locus-tag	class	description
SLNHY_RS00070	COG0028	Belongs to the TPP enzyme family
SLNHY_RS00075	COG2072	flavoprotein involved in K transport
SLNHY_RS00085	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS00095	COG1024	Enoyl-CoA hydratase
SLNHY_RS00125	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS00130	COG2124	cytochrome p450
SLNHY_RS00140	COG1309	transcriptional regulator
SLNHY_RS00150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SLNHY_RS00155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SLNHY_RS00165	COG3485	protocatechuate 3,4-dioxygenase
SLNHY_RS00175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SLNHY_RS00180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SLNHY_RS00185	COG1414	Transcriptional regulator
SLNHY_RS00200	COG4120	Belongs to the binding-protein-dependent transport system permease family
SLNHY_RS00205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SLNHY_RS00215	COG1024	Enoyl-CoA hydratase
SLNHY_RS00225	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS00230	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS00245	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS00250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLNHY_RS00270	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS00275	COG0183	Belongs to the thiolase family
SLNHY_RS00280	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS00285	COG2267	carboxylic ester hydrolase activity
SLNHY_RS00290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLNHY_RS00305	COG1024	Enoyl-CoA hydratase
SLNHY_RS00310	COG1024	Enoyl-CoA hydratase
SLNHY_RS00315	COG1024	Enoyl-CoA hydratase
SLNHY_RS00325	COG4638	Rieske (2fe-2S)
SLNHY_RS00330	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
SLNHY_RS00340	COG0427	acetyl-CoA hydrolase
SLNHY_RS00345	COG0183	Belongs to the thiolase family
SLNHY_RS00355	COG0183	Belongs to the thiolase family
SLNHY_RS00360	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS00375	COG2301	Belongs to the HpcH HpaI aldolase family
SLNHY_RS00380	COG2030	dehydratase
SLNHY_RS00405	COG1733	regulation of RNA biosynthetic process
SLNHY_RS00435	COG2186	Transcriptional regulator
SLNHY_RS00450	COG0765	amino acid transport
SLNHY_RS00465	COG0667	Aldo Keto reductase
SLNHY_RS00485	COG2207	Transcriptional regulator
SLNHY_RS00505	COG1309	transcriptional regulator
SLNHY_RS00515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS00520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SLNHY_RS00525	COG3321	synthase
SLNHY_RS00525	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS00525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLNHY_RS00525	COG0300	oxidoreductase activity
SLNHY_RS00525	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS00550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS00555	COG4221	oxidoreductase activity
SLNHY_RS00605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLNHY_RS00605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLNHY_RS00655	COG0105	UTP biosynthetic process
SLNHY_RS00665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SLNHY_RS00675	COG0667	Aldo Keto reductase
SLNHY_RS00685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLNHY_RS00690	COG4569	acetaldehyde dehydrogenase (acetylating) activity
SLNHY_RS00725	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS00745	COG2376	Dihydroxyacetone kinase
SLNHY_RS00750	COG2376	Dihydroxyacetone kinase
SLNHY_RS00760	COG0129	dihydroxy-acid dehydratase activity
SLNHY_RS00765	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS00790	COG4770	biotin carboxylase activity
SLNHY_RS00825	COG2318	DinB family
SLNHY_RS00830	COG3467	pyridoxamine 5'-phosphate
SLNHY_RS00835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLNHY_RS00840	COG1132	(ABC) transporter
SLNHY_RS00860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SLNHY_RS00875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLNHY_RS00890	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLNHY_RS00895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLNHY_RS00930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLNHY_RS00940	COG0789	Transcriptional regulator
SLNHY_RS00970	COG0583	DNA-binding transcription factor activity
SLNHY_RS00995	COG3724	N-succinylarginine dihydrolase activity
SLNHY_RS01050	COG2115	Belongs to the xylose isomerase family
SLNHY_RS01055	COG1940	carbohydrate kinase activity
SLNHY_RS01065	COG2188	Transcriptional regulator
SLNHY_RS01075	COG2182	Extracellular solute-binding protein
SLNHY_RS01080	COG1175	transmembrane transport
SLNHY_RS01085	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS01095	COG2706	6-phosphogluconolactonase activity
SLNHY_RS01140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLNHY_RS01170	COG3559	Exporter of polyketide antibiotics
SLNHY_RS01175	COG1131	(ABC) transporter
SLNHY_RS01190	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SLNHY_RS01225	COG3321	synthase
SLNHY_RS01225	COG0604	alcohol dehydrogenase
SLNHY_RS01240	COG3321	synthase
SLNHY_RS01240	COG0604	alcohol dehydrogenase
SLNHY_RS01245	COG3321	synthase
SLNHY_RS01245	COG0604	alcohol dehydrogenase
SLNHY_RS01255	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLNHY_RS01275	COG2814	Major facilitator Superfamily
SLNHY_RS01280	COG1063	alcohol dehydrogenase
SLNHY_RS01285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLNHY_RS01290	COG1834	amidinotransferase
SLNHY_RS01320	COG0330	HflC and HflK could
SLNHY_RS01360	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS01370	COG0515	serine threonine protein kinase
SLNHY_RS01400	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS01405	COG1175	transmembrane transport
SLNHY_RS01435	COG2376	Dihydroxyacetone kinase
SLNHY_RS01440	COG1461	Dihydroxyacetone kinase
SLNHY_RS01460	COG1902	pentaerythritol trinitrate reductase activity
SLNHY_RS01460	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLNHY_RS01480	COG0435	Glutathione S-transferase
SLNHY_RS01500	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SLNHY_RS01505	COG1215	transferase activity, transferring glycosyl groups
SLNHY_RS01530	COG1349	DNA-binding transcription factor activity
SLNHY_RS01550	COG0577	efflux transmembrane transporter activity
SLNHY_RS01555	COG1136	(ABC) transporter
SLNHY_RS01570	COG1940	carbohydrate kinase activity
SLNHY_RS01580	COG0191	fructose-bisphosphate aldolase activity
SLNHY_RS01585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLNHY_RS01590	COG1349	DNA-binding transcription factor activity
SLNHY_RS01620	COG2197	response regulator
SLNHY_RS01625	COG4585	Histidine kinase
SLNHY_RS01630	COG0445	tRNA wobble uridine modification
SLNHY_RS01645	COG0477	Major facilitator Superfamily
SLNHY_RS01650	COG1051	belongs to the nudix hydrolase family
SLNHY_RS01670	COG0515	serine threonine protein kinase
SLNHY_RS01680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SLNHY_RS01705	COG0204	Acyl-transferase
SLNHY_RS01735	COG0584	glycerophosphoryl diester phosphodiesterase
SLNHY_RS01775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLNHY_RS01785	COG0488	(ABC) transporter
SLNHY_RS01795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SLNHY_RS01805	COG1113	amino acid transport
SLNHY_RS01810	COG0789	Transcriptional regulator
SLNHY_RS01815	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLNHY_RS01815	COG1024	Enoyl-CoA hydratase
SLNHY_RS01820	COG0183	Belongs to the thiolase family
SLNHY_RS01825	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS01830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLNHY_RS01835	COG3268	Saccharopine dehydrogenase
SLNHY_RS01840	COG1515	deoxyribonuclease V activity
SLNHY_RS01855	COG0488	(ABC) transporter
SLNHY_RS01880	COG1793	dna ligase
SLNHY_RS01895	COG1672	PFAM Archaeal ATPase
SLNHY_RS01895	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLNHY_RS01930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLNHY_RS01935	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SLNHY_RS01965	COG2154	pterin-4-alpha-carbinolamine dehydratase
SLNHY_RS01990	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SLNHY_RS02030	COG0457	Tetratricopeptide repeat
SLNHY_RS02035	COG0456	acetyltransferase
SLNHY_RS02035	COG0454	-acetyltransferase
SLNHY_RS02045	COG1619	proteins homologs of microcin C7 resistance protein MccF
SLNHY_RS02055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLNHY_RS02060	COG2362	D-Aminopeptidase
SLNHY_RS02105	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLNHY_RS02115	COG0604	alcohol dehydrogenase
SLNHY_RS02120	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLNHY_RS02120	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLNHY_RS02125	COG2301	Belongs to the HpcH HpaI aldolase family
SLNHY_RS02135	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS02140	COG0688	phosphatidylethanolamine metabolic process
SLNHY_RS02150	COG1929	Belongs to the glycerate kinase type-1 family
SLNHY_RS02155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SLNHY_RS02180	COG3511	phospholipase C
SLNHY_RS02195	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS02220	COG0596	Alpha beta hydrolase
SLNHY_RS02230	COG1609	Transcriptional regulator
SLNHY_RS02240	COG1175	transmembrane transport
SLNHY_RS02245	COG3833	ABC-type maltose transport systems, permease component
SLNHY_RS02250	COG0366	Alpha amylase catalytic
SLNHY_RS02270	COG0483	inositol monophosphate 1-phosphatase activity
SLNHY_RS02305	COG0405	Gamma-glutamyltransferase
SLNHY_RS02325	COG1357	PFAM Pentapeptide repeats (8 copies)
SLNHY_RS02340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLNHY_RS02360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLNHY_RS02365	COG0765	amino acid transport
SLNHY_RS02385	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS02390	COG1794	racemase activity, acting on amino acids and derivatives
SLNHY_RS02460	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS02465	COG1809	phosphosulfolactate synthase activity
SLNHY_RS02475	COG1132	(ABC) transporter
SLNHY_RS02480	COG1132	(ABC) transporter
SLNHY_RS02495	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS02500	COG1175	transmembrane transport
SLNHY_RS02540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SLNHY_RS02555	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLNHY_RS02565	COG1940	carbohydrate kinase activity
SLNHY_RS02585	COG2188	Transcriptional regulator
SLNHY_RS02590	COG0673	inositol 2-dehydrogenase activity
SLNHY_RS02600	COG2197	response regulator
SLNHY_RS02625	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS02630	COG4266	Belongs to the allantoicase family
SLNHY_RS02635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLNHY_RS02650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SLNHY_RS02665	COG1940	carbohydrate kinase activity
SLNHY_RS02670	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SLNHY_RS02675	COG2223	nitrite transmembrane transporter activity
SLNHY_RS02685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SLNHY_RS02700	COG0438	transferase activity, transferring glycosyl groups
SLNHY_RS02705	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS02715	COG1940	carbohydrate kinase activity
SLNHY_RS02730	COG1082	Xylose isomerase domain protein TIM barrel
SLNHY_RS02750	COG3321	synthase
SLNHY_RS02750	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS02750	COG0604	alcohol dehydrogenase
SLNHY_RS02760	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS02765	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS02775	COG1309	transcriptional regulator
SLNHY_RS02780	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLNHY_RS02780	COG1902	pentaerythritol trinitrate reductase activity
SLNHY_RS02785	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS02800	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS02805	COG1733	regulation of RNA biosynthetic process
SLNHY_RS02810	COG0436	Aminotransferase
SLNHY_RS02815	COG0406	alpha-ribazole phosphatase activity
SLNHY_RS02865	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS02870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLNHY_RS02900	COG2340	Cysteine-rich secretory protein family
SLNHY_RS02905	COG2186	Transcriptional regulator
SLNHY_RS02915	COG1129	ABC transporter
SLNHY_RS02925	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLNHY_RS02930	COG4948	Mandelate Racemase Muconate Lactonizing
SLNHY_RS02945	COG0247	lactate metabolic process
SLNHY_RS02950	COG1139	Iron-sulfur cluster binding protein
SLNHY_RS02955	COG1556	Lactate utilization protein
SLNHY_RS02985	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLNHY_RS02985	COG1672	PFAM Archaeal ATPase
SLNHY_RS03005	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLNHY_RS03010	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SLNHY_RS03015	COG2080	2 iron, 2 sulfur cluster binding
SLNHY_RS03050	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SLNHY_RS03050	COG3608	succinylglutamate desuccinylase aspartoacylase
SLNHY_RS03055	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLNHY_RS03085	COG1802	Transcriptional regulator
SLNHY_RS03110	COG0028	Belongs to the TPP enzyme family
SLNHY_RS03125	COG1819	glycosyl
SLNHY_RS03140	COG3629	intracellular signal transduction
SLNHY_RS03160	COG2124	cytochrome p450
SLNHY_RS03170	COG2197	response regulator
SLNHY_RS03190	COG0604	alcohol dehydrogenase
SLNHY_RS03190	COG3321	synthase
SLNHY_RS03195	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SLNHY_RS03200	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLNHY_RS03215	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SLNHY_RS03220	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLNHY_RS03235	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS03245	COG0604	alcohol dehydrogenase
SLNHY_RS03245	COG3321	synthase
SLNHY_RS03255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SLNHY_RS03285	COG1309	transcriptional regulator
SLNHY_RS03295	COG3321	synthase
SLNHY_RS03295	COG0604	alcohol dehydrogenase
SLNHY_RS03300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLNHY_RS03320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SLNHY_RS03330	COG1162	GTPase activity
SLNHY_RS03335	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SLNHY_RS03355	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SLNHY_RS03360	COG0765	amino acid transport
SLNHY_RS03375	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS03435	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS03455	COG0175	sulfate reduction
SLNHY_RS03460	COG0529	Catalyzes the synthesis of activated sulfate
SLNHY_RS03480	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SLNHY_RS03485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLNHY_RS03495	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SLNHY_RS03510	COG2409	Drug exporters of the RND superfamily
SLNHY_RS03535	COG1175	transmembrane transport
SLNHY_RS03545	COG0539	negative regulation of cytoplasmic translation
SLNHY_RS03600	COG1191	sigma factor activity
SLNHY_RS03615	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SLNHY_RS03620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SLNHY_RS03665	COG4152	abc transporter atp-binding protein
SLNHY_RS03675	COG3220	belongs to the UPF0276 family
SLNHY_RS03695	COG3253	May function as heme-dependent peroxidase
SLNHY_RS03700	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SLNHY_RS03705	COG0446	pyridine nucleotide-disulphide oxidoreductase
SLNHY_RS03715	COG0438	transferase activity, transferring glycosyl groups
SLNHY_RS03725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLNHY_RS03730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SLNHY_RS03750	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SLNHY_RS03765	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SLNHY_RS03770	COG0183	Belongs to the thiolase family
SLNHY_RS03775	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLNHY_RS03775	COG1024	Enoyl-CoA hydratase
SLNHY_RS03790	COG1196	nuclear chromosome segregation
SLNHY_RS03790	COG0741	lytic transglycosylase activity
SLNHY_RS03790	COG0739	heme binding
SLNHY_RS03795	COG0531	amino acid
SLNHY_RS03800	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SLNHY_RS03805	COG4214	carbohydrate transport
SLNHY_RS03815	COG4213	ABC transporter substrate-binding protein
SLNHY_RS03820	COG1940	carbohydrate kinase activity
SLNHY_RS03865	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS03870	COG1175	transmembrane transport
SLNHY_RS03875	COG1653	transport
SLNHY_RS03880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SLNHY_RS03885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SLNHY_RS03900	COG1472	Belongs to the glycosyl hydrolase 3 family
SLNHY_RS03905	COG2066	Belongs to the glutaminase family
SLNHY_RS03915	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS03920	COG2205	protein histidine kinase activity
SLNHY_RS03945	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS03955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLNHY_RS03970	COG1175	transmembrane transport
SLNHY_RS03975	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS03990	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS04020	COG2208	phosphoserine phosphatase activity
SLNHY_RS04020	COG1366	Belongs to the anti-sigma-factor antagonist family
SLNHY_RS04020	COG2172	sigma factor antagonist activity
SLNHY_RS04050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SLNHY_RS04080	COG1799	cell septum assembly
SLNHY_RS04085	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SLNHY_RS04105	COG2814	Major facilitator Superfamily
SLNHY_RS04115	COG0477	Major facilitator Superfamily
SLNHY_RS04120	COG0604	alcohol dehydrogenase
SLNHY_RS04120	COG3321	synthase
SLNHY_RS04135	COG3321	synthase
SLNHY_RS04135	COG0604	alcohol dehydrogenase
SLNHY_RS04155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLNHY_RS04160	COG1819	glycosyl
SLNHY_RS04175	COG3321	synthase
SLNHY_RS04175	COG0604	alcohol dehydrogenase
SLNHY_RS04180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
SLNHY_RS04195	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SLNHY_RS04210	COG1773	rubredoxin
SLNHY_RS04220	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SLNHY_RS04225	COG1309	transcriptional regulator
SLNHY_RS04230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLNHY_RS04275	COG4865	methylaspartate mutase activity
SLNHY_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS04335	COG4948	Mandelate Racemase Muconate Lactonizing
SLNHY_RS04390	COG3629	intracellular signal transduction
SLNHY_RS04390	COG3903	Transcriptional regulator
SLNHY_RS04410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLNHY_RS04430	COG0667	Aldo Keto reductase
SLNHY_RS04435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS04440	COG1116	anion transmembrane transporter activity
SLNHY_RS04445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLNHY_RS04460	COG1846	Transcriptional regulator
SLNHY_RS04460	COG1940	carbohydrate kinase activity
SLNHY_RS04480	COG1535	isochorismatase
SLNHY_RS04480	COG3433	isochorismatase activity
SLNHY_RS04485	COG1535	isochorismatase
SLNHY_RS04485	COG3433	isochorismatase activity
SLNHY_RS04490	COG1021	2,3-dihydroxybenzoate-AMP ligase
SLNHY_RS04495	COG1169	isochorismate synthase
SLNHY_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS04515	COG4977	sequence-specific DNA binding
SLNHY_RS04525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLNHY_RS04530	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS04560	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SLNHY_RS04590	COG0673	inositol 2-dehydrogenase activity
SLNHY_RS04595	COG1366	Belongs to the anti-sigma-factor antagonist family
SLNHY_RS04595	COG2172	sigma factor antagonist activity
SLNHY_RS04595	COG2208	phosphoserine phosphatase activity
SLNHY_RS04660	COG0438	transferase activity, transferring glycosyl groups
SLNHY_RS04705	COG0515	serine threonine protein kinase
SLNHY_RS04705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLNHY_RS04725	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS04730	COG1063	alcohol dehydrogenase
SLNHY_RS04745	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS04750	COG1309	transcriptional regulator
SLNHY_RS04770	COG0739	heme binding
SLNHY_RS04770	COG0741	lytic transglycosylase activity
SLNHY_RS04770	COG1196	nuclear chromosome segregation
SLNHY_RS04785	COG3537	Alpha-1,2-mannosidase
SLNHY_RS04795	COG2133	pyrroloquinoline quinone binding
SLNHY_RS04795	COG5183	chlorophyll binding
SLNHY_RS04800	COG1609	Transcriptional regulator
SLNHY_RS04805	COG1879	ABC-type sugar transport system periplasmic component
SLNHY_RS04810	COG1129	ABC transporter
SLNHY_RS04815	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLNHY_RS04820	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLNHY_RS04850	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SLNHY_RS04850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SLNHY_RS04870	COG1174	glycine betaine transport
SLNHY_RS04900	COG0604	alcohol dehydrogenase
SLNHY_RS04900	COG3321	synthase
SLNHY_RS04920	COG0009	L-threonylcarbamoyladenylate synthase
SLNHY_RS04940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SLNHY_RS04965	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SLNHY_RS04970	COG0142	geranyltranstransferase activity
SLNHY_RS04985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLNHY_RS05005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SLNHY_RS05010	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SLNHY_RS05045	COG2409	Drug exporters of the RND superfamily
SLNHY_RS05050	COG3903	Transcriptional regulator
SLNHY_RS05050	COG3629	intracellular signal transduction
SLNHY_RS05055	COG2843	Capsule synthesis protein
SLNHY_RS05070	COG0142	geranyltranstransferase activity
SLNHY_RS05090	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SLNHY_RS05145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SLNHY_RS05150	COG1335	isochorismatase
SLNHY_RS05155	COG0473	3-isopropylmalate dehydrogenase activity
SLNHY_RS05175	COG4221	oxidoreductase activity
SLNHY_RS05200	COG0747	negative chemotaxis
SLNHY_RS05210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLNHY_RS05220	COG4608	Belongs to the ABC transporter superfamily
SLNHY_RS05225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS05240	COG0431	NADPH-dependent FMN reductase
SLNHY_RS05255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLNHY_RS05310	COG1940	carbohydrate kinase activity
SLNHY_RS05315	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS05320	COG1175	transmembrane transport
SLNHY_RS05330	COG1063	alcohol dehydrogenase
SLNHY_RS05335	COG1082	Xylose isomerase domain protein TIM barrel
SLNHY_RS05340	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SLNHY_RS05375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SLNHY_RS05390	COG3387	PFAM Glycoside hydrolase 15-related
SLNHY_RS05460	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SLNHY_RS05470	COG1132	(ABC) transporter
SLNHY_RS05475	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SLNHY_RS05515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLNHY_RS05540	COG0154	amidase activity
SLNHY_RS05660	COG0640	Transcriptional regulator
SLNHY_RS05680	COG1742	UPF0060 membrane protein
SLNHY_RS05690	COG2072	flavoprotein involved in K transport
SLNHY_RS05695	COG0798	PFAM Bile acid sodium symporter
SLNHY_RS05705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLNHY_RS05710	COG0492	ferredoxin-NADP+ reductase activity
SLNHY_RS05720	COG2259	Doxx family
SLNHY_RS05725	COG1695	Transcriptional regulator
SLNHY_RS05730	COG0701	Predicted permease
SLNHY_RS05745	COG0671	phosphoesterase, PA-phosphatase related
SLNHY_RS05750	COG1968	undecaprenyl-diphosphatase activity
SLNHY_RS05760	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLNHY_RS05765	COG1993	acr, cog1993
SLNHY_RS05770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLNHY_RS05775	COG0492	ferredoxin-NADP+ reductase activity
SLNHY_RS05815	COG0693	protein deglycase activity
SLNHY_RS05845	COG0656	L-ascorbic acid biosynthetic process
SLNHY_RS05860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLNHY_RS05870	COG2132	Multicopper oxidase
SLNHY_RS05875	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLNHY_RS05885	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLNHY_RS05895	COG0713	ATP synthesis coupled electron transport
SLNHY_RS05900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SLNHY_RS05910	COG1007	ATP synthesis coupled electron transport
SLNHY_RS06035	COG3883	PFAM NLP P60 protein
SLNHY_RS06035	COG0791	NLP P60 protein
SLNHY_RS06140	COG0714	Associated with various cellular activities
SLNHY_RS06260	COG0159	tryptophan synthase activity
SLNHY_RS06290	COG1278	Cold shock
SLNHY_RS06305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLNHY_RS06330	COG0582	viral genome integration into host DNA
SLNHY_RS06385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SLNHY_RS06390	COG0531	amino acid
SLNHY_RS06395	COG0569	domain protein
SLNHY_RS06435	COG0756	dUTP diphosphatase activity
SLNHY_RS06460	COG2205	protein histidine kinase activity
SLNHY_RS06465	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS06475	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SLNHY_RS06505	COG1435	thymidine kinase activity
SLNHY_RS06525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SLNHY_RS06530	COG1802	Transcriptional regulator
SLNHY_RS06535	COG0739	heme binding
SLNHY_RS06545	COG0612	Peptidase, M16
SLNHY_RS06550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SLNHY_RS06565	COG0372	Belongs to the citrate synthase family
SLNHY_RS06580	COG3290	protein histidine kinase activity
SLNHY_RS06590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLNHY_RS06610	COG0187	DNA topoisomerase II activity
SLNHY_RS06625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLNHY_RS06630	COG2186	Transcriptional regulator
SLNHY_RS06670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SLNHY_RS06695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SLNHY_RS06700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SLNHY_RS06705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SLNHY_RS06720	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS06765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SLNHY_RS06780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLNHY_RS06805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLNHY_RS06835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SLNHY_RS06840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SLNHY_RS06850	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SLNHY_RS06865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SLNHY_RS06890	COG1609	Transcriptional regulator
SLNHY_RS06895	COG1653	transport
SLNHY_RS06900	COG1175	transmembrane transport
SLNHY_RS06905	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS06930	COG1126	abc transporter atp-binding protein
SLNHY_RS06935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLNHY_RS06940	COG0765	amino acid transport
SLNHY_RS06945	COG0765	amino acid transport
SLNHY_RS06960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SLNHY_RS06970	COG2137	regulation of response to DNA damage stimulus
SLNHY_RS06975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SLNHY_RS07010	COG2207	Transcriptional regulator
SLNHY_RS07010	COG1917	Cupin 2, conserved barrel domain protein
SLNHY_RS07015	COG1201	RNA secondary structure unwinding
SLNHY_RS07020	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLNHY_RS07025	COG0783	Belongs to the Dps family
SLNHY_RS07030	COG1396	sequence-specific DNA binding
SLNHY_RS07035	COG1546	Belongs to the CinA family
SLNHY_RS07035	COG1058	Belongs to the CinA family
SLNHY_RS07045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SLNHY_RS07055	COG1674	ftsk spoiiie
SLNHY_RS07065	COG3850	Histidine kinase
SLNHY_RS07065	COG4999	Histidine kinase
SLNHY_RS07065	COG3437	response regulator, receiver
SLNHY_RS07065	COG2205	protein histidine kinase activity
SLNHY_RS07070	COG2770	Histidine kinase
SLNHY_RS07070	COG2208	phosphoserine phosphatase activity
SLNHY_RS07100	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SLNHY_RS07105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLNHY_RS07110	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SLNHY_RS07135	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SLNHY_RS07140	COG0612	Peptidase, M16
SLNHY_RS07145	COG1185	polyribonucleotide nucleotidyltransferase activity
SLNHY_RS07150	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SLNHY_RS07170	COG0455	bacterial-type flagellum organization
SLNHY_RS07175	COG0747	negative chemotaxis
SLNHY_RS07180	COG0601	transmembrane transport
SLNHY_RS07185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLNHY_RS07210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SLNHY_RS07215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SLNHY_RS07225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SLNHY_RS07240	COG0779	Required for maturation of 30S ribosomal subunits
SLNHY_RS07260	COG0442	prolyl-tRNA aminoacylation
SLNHY_RS07275	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SLNHY_RS07280	COG0750	zinc metalloprotease
SLNHY_RS07285	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SLNHY_RS07300	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS07305	COG2508	Transcriptional regulator
SLNHY_RS07345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLNHY_RS07365	COG5640	endopeptidase activity
SLNHY_RS07370	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS07400	COG3842	ATPase activity
SLNHY_RS07415	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SLNHY_RS07420	COG1725	Transcriptional regulator
SLNHY_RS07450	COG0233	cytoplasmic translational termination
SLNHY_RS07455	COG0528	UMP kinase activity
SLNHY_RS07460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SLNHY_RS07465	COG0052	Belongs to the universal ribosomal protein uS2 family
SLNHY_RS07480	COG1191	sigma factor activity
SLNHY_RS07500	COG0789	Transcriptional regulator
SLNHY_RS07545	COG1051	belongs to the nudix hydrolase family
SLNHY_RS07550	COG0681	Belongs to the peptidase S26 family
SLNHY_RS07555	COG0681	Belongs to the peptidase S26 family
SLNHY_RS07565	COG0335	large ribosomal subunit rRNA binding
SLNHY_RS07570	COG0336	Belongs to the RNA methyltransferase TrmD family
SLNHY_RS07575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SLNHY_RS07580	COG1837	Belongs to the UPF0109 family
SLNHY_RS07585	COG0228	four-way junction DNA binding
SLNHY_RS07605	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SLNHY_RS07635	COG0477	Major facilitator Superfamily
SLNHY_RS07640	COG1196	nuclear chromosome segregation
SLNHY_RS07650	COG1254	Belongs to the acylphosphatase family
SLNHY_RS07655	COG2340	Cysteine-rich secretory protein family
SLNHY_RS07660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLNHY_RS07665	COG0571	ribonuclease III activity
SLNHY_RS07670	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SLNHY_RS07685	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SLNHY_RS07690	COG0742	ribosomal rna small subunit methyltransferase
SLNHY_RS07695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SLNHY_RS07700	COG0326	Molecular chaperone. Has ATPase activity
SLNHY_RS07710	COG1461	Dihydroxyacetone kinase
SLNHY_RS07715	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SLNHY_RS07720	COG0351	phosphomethylpyrimidine kinase
SLNHY_RS07740	COG1181	Belongs to the D-alanine--D-alanine ligase family
SLNHY_RS07745	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SLNHY_RS07755	COG1920	GTP binding
SLNHY_RS07765	COG0776	regulation of translation
SLNHY_RS07775	COG0066	3-isopropylmalate dehydratase activity
SLNHY_RS07780	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SLNHY_RS07785	COG1414	Transcriptional regulator
SLNHY_RS07830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SLNHY_RS07835	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLNHY_RS07850	COG2018	Roadblock/LC7 domain
SLNHY_RS07870	COG2018	Roadblock/LC7 domain
SLNHY_RS07890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLNHY_RS07900	COG2353	YceI-like domain
SLNHY_RS07915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLNHY_RS07920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SLNHY_RS07925	COG0473	3-isopropylmalate dehydrogenase activity
SLNHY_RS07940	COG0583	DNA-binding transcription factor activity
SLNHY_RS07945	COG2130	NADP-dependent
SLNHY_RS07950	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS07955	COG0506	proline dehydrogenase activity
SLNHY_RS07960	COG3835	regulator
SLNHY_RS07965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLNHY_RS07970	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SLNHY_RS07975	COG0440	acetolactate synthase activity
SLNHY_RS07995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SLNHY_RS08005	COG1621	beta-fructofuranosidase activity
SLNHY_RS08060	COG2409	Drug exporters of the RND superfamily
SLNHY_RS08070	COG2207	Transcriptional regulator
SLNHY_RS08070	COG3708	Transcriptional regulator
SLNHY_RS08080	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SLNHY_RS08090	COG1196	nuclear chromosome segregation
SLNHY_RS08100	COG0154	amidase activity
SLNHY_RS08105	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SLNHY_RS08115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SLNHY_RS08125	COG4221	oxidoreductase activity
SLNHY_RS08130	COG1611	Belongs to the LOG family
SLNHY_RS08150	COG0482	sulfurtransferase activity
SLNHY_RS08205	COG2378	regulation of single-species biofilm formation
SLNHY_RS08215	COG2860	membrane
SLNHY_RS08220	COG4608	Belongs to the ABC transporter superfamily
SLNHY_RS08225	COG0444	Belongs to the ABC transporter superfamily
SLNHY_RS08230	COG0601	transmembrane transport
SLNHY_RS08235	COG0747	negative chemotaxis
SLNHY_RS08260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SLNHY_RS08265	COG0509	glycine decarboxylation via glycine cleavage system
SLNHY_RS08270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLNHY_RS08275	COG1760	l-serine dehydratase
SLNHY_RS08295	COG0259	pyridoxamine-phosphate oxidase activity
SLNHY_RS08305	COG0148	phosphopyruvate hydratase activity
SLNHY_RS08325	COG1063	alcohol dehydrogenase
SLNHY_RS08330	COG1295	ribonuclease BN
SLNHY_RS08360	COG1802	Transcriptional regulator
SLNHY_RS08365	COG0006	proline dipeptidase activity
SLNHY_RS08390	COG3391	amine dehydrogenase activity
SLNHY_RS08425	COG1132	(ABC) transporter
SLNHY_RS08430	COG1132	(ABC) transporter
SLNHY_RS08435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLNHY_RS08440	COG1802	Transcriptional regulator
SLNHY_RS08475	COG0058	SHG alpha-glucan phosphorylase activity
SLNHY_RS08480	COG0366	Alpha amylase catalytic
SLNHY_RS08490	COG3281	Trehalose synthase
SLNHY_RS08495	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SLNHY_RS08535	COG4565	transcriptional regulatory protein
SLNHY_RS08545	COG1175	transmembrane transport
SLNHY_RS08550	COG3833	ABC-type maltose transport systems, permease component
SLNHY_RS08585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SLNHY_RS08605	COG0205	6-phosphofructokinase activity
SLNHY_RS08610	COG0280	phosphate acetyltransferase
SLNHY_RS08610	COG0857	belongs to the CobB CobQ family
SLNHY_RS08615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SLNHY_RS08655	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLNHY_RS08655	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLNHY_RS08720	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS08735	COG0183	Belongs to the thiolase family
SLNHY_RS08755	COG1131	(ABC) transporter
SLNHY_RS08770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLNHY_RS08775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLNHY_RS08810	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SLNHY_RS08825	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLNHY_RS08830	COG1309	transcriptional regulator
SLNHY_RS08845	COG1595	DNA-templated transcription, initiation
SLNHY_RS08850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLNHY_RS08865	COG3850	Histidine kinase
SLNHY_RS08870	COG2197	response regulator
SLNHY_RS08890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SLNHY_RS08895	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SLNHY_RS08900	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SLNHY_RS08905	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SLNHY_RS08910	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SLNHY_RS08915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SLNHY_RS08920	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SLNHY_RS08935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SLNHY_RS08940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SLNHY_RS08945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLNHY_RS08955	COG2890	protein-(glutamine-N5) methyltransferase activity
SLNHY_RS08960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SLNHY_RS08965	COG0254	rRNA binding
SLNHY_RS08990	COG0083	homoserine kinase activity
SLNHY_RS08995	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SLNHY_RS09000	COG0460	homoserine dehydrogenase
SLNHY_RS09005	COG0019	diaminopimelate decarboxylase activity
SLNHY_RS09010	COG0018	arginyl-trna synthetase
SLNHY_RS09020	COG3654	unkown
SLNHY_RS09035	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS09055	COG0151	Belongs to the GarS family
SLNHY_RS09070	COG0640	Transcriptional regulator
SLNHY_RS09095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS09115	COG0326	Molecular chaperone. Has ATPase activity
SLNHY_RS09130	COG0328	RNA-DNA hybrid ribonuclease activity
SLNHY_RS09150	COG2890	protein-(glutamine-N5) methyltransferase activity
SLNHY_RS09160	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SLNHY_RS09165	COG1793	dna ligase
SLNHY_RS09165	COG3285	dna ligase
SLNHY_RS09180	COG0772	Belongs to the SEDS family
SLNHY_RS09260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SLNHY_RS09275	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS09280	COG2205	protein histidine kinase activity
SLNHY_RS09285	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLNHY_RS09285	COG0567	Dehydrogenase, E1 component
SLNHY_RS09295	COG2755	lipolytic protein G-D-S-L family
SLNHY_RS09335	COG0604	alcohol dehydrogenase
SLNHY_RS09355	COG1126	abc transporter atp-binding protein
SLNHY_RS09360	COG4106	trans-aconitate 2-methyltransferase activity
SLNHY_RS09385	COG1309	transcriptional regulator
SLNHY_RS09450	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS09455	COG4941	Belongs to the sigma-70 factor family
SLNHY_RS09480	COG0142	geranyltranstransferase activity
SLNHY_RS09485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLNHY_RS09525	COG1597	lipid kinase activity
SLNHY_RS09540	COG0363	glucosamine-6-phosphate deaminase activity
SLNHY_RS09545	COG1472	Belongs to the glycosyl hydrolase 3 family
SLNHY_RS09550	COG2188	Transcriptional regulator
SLNHY_RS09575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SLNHY_RS09580	COG2124	cytochrome p450
SLNHY_RS09590	COG0242	peptide deformylase activity
SLNHY_RS09610	COG5662	AntiSigma factor
SLNHY_RS09615	COG1595	DNA-templated transcription, initiation
SLNHY_RS09630	COG2135	peptidase activity
SLNHY_RS09635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SLNHY_RS09640	COG1162	GTPase activity
SLNHY_RS09645	COG2076	Multidrug Resistance protein
SLNHY_RS09655	COG0483	inositol monophosphate 1-phosphatase activity
SLNHY_RS09665	COG0753	catalase activity
SLNHY_RS09695	COG1615	UPF0182 protein
SLNHY_RS09705	COG3480	Lon protease (S16) C-terminal proteolytic domain
SLNHY_RS09755	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SLNHY_RS09820	COG0210	DNA helicase
SLNHY_RS09850	COG0596	Alpha beta hydrolase
SLNHY_RS09860	COG1733	regulation of RNA biosynthetic process
SLNHY_RS09900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLNHY_RS09945	COG0513	Belongs to the DEAD box helicase family
SLNHY_RS09960	COG0542	response to heat
SLNHY_RS09970	COG1432	Conserved Protein
SLNHY_RS09975	COG2095	MarC family integral membrane protein
SLNHY_RS09980	COG0613	PHP domain protein
SLNHY_RS09990	COG2814	Major facilitator Superfamily
SLNHY_RS10000	COG0598	Magnesium transport protein CorA
SLNHY_RS10035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLNHY_RS10040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLNHY_RS10050	COG1595	DNA-templated transcription, initiation
SLNHY_RS10065	COG1024	Enoyl-CoA hydratase
SLNHY_RS10070	COG2818	Glycosylase
SLNHY_RS10085	COG1611	Belongs to the LOG family
SLNHY_RS10090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLNHY_RS10115	COG0456	acetyltransferase
SLNHY_RS10115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLNHY_RS10125	COG2197	response regulator
SLNHY_RS10130	COG4585	Histidine kinase
SLNHY_RS10140	COG1131	(ABC) transporter
SLNHY_RS10160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLNHY_RS10175	COG4608	Belongs to the ABC transporter superfamily
SLNHY_RS10185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLNHY_RS10190	COG0601	transmembrane transport
SLNHY_RS10225	COG1733	regulation of RNA biosynthetic process
SLNHY_RS10240	COG0604	alcohol dehydrogenase
SLNHY_RS10240	COG3321	synthase
SLNHY_RS10280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLNHY_RS10310	COG4608	Belongs to the ABC transporter superfamily
SLNHY_RS10315	COG0444	Belongs to the ABC transporter superfamily
SLNHY_RS10330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLNHY_RS10335	COG1217	gtp-binding protein TYPA
SLNHY_RS10375	COG0667	Aldo Keto reductase
SLNHY_RS10410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLNHY_RS10415	COG1946	Acyl-CoA thioesterase
SLNHY_RS10420	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS10440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLNHY_RS10450	COG2409	Drug exporters of the RND superfamily
SLNHY_RS10575	COG0464	growth
SLNHY_RS10605	COG0012	GTP binding
SLNHY_RS10620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SLNHY_RS10625	COG1570	exodeoxyribonuclease VII activity
SLNHY_RS10630	COG1722	exodeoxyribonuclease VII activity
SLNHY_RS10635	COG0778	Nitroreductase
SLNHY_RS10660	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SLNHY_RS10660	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SLNHY_RS10685	COG0114	fumarate hydratase activity
SLNHY_RS10695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SLNHY_RS10710	COG4977	sequence-specific DNA binding
SLNHY_RS10720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLNHY_RS10740	COG1136	(ABC) transporter
SLNHY_RS10760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLNHY_RS10775	COG0515	serine threonine protein kinase
SLNHY_RS10780	COG2319	Wd-40 repeat
SLNHY_RS10780	COG4249	Peptidase C14 caspase catalytic subunit p20
SLNHY_RS10790	COG1309	transcriptional regulator
SLNHY_RS10795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLNHY_RS10810	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS10850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SLNHY_RS10855	COG0589	response to stress
SLNHY_RS10860	COG4977	sequence-specific DNA binding
SLNHY_RS10865	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SLNHY_RS10880	COG0673	inositol 2-dehydrogenase activity
SLNHY_RS10885	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS10970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS11040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SLNHY_RS11045	COG0154	amidase activity
SLNHY_RS11055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLNHY_RS11060	COG0765	amino acid transport
SLNHY_RS11065	COG0765	amino acid transport
SLNHY_RS11070	COG1126	abc transporter atp-binding protein
SLNHY_RS11125	COG2186	Transcriptional regulator
SLNHY_RS11195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SLNHY_RS11205	COG2188	Transcriptional regulator
SLNHY_RS11210	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SLNHY_RS11215	COG0477	Major facilitator Superfamily
SLNHY_RS11225	COG0673	inositol 2-dehydrogenase activity
SLNHY_RS11230	COG0706	membrane insertase activity
SLNHY_RS11260	COG2271	Major facilitator Superfamily
SLNHY_RS11265	COG2814	Major facilitator Superfamily
SLNHY_RS11280	COG2733	membrane
SLNHY_RS11300	COG1131	(ABC) transporter
SLNHY_RS11315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLNHY_RS11345	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SLNHY_RS11355	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SLNHY_RS11360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SLNHY_RS11365	COG1234	tRNA 3'-trailer cleavage
SLNHY_RS11380	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SLNHY_RS11385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLNHY_RS11395	COG1113	amino acid transport
SLNHY_RS11405	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SLNHY_RS11415	COG1335	isochorismatase
SLNHY_RS11455	COG0277	FAD linked oxidase domain protein
SLNHY_RS11460	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SLNHY_RS11470	COG3480	Lon protease (S16) C-terminal proteolytic domain
SLNHY_RS11505	COG1024	Enoyl-CoA hydratase
SLNHY_RS11520	COG0300	oxidoreductase activity
SLNHY_RS11540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SLNHY_RS11560	COG1678	Uncharacterized ACR, COG1678
SLNHY_RS11565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SLNHY_RS11570	COG0776	regulation of translation
SLNHY_RS11580	COG3973	AAA domain
SLNHY_RS11605	COG2223	nitrite transmembrane transporter activity
SLNHY_RS11655	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SLNHY_RS11660	COG0793	Belongs to the peptidase S41A family
SLNHY_RS11660	COG3409	Peptidoglycan-binding domain 1 protein
SLNHY_RS11670	COG2884	Cell division ATP-binding protein ftsE
SLNHY_RS11685	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SLNHY_RS11690	COG0515	serine threonine protein kinase
SLNHY_RS11695	COG0515	serine threonine protein kinase
SLNHY_RS11715	COG1175	transmembrane transport
SLNHY_RS11720	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS11730	COG1764	response to oxidative stress
SLNHY_RS11735	COG1846	Transcriptional regulator
SLNHY_RS11745	COG2318	DinB family
SLNHY_RS11780	COG2902	Dehydrogenase
SLNHY_RS11800	COG0653	protein targeting
SLNHY_RS11810	COG3214	Protein conserved in bacteria
SLNHY_RS11815	COG2197	response regulator
SLNHY_RS11820	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SLNHY_RS11825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SLNHY_RS11830	COG0823	Involved in the tonB-independent uptake of proteins
SLNHY_RS11835	COG5002	protein histidine kinase activity
SLNHY_RS11840	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS11845	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SLNHY_RS11865	COG0714	Associated with various cellular activities
SLNHY_RS11905	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SLNHY_RS11915	COG1482	cell wall glycoprotein biosynthetic process
SLNHY_RS11925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLNHY_RS11965	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SLNHY_RS11970	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SLNHY_RS11970	COG0778	Nitroreductase
SLNHY_RS12000	COG1316	TRANSCRIPTIONal
SLNHY_RS12020	COG0366	Alpha amylase catalytic
SLNHY_RS12025	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS12030	COG1175	transmembrane transport
SLNHY_RS12065	COG1316	TRANSCRIPTIONal
SLNHY_RS12075	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SLNHY_RS12100	COG2205	protein histidine kinase activity
SLNHY_RS12105	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS12110	COG3104	oligopeptide transport
SLNHY_RS12120	COG1366	Belongs to the anti-sigma-factor antagonist family
SLNHY_RS12125	COG1191	sigma factor activity
SLNHY_RS12130	COG1228	amidohydrolase
SLNHY_RS12145	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SLNHY_RS12150	COG0019	diaminopimelate decarboxylase activity
SLNHY_RS12180	COG2755	lipolytic protein G-D-S-L family
SLNHY_RS12185	COG0183	Belongs to the thiolase family
SLNHY_RS12215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLNHY_RS12240	COG0148	phosphopyruvate hydratase activity
SLNHY_RS12255	COG2124	cytochrome p450
SLNHY_RS12290	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLNHY_RS12295	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS12300	COG2188	Transcriptional regulator
SLNHY_RS12315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLNHY_RS12325	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SLNHY_RS12330	COG1733	regulation of RNA biosynthetic process
SLNHY_RS12365	COG1007	ATP synthesis coupled electron transport
SLNHY_RS12375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SLNHY_RS12380	COG0713	ATP synthesis coupled electron transport
SLNHY_RS12385	COG0839	Belongs to the complex I subunit 6 family
SLNHY_RS12390	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLNHY_RS12395	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLNHY_RS12400	COG1034	ATP synthesis coupled electron transport
SLNHY_RS12405	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SLNHY_RS12415	COG0649	NAD binding
SLNHY_RS12420	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLNHY_RS12425	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLNHY_RS12460	COG2226	methyltransferase
SLNHY_RS12470	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLNHY_RS12560	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
SLNHY_RS12645	COG0494	nUDIX hydrolase
SLNHY_RS12655	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SLNHY_RS12660	COG1278	Cold shock
SLNHY_RS12670	COG0183	Belongs to the thiolase family
SLNHY_RS12675	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS12705	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLNHY_RS12715	COG0163	prenyltransferase activity
SLNHY_RS12720	COG4257	antibiotic catabolic process
SLNHY_RS12725	COG0110	maltose O-acetyltransferase activity
SLNHY_RS12730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SLNHY_RS12735	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SLNHY_RS12770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SLNHY_RS12790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SLNHY_RS12795	COG1333	cytochrome c biogenesis protein
SLNHY_RS12815	COG0406	alpha-ribazole phosphatase activity
SLNHY_RS12820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SLNHY_RS12860	COG1073	alpha beta
SLNHY_RS12865	COG3537	Alpha-1,2-mannosidase
SLNHY_RS12870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLNHY_RS12895	COG3973	AAA domain
SLNHY_RS12905	COG0431	NADPH-dependent FMN reductase
SLNHY_RS12930	COG1742	UPF0060 membrane protein
SLNHY_RS12955	COG0018	arginyl-trna synthetase
SLNHY_RS12960	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SLNHY_RS12965	COG0477	Major facilitator Superfamily
SLNHY_RS12985	COG1690	Belongs to the RtcB family
SLNHY_RS13020	COG0515	serine threonine protein kinase
SLNHY_RS13020	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLNHY_RS13025	COG0113	porphobilinogen synthase activity
SLNHY_RS13030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SLNHY_RS13030	COG1648	precorrin-2 dehydrogenase activity
SLNHY_RS13035	COG0181	hydroxymethylbilane synthase activity
SLNHY_RS13040	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SLNHY_RS13045	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SLNHY_RS13095	COG0123	including yeast histone deacetylase and acetoin utilization protein
SLNHY_RS13100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLNHY_RS13120	COG0180	Tryptophanyl-tRNA synthetase
SLNHY_RS13125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SLNHY_RS13135	COG0842	Transport permease protein
SLNHY_RS13135	COG1129	ABC transporter
SLNHY_RS13165	COG0129	dihydroxy-acid dehydratase activity
SLNHY_RS13180	COG1082	Xylose isomerase domain protein TIM barrel
SLNHY_RS13185	COG0248	Ppx GppA phosphatase
SLNHY_RS13205	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SLNHY_RS13225	COG3387	PFAM Glycoside hydrolase 15-related
SLNHY_RS13240	COG0667	Aldo Keto reductase
SLNHY_RS13260	COG0673	inositol 2-dehydrogenase activity
SLNHY_RS13265	COG1879	ABC-type sugar transport system periplasmic component
SLNHY_RS13270	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLNHY_RS13275	COG1129	ABC transporter
SLNHY_RS13285	COG1940	carbohydrate kinase activity
SLNHY_RS13305	COG1194	a g-specific adenine glycosylase
SLNHY_RS13310	COG1595	DNA-templated transcription, initiation
SLNHY_RS13320	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS13325	COG2205	protein histidine kinase activity
SLNHY_RS13345	COG0739	heme binding
SLNHY_RS13370	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SLNHY_RS13390	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SLNHY_RS13400	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SLNHY_RS13405	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SLNHY_RS13430	COG1660	Displays ATPase and GTPase activities
SLNHY_RS13435	COG2197	response regulator
SLNHY_RS13450	COG0649	NAD binding
SLNHY_RS13475	COG1174	glycine betaine transport
SLNHY_RS13480	COG1174	glycine betaine transport
SLNHY_RS13485	COG1125	glycine betaine transport
SLNHY_RS13485	COG0517	IMP dehydrogenase activity
SLNHY_RS13490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SLNHY_RS13500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SLNHY_RS13520	COG0302	gtp cyclohydrolase
SLNHY_RS13535	COG0037	tRNA processing
SLNHY_RS13545	COG2027	D-alanyl-D-alanine carboxypeptidase
SLNHY_RS13550	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SLNHY_RS13560	COG0586	Pfam SNARE associated Golgi protein
SLNHY_RS13565	COG0789	Transcriptional regulator
SLNHY_RS13570	COG0076	glutamate decarboxylase activity
SLNHY_RS13590	COG2318	DinB family
SLNHY_RS13595	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS13620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SLNHY_RS13625	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SLNHY_RS13630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SLNHY_RS13635	COG0254	rRNA binding
SLNHY_RS13645	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SLNHY_RS13685	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLNHY_RS13685	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLNHY_RS13735	COG1674	ftsk spoiiie
SLNHY_RS13815	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SLNHY_RS13820	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SLNHY_RS13825	COG1754	DNA topoisomerase type I activity
SLNHY_RS13825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SLNHY_RS13830	COG2890	protein-(glutamine-N5) methyltransferase activity
SLNHY_RS13840	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SLNHY_RS13845	COG2172	sigma factor antagonist activity
SLNHY_RS13850	COG1366	Belongs to the anti-sigma-factor antagonist family
SLNHY_RS13855	COG1111	helicase
SLNHY_RS13855	COG1205	dead DEAH box helicase
SLNHY_RS13910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLNHY_RS13915	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SLNHY_RS13925	COG2267	carboxylic ester hydrolase activity
SLNHY_RS13955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLNHY_RS13965	COG0251	oxidation-reduction process
SLNHY_RS13975	COG0003	Pfam Anion-transporting ATPase
SLNHY_RS13985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLNHY_RS13995	COG1408	metallophosphoesterase
SLNHY_RS14045	COG0546	phosphoglycolate phosphatase activity
SLNHY_RS14090	COG0515	serine threonine protein kinase
SLNHY_RS14090	COG2815	serine threonine protein kinase
SLNHY_RS14135	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS14145	COG4175	Glycine betaine
SLNHY_RS14145	COG0517	IMP dehydrogenase activity
SLNHY_RS14150	COG4176	ABC-type proline glycine betaine transport system permease component
SLNHY_RS14220	COG2255	four-way junction helicase activity
SLNHY_RS14225	COG1609	Transcriptional regulator
SLNHY_RS14245	COG2304	oxidoreductase activity
SLNHY_RS14275	COG0438	transferase activity, transferring glycosyl groups
SLNHY_RS14280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SLNHY_RS14290	COG0728	peptidoglycan biosynthetic process
SLNHY_RS14380	COG1595	DNA-templated transcription, initiation
SLNHY_RS14395	COG2815	serine threonine protein kinase
SLNHY_RS14395	COG0515	serine threonine protein kinase
SLNHY_RS14405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SLNHY_RS14410	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SLNHY_RS14425	COG1802	Transcriptional regulator
SLNHY_RS14430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLNHY_RS14460	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SLNHY_RS14475	COG1131	(ABC) transporter
SLNHY_RS14480	COG3559	Exporter of polyketide antibiotics
SLNHY_RS14485	COG2124	cytochrome p450
SLNHY_RS14495	COG3844	kynureninase activity
SLNHY_RS14500	COG3483	tryptophan 2,3-dioxygenase activity
SLNHY_RS14515	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
SLNHY_RS14530	COG0191	fructose-bisphosphate aldolase activity
SLNHY_RS14535	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SLNHY_RS14550	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SLNHY_RS14605	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLNHY_RS14620	COG1595	DNA-templated transcription, initiation
SLNHY_RS14635	COG0542	response to heat
SLNHY_RS14685	COG0789	Transcriptional regulator
SLNHY_RS14690	COG0484	heat shock protein binding
SLNHY_RS14695	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SLNHY_RS14700	COG0443	Heat shock 70 kDa protein
SLNHY_RS14705	COG0247	lactate metabolic process
SLNHY_RS14705	COG2181	nitrate reductase activity
SLNHY_RS14715	COG1595	DNA-templated transcription, initiation
SLNHY_RS14725	COG0596	Alpha beta hydrolase
SLNHY_RS14750	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SLNHY_RS14755	COG0717	Belongs to the dCTP deaminase family
SLNHY_RS14850	COG0798	PFAM Bile acid sodium symporter
SLNHY_RS14860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLNHY_RS14865	COG0640	Transcriptional regulator
SLNHY_RS14875	COG0673	inositol 2-dehydrogenase activity
SLNHY_RS14885	COG0604	alcohol dehydrogenase
SLNHY_RS14885	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS14885	COG3321	synthase
SLNHY_RS14890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLNHY_RS14895	COG0586	Pfam SNARE associated Golgi protein
SLNHY_RS14900	COG0028	Belongs to the TPP enzyme family
SLNHY_RS14900	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
SLNHY_RS14910	COG0477	Major facilitator Superfamily
SLNHY_RS14925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SLNHY_RS14930	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SLNHY_RS14935	COG3002	Belongs to the UPF0753 family
SLNHY_RS14940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SLNHY_RS14945	COG0573	inorganic phosphate transmembrane transporter activity
SLNHY_RS14950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SLNHY_RS14955	COG0640	Transcriptional regulator
SLNHY_RS14960	COG0640	Transcriptional regulator
SLNHY_RS14980	COG0640	Transcriptional regulator
SLNHY_RS14990	COG0516	GMP reductase activity
SLNHY_RS14990	COG0517	IMP dehydrogenase activity
SLNHY_RS15000	COG0589	response to stress
SLNHY_RS15030	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SLNHY_RS15070	COG4109	DRTGG domain
SLNHY_RS15100	COG0725	ABC transporter, periplasmic molybdate-binding protein
SLNHY_RS15120	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SLNHY_RS15125	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SLNHY_RS15130	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SLNHY_RS15205	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS15210	COG0477	Major facilitator Superfamily
SLNHY_RS15250	COG2815	serine threonine protein kinase
SLNHY_RS15250	COG0515	serine threonine protein kinase
SLNHY_RS15280	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS15285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLNHY_RS15290	COG4521	taurine ABC transporter
SLNHY_RS15325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SLNHY_RS15355	COG5000	phosphorelay sensor kinase activity
SLNHY_RS15370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLNHY_RS15385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLNHY_RS15435	COG1131	(ABC) transporter
SLNHY_RS15450	COG0494	nUDIX hydrolase
SLNHY_RS15455	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SLNHY_RS15460	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SLNHY_RS15465	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SLNHY_RS15470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLNHY_RS15500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLNHY_RS15515	COG1120	ATPase activity
SLNHY_RS15520	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLNHY_RS15525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLNHY_RS15530	COG1132	(ABC) transporter
SLNHY_RS15535	COG1132	(ABC) transporter
SLNHY_RS15550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLNHY_RS15560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLNHY_RS15565	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SLNHY_RS15570	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SLNHY_RS15590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SLNHY_RS15605	COG1366	Belongs to the anti-sigma-factor antagonist family
SLNHY_RS15610	COG1191	sigma factor activity
SLNHY_RS15625	COG2770	Histidine kinase
SLNHY_RS15625	COG2208	phosphoserine phosphatase activity
SLNHY_RS15665	COG1073	alpha beta
SLNHY_RS15680	COG0702	epimerase
SLNHY_RS15710	COG1278	Cold shock
SLNHY_RS15760	COG2326	polyphosphate kinase activity
SLNHY_RS15800	COG1024	Enoyl-CoA hydratase
SLNHY_RS15800	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SLNHY_RS15825	COG3629	intracellular signal transduction
SLNHY_RS15865	COG0640	Transcriptional regulator
SLNHY_RS15870	COG0346	lactoylglutathione lyase activity
SLNHY_RS15875	COG3896	Chloramphenicol phosphotransferase-like protein
SLNHY_RS15950	COG2197	response regulator
SLNHY_RS15965	COG1733	regulation of RNA biosynthetic process
SLNHY_RS15975	COG0702	epimerase
SLNHY_RS15980	COG0747	negative chemotaxis
SLNHY_RS16000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SLNHY_RS16005	COG2755	lipolytic protein G-D-S-L family
SLNHY_RS16010	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS16015	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS16070	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLNHY_RS16075	COG2304	oxidoreductase activity
SLNHY_RS16085	COG0583	DNA-binding transcription factor activity
SLNHY_RS16095	COG2267	carboxylic ester hydrolase activity
SLNHY_RS16100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLNHY_RS16130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLNHY_RS16135	COG1993	acr, cog1993
SLNHY_RS16140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SLNHY_RS16175	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS16180	COG5002	protein histidine kinase activity
SLNHY_RS16200	COG2186	Transcriptional regulator
SLNHY_RS16260	COG1362	aminopeptidase activity
SLNHY_RS16265	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS16280	COG1741	Belongs to the pirin family
SLNHY_RS16305	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SLNHY_RS16315	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLNHY_RS16320	COG0022	dehydrogenase e1 component
SLNHY_RS16340	COG0515	serine threonine protein kinase
SLNHY_RS16345	COG0515	serine threonine protein kinase
SLNHY_RS16395	COG1522	sequence-specific DNA binding
SLNHY_RS16400	COG1309	transcriptional regulator
SLNHY_RS16405	COG1250	3-hydroxyacyl-CoA dehydrogenase
SLNHY_RS16435	COG3396	Phenylacetate-CoA oxygenase
SLNHY_RS16440	COG3460	Phenylacetate-CoA oxygenase
SLNHY_RS16445	COG3396	Phenylacetate-CoA oxygenase
SLNHY_RS16450	COG2151	metal-sulfur cluster biosynthetic enzyme
SLNHY_RS16455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SLNHY_RS16475	COG1733	regulation of RNA biosynthetic process
SLNHY_RS16480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SLNHY_RS16490	COG1716	ATPase activity
SLNHY_RS16495	COG1716	ATPase activity
SLNHY_RS16515	COG0515	serine threonine protein kinase
SLNHY_RS16520	COG3764	Sortase (surface protein transpeptidase)
SLNHY_RS16525	COG3764	Sortase (surface protein transpeptidase)
SLNHY_RS16545	COG0457	Tetratricopeptide repeat
SLNHY_RS16545	COG0705	Rhomboid family
SLNHY_RS16570	COG0515	serine threonine protein kinase
SLNHY_RS16585	COG2208	phosphoserine phosphatase activity
SLNHY_RS16585	COG2172	sigma factor antagonist activity
SLNHY_RS16585	COG1366	Belongs to the anti-sigma-factor antagonist family
SLNHY_RS16595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SLNHY_RS16615	COG1857	crispr-associated protein
SLNHY_RS16670	COG2186	Transcriptional regulator
SLNHY_RS16730	COG0582	viral genome integration into host DNA
SLNHY_RS16745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SLNHY_RS16750	COG0187	DNA topoisomerase II activity
SLNHY_RS16755	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SLNHY_RS16760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SLNHY_RS16765	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SLNHY_RS16770	COG0592	DNA-directed DNA polymerase activity
SLNHY_RS16775	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SLNHY_RS16780	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SLNHY_RS16790	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SLNHY_RS16795	COG0706	membrane insertase activity
SLNHY_RS16805	COG0357	Ribosomal RNA small subunit methyltransferase G
SLNHY_RS16810	COG1192	Involved in chromosome partitioning
SLNHY_RS16825	COG3118	belongs to the thioredoxin family
SLNHY_RS16830	COG0492	ferredoxin-NADP+ reductase activity
SLNHY_RS16840	COG1595	DNA-templated transcription, initiation
SLNHY_RS16845	COG0515	serine threonine protein kinase
SLNHY_RS16845	COG2815	serine threonine protein kinase
SLNHY_RS16860	COG0617	tRNA 3'-terminal CCA addition
SLNHY_RS16885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SLNHY_RS16910	COG0360	Binds together with S18 to 16S ribosomal RNA
SLNHY_RS16915	COG0629	single-stranded DNA binding
SLNHY_RS16920	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SLNHY_RS16925	COG0359	binds to the 23S rRNA
SLNHY_RS16935	COG0305	Participates in initiation and elongation during chromosome replication
SLNHY_RS16960	COG1535	isochorismatase
SLNHY_RS16960	COG3433	isochorismatase activity
SLNHY_RS16965	COG0393	Putative heavy-metal-binding
SLNHY_RS16975	COG2318	DinB family
SLNHY_RS16995	COG2814	Major facilitator Superfamily
SLNHY_RS17015	COG0626	cystathionine gamma-synthase activity
SLNHY_RS17020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SLNHY_RS17025	COG1950	PFAM Membrane protein of
SLNHY_RS17030	COG0662	Cupin 2, conserved barrel domain protein
SLNHY_RS17055	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SLNHY_RS17120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SLNHY_RS17125	COG1609	Transcriptional regulator
SLNHY_RS17130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SLNHY_RS17135	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS17140	COG1271	oxidase subunit
SLNHY_RS17145	COG1294	oxidase, subunit
SLNHY_RS17150	COG4988	ABC transporter
SLNHY_RS17160	COG0739	heme binding
SLNHY_RS17165	COG0561	phosphatase activity
SLNHY_RS17180	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SLNHY_RS17200	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
SLNHY_RS17205	COG1131	(ABC) transporter
SLNHY_RS17225	COG0561	phosphatase activity
SLNHY_RS17230	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SLNHY_RS17240	COG2837	iron assimilation
SLNHY_RS17255	COG1999	signal sequence binding
SLNHY_RS17295	COG0601	transmembrane transport
SLNHY_RS17300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLNHY_RS17315	COG1940	carbohydrate kinase activity
SLNHY_RS17335	COG0006	proline dipeptidase activity
SLNHY_RS17350	COG0653	protein targeting
SLNHY_RS17365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLNHY_RS17390	COG4129	membrane
SLNHY_RS17405	COG1595	DNA-templated transcription, initiation
SLNHY_RS17420	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS17510	COG2188	Transcriptional regulator
SLNHY_RS17540	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS17545	COG2205	protein histidine kinase activity
SLNHY_RS17555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SLNHY_RS17555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SLNHY_RS17570	COG2353	YceI-like domain
SLNHY_RS17590	COG1191	sigma factor activity
SLNHY_RS17595	COG1191	sigma factor activity
SLNHY_RS17635	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SLNHY_RS17665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS17675	COG0431	NADPH-dependent FMN reductase
SLNHY_RS17685	COG0583	DNA-binding transcription factor activity
SLNHY_RS17700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SLNHY_RS17710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLNHY_RS17715	COG4948	Mandelate Racemase Muconate Lactonizing
SLNHY_RS17735	COG0601	transmembrane transport
SLNHY_RS17740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SLNHY_RS17745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SLNHY_RS17785	COG1136	(ABC) transporter
SLNHY_RS17800	COG2318	DinB family
SLNHY_RS17815	COG2409	Drug exporters of the RND superfamily
SLNHY_RS17835	COG0640	Transcriptional regulator
SLNHY_RS17840	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS17850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS17860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SLNHY_RS17905	COG1414	Transcriptional regulator
SLNHY_RS17915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLNHY_RS17920	COG4948	Mandelate Racemase Muconate Lactonizing
SLNHY_RS17930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SLNHY_RS17935	COG0583	DNA-binding transcription factor activity
SLNHY_RS17940	COG0697	spore germination
SLNHY_RS17945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SLNHY_RS17965	COG0151	Belongs to the GarS family
SLNHY_RS17995	COG2175	clavaminate synthase activity
SLNHY_RS18015	COG0151	Belongs to the GarS family
SLNHY_RS18030	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SLNHY_RS18035	COG3119	arylsulfatase activity
SLNHY_RS18040	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SLNHY_RS18050	COG2197	response regulator
SLNHY_RS18085	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SLNHY_RS18090	COG0047	phosphoribosylformylglycinamidine synthase activity
SLNHY_RS18095	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SLNHY_RS18100	COG2318	DinB family
SLNHY_RS18105	COG1309	transcriptional regulator
SLNHY_RS18135	COG3119	arylsulfatase activity
SLNHY_RS18145	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SLNHY_RS18175	COG1643	Atp-dependent helicase
SLNHY_RS18220	COG0513	Belongs to the DEAD box helicase family
SLNHY_RS18225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS18240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLNHY_RS18245	COG1454	alcohol dehydrogenase
SLNHY_RS18280	COG0515	serine threonine protein kinase
SLNHY_RS18285	COG1216	Glycosyl transferase, family 2
SLNHY_RS18285	COG0438	transferase activity, transferring glycosyl groups
SLNHY_RS18355	COG2835	tetraacyldisaccharide 4'-kinase activity
SLNHY_RS18375	COG4981	capsule polysaccharide biosynthetic process
SLNHY_RS18430	COG0667	Aldo Keto reductase
SLNHY_RS18440	COG2339	peptidase activity
SLNHY_RS18450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SLNHY_RS18455	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SLNHY_RS18460	COG0579	oxidoreductase
SLNHY_RS18480	COG0366	Alpha amylase catalytic
SLNHY_RS18480	COG1470	cell adhesion involved in biofilm formation
SLNHY_RS18490	COG1252	NADH dehydrogenase
SLNHY_RS18585	COG0739	heme binding
SLNHY_RS18585	COG0741	lytic transglycosylase activity
SLNHY_RS18585	COG1196	nuclear chromosome segregation
SLNHY_RS18590	COG0671	phosphoesterase, PA-phosphatase related
SLNHY_RS18595	COG0277	FAD linked oxidase domain protein
SLNHY_RS18615	COG1937	Protein conserved in bacteria
SLNHY_RS18625	COG0306	phosphate transporter
SLNHY_RS18630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SLNHY_RS18645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SLNHY_RS18650	COG0406	alpha-ribazole phosphatase activity
SLNHY_RS18650	COG0494	nUDIX hydrolase
SLNHY_RS18660	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SLNHY_RS18675	COG1725	Transcriptional regulator
SLNHY_RS18680	COG0456	acetyltransferase
SLNHY_RS18690	COG0737	Belongs to the 5'-nucleotidase family
SLNHY_RS18695	COG0823	Involved in the tonB-independent uptake of proteins
SLNHY_RS18700	COG2205	protein histidine kinase activity
SLNHY_RS18705	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS18710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SLNHY_RS18720	COG1609	Transcriptional regulator
SLNHY_RS18725	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS18750	COG2897	thiosulfate sulfurtransferase activity
SLNHY_RS18770	COG3485	protocatechuate 3,4-dioxygenase
SLNHY_RS18775	COG0735	belongs to the Fur family
SLNHY_RS18780	COG0354	folic acid binding
SLNHY_RS18785	COG1490	D-aminoacyl-tRNA deacylase activity
SLNHY_RS18800	COG4552	Acetyltransferase involved in intracellular survival and related
SLNHY_RS18810	COG1309	transcriptional regulator
SLNHY_RS18825	COG2188	Transcriptional regulator
SLNHY_RS18880	COG2226	methyltransferase
SLNHY_RS18920	COG0438	transferase activity, transferring glycosyl groups
SLNHY_RS18960	COG0588	phosphoglycerate mutase activity
SLNHY_RS18995	COG2124	cytochrome p450
SLNHY_RS19010	COG5002	protein histidine kinase activity
SLNHY_RS19025	COG1329	Transcriptional regulator
SLNHY_RS19030	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SLNHY_RS19035	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SLNHY_RS19045	COG0215	cysteine-tRNA ligase activity
SLNHY_RS19065	COG4585	Histidine kinase
SLNHY_RS19070	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SLNHY_RS19080	COG3842	ATPase activity
SLNHY_RS19090	COG3655	Transcriptional regulator
SLNHY_RS19115	COG1366	Belongs to the anti-sigma-factor antagonist family
SLNHY_RS19120	COG1366	Belongs to the anti-sigma-factor antagonist family
SLNHY_RS19125	COG2172	sigma factor antagonist activity
SLNHY_RS19135	COG2770	Histidine kinase
SLNHY_RS19135	COG2208	phosphoserine phosphatase activity
SLNHY_RS19155	COG2409	Drug exporters of the RND superfamily
SLNHY_RS19175	COG2197	response regulator
SLNHY_RS19180	COG1301	dicarboxylic acid transport
SLNHY_RS19185	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS19205	COG1053	succinate dehydrogenase
SLNHY_RS19210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SLNHY_RS19265	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SLNHY_RS19290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SLNHY_RS19325	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SLNHY_RS19330	COG0463	Glycosyl transferase, family 2
SLNHY_RS19345	COG1278	Cold shock
SLNHY_RS19350	COG0459	protein refolding
SLNHY_RS19365	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SLNHY_RS19410	COG3973	AAA domain
SLNHY_RS19425	COG1061	Type III restriction enzyme res subunit
SLNHY_RS19445	COG3473	Maleate cis-trans isomerase
SLNHY_RS19450	COG0179	Fumarylacetoacetate (FAA) hydrolase
SLNHY_RS19470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SLNHY_RS19490	COG0546	phosphoglycolate phosphatase activity
SLNHY_RS19500	COG1278	Cold shock
SLNHY_RS19505	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SLNHY_RS19510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SLNHY_RS19520	COG2814	Major facilitator Superfamily
SLNHY_RS19570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SLNHY_RS19590	COG2252	PERMEase
SLNHY_RS19615	COG0667	Aldo Keto reductase
SLNHY_RS19630	COG1716	ATPase activity
SLNHY_RS19630	COG1131	(ABC) transporter
SLNHY_RS19630	COG0842	Transport permease protein
SLNHY_RS19640	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SLNHY_RS19645	COG0277	FAD linked oxidase domain protein
SLNHY_RS19645	COG0247	lactate metabolic process
SLNHY_RS19675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SLNHY_RS19685	COG5006	permease, DMT superfamily
SLNHY_RS19710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLNHY_RS19725	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS19745	COG0259	pyridoxamine-phosphate oxidase activity
SLNHY_RS19750	COG0596	Alpha beta hydrolase
SLNHY_RS19760	COG4821	SIS domain
SLNHY_RS19805	COG3345	alpha-galactosidase
SLNHY_RS19850	COG0488	(ABC) transporter
SLNHY_RS19855	COG2072	flavoprotein involved in K transport
SLNHY_RS19865	COG0259	pyridoxamine-phosphate oxidase activity
SLNHY_RS19880	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SLNHY_RS19880	COG0515	serine threonine protein kinase
SLNHY_RS19905	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SLNHY_RS19930	COG1686	Belongs to the peptidase S11 family
SLNHY_RS19940	COG0386	Belongs to the glutathione peroxidase family
SLNHY_RS19945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SLNHY_RS19960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLNHY_RS20000	COG0454	-acetyltransferase
SLNHY_RS20015	COG2986	histidine ammonia-lyase
SLNHY_RS20020	COG2986	histidine ammonia-lyase
SLNHY_RS20050	COG3384	dioxygenase
SLNHY_RS20055	COG1247	-acetyltransferase
SLNHY_RS20070	COG1376	ErfK ybiS ycfS ynhG family protein
SLNHY_RS20100	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SLNHY_RS20115	COG3263	regulation of cellular component size
SLNHY_RS20125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SLNHY_RS20130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SLNHY_RS20140	COG0315	cyclic pyranopterin monophosphate synthase activity
SLNHY_RS20145	COG0315	cyclic pyranopterin monophosphate synthase activity
SLNHY_RS20145	COG0521	Mo-molybdopterin cofactor biosynthetic process
SLNHY_RS20150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLNHY_RS20165	COG3537	Alpha-1,2-mannosidase
SLNHY_RS20200	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS20205	COG0477	Major facilitator Superfamily
SLNHY_RS20220	COG0736	holo-[acyl-carrier-protein] synthase activity
SLNHY_RS20250	COG4989	oxidoreductase activity
SLNHY_RS20260	COG0708	Exodeoxyribonuclease III
SLNHY_RS20270	COG2072	flavoprotein involved in K transport
SLNHY_RS20275	COG2267	carboxylic ester hydrolase activity
SLNHY_RS20280	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS20290	COG4946	Tricorn protease homolog
SLNHY_RS20290	COG0793	Belongs to the peptidase S41A family
SLNHY_RS20300	COG2409	Drug exporters of the RND superfamily
SLNHY_RS20310	COG0310	cobalt ion transport
SLNHY_RS20320	COG1122	ATPase activity
SLNHY_RS20325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLNHY_RS20330	COG0789	Transcriptional regulator
SLNHY_RS20355	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SLNHY_RS20385	COG0084	hydrolase, TatD family'
SLNHY_RS20390	COG3584	3D domain protein
SLNHY_RS20390	COG3583	domain protein
SLNHY_RS20395	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SLNHY_RS20400	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SLNHY_RS20405	COG0488	(ABC) transporter
SLNHY_RS20455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SLNHY_RS20465	COG2197	response regulator
SLNHY_RS20475	COG4106	trans-aconitate 2-methyltransferase activity
SLNHY_RS20485	COG1309	transcriptional regulator
SLNHY_RS20495	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SLNHY_RS20505	COG0193	aminoacyl-tRNA hydrolase activity
SLNHY_RS20510	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SLNHY_RS20515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SLNHY_RS20520	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SLNHY_RS20530	COG4585	Histidine kinase
SLNHY_RS20535	COG4585	Histidine kinase
SLNHY_RS20560	COG1316	TRANSCRIPTIONal
SLNHY_RS20565	COG2814	Major facilitator Superfamily
SLNHY_RS20570	COG1136	(ABC) transporter
SLNHY_RS20575	COG0577	efflux transmembrane transporter activity
SLNHY_RS20595	COG0561	phosphatase activity
SLNHY_RS20605	COG0142	geranyltranstransferase activity
SLNHY_RS20700	COG2234	aminopeptidase activity
SLNHY_RS20700	COG4935	Belongs to the peptidase S8 family
SLNHY_RS20710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SLNHY_RS20715	COG0702	epimerase
SLNHY_RS20730	COG1013	pyruvate-flavodoxin oxidoreductase activity
SLNHY_RS20735	COG0674	pyruvate-flavodoxin oxidoreductase activity
SLNHY_RS20735	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SLNHY_RS20755	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLNHY_RS20760	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLNHY_RS20765	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLNHY_RS20770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SLNHY_RS20775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SLNHY_RS20780	COG0839	Belongs to the complex I subunit 6 family
SLNHY_RS20785	COG0713	ATP synthesis coupled electron transport
SLNHY_RS20790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SLNHY_RS20800	COG1007	ATP synthesis coupled electron transport
SLNHY_RS20805	COG0501	Belongs to the peptidase M48B family
SLNHY_RS20810	COG3304	Inner membrane component domain
SLNHY_RS20820	COG2261	transglycosylase associated protein
SLNHY_RS20830	COG1666	GTP binding
SLNHY_RS20865	COG0702	epimerase
SLNHY_RS20885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SLNHY_RS20890	COG2030	dehydratase
SLNHY_RS20900	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SLNHY_RS20905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLNHY_RS20910	COG0436	Aminotransferase
SLNHY_RS20920	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SLNHY_RS20925	COG0250	Participates in transcription elongation, termination and antitermination
SLNHY_RS20935	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SLNHY_RS20940	COG0081	regulation of translation
SLNHY_RS20955	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SLNHY_RS20960	COG0222	ribosome binding
SLNHY_RS20965	COG0085	RNA polymerase activity
SLNHY_RS20970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SLNHY_RS21010	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SLNHY_RS21015	COG0049	tRNA binding
SLNHY_RS21020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SLNHY_RS21025	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SLNHY_RS21030	COG0051	transcription antitermination factor activity, RNA binding
SLNHY_RS21035	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SLNHY_RS21040	COG0088	Forms part of the polypeptide exit tunnel
SLNHY_RS21045	COG0089	rRNA binding
SLNHY_RS21050	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SLNHY_RS21055	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SLNHY_RS21060	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SLNHY_RS21065	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SLNHY_RS21070	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SLNHY_RS21075	COG0255	Belongs to the universal ribosomal protein uL29 family
SLNHY_RS21080	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SLNHY_RS21085	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SLNHY_RS21090	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SLNHY_RS21095	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SLNHY_RS21100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SLNHY_RS21105	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SLNHY_RS21110	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SLNHY_RS21115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SLNHY_RS21120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SLNHY_RS21130	COG0200	Binds to the 23S rRNA
SLNHY_RS21140	COG0563	adenylate kinase activity
SLNHY_RS21150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SLNHY_RS21155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SLNHY_RS21160	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SLNHY_RS21165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SLNHY_RS21170	COG0202	RNA polymerase activity
SLNHY_RS21175	COG0203	ribosomal protein L17
SLNHY_RS21180	COG0101	tRNA pseudouridine synthase activity
SLNHY_RS21190	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SLNHY_RS21195	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SLNHY_RS21200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLNHY_RS21210	COG1072	(Pantothenic acid kinase))
SLNHY_RS21215	COG0736	holo-[acyl-carrier-protein] synthase activity
SLNHY_RS21220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SLNHY_RS21220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SLNHY_RS21225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SLNHY_RS21235	COG0802	atpase or kinase
SLNHY_RS21260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SLNHY_RS21280	COG4941	Belongs to the sigma-70 factor family
SLNHY_RS21290	COG0726	polysaccharide deacetylase
SLNHY_RS21300	COG0459	protein refolding
SLNHY_RS21310	COG4221	oxidoreductase activity
SLNHY_RS21320	COG0583	DNA-binding transcription factor activity
SLNHY_RS21330	COG2197	response regulator
SLNHY_RS21335	COG1595	DNA-templated transcription, initiation
SLNHY_RS21345	COG0516	GMP reductase activity
SLNHY_RS21360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SLNHY_RS21380	COG2815	serine threonine protein kinase
SLNHY_RS21380	COG0515	serine threonine protein kinase
SLNHY_RS21395	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS21420	COG0519	Catalyzes the synthesis of GMP from XMP
SLNHY_RS21420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SLNHY_RS21470	COG2197	response regulator
SLNHY_RS21480	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS21485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLNHY_RS21505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLNHY_RS21515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLNHY_RS21535	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS21550	COG0583	DNA-binding transcription factor activity
SLNHY_RS21560	COG2197	response regulator
SLNHY_RS21595	COG0739	heme binding
SLNHY_RS21605	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLNHY_RS21620	COG0714	Associated with various cellular activities
SLNHY_RS21630	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SLNHY_RS21705	COG1222	aaa ATPase
SLNHY_RS21735	COG0045	succinate-CoA ligase (ADP-forming) activity
SLNHY_RS21765	COG0138	bifunctional purine biosynthesis protein purh
SLNHY_RS21775	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SLNHY_RS21790	COG1695	Transcriptional regulator
SLNHY_RS21800	COG0039	L-malate dehydrogenase activity
SLNHY_RS21825	COG3920	Histidine kinase
SLNHY_RS21840	COG3119	arylsulfatase activity
SLNHY_RS21845	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SLNHY_RS21850	COG1819	glycosyl
SLNHY_RS21855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SLNHY_RS21860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLNHY_RS21865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLNHY_RS21870	COG0180	Tryptophanyl-tRNA synthetase
SLNHY_RS21895	COG1295	ribonuclease BN
SLNHY_RS21900	COG1686	Belongs to the peptidase S11 family
SLNHY_RS21910	COG1408	metallophosphoesterase
SLNHY_RS21920	COG2409	Drug exporters of the RND superfamily
SLNHY_RS21975	COG2009	succinate dehydrogenase
SLNHY_RS21985	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SLNHY_RS22020	COG1595	DNA-templated transcription, initiation
SLNHY_RS22050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SLNHY_RS22060	COG1216	Glycosyl transferase, family 2
SLNHY_RS22075	COG2089	acid synthase
SLNHY_RS22085	COG1473	amidohydrolase
SLNHY_RS22085	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SLNHY_RS22090	COG1744	ABC transporter substrate-binding protein PnrA-like
SLNHY_RS22095	COG3845	ABC transporter
SLNHY_RS22100	COG4603	Belongs to the binding-protein-dependent transport system permease family
SLNHY_RS22105	COG1079	Belongs to the binding-protein-dependent transport system permease family
SLNHY_RS22140	COG2814	Major facilitator Superfamily
SLNHY_RS22145	COG0583	DNA-binding transcription factor activity
SLNHY_RS22155	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SLNHY_RS22180	COG2205	protein histidine kinase activity
SLNHY_RS22185	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS22190	COG1595	DNA-templated transcription, initiation
SLNHY_RS22205	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS22210	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS22230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SLNHY_RS22255	COG4770	biotin carboxylase activity
SLNHY_RS22265	COG0424	maF-like protein
SLNHY_RS22275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLNHY_RS22285	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SLNHY_RS22290	COG1024	Enoyl-CoA hydratase
SLNHY_RS22300	COG0515	serine threonine protein kinase
SLNHY_RS22310	COG1132	(ABC) transporter
SLNHY_RS22315	COG1132	(ABC) transporter
SLNHY_RS22330	COG2197	response regulator
SLNHY_RS22335	COG2986	histidine ammonia-lyase
SLNHY_RS22365	COG1064	alcohol dehydrogenase
SLNHY_RS22380	COG1396	sequence-specific DNA binding
SLNHY_RS22385	COG0740	serine-type endopeptidase activity
SLNHY_RS22390	COG0740	serine-type endopeptidase activity
SLNHY_RS22415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SLNHY_RS22445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SLNHY_RS22460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SLNHY_RS22470	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SLNHY_RS22480	COG3629	intracellular signal transduction
SLNHY_RS22480	COG3903	Transcriptional regulator
SLNHY_RS22485	COG0596	Alpha beta hydrolase
SLNHY_RS22495	COG0667	Aldo Keto reductase
SLNHY_RS22545	COG4249	Peptidase C14 caspase catalytic subunit p20
SLNHY_RS22545	COG2319	Wd-40 repeat
SLNHY_RS22565	COG2508	Transcriptional regulator
SLNHY_RS22570	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS22575	COG0367	asparagine synthase
SLNHY_RS22580	COG0477	Major facilitator Superfamily
SLNHY_RS22585	COG2050	protein possibly involved in aromatic compounds catabolism
SLNHY_RS22595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLNHY_RS22610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLNHY_RS22615	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS22640	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SLNHY_RS22675	COG3629	intracellular signal transduction
SLNHY_RS22675	COG3903	Transcriptional regulator
SLNHY_RS22685	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS22720	COG3239	Fatty acid desaturase
SLNHY_RS22725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLNHY_RS22730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLNHY_RS22735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLNHY_RS22745	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS22750	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SLNHY_RS22760	COG0243	molybdopterin cofactor binding
SLNHY_RS22760	COG0243	molybdopterin cofactor binding
SLNHY_RS22800	COG1331	Highly conserved protein containing a thioredoxin domain
SLNHY_RS22815	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SLNHY_RS22870	COG2894	cell division
SLNHY_RS22910	COG2885	chlorophyll binding
SLNHY_RS22945	COG1472	Belongs to the glycosyl hydrolase 3 family
SLNHY_RS22950	COG2318	DinB family
SLNHY_RS22960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SLNHY_RS22965	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SLNHY_RS22990	COG1946	Acyl-CoA thioesterase
SLNHY_RS23040	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS23065	COG1295	ribonuclease BN
SLNHY_RS23065	COG1959	2 iron, 2 sulfur cluster binding
SLNHY_RS23080	COG1472	Belongs to the glycosyl hydrolase 3 family
SLNHY_RS23090	COG1609	Transcriptional regulator
SLNHY_RS23095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SLNHY_RS23135	COG3718	enzyme involved in inositol metabolism
SLNHY_RS23140	COG3962	Belongs to the TPP enzyme family
SLNHY_RS23160	COG1309	transcriptional regulator
SLNHY_RS23165	COG1879	ABC-type sugar transport system periplasmic component
SLNHY_RS23170	COG1129	ABC transporter
SLNHY_RS23210	COG2755	lipolytic protein G-D-S-L family
SLNHY_RS23225	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS23235	COG1309	transcriptional regulator
SLNHY_RS23310	COG2205	protein histidine kinase activity
SLNHY_RS23340	COG1309	transcriptional regulator
SLNHY_RS23345	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS23350	COG5002	protein histidine kinase activity
SLNHY_RS23365	COG0477	Major facilitator Superfamily
SLNHY_RS23390	COG1819	glycosyl
SLNHY_RS23395	COG1132	(ABC) transporter
SLNHY_RS23400	COG2755	lipolytic protein G-D-S-L family
SLNHY_RS23420	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SLNHY_RS23420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLNHY_RS23425	COG2124	cytochrome p450
SLNHY_RS23465	COG0367	asparagine synthase
SLNHY_RS23475	COG2197	response regulator
SLNHY_RS23525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLNHY_RS23565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLNHY_RS23590	COG0154	amidase activity
SLNHY_RS23600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SLNHY_RS23615	COG1595	DNA-templated transcription, initiation
SLNHY_RS23660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SLNHY_RS23685	COG0477	Major facilitator Superfamily
SLNHY_RS23720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLNHY_RS23725	COG3938	Belongs to the proline racemase family
SLNHY_RS23730	COG0531	amino acid
SLNHY_RS23785	COG0477	Major facilitator Superfamily
SLNHY_RS23790	COG1733	regulation of RNA biosynthetic process
SLNHY_RS23805	COG2815	serine threonine protein kinase
SLNHY_RS23805	COG0515	serine threonine protein kinase
SLNHY_RS23815	COG0494	nUDIX hydrolase
SLNHY_RS23840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLNHY_RS23850	COG1205	dead DEAH box helicase
SLNHY_RS23850	COG1111	helicase
SLNHY_RS23885	COG0629	single-stranded DNA binding
SLNHY_RS23910	COG2346	COG2346, Truncated hemoglobins
SLNHY_RS23915	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SLNHY_RS23945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SLNHY_RS23955	COG0668	transmembrane transport
SLNHY_RS24010	COG0789	Transcriptional regulator
SLNHY_RS24030	COG4941	Belongs to the sigma-70 factor family
SLNHY_RS24035	COG3795	YCII-related domain
SLNHY_RS24065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SLNHY_RS24070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SLNHY_RS24075	COG1113	amino acid transport
SLNHY_RS24080	COG1268	BioY protein
SLNHY_RS24100	COG4552	Acetyltransferase involved in intracellular survival and related
SLNHY_RS24115	COG3594	Acyltransferase
SLNHY_RS24135	COG0544	peptidyl-prolyl cis-trans isomerase activity
SLNHY_RS24140	COG0740	serine-type endopeptidase activity
SLNHY_RS24145	COG0740	serine-type endopeptidase activity
SLNHY_RS24150	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SLNHY_RS24165	COG0525	valine-tRNA ligase activity
SLNHY_RS24170	COG0285	dihydrofolate synthase activity
SLNHY_RS24180	COG0105	UTP biosynthetic process
SLNHY_RS24185	COG1077	Cell shape determining protein MreB Mrl
SLNHY_RS24200	COG0768	penicillin binding
SLNHY_RS24205	COG0772	Belongs to the SEDS family
SLNHY_RS24235	COG1530	ribonuclease E activity
SLNHY_RS24240	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SLNHY_RS24245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SLNHY_RS24250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SLNHY_RS24265	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SLNHY_RS24275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SLNHY_RS24290	COG0501	Belongs to the peptidase M48B family
SLNHY_RS24295	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SLNHY_RS24305	COG0799	negative regulation of ribosome biogenesis
SLNHY_RS24310	COG0588	phosphoglycerate mutase activity
SLNHY_RS24335	COG0495	leucyl-tRNA aminoacylation
SLNHY_RS24345	COG1307	EDD domain protein, DegV family
SLNHY_RS24355	COG1555	photosystem II stabilization
SLNHY_RS24360	COG1234	tRNA 3'-trailer cleavage
SLNHY_RS24380	COG0268	Binds directly to 16S ribosomal RNA
SLNHY_RS24385	COG0481	GTPase activity
SLNHY_RS24410	COG1420	regulation of RNA biosynthetic process
SLNHY_RS24415	COG0484	heat shock protein binding
SLNHY_RS24420	COG2070	2-Nitropropane dioxygenase
SLNHY_RS24435	COG0793	Belongs to the peptidase S41A family
SLNHY_RS24435	COG4946	Tricorn protease homolog
SLNHY_RS24440	COG0537	adenosine 5'-monophosphoramidase activity
SLNHY_RS24445	COG1234	tRNA 3'-trailer cleavage
SLNHY_RS24450	COG2815	serine threonine protein kinase
SLNHY_RS24450	COG0515	serine threonine protein kinase
SLNHY_RS24460	COG1486	melibiose metabolic process
SLNHY_RS24465	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SLNHY_RS24465	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SLNHY_RS24475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SLNHY_RS24485	COG2315	Protein conserved in bacteria
SLNHY_RS24510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SLNHY_RS24530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLNHY_RS24540	COG2409	Drug exporters of the RND superfamily
SLNHY_RS24545	COG4585	Histidine kinase
SLNHY_RS24550	COG2197	response regulator
SLNHY_RS24560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLNHY_RS24565	COG4608	Belongs to the ABC transporter superfamily
SLNHY_RS24570	COG0444	Belongs to the ABC transporter superfamily
SLNHY_RS24580	COG0747	negative chemotaxis
SLNHY_RS24585	COG2186	Transcriptional regulator
SLNHY_RS24595	COG1381	Involved in DNA repair and RecF pathway recombination
SLNHY_RS24600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SLNHY_RS24610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SLNHY_RS24615	COG1121	(ABC) transporter
SLNHY_RS24625	COG0423	glycine-tRNA ligase activity
SLNHY_RS24635	COG2356	endonuclease I
SLNHY_RS24645	COG0667	Aldo Keto reductase
SLNHY_RS24650	COG0477	Major facilitator Superfamily
SLNHY_RS24660	COG0477	Major facilitator Superfamily
SLNHY_RS24685	COG1846	Transcriptional regulator
SLNHY_RS24695	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SLNHY_RS24705	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLNHY_RS24705	COG0574	Belongs to the PEP-utilizing enzyme family
SLNHY_RS24720	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS24735	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS24740	COG1309	transcriptional regulator
SLNHY_RS24750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLNHY_RS24750	COG2146	nitrite reductase [NAD(P)H] activity
SLNHY_RS24755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLNHY_RS24785	COG0243	molybdopterin cofactor binding
SLNHY_RS24790	COG2949	membrane
SLNHY_RS24800	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SLNHY_RS24810	COG0358	DNA primase activity
SLNHY_RS24815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SLNHY_RS24820	COG2815	serine threonine protein kinase
SLNHY_RS24820	COG0515	serine threonine protein kinase
SLNHY_RS24830	COG0384	phenazine biosynthesis protein PhzF
SLNHY_RS24845	COG1070	Carbohydrate kinase
SLNHY_RS24890	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS24935	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS24960	COG2130	NADP-dependent
SLNHY_RS24970	COG3594	Acyltransferase
SLNHY_RS24990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLNHY_RS24995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SLNHY_RS25000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLNHY_RS25015	COG1741	Belongs to the pirin family
SLNHY_RS25025	COG0789	Transcriptional regulator
SLNHY_RS25030	COG0667	Aldo Keto reductase
SLNHY_RS25045	COG1309	transcriptional regulator
SLNHY_RS25050	COG0477	Major facilitator Superfamily
SLNHY_RS25060	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SLNHY_RS25105	COG1358	cellular component organization or biogenesis
SLNHY_RS25110	COG0586	Pfam SNARE associated Golgi protein
SLNHY_RS25115	COG4585	Histidine kinase
SLNHY_RS25215	COG4122	O-methyltransferase activity
SLNHY_RS25240	COG1127	ABC transporter
SLNHY_RS25250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SLNHY_RS25345	COG3845	ABC transporter
SLNHY_RS25365	COG1309	transcriptional regulator
SLNHY_RS25370	COG0438	transferase activity, transferring glycosyl groups
SLNHY_RS25395	COG0860	N-Acetylmuramoyl-L-alanine amidase
SLNHY_RS25405	COG0477	Major facilitator Superfamily
SLNHY_RS25410	COG2197	response regulator
SLNHY_RS25415	COG4585	Histidine kinase
SLNHY_RS25420	COG2030	dehydratase
SLNHY_RS25435	COG3321	synthase
SLNHY_RS25435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SLNHY_RS25440	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS25465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SLNHY_RS25485	COG3022	response to hydroperoxide
SLNHY_RS25575	COG3540	Alkaline phosphatase
SLNHY_RS25635	COG4221	oxidoreductase activity
SLNHY_RS25645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SLNHY_RS25655	COG1607	acyl-coa hydrolase
SLNHY_RS25690	COG2814	Major facilitator Superfamily
SLNHY_RS25695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SLNHY_RS25735	COG2837	iron assimilation
SLNHY_RS25745	COG1120	ATPase activity
SLNHY_RS25750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLNHY_RS25755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SLNHY_RS25775	COG5398	heme oxygenase
SLNHY_RS25820	COG1994	Peptidase M50
SLNHY_RS25840	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SLNHY_RS25855	COG2814	Major facilitator Superfamily
SLNHY_RS25860	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SLNHY_RS25860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SLNHY_RS25880	COG0174	glutamine synthetase
SLNHY_RS25895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLNHY_RS25905	COG0367	asparagine synthase
SLNHY_RS25925	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS25935	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SLNHY_RS25945	COG0366	Alpha amylase catalytic
SLNHY_RS25955	COG2197	response regulator
SLNHY_RS25960	COG4585	Histidine kinase
SLNHY_RS25970	COG0745	RESPONSE REGULATOR receiver
SLNHY_RS26030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLNHY_RS26045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLNHY_RS26085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SLNHY_RS26090	COG0321	lipoyl(octanoyl) transferase activity
SLNHY_RS26110	COG1090	epimerase
SLNHY_RS26135	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SLNHY_RS26145	COG0508	dehydrogenase complex catalyzes the overall conversion of
SLNHY_RS26150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SLNHY_RS26155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SLNHY_RS26160	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SLNHY_RS26165	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SLNHY_RS26210	COG4585	Histidine kinase
SLNHY_RS26215	COG2197	response regulator
SLNHY_RS26220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SLNHY_RS26230	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SLNHY_RS26250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLNHY_RS26255	COG1104	cysteine desulfurase activity
SLNHY_RS26260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SLNHY_RS26265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SLNHY_RS26275	COG1376	ErfK ybiS ycfS ynhG family protein
SLNHY_RS26285	COG1845	cytochrome c oxidase, subunit III
SLNHY_RS26290	COG2010	Cytochrome c
SLNHY_RS26295	COG0723	plastoquinol--plastocyanin reductase activity
SLNHY_RS26300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SLNHY_RS26305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SLNHY_RS26310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLNHY_RS26340	COG0791	NLP P60 protein
SLNHY_RS26340	COG0741	lytic transglycosylase activity
SLNHY_RS26360	COG0438	transferase activity, transferring glycosyl groups
SLNHY_RS26365	COG1022	Amp-dependent synthetase and ligase
SLNHY_RS26380	COG0003	Pfam Anion-transporting ATPase
SLNHY_RS26390	COG1940	carbohydrate kinase activity
SLNHY_RS26415	COG4585	Histidine kinase
SLNHY_RS26420	COG2197	response regulator
SLNHY_RS26430	COG0205	6-phosphofructokinase activity
SLNHY_RS26445	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SLNHY_RS26450	COG0243	molybdopterin cofactor binding
SLNHY_RS26455	COG2193	ferroxidase activity
SLNHY_RS26460	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SLNHY_RS26465	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SLNHY_RS26470	COG0515	serine threonine protein kinase
SLNHY_RS26470	COG2815	serine threonine protein kinase
SLNHY_RS26475	COG2022	thiamine diphosphate biosynthetic process
SLNHY_RS26495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SLNHY_RS26505	COG0352	thiamine-phosphate diphosphorylase activity
SLNHY_RS26535	COG1309	transcriptional regulator
SLNHY_RS26555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SLNHY_RS26575	COG0714	Associated with various cellular activities
SLNHY_RS26585	COG0275	rRNA processing
SLNHY_RS26600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SLNHY_RS26610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SLNHY_RS26615	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SLNHY_RS26625	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SLNHY_RS26635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SLNHY_RS26650	COG1799	cell septum assembly
SLNHY_RS26665	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SLNHY_RS26675	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SLNHY_RS26735	COG0587	DNA-directed DNA polymerase activity
SLNHY_RS26765	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SLNHY_RS26770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SLNHY_RS26785	COG2197	response regulator
SLNHY_RS26795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SLNHY_RS26800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SLNHY_RS26805	COG0131	Imidazoleglycerol-phosphate dehydratase
SLNHY_RS26810	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SLNHY_RS26815	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SLNHY_RS26820	COG0251	oxidation-reduction process
SLNHY_RS26825	COG0107	imidazoleglycerol-phosphate synthase activity
SLNHY_RS26830	COG2409	Drug exporters of the RND superfamily
SLNHY_RS26840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SLNHY_RS26865	COG0134	indole-3-glycerol-phosphate synthase activity
SLNHY_RS26875	COG0133	tryptophan synthase activity
SLNHY_RS26880	COG0159	tryptophan synthase activity
SLNHY_RS26890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SLNHY_RS26895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLNHY_RS26905	COG0070	glutamate synthase
SLNHY_RS26905	COG0069	glutamate synthase activity
SLNHY_RS26905	COG0067	glutamate synthase
SLNHY_RS26940	COG1470	cell adhesion involved in biofilm formation
SLNHY_RS26940	COG0366	Alpha amylase catalytic
SLNHY_RS26955	COG1605	Chorismate mutase
SLNHY_RS26955	COG0287	Prephenate dehydrogenase
SLNHY_RS26960	COG4566	intracellular signal transduction
SLNHY_RS27035	COG2050	protein possibly involved in aromatic compounds catabolism
SLNHY_RS27060	COG1643	Atp-dependent helicase
SLNHY_RS27065	COG2226	methyltransferase
SLNHY_RS27070	COG0539	negative regulation of cytoplasmic translation
SLNHY_RS27090	COG0237	dephospho-CoA kinase activity
SLNHY_RS27105	COG2226	methyltransferase
SLNHY_RS27130	COG0277	FAD linked oxidase domain protein
SLNHY_RS27185	COG0598	Magnesium transport protein CorA
SLNHY_RS27190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SLNHY_RS27195	COG2313	pseudouridylate synthase activity
SLNHY_RS27200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SLNHY_RS27205	COG0584	glycerophosphoryl diester phosphodiesterase
SLNHY_RS27215	COG0556	nucleotide-excision repair
SLNHY_RS27245	COG0387	Pfam Sodium calcium exchanger
SLNHY_RS27250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SLNHY_RS27265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SLNHY_RS27275	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLNHY_RS27280	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SLNHY_RS27280	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SLNHY_RS27300	COG0322	excinuclease ABC activity
SLNHY_RS27305	COG1660	Displays ATPase and GTPase activities
SLNHY_RS27310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SLNHY_RS27315	COG1481	regulation of sporulation
SLNHY_RS27320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SLNHY_RS27325	COG0126	phosphoglycerate kinase activity
SLNHY_RS27330	COG0149	triose-phosphate isomerase activity
SLNHY_RS27335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SLNHY_RS27345	COG0166	Belongs to the GPI family
SLNHY_RS27355	COG0363	glucosamine-6-phosphate deaminase activity
SLNHY_RS27370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SLNHY_RS27380	COG0109	protoheme IX farnesyltransferase activity
SLNHY_RS27405	COG1131	(ABC) transporter
SLNHY_RS27420	COG0719	Fe-S assembly protein
SLNHY_RS27430	COG0396	ATPase activity
SLNHY_RS27435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SLNHY_RS27440	COG0822	iron-sulfur transferase activity
SLNHY_RS27460	COG2076	Multidrug Resistance protein
SLNHY_RS27465	COG2171	N-acyltransferase activity
SLNHY_RS27480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SLNHY_RS27525	COG2252	PERMEase
SLNHY_RS27540	COG4977	sequence-specific DNA binding
SLNHY_RS27550	COG5285	phytanoyl-CoA dioxygenase
SLNHY_RS27555	COG1917	Cupin 2, conserved barrel domain protein
SLNHY_RS27560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SLNHY_RS27565	COG0456	acetyltransferase
SLNHY_RS27570	COG1104	cysteine desulfurase activity
SLNHY_RS27580	COG0765	amino acid transport
SLNHY_RS27620	COG1797	cobyrinic acid a,c-diamide synthase activity
SLNHY_RS27635	COG1492	cobalamin metabolic process
SLNHY_RS27640	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SLNHY_RS27660	COG0235	Class ii aldolase
SLNHY_RS27680	COG0488	(ABC) transporter
SLNHY_RS27740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SLNHY_RS27750	COG1404	Belongs to the peptidase S8 family
SLNHY_RS27765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SLNHY_RS27770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SLNHY_RS27795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SLNHY_RS27815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SLNHY_RS27825	COG2186	Transcriptional regulator
SLNHY_RS27845	COG3830	Belongs to the UPF0237 family
SLNHY_RS27845	COG0560	Phosphoserine phosphatase
SLNHY_RS27850	COG1716	ATPase activity
SLNHY_RS27850	COG1131	(ABC) transporter
SLNHY_RS27850	COG0842	Transport permease protein
SLNHY_RS27860	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SLNHY_RS27865	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS27870	COG4585	Histidine kinase
SLNHY_RS27875	COG2197	response regulator
SLNHY_RS27885	COG1119	ATPase activity
SLNHY_RS27905	COG1881	PFAM PEBP family protein
SLNHY_RS27915	COG2094	Belongs to the DNA glycosylase MPG family
SLNHY_RS27950	COG0647	UMP catabolic process
SLNHY_RS27955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLNHY_RS27960	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SLNHY_RS27965	COG1120	ATPase activity
SLNHY_RS27985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SLNHY_RS27990	COG0497	DNA recombination
SLNHY_RS28000	COG3387	PFAM Glycoside hydrolase 15-related
SLNHY_RS28005	COG0504	CTP synthase activity
SLNHY_RS28010	COG0494	nUDIX hydrolase
SLNHY_RS28020	COG0686	Belongs to the AlaDH PNT family
SLNHY_RS28035	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SLNHY_RS28040	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SLNHY_RS28045	COG1187	pseudouridine synthase activity
SLNHY_RS28085	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SLNHY_RS28095	COG1160	GTP binding
SLNHY_RS28110	COG0438	transferase activity, transferring glycosyl groups
SLNHY_RS28120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SLNHY_RS28130	COG0671	phosphoesterase, PA-phosphatase related
SLNHY_RS28135	COG0477	Major facilitator Superfamily
SLNHY_RS28140	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS28145	COG1799	cell septum assembly
SLNHY_RS28160	COG0765	amino acid transport
SLNHY_RS28170	COG1126	abc transporter atp-binding protein
SLNHY_RS28175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS28200	COG0587	DNA-directed DNA polymerase activity
SLNHY_RS28235	COG1725	Transcriptional regulator
SLNHY_RS28245	COG2755	lipolytic protein G-D-S-L family
SLNHY_RS28255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SLNHY_RS28265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLNHY_RS28270	COG1879	ABC-type sugar transport system periplasmic component
SLNHY_RS28275	COG1172	Belongs to the binding-protein-dependent transport system permease family
SLNHY_RS28280	COG1129	ABC transporter
SLNHY_RS28290	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS28295	COG1175	transmembrane transport
SLNHY_RS28310	COG1609	Transcriptional regulator
SLNHY_RS28330	COG1278	Cold shock
SLNHY_RS28340	COG2188	Transcriptional regulator
SLNHY_RS28345	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SLNHY_RS28350	COG1309	transcriptional regulator
SLNHY_RS28355	COG0243	molybdopterin cofactor binding
SLNHY_RS28360	COG2851	Citrate transporter
SLNHY_RS28405	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS28430	COG0789	Transcriptional regulator
SLNHY_RS28440	COG3876	Protein conserved in bacteria
SLNHY_RS28450	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS28470	COG2149	membrane
SLNHY_RS28475	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SLNHY_RS28505	COG3265	gluconokinase activity
SLNHY_RS28510	COG2186	Transcriptional regulator
SLNHY_RS28515	COG3012	SEC-C Motif Domain Protein
SLNHY_RS28525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLNHY_RS28530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLNHY_RS28535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS28540	COG1953	Uracil, thiamine, allantoin
SLNHY_RS28570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SLNHY_RS28600	COG0667	Aldo Keto reductase
SLNHY_RS28605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS28615	COG0598	Magnesium transport protein CorA
SLNHY_RS28620	COG0406	alpha-ribazole phosphatase activity
SLNHY_RS28635	COG0215	cysteine-tRNA ligase activity
SLNHY_RS28640	COG1470	cell adhesion involved in biofilm formation
SLNHY_RS28640	COG0366	Alpha amylase catalytic
SLNHY_RS28655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SLNHY_RS28660	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SLNHY_RS28665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SLNHY_RS28670	COG1414	Transcriptional regulator
SLNHY_RS28675	COG1410	methionine synthase
SLNHY_RS28675	COG0646	methionine synthase
SLNHY_RS28680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SLNHY_RS28690	COG2197	response regulator
SLNHY_RS28700	COG1994	Peptidase M50
SLNHY_RS28700	COG0517	IMP dehydrogenase activity
SLNHY_RS28720	COG1222	aaa ATPase
SLNHY_RS28725	COG4122	O-methyltransferase activity
SLNHY_RS28735	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLNHY_RS28740	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLNHY_RS28745	COG1609	Transcriptional regulator
SLNHY_RS28755	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SLNHY_RS28760	COG0545	Peptidyl-prolyl cis-trans isomerase
SLNHY_RS28770	COG2378	regulation of single-species biofilm formation
SLNHY_RS28790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SLNHY_RS28795	COG0805	protein transport
SLNHY_RS28845	COG0564	pseudouridine synthase activity
SLNHY_RS28855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SLNHY_RS28860	COG4175	Glycine betaine
SLNHY_RS28860	COG0517	IMP dehydrogenase activity
SLNHY_RS28875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SLNHY_RS28895	COG0583	DNA-binding transcription factor activity
SLNHY_RS28905	COG1309	transcriptional regulator
SLNHY_RS28955	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SLNHY_RS28960	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SLNHY_RS28965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SLNHY_RS28970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SLNHY_RS28975	COG5002	protein histidine kinase activity
SLNHY_RS28980	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SLNHY_RS28985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SLNHY_RS28985	COG0072	phenylalanine-tRNA ligase activity
SLNHY_RS29010	COG1649	PFAM Uncharacterised BCR, COG1649
SLNHY_RS29020	COG0697	spore germination
SLNHY_RS29035	COG2130	NADP-dependent
SLNHY_RS29040	COG0789	Transcriptional regulator
SLNHY_RS29050	COG0601	transmembrane transport
SLNHY_RS29065	COG4106	trans-aconitate 2-methyltransferase activity
SLNHY_RS29080	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SLNHY_RS29085	COG0346	lactoylglutathione lyase activity
SLNHY_RS29095	COG2226	methyltransferase
SLNHY_RS29120	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SLNHY_RS29130	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SLNHY_RS29135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SLNHY_RS29140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLNHY_RS29145	COG1438	arginine binding
SLNHY_RS29150	COG0385	Bile acid
SLNHY_RS29160	COG0277	FAD linked oxidase domain protein
SLNHY_RS29185	COG3189	MarR family transcriptional regulator
SLNHY_RS29190	COG0137	argininosuccinate synthase activity
SLNHY_RS29195	COG0165	Argininosuccinate lyase
SLNHY_RS29220	COG5650	phosphatidylinositol metabolic process
SLNHY_RS29230	COG0204	Acyl-transferase
SLNHY_RS29230	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS29250	COG3046	protein related to deoxyribodipyrimidine photolyase
SLNHY_RS29265	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SLNHY_RS29270	COG2011	ABC-type metal ion transport system permease component
SLNHY_RS29275	COG1464	Belongs to the NlpA lipoprotein family
SLNHY_RS29290	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SLNHY_RS29295	COG1648	precorrin-2 dehydrogenase activity
SLNHY_RS29295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SLNHY_RS29325	COG2233	PERMEase
SLNHY_RS29335	COG0477	Major facilitator Superfamily
SLNHY_RS29370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SLNHY_RS29435	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SLNHY_RS29455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SLNHY_RS29460	COG1560	Kdo2-lipid A biosynthetic process
SLNHY_RS29465	COG0438	transferase activity, transferring glycosyl groups
SLNHY_RS29475	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SLNHY_RS29480	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SLNHY_RS29485	COG0217	transcriptional regulatory protein
SLNHY_RS29490	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SLNHY_RS29495	COG0632	four-way junction helicase activity
SLNHY_RS29500	COG2255	four-way junction helicase activity
SLNHY_RS29510	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLNHY_RS29515	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SLNHY_RS29520	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SLNHY_RS29530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SLNHY_RS29550	COG1196	nuclear chromosome segregation
SLNHY_RS29555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SLNHY_RS29565	COG0124	histidyl-tRNA synthetase
SLNHY_RS29580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SLNHY_RS29595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SLNHY_RS29600	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SLNHY_RS29610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SLNHY_RS29615	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SLNHY_RS29620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SLNHY_RS29625	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SLNHY_RS29635	COG0006	proline dipeptidase activity
SLNHY_RS29640	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SLNHY_RS29645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SLNHY_RS29655	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SLNHY_RS29660	COG0540	Belongs to the ATCase OTCase family
SLNHY_RS29665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SLNHY_RS29675	COG0505	Belongs to the CarA family
SLNHY_RS29680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SLNHY_RS29685	COG0167	dihydroorotate dehydrogenase activity
SLNHY_RS29690	COG0284	orotidine-5'-phosphate decarboxylase activity
SLNHY_RS29700	COG0194	GDP metabolic process
SLNHY_RS29705	COG1758	RNA polymerase activity
SLNHY_RS29715	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SLNHY_RS29735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SLNHY_RS29760	COG2409	Drug exporters of the RND superfamily
SLNHY_RS29765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SLNHY_RS29770	COG2390	Transcriptional regulator
SLNHY_RS29790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SLNHY_RS29820	COG0702	epimerase
SLNHY_RS29835	COG3201	nicotinamide mononucleotide transporter
SLNHY_RS29840	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLNHY_RS29840	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SLNHY_RS29845	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SLNHY_RS29850	COG0140	phosphoribosyl-ATP diphosphatase activity
SLNHY_RS29855	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SLNHY_RS29905	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS29915	COG1522	sequence-specific DNA binding
SLNHY_RS29925	COG0463	Glycosyl transferase, family 2
SLNHY_RS29940	COG0584	glycerophosphoryl diester phosphodiesterase
SLNHY_RS29950	COG2186	Transcriptional regulator
SLNHY_RS29980	COG0438	transferase activity, transferring glycosyl groups
SLNHY_RS29985	COG1984	allophanate hydrolase subunit 2
SLNHY_RS29990	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SLNHY_RS29995	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SLNHY_RS30000	COG4336	lyase activity
SLNHY_RS30005	COG2814	Major facilitator Superfamily
SLNHY_RS30040	COG2018	Roadblock/LC7 domain
SLNHY_RS30060	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SLNHY_RS30075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLNHY_RS30085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SLNHY_RS30090	COG2190	(PTS) system
SLNHY_RS30115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SLNHY_RS30135	COG1716	ATPase activity
SLNHY_RS30155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SLNHY_RS30165	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SLNHY_RS30165	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SLNHY_RS30235	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SLNHY_RS30240	COG0531	amino acid
SLNHY_RS30250	COG0174	glutamine synthetase
SLNHY_RS30255	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS30265	COG0697	spore germination
SLNHY_RS30305	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SLNHY_RS30320	COG0673	inositol 2-dehydrogenase activity
SLNHY_RS30325	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SLNHY_RS30345	COG1968	undecaprenyl-diphosphatase activity
SLNHY_RS30390	COG0110	maltose O-acetyltransferase activity
SLNHY_RS30405	COG1832	CoA-binding protein
SLNHY_RS30410	COG1739	Uncharacterized protein family UPF0029
SLNHY_RS30420	COG0436	Aminotransferase
SLNHY_RS30430	COG0420	3'-5' exonuclease activity
SLNHY_RS30435	COG0419	ATPase involved in DNA repair
SLNHY_RS30450	COG0626	cystathionine gamma-synthase activity
SLNHY_RS30465	COG0346	lactoylglutathione lyase activity
SLNHY_RS30480	COG2197	response regulator
SLNHY_RS30495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SLNHY_RS30535	COG2723	6-phospho-beta-galactosidase activity
SLNHY_RS30540	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS30545	COG1175	transmembrane transport
SLNHY_RS30550	COG2182	Extracellular solute-binding protein
SLNHY_RS30555	COG1940	carbohydrate kinase activity
SLNHY_RS30575	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SLNHY_RS30580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SLNHY_RS30585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SLNHY_RS30600	COG0791	NLP P60 protein
SLNHY_RS30610	COG1309	transcriptional regulator
SLNHY_RS30625	COG2018	Roadblock/LC7 domain
SLNHY_RS30635	COG1946	Acyl-CoA thioesterase
SLNHY_RS30650	COG1132	(ABC) transporter
SLNHY_RS30670	COG1132	(ABC) transporter
SLNHY_RS30680	COG2072	flavoprotein involved in K transport
SLNHY_RS30685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS30695	COG1116	anion transmembrane transporter activity
SLNHY_RS30700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SLNHY_RS30705	COG0432	Pfam Uncharacterised protein family UPF0047
SLNHY_RS30740	COG1408	metallophosphoesterase
SLNHY_RS30745	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLNHY_RS30760	COG2890	protein-(glutamine-N5) methyltransferase activity
SLNHY_RS30785	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SLNHY_RS30870	COG3285	dna ligase
SLNHY_RS30870	COG1793	dna ligase
SLNHY_RS30900	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS30910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SLNHY_RS30935	COG2610	gluconate transmembrane transporter activity
SLNHY_RS30940	COG0251	oxidation-reduction process
SLNHY_RS30945	COG1414	Transcriptional regulator
SLNHY_RS30965	COG3469	chitinase activity
SLNHY_RS30990	COG3467	pyridoxamine 5'-phosphate
SLNHY_RS30995	COG3387	PFAM Glycoside hydrolase 15-related
SLNHY_RS31035	COG3845	ABC transporter
SLNHY_RS31055	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SLNHY_RS31065	COG3290	protein histidine kinase activity
SLNHY_RS31105	COG0375	protein maturation
SLNHY_RS31110	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SLNHY_RS31125	COG0409	Hydrogenase expression formation protein
SLNHY_RS31130	COG0309	Hydrogenase expression formation protein (HypE)
SLNHY_RS31160	COG1024	Enoyl-CoA hydratase
SLNHY_RS31190	COG0667	Aldo Keto reductase
SLNHY_RS31200	COG1595	DNA-templated transcription, initiation
SLNHY_RS31215	COG2706	6-phosphogluconolactonase activity
SLNHY_RS31230	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SLNHY_RS31235	COG2040	homocysteine
SLNHY_RS31240	COG1902	pentaerythritol trinitrate reductase activity
SLNHY_RS31245	COG0640	Transcriptional regulator
SLNHY_RS31255	COG1309	transcriptional regulator
SLNHY_RS31265	COG0546	phosphoglycolate phosphatase activity
SLNHY_RS31270	COG0671	phosphoesterase, PA-phosphatase related
SLNHY_RS31285	COG1024	Enoyl-CoA hydratase
SLNHY_RS31295	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SLNHY_RS31335	COG1134	teichoic acid transport
SLNHY_RS31350	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SLNHY_RS31360	COG1657	PFAM Prenyltransferase squalene oxidase
SLNHY_RS31380	COG2365	Tyrosine phosphatase family
SLNHY_RS31390	COG2755	lipolytic protein G-D-S-L family
SLNHY_RS31425	COG1063	alcohol dehydrogenase
SLNHY_RS31435	COG0583	DNA-binding transcription factor activity
SLNHY_RS31475	COG0183	Belongs to the thiolase family
SLNHY_RS31535	COG0778	Nitroreductase
SLNHY_RS31580	COG0720	synthase
SLNHY_RS31635	COG1127	ABC transporter
SLNHY_RS31685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLNHY_RS31710	COG0633	Ferredoxin
SLNHY_RS31725	COG2197	response regulator
SLNHY_RS31730	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS31735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS31745	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS31760	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS31805	COG3971	2-oxopent-4-enoate hydratase activity
SLNHY_RS31825	COG0633	Ferredoxin
SLNHY_RS31830	COG2197	response regulator
SLNHY_RS31840	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SLNHY_RS31855	COG0604	alcohol dehydrogenase
SLNHY_RS31860	COG1024	Enoyl-CoA hydratase
SLNHY_RS31865	COG2186	Transcriptional regulator
SLNHY_RS31870	COG0183	Belongs to the thiolase family
SLNHY_RS31875	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLNHY_RS31875	COG1703	isobutyryl-CoA mutase activity
SLNHY_RS31875	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SLNHY_RS31880	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SLNHY_RS31890	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS31900	COG2030	dehydratase
SLNHY_RS31905	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS31910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SLNHY_RS31915	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS31925	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS31930	COG0183	Belongs to the thiolase family
SLNHY_RS31935	COG0427	acetyl-CoA hydrolase
SLNHY_RS31940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SLNHY_RS31945	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS31990	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS32010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SLNHY_RS32060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLNHY_RS32065	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS32075	COG1132	(ABC) transporter
SLNHY_RS32080	COG2814	Major facilitator Superfamily
SLNHY_RS32110	COG0640	Transcriptional regulator
SLNHY_RS32130	COG1309	transcriptional regulator
SLNHY_RS32160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SLNHY_RS32160	COG5322	oxidoreductase activity
SLNHY_RS32165	COG0604	alcohol dehydrogenase
SLNHY_RS32165	COG3321	synthase
SLNHY_RS32180	COG0318	PFAM AMP-dependent synthetase and ligase
SLNHY_RS32205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SLNHY_RS32210	COG0475	glutathione-regulated potassium exporter activity
SLNHY_RS32225	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SLNHY_RS32245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SLNHY_RS32400	COG0714	Associated with various cellular activities
SLNHY_RS32420	COG0454	-acetyltransferase
SLNHY_RS32545	COG0151	Belongs to the GarS family
SLNHY_RS32625	COG1028	Short-chain dehydrogenase reductase Sdr
SLNHY_RS32665	COG4221	oxidoreductase activity
SLNHY_RS32675	COG0339	signal peptide processing
SLNHY_RS32705	COG0667	Aldo Keto reductase
SLNHY_RS32785	COG0105	UTP biosynthetic process
SLNHY_RS32815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SLNHY_RS32830	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SLNHY_RS32845	COG3458	cephalosporin-C deacetylase activity
SLNHY_RS32885	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SLNHY_RS32935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SLNHY_RS32950	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SLNHY_RS32955	COG0121	glutamine amidotransferase
SLNHY_RS32960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SLNHY_RS32975	COG1609	Transcriptional regulator
SLNHY_RS32980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SLNHY_RS32985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SLNHY_RS32990	COG2813	Specifically methylates the guanine in position
SLNHY_RS33010	COG1289	transmembrane transporter activity
SLNHY_RS33020	COG2837	iron assimilation
SLNHY_RS33025	COG0076	glutamate decarboxylase activity
SLNHY_RS33030	COG0542	response to heat
SLNHY_RS33050	COG0477	Major facilitator Superfamily
SLNHY_RS33095	COG0395	ABC-type sugar transport system, permease component
SLNHY_RS33100	COG1175	transmembrane transport
SLNHY_RS33110	COG3250	beta-galactosidase activity
SLNHY_RS33115	COG1609	Transcriptional regulator
SLNHY_RS33125	COG3290	protein histidine kinase activity
SLNHY_RS33135	COG1940	carbohydrate kinase activity
SLNHY_RS33140	COG1309	transcriptional regulator
SLNHY_RS33175	COG1175	transmembrane transport
SLNHY_RS33195	COG1113	amino acid transport
SLNHY_RS33205	COG1174	glycine betaine transport
SLNHY_RS33210	COG1174	glycine betaine transport
SLNHY_RS33235	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SLNHY_RS33235	COG3291	Pkd domain containing protein
SLNHY_RS33265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SLNHY_RS33275	COG0019	diaminopimelate decarboxylase activity
SLNHY_RS33310	COG0596	Alpha beta hydrolase
SLNHY_RS33320	COG0204	Acyl-transferase
SLNHY_RS33330	COG0205	6-phosphofructokinase activity
SLNHY_RS33335	COG3442	glutamine amidotransferase
SLNHY_RS33345	COG0242	peptide deformylase activity
SLNHY_RS33355	COG1960	acyl-CoA dehydrogenase activity
SLNHY_RS33360	COG1012	belongs to the aldehyde dehydrogenase family
SLNHY_RS33370	COG1793	dna ligase
SLNHY_RS33380	COG1335	isochorismatase
SLNHY_RS33425	COG1595	DNA-templated transcription, initiation
SLNHY_RS33440	COG0477	Major facilitator Superfamily
SLNHY_RS33450	COG0242	peptide deformylase activity
SLNHY_RS33465	COG0309	Hydrogenase expression formation protein (HypE)