locus-tag	class	description
G3260_RS00080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3260_RS00165	COG3261	NADH dehydrogenase
G3260_RS00165	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
G3260_RS00170	COG0651	ATP synthesis coupled electron transport
G3260_RS00180	COG0650	Formate hydrogenlyase subunit 4
G3260_RS00190	COG3260	NADH ubiquinone oxidoreductase 20
G3260_RS00225	COG0659	secondary active sulfate transmembrane transporter activity
G3260_RS00235	COG2824	Alkylphosphonate utilization operon protein PhnA
G3260_RS00320	COG2176	DNA-directed DNA polymerase activity
G3260_RS00325	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G3260_RS00360	COG0641	radical SAM
G3260_RS00420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3260_RS00420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3260_RS00435	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3260_RS00465	COG3387	PFAM Glycoside hydrolase 15-related
G3260_RS00470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G3260_RS00480	COG0252	asparaginase activity
G3260_RS00500	COG2124	cytochrome p450
G3260_RS00605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3260_RS00645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3260_RS00700	COG2826	transposase and inactivated derivatives, IS30 family
G3260_RS00705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3260_RS00710	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G3260_RS00710	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G3260_RS00715	COG2192	nodulation
G3260_RS00790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G3260_RS00805	COG3293	Transposase
G3260_RS00825	COG0789	Transcriptional regulator
G3260_RS00845	COG0583	DNA-binding transcription factor activity
G3260_RS00900	COG0604	alcohol dehydrogenase
G3260_RS00930	COG0539	negative regulation of cytoplasmic translation
G3260_RS00965	COG0187	DNA topoisomerase II activity
G3260_RS00975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3260_RS01005	COG2197	response regulator
G3260_RS01010	COG4585	Histidine kinase
G3260_RS01020	COG0473	3-isopropylmalate dehydrogenase activity
G3260_RS01025	COG0596	Alpha beta hydrolase
G3260_RS01040	COG1562	ergosterol biosynthetic process
G3260_RS01055	COG2267	carboxylic ester hydrolase activity
G3260_RS01100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3260_RS01120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3260_RS01160	COG1960	acyl-CoA dehydrogenase activity
G3260_RS01175	COG0300	oxidoreductase activity
G3260_RS01175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3260_RS01175	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS01175	COG3321	synthase
G3260_RS01175	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS01185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3260_RS01185	COG0574	Belongs to the PEP-utilizing enzyme family
G3260_RS01190	COG3634	alkyl hydroperoxide reductase activity
G3260_RS01195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3260_RS01270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3260_RS01290	COG0328	RNA-DNA hybrid ribonuclease activity
G3260_RS01305	COG1021	2,3-dihydroxybenzoate-AMP ligase
G3260_RS01310	COG2124	cytochrome p450
G3260_RS01315	COG0367	asparagine synthase
G3260_RS01340	COG2226	methyltransferase
G3260_RS01340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3260_RS01340	COG3433	isochorismatase activity
G3260_RS01375	COG4171	peptide transport system, permease
G3260_RS01390	COG0583	DNA-binding transcription factor activity
G3260_RS01400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3260_RS01405	COG0477	Major facilitator Superfamily
G3260_RS01420	COG0604	alcohol dehydrogenase
G3260_RS01425	COG1309	transcriptional regulator
G3260_RS01460	COG0583	DNA-binding transcription factor activity
G3260_RS01470	COG2186	Transcriptional regulator
G3260_RS01475	COG2807	transmembrane transport
G3260_RS01480	COG0076	glutamate decarboxylase activity
G3260_RS01485	COG1482	cell wall glycoprotein biosynthetic process
G3260_RS01490	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS01510	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS01515	COG0656	L-ascorbic acid biosynthetic process
G3260_RS01585	COG1960	acyl-CoA dehydrogenase activity
G3260_RS01590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3260_RS01595	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3260_RS01615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3260_RS01625	COG0697	spore germination
G3260_RS01630	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G3260_RS01705	COG0697	spore germination
G3260_RS01710	COG0583	DNA-binding transcription factor activity
G3260_RS01720	COG2267	carboxylic ester hydrolase activity
G3260_RS01770	COG0783	Belongs to the Dps family
G3260_RS01790	COG0402	S-adenosylhomocysteine deaminase activity
G3260_RS01800	COG0583	DNA-binding transcription factor activity
G3260_RS01810	COG0753	catalase activity
G3260_RS01830	COG1959	2 iron, 2 sulfur cluster binding
G3260_RS01845	COG0330	HflC and HflK could
G3260_RS01860	COG0583	DNA-binding transcription factor activity
G3260_RS01885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G3260_RS01965	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS01980	COG0009	L-threonylcarbamoyladenylate synthase
G3260_RS02015	COG1216	Glycosyl transferase, family 2
G3260_RS02090	COG1472	Belongs to the glycosyl hydrolase 3 family
G3260_RS02115	COG1191	sigma factor activity
G3260_RS02155	COG2186	Transcriptional regulator
G3260_RS02160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3260_RS02170	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G3260_RS02170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3260_RS02185	COG2188	Transcriptional regulator
G3260_RS02190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3260_RS02200	COG3467	pyridoxamine 5'-phosphate
G3260_RS02215	COG1505	serine-type exopeptidase activity
G3260_RS02230	COG2755	lipolytic protein G-D-S-L family
G3260_RS02240	COG1120	ATPase activity
G3260_RS02245	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3260_RS02250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3260_RS02260	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS02265	COG1169	isochorismate synthase
G3260_RS02270	COG1021	2,3-dihydroxybenzoate-AMP ligase
G3260_RS02275	COG1535	isochorismatase
G3260_RS02275	COG3433	isochorismatase activity
G3260_RS02280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3260_RS02285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3260_RS02285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3260_RS02310	COG2382	esterase
G3260_RS02345	COG1486	melibiose metabolic process
G3260_RS02350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3260_RS02355	COG0395	ABC-type sugar transport system, permease component
G3260_RS02365	COG2182	Extracellular solute-binding protein
G3260_RS02380	COG0768	penicillin binding
G3260_RS02385	COG0583	DNA-binding transcription factor activity
G3260_RS02395	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS02425	COG0598	Magnesium transport protein CorA
G3260_RS02445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3260_RS02465	COG0745	RESPONSE REGULATOR receiver
G3260_RS02500	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3260_RS02550	COG4566	intracellular signal transduction
G3260_RS02570	COG1051	belongs to the nudix hydrolase family
G3260_RS02585	COG2255	four-way junction helicase activity
G3260_RS02635	COG1175	transmembrane transport
G3260_RS02640	COG0395	ABC-type sugar transport system, permease component
G3260_RS02645	COG0366	Alpha amylase catalytic
G3260_RS02675	COG0488	(ABC) transporter
G3260_RS02690	COG0477	Major facilitator Superfamily
G3260_RS02730	COG0494	nUDIX hydrolase
G3260_RS02740	COG1902	pentaerythritol trinitrate reductase activity
G3260_RS02740	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3260_RS02750	COG0442	prolyl-tRNA aminoacylation
G3260_RS02775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3260_RS02780	COG2368	4-hydroxyphenylacetate
G3260_RS02790	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G3260_RS02795	COG0477	Major facilitator Superfamily
G3260_RS02825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G3260_RS02845	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS02860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3260_RS02890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3260_RS02900	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G3260_RS02920	COG0477	Major facilitator Superfamily
G3260_RS02940	COG2124	cytochrome p450
G3260_RS02945	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G3260_RS02950	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G3260_RS02965	COG0367	asparagine synthase
G3260_RS03000	COG2807	transmembrane transport
G3260_RS03030	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS03035	COG0477	Major facilitator Superfamily
G3260_RS03050	COG2124	cytochrome p450
G3260_RS03065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3260_RS03075	COG2271	Major facilitator Superfamily
G3260_RS03080	COG0596	Alpha beta hydrolase
G3260_RS03085	COG3903	Transcriptional regulator
G3260_RS03085	COG3629	intracellular signal transduction
G3260_RS03100	COG3655	Transcriptional regulator
G3260_RS03160	COG1674	ftsk spoiiie
G3260_RS03165	COG1404	Belongs to the peptidase S8 family
G3260_RS03190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3260_RS03215	COG4266	Belongs to the allantoicase family
G3260_RS03230	COG0477	Major facilitator Superfamily
G3260_RS03240	COG3971	2-oxopent-4-enoate hydratase activity
G3260_RS03245	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G3260_RS03250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3260_RS03265	COG1917	Cupin 2, conserved barrel domain protein
G3260_RS03275	COG0583	DNA-binding transcription factor activity
G3260_RS03290	COG0395	ABC-type sugar transport system, permease component
G3260_RS03295	COG1175	transmembrane transport
G3260_RS03330	COG3185	4-Hydroxyphenylpyruvate dioxygenase
G3260_RS03345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3260_RS03355	COG0517	IMP dehydrogenase activity
G3260_RS03370	COG0523	cobalamin synthesis protein
G3260_RS03375	COG0402	S-adenosylhomocysteine deaminase activity
G3260_RS03380	COG2233	PERMEase
G3260_RS03390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3260_RS03405	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G3260_RS03420	COG0277	FAD linked oxidase domain protein
G3260_RS03425	COG0596	Alpha beta hydrolase
G3260_RS03435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3260_RS03500	COG0673	inositol 2-dehydrogenase activity
G3260_RS03505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3260_RS03515	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G3260_RS03525	COG0713	ATP synthesis coupled electron transport
G3260_RS03530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G3260_RS03535	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3260_RS03540	COG1007	ATP synthesis coupled electron transport
G3260_RS03560	COG1316	TRANSCRIPTIONal
G3260_RS03565	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G3260_RS03570	COG0640	Transcriptional regulator
G3260_RS03575	COG2261	transglycosylase associated protein
G3260_RS03620	COG4106	trans-aconitate 2-methyltransferase activity
G3260_RS03625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3260_RS03655	COG0477	Major facilitator Superfamily
G3260_RS03660	COG0583	DNA-binding transcription factor activity
G3260_RS03670	COG2318	DinB family
G3260_RS03680	COG2264	protein methyltransferase activity
G3260_RS03690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3260_RS03690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3260_RS03695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3260_RS03705	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G3260_RS03710	COG1917	Cupin 2, conserved barrel domain protein
G3260_RS03720	COG0640	Transcriptional regulator
G3260_RS03725	COG0500	methyltransferase
G3260_RS03745	COG2264	protein methyltransferase activity
G3260_RS03770	COG0667	Aldo Keto reductase
G3260_RS03800	COG1819	glycosyl
G3260_RS03815	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G3260_RS03820	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
G3260_RS03830	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G3260_RS03840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3260_RS03855	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS03860	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G3260_RS03865	COG0745	RESPONSE REGULATOR receiver
G3260_RS03890	COG2197	response regulator
G3260_RS03895	COG1819	glycosyl
G3260_RS03905	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
G3260_RS03940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3260_RS03950	COG0655	NAD(P)H dehydrogenase (quinone) activity
G3260_RS03965	COG2197	response regulator
G3260_RS04115	COG1819	glycosyl
G3260_RS04130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3260_RS04145	COG0477	Major facilitator Superfamily
G3260_RS04150	COG0671	phosphoesterase, PA-phosphatase related
G3260_RS04155	COG2186	Transcriptional regulator
G3260_RS04160	COG0626	cystathionine gamma-synthase activity
G3260_RS04165	COG1757	Na H antiporter
G3260_RS04180	COG2376	Dihydroxyacetone kinase
G3260_RS04185	COG1461	Dihydroxyacetone kinase
G3260_RS04200	COG2124	cytochrome p450
G3260_RS04215	COG4585	Histidine kinase
G3260_RS04230	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G3260_RS04235	COG0463	Glycosyl transferase, family 2
G3260_RS04255	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS04265	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G3260_RS04270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3260_RS04275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3260_RS04285	COG0464	growth
G3260_RS04295	COG1349	DNA-binding transcription factor activity
G3260_RS04305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G3260_RS04325	COG1940	carbohydrate kinase activity
G3260_RS04330	COG0738	Major facilitator superfamily
G3260_RS04335	COG0596	Alpha beta hydrolase
G3260_RS04355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3260_RS04360	COG1660	Displays ATPase and GTPase activities
G3260_RS04385	COG1609	Transcriptional regulator
G3260_RS04390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G3260_RS04395	COG2309	aminopeptidase activity
G3260_RS04405	COG2814	Major facilitator Superfamily
G3260_RS04430	COG1335	isochorismatase
G3260_RS04435	COG0596	Alpha beta hydrolase
G3260_RS04470	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G3260_RS04495	COG0367	asparagine synthase
G3260_RS04520	COG0584	glycerophosphoryl diester phosphodiesterase
G3260_RS04545	COG1960	acyl-CoA dehydrogenase activity
G3260_RS04565	COG0242	peptide deformylase activity
G3260_RS04575	COG3442	glutamine amidotransferase
G3260_RS04590	COG0693	protein deglycase activity
G3260_RS04595	COG0842	Transport permease protein
G3260_RS04610	COG1881	PFAM PEBP family protein
G3260_RS04615	COG0586	Pfam SNARE associated Golgi protein
G3260_RS04620	COG4585	Histidine kinase
G3260_RS04645	COG0204	Acyl-transferase
G3260_RS04660	COG0829	nickel cation binding
G3260_RS04665	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G3260_RS04675	COG0804	urea catabolic process
G3260_RS04680	COG0832	Belongs to the urease beta subunit family
G3260_RS04685	COG0831	urea catabolic process
G3260_RS04690	COG1309	transcriptional regulator
G3260_RS04695	COG2234	aminopeptidase activity
G3260_RS04695	COG4935	Belongs to the peptidase S8 family
G3260_RS04705	COG0740	serine-type endopeptidase activity
G3260_RS04730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G3260_RS04735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3260_RS04740	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G3260_RS04795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G3260_RS04810	COG1940	carbohydrate kinase activity
G3260_RS04815	COG2188	Transcriptional regulator
G3260_RS04820	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS04825	COG1595	DNA-templated transcription, initiation
G3260_RS04860	COG0419	ATPase involved in DNA repair
G3260_RS04865	COG0420	3'-5' exonuclease activity
G3260_RS04870	COG1739	Uncharacterized protein family UPF0029
G3260_RS04875	COG1832	CoA-binding protein
G3260_RS04900	COG0110	maltose O-acetyltransferase activity
G3260_RS04930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3260_RS04940	COG1968	undecaprenyl-diphosphatase activity
G3260_RS04985	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G3260_RS04995	COG2318	DinB family
G3260_RS05005	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G3260_RS05035	COG4974	Belongs to the 'phage' integrase family
G3260_RS05055	COG1518	maintenance of DNA repeat elements
G3260_RS05090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3260_RS05095	COG3629	intracellular signal transduction
G3260_RS05095	COG3903	Transcriptional regulator
G3260_RS05115	COG2124	cytochrome p450
G3260_RS05155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G3260_RS05195	COG0477	Major facilitator Superfamily
G3260_RS05270	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G3260_RS05270	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G3260_RS05280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G3260_RS05300	COG1716	ATPase activity
G3260_RS05320	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G3260_RS05350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3260_RS05355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3260_RS05370	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
G3260_RS05375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3260_RS05425	COG4336	lyase activity
G3260_RS05485	COG1024	Enoyl-CoA hydratase
G3260_RS05505	COG0531	amino acid
G3260_RS05515	COG2070	2-Nitropropane dioxygenase
G3260_RS05520	COG0515	serine threonine protein kinase
G3260_RS05525	COG1960	acyl-CoA dehydrogenase activity
G3260_RS05530	COG1473	amidohydrolase
G3260_RS05550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3260_RS05580	COG2315	Protein conserved in bacteria
G3260_RS05585	COG3030	protein affecting phage T7 exclusion by the F plasmid
G3260_RS05590	COG0463	Glycosyl transferase, family 2
G3260_RS05630	COG1960	acyl-CoA dehydrogenase activity
G3260_RS05645	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3260_RS05645	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3260_RS05665	COG0542	response to heat
G3260_RS05680	COG0798	PFAM Bile acid sodium symporter
G3260_RS05705	COG3655	Transcriptional regulator
G3260_RS05750	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G3260_RS05750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G3260_RS05775	COG2409	Drug exporters of the RND superfamily
G3260_RS05805	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G3260_RS05810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3260_RS05815	COG0156	8-amino-7-oxononanoate synthase activity
G3260_RS05820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3260_RS05830	COG1960	acyl-CoA dehydrogenase activity
G3260_RS05840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3260_RS05845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3260_RS05850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3260_RS05865	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS05870	COG3629	intracellular signal transduction
G3260_RS05900	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G3260_RS05905	COG0140	phosphoribosyl-ATP diphosphatase activity
G3260_RS05910	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G3260_RS05915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G3260_RS05915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G3260_RS05920	COG3201	nicotinamide mononucleotide transporter
G3260_RS05935	COG0738	Major facilitator superfamily
G3260_RS05940	COG2233	PERMEase
G3260_RS05960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3260_RS05990	COG0475	glutathione-regulated potassium exporter activity
G3260_RS06000	COG2390	Transcriptional regulator
G3260_RS06005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G3260_RS06015	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G3260_RS06030	COG2814	Major facilitator Superfamily
G3260_RS06060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G3260_RS06070	COG1758	RNA polymerase activity
G3260_RS06075	COG0194	GDP metabolic process
G3260_RS06085	COG0284	orotidine-5'-phosphate decarboxylase activity
G3260_RS06090	COG0167	dihydroorotate dehydrogenase activity
G3260_RS06095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G3260_RS06100	COG0505	Belongs to the CarA family
G3260_RS06110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G3260_RS06115	COG0540	Belongs to the ATCase OTCase family
G3260_RS06120	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G3260_RS06130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3260_RS06135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G3260_RS06140	COG0006	proline dipeptidase activity
G3260_RS06150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G3260_RS06155	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G3260_RS06160	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G3260_RS06165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3260_RS06175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G3260_RS06180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G3260_RS06195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G3260_RS06215	COG0124	histidyl-tRNA synthetase
G3260_RS06225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G3260_RS06230	COG1196	nuclear chromosome segregation
G3260_RS06235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3260_RS06240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G3260_RS06245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3260_RS06250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3260_RS06260	COG2255	four-way junction helicase activity
G3260_RS06265	COG0632	four-way junction helicase activity
G3260_RS06270	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G3260_RS06275	COG0217	transcriptional regulatory protein
G3260_RS06280	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
G3260_RS06285	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
G3260_RS06295	COG0438	transferase activity, transferring glycosyl groups
G3260_RS06300	COG1560	Kdo2-lipid A biosynthetic process
G3260_RS06305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G3260_RS06325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G3260_RS06375	COG0456	acetyltransferase
G3260_RS06385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G3260_RS06385	COG0512	Glutamine amidotransferase of anthranilate synthase
G3260_RS06440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G3260_RS06440	COG1648	precorrin-2 dehydrogenase activity
G3260_RS06445	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G3260_RS06460	COG2011	ABC-type metal ion transport system permease component
G3260_RS06465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G3260_RS06490	COG0584	glycerophosphoryl diester phosphodiesterase
G3260_RS06495	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS06495	COG0204	Acyl-transferase
G3260_RS06500	COG0477	Major facilitator Superfamily
G3260_RS06520	COG0165	Argininosuccinate lyase
G3260_RS06525	COG0137	argininosuccinate synthase activity
G3260_RS06535	COG0385	Bile acid
G3260_RS06540	COG1438	arginine binding
G3260_RS06545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3260_RS06550	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G3260_RS06555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G3260_RS06560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G3260_RS06565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G3260_RS06590	COG0667	Aldo Keto reductase
G3260_RS06625	COG0477	Major facilitator Superfamily
G3260_RS06630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3260_RS06630	COG0072	phenylalanine-tRNA ligase activity
G3260_RS06635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G3260_RS06640	COG5002	protein histidine kinase activity
G3260_RS06645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3260_RS06650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G3260_RS06655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G3260_RS06660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G3260_RS06670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G3260_RS06685	COG1404	Belongs to the peptidase S8 family
G3260_RS06705	COG1595	DNA-templated transcription, initiation
G3260_RS06730	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS06745	COG0531	amino acid
G3260_RS06750	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G3260_RS06770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3260_RS06775	COG4176	ABC-type proline glycine betaine transport system permease component
G3260_RS06780	COG0517	IMP dehydrogenase activity
G3260_RS06780	COG4175	Glycine betaine
G3260_RS06785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3260_RS06810	COG0805	protein transport
G3260_RS06815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3260_RS06840	COG0545	Peptidyl-prolyl cis-trans isomerase
G3260_RS06845	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G3260_RS06855	COG1609	Transcriptional regulator
G3260_RS06860	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G3260_RS06865	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G3260_RS06880	COG4122	O-methyltransferase activity
G3260_RS06885	COG1222	aaa ATPase
G3260_RS06900	COG1994	Peptidase M50
G3260_RS06900	COG0517	IMP dehydrogenase activity
G3260_RS06910	COG2197	response regulator
G3260_RS06915	COG0747	negative chemotaxis
G3260_RS06920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3260_RS06925	COG1410	methionine synthase
G3260_RS06925	COG0646	methionine synthase
G3260_RS06930	COG1414	Transcriptional regulator
G3260_RS06935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G3260_RS06940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3260_RS06945	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G3260_RS06955	COG2186	Transcriptional regulator
G3260_RS06975	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS06980	COG4948	Mandelate Racemase Muconate Lactonizing
G3260_RS06990	COG0215	cysteine-tRNA ligase activity
G3260_RS07010	COG0598	Magnesium transport protein CorA
G3260_RS07020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3260_RS07025	COG0667	Aldo Keto reductase
G3260_RS07055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3260_RS07110	COG0149	triose-phosphate isomerase activity
G3260_RS07115	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G3260_RS07115	COG0517	IMP dehydrogenase activity
G3260_RS07130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3260_RS07140	COG1131	(ABC) transporter
G3260_RS07145	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G3260_RS07210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3260_RS07225	COG0402	S-adenosylhomocysteine deaminase activity
G3260_RS07235	COG1672	PFAM Archaeal ATPase
G3260_RS07235	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G3260_RS07290	COG0456	acetyltransferase
G3260_RS07305	COG1063	alcohol dehydrogenase
G3260_RS07310	COG0156	8-amino-7-oxononanoate synthase activity
G3260_RS07315	COG0583	DNA-binding transcription factor activity
G3260_RS07320	COG0477	Major facilitator Superfamily
G3260_RS07335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3260_RS07410	COG1653	transport
G3260_RS07415	COG1175	transmembrane transport
G3260_RS07420	COG0395	ABC-type sugar transport system, permease component
G3260_RS07445	COG1819	glycosyl
G3260_RS07460	COG0739	heme binding
G3260_RS07465	COG0477	Major facilitator Superfamily
G3260_RS07470	COG3226	Transcriptional regulator
G3260_RS07480	COG1285	pathogenesis
G3260_RS07585	COG1960	acyl-CoA dehydrogenase activity
G3260_RS07600	COG3265	gluconokinase activity
G3260_RS07610	COG2149	membrane
G3260_RS07615	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
G3260_RS07635	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS07640	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS07670	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G3260_RS07675	COG2188	Transcriptional regulator
G3260_RS07705	COG2259	Doxx family
G3260_RS07750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3260_RS07780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G3260_RS07785	COG0587	DNA-directed DNA polymerase activity
G3260_RS07790	COG0745	RESPONSE REGULATOR receiver
G3260_RS07795	COG2205	protein histidine kinase activity
G3260_RS07805	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3260_RS07835	COG1799	cell septum assembly
G3260_RS07840	COG1960	acyl-CoA dehydrogenase activity
G3260_RS07845	COG0477	Major facilitator Superfamily
G3260_RS07855	COG0671	phosphoesterase, PA-phosphatase related
G3260_RS07875	COG0438	transferase activity, transferring glycosyl groups
G3260_RS07880	COG1652	LysM domain
G3260_RS07895	COG1160	GTP binding
G3260_RS07905	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G3260_RS07925	COG1187	pseudouridine synthase activity
G3260_RS07930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G3260_RS07935	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G3260_RS07950	COG0686	Belongs to the AlaDH PNT family
G3260_RS07960	COG0494	nUDIX hydrolase
G3260_RS07965	COG0504	CTP synthase activity
G3260_RS07970	COG3387	PFAM Glycoside hydrolase 15-related
G3260_RS07980	COG0497	DNA recombination
G3260_RS07985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G3260_RS08000	COG1120	ATPase activity
G3260_RS08005	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3260_RS08010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3260_RS08025	COG0647	UMP catabolic process
G3260_RS08035	COG0076	glutamate decarboxylase activity
G3260_RS08040	COG3486	L-lysine 6-monooxygenase (NADPH) activity
G3260_RS08075	COG2094	Belongs to the DNA glycosylase MPG family
G3260_RS08090	COG1881	PFAM PEBP family protein
G3260_RS08115	COG1119	ATPase activity
G3260_RS08130	COG2197	response regulator
G3260_RS08140	COG0842	Transport permease protein
G3260_RS08140	COG1716	ATPase activity
G3260_RS08140	COG1131	(ABC) transporter
G3260_RS08145	COG0560	Phosphoserine phosphatase
G3260_RS08145	COG3830	Belongs to the UPF0237 family
G3260_RS08160	COG2807	transmembrane transport
G3260_RS08165	COG2186	Transcriptional regulator
G3260_RS08170	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G3260_RS08175	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS08180	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G3260_RS08195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G3260_RS08200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3260_RS08230	COG0300	oxidoreductase activity
G3260_RS08245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G3260_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS08300	COG0488	(ABC) transporter
G3260_RS08330	COG1492	cobalamin metabolic process
G3260_RS08345	COG1797	cobyrinic acid a,c-diamide synthase activity
G3260_RS08365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3260_RS08365	COG1017	nitric oxide dioxygenase activity
G3260_RS08390	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G3260_RS08390	COG0825	malonyl-CoA metabolic process
G3260_RS08405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G3260_RS08410	COG1917	Cupin 2, conserved barrel domain protein
G3260_RS08415	COG5285	phytanoyl-CoA dioxygenase
G3260_RS08425	COG1414	Transcriptional regulator
G3260_RS08440	COG2197	response regulator
G3260_RS08445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3260_RS08450	COG1309	transcriptional regulator
G3260_RS08475	COG0768	penicillin binding
G3260_RS08525	COG2171	N-acyltransferase activity
G3260_RS08530	COG3226	Transcriptional regulator
G3260_RS08535	COG2076	Multidrug Resistance protein
G3260_RS08545	COG0822	iron-sulfur transferase activity
G3260_RS08550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G3260_RS08555	COG0396	ATPase activity
G3260_RS08565	COG0719	Fe-S assembly protein
G3260_RS08580	COG1131	(ABC) transporter
G3260_RS08600	COG0109	protoheme IX farnesyltransferase activity
G3260_RS08610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G3260_RS08625	COG0363	glucosamine-6-phosphate deaminase activity
G3260_RS08630	COG0166	Belongs to the GPI family
G3260_RS08640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G3260_RS08645	COG0149	triose-phosphate isomerase activity
G3260_RS08650	COG0126	phosphoglycerate kinase activity
G3260_RS08655	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G3260_RS08660	COG1481	regulation of sporulation
G3260_RS08665	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G3260_RS08670	COG1660	Displays ATPase and GTPase activities
G3260_RS08675	COG0322	excinuclease ABC activity
G3260_RS08690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3260_RS08700	COG2814	Major facilitator Superfamily
G3260_RS08705	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G3260_RS08725	COG0556	nucleotide-excision repair
G3260_RS08730	COG0584	glycerophosphoryl diester phosphodiesterase
G3260_RS08735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G3260_RS08740	COG2814	Major facilitator Superfamily
G3260_RS08765	COG0492	ferredoxin-NADP+ reductase activity
G3260_RS08780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G3260_RS08800	COG0237	dephospho-CoA kinase activity
G3260_RS08815	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3260_RS08820	COG1643	Atp-dependent helicase
G3260_RS08850	COG2050	protein possibly involved in aromatic compounds catabolism
G3260_RS08925	COG0287	Prephenate dehydrogenase
G3260_RS08925	COG1605	Chorismate mutase
G3260_RS08935	COG1397	ADP-ribosylglycohydrolase
G3260_RS08945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3260_RS08950	COG1609	Transcriptional regulator
G3260_RS08955	COG2252	PERMEase
G3260_RS08960	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G3260_RS08965	COG4977	sequence-specific DNA binding
G3260_RS08965	COG1917	Cupin 2, conserved barrel domain protein
G3260_RS08970	COG1470	cell adhesion involved in biofilm formation
G3260_RS08970	COG0366	Alpha amylase catalytic
G3260_RS08990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3260_RS09030	COG1129	ABC transporter
G3260_RS09030	COG0842	Transport permease protein
G3260_RS09050	COG1819	glycosyl
G3260_RS09055	COG0367	asparagine synthase
G3260_RS09075	COG0754	glutathionylspermidine amidase activity
G3260_RS09105	COG2409	Drug exporters of the RND superfamily
G3260_RS09120	COG2345	Transcriptional regulator
G3260_RS09125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3260_RS09135	COG1846	Transcriptional regulator
G3260_RS09145	COG0475	glutathione-regulated potassium exporter activity
G3260_RS09150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3260_RS09155	COG2345	Transcriptional regulator
G3260_RS09160	COG3104	oligopeptide transport
G3260_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS09190	COG0477	Major facilitator Superfamily
G3260_RS09195	COG0439	Biotin carboxylase
G3260_RS09200	COG0511	ligase activity, forming carbon-carbon bonds
G3260_RS09205	COG0825	malonyl-CoA metabolic process
G3260_RS09205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G3260_RS09230	COG2867	negative regulation of translational initiation
G3260_RS09235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3260_RS09240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3260_RS09260	COG2132	Multicopper oxidase
G3260_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS09355	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G3260_RS09375	COG3851	Histidine kinase
G3260_RS09380	COG2197	response regulator
G3260_RS09425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3260_RS09430	COG3321	synthase
G3260_RS09430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3260_RS09450	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS09455	COG3387	PFAM Glycoside hydrolase 15-related
G3260_RS09460	COG1959	2 iron, 2 sulfur cluster binding
G3260_RS09505	COG1357	PFAM Pentapeptide repeats (8 copies)
G3260_RS09515	COG3585	molybdate ion transport
G3260_RS09555	COG3938	Belongs to the proline racemase family
G3260_RS09590	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS09630	COG0067	glutamate synthase
G3260_RS09630	COG0069	glutamate synthase activity
G3260_RS09630	COG0070	glutamate synthase
G3260_RS09645	COG1320	monovalent cation:proton antiporter activity
G3260_RS09670	COG2111	Na H antiporter
G3260_RS09670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G3260_RS09675	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G3260_RS09685	COG0159	tryptophan synthase activity
G3260_RS09690	COG0133	tryptophan synthase activity
G3260_RS09695	COG0134	indole-3-glycerol-phosphate synthase activity
G3260_RS09720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G3260_RS09750	COG1053	succinate dehydrogenase
G3260_RS09755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3260_RS09790	COG0107	imidazoleglycerol-phosphate synthase activity
G3260_RS09795	COG0251	oxidation-reduction process
G3260_RS09800	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G3260_RS09805	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G3260_RS09815	COG0131	Imidazoleglycerol-phosphate dehydratase
G3260_RS09820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3260_RS09825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G3260_RS09840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G3260_RS09870	COG0587	DNA-directed DNA polymerase activity
G3260_RS09905	COG0025	NhaP-type Na H and K H
G3260_RS09920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G3260_RS09930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G3260_RS09935	COG3599	regulation of cell shape
G3260_RS09945	COG1799	cell septum assembly
G3260_RS09960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G3260_RS09965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G3260_RS09970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G3260_RS09980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G3260_RS09985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G3260_RS09995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3260_RS10010	COG0275	rRNA processing
G3260_RS10020	COG0714	Associated with various cellular activities
G3260_RS10040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3260_RS10050	COG1132	(ABC) transporter
G3260_RS10060	COG1309	transcriptional regulator
G3260_RS10080	COG0352	thiamine-phosphate diphosphorylase activity
G3260_RS10090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3260_RS10095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3260_RS10095	COG2022	thiamine diphosphate biosynthetic process
G3260_RS10105	COG2022	thiamine diphosphate biosynthetic process
G3260_RS10110	COG0515	serine threonine protein kinase
G3260_RS10110	COG2815	serine threonine protein kinase
G3260_RS10120	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G3260_RS10125	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3260_RS10130	COG2193	ferroxidase activity
G3260_RS10140	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G3260_RS10155	COG0205	6-phosphofructokinase activity
G3260_RS10160	COG2197	response regulator
G3260_RS10165	COG4585	Histidine kinase
G3260_RS10190	COG1940	carbohydrate kinase activity
G3260_RS10200	COG0003	Pfam Anion-transporting ATPase
G3260_RS10215	COG1022	Amp-dependent synthetase and ligase
G3260_RS10240	COG0791	NLP P60 protein
G3260_RS10265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G3260_RS10275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3260_RS10280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G3260_RS10285	COG0723	plastoquinol--plastocyanin reductase activity
G3260_RS10290	COG2010	Cytochrome c
G3260_RS10295	COG1845	cytochrome c oxidase, subunit III
G3260_RS10305	COG1376	ErfK ybiS ycfS ynhG family protein
G3260_RS10315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3260_RS10320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3260_RS10330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3260_RS10345	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G3260_RS10355	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS10365	COG1309	transcriptional regulator
G3260_RS10370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3260_RS10375	COG2197	response regulator
G3260_RS10380	COG4585	Histidine kinase
G3260_RS10420	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G3260_RS10430	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G3260_RS10435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3260_RS10470	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3260_RS10480	COG0733	neurotransmitter:sodium symporter activity
G3260_RS10485	COG2378	regulation of single-species biofilm formation
G3260_RS10515	COG1309	transcriptional regulator
G3260_RS10520	COG1064	alcohol dehydrogenase
G3260_RS10540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3260_RS10555	COG0531	amino acid
G3260_RS10560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G3260_RS10575	COG2838	Isocitrate dehydrogenase
G3260_RS10620	COG0697	spore germination
G3260_RS10625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3260_RS10640	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G3260_RS10645	COG0321	lipoyl(octanoyl) transferase activity
G3260_RS10665	COG2890	protein-(glutamine-N5) methyltransferase activity
G3260_RS10755	COG1396	sequence-specific DNA binding
G3260_RS10755	COG3800	Transcriptional regulator
G3260_RS10770	COG0300	oxidoreductase activity
G3260_RS10775	COG1309	transcriptional regulator
G3260_RS10780	COG0300	oxidoreductase activity
G3260_RS10785	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS10795	COG2197	response regulator
G3260_RS10825	COG2197	response regulator
G3260_RS10830	COG0366	Alpha amylase catalytic
G3260_RS10840	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G3260_RS10845	COG0174	glutamine synthetase
G3260_RS10850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3260_RS10855	COG0431	NADPH-dependent FMN reductase
G3260_RS10860	COG2340	Cysteine-rich secretory protein family
G3260_RS10880	COG2132	Multicopper oxidase
G3260_RS10885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G3260_RS10885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3260_RS10895	COG2814	Major facilitator Superfamily
G3260_RS10905	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G3260_RS10930	COG1994	Peptidase M50
G3260_RS10965	COG1609	Transcriptional regulator
G3260_RS10975	COG1175	transmembrane transport
G3260_RS10980	COG0395	ABC-type sugar transport system, permease component
G3260_RS11015	COG0789	Transcriptional regulator
G3260_RS11050	COG0463	Glycosyl transferase, family 2
G3260_RS11055	COG0438	transferase activity, transferring glycosyl groups
G3260_RS11070	COG0489	protein tyrosine kinase activity
G3260_RS11125	COG1834	amidinotransferase
G3260_RS11135	COG3795	YCII-related domain
G3260_RS11140	COG1595	DNA-templated transcription, initiation
G3260_RS11145	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3260_RS11155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G3260_RS11160	COG2814	Major facilitator Superfamily
G3260_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS11200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3260_RS11220	COG3851	Histidine kinase
G3260_RS11235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3260_RS11235	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3260_RS11255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G3260_RS11260	COG2318	DinB family
G3260_RS11270	COG3022	response to hydroperoxide
G3260_RS11275	COG0800	Aldolase
G3260_RS11305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G3260_RS11325	COG2030	dehydratase
G3260_RS11330	COG4585	Histidine kinase
G3260_RS11335	COG2197	response regulator
G3260_RS11345	COG0183	Belongs to the thiolase family
G3260_RS11350	COG1960	acyl-CoA dehydrogenase activity
G3260_RS11355	COG3510	cephalosporin hydroxylase
G3260_RS11360	COG0860	N-Acetylmuramoyl-L-alanine amidase
G3260_RS11370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3260_RS11385	COG0438	transferase activity, transferring glycosyl groups
G3260_RS11400	COG1984	allophanate hydrolase subunit 2
G3260_RS11405	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G3260_RS11410	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3260_RS11430	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
G3260_RS11475	COG3845	ABC transporter
G3260_RS11490	COG1309	transcriptional regulator
G3260_RS11495	COG0183	Belongs to the thiolase family
G3260_RS11500	COG2124	cytochrome p450
G3260_RS11525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3260_RS11565	COG3469	chitinase activity
G3260_RS11620	COG1358	cellular component organization or biogenesis
G3260_RS11665	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3260_RS11675	COG0477	Major facilitator Superfamily
G3260_RS11680	COG1309	transcriptional regulator
G3260_RS11695	COG4585	Histidine kinase
G3260_RS11700	COG2197	response regulator
G3260_RS11715	COG0789	Transcriptional regulator
G3260_RS11740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3260_RS11745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3260_RS11750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3260_RS11770	COG1764	response to oxidative stress
G3260_RS11775	COG2130	NADP-dependent
G3260_RS11785	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G3260_RS11790	COG3285	dna ligase
G3260_RS11790	COG1793	dna ligase
G3260_RS11845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G3260_RS11870	COG1070	Carbohydrate kinase
G3260_RS11890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G3260_RS11895	COG0596	Alpha beta hydrolase
G3260_RS11900	COG0358	DNA primase activity
G3260_RS11925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G3260_RS11930	COG0028	Belongs to the TPP enzyme family
G3260_RS11940	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G3260_RS11970	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G3260_RS11975	COG4221	oxidoreductase activity
G3260_RS11985	COG0789	Transcriptional regulator
G3260_RS11990	COG3118	belongs to the thioredoxin family
G3260_RS11995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3260_RS11995	COG0574	Belongs to the PEP-utilizing enzyme family
G3260_RS12040	COG1902	pentaerythritol trinitrate reductase activity
G3260_RS12045	COG0640	Transcriptional regulator
G3260_RS12050	COG2890	protein-(glutamine-N5) methyltransferase activity
G3260_RS12055	COG0423	glycine-tRNA ligase activity
G3260_RS12065	COG1121	(ABC) transporter
G3260_RS12070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G3260_RS12110	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G3260_RS12115	COG1381	Involved in DNA repair and RecF pathway recombination
G3260_RS12155	COG2723	6-phospho-beta-galactosidase activity
G3260_RS12165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3260_RS12195	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G3260_RS12220	COG4977	sequence-specific DNA binding
G3260_RS12225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3260_RS12240	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G3260_RS12250	COG1234	tRNA 3'-trailer cleavage
G3260_RS12255	COG0537	adenosine 5'-monophosphoramidase activity
G3260_RS12270	COG0484	heat shock protein binding
G3260_RS12275	COG1420	regulation of RNA biosynthetic process
G3260_RS12315	COG0481	GTPase activity
G3260_RS12320	COG0268	Binds directly to 16S ribosomal RNA
G3260_RS12330	COG1234	tRNA 3'-trailer cleavage
G3260_RS12340	COG1307	EDD domain protein, DegV family
G3260_RS12350	COG0495	leucyl-tRNA aminoacylation
G3260_RS12375	COG0588	phosphoglycerate mutase activity
G3260_RS12385	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G3260_RS12390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G3260_RS12400	COG0501	Belongs to the peptidase M48B family
G3260_RS12415	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G3260_RS12425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G3260_RS12445	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G3260_RS12450	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G3260_RS12485	COG0772	Belongs to the SEDS family
G3260_RS12505	COG1077	Cell shape determining protein MreB Mrl
G3260_RS12510	COG0105	UTP biosynthetic process
G3260_RS12520	COG0285	dihydrofolate synthase activity
G3260_RS12525	COG1653	transport
G3260_RS12540	COG0525	valine-tRNA ligase activity
G3260_RS12555	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G3260_RS12560	COG0740	serine-type endopeptidase activity
G3260_RS12565	COG0740	serine-type endopeptidase activity
G3260_RS12570	COG0544	peptidyl-prolyl cis-trans isomerase activity
G3260_RS12600	COG1136	(ABC) transporter
G3260_RS12600	COG0577	efflux transmembrane transporter activity
G3260_RS12610	COG4552	Acetyltransferase involved in intracellular survival and related
G3260_RS12635	COG1113	amino acid transport
G3260_RS12640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G3260_RS12645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G3260_RS12675	COG5006	permease, DMT superfamily
G3260_RS12715	COG0668	transmembrane transport
G3260_RS12745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3260_RS12755	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3260_RS12775	COG1136	(ABC) transporter
G3260_RS12800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3260_RS12805	COG1937	Protein conserved in bacteria
G3260_RS12810	COG0730	response to heat
G3260_RS12825	COG0629	single-stranded DNA binding
G3260_RS12880	COG0494	nUDIX hydrolase
G3260_RS12885	COG0181	hydroxymethylbilane synthase activity
G3260_RS12920	COG1088	dTDP-glucose 4,6-dehydratase activity
G3260_RS12925	COG2192	nodulation
G3260_RS12950	COG0438	transferase activity, transferring glycosyl groups
G3260_RS12955	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G3260_RS12960	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G3260_RS12960	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G3260_RS12965	COG0859	PFAM glycosyl transferase family 9
G3260_RS12975	COG0693	protein deglycase activity
G3260_RS12995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G3260_RS13000	COG1993	acr, cog1993
G3260_RS13005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G3260_RS13050	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
G3260_RS13065	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G3260_RS13075	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS13110	COG3962	Belongs to the TPP enzyme family
G3260_RS13115	COG3718	enzyme involved in inositol metabolism
G3260_RS13125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3260_RS13145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G3260_RS13150	COG1609	Transcriptional regulator
G3260_RS13155	COG1129	ABC transporter
G3260_RS13160	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3260_RS13165	COG1879	ABC-type sugar transport system periplasmic component
G3260_RS13170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3260_RS13175	COG1869	D-ribose catabolic process
G3260_RS13190	COG0494	nUDIX hydrolase
G3260_RS13215	COG1946	Acyl-CoA thioesterase
G3260_RS13220	COG1960	acyl-CoA dehydrogenase activity
G3260_RS13225	COG1309	transcriptional regulator
G3260_RS13230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3260_RS13245	COG1960	acyl-CoA dehydrogenase activity
G3260_RS13265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G3260_RS13270	COG0589	response to stress
G3260_RS13280	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G3260_RS13300	COG0739	heme binding
G3260_RS13305	COG3979	chitinase
G3260_RS13320	COG0745	RESPONSE REGULATOR receiver
G3260_RS13350	COG0588	phosphoglycerate mutase activity
G3260_RS13385	COG3300	MHYT domain
G3260_RS13385	COG5001	Diguanylate cyclase
G3260_RS13395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3260_RS13415	COG0154	amidase activity
G3260_RS13445	COG0765	amino acid transport
G3260_RS13450	COG0765	amino acid transport
G3260_RS13455	COG1126	abc transporter atp-binding protein
G3260_RS13545	COG2188	Transcriptional regulator
G3260_RS13550	COG0673	inositol 2-dehydrogenase activity
G3260_RS13555	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3260_RS13560	COG2733	membrane
G3260_RS13570	COG1131	(ABC) transporter
G3260_RS13585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3260_RS13595	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G3260_RS13635	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G3260_RS13645	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G3260_RS13650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G3260_RS13655	COG1263	PTS System
G3260_RS13665	COG0583	DNA-binding transcription factor activity
G3260_RS13700	COG0778	Nitroreductase
G3260_RS13705	COG1263	PTS System
G3260_RS13710	COG1234	tRNA 3'-trailer cleavage
G3260_RS13735	COG1113	amino acid transport
G3260_RS13745	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G3260_RS13755	COG1335	isochorismatase
G3260_RS13790	COG0277	FAD linked oxidase domain protein
G3260_RS13795	COG3185	4-Hydroxyphenylpyruvate dioxygenase
G3260_RS13830	COG0583	DNA-binding transcription factor activity
G3260_RS13840	COG2855	membrane
G3260_RS13850	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3260_RS13865	COG3525	Glycosyl hydrolase, family 20, catalytic domain
G3260_RS13875	COG0395	ABC-type sugar transport system, permease component
G3260_RS13880	COG1175	transmembrane transport
G3260_RS13895	COG0531	amino acid
G3260_RS13900	COG2362	D-Aminopeptidase
G3260_RS13930	COG1678	Uncharacterized ACR, COG1678
G3260_RS13935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G3260_RS13940	COG2188	Transcriptional regulator
G3260_RS13950	COG0776	regulation of translation
G3260_RS13960	COG1278	Cold shock
G3260_RS13965	COG3973	AAA domain
G3260_RS13990	COG1309	transcriptional regulator
G3260_RS13995	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS14010	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G3260_RS14015	COG0793	Belongs to the peptidase S41A family
G3260_RS14025	COG2884	Cell division ATP-binding protein ftsE
G3260_RS14040	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G3260_RS14055	COG0515	serine threonine protein kinase
G3260_RS14060	COG0515	serine threonine protein kinase
G3260_RS14065	COG1716	ATPase activity
G3260_RS14070	COG1653	transport
G3260_RS14075	COG1175	transmembrane transport
G3260_RS14080	COG0395	ABC-type sugar transport system, permease component
G3260_RS14090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3260_RS14110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3260_RS14125	COG1215	transferase activity, transferring glycosyl groups
G3260_RS14145	COG0673	inositol 2-dehydrogenase activity
G3260_RS14150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3260_RS14160	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3260_RS14185	COG2902	Dehydrogenase
G3260_RS14210	COG0653	protein targeting
G3260_RS14225	COG2197	response regulator
G3260_RS14230	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G3260_RS14240	COG0823	Involved in the tonB-independent uptake of proteins
G3260_RS14250	COG0745	RESPONSE REGULATOR receiver
G3260_RS14255	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
G3260_RS14275	COG0714	Associated with various cellular activities
G3260_RS14315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G3260_RS14320	COG2124	cytochrome p450
G3260_RS14325	COG2124	cytochrome p450
G3260_RS14335	COG1482	cell wall glycoprotein biosynthetic process
G3260_RS14345	COG2835	tetraacyldisaccharide 4'-kinase activity
G3260_RS14350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3260_RS14385	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G3260_RS14390	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G3260_RS14390	COG0778	Nitroreductase
G3260_RS14420	COG1316	TRANSCRIPTIONal
G3260_RS14435	COG1316	TRANSCRIPTIONal
G3260_RS14440	COG1607	acyl-coa hydrolase
G3260_RS14445	COG1316	TRANSCRIPTIONal
G3260_RS14460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G3260_RS14515	COG0402	S-adenosylhomocysteine deaminase activity
G3260_RS14540	COG2205	protein histidine kinase activity
G3260_RS14545	COG0745	RESPONSE REGULATOR receiver
G3260_RS14550	COG3104	oligopeptide transport
G3260_RS14575	COG1366	Belongs to the anti-sigma-factor antagonist family
G3260_RS14580	COG1191	sigma factor activity
G3260_RS14590	COG0477	Major facilitator Superfamily
G3260_RS14595	COG1228	amidohydrolase
G3260_RS14610	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G3260_RS14620	COG0667	Aldo Keto reductase
G3260_RS14645	COG0673	inositol 2-dehydrogenase activity
G3260_RS14650	COG0395	ABC-type sugar transport system, permease component
G3260_RS14655	COG1175	transmembrane transport
G3260_RS14670	COG0110	maltose O-acetyltransferase activity
G3260_RS14685	COG2755	lipolytic protein G-D-S-L family
G3260_RS14690	COG0183	Belongs to the thiolase family
G3260_RS14735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3260_RS14740	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS14755	COG1136	(ABC) transporter
G3260_RS14760	COG0577	efflux transmembrane transporter activity
G3260_RS14765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3260_RS14800	COG0148	phosphopyruvate hydratase activity
G3260_RS14840	COG0515	serine threonine protein kinase
G3260_RS14850	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G3260_RS14875	COG1316	TRANSCRIPTIONal
G3260_RS14910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3260_RS14915	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G3260_RS14920	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G3260_RS14925	COG0193	aminoacyl-tRNA hydrolase activity
G3260_RS14930	COG2323	membrane
G3260_RS14945	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G3260_RS14955	COG1309	transcriptional regulator
G3260_RS14975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3260_RS14980	COG4106	trans-aconitate 2-methyltransferase activity
G3260_RS15000	COG2197	response regulator
G3260_RS15005	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G3260_RS15040	COG0488	(ABC) transporter
G3260_RS15050	COG0442	prolyl-tRNA aminoacylation
G3260_RS15080	COG0084	hydrolase, TatD family'
G3260_RS15085	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G3260_RS15090	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G3260_RS15125	COG2409	Drug exporters of the RND superfamily
G3260_RS15130	COG4946	Tricorn protease homolog
G3260_RS15130	COG0793	Belongs to the peptidase S41A family
G3260_RS15140	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS15145	COG2267	carboxylic ester hydrolase activity
G3260_RS15150	COG2072	flavoprotein involved in K transport
G3260_RS15180	COG3903	Transcriptional regulator
G3260_RS15180	COG3629	intracellular signal transduction
G3260_RS15185	COG0708	Exodeoxyribonuclease III
G3260_RS15195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G3260_RS15240	COG0154	amidase activity
G3260_RS15260	COG0521	Mo-molybdopterin cofactor biosynthetic process
G3260_RS15265	COG0315	cyclic pyranopterin monophosphate synthase activity
G3260_RS15275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G3260_RS15280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G3260_RS15290	COG3263	regulation of cellular component size
G3260_RS15305	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G3260_RS15315	COG1970	mechanosensitive ion channel activity
G3260_RS15325	COG3191	aminopeptidase activity
G3260_RS15340	COG1309	transcriptional regulator
G3260_RS15345	COG1472	Belongs to the glycosyl hydrolase 3 family
G3260_RS15355	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
G3260_RS15385	COG4585	Histidine kinase
G3260_RS15390	COG2197	response regulator
G3260_RS15400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3260_RS15405	COG0604	alcohol dehydrogenase
G3260_RS15410	COG0583	DNA-binding transcription factor activity
G3260_RS15420	COG1254	Belongs to the acylphosphatase family
G3260_RS15460	COG1686	Belongs to the peptidase S11 family
G3260_RS15495	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G3260_RS15590	COG1024	Enoyl-CoA hydratase
G3260_RS15625	COG1309	transcriptional regulator
G3260_RS15635	COG1960	acyl-CoA dehydrogenase activity
G3260_RS15640	COG0183	Belongs to the thiolase family
G3260_RS15655	COG2072	flavoprotein involved in K transport
G3260_RS15665	COG1024	Enoyl-CoA hydratase
G3260_RS15685	COG4977	sequence-specific DNA binding
G3260_RS15690	COG1309	transcriptional regulator
G3260_RS15705	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS15710	COG1960	acyl-CoA dehydrogenase activity
G3260_RS15715	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS15745	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS15790	COG2945	thiolester hydrolase activity
G3260_RS15790	COG0596	Alpha beta hydrolase
G3260_RS15800	COG4821	SIS domain
G3260_RS15810	COG0259	pyridoxamine-phosphate oxidase activity
G3260_RS15865	COG1024	Enoyl-CoA hydratase
G3260_RS15880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3260_RS15960	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G3260_RS15970	COG0247	lactate metabolic process
G3260_RS15970	COG0277	FAD linked oxidase domain protein
G3260_RS15980	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G3260_RS16020	COG0667	Aldo Keto reductase
G3260_RS16045	COG2252	PERMEase
G3260_RS16055	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G3260_RS16075	COG2814	Major facilitator Superfamily
G3260_RS16085	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G3260_RS16090	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
G3260_RS16095	COG1278	Cold shock
G3260_RS16110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3260_RS16115	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3260_RS16120	COG1120	ATPase activity
G3260_RS16125	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G3260_RS16165	COG1061	Type III restriction enzyme res subunit
G3260_RS16170	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS16180	COG3973	AAA domain
G3260_RS16185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3260_RS16195	COG1742	UPF0060 membrane protein
G3260_RS16200	COG3142	Participates in the control of copper homeostasis
G3260_RS16210	COG2814	Major facilitator Superfamily
G3260_RS16225	COG1737	Transcriptional regulator
G3260_RS16230	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G3260_RS16275	COG0459	protein refolding
G3260_RS16280	COG1278	Cold shock
G3260_RS16295	COG0463	Glycosyl transferase, family 2
G3260_RS16325	COG1959	2 iron, 2 sulfur cluster binding
G3260_RS16340	COG1105	Belongs to the carbohydrate kinase PfkB family
G3260_RS16360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G3260_RS16395	COG1278	Cold shock
G3260_RS16430	COG3842	ATPase activity
G3260_RS16440	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G3260_RS16455	COG0215	cysteine-tRNA ligase activity
G3260_RS16475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3260_RS16490	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G3260_RS16495	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G3260_RS16500	COG1329	Transcriptional regulator
G3260_RS16515	COG0745	RESPONSE REGULATOR receiver
G3260_RS16520	COG5002	protein histidine kinase activity
G3260_RS16535	COG0588	phosphoglycerate mutase activity
G3260_RS16555	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS16560	COG2211	Major facilitator Superfamily
G3260_RS16625	COG0438	transferase activity, transferring glycosyl groups
G3260_RS16640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G3260_RS16650	COG0456	acetyltransferase
G3260_RS16660	COG0745	RESPONSE REGULATOR receiver
G3260_RS16665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3260_RS16670	COG1609	Transcriptional regulator
G3260_RS16675	COG0745	RESPONSE REGULATOR receiver
G3260_RS16700	COG2897	thiosulfate sulfurtransferase activity
G3260_RS16715	COG3485	protocatechuate 3,4-dioxygenase
G3260_RS16725	COG0735	belongs to the Fur family
G3260_RS16730	COG0354	folic acid binding
G3260_RS16735	COG1490	D-aminoacyl-tRNA deacylase activity
G3260_RS16760	COG4257	antibiotic catabolic process
G3260_RS16765	COG0488	(ABC) transporter
G3260_RS16770	COG1309	transcriptional regulator
G3260_RS16780	COG2814	Major facilitator Superfamily
G3260_RS16790	COG1733	regulation of RNA biosynthetic process
G3260_RS16870	COG0306	phosphate transporter
G3260_RS16880	COG1937	Protein conserved in bacteria
G3260_RS16900	COG0671	phosphoesterase, PA-phosphatase related
G3260_RS16905	COG0741	lytic transglycosylase activity
G3260_RS16905	COG0739	heme binding
G3260_RS16905	COG1196	nuclear chromosome segregation
G3260_RS16965	COG1846	Transcriptional regulator
G3260_RS16980	COG1252	NADH dehydrogenase
G3260_RS17010	COG0579	oxidoreductase
G3260_RS17015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G3260_RS17075	COG0667	Aldo Keto reductase
G3260_RS17080	COG0739	heme binding
G3260_RS17080	COG0741	lytic transglycosylase activity
G3260_RS17080	COG1196	nuclear chromosome segregation
G3260_RS17110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3260_RS17140	COG0475	glutathione-regulated potassium exporter activity
G3260_RS17165	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G3260_RS17190	COG1063	alcohol dehydrogenase
G3260_RS17200	COG1191	sigma factor activity
G3260_RS17205	COG1191	sigma factor activity
G3260_RS17220	COG1846	Transcriptional regulator
G3260_RS17240	COG0745	RESPONSE REGULATOR receiver
G3260_RS17270	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS17275	COG1595	DNA-templated transcription, initiation
G3260_RS17295	COG1960	acyl-CoA dehydrogenase activity
G3260_RS17305	COG1960	acyl-CoA dehydrogenase activity
G3260_RS17315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3260_RS17340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3260_RS17355	COG0653	protein targeting
G3260_RS17375	COG0006	proline dipeptidase activity
G3260_RS17380	COG2770	Histidine kinase
G3260_RS17380	COG2208	phosphoserine phosphatase activity
G3260_RS17400	COG1999	signal sequence binding
G3260_RS17415	COG2837	iron assimilation
G3260_RS17425	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G3260_RS17430	COG0561	phosphatase activity
G3260_RS17435	COG1309	transcriptional regulator
G3260_RS17465	COG2378	regulation of single-species biofilm formation
G3260_RS17490	COG2807	transmembrane transport
G3260_RS17510	COG1131	(ABC) transporter
G3260_RS17525	COG0789	Transcriptional regulator
G3260_RS17545	COG1393	Belongs to the ArsC family
G3260_RS17560	COG0501	Belongs to the peptidase M48B family
G3260_RS17565	COG0561	phosphatase activity
G3260_RS17570	COG4988	ABC transporter
G3260_RS17575	COG1294	oxidase, subunit
G3260_RS17580	COG1271	oxidase subunit
G3260_RS17585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3260_RS17590	COG1609	Transcriptional regulator
G3260_RS17595	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G3260_RS17605	COG1695	Transcriptional regulator
G3260_RS17615	COG0626	cystathionine gamma-synthase activity
G3260_RS17620	COG3001	Fructosamine kinase
G3260_RS17625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3260_RS17630	COG1950	PFAM Membrane protein of
G3260_RS17635	COG0662	Cupin 2, conserved barrel domain protein
G3260_RS17650	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G3260_RS17680	COG2814	Major facilitator Superfamily
G3260_RS17685	COG1846	Transcriptional regulator
G3260_RS17715	COG0500	methyltransferase
G3260_RS17725	COG0242	peptide deformylase activity
G3260_RS17760	COG0359	binds to the 23S rRNA
G3260_RS17765	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G3260_RS17770	COG0629	single-stranded DNA binding
G3260_RS17775	COG0360	Binds together with S18 to 16S ribosomal RNA
G3260_RS17805	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G3260_RS17820	COG0617	tRNA 3'-terminal CCA addition
G3260_RS17835	COG0515	serine threonine protein kinase
G3260_RS17835	COG2815	serine threonine protein kinase
G3260_RS17840	COG1595	DNA-templated transcription, initiation
G3260_RS17855	COG3118	belongs to the thioredoxin family
G3260_RS17875	COG0357	Ribosomal RNA small subunit methyltransferase G
G3260_RS17885	COG0706	membrane insertase activity
G3260_RS17890	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G3260_RS17895	COG0594	ribonuclease P activity
G3260_RS17900	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G3260_RS17905	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G3260_RS17910	COG0592	DNA-directed DNA polymerase activity
G3260_RS17915	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G3260_RS17920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G3260_RS17925	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
G3260_RS17930	COG0187	DNA topoisomerase II activity
G3260_RS17935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G3260_RS17950	COG1295	ribonuclease BN
G3260_RS17960	COG0515	serine threonine protein kinase
G3260_RS17970	COG2188	Transcriptional regulator
G3260_RS17975	COG2814	Major facilitator Superfamily
G3260_RS17995	COG0705	Rhomboid family
G3260_RS18010	COG3764	Sortase (surface protein transpeptidase)
G3260_RS18025	COG3764	Sortase (surface protein transpeptidase)
G3260_RS18030	COG3764	Sortase (surface protein transpeptidase)
G3260_RS18035	COG0515	serine threonine protein kinase
G3260_RS18055	COG1716	ATPase activity
G3260_RS18060	COG1716	ATPase activity
G3260_RS18070	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3260_RS18075	COG1733	regulation of RNA biosynthetic process
G3260_RS18095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3260_RS18100	COG2151	metal-sulfur cluster biosynthetic enzyme
G3260_RS18105	COG3396	Phenylacetate-CoA oxygenase
G3260_RS18110	COG3460	Phenylacetate-CoA oxygenase
G3260_RS18145	COG3321	synthase
G3260_RS18145	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS18145	COG0604	alcohol dehydrogenase
G3260_RS18160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G3260_RS18170	COG0746	molybdenum cofactor guanylyltransferase activity
G3260_RS18175	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3260_RS18190	COG1522	sequence-specific DNA binding
G3260_RS18195	COG1309	transcriptional regulator
G3260_RS18205	COG0515	serine threonine protein kinase
G3260_RS18210	COG0515	serine threonine protein kinase
G3260_RS18230	COG0022	dehydrogenase e1 component
G3260_RS18235	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3260_RS18270	COG1362	aminopeptidase activity
G3260_RS18275	COG1960	acyl-CoA dehydrogenase activity
G3260_RS18290	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G3260_RS18310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3260_RS18325	COG1252	NADH dehydrogenase
G3260_RS18360	COG0598	Magnesium transport protein CorA
G3260_RS18370	COG1136	(ABC) transporter
G3260_RS18370	COG0577	efflux transmembrane transporter activity
G3260_RS18385	COG2197	response regulator
G3260_RS18395	COG3265	gluconokinase activity
G3260_RS18400	COG2186	Transcriptional regulator
G3260_RS18420	COG2080	2 iron, 2 sulfur cluster binding
G3260_RS18425	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G3260_RS18430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3260_RS18455	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G3260_RS18480	COG1801	Protein of unknown function DUF72
G3260_RS18530	COG2188	Transcriptional regulator
G3260_RS18540	COG0717	Belongs to the dCTP deaminase family
G3260_RS18570	COG2181	nitrate reductase activity
G3260_RS18570	COG0247	lactate metabolic process
G3260_RS18575	COG0443	Heat shock 70 kDa protein
G3260_RS18585	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G3260_RS18590	COG0484	heat shock protein binding
G3260_RS18595	COG0789	Transcriptional regulator
G3260_RS18605	COG0542	response to heat
G3260_RS18635	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G3260_RS18650	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G3260_RS18655	COG0191	fructose-bisphosphate aldolase activity
G3260_RS18665	COG3483	tryptophan 2,3-dioxygenase activity
G3260_RS18700	COG1674	ftsk spoiiie
G3260_RS18750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G3260_RS18765	COG1131	(ABC) transporter
G3260_RS18770	COG3559	Exporter of polyketide antibiotics
G3260_RS18780	COG0693	protein deglycase activity
G3260_RS18795	COG1522	sequence-specific DNA binding
G3260_RS18800	COG1280	lysine exporter protein (LysE YggA)
G3260_RS18810	COG0745	RESPONSE REGULATOR receiver
G3260_RS18820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3260_RS18825	COG1802	Transcriptional regulator
G3260_RS18840	COG0151	Belongs to the GarS family
G3260_RS18855	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G3260_RS18865	COG2197	response regulator
G3260_RS18880	COG1131	(ABC) transporter
G3260_RS18900	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G3260_RS18905	COG0047	phosphoribosylformylglycinamidine synthase activity
G3260_RS18910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G3260_RS18925	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G3260_RS18935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G3260_RS18960	COG1643	Atp-dependent helicase
G3260_RS18975	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G3260_RS18975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3260_RS18980	COG0785	Cytochrome C biogenesis protein
G3260_RS18990	COG2197	response regulator
G3260_RS18995	COG4585	Histidine kinase
G3260_RS19030	COG0513	Belongs to the DEAD box helicase family
G3260_RS19045	COG0494	nUDIX hydrolase
G3260_RS19060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G3260_RS19105	COG4585	Histidine kinase
G3260_RS19110	COG2197	response regulator
G3260_RS19125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3260_RS19145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3260_RS19150	COG0640	Transcriptional regulator
G3260_RS19175	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G3260_RS19180	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G3260_RS19190	COG2304	oxidoreductase activity
G3260_RS19230	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
G3260_RS19305	COG4191	Histidine kinase
G3260_RS19360	COG0017	Asparaginyl-tRNA synthetase
G3260_RS19365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3260_RS19375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3260_RS19380	COG2192	nodulation
G3260_RS19395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G3260_RS19405	COG0297	glycogen (starch) synthase activity
G3260_RS19500	COG1408	metallophosphoesterase
G3260_RS19505	COG1610	YqeY-like protein
G3260_RS19510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3260_RS19520	COG0003	Pfam Anion-transporting ATPase
G3260_RS19545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3260_RS19575	COG2267	carboxylic ester hydrolase activity
G3260_RS19585	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G3260_RS19590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3260_RS19650	COG1205	dead DEAH box helicase
G3260_RS19650	COG1111	helicase
G3260_RS19655	COG1366	Belongs to the anti-sigma-factor antagonist family
G3260_RS19665	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G3260_RS19675	COG2890	protein-(glutamine-N5) methyltransferase activity
G3260_RS19690	COG1754	DNA topoisomerase type I activity
G3260_RS19690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3260_RS19695	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G3260_RS19795	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3260_RS19810	COG2197	response regulator
G3260_RS19815	COG4585	Histidine kinase
G3260_RS19870	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G3260_RS19875	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G3260_RS19900	COG2197	response regulator
G3260_RS19945	COG2851	Citrate transporter
G3260_RS19950	COG3290	protein histidine kinase activity
G3260_RS19955	COG4565	transcriptional regulatory protein
G3260_RS20010	COG1595	DNA-templated transcription, initiation
G3260_RS20020	COG1846	Transcriptional regulator
G3260_RS20035	COG1077	Cell shape determining protein MreB Mrl
G3260_RS20040	COG1132	(ABC) transporter
G3260_RS20060	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS20065	COG2318	DinB family
G3260_RS20075	COG0789	Transcriptional regulator
G3260_RS20085	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G3260_RS20090	COG2027	D-alanyl-D-alanine carboxypeptidase
G3260_RS20100	COG0037	tRNA processing
G3260_RS20115	COG0302	gtp cyclohydrolase
G3260_RS20125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G3260_RS20130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G3260_RS20160	COG0649	NAD binding
G3260_RS20185	COG1125	glycine betaine transport
G3260_RS20185	COG0517	IMP dehydrogenase activity
G3260_RS20210	COG2197	response regulator
G3260_RS20215	COG0640	Transcriptional regulator
G3260_RS20230	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G3260_RS20235	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G3260_RS20240	COG0157	Belongs to the NadC ModD family
G3260_RS20245	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G3260_RS20265	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G3260_RS20295	COG0739	heme binding
G3260_RS20300	COG1309	transcriptional regulator
G3260_RS20305	COG0477	Major facilitator Superfamily
G3260_RS20310	COG1194	a g-specific adenine glycosylase
G3260_RS20320	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
G3260_RS20340	COG0248	Ppx GppA phosphatase
G3260_RS20345	COG1082	Xylose isomerase domain protein TIM barrel
G3260_RS20350	COG0129	dihydroxy-acid dehydratase activity
G3260_RS20370	COG2409	Drug exporters of the RND superfamily
G3260_RS20375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G3260_RS20385	COG4585	Histidine kinase
G3260_RS20405	COG0123	including yeast histone deacetylase and acetoin utilization protein
G3260_RS20450	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
G3260_RS20455	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G3260_RS20460	COG0181	hydroxymethylbilane synthase activity
G3260_RS20465	COG1648	precorrin-2 dehydrogenase activity
G3260_RS20465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G3260_RS20470	COG0113	porphobilinogen synthase activity
G3260_RS20475	COG0018	arginyl-trna synthetase
G3260_RS20480	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
G3260_RS20500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3260_RS20515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G3260_RS20520	COG0406	alpha-ribazole phosphatase activity
G3260_RS20525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3260_RS20535	COG1333	cytochrome c biogenesis protein
G3260_RS20540	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G3260_RS20555	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G3260_RS20575	COG0163	prenyltransferase activity
G3260_RS20585	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G3260_RS20590	COG1573	uracil-dna glycosylase
G3260_RS20600	COG1301	dicarboxylic acid transport
G3260_RS20630	COG2175	clavaminate synthase activity
G3260_RS20635	COG0824	Thioesterase
G3260_RS20635	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3260_RS20640	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3260_RS20645	COG3246	L-lysine catabolic process to acetate
G3260_RS20670	COG0601	transmembrane transport
G3260_RS20675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3260_RS20685	COG4608	Belongs to the ABC transporter superfamily
G3260_RS20700	COG2814	Major facilitator Superfamily
G3260_RS20710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3260_RS20720	COG1070	Carbohydrate kinase
G3260_RS20725	COG2376	Dihydroxyacetone kinase
G3260_RS20730	COG0698	ribose 5-phosphate isomerase
G3260_RS20740	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
G3260_RS20750	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G3260_RS20755	COG2226	methyltransferase
G3260_RS20790	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3260_RS20795	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3260_RS20800	COG0649	NAD binding
G3260_RS20810	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G3260_RS20815	COG1034	ATP synthesis coupled electron transport
G3260_RS20820	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G3260_RS20825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3260_RS20830	COG0839	Belongs to the complex I subunit 6 family
G3260_RS20835	COG0713	ATP synthesis coupled electron transport
G3260_RS20840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G3260_RS20850	COG1007	ATP synthesis coupled electron transport
G3260_RS20865	COG0514	ATP-dependent DNA helicase (RecQ)
G3260_RS20875	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3260_RS20885	COG3104	oligopeptide transport
G3260_RS20915	COG1013	pyruvate-flavodoxin oxidoreductase activity
G3260_RS20920	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G3260_RS20920	COG0674	pyruvate-flavodoxin oxidoreductase activity
G3260_RS20930	COG4585	Histidine kinase
G3260_RS20935	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3260_RS20940	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3260_RS20945	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3260_RS20950	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G3260_RS20960	COG0839	Belongs to the complex I subunit 6 family
G3260_RS20965	COG0713	ATP synthesis coupled electron transport
G3260_RS20970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G3260_RS20980	COG1007	ATP synthesis coupled electron transport
G3260_RS20985	COG0501	Belongs to the peptidase M48B family
G3260_RS20990	COG3304	Inner membrane component domain
G3260_RS20995	COG1666	GTP binding
G3260_RS21005	COG0702	epimerase
G3260_RS21025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G3260_RS21030	COG2030	dehydratase
G3260_RS21040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G3260_RS21045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3260_RS21050	COG0436	Aminotransferase
G3260_RS21070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G3260_RS21075	COG0081	regulation of translation
G3260_RS21085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G3260_RS21090	COG0222	ribosome binding
G3260_RS21095	COG0085	RNA polymerase activity
G3260_RS21100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G3260_RS21110	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G3260_RS21115	COG0049	tRNA binding
G3260_RS21120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G3260_RS21125	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3260_RS21135	COG3550	peptidyl-serine autophosphorylation
G3260_RS21140	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G3260_RS21220	COG0051	transcription antitermination factor activity, RNA binding
G3260_RS21225	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G3260_RS21230	COG0088	Forms part of the polypeptide exit tunnel
G3260_RS21235	COG0089	rRNA binding
G3260_RS21240	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G3260_RS21245	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G3260_RS21250	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G3260_RS21255	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G3260_RS21260	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G3260_RS21265	COG0255	Belongs to the universal ribosomal protein uL29 family
G3260_RS21270	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G3260_RS21275	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G3260_RS21280	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G3260_RS21285	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G3260_RS21290	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G3260_RS21300	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G3260_RS21305	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G3260_RS21310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G3260_RS21315	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G3260_RS21320	COG1841	ribosomal large subunit assembly
G3260_RS21325	COG0200	Binds to the 23S rRNA
G3260_RS21335	COG0563	adenylate kinase activity
G3260_RS21345	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G3260_RS21350	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G3260_RS21355	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G3260_RS21360	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G3260_RS21365	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G3260_RS21375	COG0203	ribosomal protein L17
G3260_RS21380	COG0101	tRNA pseudouridine synthase activity
G3260_RS21385	COG2268	Band 7 protein
G3260_RS21400	COG0488	(ABC) transporter
G3260_RS21405	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G3260_RS21410	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G3260_RS21415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3260_RS21420	COG1072	(Pantothenic acid kinase))
G3260_RS21430	COG0736	holo-[acyl-carrier-protein] synthase activity
G3260_RS21445	COG2318	DinB family
G3260_RS21450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G3260_RS21460	COG0802	atpase or kinase
G3260_RS21480	COG1214	PFAM Peptidase M22, glycoprotease
G3260_RS21480	COG0456	acetyltransferase
G3260_RS21490	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G3260_RS21520	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G3260_RS21530	COG4221	oxidoreductase activity
G3260_RS21540	COG0583	DNA-binding transcription factor activity
G3260_RS21550	COG2197	response regulator
G3260_RS21555	COG1595	DNA-templated transcription, initiation
G3260_RS21565	COG0516	GMP reductase activity
G3260_RS21575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G3260_RS21580	COG2815	serine threonine protein kinase
G3260_RS21580	COG0515	serine threonine protein kinase
G3260_RS21595	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS21605	COG1605	Chorismate mutase
G3260_RS21610	COG0519	Catalyzes the synthesis of GMP from XMP
G3260_RS21610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G3260_RS21640	COG1476	TRANSCRIPTIONal
G3260_RS21655	COG2197	response regulator
G3260_RS21710	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3260_RS21710	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3260_RS21725	COG0714	Associated with various cellular activities
G3260_RS21730	COG2425	protein containing a von Willebrand factor type A (vWA) domain
G3260_RS21735	COG3552	Protein containing von Willebrand factor type A (VWA) domain
G3260_RS21740	COG0045	succinate-CoA ligase (ADP-forming) activity
G3260_RS21770	COG0138	bifunctional purine biosynthesis protein purh
G3260_RS21785	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G3260_RS21800	COG0039	L-malate dehydrogenase activity
G3260_RS21820	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS21830	COG4175	Glycine betaine
G3260_RS21830	COG0517	IMP dehydrogenase activity
G3260_RS21835	COG4176	ABC-type proline glycine betaine transport system permease component
G3260_RS21855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3260_RS21860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3260_RS21895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3260_RS21900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3260_RS21905	COG0180	Tryptophanyl-tRNA synthetase
G3260_RS21930	COG1408	metallophosphoesterase
G3260_RS21990	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3260_RS22005	COG2009	succinate dehydrogenase
G3260_RS22015	COG3525	Glycosyl hydrolase, family 20, catalytic domain
G3260_RS22020	COG1595	DNA-templated transcription, initiation
G3260_RS22060	COG1216	Glycosyl transferase, family 2
G3260_RS22075	COG2089	acid synthase
G3260_RS22100	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G3260_RS22100	COG1473	amidohydrolase
G3260_RS22140	COG2826	transposase and inactivated derivatives, IS30 family
G3260_RS22145	COG2814	Major facilitator Superfamily
G3260_RS22150	COG0583	DNA-binding transcription factor activity
G3260_RS22160	COG0789	Transcriptional regulator
G3260_RS22180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3260_RS22205	COG2205	protein histidine kinase activity
G3260_RS22210	COG0745	RESPONSE REGULATOR receiver
G3260_RS22215	COG1595	DNA-templated transcription, initiation
G3260_RS22275	COG1733	regulation of RNA biosynthetic process
G3260_RS22280	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS22285	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS22290	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G3260_RS22315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3260_RS22345	COG4770	biotin carboxylase activity
G3260_RS22355	COG0424	maF-like protein
G3260_RS22370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3260_RS22380	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G3260_RS22385	COG1024	Enoyl-CoA hydratase
G3260_RS22395	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS22400	COG0596	Alpha beta hydrolase
G3260_RS22405	COG1309	transcriptional regulator
G3260_RS22410	COG2986	histidine ammonia-lyase
G3260_RS22430	COG0402	S-adenosylhomocysteine deaminase activity
G3260_RS22435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3260_RS22445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G3260_RS22455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3260_RS22490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3260_RS22505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3260_RS22540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3260_RS22550	COG1331	Highly conserved protein containing a thioredoxin domain
G3260_RS22560	COG0436	Aminotransferase
G3260_RS22570	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G3260_RS22580	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3260_RS22595	COG1414	Transcriptional regulator
G3260_RS22605	COG2610	gluconate transmembrane transporter activity
G3260_RS22620	COG3325	Belongs to the glycosyl hydrolase 18 family
G3260_RS22620	COG3469	chitinase activity
G3260_RS22645	COG2894	cell division
G3260_RS22685	COG2885	chlorophyll binding
G3260_RS22715	COG0667	Aldo Keto reductase
G3260_RS22720	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G3260_RS22725	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G3260_RS22750	COG1136	(ABC) transporter
G3260_RS22775	COG0450	alkyl hydroperoxide reductase
G3260_RS22780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3260_RS22790	COG2226	methyltransferase
G3260_RS22800	COG0114	fumarate hydratase activity
G3260_RS22815	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
G3260_RS22815	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
G3260_RS22840	COG0778	Nitroreductase
G3260_RS22845	COG1722	exodeoxyribonuclease VII activity
G3260_RS22850	COG1570	exodeoxyribonuclease VII activity
G3260_RS22860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G3260_RS22865	COG1309	transcriptional regulator
G3260_RS22880	COG0012	GTP binding
G3260_RS22925	COG2197	response regulator
G3260_RS22930	COG2197	response regulator
G3260_RS22935	COG4585	Histidine kinase
G3260_RS22980	COG0671	phosphoesterase, PA-phosphatase related
G3260_RS22985	COG2197	response regulator
G3260_RS23000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3260_RS23040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3260_RS23050	COG4608	Belongs to the ABC transporter superfamily
G3260_RS23060	COG0601	transmembrane transport
G3260_RS23065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3260_RS23075	COG4608	Belongs to the ABC transporter superfamily
G3260_RS23100	COG0444	Belongs to the ABC transporter superfamily
G3260_RS23105	COG4608	Belongs to the ABC transporter superfamily
G3260_RS23120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G3260_RS23135	COG1131	(ABC) transporter
G3260_RS23145	COG4585	Histidine kinase
G3260_RS23150	COG2197	response regulator
G3260_RS23185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3260_RS23190	COG1611	Belongs to the LOG family
G3260_RS23195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G3260_RS23205	COG0519	Catalyzes the synthesis of GMP from XMP
G3260_RS23210	COG1024	Enoyl-CoA hydratase
G3260_RS23225	COG1595	DNA-templated transcription, initiation
G3260_RS23235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3260_RS23240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3260_RS23260	COG2239	Acts as a magnesium transporter
G3260_RS23275	COG0598	Magnesium transport protein CorA
G3260_RS23285	COG2814	Major facilitator Superfamily
G3260_RS23295	COG0613	PHP domain protein
G3260_RS23300	COG2095	MarC family integral membrane protein
G3260_RS23305	COG0596	Alpha beta hydrolase
G3260_RS23375	COG0596	Alpha beta hydrolase
G3260_RS23395	COG0210	DNA helicase
G3260_RS23400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3260_RS23435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G3260_RS23485	COG1615	UPF0182 protein
G3260_RS23525	COG0753	catalase activity
G3260_RS23530	COG0483	inositol monophosphate 1-phosphatase activity
G3260_RS23540	COG2076	Multidrug Resistance protein
G3260_RS23545	COG1162	GTPase activity
G3260_RS23550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G3260_RS23560	COG2135	peptidase activity
G3260_RS23570	COG1595	DNA-templated transcription, initiation
G3260_RS23575	COG5662	AntiSigma factor
G3260_RS23595	COG0242	peptide deformylase activity
G3260_RS23600	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3260_RS23625	COG1966	Carbon starvation protein
G3260_RS23630	COG2188	Transcriptional regulator
G3260_RS23635	COG2182	Extracellular solute-binding protein
G3260_RS23640	COG1175	transmembrane transport
G3260_RS23645	COG0395	ABC-type sugar transport system, permease component
G3260_RS23650	COG1472	Belongs to the glycosyl hydrolase 3 family
G3260_RS23655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G3260_RS23660	COG0235	Class ii aldolase
G3260_RS23675	COG1597	lipid kinase activity
G3260_RS23725	COG5006	permease, DMT superfamily
G3260_RS23730	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G3260_RS23740	COG2154	pterin-4-alpha-carbinolamine dehydratase
G3260_RS23745	COG0242	peptide deformylase activity
G3260_RS23765	COG4106	trans-aconitate 2-methyltransferase activity
G3260_RS23770	COG0281	malic enzyme
G3260_RS23775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3260_RS23780	COG0765	amino acid transport
G3260_RS23795	COG0604	alcohol dehydrogenase
G3260_RS23800	COG2267	carboxylic ester hydrolase activity
G3260_RS23805	COG3971	2-oxopent-4-enoate hydratase activity
G3260_RS23810	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G3260_RS23815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3260_RS23820	COG1414	Transcriptional regulator
G3260_RS23850	COG2070	2-Nitropropane dioxygenase
G3260_RS23865	COG1024	Enoyl-CoA hydratase
G3260_RS23870	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS23875	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS23880	COG1960	acyl-CoA dehydrogenase activity
G3260_RS23890	COG3594	Acyltransferase
G3260_RS23895	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G3260_RS23910	COG0183	Belongs to the thiolase family
G3260_RS23915	COG1309	transcriptional regulator
G3260_RS23925	COG1960	acyl-CoA dehydrogenase activity
G3260_RS23930	COG1024	Enoyl-CoA hydratase
G3260_RS23935	COG1960	acyl-CoA dehydrogenase activity
G3260_RS23940	COG1960	acyl-CoA dehydrogenase activity
G3260_RS23975	COG1695	Transcriptional regulator
G3260_RS23985	COG2365	Tyrosine phosphatase family
G3260_RS24000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3260_RS24005	COG1959	2 iron, 2 sulfur cluster binding
G3260_RS24010	COG0477	Major facilitator Superfamily
G3260_RS24035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3260_RS24045	COG1960	acyl-CoA dehydrogenase activity
G3260_RS24065	COG4585	Histidine kinase
G3260_RS24100	COG2255	four-way junction helicase activity
G3260_RS24120	COG0567	Dehydrogenase, E1 component
G3260_RS24120	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3260_RS24125	COG2205	protein histidine kinase activity
G3260_RS24130	COG0745	RESPONSE REGULATOR receiver
G3260_RS24150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3260_RS24160	COG1846	Transcriptional regulator
G3260_RS24165	COG2018	Roadblock/LC7 domain
G3260_RS24180	COG0791	NLP P60 protein
G3260_RS24215	COG0443	Heat shock 70 kDa protein
G3260_RS24225	COG1309	transcriptional regulator
G3260_RS24365	COG0018	arginyl-trna synthetase
G3260_RS24365	COG0018	arginyl-trna synthetase
G3260_RS24370	COG0019	diaminopimelate decarboxylase activity
G3260_RS24380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G3260_RS24385	COG0083	homoserine kinase activity
G3260_RS24395	COG1316	TRANSCRIPTIONal
G3260_RS24400	COG0254	rRNA binding
G3260_RS24405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G3260_RS24410	COG2890	protein-(glutamine-N5) methyltransferase activity
G3260_RS24420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3260_RS24440	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G3260_RS24445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G3260_RS24450	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G3260_RS24455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G3260_RS24460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G3260_RS24465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G3260_RS24470	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G3260_RS24480	COG2197	response regulator
G3260_RS24505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3260_RS24530	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3260_RS24545	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
G3260_RS24580	COG1131	(ABC) transporter
G3260_RS24600	COG0183	Belongs to the thiolase family
G3260_RS24615	COG0745	RESPONSE REGULATOR receiver
G3260_RS24620	COG2205	protein histidine kinase activity
G3260_RS24675	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3260_RS24675	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3260_RS24710	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G3260_RS24715	COG0280	phosphate acetyltransferase
G3260_RS24715	COG0857	belongs to the CobB CobQ family
G3260_RS24720	COG0205	6-phosphofructokinase activity
G3260_RS24725	COG2815	serine threonine protein kinase
G3260_RS24725	COG0515	serine threonine protein kinase
G3260_RS24730	COG0395	ABC-type sugar transport system, permease component
G3260_RS24740	COG1175	transmembrane transport
G3260_RS24750	COG4565	transcriptional regulatory protein
G3260_RS24755	COG3290	protein histidine kinase activity
G3260_RS24760	COG1301	dicarboxylic acid transport
G3260_RS24765	COG0366	Alpha amylase catalytic
G3260_RS24820	COG0783	Belongs to the Dps family
G3260_RS24840	COG1760	l-serine dehydratase
G3260_RS24845	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3260_RS24850	COG0509	glycine decarboxylation via glycine cleavage system
G3260_RS24855	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G3260_RS24880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3260_RS24885	COG4166	transmembrane transport
G3260_RS24900	COG4608	Belongs to the ABC transporter superfamily
G3260_RS24905	COG2860	membrane
G3260_RS24935	COG0482	sulfurtransferase activity
G3260_RS24940	COG1611	Belongs to the LOG family
G3260_RS24950	COG1077	Cell shape determining protein MreB Mrl
G3260_RS24955	COG4221	oxidoreductase activity
G3260_RS24965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G3260_RS24975	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G3260_RS24980	COG0154	amidase activity
G3260_RS24990	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G3260_RS25055	COG2409	Drug exporters of the RND superfamily
G3260_RS25065	COG2197	response regulator
G3260_RS25075	COG2133	pyrroloquinoline quinone binding
G3260_RS25080	COG0667	Aldo Keto reductase
G3260_RS25100	COG0440	acetolactate synthase activity
G3260_RS25105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G3260_RS25110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3260_RS25115	COG3835	regulator
G3260_RS25120	COG0506	proline dehydrogenase activity
G3260_RS25125	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS25130	COG0473	3-isopropylmalate dehydrogenase activity
G3260_RS25135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3260_RS25140	COG3540	Alkaline phosphatase
G3260_RS25150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3260_RS25160	COG2957	Belongs to the agmatine deiminase family
G3260_RS25165	COG0804	urea catabolic process
G3260_RS25170	COG0831	urea catabolic process
G3260_RS25170	COG0832	Belongs to the urease beta subunit family
G3260_RS25180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3260_RS25200	COG2018	Roadblock/LC7 domain
G3260_RS25220	COG2018	Roadblock/LC7 domain
G3260_RS25235	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3260_RS25240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3260_RS25270	COG1414	Transcriptional regulator
G3260_RS25275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3260_RS25280	COG0066	3-isopropylmalate dehydratase activity
G3260_RS25290	COG0776	regulation of translation
G3260_RS25300	COG1920	GTP binding
G3260_RS25310	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G3260_RS25315	COG1181	Belongs to the D-alanine--D-alanine ligase family
G3260_RS25335	COG0351	phosphomethylpyrimidine kinase
G3260_RS25340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G3260_RS25345	COG1461	Dihydroxyacetone kinase
G3260_RS25350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G3260_RS25355	COG0742	ribosomal rna small subunit methyltransferase
G3260_RS25375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G3260_RS25380	COG0571	ribonuclease III activity
G3260_RS25385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G3260_RS25395	COG1254	Belongs to the acylphosphatase family
G3260_RS25405	COG1196	nuclear chromosome segregation
G3260_RS25410	COG0477	Major facilitator Superfamily
G3260_RS25445	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G3260_RS25465	COG0228	four-way junction DNA binding
G3260_RS25470	COG1837	Belongs to the UPF0109 family
G3260_RS25475	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G3260_RS25480	COG0336	Belongs to the RNA methyltransferase TrmD family
G3260_RS25485	COG0335	large ribosomal subunit rRNA binding
G3260_RS25490	COG0681	Belongs to the peptidase S26 family
G3260_RS25500	COG0681	Belongs to the peptidase S26 family
G3260_RS25515	COG0792	nuclease activity
G3260_RS25530	COG1191	sigma factor activity
G3260_RS25545	COG0052	Belongs to the universal ribosomal protein uS2 family
G3260_RS25550	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G3260_RS25555	COG0528	UMP kinase activity
G3260_RS25560	COG0233	cytoplasmic translational termination
G3260_RS25570	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G3260_RS25585	COG3842	ATPase activity
G3260_RS25595	COG1136	(ABC) transporter
G3260_RS25600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3260_RS25610	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS25625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3260_RS25635	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS25645	COG3842	ATPase activity
G3260_RS25650	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3260_RS25660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3260_RS25680	COG2508	Transcriptional regulator
G3260_RS25685	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS25710	COG4585	Histidine kinase
G3260_RS25715	COG2197	response regulator
G3260_RS25725	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G3260_RS25730	COG0750	zinc metalloprotease
G3260_RS25735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G3260_RS25750	COG0442	prolyl-tRNA aminoacylation
G3260_RS25755	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
G3260_RS25770	COG0779	Required for maturation of 30S ribosomal subunits
G3260_RS25785	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G3260_RS25795	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G3260_RS25800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G3260_RS25815	COG0455	bacterial-type flagellum organization
G3260_RS25830	COG3266	domain, Protein
G3260_RS25870	COG1674	ftsk spoiiie
G3260_RS25880	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G3260_RS25885	COG1185	polyribonucleotide nucleotidyltransferase activity
G3260_RS25890	COG0612	Peptidase, M16
G3260_RS25895	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G3260_RS25915	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
G3260_RS25920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3260_RS25925	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G3260_RS25955	COG2208	phosphoserine phosphatase activity
G3260_RS25955	COG2770	Histidine kinase
G3260_RS25960	COG3850	Histidine kinase
G3260_RS25960	COG3437	response regulator, receiver
G3260_RS25960	COG3437	response regulator, receiver
G3260_RS25960	COG3850	Histidine kinase
G3260_RS25960	COG4999	Histidine kinase
G3260_RS25960	COG2205	protein histidine kinase activity
G3260_RS25960	COG4999	Histidine kinase
G3260_RS25960	COG2205	protein histidine kinase activity
G3260_RS25970	COG1674	ftsk spoiiie
G3260_RS25980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G3260_RS25990	COG1058	Belongs to the CinA family
G3260_RS25990	COG1546	Belongs to the CinA family
G3260_RS25995	COG1396	sequence-specific DNA binding
G3260_RS26000	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS26005	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G3260_RS26050	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G3260_RS26060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3260_RS26065	COG0765	amino acid transport
G3260_RS26070	COG0765	amino acid transport
G3260_RS26075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3260_RS26080	COG1126	abc transporter atp-binding protein
G3260_RS26085	COG0745	RESPONSE REGULATOR receiver
G3260_RS26090	COG2205	protein histidine kinase activity
G3260_RS26105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G3260_RS26125	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G3260_RS26135	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G3260_RS26140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3260_RS26150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G3260_RS26185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G3260_RS26195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3260_RS26205	COG0588	phosphoglycerate mutase activity
G3260_RS26215	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G3260_RS26245	COG1131	(ABC) transporter
G3260_RS26250	COG1802	Transcriptional regulator
G3260_RS26255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G3260_RS26270	COG0187	DNA topoisomerase II activity
G3260_RS26280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3260_RS26285	COG3290	protein histidine kinase activity
G3260_RS26300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G3260_RS26305	COG0612	Peptidase, M16
G3260_RS26320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3260_RS26325	COG1042	CoA-binding domain protein
G3260_RS26325	COG0045	succinate-CoA ligase (ADP-forming) activity
G3260_RS26325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3260_RS26340	COG1435	thymidine kinase activity
G3260_RS26390	COG0745	RESPONSE REGULATOR receiver
G3260_RS26395	COG2205	protein histidine kinase activity
G3260_RS26420	COG0756	dUTP diphosphatase activity
G3260_RS26435	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
G3260_RS26440	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G3260_RS26445	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G3260_RS26450	COG1136	(ABC) transporter
G3260_RS26450	COG4591	ABC-type transport system involved in lipoprotein release permease component
G3260_RS26475	COG1470	cell adhesion involved in biofilm formation
G3260_RS26485	COG0569	domain protein
G3260_RS26490	COG0531	amino acid
G3260_RS26495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G3260_RS26505	COG1518	maintenance of DNA repeat elements
G3260_RS26510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G3260_RS26550	COG3654	unkown
G3260_RS26570	COG2367	Beta-lactamase
G3260_RS26590	COG1404	Belongs to the peptidase S8 family
G3260_RS26595	COG1674	ftsk spoiiie
G3260_RS26605	COG3266	domain, Protein
G3260_RS26685	COG0442	prolyl-tRNA aminoacylation
G3260_RS26695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3260_RS26705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3260_RS26735	COG0477	Major facilitator Superfamily
G3260_RS26765	COG2267	carboxylic ester hydrolase activity
G3260_RS26790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3260_RS26795	COG2226	methyltransferase
G3260_RS26835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3260_RS26885	COG0019	diaminopimelate decarboxylase activity
G3260_RS26900	COG2188	Transcriptional regulator
G3260_RS26920	COG1735	metal-dependent hydrolase with the TIM-barrel fold
G3260_RS26925	COG0626	cystathionine gamma-synthase activity
G3260_RS26930	COG3457	Alanine racemase
G3260_RS26935	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G3260_RS26950	COG2197	response regulator
G3260_RS26955	COG0656	L-ascorbic acid biosynthetic process
G3260_RS27015	COG0531	amino acid
G3260_RS27020	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G3260_RS27030	COG2040	homocysteine
G3260_RS27080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3260_RS27090	COG2814	Major facilitator Superfamily
G3260_RS27095	COG0673	inositol 2-dehydrogenase activity
G3260_RS27105	COG3842	ATPase activity
G3260_RS27110	COG1725	Transcriptional regulator
G3260_RS27180	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS27185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3260_RS27225	COG1203	CRISPR-associated helicase, Cas3
G3260_RS27235	COG1518	maintenance of DNA repeat elements
G3260_RS27240	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
G3260_RS27245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G3260_RS27255	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G3260_RS27260	COG1802	Transcriptional regulator
G3260_RS27275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3260_RS27305	COG1653	transport
G3260_RS27310	COG1175	transmembrane transport
G3260_RS27315	COG0395	ABC-type sugar transport system, permease component
G3260_RS27330	COG0395	ABC-type sugar transport system, permease component
G3260_RS27335	COG1940	carbohydrate kinase activity
G3260_RS27340	COG4213	ABC transporter substrate-binding protein
G3260_RS27350	COG4214	carbohydrate transport
G3260_RS27365	COG1140	nitrate reductase beta subunit
G3260_RS27370	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
G3260_RS27380	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G3260_RS27390	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3260_RS27390	COG1024	Enoyl-CoA hydratase
G3260_RS27395	COG0183	Belongs to the thiolase family
G3260_RS27415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G3260_RS27420	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3260_RS27500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G3260_RS27505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3260_RS27510	COG0477	Major facilitator Superfamily
G3260_RS27530	COG1595	DNA-templated transcription, initiation
G3260_RS27535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3260_RS27540	COG0583	DNA-binding transcription factor activity
G3260_RS27545	COG0640	Transcriptional regulator
G3260_RS27550	COG0346	lactoylglutathione lyase activity
G3260_RS27570	COG1802	Transcriptional regulator
G3260_RS27575	COG0477	Major facilitator Superfamily
G3260_RS27580	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3260_RS27585	COG4948	Mandelate Racemase Muconate Lactonizing
G3260_RS27590	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS27595	COG2364	Membrane
G3260_RS27605	COG0583	DNA-binding transcription factor activity
G3260_RS27615	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS27655	COG0431	NADPH-dependent FMN reductase
G3260_RS27660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3260_RS27670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3260_RS27700	COG0529	Catalyzes the synthesis of activated sulfate
G3260_RS27705	COG0175	sulfate reduction
G3260_RS27715	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3260_RS27750	COG1254	Belongs to the acylphosphatase family
G3260_RS27760	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS27765	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS27780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3260_RS27785	COG0494	nUDIX hydrolase
G3260_RS27790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3260_RS27800	COG1960	acyl-CoA dehydrogenase activity
G3260_RS27810	COG1162	GTPase activity
G3260_RS27840	COG1802	Transcriptional regulator
G3260_RS27855	COG4585	Histidine kinase
G3260_RS27865	COG3835	regulator
G3260_RS27880	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3260_RS27885	COG2252	PERMEase
G3260_RS27900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3260_RS27910	COG0753	catalase activity
G3260_RS27915	COG3960	tartronate-semialdehyde synthase activity
G3260_RS27920	COG2084	Dehydrogenase
G3260_RS27925	COG3622	Belongs to the hyi family
G3260_RS27950	COG2351	hydroxyisourate hydrolase activity
G3260_RS27965	COG2233	PERMEase
G3260_RS27980	COG1733	regulation of RNA biosynthetic process
G3260_RS27985	COG3340	Belongs to the peptidase S51 family
G3260_RS28020	COG1288	antiporter activity
G3260_RS28035	COG0746	molybdenum cofactor guanylyltransferase activity
G3260_RS28045	COG1414	Transcriptional regulator
G3260_RS28050	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G3260_RS28055	COG4266	Belongs to the allantoicase family
G3260_RS28065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3260_RS28070	COG0800	Aldolase
G3260_RS28090	COG2188	Transcriptional regulator
G3260_RS28110	COG1940	carbohydrate kinase activity
G3260_RS28120	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3260_RS28125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G3260_RS28145	COG1126	abc transporter atp-binding protein
G3260_RS28150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3260_RS28155	COG0765	amino acid transport
G3260_RS28160	COG0765	amino acid transport
G3260_RS28165	COG0405	Gamma-glutamyltransferase
G3260_RS28175	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G3260_RS28180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3260_RS28185	COG1335	isochorismatase
G3260_RS28190	COG0477	Major facilitator Superfamily
G3260_RS28220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3260_RS28225	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G3260_RS28265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G3260_RS28270	COG0483	inositol monophosphate 1-phosphatase activity
G3260_RS28280	COG1929	Belongs to the glycerate kinase type-1 family
G3260_RS28285	COG2826	transposase and inactivated derivatives, IS30 family
G3260_RS28295	COG0688	phosphatidylethanolamine metabolic process
G3260_RS28300	COG1960	acyl-CoA dehydrogenase activity
G3260_RS28310	COG2301	Belongs to the HpcH HpaI aldolase family
G3260_RS28325	COG0531	amino acid
G3260_RS28375	COG2362	D-Aminopeptidase
G3260_RS28385	COG1506	peptidase
G3260_RS28385	COG0823	Involved in the tonB-independent uptake of proteins
G3260_RS28385	COG4946	Tricorn protease homolog
G3260_RS28390	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
G3260_RS28435	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G3260_RS28455	COG1959	2 iron, 2 sulfur cluster binding
G3260_RS28460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3260_RS28460	COG1017	nitric oxide dioxygenase activity
G3260_RS28470	COG2154	pterin-4-alpha-carbinolamine dehydratase
G3260_RS28475	COG0656	L-ascorbic acid biosynthetic process
G3260_RS28515	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G3260_RS28520	COG1940	carbohydrate kinase activity
G3260_RS28525	COG1129	ABC transporter
G3260_RS28530	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3260_RS28535	COG4213	ABC transporter substrate-binding protein
G3260_RS28540	COG0673	inositol 2-dehydrogenase activity
G3260_RS28615	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS28625	COG2072	flavoprotein involved in K transport
G3260_RS28645	COG0702	epimerase
G3260_RS28650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3260_RS28665	COG0640	Transcriptional regulator
G3260_RS28675	COG0477	Major facilitator Superfamily
G3260_RS28685	COG3511	phospholipase C
G3260_RS28705	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS28720	COG1132	(ABC) transporter
G3260_RS28745	COG2226	methyltransferase
G3260_RS28755	COG1309	transcriptional regulator
G3260_RS28770	COG2124	cytochrome p450
G3260_RS28785	COG0028	Belongs to the TPP enzyme family
G3260_RS28790	COG4948	Mandelate Racemase Muconate Lactonizing
G3260_RS28795	COG0247	lactate metabolic process
G3260_RS28795	COG0277	FAD linked oxidase domain protein
G3260_RS28800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3260_RS28830	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS28835	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS28845	COG2890	protein-(glutamine-N5) methyltransferase activity
G3260_RS28855	COG1295	ribonuclease BN
G3260_RS28875	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3260_RS28875	COG0515	serine threonine protein kinase
G3260_RS28890	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS28895	COG0583	DNA-binding transcription factor activity
G3260_RS28900	COG1674	ftsk spoiiie
G3260_RS28915	COG0515	serine threonine protein kinase
G3260_RS28915	COG2815	serine threonine protein kinase
G3260_RS28930	COG0714	Associated with various cellular activities
G3260_RS28940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3260_RS28945	COG1126	abc transporter atp-binding protein
G3260_RS28970	COG1140	nitrate reductase beta subunit
G3260_RS28990	COG1295	ribonuclease BN
G3260_RS29045	COG0437	4 iron, 4 sulfur cluster binding
G3260_RS29050	COG0243	molybdopterin cofactor binding
G3260_RS29050	COG3383	formate dehydrogenase (NAD+) activity
G3260_RS29055	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G3260_RS29085	COG2610	gluconate transmembrane transporter activity
G3260_RS29105	COG1515	deoxyribonuclease V activity
G3260_RS29120	COG0789	Transcriptional regulator
G3260_RS29160	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G3260_RS29165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3260_RS29220	COG1278	Cold shock
G3260_RS29225	COG2814	Major facilitator Superfamily
G3260_RS29240	COG1620	l-lactate permease
G3260_RS29245	COG3012	SEC-C Motif Domain Protein
G3260_RS29250	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS29265	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3260_RS29265	COG1902	pentaerythritol trinitrate reductase activity
G3260_RS29270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3260_RS29275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G3260_RS29285	COG3409	Peptidoglycan-binding domain 1 protein
G3260_RS29285	COG3757	hydrolase, family 25
G3260_RS29295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3260_RS29305	COG1349	DNA-binding transcription factor activity
G3260_RS29310	COG0191	fructose-bisphosphate aldolase activity
G3260_RS29315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G3260_RS29325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3260_RS29330	COG1960	acyl-CoA dehydrogenase activity
G3260_RS29335	COG0183	Belongs to the thiolase family
G3260_RS29340	COG1024	Enoyl-CoA hydratase
G3260_RS29340	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3260_RS29355	COG1113	amino acid transport
G3260_RS29410	COG0596	Alpha beta hydrolase
G3260_RS29440	COG0395	ABC-type sugar transport system, permease component
G3260_RS29445	COG0488	(ABC) transporter
G3260_RS29455	COG2183	response to ionizing radiation
G3260_RS29475	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
G3260_RS29490	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G3260_RS29515	COG1134	teichoic acid transport
G3260_RS29515	COG1388	LysM domain
G3260_RS29525	COG1562	ergosterol biosynthetic process
G3260_RS29535	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
G3260_RS29545	COG1657	PFAM Prenyltransferase squalene oxidase
G3260_RS29565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G3260_RS29570	COG4948	Mandelate Racemase Muconate Lactonizing
G3260_RS29595	COG2267	carboxylic ester hydrolase activity
G3260_RS29600	COG5001	Diguanylate cyclase
G3260_RS29620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3260_RS29630	COG1124	(ABC) transporter
G3260_RS29645	COG0723	plastoquinol--plastocyanin reductase activity
G3260_RS29645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3260_RS29650	COG1960	acyl-CoA dehydrogenase activity
G3260_RS29705	COG3973	AAA domain
G3260_RS29705	COG3973	AAA domain
G3260_RS29725	COG0589	response to stress
G3260_RS29730	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G3260_RS29735	COG0656	L-ascorbic acid biosynthetic process
G3260_RS29740	COG0537	adenosine 5'-monophosphoramidase activity
G3260_RS29745	COG1793	dna ligase
G3260_RS29750	COG1793	dna ligase
G3260_RS29770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3260_RS29770	COG2022	thiamine diphosphate biosynthetic process
G3260_RS29780	COG1309	transcriptional regulator
G3260_RS29820	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G3260_RS29830	COG0254	rRNA binding
G3260_RS29835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G3260_RS29840	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G3260_RS29845	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G3260_RS29865	COG0789	Transcriptional regulator
G3260_RS29870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G3260_RS29870	COG1024	Enoyl-CoA hydratase
G3260_RS29880	COG1609	Transcriptional regulator
G3260_RS29890	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS29940	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3260_RS29980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G3260_RS30055	COG0254	rRNA binding
G3260_RS30065	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS30075	COG1486	melibiose metabolic process
G3260_RS30085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3260_RS30095	COG1175	transmembrane transport
G3260_RS30115	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3260_RS30150	COG1902	pentaerythritol trinitrate reductase activity
G3260_RS30155	COG0789	Transcriptional regulator
G3260_RS30165	COG4638	Rieske (2fe-2S)
G3260_RS30170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3260_RS30185	COG1414	Transcriptional regulator
G3260_RS30190	COG2146	nitrite reductase [NAD(P)H] activity
G3260_RS30230	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS30275	COG0277	FAD linked oxidase domain protein
G3260_RS30280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G3260_RS30285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3260_RS30295	COG0110	maltose O-acetyltransferase activity
G3260_RS30300	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS30320	COG0492	ferredoxin-NADP+ reductase activity
G3260_RS30340	COG0438	transferase activity, transferring glycosyl groups
G3260_RS30350	COG0728	peptidoglycan biosynthetic process
G3260_RS30360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3260_RS30365	COG0438	transferase activity, transferring glycosyl groups
G3260_RS30400	COG2197	response regulator
G3260_RS30445	COG1063	alcohol dehydrogenase
G3260_RS30465	COG1349	DNA-binding transcription factor activity
G3260_RS30470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3260_RS30475	COG0477	Major facilitator Superfamily
G3260_RS30480	COG2188	Transcriptional regulator
G3260_RS30530	COG0435	Glutathione S-transferase
G3260_RS30550	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS30565	COG0517	IMP dehydrogenase activity
G3260_RS30570	COG3387	PFAM Glycoside hydrolase 15-related
G3260_RS30575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G3260_RS30590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G3260_RS30620	COG1982	Orn Lys Arg decarboxylase major
G3260_RS30625	COG0546	phosphoglycolate phosphatase activity
G3260_RS30655	COG2111	Na H antiporter
G3260_RS30660	COG1006	Multisubunit Na H antiporter MnhC subunit
G3260_RS30675	COG2197	response regulator
G3260_RS30680	COG1132	(ABC) transporter
G3260_RS30685	COG1132	(ABC) transporter
G3260_RS30695	COG0515	serine threonine protein kinase
G3260_RS30700	COG1024	Enoyl-CoA hydratase
G3260_RS30710	COG0301	tRNA thio-modification
G3260_RS30730	COG1063	alcohol dehydrogenase
G3260_RS30765	COG1278	Cold shock
G3260_RS30785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G3260_RS30785	COG0519	Catalyzes the synthesis of GMP from XMP
G3260_RS30805	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3260_RS30830	COG4221	oxidoreductase activity
G3260_RS30925	COG4336	lyase activity
G3260_RS30930	COG1960	acyl-CoA dehydrogenase activity
G3260_RS30940	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3260_RS30945	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G3260_RS30945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G3260_RS30950	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G3260_RS30955	COG0585	pseudouridine synthase activity
G3260_RS30960	COG1181	Belongs to the D-alanine--D-alanine ligase family
G3260_RS30985	COG1174	glycine betaine transport
G3260_RS30990	COG1174	glycine betaine transport
G3260_RS31000	COG1732	Glycine betaine
G3260_RS31005	COG2936	dipeptidyl-peptidase activity
G3260_RS31010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3260_RS31020	COG0494	nUDIX hydrolase
G3260_RS31045	COG1653	transport
G3260_RS31050	COG0395	ABC-type sugar transport system, permease component
G3260_RS31055	COG1175	transmembrane transport
G3260_RS31085	COG0583	DNA-binding transcription factor activity
G3260_RS31120	COG0604	alcohol dehydrogenase
G3260_RS31120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3260_RS31120	COG4221	oxidoreductase activity
G3260_RS31120	COG3321	synthase
G3260_RS31125	COG1733	regulation of RNA biosynthetic process
G3260_RS31155	COG1120	ATPase activity
G3260_RS31175	COG2197	response regulator
G3260_RS31180	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G3260_RS31200	COG1917	Cupin 2, conserved barrel domain protein
G3260_RS31200	COG4977	sequence-specific DNA binding
G3260_RS31250	COG0604	alcohol dehydrogenase
G3260_RS31295	COG2226	methyltransferase
G3260_RS31300	COG0456	acetyltransferase
G3260_RS31305	COG0640	Transcriptional regulator
G3260_RS31310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3260_RS31320	COG0477	Major facilitator Superfamily
G3260_RS31325	COG1012	belongs to the aldehyde dehydrogenase family
G3260_RS31340	COG2267	carboxylic ester hydrolase activity
G3260_RS31350	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS31380	COG1846	Transcriptional regulator
G3260_RS31385	COG2755	lipolytic protein G-D-S-L family
G3260_RS31385	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G3260_RS31395	COG0745	RESPONSE REGULATOR receiver
G3260_RS31400	COG2205	protein histidine kinase activity
G3260_RS31410	COG0583	DNA-binding transcription factor activity
G3260_RS31425	COG0590	tRNA wobble adenosine to inosine editing
G3260_RS31445	COG3795	YCII-related domain
G3260_RS31450	COG4941	Belongs to the sigma-70 factor family
G3260_RS31460	COG2814	Major facilitator Superfamily
G3260_RS31470	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G3260_RS31475	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
G3260_RS31485	COG1216	Glycosyl transferase, family 2
G3260_RS31495	COG4310	Domain of unknown function (DUF2172)
G3260_RS31510	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G3260_RS31520	COG0438	transferase activity, transferring glycosyl groups
G3260_RS31545	COG0367	asparagine synthase
G3260_RS31565	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G3260_RS31570	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3260_RS31605	COG1802	Transcriptional regulator
G3260_RS31615	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3260_RS31635	COG0583	DNA-binding transcription factor activity
G3260_RS31650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3260_RS31670	COG1309	transcriptional regulator
G3260_RS31705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3260_RS31710	COG3547	Transposase (IS116 IS110 IS902 family)
G3260_RS31725	COG0154	amidase activity
G3260_RS31780	COG2197	response regulator
G3260_RS31785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3260_RS31790	COG0318	PFAM AMP-dependent synthetase and ligase
G3260_RS31835	COG0765	amino acid transport
G3260_RS31840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3260_RS31880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G3260_RS31905	COG2018	Roadblock/LC7 domain
G3260_RS31915	COG1946	Acyl-CoA thioesterase
G3260_RS31935	COG1132	(ABC) transporter
G3260_RS31960	COG1132	(ABC) transporter
G3260_RS31990	COG3876	Protein conserved in bacteria
G3260_RS31995	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
G3260_RS32005	COG1119	ATPase activity
G3260_RS32015	COG1556	Lactate utilization protein
G3260_RS32020	COG1139	Iron-sulfur cluster binding protein
G3260_RS32025	COG0247	lactate metabolic process
G3260_RS32030	COG2072	flavoprotein involved in K transport
G3260_RS32035	COG0432	Pfam Uncharacterised protein family UPF0047
G3260_RS32080	COG0726	polysaccharide deacetylase
G3260_RS32095	COG0477	Major facilitator Superfamily
G3260_RS32160	COG2226	methyltransferase
G3260_RS32165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3260_RS32185	COG2971	BadF BadG BcrA BcrD
G3260_RS32190	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G3260_RS32215	COG1309	transcriptional regulator
G3260_RS32225	COG0671	phosphoesterase, PA-phosphatase related
G3260_RS32275	COG1486	melibiose metabolic process
G3260_RS32280	COG0395	ABC-type sugar transport system, permease component
G3260_RS32285	COG1175	transmembrane transport
G3260_RS32295	COG1940	carbohydrate kinase activity
G3260_RS32295	COG1846	Transcriptional regulator
G3260_RS32330	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G3260_RS32335	COG0121	glutamine amidotransferase
G3260_RS32340	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3260_RS32365	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
G3260_RS32370	COG1940	carbohydrate kinase activity
G3260_RS32375	COG2188	Transcriptional regulator
G3260_RS32380	COG2814	Major facilitator Superfamily
G3260_RS32390	COG2271	Major facilitator Superfamily
G3260_RS32405	COG0655	NAD(P)H dehydrogenase (quinone) activity
G3260_RS32415	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G3260_RS32430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3260_RS32445	COG0395	ABC-type sugar transport system, permease component
G3260_RS32465	COG4585	Histidine kinase
G3260_RS32480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G3260_RS32535	COG0604	alcohol dehydrogenase
G3260_RS32550	COG0477	Major facilitator Superfamily
G3260_RS32585	COG2267	carboxylic ester hydrolase activity
G3260_RS32595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G3260_RS32600	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G3260_RS32605	COG2814	Major facilitator Superfamily
G3260_RS32620	COG2197	response regulator
G3260_RS32635	COG0666	response to abiotic stimulus
G3260_RS32665	COG4585	Histidine kinase
G3260_RS32670	COG0577	efflux transmembrane transporter activity
G3260_RS32675	COG0577	efflux transmembrane transporter activity
G3260_RS32675	COG1136	(ABC) transporter
G3260_RS32680	COG2208	phosphoserine phosphatase activity
G3260_RS32680	COG2770	Histidine kinase
G3260_RS32735	COG2208	phosphoserine phosphatase activity
G3260_RS32735	COG2770	Histidine kinase
G3260_RS32750	COG1366	Belongs to the anti-sigma-factor antagonist family
G3260_RS32755	COG1366	Belongs to the anti-sigma-factor antagonist family
G3260_RS32780	COG1953	Uracil, thiamine, allantoin
G3260_RS32810	COG0402	S-adenosylhomocysteine deaminase activity
G3260_RS32830	COG2124	cytochrome p450
G3260_RS32860	COG1657	PFAM Prenyltransferase squalene oxidase
G3260_RS32865	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
G3260_RS32870	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS32915	COG1309	transcriptional regulator
G3260_RS32960	COG0395	ABC-type sugar transport system, permease component
G3260_RS32965	COG4209	transmembrane transport
G3260_RS32975	COG1609	Transcriptional regulator
G3260_RS33010	COG1957	nucleoside hydrolase
G3260_RS33020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3260_RS33065	COG1695	Transcriptional regulator
G3260_RS33115	COG1278	Cold shock
G3260_RS33120	COG0513	Belongs to the DEAD box helicase family
G3260_RS33145	COG0477	Major facilitator Superfamily
G3260_RS33160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3260_RS33175	COG0577	efflux transmembrane transporter activity
G3260_RS33180	COG1136	(ABC) transporter
G3260_RS33185	COG2197	response regulator
G3260_RS33190	COG4585	Histidine kinase
G3260_RS33195	COG1136	(ABC) transporter
G3260_RS33195	COG0577	efflux transmembrane transporter activity
G3260_RS33250	COG0583	DNA-binding transcription factor activity
G3260_RS33260	COG2226	methyltransferase
G3260_RS33285	COG0596	Alpha beta hydrolase
G3260_RS33315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G3260_RS33355	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS33360	COG1063	alcohol dehydrogenase
G3260_RS33370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3260_RS33465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3260_RS33510	COG4221	oxidoreductase activity
G3260_RS33530	COG1131	(ABC) transporter
G3260_RS33575	COG1309	transcriptional regulator
G3260_RS33600	COG2222	sugar isomerase
G3260_RS33605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3260_RS33620	COG0477	Major facilitator Superfamily
G3260_RS33630	COG1028	Short-chain dehydrogenase reductase Sdr
G3260_RS33655	COG0009	L-threonylcarbamoyladenylate synthase
G3260_RS34005	COG1132	(ABC) transporter