarboxylase 96 161 1.8E-8 T 23-04-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|UniPathway: UPA00394 DC74_RS24800 8d1b802ace35bab895a54450448757d1 169 Gene3D G3DSA:1.10.3330.10 94 165 3.2E-15 T 23-04-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|UniPathway: UPA00394 DC74_RS24800 8d1b802ace35bab895a54450448757d1 169 Gene3D G3DSA:1.10.3330.10 20 77 5.1E-10 T 23-04-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|UniPathway: UPA00394 DC74_RS24800 8d1b802ace35bab895a54450448757d1 169 SUPERFAMILY SSF158694 14 164 3.66E-25 T 23-04-2016 DC74_RS14140 333ca80f50bd9e24f51f103c7b9afdb3 328 Pfam PF11271 Protein of unknown function (DUF3068) 17 312 3.8E-66 T 23-04-2016 IPR021424 Protein of unknown function DUF3068 DC74_RS25005 f4cf248e9e8f7cb4f91b6cfdde5a9cb8 226 SUPERFAMILY SSF52540 3 119 2.05E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS25005 f4cf248e9e8f7cb4f91b6cfdde5a9cb8 226 PRINTS PR00988 Uridine kinase signature 142 152 8.9E-7 T 23-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 DC74_RS25005 f4cf248e9e8f7cb4f91b6cfdde5a9cb8 226 PRINTS PR00988 Uridine kinase signature 82 97 8.9E-7 T 23-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 DC74_RS25005 f4cf248e9e8f7cb4f91b6cfdde5a9cb8 226 PRINTS PR00988 Uridine kinase signature 11 28 8.9E-7 T 23-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 DC74_RS25005 f4cf248e9e8f7cb4f91b6cfdde5a9cb8 226 Gene3D G3DSA:3.40.50.300 13 159 2.0E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS05890 2ff59d9b3dcb95ee65f2eede79c68063 72 SUPERFAMILY SSF55469 3 69 6.15E-13 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS05890 2ff59d9b3dcb95ee65f2eede79c68063 72 Gene3D G3DSA:3.40.109.10 3 69 1.7E-11 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 DC74_RS07110 4ab966bba43dcedf1555d0f46c9feeb5 84 Pfam PF13490 Putative zinc-finger 3 39 1.1E-9 T 23-04-2016 IPR027383 Putative zinc-finger DC74_RS01575 5f5c936ab8a0953de959a4d5ac952850 224 Pfam PF03729 Short repeat of unknown function (DUF308) 95 165 3.9E-6 T 23-04-2016 IPR005325 Protein of unknown function DUF308, membrane DC74_RS01575 5f5c936ab8a0953de959a4d5ac952850 224 Pfam PF03729 Short repeat of unknown function (DUF308) 152 198 1.2E-7 T 23-04-2016 IPR005325 Protein of unknown function DUF308, membrane DC74_RS01575 5f5c936ab8a0953de959a4d5ac952850 224 Pfam PF03729 Short repeat of unknown function (DUF308) 39 108 1.3E-12 T 23-04-2016 IPR005325 Protein of unknown function DUF308, membrane DC74_RS08665 e346f0b2e201498f5a5f35426f8df76e 237 Gene3D G3DSA:3.10.490.10 19 207 2.2E-7 T 23-04-2016 IPR013024 Butirosin biosynthesis, BtrG-like DC74_RS34835 2eeee4945bc0de1a501338c248214024 125 Pfam PF13397 RNA polymerase-binding protein 4 107 3.4E-41 T 23-04-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 DC74_RS34835 2eeee4945bc0de1a501338c248214024 125 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 1 110 28.463 T 23-04-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 DC74_RS19000 b72eb757735cedc992e7527f88f7e269 215 Gene3D G3DSA:1.10.3630.10 6 213 1.7E-30 T 23-04-2016 DC74_RS19000 b72eb757735cedc992e7527f88f7e269 215 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 11 208 2.5E-39 T 23-04-2016 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 DC74_RS28075 0dab29302cafb08c78224df0a9e319ac 500 SUPERFAMILY SSF48452 244 462 8.54E-7 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS28075 0dab29302cafb08c78224df0a9e319ac 500 Gene3D G3DSA:1.25.40.10 263 451 8.7E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS04335 e1cc1d0ffc4253f68b040730183ed27c 168 Pfam PF06897 Protein of unknown function (DUF1269) 64 161 2.0E-24 T 23-04-2016 IPR009200 Protein of unknown function DUF1269, membrane associated DC74_RS12070 8eb0ed89620bfac40c20f5b8668f4ec4 294 Pfam PF13803 Domain of unknown function (DUF4184) 1 261 6.0E-46 T 23-04-2016 IPR025238 Protein of unknown function DUF4184 DC74_RS19965 64563b85dbb9c8e056fc78db9ade86cf 309 Pfam PF04893 Yip1 domain 144 301 2.6E-12 T 23-04-2016 IPR006977 Yip1 domain GO:0016020 DC74_RS19805 79fe3f2ae3e4e4b6a342789bd4daa250 266 Pfam PF09359 VTC domain 55 128 1.2E-5 T 23-04-2016 IPR018966 VTC domain DC74_RS18385 cf5f533290528a940d205f952393f70b 157 Pfam PF13581 Histidine kinase-like ATPase domain 12 124 5.2E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS00395 b3e4310cf2d7c77c46402abbe04713a6 170 Pfam PF13546 DDE superfamily endonuclease 8 155 9.4E-21 T 23-04-2016 DC74_RS34000 e1127f53d71550351c72d17471dc918e 263 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 255 7.7E-35 T 23-04-2016 IPR007404 LexA-binding, inner membrane-associated putative hydrolase DC74_RS12820 064b2934d6d120f29c1ddda5383a873c 438 Pfam PF05991 YacP-like NYN domain 317 436 6.0E-17 T 23-04-2016 IPR010298 Protein of unknown function DUF901 DC74_RS01300 7465c0eecd04f865d814e5e1a9a14add 83 Pfam PF05120 Gas vesicle protein G 8 76 5.0E-29 T 23-04-2016 IPR007804 Gas vesicle protein GvpG DC74_RS27955 8eca1a17489e3da8e136de1d85aaba2b 77 SUPERFAMILY SSF54909 2 75 2.41E-15 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS27955 8eca1a17489e3da8e136de1d85aaba2b 77 PANTHER PTHR30154 1 75 1.9E-15 T 23-04-2016 DC74_RS27955 8eca1a17489e3da8e136de1d85aaba2b 77 Gene3D G3DSA:3.30.70.920 4 75 2.0E-17 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS27955 8eca1a17489e3da8e136de1d85aaba2b 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 3.3E-13 T 23-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DC74_RS27955 8eca1a17489e3da8e136de1d85aaba2b 77 PANTHER PTHR30154:SF29 1 75 1.9E-15 T 23-04-2016 DC74_RS28250 cac5978ac0cc017d6092090323129475 283 PANTHER PTHR40761 3 251 4.5E-32 T 23-04-2016 DC74_RS28250 cac5978ac0cc017d6092090323129475 283 PANTHER PTHR40761:SF1 3 251 4.5E-32 T 23-04-2016 DC74_RS28250 cac5978ac0cc017d6092090323129475 283 SUPERFAMILY SSF103481 3 75 1.57E-5 T 23-04-2016 DC74_RS19680 ce6ed7ddf8114f7dc4f4d740371c6207 82 Pfam PF11273 Protein of unknown function (DUF3073) 2 62 1.2E-21 T 23-04-2016 IPR021426 Protein of unknown function DUF3073 DC74_RS15285 e6afb46a3e0ecbe130d0778405a6e139 116 Pfam PF14017 Protein of unknown function (DUF4233) 2 105 1.1E-32 T 23-04-2016 IPR025327 Protein of unknown function DUF4233 DC74_RS12415 6510b7e79cc72e3ed9726ff9653b55fa 218 Pfam PF10821 Protein of unknown function (DUF2567) 53 145 3.5E-7 T 23-04-2016 IPR021213 Protein of unknown function DUF2567 DC74_RS33685 365100440bef1dfc5514cb942c5c002e 179 Pfam PF09933 Predicted small integral membrane protein (DUF2165) 18 166 1.1E-51 T 23-04-2016 IPR018681 Protein of unknown function DUF2165, transmembrane DC74_RS14345 271854adbce35c1d2f39fcd95ff9d53d 316 Pfam PF05709 Phage tail protein 204 313 2.5E-7 T 23-04-2016 IPR008841 Siphovirus-type tail component DC74_RS17105 d5b2bca4a45e7b713a4f1c686b8e8a8e 301 Pfam PF11651 P22 coat protein - gene protein 5 19 234 2.6E-12 T 23-04-2016 IPR024659 Major capsid protein Gp5 DC74_RS17300 04fa687ca655da87ac4262ff4d7f7461 75 Pfam PF14117 Domain of unknown function (DUF4287) 9 67 8.8E-24 T 23-04-2016 IPR025629 Protein of unknown function DUF4287 DC74_RS16580 ad974be246ec5ac8b7eba14cc74c071e 74 Pfam PF11238 Protein of unknown function (DUF3039) 5 60 5.9E-32 T 23-04-2016 IPR021400 Protein of unknown function DUF3039 DC74_RS13300 bfb6aef6988c328a5cdb223c588ffb75 229 Pfam PF06197 Protein of unknown function (DUF998) 2 202 2.0E-27 T 23-04-2016 IPR009339 Protein of unknown function DUF998 DC74_RS16295 993323ca00a09fb7d58472bcf393a666 106 Pfam PF12277 Protein of unknown function (DUF3618) 4 49 7.4E-15 T 23-04-2016 IPR022062 Protein of unknown function DUF3618 DC74_RS07420 b67e80d3e135194d6e8d47a120d4db4e 146 Pfam PF03779 SPW repeat 37 84 1.2E-16 T 23-04-2016 IPR005530 SPW repeat DC74_RS07420 b67e80d3e135194d6e8d47a120d4db4e 146 Pfam PF03779 SPW repeat 92 138 2.6E-16 T 23-04-2016 IPR005530 SPW repeat DC74_RS04190 66247cf72f00ee4db48b53332e5fbd11 336 SUPERFAMILY SSF51445 11 111 3.89E-8 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS04190 66247cf72f00ee4db48b53332e5fbd11 336 SUPERFAMILY SSF51445 248 280 3.89E-8 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS04190 66247cf72f00ee4db48b53332e5fbd11 336 SUPERFAMILY SSF51445 142 216 3.89E-8 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily DC74_RS22940 8494b94a3fdc158790fbdc1a804a4491 332 Pfam PF01384 Phosphate transporter family 20 166 1.2E-39 T 23-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 DC74_RS22940 8494b94a3fdc158790fbdc1a804a4491 332 Pfam PF01384 Phosphate transporter family 165 320 3.8E-48 T 23-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 DC74_RS22940 8494b94a3fdc158790fbdc1a804a4491 332 PANTHER PTHR11101 6 332 1.7E-98 T 23-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 DC74_RS32365 898f1951fe2ee14e63761c38484e17e9 472 Pfam PF03559 NDP-hexose 2,3-dehydratase 46 248 7.9E-89 T 23-04-2016 IPR005212 NDP-hexose 2,3-dehydratase DC74_RS32365 898f1951fe2ee14e63761c38484e17e9 472 Pfam PF03559 NDP-hexose 2,3-dehydratase 262 465 6.3E-77 T 23-04-2016 IPR005212 NDP-hexose 2,3-dehydratase DC74_RS15250 39b366d956a261a53a5184a76f4d7995 148 Pfam PF13581 Histidine kinase-like ATPase domain 27 125 2.2E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS22160 33d8bf087bbb56f95469478313cb241c 144 Pfam PF13581 Histidine kinase-like ATPase domain 8 135 1.2E-30 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain DC74_RS22160 33d8bf087bbb56f95469478313cb241c 144 PANTHER PTHR35526:SF1 1 142 2.7E-28 T 23-04-2016 DC74_RS22160 33d8bf087bbb56f95469478313cb241c 144 PANTHER PTHR35526 1 142 2.7E-28 T 23-04-2016 DC74_RS14535 1e47160384ff52aded8b3cacab92db12 158 Pfam PF06114 Domain of unknown function (DUF955) 23 77 1.5E-4 T 23-04-2016 IPR010359 HTH domain, IrrE-type DC74_RS26080 9b1501bc1b2f85968941e81d1eb46ece 75 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 2.7E-28 T 23-04-2016 IPR021456 Protein of unknown function DUF3107 DC74_RS26650 6fa7abe11a07365f70233a2b3ba43f37 248 SUPERFAMILY SSF54909 124 206 5.16E-8 T 23-04-2016 IPR011008 Dimeric alpha-beta barrel DC74_RS26650 6fa7abe11a07365f70233a2b3ba43f37 248 Pfam PF03992 Antibiotic biosynthesis monooxygenase 135 191 9.4E-7 T 23-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain DC74_RS26650 6fa7abe11a07365f70233a2b3ba43f37 248 Gene3D G3DSA:3.30.70.900 15 115 3.0E-14 T 23-04-2016 DC74_RS26650 6fa7abe11a07365f70233a2b3ba43f37 248 Gene3D G3DSA:3.30.70.900 129 209 2.2E-15 T 23-04-2016 DC74_RS10515 2c0cf612058174907325b975c041dcc7 77 Pfam PF03777 Small secreted domain (DUF320) 21 76 5.3E-29 T 23-04-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species DC74_RS21220 d894dbb7f85013debbe324e3419206ac 534 Pfam PF06259 Alpha/beta hydrolase 310 475 1.0E-32 T 23-04-2016 IPR010427 Protein of unknown function DUF1023 DC74_RS25440 8074a1d95b1381f2bdbf7a29ed8a8166 223 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 15 61 1.7E-7 T 23-04-2016 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal DC74_RS21665 7d8edb7aea72c609945c22bcc7b66b8e 99 PIRSF PIRSF006909 1 99 4.3E-58 T 23-04-2016 IPR014447 Uncharacterised conserved protein UCP006909 DC74_RS08975 4d2277a757ba75df5bebc39f75372d2d 128 SUPERFAMILY SSF54593 12 121 9.26E-24 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS08975 4d2277a757ba75df5bebc39f75372d2d 128 Gene3D G3DSA:3.10.180.10 11 123 4.3E-25 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DC74_RS08975 4d2277a757ba75df5bebc39f75372d2d 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 113 5.6E-11 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DC74_RS13950 03d56686af5fd133b4dd68a472ee9f55 140 Pfam PF11253 Protein of unknown function (DUF3052) 15 139 1.0E-55 T 23-04-2016 IPR021412 Protein of unknown function DUF3052 DC74_RS06435 6ac51b9535b506e46fc5d47ba60604bd 204 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 5 186 1.6E-17 T 23-04-2016 IPR008628 Golgi phosphoprotein 3 GO:0048193|GO:0070273 DC74_RS19100 1e30fb31785ccc38756940ff71019e79 183 SUPERFAMILY SSF51338 16 63 1.65E-10 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS19100 1e30fb31785ccc38756940ff71019e79 183 Gene3D G3DSA:2.30.40.10 16 61 2.8E-5 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 DC74_RS27800 1222e5f7402a591defdaf7c779f9168a 77 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 16 75 8.1E-14 T 23-04-2016 IPR032716 Acyl-CoA carboxylase epsilon subunit DC74_RS24310 473abb11bfc55f62c3daf77f72e4a374 425 Gene3D G3DSA:2.60.40.10 318 417 1.1E-5 T 23-04-2016 IPR013783 Immunoglobulin-like fold DC74_RS16440 d17609b210a4b9f3edbee90fe0077c58 158 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 2.5E-35 T 23-04-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 DC74_RS10925 c434ba893fe34cfac21a70cd54f5eaa1 113 Pfam PF05331 Protein of unknown function (DUF742) 7 96 4.6E-24 T 23-04-2016 IPR007995 Protein of unknown function DUF742 DC74_RS10925 c434ba893fe34cfac21a70cd54f5eaa1 113 PANTHER PTHR36221 5 113 2.1E-19 T 23-04-2016 DC74_RS28245 61939ff707a56b61032b95133a29eb8a 415 Pfam PF09594 Protein of unknown function (DUF2029) 63 310 7.0E-14 T 23-04-2016 IPR018584 Glycosyltransferase family 87 GO:0016758 DC74_RS29830 b1946cdb58a0b618a069eb45dc3a7321 280 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 8 267 1.7E-31 T 23-04-2016 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain DC74_RS24270 830da241931f013630f5b480efc8cf09 120 ProDom PD034138 GP2 GENE GP5 18 83 2.0E-6 T 23-04-2016 IPR020289 Protein of unknown function Gp5 DC74_RS23740 a0c3d9876f4c1b1c3edca3d687c2227e 118 Pfam PF05331 Protein of unknown function (DUF742) 7 118 4.3E-36 T 23-04-2016 IPR007995 Protein of unknown function DUF742 DC74_RS23740 a0c3d9876f4c1b1c3edca3d687c2227e 118 PANTHER PTHR36221 5 118 1.9E-34 T 23-04-2016 DC74_RS02935 f084cd9f41e625e10efc3f19a4b9c428 227 Pfam PF14219 Domain of unknown function (DUF4328) 67 206 2.1E-26 T 23-04-2016 IPR025565 Domain of unknown function DUF4328 DC74_RS36135 54d62953f9feb5cf4b403ccb740cc791 116 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 3 85 1.5E-18 T 23-04-2016 IPR010152 CRISPR-associated protein Cas2 subtype DC74_RS36135 54d62953f9feb5cf4b403ccb740cc791 116 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 2 85 5.5E-32 T 23-04-2016 IPR010152 CRISPR-associated protein Cas2 subtype DC74_RS16040 96380857a683b8e23460111059bf8b75 446 SUPERFAMILY SSF52540 29 398 5.16E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS16040 96380857a683b8e23460111059bf8b75 446 Pfam PF13245 Part of AAA domain 25 90 5.9E-11 T 23-04-2016 DC74_RS16040 96380857a683b8e23460111059bf8b75 446 Gene3D G3DSA:3.40.50.300 16 230 3.0E-17 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS10765 1286379c81f69f6cae98f5ddc958e7d9 235 Pfam PF06912 Protein of unknown function (DUF1275) 13 219 1.8E-32 T 23-04-2016 IPR010699 Protein of unknown function DUF1275 DC74_RS10765 1286379c81f69f6cae98f5ddc958e7d9 235 PANTHER PTHR37314 11 235 6.1E-18 T 23-04-2016 DC74_RS11340 5be591779fcbf3e6d4e18f69629bbee2 120 Pfam PF11298 Protein of unknown function (DUF3099) 12 80 5.6E-22 T 23-04-2016 IPR021449 Protein of unknown function DUF3099 DC74_RS22630 5f8fe9c6b88120dd8d592d79f6c5f1f3 99 Pfam PF04149 Domain of unknown function (DUF397) 12 30 1.5E-7 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS22630 5f8fe9c6b88120dd8d592d79f6c5f1f3 99 Pfam PF04149 Domain of unknown function (DUF397) 38 92 1.2E-23 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS39675 2f4f2720e8a75c27e248bb7b6b3acb96 139 SUPERFAMILY SSF158745 30 123 3.01E-10 T 23-04-2016 DC74_RS39675 2f4f2720e8a75c27e248bb7b6b3acb96 139 Pfam PF05147 Lanthionine synthetase C-like protein 24 117 5.1E-8 T 23-04-2016 IPR007822 Lanthionine synthetase C-like DC74_RS38575 5f69959d15fbaad72e9d02c642e7587f 233 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 217 5.6E-29 T 23-04-2016 IPR007404 LexA-binding, inner membrane-associated putative hydrolase DC74_RS35620 8751021450e8ff0a9fdb0188436d4242 224 PANTHER PTHR33620 5 224 3.1E-37 T 23-04-2016 DC74_RS35620 8751021450e8ff0a9fdb0188436d4242 224 Pfam PF01730 UreF 34 173 2.2E-17 T 23-04-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 DC74_RS35620 8751021450e8ff0a9fdb0188436d4242 224 Hamap MF_01385 Urease accessory protein UreF [ureF]. 2 224 17.582 T 23-04-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 DC74_RS35620 8751021450e8ff0a9fdb0188436d4242 224 PIRSF PIRSF009467 1 224 3.1E-44 T 23-04-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 DC74_RS28060 3a69b1c797565051dc628b6816aae5d7 83 Gene3D G3DSA:2.10.230.10 15 69 5.2E-7 T 23-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 DC74_RS28060 3a69b1c797565051dc628b6816aae5d7 83 SUPERFAMILY SSF57938 16 64 6.54E-5 T 23-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 DC74_RS28985 757a71760672f8fbf02467161dcc138a 543 Pfam PF13830 Domain of unknown function (DUF4192) 129 471 1.2E-93 T 23-04-2016 IPR025447 Protein of unknown function DUF4192 DC74_RS37850 62555d161e4b7f877394740270c0386e 752 Pfam PF04632 Fusaric acid resistance protein family 417 728 1.0E-17 T 23-04-2016 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 DC74_RS37835 9663375196cff870daf6c3b1edd43cbe 335 Pfam PF07485 Domain of Unknown Function (DUF1259) 210 326 1.9E-34 T 23-04-2016 IPR011094 Uncharacterised protein family, LppY/LpqO DC74_RS37835 9663375196cff870daf6c3b1edd43cbe 335 Pfam PF07485 Domain of Unknown Function (DUF1259) 68 188 1.8E-34 T 23-04-2016 IPR011094 Uncharacterised protein family, LppY/LpqO DC74_RS11545 c53872d26b7c13a8f88ba94e61673853 323 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 282 316 8.0E-4 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain DC74_RS17470 4059c937baef10faa00432d175c82fc1 177 Pfam PF14431 YwqJ-like deaminase 41 166 1.4E-25 T 23-04-2016 IPR025968 YwqJ-like deaminase DC74_RS24220 91835b3e8aaea4ad9d4457d80e7250a8 197 ProDom PD022816 MAJOR GP23 GP20 CAPSID STRUCTURAL COAT TAIL GP19 DIRECT SEQUENCING 1 167 1.0E-21 T 23-04-2016 DC74_RS24815 b748a88e1d79dde949620a1f82a44e88 352 PRINTS PR01217 Proline rich extensin signature 255 271 2.9E-9 T 23-04-2016 DC74_RS24815 b748a88e1d79dde949620a1f82a44e88 352 PRINTS PR01217 Proline rich extensin signature 171 187 2.9E-9 T 23-04-2016 DC74_RS24815 b748a88e1d79dde949620a1f82a44e88 352 PRINTS PR01217 Proline rich extensin signature 195 207 2.9E-9 T 23-04-2016 DC74_RS24815 b748a88e1d79dde949620a1f82a44e88 352 PRINTS PR01217 Proline rich extensin signature 322 347 2.9E-9 T 23-04-2016 DC74_RS34315 a08a8e7978efbffc069a062ecdc08511 503 Pfam PF13515 Fusaric acid resistance protein-like 199 324 3.8E-17 T 23-04-2016 DC74_RS01570 2602825cd8f1e47be75a2a0787e82430 221 SUPERFAMILY SSF48150 45 203 5.23E-11 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS01570 2602825cd8f1e47be75a2a0787e82430 221 Gene3D G3DSA:1.10.340.30 48 151 3.8E-5 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 DC74_RS24895 d61f448deebc06512a25c2d8a35c568a 435 SUPERFAMILY SSF53756 96 294 2.98E-7 T 23-04-2016 DC74_RS09720 19fc66620938e0aec9d1e8c0b5dc0697 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 23 120 3.5E-38 T 23-04-2016 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 DC74_RS30180 1252101b93f6a491e2f701fc9c4f5b40 243 Pfam PF09348 Domain of unknown function (DUF1990) 36 194 2.2E-26 T 23-04-2016 IPR018960 Domain of unknown function DUF1990 DC74_RS30050 725c0ff1d63fd73136f5bced2e0f2089 610 Gene3D G3DSA:3.40.50.300 210 292 6.2E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30050 725c0ff1d63fd73136f5bced2e0f2089 610 Gene3D G3DSA:3.40.50.300 21 88 6.2E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS30050 725c0ff1d63fd73136f5bced2e0f2089 610 Gene3D G3DSA:3.40.50.300 396 415 6.2E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase DC74_RS24200 308737524f897708a9439ef78757fa5c 896 SUPERFAMILY SSF48371 451 688 3.07E-5 T 23-04-2016 IPR016024 Armadillo-type fold GO:0005488 DC74_RS07245 eccb8a3bbe8df54d1daebdb2a87dbc75 295 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 102 286 1.8E-38 T 23-04-2016 IPR018728 Domain of unknown function DUF2268 DC74_RS02350 27fb06358c16dfe7e6cea925ab864026 95 Pfam PF03777 Small secreted domain (DUF320) 24 78 8.9E-27 T 23-04-2016 IPR005528 Domain of unknown function DUF320, Streptomyces species DC74_RS29600 7e6de24498aa0ab5254315e8d783b6f9 286 SUPERFAMILY SSF56112 122 229 9.01E-5 T 23-04-2016 IPR011009 Protein kinase-like domain DC74_RS16430 5d48d74546b30367c6fab67ca47702fe 149 Pfam PF06271 RDD family 5 141 6.2E-25 T 23-04-2016 IPR010432 RDD DC74_RS02995 b21e256bda5e674e21e8c74ede5551ae 451 Gene3D G3DSA:1.25.40.10 214 414 2.4E-9 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 DC74_RS33160 5beb68945c40233bf067ab0087c5f069 195 Pfam PF03729 Short repeat of unknown function (DUF308) 81 149 2.0E-7 T 23-04-2016 IPR005325 Protein of unknown function DUF308, membrane DC74_RS33160 5beb68945c40233bf067ab0087c5f069 195 Pfam PF03729 Short repeat of unknown function (DUF308) 25 94 1.7E-10 T 23-04-2016 IPR005325 Protein of unknown function DUF308, membrane DC74_RS19425 6d59557d368cb2697132d11da7d94957 163 Pfam PF14016 Protein of unknown function (DUF4232) 28 154 6.0E-20 T 23-04-2016 IPR025326 Protein of unknown function DUF4232 DC74_RS32915 9cf6cb0f14acda57b9ac499350c03de1 172 PANTHER PTHR34473 8 171 4.0E-32 T 23-04-2016 DC74_RS32915 9cf6cb0f14acda57b9ac499350c03de1 172 Pfam PF03703 Bacterial PH domain 85 159 4.3E-16 T 23-04-2016 IPR005182 Domain of unknown function DUF304 DC74_RS19820 c2071ef308d7575aee0f9a1165555f62 338 SUPERFAMILY SSF111331 1 122 3.05E-8 T 23-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain DC74_RS31110 6ce2464de989badd639b70ed6b7213bd 323 Pfam PF13672 Protein phosphatase 2C 76 301 3.1E-8 T 23-04-2016 DC74_RS17090 16f909d8fb6cce9421252eec8e830de0 454 Pfam PF13148 Protein of unknown function (DUF3987) 123 316 1.9E-9 T 23-04-2016 IPR025048 Protein of unknown function DUF3987) DC74_RS01200 437fc95d69ab63c13d1462b4a7abb02c 171 PANTHER PTHR42305 1 171 7.2E-20 T 23-04-2016 DC74_RS18050 3c3403f37dbc7667f93d1a4912914537 99 PANTHER PTHR40040 18 99 8.0E-15 T 23-04-2016 DC74_RS38580 e5eae0b754422c2546d7c820fcef5186 374 Pfam PF06626 Protein of unknown function (DUF1152) 7 289 1.3E-75 T 23-04-2016 IPR010581 Protein of unknown function DUF1152 DC74_RS34795 7fce662111043da665e14443d1b4cf0e 384 SUPERFAMILY SSF159245 81 243 4.84E-8 T 23-04-2016 DC74_RS06480 ef4c36136f0e323ff5732e3170176b1f 273 SUPERFAMILY SSF55729 8 152 1.61E-7 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS06480 ef4c36136f0e323ff5732e3170176b1f 273 Gene3D G3DSA:3.40.630.30 18 152 1.4E-6 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase DC74_RS19260 a6b0632676b0291f38912281bea6d960 179 Pfam PF13396 Phospholipase_D-nuclease N-terminal 12 58 1.2E-10 T 23-04-2016 IPR027379 Cardiolipin synthase N-terminal DC74_RS28730 f1466153b4b9253c2d1ffdb5c6b9e03a 471 SUPERFAMILY SSF50998 100 382 1.8E-8 T 23-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DC74_RS35535 19b2a6e273db1b83aef60f1fe7c328fc 300 SUPERFAMILY SSF53335 127 156 1.49E-5 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS35535 19b2a6e273db1b83aef60f1fe7c328fc 300 SUPERFAMILY SSF53335 41 91 1.49E-5 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DC74_RS18000 28ba299a7c980950796bb0a8cb97313d 194 SUPERFAMILY SSF103473 48 167 4.45E-5 T 23-04-2016 IPR020846 Major facilitator superfamily domain DC74_RS24465 e35e7e50c5526f0c2e84997d2b772361 381 SUPERFAMILY SSF69279 33 199 2.66E-6 T 23-04-2016 DC74_RS25405 e1add446c59888c6eb39f69cc9387c3f 132 Pfam PF07811 TadE-like protein 15 57 3.3E-7 T 23-04-2016 IPR012495 TadE-like DC74_RS22135 8d468b566811c8bdf6753349ee9ad6ca 68 Pfam PF14029 Protein of unknown function (DUF4244) 15 65 5.3E-24 T 23-04-2016 IPR025338 Protein of unknown function DUF4244 DC74_RS14550 795310adc58957ed8cac1f650e0a0d14 331 Pfam PF07508 Recombinase 24 80 1.5E-5 T 23-04-2016 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 DC74_RS18015 28b0c5478412ed4f3bdf933f8249d8fd 350 Pfam PF14027 Protein of unknown function (DUF4243) 26 319 2.3E-29 T 23-04-2016 IPR025337 Domain of unknown function DUF4243 KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.-|UniPathway: UPA00287 DC74_RS21475 83c72812a6603e9a0e4121767ff822c6 308 Pfam PF10977 Protein of unknown function (DUF2797) 30 276 3.4E-22 T 23-04-2016 IPR021246 Protein of unknown function DUF2797 DC74_RS34465 399be80308178d11bc6a20d40fe05ccd 259 SUPERFAMILY SSF81324 154 258 4.32E-5 T 23-04-2016 DC74_RS30415 2a2b4c1ad1bbeb7713a8d02fdc683c51 267 Pfam PF03771 Domain of unknown function (DUF317) 58 114 6.0E-16 T 23-04-2016 IPR005523 Domain of unknown function DUF317 DC74_RS30415 2a2b4c1ad1bbeb7713a8d02fdc683c51 267 Pfam PF03771 Domain of unknown function (DUF317) 140 197 4.2E-17 T 23-04-2016 IPR005523 Domain of unknown function DUF317 DC74_RS17750 ff53146f1e2a7e6d91943d02a62a5220 65 Pfam PF04149 Domain of unknown function (DUF397) 7 62 9.0E-17 T 23-04-2016 IPR007278 Domain of unknown function DUF397 DC74_RS31260 1346dd48719dfe1e66e8e564b2db4c16 254 PRINTS PR01217 Proline rich extensin signature 40 56 1.3E-11 T 23-04-2016 DC74_RS31260 1346dd48719dfe1e66e8e564b2db4c16 254 PRINTS PR01217 Proline rich extensin signature 60 72 1.3E-11 T 23-04-2016 DC74_RS31260 1346dd48719dfe1e66e8e564b2db4c16 254 PRINTS PR01217 Proline rich extensin signature 72 93 1.3E-11 T 23-04-2016 DC74_RS31260 1346dd48719dfe1e66e8e564b2db4c16 254 PRINTS PR01217 Proline rich extensin signature 94 110 1.3E-11 T 23-04-2016 DC74_RS31260 1346dd48719dfe1e66e8e564b2db4c16 254 PRINTS PR01217 Proline rich extensin signature 112 129 1.3E-11 T 23-04-2016 DC74_RS17950 929a11be142eccd6fbea6da55fcc6782 163 Pfam PF04893 Yip1 domain 4 153 4.0E-8 T 23-04-2016 IPR006977 Yip1 domain GO:0016020 DC74_RS29150 432a8224f208e36c833aa9c7429fd53f 100 Pfam PF13834 Domain of unknown function (DUF4193) 1 99 5.5E-44 T 23-04-2016 IPR025242 Protein of unknown function DUF4193 DC74_RS05825 759f23dbf27cfe31f92f2aeb4a60ad6f 373 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 327 361 0.0012 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain DC74_RS13680 16a338e78dbae48411127a5c7032c7e8 423 Pfam PF02361 Cobalt transport protein 72 233 2.1E-6 T 23-04-2016 IPR003339 ABC/ECF transporter, transmembrane component DC74_RS19170 8ac2618de10d83658091a16e6216cd2f 157 Gene3D G3DSA:1.10.287.1060 56 137 6.5E-4 T 23-04-2016 DC74_RS18095 8f5722942c3c60a22ac76e2a122faf65 483 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 78 212 7.9E-11 T 23-04-2016 DC74_RS13485 a44702d3065e718c545a852a8856eb9a 237 Pfam PF11651 P22 coat protein - gene protein 5 1 205 1.0E-18 T 23-04-2016 IPR024659 Major capsid protein Gp5 DC74_RS01250 73642f2c83defeabdcb2e46e4649d918 132 PANTHER PTHR36974 1 130 2.6E-30 T 23-04-2016 DC74_RS02710 3ab8cbe552e9f3900fe40a59aa6b14f8 185 Pfam PF11695 Domain of unknown function (DUF3291) 4 163 4.9E-39 T 23-04-2016 IPR021708 Domain of unknown function DUF3291 DC74_RS16785 96abfb86cf24a412685b397ba74888db 157 Pfam PF04138 GtrA-like protein 15 124 4.1E-17 T 23-04-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021