locus-tag	class	description
SAZ_RS00060	COG0419	ATPase involved in DNA repair
SAZ_RS00065	COG0420	3'-5' exonuclease activity
SAZ_RS00115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS00120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS00125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS00140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS00150	COG1181	Belongs to the D-alanine--D-alanine ligase family
SAZ_RS00350	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SAZ_RS00450	COG3328	transposase activity
SAZ_RS00480	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SAZ_RS00485	COG4977	sequence-specific DNA binding
SAZ_RS00555	COG1278	Cold shock
SAZ_RS00710	COG0662	Cupin 2, conserved barrel domain protein
SAZ_RS00750	COG3293	Transposase
SAZ_RS00805	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS00855	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SAZ_RS00890	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SAZ_RS00945	COG0346	lactoylglutathione lyase activity
SAZ_RS00950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SAZ_RS00960	COG0798	PFAM Bile acid sodium symporter
SAZ_RS00965	COG0789	Transcriptional regulator
SAZ_RS00975	COG2205	protein histidine kinase activity
SAZ_RS00980	COG0745	RESPONSE REGULATOR receiver
SAZ_RS00995	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAZ_RS00995	COG2755	lipolytic protein G-D-S-L family
SAZ_RS01005	COG0154	amidase activity
SAZ_RS01010	COG1609	Transcriptional regulator
SAZ_RS01050	COG0384	phenazine biosynthesis protein PhzF
SAZ_RS01065	COG1733	regulation of RNA biosynthetic process
SAZ_RS01070	COG0596	Alpha beta hydrolase
SAZ_RS01075	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS01085	COG0583	DNA-binding transcription factor activity
SAZ_RS01105	COG0019	diaminopimelate decarboxylase activity
SAZ_RS01120	COG0531	amino acid
SAZ_RS01125	COG2197	response regulator
SAZ_RS01130	COG4585	Histidine kinase
SAZ_RS01155	COG0285	dihydrofolate synthase activity
SAZ_RS01195	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS01205	COG3483	tryptophan 2,3-dioxygenase activity
SAZ_RS01215	COG2192	nodulation
SAZ_RS01220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SAZ_RS01225	COG2226	methyltransferase
SAZ_RS01255	COG4221	oxidoreductase activity
SAZ_RS01260	COG4221	oxidoreductase activity
SAZ_RS01330	COG2205	protein histidine kinase activity
SAZ_RS01335	COG0745	RESPONSE REGULATOR receiver
SAZ_RS01350	COG2267	carboxylic ester hydrolase activity
SAZ_RS01355	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SAZ_RS01370	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS01390	COG0154	amidase activity
SAZ_RS01395	COG1309	transcriptional regulator
SAZ_RS01400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SAZ_RS01405	COG1733	regulation of RNA biosynthetic process
SAZ_RS01410	COG3321	synthase
SAZ_RS01410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS01410	COG0604	alcohol dehydrogenase
SAZ_RS01410	COG4221	oxidoreductase activity
SAZ_RS01450	COG3335	DDE superfamily endonuclease
SAZ_RS01475	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SAZ_RS01505	COG1309	transcriptional regulator
SAZ_RS01535	COG1620	l-lactate permease
SAZ_RS01545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SAZ_RS01550	COG0277	FAD linked oxidase domain protein
SAZ_RS01550	COG0247	lactate metabolic process
SAZ_RS01580	COG3290	protein histidine kinase activity
SAZ_RS01585	COG1309	transcriptional regulator
SAZ_RS01600	COG2226	methyltransferase
SAZ_RS01665	COG0517	IMP dehydrogenase activity
SAZ_RS01665	COG0516	GMP reductase activity
SAZ_RS01670	COG0517	IMP dehydrogenase activity
SAZ_RS01670	COG0516	GMP reductase activity
SAZ_RS01675	COG0517	IMP dehydrogenase activity
SAZ_RS01675	COG0516	GMP reductase activity
SAZ_RS01680	COG2326	polyphosphate kinase activity
SAZ_RS01685	COG0745	RESPONSE REGULATOR receiver
SAZ_RS01690	COG2205	protein histidine kinase activity
SAZ_RS01835	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SAZ_RS01870	COG2814	Major facilitator Superfamily
SAZ_RS01895	COG1595	DNA-templated transcription, initiation
SAZ_RS01965	COG0583	DNA-binding transcription factor activity
SAZ_RS01970	COG2814	Major facilitator Superfamily
SAZ_RS01985	COG4585	Histidine kinase
SAZ_RS01990	COG2197	response regulator
SAZ_RS01995	COG1051	belongs to the nudix hydrolase family
SAZ_RS02020	COG1846	Transcriptional regulator
SAZ_RS02070	COG3903	Transcriptional regulator
SAZ_RS02070	COG3629	intracellular signal transduction
SAZ_RS02120	COG4585	Histidine kinase
SAZ_RS02135	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SAZ_RS02155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS02175	COG0494	nUDIX hydrolase
SAZ_RS02265	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SAZ_RS02270	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SAZ_RS02275	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SAZ_RS02315	COG0515	serine threonine protein kinase
SAZ_RS02315	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SAZ_RS02350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS02415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SAZ_RS02435	COG0477	Major facilitator Superfamily
SAZ_RS02445	COG4941	Belongs to the sigma-70 factor family
SAZ_RS02455	COG1064	alcohol dehydrogenase
SAZ_RS02475	COG1611	Belongs to the LOG family
SAZ_RS02525	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SAZ_RS02550	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS02555	COG0477	Major facilitator Superfamily
SAZ_RS02560	COG1819	glycosyl
SAZ_RS02565	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SAZ_RS02575	COG0328	RNA-DNA hybrid ribonuclease activity
SAZ_RS02580	COG0477	Major facilitator Superfamily
SAZ_RS02585	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SAZ_RS02590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAZ_RS02610	COG4977	sequence-specific DNA binding
SAZ_RS02620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS02645	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SAZ_RS02745	COG1181	Belongs to the D-alanine--D-alanine ligase family
SAZ_RS02800	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SAZ_RS02810	COG3485	protocatechuate 3,4-dioxygenase
SAZ_RS02840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SAZ_RS02845	COG3340	Belongs to the peptidase S51 family
SAZ_RS02895	COG4585	Histidine kinase
SAZ_RS02900	COG2197	response regulator
SAZ_RS02915	COG1090	epimerase
SAZ_RS02925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SAZ_RS02950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SAZ_RS02965	COG4948	Mandelate Racemase Muconate Lactonizing
SAZ_RS02970	COG0179	Fumarylacetoacetate (FAA) hydrolase
SAZ_RS02980	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SAZ_RS02985	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SAZ_RS02990	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SAZ_RS03000	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS03015	COG2197	response regulator
SAZ_RS03020	COG1942	4-Oxalocrotonate Tautomerase
SAZ_RS03050	COG0590	tRNA wobble adenosine to inosine editing
SAZ_RS03065	COG0583	DNA-binding transcription factor activity
SAZ_RS03095	COG0488	(ABC) transporter
SAZ_RS03100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS03105	COG2318	DinB family
SAZ_RS03110	COG0326	Molecular chaperone. Has ATPase activity
SAZ_RS03155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAZ_RS03160	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SAZ_RS03165	COG1473	amidohydrolase
SAZ_RS03170	COG0477	Major facilitator Superfamily
SAZ_RS03180	COG2124	cytochrome p450
SAZ_RS03185	COG0596	Alpha beta hydrolase
SAZ_RS03210	COG1414	Transcriptional regulator
SAZ_RS03215	COG1461	Dihydroxyacetone kinase
SAZ_RS03220	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SAZ_RS03240	COG0697	spore germination
SAZ_RS03255	COG1254	Belongs to the acylphosphatase family
SAZ_RS03285	COG2197	response regulator
SAZ_RS03300	COG3340	Belongs to the peptidase S51 family
SAZ_RS03320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAZ_RS03340	COG2267	carboxylic ester hydrolase activity
SAZ_RS03345	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS03355	COG2814	Major facilitator Superfamily
SAZ_RS03375	COG3848	Pyruvate phosphate dikinase
SAZ_RS03375	COG0574	Belongs to the PEP-utilizing enzyme family
SAZ_RS03445	COG0640	Transcriptional regulator
SAZ_RS03455	COG1695	Transcriptional regulator
SAZ_RS03515	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS03520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SAZ_RS03525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAZ_RS03530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAZ_RS03535	COG1335	isochorismatase
SAZ_RS03560	COG5006	permease, DMT superfamily
SAZ_RS03565	COG0583	DNA-binding transcription factor activity
SAZ_RS03575	COG0738	Major facilitator superfamily
SAZ_RS03590	COG0583	DNA-binding transcription factor activity
SAZ_RS03595	COG0473	3-isopropylmalate dehydrogenase activity
SAZ_RS03620	COG3321	synthase
SAZ_RS03620	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS03620	COG0604	alcohol dehydrogenase
SAZ_RS03690	COG1595	DNA-templated transcription, initiation
SAZ_RS03705	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS03715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SAZ_RS03725	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS03735	COG0531	amino acid
SAZ_RS03810	COG2345	Transcriptional regulator
SAZ_RS03815	COG0702	epimerase
SAZ_RS03820	COG3631	Ketosteroid isomerase-related protein
SAZ_RS03845	COG0702	epimerase
SAZ_RS03890	COG0644	oxidoreductase
SAZ_RS03895	COG3655	Transcriptional regulator
SAZ_RS03945	COG2124	cytochrome p450
SAZ_RS03955	COG4977	sequence-specific DNA binding
SAZ_RS03965	COG3335	DDE superfamily endonuclease
SAZ_RS03970	COG3335	DDE superfamily endonuclease
SAZ_RS03985	COG3033	Beta-eliminating lyase
SAZ_RS03995	COG0513	Belongs to the DEAD box helicase family
SAZ_RS04025	COG0741	lytic transglycosylase activity
SAZ_RS04025	COG1196	nuclear chromosome segregation
SAZ_RS04025	COG0739	heme binding
SAZ_RS04065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SAZ_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS04130	COG0477	Major facilitator Superfamily
SAZ_RS04135	COG2226	methyltransferase
SAZ_RS04140	COG0488	(ABC) transporter
SAZ_RS04165	COG1309	transcriptional regulator
SAZ_RS04175	COG2272	Belongs to the type-B carboxylesterase lipase family
SAZ_RS04180	COG3226	Transcriptional regulator
SAZ_RS04200	COG2208	phosphoserine phosphatase activity
SAZ_RS04200	COG2770	Histidine kinase
SAZ_RS04220	COG1366	Belongs to the anti-sigma-factor antagonist family
SAZ_RS04225	COG1191	sigma factor activity
SAZ_RS04230	COG1819	glycosyl
SAZ_RS04295	COG0701	Predicted permease
SAZ_RS04300	COG0745	RESPONSE REGULATOR receiver
SAZ_RS04305	COG2205	protein histidine kinase activity
SAZ_RS04320	COG1959	2 iron, 2 sulfur cluster binding
SAZ_RS04340	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS04345	COG0583	DNA-binding transcription factor activity
SAZ_RS04365	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SAZ_RS04395	COG1595	DNA-templated transcription, initiation
SAZ_RS04400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAZ_RS04410	COG2080	2 iron, 2 sulfur cluster binding
SAZ_RS04415	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SAZ_RS04425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SAZ_RS04455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAZ_RS04465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SAZ_RS04470	COG2124	cytochrome p450
SAZ_RS04505	COG3387	PFAM Glycoside hydrolase 15-related
SAZ_RS04515	COG0667	Aldo Keto reductase
SAZ_RS04525	COG2226	methyltransferase
SAZ_RS04540	COG2226	methyltransferase
SAZ_RS04560	COG4221	oxidoreductase activity
SAZ_RS04580	COG2318	DinB family
SAZ_RS04605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SAZ_RS04625	COG2226	methyltransferase
SAZ_RS04630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SAZ_RS04635	COG1993	acr, cog1993
SAZ_RS04640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SAZ_RS04650	COG0531	amino acid
SAZ_RS04665	COG1309	transcriptional regulator
SAZ_RS04675	COG2084	Dehydrogenase
SAZ_RS04680	COG2197	response regulator
SAZ_RS04695	COG1115	amino acid carrier protein
SAZ_RS04700	COG0745	RESPONSE REGULATOR receiver
SAZ_RS04740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAZ_RS04765	COG0745	RESPONSE REGULATOR receiver
SAZ_RS04780	COG2239	Acts as a magnesium transporter
SAZ_RS04820	COG0181	hydroxymethylbilane synthase activity
SAZ_RS04855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAZ_RS04865	COG1794	racemase activity, acting on amino acids and derivatives
SAZ_RS04910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAZ_RS04930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS04945	COG2124	cytochrome p450
SAZ_RS04995	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS05000	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS05010	COG2409	Drug exporters of the RND superfamily
SAZ_RS05030	COG1271	oxidase subunit
SAZ_RS05035	COG1294	oxidase, subunit
SAZ_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS05065	COG0577	efflux transmembrane transporter activity
SAZ_RS05070	COG0577	efflux transmembrane transporter activity
SAZ_RS05070	COG1136	(ABC) transporter
SAZ_RS05150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SAZ_RS05170	COG0604	alcohol dehydrogenase
SAZ_RS05190	COG0492	ferredoxin-NADP+ reductase activity
SAZ_RS05210	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS05225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SAZ_RS05240	COG2124	cytochrome p450
SAZ_RS05245	COG0604	alcohol dehydrogenase
SAZ_RS05250	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAZ_RS05255	COG1819	glycosyl
SAZ_RS05260	COG0789	Transcriptional regulator
SAZ_RS05265	COG1802	Transcriptional regulator
SAZ_RS05270	COG0596	Alpha beta hydrolase
SAZ_RS05275	COG1309	transcriptional regulator
SAZ_RS05280	COG2272	Belongs to the type-B carboxylesterase lipase family
SAZ_RS05295	COG3387	PFAM Glycoside hydrolase 15-related
SAZ_RS05325	COG1902	pentaerythritol trinitrate reductase activity
SAZ_RS05335	COG1335	isochorismatase
SAZ_RS05345	COG0583	DNA-binding transcription factor activity
SAZ_RS05350	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS05395	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SAZ_RS05400	COG4988	ABC transporter
SAZ_RS05410	COG1271	oxidase subunit
SAZ_RS05415	COG0783	Belongs to the Dps family
SAZ_RS05420	COG2814	Major facilitator Superfamily
SAZ_RS05425	COG3619	membrane
SAZ_RS05430	COG2259	Doxx family
SAZ_RS05435	COG1335	isochorismatase
SAZ_RS05445	COG0300	oxidoreductase activity
SAZ_RS05450	COG4221	oxidoreductase activity
SAZ_RS05480	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SAZ_RS05505	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SAZ_RS05535	COG0367	asparagine synthase
SAZ_RS05540	COG2814	Major facilitator Superfamily
SAZ_RS05545	COG2608	mercury ion transmembrane transporter activity
SAZ_RS05550	COG1120	ATPase activity
SAZ_RS05555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAZ_RS05585	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS05590	COG1595	DNA-templated transcription, initiation
SAZ_RS05650	COG4968	Prepilin-type N-terminal cleavage methylation domain
SAZ_RS05655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SAZ_RS05660	COG1459	type II secretion system
SAZ_RS05685	COG0202	RNA polymerase activity
SAZ_RS05690	COG0202	RNA polymerase activity
SAZ_RS05710	COG1124	(ABC) transporter
SAZ_RS05715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAZ_RS05720	COG0601	transmembrane transport
SAZ_RS05725	COG4166	transmembrane transport
SAZ_RS05740	COG4948	Mandelate Racemase Muconate Lactonizing
SAZ_RS05745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SAZ_RS05765	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SAZ_RS05785	COG2132	Multicopper oxidase
SAZ_RS05810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SAZ_RS05835	COG0477	Major facilitator Superfamily
SAZ_RS05840	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS05845	COG1024	Enoyl-CoA hydratase
SAZ_RS05850	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS05860	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS05865	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS05875	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS05885	COG2186	Transcriptional regulator
SAZ_RS05915	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SAZ_RS05970	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SAZ_RS05985	COG4310	Domain of unknown function (DUF2172)
SAZ_RS05995	COG1215	transferase activity, transferring glycosyl groups
SAZ_RS06010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SAZ_RS06055	COG1937	Protein conserved in bacteria
SAZ_RS06070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAZ_RS06145	COG0300	oxidoreductase activity
SAZ_RS06150	COG1309	transcriptional regulator
SAZ_RS06165	COG0069	glutamate synthase activity
SAZ_RS06180	COG3903	Transcriptional regulator
SAZ_RS06180	COG3629	intracellular signal transduction
SAZ_RS06185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS06190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS06190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS06195	COG3251	PFAM MbtH domain protein
SAZ_RS06200	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SAZ_RS06205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS06230	COG2208	phosphoserine phosphatase activity
SAZ_RS06235	COG2172	sigma factor antagonist activity
SAZ_RS06240	COG2172	sigma factor antagonist activity
SAZ_RS06245	COG1366	Belongs to the anti-sigma-factor antagonist family
SAZ_RS06250	COG1366	Belongs to the anti-sigma-factor antagonist family
SAZ_RS06275	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SAZ_RS06295	COG2814	Major facilitator Superfamily
SAZ_RS06300	COG0604	alcohol dehydrogenase
SAZ_RS06315	COG3973	AAA domain
SAZ_RS06350	COG2986	histidine ammonia-lyase
SAZ_RS06355	COG0477	Major facilitator Superfamily
SAZ_RS06375	COG0789	Transcriptional regulator
SAZ_RS06380	COG0667	Aldo Keto reductase
SAZ_RS06400	COG2205	protein histidine kinase activity
SAZ_RS06405	COG0745	RESPONSE REGULATOR receiver
SAZ_RS06410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SAZ_RS06410	COG1017	nitric oxide dioxygenase activity
SAZ_RS06425	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SAZ_RS06480	COG3321	synthase
SAZ_RS06480	COG4221	oxidoreductase activity
SAZ_RS06480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS06480	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS06490	COG3251	PFAM MbtH domain protein
SAZ_RS06495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SAZ_RS06530	COG2135	peptidase activity
SAZ_RS06540	COG2205	protein histidine kinase activity
SAZ_RS06545	COG0745	RESPONSE REGULATOR receiver
SAZ_RS06550	COG0577	efflux transmembrane transporter activity
SAZ_RS06555	COG1136	(ABC) transporter
SAZ_RS06580	COG1309	transcriptional regulator
SAZ_RS06605	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAZ_RS06610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAZ_RS06630	COG0402	S-adenosylhomocysteine deaminase activity
SAZ_RS06645	COG0789	Transcriptional regulator
SAZ_RS06670	COG1309	transcriptional regulator
SAZ_RS06675	COG0659	secondary active sulfate transmembrane transporter activity
SAZ_RS06685	COG0583	DNA-binding transcription factor activity
SAZ_RS06695	COG0515	serine threonine protein kinase
SAZ_RS06695	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SAZ_RS06700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SAZ_RS06700	COG0515	serine threonine protein kinase
SAZ_RS06710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SAZ_RS06735	COG1113	amino acid transport
SAZ_RS06740	COG3224	Antibiotic biosynthesis monooxygenase
SAZ_RS06760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAZ_RS06765	COG0477	Major facilitator Superfamily
SAZ_RS06775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAZ_RS06790	COG0456	acetyltransferase
SAZ_RS06790	COG1846	Transcriptional regulator
SAZ_RS06800	COG0513	Belongs to the DEAD box helicase family
SAZ_RS06805	COG1278	Cold shock
SAZ_RS06845	COG3979	chitinase
SAZ_RS06875	COG1472	Belongs to the glycosyl hydrolase 3 family
SAZ_RS06880	COG2124	cytochrome p450
SAZ_RS06905	COG3387	PFAM Glycoside hydrolase 15-related
SAZ_RS06935	COG0300	oxidoreductase activity
SAZ_RS06940	COG0189	ligase activity
SAZ_RS06960	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS06975	COG2124	cytochrome p450
SAZ_RS06990	COG0542	response to heat
SAZ_RS07060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SAZ_RS07070	COG3290	protein histidine kinase activity
SAZ_RS07075	COG4565	transcriptional regulatory protein
SAZ_RS07090	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SAZ_RS07115	COG0583	DNA-binding transcription factor activity
SAZ_RS07125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SAZ_RS07130	COG0076	glutamate decarboxylase activity
SAZ_RS07160	COG2186	Transcriptional regulator
SAZ_RS07165	COG1027	Aspartate ammonia-lyase
SAZ_RS07175	COG0640	Transcriptional regulator
SAZ_RS07220	COG0529	Catalyzes the synthesis of activated sulfate
SAZ_RS07230	COG0583	DNA-binding transcription factor activity
SAZ_RS07300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SAZ_RS07315	COG0604	alcohol dehydrogenase
SAZ_RS07315	COG3321	synthase
SAZ_RS07320	COG2365	Tyrosine phosphatase family
SAZ_RS07325	COG3321	synthase
SAZ_RS07325	COG0604	alcohol dehydrogenase
SAZ_RS07330	COG3321	synthase
SAZ_RS07330	COG0604	alcohol dehydrogenase
SAZ_RS07330	COG0604	alcohol dehydrogenase
SAZ_RS07330	COG3321	synthase
SAZ_RS07345	COG3321	synthase
SAZ_RS07345	COG0604	alcohol dehydrogenase
SAZ_RS07420	COG2197	response regulator
SAZ_RS07425	COG4585	Histidine kinase
SAZ_RS07435	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SAZ_RS07445	COG0494	nUDIX hydrolase
SAZ_RS07465	COG0531	amino acid
SAZ_RS07475	COG0772	Belongs to the SEDS family
SAZ_RS07505	COG0076	glutamate decarboxylase activity
SAZ_RS07525	COG2124	cytochrome p450
SAZ_RS07545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SAZ_RS07565	COG1309	transcriptional regulator
SAZ_RS07580	COG2309	aminopeptidase activity
SAZ_RS07590	COG0477	Major facilitator Superfamily
SAZ_RS07615	COG1335	isochorismatase
SAZ_RS07620	COG0596	Alpha beta hydrolase
SAZ_RS07640	COG1653	transport
SAZ_RS07690	COG2274	protein secretion by the type I secretion system
SAZ_RS07705	COG1796	DNA polymerase
SAZ_RS07705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SAZ_RS07710	COG0583	DNA-binding transcription factor activity
SAZ_RS07715	COG0156	8-amino-7-oxononanoate synthase activity
SAZ_RS07720	COG1063	alcohol dehydrogenase
SAZ_RS07745	COG2318	DinB family
SAZ_RS07775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SAZ_RS07780	COG5504	Zn-dependent protease
SAZ_RS07800	COG0745	RESPONSE REGULATOR receiver
SAZ_RS07805	COG1024	Enoyl-CoA hydratase
SAZ_RS07805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SAZ_RS07820	COG0477	Major facilitator Superfamily
SAZ_RS07855	COG3585	molybdate ion transport
SAZ_RS07870	COG2080	2 iron, 2 sulfur cluster binding
SAZ_RS07870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SAZ_RS07875	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SAZ_RS07880	COG3835	regulator
SAZ_RS07945	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SAZ_RS07970	COG0438	transferase activity, transferring glycosyl groups
SAZ_RS08005	COG2226	methyltransferase
SAZ_RS08020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAZ_RS08025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAZ_RS08050	COG0386	Belongs to the glutathione peroxidase family
SAZ_RS08060	COG1132	(ABC) transporter
SAZ_RS08065	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SAZ_RS08090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SAZ_RS08095	COG0667	Aldo Keto reductase
SAZ_RS08125	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS08140	COG4585	Histidine kinase
SAZ_RS08165	COG0596	Alpha beta hydrolase
SAZ_RS08175	COG1733	regulation of RNA biosynthetic process
SAZ_RS08185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAZ_RS08220	COG0740	serine-type endopeptidase activity
SAZ_RS08225	COG0740	serine-type endopeptidase activity
SAZ_RS08235	COG0740	serine-type endopeptidase activity
SAZ_RS08255	COG2186	Transcriptional regulator
SAZ_RS08265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SAZ_RS08295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SAZ_RS08310	COG0483	inositol monophosphate 1-phosphatase activity
SAZ_RS08425	COG0477	Major facilitator Superfamily
SAZ_RS08435	COG2186	Transcriptional regulator
SAZ_RS08450	COG0778	Nitroreductase
SAZ_RS08460	COG4106	trans-aconitate 2-methyltransferase activity
SAZ_RS08470	COG2197	response regulator
SAZ_RS08500	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS08505	COG0825	malonyl-CoA metabolic process
SAZ_RS08505	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SAZ_RS08515	COG0697	spore germination
SAZ_RS08535	COG0492	ferredoxin-NADP+ reductase activity
SAZ_RS08615	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SAZ_RS08615	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SAZ_RS08625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SAZ_RS08645	COG1716	ATPase activity
SAZ_RS08670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SAZ_RS08710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SAZ_RS08720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAZ_RS08730	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SAZ_RS08735	COG1177	transmembrane transport
SAZ_RS08740	COG1176	ABC-type spermidine putrescine transport system, permease component I
SAZ_RS08745	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SAZ_RS08750	COG3842	ATPase activity
SAZ_RS08760	COG4977	sequence-specific DNA binding
SAZ_RS08775	COG0596	Alpha beta hydrolase
SAZ_RS08800	COG2146	nitrite reductase [NAD(P)H] activity
SAZ_RS08825	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SAZ_RS08845	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SAZ_RS08850	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SAZ_RS08855	COG1984	allophanate hydrolase subunit 2
SAZ_RS08870	COG0438	transferase activity, transferring glycosyl groups
SAZ_RS08915	COG0259	pyridoxamine-phosphate oxidase activity
SAZ_RS08940	COG1024	Enoyl-CoA hydratase
SAZ_RS08950	COG1605	Chorismate mutase
SAZ_RS08980	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS09000	COG2070	2-Nitropropane dioxygenase
SAZ_RS09020	COG0515	serine threonine protein kinase
SAZ_RS09030	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS09050	COG2226	methyltransferase
SAZ_RS09060	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SAZ_RS09065	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SAZ_RS09080	COG0456	acetyltransferase
SAZ_RS09090	COG0587	DNA-directed DNA polymerase activity
SAZ_RS09105	COG0596	Alpha beta hydrolase
SAZ_RS09120	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SAZ_RS09125	COG2188	Transcriptional regulator
SAZ_RS09130	COG0477	Major facilitator Superfamily
SAZ_RS09145	COG2233	PERMEase
SAZ_RS09160	COG1278	Cold shock
SAZ_RS09165	COG2376	Dihydroxyacetone kinase
SAZ_RS09170	COG1461	Dihydroxyacetone kinase
SAZ_RS09200	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS09240	COG0395	ABC-type sugar transport system, permease component
SAZ_RS09250	COG1793	dna ligase
SAZ_RS09260	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SAZ_RS09300	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS09320	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SAZ_RS09325	COG0463	Glycosyl transferase, family 2
SAZ_RS09340	COG3217	Mosc domain protein beta barrel domain protein
SAZ_RS09340	COG0633	Ferredoxin
SAZ_RS09360	COG0464	growth
SAZ_RS09370	COG1349	DNA-binding transcription factor activity
SAZ_RS09430	COG1940	carbohydrate kinase activity
SAZ_RS09435	COG2223	nitrite transmembrane transporter activity
SAZ_RS09445	COG2197	response regulator
SAZ_RS09450	COG4585	Histidine kinase
SAZ_RS09465	COG0445	tRNA wobble uridine modification
SAZ_RS09500	COG2318	DinB family
SAZ_RS09505	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SAZ_RS09545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS09555	COG0584	glycerophosphoryl diester phosphodiesterase
SAZ_RS09565	COG0765	amino acid transport
SAZ_RS09570	COG1126	abc transporter atp-binding protein
SAZ_RS09575	COG0456	acetyltransferase
SAZ_RS09600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAZ_RS09605	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS09610	COG0076	glutamate decarboxylase activity
SAZ_RS09620	COG0477	Major facilitator Superfamily
SAZ_RS09625	COG0154	amidase activity
SAZ_RS09630	COG1309	transcriptional regulator
SAZ_RS09650	COG4221	oxidoreductase activity
SAZ_RS09695	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SAZ_RS09700	COG0179	Fumarylacetoacetate (FAA) hydrolase
SAZ_RS09720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SAZ_RS09725	COG0028	Belongs to the TPP enzyme family
SAZ_RS09740	COG2192	nodulation
SAZ_RS09755	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SAZ_RS09760	COG0148	phosphopyruvate hydratase activity
SAZ_RS09795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SAZ_RS09800	COG0140	phosphoribosyl-ATP diphosphatase activity
SAZ_RS09805	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SAZ_RS09810	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SAZ_RS09810	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SAZ_RS09815	COG3201	nicotinamide mononucleotide transporter
SAZ_RS09830	COG0702	epimerase
SAZ_RS09835	COG1846	Transcriptional regulator
SAZ_RS09835	COG1940	carbohydrate kinase activity
SAZ_RS09840	COG0738	Major facilitator superfamily
SAZ_RS09865	COG2233	PERMEase
SAZ_RS09890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SAZ_RS09900	COG0477	Major facilitator Superfamily
SAZ_RS09915	COG0531	amino acid
SAZ_RS09935	COG2390	Transcriptional regulator
SAZ_RS09940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SAZ_RS09955	COG3209	COG3209 Rhs family protein
SAZ_RS09980	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SAZ_RS09995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SAZ_RS10000	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SAZ_RS10025	COG0284	orotidine-5'-phosphate decarboxylase activity
SAZ_RS10030	COG0167	dihydroorotate dehydrogenase activity
SAZ_RS10035	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SAZ_RS10040	COG0505	Belongs to the CarA family
SAZ_RS10050	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SAZ_RS10055	COG0540	Belongs to the ATCase OTCase family
SAZ_RS10060	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SAZ_RS10070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAZ_RS10075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SAZ_RS10080	COG0006	proline dipeptidase activity
SAZ_RS10090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SAZ_RS10095	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SAZ_RS10100	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SAZ_RS10105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SAZ_RS10110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SAZ_RS10120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SAZ_RS10125	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SAZ_RS10145	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SAZ_RS10165	COG0124	histidyl-tRNA synthetase
SAZ_RS10175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SAZ_RS10180	COG1196	nuclear chromosome segregation
SAZ_RS10185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SAZ_RS10195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAZ_RS10200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAZ_RS10205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAZ_RS10215	COG2255	four-way junction helicase activity
SAZ_RS10220	COG0632	four-way junction helicase activity
SAZ_RS10225	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SAZ_RS10230	COG0217	transcriptional regulatory protein
SAZ_RS10235	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SAZ_RS10240	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SAZ_RS10250	COG0438	transferase activity, transferring glycosyl groups
SAZ_RS10255	COG1560	Kdo2-lipid A biosynthetic process
SAZ_RS10260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SAZ_RS10290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SAZ_RS10305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SAZ_RS10360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAZ_RS10405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SAZ_RS10405	COG1648	precorrin-2 dehydrogenase activity
SAZ_RS10410	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SAZ_RS10425	COG1464	Belongs to the NlpA lipoprotein family
SAZ_RS10430	COG2011	ABC-type metal ion transport system permease component
SAZ_RS10455	COG0584	glycerophosphoryl diester phosphodiesterase
SAZ_RS10470	COG0477	Major facilitator Superfamily
SAZ_RS10480	COG0165	Argininosuccinate lyase
SAZ_RS10485	COG0137	argininosuccinate synthase activity
SAZ_RS10505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAZ_RS10525	COG1438	arginine binding
SAZ_RS10530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SAZ_RS10535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SAZ_RS10540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SAZ_RS10545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SAZ_RS10560	COG1091	dTDP-4-dehydrorhamnose reductase activity
SAZ_RS10585	COG4106	trans-aconitate 2-methyltransferase activity
SAZ_RS10605	COG0697	spore germination
SAZ_RS10615	COG1649	PFAM Uncharacterised BCR, COG1649
SAZ_RS10660	COG0072	phenylalanine-tRNA ligase activity
SAZ_RS10660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAZ_RS10665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SAZ_RS10670	COG5002	protein histidine kinase activity
SAZ_RS10675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SAZ_RS10680	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SAZ_RS10685	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SAZ_RS10690	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SAZ_RS10700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAZ_RS10710	COG1404	Belongs to the peptidase S8 family
SAZ_RS10730	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS10735	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS10740	COG0174	glutamine synthetase
SAZ_RS10745	COG2186	Transcriptional regulator
SAZ_RS10750	COG0531	amino acid
SAZ_RS10755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SAZ_RS10770	COG2233	PERMEase
SAZ_RS10790	COG4176	ABC-type proline glycine betaine transport system permease component
SAZ_RS10795	COG0517	IMP dehydrogenase activity
SAZ_RS10795	COG4175	Glycine betaine
SAZ_RS10800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAZ_RS10825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS10835	COG0805	protein transport
SAZ_RS10840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SAZ_RS10870	COG0544	peptidyl-prolyl cis-trans isomerase activity
SAZ_RS10875	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SAZ_RS10885	COG1609	Transcriptional regulator
SAZ_RS10890	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SAZ_RS10895	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SAZ_RS10905	COG4122	O-methyltransferase activity
SAZ_RS10910	COG1222	aaa ATPase
SAZ_RS10930	COG1994	Peptidase M50
SAZ_RS10930	COG0517	IMP dehydrogenase activity
SAZ_RS10940	COG2197	response regulator
SAZ_RS10945	COG4166	transmembrane transport
SAZ_RS10950	COG0747	negative chemotaxis
SAZ_RS10955	COG0546	phosphoglycolate phosphatase activity
SAZ_RS10960	COG1410	methionine synthase
SAZ_RS10960	COG0646	methionine synthase
SAZ_RS10965	COG1414	Transcriptional regulator
SAZ_RS10970	COG0646	methionine synthase
SAZ_RS10970	COG1410	methionine synthase
SAZ_RS10975	COG1414	Transcriptional regulator
SAZ_RS10980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAZ_RS10985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SAZ_RS10990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SAZ_RS10995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS11000	COG2186	Transcriptional regulator
SAZ_RS11005	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS11010	COG3618	amidohydrolase
SAZ_RS11020	COG4211	Belongs to the binding-protein-dependent transport system permease family
SAZ_RS11025	COG1129	ABC transporter
SAZ_RS11035	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS11040	COG4948	Mandelate Racemase Muconate Lactonizing
SAZ_RS11050	COG0215	cysteine-tRNA ligase activity
SAZ_RS11070	COG0598	Magnesium transport protein CorA
SAZ_RS11080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS11085	COG0667	Aldo Keto reductase
SAZ_RS11115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SAZ_RS11145	COG0745	RESPONSE REGULATOR receiver
SAZ_RS11175	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SAZ_RS11180	COG2149	membrane
SAZ_RS11200	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS11210	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS11220	COG3876	Protein conserved in bacteria
SAZ_RS11235	COG0477	Major facilitator Superfamily
SAZ_RS11345	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS11370	COG1309	transcriptional regulator
SAZ_RS11375	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SAZ_RS11380	COG2188	Transcriptional regulator
SAZ_RS11385	COG2814	Major facilitator Superfamily
SAZ_RS11385	COG0477	Major facilitator Superfamily
SAZ_RS11410	COG3619	membrane
SAZ_RS11420	COG1834	amidinotransferase
SAZ_RS11425	COG1725	Transcriptional regulator
SAZ_RS11430	COG0367	asparagine synthase
SAZ_RS11435	COG2226	methyltransferase
SAZ_RS11445	COG3321	synthase
SAZ_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS11445	COG0604	alcohol dehydrogenase
SAZ_RS11455	COG1522	sequence-specific DNA binding
SAZ_RS11460	COG0531	amino acid
SAZ_RS11470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SAZ_RS11475	COG0587	DNA-directed DNA polymerase activity
SAZ_RS11485	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS11505	COG0330	HflC and HflK could
SAZ_RS11520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS11525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS11530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAZ_RS11535	COG1126	abc transporter atp-binding protein
SAZ_RS11540	COG0765	amino acid transport
SAZ_RS11550	COG0765	amino acid transport
SAZ_RS11575	COG2018	Roadblock/LC7 domain
SAZ_RS11580	COG5002	protein histidine kinase activity
SAZ_RS11585	COG1799	cell septum assembly
SAZ_RS11590	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS11595	COG0477	Major facilitator Superfamily
SAZ_RS11615	COG0671	phosphoesterase, PA-phosphatase related
SAZ_RS11625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SAZ_RS11635	COG0438	transferase activity, transferring glycosyl groups
SAZ_RS11655	COG1160	GTP binding
SAZ_RS11665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SAZ_RS11690	COG1187	pseudouridine synthase activity
SAZ_RS11695	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SAZ_RS11700	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SAZ_RS11715	COG0686	Belongs to the AlaDH PNT family
SAZ_RS11725	COG0494	nUDIX hydrolase
SAZ_RS11730	COG0504	CTP synthase activity
SAZ_RS11735	COG3387	PFAM Glycoside hydrolase 15-related
SAZ_RS11750	COG0438	transferase activity, transferring glycosyl groups
SAZ_RS11760	COG0497	DNA recombination
SAZ_RS11770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SAZ_RS11790	COG1120	ATPase activity
SAZ_RS11795	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAZ_RS11800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAZ_RS11815	COG0647	UMP catabolic process
SAZ_RS11830	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SAZ_RS11855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SAZ_RS11860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SAZ_RS11865	COG0531	amino acid
SAZ_RS11875	COG0569	domain protein
SAZ_RS11910	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SAZ_RS11915	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SAZ_RS11920	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SAZ_RS11925	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SAZ_RS11940	COG0756	dUTP diphosphatase activity
SAZ_RS11965	COG2205	protein histidine kinase activity
SAZ_RS11970	COG0745	RESPONSE REGULATOR receiver
SAZ_RS11975	COG0483	inositol monophosphate 1-phosphatase activity
SAZ_RS11980	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SAZ_RS12015	COG1435	thymidine kinase activity
SAZ_RS12035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAZ_RS12045	COG0739	heme binding
SAZ_RS12055	COG0612	Peptidase, M16
SAZ_RS12060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SAZ_RS12075	COG2197	response regulator
SAZ_RS12080	COG4585	Histidine kinase
SAZ_RS12090	COG0187	DNA topoisomerase II activity
SAZ_RS12105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SAZ_RS12110	COG2186	Transcriptional regulator
SAZ_RS12145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SAZ_RS12175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAZ_RS12180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SAZ_RS12185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SAZ_RS12220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SAZ_RS12235	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SAZ_RS12245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SAZ_RS12260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SAZ_RS12270	COG0583	DNA-binding transcription factor activity
SAZ_RS12280	COG2205	protein histidine kinase activity
SAZ_RS12290	COG1126	abc transporter atp-binding protein
SAZ_RS12295	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
SAZ_RS12300	COG0765	amino acid transport
SAZ_RS12305	COG0765	amino acid transport
SAZ_RS12330	COG0628	permease
SAZ_RS12345	COG1316	TRANSCRIPTIONal
SAZ_RS12350	COG0640	Transcriptional regulator
SAZ_RS12355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SAZ_RS12400	COG1201	RNA secondary structure unwinding
SAZ_RS12405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SAZ_RS12415	COG0783	Belongs to the Dps family
SAZ_RS12420	COG1396	sequence-specific DNA binding
SAZ_RS12430	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SAZ_RS12440	COG0783	Belongs to the Dps family
SAZ_RS12445	COG1396	sequence-specific DNA binding
SAZ_RS12450	COG1058	Belongs to the CinA family
SAZ_RS12450	COG1546	Belongs to the CinA family
SAZ_RS12460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SAZ_RS12470	COG1674	ftsk spoiiie
SAZ_RS12480	COG2205	protein histidine kinase activity
SAZ_RS12480	COG3437	response regulator, receiver
SAZ_RS12480	COG3850	Histidine kinase
SAZ_RS12480	COG4999	Histidine kinase
SAZ_RS12485	COG2208	phosphoserine phosphatase activity
SAZ_RS12485	COG2770	Histidine kinase
SAZ_RS12515	COG2094	Belongs to the DNA glycosylase MPG family
SAZ_RS12525	COG1881	PFAM PEBP family protein
SAZ_RS12550	COG1119	ATPase activity
SAZ_RS12570	COG2197	response regulator
SAZ_RS12575	COG4585	Histidine kinase
SAZ_RS12585	COG3953	SLT domain
SAZ_RS12585	COG5412	phage tail tape measure protein
SAZ_RS12590	COG0842	Transport permease protein
SAZ_RS12590	COG1131	(ABC) transporter
SAZ_RS12590	COG1716	ATPase activity
SAZ_RS12595	COG3830	Belongs to the UPF0237 family
SAZ_RS12595	COG0560	Phosphoserine phosphatase
SAZ_RS12615	COG2186	Transcriptional regulator
SAZ_RS12620	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SAZ_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS12640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SAZ_RS12655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SAZ_RS12660	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SAZ_RS12700	COG0300	oxidoreductase activity
SAZ_RS12730	COG3387	PFAM Glycoside hydrolase 15-related
SAZ_RS12760	COG1302	Protein conserved in bacteria
SAZ_RS12780	COG0488	(ABC) transporter
SAZ_RS12795	COG0235	Class ii aldolase
SAZ_RS12815	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SAZ_RS12820	COG1492	cobalamin metabolic process
SAZ_RS12835	COG1797	cobyrinic acid a,c-diamide synthase activity
SAZ_RS12860	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS12870	COG0640	Transcriptional regulator
SAZ_RS12885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SAZ_RS12890	COG1917	Cupin 2, conserved barrel domain protein
SAZ_RS12895	COG5285	phytanoyl-CoA dioxygenase
SAZ_RS12900	COG1902	pentaerythritol trinitrate reductase activity
SAZ_RS12915	COG2226	methyltransferase
SAZ_RS12930	COG1414	Transcriptional regulator
SAZ_RS12945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SAZ_RS12950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAZ_RS12955	COG2261	transglycosylase associated protein
SAZ_RS12965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS12970	COG2226	methyltransferase
SAZ_RS12990	COG2171	N-acyltransferase activity
SAZ_RS12995	COG3226	Transcriptional regulator
SAZ_RS13000	COG2076	Multidrug Resistance protein
SAZ_RS13010	COG0822	iron-sulfur transferase activity
SAZ_RS13015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SAZ_RS13020	COG0396	ATPase activity
SAZ_RS13030	COG0719	Fe-S assembly protein
SAZ_RS13045	COG1131	(ABC) transporter
SAZ_RS13070	COG0109	protoheme IX farnesyltransferase activity
SAZ_RS13075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SAZ_RS13080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SAZ_RS13095	COG0363	glucosamine-6-phosphate deaminase activity
SAZ_RS13100	COG0166	Belongs to the GPI family
SAZ_RS13115	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SAZ_RS13120	COG0149	triose-phosphate isomerase activity
SAZ_RS13125	COG0126	phosphoglycerate kinase activity
SAZ_RS13130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SAZ_RS13135	COG1481	regulation of sporulation
SAZ_RS13140	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SAZ_RS13145	COG1660	Displays ATPase and GTPase activities
SAZ_RS13150	COG0322	excinuclease ABC activity
SAZ_RS13175	COG2814	Major facilitator Superfamily
SAZ_RS13180	COG1063	alcohol dehydrogenase
SAZ_RS13185	COG1609	Transcriptional regulator
SAZ_RS13195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SAZ_RS13205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SAZ_RS13235	COG0556	nucleotide-excision repair
SAZ_RS13240	COG0584	glycerophosphoryl diester phosphodiesterase
SAZ_RS13305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SAZ_RS13325	COG0237	dephospho-CoA kinase activity
SAZ_RS13350	COG1643	Atp-dependent helicase
SAZ_RS13380	COG2050	protein possibly involved in aromatic compounds catabolism
SAZ_RS13390	COG0559	Belongs to the binding-protein-dependent transport system permease family
SAZ_RS13435	COG0737	Belongs to the 5'-nucleotidase family
SAZ_RS13465	COG1470	cell adhesion involved in biofilm formation
SAZ_RS13465	COG0366	Alpha amylase catalytic
SAZ_RS13475	COG2197	response regulator
SAZ_RS13490	COG2267	carboxylic ester hydrolase activity
SAZ_RS13510	COG3467	pyridoxamine 5'-phosphate
SAZ_RS13525	COG0640	Transcriptional regulator
SAZ_RS13540	COG0067	glutamate synthase
SAZ_RS13540	COG0069	glutamate synthase activity
SAZ_RS13540	COG0070	glutamate synthase
SAZ_RS13555	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SAZ_RS13565	COG0159	tryptophan synthase activity
SAZ_RS13570	COG0133	tryptophan synthase activity
SAZ_RS13575	COG0134	indole-3-glycerol-phosphate synthase activity
SAZ_RS13600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SAZ_RS13610	COG0583	DNA-binding transcription factor activity
SAZ_RS13620	COG1053	succinate dehydrogenase
SAZ_RS13625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SAZ_RS13630	COG0107	imidazoleglycerol-phosphate synthase activity
SAZ_RS13635	COG0251	oxidation-reduction process
SAZ_RS13640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SAZ_RS13645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SAZ_RS13655	COG0131	Imidazoleglycerol-phosphate dehydratase
SAZ_RS13660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SAZ_RS13665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SAZ_RS13680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SAZ_RS13700	COG1432	Conserved Protein
SAZ_RS13705	COG0587	DNA-directed DNA polymerase activity
SAZ_RS13755	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SAZ_RS13770	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SAZ_RS13775	COG3599	regulation of cell shape
SAZ_RS13785	COG1799	cell septum assembly
SAZ_RS13790	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SAZ_RS13800	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SAZ_RS13805	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SAZ_RS13810	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SAZ_RS13820	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SAZ_RS13825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SAZ_RS13835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SAZ_RS13840	COG0768	penicillin binding
SAZ_RS13850	COG0275	rRNA processing
SAZ_RS13860	COG0714	Associated with various cellular activities
SAZ_RS13880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SAZ_RS13890	COG1716	ATPase activity
SAZ_RS13890	COG1131	(ABC) transporter
SAZ_RS13890	COG0842	Transport permease protein
SAZ_RS13900	COG1309	transcriptional regulator
SAZ_RS13910	COG1233	COG1233 Phytoene dehydrogenase and related
SAZ_RS13925	COG0352	thiamine-phosphate diphosphorylase activity
SAZ_RS13940	COG2022	thiamine diphosphate biosynthetic process
SAZ_RS13940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SAZ_RS13950	COG2022	thiamine diphosphate biosynthetic process
SAZ_RS13955	COG0789	Transcriptional regulator
SAZ_RS13960	COG0515	serine threonine protein kinase
SAZ_RS13960	COG2815	serine threonine protein kinase
SAZ_RS13965	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SAZ_RS13970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SAZ_RS13975	COG2193	ferroxidase activity
SAZ_RS13980	COG0243	molybdopterin cofactor binding
SAZ_RS13985	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SAZ_RS13995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SAZ_RS14000	COG0205	6-phosphofructokinase activity
SAZ_RS14005	COG2197	response regulator
SAZ_RS14035	COG1940	carbohydrate kinase activity
SAZ_RS14045	COG0003	Pfam Anion-transporting ATPase
SAZ_RS14065	COG0438	transferase activity, transferring glycosyl groups
SAZ_RS14080	COG0791	NLP P60 protein
SAZ_RS14110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SAZ_RS14115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SAZ_RS14120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SAZ_RS14125	COG0723	plastoquinol--plastocyanin reductase activity
SAZ_RS14130	COG2010	Cytochrome c
SAZ_RS14135	COG1845	cytochrome c oxidase, subunit III
SAZ_RS14145	COG1376	ErfK ybiS ycfS ynhG family protein
SAZ_RS14155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SAZ_RS14165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SAZ_RS14170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SAZ_RS14175	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SAZ_RS14185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAZ_RS14200	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SAZ_RS14225	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SAZ_RS14230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAZ_RS14235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SAZ_RS14240	COG2197	response regulator
SAZ_RS14245	COG4585	Histidine kinase
SAZ_RS14280	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SAZ_RS14290	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SAZ_RS14295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SAZ_RS14300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAZ_RS14305	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAZ_RS14315	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SAZ_RS14355	COG0321	lipoyl(octanoyl) transferase activity
SAZ_RS14360	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SAZ_RS14395	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS14415	COG0745	RESPONSE REGULATOR receiver
SAZ_RS14435	COG2197	response regulator
SAZ_RS14480	COG0366	Alpha amylase catalytic
SAZ_RS14485	COG3833	ABC-type maltose transport systems, permease component
SAZ_RS14490	COG1175	transmembrane transport
SAZ_RS14495	COG2182	Extracellular solute-binding protein
SAZ_RS14500	COG0366	Alpha amylase catalytic
SAZ_RS14505	COG1609	Transcriptional regulator
SAZ_RS14515	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SAZ_RS14530	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SAZ_RS14535	COG0174	glutamine synthetase
SAZ_RS14625	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SAZ_RS14630	COG0174	glutamine synthetase
SAZ_RS14635	COG2267	carboxylic ester hydrolase activity
SAZ_RS14645	COG2132	Multicopper oxidase
SAZ_RS14650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SAZ_RS14650	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SAZ_RS14655	COG2814	Major facilitator Superfamily
SAZ_RS14665	COG1309	transcriptional regulator
SAZ_RS14670	COG0477	Major facilitator Superfamily
SAZ_RS14675	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SAZ_RS14695	COG1994	Peptidase M50
SAZ_RS14715	COG1175	transmembrane transport
SAZ_RS14725	COG2186	Transcriptional regulator
SAZ_RS14730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SAZ_RS14750	COG5398	heme oxygenase
SAZ_RS14780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAZ_RS14785	COG2814	Major facilitator Superfamily
SAZ_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS14875	COG0789	Transcriptional regulator
SAZ_RS14890	COG3022	response to hydroperoxide
SAZ_RS14895	COG0800	Aldolase
SAZ_RS14915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAZ_RS14925	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS14935	COG2030	dehydratase
SAZ_RS14940	COG4585	Histidine kinase
SAZ_RS14945	COG2197	response regulator
SAZ_RS14955	COG0183	Belongs to the thiolase family
SAZ_RS14960	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS14980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS15005	COG0438	transferase activity, transferring glycosyl groups
SAZ_RS15010	COG1309	transcriptional regulator
SAZ_RS15045	COG3845	ABC transporter
SAZ_RS15055	COG0183	Belongs to the thiolase family
SAZ_RS15060	COG2124	cytochrome p450
SAZ_RS15070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SAZ_RS15075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SAZ_RS15195	COG1072	(Pantothenic acid kinase))
SAZ_RS15205	COG0596	Alpha beta hydrolase
SAZ_RS15210	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SAZ_RS15220	COG2259	Doxx family
SAZ_RS15250	COG2186	Transcriptional regulator
SAZ_RS15270	COG1358	cellular component organization or biogenesis
SAZ_RS15315	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SAZ_RS15325	COG0477	Major facilitator Superfamily
SAZ_RS15330	COG1309	transcriptional regulator
SAZ_RS15345	COG4585	Histidine kinase
SAZ_RS15350	COG2197	response regulator
SAZ_RS15365	COG0667	Aldo Keto reductase
SAZ_RS15370	COG0789	Transcriptional regulator
SAZ_RS15395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SAZ_RS15400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAZ_RS15405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAZ_RS15435	COG1309	transcriptional regulator
SAZ_RS15445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAZ_RS15455	COG1172	Belongs to the binding-protein-dependent transport system permease family
SAZ_RS15460	COG1129	ABC transporter
SAZ_RS15465	COG1609	Transcriptional regulator
SAZ_RS15470	COG1764	response to oxidative stress
SAZ_RS15475	COG2130	NADP-dependent
SAZ_RS15485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SAZ_RS15510	COG0500	methyltransferase
SAZ_RS15515	COG4981	capsule polysaccharide biosynthetic process
SAZ_RS15555	COG1077	Cell shape determining protein MreB Mrl
SAZ_RS15560	COG0588	phosphoglycerate mutase activity
SAZ_RS15565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAZ_RS15600	COG1070	Carbohydrate kinase
SAZ_RS15610	COG0358	DNA primase activity
SAZ_RS15630	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SAZ_RS15640	COG0243	molybdopterin cofactor binding
SAZ_RS15645	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SAZ_RS15675	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SAZ_RS15705	COG0667	Aldo Keto reductase
SAZ_RS15725	COG1473	amidohydrolase
SAZ_RS15730	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS15740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SAZ_RS15745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SAZ_RS15745	COG2146	nitrite reductase [NAD(P)H] activity
SAZ_RS15760	COG0531	amino acid
SAZ_RS15770	COG1175	transmembrane transport
SAZ_RS15775	COG0395	ABC-type sugar transport system, permease component
SAZ_RS15780	COG2175	clavaminate synthase activity
SAZ_RS15810	COG2015	COG2015, Alkyl sulfatase and related hydrolases
SAZ_RS15815	COG0574	Belongs to the PEP-utilizing enzyme family
SAZ_RS15815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SAZ_RS15835	COG0477	Major facilitator Superfamily
SAZ_RS15840	COG0667	Aldo Keto reductase
SAZ_RS15850	COG0423	glycine-tRNA ligase activity
SAZ_RS15860	COG1121	(ABC) transporter
SAZ_RS15865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAZ_RS15885	COG1228	amidohydrolase
SAZ_RS15890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SAZ_RS15900	COG1228	amidohydrolase
SAZ_RS15905	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SAZ_RS15910	COG1381	Involved in DNA repair and RecF pathway recombination
SAZ_RS15950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SAZ_RS15970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SAZ_RS15985	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SAZ_RS16000	COG1486	melibiose metabolic process
SAZ_RS16015	COG4948	Mandelate Racemase Muconate Lactonizing
SAZ_RS16025	COG1234	tRNA 3'-trailer cleavage
SAZ_RS16030	COG0537	adenosine 5'-monophosphoramidase activity
SAZ_RS16055	COG0484	heat shock protein binding
SAZ_RS16060	COG1420	regulation of RNA biosynthetic process
SAZ_RS16090	COG1022	Amp-dependent synthetase and ligase
SAZ_RS16095	COG0481	GTPase activity
SAZ_RS16100	COG0268	Binds directly to 16S ribosomal RNA
SAZ_RS16130	COG1555	photosystem II stabilization
SAZ_RS16135	COG1307	EDD domain protein, DegV family
SAZ_RS16145	COG0495	leucyl-tRNA aminoacylation
SAZ_RS16175	COG0588	phosphoglycerate mutase activity
SAZ_RS16180	COG0799	negative regulation of ribosome biogenesis
SAZ_RS16190	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SAZ_RS16200	COG0501	Belongs to the peptidase M48B family
SAZ_RS16215	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SAZ_RS16225	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SAZ_RS16235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SAZ_RS16240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SAZ_RS16245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SAZ_RS16250	COG1530	ribonuclease E activity
SAZ_RS16280	COG0772	Belongs to the SEDS family
SAZ_RS16285	COG0768	penicillin binding
SAZ_RS16300	COG1077	Cell shape determining protein MreB Mrl
SAZ_RS16305	COG0105	UTP biosynthetic process
SAZ_RS16315	COG0285	dihydrofolate synthase activity
SAZ_RS16320	COG0768	penicillin binding
SAZ_RS16330	COG0525	valine-tRNA ligase activity
SAZ_RS16340	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SAZ_RS16345	COG0740	serine-type endopeptidase activity
SAZ_RS16350	COG0740	serine-type endopeptidase activity
SAZ_RS16355	COG0544	peptidyl-prolyl cis-trans isomerase activity
SAZ_RS16380	COG0475	glutathione-regulated potassium exporter activity
SAZ_RS16390	COG4552	Acetyltransferase involved in intracellular survival and related
SAZ_RS16400	COG0698	ribose 5-phosphate isomerase
SAZ_RS16405	COG1113	amino acid transport
SAZ_RS16415	COG1113	amino acid transport
SAZ_RS16420	COG1113	amino acid transport
SAZ_RS16430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SAZ_RS16435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SAZ_RS16465	COG4266	Belongs to the allantoicase family
SAZ_RS16510	COG0668	transmembrane transport
SAZ_RS16520	COG1940	carbohydrate kinase activity
SAZ_RS16520	COG1846	Transcriptional regulator
SAZ_RS16530	COG1175	transmembrane transport
SAZ_RS16535	COG0395	ABC-type sugar transport system, permease component
SAZ_RS16540	COG1486	melibiose metabolic process
SAZ_RS16555	COG2188	Transcriptional regulator
SAZ_RS16565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAZ_RS16600	COG2346	COG2346, Truncated hemoglobins
SAZ_RS16630	COG0629	single-stranded DNA binding
SAZ_RS16660	COG2391	methyltransferase activity
SAZ_RS16665	COG0515	serine threonine protein kinase
SAZ_RS16665	COG2815	serine threonine protein kinase
SAZ_RS16680	COG1077	Cell shape determining protein MreB Mrl
SAZ_RS16690	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SAZ_RS16705	COG1131	(ABC) transporter
SAZ_RS16720	COG3962	Belongs to the TPP enzyme family
SAZ_RS16725	COG3718	enzyme involved in inositol metabolism
SAZ_RS16735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAZ_RS16745	COG0673	inositol 2-dehydrogenase activity
SAZ_RS16750	COG2814	Major facilitator Superfamily
SAZ_RS16770	COG0673	inositol 2-dehydrogenase activity
SAZ_RS16785	COG2608	mercury ion transmembrane transporter activity
SAZ_RS16795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SAZ_RS16810	COG0673	inositol 2-dehydrogenase activity
SAZ_RS16815	COG1609	Transcriptional regulator
SAZ_RS16825	COG1472	Belongs to the glycosyl hydrolase 3 family
SAZ_RS16845	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SAZ_RS16860	COG0028	Belongs to the TPP enzyme family
SAZ_RS16910	COG1946	Acyl-CoA thioesterase
SAZ_RS16920	COG1309	transcriptional regulator
SAZ_RS16925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SAZ_RS16940	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS16955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SAZ_RS16960	COG0589	response to stress
SAZ_RS16965	COG4977	sequence-specific DNA binding
SAZ_RS16970	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SAZ_RS16980	COG2910	NAD(P)H-binding
SAZ_RS16990	COG3979	chitinase
SAZ_RS17025	COG0297	glycogen (starch) synthase activity
SAZ_RS17030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAZ_RS17035	COG0438	transferase activity, transferring glycosyl groups
SAZ_RS17095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS17115	COG0154	amidase activity
SAZ_RS17130	COG0765	amino acid transport
SAZ_RS17135	COG0765	amino acid transport
SAZ_RS17140	COG1126	abc transporter atp-binding protein
SAZ_RS17155	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS17160	COG3397	chitin binding
SAZ_RS17165	COG2318	DinB family
SAZ_RS17225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SAZ_RS17230	COG2188	Transcriptional regulator
SAZ_RS17235	COG1940	carbohydrate kinase activity
SAZ_RS17240	COG0673	inositol 2-dehydrogenase activity
SAZ_RS17250	COG0706	membrane insertase activity
SAZ_RS17260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SAZ_RS17270	COG3764	Sortase (surface protein transpeptidase)
SAZ_RS17275	COG2733	membrane
SAZ_RS17305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAZ_RS17315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SAZ_RS17330	COG2205	protein histidine kinase activity
SAZ_RS17360	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SAZ_RS17370	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SAZ_RS17375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAZ_RS17380	COG1263	PTS System
SAZ_RS17385	COG1263	PTS System
SAZ_RS17390	COG1234	tRNA 3'-trailer cleavage
SAZ_RS17415	COG1113	amino acid transport
SAZ_RS17425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SAZ_RS17435	COG1335	isochorismatase
SAZ_RS17470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAZ_RS17475	COG0222	ribosome binding
SAZ_RS17505	COG0277	FAD linked oxidase domain protein
SAZ_RS17510	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SAZ_RS17520	COG1174	glycine betaine transport
SAZ_RS17530	COG1174	glycine betaine transport
SAZ_RS17575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SAZ_RS17590	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SAZ_RS17600	COG2814	Major facilitator Superfamily
SAZ_RS17605	COG0583	DNA-binding transcription factor activity
SAZ_RS17615	COG1678	Uncharacterized ACR, COG1678
SAZ_RS17620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SAZ_RS17625	COG0776	regulation of translation
SAZ_RS17635	COG3973	AAA domain
SAZ_RS17670	COG2223	nitrite transmembrane transporter activity
SAZ_RS17685	COG0583	DNA-binding transcription factor activity
SAZ_RS17695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SAZ_RS17700	COG0793	Belongs to the peptidase S41A family
SAZ_RS17705	COG2177	Part of the ABC transporter FtsEX involved in
SAZ_RS17710	COG2884	Cell division ATP-binding protein ftsE
SAZ_RS17725	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SAZ_RS17730	COG0515	serine threonine protein kinase
SAZ_RS17735	COG0515	serine threonine protein kinase
SAZ_RS17750	COG1653	transport
SAZ_RS17755	COG1175	transmembrane transport
SAZ_RS17760	COG0395	ABC-type sugar transport system, permease component
SAZ_RS17765	COG0395	ABC-type sugar transport system, permease component
SAZ_RS17780	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAZ_RS17815	COG0463	Glycosyl transferase, family 2
SAZ_RS17835	COG1309	transcriptional regulator
SAZ_RS17845	COG1134	teichoic acid transport
SAZ_RS17845	COG1388	LysM domain
SAZ_RS17850	COG2902	Dehydrogenase
SAZ_RS17855	COG0546	phosphoglycolate phosphatase activity
SAZ_RS17875	COG0653	protein targeting
SAZ_RS17885	COG3214	Protein conserved in bacteria
SAZ_RS17890	COG2197	response regulator
SAZ_RS17895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SAZ_RS17905	COG0823	Involved in the tonB-independent uptake of proteins
SAZ_RS17910	COG5002	protein histidine kinase activity
SAZ_RS17910	COG5000	phosphorelay sensor kinase activity
SAZ_RS17915	COG0745	RESPONSE REGULATOR receiver
SAZ_RS17920	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SAZ_RS17940	COG0714	Associated with various cellular activities
SAZ_RS18015	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SAZ_RS18025	COG1482	cell wall glycoprotein biosynthetic process
SAZ_RS18035	COG2835	tetraacyldisaccharide 4'-kinase activity
SAZ_RS18040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAZ_RS18075	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SAZ_RS18080	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SAZ_RS18080	COG0778	Nitroreductase
SAZ_RS18115	COG1316	TRANSCRIPTIONal
SAZ_RS18125	COG1316	TRANSCRIPTIONal
SAZ_RS18145	COG1316	TRANSCRIPTIONal
SAZ_RS18165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SAZ_RS18210	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SAZ_RS18245	COG2205	protein histidine kinase activity
SAZ_RS18250	COG0745	RESPONSE REGULATOR receiver
SAZ_RS18255	COG3104	oligopeptide transport
SAZ_RS18280	COG1366	Belongs to the anti-sigma-factor antagonist family
SAZ_RS18285	COG1191	sigma factor activity
SAZ_RS18290	COG1228	amidohydrolase
SAZ_RS18300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SAZ_RS18305	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SAZ_RS18320	COG1131	(ABC) transporter
SAZ_RS18350	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SAZ_RS18365	COG2755	lipolytic protein G-D-S-L family
SAZ_RS18370	COG0183	Belongs to the thiolase family
SAZ_RS18395	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAZ_RS18410	COG1136	(ABC) transporter
SAZ_RS18415	COG1136	(ABC) transporter
SAZ_RS18420	COG0577	efflux transmembrane transporter activity
SAZ_RS18420	COG1136	(ABC) transporter
SAZ_RS18425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SAZ_RS18450	COG0148	phosphopyruvate hydratase activity
SAZ_RS18465	COG2124	cytochrome p450
SAZ_RS18475	COG2814	Major facilitator Superfamily
SAZ_RS18510	COG2815	serine threonine protein kinase
SAZ_RS18510	COG0515	serine threonine protein kinase
SAZ_RS18550	COG2814	Major facilitator Superfamily
SAZ_RS18580	COG4585	Histidine kinase
SAZ_RS18590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SAZ_RS18595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SAZ_RS18600	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SAZ_RS18605	COG0193	aminoacyl-tRNA hydrolase activity
SAZ_RS18610	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SAZ_RS18620	COG1309	transcriptional regulator
SAZ_RS18625	COG4106	trans-aconitate 2-methyltransferase activity
SAZ_RS18645	COG2197	response regulator
SAZ_RS18650	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SAZ_RS18680	COG0488	(ABC) transporter
SAZ_RS18710	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SAZ_RS18715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SAZ_RS18720	COG3584	3D domain protein
SAZ_RS18720	COG3583	domain protein
SAZ_RS18725	COG0084	hydrolase, TatD family'
SAZ_RS18750	COG0442	prolyl-tRNA aminoacylation
SAZ_RS18770	COG1122	ATPase activity
SAZ_RS18780	COG0310	cobalt ion transport
SAZ_RS18790	COG0793	Belongs to the peptidase S41A family
SAZ_RS18790	COG4946	Tricorn protease homolog
SAZ_RS18800	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS18810	COG2072	flavoprotein involved in K transport
SAZ_RS18815	COG0789	Transcriptional regulator
SAZ_RS18820	COG0708	Exodeoxyribonuclease III
SAZ_RS18825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SAZ_RS18865	COG1131	(ABC) transporter
SAZ_RS18875	COG1725	Transcriptional regulator
SAZ_RS18880	COG2205	protein histidine kinase activity
SAZ_RS18890	COG0789	Transcriptional regulator
SAZ_RS18895	COG1819	glycosyl
SAZ_RS18915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAZ_RS18920	COG0315	cyclic pyranopterin monophosphate synthase activity
SAZ_RS18920	COG0521	Mo-molybdopterin cofactor biosynthetic process
SAZ_RS18925	COG0315	cyclic pyranopterin monophosphate synthase activity
SAZ_RS18935	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SAZ_RS18940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SAZ_RS18950	COG3263	regulation of cellular component size
SAZ_RS18960	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SAZ_RS18965	COG1970	mechanosensitive ion channel activity
SAZ_RS18975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAZ_RS18980	COG0477	Major facilitator Superfamily
SAZ_RS18985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SAZ_RS18990	COG2188	Transcriptional regulator
SAZ_RS18995	COG0730	response to heat
SAZ_RS19030	COG3191	aminopeptidase activity
SAZ_RS19050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SAZ_RS19070	COG1105	Belongs to the carbohydrate kinase PfkB family
SAZ_RS19075	COG1349	DNA-binding transcription factor activity
SAZ_RS19085	COG1247	-acetyltransferase
SAZ_RS19110	COG1846	Transcriptional regulator
SAZ_RS19135	COG1309	transcriptional regulator
SAZ_RS19175	COG0514	ATP-dependent DNA helicase (RecQ)
SAZ_RS19180	COG2205	protein histidine kinase activity
SAZ_RS19200	COG0640	Transcriptional regulator
SAZ_RS19220	COG0640	Transcriptional regulator
SAZ_RS19230	COG1686	Belongs to the peptidase S11 family
SAZ_RS19255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAZ_RS19260	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS19275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAZ_RS19285	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SAZ_RS19310	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS19410	COG1024	Enoyl-CoA hydratase
SAZ_RS19430	COG1309	transcriptional regulator
SAZ_RS19440	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS19470	COG1024	Enoyl-CoA hydratase
SAZ_RS19490	COG2271	Major facilitator Superfamily
SAZ_RS19500	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS19505	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS19520	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS19525	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS19530	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS19555	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SAZ_RS19565	COG0516	GMP reductase activity
SAZ_RS19575	COG1595	DNA-templated transcription, initiation
SAZ_RS19580	COG2197	response regulator
SAZ_RS19590	COG0583	DNA-binding transcription factor activity
SAZ_RS19600	COG4221	oxidoreductase activity
SAZ_RS19610	COG0459	protein refolding
SAZ_RS19615	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SAZ_RS19620	COG0772	Belongs to the SEDS family
SAZ_RS19635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SAZ_RS19660	COG0802	atpase or kinase
SAZ_RS19670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SAZ_RS19680	COG0736	holo-[acyl-carrier-protein] synthase activity
SAZ_RS19685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SAZ_RS19695	COG1072	(Pantothenic acid kinase))
SAZ_RS19700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAZ_RS19705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SAZ_RS19710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SAZ_RS19720	COG0101	tRNA pseudouridine synthase activity
SAZ_RS19725	COG0203	ribosomal protein L17
SAZ_RS19730	COG0202	RNA polymerase activity
SAZ_RS19735	COG0202	RNA polymerase activity
SAZ_RS19740	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SAZ_RS19745	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SAZ_RS19750	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SAZ_RS19755	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SAZ_RS19760	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SAZ_RS19770	COG0563	adenylate kinase activity
SAZ_RS19780	COG0200	Binds to the 23S rRNA
SAZ_RS19785	COG1841	ribosomal large subunit assembly
SAZ_RS19790	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SAZ_RS19795	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SAZ_RS19800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SAZ_RS19805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SAZ_RS19810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SAZ_RS19815	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SAZ_RS19820	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SAZ_RS19825	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SAZ_RS19830	COG0255	Belongs to the universal ribosomal protein uL29 family
SAZ_RS19835	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SAZ_RS19840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SAZ_RS19845	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SAZ_RS19850	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SAZ_RS19855	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SAZ_RS19860	COG0089	rRNA binding
SAZ_RS19865	COG0088	Forms part of the polypeptide exit tunnel
SAZ_RS19870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SAZ_RS19875	COG0051	transcription antitermination factor activity, RNA binding
SAZ_RS19880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SAZ_RS19885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SAZ_RS19890	COG0049	tRNA binding
SAZ_RS19895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SAZ_RS19905	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SAZ_RS19910	COG0085	RNA polymerase activity
SAZ_RS19915	COG0222	ribosome binding
SAZ_RS19920	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SAZ_RS19930	COG0081	regulation of translation
SAZ_RS19935	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SAZ_RS19940	COG0250	Participates in transcription elongation, termination and antitermination
SAZ_RS19955	COG0436	Aminotransferase
SAZ_RS19960	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SAZ_RS19965	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SAZ_RS19975	COG2030	dehydratase
SAZ_RS19980	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SAZ_RS20010	COG1666	GTP binding
SAZ_RS20015	COG3304	Inner membrane component domain
SAZ_RS20020	COG0501	Belongs to the peptidase M48B family
SAZ_RS20025	COG1007	ATP synthesis coupled electron transport
SAZ_RS20035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SAZ_RS20040	COG0713	ATP synthesis coupled electron transport
SAZ_RS20045	COG0839	Belongs to the complex I subunit 6 family
SAZ_RS20050	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SAZ_RS20055	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SAZ_RS20060	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SAZ_RS20065	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SAZ_RS20070	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SAZ_RS20085	COG4585	Histidine kinase
SAZ_RS20090	COG4585	Histidine kinase
SAZ_RS20100	COG0674	pyruvate-flavodoxin oxidoreductase activity
SAZ_RS20100	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SAZ_RS20105	COG1013	pyruvate-flavodoxin oxidoreductase activity
SAZ_RS20140	COG0142	geranyltranstransferase activity
SAZ_RS20160	COG1007	ATP synthesis coupled electron transport
SAZ_RS20170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SAZ_RS20175	COG0713	ATP synthesis coupled electron transport
SAZ_RS20180	COG0839	Belongs to the complex I subunit 6 family
SAZ_RS20185	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SAZ_RS20190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SAZ_RS20195	COG1034	ATP synthesis coupled electron transport
SAZ_RS20200	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SAZ_RS20210	COG0649	NAD binding
SAZ_RS20215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SAZ_RS20220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SAZ_RS20245	COG2226	methyltransferase
SAZ_RS20255	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SAZ_RS20265	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SAZ_RS20270	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SAZ_RS20275	COG1278	Cold shock
SAZ_RS20290	COG1309	transcriptional regulator
SAZ_RS20300	COG1301	dicarboxylic acid transport
SAZ_RS20315	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SAZ_RS20325	COG0163	prenyltransferase activity
SAZ_RS20345	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SAZ_RS20350	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SAZ_RS20390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SAZ_RS20395	COG1333	cytochrome c biogenesis protein
SAZ_RS20400	COG0785	Cytochrome C biogenesis protein
SAZ_RS20415	COG0406	alpha-ribazole phosphatase activity
SAZ_RS20420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SAZ_RS20450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SAZ_RS20455	COG1742	UPF0060 membrane protein
SAZ_RS20470	COG1690	Belongs to the RtcB family
SAZ_RS20495	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SAZ_RS20500	COG0018	arginyl-trna synthetase
SAZ_RS20520	COG0113	porphobilinogen synthase activity
SAZ_RS20525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SAZ_RS20525	COG1648	precorrin-2 dehydrogenase activity
SAZ_RS20530	COG0181	hydroxymethylbilane synthase activity
SAZ_RS20535	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SAZ_RS20540	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SAZ_RS20585	COG0123	including yeast histone deacetylase and acetoin utilization protein
SAZ_RS20595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAZ_RS20620	COG1846	Transcriptional regulator
SAZ_RS20635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SAZ_RS20660	COG0579	oxidoreductase
SAZ_RS20665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SAZ_RS20705	COG0513	Belongs to the DEAD box helicase family
SAZ_RS20745	COG1643	Atp-dependent helicase
SAZ_RS20780	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SAZ_RS20795	COG3119	arylsulfatase activity
SAZ_RS20815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAZ_RS20820	COG0047	phosphoribosylformylglycinamidine synthase activity
SAZ_RS20825	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAZ_RS20850	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SAZ_RS20855	COG2814	Major facilitator Superfamily
SAZ_RS20860	COG0583	DNA-binding transcription factor activity
SAZ_RS20880	COG0151	Belongs to the GarS family
SAZ_RS20895	COG1802	Transcriptional regulator
SAZ_RS20900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SAZ_RS20910	COG0515	serine threonine protein kinase
SAZ_RS20910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SAZ_RS20915	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SAZ_RS20930	COG1131	(ABC) transporter
SAZ_RS20935	COG3559	Exporter of polyketide antibiotics
SAZ_RS20940	COG2197	response regulator
SAZ_RS20945	COG4585	Histidine kinase
SAZ_RS20955	COG3844	kynureninase activity
SAZ_RS20975	COG0477	Major facilitator Superfamily
SAZ_RS20980	COG0191	fructose-bisphosphate aldolase activity
SAZ_RS20985	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SAZ_RS20990	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SAZ_RS21015	COG0542	response to heat
SAZ_RS21030	COG0789	Transcriptional regulator
SAZ_RS21035	COG0484	heat shock protein binding
SAZ_RS21040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SAZ_RS21045	COG0443	Heat shock 70 kDa protein
SAZ_RS21050	COG0443	Heat shock 70 kDa protein
SAZ_RS21055	COG0247	lactate metabolic process
SAZ_RS21055	COG2181	nitrate reductase activity
SAZ_RS21065	COG2755	lipolytic protein G-D-S-L family
SAZ_RS21075	COG0717	Belongs to the dCTP deaminase family
SAZ_RS21175	COG0105	UTP biosynthetic process
SAZ_RS21215	COG0432	Pfam Uncharacterised protein family UPF0047
SAZ_RS21230	COG0531	amino acid
SAZ_RS21305	COG1674	ftsk spoiiie
SAZ_RS21325	COG2301	Belongs to the HpcH HpaI aldolase family
SAZ_RS21330	COG2301	Belongs to the HpcH HpaI aldolase family
SAZ_RS21355	COG3629	intracellular signal transduction
SAZ_RS21355	COG3903	Transcriptional regulator
SAZ_RS21420	COG1316	TRANSCRIPTIONal
SAZ_RS21465	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SAZ_RS21485	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SAZ_RS21515	COG1174	glycine betaine transport
SAZ_RS21520	COG1174	glycine betaine transport
SAZ_RS21540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAZ_RS21545	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SAZ_RS21570	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS21575	COG1362	aminopeptidase activity
SAZ_RS21580	COG3903	Transcriptional regulator
SAZ_RS21580	COG3629	intracellular signal transduction
SAZ_RS21625	COG2814	Major facilitator Superfamily
SAZ_RS21645	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAZ_RS21650	COG0022	dehydrogenase e1 component
SAZ_RS21675	COG0515	serine threonine protein kinase
SAZ_RS21680	COG0515	serine threonine protein kinase
SAZ_RS21700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SAZ_RS21710	COG0746	molybdenum cofactor guanylyltransferase activity
SAZ_RS21730	COG1522	sequence-specific DNA binding
SAZ_RS21735	COG1309	transcriptional regulator
SAZ_RS21740	COG1250	3-hydroxyacyl-CoA dehydrogenase
SAZ_RS21765	COG3396	Phenylacetate-CoA oxygenase
SAZ_RS21770	COG3460	Phenylacetate-CoA oxygenase
SAZ_RS21775	COG3396	Phenylacetate-CoA oxygenase
SAZ_RS21780	COG2151	metal-sulfur cluster biosynthetic enzyme
SAZ_RS21785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SAZ_RS21825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SAZ_RS21830	COG2814	Major facilitator Superfamily
SAZ_RS21835	COG0583	DNA-binding transcription factor activity
SAZ_RS21845	COG1716	ATPase activity
SAZ_RS21850	COG1716	ATPase activity
SAZ_RS21865	COG0768	penicillin binding
SAZ_RS21870	COG0515	serine threonine protein kinase
SAZ_RS21875	COG3764	Sortase (surface protein transpeptidase)
SAZ_RS21880	COG0515	serine threonine protein kinase
SAZ_RS21885	COG3764	Sortase (surface protein transpeptidase)
SAZ_RS21890	COG3764	Sortase (surface protein transpeptidase)
SAZ_RS21905	COG3764	Sortase (surface protein transpeptidase)
SAZ_RS21920	COG0705	Rhomboid family
SAZ_RS21950	COG0515	serine threonine protein kinase
SAZ_RS21975	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SAZ_RS21980	COG0187	DNA topoisomerase II activity
SAZ_RS21985	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SAZ_RS21990	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SAZ_RS21995	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SAZ_RS22000	COG0592	DNA-directed DNA polymerase activity
SAZ_RS22010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SAZ_RS22015	COG0594	ribonuclease P activity
SAZ_RS22020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SAZ_RS22025	COG0706	membrane insertase activity
SAZ_RS22035	COG0357	Ribosomal RNA small subunit methyltransferase G
SAZ_RS22040	COG1192	Involved in chromosome partitioning
SAZ_RS22055	COG3118	belongs to the thioredoxin family
SAZ_RS22065	COG3118	belongs to the thioredoxin family
SAZ_RS22070	COG0492	ferredoxin-NADP+ reductase activity
SAZ_RS22080	COG0515	serine threonine protein kinase
SAZ_RS22080	COG2815	serine threonine protein kinase
SAZ_RS22095	COG0617	tRNA 3'-terminal CCA addition
SAZ_RS22110	COG1260	myo-inositol-1-phosphate synthase
SAZ_RS22120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAZ_RS22120	COG4499	WXG100 protein secretion system (Wss), protein YukC
SAZ_RS22145	COG0360	Binds together with S18 to 16S ribosomal RNA
SAZ_RS22150	COG0629	single-stranded DNA binding
SAZ_RS22155	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SAZ_RS22160	COG0359	binds to the 23S rRNA
SAZ_RS22175	COG0305	Participates in initiation and elongation during chromosome replication
SAZ_RS22180	COG1733	regulation of RNA biosynthetic process
SAZ_RS22200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAZ_RS22220	COG1846	Transcriptional regulator
SAZ_RS22255	COG0626	cystathionine gamma-synthase activity
SAZ_RS22260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SAZ_RS22265	COG1950	PFAM Membrane protein of
SAZ_RS22270	COG0662	Cupin 2, conserved barrel domain protein
SAZ_RS22295	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SAZ_RS22305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SAZ_RS22310	COG1609	Transcriptional regulator
SAZ_RS22315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SAZ_RS22325	COG1271	oxidase subunit
SAZ_RS22330	COG1294	oxidase, subunit
SAZ_RS22335	COG4988	ABC transporter
SAZ_RS22345	COG0561	phosphatase activity
SAZ_RS22355	COG0501	Belongs to the peptidase M48B family
SAZ_RS22365	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SAZ_RS22380	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SAZ_RS22385	COG0789	Transcriptional regulator
SAZ_RS22430	COG2807	transmembrane transport
SAZ_RS22435	COG2186	Transcriptional regulator
SAZ_RS22460	COG0583	DNA-binding transcription factor activity
SAZ_RS22480	COG0561	phosphatase activity
SAZ_RS22485	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SAZ_RS22495	COG2837	iron assimilation
SAZ_RS22500	COG2372	response to copper ion
SAZ_RS22580	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS22590	COG0006	proline dipeptidase activity
SAZ_RS22610	COG0653	protein targeting
SAZ_RS22625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAZ_RS22640	COG1846	Transcriptional regulator
SAZ_RS22645	COG0697	spore germination
SAZ_RS22665	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS22675	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS22685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SAZ_RS22690	COG1595	DNA-templated transcription, initiation
SAZ_RS22705	COG3437	response regulator, receiver
SAZ_RS22710	COG4999	Histidine kinase
SAZ_RS22710	COG3437	response regulator, receiver
SAZ_RS22710	COG2205	protein histidine kinase activity
SAZ_RS22710	COG3850	Histidine kinase
SAZ_RS22730	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS22735	COG5000	phosphorelay sensor kinase activity
SAZ_RS22785	COG2249	NAD(P)H dehydrogenase (quinone) activity
SAZ_RS22810	COG0745	RESPONSE REGULATOR receiver
SAZ_RS22815	COG2205	protein histidine kinase activity
SAZ_RS22825	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SAZ_RS22825	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SAZ_RS22830	COG0477	Major facilitator Superfamily
SAZ_RS22855	COG2353	YceI-like domain
SAZ_RS22860	COG2353	YceI-like domain
SAZ_RS22900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SAZ_RS22920	COG1191	sigma factor activity
SAZ_RS22925	COG1191	sigma factor activity
SAZ_RS22960	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS22965	COG0583	DNA-binding transcription factor activity
SAZ_RS22975	COG0590	tRNA wobble adenosine to inosine editing
SAZ_RS23020	COG0523	cobalamin synthesis protein
SAZ_RS23030	COG1064	alcohol dehydrogenase
SAZ_RS23055	COG2268	Band 7 protein
SAZ_RS23095	COG3209	COG3209 Rhs family protein
SAZ_RS23095	COG4104	PAAR repeat-containing protein
SAZ_RS23095	COG3209	COG3209 Rhs family protein
SAZ_RS23095	COG4104	PAAR repeat-containing protein
SAZ_RS23120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SAZ_RS23125	COG1834	amidinotransferase
SAZ_RS23135	COG2188	Transcriptional regulator
SAZ_RS23140	COG0477	Major facilitator Superfamily
SAZ_RS23150	COG0402	S-adenosylhomocysteine deaminase activity
SAZ_RS23170	COG1595	DNA-templated transcription, initiation
SAZ_RS23210	COG1132	(ABC) transporter
SAZ_RS23240	COG2188	Transcriptional regulator
SAZ_RS23280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAZ_RS23290	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
SAZ_RS23305	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SAZ_RS23390	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SAZ_RS23415	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SAZ_RS23420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SAZ_RS23440	COG1595	DNA-templated transcription, initiation
SAZ_RS23460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SAZ_RS23470	COG0339	signal peptide processing
SAZ_RS23475	COG2319	Wd-40 repeat
SAZ_RS23475	COG4249	Peptidase C14 caspase catalytic subunit p20
SAZ_RS23485	COG1408	metallophosphoesterase
SAZ_RS23495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAZ_RS23505	COG0003	Pfam Anion-transporting ATPase
SAZ_RS23525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAZ_RS23555	COG2267	carboxylic ester hydrolase activity
SAZ_RS23565	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SAZ_RS23570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAZ_RS23630	COG1111	helicase
SAZ_RS23630	COG1205	dead DEAH box helicase
SAZ_RS23635	COG1366	Belongs to the anti-sigma-factor antagonist family
SAZ_RS23645	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SAZ_RS23655	COG2890	protein-(glutamine-N5) methyltransferase activity
SAZ_RS23680	COG1754	DNA topoisomerase type I activity
SAZ_RS23680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SAZ_RS23685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SAZ_RS23690	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SAZ_RS23705	COG0584	glycerophosphoryl diester phosphodiesterase
SAZ_RS23710	COG3594	Acyltransferase
SAZ_RS23725	COG1349	DNA-binding transcription factor activity
SAZ_RS23735	COG1309	transcriptional regulator
SAZ_RS23740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAZ_RS23740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAZ_RS23780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SAZ_RS23780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SAZ_RS23790	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SAZ_RS23795	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SAZ_RS23800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SAZ_RS23805	COG0254	rRNA binding
SAZ_RS23815	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SAZ_RS23820	COG0640	Transcriptional regulator
SAZ_RS23845	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS23850	COG2318	DinB family
SAZ_RS23860	COG0076	glutamate decarboxylase activity
SAZ_RS23865	COG0655	NAD(P)H dehydrogenase (quinone) activity
SAZ_RS23875	COG0789	Transcriptional regulator
SAZ_RS23880	COG0393	Putative heavy-metal-binding
SAZ_RS23885	COG0586	Pfam SNARE associated Golgi protein
SAZ_RS23895	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SAZ_RS23900	COG2027	D-alanyl-D-alanine carboxypeptidase
SAZ_RS23910	COG0037	tRNA processing
SAZ_RS23925	COG0302	gtp cyclohydrolase
SAZ_RS23935	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SAZ_RS23935	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SAZ_RS23940	COG0302	gtp cyclohydrolase
SAZ_RS23950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SAZ_RS23950	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SAZ_RS23965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SAZ_RS23970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SAZ_RS23985	COG1174	glycine betaine transport
SAZ_RS23990	COG1174	glycine betaine transport
SAZ_RS23995	COG1732	Glycine betaine
SAZ_RS24005	COG0649	NAD binding
SAZ_RS24015	COG4585	Histidine kinase
SAZ_RS24030	COG0640	Transcriptional regulator
SAZ_RS24040	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
SAZ_RS24050	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SAZ_RS24055	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SAZ_RS24065	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SAZ_RS24085	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SAZ_RS24105	COG0739	heme binding
SAZ_RS24140	COG2205	protein histidine kinase activity
SAZ_RS24145	COG0745	RESPONSE REGULATOR receiver
SAZ_RS24155	COG1595	DNA-templated transcription, initiation
SAZ_RS24160	COG1194	a g-specific adenine glycosylase
SAZ_RS24170	COG0671	phosphoesterase, PA-phosphatase related
SAZ_RS24190	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SAZ_RS24210	COG0248	Ppx GppA phosphatase
SAZ_RS24215	COG1082	Xylose isomerase domain protein TIM barrel
SAZ_RS24220	COG0129	dihydroxy-acid dehydratase activity
SAZ_RS24250	COG1595	DNA-templated transcription, initiation
SAZ_RS24260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SAZ_RS24265	COG0180	Tryptophanyl-tRNA synthetase
SAZ_RS24315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAZ_RS24320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAZ_RS24330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAZ_RS24345	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS24390	COG0741	lytic transglycosylase activity
SAZ_RS24390	COG0739	heme binding
SAZ_RS24390	COG1196	nuclear chromosome segregation
SAZ_RS24395	COG0671	phosphoesterase, PA-phosphatase related
SAZ_RS24420	COG0494	nUDIX hydrolase
SAZ_RS24435	COG2188	Transcriptional regulator
SAZ_RS24440	COG0277	FAD linked oxidase domain protein
SAZ_RS24460	COG1937	Protein conserved in bacteria
SAZ_RS24470	COG0306	phosphate transporter
SAZ_RS24525	COG1595	DNA-templated transcription, initiation
SAZ_RS24530	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS24540	COG0754	glutathionylspermidine amidase activity
SAZ_RS24545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SAZ_RS24550	COG2890	protein-(glutamine-N5) methyltransferase activity
SAZ_RS24555	COG0667	Aldo Keto reductase
SAZ_RS24575	COG1733	regulation of RNA biosynthetic process
SAZ_RS24580	COG0431	NADPH-dependent FMN reductase
SAZ_RS24600	COG1490	D-aminoacyl-tRNA deacylase activity
SAZ_RS24605	COG0354	folic acid binding
SAZ_RS24620	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SAZ_RS24625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAZ_RS24630	COG3485	protocatechuate 3,4-dioxygenase
SAZ_RS24655	COG2897	thiosulfate sulfurtransferase activity
SAZ_RS24685	COG0745	RESPONSE REGULATOR receiver
SAZ_RS24690	COG1609	Transcriptional regulator
SAZ_RS24695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAZ_RS24700	COG0745	RESPONSE REGULATOR receiver
SAZ_RS24705	COG2205	protein histidine kinase activity
SAZ_RS24715	COG0737	Belongs to the 5'-nucleotidase family
SAZ_RS24720	COG0456	acetyltransferase
SAZ_RS24730	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SAZ_RS24740	COG0494	nUDIX hydrolase
SAZ_RS24740	COG0406	alpha-ribazole phosphatase activity
SAZ_RS24755	COG0438	transferase activity, transferring glycosyl groups
SAZ_RS24770	COG0588	phosphoglycerate mutase activity
SAZ_RS24775	COG0582	viral genome integration into host DNA
SAZ_RS24850	COG2186	Transcriptional regulator
SAZ_RS24865	COG5002	protein histidine kinase activity
SAZ_RS24880	COG1329	Transcriptional regulator
SAZ_RS24885	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SAZ_RS24890	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SAZ_RS24900	COG0215	cysteine-tRNA ligase activity
SAZ_RS24915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SAZ_RS24925	COG3842	ATPase activity
SAZ_RS24950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SAZ_RS24965	COG0667	Aldo Keto reductase
SAZ_RS25065	COG1228	amidohydrolase
SAZ_RS25070	COG1940	carbohydrate kinase activity
SAZ_RS25095	COG3336	cytochrome c oxidase
SAZ_RS25100	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SAZ_RS25105	COG0463	Glycosyl transferase, family 2
SAZ_RS25120	COG1278	Cold shock
SAZ_RS25145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAZ_RS25145	COG1263	PTS System
SAZ_RS25150	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SAZ_RS25195	COG3142	Participates in the control of copper homeostasis
SAZ_RS25205	COG3973	AAA domain
SAZ_RS25220	COG1061	Type III restriction enzyme res subunit
SAZ_RS25235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAZ_RS25240	COG1120	ATPase activity
SAZ_RS25245	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAZ_RS25250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAZ_RS25265	COG1278	Cold shock
SAZ_RS25270	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SAZ_RS25275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SAZ_RS25285	COG2814	Major facilitator Superfamily
SAZ_RS25330	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SAZ_RS25340	COG2252	PERMEase
SAZ_RS25365	COG0667	Aldo Keto reductase
SAZ_RS25390	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SAZ_RS25405	COG0247	lactate metabolic process
SAZ_RS25405	COG0277	FAD linked oxidase domain protein
SAZ_RS25415	COG0583	DNA-binding transcription factor activity
SAZ_RS25420	COG5006	permease, DMT superfamily
SAZ_RS25435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SAZ_RS25450	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS25470	COG0259	pyridoxamine-phosphate oxidase activity
SAZ_RS25480	COG4821	SIS domain
SAZ_RS25490	COG0596	Alpha beta hydrolase
SAZ_RS25490	COG2945	thiolester hydrolase activity
SAZ_RS25515	COG1131	(ABC) transporter
SAZ_RS25595	COG0515	serine threonine protein kinase
SAZ_RS25600	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS25625	COG0519	Catalyzes the synthesis of GMP from XMP
SAZ_RS25625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SAZ_RS25630	COG2084	Dehydrogenase
SAZ_RS25965	COG2815	serine threonine protein kinase
SAZ_RS25965	COG0515	serine threonine protein kinase
SAZ_RS25975	COG2197	response regulator
SAZ_RS26005	COG0739	heme binding
SAZ_RS26015	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SAZ_RS26030	COG0714	Associated with various cellular activities
SAZ_RS26040	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SAZ_RS26150	COG0045	succinate-CoA ligase (ADP-forming) activity
SAZ_RS26180	COG0138	bifunctional purine biosynthesis protein purh
SAZ_RS26195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SAZ_RS26205	COG0039	L-malate dehydrogenase activity
SAZ_RS26235	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS26245	COG4175	Glycine betaine
SAZ_RS26245	COG0517	IMP dehydrogenase activity
SAZ_RS26275	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SAZ_RS26320	COG1295	ribonuclease BN
SAZ_RS26330	COG0180	Tryptophanyl-tRNA synthetase
SAZ_RS26335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SAZ_RS26340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SAZ_RS26350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAZ_RS26355	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAZ_RS26360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAZ_RS26400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SAZ_RS26405	COG1053	succinate dehydrogenase
SAZ_RS26415	COG2009	succinate dehydrogenase
SAZ_RS26445	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SAZ_RS26445	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SAZ_RS26460	COG3265	gluconokinase activity
SAZ_RS26505	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAZ_RS26515	COG1216	Glycosyl transferase, family 2
SAZ_RS26530	COG2089	acid synthase
SAZ_RS26540	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SAZ_RS26540	COG1473	amidohydrolase
SAZ_RS26545	COG1744	ABC transporter substrate-binding protein PnrA-like
SAZ_RS26550	COG3845	ABC transporter
SAZ_RS26555	COG4603	Belongs to the binding-protein-dependent transport system permease family
SAZ_RS26560	COG1079	Belongs to the binding-protein-dependent transport system permease family
SAZ_RS26575	COG2814	Major facilitator Superfamily
SAZ_RS26580	COG0583	DNA-binding transcription factor activity
SAZ_RS26590	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SAZ_RS26615	COG2205	protein histidine kinase activity
SAZ_RS26620	COG0745	RESPONSE REGULATOR receiver
SAZ_RS26625	COG1595	DNA-templated transcription, initiation
SAZ_RS26640	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS26645	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS26650	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SAZ_RS26685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SAZ_RS26720	COG4770	biotin carboxylase activity
SAZ_RS26735	COG0424	maF-like protein
SAZ_RS26745	COG2365	Tyrosine phosphatase family
SAZ_RS26750	COG0768	penicillin binding
SAZ_RS26760	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SAZ_RS26770	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SAZ_RS26775	COG1024	Enoyl-CoA hydratase
SAZ_RS26785	COG2986	histidine ammonia-lyase
SAZ_RS26800	COG1376	ErfK ybiS ycfS ynhG family protein
SAZ_RS26815	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS26825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SAZ_RS26855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SAZ_RS26870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SAZ_RS26880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SAZ_RS26895	COG1331	Highly conserved protein containing a thioredoxin domain
SAZ_RS26900	COG0604	alcohol dehydrogenase
SAZ_RS26905	COG0154	amidase activity
SAZ_RS26910	COG0789	Transcriptional regulator
SAZ_RS26925	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SAZ_RS26940	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
SAZ_RS26955	COG1414	Transcriptional regulator
SAZ_RS26960	COG0251	oxidation-reduction process
SAZ_RS26965	COG2610	gluconate transmembrane transporter activity
SAZ_RS27065	COG0667	Aldo Keto reductase
SAZ_RS27070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SAZ_RS27075	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SAZ_RS27090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAZ_RS27095	COG0450	alkyl hydroperoxide reductase
SAZ_RS27145	COG1136	(ABC) transporter
SAZ_RS27155	COG1136	(ABC) transporter
SAZ_RS27170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAZ_RS27195	COG0114	fumarate hydratase activity
SAZ_RS27210	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SAZ_RS27210	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SAZ_RS27235	COG0778	Nitroreductase
SAZ_RS27240	COG1722	exodeoxyribonuclease VII activity
SAZ_RS27245	COG1570	exodeoxyribonuclease VII activity
SAZ_RS27250	COG1113	amino acid transport
SAZ_RS27255	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SAZ_RS27270	COG0012	GTP binding
SAZ_RS27295	COG0531	amino acid
SAZ_RS27320	COG0402	S-adenosylhomocysteine deaminase activity
SAZ_RS27335	COG1053	succinate dehydrogenase
SAZ_RS27355	COG1217	gtp-binding protein TYPA
SAZ_RS27360	COG4166	transmembrane transport
SAZ_RS27365	COG0601	transmembrane transport
SAZ_RS27370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAZ_RS27375	COG0444	Belongs to the ABC transporter superfamily
SAZ_RS27380	COG4608	Belongs to the ABC transporter superfamily
SAZ_RS27385	COG4608	Belongs to the ABC transporter superfamily
SAZ_RS27390	COG0444	Belongs to the ABC transporter superfamily
SAZ_RS27395	COG0601	transmembrane transport
SAZ_RS27400	COG4166	transmembrane transport
SAZ_RS27405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAZ_RS27425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SAZ_RS27445	COG1131	(ABC) transporter
SAZ_RS27455	COG4585	Histidine kinase
SAZ_RS27460	COG2197	response regulator
SAZ_RS27500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SAZ_RS27505	COG1611	Belongs to the LOG family
SAZ_RS27510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SAZ_RS27520	COG0519	Catalyzes the synthesis of GMP from XMP
SAZ_RS27525	COG1024	Enoyl-CoA hydratase
SAZ_RS27530	COG4122	O-methyltransferase activity
SAZ_RS27535	COG1595	DNA-templated transcription, initiation
SAZ_RS27545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAZ_RS27550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SAZ_RS27585	COG0598	Magnesium transport protein CorA
SAZ_RS27595	COG2814	Major facilitator Superfamily
SAZ_RS27610	COG2095	MarC family integral membrane protein
SAZ_RS27615	COG1432	Conserved Protein
SAZ_RS27665	COG4166	transmembrane transport
SAZ_RS27725	COG0210	DNA helicase
SAZ_RS27730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SAZ_RS27770	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SAZ_RS27815	COG3480	Lon protease (S16) C-terminal proteolytic domain
SAZ_RS27825	COG1615	UPF0182 protein
SAZ_RS27865	COG0753	catalase activity
SAZ_RS27875	COG0483	inositol monophosphate 1-phosphatase activity
SAZ_RS27885	COG2076	Multidrug Resistance protein
SAZ_RS27890	COG1162	GTPase activity
SAZ_RS27895	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SAZ_RS27905	COG2135	peptidase activity
SAZ_RS27915	COG1595	DNA-templated transcription, initiation
SAZ_RS27920	COG5662	AntiSigma factor
SAZ_RS27925	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SAZ_RS27925	COG2199	diguanylate cyclase activity
SAZ_RS27940	COG0242	peptide deformylase activity
SAZ_RS27945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAZ_RS27950	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAZ_RS27980	COG2188	Transcriptional regulator
SAZ_RS27985	COG2182	Extracellular solute-binding protein
SAZ_RS27990	COG1175	transmembrane transport
SAZ_RS27995	COG0395	ABC-type sugar transport system, permease component
SAZ_RS28000	COG1472	Belongs to the glycosyl hydrolase 3 family
SAZ_RS28005	COG0363	glucosamine-6-phosphate deaminase activity
SAZ_RS28010	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS28015	COG1309	transcriptional regulator
SAZ_RS28030	COG1597	lipid kinase activity
SAZ_RS28065	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SAZ_RS28080	COG2066	Belongs to the glutaminase family
SAZ_RS28095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SAZ_RS28110	COG0477	Major facilitator Superfamily
SAZ_RS28115	COG0598	Magnesium transport protein CorA
SAZ_RS28120	COG2807	transmembrane transport
SAZ_RS28125	COG2186	Transcriptional regulator
SAZ_RS28130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SAZ_RS28135	COG1993	acr, cog1993
SAZ_RS28140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SAZ_RS28170	COG4106	trans-aconitate 2-methyltransferase activity
SAZ_RS28175	COG1126	abc transporter atp-binding protein
SAZ_RS28180	COG0765	amino acid transport
SAZ_RS28185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAZ_RS28190	COG0281	malic enzyme
SAZ_RS28195	COG0604	alcohol dehydrogenase
SAZ_RS28230	COG0567	Dehydrogenase, E1 component
SAZ_RS28230	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAZ_RS28235	COG2205	protein histidine kinase activity
SAZ_RS28240	COG0745	RESPONSE REGULATOR receiver
SAZ_RS28255	COG1357	PFAM Pentapeptide repeats (8 copies)
SAZ_RS28260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SAZ_RS28345	COG1119	ATPase activity
SAZ_RS28355	COG0768	penicillin binding
SAZ_RS28365	COG2124	cytochrome p450
SAZ_RS28385	COG0018	arginyl-trna synthetase
SAZ_RS28390	COG0019	diaminopimelate decarboxylase activity
SAZ_RS28395	COG0460	homoserine dehydrogenase
SAZ_RS28400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SAZ_RS28405	COG0083	homoserine kinase activity
SAZ_RS28420	COG0254	rRNA binding
SAZ_RS28425	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SAZ_RS28430	COG2890	protein-(glutamine-N5) methyltransferase activity
SAZ_RS28440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SAZ_RS28445	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SAZ_RS28465	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SAZ_RS28470	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SAZ_RS28475	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SAZ_RS28480	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SAZ_RS28485	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SAZ_RS28490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SAZ_RS28495	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SAZ_RS28505	COG2124	cytochrome p450
SAZ_RS28515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS28515	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS28515	COG4221	oxidoreductase activity
SAZ_RS28515	COG3321	synthase
SAZ_RS28520	COG0300	oxidoreductase activity
SAZ_RS28520	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS28520	COG3321	synthase
SAZ_RS28520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS28520	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS28545	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS28545	COG3321	synthase
SAZ_RS28545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS28545	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS28545	COG0300	oxidoreductase activity
SAZ_RS28575	COG0534	Mate efflux family protein
SAZ_RS28585	COG2124	cytochrome p450
SAZ_RS28590	COG2124	cytochrome p450
SAZ_RS28605	COG3804	dihydrodipicolinate reductase
SAZ_RS28610	COG2197	response regulator
SAZ_RS28615	COG4585	Histidine kinase
SAZ_RS28630	COG1250	3-hydroxyacyl-CoA dehydrogenase
SAZ_RS28645	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SAZ_RS28680	COG1131	(ABC) transporter
SAZ_RS28700	COG0183	Belongs to the thiolase family
SAZ_RS28760	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SAZ_RS28760	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SAZ_RS28770	COG0745	RESPONSE REGULATOR receiver
SAZ_RS28775	COG0745	RESPONSE REGULATOR receiver
SAZ_RS28780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SAZ_RS28785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAZ_RS28820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SAZ_RS28825	COG0857	belongs to the CobB CobQ family
SAZ_RS28825	COG0280	phosphate acetyltransferase
SAZ_RS28830	COG0205	6-phosphofructokinase activity
SAZ_RS28835	COG1136	(ABC) transporter
SAZ_RS28835	COG0577	efflux transmembrane transporter activity
SAZ_RS28840	COG1136	(ABC) transporter
SAZ_RS28840	COG0577	efflux transmembrane transporter activity
SAZ_RS28850	COG4565	transcriptional regulatory protein
SAZ_RS28855	COG3290	protein histidine kinase activity
SAZ_RS28860	COG1301	dicarboxylic acid transport
SAZ_RS28865	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SAZ_RS28870	COG3281	Trehalose synthase
SAZ_RS28875	COG0366	Alpha amylase catalytic
SAZ_RS28880	COG0366	Alpha amylase catalytic
SAZ_RS28895	COG1132	(ABC) transporter
SAZ_RS28900	COG1132	(ABC) transporter
SAZ_RS28915	COG1376	ErfK ybiS ycfS ynhG family protein
SAZ_RS28935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SAZ_RS28935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SAZ_RS28940	COG0785	Cytochrome C biogenesis protein
SAZ_RS28950	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SAZ_RS28960	COG0438	transferase activity, transferring glycosyl groups
SAZ_RS28990	COG0671	phosphoesterase, PA-phosphatase related
SAZ_RS29015	COG1760	l-serine dehydratase
SAZ_RS29020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SAZ_RS29025	COG0509	glycine decarboxylation via glycine cleavage system
SAZ_RS29030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SAZ_RS29055	COG0747	negative chemotaxis
SAZ_RS29065	COG0444	Belongs to the ABC transporter superfamily
SAZ_RS29070	COG4608	Belongs to the ABC transporter superfamily
SAZ_RS29080	COG2860	membrane
SAZ_RS29100	COG0482	sulfurtransferase activity
SAZ_RS29110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SAZ_RS29120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SAZ_RS29130	COG4221	oxidoreductase activity
SAZ_RS29150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SAZ_RS29160	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SAZ_RS29165	COG0154	amidase activity
SAZ_RS29175	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SAZ_RS29185	COG0667	Aldo Keto reductase
SAZ_RS29205	COG3511	phospholipase C
SAZ_RS29210	COG2409	Drug exporters of the RND superfamily
SAZ_RS29225	COG1672	PFAM Archaeal ATPase
SAZ_RS29225	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SAZ_RS29235	COG2133	pyrroloquinoline quinone binding
SAZ_RS29240	COG0667	Aldo Keto reductase
SAZ_RS29250	COG3300	MHYT domain
SAZ_RS29250	COG5001	Diguanylate cyclase
SAZ_RS29260	COG0440	acetolactate synthase activity
SAZ_RS29265	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SAZ_RS29270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAZ_RS29290	COG3835	regulator
SAZ_RS29295	COG0506	proline dehydrogenase activity
SAZ_RS29300	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS29310	COG0473	3-isopropylmalate dehydrogenase activity
SAZ_RS29315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SAZ_RS29325	COG0832	Belongs to the urease beta subunit family
SAZ_RS29325	COG0831	urea catabolic process
SAZ_RS29330	COG0804	urea catabolic process
SAZ_RS29335	COG2957	Belongs to the agmatine deiminase family
SAZ_RS29340	COG1309	transcriptional regulator
SAZ_RS29345	COG0477	Major facilitator Superfamily
SAZ_RS29350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SAZ_RS29360	COG5492	domain, Protein
SAZ_RS29365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SAZ_RS29375	COG2814	Major facilitator Superfamily
SAZ_RS29380	COG2376	Dihydroxyacetone kinase
SAZ_RS29390	COG2376	Dihydroxyacetone kinase
SAZ_RS29405	COG2018	Roadblock/LC7 domain
SAZ_RS29415	COG2018	Roadblock/LC7 domain
SAZ_RS29435	COG2018	Roadblock/LC7 domain
SAZ_RS29450	COG0179	Fumarylacetoacetate (FAA) hydrolase
SAZ_RS29455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SAZ_RS29500	COG1414	Transcriptional regulator
SAZ_RS29505	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SAZ_RS29510	COG0066	3-isopropylmalate dehydratase activity
SAZ_RS29520	COG0776	regulation of translation
SAZ_RS29530	COG1920	GTP binding
SAZ_RS29540	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SAZ_RS29545	COG1181	Belongs to the D-alanine--D-alanine ligase family
SAZ_RS29565	COG0351	phosphomethylpyrimidine kinase
SAZ_RS29570	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SAZ_RS29575	COG1461	Dihydroxyacetone kinase
SAZ_RS29585	COG0742	ribosomal rna small subunit methyltransferase
SAZ_RS29590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SAZ_RS29605	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SAZ_RS29610	COG0571	ribonuclease III activity
SAZ_RS29615	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SAZ_RS29625	COG1254	Belongs to the acylphosphatase family
SAZ_RS29635	COG1196	nuclear chromosome segregation
SAZ_RS29640	COG0477	Major facilitator Superfamily
SAZ_RS29655	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SAZ_RS29690	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SAZ_RS29710	COG0228	four-way junction DNA binding
SAZ_RS29715	COG1837	Belongs to the UPF0109 family
SAZ_RS29720	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SAZ_RS29725	COG0336	Belongs to the RNA methyltransferase TrmD family
SAZ_RS29730	COG0335	large ribosomal subunit rRNA binding
SAZ_RS29745	COG0681	Belongs to the peptidase S26 family
SAZ_RS29750	COG0681	Belongs to the peptidase S26 family
SAZ_RS29765	COG4974	Belongs to the 'phage' integrase family
SAZ_RS29780	COG0792	nuclease activity
SAZ_RS29825	COG1191	sigma factor activity
SAZ_RS29835	COG0052	Belongs to the universal ribosomal protein uS2 family
SAZ_RS29840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SAZ_RS29845	COG0528	UMP kinase activity
SAZ_RS29850	COG0233	cytoplasmic translational termination
SAZ_RS29860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SAZ_RS29870	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SAZ_RS29875	COG3842	ATPase activity
SAZ_RS29880	COG2197	response regulator
SAZ_RS29885	COG4585	Histidine kinase
SAZ_RS29920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SAZ_RS29930	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS29945	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SAZ_RS29955	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS29965	COG3842	ATPase activity
SAZ_RS29970	COG1176	ABC-type spermidine putrescine transport system, permease component I
SAZ_RS29975	COG1177	transmembrane transport
SAZ_RS29980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SAZ_RS30015	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS30025	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SAZ_RS30030	COG0750	zinc metalloprotease
SAZ_RS30035	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SAZ_RS30050	COG0442	prolyl-tRNA aminoacylation
SAZ_RS30055	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SAZ_RS30070	COG0779	Required for maturation of 30S ribosomal subunits
SAZ_RS30085	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SAZ_RS30095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SAZ_RS30100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SAZ_RS30115	COG0455	bacterial-type flagellum organization
SAZ_RS30145	COG3266	domain, Protein
SAZ_RS30175	COG1404	Belongs to the peptidase S8 family
SAZ_RS30225	COG1674	ftsk spoiiie
SAZ_RS30235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SAZ_RS30240	COG1185	polyribonucleotide nucleotidyltransferase activity
SAZ_RS30245	COG0612	Peptidase, M16
SAZ_RS30250	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SAZ_RS30270	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SAZ_RS30275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SAZ_RS30280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SAZ_RS30330	COG3424	synthase
SAZ_RS30360	COG1799	cell septum assembly
SAZ_RS30390	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SAZ_RS30395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SAZ_RS30400	COG2235	arginine
SAZ_RS30405	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SAZ_RS30410	COG0531	amino acid
SAZ_RS30415	COG1024	Enoyl-CoA hydratase
SAZ_RS30445	COG0546	phosphoglycolate phosphatase activity
SAZ_RS30460	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS30470	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS30475	COG1024	Enoyl-CoA hydratase
SAZ_RS30490	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SAZ_RS30510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS30525	COG2175	clavaminate synthase activity
SAZ_RS30530	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS30580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SAZ_RS30585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SAZ_RS30600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAZ_RS30605	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS30630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SAZ_RS30650	COG0137	argininosuccinate synthase activity
SAZ_RS30655	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SAZ_RS30680	COG1653	transport
SAZ_RS30685	COG1175	transmembrane transport
SAZ_RS30690	COG0395	ABC-type sugar transport system, permease component
SAZ_RS30695	COG1940	carbohydrate kinase activity
SAZ_RS30700	COG4213	ABC transporter substrate-binding protein
SAZ_RS30710	COG4214	carbohydrate transport
SAZ_RS30715	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SAZ_RS30720	COG0531	amino acid
SAZ_RS30730	COG1024	Enoyl-CoA hydratase
SAZ_RS30730	COG1250	3-hydroxyacyl-CoA dehydrogenase
SAZ_RS30735	COG0183	Belongs to the thiolase family
SAZ_RS30745	COG0183	Belongs to the thiolase family
SAZ_RS30750	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SAZ_RS30765	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SAZ_RS30770	COG0446	pyridine nucleotide-disulphide oxidoreductase
SAZ_RS30780	COG0183	Belongs to the thiolase family
SAZ_RS30790	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SAZ_RS30795	COG3253	May function as heme-dependent peroxidase
SAZ_RS30820	COG1280	lysine exporter protein (LysE YggA)
SAZ_RS30830	COG1116	anion transmembrane transporter activity
SAZ_RS30865	COG0577	efflux transmembrane transporter activity
SAZ_RS30865	COG1136	(ABC) transporter
SAZ_RS30875	COG4585	Histidine kinase
SAZ_RS30880	COG2197	response regulator
SAZ_RS30885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SAZ_RS30890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SAZ_RS30905	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SAZ_RS30915	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SAZ_RS30920	COG0693	protein deglycase activity
SAZ_RS30925	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SAZ_RS31010	COG0584	glycerophosphoryl diester phosphodiesterase
SAZ_RS31060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SAZ_RS31065	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SAZ_RS31085	COG0529	Catalyzes the synthesis of activated sulfate
SAZ_RS31090	COG0175	sulfate reduction
SAZ_RS31095	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SAZ_RS31120	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS31130	COG3485	protocatechuate 3,4-dioxygenase
SAZ_RS31180	COG2080	2 iron, 2 sulfur cluster binding
SAZ_RS31185	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SAZ_RS31190	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SAZ_RS31200	COG3511	phospholipase C
SAZ_RS31205	COG0667	Aldo Keto reductase
SAZ_RS31215	COG1376	ErfK ybiS ycfS ynhG family protein
SAZ_RS31245	COG1131	(ABC) transporter
SAZ_RS31245	COG1716	ATPase activity
SAZ_RS31245	COG0842	Transport permease protein
SAZ_RS31250	COG2233	PERMEase
SAZ_RS31310	COG3290	protein histidine kinase activity
SAZ_RS31315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAZ_RS31315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAZ_RS31320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SAZ_RS31335	COG0640	Transcriptional regulator
SAZ_RS31340	COG0789	Transcriptional regulator
SAZ_RS31345	COG0789	Transcriptional regulator
SAZ_RS31350	COG1162	GTPase activity
SAZ_RS31365	COG0028	Belongs to the TPP enzyme family
SAZ_RS31385	COG1802	Transcriptional regulator
SAZ_RS31400	COG3835	regulator
SAZ_RS31415	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SAZ_RS31445	COG4552	Acetyltransferase involved in intracellular survival and related
SAZ_RS31460	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS31535	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS31545	COG2315	Protein conserved in bacteria
SAZ_RS31560	COG0753	catalase activity
SAZ_RS31565	COG0028	Belongs to the TPP enzyme family
SAZ_RS31570	COG2084	Dehydrogenase
SAZ_RS31575	COG3622	Belongs to the hyi family
SAZ_RS31580	COG3622	Belongs to the hyi family
SAZ_RS31600	COG2351	hydroxyisourate hydrolase activity
SAZ_RS31610	COG2233	PERMEase
SAZ_RS31620	COG2233	PERMEase
SAZ_RS31640	COG1288	antiporter activity
SAZ_RS31650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SAZ_RS31670	COG1414	Transcriptional regulator
SAZ_RS31680	COG1953	Uracil, thiamine, allantoin
SAZ_RS31685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SAZ_RS31690	COG4266	Belongs to the allantoicase family
SAZ_RS31720	COG0800	Aldolase
SAZ_RS31730	COG0583	DNA-binding transcription factor activity
SAZ_RS31740	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS31745	COG2188	Transcriptional regulator
SAZ_RS31755	COG1172	Belongs to the binding-protein-dependent transport system permease family
SAZ_RS31765	COG1940	carbohydrate kinase activity
SAZ_RS31790	COG1595	DNA-templated transcription, initiation
SAZ_RS31805	COG1335	isochorismatase
SAZ_RS31810	COG0477	Major facilitator Superfamily
SAZ_RS31845	COG0242	peptide deformylase activity
SAZ_RS31885	COG0640	Transcriptional regulator
SAZ_RS31915	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS31920	COG1959	2 iron, 2 sulfur cluster binding
SAZ_RS31930	COG4221	oxidoreductase activity
SAZ_RS31950	COG0596	Alpha beta hydrolase
SAZ_RS31970	COG1309	transcriptional regulator
SAZ_RS31980	COG0596	Alpha beta hydrolase
SAZ_RS32010	COG0179	Fumarylacetoacetate (FAA) hydrolase
SAZ_RS32085	COG0667	Aldo Keto reductase
SAZ_RS32130	COG0159	tryptophan synthase activity
SAZ_RS32210	COG0714	Associated with various cellular activities
SAZ_RS32365	COG1181	Belongs to the D-alanine--D-alanine ligase family
SAZ_RS32410	COG1484	DNA-dependent DNA replication
SAZ_RS32415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAZ_RS32505	COG0456	acetyltransferase
SAZ_RS32530	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SAZ_RS32615	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAZ_RS32645	COG2226	methyltransferase
SAZ_RS32650	COG2267	carboxylic ester hydrolase activity
SAZ_RS32655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAZ_RS32660	COG0435	Glutathione S-transferase
SAZ_RS32675	COG2409	Drug exporters of the RND superfamily
SAZ_RS32680	COG0387	Pfam Sodium calcium exchanger
SAZ_RS32690	COG0405	Gamma-glutamyltransferase
SAZ_RS32700	COG1335	isochorismatase
SAZ_RS32705	COG0477	Major facilitator Superfamily
SAZ_RS32720	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SAZ_RS32740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SAZ_RS32745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS32770	COG0095	Lipoate-protein ligase
SAZ_RS32775	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SAZ_RS32790	COG0483	inositol monophosphate 1-phosphatase activity
SAZ_RS32800	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SAZ_RS32815	COG1309	transcriptional regulator
SAZ_RS32830	COG0494	nUDIX hydrolase
SAZ_RS32835	COG1929	Belongs to the glycerate kinase type-1 family
SAZ_RS32845	COG0688	phosphatidylethanolamine metabolic process
SAZ_RS32850	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS32860	COG2301	Belongs to the HpcH HpaI aldolase family
SAZ_RS32865	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SAZ_RS32865	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SAZ_RS32880	COG1250	3-hydroxyacyl-CoA dehydrogenase
SAZ_RS32910	COG0789	Transcriptional regulator
SAZ_RS32940	COG0366	Alpha amylase catalytic
SAZ_RS32950	COG2362	D-Aminopeptidase
SAZ_RS32955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SAZ_RS32970	COG2124	cytochrome p450
SAZ_RS32985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SAZ_RS33005	COG0010	Belongs to the arginase family
SAZ_RS33010	COG0457	Tetratricopeptide repeat
SAZ_RS33030	COG1597	lipid kinase activity
SAZ_RS33055	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SAZ_RS33075	COG0531	amino acid
SAZ_RS33100	COG2154	pterin-4-alpha-carbinolamine dehydratase
SAZ_RS33115	COG2890	protein-(glutamine-N5) methyltransferase activity
SAZ_RS33140	COG0656	L-ascorbic acid biosynthetic process
SAZ_RS33150	COG0583	DNA-binding transcription factor activity
SAZ_RS33170	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SAZ_RS33180	COG0287	Prephenate dehydrogenase
SAZ_RS33180	COG1605	Chorismate mutase
SAZ_RS33200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SAZ_RS33210	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS33325	COG1674	ftsk spoiiie
SAZ_RS33365	COG2255	four-way junction helicase activity
SAZ_RS33475	COG3328	transposase activity
SAZ_RS33490	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SAZ_RS33495	COG0582	viral genome integration into host DNA
SAZ_RS33520	COG1132	(ABC) transporter
SAZ_RS33545	COG2197	response regulator
SAZ_RS33580	COG0577	efflux transmembrane transporter activity
SAZ_RS33580	COG1136	(ABC) transporter
SAZ_RS33585	COG1136	(ABC) transporter
SAZ_RS33600	COG0745	RESPONSE REGULATOR receiver
SAZ_RS33605	COG2205	protein histidine kinase activity
SAZ_RS33615	COG0702	epimerase
SAZ_RS33620	COG0477	Major facilitator Superfamily
SAZ_RS33630	COG0745	RESPONSE REGULATOR receiver
SAZ_RS33655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAZ_RS33680	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS33685	COG0477	Major facilitator Superfamily
SAZ_RS33695	COG0431	NADPH-dependent FMN reductase
SAZ_RS33700	COG0667	Aldo Keto reductase
SAZ_RS33750	COG2124	cytochrome p450
SAZ_RS33755	COG1819	glycosyl
SAZ_RS33765	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
SAZ_RS33790	COG2192	nodulation
SAZ_RS33820	COG5002	protein histidine kinase activity
SAZ_RS33835	COG0697	spore germination
SAZ_RS33860	COG1522	sequence-specific DNA binding
SAZ_RS33880	COG1063	alcohol dehydrogenase
SAZ_RS33895	COG4585	Histidine kinase
SAZ_RS33900	COG2197	response regulator
SAZ_RS33905	COG2340	Cysteine-rich secretory protein family
SAZ_RS33920	COG0640	Transcriptional regulator
SAZ_RS33940	COG3629	intracellular signal transduction
SAZ_RS33940	COG3903	Transcriptional regulator
SAZ_RS33945	COG0720	synthase
SAZ_RS33955	COG0302	gtp cyclohydrolase
SAZ_RS33960	COG0516	GMP reductase activity
SAZ_RS33960	COG0517	IMP dehydrogenase activity
SAZ_RS33965	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SAZ_RS33970	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SAZ_RS33985	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SAZ_RS34005	COG0647	UMP catabolic process
SAZ_RS34040	COG0717	Belongs to the dCTP deaminase family
SAZ_RS34045	COG0475	glutathione-regulated potassium exporter activity
SAZ_RS34055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SAZ_RS34060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SAZ_RS34070	COG1834	amidinotransferase
SAZ_RS34100	COG0583	DNA-binding transcription factor activity
SAZ_RS34105	COG1846	Transcriptional regulator
SAZ_RS34125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAZ_RS34130	COG1846	Transcriptional regulator
SAZ_RS34140	COG1309	transcriptional regulator
SAZ_RS34165	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SAZ_RS34175	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS34190	COG1136	(ABC) transporter
SAZ_RS34250	COG2205	protein histidine kinase activity
SAZ_RS34255	COG0745	RESPONSE REGULATOR receiver
SAZ_RS34280	COG3226	Transcriptional regulator
SAZ_RS34290	COG1846	Transcriptional regulator
SAZ_RS34300	COG1309	transcriptional regulator
SAZ_RS34310	COG1309	transcriptional regulator
SAZ_RS34315	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS34320	COG1349	DNA-binding transcription factor activity
SAZ_RS34330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SAZ_RS34335	COG2814	Major facilitator Superfamily
SAZ_RS34345	COG1515	deoxyribonuclease V activity
SAZ_RS34350	COG3268	Saccharopine dehydrogenase
SAZ_RS34360	COG1285	pathogenesis
SAZ_RS34365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SAZ_RS34375	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS34380	COG0183	Belongs to the thiolase family
SAZ_RS34385	COG1024	Enoyl-CoA hydratase
SAZ_RS34385	COG1250	3-hydroxyacyl-CoA dehydrogenase
SAZ_RS34400	COG1113	amino acid transport
SAZ_RS34410	COG3568	Endonuclease Exonuclease Phosphatase
SAZ_RS34460	COG2936	dipeptidyl-peptidase activity
SAZ_RS34485	COG2183	response to ionizing radiation
SAZ_RS34495	COG4977	sequence-specific DNA binding
SAZ_RS34530	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SAZ_RS34570	COG1134	teichoic acid transport
SAZ_RS34575	COG1562	ergosterol biosynthetic process
SAZ_RS34585	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SAZ_RS34595	COG1657	PFAM Prenyltransferase squalene oxidase
SAZ_RS34615	COG2365	Tyrosine phosphatase family
SAZ_RS34620	COG2755	lipolytic protein G-D-S-L family
SAZ_RS34680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAZ_RS34700	COG2018	Roadblock/LC7 domain
SAZ_RS34725	COG1228	amidohydrolase
SAZ_RS34730	COG2267	carboxylic ester hydrolase activity
SAZ_RS34760	COG2124	cytochrome p450
SAZ_RS34765	COG1686	Belongs to the peptidase S11 family
SAZ_RS34795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAZ_RS34810	COG1250	3-hydroxyacyl-CoA dehydrogenase
SAZ_RS34815	COG3246	L-lysine catabolic process to acetate
SAZ_RS34830	COG0174	glutamine synthetase
SAZ_RS34840	COG0477	Major facilitator Superfamily
SAZ_RS34850	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS34880	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS34890	COG1652	LysM domain
SAZ_RS34895	COG1113	amino acid transport
SAZ_RS34900	COG2706	6-phosphogluconolactonase activity
SAZ_RS34935	COG0698	ribose 5-phosphate isomerase
SAZ_RS34940	COG0149	triose-phosphate isomerase activity
SAZ_RS34995	COG3537	Alpha-1,2-mannosidase
SAZ_RS35010	COG0531	amino acid
SAZ_RS35015	COG3360	Dodecin
SAZ_RS35075	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SAZ_RS35080	COG0121	glutamine amidotransferase
SAZ_RS35085	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SAZ_RS35090	COG3572	ergothioneine biosynthetic process
SAZ_RS35125	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS35130	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS35160	COG0601	transmembrane transport
SAZ_RS35165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAZ_RS35170	COG0444	Belongs to the ABC transporter superfamily
SAZ_RS35185	COG1349	DNA-binding transcription factor activity
SAZ_RS35190	COG2814	Major facilitator Superfamily
SAZ_RS35200	COG1070	Carbohydrate kinase
SAZ_RS35205	COG0588	phosphoglycerate mutase activity
SAZ_RS35210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAZ_RS35215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SAZ_RS35215	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SAZ_RS35240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAZ_RS35240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAZ_RS35245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAZ_RS35250	COG1070	Carbohydrate kinase
SAZ_RS35255	COG3458	cephalosporin-C deacetylase activity
SAZ_RS35270	COG0765	amino acid transport
SAZ_RS35280	COG2040	homocysteine
SAZ_RS35295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SAZ_RS35300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SAZ_RS35345	COG2018	Roadblock/LC7 domain
SAZ_RS35370	COG1946	Acyl-CoA thioesterase
SAZ_RS35385	COG1132	(ABC) transporter
SAZ_RS35390	COG1132	(ABC) transporter
SAZ_RS35400	COG1301	dicarboxylic acid transport
SAZ_RS35425	COG1132	(ABC) transporter
SAZ_RS35435	COG1556	Lactate utilization protein
SAZ_RS35440	COG1139	Iron-sulfur cluster binding protein
SAZ_RS35450	COG0477	Major facilitator Superfamily
SAZ_RS35460	COG0492	ferredoxin-NADP+ reductase activity
SAZ_RS35475	COG1116	anion transmembrane transporter activity
SAZ_RS35480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SAZ_RS35485	COG0432	Pfam Uncharacterised protein family UPF0047
SAZ_RS35490	COG2124	cytochrome p450
SAZ_RS35505	COG2304	oxidoreductase activity
SAZ_RS35525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SAZ_RS35555	COG1309	transcriptional regulator
SAZ_RS35580	COG2124	cytochrome p450
SAZ_RS35585	COG1309	transcriptional regulator
SAZ_RS35625	COG4213	ABC transporter substrate-binding protein
SAZ_RS35665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SAZ_RS35670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SAZ_RS35690	COG1595	DNA-templated transcription, initiation
SAZ_RS35700	COG2706	6-phosphogluconolactonase activity
SAZ_RS35725	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SAZ_RS35735	COG1902	pentaerythritol trinitrate reductase activity
SAZ_RS35770	COG2197	response regulator
SAZ_RS35775	COG0366	Alpha amylase catalytic
SAZ_RS35780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAZ_RS35795	COG2345	Transcriptional regulator
SAZ_RS35825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SAZ_RS35840	COG1285	pathogenesis
SAZ_RS35880	COG0477	Major facilitator Superfamily
SAZ_RS35885	COG1957	nucleoside hydrolase
SAZ_RS35890	COG1609	Transcriptional regulator
SAZ_RS35910	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SAZ_RS35930	COG1796	DNA polymerase
SAZ_RS35930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SAZ_RS35955	COG0488	(ABC) transporter
SAZ_RS35960	COG0488	(ABC) transporter
SAZ_RS35975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SAZ_RS35985	COG2197	response regulator
SAZ_RS35990	COG4585	Histidine kinase
SAZ_RS36000	COG0596	Alpha beta hydrolase
SAZ_RS36005	COG0805	protein transport
SAZ_RS36075	COG2205	protein histidine kinase activity
SAZ_RS36080	COG0745	RESPONSE REGULATOR receiver
SAZ_RS36090	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SAZ_RS36090	COG3291	Pkd domain containing protein
SAZ_RS36145	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS36165	COG1309	transcriptional regulator
SAZ_RS36175	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS36180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SAZ_RS36205	COG1228	amidohydrolase
SAZ_RS36215	COG0463	Glycosyl transferase, family 2
SAZ_RS36230	COG2270	Major facilitator Superfamily
SAZ_RS36260	COG3012	SEC-C Motif Domain Protein
SAZ_RS36270	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SAZ_RS36275	COG3285	dna ligase
SAZ_RS36275	COG1793	dna ligase
SAZ_RS36280	COG1686	Belongs to the peptidase S11 family
SAZ_RS36285	COG1278	Cold shock
SAZ_RS36320	COG0395	ABC-type sugar transport system, permease component
SAZ_RS36325	COG1175	transmembrane transport
SAZ_RS36335	COG1609	Transcriptional regulator
SAZ_RS36350	COG4585	Histidine kinase
SAZ_RS36355	COG2197	response regulator
SAZ_RS36360	COG0739	heme binding
SAZ_RS36390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SAZ_RS36400	COG1846	Transcriptional regulator
SAZ_RS36405	COG1764	response to oxidative stress
SAZ_RS36445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SAZ_RS36515	COG2124	cytochrome p450
SAZ_RS36520	COG1024	Enoyl-CoA hydratase
SAZ_RS36520	COG1250	3-hydroxyacyl-CoA dehydrogenase
SAZ_RS36530	COG0110	maltose O-acetyltransferase activity
SAZ_RS36545	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SAZ_RS36555	COG1832	CoA-binding protein
SAZ_RS36570	COG1739	Uncharacterized protein family UPF0029
SAZ_RS36575	COG0531	amino acid
SAZ_RS36595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAZ_RS36630	COG0584	glycerophosphoryl diester phosphodiesterase
SAZ_RS36635	COG0420	3'-5' exonuclease activity
SAZ_RS36645	COG1522	sequence-specific DNA binding
SAZ_RS36670	COG0346	lactoylglutathione lyase activity
SAZ_RS36680	COG2188	Transcriptional regulator
SAZ_RS36685	COG1940	carbohydrate kinase activity
SAZ_RS36700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SAZ_RS36710	COG1309	transcriptional regulator
SAZ_RS36730	COG0456	acetyltransferase
SAZ_RS36745	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS36785	COG0583	DNA-binding transcription factor activity
SAZ_RS36800	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SAZ_RS36805	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SAZ_RS36810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SAZ_RS36815	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SAZ_RS36840	COG0740	serine-type endopeptidase activity
SAZ_RS36865	COG0038	chloride channel
SAZ_RS36900	COG1136	(ABC) transporter
SAZ_RS37025	COG0831	urea catabolic process
SAZ_RS37030	COG0832	Belongs to the urease beta subunit family
SAZ_RS37035	COG0804	urea catabolic process
SAZ_RS37045	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SAZ_RS37050	COG0829	nickel cation binding
SAZ_RS37100	COG0205	6-phosphofructokinase activity
SAZ_RS37105	COG3442	glutamine amidotransferase
SAZ_RS37115	COG0242	peptide deformylase activity
SAZ_RS37125	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS37175	COG1215	transferase activity, transferring glycosyl groups
SAZ_RS37185	COG0745	RESPONSE REGULATOR receiver
SAZ_RS37190	COG2205	protein histidine kinase activity
SAZ_RS37195	COG3960	tartronate-semialdehyde synthase activity
SAZ_RS37200	COG3622	Belongs to the hyi family
SAZ_RS37205	COG2084	Dehydrogenase
SAZ_RS37210	COG2205	protein histidine kinase activity
SAZ_RS37220	COG2124	cytochrome p450
SAZ_RS37240	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS37255	COG0477	Major facilitator Superfamily
SAZ_RS37270	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SAZ_RS37300	COG0375	protein maturation
SAZ_RS37305	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SAZ_RS37310	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SAZ_RS37315	COG0298	carbon dioxide binding
SAZ_RS37325	COG0309	Hydrogenase expression formation protein (HypE)
SAZ_RS37350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SAZ_RS37360	COG2837	iron assimilation
SAZ_RS37370	COG0640	Transcriptional regulator
SAZ_RS37375	COG0531	amino acid
SAZ_RS37390	COG1793	dna ligase
SAZ_RS37410	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS37430	COG3290	protein histidine kinase activity
SAZ_RS37435	COG1349	DNA-binding transcription factor activity
SAZ_RS37440	COG3395	kinase activity
SAZ_RS37450	COG3395	kinase activity
SAZ_RS37455	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SAZ_RS37505	COG1131	(ABC) transporter
SAZ_RS37540	COG2814	Major facilitator Superfamily
SAZ_RS37560	COG3118	belongs to the thioredoxin family
SAZ_RS37590	COG2233	PERMEase
SAZ_RS37615	COG0657	acetylesterase activity
SAZ_RS37625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS37640	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS37645	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS37650	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS37655	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS37660	COG1024	Enoyl-CoA hydratase
SAZ_RS37665	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS37675	COG1309	transcriptional regulator
SAZ_RS37680	COG0183	Belongs to the thiolase family
SAZ_RS37685	COG2365	Tyrosine phosphatase family
SAZ_RS37705	COG1024	Enoyl-CoA hydratase
SAZ_RS37715	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS37720	COG3971	2-oxopent-4-enoate hydratase activity
SAZ_RS37755	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS37760	COG2267	carboxylic ester hydrolase activity
SAZ_RS37770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAZ_RS37775	COG2030	dehydratase
SAZ_RS37780	COG1053	succinate dehydrogenase
SAZ_RS37815	COG0596	Alpha beta hydrolase
SAZ_RS37815	COG2945	thiolester hydrolase activity
SAZ_RS37830	COG3511	phospholipase C
SAZ_RS37865	COG1181	Belongs to the D-alanine--D-alanine ligase family
SAZ_RS37870	COG0477	Major facilitator Superfamily
SAZ_RS37875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS37900	COG1509	lysine 2,3-aminomutase activity
SAZ_RS37905	COG0436	Aminotransferase
SAZ_RS37920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAZ_RS37980	COG2261	transglycosylase associated protein
SAZ_RS38000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SAZ_RS38010	COG1316	TRANSCRIPTIONal
SAZ_RS38020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SAZ_RS38025	COG0640	Transcriptional regulator
SAZ_RS38075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SAZ_RS38080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SAZ_RS38100	COG2837	iron assimilation
SAZ_RS38125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SAZ_RS38130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SAZ_RS38135	COG1116	anion transmembrane transporter activity
SAZ_RS38140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SAZ_RS38150	COG0596	Alpha beta hydrolase
SAZ_RS38175	COG0596	Alpha beta hydrolase
SAZ_RS38185	COG1657	PFAM Prenyltransferase squalene oxidase
SAZ_RS38190	COG2124	cytochrome p450
SAZ_RS38240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAZ_RS38245	COG1120	ATPase activity
SAZ_RS38270	COG0515	serine threonine protein kinase
SAZ_RS38280	COG1132	(ABC) transporter
SAZ_RS38285	COG1132	(ABC) transporter
SAZ_RS38290	COG2197	response regulator
SAZ_RS38310	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SAZ_RS38310	COG0515	serine threonine protein kinase
SAZ_RS38320	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SAZ_RS38320	COG0515	serine threonine protein kinase
SAZ_RS38330	COG0583	DNA-binding transcription factor activity
SAZ_RS38350	COG1595	DNA-templated transcription, initiation
SAZ_RS38395	COG0167	dihydroorotate dehydrogenase activity
SAZ_RS38405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAZ_RS38410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SAZ_RS38430	COG1021	2,3-dihydroxybenzoate-AMP ligase
SAZ_RS38435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS38450	COG0488	(ABC) transporter
SAZ_RS38465	COG1309	transcriptional regulator
SAZ_RS38470	COG0154	amidase activity
SAZ_RS38475	COG3321	synthase
SAZ_RS38475	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS38475	COG0604	alcohol dehydrogenase
SAZ_RS38485	COG1132	(ABC) transporter
SAZ_RS38500	COG3226	Transcriptional regulator
SAZ_RS38505	COG0154	amidase activity
SAZ_RS38515	COG1733	regulation of RNA biosynthetic process
SAZ_RS38535	COG0477	Major facilitator Superfamily
SAZ_RS38565	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
SAZ_RS38580	COG1309	transcriptional regulator
SAZ_RS38590	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SAZ_RS38600	COG1410	methionine synthase
SAZ_RS38600	COG0646	methionine synthase
SAZ_RS38605	COG0646	methionine synthase
SAZ_RS38605	COG1410	methionine synthase
SAZ_RS38610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAZ_RS38615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SAZ_RS38620	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS38630	COG2197	response regulator
SAZ_RS38635	COG0066	3-isopropylmalate dehydratase activity
SAZ_RS38640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SAZ_RS38645	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SAZ_RS38650	COG0473	3-isopropylmalate dehydrogenase activity
SAZ_RS38655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SAZ_RS38665	COG1309	transcriptional regulator
SAZ_RS38680	COG0477	Major facilitator Superfamily
SAZ_RS38695	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SAZ_RS38700	COG1692	metallophosphoesterase
SAZ_RS38705	COG0475	glutathione-regulated potassium exporter activity
SAZ_RS38710	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS38715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAZ_RS38720	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SAZ_RS38725	COG0129	dihydroxy-acid dehydratase activity
SAZ_RS38755	COG3629	intracellular signal transduction
SAZ_RS38755	COG3903	Transcriptional regulator
SAZ_RS38780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAZ_RS38790	COG2267	carboxylic ester hydrolase activity
SAZ_RS38800	COG1063	alcohol dehydrogenase
SAZ_RS38810	COG1051	belongs to the nudix hydrolase family
SAZ_RS38850	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS38875	COG3634	alkyl hydroperoxide reductase activity
SAZ_RS38885	COG0702	epimerase
SAZ_RS38895	COG2045	Belongs to the ComB family
SAZ_RS38910	COG1960	acyl-CoA dehydrogenase activity
SAZ_RS38920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SAZ_RS38925	COG0583	DNA-binding transcription factor activity
SAZ_RS38965	COG2268	Band 7 protein
SAZ_RS38970	COG1585	Membrane protein implicated in regulation of membrane protease activity
SAZ_RS38980	COG0672	)-iron permease
SAZ_RS39065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SAZ_RS39080	COG2249	NAD(P)H dehydrogenase (quinone) activity
SAZ_RS39085	COG0640	Transcriptional regulator
SAZ_RS39095	COG2197	response regulator
SAZ_RS39100	COG4585	Histidine kinase
SAZ_RS39110	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SAZ_RS39115	COG0443	Heat shock 70 kDa protein
SAZ_RS39120	COG0443	Heat shock 70 kDa protein
SAZ_RS39155	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SAZ_RS39155	COG0517	IMP dehydrogenase activity
SAZ_RS39190	COG0640	Transcriptional regulator
SAZ_RS39195	COG0463	Glycosyl transferase, family 2
SAZ_RS39200	COG0488	(ABC) transporter
SAZ_RS39220	COG0367	asparagine synthase
SAZ_RS39230	COG2423	ornithine cyclodeaminase activity
SAZ_RS39235	COG3469	chitinase activity
SAZ_RS39245	COG0009	L-threonylcarbamoyladenylate synthase
SAZ_RS39265	COG2378	regulation of single-species biofilm formation
SAZ_RS39270	COG1070	Carbohydrate kinase
SAZ_RS39275	COG1063	alcohol dehydrogenase
SAZ_RS39285	COG2124	cytochrome p450
SAZ_RS39300	COG0702	epimerase
SAZ_RS39310	COG1191	sigma factor activity
SAZ_RS39370	COG2132	Multicopper oxidase
SAZ_RS39390	COG2226	methyltransferase
SAZ_RS39415	COG1175	transmembrane transport
SAZ_RS39420	COG0395	ABC-type sugar transport system, permease component
SAZ_RS39440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SAZ_RS39485	COG0477	Major facilitator Superfamily
SAZ_RS39575	COG2205	protein histidine kinase activity
SAZ_RS39650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAZ_RS39665	COG0747	negative chemotaxis
SAZ_RS39685	COG1464	Belongs to the NlpA lipoprotein family
SAZ_RS39695	COG2011	ABC-type metal ion transport system permease component
SAZ_RS39720	COG0504	CTP synthase activity
SAZ_RS39745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SAZ_RS39780	COG3046	protein related to deoxyribodipyrimidine photolyase
SAZ_RS39795	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS39800	COG1556	Lactate utilization protein
SAZ_RS39805	COG1139	Iron-sulfur cluster binding protein
SAZ_RS39810	COG0247	lactate metabolic process
SAZ_RS39825	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS39850	COG2957	Belongs to the agmatine deiminase family
SAZ_RS39860	COG4608	Belongs to the ABC transporter superfamily
SAZ_RS39865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAZ_RS39875	COG0747	negative chemotaxis
SAZ_RS39880	COG2957	Belongs to the agmatine deiminase family
SAZ_RS39885	COG0515	serine threonine protein kinase
SAZ_RS39885	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SAZ_RS39905	COG2957	Belongs to the agmatine deiminase family
SAZ_RS39910	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SAZ_RS39980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SAZ_RS39985	COG0697	spore germination
SAZ_RS39995	COG4257	antibiotic catabolic process
SAZ_RS40025	COG3938	Belongs to the proline racemase family
SAZ_RS40060	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SAZ_RS40105	COG0604	alcohol dehydrogenase
SAZ_RS40105	COG3321	synthase
SAZ_RS40135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SAZ_RS40145	COG3321	synthase
SAZ_RS40145	COG0604	alcohol dehydrogenase
SAZ_RS40155	COG3321	synthase
SAZ_RS40155	COG0604	alcohol dehydrogenase
SAZ_RS40160	COG3321	synthase
SAZ_RS40160	COG0604	alcohol dehydrogenase
SAZ_RS40175	COG0604	alcohol dehydrogenase
SAZ_RS40175	COG3321	synthase
SAZ_RS40190	COG2197	response regulator
SAZ_RS40215	COG1473	amidohydrolase
SAZ_RS40230	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SAZ_RS40245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SAZ_RS40265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS40295	COG1012	belongs to the aldehyde dehydrogenase family
SAZ_RS40300	COG1063	alcohol dehydrogenase
SAZ_RS40305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SAZ_RS40315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SAZ_RS40335	COG1140	nitrate reductase beta subunit
SAZ_RS40400	COG4948	Mandelate Racemase Muconate Lactonizing
SAZ_RS40475	COG2345	Transcriptional regulator
SAZ_RS40490	COG0673	inositol 2-dehydrogenase activity
SAZ_RS40545	COG0702	epimerase
SAZ_RS40565	COG1132	(ABC) transporter
SAZ_RS40625	COG0745	RESPONSE REGULATOR receiver
SAZ_RS40630	COG5002	protein histidine kinase activity
SAZ_RS40675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SAZ_RS40685	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SAZ_RS40690	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SAZ_RS40700	COG0318	PFAM AMP-dependent synthetase and ligase
SAZ_RS40710	COG1250	3-hydroxyacyl-CoA dehydrogenase
SAZ_RS40740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SAZ_RS40740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SAZ_RS40760	COG0596	Alpha beta hydrolase
SAZ_RS40765	COG1309	transcriptional regulator
SAZ_RS40775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAZ_RS40780	COG0515	serine threonine protein kinase
SAZ_RS40780	COG2815	serine threonine protein kinase
SAZ_RS40790	COG3795	YCII-related domain
SAZ_RS40795	COG4941	Belongs to the sigma-70 factor family
SAZ_RS40800	COG1021	2,3-dihydroxybenzoate-AMP ligase
SAZ_RS40805	COG2272	Belongs to the type-B carboxylesterase lipase family
SAZ_RS40815	COG2814	Major facilitator Superfamily
SAZ_RS40820	COG3979	chitinase
SAZ_RS40940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SAZ_RS40960	COG2197	response regulator
SAZ_RS40970	COG1136	(ABC) transporter
SAZ_RS40970	COG0577	efflux transmembrane transporter activity
SAZ_RS40995	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS40995	COG0604	alcohol dehydrogenase
SAZ_RS40995	COG3321	synthase
SAZ_RS41005	COG0666	response to abiotic stimulus
SAZ_RS41020	COG2208	phosphoserine phosphatase activity
SAZ_RS41020	COG2770	Histidine kinase
SAZ_RS41105	COG1733	regulation of RNA biosynthetic process
SAZ_RS41110	COG0702	epimerase
SAZ_RS41135	COG0300	oxidoreductase activity
SAZ_RS41170	COG0431	NADPH-dependent FMN reductase
SAZ_RS41180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAZ_RS41220	COG1053	succinate dehydrogenase
SAZ_RS41275	COG1309	transcriptional regulator
SAZ_RS41325	COG4977	sequence-specific DNA binding
SAZ_RS41410	COG1132	(ABC) transporter
SAZ_RS41450	COG0604	alcohol dehydrogenase
SAZ_RS41450	COG3321	synthase
SAZ_RS41450	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS41455	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SAZ_RS41460	COG2801	Transposase and inactivated derivatives
SAZ_RS41465	COG2963	transposase activity
SAZ_RS41490	COG3328	transposase activity
SAZ_RS41590	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SAZ_RS41800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS41815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS41820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS41825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS41875	COG0420	3'-5' exonuclease activity
SAZ_RS41880	COG0419	ATPase involved in DNA repair
SAZ_RS41960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS41965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS41965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS41970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS41990	COG3118	belongs to the thioredoxin family
SAZ_RS42025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SAZ_RS42035	COG2188	Transcriptional regulator
SAZ_RS42060	COG3850	Histidine kinase
SAZ_RS42145	COG1674	ftsk spoiiie
SAZ_RS42160	COG2226	methyltransferase
SAZ_RS42165	COG2186	Transcriptional regulator
SAZ_RS42170	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SAZ_RS42170	COG0515	serine threonine protein kinase
SAZ_RS42180	COG0488	(ABC) transporter
SAZ_RS42260	COG0494	nUDIX hydrolase
SAZ_RS42275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SAZ_RS42280	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SAZ_RS42290	COG0582	viral genome integration into host DNA
SAZ_RS42320	COG4221	oxidoreductase activity
SAZ_RS42320	COG3321	synthase
SAZ_RS42320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAZ_RS42320	COG0300	oxidoreductase activity
SAZ_RS42330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS42330	COG3321	synthase
SAZ_RS42330	COG1028	Short-chain dehydrogenase reductase Sdr
SAZ_RS42330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SAZ_RS42330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAZ_RS42380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SAZ_RS42395	COG2340	Cysteine-rich secretory protein family
SAZ_RS42405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAZ_RS42420	COG2815	serine threonine protein kinase
SAZ_RS42420	COG0515	serine threonine protein kinase
SAZ_RS42430	COG0419	ATPase involved in DNA repair
SAZ_RS42510	COG3321	synthase
SAZ_RS42510	COG0604	alcohol dehydrogenase
SAZ_RS42535	COG0604	alcohol dehydrogenase
SAZ_RS42535	COG3321	synthase
SAZ_RS42540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS42550	COG0655	NAD(P)H dehydrogenase (quinone) activity
SAZ_RS42605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS42610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS42610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SAZ_RS42615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity