locus-tag	class	description
DUI70_RS00060	COG0028	Belongs to the TPP enzyme family
DUI70_RS00065	COG2072	flavoprotein involved in K transport
DUI70_RS00075	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS00085	COG1024	Enoyl-CoA hydratase
DUI70_RS00115	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS00120	COG2124	cytochrome p450
DUI70_RS00130	COG1309	transcriptional regulator
DUI70_RS00140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DUI70_RS00145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DUI70_RS00155	COG3485	protocatechuate 3,4-dioxygenase
DUI70_RS00165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DUI70_RS00170	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DUI70_RS00175	COG1414	Transcriptional regulator
DUI70_RS00190	COG4120	Belongs to the binding-protein-dependent transport system permease family
DUI70_RS00195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DUI70_RS00205	COG1024	Enoyl-CoA hydratase
DUI70_RS00215	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS00220	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS00235	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS00240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DUI70_RS00260	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS00265	COG0183	Belongs to the thiolase family
DUI70_RS00270	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS00275	COG2267	carboxylic ester hydrolase activity
DUI70_RS00280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DUI70_RS00295	COG1024	Enoyl-CoA hydratase
DUI70_RS00300	COG1024	Enoyl-CoA hydratase
DUI70_RS00305	COG1024	Enoyl-CoA hydratase
DUI70_RS00315	COG4638	Rieske (2fe-2S)
DUI70_RS00320	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DUI70_RS00330	COG0427	acetyl-CoA hydrolase
DUI70_RS00335	COG0183	Belongs to the thiolase family
DUI70_RS00345	COG0183	Belongs to the thiolase family
DUI70_RS00350	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS00365	COG2301	Belongs to the HpcH HpaI aldolase family
DUI70_RS00370	COG2030	dehydratase
DUI70_RS00395	COG1733	regulation of RNA biosynthetic process
DUI70_RS00425	COG2186	Transcriptional regulator
DUI70_RS00440	COG0765	amino acid transport
DUI70_RS00455	COG0667	Aldo Keto reductase
DUI70_RS00475	COG2207	Transcriptional regulator
DUI70_RS00495	COG1309	transcriptional regulator
DUI70_RS00505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS00510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DUI70_RS00515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS00515	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS00515	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS00515	COG3321	synthase
DUI70_RS00515	COG0300	oxidoreductase activity
DUI70_RS00540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS00545	COG4221	oxidoreductase activity
DUI70_RS00570	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS00570	COG4221	oxidoreductase activity
DUI70_RS00570	COG3321	synthase
DUI70_RS00570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS00635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS00635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS00690	COG0105	UTP biosynthetic process
DUI70_RS00700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DUI70_RS00710	COG0667	Aldo Keto reductase
DUI70_RS00720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DUI70_RS00725	COG4569	acetaldehyde dehydrogenase (acetylating) activity
DUI70_RS00760	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS00780	COG2376	Dihydroxyacetone kinase
DUI70_RS00785	COG2376	Dihydroxyacetone kinase
DUI70_RS00795	COG0129	dihydroxy-acid dehydratase activity
DUI70_RS00800	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS00875	COG2318	DinB family
DUI70_RS00880	COG3467	pyridoxamine 5'-phosphate
DUI70_RS00885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DUI70_RS00890	COG1132	(ABC) transporter
DUI70_RS00910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DUI70_RS00925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS00940	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DUI70_RS00945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DUI70_RS00980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DUI70_RS00990	COG0789	Transcriptional regulator
DUI70_RS01020	COG0583	DNA-binding transcription factor activity
DUI70_RS01045	COG3724	N-succinylarginine dihydrolase activity
DUI70_RS01100	COG2115	Belongs to the xylose isomerase family
DUI70_RS01105	COG1940	carbohydrate kinase activity
DUI70_RS01115	COG2188	Transcriptional regulator
DUI70_RS01125	COG2182	Extracellular solute-binding protein
DUI70_RS01130	COG1175	transmembrane transport
DUI70_RS01135	COG0395	ABC-type sugar transport system, permease component
DUI70_RS01145	COG2706	6-phosphogluconolactonase activity
DUI70_RS01195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS01225	COG3559	Exporter of polyketide antibiotics
DUI70_RS01230	COG1131	(ABC) transporter
DUI70_RS01245	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DUI70_RS01310	COG3321	synthase
DUI70_RS01310	COG0604	alcohol dehydrogenase
DUI70_RS01315	COG3321	synthase
DUI70_RS01315	COG0604	alcohol dehydrogenase
DUI70_RS01325	COG1250	3-hydroxyacyl-CoA dehydrogenase
DUI70_RS01345	COG2814	Major facilitator Superfamily
DUI70_RS01350	COG1063	alcohol dehydrogenase
DUI70_RS01355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DUI70_RS01360	COG1834	amidinotransferase
DUI70_RS01390	COG0330	HflC and HflK could
DUI70_RS01430	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS01440	COG0515	serine threonine protein kinase
DUI70_RS01470	COG0395	ABC-type sugar transport system, permease component
DUI70_RS01475	COG1175	transmembrane transport
DUI70_RS01510	COG2376	Dihydroxyacetone kinase
DUI70_RS01515	COG1461	Dihydroxyacetone kinase
DUI70_RS01535	COG1902	pentaerythritol trinitrate reductase activity
DUI70_RS01535	COG0446	pyridine nucleotide-disulphide oxidoreductase
DUI70_RS01555	COG0435	Glutathione S-transferase
DUI70_RS01575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DUI70_RS01580	COG1215	transferase activity, transferring glycosyl groups
DUI70_RS01605	COG1349	DNA-binding transcription factor activity
DUI70_RS01625	COG0577	efflux transmembrane transporter activity
DUI70_RS01630	COG1136	(ABC) transporter
DUI70_RS01645	COG1940	carbohydrate kinase activity
DUI70_RS01655	COG0191	fructose-bisphosphate aldolase activity
DUI70_RS01660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DUI70_RS01665	COG1349	DNA-binding transcription factor activity
DUI70_RS01695	COG2197	response regulator
DUI70_RS01700	COG4585	Histidine kinase
DUI70_RS01705	COG0445	tRNA wobble uridine modification
DUI70_RS01720	COG0477	Major facilitator Superfamily
DUI70_RS01725	COG1051	belongs to the nudix hydrolase family
DUI70_RS01745	COG0515	serine threonine protein kinase
DUI70_RS01755	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DUI70_RS01780	COG0204	Acyl-transferase
DUI70_RS01810	COG0584	glycerophosphoryl diester phosphodiesterase
DUI70_RS01850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DUI70_RS01860	COG0488	(ABC) transporter
DUI70_RS01870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DUI70_RS01880	COG1113	amino acid transport
DUI70_RS01885	COG0789	Transcriptional regulator
DUI70_RS01890	COG1250	3-hydroxyacyl-CoA dehydrogenase
DUI70_RS01890	COG1024	Enoyl-CoA hydratase
DUI70_RS01895	COG0183	Belongs to the thiolase family
DUI70_RS01900	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS01905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DUI70_RS01910	COG3268	Saccharopine dehydrogenase
DUI70_RS01915	COG1515	deoxyribonuclease V activity
DUI70_RS01930	COG0488	(ABC) transporter
DUI70_RS01955	COG1793	dna ligase
DUI70_RS01970	COG1672	PFAM Archaeal ATPase
DUI70_RS01970	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DUI70_RS02005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DUI70_RS02010	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DUI70_RS02040	COG2154	pterin-4-alpha-carbinolamine dehydratase
DUI70_RS02065	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DUI70_RS02105	COG0457	Tetratricopeptide repeat
DUI70_RS02110	COG0456	acetyltransferase
DUI70_RS02110	COG0454	-acetyltransferase
DUI70_RS02120	COG1619	proteins homologs of microcin C7 resistance protein MccF
DUI70_RS02130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DUI70_RS02135	COG2362	D-Aminopeptidase
DUI70_RS02180	COG1250	3-hydroxyacyl-CoA dehydrogenase
DUI70_RS02195	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DUI70_RS02195	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DUI70_RS02200	COG2301	Belongs to the HpcH HpaI aldolase family
DUI70_RS02210	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS02215	COG0688	phosphatidylethanolamine metabolic process
DUI70_RS02225	COG1929	Belongs to the glycerate kinase type-1 family
DUI70_RS02230	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DUI70_RS02260	COG3511	phospholipase C
DUI70_RS02275	COG0395	ABC-type sugar transport system, permease component
DUI70_RS02300	COG0596	Alpha beta hydrolase
DUI70_RS02310	COG1609	Transcriptional regulator
DUI70_RS02320	COG1175	transmembrane transport
DUI70_RS02325	COG3833	ABC-type maltose transport systems, permease component
DUI70_RS02330	COG0366	Alpha amylase catalytic
DUI70_RS02350	COG0483	inositol monophosphate 1-phosphatase activity
DUI70_RS02385	COG0405	Gamma-glutamyltransferase
DUI70_RS02405	COG1357	PFAM Pentapeptide repeats (8 copies)
DUI70_RS02420	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DUI70_RS02440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DUI70_RS02445	COG0765	amino acid transport
DUI70_RS02465	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS02470	COG1794	racemase activity, acting on amino acids and derivatives
DUI70_RS02555	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS02560	COG1809	phosphosulfolactate synthase activity
DUI70_RS02570	COG1132	(ABC) transporter
DUI70_RS02575	COG1132	(ABC) transporter
DUI70_RS02590	COG0395	ABC-type sugar transport system, permease component
DUI70_RS02595	COG1175	transmembrane transport
DUI70_RS02635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DUI70_RS02650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DUI70_RS02660	COG1940	carbohydrate kinase activity
DUI70_RS02680	COG2188	Transcriptional regulator
DUI70_RS02685	COG0673	inositol 2-dehydrogenase activity
DUI70_RS02695	COG2197	response regulator
DUI70_RS02720	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS02725	COG4266	Belongs to the allantoicase family
DUI70_RS02730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DUI70_RS02745	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DUI70_RS02760	COG1940	carbohydrate kinase activity
DUI70_RS02765	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DUI70_RS02770	COG2223	nitrite transmembrane transporter activity
DUI70_RS02780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DUI70_RS02795	COG0438	transferase activity, transferring glycosyl groups
DUI70_RS02800	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS02810	COG1940	carbohydrate kinase activity
DUI70_RS02825	COG1082	Xylose isomerase domain protein TIM barrel
DUI70_RS02845	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS02845	COG3321	synthase
DUI70_RS02845	COG0604	alcohol dehydrogenase
DUI70_RS02855	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS02860	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS02870	COG1309	transcriptional regulator
DUI70_RS02875	COG1902	pentaerythritol trinitrate reductase activity
DUI70_RS02875	COG0446	pyridine nucleotide-disulphide oxidoreductase
DUI70_RS02880	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS02895	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS02900	COG1733	regulation of RNA biosynthetic process
DUI70_RS02905	COG0436	Aminotransferase
DUI70_RS02910	COG0406	alpha-ribazole phosphatase activity
DUI70_RS02960	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS02965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DUI70_RS02990	COG2340	Cysteine-rich secretory protein family
DUI70_RS02995	COG2186	Transcriptional regulator
DUI70_RS03005	COG1129	ABC transporter
DUI70_RS03015	COG0179	Fumarylacetoacetate (FAA) hydrolase
DUI70_RS03020	COG4948	Mandelate Racemase Muconate Lactonizing
DUI70_RS03035	COG0247	lactate metabolic process
DUI70_RS03040	COG1139	Iron-sulfur cluster binding protein
DUI70_RS03045	COG1556	Lactate utilization protein
DUI70_RS03075	COG1672	PFAM Archaeal ATPase
DUI70_RS03075	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DUI70_RS03095	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DUI70_RS03100	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DUI70_RS03105	COG2080	2 iron, 2 sulfur cluster binding
DUI70_RS03140	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DUI70_RS03140	COG3608	succinylglutamate desuccinylase aspartoacylase
DUI70_RS03145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DUI70_RS03175	COG1802	Transcriptional regulator
DUI70_RS03205	COG0028	Belongs to the TPP enzyme family
DUI70_RS03225	COG1819	glycosyl
DUI70_RS03240	COG3629	intracellular signal transduction
DUI70_RS03260	COG2124	cytochrome p450
DUI70_RS03270	COG2197	response regulator
DUI70_RS03290	COG0604	alcohol dehydrogenase
DUI70_RS03290	COG3321	synthase
DUI70_RS03295	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DUI70_RS03300	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DUI70_RS03315	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DUI70_RS03320	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DUI70_RS03335	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS03345	COG0604	alcohol dehydrogenase
DUI70_RS03345	COG3321	synthase
DUI70_RS03360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DUI70_RS03390	COG1309	transcriptional regulator
DUI70_RS03405	COG0604	alcohol dehydrogenase
DUI70_RS03405	COG3321	synthase
DUI70_RS03410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DUI70_RS03430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DUI70_RS03440	COG1162	GTPase activity
DUI70_RS03445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DUI70_RS03465	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DUI70_RS03470	COG0765	amino acid transport
DUI70_RS03485	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS03545	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS03565	COG0175	sulfate reduction
DUI70_RS03570	COG0529	Catalyzes the synthesis of activated sulfate
DUI70_RS03595	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DUI70_RS03600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DUI70_RS03610	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DUI70_RS03625	COG2409	Drug exporters of the RND superfamily
DUI70_RS03650	COG1175	transmembrane transport
DUI70_RS03660	COG0539	negative regulation of cytoplasmic translation
DUI70_RS03715	COG1191	sigma factor activity
DUI70_RS03730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DUI70_RS03735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DUI70_RS03795	COG3220	belongs to the UPF0276 family
DUI70_RS03815	COG3253	May function as heme-dependent peroxidase
DUI70_RS03820	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DUI70_RS03825	COG0446	pyridine nucleotide-disulphide oxidoreductase
DUI70_RS03835	COG0438	transferase activity, transferring glycosyl groups
DUI70_RS03845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DUI70_RS03850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DUI70_RS03870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DUI70_RS03885	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DUI70_RS03890	COG0183	Belongs to the thiolase family
DUI70_RS03895	COG1024	Enoyl-CoA hydratase
DUI70_RS03895	COG1250	3-hydroxyacyl-CoA dehydrogenase
DUI70_RS03910	COG0741	lytic transglycosylase activity
DUI70_RS03910	COG0739	heme binding
DUI70_RS03910	COG1196	nuclear chromosome segregation
DUI70_RS03915	COG0531	amino acid
DUI70_RS03920	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DUI70_RS03925	COG4214	carbohydrate transport
DUI70_RS03935	COG4213	ABC transporter substrate-binding protein
DUI70_RS03940	COG1940	carbohydrate kinase activity
DUI70_RS03985	COG0395	ABC-type sugar transport system, permease component
DUI70_RS03995	COG1653	transport
DUI70_RS04000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DUI70_RS04005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DUI70_RS04020	COG1472	Belongs to the glycosyl hydrolase 3 family
DUI70_RS04025	COG2066	Belongs to the glutaminase family
DUI70_RS04035	COG0745	RESPONSE REGULATOR receiver
DUI70_RS04040	COG2205	protein histidine kinase activity
DUI70_RS04065	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS04075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DUI70_RS04095	COG0395	ABC-type sugar transport system, permease component
DUI70_RS04110	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS04140	COG2208	phosphoserine phosphatase activity
DUI70_RS04140	COG2172	sigma factor antagonist activity
DUI70_RS04140	COG1366	Belongs to the anti-sigma-factor antagonist family
DUI70_RS04170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DUI70_RS04200	COG1799	cell septum assembly
DUI70_RS04205	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DUI70_RS04225	COG2814	Major facilitator Superfamily
DUI70_RS04235	COG0477	Major facilitator Superfamily
DUI70_RS04240	COG3321	synthase
DUI70_RS04240	COG0604	alcohol dehydrogenase
DUI70_RS04260	COG3321	synthase
DUI70_RS04260	COG0604	alcohol dehydrogenase
DUI70_RS04260	COG0604	alcohol dehydrogenase
DUI70_RS04260	COG3321	synthase
DUI70_RS04280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DUI70_RS04285	COG1819	glycosyl
DUI70_RS04300	COG0604	alcohol dehydrogenase
DUI70_RS04300	COG3321	synthase
DUI70_RS04305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DUI70_RS04320	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DUI70_RS04335	COG1773	rubredoxin
DUI70_RS04345	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DUI70_RS04350	COG1309	transcriptional regulator
DUI70_RS04355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DUI70_RS04400	COG4865	methylaspartate mutase activity
DUI70_RS04435	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS04460	COG4948	Mandelate Racemase Muconate Lactonizing
DUI70_RS04515	COG3629	intracellular signal transduction
DUI70_RS04515	COG3903	Transcriptional regulator
DUI70_RS04535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DUI70_RS04555	COG0667	Aldo Keto reductase
DUI70_RS04560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS04565	COG1116	anion transmembrane transporter activity
DUI70_RS04570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DUI70_RS04585	COG1940	carbohydrate kinase activity
DUI70_RS04585	COG1846	Transcriptional regulator
DUI70_RS04615	COG1021	2,3-dihydroxybenzoate-AMP ligase
DUI70_RS04620	COG1169	isochorismate synthase
DUI70_RS04625	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS04640	COG4977	sequence-specific DNA binding
DUI70_RS04650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DUI70_RS04655	COG0395	ABC-type sugar transport system, permease component
DUI70_RS04690	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DUI70_RS04720	COG0673	inositol 2-dehydrogenase activity
DUI70_RS04725	COG2172	sigma factor antagonist activity
DUI70_RS04725	COG2208	phosphoserine phosphatase activity
DUI70_RS04725	COG1366	Belongs to the anti-sigma-factor antagonist family
DUI70_RS04790	COG0438	transferase activity, transferring glycosyl groups
DUI70_RS04835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DUI70_RS04835	COG0515	serine threonine protein kinase
DUI70_RS04855	COG0395	ABC-type sugar transport system, permease component
DUI70_RS04860	COG1063	alcohol dehydrogenase
DUI70_RS04875	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS04880	COG1309	transcriptional regulator
DUI70_RS04915	COG3537	Alpha-1,2-mannosidase
DUI70_RS04925	COG2133	pyrroloquinoline quinone binding
DUI70_RS04925	COG5183	chlorophyll binding
DUI70_RS04930	COG1609	Transcriptional regulator
DUI70_RS04935	COG1879	ABC-type sugar transport system periplasmic component
DUI70_RS04940	COG1129	ABC transporter
DUI70_RS04945	COG1172	Belongs to the binding-protein-dependent transport system permease family
DUI70_RS04950	COG1172	Belongs to the binding-protein-dependent transport system permease family
DUI70_RS04980	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DUI70_RS04980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DUI70_RS05000	COG1174	glycine betaine transport
DUI70_RS05065	COG0009	L-threonylcarbamoyladenylate synthase
DUI70_RS05085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DUI70_RS05110	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DUI70_RS05115	COG0142	geranyltranstransferase activity
DUI70_RS05130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DUI70_RS05150	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DUI70_RS05155	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DUI70_RS05185	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DUI70_RS05190	COG2409	Drug exporters of the RND superfamily
DUI70_RS05195	COG3629	intracellular signal transduction
DUI70_RS05195	COG3903	Transcriptional regulator
DUI70_RS05200	COG2843	Capsule synthesis protein
DUI70_RS05215	COG0142	geranyltranstransferase activity
DUI70_RS05235	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DUI70_RS05290	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DUI70_RS05295	COG1335	isochorismatase
DUI70_RS05300	COG0473	3-isopropylmalate dehydrogenase activity
DUI70_RS05320	COG4221	oxidoreductase activity
DUI70_RS05345	COG0747	negative chemotaxis
DUI70_RS05355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DUI70_RS05365	COG4608	Belongs to the ABC transporter superfamily
DUI70_RS05370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS05385	COG0431	NADPH-dependent FMN reductase
DUI70_RS05395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS05400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS05410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS05470	COG1940	carbohydrate kinase activity
DUI70_RS05475	COG0395	ABC-type sugar transport system, permease component
DUI70_RS05480	COG1175	transmembrane transport
DUI70_RS05490	COG1063	alcohol dehydrogenase
DUI70_RS05495	COG1082	Xylose isomerase domain protein TIM barrel
DUI70_RS05500	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
DUI70_RS05510	COG4974	Belongs to the 'phage' integrase family
DUI70_RS05550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DUI70_RS05570	COG3387	PFAM Glycoside hydrolase 15-related
DUI70_RS05640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DUI70_RS05650	COG1132	(ABC) transporter
DUI70_RS05665	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DUI70_RS05705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DUI70_RS05730	COG0154	amidase activity
DUI70_RS05850	COG0640	Transcriptional regulator
DUI70_RS05870	COG1742	UPF0060 membrane protein
DUI70_RS05880	COG2072	flavoprotein involved in K transport
DUI70_RS05885	COG0798	PFAM Bile acid sodium symporter
DUI70_RS05895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DUI70_RS05900	COG0492	ferredoxin-NADP+ reductase activity
DUI70_RS05910	COG2259	Doxx family
DUI70_RS05915	COG1695	Transcriptional regulator
DUI70_RS05935	COG0671	phosphoesterase, PA-phosphatase related
DUI70_RS05940	COG1968	undecaprenyl-diphosphatase activity
DUI70_RS05950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DUI70_RS05955	COG1993	acr, cog1993
DUI70_RS05960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DUI70_RS06015	COG0693	protein deglycase activity
DUI70_RS06050	COG0656	L-ascorbic acid biosynthetic process
DUI70_RS06065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DUI70_RS06075	COG2132	Multicopper oxidase
DUI70_RS06080	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DUI70_RS06090	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DUI70_RS06100	COG0713	ATP synthesis coupled electron transport
DUI70_RS06105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DUI70_RS06115	COG1007	ATP synthesis coupled electron transport
DUI70_RS06240	COG0791	NLP P60 protein
DUI70_RS06240	COG3883	PFAM NLP P60 protein
DUI70_RS06350	COG0714	Associated with various cellular activities
DUI70_RS06470	COG0159	tryptophan synthase activity
DUI70_RS06500	COG1278	Cold shock
DUI70_RS06515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DUI70_RS06540	COG0582	viral genome integration into host DNA
DUI70_RS06600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DUI70_RS06605	COG0531	amino acid
DUI70_RS06610	COG0569	domain protein
DUI70_RS06650	COG0756	dUTP diphosphatase activity
DUI70_RS06675	COG2205	protein histidine kinase activity
DUI70_RS06680	COG0745	RESPONSE REGULATOR receiver
DUI70_RS06690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DUI70_RS06725	COG1435	thymidine kinase activity
DUI70_RS06745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DUI70_RS06750	COG1802	Transcriptional regulator
DUI70_RS06755	COG0739	heme binding
DUI70_RS06765	COG0612	Peptidase, M16
DUI70_RS06770	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DUI70_RS06785	COG0372	Belongs to the citrate synthase family
DUI70_RS06800	COG3290	protein histidine kinase activity
DUI70_RS06810	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DUI70_RS06830	COG0187	DNA topoisomerase II activity
DUI70_RS06845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DUI70_RS06850	COG2186	Transcriptional regulator
DUI70_RS06890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DUI70_RS06915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DUI70_RS06920	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DUI70_RS06930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DUI70_RS06945	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS06990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DUI70_RS07005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DUI70_RS07030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DUI70_RS07055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DUI70_RS07060	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DUI70_RS07070	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DUI70_RS07085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DUI70_RS07110	COG1609	Transcriptional regulator
DUI70_RS07115	COG1653	transport
DUI70_RS07120	COG1175	transmembrane transport
DUI70_RS07125	COG0395	ABC-type sugar transport system, permease component
DUI70_RS07150	COG1126	abc transporter atp-binding protein
DUI70_RS07155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DUI70_RS07160	COG0765	amino acid transport
DUI70_RS07165	COG0765	amino acid transport
DUI70_RS07185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DUI70_RS07200	COG2137	regulation of response to DNA damage stimulus
DUI70_RS07205	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DUI70_RS07240	COG1917	Cupin 2, conserved barrel domain protein
DUI70_RS07240	COG2207	Transcriptional regulator
DUI70_RS07245	COG1201	RNA secondary structure unwinding
DUI70_RS07250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DUI70_RS07255	COG0783	Belongs to the Dps family
DUI70_RS07260	COG1396	sequence-specific DNA binding
DUI70_RS07265	COG1546	Belongs to the CinA family
DUI70_RS07265	COG1058	Belongs to the CinA family
DUI70_RS07275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DUI70_RS07285	COG1674	ftsk spoiiie
DUI70_RS07295	COG3850	Histidine kinase
DUI70_RS07295	COG3437	response regulator, receiver
DUI70_RS07295	COG2205	protein histidine kinase activity
DUI70_RS07295	COG4999	Histidine kinase
DUI70_RS07300	COG2208	phosphoserine phosphatase activity
DUI70_RS07300	COG2770	Histidine kinase
DUI70_RS07330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DUI70_RS07335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DUI70_RS07340	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DUI70_RS07365	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DUI70_RS07370	COG0612	Peptidase, M16
DUI70_RS07375	COG1185	polyribonucleotide nucleotidyltransferase activity
DUI70_RS07380	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DUI70_RS07405	COG0455	bacterial-type flagellum organization
DUI70_RS07410	COG0747	negative chemotaxis
DUI70_RS07415	COG0601	transmembrane transport
DUI70_RS07420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DUI70_RS07445	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DUI70_RS07450	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DUI70_RS07460	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DUI70_RS07475	COG0779	Required for maturation of 30S ribosomal subunits
DUI70_RS07495	COG0442	prolyl-tRNA aminoacylation
DUI70_RS07510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DUI70_RS07515	COG0750	zinc metalloprotease
DUI70_RS07520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DUI70_RS07535	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS07540	COG2508	Transcriptional regulator
DUI70_RS07580	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DUI70_RS07600	COG5640	endopeptidase activity
DUI70_RS07605	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS07635	COG3842	ATPase activity
DUI70_RS07650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DUI70_RS07655	COG1725	Transcriptional regulator
DUI70_RS07685	COG0233	cytoplasmic translational termination
DUI70_RS07690	COG0528	UMP kinase activity
DUI70_RS07695	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DUI70_RS07700	COG0052	Belongs to the universal ribosomal protein uS2 family
DUI70_RS07715	COG1191	sigma factor activity
DUI70_RS07730	COG0789	Transcriptional regulator
DUI70_RS07765	COG0792	nuclease activity
DUI70_RS07775	COG1051	belongs to the nudix hydrolase family
DUI70_RS07780	COG0681	Belongs to the peptidase S26 family
DUI70_RS07790	COG0681	Belongs to the peptidase S26 family
DUI70_RS07800	COG0335	large ribosomal subunit rRNA binding
DUI70_RS07805	COG0336	Belongs to the RNA methyltransferase TrmD family
DUI70_RS07810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DUI70_RS07815	COG1837	Belongs to the UPF0109 family
DUI70_RS07820	COG0228	four-way junction DNA binding
DUI70_RS07845	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DUI70_RS07875	COG0477	Major facilitator Superfamily
DUI70_RS07880	COG1196	nuclear chromosome segregation
DUI70_RS07890	COG1254	Belongs to the acylphosphatase family
DUI70_RS07895	COG2340	Cysteine-rich secretory protein family
DUI70_RS07900	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DUI70_RS07905	COG0571	ribonuclease III activity
DUI70_RS07910	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DUI70_RS07925	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DUI70_RS07930	COG0742	ribosomal rna small subunit methyltransferase
DUI70_RS07935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DUI70_RS07940	COG0326	Molecular chaperone. Has ATPase activity
DUI70_RS07950	COG1461	Dihydroxyacetone kinase
DUI70_RS07955	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DUI70_RS07980	COG1181	Belongs to the D-alanine--D-alanine ligase family
DUI70_RS07985	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DUI70_RS07995	COG1920	GTP binding
DUI70_RS08005	COG0776	regulation of translation
DUI70_RS08015	COG0066	3-isopropylmalate dehydratase activity
DUI70_RS08020	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DUI70_RS08025	COG1414	Transcriptional regulator
DUI70_RS08070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DUI70_RS08075	COG0179	Fumarylacetoacetate (FAA) hydrolase
DUI70_RS08090	COG2018	Roadblock/LC7 domain
DUI70_RS08110	COG2018	Roadblock/LC7 domain
DUI70_RS08130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DUI70_RS08140	COG2353	YceI-like domain
DUI70_RS08155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DUI70_RS08160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DUI70_RS08165	COG0473	3-isopropylmalate dehydrogenase activity
DUI70_RS08180	COG0583	DNA-binding transcription factor activity
DUI70_RS08185	COG2130	NADP-dependent
DUI70_RS08195	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS08200	COG0506	proline dehydrogenase activity
DUI70_RS08205	COG3835	regulator
DUI70_RS08210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DUI70_RS08215	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DUI70_RS08220	COG0440	acetolactate synthase activity
DUI70_RS08240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DUI70_RS08250	COG1621	beta-fructofuranosidase activity
DUI70_RS08305	COG2409	Drug exporters of the RND superfamily
DUI70_RS08315	COG2207	Transcriptional regulator
DUI70_RS08315	COG3708	Transcriptional regulator
DUI70_RS08325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DUI70_RS08335	COG1196	nuclear chromosome segregation
DUI70_RS08345	COG0154	amidase activity
DUI70_RS08350	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DUI70_RS08360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DUI70_RS08370	COG4221	oxidoreductase activity
DUI70_RS08375	COG1611	Belongs to the LOG family
DUI70_RS08395	COG0482	sulfurtransferase activity
DUI70_RS08450	COG2378	regulation of single-species biofilm formation
DUI70_RS08460	COG2860	membrane
DUI70_RS08465	COG4608	Belongs to the ABC transporter superfamily
DUI70_RS08470	COG0444	Belongs to the ABC transporter superfamily
DUI70_RS08475	COG0601	transmembrane transport
DUI70_RS08480	COG0747	negative chemotaxis
DUI70_RS08505	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DUI70_RS08510	COG0509	glycine decarboxylation via glycine cleavage system
DUI70_RS08515	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DUI70_RS08520	COG1760	l-serine dehydratase
DUI70_RS08540	COG0259	pyridoxamine-phosphate oxidase activity
DUI70_RS08550	COG0148	phosphopyruvate hydratase activity
DUI70_RS08570	COG1063	alcohol dehydrogenase
DUI70_RS08575	COG1295	ribonuclease BN
DUI70_RS08605	COG1802	Transcriptional regulator
DUI70_RS08610	COG0006	proline dipeptidase activity
DUI70_RS08635	COG3391	amine dehydrogenase activity
DUI70_RS08670	COG1132	(ABC) transporter
DUI70_RS08675	COG1132	(ABC) transporter
DUI70_RS08680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DUI70_RS08685	COG1802	Transcriptional regulator
DUI70_RS08720	COG0058	SHG alpha-glucan phosphorylase activity
DUI70_RS08725	COG0366	Alpha amylase catalytic
DUI70_RS08735	COG3281	Trehalose synthase
DUI70_RS08785	COG4565	transcriptional regulatory protein
DUI70_RS08795	COG1175	transmembrane transport
DUI70_RS08800	COG3833	ABC-type maltose transport systems, permease component
DUI70_RS08835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DUI70_RS08855	COG0205	6-phosphofructokinase activity
DUI70_RS08860	COG0280	phosphate acetyltransferase
DUI70_RS08860	COG0857	belongs to the CobB CobQ family
DUI70_RS08865	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DUI70_RS08910	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DUI70_RS08910	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DUI70_RS08975	COG0745	RESPONSE REGULATOR receiver
DUI70_RS08990	COG0183	Belongs to the thiolase family
DUI70_RS09010	COG1131	(ABC) transporter
DUI70_RS09025	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DUI70_RS09030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DUI70_RS09060	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DUI70_RS09075	COG1250	3-hydroxyacyl-CoA dehydrogenase
DUI70_RS09080	COG1309	transcriptional regulator
DUI70_RS09100	COG1595	DNA-templated transcription, initiation
DUI70_RS09105	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DUI70_RS09120	COG3850	Histidine kinase
DUI70_RS09125	COG2197	response regulator
DUI70_RS09145	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DUI70_RS09150	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DUI70_RS09155	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DUI70_RS09160	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DUI70_RS09165	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DUI70_RS09170	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DUI70_RS09175	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DUI70_RS09190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DUI70_RS09195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DUI70_RS09200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DUI70_RS09210	COG2890	protein-(glutamine-N5) methyltransferase activity
DUI70_RS09215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DUI70_RS09220	COG0254	rRNA binding
DUI70_RS09245	COG0083	homoserine kinase activity
DUI70_RS09250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DUI70_RS09255	COG0460	homoserine dehydrogenase
DUI70_RS09260	COG0019	diaminopimelate decarboxylase activity
DUI70_RS09265	COG0018	arginyl-trna synthetase
DUI70_RS09275	COG3654	unkown
DUI70_RS09290	COG0745	RESPONSE REGULATOR receiver
DUI70_RS09310	COG0151	Belongs to the GarS family
DUI70_RS09325	COG0640	Transcriptional regulator
DUI70_RS09350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS09370	COG0326	Molecular chaperone. Has ATPase activity
DUI70_RS09385	COG0328	RNA-DNA hybrid ribonuclease activity
DUI70_RS09405	COG2890	protein-(glutamine-N5) methyltransferase activity
DUI70_RS09415	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DUI70_RS09420	COG1793	dna ligase
DUI70_RS09420	COG3285	dna ligase
DUI70_RS09435	COG0772	Belongs to the SEDS family
DUI70_RS09515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DUI70_RS09530	COG0745	RESPONSE REGULATOR receiver
DUI70_RS09535	COG2205	protein histidine kinase activity
DUI70_RS09540	COG0567	Dehydrogenase, E1 component
DUI70_RS09540	COG0508	dehydrogenase complex catalyzes the overall conversion of
DUI70_RS09550	COG2755	lipolytic protein G-D-S-L family
DUI70_RS09595	COG0604	alcohol dehydrogenase
DUI70_RS09620	COG1126	abc transporter atp-binding protein
DUI70_RS09625	COG4106	trans-aconitate 2-methyltransferase activity
DUI70_RS09650	COG1309	transcriptional regulator
DUI70_RS09715	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS09720	COG4941	Belongs to the sigma-70 factor family
DUI70_RS09745	COG0142	geranyltranstransferase activity
DUI70_RS09750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DUI70_RS09790	COG1597	lipid kinase activity
DUI70_RS09805	COG0363	glucosamine-6-phosphate deaminase activity
DUI70_RS09810	COG1472	Belongs to the glycosyl hydrolase 3 family
DUI70_RS09815	COG2188	Transcriptional regulator
DUI70_RS09840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DUI70_RS09845	COG2124	cytochrome p450
DUI70_RS09855	COG0242	peptide deformylase activity
DUI70_RS09875	COG5662	AntiSigma factor
DUI70_RS09880	COG1595	DNA-templated transcription, initiation
DUI70_RS09895	COG2135	peptidase activity
DUI70_RS09900	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DUI70_RS09905	COG1162	GTPase activity
DUI70_RS09910	COG2076	Multidrug Resistance protein
DUI70_RS09920	COG0483	inositol monophosphate 1-phosphatase activity
DUI70_RS09930	COG0753	catalase activity
DUI70_RS09965	COG1615	UPF0182 protein
DUI70_RS09975	COG3480	Lon protease (S16) C-terminal proteolytic domain
DUI70_RS10025	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DUI70_RS10090	COG0210	DNA helicase
DUI70_RS10120	COG0596	Alpha beta hydrolase
DUI70_RS10130	COG1733	regulation of RNA biosynthetic process
DUI70_RS10170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DUI70_RS10230	COG0542	response to heat
DUI70_RS10240	COG1432	Conserved Protein
DUI70_RS10245	COG2095	MarC family integral membrane protein
DUI70_RS10250	COG0613	PHP domain protein
DUI70_RS10260	COG2814	Major facilitator Superfamily
DUI70_RS10270	COG0598	Magnesium transport protein CorA
DUI70_RS10305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DUI70_RS10310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DUI70_RS10320	COG1595	DNA-templated transcription, initiation
DUI70_RS10335	COG1024	Enoyl-CoA hydratase
DUI70_RS10340	COG2818	Glycosylase
DUI70_RS10355	COG1611	Belongs to the LOG family
DUI70_RS10360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DUI70_RS10390	COG0456	acetyltransferase
DUI70_RS10390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DUI70_RS10400	COG2197	response regulator
DUI70_RS10405	COG4585	Histidine kinase
DUI70_RS10415	COG1131	(ABC) transporter
DUI70_RS10440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DUI70_RS10455	COG4608	Belongs to the ABC transporter superfamily
DUI70_RS10465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DUI70_RS10470	COG0601	transmembrane transport
DUI70_RS10505	COG1733	regulation of RNA biosynthetic process
DUI70_RS10520	COG0604	alcohol dehydrogenase
DUI70_RS10520	COG3321	synthase
DUI70_RS10565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DUI70_RS10595	COG4608	Belongs to the ABC transporter superfamily
DUI70_RS10600	COG0444	Belongs to the ABC transporter superfamily
DUI70_RS10615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DUI70_RS10620	COG1217	gtp-binding protein TYPA
DUI70_RS10665	COG0667	Aldo Keto reductase
DUI70_RS10710	COG1946	Acyl-CoA thioesterase
DUI70_RS10715	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS10735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DUI70_RS10745	COG2409	Drug exporters of the RND superfamily
DUI70_RS10880	COG0464	growth
DUI70_RS10915	COG0012	GTP binding
DUI70_RS10930	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DUI70_RS10935	COG1570	exodeoxyribonuclease VII activity
DUI70_RS10940	COG1722	exodeoxyribonuclease VII activity
DUI70_RS10945	COG0778	Nitroreductase
DUI70_RS10970	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DUI70_RS10970	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DUI70_RS10995	COG0114	fumarate hydratase activity
DUI70_RS11005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DUI70_RS11020	COG4977	sequence-specific DNA binding
DUI70_RS11030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DUI70_RS11050	COG1136	(ABC) transporter
DUI70_RS11070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DUI70_RS11085	COG0515	serine threonine protein kinase
DUI70_RS11090	COG2319	Wd-40 repeat
DUI70_RS11090	COG4249	Peptidase C14 caspase catalytic subunit p20
DUI70_RS11100	COG1309	transcriptional regulator
DUI70_RS11105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DUI70_RS11120	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS11160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DUI70_RS11165	COG0589	response to stress
DUI70_RS11170	COG4977	sequence-specific DNA binding
DUI70_RS11175	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DUI70_RS11190	COG0673	inositol 2-dehydrogenase activity
DUI70_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS11280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS11365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DUI70_RS11370	COG0154	amidase activity
DUI70_RS11380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DUI70_RS11385	COG0765	amino acid transport
DUI70_RS11390	COG0765	amino acid transport
DUI70_RS11395	COG1126	abc transporter atp-binding protein
DUI70_RS11450	COG2186	Transcriptional regulator
DUI70_RS11520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DUI70_RS11530	COG2188	Transcriptional regulator
DUI70_RS11535	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DUI70_RS11540	COG0477	Major facilitator Superfamily
DUI70_RS11550	COG0673	inositol 2-dehydrogenase activity
DUI70_RS11555	COG0706	membrane insertase activity
DUI70_RS11585	COG2271	Major facilitator Superfamily
DUI70_RS11590	COG2814	Major facilitator Superfamily
DUI70_RS11605	COG2733	membrane
DUI70_RS11625	COG1131	(ABC) transporter
DUI70_RS11640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DUI70_RS11670	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DUI70_RS11680	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DUI70_RS11685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DUI70_RS11690	COG1234	tRNA 3'-trailer cleavage
DUI70_RS11710	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DUI70_RS11715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DUI70_RS11730	COG1113	amino acid transport
DUI70_RS11740	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DUI70_RS11750	COG1335	isochorismatase
DUI70_RS11790	COG0277	FAD linked oxidase domain protein
DUI70_RS11795	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DUI70_RS11805	COG3480	Lon protease (S16) C-terminal proteolytic domain
DUI70_RS11840	COG1024	Enoyl-CoA hydratase
DUI70_RS11855	COG0300	oxidoreductase activity
DUI70_RS11875	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DUI70_RS11900	COG1678	Uncharacterized ACR, COG1678
DUI70_RS11905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DUI70_RS11910	COG0776	regulation of translation
DUI70_RS11920	COG3973	AAA domain
DUI70_RS11945	COG2223	nitrite transmembrane transporter activity
DUI70_RS11995	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DUI70_RS12000	COG0793	Belongs to the peptidase S41A family
DUI70_RS12000	COG3409	Peptidoglycan-binding domain 1 protein
DUI70_RS12010	COG2884	Cell division ATP-binding protein ftsE
DUI70_RS12025	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DUI70_RS12030	COG0515	serine threonine protein kinase
DUI70_RS12035	COG0515	serine threonine protein kinase
DUI70_RS12055	COG1175	transmembrane transport
DUI70_RS12060	COG0395	ABC-type sugar transport system, permease component
DUI70_RS12070	COG1764	response to oxidative stress
DUI70_RS12075	COG1846	Transcriptional regulator
DUI70_RS12085	COG2318	DinB family
DUI70_RS12125	COG2902	Dehydrogenase
DUI70_RS12145	COG0653	protein targeting
DUI70_RS12155	COG3214	Protein conserved in bacteria
DUI70_RS12160	COG2197	response regulator
DUI70_RS12165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DUI70_RS12170	COG1040	competence protein
DUI70_RS12175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DUI70_RS12180	COG0823	Involved in the tonB-independent uptake of proteins
DUI70_RS12185	COG5002	protein histidine kinase activity
DUI70_RS12190	COG0745	RESPONSE REGULATOR receiver
DUI70_RS12195	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DUI70_RS12215	COG0714	Associated with various cellular activities
DUI70_RS12260	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DUI70_RS12270	COG1482	cell wall glycoprotein biosynthetic process
DUI70_RS12280	COG2835	tetraacyldisaccharide 4'-kinase activity
DUI70_RS12285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DUI70_RS12325	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DUI70_RS12330	COG0778	Nitroreductase
DUI70_RS12330	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DUI70_RS12360	COG1316	TRANSCRIPTIONal
DUI70_RS12380	COG0366	Alpha amylase catalytic
DUI70_RS12385	COG0395	ABC-type sugar transport system, permease component
DUI70_RS12390	COG1175	transmembrane transport
DUI70_RS12425	COG1316	TRANSCRIPTIONal
DUI70_RS12435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DUI70_RS12460	COG2205	protein histidine kinase activity
DUI70_RS12465	COG0745	RESPONSE REGULATOR receiver
DUI70_RS12470	COG3104	oligopeptide transport
DUI70_RS12480	COG1366	Belongs to the anti-sigma-factor antagonist family
DUI70_RS12485	COG1191	sigma factor activity
DUI70_RS12490	COG1228	amidohydrolase
DUI70_RS12505	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DUI70_RS12510	COG0019	diaminopimelate decarboxylase activity
DUI70_RS12540	COG2755	lipolytic protein G-D-S-L family
DUI70_RS12545	COG0183	Belongs to the thiolase family
DUI70_RS12575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DUI70_RS12600	COG0148	phosphopyruvate hydratase activity
DUI70_RS12615	COG2124	cytochrome p450
DUI70_RS12650	COG0179	Fumarylacetoacetate (FAA) hydrolase
DUI70_RS12655	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS12660	COG2188	Transcriptional regulator
DUI70_RS12675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DUI70_RS12685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DUI70_RS12690	COG1733	regulation of RNA biosynthetic process
DUI70_RS12725	COG1007	ATP synthesis coupled electron transport
DUI70_RS12735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DUI70_RS12740	COG0713	ATP synthesis coupled electron transport
DUI70_RS12745	COG0839	Belongs to the complex I subunit 6 family
DUI70_RS12750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DUI70_RS12755	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DUI70_RS12760	COG1034	ATP synthesis coupled electron transport
DUI70_RS12765	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DUI70_RS12775	COG0649	NAD binding
DUI70_RS12780	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DUI70_RS12785	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DUI70_RS12820	COG2226	methyltransferase
DUI70_RS12830	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DUI70_RS12920	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
DUI70_RS13005	COG0494	nUDIX hydrolase
DUI70_RS13015	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DUI70_RS13020	COG1278	Cold shock
DUI70_RS13030	COG0183	Belongs to the thiolase family
DUI70_RS13035	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS13065	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DUI70_RS13075	COG0163	prenyltransferase activity
DUI70_RS13080	COG4257	antibiotic catabolic process
DUI70_RS13085	COG0110	maltose O-acetyltransferase activity
DUI70_RS13090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DUI70_RS13095	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DUI70_RS13130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DUI70_RS13150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DUI70_RS13155	COG1333	cytochrome c biogenesis protein
DUI70_RS13175	COG0406	alpha-ribazole phosphatase activity
DUI70_RS13180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DUI70_RS13225	COG1073	alpha beta
DUI70_RS13230	COG3537	Alpha-1,2-mannosidase
DUI70_RS13235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DUI70_RS13260	COG3973	AAA domain
DUI70_RS13270	COG0431	NADPH-dependent FMN reductase
DUI70_RS13295	COG1742	UPF0060 membrane protein
DUI70_RS13320	COG0018	arginyl-trna synthetase
DUI70_RS13325	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DUI70_RS13330	COG0477	Major facilitator Superfamily
DUI70_RS13350	COG1690	Belongs to the RtcB family
DUI70_RS13385	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DUI70_RS13385	COG0515	serine threonine protein kinase
DUI70_RS13390	COG0113	porphobilinogen synthase activity
DUI70_RS13395	COG1648	precorrin-2 dehydrogenase activity
DUI70_RS13395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DUI70_RS13400	COG0181	hydroxymethylbilane synthase activity
DUI70_RS13405	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DUI70_RS13410	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DUI70_RS13465	COG0123	including yeast histone deacetylase and acetoin utilization protein
DUI70_RS13470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DUI70_RS13495	COG0180	Tryptophanyl-tRNA synthetase
DUI70_RS13500	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DUI70_RS13510	COG1129	ABC transporter
DUI70_RS13510	COG0842	Transport permease protein
DUI70_RS13540	COG0129	dihydroxy-acid dehydratase activity
DUI70_RS13555	COG1082	Xylose isomerase domain protein TIM barrel
DUI70_RS13560	COG0248	Ppx GppA phosphatase
DUI70_RS13580	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DUI70_RS13600	COG3387	PFAM Glycoside hydrolase 15-related
DUI70_RS13615	COG0667	Aldo Keto reductase
DUI70_RS13640	COG0673	inositol 2-dehydrogenase activity
DUI70_RS13645	COG1879	ABC-type sugar transport system periplasmic component
DUI70_RS13650	COG1172	Belongs to the binding-protein-dependent transport system permease family
DUI70_RS13665	COG1940	carbohydrate kinase activity
DUI70_RS13685	COG1194	a g-specific adenine glycosylase
DUI70_RS13700	COG0745	RESPONSE REGULATOR receiver
DUI70_RS13705	COG2205	protein histidine kinase activity
DUI70_RS13725	COG0739	heme binding
DUI70_RS13755	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DUI70_RS13775	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DUI70_RS13785	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DUI70_RS13790	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DUI70_RS13815	COG1660	Displays ATPase and GTPase activities
DUI70_RS13820	COG2197	response regulator
DUI70_RS13835	COG0649	NAD binding
DUI70_RS13860	COG1174	glycine betaine transport
DUI70_RS13865	COG1174	glycine betaine transport
DUI70_RS13870	COG0517	IMP dehydrogenase activity
DUI70_RS13870	COG1125	glycine betaine transport
DUI70_RS13875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DUI70_RS13885	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DUI70_RS13905	COG0302	gtp cyclohydrolase
DUI70_RS13920	COG0037	tRNA processing
DUI70_RS13930	COG2027	D-alanyl-D-alanine carboxypeptidase
DUI70_RS13935	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DUI70_RS13945	COG0586	Pfam SNARE associated Golgi protein
DUI70_RS13950	COG0789	Transcriptional regulator
DUI70_RS13955	COG0076	glutamate decarboxylase activity
DUI70_RS13975	COG2318	DinB family
DUI70_RS13980	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS14005	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DUI70_RS14010	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DUI70_RS14015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DUI70_RS14020	COG0254	rRNA binding
DUI70_RS14030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DUI70_RS14070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DUI70_RS14070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DUI70_RS14135	COG1674	ftsk spoiiie
DUI70_RS14220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DUI70_RS14225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DUI70_RS14230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DUI70_RS14230	COG1754	DNA topoisomerase type I activity
DUI70_RS14235	COG2890	protein-(glutamine-N5) methyltransferase activity
DUI70_RS14245	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DUI70_RS14250	COG2172	sigma factor antagonist activity
DUI70_RS14255	COG1366	Belongs to the anti-sigma-factor antagonist family
DUI70_RS14260	COG1205	dead DEAH box helicase
DUI70_RS14260	COG1111	helicase
DUI70_RS14325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DUI70_RS14335	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DUI70_RS14345	COG2267	carboxylic ester hydrolase activity
DUI70_RS14380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DUI70_RS14390	COG0251	oxidation-reduction process
DUI70_RS14405	COG0003	Pfam Anion-transporting ATPase
DUI70_RS14420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DUI70_RS14430	COG1408	metallophosphoesterase
DUI70_RS14485	COG0546	phosphoglycolate phosphatase activity
DUI70_RS14540	COG0515	serine threonine protein kinase
DUI70_RS14540	COG2815	serine threonine protein kinase
DUI70_RS14590	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS14605	COG4175	Glycine betaine
DUI70_RS14605	COG0517	IMP dehydrogenase activity
DUI70_RS14610	COG4176	ABC-type proline glycine betaine transport system permease component
DUI70_RS14635	COG2197	response regulator
DUI70_RS14680	COG2255	four-way junction helicase activity
DUI70_RS14685	COG1609	Transcriptional regulator
DUI70_RS14705	COG2304	oxidoreductase activity
DUI70_RS14735	COG0438	transferase activity, transferring glycosyl groups
DUI70_RS14740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DUI70_RS14750	COG0728	peptidoglycan biosynthetic process
DUI70_RS14840	COG1595	DNA-templated transcription, initiation
DUI70_RS14855	COG0515	serine threonine protein kinase
DUI70_RS14855	COG2815	serine threonine protein kinase
DUI70_RS14865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DUI70_RS14870	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DUI70_RS14885	COG1802	Transcriptional regulator
DUI70_RS14890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DUI70_RS14920	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DUI70_RS14935	COG1131	(ABC) transporter
DUI70_RS14940	COG3559	Exporter of polyketide antibiotics
DUI70_RS14945	COG2124	cytochrome p450
DUI70_RS14955	COG3844	kynureninase activity
DUI70_RS14975	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
DUI70_RS14990	COG0191	fructose-bisphosphate aldolase activity
DUI70_RS14995	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DUI70_RS15010	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DUI70_RS15065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DUI70_RS15080	COG1595	DNA-templated transcription, initiation
DUI70_RS15095	COG0542	response to heat
DUI70_RS15140	COG0789	Transcriptional regulator
DUI70_RS15145	COG0484	heat shock protein binding
DUI70_RS15150	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DUI70_RS15155	COG0443	Heat shock 70 kDa protein
DUI70_RS15160	COG0247	lactate metabolic process
DUI70_RS15160	COG2181	nitrate reductase activity
DUI70_RS15170	COG1595	DNA-templated transcription, initiation
DUI70_RS15180	COG0596	Alpha beta hydrolase
DUI70_RS15205	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DUI70_RS15210	COG0717	Belongs to the dCTP deaminase family
DUI70_RS15305	COG0798	PFAM Bile acid sodium symporter
DUI70_RS15315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DUI70_RS15320	COG0640	Transcriptional regulator
DUI70_RS15330	COG0673	inositol 2-dehydrogenase activity
DUI70_RS15340	COG3321	synthase
DUI70_RS15340	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS15340	COG0604	alcohol dehydrogenase
DUI70_RS15345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DUI70_RS15350	COG0586	Pfam SNARE associated Golgi protein
DUI70_RS15355	COG0028	Belongs to the TPP enzyme family
DUI70_RS15355	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
DUI70_RS15365	COG0477	Major facilitator Superfamily
DUI70_RS15380	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DUI70_RS15385	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DUI70_RS15390	COG3002	Belongs to the UPF0753 family
DUI70_RS15395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DUI70_RS15400	COG0573	inorganic phosphate transmembrane transporter activity
DUI70_RS15405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DUI70_RS15410	COG0640	Transcriptional regulator
DUI70_RS15415	COG0640	Transcriptional regulator
DUI70_RS15435	COG0640	Transcriptional regulator
DUI70_RS15445	COG0517	IMP dehydrogenase activity
DUI70_RS15445	COG0516	GMP reductase activity
DUI70_RS15455	COG0589	response to stress
DUI70_RS15485	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DUI70_RS15525	COG4109	DRTGG domain
DUI70_RS15560	COG0725	ABC transporter, periplasmic molybdate-binding protein
DUI70_RS15580	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DUI70_RS15585	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DUI70_RS15590	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DUI70_RS15670	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS15675	COG0477	Major facilitator Superfamily
DUI70_RS15715	COG2815	serine threonine protein kinase
DUI70_RS15715	COG0515	serine threonine protein kinase
DUI70_RS15745	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS15750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DUI70_RS15755	COG4521	taurine ABC transporter
DUI70_RS15790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DUI70_RS15835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DUI70_RS15850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DUI70_RS15855	COG1309	transcriptional regulator
DUI70_RS15905	COG1131	(ABC) transporter
DUI70_RS15920	COG0494	nUDIX hydrolase
DUI70_RS15925	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DUI70_RS15930	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DUI70_RS15935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DUI70_RS15940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DUI70_RS15975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DUI70_RS15995	COG1120	ATPase activity
DUI70_RS16000	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DUI70_RS16005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DUI70_RS16010	COG1132	(ABC) transporter
DUI70_RS16030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DUI70_RS16040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS16045	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DUI70_RS16050	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DUI70_RS16070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DUI70_RS16085	COG1366	Belongs to the anti-sigma-factor antagonist family
DUI70_RS16090	COG1191	sigma factor activity
DUI70_RS16105	COG2208	phosphoserine phosphatase activity
DUI70_RS16105	COG2770	Histidine kinase
DUI70_RS16150	COG1073	alpha beta
DUI70_RS16165	COG0702	epimerase
DUI70_RS16195	COG1278	Cold shock
DUI70_RS16250	COG2326	polyphosphate kinase activity
DUI70_RS16290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DUI70_RS16290	COG1024	Enoyl-CoA hydratase
DUI70_RS16315	COG3629	intracellular signal transduction
DUI70_RS16355	COG0640	Transcriptional regulator
DUI70_RS16360	COG0346	lactoylglutathione lyase activity
DUI70_RS16365	COG3896	Chloramphenicol phosphotransferase-like protein
DUI70_RS16440	COG2197	response regulator
DUI70_RS16455	COG1733	regulation of RNA biosynthetic process
DUI70_RS16465	COG0702	epimerase
DUI70_RS16470	COG0747	negative chemotaxis
DUI70_RS16490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DUI70_RS16495	COG2755	lipolytic protein G-D-S-L family
DUI70_RS16505	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS16565	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DUI70_RS16570	COG2304	oxidoreductase activity
DUI70_RS16580	COG0583	DNA-binding transcription factor activity
DUI70_RS16590	COG2267	carboxylic ester hydrolase activity
DUI70_RS16595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DUI70_RS16625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DUI70_RS16635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DUI70_RS16680	COG0745	RESPONSE REGULATOR receiver
DUI70_RS16685	COG5002	protein histidine kinase activity
DUI70_RS16705	COG2186	Transcriptional regulator
DUI70_RS16765	COG1362	aminopeptidase activity
DUI70_RS16770	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS16785	COG1741	Belongs to the pirin family
DUI70_RS16810	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DUI70_RS16825	COG0508	dehydrogenase complex catalyzes the overall conversion of
DUI70_RS16830	COG0022	dehydrogenase e1 component
DUI70_RS16850	COG0515	serine threonine protein kinase
DUI70_RS16855	COG0515	serine threonine protein kinase
DUI70_RS16905	COG1522	sequence-specific DNA binding
DUI70_RS16910	COG1309	transcriptional regulator
DUI70_RS16915	COG1250	3-hydroxyacyl-CoA dehydrogenase
DUI70_RS16945	COG3396	Phenylacetate-CoA oxygenase
DUI70_RS16950	COG3460	Phenylacetate-CoA oxygenase
DUI70_RS16955	COG3396	Phenylacetate-CoA oxygenase
DUI70_RS16960	COG2151	metal-sulfur cluster biosynthetic enzyme
DUI70_RS16965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DUI70_RS16985	COG1733	regulation of RNA biosynthetic process
DUI70_RS16990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DUI70_RS17000	COG1716	ATPase activity
DUI70_RS17005	COG1716	ATPase activity
DUI70_RS17025	COG0515	serine threonine protein kinase
DUI70_RS17030	COG3764	Sortase (surface protein transpeptidase)
DUI70_RS17035	COG3764	Sortase (surface protein transpeptidase)
DUI70_RS17060	COG0705	Rhomboid family
DUI70_RS17060	COG0457	Tetratricopeptide repeat
DUI70_RS17085	COG0515	serine threonine protein kinase
DUI70_RS17105	COG2208	phosphoserine phosphatase activity
DUI70_RS17105	COG2172	sigma factor antagonist activity
DUI70_RS17105	COG1366	Belongs to the anti-sigma-factor antagonist family
DUI70_RS17115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DUI70_RS17135	COG1857	crispr-associated protein
DUI70_RS17190	COG2186	Transcriptional regulator
DUI70_RS17250	COG0582	viral genome integration into host DNA
DUI70_RS17265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DUI70_RS17270	COG0187	DNA topoisomerase II activity
DUI70_RS17275	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DUI70_RS17280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DUI70_RS17285	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DUI70_RS17290	COG0592	DNA-directed DNA polymerase activity
DUI70_RS17300	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DUI70_RS17305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DUI70_RS17310	COG0594	ribonuclease P activity
DUI70_RS17315	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DUI70_RS17320	COG0706	membrane insertase activity
DUI70_RS17330	COG0357	Ribosomal RNA small subunit methyltransferase G
DUI70_RS17335	COG1192	Involved in chromosome partitioning
DUI70_RS17350	COG3118	belongs to the thioredoxin family
DUI70_RS17355	COG0492	ferredoxin-NADP+ reductase activity
DUI70_RS17365	COG1595	DNA-templated transcription, initiation
DUI70_RS17370	COG0515	serine threonine protein kinase
DUI70_RS17370	COG2815	serine threonine protein kinase
DUI70_RS17385	COG0617	tRNA 3'-terminal CCA addition
DUI70_RS17410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DUI70_RS17435	COG0360	Binds together with S18 to 16S ribosomal RNA
DUI70_RS17440	COG0629	single-stranded DNA binding
DUI70_RS17445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DUI70_RS17450	COG0359	binds to the 23S rRNA
DUI70_RS17460	COG0305	Participates in initiation and elongation during chromosome replication
DUI70_RS17485	COG1535	isochorismatase
DUI70_RS17485	COG3433	isochorismatase activity
DUI70_RS17490	COG0393	Putative heavy-metal-binding
DUI70_RS17500	COG2318	DinB family
DUI70_RS17525	COG2814	Major facilitator Superfamily
DUI70_RS17545	COG0626	cystathionine gamma-synthase activity
DUI70_RS17550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DUI70_RS17555	COG1950	PFAM Membrane protein of
DUI70_RS17560	COG0662	Cupin 2, conserved barrel domain protein
DUI70_RS17585	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DUI70_RS17650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DUI70_RS17655	COG1609	Transcriptional regulator
DUI70_RS17660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DUI70_RS17665	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS17670	COG1271	oxidase subunit
DUI70_RS17675	COG1294	oxidase, subunit
DUI70_RS17680	COG4988	ABC transporter
DUI70_RS17690	COG0739	heme binding
DUI70_RS17700	COG0561	phosphatase activity
DUI70_RS17715	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DUI70_RS17735	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DUI70_RS17770	COG0561	phosphatase activity
DUI70_RS17775	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DUI70_RS17785	COG2837	iron assimilation
DUI70_RS17800	COG1999	signal sequence binding
DUI70_RS17840	COG0601	transmembrane transport
DUI70_RS17845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DUI70_RS17860	COG1940	carbohydrate kinase activity
DUI70_RS17880	COG0006	proline dipeptidase activity
DUI70_RS17895	COG0653	protein targeting
DUI70_RS17910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DUI70_RS17935	COG4129	membrane
DUI70_RS17950	COG1595	DNA-templated transcription, initiation
DUI70_RS17960	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS18070	COG2188	Transcriptional regulator
DUI70_RS18110	COG0745	RESPONSE REGULATOR receiver
DUI70_RS18115	COG2205	protein histidine kinase activity
DUI70_RS18125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DUI70_RS18125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DUI70_RS18140	COG2353	YceI-like domain
DUI70_RS18160	COG1191	sigma factor activity
DUI70_RS18165	COG1191	sigma factor activity
DUI70_RS18205	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DUI70_RS18235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS18245	COG0431	NADPH-dependent FMN reductase
DUI70_RS18255	COG0583	DNA-binding transcription factor activity
DUI70_RS18270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DUI70_RS18280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DUI70_RS18285	COG4948	Mandelate Racemase Muconate Lactonizing
DUI70_RS18305	COG0601	transmembrane transport
DUI70_RS18315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DUI70_RS18355	COG1136	(ABC) transporter
DUI70_RS18370	COG2318	DinB family
DUI70_RS18405	COG0640	Transcriptional regulator
DUI70_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS18420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS18430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DUI70_RS18475	COG1414	Transcriptional regulator
DUI70_RS18485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DUI70_RS18490	COG4948	Mandelate Racemase Muconate Lactonizing
DUI70_RS18500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DUI70_RS18505	COG0583	DNA-binding transcription factor activity
DUI70_RS18510	COG0697	spore germination
DUI70_RS18515	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DUI70_RS18535	COG0151	Belongs to the GarS family
DUI70_RS18565	COG2175	clavaminate synthase activity
DUI70_RS18585	COG0151	Belongs to the GarS family
DUI70_RS18600	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DUI70_RS18605	COG3119	arylsulfatase activity
DUI70_RS18610	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DUI70_RS18620	COG2197	response regulator
DUI70_RS18655	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DUI70_RS18660	COG0047	phosphoribosylformylglycinamidine synthase activity
DUI70_RS18665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DUI70_RS18670	COG2318	DinB family
DUI70_RS18675	COG1309	transcriptional regulator
DUI70_RS18705	COG3119	arylsulfatase activity
DUI70_RS18715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DUI70_RS18745	COG1643	Atp-dependent helicase
DUI70_RS18795	COG0513	Belongs to the DEAD box helicase family
DUI70_RS18800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS18815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DUI70_RS18820	COG1454	alcohol dehydrogenase
DUI70_RS18855	COG0515	serine threonine protein kinase
DUI70_RS18860	COG1216	Glycosyl transferase, family 2
DUI70_RS18860	COG0438	transferase activity, transferring glycosyl groups
DUI70_RS18930	COG2835	tetraacyldisaccharide 4'-kinase activity
DUI70_RS18950	COG4981	capsule polysaccharide biosynthetic process
DUI70_RS19005	COG0667	Aldo Keto reductase
DUI70_RS19015	COG2339	peptidase activity
DUI70_RS19025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DUI70_RS19030	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DUI70_RS19035	COG0579	oxidoreductase
DUI70_RS19065	COG0366	Alpha amylase catalytic
DUI70_RS19065	COG1470	cell adhesion involved in biofilm formation
DUI70_RS19075	COG1252	NADH dehydrogenase
DUI70_RS19180	COG0739	heme binding
DUI70_RS19180	COG0741	lytic transglycosylase activity
DUI70_RS19180	COG1196	nuclear chromosome segregation
DUI70_RS19185	COG0671	phosphoesterase, PA-phosphatase related
DUI70_RS19190	COG0277	FAD linked oxidase domain protein
DUI70_RS19210	COG1937	Protein conserved in bacteria
DUI70_RS19220	COG0306	phosphate transporter
DUI70_RS19225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DUI70_RS19240	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DUI70_RS19245	COG0406	alpha-ribazole phosphatase activity
DUI70_RS19245	COG0494	nUDIX hydrolase
DUI70_RS19255	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DUI70_RS19270	COG0456	acetyltransferase
DUI70_RS19280	COG0737	Belongs to the 5'-nucleotidase family
DUI70_RS19285	COG0823	Involved in the tonB-independent uptake of proteins
DUI70_RS19290	COG2205	protein histidine kinase activity
DUI70_RS19295	COG0745	RESPONSE REGULATOR receiver
DUI70_RS19300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DUI70_RS19310	COG1609	Transcriptional regulator
DUI70_RS19315	COG0745	RESPONSE REGULATOR receiver
DUI70_RS19345	COG2897	thiosulfate sulfurtransferase activity
DUI70_RS19370	COG3485	protocatechuate 3,4-dioxygenase
DUI70_RS19380	COG0354	folic acid binding
DUI70_RS19385	COG1490	D-aminoacyl-tRNA deacylase activity
DUI70_RS19400	COG4552	Acetyltransferase involved in intracellular survival and related
DUI70_RS19410	COG1309	transcriptional regulator
DUI70_RS19425	COG2188	Transcriptional regulator
DUI70_RS19480	COG2226	methyltransferase
DUI70_RS19520	COG0438	transferase activity, transferring glycosyl groups
DUI70_RS19560	COG0588	phosphoglycerate mutase activity
DUI70_RS19595	COG2124	cytochrome p450
DUI70_RS19610	COG5002	protein histidine kinase activity
DUI70_RS19630	COG1329	Transcriptional regulator
DUI70_RS19635	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DUI70_RS19640	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DUI70_RS19650	COG0215	cysteine-tRNA ligase activity
DUI70_RS19665	COG4585	Histidine kinase
DUI70_RS19670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DUI70_RS19680	COG3842	ATPase activity
DUI70_RS19690	COG3655	Transcriptional regulator
DUI70_RS19715	COG1366	Belongs to the anti-sigma-factor antagonist family
DUI70_RS19720	COG1366	Belongs to the anti-sigma-factor antagonist family
DUI70_RS19725	COG2172	sigma factor antagonist activity
DUI70_RS19735	COG2770	Histidine kinase
DUI70_RS19735	COG2208	phosphoserine phosphatase activity
DUI70_RS19755	COG2409	Drug exporters of the RND superfamily
DUI70_RS19775	COG2197	response regulator
DUI70_RS19780	COG1301	dicarboxylic acid transport
DUI70_RS19785	COG0745	RESPONSE REGULATOR receiver
DUI70_RS19805	COG1053	succinate dehydrogenase
DUI70_RS19810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DUI70_RS19870	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DUI70_RS19895	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DUI70_RS19930	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DUI70_RS19935	COG0463	Glycosyl transferase, family 2
DUI70_RS19950	COG1278	Cold shock
DUI70_RS19955	COG0459	protein refolding
DUI70_RS19975	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DUI70_RS20020	COG3973	AAA domain
DUI70_RS20035	COG1061	Type III restriction enzyme res subunit
DUI70_RS20055	COG3473	Maleate cis-trans isomerase
DUI70_RS20060	COG0179	Fumarylacetoacetate (FAA) hydrolase
DUI70_RS20080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DUI70_RS20100	COG0546	phosphoglycolate phosphatase activity
DUI70_RS20110	COG1278	Cold shock
DUI70_RS20115	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DUI70_RS20120	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DUI70_RS20130	COG2814	Major facilitator Superfamily
DUI70_RS20175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DUI70_RS20195	COG2252	PERMEase
DUI70_RS20220	COG0667	Aldo Keto reductase
DUI70_RS20240	COG1716	ATPase activity
DUI70_RS20240	COG1131	(ABC) transporter
DUI70_RS20240	COG0842	Transport permease protein
DUI70_RS20250	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DUI70_RS20255	COG0247	lactate metabolic process
DUI70_RS20255	COG0277	FAD linked oxidase domain protein
DUI70_RS20285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DUI70_RS20295	COG5006	permease, DMT superfamily
DUI70_RS20320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DUI70_RS20335	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS20340	COG1024	Enoyl-CoA hydratase
DUI70_RS20355	COG0259	pyridoxamine-phosphate oxidase activity
DUI70_RS20360	COG0596	Alpha beta hydrolase
DUI70_RS20370	COG4821	SIS domain
DUI70_RS20465	COG0488	(ABC) transporter
DUI70_RS20470	COG2072	flavoprotein involved in K transport
DUI70_RS20480	COG0259	pyridoxamine-phosphate oxidase activity
DUI70_RS20495	COG0515	serine threonine protein kinase
DUI70_RS20495	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DUI70_RS20520	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DUI70_RS20545	COG1686	Belongs to the peptidase S11 family
DUI70_RS20555	COG0386	Belongs to the glutathione peroxidase family
DUI70_RS20560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DUI70_RS20575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS20615	COG0454	-acetyltransferase
DUI70_RS20645	COG2986	histidine ammonia-lyase
DUI70_RS20675	COG3384	dioxygenase
DUI70_RS20680	COG1247	-acetyltransferase
DUI70_RS20695	COG1376	ErfK ybiS ycfS ynhG family protein
DUI70_RS20725	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DUI70_RS20740	COG3263	regulation of cellular component size
DUI70_RS20750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DUI70_RS20755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DUI70_RS20765	COG0315	cyclic pyranopterin monophosphate synthase activity
DUI70_RS20770	COG0521	Mo-molybdopterin cofactor biosynthetic process
DUI70_RS20770	COG0315	cyclic pyranopterin monophosphate synthase activity
DUI70_RS20775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DUI70_RS20790	COG3537	Alpha-1,2-mannosidase
DUI70_RS20825	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS20830	COG0477	Major facilitator Superfamily
DUI70_RS20845	COG0736	holo-[acyl-carrier-protein] synthase activity
DUI70_RS20875	COG4989	oxidoreductase activity
DUI70_RS20885	COG0708	Exodeoxyribonuclease III
DUI70_RS20895	COG2072	flavoprotein involved in K transport
DUI70_RS20900	COG2267	carboxylic ester hydrolase activity
DUI70_RS20905	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS20915	COG0793	Belongs to the peptidase S41A family
DUI70_RS20915	COG4946	Tricorn protease homolog
DUI70_RS20925	COG2409	Drug exporters of the RND superfamily
DUI70_RS20935	COG0310	cobalt ion transport
DUI70_RS20945	COG1122	ATPase activity
DUI70_RS20950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DUI70_RS20955	COG0789	Transcriptional regulator
DUI70_RS20980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DUI70_RS21010	COG0084	hydrolase, TatD family'
DUI70_RS21015	COG3583	domain protein
DUI70_RS21015	COG3584	3D domain protein
DUI70_RS21020	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DUI70_RS21025	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DUI70_RS21030	COG0488	(ABC) transporter
DUI70_RS21080	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DUI70_RS21090	COG2197	response regulator
DUI70_RS21100	COG4106	trans-aconitate 2-methyltransferase activity
DUI70_RS21110	COG1309	transcriptional regulator
DUI70_RS21120	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DUI70_RS21130	COG0193	aminoacyl-tRNA hydrolase activity
DUI70_RS21135	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DUI70_RS21140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DUI70_RS21145	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DUI70_RS21185	COG1316	TRANSCRIPTIONal
DUI70_RS21190	COG2814	Major facilitator Superfamily
DUI70_RS21195	COG1136	(ABC) transporter
DUI70_RS21200	COG0577	efflux transmembrane transporter activity
DUI70_RS21220	COG0561	phosphatase activity
DUI70_RS21230	COG0142	geranyltranstransferase activity
DUI70_RS21325	COG2234	aminopeptidase activity
DUI70_RS21325	COG4935	Belongs to the peptidase S8 family
DUI70_RS21335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DUI70_RS21340	COG0702	epimerase
DUI70_RS21355	COG1013	pyruvate-flavodoxin oxidoreductase activity
DUI70_RS21360	COG0674	pyruvate-flavodoxin oxidoreductase activity
DUI70_RS21360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DUI70_RS21380	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DUI70_RS21385	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DUI70_RS21395	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DUI70_RS21405	COG0839	Belongs to the complex I subunit 6 family
DUI70_RS21410	COG0713	ATP synthesis coupled electron transport
DUI70_RS21415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DUI70_RS21425	COG1007	ATP synthesis coupled electron transport
DUI70_RS21430	COG0501	Belongs to the peptidase M48B family
DUI70_RS21435	COG3304	Inner membrane component domain
DUI70_RS21445	COG2261	transglycosylase associated protein
DUI70_RS21455	COG1666	GTP binding
DUI70_RS21500	COG0702	epimerase
DUI70_RS21520	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DUI70_RS21525	COG2030	dehydratase
DUI70_RS21535	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DUI70_RS21540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DUI70_RS21545	COG0436	Aminotransferase
DUI70_RS21555	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DUI70_RS21560	COG0250	Participates in transcription elongation, termination and antitermination
DUI70_RS21570	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DUI70_RS21575	COG0081	regulation of translation
DUI70_RS21590	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DUI70_RS21595	COG0222	ribosome binding
DUI70_RS21605	COG0085	RNA polymerase activity
DUI70_RS21610	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DUI70_RS21650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DUI70_RS21655	COG0049	tRNA binding
DUI70_RS21660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DUI70_RS21665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DUI70_RS21670	COG0051	transcription antitermination factor activity, RNA binding
DUI70_RS21675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DUI70_RS21680	COG0088	Forms part of the polypeptide exit tunnel
DUI70_RS21685	COG0089	rRNA binding
DUI70_RS21690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DUI70_RS21695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DUI70_RS21700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DUI70_RS21705	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DUI70_RS21710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DUI70_RS21715	COG0255	Belongs to the universal ribosomal protein uL29 family
DUI70_RS21720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DUI70_RS21725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DUI70_RS21730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DUI70_RS21735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DUI70_RS21740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DUI70_RS21750	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DUI70_RS21755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DUI70_RS21760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DUI70_RS21765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DUI70_RS21775	COG0200	Binds to the 23S rRNA
DUI70_RS21785	COG0563	adenylate kinase activity
DUI70_RS21795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DUI70_RS21800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DUI70_RS21805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DUI70_RS21810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DUI70_RS21815	COG0202	RNA polymerase activity
DUI70_RS21820	COG0203	ribosomal protein L17
DUI70_RS21825	COG0101	tRNA pseudouridine synthase activity
DUI70_RS21835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DUI70_RS21840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DUI70_RS21845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DUI70_RS21855	COG1072	(Pantothenic acid kinase))
DUI70_RS21860	COG0736	holo-[acyl-carrier-protein] synthase activity
DUI70_RS21865	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DUI70_RS21865	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DUI70_RS21870	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DUI70_RS21880	COG0802	atpase or kinase
DUI70_RS21905	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DUI70_RS21925	COG4941	Belongs to the sigma-70 factor family
DUI70_RS21935	COG0726	polysaccharide deacetylase
DUI70_RS21945	COG0459	protein refolding
DUI70_RS21955	COG4221	oxidoreductase activity
DUI70_RS21965	COG0583	DNA-binding transcription factor activity
DUI70_RS21975	COG2197	response regulator
DUI70_RS21980	COG1595	DNA-templated transcription, initiation
DUI70_RS21995	COG0516	GMP reductase activity
DUI70_RS22005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DUI70_RS22025	COG2815	serine threonine protein kinase
DUI70_RS22025	COG0515	serine threonine protein kinase
DUI70_RS22040	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS22065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DUI70_RS22065	COG0519	Catalyzes the synthesis of GMP from XMP
DUI70_RS22115	COG2197	response regulator
DUI70_RS22125	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS22130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DUI70_RS22145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DUI70_RS22155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DUI70_RS22175	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS22190	COG0583	DNA-binding transcription factor activity
DUI70_RS22200	COG2197	response regulator
DUI70_RS22235	COG0739	heme binding
DUI70_RS22245	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DUI70_RS22260	COG0714	Associated with various cellular activities
DUI70_RS22270	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DUI70_RS22345	COG1222	aaa ATPase
DUI70_RS22375	COG0045	succinate-CoA ligase (ADP-forming) activity
DUI70_RS22410	COG0138	bifunctional purine biosynthesis protein purh
DUI70_RS22420	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DUI70_RS22435	COG1695	Transcriptional regulator
DUI70_RS22445	COG0039	L-malate dehydrogenase activity
DUI70_RS22470	COG3920	Histidine kinase
DUI70_RS22485	COG3119	arylsulfatase activity
DUI70_RS22490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DUI70_RS22495	COG1819	glycosyl
DUI70_RS22500	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DUI70_RS22505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DUI70_RS22510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DUI70_RS22515	COG0180	Tryptophanyl-tRNA synthetase
DUI70_RS22540	COG1295	ribonuclease BN
DUI70_RS22545	COG1686	Belongs to the peptidase S11 family
DUI70_RS22565	COG2409	Drug exporters of the RND superfamily
DUI70_RS22620	COG2009	succinate dehydrogenase
DUI70_RS22630	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DUI70_RS22665	COG1595	DNA-templated transcription, initiation
DUI70_RS22695	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DUI70_RS22705	COG1216	Glycosyl transferase, family 2
DUI70_RS22720	COG2089	acid synthase
DUI70_RS22730	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DUI70_RS22730	COG1473	amidohydrolase
DUI70_RS22735	COG1744	ABC transporter substrate-binding protein PnrA-like
DUI70_RS22740	COG3845	ABC transporter
DUI70_RS22745	COG4603	Belongs to the binding-protein-dependent transport system permease family
DUI70_RS22750	COG1079	Belongs to the binding-protein-dependent transport system permease family
DUI70_RS22790	COG2814	Major facilitator Superfamily
DUI70_RS22795	COG0583	DNA-binding transcription factor activity
DUI70_RS22805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DUI70_RS22830	COG2205	protein histidine kinase activity
DUI70_RS22835	COG0745	RESPONSE REGULATOR receiver
DUI70_RS22840	COG1595	DNA-templated transcription, initiation
DUI70_RS22855	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS22860	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS22880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DUI70_RS22905	COG4770	biotin carboxylase activity
DUI70_RS22915	COG0424	maF-like protein
DUI70_RS22925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DUI70_RS22935	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DUI70_RS22940	COG1024	Enoyl-CoA hydratase
DUI70_RS22950	COG0515	serine threonine protein kinase
DUI70_RS22960	COG1132	(ABC) transporter
DUI70_RS22965	COG1132	(ABC) transporter
DUI70_RS22980	COG2197	response regulator
DUI70_RS22985	COG2986	histidine ammonia-lyase
DUI70_RS23015	COG1064	alcohol dehydrogenase
DUI70_RS23035	COG0740	serine-type endopeptidase activity
DUI70_RS23040	COG0740	serine-type endopeptidase activity
DUI70_RS23065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DUI70_RS23095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DUI70_RS23110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DUI70_RS23120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DUI70_RS23130	COG3903	Transcriptional regulator
DUI70_RS23130	COG3629	intracellular signal transduction
DUI70_RS23135	COG0596	Alpha beta hydrolase
DUI70_RS23145	COG0667	Aldo Keto reductase
DUI70_RS23195	COG4249	Peptidase C14 caspase catalytic subunit p20
DUI70_RS23195	COG2319	Wd-40 repeat
DUI70_RS23205	COG2508	Transcriptional regulator
DUI70_RS23210	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS23215	COG0367	asparagine synthase
DUI70_RS23220	COG0477	Major facilitator Superfamily
DUI70_RS23225	COG2050	protein possibly involved in aromatic compounds catabolism
DUI70_RS23235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DUI70_RS23250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DUI70_RS23255	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS23280	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DUI70_RS23315	COG3629	intracellular signal transduction
DUI70_RS23315	COG3903	Transcriptional regulator
DUI70_RS23325	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS23360	COG3239	Fatty acid desaturase
DUI70_RS23365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DUI70_RS23370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DUI70_RS23375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DUI70_RS23385	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS23390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DUI70_RS23400	COG0243	molybdopterin cofactor binding
DUI70_RS23400	COG0243	molybdopterin cofactor binding
DUI70_RS23455	COG1331	Highly conserved protein containing a thioredoxin domain
DUI70_RS23470	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DUI70_RS23525	COG2894	cell division
DUI70_RS23565	COG2885	chlorophyll binding
DUI70_RS23605	COG1472	Belongs to the glycosyl hydrolase 3 family
DUI70_RS23610	COG2318	DinB family
DUI70_RS23625	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DUI70_RS23630	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DUI70_RS23660	COG1946	Acyl-CoA thioesterase
DUI70_RS23710	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS23735	COG1959	2 iron, 2 sulfur cluster binding
DUI70_RS23735	COG1295	ribonuclease BN
DUI70_RS23750	COG1472	Belongs to the glycosyl hydrolase 3 family
DUI70_RS23760	COG1609	Transcriptional regulator
DUI70_RS23765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DUI70_RS23805	COG3718	enzyme involved in inositol metabolism
DUI70_RS23810	COG3962	Belongs to the TPP enzyme family
DUI70_RS23830	COG1309	transcriptional regulator
DUI70_RS23835	COG1879	ABC-type sugar transport system periplasmic component
DUI70_RS23840	COG1129	ABC transporter
DUI70_RS23880	COG2755	lipolytic protein G-D-S-L family
DUI70_RS23895	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS23905	COG1309	transcriptional regulator
DUI70_RS23980	COG2205	protein histidine kinase activity
DUI70_RS24005	COG1309	transcriptional regulator
DUI70_RS24010	COG0745	RESPONSE REGULATOR receiver
DUI70_RS24015	COG5002	protein histidine kinase activity
DUI70_RS24030	COG0477	Major facilitator Superfamily
DUI70_RS24055	COG1819	glycosyl
DUI70_RS24060	COG1132	(ABC) transporter
DUI70_RS24065	COG2755	lipolytic protein G-D-S-L family
DUI70_RS24085	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DUI70_RS24085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS24090	COG2124	cytochrome p450
DUI70_RS24135	COG0367	asparagine synthase
DUI70_RS24145	COG2197	response regulator
DUI70_RS24195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DUI70_RS24235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DUI70_RS24260	COG0154	amidase activity
DUI70_RS24270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DUI70_RS24285	COG1595	DNA-templated transcription, initiation
DUI70_RS24330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DUI70_RS24355	COG0477	Major facilitator Superfamily
DUI70_RS24390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DUI70_RS24395	COG3938	Belongs to the proline racemase family
DUI70_RS24400	COG0531	amino acid
DUI70_RS24465	COG0702	epimerase
DUI70_RS24470	COG1733	regulation of RNA biosynthetic process
DUI70_RS24485	COG0515	serine threonine protein kinase
DUI70_RS24485	COG2815	serine threonine protein kinase
DUI70_RS24495	COG0494	nUDIX hydrolase
DUI70_RS24525	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DUI70_RS24535	COG1111	helicase
DUI70_RS24535	COG1205	dead DEAH box helicase
DUI70_RS24570	COG0629	single-stranded DNA binding
DUI70_RS24595	COG2346	COG2346, Truncated hemoglobins
DUI70_RS24600	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DUI70_RS24635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DUI70_RS24645	COG0668	transmembrane transport
DUI70_RS24700	COG0789	Transcriptional regulator
DUI70_RS24720	COG4941	Belongs to the sigma-70 factor family
DUI70_RS24725	COG3795	YCII-related domain
DUI70_RS24755	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DUI70_RS24760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DUI70_RS24765	COG1113	amino acid transport
DUI70_RS24770	COG1268	BioY protein
DUI70_RS24790	COG4552	Acetyltransferase involved in intracellular survival and related
DUI70_RS24805	COG3594	Acyltransferase
DUI70_RS24825	COG0544	peptidyl-prolyl cis-trans isomerase activity
DUI70_RS24830	COG0740	serine-type endopeptidase activity
DUI70_RS24835	COG0740	serine-type endopeptidase activity
DUI70_RS24840	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DUI70_RS24855	COG0525	valine-tRNA ligase activity
DUI70_RS24860	COG0285	dihydrofolate synthase activity
DUI70_RS24870	COG0105	UTP biosynthetic process
DUI70_RS24875	COG1077	Cell shape determining protein MreB Mrl
DUI70_RS24890	COG0768	penicillin binding
DUI70_RS24895	COG0772	Belongs to the SEDS family
DUI70_RS24925	COG1530	ribonuclease E activity
DUI70_RS24930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DUI70_RS24935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DUI70_RS24940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DUI70_RS24955	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DUI70_RS24965	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DUI70_RS24980	COG0501	Belongs to the peptidase M48B family
DUI70_RS24985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DUI70_RS24995	COG0799	negative regulation of ribosome biogenesis
DUI70_RS25000	COG0588	phosphoglycerate mutase activity
DUI70_RS25030	COG0495	leucyl-tRNA aminoacylation
DUI70_RS25040	COG1307	EDD domain protein, DegV family
DUI70_RS25055	COG1555	photosystem II stabilization
DUI70_RS25060	COG1234	tRNA 3'-trailer cleavage
DUI70_RS25080	COG0268	Binds directly to 16S ribosomal RNA
DUI70_RS25085	COG0481	GTPase activity
DUI70_RS25115	COG1420	regulation of RNA biosynthetic process
DUI70_RS25120	COG0484	heat shock protein binding
DUI70_RS25125	COG2070	2-Nitropropane dioxygenase
DUI70_RS25140	COG0793	Belongs to the peptidase S41A family
DUI70_RS25140	COG4946	Tricorn protease homolog
DUI70_RS25145	COG0537	adenosine 5'-monophosphoramidase activity
DUI70_RS25150	COG1234	tRNA 3'-trailer cleavage
DUI70_RS25155	COG0515	serine threonine protein kinase
DUI70_RS25155	COG2815	serine threonine protein kinase
DUI70_RS25165	COG1486	melibiose metabolic process
DUI70_RS25170	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DUI70_RS25170	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DUI70_RS25180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DUI70_RS25190	COG2315	Protein conserved in bacteria
DUI70_RS25215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DUI70_RS25235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DUI70_RS25245	COG2409	Drug exporters of the RND superfamily
DUI70_RS25250	COG4585	Histidine kinase
DUI70_RS25255	COG2197	response regulator
DUI70_RS25265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DUI70_RS25270	COG4608	Belongs to the ABC transporter superfamily
DUI70_RS25275	COG0444	Belongs to the ABC transporter superfamily
DUI70_RS25285	COG0747	negative chemotaxis
DUI70_RS25290	COG2186	Transcriptional regulator
DUI70_RS25300	COG1381	Involved in DNA repair and RecF pathway recombination
DUI70_RS25305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DUI70_RS25315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DUI70_RS25320	COG1121	(ABC) transporter
DUI70_RS25330	COG0423	glycine-tRNA ligase activity
DUI70_RS25340	COG2356	endonuclease I
DUI70_RS25350	COG0667	Aldo Keto reductase
DUI70_RS25355	COG0477	Major facilitator Superfamily
DUI70_RS25365	COG0477	Major facilitator Superfamily
DUI70_RS25390	COG1846	Transcriptional regulator
DUI70_RS25415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DUI70_RS25415	COG0574	Belongs to the PEP-utilizing enzyme family
DUI70_RS25430	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS25445	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS25450	COG1309	transcriptional regulator
DUI70_RS25460	COG2146	nitrite reductase [NAD(P)H] activity
DUI70_RS25460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DUI70_RS25465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DUI70_RS25495	COG0243	molybdopterin cofactor binding
DUI70_RS25500	COG2949	membrane
DUI70_RS25510	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DUI70_RS25520	COG0358	DNA primase activity
DUI70_RS25525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DUI70_RS25530	COG0515	serine threonine protein kinase
DUI70_RS25530	COG2815	serine threonine protein kinase
DUI70_RS25540	COG0384	phenazine biosynthesis protein PhzF
DUI70_RS25555	COG1070	Carbohydrate kinase
DUI70_RS25600	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS25645	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS25670	COG2130	NADP-dependent
DUI70_RS25680	COG3594	Acyltransferase
DUI70_RS25700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DUI70_RS25705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DUI70_RS25710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DUI70_RS25725	COG1741	Belongs to the pirin family
DUI70_RS25740	COG0789	Transcriptional regulator
DUI70_RS25745	COG0667	Aldo Keto reductase
DUI70_RS25760	COG1309	transcriptional regulator
DUI70_RS25765	COG0477	Major facilitator Superfamily
DUI70_RS25775	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DUI70_RS25820	COG1358	cellular component organization or biogenesis
DUI70_RS25830	COG0586	Pfam SNARE associated Golgi protein
DUI70_RS25835	COG4585	Histidine kinase
DUI70_RS25940	COG4122	O-methyltransferase activity
DUI70_RS25965	COG1127	ABC transporter
DUI70_RS25975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DUI70_RS26070	COG3845	ABC transporter
DUI70_RS26090	COG1309	transcriptional regulator
DUI70_RS26095	COG0438	transferase activity, transferring glycosyl groups
DUI70_RS26120	COG0860	N-Acetylmuramoyl-L-alanine amidase
DUI70_RS26130	COG0477	Major facilitator Superfamily
DUI70_RS26135	COG2197	response regulator
DUI70_RS26140	COG4585	Histidine kinase
DUI70_RS26145	COG2030	dehydratase
DUI70_RS26160	COG3321	synthase
DUI70_RS26160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS26165	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS26190	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DUI70_RS26215	COG3022	response to hydroperoxide
DUI70_RS26305	COG3540	Alkaline phosphatase
DUI70_RS26375	COG4221	oxidoreductase activity
DUI70_RS26385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DUI70_RS26395	COG1607	acyl-coa hydrolase
DUI70_RS26435	COG2814	Major facilitator Superfamily
DUI70_RS26440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DUI70_RS26480	COG0672	)-iron permease
DUI70_RS26485	COG2837	iron assimilation
DUI70_RS26495	COG1120	ATPase activity
DUI70_RS26500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DUI70_RS26505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DUI70_RS26525	COG5398	heme oxygenase
DUI70_RS26570	COG1994	Peptidase M50
DUI70_RS26590	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DUI70_RS26605	COG2814	Major facilitator Superfamily
DUI70_RS26610	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DUI70_RS26610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DUI70_RS26630	COG0174	glutamine synthetase
DUI70_RS26645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DUI70_RS26655	COG0367	asparagine synthase
DUI70_RS26675	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS26685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DUI70_RS26695	COG0366	Alpha amylase catalytic
DUI70_RS26705	COG2197	response regulator
DUI70_RS26720	COG0745	RESPONSE REGULATOR receiver
DUI70_RS26780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DUI70_RS26795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DUI70_RS26840	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DUI70_RS26845	COG0321	lipoyl(octanoyl) transferase activity
DUI70_RS26865	COG1090	epimerase
DUI70_RS26890	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DUI70_RS26900	COG0508	dehydrogenase complex catalyzes the overall conversion of
DUI70_RS26905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DUI70_RS26910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DUI70_RS26915	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DUI70_RS26920	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DUI70_RS26965	COG4585	Histidine kinase
DUI70_RS26970	COG2197	response regulator
DUI70_RS26975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DUI70_RS26990	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DUI70_RS27010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DUI70_RS27015	COG1104	cysteine desulfurase activity
DUI70_RS27020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DUI70_RS27025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DUI70_RS27035	COG1376	ErfK ybiS ycfS ynhG family protein
DUI70_RS27045	COG1845	cytochrome c oxidase, subunit III
DUI70_RS27050	COG2010	Cytochrome c
DUI70_RS27055	COG0723	plastoquinol--plastocyanin reductase activity
DUI70_RS27060	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DUI70_RS27065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DUI70_RS27070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DUI70_RS27100	COG0791	NLP P60 protein
DUI70_RS27100	COG0741	lytic transglycosylase activity
DUI70_RS27120	COG0438	transferase activity, transferring glycosyl groups
DUI70_RS27125	COG1022	Amp-dependent synthetase and ligase
DUI70_RS27140	COG0003	Pfam Anion-transporting ATPase
DUI70_RS27150	COG1940	carbohydrate kinase activity
DUI70_RS27175	COG4585	Histidine kinase
DUI70_RS27180	COG2197	response regulator
DUI70_RS27190	COG0205	6-phosphofructokinase activity
DUI70_RS27205	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DUI70_RS27210	COG0243	molybdopterin cofactor binding
DUI70_RS27215	COG2193	ferroxidase activity
DUI70_RS27220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DUI70_RS27225	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DUI70_RS27230	COG2815	serine threonine protein kinase
DUI70_RS27230	COG0515	serine threonine protein kinase
DUI70_RS27235	COG2022	thiamine diphosphate biosynthetic process
DUI70_RS27255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DUI70_RS27265	COG0352	thiamine-phosphate diphosphorylase activity
DUI70_RS27295	COG1309	transcriptional regulator
DUI70_RS27315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DUI70_RS27335	COG0714	Associated with various cellular activities
DUI70_RS27345	COG0275	rRNA processing
DUI70_RS27360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DUI70_RS27370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DUI70_RS27375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DUI70_RS27385	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DUI70_RS27400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DUI70_RS27415	COG1799	cell septum assembly
DUI70_RS27425	COG3599	regulation of cell shape
DUI70_RS27430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DUI70_RS27445	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DUI70_RS27505	COG0587	DNA-directed DNA polymerase activity
DUI70_RS27535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DUI70_RS27540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DUI70_RS27555	COG2197	response regulator
DUI70_RS27565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DUI70_RS27570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DUI70_RS27575	COG0131	Imidazoleglycerol-phosphate dehydratase
DUI70_RS27580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DUI70_RS27585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DUI70_RS27590	COG0251	oxidation-reduction process
DUI70_RS27595	COG0107	imidazoleglycerol-phosphate synthase activity
DUI70_RS27600	COG2409	Drug exporters of the RND superfamily
DUI70_RS27610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DUI70_RS27635	COG0134	indole-3-glycerol-phosphate synthase activity
DUI70_RS27645	COG0133	tryptophan synthase activity
DUI70_RS27650	COG0159	tryptophan synthase activity
DUI70_RS27660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DUI70_RS27665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DUI70_RS27675	COG0070	glutamate synthase
DUI70_RS27675	COG0069	glutamate synthase activity
DUI70_RS27675	COG0067	glutamate synthase
DUI70_RS27710	COG1470	cell adhesion involved in biofilm formation
DUI70_RS27710	COG0366	Alpha amylase catalytic
DUI70_RS27725	COG1605	Chorismate mutase
DUI70_RS27725	COG0287	Prephenate dehydrogenase
DUI70_RS27730	COG4566	intracellular signal transduction
DUI70_RS27810	COG2050	protein possibly involved in aromatic compounds catabolism
DUI70_RS27835	COG1643	Atp-dependent helicase
DUI70_RS27840	COG2226	methyltransferase
DUI70_RS27845	COG0539	negative regulation of cytoplasmic translation
DUI70_RS27865	COG0237	dephospho-CoA kinase activity
DUI70_RS27880	COG2226	methyltransferase
DUI70_RS27905	COG0277	FAD linked oxidase domain protein
DUI70_RS27965	COG0598	Magnesium transport protein CorA
DUI70_RS27970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DUI70_RS27975	COG2313	pseudouridylate synthase activity
DUI70_RS27980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DUI70_RS27985	COG0584	glycerophosphoryl diester phosphodiesterase
DUI70_RS27995	COG0556	nucleotide-excision repair
DUI70_RS28025	COG0387	Pfam Sodium calcium exchanger
DUI70_RS28030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DUI70_RS28045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DUI70_RS28055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DUI70_RS28060	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DUI70_RS28060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DUI70_RS28080	COG0322	excinuclease ABC activity
DUI70_RS28090	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DUI70_RS28095	COG1481	regulation of sporulation
DUI70_RS28100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DUI70_RS28105	COG0126	phosphoglycerate kinase activity
DUI70_RS28110	COG0149	triose-phosphate isomerase activity
DUI70_RS28115	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DUI70_RS28125	COG0166	Belongs to the GPI family
DUI70_RS28135	COG0363	glucosamine-6-phosphate deaminase activity
DUI70_RS28150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DUI70_RS28160	COG0109	protoheme IX farnesyltransferase activity
DUI70_RS28185	COG1131	(ABC) transporter
DUI70_RS28200	COG0719	Fe-S assembly protein
DUI70_RS28210	COG0396	ATPase activity
DUI70_RS28215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DUI70_RS28220	COG0822	iron-sulfur transferase activity
DUI70_RS28240	COG2076	Multidrug Resistance protein
DUI70_RS28245	COG2171	N-acyltransferase activity
DUI70_RS28260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DUI70_RS28305	COG2252	PERMEase
DUI70_RS28320	COG4977	sequence-specific DNA binding
DUI70_RS28330	COG5285	phytanoyl-CoA dioxygenase
DUI70_RS28335	COG1917	Cupin 2, conserved barrel domain protein
DUI70_RS28340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DUI70_RS28345	COG0456	acetyltransferase
DUI70_RS28350	COG1104	cysteine desulfurase activity
DUI70_RS28360	COG0765	amino acid transport
DUI70_RS28400	COG1797	cobyrinic acid a,c-diamide synthase activity
DUI70_RS28415	COG1492	cobalamin metabolic process
DUI70_RS28420	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DUI70_RS28440	COG0235	Class ii aldolase
DUI70_RS28460	COG0488	(ABC) transporter
DUI70_RS28520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DUI70_RS28535	COG1404	Belongs to the peptidase S8 family
DUI70_RS28550	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DUI70_RS28555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DUI70_RS28580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DUI70_RS28600	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DUI70_RS28610	COG2186	Transcriptional regulator
DUI70_RS28630	COG3830	Belongs to the UPF0237 family
DUI70_RS28630	COG0560	Phosphoserine phosphatase
DUI70_RS28635	COG1131	(ABC) transporter
DUI70_RS28635	COG0842	Transport permease protein
DUI70_RS28635	COG1716	ATPase activity
DUI70_RS28645	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DUI70_RS28650	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS28655	COG4585	Histidine kinase
DUI70_RS28660	COG2197	response regulator
DUI70_RS28670	COG1119	ATPase activity
DUI70_RS28690	COG1881	PFAM PEBP family protein
DUI70_RS28700	COG2094	Belongs to the DNA glycosylase MPG family
DUI70_RS28740	COG0647	UMP catabolic process
DUI70_RS28745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DUI70_RS28750	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DUI70_RS28775	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DUI70_RS28780	COG0497	DNA recombination
DUI70_RS28790	COG3387	PFAM Glycoside hydrolase 15-related
DUI70_RS28795	COG0504	CTP synthase activity
DUI70_RS28800	COG0494	nUDIX hydrolase
DUI70_RS28820	COG0686	Belongs to the AlaDH PNT family
DUI70_RS28840	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DUI70_RS28845	COG1187	pseudouridine synthase activity
DUI70_RS28885	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DUI70_RS28895	COG1160	GTP binding
DUI70_RS28910	COG0438	transferase activity, transferring glycosyl groups
DUI70_RS28935	COG0671	phosphoesterase, PA-phosphatase related
DUI70_RS28940	COG0477	Major facilitator Superfamily
DUI70_RS28945	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS28950	COG1799	cell septum assembly
DUI70_RS28965	COG0765	amino acid transport
DUI70_RS28975	COG1126	abc transporter atp-binding protein
DUI70_RS28980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS29005	COG0587	DNA-directed DNA polymerase activity
DUI70_RS29040	COG1725	Transcriptional regulator
DUI70_RS29050	COG2755	lipolytic protein G-D-S-L family
DUI70_RS29060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DUI70_RS29070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DUI70_RS29075	COG1879	ABC-type sugar transport system periplasmic component
DUI70_RS29080	COG1172	Belongs to the binding-protein-dependent transport system permease family
DUI70_RS29095	COG0395	ABC-type sugar transport system, permease component
DUI70_RS29100	COG1175	transmembrane transport
DUI70_RS29115	COG1609	Transcriptional regulator
DUI70_RS29135	COG1278	Cold shock
DUI70_RS29145	COG2188	Transcriptional regulator
DUI70_RS29150	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DUI70_RS29155	COG1309	transcriptional regulator
DUI70_RS29160	COG0243	molybdopterin cofactor binding
DUI70_RS29165	COG2851	Citrate transporter
DUI70_RS29210	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS29235	COG0789	Transcriptional regulator
DUI70_RS29245	COG3876	Protein conserved in bacteria
DUI70_RS29255	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS29275	COG2149	membrane
DUI70_RS29280	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DUI70_RS29310	COG3265	gluconokinase activity
DUI70_RS29315	COG2186	Transcriptional regulator
DUI70_RS29320	COG3012	SEC-C Motif Domain Protein
DUI70_RS29330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DUI70_RS29335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DUI70_RS29340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS29345	COG1953	Uracil, thiamine, allantoin
DUI70_RS29380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DUI70_RS29410	COG0667	Aldo Keto reductase
DUI70_RS29415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS29425	COG0598	Magnesium transport protein CorA
DUI70_RS29430	COG0406	alpha-ribazole phosphatase activity
DUI70_RS29445	COG0215	cysteine-tRNA ligase activity
DUI70_RS29450	COG1470	cell adhesion involved in biofilm formation
DUI70_RS29450	COG0366	Alpha amylase catalytic
DUI70_RS29465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DUI70_RS29470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DUI70_RS29475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DUI70_RS29480	COG1414	Transcriptional regulator
DUI70_RS29485	COG0646	methionine synthase
DUI70_RS29485	COG1410	methionine synthase
DUI70_RS29490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DUI70_RS29500	COG2197	response regulator
DUI70_RS29510	COG0517	IMP dehydrogenase activity
DUI70_RS29510	COG1994	Peptidase M50
DUI70_RS29530	COG1222	aaa ATPase
DUI70_RS29535	COG4122	O-methyltransferase activity
DUI70_RS29545	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DUI70_RS29550	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DUI70_RS29555	COG1609	Transcriptional regulator
DUI70_RS29565	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DUI70_RS29570	COG0545	Peptidyl-prolyl cis-trans isomerase
DUI70_RS29580	COG2378	regulation of single-species biofilm formation
DUI70_RS29600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DUI70_RS29605	COG0805	protein transport
DUI70_RS29655	COG0564	pseudouridine synthase activity
DUI70_RS29665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DUI70_RS29670	COG0517	IMP dehydrogenase activity
DUI70_RS29670	COG4175	Glycine betaine
DUI70_RS29685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DUI70_RS29705	COG0583	DNA-binding transcription factor activity
DUI70_RS29715	COG1309	transcriptional regulator
DUI70_RS29765	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DUI70_RS29770	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DUI70_RS29775	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DUI70_RS29780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DUI70_RS29785	COG5002	protein histidine kinase activity
DUI70_RS29790	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DUI70_RS29795	COG0072	phenylalanine-tRNA ligase activity
DUI70_RS29795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DUI70_RS29820	COG1649	PFAM Uncharacterised BCR, COG1649
DUI70_RS29830	COG0697	spore germination
DUI70_RS29845	COG2130	NADP-dependent
DUI70_RS29850	COG0789	Transcriptional regulator
DUI70_RS29860	COG0601	transmembrane transport
DUI70_RS29875	COG4106	trans-aconitate 2-methyltransferase activity
DUI70_RS29890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DUI70_RS29895	COG0346	lactoylglutathione lyase activity
DUI70_RS29905	COG2226	methyltransferase
DUI70_RS29935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DUI70_RS29945	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DUI70_RS29950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DUI70_RS29955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DUI70_RS29960	COG1438	arginine binding
DUI70_RS29965	COG0385	Bile acid
DUI70_RS29975	COG0277	FAD linked oxidase domain protein
DUI70_RS30000	COG3189	MarR family transcriptional regulator
DUI70_RS30005	COG0137	argininosuccinate synthase activity
DUI70_RS30010	COG0165	Argininosuccinate lyase
DUI70_RS30035	COG5650	phosphatidylinositol metabolic process
DUI70_RS30045	COG0204	Acyl-transferase
DUI70_RS30045	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS30065	COG3046	protein related to deoxyribodipyrimidine photolyase
DUI70_RS30080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DUI70_RS30085	COG2011	ABC-type metal ion transport system permease component
DUI70_RS30090	COG1464	Belongs to the NlpA lipoprotein family
DUI70_RS30105	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DUI70_RS30110	COG1648	precorrin-2 dehydrogenase activity
DUI70_RS30110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DUI70_RS30140	COG2233	PERMEase
DUI70_RS30150	COG0477	Major facilitator Superfamily
DUI70_RS30185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DUI70_RS30250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DUI70_RS30270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DUI70_RS30275	COG1560	Kdo2-lipid A biosynthetic process
DUI70_RS30280	COG0438	transferase activity, transferring glycosyl groups
DUI70_RS30290	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DUI70_RS30295	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DUI70_RS30300	COG0217	transcriptional regulatory protein
DUI70_RS30305	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DUI70_RS30310	COG0632	four-way junction helicase activity
DUI70_RS30315	COG2255	four-way junction helicase activity
DUI70_RS30325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DUI70_RS30330	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DUI70_RS30335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DUI70_RS30345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DUI70_RS30365	COG1196	nuclear chromosome segregation
DUI70_RS30370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DUI70_RS30380	COG0124	histidyl-tRNA synthetase
DUI70_RS30395	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DUI70_RS30410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DUI70_RS30415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DUI70_RS30425	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DUI70_RS30430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DUI70_RS30435	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DUI70_RS30440	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DUI70_RS30450	COG0006	proline dipeptidase activity
DUI70_RS30455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DUI70_RS30460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DUI70_RS30470	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DUI70_RS30475	COG0540	Belongs to the ATCase OTCase family
DUI70_RS30480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DUI70_RS30490	COG0505	Belongs to the CarA family
DUI70_RS30495	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DUI70_RS30500	COG0167	dihydroorotate dehydrogenase activity
DUI70_RS30505	COG0284	orotidine-5'-phosphate decarboxylase activity
DUI70_RS30515	COG0194	GDP metabolic process
DUI70_RS30520	COG1758	RNA polymerase activity
DUI70_RS30530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DUI70_RS30550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DUI70_RS30575	COG2409	Drug exporters of the RND superfamily
DUI70_RS30580	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DUI70_RS30585	COG2390	Transcriptional regulator
DUI70_RS30605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DUI70_RS30635	COG0702	epimerase
DUI70_RS30650	COG3201	nicotinamide mononucleotide transporter
DUI70_RS30655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DUI70_RS30655	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DUI70_RS30660	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DUI70_RS30665	COG0140	phosphoribosyl-ATP diphosphatase activity
DUI70_RS30670	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DUI70_RS30725	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS30740	COG1522	sequence-specific DNA binding
DUI70_RS30750	COG0463	Glycosyl transferase, family 2
DUI70_RS30765	COG0584	glycerophosphoryl diester phosphodiesterase
DUI70_RS30775	COG2186	Transcriptional regulator
DUI70_RS30810	COG0438	transferase activity, transferring glycosyl groups
DUI70_RS30815	COG1984	allophanate hydrolase subunit 2
DUI70_RS30820	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DUI70_RS30825	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DUI70_RS30830	COG4336	lyase activity
DUI70_RS30835	COG2814	Major facilitator Superfamily
DUI70_RS30870	COG2018	Roadblock/LC7 domain
DUI70_RS30890	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DUI70_RS30905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DUI70_RS30915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DUI70_RS30920	COG2190	(PTS) system
DUI70_RS30945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DUI70_RS30965	COG1716	ATPase activity
DUI70_RS30985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DUI70_RS30995	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DUI70_RS30995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DUI70_RS31065	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DUI70_RS31070	COG0531	amino acid
DUI70_RS31080	COG0174	glutamine synthetase
DUI70_RS31085	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS31095	COG0697	spore germination
DUI70_RS31135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DUI70_RS31150	COG0673	inositol 2-dehydrogenase activity
DUI70_RS31155	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DUI70_RS31175	COG1968	undecaprenyl-diphosphatase activity
DUI70_RS31220	COG0110	maltose O-acetyltransferase activity
DUI70_RS31235	COG1832	CoA-binding protein
DUI70_RS31240	COG1739	Uncharacterized protein family UPF0029
DUI70_RS31250	COG0436	Aminotransferase
DUI70_RS31260	COG0420	3'-5' exonuclease activity
DUI70_RS31265	COG0419	ATPase involved in DNA repair
DUI70_RS31280	COG0626	cystathionine gamma-synthase activity
DUI70_RS31295	COG0346	lactoylglutathione lyase activity
DUI70_RS31315	COG2197	response regulator
DUI70_RS31330	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DUI70_RS31370	COG2723	6-phospho-beta-galactosidase activity
DUI70_RS31375	COG0395	ABC-type sugar transport system, permease component
DUI70_RS31380	COG1175	transmembrane transport
DUI70_RS31385	COG2182	Extracellular solute-binding protein
DUI70_RS31390	COG1940	carbohydrate kinase activity
DUI70_RS31410	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DUI70_RS31415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DUI70_RS31420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DUI70_RS31435	COG0791	NLP P60 protein
DUI70_RS31445	COG1309	transcriptional regulator
DUI70_RS31460	COG2018	Roadblock/LC7 domain
DUI70_RS31470	COG1946	Acyl-CoA thioesterase
DUI70_RS31485	COG1132	(ABC) transporter
DUI70_RS31505	COG1132	(ABC) transporter
DUI70_RS31515	COG2072	flavoprotein involved in K transport
DUI70_RS31520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS31530	COG1116	anion transmembrane transporter activity
DUI70_RS31535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DUI70_RS31540	COG0432	Pfam Uncharacterised protein family UPF0047
DUI70_RS31575	COG1408	metallophosphoesterase
DUI70_RS31580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DUI70_RS31620	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DUI70_RS31705	COG1793	dna ligase
DUI70_RS31705	COG3285	dna ligase
DUI70_RS31740	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS31750	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DUI70_RS31780	COG2610	gluconate transmembrane transporter activity
DUI70_RS31785	COG0251	oxidation-reduction process
DUI70_RS31790	COG1414	Transcriptional regulator
DUI70_RS31810	COG3469	chitinase activity
DUI70_RS31835	COG3467	pyridoxamine 5'-phosphate
DUI70_RS31840	COG3387	PFAM Glycoside hydrolase 15-related
DUI70_RS31885	COG3845	ABC transporter
DUI70_RS31905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DUI70_RS31915	COG3290	protein histidine kinase activity
DUI70_RS31955	COG0375	protein maturation
DUI70_RS31960	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DUI70_RS31975	COG0409	Hydrogenase expression formation protein
DUI70_RS31980	COG0309	Hydrogenase expression formation protein (HypE)
DUI70_RS32010	COG1024	Enoyl-CoA hydratase
DUI70_RS32040	COG0667	Aldo Keto reductase
DUI70_RS32050	COG1595	DNA-templated transcription, initiation
DUI70_RS32080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DUI70_RS32085	COG2040	homocysteine
DUI70_RS32095	COG1902	pentaerythritol trinitrate reductase activity
DUI70_RS32100	COG0640	Transcriptional regulator
DUI70_RS32110	COG1309	transcriptional regulator
DUI70_RS32120	COG0546	phosphoglycolate phosphatase activity
DUI70_RS32125	COG0671	phosphoesterase, PA-phosphatase related
DUI70_RS32140	COG1024	Enoyl-CoA hydratase
DUI70_RS32150	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DUI70_RS32190	COG1134	teichoic acid transport
DUI70_RS32205	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DUI70_RS32215	COG1657	PFAM Prenyltransferase squalene oxidase
DUI70_RS32235	COG2365	Tyrosine phosphatase family
DUI70_RS32245	COG2755	lipolytic protein G-D-S-L family
DUI70_RS32280	COG1063	alcohol dehydrogenase
DUI70_RS32290	COG0583	DNA-binding transcription factor activity
DUI70_RS32330	COG0183	Belongs to the thiolase family
DUI70_RS32390	COG0778	Nitroreductase
DUI70_RS32445	COG0720	synthase
DUI70_RS32505	COG1127	ABC transporter
DUI70_RS32555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DUI70_RS32580	COG0633	Ferredoxin
DUI70_RS32595	COG2197	response regulator
DUI70_RS32600	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS32605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS32615	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS32630	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS32675	COG3971	2-oxopent-4-enoate hydratase activity
DUI70_RS32695	COG0633	Ferredoxin
DUI70_RS32700	COG2197	response regulator
DUI70_RS32710	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DUI70_RS32725	COG0604	alcohol dehydrogenase
DUI70_RS32730	COG1024	Enoyl-CoA hydratase
DUI70_RS32735	COG2186	Transcriptional regulator
DUI70_RS32740	COG0183	Belongs to the thiolase family
DUI70_RS32745	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DUI70_RS32745	COG1703	isobutyryl-CoA mutase activity
DUI70_RS32745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DUI70_RS32750	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DUI70_RS32760	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS32770	COG2030	dehydratase
DUI70_RS32775	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS32780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DUI70_RS32785	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS32795	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS32800	COG0183	Belongs to the thiolase family
DUI70_RS32805	COG0427	acetyl-CoA hydrolase
DUI70_RS32810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DUI70_RS32815	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS32860	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS32880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DUI70_RS32925	COG4106	trans-aconitate 2-methyltransferase activity
DUI70_RS32935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DUI70_RS32940	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS32950	COG1132	(ABC) transporter
DUI70_RS32955	COG2814	Major facilitator Superfamily
DUI70_RS32995	COG0640	Transcriptional regulator
DUI70_RS33015	COG1309	transcriptional regulator
DUI70_RS33045	COG5322	oxidoreductase activity
DUI70_RS33045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DUI70_RS33050	COG3321	synthase
DUI70_RS33050	COG0604	alcohol dehydrogenase
DUI70_RS33065	COG0318	PFAM AMP-dependent synthetase and ligase
DUI70_RS33090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DUI70_RS33095	COG0475	glutathione-regulated potassium exporter activity
DUI70_RS33110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DUI70_RS33115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS33130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS33130	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DUI70_RS33135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DUI70_RS33150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DUI70_RS33305	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DUI70_RS33320	COG0714	Associated with various cellular activities
DUI70_RS33345	COG0454	-acetyltransferase
DUI70_RS33470	COG0151	Belongs to the GarS family
DUI70_RS33550	COG1028	Short-chain dehydrogenase reductase Sdr
DUI70_RS33595	COG4221	oxidoreductase activity
DUI70_RS33605	COG0339	signal peptide processing
DUI70_RS33635	COG0667	Aldo Keto reductase
DUI70_RS33720	COG0494	nUDIX hydrolase
DUI70_RS33730	COG0105	UTP biosynthetic process
DUI70_RS33760	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DUI70_RS33785	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DUI70_RS33805	COG3458	cephalosporin-C deacetylase activity
DUI70_RS33845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DUI70_RS33900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DUI70_RS33915	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DUI70_RS33920	COG0121	glutamine amidotransferase
DUI70_RS33925	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DUI70_RS33940	COG1609	Transcriptional regulator
DUI70_RS33945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DUI70_RS33955	COG2813	Specifically methylates the guanine in position
DUI70_RS33975	COG1289	transmembrane transporter activity
DUI70_RS33985	COG2837	iron assimilation
DUI70_RS33990	COG0076	glutamate decarboxylase activity
DUI70_RS33995	COG0542	response to heat
DUI70_RS34015	COG0477	Major facilitator Superfamily
DUI70_RS34060	COG0395	ABC-type sugar transport system, permease component
DUI70_RS34065	COG1175	transmembrane transport
DUI70_RS34075	COG3250	beta-galactosidase activity
DUI70_RS34080	COG1609	Transcriptional regulator
DUI70_RS34090	COG3290	protein histidine kinase activity
DUI70_RS34100	COG1940	carbohydrate kinase activity
DUI70_RS34105	COG1309	transcriptional regulator
DUI70_RS34140	COG1175	transmembrane transport
DUI70_RS34160	COG1113	amino acid transport
DUI70_RS34170	COG1174	glycine betaine transport
DUI70_RS34175	COG1174	glycine betaine transport
DUI70_RS34200	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DUI70_RS34200	COG3291	Pkd domain containing protein
DUI70_RS34230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DUI70_RS34240	COG0019	diaminopimelate decarboxylase activity
DUI70_RS34280	COG0596	Alpha beta hydrolase
DUI70_RS34290	COG0204	Acyl-transferase
DUI70_RS34305	COG0205	6-phosphofructokinase activity
DUI70_RS34310	COG3442	glutamine amidotransferase
DUI70_RS34320	COG0242	peptide deformylase activity
DUI70_RS34330	COG1960	acyl-CoA dehydrogenase activity
DUI70_RS34335	COG1012	belongs to the aldehyde dehydrogenase family
DUI70_RS34345	COG1793	dna ligase
DUI70_RS34355	COG1335	isochorismatase
DUI70_RS34400	COG1595	DNA-templated transcription, initiation
DUI70_RS34415	COG0477	Major facilitator Superfamily
DUI70_RS34425	COG0242	peptide deformylase activity
DUI70_RS34445	COG0309	Hydrogenase expression formation protein (HypE)
DUI70_RS34450	COG0604	alcohol dehydrogenase