locus-tag	class	description
XNR_RS00040	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNR_RS00045	COG3246	L-lysine catabolic process to acetate
XNR_RS00075	COG0477	Major facilitator Superfamily
XNR_RS00100	COG4335	DNA alkylation repair
XNR_RS00115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XNR_RS00130	COG1349	DNA-binding transcription factor activity
XNR_RS00140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XNR_RS00140	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
XNR_RS00140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XNR_RS00145	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XNR_RS00145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XNR_RS00150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XNR_RS00205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XNR_RS00235	COG1695	Transcriptional regulator
XNR_RS00260	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS00275	COG0513	Belongs to the DEAD box helicase family
XNR_RS00285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
XNR_RS00300	COG0633	Ferredoxin
XNR_RS00300	COG3217	Mosc domain protein beta barrel domain protein
XNR_RS00320	COG1349	DNA-binding transcription factor activity
XNR_RS00340	COG1940	carbohydrate kinase activity
XNR_RS00350	COG2223	nitrite transmembrane transporter activity
XNR_RS00365	COG2197	response regulator
XNR_RS00380	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XNR_RS00405	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
XNR_RS00445	COG0584	glycerophosphoryl diester phosphodiesterase
XNR_RS00460	COG1846	Transcriptional regulator
XNR_RS00480	COG0671	phosphoesterase, PA-phosphatase related
XNR_RS00510	COG2233	PERMEase
XNR_RS00515	COG0640	Transcriptional regulator
XNR_RS00520	COG1902	pentaerythritol trinitrate reductase activity
XNR_RS00535	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XNR_RS00550	COG2706	6-phosphogluconolactonase activity
XNR_RS00565	COG0071	Belongs to the small heat shock protein (HSP20) family
XNR_RS00570	COG0076	glutamate decarboxylase activity
XNR_RS00575	COG0243	molybdopterin cofactor binding
XNR_RS00590	COG0303	'Molybdopterin
XNR_RS00595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XNR_RS00610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XNR_RS00615	COG0583	DNA-binding transcription factor activity
XNR_RS00660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XNR_RS00665	COG1120	ATPase activity
XNR_RS00670	COG2207	Transcriptional regulator
XNR_RS00675	COG2814	Major facilitator Superfamily
XNR_RS00700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XNR_RS00715	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
XNR_RS00735	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XNR_RS00755	COG0477	Major facilitator Superfamily
XNR_RS00760	COG1309	transcriptional regulator
XNR_RS00770	COG1472	Belongs to the glycosyl hydrolase 3 family
XNR_RS00780	COG1175	transmembrane transport
XNR_RS00790	COG1609	Transcriptional regulator
XNR_RS00795	COG0432	Pfam Uncharacterised protein family UPF0047
XNR_RS00800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XNR_RS00805	COG1116	anion transmembrane transporter activity
XNR_RS00815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNR_RS00820	COG0492	ferredoxin-NADP+ reductase activity
XNR_RS00825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XNR_RS00830	COG1132	(ABC) transporter
XNR_RS00850	COG1132	(ABC) transporter
XNR_RS00855	COG1132	(ABC) transporter
XNR_RS00870	COG1946	Acyl-CoA thioesterase
XNR_RS00885	COG2018	Roadblock/LC7 domain
XNR_RS00930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XNR_RS00975	COG2124	cytochrome p450
XNR_RS00980	COG2130	NADP-dependent
XNR_RS00985	COG1233	COG1233 Phytoene dehydrogenase and related
XNR_RS01055	COG0477	Major facilitator Superfamily
XNR_RS01065	COG0583	DNA-binding transcription factor activity
XNR_RS01070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
XNR_RS01075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
XNR_RS01080	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNR_RS01085	COG1960	acyl-CoA dehydrogenase activity
XNR_RS01090	COG2391	methyltransferase activity
XNR_RS01135	COG0740	serine-type endopeptidase activity
XNR_RS01140	COG0740	serine-type endopeptidase activity
XNR_RS01175	COG4521	taurine ABC transporter
XNR_RS01180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XNR_RS01200	COG3959	Transketolase, thiamine diphosphate binding domain
XNR_RS01205	COG3958	Transketolase
XNR_RS01275	COG2755	lipolytic protein G-D-S-L family
XNR_RS01280	COG2365	Tyrosine phosphatase family
XNR_RS01310	COG1657	PFAM Prenyltransferase squalene oxidase
XNR_RS01320	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
XNR_RS01330	COG1562	ergosterol biosynthetic process
XNR_RS01335	COG1388	LysM domain
XNR_RS01335	COG1134	teichoic acid transport
XNR_RS01360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
XNR_RS01375	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
XNR_RS01390	COG1024	Enoyl-CoA hydratase
XNR_RS01405	COG2183	response to ionizing radiation
XNR_RS01420	COG1802	Transcriptional regulator
XNR_RS01425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XNR_RS01430	COG0402	S-adenosylhomocysteine deaminase activity
XNR_RS01455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XNR_RS01460	COG0789	Transcriptional regulator
XNR_RS01465	COG1024	Enoyl-CoA hydratase
XNR_RS01465	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNR_RS01470	COG0183	Belongs to the thiolase family
XNR_RS01480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XNR_RS01485	COG1683	Conserved Protein
XNR_RS01490	COG1515	deoxyribonuclease V activity
XNR_RS01520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XNR_RS01530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XNR_RS01530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XNR_RS01540	COG0488	(ABC) transporter
XNR_RS01560	COG0438	transferase activity, transferring glycosyl groups
XNR_RS01595	COG0254	rRNA binding
XNR_RS01610	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XNR_RS01620	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XNR_RS01645	COG1793	dna ligase
XNR_RS01650	COG1024	Enoyl-CoA hydratase
XNR_RS01685	COG0789	Transcriptional regulator
XNR_RS01730	COG1846	Transcriptional regulator
XNR_RS01790	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS01810	COG2814	Major facilitator Superfamily
XNR_RS01815	COG2259	Doxx family
XNR_RS01825	COG1869	D-ribose catabolic process
XNR_RS01830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XNR_RS01835	COG1172	Belongs to the binding-protein-dependent transport system permease family
XNR_RS01840	COG1129	ABC transporter
XNR_RS01845	COG1609	Transcriptional regulator
XNR_RS01865	COG1295	ribonuclease BN
XNR_RS01930	COG0673	inositol 2-dehydrogenase activity
XNR_RS01940	COG1172	Belongs to the binding-protein-dependent transport system permease family
XNR_RS01945	COG1129	ABC transporter
XNR_RS01950	COG1940	carbohydrate kinase activity
XNR_RS01955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XNR_RS01965	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XNR_RS01975	COG0583	DNA-binding transcription factor activity
XNR_RS01980	COG1115	amino acid carrier protein
XNR_RS02005	COG2154	pterin-4-alpha-carbinolamine dehydratase
XNR_RS02035	COG1140	nitrate reductase beta subunit
XNR_RS02090	COG0693	protein deglycase activity
XNR_RS02100	COG1597	lipid kinase activity
XNR_RS02105	COG4106	trans-aconitate 2-methyltransferase activity
XNR_RS02120	COG3226	Transcriptional regulator
XNR_RS02130	COG0604	alcohol dehydrogenase
XNR_RS02145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XNR_RS02165	COG1619	proteins homologs of microcin C7 resistance protein MccF
XNR_RS02175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XNR_RS02200	COG0596	Alpha beta hydrolase
XNR_RS02220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS02225	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS02230	COG1120	ATPase activity
XNR_RS02235	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNR_RS02245	COG0604	alcohol dehydrogenase
XNR_RS02250	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XNR_RS02250	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XNR_RS02255	COG2301	Belongs to the HpcH HpaI aldolase family
XNR_RS02270	COG0688	phosphatidylethanolamine metabolic process
XNR_RS02280	COG1929	Belongs to the glycerate kinase type-1 family
XNR_RS02285	COG0488	(ABC) transporter
XNR_RS02295	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XNR_RS02300	COG0702	epimerase
XNR_RS02305	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS02315	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
XNR_RS02340	COG0159	tryptophan synthase activity
XNR_RS02355	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
XNR_RS02375	COG0483	inositol monophosphate 1-phosphatase activity
XNR_RS02385	COG0095	Lipoate-protein ligase
XNR_RS02405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XNR_RS02430	COG0405	Gamma-glutamyltransferase
XNR_RS02460	COG0765	amino acid transport
XNR_RS02465	COG0765	amino acid transport
XNR_RS02470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XNR_RS02475	COG1126	abc transporter atp-binding protein
XNR_RS02505	COG1228	amidohydrolase
XNR_RS02510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XNR_RS02525	COG1960	acyl-CoA dehydrogenase activity
XNR_RS02555	COG5183	chlorophyll binding
XNR_RS02555	COG2133	pyrroloquinoline quinone binding
XNR_RS02560	COG1132	(ABC) transporter
XNR_RS02565	COG1132	(ABC) transporter
XNR_RS02570	COG1120	ATPase activity
XNR_RS02575	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS02580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS02585	COG2375	cellular response to nickel ion
XNR_RS02590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XNR_RS02595	COG2207	Transcriptional regulator
XNR_RS02625	COG2197	response regulator
XNR_RS02635	COG0464	growth
XNR_RS02710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XNR_RS02720	COG1940	carbohydrate kinase activity
XNR_RS02730	COG1172	Belongs to the binding-protein-dependent transport system permease family
XNR_RS02740	COG2188	Transcriptional regulator
XNR_RS02745	COG0673	inositol 2-dehydrogenase activity
XNR_RS02760	COG2197	response regulator
XNR_RS02765	COG4585	Histidine kinase
XNR_RS02780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XNR_RS02785	COG1414	Transcriptional regulator
XNR_RS02800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XNR_RS02805	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
XNR_RS02810	COG2080	2 iron, 2 sulfur cluster binding
XNR_RS02815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XNR_RS02830	COG0667	Aldo Keto reductase
XNR_RS02840	COG1960	acyl-CoA dehydrogenase activity
XNR_RS02850	COG0235	Class ii aldolase
XNR_RS02880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XNR_RS02890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XNR_RS02895	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS02920	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
XNR_RS02935	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS02960	COG1819	glycosyl
XNR_RS02965	COG2124	cytochrome p450
XNR_RS02975	COG0022	dehydrogenase e1 component
XNR_RS02980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
XNR_RS02985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XNR_RS03000	COG0656	L-ascorbic acid biosynthetic process
XNR_RS03010	COG2197	response regulator
XNR_RS03015	COG1309	transcriptional regulator
XNR_RS03030	COG4941	Belongs to the sigma-70 factor family
XNR_RS03035	COG3795	YCII-related domain
XNR_RS03040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XNR_RS03045	COG1621	beta-fructofuranosidase activity
XNR_RS03065	COG1609	Transcriptional regulator
XNR_RS03110	COG2233	PERMEase
XNR_RS03125	COG2351	hydroxyisourate hydrolase activity
XNR_RS03145	COG3622	Belongs to the hyi family
XNR_RS03150	COG2084	Dehydrogenase
XNR_RS03155	COG0753	catalase activity
XNR_RS03160	COG3960	tartronate-semialdehyde synthase activity
XNR_RS03170	COG0318	PFAM AMP-dependent synthetase and ligase
XNR_RS03175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XNR_RS03180	COG2197	response regulator
XNR_RS03190	COG1309	transcriptional regulator
XNR_RS03230	COG2252	PERMEase
XNR_RS03235	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XNR_RS03250	COG3835	regulator
XNR_RS03255	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
XNR_RS03265	COG1802	Transcriptional regulator
XNR_RS03280	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS03295	COG0028	Belongs to the TPP enzyme family
XNR_RS03315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XNR_RS03320	COG1162	GTPase activity
XNR_RS03330	COG2365	Tyrosine phosphatase family
XNR_RS03370	COG1595	DNA-templated transcription, initiation
XNR_RS03380	COG0789	Transcriptional regulator
XNR_RS03390	COG0702	epimerase
XNR_RS03395	COG1846	Transcriptional regulator
XNR_RS03400	COG2409	Drug exporters of the RND superfamily
XNR_RS03410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS03415	COG1120	ATPase activity
XNR_RS03425	COG2255	four-way junction helicase activity
XNR_RS03450	COG2040	homocysteine
XNR_RS03470	COG1960	acyl-CoA dehydrogenase activity
XNR_RS03475	COG0604	alcohol dehydrogenase
XNR_RS03485	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XNR_RS03500	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XNR_RS03510	COG0175	sulfate reduction
XNR_RS03515	COG0529	Catalyzes the synthesis of activated sulfate
XNR_RS03540	COG1116	anion transmembrane transporter activity
XNR_RS03545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XNR_RS03560	COG0386	Belongs to the glutathione peroxidase family
XNR_RS03595	COG5002	protein histidine kinase activity
XNR_RS03595	COG2176	DNA-directed DNA polymerase activity
XNR_RS03660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XNR_RS03665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XNR_RS03685	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
XNR_RS03690	COG1595	DNA-templated transcription, initiation
XNR_RS03705	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS03715	COG0726	polysaccharide deacetylase
XNR_RS03725	COG3220	belongs to the UPF0276 family
XNR_RS03735	COG3253	May function as heme-dependent peroxidase
XNR_RS03740	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
XNR_RS03750	COG0446	pyridine nucleotide-disulphide oxidoreductase
XNR_RS03755	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XNR_RS03775	COG0183	Belongs to the thiolase family
XNR_RS03780	COG1024	Enoyl-CoA hydratase
XNR_RS03780	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNR_RS03800	COG0531	amino acid
XNR_RS03805	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XNR_RS03810	COG4214	carbohydrate transport
XNR_RS03820	COG4213	ABC transporter substrate-binding protein
XNR_RS03830	COG0395	ABC-type sugar transport system, permease component
XNR_RS03835	COG1175	transmembrane transport
XNR_RS03840	COG1653	transport
XNR_RS03845	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
XNR_RS03870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XNR_RS03920	COG1120	ATPase activity
XNR_RS03925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS03930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XNR_RS03950	COG2235	arginine
XNR_RS03955	COG1320	monovalent cation:proton antiporter activity
XNR_RS03970	COG0651	ATP synthesis coupled electron transport
XNR_RS03975	COG1006	Multisubunit Na H antiporter MnhC subunit
XNR_RS03980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XNR_RS03980	COG2111	Na H antiporter
XNR_RS03990	COG2124	cytochrome p450
XNR_RS04020	COG0531	amino acid
XNR_RS04025	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XNR_RS04030	COG2235	arginine
XNR_RS04050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XNR_RS04055	COG2890	protein-(glutamine-N5) methyltransferase activity
XNR_RS04085	COG1799	cell septum assembly
XNR_RS04095	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
XNR_RS04110	COG1556	Lactate utilization protein
XNR_RS04115	COG1139	Iron-sulfur cluster binding protein
XNR_RS04120	COG0247	lactate metabolic process
XNR_RS04125	COG1620	l-lactate permease
XNR_RS04135	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XNR_RS04175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XNR_RS04185	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XNR_RS04200	COG1120	ATPase activity
XNR_RS04205	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS04210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS04220	COG1733	regulation of RNA biosynthetic process
XNR_RS04240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNR_RS04245	COG0601	transmembrane transport
XNR_RS04255	COG0747	negative chemotaxis
XNR_RS04265	COG1309	transcriptional regulator
XNR_RS04280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XNR_RS04295	COG2936	dipeptidyl-peptidase activity
XNR_RS04315	COG3540	Alkaline phosphatase
XNR_RS04325	COG2050	protein possibly involved in aromatic compounds catabolism
XNR_RS04340	COG0789	Transcriptional regulator
XNR_RS04345	COG0640	Transcriptional regulator
XNR_RS04365	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XNR_RS04415	COG0438	transferase activity, transferring glycosyl groups
XNR_RS04420	COG3226	Transcriptional regulator
XNR_RS04425	COG0738	Major facilitator superfamily
XNR_RS04440	COG4213	ABC transporter substrate-binding protein
XNR_RS04445	COG1172	Belongs to the binding-protein-dependent transport system permease family
XNR_RS04450	COG1172	Belongs to the binding-protein-dependent transport system permease family
XNR_RS04455	COG1129	ABC transporter
XNR_RS04460	COG1846	Transcriptional regulator
XNR_RS04460	COG1940	carbohydrate kinase activity
XNR_RS04465	COG0252	asparaginase activity
XNR_RS04475	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS04495	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS04510	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS04545	COG0473	3-isopropylmalate dehydrogenase activity
XNR_RS04560	COG0656	L-ascorbic acid biosynthetic process
XNR_RS04595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XNR_RS04620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XNR_RS04630	COG1127	ABC transporter
XNR_RS04665	COG0583	DNA-binding transcription factor activity
XNR_RS04675	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
XNR_RS04690	COG4221	oxidoreductase activity
XNR_RS04695	COG0300	oxidoreductase activity
XNR_RS04755	COG2233	PERMEase
XNR_RS04760	COG0402	S-adenosylhomocysteine deaminase activity
XNR_RS04775	COG0559	Belongs to the binding-protein-dependent transport system permease family
XNR_RS04810	COG0395	ABC-type sugar transport system, permease component
XNR_RS04815	COG1063	alcohol dehydrogenase
XNR_RS04830	COG0438	transferase activity, transferring glycosyl groups
XNR_RS04835	COG2197	response regulator
XNR_RS04845	COG1136	(ABC) transporter
XNR_RS04855	COG2197	response regulator
XNR_RS04865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XNR_RS04875	COG3251	PFAM MbtH domain protein
XNR_RS04885	COG2175	clavaminate synthase activity
XNR_RS04915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XNR_RS04920	COG0531	amino acid
XNR_RS04925	COG0569	domain protein
XNR_RS04955	COG1136	(ABC) transporter
XNR_RS04975	COG0756	dUTP diphosphatase activity
XNR_RS05000	COG2205	protein histidine kinase activity
XNR_RS05005	COG0745	RESPONSE REGULATOR receiver
XNR_RS05010	COG0483	inositol monophosphate 1-phosphatase activity
XNR_RS05015	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XNR_RS05065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XNR_RS05075	COG1802	Transcriptional regulator
XNR_RS05090	COG0612	Peptidase, M16
XNR_RS05095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XNR_RS05105	COG0366	Alpha amylase catalytic
XNR_RS05110	COG0395	ABC-type sugar transport system, permease component
XNR_RS05115	COG1175	transmembrane transport
XNR_RS05120	COG1653	transport
XNR_RS05135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XNR_RS05170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XNR_RS05175	COG1802	Transcriptional regulator
XNR_RS05210	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XNR_RS05225	COG0588	phosphoglycerate mutase activity
XNR_RS05245	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XNR_RS05250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XNR_RS05255	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XNR_RS05295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XNR_RS05305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XNR_RS05310	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XNR_RS05320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XNR_RS05340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XNR_RS05350	COG2205	protein histidine kinase activity
XNR_RS05355	COG0745	RESPONSE REGULATOR receiver
XNR_RS05360	COG1126	abc transporter atp-binding protein
XNR_RS05365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XNR_RS05370	COG0765	amino acid transport
XNR_RS05375	COG0765	amino acid transport
XNR_RS05380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XNR_RS05400	COG2137	regulation of response to DNA damage stimulus
XNR_RS05405	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XNR_RS05430	COG0628	permease
XNR_RS05455	COG1201	RNA secondary structure unwinding
XNR_RS05460	COG0596	Alpha beta hydrolase
XNR_RS05480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XNR_RS05490	COG0783	Belongs to the Dps family
XNR_RS05495	COG1396	sequence-specific DNA binding
XNR_RS05500	COG1058	Belongs to the CinA family
XNR_RS05500	COG1546	Belongs to the CinA family
XNR_RS05510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XNR_RS05520	COG1674	ftsk spoiiie
XNR_RS05530	COG4999	Histidine kinase
XNR_RS05530	COG3850	Histidine kinase
XNR_RS05530	COG3437	response regulator, receiver
XNR_RS05530	COG2205	protein histidine kinase activity
XNR_RS05535	COG2208	phosphoserine phosphatase activity
XNR_RS05535	COG2770	Histidine kinase
XNR_RS05565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
XNR_RS05570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XNR_RS05575	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
XNR_RS05595	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XNR_RS05600	COG0612	Peptidase, M16
XNR_RS05605	COG1185	polyribonucleotide nucleotidyltransferase activity
XNR_RS05610	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XNR_RS05620	COG0455	bacterial-type flagellum organization
XNR_RS05625	COG0747	negative chemotaxis
XNR_RS05630	COG0601	transmembrane transport
XNR_RS05635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNR_RS05640	COG0444	Belongs to the ABC transporter superfamily
XNR_RS05645	COG4608	Belongs to the ABC transporter superfamily
XNR_RS05650	COG1357	PFAM Pentapeptide repeats (8 copies)
XNR_RS05670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XNR_RS05675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XNR_RS05685	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XNR_RS05700	COG0779	Required for maturation of 30S ribosomal subunits
XNR_RS05720	COG0442	prolyl-tRNA aminoacylation
XNR_RS05740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNR_RS05745	COG0601	transmembrane transport
XNR_RS05750	COG0747	negative chemotaxis
XNR_RS05765	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XNR_RS05770	COG0750	zinc metalloprotease
XNR_RS05775	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XNR_RS05785	COG1940	carbohydrate kinase activity
XNR_RS05790	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS05795	COG2508	Transcriptional regulator
XNR_RS05825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XNR_RS05830	COG1177	transmembrane transport
XNR_RS05835	COG1176	ABC-type spermidine putrescine transport system, permease component I
XNR_RS05840	COG3842	ATPase activity
XNR_RS05850	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS05865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XNR_RS05885	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS05895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XNR_RS05920	COG3842	ATPase activity
XNR_RS05925	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XNR_RS05935	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XNR_RS05945	COG0233	cytoplasmic translational termination
XNR_RS05950	COG0528	UMP kinase activity
XNR_RS05955	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XNR_RS05960	COG0052	Belongs to the universal ribosomal protein uS2 family
XNR_RS05970	COG1191	sigma factor activity
XNR_RS05985	COG0792	nuclease activity
XNR_RS06000	COG0681	Belongs to the peptidase S26 family
XNR_RS06005	COG0681	Belongs to the peptidase S26 family
XNR_RS06010	COG0681	Belongs to the peptidase S26 family
XNR_RS06015	COG0681	Belongs to the peptidase S26 family
XNR_RS06020	COG0335	large ribosomal subunit rRNA binding
XNR_RS06025	COG0336	Belongs to the RNA methyltransferase TrmD family
XNR_RS06030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XNR_RS06035	COG1837	Belongs to the UPF0109 family
XNR_RS06040	COG0228	four-way junction DNA binding
XNR_RS06055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XNR_RS06065	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XNR_RS06095	COG0477	Major facilitator Superfamily
XNR_RS06100	COG1196	nuclear chromosome segregation
XNR_RS06110	COG1254	Belongs to the acylphosphatase family
XNR_RS06115	COG2340	Cysteine-rich secretory protein family
XNR_RS06120	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XNR_RS06125	COG0571	ribonuclease III activity
XNR_RS06130	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XNR_RS06145	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XNR_RS06150	COG0742	ribosomal rna small subunit methyltransferase
XNR_RS06160	COG1461	Dihydroxyacetone kinase
XNR_RS06165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XNR_RS06170	COG0351	phosphomethylpyrimidine kinase
XNR_RS06190	COG1181	Belongs to the D-alanine--D-alanine ligase family
XNR_RS06195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XNR_RS06205	COG1920	GTP binding
XNR_RS06215	COG0776	regulation of translation
XNR_RS06225	COG0066	3-isopropylmalate dehydratase activity
XNR_RS06230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XNR_RS06235	COG1414	Transcriptional regulator
XNR_RS06280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XNR_RS06285	COG0179	Fumarylacetoacetate (FAA) hydrolase
XNR_RS06300	COG2018	Roadblock/LC7 domain
XNR_RS06320	COG2018	Roadblock/LC7 domain
XNR_RS06340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XNR_RS06350	COG2353	YceI-like domain
XNR_RS06390	COG0789	Transcriptional regulator
XNR_RS06410	COG4221	oxidoreductase activity
XNR_RS06440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XNR_RS06445	COG0477	Major facilitator Superfamily
XNR_RS06450	COG2957	Belongs to the agmatine deiminase family
XNR_RS06455	COG0804	urea catabolic process
XNR_RS06460	COG0832	Belongs to the urease beta subunit family
XNR_RS06460	COG0831	urea catabolic process
XNR_RS06465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XNR_RS06470	COG0473	3-isopropylmalate dehydrogenase activity
XNR_RS06495	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS06500	COG0506	proline dehydrogenase activity
XNR_RS06505	COG3835	regulator
XNR_RS06525	COG2890	protein-(glutamine-N5) methyltransferase activity
XNR_RS06535	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XNR_RS06540	COG0440	acetolactate synthase activity
XNR_RS06560	COG0667	Aldo Keto reductase
XNR_RS06565	COG2133	pyrroloquinoline quinone binding
XNR_RS06580	COG2197	response regulator
XNR_RS06595	COG2409	Drug exporters of the RND superfamily
XNR_RS06600	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XNR_RS06610	COG0154	amidase activity
XNR_RS06615	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
XNR_RS06625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XNR_RS06635	COG4221	oxidoreductase activity
XNR_RS06655	COG0482	sulfurtransferase activity
XNR_RS06680	COG2860	membrane
XNR_RS06685	COG4608	Belongs to the ABC transporter superfamily
XNR_RS06690	COG0444	Belongs to the ABC transporter superfamily
XNR_RS06695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNR_RS06700	COG0601	transmembrane transport
XNR_RS06705	COG0747	negative chemotaxis
XNR_RS06725	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XNR_RS06730	COG0509	glycine decarboxylation via glycine cleavage system
XNR_RS06735	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XNR_RS06740	COG1760	l-serine dehydratase
XNR_RS06755	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XNR_RS06760	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XNR_RS06765	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XNR_RS06780	COG0477	Major facilitator Superfamily
XNR_RS06795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XNR_RS06820	COG2085	NADP oxidoreductase coenzyme F420-dependent
XNR_RS06845	COG1376	ErfK ybiS ycfS ynhG family protein
XNR_RS06870	COG1132	(ABC) transporter
XNR_RS06875	COG1132	(ABC) transporter
XNR_RS06885	COG1733	regulation of RNA biosynthetic process
XNR_RS06905	COG0366	Alpha amylase catalytic
XNR_RS06910	COG0366	Alpha amylase catalytic
XNR_RS06915	COG3281	Trehalose synthase
XNR_RS06920	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XNR_RS06935	COG1119	ATPase activity
XNR_RS06940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XNR_RS06955	COG1301	dicarboxylic acid transport
XNR_RS06960	COG3290	protein histidine kinase activity
XNR_RS06965	COG4565	transcriptional regulatory protein
XNR_RS06970	COG0205	6-phosphofructokinase activity
XNR_RS06975	COG0280	phosphate acetyltransferase
XNR_RS06975	COG0857	belongs to the CobB CobQ family
XNR_RS06980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
XNR_RS07025	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XNR_RS07025	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XNR_RS07100	COG1335	isochorismatase
XNR_RS07130	COG0183	Belongs to the thiolase family
XNR_RS07150	COG1131	(ABC) transporter
XNR_RS07185	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
XNR_RS07200	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNR_RS07215	COG4585	Histidine kinase
XNR_RS07220	COG2197	response regulator
XNR_RS07240	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XNR_RS07245	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XNR_RS07250	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XNR_RS07255	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XNR_RS07260	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XNR_RS07265	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XNR_RS07270	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XNR_RS07285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XNR_RS07290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XNR_RS07300	COG2890	protein-(glutamine-N5) methyltransferase activity
XNR_RS07305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XNR_RS07310	COG0254	rRNA binding
XNR_RS07315	COG1316	TRANSCRIPTIONal
XNR_RS07325	COG0083	homoserine kinase activity
XNR_RS07330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
XNR_RS07335	COG0460	homoserine dehydrogenase
XNR_RS07340	COG0019	diaminopimelate decarboxylase activity
XNR_RS07345	COG0018	arginyl-trna synthetase
XNR_RS07370	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS07380	COG1191	sigma factor activity
XNR_RS07385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XNR_RS07385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XNR_RS07395	COG2267	carboxylic ester hydrolase activity
XNR_RS07400	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
XNR_RS07415	COG0772	Belongs to the SEDS family
XNR_RS07490	COG0726	polysaccharide deacetylase
XNR_RS07495	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XNR_RS07500	COG0477	Major facilitator Superfamily
XNR_RS07515	COG1595	DNA-templated transcription, initiation
XNR_RS07525	COG1131	(ABC) transporter
XNR_RS07545	COG0745	RESPONSE REGULATOR receiver
XNR_RS07550	COG2205	protein histidine kinase activity
XNR_RS07555	COG0567	Dehydrogenase, E1 component
XNR_RS07555	COG0508	dehydrogenase complex catalyzes the overall conversion of
XNR_RS07585	COG2255	four-way junction helicase activity
XNR_RS07630	COG0604	alcohol dehydrogenase
XNR_RS07635	COG0281	malic enzyme
XNR_RS07650	COG1126	abc transporter atp-binding protein
XNR_RS07655	COG4106	trans-aconitate 2-methyltransferase activity
XNR_RS07705	COG0142	geranyltranstransferase activity
XNR_RS07715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XNR_RS07720	COG1959	2 iron, 2 sulfur cluster binding
XNR_RS07740	COG2515	1-aminocyclopropane-1-carboxylate deaminase
XNR_RS07755	COG2172	sigma factor antagonist activity
XNR_RS07770	COG1597	lipid kinase activity
XNR_RS07790	COG0363	glucosamine-6-phosphate deaminase activity
XNR_RS07795	COG1472	Belongs to the glycosyl hydrolase 3 family
XNR_RS07800	COG0395	ABC-type sugar transport system, permease component
XNR_RS07805	COG1175	transmembrane transport
XNR_RS07810	COG2182	Extracellular solute-binding protein
XNR_RS07815	COG2188	Transcriptional regulator
XNR_RS07820	COG1966	Carbon starvation protein
XNR_RS07840	COG2124	cytochrome p450
XNR_RS07850	COG0242	peptide deformylase activity
XNR_RS07860	COG5662	AntiSigma factor
XNR_RS07865	COG1595	DNA-templated transcription, initiation
XNR_RS07875	COG2135	peptidase activity
XNR_RS07885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XNR_RS07895	COG2076	Multidrug Resistance protein
XNR_RS07905	COG0483	inositol monophosphate 1-phosphatase activity
XNR_RS07910	COG0753	catalase activity
XNR_RS07935	COG1615	UPF0182 protein
XNR_RS07945	COG3480	Lon protease (S16) C-terminal proteolytic domain
XNR_RS08000	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XNR_RS08040	COG0210	DNA helicase
XNR_RS08130	COG0513	Belongs to the DEAD box helicase family
XNR_RS08140	COG1432	Conserved Protein
XNR_RS08145	COG2095	MarC family integral membrane protein
XNR_RS08150	COG0613	PHP domain protein
XNR_RS08155	COG2814	Major facilitator Superfamily
XNR_RS08165	COG0598	Magnesium transport protein CorA
XNR_RS08205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XNR_RS08210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XNR_RS08220	COG1595	DNA-templated transcription, initiation
XNR_RS08230	COG1024	Enoyl-CoA hydratase
XNR_RS08240	COG0519	Catalyzes the synthesis of GMP from XMP
XNR_RS08275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XNR_RS08305	COG0456	acetyltransferase
XNR_RS08310	COG2912	Transglutaminase-like superfamily
XNR_RS08320	COG1609	Transcriptional regulator
XNR_RS08325	COG1172	Belongs to the binding-protein-dependent transport system permease family
XNR_RS08335	COG1129	ABC transporter
XNR_RS08340	COG1879	ABC-type sugar transport system periplasmic component
XNR_RS08350	COG3250	beta-galactosidase activity
XNR_RS08370	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XNR_RS08395	COG4608	Belongs to the ABC transporter superfamily
XNR_RS08405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNR_RS08410	COG0601	transmembrane transport
XNR_RS08420	COG4608	Belongs to the ABC transporter superfamily
XNR_RS08425	COG0444	Belongs to the ABC transporter superfamily
XNR_RS08430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNR_RS08435	COG0601	transmembrane transport
XNR_RS08445	COG1217	gtp-binding protein TYPA
XNR_RS08495	COG1554	hydrolase, family 65, central catalytic
XNR_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS08555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNR_RS08565	COG3473	Maleate cis-trans isomerase
XNR_RS08585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XNR_RS08590	COG0765	amino acid transport
XNR_RS08595	COG0765	amino acid transport
XNR_RS08600	COG1126	abc transporter atp-binding protein
XNR_RS08630	COG3397	chitin binding
XNR_RS08685	COG0673	inositol 2-dehydrogenase activity
XNR_RS08690	COG0179	Fumarylacetoacetate (FAA) hydrolase
XNR_RS08695	COG0706	membrane insertase activity
XNR_RS08740	COG2271	Major facilitator Superfamily
XNR_RS08750	COG2733	membrane
XNR_RS08780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XNR_RS08790	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XNR_RS08815	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XNR_RS08825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XNR_RS08830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XNR_RS08835	COG1263	PTS System
XNR_RS08845	COG1234	tRNA 3'-trailer cleavage
XNR_RS08865	COG1113	amino acid transport
XNR_RS08880	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XNR_RS08890	COG1335	isochorismatase
XNR_RS08925	COG0277	FAD linked oxidase domain protein
XNR_RS08935	COG3185	4-Hydroxyphenylpyruvate dioxygenase
XNR_RS08945	COG1174	glycine betaine transport
XNR_RS08950	COG0517	IMP dehydrogenase activity
XNR_RS08950	COG1125	glycine betaine transport
XNR_RS08955	COG1174	glycine betaine transport
XNR_RS09000	COG1116	anion transmembrane transporter activity
XNR_RS09040	COG2318	DinB family
XNR_RS09065	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XNR_RS09090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XNR_RS09105	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XNR_RS09110	COG0395	ABC-type sugar transport system, permease component
XNR_RS09115	COG1175	transmembrane transport
XNR_RS09130	COG1678	Uncharacterized ACR, COG1678
XNR_RS09135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XNR_RS09140	COG0776	regulation of translation
XNR_RS09150	COG3973	AAA domain
XNR_RS09150	COG3973	AAA domain
XNR_RS09195	COG0583	DNA-binding transcription factor activity
XNR_RS09205	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XNR_RS09210	COG0793	Belongs to the peptidase S41A family
XNR_RS09220	COG2884	Cell division ATP-binding protein ftsE
XNR_RS09235	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XNR_RS09240	COG0515	serine threonine protein kinase
XNR_RS09245	COG0515	serine threonine protein kinase
XNR_RS09250	COG1716	ATPase activity
XNR_RS09255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
XNR_RS09260	COG1653	transport
XNR_RS09265	COG1175	transmembrane transport
XNR_RS09270	COG0395	ABC-type sugar transport system, permease component
XNR_RS09275	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
XNR_RS09280	COG0438	transferase activity, transferring glycosyl groups
XNR_RS09285	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
XNR_RS09290	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
XNR_RS09300	COG2226	methyltransferase
XNR_RS09315	COG2902	Dehydrogenase
XNR_RS09335	COG0583	DNA-binding transcription factor activity
XNR_RS09350	COG0653	protein targeting
XNR_RS09355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XNR_RS09360	COG3214	Protein conserved in bacteria
XNR_RS09365	COG2197	response regulator
XNR_RS09370	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
XNR_RS09380	COG0823	Involved in the tonB-independent uptake of proteins
XNR_RS09385	COG5002	protein histidine kinase activity
XNR_RS09390	COG0745	RESPONSE REGULATOR receiver
XNR_RS09395	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XNR_RS09415	COG0714	Associated with various cellular activities
XNR_RS09420	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
XNR_RS09455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
XNR_RS09465	COG1482	cell wall glycoprotein biosynthetic process
XNR_RS09475	COG2835	tetraacyldisaccharide 4'-kinase activity
XNR_RS09485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XNR_RS09495	COG1620	l-lactate permease
XNR_RS09530	COG0391	Required for morphogenesis under gluconeogenic growth conditions
XNR_RS09535	COG0778	Nitroreductase
XNR_RS09535	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
XNR_RS09565	COG1316	TRANSCRIPTIONal
XNR_RS09585	COG1316	TRANSCRIPTIONal
XNR_RS09590	COG3046	protein related to deoxyribodipyrimidine photolyase
XNR_RS09640	COG0753	catalase activity
XNR_RS09680	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
XNR_RS09690	COG2072	flavoprotein involved in K transport
XNR_RS09715	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
XNR_RS09730	COG2205	protein histidine kinase activity
XNR_RS09735	COG0745	RESPONSE REGULATOR receiver
XNR_RS09740	COG3104	oligopeptide transport
XNR_RS09750	COG1366	Belongs to the anti-sigma-factor antagonist family
XNR_RS09755	COG1191	sigma factor activity
XNR_RS09760	COG1228	amidohydrolase
XNR_RS09770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XNR_RS09790	COG0395	ABC-type sugar transport system, permease component
XNR_RS09850	COG2755	lipolytic protein G-D-S-L family
XNR_RS09855	COG0183	Belongs to the thiolase family
XNR_RS09875	COG1476	TRANSCRIPTIONal
XNR_RS09890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
XNR_RS09900	COG1136	(ABC) transporter
XNR_RS09905	COG0577	efflux transmembrane transporter activity
XNR_RS09905	COG1136	(ABC) transporter
XNR_RS09910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XNR_RS09915	COG1252	NADH dehydrogenase
XNR_RS09945	COG0148	phosphopyruvate hydratase activity
XNR_RS09960	COG2124	cytochrome p450
XNR_RS10000	COG1733	regulation of RNA biosynthetic process
XNR_RS10035	COG0154	amidase activity
XNR_RS10040	COG3226	Transcriptional regulator
XNR_RS10050	COG1473	amidohydrolase
XNR_RS10105	COG3629	intracellular signal transduction
XNR_RS10105	COG3903	Transcriptional regulator
XNR_RS10115	COG0477	Major facilitator Superfamily
XNR_RS10155	COG0596	Alpha beta hydrolase
XNR_RS10165	COG1316	TRANSCRIPTIONal
XNR_RS10185	COG0789	Transcriptional regulator
XNR_RS10210	COG4585	Histidine kinase
XNR_RS10220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XNR_RS10225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XNR_RS10250	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XNR_RS10255	COG0193	aminoacyl-tRNA hydrolase activity
XNR_RS10265	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XNR_RS10285	COG4106	trans-aconitate 2-methyltransferase activity
XNR_RS10295	COG2197	response regulator
XNR_RS10300	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
XNR_RS10345	COG0488	(ABC) transporter
XNR_RS10350	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XNR_RS10355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XNR_RS10360	COG0084	hydrolase, TatD family'
XNR_RS10435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XNR_RS10445	COG2409	Drug exporters of the RND superfamily
XNR_RS10455	COG4946	Tricorn protease homolog
XNR_RS10455	COG0793	Belongs to the peptidase S41A family
XNR_RS10465	COG4221	oxidoreductase activity
XNR_RS10475	COG2072	flavoprotein involved in K transport
XNR_RS10485	COG0708	Exodeoxyribonuclease III
XNR_RS10495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XNR_RS10515	COG2197	response regulator
XNR_RS10555	COG0521	Mo-molybdopterin cofactor biosynthetic process
XNR_RS10555	COG0315	cyclic pyranopterin monophosphate synthase activity
XNR_RS10560	COG0315	cyclic pyranopterin monophosphate synthase activity
XNR_RS10570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XNR_RS10575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XNR_RS10585	COG3263	regulation of cellular component size
XNR_RS10600	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
XNR_RS10610	COG1970	mechanosensitive ion channel activity
XNR_RS10625	COG3191	aminopeptidase activity
XNR_RS10645	COG3384	dioxygenase
XNR_RS10650	COG1846	Transcriptional regulator
XNR_RS10705	COG2050	protein possibly involved in aromatic compounds catabolism
XNR_RS10715	COG0183	Belongs to the thiolase family
XNR_RS10720	COG1024	Enoyl-CoA hydratase
XNR_RS10725	COG1250	3-hydroxyacyl-CoA dehydrogenase
XNR_RS10730	COG3396	Phenylacetate-CoA oxygenase
XNR_RS10735	COG3460	Phenylacetate-CoA oxygenase
XNR_RS10740	COG3396	Phenylacetate-CoA oxygenase
XNR_RS10745	COG2151	metal-sulfur cluster biosynthetic enzyme
XNR_RS10750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XNR_RS10810	COG0582	viral genome integration into host DNA
XNR_RS10850	COG1609	Transcriptional regulator
XNR_RS10930	COG1278	Cold shock
XNR_RS11010	COG5297	Belongs to the glycosyl hydrolase family 6
XNR_RS11030	COG0148	phosphopyruvate hydratase activity
XNR_RS11045	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
XNR_RS11075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XNR_RS11110	COG0515	serine threonine protein kinase
XNR_RS11110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XNR_RS11115	COG1309	transcriptional regulator
XNR_RS11135	COG2072	flavoprotein involved in K transport
XNR_RS11150	COG2271	Major facilitator Superfamily
XNR_RS11170	COG1366	Belongs to the anti-sigma-factor antagonist family
XNR_RS11250	COG4821	SIS domain
XNR_RS11260	COG0259	pyridoxamine-phosphate oxidase activity
XNR_RS11280	COG1024	Enoyl-CoA hydratase
XNR_RS11295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XNR_RS11330	COG0583	DNA-binding transcription factor activity
XNR_RS11340	COG0247	lactate metabolic process
XNR_RS11340	COG0277	FAD linked oxidase domain protein
XNR_RS11345	COG2205	protein histidine kinase activity
XNR_RS11365	COG2124	cytochrome p450
XNR_RS11375	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XNR_RS11470	COG0667	Aldo Keto reductase
XNR_RS11495	COG2252	PERMEase
XNR_RS11505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
XNR_RS11530	COG2814	Major facilitator Superfamily
XNR_RS11540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XNR_RS11545	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
XNR_RS11550	COG1278	Cold shock
XNR_RS11560	COG2197	response regulator
XNR_RS11565	COG1132	(ABC) transporter
XNR_RS11570	COG1132	(ABC) transporter
XNR_RS11580	COG0515	serine threonine protein kinase
XNR_RS11585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XNR_RS11590	COG1120	ATPase activity
XNR_RS11595	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS11600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS11610	COG1295	ribonuclease BN
XNR_RS11620	COG2124	cytochrome p450
XNR_RS11675	COG1061	Type III restriction enzyme res subunit
XNR_RS11705	COG0667	Aldo Keto reductase
XNR_RS11710	COG0789	Transcriptional regulator
XNR_RS11735	COG3973	AAA domain
XNR_RS11780	COG4585	Histidine kinase
XNR_RS11785	COG2197	response regulator
XNR_RS11820	COG0406	alpha-ribazole phosphatase activity
XNR_RS11830	COG1737	Transcriptional regulator
XNR_RS11835	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
XNR_RS11840	COG1263	PTS System
XNR_RS11840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XNR_RS11845	COG0667	Aldo Keto reductase
XNR_RS11885	COG1278	Cold shock
XNR_RS11900	COG0463	Glycosyl transferase, family 2
XNR_RS11925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XNR_RS11965	COG1105	Belongs to the carbohydrate kinase PfkB family
XNR_RS11990	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XNR_RS12020	COG1309	transcriptional regulator
XNR_RS12035	COG0577	efflux transmembrane transporter activity
XNR_RS12035	COG1136	(ABC) transporter
XNR_RS12070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XNR_RS12140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XNR_RS12210	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
XNR_RS12225	COG1366	Belongs to the anti-sigma-factor antagonist family
XNR_RS12230	COG1366	Belongs to the anti-sigma-factor antagonist family
XNR_RS12235	COG2172	sigma factor antagonist activity
XNR_RS12260	COG0577	efflux transmembrane transporter activity
XNR_RS12260	COG1136	(ABC) transporter
XNR_RS12265	COG0577	efflux transmembrane transporter activity
XNR_RS12320	COG4585	Histidine kinase
XNR_RS12325	COG2197	response regulator
XNR_RS12330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XNR_RS12335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XNR_RS12355	COG0301	tRNA thio-modification
XNR_RS12385	COG0513	Belongs to the DEAD box helicase family
XNR_RS12390	COG1278	Cold shock
XNR_RS12420	COG2208	phosphoserine phosphatase activity
XNR_RS12420	COG2770	Histidine kinase
XNR_RS12455	COG0456	acetyltransferase
XNR_RS12465	COG0436	Aminotransferase
XNR_RS12475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XNR_RS12485	COG3486	L-lysine 6-monooxygenase (NADPH) activity
XNR_RS12495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XNR_RS12495	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XNR_RS12540	COG2814	Major facilitator Superfamily
XNR_RS12600	COG1196	nuclear chromosome segregation
XNR_RS12665	COG3842	ATPase activity
XNR_RS12675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XNR_RS12685	COG1253	flavin adenine dinucleotide binding
XNR_RS12700	COG0215	cysteine-tRNA ligase activity
XNR_RS12715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNR_RS12735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XNR_RS12740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XNR_RS12745	COG1329	Transcriptional regulator
XNR_RS12755	COG0745	RESPONSE REGULATOR receiver
XNR_RS12760	COG5002	protein histidine kinase activity
XNR_RS12770	COG2076	Multidrug Resistance protein
XNR_RS12795	COG3311	Transcriptional regulator
XNR_RS12845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XNR_RS12880	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XNR_RS12900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XNR_RS12905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XNR_RS12935	COG4942	peptidase
XNR_RS12940	COG0783	Belongs to the Dps family
XNR_RS12945	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XNR_RS12950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS12970	COG5001	Diguanylate cyclase
XNR_RS12985	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XNR_RS12990	COG0793	Belongs to the peptidase S41A family
XNR_RS13005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XNR_RS13010	COG1316	TRANSCRIPTIONal
XNR_RS13020	COG0640	Transcriptional regulator
XNR_RS13030	COG1252	NADH dehydrogenase
XNR_RS13060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XNR_RS13070	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
XNR_RS13080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XNR_RS13115	COG2186	Transcriptional regulator
XNR_RS13125	COG0318	PFAM AMP-dependent synthetase and ligase
XNR_RS13130	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XNR_RS13130	COG0825	malonyl-CoA metabolic process
XNR_RS13140	COG0789	Transcriptional regulator
XNR_RS13155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XNR_RS13160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XNR_RS13175	COG0789	Transcriptional regulator
XNR_RS13190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XNR_RS13205	COG2801	Transposase and inactivated derivatives
XNR_RS13210	COG2197	response regulator
XNR_RS13240	COG2249	NAD(P)H dehydrogenase (quinone) activity
XNR_RS13255	COG0537	adenosine 5'-monophosphoramidase activity
XNR_RS13295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XNR_RS13380	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XNR_RS13385	COG1754	DNA topoisomerase type I activity
XNR_RS13385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XNR_RS13395	COG2890	protein-(glutamine-N5) methyltransferase activity
XNR_RS13410	COG1366	Belongs to the anti-sigma-factor antagonist family
XNR_RS13415	COG1205	dead DEAH box helicase
XNR_RS13415	COG1111	helicase
XNR_RS13475	COG0659	secondary active sulfate transmembrane transporter activity
XNR_RS13480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XNR_RS13485	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XNR_RS13495	COG2267	carboxylic ester hydrolase activity
XNR_RS13530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XNR_RS13540	COG0251	oxidation-reduction process
XNR_RS13550	COG0003	Pfam Anion-transporting ATPase
XNR_RS13570	COG1408	metallophosphoesterase
XNR_RS13585	COG1136	(ABC) transporter
XNR_RS13585	COG0577	efflux transmembrane transporter activity
XNR_RS13600	COG2318	DinB family
XNR_RS13625	COG0596	Alpha beta hydrolase
XNR_RS13645	COG2130	NADP-dependent
XNR_RS13690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XNR_RS13695	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XNR_RS13755	COG1733	regulation of RNA biosynthetic process
XNR_RS13765	COG0666	response to abiotic stimulus
XNR_RS13780	COG2197	response regulator
XNR_RS13850	COG0596	Alpha beta hydrolase
XNR_RS13925	COG1470	cell adhesion involved in biofilm formation
XNR_RS13925	COG0366	Alpha amylase catalytic
XNR_RS13940	COG0579	oxidoreductase
XNR_RS13945	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XNR_RS13955	COG0667	Aldo Keto reductase
XNR_RS13985	COG0542	response to heat
XNR_RS14015	COG0513	Belongs to the DEAD box helicase family
XNR_RS14050	COG1643	Atp-dependent helicase
XNR_RS14085	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XNR_RS14100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XNR_RS14105	COG0047	phosphoribosylformylglycinamidine synthase activity
XNR_RS14110	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XNR_RS14145	COG2197	response regulator
XNR_RS14155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XNR_RS14170	COG0151	Belongs to the GarS family
XNR_RS14190	COG0659	secondary active sulfate transmembrane transporter activity
XNR_RS14200	COG2837	iron assimilation
XNR_RS14205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XNR_RS14280	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XNR_RS14315	COG1191	sigma factor activity
XNR_RS14320	COG1191	sigma factor activity
XNR_RS14330	COG0477	Major facilitator Superfamily
XNR_RS14350	COG0477	Major facilitator Superfamily
XNR_RS14360	COG0745	RESPONSE REGULATOR receiver
XNR_RS14395	COG0318	PFAM AMP-dependent synthetase and ligase
XNR_RS14400	COG1595	DNA-templated transcription, initiation
XNR_RS14420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XNR_RS14435	COG0653	protein targeting
XNR_RS14450	COG0006	proline dipeptidase activity
XNR_RS14470	COG1999	signal sequence binding
XNR_RS14485	COG2837	iron assimilation
XNR_RS14490	COG0077	Prephenate dehydratase
XNR_RS14495	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XNR_RS14500	COG0561	phosphatase activity
XNR_RS14520	COG1131	(ABC) transporter
XNR_RS14540	COG0561	phosphatase activity
XNR_RS14545	COG1196	nuclear chromosome segregation
XNR_RS14545	COG0739	heme binding
XNR_RS14545	COG0741	lytic transglycosylase activity
XNR_RS14555	COG4988	ABC transporter
XNR_RS14560	COG1294	oxidase, subunit
XNR_RS14565	COG1271	oxidase subunit
XNR_RS14570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XNR_RS14575	COG1609	Transcriptional regulator
XNR_RS14590	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XNR_RS14615	COG0662	Cupin 2, conserved barrel domain protein
XNR_RS14620	COG1950	PFAM Membrane protein of
XNR_RS14625	COG0626	cystathionine gamma-synthase activity
XNR_RS14670	COG0110	maltose O-acetyltransferase activity
XNR_RS14675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
XNR_RS14755	COG0305	Participates in initiation and elongation during chromosome replication
XNR_RS14765	COG0359	binds to the 23S rRNA
XNR_RS14770	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XNR_RS14775	COG0629	single-stranded DNA binding
XNR_RS14780	COG0360	Binds together with S18 to 16S ribosomal RNA
XNR_RS14805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XNR_RS14830	COG0617	tRNA 3'-terminal CCA addition
XNR_RS14845	COG2815	serine threonine protein kinase
XNR_RS14845	COG0515	serine threonine protein kinase
XNR_RS14850	COG1595	DNA-templated transcription, initiation
XNR_RS14860	COG0492	ferredoxin-NADP+ reductase activity
XNR_RS14865	COG3118	belongs to the thioredoxin family
XNR_RS14880	COG1192	Involved in chromosome partitioning
XNR_RS14885	COG0357	Ribosomal RNA small subunit methyltransferase G
XNR_RS14895	COG0706	membrane insertase activity
XNR_RS14900	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XNR_RS14910	COG0592	DNA-directed DNA polymerase activity
XNR_RS14915	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
XNR_RS14920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XNR_RS14925	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
XNR_RS14930	COG0187	DNA topoisomerase II activity
XNR_RS14935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XNR_RS14970	COG0515	serine threonine protein kinase
XNR_RS15000	COG1278	Cold shock
XNR_RS15005	COG1309	transcriptional regulator
XNR_RS15025	COG0705	Rhomboid family
XNR_RS15050	COG3764	Sortase (surface protein transpeptidase)
XNR_RS15055	COG3764	Sortase (surface protein transpeptidase)
XNR_RS15060	COG0515	serine threonine protein kinase
XNR_RS15080	COG1716	ATPase activity
XNR_RS15085	COG1716	ATPase activity
XNR_RS15095	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XNR_RS15100	COG1733	regulation of RNA biosynthetic process
XNR_RS15140	COG1522	sequence-specific DNA binding
XNR_RS15165	COG0303	'Molybdopterin
XNR_RS15170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XNR_RS15195	COG0515	serine threonine protein kinase
XNR_RS15200	COG0515	serine threonine protein kinase
XNR_RS15215	COG0022	dehydrogenase e1 component
XNR_RS15220	COG0508	dehydrogenase complex catalyzes the overall conversion of
XNR_RS15270	COG1362	aminopeptidase activity
XNR_RS15290	COG1960	acyl-CoA dehydrogenase activity
XNR_RS15300	COG1741	Belongs to the pirin family
XNR_RS15305	COG0628	permease
XNR_RS15315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XNR_RS15325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XNR_RS15365	COG1316	TRANSCRIPTIONal
XNR_RS15380	COG2268	Band 7 protein
XNR_RS15385	COG1937	Protein conserved in bacteria
XNR_RS15390	COG1064	alcohol dehydrogenase
XNR_RS15395	COG2208	phosphoserine phosphatase activity
XNR_RS15395	COG2770	Histidine kinase
XNR_RS15425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XNR_RS15445	COG0477	Major facilitator Superfamily
XNR_RS15470	COG0657	acetylesterase activity
XNR_RS15475	COG0247	lactate metabolic process
XNR_RS15475	COG2181	nitrate reductase activity
XNR_RS15480	COG1434	Gram-negative-bacterium-type cell wall biogenesis
XNR_RS15520	COG0717	Belongs to the dCTP deaminase family
XNR_RS15530	COG0326	Molecular chaperone. Has ATPase activity
XNR_RS15550	COG2814	Major facilitator Superfamily
XNR_RS15560	COG1695	Transcriptional regulator
XNR_RS15590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XNR_RS15590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XNR_RS15625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS15630	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS15635	COG1120	ATPase activity
XNR_RS15660	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
XNR_RS15680	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XNR_RS15690	COG1131	(ABC) transporter
XNR_RS15695	COG1725	Transcriptional regulator
XNR_RS15730	COG0443	Heat shock 70 kDa protein
XNR_RS15735	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XNR_RS15740	COG0484	heat shock protein binding
XNR_RS15745	COG0789	Transcriptional regulator
XNR_RS15770	COG0477	Major facilitator Superfamily
XNR_RS15785	COG2378	regulation of single-species biofilm formation
XNR_RS15840	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XNR_RS15855	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XNR_RS15860	COG0191	fructose-bisphosphate aldolase activity
XNR_RS15865	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
XNR_RS15870	COG0477	Major facilitator Superfamily
XNR_RS15890	COG3844	kynureninase activity
XNR_RS15900	COG0702	epimerase
XNR_RS15905	COG4585	Histidine kinase
XNR_RS15910	COG2197	response regulator
XNR_RS15920	COG1335	isochorismatase
XNR_RS15935	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XNR_RS15950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XNR_RS15955	COG0798	PFAM Bile acid sodium symporter
XNR_RS15975	COG2124	cytochrome p450
XNR_RS15980	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XNR_RS15985	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XNR_RS16040	COG0509	glycine decarboxylation via glycine cleavage system
XNR_RS16050	COG2318	DinB family
XNR_RS16070	COG0741	lytic transglycosylase activity
XNR_RS16070	COG1196	nuclear chromosome segregation
XNR_RS16070	COG0739	heme binding
XNR_RS16075	COG0671	phosphoesterase, PA-phosphatase related
XNR_RS16085	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS16095	COG1937	Protein conserved in bacteria
XNR_RS16105	COG0306	phosphate transporter
XNR_RS16110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XNR_RS16130	COG0494	nUDIX hydrolase
XNR_RS16130	COG0406	alpha-ribazole phosphatase activity
XNR_RS16160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
XNR_RS16165	COG2318	DinB family
XNR_RS16205	COG2770	Histidine kinase
XNR_RS16205	COG2208	phosphoserine phosphatase activity
XNR_RS16215	COG0596	Alpha beta hydrolase
XNR_RS16220	COG3903	Transcriptional regulator
XNR_RS16220	COG3629	intracellular signal transduction
XNR_RS16255	COG1595	DNA-templated transcription, initiation
XNR_RS16310	COG2267	carboxylic ester hydrolase activity
XNR_RS16345	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XNR_RS16355	COG1131	(ABC) transporter
XNR_RS16365	COG1725	Transcriptional regulator
XNR_RS16370	COG4941	Belongs to the sigma-70 factor family
XNR_RS16415	COG0456	acetyltransferase
XNR_RS16420	COG0737	Belongs to the 5'-nucleotidase family
XNR_RS16425	COG0235	Class ii aldolase
XNR_RS16430	COG2160	L-arabinose isomerase activity
XNR_RS16440	COG1609	Transcriptional regulator
XNR_RS16450	COG1129	ABC transporter
XNR_RS16455	COG4214	carbohydrate transport
XNR_RS16470	COG0745	RESPONSE REGULATOR receiver
XNR_RS16475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XNR_RS16480	COG1609	Transcriptional regulator
XNR_RS16485	COG0745	RESPONSE REGULATOR receiver
XNR_RS16510	COG2897	thiosulfate sulfurtransferase activity
XNR_RS16550	COG3485	protocatechuate 3,4-dioxygenase
XNR_RS16555	COG0735	belongs to the Fur family
XNR_RS16560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XNR_RS16565	COG1490	D-aminoacyl-tRNA deacylase activity
XNR_RS16580	COG0789	Transcriptional regulator
XNR_RS16585	COG2249	NAD(P)H dehydrogenase (quinone) activity
XNR_RS16600	COG1476	TRANSCRIPTIONal
XNR_RS16635	COG4106	trans-aconitate 2-methyltransferase activity
XNR_RS16655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XNR_RS16665	COG2226	methyltransferase
XNR_RS16685	COG1309	transcriptional regulator
XNR_RS16735	COG0457	Tetratricopeptide repeat
XNR_RS16760	COG1388	LysM domain
XNR_RS16760	COG3103	Sh3 type 3 domain protein
XNR_RS16760	COG0791	NLP P60 protein
XNR_RS16770	COG0438	transferase activity, transferring glycosyl groups
XNR_RS16795	COG0588	phosphoglycerate mutase activity
XNR_RS16810	COG0739	heme binding
XNR_RS16825	COG0477	Major facilitator Superfamily
XNR_RS16825	COG2814	Major facilitator Superfamily
XNR_RS16840	COG2159	amidohydrolase
XNR_RS16845	COG2828	Protein conserved in bacteria
XNR_RS16850	COG2186	Transcriptional regulator
XNR_RS16880	COG0501	Belongs to the peptidase M48B family
XNR_RS16885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XNR_RS16885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XNR_RS16930	COG1289	transmembrane transporter activity
XNR_RS16955	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS16960	COG2318	DinB family
XNR_RS16970	COG0655	NAD(P)H dehydrogenase (quinone) activity
XNR_RS16975	COG0789	Transcriptional regulator
XNR_RS16980	COG0586	Pfam SNARE associated Golgi protein
XNR_RS16990	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XNR_RS16995	COG2027	D-alanyl-D-alanine carboxypeptidase
XNR_RS17005	COG0037	tRNA processing
XNR_RS17020	COG0302	gtp cyclohydrolase
XNR_RS17030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XNR_RS17035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XNR_RS17050	COG1125	glycine betaine transport
XNR_RS17050	COG0517	IMP dehydrogenase activity
XNR_RS17055	COG1174	glycine betaine transport
XNR_RS17060	COG1174	glycine betaine transport
XNR_RS17065	COG1732	Glycine betaine
XNR_RS17075	COG0477	Major facilitator Superfamily
XNR_RS17090	COG0477	Major facilitator Superfamily
XNR_RS17155	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS17170	COG4585	Histidine kinase
XNR_RS17175	COG2197	response regulator
XNR_RS17195	COG0649	NAD binding
XNR_RS17210	COG2197	response regulator
XNR_RS17225	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XNR_RS17230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
XNR_RS17240	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XNR_RS17255	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
XNR_RS17280	COG0739	heme binding
XNR_RS17285	COG2205	protein histidine kinase activity
XNR_RS17290	COG0745	RESPONSE REGULATOR receiver
XNR_RS17300	COG1595	DNA-templated transcription, initiation
XNR_RS17310	COG0671	phosphoesterase, PA-phosphatase related
XNR_RS17320	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
XNR_RS17355	COG0248	Ppx GppA phosphatase
XNR_RS17365	COG1082	Xylose isomerase domain protein TIM barrel
XNR_RS17370	COG1309	transcriptional regulator
XNR_RS17375	COG0129	dihydroxy-acid dehydratase activity
XNR_RS17385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XNR_RS17405	COG1129	ABC transporter
XNR_RS17405	COG0842	Transport permease protein
XNR_RS17415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
XNR_RS17420	COG0180	Tryptophanyl-tRNA synthetase
XNR_RS17445	COG2223	nitrite transmembrane transporter activity
XNR_RS17450	COG0123	including yeast histone deacetylase and acetoin utilization protein
XNR_RS17475	COG4552	Acetyltransferase involved in intracellular survival and related
XNR_RS17500	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
XNR_RS17505	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XNR_RS17510	COG0181	hydroxymethylbilane synthase activity
XNR_RS17515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XNR_RS17515	COG1648	precorrin-2 dehydrogenase activity
XNR_RS17520	COG0113	porphobilinogen synthase activity
XNR_RS17540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XNR_RS17545	COG0018	arginyl-trna synthetase
XNR_RS17550	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
XNR_RS17575	COG1690	Belongs to the RtcB family
XNR_RS17580	COG0659	secondary active sulfate transmembrane transporter activity
XNR_RS17625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XNR_RS17630	COG0406	alpha-ribazole phosphatase activity
XNR_RS17640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XNR_RS17645	COG0785	Cytochrome C biogenesis protein
XNR_RS17655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XNR_RS17670	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
XNR_RS17675	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XNR_RS17680	COG0163	prenyltransferase activity
XNR_RS17690	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
XNR_RS17705	COG1301	dicarboxylic acid transport
XNR_RS17720	COG1131	(ABC) transporter
XNR_RS17725	COG3559	Exporter of polyketide antibiotics
XNR_RS17755	COG0183	Belongs to the thiolase family
XNR_RS17765	COG1278	Cold shock
XNR_RS17770	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
XNR_RS17890	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
XNR_RS17950	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
XNR_RS17960	COG2226	methyltransferase
XNR_RS17985	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNR_RS17990	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNR_RS17995	COG0649	NAD binding
XNR_RS18005	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XNR_RS18010	COG1034	ATP synthesis coupled electron transport
XNR_RS18015	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XNR_RS18020	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNR_RS18025	COG0839	Belongs to the complex I subunit 6 family
XNR_RS18030	COG0713	ATP synthesis coupled electron transport
XNR_RS18035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XNR_RS18045	COG1007	ATP synthesis coupled electron transport
XNR_RS18050	COG0514	ATP-dependent DNA helicase (RecQ)
XNR_RS18070	COG0561	phosphatase activity
XNR_RS18080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XNR_RS18095	COG3104	oligopeptide transport
XNR_RS18100	COG0142	geranyltranstransferase activity
XNR_RS18165	COG0488	(ABC) transporter
XNR_RS18175	COG0702	epimerase
XNR_RS18180	COG1733	regulation of RNA biosynthetic process
XNR_RS18185	COG1013	pyruvate-flavodoxin oxidoreductase activity
XNR_RS18190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
XNR_RS18190	COG0674	pyruvate-flavodoxin oxidoreductase activity
XNR_RS18195	COG2197	response regulator
XNR_RS18200	COG4585	Histidine kinase
XNR_RS18210	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNR_RS18215	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNR_RS18220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNR_RS18225	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XNR_RS18230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XNR_RS18235	COG0839	Belongs to the complex I subunit 6 family
XNR_RS18240	COG0713	ATP synthesis coupled electron transport
XNR_RS18245	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XNR_RS18255	COG1007	ATP synthesis coupled electron transport
XNR_RS18260	COG0501	Belongs to the peptidase M48B family
XNR_RS18265	COG3304	Inner membrane component domain
XNR_RS18270	COG2261	transglycosylase associated protein
XNR_RS18275	COG1666	GTP binding
XNR_RS18290	COG0702	epimerase
XNR_RS18295	COG0402	S-adenosylhomocysteine deaminase activity
XNR_RS18310	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XNR_RS18315	COG2030	dehydratase
XNR_RS18325	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XNR_RS18335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XNR_RS18340	COG0436	Aminotransferase
XNR_RS18365	COG0081	regulation of translation
XNR_RS18375	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XNR_RS18380	COG0222	ribosome binding
XNR_RS18385	COG0085	RNA polymerase activity
XNR_RS18390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XNR_RS18425	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XNR_RS18430	COG0049	tRNA binding
XNR_RS18435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XNR_RS18455	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XNR_RS18470	COG0051	transcription antitermination factor activity, RNA binding
XNR_RS18475	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XNR_RS18480	COG0088	Forms part of the polypeptide exit tunnel
XNR_RS18485	COG0089	rRNA binding
XNR_RS18490	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XNR_RS18495	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XNR_RS18500	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XNR_RS18505	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XNR_RS18510	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XNR_RS18515	COG0255	Belongs to the universal ribosomal protein uL29 family
XNR_RS18520	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XNR_RS18525	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XNR_RS18530	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XNR_RS18535	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XNR_RS18540	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XNR_RS18545	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XNR_RS18550	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XNR_RS18555	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XNR_RS18560	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XNR_RS18565	COG1841	ribosomal large subunit assembly
XNR_RS18570	COG0200	Binds to the 23S rRNA
XNR_RS18575	COG0201	protein transport
XNR_RS18580	COG0563	adenylate kinase activity
XNR_RS18590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XNR_RS18595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XNR_RS18600	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XNR_RS18605	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XNR_RS18615	COG0203	ribosomal protein L17
XNR_RS18620	COG0101	tRNA pseudouridine synthase activity
XNR_RS18630	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XNR_RS18635	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XNR_RS18640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XNR_RS18645	COG1072	(Pantothenic acid kinase))
XNR_RS18660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XNR_RS18675	COG4977	sequence-specific DNA binding
XNR_RS18690	COG0736	holo-[acyl-carrier-protein] synthase activity
XNR_RS18750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XNR_RS18755	COG2267	carboxylic ester hydrolase activity
XNR_RS18760	COG0802	atpase or kinase
XNR_RS18785	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XNR_RS18820	COG0726	polysaccharide deacetylase
XNR_RS18835	COG4221	oxidoreductase activity
XNR_RS18840	COG0583	DNA-binding transcription factor activity
XNR_RS18850	COG2197	response regulator
XNR_RS18855	COG1595	DNA-templated transcription, initiation
XNR_RS18865	COG0516	GMP reductase activity
XNR_RS18875	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
XNR_RS18910	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS18930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XNR_RS18930	COG0519	Catalyzes the synthesis of GMP from XMP
XNR_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS18980	COG2197	response regulator
XNR_RS18985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XNR_RS19030	COG1846	Transcriptional regulator
XNR_RS19030	COG0456	acetyltransferase
XNR_RS19040	COG1228	amidohydrolase
XNR_RS19060	COG0791	NLP P60 protein
XNR_RS19100	COG2066	Belongs to the glutaminase family
XNR_RS19105	COG0739	heme binding
XNR_RS19105	COG1196	nuclear chromosome segregation
XNR_RS19105	COG0741	lytic transglycosylase activity
XNR_RS19110	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
XNR_RS19115	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XNR_RS19115	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XNR_RS19130	COG0714	Associated with various cellular activities
XNR_RS19135	COG2425	protein containing a von Willebrand factor type A (vWA) domain
XNR_RS19140	COG3552	Protein containing von Willebrand factor type A (VWA) domain
XNR_RS19145	COG0045	succinate-CoA ligase (ADP-forming) activity
XNR_RS19175	COG0138	bifunctional purine biosynthesis protein purh
XNR_RS19185	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XNR_RS19210	COG0039	L-malate dehydrogenase activity
XNR_RS19230	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS19240	COG4175	Glycine betaine
XNR_RS19240	COG0517	IMP dehydrogenase activity
XNR_RS19270	COG0395	ABC-type sugar transport system, permease component
XNR_RS19275	COG1175	transmembrane transport
XNR_RS19295	COG2362	D-Aminopeptidase
XNR_RS19300	COG1609	Transcriptional regulator
XNR_RS19310	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XNR_RS19315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XNR_RS19325	COG0754	glutathionylspermidine amidase activity
XNR_RS19335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XNR_RS19370	COG0180	Tryptophanyl-tRNA synthetase
XNR_RS19410	COG1295	ribonuclease BN
XNR_RS19425	COG1408	metallophosphoesterase
XNR_RS19465	COG1309	transcriptional regulator
XNR_RS19480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XNR_RS19485	COG1053	succinate dehydrogenase
XNR_RS19495	COG2009	succinate dehydrogenase
XNR_RS19535	COG1215	transferase activity, transferring glycosyl groups
XNR_RS19540	COG1595	DNA-templated transcription, initiation
XNR_RS19610	COG1216	Glycosyl transferase, family 2
XNR_RS19620	COG1083	cytidylyl-transferase
XNR_RS19625	COG2089	acid synthase
XNR_RS19635	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
XNR_RS19635	COG1473	amidohydrolase
XNR_RS19680	COG1744	ABC transporter substrate-binding protein PnrA-like
XNR_RS19685	COG3845	ABC transporter
XNR_RS19690	COG4603	Belongs to the binding-protein-dependent transport system permease family
XNR_RS19695	COG1079	Belongs to the binding-protein-dependent transport system permease family
XNR_RS19735	COG2814	Major facilitator Superfamily
XNR_RS19740	COG0583	DNA-binding transcription factor activity
XNR_RS19765	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XNR_RS19790	COG2205	protein histidine kinase activity
XNR_RS19795	COG0745	RESPONSE REGULATOR receiver
XNR_RS19800	COG1595	DNA-templated transcription, initiation
XNR_RS19845	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS19865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XNR_RS19900	COG4770	biotin carboxylase activity
XNR_RS19910	COG0424	maF-like protein
XNR_RS19920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XNR_RS19930	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
XNR_RS19935	COG1024	Enoyl-CoA hydratase
XNR_RS19945	COG2986	histidine ammonia-lyase
XNR_RS19965	COG1136	(ABC) transporter
XNR_RS19970	COG1064	alcohol dehydrogenase
XNR_RS19975	COG2318	DinB family
XNR_RS20000	COG2255	four-way junction helicase activity
XNR_RS20005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XNR_RS20020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XNR_RS20030	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
XNR_RS20065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XNR_RS20085	COG1331	Highly conserved protein containing a thioredoxin domain
XNR_RS20105	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
XNR_RS20135	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
XNR_RS20150	COG1414	Transcriptional regulator
XNR_RS20155	COG0251	oxidation-reduction process
XNR_RS20240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XNR_RS20275	COG2894	cell division
XNR_RS20305	COG2197	response regulator
XNR_RS20330	COG2814	Major facilitator Superfamily
XNR_RS20335	COG0656	L-ascorbic acid biosynthetic process
XNR_RS20340	COG2304	oxidoreductase activity
XNR_RS20350	COG3548	integral membrane protein
XNR_RS20365	COG0667	Aldo Keto reductase
XNR_RS20370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XNR_RS20375	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XNR_RS20395	COG0450	alkyl hydroperoxide reductase
XNR_RS20400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XNR_RS20410	COG1136	(ABC) transporter
XNR_RS20430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XNR_RS20445	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XNR_RS20455	COG0114	fumarate hydratase activity
XNR_RS20465	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
XNR_RS20465	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
XNR_RS20475	COG0515	serine threonine protein kinase
XNR_RS20500	COG0778	Nitroreductase
XNR_RS20505	COG1722	exodeoxyribonuclease VII activity
XNR_RS20510	COG1570	exodeoxyribonuclease VII activity
XNR_RS20515	COG0531	amino acid
XNR_RS20520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XNR_RS20535	COG0012	GTP binding
XNR_RS20565	COG0709	Synthesizes selenophosphate from selenide and ATP
XNR_RS20595	COG0406	alpha-ribazole phosphatase activity
XNR_RS20620	COG0745	RESPONSE REGULATOR receiver
XNR_RS20685	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XNR_RS20690	COG4977	sequence-specific DNA binding
XNR_RS20705	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XNR_RS20730	COG3486	L-lysine 6-monooxygenase (NADPH) activity
XNR_RS20760	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS20770	COG3655	Transcriptional regulator
XNR_RS20830	COG1960	acyl-CoA dehydrogenase activity
XNR_RS20845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
XNR_RS20850	COG1309	transcriptional regulator
XNR_RS20860	COG1946	Acyl-CoA thioesterase
XNR_RS20900	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XNR_RS20910	COG3960	tartronate-semialdehyde synthase activity
XNR_RS20930	COG1472	Belongs to the glycosyl hydrolase 3 family
XNR_RS20935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XNR_RS20980	COG3718	enzyme involved in inositol metabolism
XNR_RS20985	COG3962	Belongs to the TPP enzyme family
XNR_RS21000	COG1131	(ABC) transporter
XNR_RS21030	COG3903	Transcriptional regulator
XNR_RS21030	COG3629	intracellular signal transduction
XNR_RS21105	COG0629	single-stranded DNA binding
XNR_RS21140	COG1136	(ABC) transporter
XNR_RS21160	COG0667	Aldo Keto reductase
XNR_RS21165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XNR_RS21200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XNR_RS21225	COG1486	melibiose metabolic process
XNR_RS21235	COG0668	transmembrane transport
XNR_RS21250	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XNR_RS21270	COG0583	DNA-binding transcription factor activity
XNR_RS21300	COG4266	Belongs to the allantoicase family
XNR_RS21335	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XNR_RS21340	COG0076	glutamate decarboxylase activity
XNR_RS21345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XNR_RS21350	COG1113	amino acid transport
XNR_RS21355	COG1113	amino acid transport
XNR_RS21360	COG1268	BioY protein
XNR_RS21365	COG1113	amino acid transport
XNR_RS21395	COG0475	glutathione-regulated potassium exporter activity
XNR_RS21400	COG3594	Acyltransferase
XNR_RS21420	COG0544	peptidyl-prolyl cis-trans isomerase activity
XNR_RS21425	COG0740	serine-type endopeptidase activity
XNR_RS21430	COG0740	serine-type endopeptidase activity
XNR_RS21435	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XNR_RS21445	COG0525	valine-tRNA ligase activity
XNR_RS21450	COG0285	dihydrofolate synthase activity
XNR_RS21460	COG0105	UTP biosynthetic process
XNR_RS21465	COG1077	Cell shape determining protein MreB Mrl
XNR_RS21485	COG0772	Belongs to the SEDS family
XNR_RS21510	COG1530	ribonuclease E activity
XNR_RS21515	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XNR_RS21520	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XNR_RS21525	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XNR_RS21545	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XNR_RS21555	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XNR_RS21570	COG0501	Belongs to the peptidase M48B family
XNR_RS21580	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XNR_RS21590	COG0799	negative regulation of ribosome biogenesis
XNR_RS21595	COG0588	phosphoglycerate mutase activity
XNR_RS21620	COG0495	leucyl-tRNA aminoacylation
XNR_RS21630	COG1307	EDD domain protein, DegV family
XNR_RS21635	COG1555	photosystem II stabilization
XNR_RS21650	COG2353	YceI-like domain
XNR_RS21665	COG0268	Binds directly to 16S ribosomal RNA
XNR_RS21670	COG0481	GTPase activity
XNR_RS21705	COG0484	heat shock protein binding
XNR_RS21720	COG4946	Tricorn protease homolog
XNR_RS21720	COG0793	Belongs to the peptidase S41A family
XNR_RS21725	COG0537	adenosine 5'-monophosphoramidase activity
XNR_RS21730	COG1234	tRNA 3'-trailer cleavage
XNR_RS21750	COG2515	1-aminocyclopropane-1-carboxylate deaminase
XNR_RS21755	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XNR_RS21780	COG1486	melibiose metabolic process
XNR_RS21785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XNR_RS21805	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XNR_RS21815	COG2315	Protein conserved in bacteria
XNR_RS21825	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XNR_RS21840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XNR_RS21855	COG1381	Involved in DNA repair and RecF pathway recombination
XNR_RS21860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XNR_RS21870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XNR_RS21875	COG1121	(ABC) transporter
XNR_RS21885	COG0423	glycine-tRNA ligase activity
XNR_RS21955	COG0189	ligase activity
XNR_RS21965	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XNR_RS21980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XNR_RS21985	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
XNR_RS21995	COG3467	pyridoxamine 5'-phosphate
XNR_RS22020	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
XNR_RS22025	COG1846	Transcriptional regulator
XNR_RS22025	COG1940	carbohydrate kinase activity
XNR_RS22035	COG0574	Belongs to the PEP-utilizing enzyme family
XNR_RS22035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XNR_RS22050	COG1324	tolerance protein
XNR_RS22060	COG0829	nickel cation binding
XNR_RS22065	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XNR_RS22070	COG0830	nickel cation binding
XNR_RS22075	COG0804	urea catabolic process
XNR_RS22080	COG0832	Belongs to the urease beta subunit family
XNR_RS22090	COG0738	Major facilitator superfamily
XNR_RS22095	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS22110	COG2226	methyltransferase
XNR_RS22150	COG1070	Carbohydrate kinase
XNR_RS22170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XNR_RS22175	COG0358	DNA primase activity
XNR_RS22185	COG3290	protein histidine kinase activity
XNR_RS22190	COG4565	transcriptional regulatory protein
XNR_RS22195	COG2851	Citrate transporter
XNR_RS22205	COG0232	Belongs to the dGTPase family. Type 2 subfamily
XNR_RS22225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNR_RS22250	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS22265	COG2890	protein-(glutamine-N5) methyltransferase activity
XNR_RS22280	COG1077	Cell shape determining protein MreB Mrl
XNR_RS22305	COG2130	NADP-dependent
XNR_RS22310	COG1764	response to oxidative stress
XNR_RS22340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XNR_RS22345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XNR_RS22350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XNR_RS22365	COG1741	Belongs to the pirin family
XNR_RS22385	COG0789	Transcriptional regulator
XNR_RS22390	COG0667	Aldo Keto reductase
XNR_RS22405	COG2197	response regulator
XNR_RS22410	COG4585	Histidine kinase
XNR_RS22430	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XNR_RS22475	COG1358	cellular component organization or biogenesis
XNR_RS22490	COG0586	Pfam SNARE associated Golgi protein
XNR_RS22595	COG3845	ABC transporter
XNR_RS22610	COG1657	PFAM Prenyltransferase squalene oxidase
XNR_RS22615	COG0438	transferase activity, transferring glycosyl groups
XNR_RS22645	COG0477	Major facilitator Superfamily
XNR_RS22650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XNR_RS22655	COG1960	acyl-CoA dehydrogenase activity
XNR_RS22670	COG2197	response regulator
XNR_RS22675	COG0346	lactoylglutathione lyase activity
XNR_RS22680	COG4585	Histidine kinase
XNR_RS22690	COG1131	(ABC) transporter
XNR_RS22710	COG0800	Aldolase
XNR_RS22715	COG3022	response to hydroperoxide
XNR_RS22750	COG1733	regulation of RNA biosynthetic process
XNR_RS22770	COG2226	methyltransferase
XNR_RS22775	COG0384	phenazine biosynthesis protein PhzF
XNR_RS22795	COG0076	glutamate decarboxylase activity
XNR_RS22805	COG2814	Major facilitator Superfamily
XNR_RS22810	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XNR_RS22820	COG1834	amidinotransferase
XNR_RS22840	COG1120	ATPase activity
XNR_RS22845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS22850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XNR_RS22895	COG1994	Peptidase M50
XNR_RS22900	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XNR_RS22915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XNR_RS22915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XNR_RS22920	COG2132	Multicopper oxidase
XNR_RS22940	COG0174	glutamine synthetase
XNR_RS22960	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XNR_RS22975	COG0531	amino acid
XNR_RS22980	COG1228	amidohydrolase
XNR_RS22995	COG1609	Transcriptional regulator
XNR_RS23000	COG2182	Extracellular solute-binding protein
XNR_RS23005	COG1175	transmembrane transport
XNR_RS23010	COG0395	ABC-type sugar transport system, permease component
XNR_RS23015	COG0366	Alpha amylase catalytic
XNR_RS23040	COG1309	transcriptional regulator
XNR_RS23060	COG0745	RESPONSE REGULATOR receiver
XNR_RS23090	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS23155	COG2326	polyphosphate kinase activity
XNR_RS23165	COG2376	Dihydroxyacetone kinase
XNR_RS23175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XNR_RS23215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XNR_RS23220	COG0321	lipoyl(octanoyl) transferase activity
XNR_RS23230	COG0456	acetyltransferase
XNR_RS23255	COG4221	oxidoreductase activity
XNR_RS23270	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XNR_RS23280	COG0508	dehydrogenase complex catalyzes the overall conversion of
XNR_RS23285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XNR_RS23290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XNR_RS23295	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
XNR_RS23305	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XNR_RS23350	COG2197	response regulator
XNR_RS23355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XNR_RS23360	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
XNR_RS23385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XNR_RS23390	COG1104	cysteine desulfurase activity
XNR_RS23395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XNR_RS23400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XNR_RS23410	COG1376	ErfK ybiS ycfS ynhG family protein
XNR_RS23420	COG1845	cytochrome c oxidase, subunit III
XNR_RS23425	COG2010	Cytochrome c
XNR_RS23430	COG0723	plastoquinol--plastocyanin reductase activity
XNR_RS23435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XNR_RS23440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XNR_RS23445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XNR_RS23450	COG1929	Belongs to the glycerate kinase type-1 family
XNR_RS23460	COG0745	RESPONSE REGULATOR receiver
XNR_RS23465	COG5002	protein histidine kinase activity
XNR_RS23480	COG0705	Rhomboid family
XNR_RS23515	COG0438	transferase activity, transferring glycosyl groups
XNR_RS23535	COG0003	Pfam Anion-transporting ATPase
XNR_RS23545	COG1940	carbohydrate kinase activity
XNR_RS23570	COG4585	Histidine kinase
XNR_RS23575	COG2197	response regulator
XNR_RS23580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XNR_RS23590	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
XNR_RS23595	COG0243	molybdopterin cofactor binding
XNR_RS23600	COG2193	ferroxidase activity
XNR_RS23605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XNR_RS23610	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
XNR_RS23615	COG2815	serine threonine protein kinase
XNR_RS23615	COG0515	serine threonine protein kinase
XNR_RS23620	COG2022	thiamine diphosphate biosynthetic process
XNR_RS23630	COG2022	thiamine diphosphate biosynthetic process
XNR_RS23630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XNR_RS23635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XNR_RS23645	COG0352	thiamine-phosphate diphosphorylase activity
XNR_RS23665	COG1309	transcriptional regulator
XNR_RS23675	COG1121	(ABC) transporter
XNR_RS23680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XNR_RS23700	COG0714	Associated with various cellular activities
XNR_RS23710	COG0275	rRNA processing
XNR_RS23725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XNR_RS23735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XNR_RS23740	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XNR_RS23750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XNR_RS23755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XNR_RS23760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XNR_RS23765	COG1496	oxidoreductase activity
XNR_RS23775	COG1799	cell septum assembly
XNR_RS23785	COG3599	regulation of cell shape
XNR_RS23790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XNR_RS23800	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XNR_RS23810	COG2153	protein acetylation
XNR_RS23825	COG0515	serine threonine protein kinase
XNR_RS23845	COG0587	DNA-directed DNA polymerase activity
XNR_RS23850	COG1432	Conserved Protein
XNR_RS23870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XNR_RS23890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XNR_RS23895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XNR_RS23900	COG0131	Imidazoleglycerol-phosphate dehydratase
XNR_RS23910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XNR_RS23915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XNR_RS23920	COG0251	oxidation-reduction process
XNR_RS23925	COG0107	imidazoleglycerol-phosphate synthase activity
XNR_RS23930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XNR_RS23940	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XNR_RS23970	COG0134	indole-3-glycerol-phosphate synthase activity
XNR_RS23975	COG0133	tryptophan synthase activity
XNR_RS23980	COG0159	tryptophan synthase activity
XNR_RS23990	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XNR_RS24000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XNR_RS24005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XNR_RS24035	COG0067	glutamate synthase
XNR_RS24035	COG0069	glutamate synthase activity
XNR_RS24035	COG0070	glutamate synthase
XNR_RS24050	COG1278	Cold shock
XNR_RS24055	COG0513	Belongs to the DEAD box helicase family
XNR_RS24065	COG0287	Prephenate dehydrogenase
XNR_RS24065	COG1605	Chorismate mutase
XNR_RS24095	COG3486	L-lysine 6-monooxygenase (NADPH) activity
XNR_RS24100	COG0737	Belongs to the 5'-nucleotidase family
XNR_RS24140	COG0559	Belongs to the binding-protein-dependent transport system permease family
XNR_RS24150	COG2746	aminoglycoside 3-N-acetyltransferase activity
XNR_RS24155	COG2050	protein possibly involved in aromatic compounds catabolism
XNR_RS24175	COG1643	Atp-dependent helicase
XNR_RS24180	COG2226	methyltransferase
XNR_RS24200	COG0237	dephospho-CoA kinase activity
XNR_RS24225	COG1288	antiporter activity
XNR_RS24275	COG0477	Major facilitator Superfamily
XNR_RS24285	COG0584	glycerophosphoryl diester phosphodiesterase
XNR_RS24295	COG0556	nucleotide-excision repair
XNR_RS24315	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XNR_RS24320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XNR_RS24330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XNR_RS24345	COG0322	excinuclease ABC activity
XNR_RS24350	COG1660	Displays ATPase and GTPase activities
XNR_RS24360	COG1481	regulation of sporulation
XNR_RS24365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XNR_RS24370	COG0126	phosphoglycerate kinase activity
XNR_RS24375	COG0149	triose-phosphate isomerase activity
XNR_RS24380	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XNR_RS24390	COG0166	Belongs to the GPI family
XNR_RS24395	COG0363	glucosamine-6-phosphate deaminase activity
XNR_RS24410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XNR_RS24415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XNR_RS24420	COG0109	protoheme IX farnesyltransferase activity
XNR_RS24445	COG1131	(ABC) transporter
XNR_RS24460	COG0719	Fe-S assembly protein
XNR_RS24470	COG0396	ATPase activity
XNR_RS24475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XNR_RS24480	COG0822	iron-sulfur transferase activity
XNR_RS24490	COG2171	N-acyltransferase activity
XNR_RS24520	COG2197	response regulator
XNR_RS24525	COG4585	Histidine kinase
XNR_RS24555	COG1902	pentaerythritol trinitrate reductase activity
XNR_RS24560	COG5285	phytanoyl-CoA dioxygenase
XNR_RS24565	COG1917	Cupin 2, conserved barrel domain protein
XNR_RS24575	COG0456	acetyltransferase
XNR_RS24580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XNR_RS24610	COG1797	cobyrinic acid a,c-diamide synthase activity
XNR_RS24625	COG1492	cobalamin metabolic process
XNR_RS24645	COG0235	Class ii aldolase
XNR_RS24665	COG0488	(ABC) transporter
XNR_RS24720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XNR_RS24740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
XNR_RS24755	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XNR_RS24760	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XNR_RS24770	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
XNR_RS24790	COG2261	transglycosylase associated protein
XNR_RS24795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XNR_RS24805	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XNR_RS24815	COG2186	Transcriptional regulator
XNR_RS24820	COG2807	transmembrane transport
XNR_RS24835	COG0560	Phosphoserine phosphatase
XNR_RS24835	COG3830	Belongs to the UPF0237 family
XNR_RS24840	COG1131	(ABC) transporter
XNR_RS24840	COG1716	ATPase activity
XNR_RS24840	COG0842	Transport permease protein
XNR_RS24850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XNR_RS24865	COG2197	response regulator
XNR_RS24880	COG1119	ATPase activity
XNR_RS24900	COG1881	PFAM PEBP family protein
XNR_RS24910	COG2094	Belongs to the DNA glycosylase MPG family
XNR_RS24945	COG0647	UMP catabolic process
XNR_RS24965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XNR_RS24970	COG0497	DNA recombination
XNR_RS24985	COG0297	glycogen (starch) synthase activity
XNR_RS24990	COG3896	Chloramphenicol phosphotransferase-like protein
XNR_RS25000	COG3387	PFAM Glycoside hydrolase 15-related
XNR_RS25005	COG0504	CTP synthase activity
XNR_RS25010	COG0494	nUDIX hydrolase
XNR_RS25020	COG0686	Belongs to the AlaDH PNT family
XNR_RS25035	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
XNR_RS25040	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XNR_RS25045	COG1187	pseudouridine synthase activity
XNR_RS25055	COG1397	ADP-ribosylglycohydrolase
XNR_RS25060	COG3541	Predicted nucleotidyltransferase
XNR_RS25075	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XNR_RS25085	COG1160	GTP binding
XNR_RS25105	COG0438	transferase activity, transferring glycosyl groups
XNR_RS25125	COG0671	phosphoesterase, PA-phosphatase related
XNR_RS25135	COG0477	Major facilitator Superfamily
XNR_RS25140	COG1799	cell septum assembly
XNR_RS25155	COG0765	amino acid transport
XNR_RS25165	COG0765	amino acid transport
XNR_RS25175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XNR_RS25180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNR_RS25200	COG0330	HflC and HflK could
XNR_RS25215	COG0587	DNA-directed DNA polymerase activity
XNR_RS25220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XNR_RS25285	COG1216	Glycosyl transferase, family 2
XNR_RS25305	COG2755	lipolytic protein G-D-S-L family
XNR_RS25325	COG3973	AAA domain
XNR_RS25330	COG2188	Transcriptional regulator
XNR_RS25335	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
XNR_RS25360	COG1309	transcriptional regulator
XNR_RS25405	COG3876	Protein conserved in bacteria
XNR_RS25415	COG0488	(ABC) transporter
XNR_RS25430	COG0318	PFAM AMP-dependent synthetase and ligase
XNR_RS25440	COG1960	acyl-CoA dehydrogenase activity
XNR_RS25460	COG2149	membrane
XNR_RS25465	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
XNR_RS25505	COG3265	gluconokinase activity
XNR_RS25515	COG3012	SEC-C Motif Domain Protein
XNR_RS25520	COG3189	MarR family transcriptional regulator
XNR_RS25530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XNR_RS25560	COG0667	Aldo Keto reductase
XNR_RS25565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNR_RS25575	COG0598	Magnesium transport protein CorA
XNR_RS25595	COG0215	cysteine-tRNA ligase activity
XNR_RS25610	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
XNR_RS25615	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XNR_RS25630	COG0646	methionine synthase
XNR_RS25630	COG1410	methionine synthase
XNR_RS25640	COG0747	negative chemotaxis
XNR_RS25645	COG2197	response regulator
XNR_RS25655	COG1994	Peptidase M50
XNR_RS25655	COG0517	IMP dehydrogenase activity
XNR_RS25675	COG1222	aaa ATPase
XNR_RS25680	COG4122	O-methyltransferase activity
XNR_RS25690	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
XNR_RS25695	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
XNR_RS25710	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
XNR_RS25745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XNR_RS25750	COG0805	protein transport
XNR_RS25765	COG2124	cytochrome p450
XNR_RS25795	COG0564	pseudouridine synthase activity
XNR_RS25805	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
XNR_RS25815	COG1595	DNA-templated transcription, initiation
XNR_RS25825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XNR_RS25830	COG0517	IMP dehydrogenase activity
XNR_RS25830	COG4175	Glycine betaine
XNR_RS25855	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
XNR_RS25860	COG0531	amino acid
XNR_RS25865	COG2186	Transcriptional regulator
XNR_RS25870	COG0174	glutamine synthetase
XNR_RS25875	COG1012	belongs to the aldehyde dehydrogenase family
XNR_RS25910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XNR_RS25920	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XNR_RS25925	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XNR_RS25930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XNR_RS25935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XNR_RS25945	COG5002	protein histidine kinase activity
XNR_RS25950	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XNR_RS25955	COG0072	phenylalanine-tRNA ligase activity
XNR_RS25955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XNR_RS25985	COG0697	spore germination
XNR_RS25990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XNR_RS26010	COG0477	Major facilitator Superfamily
XNR_RS26030	COG2838	Isocitrate dehydrogenase
XNR_RS26045	COG1309	transcriptional regulator
XNR_RS26060	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XNR_RS26095	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XNR_RS26100	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
XNR_RS26105	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XNR_RS26110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XNR_RS26115	COG1438	arginine binding
XNR_RS26120	COG4585	Histidine kinase
XNR_RS26125	COG2197	response regulator
XNR_RS26135	COG2409	Drug exporters of the RND superfamily
XNR_RS26140	COG0385	Bile acid
XNR_RS26150	COG0165	Argininosuccinate lyase
XNR_RS26175	COG0477	Major facilitator Superfamily
XNR_RS26180	COG0204	Acyl-transferase
XNR_RS26180	COG0318	PFAM AMP-dependent synthetase and ligase
XNR_RS26185	COG0584	glycerophosphoryl diester phosphodiesterase
XNR_RS26210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XNR_RS26215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XNR_RS26220	COG2011	ABC-type metal ion transport system permease component
XNR_RS26225	COG1464	Belongs to the NlpA lipoprotein family
XNR_RS26230	COG1464	Belongs to the NlpA lipoprotein family
XNR_RS26245	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XNR_RS26250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XNR_RS26250	COG1648	precorrin-2 dehydrogenase activity
XNR_RS26315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XNR_RS26325	COG0456	acetyltransferase
XNR_RS26380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XNR_RS26385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XNR_RS26400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XNR_RS26405	COG1560	Kdo2-lipid A biosynthetic process
XNR_RS26410	COG0438	transferase activity, transferring glycosyl groups
XNR_RS26420	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
XNR_RS26425	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
XNR_RS26430	COG0217	transcriptional regulatory protein
XNR_RS26435	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XNR_RS26440	COG0632	four-way junction helicase activity
XNR_RS26445	COG2255	four-way junction helicase activity
XNR_RS26455	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XNR_RS26460	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XNR_RS26465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XNR_RS26470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XNR_RS26480	COG1196	nuclear chromosome segregation
XNR_RS26485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XNR_RS26495	COG0124	histidyl-tRNA synthetase
XNR_RS26510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XNR_RS26525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XNR_RS26530	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XNR_RS26535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XNR_RS26540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XNR_RS26545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XNR_RS26550	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XNR_RS26555	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XNR_RS26565	COG0006	proline dipeptidase activity
XNR_RS26570	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XNR_RS26575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XNR_RS26585	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
XNR_RS26590	COG0540	Belongs to the ATCase OTCase family
XNR_RS26595	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XNR_RS26605	COG0505	Belongs to the CarA family
XNR_RS26610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XNR_RS26615	COG0167	dihydroorotate dehydrogenase activity
XNR_RS26620	COG0284	orotidine-5'-phosphate decarboxylase activity
XNR_RS26635	COG1758	RNA polymerase activity
XNR_RS26645	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XNR_RS26680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XNR_RS26695	COG2318	DinB family
XNR_RS26700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
XNR_RS26705	COG2390	Transcriptional regulator
XNR_RS26745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XNR_RS26765	COG0697	spore germination
XNR_RS26770	COG2233	PERMEase
XNR_RS26780	COG0738	Major facilitator superfamily
XNR_RS26785	COG1940	carbohydrate kinase activity
XNR_RS26785	COG1846	Transcriptional regulator
XNR_RS26790	COG1090	epimerase
XNR_RS26805	COG3201	nicotinamide mononucleotide transporter
XNR_RS26810	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XNR_RS26810	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XNR_RS26815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XNR_RS26820	COG0140	phosphoribosyl-ATP diphosphatase activity
XNR_RS26825	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XNR_RS26855	COG1960	acyl-CoA dehydrogenase activity
XNR_RS26875	COG0463	Glycosyl transferase, family 2
XNR_RS26880	COG3030	protein affecting phage T7 exclusion by the F plasmid
XNR_RS26890	COG2270	Major facilitator Superfamily
XNR_RS26900	COG2364	Membrane
XNR_RS26905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XNR_RS26995	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
XNR_RS27015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XNR_RS27025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XNR_RS27055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XNR_RS27075	COG1716	ATPase activity
XNR_RS27095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XNR_RS27105	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XNR_RS27105	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XNR_RS27145	COG0539	negative regulation of cytoplasmic translation
XNR_RS27165	COG0697	spore germination
XNR_RS27180	COG0697	spore germination
XNR_RS27200	COG4251	negative regulation of phosphorylation
XNR_RS27210	COG0154	amidase activity
XNR_RS27250	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XNR_RS27280	COG0815	Transfers the fatty acyl group on membrane lipoproteins
XNR_RS27300	COG1982	Orn Lys Arg decarboxylase major
XNR_RS27310	COG1968	undecaprenyl-diphosphatase activity
XNR_RS27330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XNR_RS27390	COG0110	maltose O-acetyltransferase activity
XNR_RS27400	COG1832	CoA-binding protein
XNR_RS27405	COG1739	Uncharacterized protein family UPF0029
XNR_RS27425	COG1595	DNA-templated transcription, initiation
XNR_RS27445	COG0420	3'-5' exonuclease activity
XNR_RS27450	COG0419	ATPase involved in DNA repair
XNR_RS27455	COG1522	sequence-specific DNA binding
XNR_RS27465	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS27480	COG0626	cystathionine gamma-synthase activity
XNR_RS27505	COG2188	Transcriptional regulator
XNR_RS27510	COG1940	carbohydrate kinase activity
XNR_RS27525	COG3663	DNA glycosylase
XNR_RS27530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XNR_RS27550	COG0456	acetyltransferase
XNR_RS27555	COG0488	(ABC) transporter
XNR_RS27560	COG0488	(ABC) transporter
XNR_RS27570	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XNR_RS27575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XNR_RS27580	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XNR_RS27605	COG0791	NLP P60 protein
XNR_RS27610	COG0740	serine-type endopeptidase activity
XNR_RS27620	COG0831	urea catabolic process
XNR_RS27625	COG0832	Belongs to the urease beta subunit family
XNR_RS27630	COG0804	urea catabolic process
XNR_RS27640	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XNR_RS27645	COG0829	nickel cation binding
XNR_RS27650	COG4552	Acetyltransferase involved in intracellular survival and related
XNR_RS27655	COG0204	Acyl-transferase
XNR_RS27700	COG2175	clavaminate synthase activity
XNR_RS27710	COG0435	Glutathione S-transferase
XNR_RS27725	COG2770	Histidine kinase
XNR_RS27725	COG2208	phosphoserine phosphatase activity
XNR_RS27740	COG0205	6-phosphofructokinase activity
XNR_RS27745	COG3442	glutamine amidotransferase
XNR_RS27755	COG0242	peptide deformylase activity
XNR_RS27765	COG1960	acyl-CoA dehydrogenase activity
XNR_RS27785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XNR_RS27810	COG1175	transmembrane transport
XNR_RS27815	COG0395	ABC-type sugar transport system, permease component
XNR_RS27820	COG2723	6-phospho-beta-galactosidase activity
XNR_RS27825	COG0501	Belongs to the peptidase M48B family
XNR_RS27870	COG4251	negative regulation of phosphorylation
XNR_RS27875	COG0784	Response regulator, receiver
XNR_RS27895	COG0656	L-ascorbic acid biosynthetic process
XNR_RS27905	COG1595	DNA-templated transcription, initiation
XNR_RS27915	COG1132	(ABC) transporter
XNR_RS27935	COG0697	spore germination
XNR_RS27940	COG0546	phosphoglycolate phosphatase activity
XNR_RS27945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XNR_RS27955	COG2313	pseudouridylate synthase activity
XNR_RS27960	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
XNR_RS27990	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XNR_RS27995	COG3279	Response regulator of the LytR AlgR family
XNR_RS28005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XNR_RS28010	COG3275	phosphorelay sensor kinase activity
XNR_RS28075	COG0583	DNA-binding transcription factor activity
XNR_RS28085	COG1053	succinate dehydrogenase
XNR_RS28090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XNR_RS28095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNR_RS28105	COG3360	Dodecin
XNR_RS28110	COG2182	Extracellular solute-binding protein
XNR_RS28115	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
XNR_RS28120	COG0121	glutamine amidotransferase
XNR_RS28125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XNR_RS28145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XNR_RS28150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XNR_RS28170	COG2837	iron assimilation
XNR_RS28180	COG1796	DNA polymerase
XNR_RS28180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
XNR_RS28185	COG0142	geranyltranstransferase activity
XNR_RS28225	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
XNR_RS28250	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XNR_RS28260	COG0254	rRNA binding
XNR_RS28265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XNR_RS28270	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XNR_RS28275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XNR_RS28300	COG0477	Major facilitator Superfamily
XNR_RS28330	COG3119	arylsulfatase activity
XNR_RS28345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XNR_RS28350	COG4948	Mandelate Racemase Muconate Lactonizing
XNR_RS28420	COG0464	growth
XNR_RS28440	COG3655	Transcriptional regulator
XNR_RS28460	COG0803	Belongs to the bacterial solute-binding protein 9 family
XNR_RS28470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XNR_RS28475	COG1121	(ABC) transporter
XNR_RS28480	COG0590	tRNA wobble adenosine to inosine editing
XNR_RS28485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
XNR_RS28515	COG2201	protein-glutamate methylesterase activity
XNR_RS28520	COG0300	oxidoreductase activity
XNR_RS28530	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XNR_RS28565	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XNR_RS28570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XNR_RS28575	COG1984	allophanate hydrolase subunit 2
XNR_RS28605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS28610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XNR_RS28615	COG1120	ATPase activity
XNR_RS28640	COG1132	(ABC) transporter
XNR_RS28645	COG1132	(ABC) transporter
XNR_RS28650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XNR_RS28660	COG0110	maltose O-acetyltransferase activity
XNR_RS28675	COG0242	peptide deformylase activity
XNR_RS28695	COG1349	DNA-binding transcription factor activity
XNR_RS28710	COG3395	kinase activity
XNR_RS28715	COG0235	Class ii aldolase
XNR_RS28745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNR_RS28755	COG4608	Belongs to the ABC transporter superfamily
XNR_RS28760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XNR_RS28775	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS28795	COG1174	glycine betaine transport
XNR_RS28800	COG1174	glycine betaine transport
XNR_RS28810	COG1125	glycine betaine transport
XNR_RS28810	COG0517	IMP dehydrogenase activity
XNR_RS28835	COG1960	acyl-CoA dehydrogenase activity
XNR_RS28840	COG1960	acyl-CoA dehydrogenase activity
XNR_RS28850	COG0601	transmembrane transport
XNR_RS28855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XNR_RS28860	COG0444	Belongs to the ABC transporter superfamily
XNR_RS28865	COG1124	(ABC) transporter
XNR_RS28875	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
XNR_RS28880	COG2318	DinB family
XNR_RS28905	COG0277	FAD linked oxidase domain protein
XNR_RS28910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
XNR_RS28920	COG2271	Major facilitator Superfamily
XNR_RS28970	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS28980	COG0142	geranyltranstransferase activity
XNR_RS29020	COG3321	synthase
XNR_RS29020	COG0604	alcohol dehydrogenase
XNR_RS29035	COG0604	alcohol dehydrogenase
XNR_RS29035	COG3321	synthase
XNR_RS29050	COG3321	synthase
XNR_RS29050	COG0604	alcohol dehydrogenase
XNR_RS29070	COG2124	cytochrome p450
XNR_RS29075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XNR_RS29110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XNR_RS29120	COG1129	ABC transporter
XNR_RS29150	COG3483	tryptophan 2,3-dioxygenase activity
XNR_RS29155	COG1028	Short-chain dehydrogenase reductase Sdr
XNR_RS29160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XNR_RS29165	COG2151	metal-sulfur cluster biosynthetic enzyme
XNR_RS29170	COG3396	Phenylacetate-CoA oxygenase
XNR_RS29180	COG3396	Phenylacetate-CoA oxygenase
XNR_RS29195	COG0604	alcohol dehydrogenase
XNR_RS29205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
XNR_RS29255	COG0515	serine threonine protein kinase
XNR_RS29285	COG1404	Belongs to the peptidase S8 family
XNR_RS29330	COG4221	oxidoreductase activity
XNR_RS29330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XNR_RS29330	COG0300	oxidoreductase activity
XNR_RS29330	COG3321	synthase
XNR_RS29340	COG4335	DNA alkylation repair
XNR_RS29365	COG0477	Major facilitator Superfamily
XNR_RS29395	COG3246	L-lysine catabolic process to acetate
XNR_RS29400	COG1250	3-hydroxyacyl-CoA dehydrogenase