locus-tag	class	description
G9272_RS00140	COG1522	sequence-specific DNA binding
G9272_RS00155	COG0254	rRNA binding
G9272_RS00160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G9272_RS00165	COG2814	Major facilitator Superfamily
G9272_RS00170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G9272_RS00175	COG0456	acetyltransferase
G9272_RS00225	COG0778	Nitroreductase
G9272_RS00235	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G9272_RS00265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G9272_RS00275	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G9272_RS00280	COG0477	Major facilitator Superfamily
G9272_RS00285	COG2132	Multicopper oxidase
G9272_RS00295	COG4249	Peptidase C14 caspase catalytic subunit p20
G9272_RS00295	COG2319	Wd-40 repeat
G9272_RS00310	COG2124	cytochrome p450
G9272_RS00315	COG2226	methyltransferase
G9272_RS00315	COG2867	negative regulation of translational initiation
G9272_RS00345	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9272_RS00355	COG2124	cytochrome p450
G9272_RS00420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G9272_RS00440	COG3425	synthase
G9272_RS00495	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G9272_RS00505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9272_RS00510	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G9272_RS00550	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS00555	COG0655	NAD(P)H dehydrogenase (quinone) activity
G9272_RS00565	COG2345	Transcriptional regulator
G9272_RS00570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G9272_RS00580	COG3424	synthase
G9272_RS00590	COG3903	Transcriptional regulator
G9272_RS00590	COG3629	intracellular signal transduction
G9272_RS00620	COG0702	epimerase
G9272_RS00640	COG0247	lactate metabolic process
G9272_RS00640	COG2181	nitrate reductase activity
G9272_RS00660	COG0501	Belongs to the peptidase M48B family
G9272_RS00705	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS00750	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G9272_RS00830	COG0583	DNA-binding transcription factor activity
G9272_RS00925	COG2175	clavaminate synthase activity
G9272_RS00955	COG0604	alcohol dehydrogenase
G9272_RS00955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9272_RS00955	COG3321	synthase
G9272_RS00955	COG4221	oxidoreductase activity
G9272_RS00970	COG5640	endopeptidase activity
G9272_RS01020	COG2267	carboxylic ester hydrolase activity
G9272_RS01030	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G9272_RS01045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9272_RS01065	COG0076	glutamate decarboxylase activity
G9272_RS01070	COG3424	synthase
G9272_RS01090	COG0667	Aldo Keto reductase
G9272_RS01095	COG1309	transcriptional regulator
G9272_RS01155	COG0596	Alpha beta hydrolase
G9272_RS01160	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS01210	COG3293	Transposase
G9272_RS01245	COG0667	Aldo Keto reductase
G9272_RS01250	COG1309	transcriptional regulator
G9272_RS01265	COG2814	Major facilitator Superfamily
G9272_RS01345	COG1902	pentaerythritol trinitrate reductase activity
G9272_RS01350	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS01360	COG0657	acetylesterase activity
G9272_RS01425	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS01430	COG0673	inositol 2-dehydrogenase activity
G9272_RS01435	COG0673	inositol 2-dehydrogenase activity
G9272_RS01440	COG0673	inositol 2-dehydrogenase activity
G9272_RS01460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9272_RS01470	COG3718	enzyme involved in inositol metabolism
G9272_RS01480	COG2188	Transcriptional regulator
G9272_RS01490	COG1082	Xylose isomerase domain protein TIM barrel
G9272_RS01495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G9272_RS01500	COG0673	inositol 2-dehydrogenase activity
G9272_RS01510	COG3962	Belongs to the TPP enzyme family
G9272_RS01515	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS01590	COG0778	Nitroreductase
G9272_RS01605	COG1063	alcohol dehydrogenase
G9272_RS01610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G9272_RS01610	COG2124	cytochrome p450
G9272_RS01635	COG0640	Transcriptional regulator
G9272_RS01645	COG2226	methyltransferase
G9272_RS01670	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G9272_RS01690	COG1131	(ABC) transporter
G9272_RS01700	COG1595	DNA-templated transcription, initiation
G9272_RS01705	COG3408	Glycogen debranching enzyme
G9272_RS01730	COG0583	DNA-binding transcription factor activity
G9272_RS01750	COG1609	Transcriptional regulator
G9272_RS01785	COG0702	epimerase
G9272_RS01795	COG2080	2 iron, 2 sulfur cluster binding
G9272_RS01800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G9272_RS01805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G9272_RS01845	COG3507	Belongs to the glycosyl hydrolase 43 family
G9272_RS01860	COG1609	Transcriptional regulator
G9272_RS01900	COG3321	synthase
G9272_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS01900	COG0604	alcohol dehydrogenase
G9272_RS01905	COG1309	transcriptional regulator
G9272_RS01915	COG3507	Belongs to the glycosyl hydrolase 43 family
G9272_RS01930	COG3250	beta-galactosidase activity
G9272_RS01950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G9272_RS02025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G9272_RS02045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9272_RS02060	COG0583	DNA-binding transcription factor activity
G9272_RS02075	COG2226	methyltransferase
G9272_RS02125	COG1278	Cold shock
G9272_RS02130	COG0069	glutamate synthase activity
G9272_RS02135	COG0028	Belongs to the TPP enzyme family
G9272_RS02175	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G9272_RS02185	COG2261	transglycosylase associated protein
G9272_RS02200	COG1960	acyl-CoA dehydrogenase activity
G9272_RS02210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G9272_RS02220	COG0477	Major facilitator Superfamily
G9272_RS02250	COG1280	lysine exporter protein (LysE YggA)
G9272_RS02265	COG2226	methyltransferase
G9272_RS02320	COG2814	Major facilitator Superfamily
G9272_RS02350	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G9272_RS02365	COG0604	alcohol dehydrogenase
G9272_RS02375	COG1309	transcriptional regulator
G9272_RS02380	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS02415	COG0367	asparagine synthase
G9272_RS02420	COG2308	Evidence 4 Homologs of previously reported genes of
G9272_RS02420	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G9272_RS02460	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS02465	COG0183	Belongs to the thiolase family
G9272_RS02470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G9272_RS02475	COG0183	Belongs to the thiolase family
G9272_RS02485	COG1960	acyl-CoA dehydrogenase activity
G9272_RS02500	COG2188	Transcriptional regulator
G9272_RS02515	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS02530	COG1024	Enoyl-CoA hydratase
G9272_RS02540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G9272_RS02545	COG0300	oxidoreductase activity
G9272_RS02555	COG1960	acyl-CoA dehydrogenase activity
G9272_RS02560	COG1960	acyl-CoA dehydrogenase activity
G9272_RS02565	COG1024	Enoyl-CoA hydratase
G9272_RS02580	COG1024	Enoyl-CoA hydratase
G9272_RS02590	COG1960	acyl-CoA dehydrogenase activity
G9272_RS02620	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS02625	COG1960	acyl-CoA dehydrogenase activity
G9272_RS02630	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS02635	COG1024	Enoyl-CoA hydratase
G9272_RS02640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G9272_RS02645	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS02655	COG1960	acyl-CoA dehydrogenase activity
G9272_RS02660	COG1960	acyl-CoA dehydrogenase activity
G9272_RS02665	COG1960	acyl-CoA dehydrogenase activity
G9272_RS02680	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS02705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS02715	COG1960	acyl-CoA dehydrogenase activity
G9272_RS02725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G9272_RS02735	COG0640	Transcriptional regulator
G9272_RS02745	COG0515	serine threonine protein kinase
G9272_RS02790	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G9272_RS02795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G9272_RS02810	COG4176	ABC-type proline glycine betaine transport system permease component
G9272_RS02815	COG4175	Glycine betaine
G9272_RS02815	COG0517	IMP dehydrogenase activity
G9272_RS02820	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS02835	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G9272_RS02885	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS02910	COG2124	cytochrome p450
G9272_RS02930	COG0251	oxidation-reduction process
G9272_RS02935	COG0583	DNA-binding transcription factor activity
G9272_RS02955	COG4977	sequence-specific DNA binding
G9272_RS02965	COG3387	PFAM Glycoside hydrolase 15-related
G9272_RS02990	COG2340	Cysteine-rich secretory protein family
G9272_RS03005	COG1309	transcriptional regulator
G9272_RS03010	COG0604	alcohol dehydrogenase
G9272_RS03010	COG3321	synthase
G9272_RS03015	COG0604	alcohol dehydrogenase
G9272_RS03015	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS03015	COG3321	synthase
G9272_RS03025	COG4821	SIS domain
G9272_RS03030	COG1737	Transcriptional regulator
G9272_RS03050	COG1175	transmembrane transport
G9272_RS03055	COG0395	ABC-type sugar transport system, permease component
G9272_RS03060	COG1472	Belongs to the glycosyl hydrolase 3 family
G9272_RS03075	COG1472	Belongs to the glycosyl hydrolase 3 family
G9272_RS03090	COG0477	Major facilitator Superfamily
G9272_RS03120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G9272_RS03125	COG5002	protein histidine kinase activity
G9272_RS03130	COG0745	RESPONSE REGULATOR receiver
G9272_RS03150	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G9272_RS03160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS03170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G9272_RS03180	COG1295	ribonuclease BN
G9272_RS03230	COG2207	Transcriptional regulator
G9272_RS03280	COG1595	DNA-templated transcription, initiation
G9272_RS03300	COG0366	Alpha amylase catalytic
G9272_RS03300	COG1874	Beta-galactosidase
G9272_RS03345	COG1609	Transcriptional regulator
G9272_RS03355	COG0395	ABC-type sugar transport system, permease component
G9272_RS03360	COG4209	transmembrane transport
G9272_RS03370	COG1609	Transcriptional regulator
G9272_RS03380	COG1175	transmembrane transport
G9272_RS03385	COG0395	ABC-type sugar transport system, permease component
G9272_RS03445	COG2124	cytochrome p450
G9272_RS03460	COG1309	transcriptional regulator
G9272_RS03465	COG0009	L-threonylcarbamoyladenylate synthase
G9272_RS03485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G9272_RS03500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS03520	COG0656	L-ascorbic acid biosynthetic process
G9272_RS03550	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9272_RS03555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9272_RS03560	COG2382	esterase
G9272_RS03565	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G9272_RS03570	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS03575	COG1169	isochorismate synthase
G9272_RS03580	COG1021	2,3-dihydroxybenzoate-AMP ligase
G9272_RS03590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9272_RS03595	COG2382	esterase
G9272_RS03610	COG0745	RESPONSE REGULATOR receiver
G9272_RS03630	COG4585	Histidine kinase
G9272_RS03635	COG4585	Histidine kinase
G9272_RS03640	COG2197	response regulator
G9272_RS03645	COG1793	dna ligase
G9272_RS03665	COG0181	hydroxymethylbilane synthase activity
G9272_RS03675	COG0842	Transport permease protein
G9272_RS03685	COG1846	Transcriptional regulator
G9272_RS03715	COG0366	Alpha amylase catalytic
G9272_RS03730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G9272_RS03735	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G9272_RS03760	COG1191	sigma factor activity
G9272_RS03765	COG5002	protein histidine kinase activity
G9272_RS03765	COG2205	protein histidine kinase activity
G9272_RS03765	COG0784	Response regulator, receiver
G9272_RS03790	COG1366	Belongs to the anti-sigma-factor antagonist family
G9272_RS03795	COG1366	Belongs to the anti-sigma-factor antagonist family
G9272_RS03800	COG2172	sigma factor antagonist activity
G9272_RS03865	COG0477	Major facilitator Superfamily
G9272_RS03875	COG0583	DNA-binding transcription factor activity
G9272_RS03895	COG5002	protein histidine kinase activity
G9272_RS03940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G9272_RS03975	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G9272_RS03975	COG1672	PFAM Archaeal ATPase
G9272_RS03995	COG0142	geranyltranstransferase activity
G9272_RS04000	COG0515	serine threonine protein kinase
G9272_RS04000	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9272_RS04010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS04025	COG0667	Aldo Keto reductase
G9272_RS04065	COG0328	RNA-DNA hybrid ribonuclease activity
G9272_RS04075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G9272_RS04085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G9272_RS04100	COG0596	Alpha beta hydrolase
G9272_RS04105	COG0740	serine-type endopeptidase activity
G9272_RS04110	COG0740	serine-type endopeptidase activity
G9272_RS04115	COG1396	sequence-specific DNA binding
G9272_RS04120	COG1191	sigma factor activity
G9272_RS04150	COG1131	(ABC) transporter
G9272_RS04150	COG0842	Transport permease protein
G9272_RS04150	COG1716	ATPase activity
G9272_RS04170	COG0667	Aldo Keto reductase
G9272_RS04175	COG0583	DNA-binding transcription factor activity
G9272_RS04185	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G9272_RS04190	COG0346	lactoylglutathione lyase activity
G9272_RS04200	COG0667	Aldo Keto reductase
G9272_RS04220	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS04225	COG4941	Belongs to the sigma-70 factor family
G9272_RS04250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS04260	COG0431	NADPH-dependent FMN reductase
G9272_RS04270	COG0583	DNA-binding transcription factor activity
G9272_RS04280	COG2409	Drug exporters of the RND superfamily
G9272_RS04285	COG1846	Transcriptional regulator
G9272_RS04320	COG1595	DNA-templated transcription, initiation
G9272_RS04335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G9272_RS04340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G9272_RS04410	COG0069	glutamate synthase activity
G9272_RS04415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G9272_RS04425	COG0673	inositol 2-dehydrogenase activity
G9272_RS04480	COG1024	Enoyl-CoA hydratase
G9272_RS04505	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS04515	COG2070	2-Nitropropane dioxygenase
G9272_RS04545	COG0515	serine threonine protein kinase
G9272_RS04575	COG0709	Synthesizes selenophosphate from selenide and ATP
G9272_RS04605	COG1309	transcriptional regulator
G9272_RS04615	COG2267	carboxylic ester hydrolase activity
G9272_RS04620	COG1309	transcriptional regulator
G9272_RS04635	COG0574	Belongs to the PEP-utilizing enzyme family
G9272_RS04635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G9272_RS04645	COG0517	IMP dehydrogenase activity
G9272_RS04645	COG0516	GMP reductase activity
G9272_RS04665	COG1063	alcohol dehydrogenase
G9272_RS04680	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G9272_RS04710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G9272_RS04720	COG0549	Belongs to the carbamate kinase family
G9272_RS04735	COG0531	amino acid
G9272_RS04745	COG0516	GMP reductase activity
G9272_RS04745	COG0517	IMP dehydrogenase activity
G9272_RS04755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G9272_RS04770	COG1454	alcohol dehydrogenase
G9272_RS04770	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS04780	COG4716	Myosin-crossreactive antigen
G9272_RS04835	COG0702	epimerase
G9272_RS04865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9272_RS04885	COG1960	acyl-CoA dehydrogenase activity
G9272_RS04900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G9272_RS04905	COG4191	Histidine kinase
G9272_RS04915	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G9272_RS04920	COG0698	ribose 5-phosphate isomerase
G9272_RS04945	COG2376	Dihydroxyacetone kinase
G9272_RS04950	COG1461	Dihydroxyacetone kinase
G9272_RS04955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G9272_RS04955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9272_RS04955	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
G9272_RS04980	COG1902	pentaerythritol trinitrate reductase activity
G9272_RS04980	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9272_RS05005	COG2890	protein-(glutamine-N5) methyltransferase activity
G9272_RS05025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G9272_RS05040	COG3458	cephalosporin-C deacetylase activity
G9272_RS05050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G9272_RS05055	COG2188	Transcriptional regulator
G9272_RS05085	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS05090	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G9272_RS05095	COG1686	Belongs to the peptidase S11 family
G9272_RS05110	COG2066	Belongs to the glutaminase family
G9272_RS05125	COG1113	amino acid transport
G9272_RS05130	COG2186	Transcriptional regulator
G9272_RS05135	COG1968	undecaprenyl-diphosphatase activity
G9272_RS05140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G9272_RS05145	COG1993	acr, cog1993
G9272_RS05150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G9272_RS05160	COG0640	Transcriptional regulator
G9272_RS05180	COG1175	transmembrane transport
G9272_RS05185	COG0395	ABC-type sugar transport system, permease component
G9272_RS05230	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G9272_RS05245	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS05250	COG1802	Transcriptional regulator
G9272_RS05270	COG0402	S-adenosylhomocysteine deaminase activity
G9272_RS05280	COG0179	Fumarylacetoacetate (FAA) hydrolase
G9272_RS05285	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS05290	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS05300	COG0346	lactoylglutathione lyase activity
G9272_RS05305	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G9272_RS05310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G9272_RS05315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G9272_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS05350	COG2353	YceI-like domain
G9272_RS05355	COG0395	ABC-type sugar transport system, permease component
G9272_RS05395	COG4221	oxidoreductase activity
G9272_RS05410	COG2072	flavoprotein involved in K transport
G9272_RS05420	COG1309	transcriptional regulator
G9272_RS05455	COG0784	Response regulator, receiver
G9272_RS05460	COG4251	negative regulation of phosphorylation
G9272_RS05495	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS05550	COG2045	Belongs to the ComB family
G9272_RS05555	COG1191	sigma factor activity
G9272_RS05575	COG1621	beta-fructofuranosidase activity
G9272_RS05600	COG1609	Transcriptional regulator
G9272_RS05670	COG1309	transcriptional regulator
G9272_RS05695	COG0667	Aldo Keto reductase
G9272_RS05700	COG0667	Aldo Keto reductase
G9272_RS05725	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS05765	COG2197	response regulator
G9272_RS05780	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS05785	COG0745	RESPONSE REGULATOR receiver
G9272_RS05790	COG0642	Histidine kinase
G9272_RS05810	COG0402	S-adenosylhomocysteine deaminase activity
G9272_RS05840	COG0640	Transcriptional regulator
G9272_RS05860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G9272_RS05865	COG0492	ferredoxin-NADP+ reductase activity
G9272_RS05875	COG2315	Protein conserved in bacteria
G9272_RS05880	COG2315	Protein conserved in bacteria
G9272_RS05935	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G9272_RS05935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9272_RS05940	COG2186	Transcriptional regulator
G9272_RS05945	COG0778	Nitroreductase
G9272_RS05950	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G9272_RS05975	COG0604	alcohol dehydrogenase
G9272_RS05975	COG3321	synthase
G9272_RS06005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9272_RS06015	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G9272_RS06040	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS06045	COG1960	acyl-CoA dehydrogenase activity
G9272_RS06055	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9272_RS06055	COG1902	pentaerythritol trinitrate reductase activity
G9272_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS06110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G9272_RS06115	COG1215	transferase activity, transferring glycosyl groups
G9272_RS06140	COG0464	growth
G9272_RS06150	COG1349	DNA-binding transcription factor activity
G9272_RS06175	COG0577	efflux transmembrane transporter activity
G9272_RS06180	COG1136	(ABC) transporter
G9272_RS06220	COG1309	transcriptional regulator
G9272_RS06225	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS06230	COG1940	carbohydrate kinase activity
G9272_RS06240	COG2813	Specifically methylates the guanine in position
G9272_RS06250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G9272_RS06255	COG1349	DNA-binding transcription factor activity
G9272_RS06265	COG0326	Molecular chaperone. Has ATPase activity
G9272_RS06290	COG2197	response regulator
G9272_RS06300	COG0738	Major facilitator superfamily
G9272_RS06325	COG2197	response regulator
G9272_RS06330	COG4585	Histidine kinase
G9272_RS06345	COG0445	tRNA wobble uridine modification
G9272_RS06360	COG1660	Displays ATPase and GTPase activities
G9272_RS06405	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G9272_RS06430	COG0204	Acyl-transferase
G9272_RS06465	COG0584	glycerophosphoryl diester phosphodiesterase
G9272_RS06490	COG1846	Transcriptional regulator
G9272_RS06510	COG0671	phosphoesterase, PA-phosphatase related
G9272_RS06525	COG1309	transcriptional regulator
G9272_RS06550	COG2233	PERMEase
G9272_RS06570	COG3509	depolymerase
G9272_RS06585	COG1960	acyl-CoA dehydrogenase activity
G9272_RS06600	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G9272_RS06605	COG2971	BadF BadG BcrA BcrD
G9272_RS06615	COG2706	6-phosphogluconolactonase activity
G9272_RS06655	COG1278	Cold shock
G9272_RS06670	COG0714	Associated with various cellular activities
G9272_RS06685	COG2318	DinB family
G9272_RS06705	COG1174	glycine betaine transport
G9272_RS06740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G9272_RS06745	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS06750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9272_RS06750	COG3321	synthase
G9272_RS06780	COG0513	Belongs to the DEAD box helicase family
G9272_RS06785	COG1278	Cold shock
G9272_RS06815	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9272_RS06820	COG1129	ABC transporter
G9272_RS06860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9272_RS06860	COG0723	plastoquinol--plastocyanin reductase activity
G9272_RS06870	COG0667	Aldo Keto reductase
G9272_RS06885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G9272_RS06890	COG0395	ABC-type sugar transport system, permease component
G9272_RS06900	COG3842	ATPase activity
G9272_RS06910	COG3608	succinylglutamate desuccinylase aspartoacylase
G9272_RS06935	COG0247	lactate metabolic process
G9272_RS06935	COG0277	FAD linked oxidase domain protein
G9272_RS06940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G9272_RS06955	COG2072	flavoprotein involved in K transport
G9272_RS06965	COG1132	(ABC) transporter
G9272_RS06975	COG1301	dicarboxylic acid transport
G9272_RS06990	COG1132	(ABC) transporter
G9272_RS06995	COG1132	(ABC) transporter
G9272_RS07005	COG0254	rRNA binding
G9272_RS07020	COG1946	Acyl-CoA thioesterase
G9272_RS07030	COG2018	Roadblock/LC7 domain
G9272_RS07125	COG1070	Carbohydrate kinase
G9272_RS07130	COG1846	Transcriptional regulator
G9272_RS07130	COG1940	carbohydrate kinase activity
G9272_RS07145	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS07240	COG3693	PFAM glycoside hydrolase, family 10
G9272_RS07245	COG1408	metallophosphoesterase
G9272_RS07260	COG2706	6-phosphogluconolactonase activity
G9272_RS07280	COG1609	Transcriptional regulator
G9272_RS07290	COG1175	transmembrane transport
G9272_RS07295	COG0395	ABC-type sugar transport system, permease component
G9272_RS07300	COG5297	Belongs to the glycosyl hydrolase family 6
G9272_RS07340	COG0583	DNA-binding transcription factor activity
G9272_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS07395	COG2130	NADP-dependent
G9272_RS07400	COG0789	Transcriptional regulator
G9272_RS07410	COG1609	Transcriptional regulator
G9272_RS07415	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G9272_RS07425	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G9272_RS07430	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G9272_RS07440	COG0179	Fumarylacetoacetate (FAA) hydrolase
G9272_RS07455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9272_RS07490	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G9272_RS07495	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G9272_RS07500	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
G9272_RS07535	COG1231	oxidoreductase activity
G9272_RS07540	COG1090	epimerase
G9272_RS07575	COG3903	Transcriptional regulator
G9272_RS07575	COG3629	intracellular signal transduction
G9272_RS07580	COG0596	Alpha beta hydrolase
G9272_RS07600	COG2027	D-alanyl-D-alanine carboxypeptidase
G9272_RS07630	COG1082	Xylose isomerase domain protein TIM barrel
G9272_RS07635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9272_RS07645	COG3718	enzyme involved in inositol metabolism
G9272_RS07650	COG3962	Belongs to the TPP enzyme family
G9272_RS07665	COG1082	Xylose isomerase domain protein TIM barrel
G9272_RS07680	COG4213	ABC transporter substrate-binding protein
G9272_RS07690	COG4213	ABC transporter substrate-binding protein
G9272_RS07695	COG4214	carbohydrate transport
G9272_RS07705	COG4552	Acetyltransferase involved in intracellular survival and related
G9272_RS07735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9272_RS07740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9272_RS07800	COG1082	Xylose isomerase domain protein TIM barrel
G9272_RS07835	COG0475	glutathione-regulated potassium exporter activity
G9272_RS07845	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9272_RS07880	COG1960	acyl-CoA dehydrogenase activity
G9272_RS07885	COG1960	acyl-CoA dehydrogenase activity
G9272_RS07900	COG3634	alkyl hydroperoxide reductase activity
G9272_RS07905	COG1793	dna ligase
G9272_RS07930	COG1960	acyl-CoA dehydrogenase activity
G9272_RS07940	COG0242	peptide deformylase activity
G9272_RS07950	COG3442	glutamine amidotransferase
G9272_RS07955	COG0205	6-phosphofructokinase activity
G9272_RS07970	COG3275	phosphorelay sensor kinase activity
G9272_RS07975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9272_RS07985	COG3279	Response regulator of the LytR AlgR family
G9272_RS07990	COG1522	sequence-specific DNA binding
G9272_RS07995	COG1834	amidinotransferase
G9272_RS08000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G9272_RS08025	COG0829	nickel cation binding
G9272_RS08030	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G9272_RS08035	COG0830	nickel cation binding
G9272_RS08040	COG0804	urea catabolic process
G9272_RS08045	COG0832	Belongs to the urease beta subunit family
G9272_RS08050	COG0831	urea catabolic process
G9272_RS08055	COG1309	transcriptional regulator
G9272_RS08070	COG0740	serine-type endopeptidase activity
G9272_RS08105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G9272_RS08110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G9272_RS08115	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G9272_RS08125	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G9272_RS08130	COG2226	methyltransferase
G9272_RS08145	COG0577	efflux transmembrane transporter activity
G9272_RS08145	COG1136	(ABC) transporter
G9272_RS08150	COG0577	efflux transmembrane transporter activity
G9272_RS08150	COG1136	(ABC) transporter
G9272_RS08180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G9272_RS08185	COG3663	DNA glycosylase
G9272_RS08205	COG4585	Histidine kinase
G9272_RS08210	COG2197	response regulator
G9272_RS08215	COG1940	carbohydrate kinase activity
G9272_RS08220	COG2188	Transcriptional regulator
G9272_RS08235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9272_RS08250	COG0626	cystathionine gamma-synthase activity
G9272_RS08270	COG1522	sequence-specific DNA binding
G9272_RS08275	COG0419	ATPase involved in DNA repair
G9272_RS08280	COG0420	3'-5' exonuclease activity
G9272_RS08285	COG1739	Uncharacterized protein family UPF0029
G9272_RS08305	COG1832	CoA-binding protein
G9272_RS08315	COG0640	Transcriptional regulator
G9272_RS08340	COG0110	maltose O-acetyltransferase activity
G9272_RS08365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G9272_RS08385	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G9272_RS08400	COG0183	Belongs to the thiolase family
G9272_RS08430	COG1968	undecaprenyl-diphosphatase activity
G9272_RS08515	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G9272_RS08535	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G9272_RS08540	COG0747	negative chemotaxis
G9272_RS08580	COG0583	DNA-binding transcription factor activity
G9272_RS08585	COG0697	spore germination
G9272_RS08620	COG1695	Transcriptional regulator
G9272_RS08625	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS08690	COG1609	Transcriptional regulator
G9272_RS08705	COG1175	transmembrane transport
G9272_RS08725	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G9272_RS08725	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G9272_RS08740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G9272_RS08760	COG1716	ATPase activity
G9272_RS08780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G9272_RS08810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G9272_RS08820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G9272_RS08830	COG2816	NAD+ diphosphatase activity
G9272_RS08835	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
G9272_RS08845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G9272_RS08850	COG3706	GGDEF domain
G9272_RS08855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G9272_RS08860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G9272_RS08915	COG2814	Major facilitator Superfamily
G9272_RS08920	COG4336	lyase activity
G9272_RS08925	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G9272_RS08930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G9272_RS08935	COG1984	allophanate hydrolase subunit 2
G9272_RS08950	COG0438	transferase activity, transferring glycosyl groups
G9272_RS08955	COG0438	transferase activity, transferring glycosyl groups
G9272_RS08985	COG2364	Membrane
G9272_RS08995	COG2270	Major facilitator Superfamily
G9272_RS09010	COG1216	Glycosyl transferase, family 2
G9272_RS09030	COG1960	acyl-CoA dehydrogenase activity
G9272_RS09055	COG0237	dephospho-CoA kinase activity
G9272_RS09080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G9272_RS09085	COG0140	phosphoribosyl-ATP diphosphatase activity
G9272_RS09090	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G9272_RS09095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G9272_RS09095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G9272_RS09100	COG3201	nicotinamide mononucleotide transporter
G9272_RS09110	COG1090	epimerase
G9272_RS09115	COG1846	Transcriptional regulator
G9272_RS09115	COG1940	carbohydrate kinase activity
G9272_RS09120	COG2223	nitrite transmembrane transporter activity
G9272_RS09130	COG2233	PERMEase
G9272_RS09150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G9272_RS09160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9272_RS09165	COG3842	ATPase activity
G9272_RS09175	COG1176	ABC-type spermidine putrescine transport system, permease component I
G9272_RS09185	COG2188	Transcriptional regulator
G9272_RS09195	COG0531	amino acid
G9272_RS09215	COG2390	Transcriptional regulator
G9272_RS09220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G9272_RS09225	COG2409	Drug exporters of the RND superfamily
G9272_RS09230	COG0137	argininosuccinate synthase activity
G9272_RS09240	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G9272_RS09255	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G9272_RS09265	COG1758	RNA polymerase activity
G9272_RS09270	COG0194	GDP metabolic process
G9272_RS09280	COG0284	orotidine-5'-phosphate decarboxylase activity
G9272_RS09285	COG0167	dihydroorotate dehydrogenase activity
G9272_RS09290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G9272_RS09295	COG0505	Belongs to the CarA family
G9272_RS09305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G9272_RS09310	COG0540	Belongs to the ATCase OTCase family
G9272_RS09315	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G9272_RS09325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G9272_RS09330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G9272_RS09335	COG0006	proline dipeptidase activity
G9272_RS09345	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G9272_RS09350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G9272_RS09355	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G9272_RS09360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G9272_RS09370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G9272_RS09375	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G9272_RS09390	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G9272_RS09405	COG0124	histidyl-tRNA synthetase
G9272_RS09415	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G9272_RS09420	COG1196	nuclear chromosome segregation
G9272_RS09425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G9272_RS09430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G9272_RS09435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G9272_RS09440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G9272_RS09450	COG2255	four-way junction helicase activity
G9272_RS09455	COG0632	four-way junction helicase activity
G9272_RS09460	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G9272_RS09465	COG0217	transcriptional regulatory protein
G9272_RS09470	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
G9272_RS09475	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
G9272_RS09485	COG0438	transferase activity, transferring glycosyl groups
G9272_RS09490	COG1560	Kdo2-lipid A biosynthetic process
G9272_RS09495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G9272_RS09515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G9272_RS09520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G9272_RS09535	COG5002	protein histidine kinase activity
G9272_RS09535	COG2176	DNA-directed DNA polymerase activity
G9272_RS09565	COG0395	ABC-type sugar transport system, permease component
G9272_RS09570	COG1175	transmembrane transport
G9272_RS09575	COG1653	transport
G9272_RS09625	COG0512	Glutamine amidotransferase of anthranilate synthase
G9272_RS09625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G9272_RS09680	COG1595	DNA-templated transcription, initiation
G9272_RS09700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G9272_RS09700	COG1648	precorrin-2 dehydrogenase activity
G9272_RS09705	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G9272_RS09720	COG1464	Belongs to the NlpA lipoprotein family
G9272_RS09725	COG2011	ABC-type metal ion transport system permease component
G9272_RS09730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G9272_RS09760	COG0204	Acyl-transferase
G9272_RS09760	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS09765	COG0477	Major facilitator Superfamily
G9272_RS09780	COG0165	Argininosuccinate lyase
G9272_RS09805	COG1017	nitric oxide dioxygenase activity
G9272_RS09805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9272_RS09820	COG1438	arginine binding
G9272_RS09825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G9272_RS09830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G9272_RS09835	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G9272_RS09840	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G9272_RS09875	COG0697	spore germination
G9272_RS09885	COG1649	PFAM Uncharacterised BCR, COG1649
G9272_RS09915	COG0072	phenylalanine-tRNA ligase activity
G9272_RS09915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9272_RS09920	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G9272_RS09925	COG5002	protein histidine kinase activity
G9272_RS09930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G9272_RS09935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G9272_RS09940	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G9272_RS09945	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G9272_RS09980	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS09985	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS09990	COG0174	glutamine synthetase
G9272_RS10000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G9272_RS10015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G9272_RS10025	COG4176	ABC-type proline glycine betaine transport system permease component
G9272_RS10030	COG0517	IMP dehydrogenase activity
G9272_RS10030	COG4175	Glycine betaine
G9272_RS10035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G9272_RS10110	COG1309	transcriptional regulator
G9272_RS10145	COG0805	protein transport
G9272_RS10150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G9272_RS10180	COG0545	Peptidyl-prolyl cis-trans isomerase
G9272_RS10185	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G9272_RS10195	COG1609	Transcriptional regulator
G9272_RS10200	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G9272_RS10205	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G9272_RS10220	COG4122	O-methyltransferase activity
G9272_RS10225	COG1222	aaa ATPase
G9272_RS10245	COG0517	IMP dehydrogenase activity
G9272_RS10245	COG1994	Peptidase M50
G9272_RS10255	COG2197	response regulator
G9272_RS10260	COG0747	negative chemotaxis
G9272_RS10265	COG4166	transmembrane transport
G9272_RS10270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9272_RS10275	COG0646	methionine synthase
G9272_RS10275	COG1410	methionine synthase
G9272_RS10280	COG1414	Transcriptional regulator
G9272_RS10285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G9272_RS10290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G9272_RS10295	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G9272_RS10300	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
G9272_RS10310	COG1129	ABC transporter
G9272_RS10320	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
G9272_RS10325	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
G9272_RS10335	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
G9272_RS10335	COG0235	Class ii aldolase
G9272_RS10345	COG3845	ABC transporter
G9272_RS10355	COG1079	Belongs to the binding-protein-dependent transport system permease family
G9272_RS10360	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
G9272_RS10365	COG0402	S-adenosylhomocysteine deaminase activity
G9272_RS10370	COG2186	Transcriptional regulator
G9272_RS10380	COG0215	cysteine-tRNA ligase activity
G9272_RS10395	COG0406	alpha-ribazole phosphatase activity
G9272_RS10400	COG0598	Magnesium transport protein CorA
G9272_RS10410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS10415	COG0667	Aldo Keto reductase
G9272_RS10445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G9272_RS10470	COG0308	aminopeptidase N
G9272_RS10475	COG3012	SEC-C Motif Domain Protein
G9272_RS10480	COG2186	Transcriptional regulator
G9272_RS10485	COG3265	gluconokinase activity
G9272_RS10495	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS10500	COG1063	alcohol dehydrogenase
G9272_RS10525	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
G9272_RS10530	COG2149	membrane
G9272_RS10565	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS10620	COG1960	acyl-CoA dehydrogenase activity
G9272_RS10630	COG0640	Transcriptional regulator
G9272_RS10670	COG2851	Citrate transporter
G9272_RS10680	COG1309	transcriptional regulator
G9272_RS10690	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G9272_RS10695	COG2188	Transcriptional regulator
G9272_RS10720	COG1595	DNA-templated transcription, initiation
G9272_RS10740	COG2815	serine threonine protein kinase
G9272_RS10740	COG0515	serine threonine protein kinase
G9272_RS10745	COG2755	lipolytic protein G-D-S-L family
G9272_RS10780	COG1725	Transcriptional regulator
G9272_RS10795	COG2226	methyltransferase
G9272_RS10820	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G9272_RS10820	COG0662	Cupin 2, conserved barrel domain protein
G9272_RS10830	COG0587	DNA-directed DNA polymerase activity
G9272_RS10840	COG0330	HflC and HflK could
G9272_RS10880	COG1799	cell septum assembly
G9272_RS10885	COG1960	acyl-CoA dehydrogenase activity
G9272_RS10890	COG0477	Major facilitator Superfamily
G9272_RS10900	COG0671	phosphoesterase, PA-phosphatase related
G9272_RS10910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G9272_RS10920	COG1652	LysM domain
G9272_RS10935	COG1160	GTP binding
G9272_RS10945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G9272_RS10985	COG1187	pseudouridine synthase activity
G9272_RS10990	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G9272_RS10995	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G9272_RS11010	COG0686	Belongs to the AlaDH PNT family
G9272_RS11020	COG0494	nUDIX hydrolase
G9272_RS11025	COG0504	CTP synthase activity
G9272_RS11030	COG3387	PFAM Glycoside hydrolase 15-related
G9272_RS11050	COG0438	transferase activity, transferring glycosyl groups
G9272_RS11060	COG0497	DNA recombination
G9272_RS11065	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G9272_RS11085	COG1120	ATPase activity
G9272_RS11090	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9272_RS11095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9272_RS11100	COG0647	UMP catabolic process
G9272_RS11135	COG2094	Belongs to the DNA glycosylase MPG family
G9272_RS11145	COG1881	PFAM PEBP family protein
G9272_RS11165	COG1119	ATPase activity
G9272_RS11185	COG2197	response regulator
G9272_RS11190	COG4585	Histidine kinase
G9272_RS11195	COG4221	oxidoreductase activity
G9272_RS11200	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G9272_RS11210	COG1716	ATPase activity
G9272_RS11210	COG1131	(ABC) transporter
G9272_RS11210	COG0842	Transport permease protein
G9272_RS11220	COG0560	Phosphoserine phosphatase
G9272_RS11220	COG3830	Belongs to the UPF0237 family
G9272_RS11225	COG0588	phosphoglycerate mutase activity
G9272_RS11240	COG2186	Transcriptional regulator
G9272_RS11255	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS11270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G9272_RS11290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G9272_RS11295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9272_RS11310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G9272_RS11340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G9272_RS11360	COG1966	Carbon starvation protein
G9272_RS11380	COG3387	PFAM Glycoside hydrolase 15-related
G9272_RS11430	COG0488	(ABC) transporter
G9272_RS11450	COG0235	Class ii aldolase
G9272_RS11470	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G9272_RS11475	COG1492	cobalamin metabolic process
G9272_RS11495	COG1797	cobyrinic acid a,c-diamide synthase activity
G9272_RS11555	COG0765	amino acid transport
G9272_RS11565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G9272_RS11570	COG2318	DinB family
G9272_RS11575	COG0456	acetyltransferase
G9272_RS11580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G9272_RS11585	COG1917	Cupin 2, conserved barrel domain protein
G9272_RS11590	COG5285	phytanoyl-CoA dioxygenase
G9272_RS11595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G9272_RS11620	COG1414	Transcriptional regulator
G9272_RS11630	COG0768	penicillin binding
G9272_RS11635	COG2252	PERMEase
G9272_RS11640	COG1595	DNA-templated transcription, initiation
G9272_RS11650	COG4733	cellulase activity
G9272_RS11675	COG4677	pectinesterase activity
G9272_RS11680	COG3866	Pectate lyase
G9272_RS11685	COG2755	lipolytic protein G-D-S-L family
G9272_RS11700	COG3507	Belongs to the glycosyl hydrolase 43 family
G9272_RS11715	COG3866	Pectate lyase
G9272_RS11720	COG0395	ABC-type sugar transport system, permease component
G9272_RS11725	COG1175	transmembrane transport
G9272_RS11735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G9272_RS11740	COG1802	Transcriptional regulator
G9272_RS11745	COG1234	tRNA 3'-trailer cleavage
G9272_RS11765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G9272_RS11770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G9272_RS11775	COG1349	DNA-binding transcription factor activity
G9272_RS11785	COG1309	transcriptional regulator
G9272_RS11800	COG1802	Transcriptional regulator
G9272_RS11805	COG1309	transcriptional regulator
G9272_RS11815	COG0583	DNA-binding transcription factor activity
G9272_RS11820	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS11860	COG3835	regulator
G9272_RS11865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9272_RS11870	COG0765	amino acid transport
G9272_RS11875	COG1126	abc transporter atp-binding protein
G9272_RS11880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9272_RS11895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G9272_RS11905	COG1595	DNA-templated transcription, initiation
G9272_RS11945	COG3903	Transcriptional regulator
G9272_RS11945	COG3629	intracellular signal transduction
G9272_RS11955	COG2171	N-acyltransferase activity
G9272_RS11965	COG3226	Transcriptional regulator
G9272_RS11970	COG2076	Multidrug Resistance protein
G9272_RS11980	COG2151	metal-sulfur cluster biosynthetic enzyme
G9272_RS11985	COG0822	iron-sulfur transferase activity
G9272_RS11990	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G9272_RS11995	COG0396	ATPase activity
G9272_RS12005	COG0719	Fe-S assembly protein
G9272_RS12020	COG2746	aminoglycoside 3-N-acetyltransferase activity
G9272_RS12025	COG1131	(ABC) transporter
G9272_RS12035	COG1612	heme a metabolic process
G9272_RS12055	COG0109	protoheme IX farnesyltransferase activity
G9272_RS12065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G9272_RS12080	COG0363	glucosamine-6-phosphate deaminase activity
G9272_RS12090	COG0166	Belongs to the GPI family
G9272_RS12100	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G9272_RS12105	COG0149	triose-phosphate isomerase activity
G9272_RS12110	COG0126	phosphoglycerate kinase activity
G9272_RS12115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G9272_RS12125	COG1481	regulation of sporulation
G9272_RS12130	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G9272_RS12135	COG1660	Displays ATPase and GTPase activities
G9272_RS12140	COG0322	excinuclease ABC activity
G9272_RS12165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G9272_RS12175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G9272_RS12180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9272_RS12185	COG0765	amino acid transport
G9272_RS12195	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G9272_RS12200	COG1619	proteins homologs of microcin C7 resistance protein MccF
G9272_RS12205	COG0477	Major facilitator Superfamily
G9272_RS12210	COG0387	Pfam Sodium calcium exchanger
G9272_RS12230	COG0556	nucleotide-excision repair
G9272_RS12240	COG0584	glycerophosphoryl diester phosphodiesterase
G9272_RS12245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G9272_RS12250	COG0477	Major facilitator Superfamily
G9272_RS12260	COG2313	pseudouridylate synthase activity
G9272_RS12265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9272_RS12270	COG2226	methyltransferase
G9272_RS12275	COG0598	Magnesium transport protein CorA
G9272_RS12305	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9272_RS12310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9272_RS12395	COG1953	Uracil, thiamine, allantoin
G9272_RS12400	COG1802	Transcriptional regulator
G9272_RS12425	COG2226	methyltransferase
G9272_RS12440	COG0237	dephospho-CoA kinase activity
G9272_RS12450	COG0539	negative regulation of cytoplasmic translation
G9272_RS12455	COG2226	methyltransferase
G9272_RS12460	COG1643	Atp-dependent helicase
G9272_RS12500	COG2050	protein possibly involved in aromatic compounds catabolism
G9272_RS12530	COG0411	ABC transporter
G9272_RS12565	COG0737	Belongs to the 5'-nucleotidase family
G9272_RS12585	COG0287	Prephenate dehydrogenase
G9272_RS12585	COG1605	Chorismate mutase
G9272_RS12595	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS12605	COG1024	Enoyl-CoA hydratase
G9272_RS12625	COG0183	Belongs to the thiolase family
G9272_RS12630	COG1309	transcriptional regulator
G9272_RS12635	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS12640	COG1960	acyl-CoA dehydrogenase activity
G9272_RS12660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G9272_RS12670	COG2304	oxidoreductase activity
G9272_RS12685	COG0070	glutamate synthase
G9272_RS12685	COG0067	glutamate synthase
G9272_RS12685	COG0069	glutamate synthase activity
G9272_RS12715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9272_RS12720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G9272_RS12730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G9272_RS12740	COG0159	tryptophan synthase activity
G9272_RS12745	COG0133	tryptophan synthase activity
G9272_RS12755	COG0134	indole-3-glycerol-phosphate synthase activity
G9272_RS12780	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G9272_RS12805	COG0107	imidazoleglycerol-phosphate synthase activity
G9272_RS12810	COG0251	oxidation-reduction process
G9272_RS12815	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G9272_RS12820	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G9272_RS12830	COG0131	Imidazoleglycerol-phosphate dehydratase
G9272_RS12835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G9272_RS12840	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G9272_RS12880	COG1432	Conserved Protein
G9272_RS12890	COG0587	DNA-directed DNA polymerase activity
G9272_RS12925	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS12935	COG2153	protein acetylation
G9272_RS12945	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G9272_RS12955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G9272_RS12960	COG3599	regulation of cell shape
G9272_RS12970	COG1799	cell septum assembly
G9272_RS12980	COG1496	oxidoreductase activity
G9272_RS12985	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G9272_RS12990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G9272_RS12995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G9272_RS13005	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G9272_RS13010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G9272_RS13020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G9272_RS13035	COG0275	rRNA processing
G9272_RS13045	COG0714	Associated with various cellular activities
G9272_RS13075	COG1126	abc transporter atp-binding protein
G9272_RS13085	COG1309	transcriptional regulator
G9272_RS13110	COG0352	thiamine-phosphate diphosphorylase activity
G9272_RS13130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9272_RS13130	COG2022	thiamine diphosphate biosynthetic process
G9272_RS13140	COG2022	thiamine diphosphate biosynthetic process
G9272_RS13145	COG0515	serine threonine protein kinase
G9272_RS13145	COG2815	serine threonine protein kinase
G9272_RS13150	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G9272_RS13155	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G9272_RS13160	COG2193	ferroxidase activity
G9272_RS13165	COG0243	molybdopterin cofactor binding
G9272_RS13170	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G9272_RS13185	COG0205	6-phosphofructokinase activity
G9272_RS13220	COG1940	carbohydrate kinase activity
G9272_RS13230	COG0003	Pfam Anion-transporting ATPase
G9272_RS13260	COG0534	Mate efflux family protein
G9272_RS13280	COG3103	Sh3 type 3 domain protein
G9272_RS13280	COG1388	LysM domain
G9272_RS13280	COG0791	NLP P60 protein
G9272_RS13305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G9272_RS13310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G9272_RS13315	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G9272_RS13320	COG0723	plastoquinol--plastocyanin reductase activity
G9272_RS13325	COG2010	Cytochrome c
G9272_RS13330	COG1845	cytochrome c oxidase, subunit III
G9272_RS13340	COG1376	ErfK ybiS ycfS ynhG family protein
G9272_RS13350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G9272_RS13355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G9272_RS13365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9272_RS13385	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G9272_RS13390	COG0515	serine threonine protein kinase
G9272_RS13390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9272_RS13395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G9272_RS13400	COG2197	response regulator
G9272_RS13405	COG4585	Histidine kinase
G9272_RS13445	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G9272_RS13450	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G9272_RS13450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G9272_RS13465	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G9272_RS13475	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G9272_RS13480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G9272_RS13485	COG0508	dehydrogenase complex catalyzes the overall conversion of
G9272_RS13495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G9272_RS13545	COG0321	lipoyl(octanoyl) transferase activity
G9272_RS13550	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G9272_RS13570	COG0174	glutamine synthetase
G9272_RS13605	COG2226	methyltransferase
G9272_RS13630	COG0501	Belongs to the peptidase M48B family
G9272_RS13690	COG0745	RESPONSE REGULATOR receiver
G9272_RS13705	COG2197	response regulator
G9272_RS13740	COG1309	transcriptional regulator
G9272_RS13770	COG0366	Alpha amylase catalytic
G9272_RS13775	COG3833	ABC-type maltose transport systems, permease component
G9272_RS13780	COG1175	transmembrane transport
G9272_RS13785	COG2182	Extracellular solute-binding protein
G9272_RS13790	COG1609	Transcriptional regulator
G9272_RS13800	COG0583	DNA-binding transcription factor activity
G9272_RS13805	COG0697	spore germination
G9272_RS13810	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G9272_RS13825	COG0174	glutamine synthetase
G9272_RS13830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9272_RS13830	COG1017	nitric oxide dioxygenase activity
G9272_RS13840	COG3835	regulator
G9272_RS13855	COG1959	2 iron, 2 sulfur cluster binding
G9272_RS13875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G9272_RS13875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G9272_RS13880	COG3896	Chloramphenicol phosphotransferase-like protein
G9272_RS13895	COG2814	Major facilitator Superfamily
G9272_RS13910	COG0477	Major facilitator Superfamily
G9272_RS13915	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G9272_RS13935	COG1994	Peptidase M50
G9272_RS13985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9272_RS13990	COG1120	ATPase activity
G9272_RS14000	COG2837	iron assimilation
G9272_RS14005	COG0672	)-iron permease
G9272_RS14020	COG1309	transcriptional regulator
G9272_RS14030	COG2814	Major facilitator Superfamily
G9272_RS14035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G9272_RS14045	COG3540	Alkaline phosphatase
G9272_RS14055	COG1686	Belongs to the peptidase S11 family
G9272_RS14065	COG1136	(ABC) transporter
G9272_RS14075	COG2259	Doxx family
G9272_RS14110	COG1113	amino acid transport
G9272_RS14130	COG3022	response to hydroperoxide
G9272_RS14135	COG0800	Aldolase
G9272_RS14150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G9272_RS14175	COG2030	dehydratase
G9272_RS14185	COG2197	response regulator
G9272_RS14200	COG0477	Major facilitator Superfamily
G9272_RS14220	COG0860	N-Acetylmuramoyl-L-alanine amidase
G9272_RS14230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS14250	COG0438	transferase activity, transferring glycosyl groups
G9272_RS14255	COG1309	transcriptional regulator
G9272_RS14315	COG3845	ABC transporter
G9272_RS14330	COG3619	membrane
G9272_RS14345	COG2124	cytochrome p450
G9272_RS14350	COG0183	Belongs to the thiolase family
G9272_RS14425	COG4122	O-methyltransferase activity
G9272_RS14505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G9272_RS14525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G9272_RS14590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G9272_RS14605	COG1358	cellular component organization or biogenesis
G9272_RS14650	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G9272_RS14655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G9272_RS14665	COG0477	Major facilitator Superfamily
G9272_RS14670	COG1309	transcriptional regulator
G9272_RS14685	COG0667	Aldo Keto reductase
G9272_RS14690	COG0789	Transcriptional regulator
G9272_RS14705	COG1741	Belongs to the pirin family
G9272_RS14720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G9272_RS14725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9272_RS14730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9272_RS14760	COG1280	lysine exporter protein (LysE YggA)
G9272_RS14775	COG2130	NADP-dependent
G9272_RS14805	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9272_RS14810	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9272_RS14820	COG1879	ABC-type sugar transport system periplasmic component
G9272_RS14825	COG1609	Transcriptional regulator
G9272_RS14855	COG1129	ABC transporter
G9272_RS14860	COG4214	carbohydrate transport
G9272_RS14865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G9272_RS14870	COG3507	Belongs to the glycosyl hydrolase 43 family
G9272_RS14925	COG0395	ABC-type sugar transport system, permease component
G9272_RS14930	COG1175	transmembrane transport
G9272_RS14955	COG3386	PFAM SMP-30 Gluconolaconase
G9272_RS14960	COG1414	Transcriptional regulator
G9272_RS14980	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS14985	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G9272_RS14985	COG0825	malonyl-CoA metabolic process
G9272_RS15000	COG0464	growth
G9272_RS15015	COG1077	Cell shape determining protein MreB Mrl
G9272_RS15020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9272_RS15050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G9272_RS15085	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G9272_RS15090	COG0604	alcohol dehydrogenase
G9272_RS15090	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS15090	COG3321	synthase
G9272_RS15115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G9272_RS15135	COG2205	protein histidine kinase activity
G9272_RS15150	COG3345	alpha-galactosidase
G9272_RS15155	COG1609	Transcriptional regulator
G9272_RS15190	COG1597	lipid kinase activity
G9272_RS15210	COG3345	alpha-galactosidase
G9272_RS15215	COG1396	sequence-specific DNA binding
G9272_RS15220	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
G9272_RS15285	COG1070	Carbohydrate kinase
G9272_RS15300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G9272_RS15305	COG0358	DNA primase activity
G9272_RS15315	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G9272_RS15325	COG2949	membrane
G9272_RS15330	COG0243	molybdopterin cofactor binding
G9272_RS15340	COG0477	Major facilitator Superfamily
G9272_RS15390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G9272_RS15395	COG2146	nitrite reductase [NAD(P)H] activity
G9272_RS15395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G9272_RS15405	COG0642	Histidine kinase
G9272_RS15410	COG0745	RESPONSE REGULATOR receiver
G9272_RS15425	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS15445	COG0596	Alpha beta hydrolase
G9272_RS15455	COG1136	(ABC) transporter
G9272_RS15465	COG1132	(ABC) transporter
G9272_RS15470	COG0574	Belongs to the PEP-utilizing enzyme family
G9272_RS15470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G9272_RS15475	COG1940	carbohydrate kinase activity
G9272_RS15475	COG1846	Transcriptional regulator
G9272_RS15480	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
G9272_RS15510	COG0477	Major facilitator Superfamily
G9272_RS15520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G9272_RS15530	COG0667	Aldo Keto reductase
G9272_RS15555	COG2755	lipolytic protein G-D-S-L family
G9272_RS15560	COG0423	glycine-tRNA ligase activity
G9272_RS15570	COG1121	(ABC) transporter
G9272_RS15575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G9272_RS15590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G9272_RS15595	COG1381	Involved in DNA repair and RecF pathway recombination
G9272_RS15635	COG0456	acetyltransferase
G9272_RS15635	COG1214	PFAM Peptidase M22, glycoprotease
G9272_RS15645	COG1595	DNA-templated transcription, initiation
G9272_RS15655	COG2197	response regulator
G9272_RS15660	COG4585	Histidine kinase
G9272_RS15665	COG2409	Drug exporters of the RND superfamily
G9272_RS15675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G9272_RS15690	COG2723	6-phospho-beta-galactosidase activity
G9272_RS15710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G9272_RS15745	COG2315	Protein conserved in bacteria
G9272_RS15755	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G9272_RS15770	COG4948	Mandelate Racemase Muconate Lactonizing
G9272_RS15775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G9272_RS15790	COG3250	beta-galactosidase activity
G9272_RS15790	COG5297	Belongs to the glycosyl hydrolase family 6
G9272_RS15815	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G9272_RS15820	COG1234	tRNA 3'-trailer cleavage
G9272_RS15825	COG0537	adenosine 5'-monophosphoramidase activity
G9272_RS15830	COG4946	Tricorn protease homolog
G9272_RS15830	COG0793	Belongs to the peptidase S41A family
G9272_RS15855	COG2070	2-Nitropropane dioxygenase
G9272_RS15860	COG0484	heat shock protein binding
G9272_RS15865	COG1420	regulation of RNA biosynthetic process
G9272_RS15900	COG0481	GTPase activity
G9272_RS15905	COG0268	Binds directly to 16S ribosomal RNA
G9272_RS15935	COG1307	EDD domain protein, DegV family
G9272_RS15945	COG0495	leucyl-tRNA aminoacylation
G9272_RS15955	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G9272_RS15970	COG0477	Major facilitator Superfamily
G9272_RS15985	COG0588	phosphoglycerate mutase activity
G9272_RS15990	COG0799	negative regulation of ribosome biogenesis
G9272_RS16000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G9272_RS16015	COG0501	Belongs to the peptidase M48B family
G9272_RS16030	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G9272_RS16040	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G9272_RS16050	COG1216	Glycosyl transferase, family 2
G9272_RS16070	COG3540	Alkaline phosphatase
G9272_RS16080	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G9272_RS16085	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G9272_RS16090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G9272_RS16180	COG0673	inositol 2-dehydrogenase activity
G9272_RS16185	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G9272_RS16190	COG1530	ribonuclease E activity
G9272_RS16225	COG0772	Belongs to the SEDS family
G9272_RS16230	COG0768	penicillin binding
G9272_RS16245	COG1077	Cell shape determining protein MreB Mrl
G9272_RS16250	COG0105	UTP biosynthetic process
G9272_RS16260	COG0285	dihydrofolate synthase activity
G9272_RS16265	COG0525	valine-tRNA ligase activity
G9272_RS16275	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G9272_RS16280	COG0740	serine-type endopeptidase activity
G9272_RS16285	COG0740	serine-type endopeptidase activity
G9272_RS16290	COG0544	peptidyl-prolyl cis-trans isomerase activity
G9272_RS16310	COG3594	Acyltransferase
G9272_RS16325	COG4552	Acetyltransferase involved in intracellular survival and related
G9272_RS16340	COG1113	amino acid transport
G9272_RS16345	COG0515	serine threonine protein kinase
G9272_RS16360	COG1940	carbohydrate kinase activity
G9272_RS16370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G9272_RS16375	COG1116	anion transmembrane transporter activity
G9272_RS16380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS16390	COG1113	amino acid transport
G9272_RS16395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G9272_RS16410	COG4585	Histidine kinase
G9272_RS16415	COG2197	response regulator
G9272_RS16425	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G9272_RS16505	COG0697	spore germination
G9272_RS16510	COG1846	Transcriptional regulator
G9272_RS16540	COG0668	transmembrane transport
G9272_RS16545	COG1940	carbohydrate kinase activity
G9272_RS16550	COG1653	transport
G9272_RS16555	COG1175	transmembrane transport
G9272_RS16560	COG0395	ABC-type sugar transport system, permease component
G9272_RS16565	COG1486	melibiose metabolic process
G9272_RS16580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9272_RS16610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G9272_RS16655	COG0629	single-stranded DNA binding
G9272_RS16900	COG2188	Transcriptional regulator
G9272_RS16950	COG2304	oxidoreductase activity
G9272_RS17000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G9272_RS17010	COG0728	peptidoglycan biosynthetic process
G9272_RS17110	COG3962	Belongs to the TPP enzyme family
G9272_RS17115	COG3718	enzyme involved in inositol metabolism
G9272_RS17125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9272_RS17155	COG2409	Drug exporters of the RND superfamily
G9272_RS17180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G9272_RS17190	COG1129	ABC transporter
G9272_RS17200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9272_RS17205	COG1869	D-ribose catabolic process
G9272_RS17225	COG0673	inositol 2-dehydrogenase activity
G9272_RS17230	COG1609	Transcriptional regulator
G9272_RS17265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G9272_RS17280	COG1472	Belongs to the glycosyl hydrolase 3 family
G9272_RS17290	COG1609	Transcriptional regulator
G9272_RS17295	COG0395	ABC-type sugar transport system, permease component
G9272_RS17300	COG1175	transmembrane transport
G9272_RS17340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G9272_RS17345	COG2356	endonuclease I
G9272_RS17360	COG0028	Belongs to the TPP enzyme family
G9272_RS17370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9272_RS17385	COG1946	Acyl-CoA thioesterase
G9272_RS17395	COG1309	transcriptional regulator
G9272_RS17400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G9272_RS17415	COG1960	acyl-CoA dehydrogenase activity
G9272_RS17430	COG0076	glutamate decarboxylase activity
G9272_RS17435	COG3486	L-lysine 6-monooxygenase (NADPH) activity
G9272_RS17465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G9272_RS17475	COG0589	response to stress
G9272_RS17485	COG4977	sequence-specific DNA binding
G9272_RS17490	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G9272_RS17520	COG0395	ABC-type sugar transport system, permease component
G9272_RS17540	COG3345	alpha-galactosidase
G9272_RS17545	COG0395	ABC-type sugar transport system, permease component
G9272_RS17550	COG1175	transmembrane transport
G9272_RS17555	COG1653	transport
G9272_RS17560	COG3979	chitinase
G9272_RS17570	COG0745	RESPONSE REGULATOR receiver
G9272_RS17580	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G9272_RS17595	COG0406	alpha-ribazole phosphatase activity
G9272_RS17645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS17670	COG0154	amidase activity
G9272_RS17680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9272_RS17685	COG0765	amino acid transport
G9272_RS17690	COG0765	amino acid transport
G9272_RS17695	COG1126	abc transporter atp-binding protein
G9272_RS17710	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS17720	COG3397	chitin binding
G9272_RS17780	COG0673	inositol 2-dehydrogenase activity
G9272_RS17785	COG4702	Belongs to the UPF0303 family
G9272_RS17815	COG1725	Transcriptional regulator
G9272_RS17825	COG3764	Sortase (surface protein transpeptidase)
G9272_RS17855	COG0270	DNA (cytosine-5-)-methyltransferase activity
G9272_RS17880	COG1074	ATP-dependent DNA helicase activity
G9272_RS17995	COG2733	membrane
G9272_RS18010	COG4555	ABC transporter
G9272_RS18025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G9272_RS18055	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G9272_RS18065	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G9272_RS18070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9272_RS18075	COG1263	PTS System
G9272_RS18080	COG1263	PTS System
G9272_RS18110	COG1335	isochorismatase
G9272_RS18120	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G9272_RS18130	COG1113	amino acid transport
G9272_RS18170	COG0277	FAD linked oxidase domain protein
G9272_RS18180	COG3185	4-Hydroxyphenylpyruvate dioxygenase
G9272_RS18190	COG1174	glycine betaine transport
G9272_RS18200	COG1174	glycine betaine transport
G9272_RS18225	COG3654	unkown
G9272_RS18295	COG3525	Glycosyl hydrolase, family 20, catalytic domain
G9272_RS18300	COG0395	ABC-type sugar transport system, permease component
G9272_RS18305	COG1175	transmembrane transport
G9272_RS18320	COG1678	Uncharacterized ACR, COG1678
G9272_RS18325	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G9272_RS18330	COG0776	regulation of translation
G9272_RS18340	COG3973	AAA domain
G9272_RS18365	COG2223	nitrite transmembrane transporter activity
G9272_RS18385	COG1653	transport
G9272_RS18390	COG1175	transmembrane transport
G9272_RS18395	COG0395	ABC-type sugar transport system, permease component
G9272_RS18400	COG1501	Belongs to the glycosyl hydrolase 31 family
G9272_RS18420	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G9272_RS18425	COG0793	Belongs to the peptidase S41A family
G9272_RS18435	COG2884	Cell division ATP-binding protein ftsE
G9272_RS18450	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G9272_RS18455	COG0515	serine threonine protein kinase
G9272_RS18460	COG0515	serine threonine protein kinase
G9272_RS18470	COG1653	transport
G9272_RS18475	COG1175	transmembrane transport
G9272_RS18480	COG0395	ABC-type sugar transport system, permease component
G9272_RS18485	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G9272_RS18490	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G9272_RS18510	COG1764	response to oxidative stress
G9272_RS18515	COG1846	Transcriptional regulator
G9272_RS18530	COG2197	response regulator
G9272_RS18545	COG1134	teichoic acid transport
G9272_RS18550	COG2902	Dehydrogenase
G9272_RS18575	COG0653	protein targeting
G9272_RS18585	COG3214	Protein conserved in bacteria
G9272_RS18590	COG2197	response regulator
G9272_RS18595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G9272_RS18605	COG0823	Involved in the tonB-independent uptake of proteins
G9272_RS18610	COG5002	protein histidine kinase activity
G9272_RS18615	COG0745	RESPONSE REGULATOR receiver
G9272_RS18625	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
G9272_RS18645	COG0714	Associated with various cellular activities
G9272_RS18685	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G9272_RS18695	COG1482	cell wall glycoprotein biosynthetic process
G9272_RS18705	COG2835	tetraacyldisaccharide 4'-kinase activity
G9272_RS18710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G9272_RS18750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G9272_RS18755	COG0778	Nitroreductase
G9272_RS18755	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G9272_RS18780	COG1316	TRANSCRIPTIONal
G9272_RS18785	COG1316	TRANSCRIPTIONal
G9272_RS18790	COG1316	TRANSCRIPTIONal
G9272_RS18800	COG1316	TRANSCRIPTIONal
G9272_RS18810	COG1316	TRANSCRIPTIONal
G9272_RS18825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G9272_RS18850	COG0789	Transcriptional regulator
G9272_RS18855	COG1902	pentaerythritol trinitrate reductase activity
G9272_RS18865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G9272_RS18880	COG2205	protein histidine kinase activity
G9272_RS18885	COG0745	RESPONSE REGULATOR receiver
G9272_RS18890	COG3104	oligopeptide transport
G9272_RS18920	COG1366	Belongs to the anti-sigma-factor antagonist family
G9272_RS18925	COG1191	sigma factor activity
G9272_RS18940	COG1228	amidohydrolase
G9272_RS18955	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G9272_RS18990	COG2986	histidine ammonia-lyase
G9272_RS19000	COG1174	glycine betaine transport
G9272_RS19005	COG1174	glycine betaine transport
G9272_RS19020	COG4221	oxidoreductase activity
G9272_RS19035	COG2755	lipolytic protein G-D-S-L family
G9272_RS19040	COG0183	Belongs to the thiolase family
G9272_RS19075	COG1136	(ABC) transporter
G9272_RS19080	COG0577	efflux transmembrane transporter activity
G9272_RS19085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G9272_RS19090	COG1252	NADH dehydrogenase
G9272_RS19110	COG0148	phosphopyruvate hydratase activity
G9272_RS19185	COG0577	efflux transmembrane transporter activity
G9272_RS19190	COG1136	(ABC) transporter
G9272_RS19195	COG0477	Major facilitator Superfamily
G9272_RS19205	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9272_RS19215	COG0667	Aldo Keto reductase
G9272_RS19250	COG4585	Histidine kinase
G9272_RS19260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G9272_RS19265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G9272_RS19270	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G9272_RS19275	COG0193	aminoacyl-tRNA hydrolase activity
G9272_RS19285	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G9272_RS19295	COG1309	transcriptional regulator
G9272_RS19310	COG4106	trans-aconitate 2-methyltransferase activity
G9272_RS19315	COG1846	Transcriptional regulator
G9272_RS19320	COG2197	response regulator
G9272_RS19330	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G9272_RS19405	COG0488	(ABC) transporter
G9272_RS19415	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G9272_RS19420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G9272_RS19430	COG0084	hydrolase, TatD family'
G9272_RS19465	COG0310	cobalt ion transport
G9272_RS19475	COG1122	ATPase activity
G9272_RS19480	COG1846	Transcriptional regulator
G9272_RS19485	COG1764	response to oxidative stress
G9272_RS19510	COG0442	prolyl-tRNA aminoacylation
G9272_RS19515	COG2409	Drug exporters of the RND superfamily
G9272_RS19525	COG4946	Tricorn protease homolog
G9272_RS19525	COG0793	Belongs to the peptidase S41A family
G9272_RS19535	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS19540	COG2267	carboxylic ester hydrolase activity
G9272_RS19545	COG2072	flavoprotein involved in K transport
G9272_RS19565	COG2197	response regulator
G9272_RS19580	COG0577	efflux transmembrane transporter activity
G9272_RS19595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9272_RS19600	COG0315	cyclic pyranopterin monophosphate synthase activity
G9272_RS19600	COG0521	Mo-molybdopterin cofactor biosynthetic process
G9272_RS19605	COG0315	cyclic pyranopterin monophosphate synthase activity
G9272_RS19615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G9272_RS19620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G9272_RS19645	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G9272_RS19655	COG1970	mechanosensitive ion channel activity
G9272_RS19670	COG3191	aminopeptidase activity
G9272_RS19675	COG1376	ErfK ybiS ycfS ynhG family protein
G9272_RS19690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9272_RS19690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9272_RS19700	COG1349	DNA-binding transcription factor activity
G9272_RS19705	COG0477	Major facilitator Superfamily
G9272_RS19725	COG1247	-acetyltransferase
G9272_RS19730	COG3384	dioxygenase
G9272_RS19735	COG1846	Transcriptional regulator
G9272_RS19755	COG1414	Transcriptional regulator
G9272_RS19880	COG1302	Protein conserved in bacteria
G9272_RS19905	COG1595	DNA-templated transcription, initiation
G9272_RS19920	COG4585	Histidine kinase
G9272_RS19925	COG1136	(ABC) transporter
G9272_RS19925	COG0577	efflux transmembrane transporter activity
G9272_RS19935	COG3594	Acyltransferase
G9272_RS19955	COG1846	Transcriptional regulator
G9272_RS19970	COG0386	Belongs to the glutathione peroxidase family
G9272_RS19995	COG1686	Belongs to the peptidase S11 family
G9272_RS20035	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G9272_RS20155	COG3903	Transcriptional regulator
G9272_RS20155	COG3629	intracellular signal transduction
G9272_RS20180	COG1024	Enoyl-CoA hydratase
G9272_RS20210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9272_RS20210	COG0515	serine threonine protein kinase
G9272_RS20220	COG1309	transcriptional regulator
G9272_RS20225	COG1522	sequence-specific DNA binding
G9272_RS20230	COG1280	lysine exporter protein (LysE YggA)
G9272_RS20240	COG1960	acyl-CoA dehydrogenase activity
G9272_RS20265	COG0259	pyridoxamine-phosphate oxidase activity
G9272_RS20290	COG2072	flavoprotein involved in K transport
G9272_RS20295	COG1231	oxidoreductase activity
G9272_RS20305	COG1024	Enoyl-CoA hydratase
G9272_RS20320	COG2814	Major facilitator Superfamily
G9272_RS20340	COG1960	acyl-CoA dehydrogenase activity
G9272_RS20345	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS20360	COG1960	acyl-CoA dehydrogenase activity
G9272_RS20365	COG1960	acyl-CoA dehydrogenase activity
G9272_RS20385	COG1366	Belongs to the anti-sigma-factor antagonist family
G9272_RS20430	COG1131	(ABC) transporter
G9272_RS20440	COG0596	Alpha beta hydrolase
G9272_RS20450	COG4821	SIS domain
G9272_RS20475	COG0259	pyridoxamine-phosphate oxidase activity
G9272_RS20490	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS20505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G9272_RS20525	COG5006	permease, DMT superfamily
G9272_RS20535	COG0277	FAD linked oxidase domain protein
G9272_RS20540	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G9272_RS20545	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G9272_RS20560	COG0667	Aldo Keto reductase
G9272_RS20600	COG2252	PERMEase
G9272_RS20610	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G9272_RS20640	COG2814	Major facilitator Superfamily
G9272_RS20650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G9272_RS20655	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
G9272_RS20690	COG1061	Type III restriction enzyme res subunit
G9272_RS20700	COG3973	AAA domain
G9272_RS20730	COG1737	Transcriptional regulator
G9272_RS20735	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G9272_RS20740	COG1263	PTS System
G9272_RS20740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9272_RS20755	COG0477	Major facilitator Superfamily
G9272_RS20760	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G9272_RS20810	COG0459	protein refolding
G9272_RS20830	COG0463	Glycosyl transferase, family 2
G9272_RS20835	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G9272_RS20865	COG1105	Belongs to the carbohydrate kinase PfkB family
G9272_RS20875	COG3300	MHYT domain
G9272_RS20875	COG5001	Diguanylate cyclase
G9272_RS20895	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G9272_RS20955	COG3842	ATPase activity
G9272_RS20965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G9272_RS20980	COG0215	cysteine-tRNA ligase activity
G9272_RS20985	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G9272_RS20990	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G9272_RS20995	COG1329	Transcriptional regulator
G9272_RS21010	COG5002	protein histidine kinase activity
G9272_RS21075	COG0588	phosphoglycerate mutase activity
G9272_RS21105	COG0438	transferase activity, transferring glycosyl groups
G9272_RS21165	COG2186	Transcriptional regulator
G9272_RS21175	COG2188	Transcriptional regulator
G9272_RS21180	COG4552	Acetyltransferase involved in intracellular survival and related
G9272_RS21190	COG1490	D-aminoacyl-tRNA deacylase activity
G9272_RS21195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G9272_RS21205	COG3485	protocatechuate 3,4-dioxygenase
G9272_RS21240	COG2897	thiosulfate sulfurtransferase activity
G9272_RS21265	COG0745	RESPONSE REGULATOR receiver
G9272_RS21270	COG1609	Transcriptional regulator
G9272_RS21275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G9272_RS21285	COG0745	RESPONSE REGULATOR receiver
G9272_RS21290	COG2205	protein histidine kinase activity
G9272_RS21290	COG2972	Histidine kinase
G9272_RS21300	COG0745	RESPONSE REGULATOR receiver
G9272_RS21305	COG1132	(ABC) transporter
G9272_RS21310	COG0737	Belongs to the 5'-nucleotidase family
G9272_RS21315	COG0456	acetyltransferase
G9272_RS21330	COG1131	(ABC) transporter
G9272_RS21345	COG1725	Transcriptional regulator
G9272_RS21350	COG1131	(ABC) transporter
G9272_RS21365	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G9272_RS21375	COG0406	alpha-ribazole phosphatase activity
G9272_RS21375	COG0494	nUDIX hydrolase
G9272_RS21395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G9272_RS21400	COG0306	phosphate transporter
G9272_RS21410	COG1937	Protein conserved in bacteria
G9272_RS21430	COG0277	FAD linked oxidase domain protein
G9272_RS21435	COG0671	phosphoesterase, PA-phosphatase related
G9272_RS21440	COG1196	nuclear chromosome segregation
G9272_RS21440	COG0741	lytic transglycosylase activity
G9272_RS21440	COG0739	heme binding
G9272_RS21465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G9272_RS21545	COG1252	NADH dehydrogenase
G9272_RS21575	COG0579	oxidoreductase
G9272_RS21580	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G9272_RS21590	COG0667	Aldo Keto reductase
G9272_RS21605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G9272_RS21605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G9272_RS21615	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G9272_RS21620	COG0494	nUDIX hydrolase
G9272_RS21630	COG1349	DNA-binding transcription factor activity
G9272_RS21665	COG0513	Belongs to the DEAD box helicase family
G9272_RS21700	COG1643	Atp-dependent helicase
G9272_RS21720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G9272_RS21730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G9272_RS21750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G9272_RS21755	COG0047	phosphoribosylformylglycinamidine synthase activity
G9272_RS21760	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G9272_RS21790	COG3851	Histidine kinase
G9272_RS21795	COG2197	response regulator
G9272_RS21805	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G9272_RS21825	COG0151	Belongs to the GarS family
G9272_RS21875	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS21910	COG0433	COG0433 Predicted ATPase
G9272_RS21925	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G9272_RS21970	COG1191	sigma factor activity
G9272_RS21975	COG1191	sigma factor activity
G9272_RS21995	COG0477	Major facilitator Superfamily
G9272_RS22000	COG2353	YceI-like domain
G9272_RS22005	COG3467	pyridoxamine 5'-phosphate
G9272_RS22015	COG0477	Major facilitator Superfamily
G9272_RS22020	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G9272_RS22030	COG2205	protein histidine kinase activity
G9272_RS22035	COG0745	RESPONSE REGULATOR receiver
G9272_RS22040	COG2329	Antibiotic biosynthesis monooxygenase
G9272_RS22055	COG1846	Transcriptional regulator
G9272_RS22090	COG1309	transcriptional regulator
G9272_RS22095	COG2814	Major facilitator Superfamily
G9272_RS22100	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS22105	COG1595	DNA-templated transcription, initiation
G9272_RS22170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G9272_RS22185	COG0653	protein targeting
G9272_RS22205	COG0006	proline dipeptidase activity
G9272_RS22220	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
G9272_RS22245	COG1999	signal sequence binding
G9272_RS22260	COG2837	iron assimilation
G9272_RS22270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G9272_RS22275	COG0561	phosphatase activity
G9272_RS22325	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
G9272_RS22340	COG0561	phosphatase activity
G9272_RS22345	COG2207	Transcriptional regulator
G9272_RS22345	COG3708	Transcriptional regulator
G9272_RS22350	COG0741	lytic transglycosylase activity
G9272_RS22350	COG0739	heme binding
G9272_RS22350	COG1196	nuclear chromosome segregation
G9272_RS22355	COG4988	ABC transporter
G9272_RS22360	COG1294	oxidase, subunit
G9272_RS22365	COG1271	oxidase subunit
G9272_RS22370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G9272_RS22375	COG1609	Transcriptional regulator
G9272_RS22395	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G9272_RS22420	COG0662	Cupin 2, conserved barrel domain protein
G9272_RS22425	COG1950	PFAM Membrane protein of
G9272_RS22430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G9272_RS22435	COG0626	cystathionine gamma-synthase activity
G9272_RS22470	COG2814	Major facilitator Superfamily
G9272_RS22500	COG0305	Participates in initiation and elongation during chromosome replication
G9272_RS22510	COG0359	binds to the 23S rRNA
G9272_RS22515	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G9272_RS22520	COG0629	single-stranded DNA binding
G9272_RS22525	COG0360	Binds together with S18 to 16S ribosomal RNA
G9272_RS22550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G9272_RS22575	COG0617	tRNA 3'-terminal CCA addition
G9272_RS22590	COG2815	serine threonine protein kinase
G9272_RS22590	COG0515	serine threonine protein kinase
G9272_RS22595	COG1595	DNA-templated transcription, initiation
G9272_RS22605	COG0492	ferredoxin-NADP+ reductase activity
G9272_RS22610	COG3118	belongs to the thioredoxin family
G9272_RS22625	COG1192	Involved in chromosome partitioning
G9272_RS22630	COG0357	Ribosomal RNA small subunit methyltransferase G
G9272_RS22640	COG0706	membrane insertase activity
G9272_RS22645	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G9272_RS22650	COG0594	ribonuclease P activity
G9272_RS22655	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G9272_RS22660	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G9272_RS22665	COG0592	DNA-directed DNA polymerase activity
G9272_RS22670	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G9272_RS22675	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G9272_RS22680	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
G9272_RS22685	COG0187	DNA topoisomerase II activity
G9272_RS22690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G9272_RS22750	COG0705	Rhomboid family
G9272_RS22765	COG3764	Sortase (surface protein transpeptidase)
G9272_RS22780	COG3764	Sortase (surface protein transpeptidase)
G9272_RS22785	COG3764	Sortase (surface protein transpeptidase)
G9272_RS22790	COG0515	serine threonine protein kinase
G9272_RS22795	COG0768	penicillin binding
G9272_RS22810	COG1716	ATPase activity
G9272_RS22815	COG1716	ATPase activity
G9272_RS22845	COG1960	acyl-CoA dehydrogenase activity
G9272_RS22850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9272_RS22855	COG2151	metal-sulfur cluster biosynthetic enzyme
G9272_RS22860	COG3396	Phenylacetate-CoA oxygenase
G9272_RS22865	COG3460	Phenylacetate-CoA oxygenase
G9272_RS22870	COG3396	Phenylacetate-CoA oxygenase
G9272_RS22895	COG1250	3-hydroxyacyl-CoA dehydrogenase
G9272_RS22900	COG1309	transcriptional regulator
G9272_RS22905	COG1522	sequence-specific DNA binding
G9272_RS22955	COG0604	alcohol dehydrogenase
G9272_RS22955	COG3321	synthase
G9272_RS22955	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS22970	COG0515	serine threonine protein kinase
G9272_RS22975	COG0515	serine threonine protein kinase
G9272_RS22980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G9272_RS22990	COG0022	dehydrogenase e1 component
G9272_RS22995	COG0508	dehydrogenase complex catalyzes the overall conversion of
G9272_RS23070	COG1362	aminopeptidase activity
G9272_RS23075	COG1960	acyl-CoA dehydrogenase activity
G9272_RS23085	COG1741	Belongs to the pirin family
G9272_RS23105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G9272_RS23165	COG3866	Pectate lyase
G9272_RS23175	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9272_RS23190	COG1289	transmembrane transporter activity
G9272_RS23195	COG3021	interspecies interaction between organisms
G9272_RS23205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9272_RS23245	COG0701	Predicted permease
G9272_RS23265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G9272_RS23280	COG0366	Alpha amylase catalytic
G9272_RS23290	COG4122	O-methyltransferase activity
G9272_RS23385	COG1316	TRANSCRIPTIONal
G9272_RS23390	COG4585	Histidine kinase
G9272_RS23410	COG1595	DNA-templated transcription, initiation
G9272_RS23505	COG0464	growth
G9272_RS23540	COG0513	Belongs to the DEAD box helicase family
G9272_RS23545	COG1278	Cold shock
G9272_RS23580	COG3467	pyridoxamine 5'-phosphate
G9272_RS23630	COG2197	response regulator
G9272_RS23660	COG1278	Cold shock
G9272_RS23675	COG4214	carbohydrate transport
G9272_RS23685	COG4213	ABC transporter substrate-binding protein
G9272_RS23695	COG0726	polysaccharide deacetylase
G9272_RS23705	COG2197	response regulator
G9272_RS23710	COG2197	response regulator
G9272_RS23725	COG0577	efflux transmembrane transporter activity
G9272_RS23725	COG1136	(ABC) transporter
G9272_RS23755	COG0723	plastoquinol--plastocyanin reductase activity
G9272_RS23755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9272_RS23775	COG1295	ribonuclease BN
G9272_RS23845	COG1131	(ABC) transporter
G9272_RS23855	COG4585	Histidine kinase
G9272_RS23860	COG2197	response regulator
G9272_RS23925	COG0717	Belongs to the dCTP deaminase family
G9272_RS23930	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G9272_RS23945	COG2181	nitrate reductase activity
G9272_RS23945	COG0247	lactate metabolic process
G9272_RS23950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G9272_RS23955	COG0443	Heat shock 70 kDa protein
G9272_RS23960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G9272_RS23965	COG0484	heat shock protein binding
G9272_RS23970	COG0789	Transcriptional regulator
G9272_RS24090	COG4213	ABC transporter substrate-binding protein
G9272_RS24095	COG1305	Transglutaminase-like
G9272_RS24135	COG0542	response to heat
G9272_RS24180	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G9272_RS24195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G9272_RS24200	COG0191	fructose-bisphosphate aldolase activity
G9272_RS24205	COG0477	Major facilitator Superfamily
G9272_RS24215	COG3483	tryptophan 2,3-dioxygenase activity
G9272_RS24220	COG3844	kynureninase activity
G9272_RS24240	COG4585	Histidine kinase
G9272_RS24245	COG2197	response regulator
G9272_RS24250	COG4585	Histidine kinase
G9272_RS24255	COG2197	response regulator
G9272_RS24275	COG3559	Exporter of polyketide antibiotics
G9272_RS24280	COG1131	(ABC) transporter
G9272_RS24295	COG4303	Ethanolamine ammonia lyase large subunit
G9272_RS24310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G9272_RS24315	COG0737	Belongs to the 5'-nucleotidase family
G9272_RS24330	COG0463	Glycosyl transferase, family 2
G9272_RS24335	COG1802	Transcriptional regulator
G9272_RS24340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G9272_RS24345	COG0693	protein deglycase activity
G9272_RS24360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G9272_RS24370	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G9272_RS24375	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G9272_RS24395	COG2205	protein histidine kinase activity
G9272_RS24415	COG1595	DNA-templated transcription, initiation
G9272_RS24440	COG0701	Predicted permease
G9272_RS24455	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G9272_RS24485	COG2319	Wd-40 repeat
G9272_RS24485	COG4249	Peptidase C14 caspase catalytic subunit p20
G9272_RS24490	COG0477	Major facilitator Superfamily
G9272_RS24505	COG1309	transcriptional regulator
G9272_RS24510	COG2910	NAD(P)H-binding
G9272_RS24520	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G9272_RS24535	COG1302	Protein conserved in bacteria
G9272_RS24555	COG2205	protein histidine kinase activity
G9272_RS24575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G9272_RS24610	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
G9272_RS24655	COG4191	Histidine kinase
G9272_RS24670	COG0494	nUDIX hydrolase
G9272_RS24685	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
G9272_RS24695	COG0406	alpha-ribazole phosphatase activity
G9272_RS24700	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G9272_RS24805	COG1408	metallophosphoesterase
G9272_RS24815	COG4499	WXG100 protein secretion system (Wss), protein YukC
G9272_RS24815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G9272_RS24825	COG0003	Pfam Anion-transporting ATPase
G9272_RS24850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G9272_RS24880	COG2267	carboxylic ester hydrolase activity
G9272_RS24890	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G9272_RS24895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G9272_RS24900	COG0288	reversible hydration of carbon dioxide
G9272_RS24960	COG1205	dead DEAH box helicase
G9272_RS24960	COG1111	helicase
G9272_RS24965	COG1366	Belongs to the anti-sigma-factor antagonist family
G9272_RS24970	COG2172	sigma factor antagonist activity
G9272_RS24975	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G9272_RS24995	COG1754	DNA topoisomerase type I activity
G9272_RS24995	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G9272_RS25000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G9272_RS25050	COG0270	DNA (cytosine-5-)-methyltransferase activity
G9272_RS25210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G9272_RS25235	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G9272_RS25235	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G9272_RS25260	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G9272_RS25265	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G9272_RS25270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G9272_RS25275	COG0254	rRNA binding
G9272_RS25285	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G9272_RS25305	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS25325	COG0076	glutamate decarboxylase activity
G9272_RS25335	COG0789	Transcriptional regulator
G9272_RS25340	COG0393	Putative heavy-metal-binding
G9272_RS25355	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G9272_RS25360	COG2027	D-alanyl-D-alanine carboxypeptidase
G9272_RS25370	COG0037	tRNA processing
G9272_RS25385	COG0302	gtp cyclohydrolase
G9272_RS25400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G9272_RS25415	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G9272_RS25415	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G9272_RS25440	COG0649	NAD binding
G9272_RS25455	COG2197	response regulator
G9272_RS25460	COG0640	Transcriptional regulator
G9272_RS25480	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G9272_RS25485	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G9272_RS25495	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G9272_RS25515	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G9272_RS25540	COG0739	heme binding
G9272_RS25550	COG0477	Major facilitator Superfamily
G9272_RS25555	COG2205	protein histidine kinase activity
G9272_RS25560	COG0745	RESPONSE REGULATOR receiver
G9272_RS25570	COG1595	DNA-templated transcription, initiation
G9272_RS25575	COG1194	a g-specific adenine glycosylase
G9272_RS25585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
G9272_RS25605	COG0248	Ppx GppA phosphatase
G9272_RS25610	COG1082	Xylose isomerase domain protein TIM barrel
G9272_RS25615	COG1309	transcriptional regulator
G9272_RS25620	COG0129	dihydroxy-acid dehydratase activity
G9272_RS25630	COG4991	sh3 domain protein
G9272_RS25645	COG0659	secondary active sulfate transmembrane transporter activity
G9272_RS25650	COG1129	ABC transporter
G9272_RS25650	COG0842	Transport permease protein
G9272_RS25660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G9272_RS25675	COG0180	Tryptophanyl-tRNA synthetase
G9272_RS25695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9272_RS25705	COG0738	Major facilitator superfamily
G9272_RS25710	COG0123	including yeast histone deacetylase and acetoin utilization protein
G9272_RS25770	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
G9272_RS25775	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G9272_RS25780	COG0181	hydroxymethylbilane synthase activity
G9272_RS25785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G9272_RS25785	COG1648	precorrin-2 dehydrogenase activity
G9272_RS25795	COG0113	porphobilinogen synthase activity
G9272_RS25820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9272_RS25840	COG0018	arginyl-trna synthetase
G9272_RS25845	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
G9272_RS25865	COG1690	Belongs to the RtcB family
G9272_RS25885	COG1742	UPF0060 membrane protein
G9272_RS25895	COG1846	Transcriptional regulator
G9272_RS25910	COG1733	regulation of RNA biosynthetic process
G9272_RS25925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS25940	COG2205	protein histidine kinase activity
G9272_RS25965	COG0477	Major facilitator Superfamily
G9272_RS26000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G9272_RS26005	COG0406	alpha-ribazole phosphatase activity
G9272_RS26015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G9272_RS26020	COG0785	Cytochrome C biogenesis protein
G9272_RS26025	COG1333	cytochrome c biogenesis protein
G9272_RS26030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G9272_RS26060	COG1404	Belongs to the peptidase S8 family
G9272_RS26070	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G9272_RS26080	COG0163	prenyltransferase activity
G9272_RS26090	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G9272_RS26105	COG1309	transcriptional regulator
G9272_RS26120	COG0183	Belongs to the thiolase family
G9272_RS26180	COG1053	succinate dehydrogenase
G9272_RS26185	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
G9272_RS26200	COG0596	Alpha beta hydrolase
G9272_RS26205	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G9272_RS26210	COG1278	Cold shock
G9272_RS26215	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
G9272_RS26235	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G9272_RS26255	COG1215	transferase activity, transferring glycosyl groups
G9272_RS26265	COG2226	methyltransferase
G9272_RS26295	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9272_RS26300	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9272_RS26305	COG0649	NAD binding
G9272_RS26315	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G9272_RS26320	COG1034	ATP synthesis coupled electron transport
G9272_RS26325	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G9272_RS26330	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9272_RS26340	COG0713	ATP synthesis coupled electron transport
G9272_RS26345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G9272_RS26355	COG1007	ATP synthesis coupled electron transport
G9272_RS26360	COG0514	ATP-dependent DNA helicase (RecQ)
G9272_RS26365	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G9272_RS26370	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G9272_RS26390	COG2188	Transcriptional regulator
G9272_RS26450	COG0561	phosphatase activity
G9272_RS26455	COG3953	SLT domain
G9272_RS26455	COG5412	phage tail tape measure protein
G9272_RS26460	COG0142	geranyltranstransferase activity
G9272_RS26470	COG1131	(ABC) transporter
G9272_RS26480	COG0655	NAD(P)H dehydrogenase (quinone) activity
G9272_RS26515	COG0702	epimerase
G9272_RS26520	COG1733	regulation of RNA biosynthetic process
G9272_RS26525	COG1013	pyruvate-flavodoxin oxidoreductase activity
G9272_RS26530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G9272_RS26530	COG0674	pyruvate-flavodoxin oxidoreductase activity
G9272_RS26550	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9272_RS26555	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9272_RS26560	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9272_RS26565	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G9272_RS26570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9272_RS26575	COG0839	Belongs to the complex I subunit 6 family
G9272_RS26580	COG0713	ATP synthesis coupled electron transport
G9272_RS26595	COG1007	ATP synthesis coupled electron transport
G9272_RS26600	COG0501	Belongs to the peptidase M48B family
G9272_RS26605	COG3304	Inner membrane component domain
G9272_RS26620	COG2261	transglycosylase associated protein
G9272_RS26625	COG1666	GTP binding
G9272_RS26650	COG0702	epimerase
G9272_RS26670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G9272_RS26675	COG2030	dehydratase
G9272_RS26695	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G9272_RS26700	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G9272_RS26705	COG0436	Aminotransferase
G9272_RS26720	COG0250	Participates in transcription elongation, termination and antitermination
G9272_RS26725	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G9272_RS26730	COG0081	regulation of translation
G9272_RS26745	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G9272_RS26750	COG0222	ribosome binding
G9272_RS26755	COG0085	RNA polymerase activity
G9272_RS26760	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G9272_RS26895	COG0463	Glycosyl transferase, family 2
G9272_RS26900	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G9272_RS26905	COG0049	tRNA binding
G9272_RS26910	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G9272_RS26915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G9272_RS26930	COG0051	transcription antitermination factor activity, RNA binding
G9272_RS26935	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G9272_RS26940	COG0088	Forms part of the polypeptide exit tunnel
G9272_RS26945	COG0089	rRNA binding
G9272_RS26950	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G9272_RS26955	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G9272_RS26960	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G9272_RS26965	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G9272_RS26970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G9272_RS26975	COG0255	Belongs to the universal ribosomal protein uL29 family
G9272_RS26980	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G9272_RS26985	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G9272_RS26990	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G9272_RS26995	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G9272_RS27000	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G9272_RS27005	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G9272_RS27010	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G9272_RS27015	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G9272_RS27020	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G9272_RS27025	COG1841	ribosomal large subunit assembly
G9272_RS27030	COG0200	Binds to the 23S rRNA
G9272_RS27040	COG0563	adenylate kinase activity
G9272_RS27050	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G9272_RS27055	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G9272_RS27060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G9272_RS27065	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G9272_RS27070	COG0202	RNA polymerase activity
G9272_RS27075	COG0203	ribosomal protein L17
G9272_RS27080	COG0101	tRNA pseudouridine synthase activity
G9272_RS27090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G9272_RS27095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G9272_RS27100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G9272_RS27110	COG1072	(Pantothenic acid kinase))
G9272_RS27115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G9272_RS27130	COG0736	holo-[acyl-carrier-protein] synthase activity
G9272_RS27145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G9272_RS27155	COG0802	atpase or kinase
G9272_RS27180	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G9272_RS27210	COG1609	Transcriptional regulator
G9272_RS27220	COG1316	TRANSCRIPTIONal
G9272_RS27240	COG4941	Belongs to the sigma-70 factor family
G9272_RS27255	COG0726	polysaccharide deacetylase
G9272_RS27260	COG0726	polysaccharide deacetylase
G9272_RS27265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G9272_RS27270	COG0459	protein refolding
G9272_RS27280	COG4221	oxidoreductase activity
G9272_RS27290	COG0583	DNA-binding transcription factor activity
G9272_RS27305	COG1595	DNA-templated transcription, initiation
G9272_RS27315	COG0516	GMP reductase activity
G9272_RS27325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G9272_RS27340	COG0515	serine threonine protein kinase
G9272_RS27340	COG2815	serine threonine protein kinase
G9272_RS27345	COG2815	serine threonine protein kinase
G9272_RS27345	COG0515	serine threonine protein kinase
G9272_RS27350	COG0515	serine threonine protein kinase
G9272_RS27355	COG0515	serine threonine protein kinase
G9272_RS27360	COG0515	serine threonine protein kinase
G9272_RS27365	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS27390	COG0519	Catalyzes the synthesis of GMP from XMP
G9272_RS27390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G9272_RS27440	COG2197	response regulator
G9272_RS27470	COG0739	heme binding
G9272_RS27480	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G9272_RS27480	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G9272_RS27495	COG0714	Associated with various cellular activities
G9272_RS27500	COG2425	protein containing a von Willebrand factor type A (vWA) domain
G9272_RS27505	COG3552	Protein containing von Willebrand factor type A (VWA) domain
G9272_RS27515	COG0045	succinate-CoA ligase (ADP-forming) activity
G9272_RS27545	COG0138	bifunctional purine biosynthesis protein purh
G9272_RS27555	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G9272_RS27575	COG0039	L-malate dehydrogenase activity
G9272_RS27590	COG0477	Major facilitator Superfamily
G9272_RS27605	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS27615	COG4175	Glycine betaine
G9272_RS27615	COG0517	IMP dehydrogenase activity
G9272_RS27620	COG4176	ABC-type proline glycine betaine transport system permease component
G9272_RS27635	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9272_RS27640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9272_RS27645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9272_RS27650	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9272_RS27660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9272_RS27665	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS27670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G9272_RS27675	COG0512	Glutamine amidotransferase of anthranilate synthase
G9272_RS27675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G9272_RS27680	COG3224	Antibiotic biosynthesis monooxygenase
G9272_RS27700	COG0754	glutathionylspermidine amidase activity
G9272_RS27705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G9272_RS27710	COG0180	Tryptophanyl-tRNA synthetase
G9272_RS27730	COG0671	phosphoesterase, PA-phosphatase related
G9272_RS27740	COG1295	ribonuclease BN
G9272_RS27745	COG1686	Belongs to the peptidase S11 family
G9272_RS27755	COG1408	metallophosphoesterase
G9272_RS27770	COG2205	protein histidine kinase activity
G9272_RS27775	COG0745	RESPONSE REGULATOR receiver
G9272_RS27780	COG2409	Drug exporters of the RND superfamily
G9272_RS27825	COG1053	succinate dehydrogenase
G9272_RS27835	COG2009	succinate dehydrogenase
G9272_RS27845	COG3525	Glycosyl hydrolase, family 20, catalytic domain
G9272_RS27870	COG1595	DNA-templated transcription, initiation
G9272_RS27885	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G9272_RS27885	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G9272_RS27905	COG0463	Glycosyl transferase, family 2
G9272_RS27925	COG1216	Glycosyl transferase, family 2
G9272_RS27945	COG1216	Glycosyl transferase, family 2
G9272_RS27960	COG2089	acid synthase
G9272_RS27970	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G9272_RS27970	COG1473	amidohydrolase
G9272_RS27975	COG1744	ABC transporter substrate-binding protein PnrA-like
G9272_RS27980	COG1744	ABC transporter substrate-binding protein PnrA-like
G9272_RS27985	COG3845	ABC transporter
G9272_RS27990	COG4603	Belongs to the binding-protein-dependent transport system permease family
G9272_RS27995	COG1079	Belongs to the binding-protein-dependent transport system permease family
G9272_RS28020	COG0592	DNA-directed DNA polymerase activity
G9272_RS28025	COG2814	Major facilitator Superfamily
G9272_RS28030	COG0583	DNA-binding transcription factor activity
G9272_RS28040	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G9272_RS28065	COG2205	protein histidine kinase activity
G9272_RS28070	COG0745	RESPONSE REGULATOR receiver
G9272_RS28075	COG1595	DNA-templated transcription, initiation
G9272_RS28090	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS28095	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS28100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G9272_RS28115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G9272_RS28145	COG4770	biotin carboxylase activity
G9272_RS28155	COG0424	maF-like protein
G9272_RS28165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G9272_RS28175	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G9272_RS28185	COG1024	Enoyl-CoA hydratase
G9272_RS28195	COG2986	histidine ammonia-lyase
G9272_RS28225	COG1136	(ABC) transporter
G9272_RS28240	COG1064	alcohol dehydrogenase
G9272_RS28245	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9272_RS28250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9272_RS28265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G9272_RS28285	COG0628	permease
G9272_RS28290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G9272_RS28315	COG2255	four-way junction helicase activity
G9272_RS28320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G9272_RS28335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G9272_RS28345	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G9272_RS28355	COG2255	four-way junction helicase activity
G9272_RS28360	COG1331	Highly conserved protein containing a thioredoxin domain
G9272_RS28390	COG1309	transcriptional regulator
G9272_RS28395	COG0477	Major facilitator Superfamily
G9272_RS28405	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G9272_RS28435	COG0436	Aminotransferase
G9272_RS28450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G9272_RS28450	COG2080	2 iron, 2 sulfur cluster binding
G9272_RS28465	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G9272_RS28480	COG1414	Transcriptional regulator
G9272_RS28485	COG0251	oxidation-reduction process
G9272_RS28490	COG2610	gluconate transmembrane transporter activity
G9272_RS28520	COG1595	DNA-templated transcription, initiation
G9272_RS28550	COG2894	cell division
G9272_RS28585	COG2197	response regulator
G9272_RS28615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G9272_RS28620	COG2226	methyltransferase
G9272_RS28625	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G9272_RS28630	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G9272_RS28635	COG0741	lytic transglycosylase activity
G9272_RS28670	COG1136	(ABC) transporter
G9272_RS28690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G9272_RS28700	COG3557	Belongs to the UPF0374 family
G9272_RS28705	COG0114	fumarate hydratase activity
G9272_RS28710	COG1595	DNA-templated transcription, initiation
G9272_RS28740	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
G9272_RS28740	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
G9272_RS28765	COG0778	Nitroreductase
G9272_RS28770	COG1722	exodeoxyribonuclease VII activity
G9272_RS28775	COG1570	exodeoxyribonuclease VII activity
G9272_RS28780	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G9272_RS28795	COG0012	GTP binding
G9272_RS28865	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G9272_RS28900	COG1131	(ABC) transporter
G9272_RS28910	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G9272_RS28915	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS28920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9272_RS28925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9272_RS28940	COG2423	ornithine cyclodeaminase activity
G9272_RS28950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9272_RS28955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G9272_RS28975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9272_RS28990	COG2814	Major facilitator Superfamily
G9272_RS29010	COG3629	intracellular signal transduction
G9272_RS29010	COG3903	Transcriptional regulator
G9272_RS29060	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G9272_RS29065	COG1053	succinate dehydrogenase
G9272_RS29085	COG1217	gtp-binding protein TYPA
G9272_RS29090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9272_RS29095	COG4166	transmembrane transport
G9272_RS29100	COG0601	transmembrane transport
G9272_RS29105	COG0444	Belongs to the ABC transporter superfamily
G9272_RS29110	COG4608	Belongs to the ABC transporter superfamily
G9272_RS29120	COG2318	DinB family
G9272_RS29130	COG3629	intracellular signal transduction
G9272_RS29130	COG3903	Transcriptional regulator
G9272_RS29155	COG1132	(ABC) transporter
G9272_RS29160	COG0515	serine threonine protein kinase
G9272_RS29165	COG4608	Belongs to the ABC transporter superfamily
G9272_RS29170	COG0444	Belongs to the ABC transporter superfamily
G9272_RS29175	COG0601	transmembrane transport
G9272_RS29180	COG0747	negative chemotaxis
G9272_RS29185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9272_RS29195	COG0601	transmembrane transport
G9272_RS29200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9272_RS29205	COG0444	Belongs to the ABC transporter superfamily
G9272_RS29210	COG4608	Belongs to the ABC transporter superfamily
G9272_RS29250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G9272_RS29265	COG1131	(ABC) transporter
G9272_RS29275	COG4585	Histidine kinase
G9272_RS29280	COG2197	response regulator
G9272_RS29315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G9272_RS29320	COG1611	Belongs to the LOG family
G9272_RS29325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G9272_RS29335	COG0519	Catalyzes the synthesis of GMP from XMP
G9272_RS29340	COG1024	Enoyl-CoA hydratase
G9272_RS29355	COG1595	DNA-templated transcription, initiation
G9272_RS29365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G9272_RS29370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G9272_RS29405	COG0598	Magnesium transport protein CorA
G9272_RS29415	COG2814	Major facilitator Superfamily
G9272_RS29430	COG2095	MarC family integral membrane protein
G9272_RS29440	COG1432	Conserved Protein
G9272_RS29450	COG0513	Belongs to the DEAD box helicase family
G9272_RS29490	COG0747	negative chemotaxis
G9272_RS29495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9272_RS29500	COG0601	transmembrane transport
G9272_RS29535	COG0596	Alpha beta hydrolase
G9272_RS29560	COG0210	DNA helicase
G9272_RS29565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G9272_RS29605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G9272_RS29655	COG3480	Lon protease (S16) C-terminal proteolytic domain
G9272_RS29665	COG1615	UPF0182 protein
G9272_RS29695	COG0483	inositol monophosphate 1-phosphatase activity
G9272_RS29705	COG2076	Multidrug Resistance protein
G9272_RS29715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G9272_RS29725	COG2135	peptidase activity
G9272_RS29735	COG1595	DNA-templated transcription, initiation
G9272_RS29740	COG5662	AntiSigma factor
G9272_RS29760	COG0242	peptide deformylase activity
G9272_RS29770	COG2124	cytochrome p450
G9272_RS29785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G9272_RS29810	COG2188	Transcriptional regulator
G9272_RS29815	COG2182	Extracellular solute-binding protein
G9272_RS29820	COG1175	transmembrane transport
G9272_RS29825	COG0395	ABC-type sugar transport system, permease component
G9272_RS29830	COG1472	Belongs to the glycosyl hydrolase 3 family
G9272_RS29835	COG0363	glucosamine-6-phosphate deaminase activity
G9272_RS29850	COG1597	lipid kinase activity
G9272_RS29880	COG2515	1-aminocyclopropane-1-carboxylate deaminase
G9272_RS29885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G9272_RS29890	COG0142	geranyltranstransferase activity
G9272_RS29940	COG4106	trans-aconitate 2-methyltransferase activity
G9272_RS29945	COG1126	abc transporter atp-binding protein
G9272_RS29950	COG0765	amino acid transport
G9272_RS29960	COG0281	malic enzyme
G9272_RS29965	COG0604	alcohol dehydrogenase
G9272_RS30040	COG0567	Dehydrogenase, E1 component
G9272_RS30040	COG0508	dehydrogenase complex catalyzes the overall conversion of
G9272_RS30045	COG2205	protein histidine kinase activity
G9272_RS30050	COG0745	RESPONSE REGULATOR receiver
G9272_RS30075	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G9272_RS30115	COG0791	NLP P60 protein
G9272_RS30125	COG1309	transcriptional regulator
G9272_RS30155	COG0768	penicillin binding
G9272_RS30170	COG2205	protein histidine kinase activity
G9272_RS30190	COG1793	dna ligase
G9272_RS30190	COG3285	dna ligase
G9272_RS30195	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G9272_RS30205	COG2807	transmembrane transport
G9272_RS30220	COG1609	Transcriptional regulator
G9272_RS30400	COG0018	arginyl-trna synthetase
G9272_RS30405	COG0019	diaminopimelate decarboxylase activity
G9272_RS30410	COG0460	homoserine dehydrogenase
G9272_RS30415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G9272_RS30420	COG0083	homoserine kinase activity
G9272_RS30440	COG0254	rRNA binding
G9272_RS30445	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G9272_RS30450	COG2890	protein-(glutamine-N5) methyltransferase activity
G9272_RS30460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G9272_RS30465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G9272_RS30470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G9272_RS30485	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G9272_RS30490	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G9272_RS30495	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G9272_RS30500	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G9272_RS30505	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G9272_RS30510	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G9272_RS30515	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G9272_RS30530	COG2197	response regulator
G9272_RS30535	COG3850	Histidine kinase
G9272_RS30560	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
G9272_RS30595	COG1131	(ABC) transporter
G9272_RS30610	COG0346	lactoylglutathione lyase activity
G9272_RS30615	COG0183	Belongs to the thiolase family
G9272_RS30635	COG0745	RESPONSE REGULATOR receiver
G9272_RS30700	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G9272_RS30700	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G9272_RS30735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G9272_RS30740	COG0280	phosphate acetyltransferase
G9272_RS30740	COG0857	belongs to the CobB CobQ family
G9272_RS30745	COG0205	6-phosphofructokinase activity
G9272_RS30755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G9272_RS30765	COG4565	transcriptional regulatory protein
G9272_RS30770	COG3290	protein histidine kinase activity
G9272_RS30775	COG1301	dicarboxylic acid transport
G9272_RS30780	COG0667	Aldo Keto reductase
G9272_RS30790	COG1522	sequence-specific DNA binding
G9272_RS30800	COG0492	ferredoxin-NADP+ reductase activity
G9272_RS30800	COG3118	belongs to the thioredoxin family
G9272_RS30810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G9272_RS30825	COG0366	Alpha amylase catalytic
G9272_RS30835	COG0058	SHG alpha-glucan phosphorylase activity
G9272_RS30850	COG0714	Associated with various cellular activities
G9272_RS30875	COG1132	(ABC) transporter
G9272_RS30880	COG1132	(ABC) transporter
G9272_RS30885	COG1132	(ABC) transporter
G9272_RS30890	COG1132	(ABC) transporter
G9272_RS30900	COG3119	arylsulfatase activity
G9272_RS30915	COG1376	ErfK ybiS ycfS ynhG family protein
G9272_RS30950	COG0789	Transcriptional regulator
G9272_RS30965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G9272_RS30975	COG1760	l-serine dehydratase
G9272_RS30980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G9272_RS30985	COG0509	glycine decarboxylation via glycine cleavage system
G9272_RS30990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G9272_RS31010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9272_RS31025	COG0444	Belongs to the ABC transporter superfamily
G9272_RS31030	COG4608	Belongs to the ABC transporter superfamily
G9272_RS31035	COG2860	membrane
G9272_RS31040	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G9272_RS31075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G9272_RS31085	COG2132	Multicopper oxidase
G9272_RS31090	COG3023	N-Acetylmuramoyl-L-alanine amidase
G9272_RS31095	COG0482	sulfurtransferase activity
G9272_RS31110	COG1611	Belongs to the LOG family
G9272_RS31125	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G9272_RS31135	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G9272_RS31140	COG0154	amidase activity
G9272_RS31150	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G9272_RS31160	COG2409	Drug exporters of the RND superfamily
G9272_RS31165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9272_RS31180	COG1672	PFAM Archaeal ATPase
G9272_RS31180	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G9272_RS31190	COG2133	pyrroloquinoline quinone binding
G9272_RS31195	COG0667	Aldo Keto reductase
G9272_RS31205	COG3300	MHYT domain
G9272_RS31205	COG5001	Diguanylate cyclase
G9272_RS31215	COG0440	acetolactate synthase activity
G9272_RS31220	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G9272_RS31225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G9272_RS31230	COG0477	Major facilitator Superfamily
G9272_RS31240	COG2508	Transcriptional regulator
G9272_RS31245	COG0506	proline dehydrogenase activity
G9272_RS31250	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS31260	COG2130	NADP-dependent
G9272_RS31270	COG0473	3-isopropylmalate dehydrogenase activity
G9272_RS31275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G9272_RS31280	COG0831	urea catabolic process
G9272_RS31280	COG0832	Belongs to the urease beta subunit family
G9272_RS31285	COG0804	urea catabolic process
G9272_RS31290	COG2957	Belongs to the agmatine deiminase family
G9272_RS31300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G9272_RS31355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G9272_RS31375	COG2018	Roadblock/LC7 domain
G9272_RS31395	COG2018	Roadblock/LC7 domain
G9272_RS31400	COG5002	protein histidine kinase activity
G9272_RS31410	COG0179	Fumarylacetoacetate (FAA) hydrolase
G9272_RS31415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G9272_RS31460	COG1414	Transcriptional regulator
G9272_RS31465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G9272_RS31470	COG0066	3-isopropylmalate dehydratase activity
G9272_RS31480	COG0776	regulation of translation
G9272_RS31490	COG1920	GTP binding
G9272_RS31500	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G9272_RS31505	COG1181	Belongs to the D-alanine--D-alanine ligase family
G9272_RS31525	COG0351	phosphomethylpyrimidine kinase
G9272_RS31540	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G9272_RS31545	COG1461	Dihydroxyacetone kinase
G9272_RS31555	COG0326	Molecular chaperone. Has ATPase activity
G9272_RS31565	COG0742	ribosomal rna small subunit methyltransferase
G9272_RS31570	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G9272_RS31585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G9272_RS31590	COG0571	ribonuclease III activity
G9272_RS31595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G9272_RS31600	COG1733	regulation of RNA biosynthetic process
G9272_RS31605	COG0655	NAD(P)H dehydrogenase (quinone) activity
G9272_RS31610	COG2340	Cysteine-rich secretory protein family
G9272_RS31615	COG1254	Belongs to the acylphosphatase family
G9272_RS31630	COG0477	Major facilitator Superfamily
G9272_RS31665	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G9272_RS31680	COG0442	prolyl-tRNA aminoacylation
G9272_RS31690	COG0228	four-way junction DNA binding
G9272_RS31695	COG1837	Belongs to the UPF0109 family
G9272_RS31700	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G9272_RS31705	COG0336	Belongs to the RNA methyltransferase TrmD family
G9272_RS31710	COG0335	large ribosomal subunit rRNA binding
G9272_RS31715	COG0681	Belongs to the peptidase S26 family
G9272_RS31720	COG0681	Belongs to the peptidase S26 family
G9272_RS31735	COG0494	nUDIX hydrolase
G9272_RS31745	COG0792	nuclease activity
G9272_RS31755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G9272_RS31775	COG2188	Transcriptional regulator
G9272_RS32190	COG1191	sigma factor activity
G9272_RS32205	COG0052	Belongs to the universal ribosomal protein uS2 family
G9272_RS32210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G9272_RS32215	COG0528	UMP kinase activity
G9272_RS32220	COG0233	cytoplasmic translational termination
G9272_RS32225	COG0575	Belongs to the CDS family
G9272_RS32235	COG1846	Transcriptional regulator
G9272_RS32240	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G9272_RS32250	COG4208	sulfate ABC transporter
G9272_RS32255	COG3842	ATPase activity
G9272_RS32285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G9272_RS32295	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS32310	COG0300	oxidoreductase activity
G9272_RS32330	COG1595	DNA-templated transcription, initiation
G9272_RS32370	COG1733	regulation of RNA biosynthetic process
G9272_RS32385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G9272_RS32410	COG3842	ATPase activity
G9272_RS32415	COG1176	ABC-type spermidine putrescine transport system, permease component I
G9272_RS32420	COG1177	transmembrane transport
G9272_RS32425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9272_RS32435	COG2508	Transcriptional regulator
G9272_RS32455	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS32470	COG4209	transmembrane transport
G9272_RS32475	COG0395	ABC-type sugar transport system, permease component
G9272_RS32545	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G9272_RS32550	COG0750	zinc metalloprotease
G9272_RS32555	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G9272_RS32570	COG0442	prolyl-tRNA aminoacylation
G9272_RS32620	COG0779	Required for maturation of 30S ribosomal subunits
G9272_RS32635	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G9272_RS32645	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G9272_RS32650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G9272_RS32665	COG0455	bacterial-type flagellum organization
G9272_RS32685	COG1404	Belongs to the peptidase S8 family
G9272_RS32725	COG1404	Belongs to the peptidase S8 family
G9272_RS32760	COG1674	ftsk spoiiie
G9272_RS32775	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G9272_RS32780	COG1185	polyribonucleotide nucleotidyltransferase activity
G9272_RS32785	COG0612	Peptidase, M16
G9272_RS32790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G9272_RS32810	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
G9272_RS32815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G9272_RS32820	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G9272_RS32850	COG2208	phosphoserine phosphatase activity
G9272_RS32850	COG2770	Histidine kinase
G9272_RS32855	COG2205	protein histidine kinase activity
G9272_RS32855	COG3437	response regulator, receiver
G9272_RS32855	COG3850	Histidine kinase
G9272_RS32855	COG4999	Histidine kinase
G9272_RS32865	COG1674	ftsk spoiiie
G9272_RS32875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G9272_RS32885	COG1546	Belongs to the CinA family
G9272_RS32885	COG1058	Belongs to the CinA family
G9272_RS32890	COG1396	sequence-specific DNA binding
G9272_RS32895	COG0783	Belongs to the Dps family
G9272_RS32900	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS32905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G9272_RS32910	COG1201	RNA secondary structure unwinding
G9272_RS32915	COG1917	Cupin 2, conserved barrel domain protein
G9272_RS32915	COG2207	Transcriptional regulator
G9272_RS32940	COG0628	permease
G9272_RS32950	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G9272_RS32970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G9272_RS32980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9272_RS32990	COG0765	amino acid transport
G9272_RS32995	COG0765	amino acid transport
G9272_RS33000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9272_RS33005	COG1126	abc transporter atp-binding protein
G9272_RS33010	COG0745	RESPONSE REGULATOR receiver
G9272_RS33050	COG2197	response regulator
G9272_RS33055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G9272_RS33075	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G9272_RS33085	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G9272_RS33090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G9272_RS33100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G9272_RS33135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G9272_RS33140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G9272_RS33145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G9272_RS33160	COG0588	phosphoglycerate mutase activity
G9272_RS33180	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G9272_RS33220	COG2186	Transcriptional regulator
G9272_RS33225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G9272_RS33240	COG0187	DNA topoisomerase II activity
G9272_RS33255	COG2197	response regulator
G9272_RS33265	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9272_RS33270	COG4565	transcriptional regulatory protein
G9272_RS33280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G9272_RS33290	COG4565	transcriptional regulatory protein
G9272_RS33295	COG3290	protein histidine kinase activity
G9272_RS33325	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G9272_RS33330	COG0612	Peptidase, M16
G9272_RS33345	COG1802	Transcriptional regulator
G9272_RS33350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9272_RS33355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9272_RS33355	COG1042	CoA-binding domain protein
G9272_RS33355	COG0045	succinate-CoA ligase (ADP-forming) activity
G9272_RS33370	COG1435	thymidine kinase activity
G9272_RS33405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G9272_RS33420	COG0745	RESPONSE REGULATOR receiver
G9272_RS33425	COG2205	protein histidine kinase activity
G9272_RS33450	COG0756	dUTP diphosphatase activity
G9272_RS33490	COG0569	domain protein
G9272_RS33495	COG0531	amino acid
G9272_RS33500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G9272_RS33590	COG0515	serine threonine protein kinase
G9272_RS33590	COG2815	serine threonine protein kinase
G9272_RS33675	COG2814	Major facilitator Superfamily
G9272_RS33695	COG0477	Major facilitator Superfamily
G9272_RS33705	COG2353	YceI-like domain
G9272_RS33710	COG1799	cell septum assembly
G9272_RS33750	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G9272_RS33770	COG2235	arginine
G9272_RS33775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G9272_RS33785	COG1024	Enoyl-CoA hydratase
G9272_RS33835	COG0725	ABC transporter, periplasmic molybdate-binding protein
G9272_RS33865	COG2319	Wd-40 repeat
G9272_RS33865	COG4249	Peptidase C14 caspase catalytic subunit p20
G9272_RS33935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G9272_RS33945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G9272_RS33960	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G9272_RS33965	COG0745	RESPONSE REGULATOR receiver
G9272_RS33970	COG2205	protein histidine kinase activity
G9272_RS33985	COG3458	cephalosporin-C deacetylase activity
G9272_RS33990	COG4209	transmembrane transport
G9272_RS33995	COG0395	ABC-type sugar transport system, permease component
G9272_RS34000	COG1653	transport
G9272_RS34035	COG1653	transport
G9272_RS34040	COG1175	transmembrane transport
G9272_RS34045	COG0395	ABC-type sugar transport system, permease component
G9272_RS34050	COG1940	carbohydrate kinase activity
G9272_RS34055	COG4213	ABC transporter substrate-binding protein
G9272_RS34065	COG4214	carbohydrate transport
G9272_RS34070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G9272_RS34075	COG0531	amino acid
G9272_RS34090	COG1024	Enoyl-CoA hydratase
G9272_RS34090	COG1250	3-hydroxyacyl-CoA dehydrogenase
G9272_RS34095	COG0183	Belongs to the thiolase family
G9272_RS34100	COG1609	Transcriptional regulator
G9272_RS34105	COG3250	beta-galactosidase activity
G9272_RS34115	COG1175	transmembrane transport
G9272_RS34120	COG3833	ABC-type maltose transport systems, permease component
G9272_RS34125	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G9272_RS34140	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G9272_RS34155	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9272_RS34170	COG3253	May function as heme-dependent peroxidase
G9272_RS34190	COG3220	belongs to the UPF0276 family
G9272_RS34200	COG3842	ATPase activity
G9272_RS34225	COG0330	HflC and HflK could
G9272_RS34260	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G9272_RS34265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G9272_RS34275	COG2205	protein histidine kinase activity
G9272_RS34280	COG0745	RESPONSE REGULATOR receiver
G9272_RS34285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9272_RS34295	COG1477	protein flavinylation
G9272_RS34300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G9272_RS34320	COG1174	glycine betaine transport
G9272_RS34325	COG1174	glycine betaine transport
G9272_RS34345	COG2018	Roadblock/LC7 domain
G9272_RS34350	COG5002	protein histidine kinase activity
G9272_RS34360	COG2986	histidine ammonia-lyase
G9272_RS34390	COG0642	Histidine kinase
G9272_RS34430	COG1404	Belongs to the peptidase S8 family
G9272_RS34435	COG1309	transcriptional regulator
G9272_RS34450	COG0504	CTP synthase activity
G9272_RS34465	COG1280	lysine exporter protein (LysE YggA)
G9272_RS34565	COG0745	RESPONSE REGULATOR receiver
G9272_RS34570	COG2205	protein histidine kinase activity
G9272_RS34600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G9272_RS34615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G9272_RS34620	COG1116	anion transmembrane transporter activity
G9272_RS34645	COG0529	Catalyzes the synthesis of activated sulfate
G9272_RS34650	COG0175	sulfate reduction
G9272_RS34665	COG0456	acetyltransferase
G9272_RS34680	COG1960	acyl-CoA dehydrogenase activity
G9272_RS34695	COG1917	Cupin 2, conserved barrel domain protein
G9272_RS34695	COG4977	sequence-specific DNA binding
G9272_RS34720	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G9272_RS34735	COG1609	Transcriptional regulator
G9272_RS34740	COG3507	Belongs to the glycosyl hydrolase 43 family
G9272_RS34750	COG1175	transmembrane transport
G9272_RS34765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G9272_RS34775	COG1175	transmembrane transport
G9272_RS34780	COG0395	ABC-type sugar transport system, permease component
G9272_RS34805	COG1609	Transcriptional regulator
G9272_RS34810	COG2040	homocysteine
G9272_RS34835	COG2755	lipolytic protein G-D-S-L family
G9272_RS34890	COG1131	(ABC) transporter
G9272_RS34900	COG0395	ABC-type sugar transport system, permease component
G9272_RS34920	COG0277	FAD linked oxidase domain protein
G9272_RS34935	COG1162	GTPase activity
G9272_RS34945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G9272_RS34965	COG0028	Belongs to the TPP enzyme family
G9272_RS35010	COG1802	Transcriptional regulator
G9272_RS35035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G9272_RS35040	COG2252	PERMEase
G9272_RS35060	COG0726	polysaccharide deacetylase
G9272_RS35065	COG3940	Belongs to the glycosyl hydrolase 43 family
G9272_RS35070	COG3940	Belongs to the glycosyl hydrolase 43 family
G9272_RS35075	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G9272_RS35090	COG2197	response regulator
G9272_RS35095	COG4585	Histidine kinase
G9272_RS35100	COG2409	Drug exporters of the RND superfamily
G9272_RS35120	COG0179	Fumarylacetoacetate (FAA) hydrolase
G9272_RS35125	COG3485	protocatechuate 3,4-dioxygenase
G9272_RS35130	COG3250	beta-galactosidase activity
G9272_RS35135	COG0657	acetylesterase activity
G9272_RS35145	COG1414	Transcriptional regulator
G9272_RS35150	COG0477	Major facilitator Superfamily
G9272_RS35170	COG2197	response regulator
G9272_RS35175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G9272_RS35180	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS35190	COG3960	tartronate-semialdehyde synthase activity
G9272_RS35205	COG2084	Dehydrogenase
G9272_RS35210	COG3622	Belongs to the hyi family
G9272_RS35230	COG2351	hydroxyisourate hydrolase activity
G9272_RS35260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G9272_RS35270	COG1733	regulation of RNA biosynthetic process
G9272_RS35285	COG0406	alpha-ribazole phosphatase activity
G9272_RS35290	COG0436	Aminotransferase
G9272_RS35320	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G9272_RS35330	COG3486	L-lysine 6-monooxygenase (NADPH) activity
G9272_RS35340	COG1120	ATPase activity
G9272_RS35345	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9272_RS35350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9272_RS35360	COG3251	PFAM MbtH domain protein
G9272_RS35365	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G9272_RS35370	COG1132	(ABC) transporter
G9272_RS35375	COG1132	(ABC) transporter
G9272_RS35385	COG1120	ATPase activity
G9272_RS35390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9272_RS35410	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G9272_RS35425	COG1414	Transcriptional regulator
G9272_RS35430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G9272_RS35435	COG4266	Belongs to the allantoicase family
G9272_RS35440	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS35470	COG2197	response regulator
G9272_RS35480	COG0673	inositol 2-dehydrogenase activity
G9272_RS35485	COG2188	Transcriptional regulator
G9272_RS35495	COG1940	carbohydrate kinase activity
G9272_RS35505	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G9272_RS35525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9272_RS35530	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G9272_RS35535	COG0708	Exodeoxyribonuclease III
G9272_RS35545	COG1126	abc transporter atp-binding protein
G9272_RS35550	COG2936	dipeptidyl-peptidase activity
G9272_RS35560	COG0405	Gamma-glutamyltransferase
G9272_RS35565	COG0542	response to heat
G9272_RS35605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G9272_RS35615	COG1953	Uracil, thiamine, allantoin
G9272_RS35630	COG0483	inositol monophosphate 1-phosphatase activity
G9272_RS35640	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
G9272_RS35680	COG0243	molybdopterin cofactor binding
G9272_RS35720	COG3511	phospholipase C
G9272_RS35735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G9272_RS35745	COG0494	nUDIX hydrolase
G9272_RS35755	COG1929	Belongs to the glycerate kinase type-1 family
G9272_RS35765	COG0688	phosphatidylethanolamine metabolic process
G9272_RS35770	COG1960	acyl-CoA dehydrogenase activity
G9272_RS35780	COG2301	Belongs to the HpcH HpaI aldolase family
G9272_RS35785	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G9272_RS35785	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G9272_RS35790	COG0604	alcohol dehydrogenase
G9272_RS35800	COG1250	3-hydroxyacyl-CoA dehydrogenase
G9272_RS35820	COG0596	Alpha beta hydrolase
G9272_RS35875	COG2072	flavoprotein involved in K transport
G9272_RS35880	COG2362	D-Aminopeptidase
G9272_RS35885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G9272_RS35890	COG0823	Involved in the tonB-independent uptake of proteins
G9272_RS35890	COG4946	Tricorn protease homolog
G9272_RS35890	COG1506	peptidase
G9272_RS35895	COG1619	proteins homologs of microcin C7 resistance protein MccF
G9272_RS35905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9272_RS35935	COG1793	dna ligase
G9272_RS35935	COG3285	dna ligase
G9272_RS35995	COG2226	methyltransferase
G9272_RS36005	COG0406	alpha-ribazole phosphatase activity
G9272_RS36010	COG0488	(ABC) transporter
G9272_RS36030	COG0028	Belongs to the TPP enzyme family
G9272_RS36120	COG2154	pterin-4-alpha-carbinolamine dehydratase
G9272_RS36125	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G9272_RS36125	COG4106	trans-aconitate 2-methyltransferase activity
G9272_RS36140	COG2378	regulation of single-species biofilm formation
G9272_RS36145	COG3401	FG-GAP repeat protein
G9272_RS36155	COG5297	Belongs to the glycosyl hydrolase family 6
G9272_RS36155	COG4733	cellulase activity
G9272_RS36160	COG5297	Belongs to the glycosyl hydrolase family 6
G9272_RS36165	COG5297	Belongs to the glycosyl hydrolase family 6
G9272_RS36175	COG4221	oxidoreductase activity
G9272_RS36180	COG0656	L-ascorbic acid biosynthetic process
G9272_RS36210	COG1063	alcohol dehydrogenase
G9272_RS36215	COG1846	Transcriptional regulator
G9272_RS36220	COG1335	isochorismatase
G9272_RS36225	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G9272_RS36240	COG3383	formate dehydrogenase (NAD+) activity
G9272_RS36245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G9272_RS36260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G9272_RS36270	COG1940	carbohydrate kinase activity
G9272_RS36275	COG1129	ABC transporter
G9272_RS36280	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9272_RS36290	COG0673	inositol 2-dehydrogenase activity
G9272_RS36350	COG2223	nitrite transmembrane transporter activity
G9272_RS36360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G9272_RS36370	COG0045	succinate-CoA ligase (ADP-forming) activity
G9272_RS36380	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS36425	COG2072	flavoprotein involved in K transport
G9272_RS36435	COG3938	Belongs to the proline racemase family
G9272_RS36440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G9272_RS36445	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9272_RS36455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9272_RS36470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G9272_RS36480	COG2182	Extracellular solute-binding protein
G9272_RS36485	COG1175	transmembrane transport
G9272_RS36490	COG0395	ABC-type sugar transport system, permease component
G9272_RS36495	COG2723	6-phospho-beta-galactosidase activity
G9272_RS36500	COG2273	Hydrolase Family 16
G9272_RS36530	COG0747	negative chemotaxis
G9272_RS36535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9272_RS36570	COG0297	glycogen (starch) synthase activity
G9272_RS36590	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G9272_RS36595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9272_RS36615	COG0477	Major facilitator Superfamily
G9272_RS36625	COG3467	pyridoxamine 5'-phosphate
G9272_RS36650	COG0477	Major facilitator Superfamily
G9272_RS36660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G9272_RS36665	COG3185	4-Hydroxyphenylpyruvate dioxygenase
G9272_RS36665	COG1082	Xylose isomerase domain protein TIM barrel
G9272_RS36675	COG0588	phosphoglycerate mutase activity
G9272_RS36680	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G9272_RS36685	COG0166	Belongs to the GPI family
G9272_RS36700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G9272_RS36705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G9272_RS36760	COG1131	(ABC) transporter
G9272_RS36785	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS36810	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G9272_RS36815	COG3250	beta-galactosidase activity
G9272_RS36820	COG0395	ABC-type sugar transport system, permease component
G9272_RS36825	COG1175	transmembrane transport
G9272_RS36835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9272_RS36845	COG1486	melibiose metabolic process
G9272_RS36860	COG3469	chitinase activity
G9272_RS36870	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G9272_RS36905	COG1116	anion transmembrane transporter activity
G9272_RS36910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G9272_RS36915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G9272_RS36975	COG0667	Aldo Keto reductase
G9272_RS36990	COG2814	Major facilitator Superfamily
G9272_RS37000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G9272_RS37005	COG1309	transcriptional regulator
G9272_RS37015	COG1024	Enoyl-CoA hydratase
G9272_RS37030	COG0535	radical SAM domain protein
G9272_RS37070	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS37085	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS37100	COG1024	Enoyl-CoA hydratase
G9272_RS37130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G9272_RS37145	COG1960	acyl-CoA dehydrogenase activity
G9272_RS37160	COG1024	Enoyl-CoA hydratase
G9272_RS37165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G9272_RS37170	COG0183	Belongs to the thiolase family
G9272_RS37180	COG1960	acyl-CoA dehydrogenase activity
G9272_RS37185	COG2188	Transcriptional regulator
G9272_RS37200	COG1960	acyl-CoA dehydrogenase activity
G9272_RS37205	COG3321	synthase
G9272_RS37205	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS37205	COG0604	alcohol dehydrogenase
G9272_RS37210	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS37225	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS37235	COG0346	lactoylglutathione lyase activity
G9272_RS37250	COG1053	succinate dehydrogenase
G9272_RS37255	COG3971	2-oxopent-4-enoate hydratase activity
G9272_RS37265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G9272_RS37290	COG1063	alcohol dehydrogenase
G9272_RS37295	COG1960	acyl-CoA dehydrogenase activity
G9272_RS37300	COG1309	transcriptional regulator
G9272_RS37305	COG0022	dehydrogenase e1 component
G9272_RS37325	COG2072	flavoprotein involved in K transport
G9272_RS37330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9272_RS37355	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS37385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G9272_RS37390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G9272_RS37400	COG0438	transferase activity, transferring glycosyl groups
G9272_RS37415	COG3511	phospholipase C
G9272_RS37450	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9272_RS37455	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G9272_RS37460	COG3485	protocatechuate 3,4-dioxygenase
G9272_RS37465	COG3485	protocatechuate 3,4-dioxygenase
G9272_RS37470	COG0183	Belongs to the thiolase family
G9272_RS37485	COG1846	Transcriptional regulator
G9272_RS37500	COG1793	dna ligase
G9272_RS37585	COG1834	amidinotransferase
G9272_RS37590	COG0488	(ABC) transporter
G9272_RS37610	COG1515	deoxyribonuclease V activity
G9272_RS37620	COG3268	Saccharopine dehydrogenase
G9272_RS37625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G9272_RS37630	COG0183	Belongs to the thiolase family
G9272_RS37635	COG1250	3-hydroxyacyl-CoA dehydrogenase
G9272_RS37635	COG1024	Enoyl-CoA hydratase
G9272_RS37645	COG1113	amino acid transport
G9272_RS37655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9272_RS37670	COG2936	dipeptidyl-peptidase activity
G9272_RS37675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9272_RS37680	COG0488	(ABC) transporter
G9272_RS37685	COG2183	response to ionizing radiation
G9272_RS37690	COG4977	sequence-specific DNA binding
G9272_RS37710	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
G9272_RS37750	COG1134	teichoic acid transport
G9272_RS37755	COG1562	ergosterol biosynthetic process
G9272_RS37765	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
G9272_RS37775	COG1657	PFAM Prenyltransferase squalene oxidase
G9272_RS37790	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G9272_RS37795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G9272_RS37815	COG2365	Tyrosine phosphatase family
G9272_RS37840	COG3401	FG-GAP repeat protein
G9272_RS37850	COG2755	lipolytic protein G-D-S-L family
G9272_RS37905	COG1063	alcohol dehydrogenase
G9272_RS37910	COG0156	8-amino-7-oxononanoate synthase activity
G9272_RS37915	COG0583	DNA-binding transcription factor activity
G9272_RS37965	COG0174	glutamine synthetase
G9272_RS37975	COG0561	phosphatase activity
G9272_RS38000	COG2267	carboxylic ester hydrolase activity
G9272_RS38005	COG0183	Belongs to the thiolase family
G9272_RS38045	COG1960	acyl-CoA dehydrogenase activity
G9272_RS38055	COG2188	Transcriptional regulator
G9272_RS38085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G9272_RS38095	COG0673	inositol 2-dehydrogenase activity
G9272_RS38100	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS38120	COG0673	inositol 2-dehydrogenase activity
G9272_RS38140	COG2186	Transcriptional regulator
G9272_RS38145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G9272_RS38150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G9272_RS38155	COG2828	Protein conserved in bacteria
G9272_RS38165	COG2814	Major facilitator Superfamily
G9272_RS38185	COG1129	ABC transporter
G9272_RS38190	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9272_RS38195	COG1879	ABC-type sugar transport system periplasmic component
G9272_RS38200	COG0583	DNA-binding transcription factor activity
G9272_RS38205	COG0346	lactoylglutathione lyase activity
G9272_RS38225	COG2267	carboxylic ester hydrolase activity
G9272_RS38245	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS38250	COG0579	oxidoreductase
G9272_RS38260	COG3962	Belongs to the TPP enzyme family
G9272_RS38280	COG1819	glycosyl
G9272_RS38305	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS38335	COG3425	synthase
G9272_RS38345	COG3321	synthase
G9272_RS38345	COG0604	alcohol dehydrogenase
G9272_RS38365	COG0604	alcohol dehydrogenase
G9272_RS38370	COG2124	cytochrome p450
G9272_RS38390	COG0546	phosphoglycolate phosphatase activity
G9272_RS38420	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G9272_RS38425	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G9272_RS38430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS38435	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS38455	COG3251	PFAM MbtH domain protein
G9272_RS38460	COG4122	O-methyltransferase activity
G9272_RS38465	COG2124	cytochrome p450
G9272_RS38470	COG3321	synthase
G9272_RS38470	COG0604	alcohol dehydrogenase
G9272_RS38485	COG2890	protein-(glutamine-N5) methyltransferase activity
G9272_RS38490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G9272_RS38495	COG1960	acyl-CoA dehydrogenase activity
G9272_RS38515	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS38530	COG3265	gluconokinase activity
G9272_RS38575	COG3629	intracellular signal transduction
G9272_RS38575	COG3903	Transcriptional regulator
G9272_RS38665	COG1126	abc transporter atp-binding protein
G9272_RS38675	COG0456	acetyltransferase
G9272_RS38680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS38685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS38690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS38695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS38700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G9272_RS38705	COG1116	anion transmembrane transporter activity
G9272_RS38710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G9272_RS38720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G9272_RS38730	COG0477	Major facilitator Superfamily
G9272_RS38780	COG2838	Isocitrate dehydrogenase
G9272_RS38790	COG0668	transmembrane transport
G9272_RS38805	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G9272_RS38825	COG1132	(ABC) transporter
G9272_RS38835	COG2409	Drug exporters of the RND superfamily
G9272_RS38840	COG4585	Histidine kinase
G9272_RS38845	COG2197	response regulator
G9272_RS38850	COG1295	ribonuclease BN
G9272_RS38885	COG4977	sequence-specific DNA binding
G9272_RS38895	COG3224	Antibiotic biosynthesis monooxygenase
G9272_RS38900	COG0604	alcohol dehydrogenase
G9272_RS38900	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS38900	COG3321	synthase
G9272_RS38905	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G9272_RS38915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G9272_RS38935	COG0297	glycogen (starch) synthase activity
G9272_RS38940	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G9272_RS38955	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS38970	COG0154	amidase activity
G9272_RS38975	COG2186	Transcriptional regulator
G9272_RS38980	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS39015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G9272_RS39045	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G9272_RS39045	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G9272_RS39050	COG0726	polysaccharide deacetylase
G9272_RS39100	COG0583	DNA-binding transcription factor activity
G9272_RS39110	COG0583	DNA-binding transcription factor activity
G9272_RS39120	COG1053	succinate dehydrogenase
G9272_RS39125	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G9272_RS39150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS39160	COG3360	Dodecin
G9272_RS39165	COG2182	Extracellular solute-binding protein
G9272_RS39170	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G9272_RS39175	COG0121	glutamine amidotransferase
G9272_RS39180	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G9272_RS39200	COG2268	Band 7 protein
G9272_RS39245	COG1045	serine acetyltransferase
G9272_RS39270	COG2205	protein histidine kinase activity
G9272_RS39275	COG0745	RESPONSE REGULATOR receiver
G9272_RS39295	COG0477	Major facilitator Superfamily
G9272_RS39300	COG2197	response regulator
G9272_RS39365	COG1609	Transcriptional regulator
G9272_RS39380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G9272_RS39390	COG0242	peptide deformylase activity
G9272_RS39415	COG2124	cytochrome p450
G9272_RS39430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G9272_RS39460	COG2197	response regulator
G9272_RS39465	COG4585	Histidine kinase
G9272_RS39495	COG0202	RNA polymerase activity
G9272_RS39505	COG0583	DNA-binding transcription factor activity
G9272_RS39620	COG0542	response to heat
G9272_RS39630	COG0702	epimerase
G9272_RS39635	COG1733	regulation of RNA biosynthetic process
G9272_RS39640	COG1556	Lactate utilization protein
G9272_RS39645	COG1139	Iron-sulfur cluster binding protein
G9272_RS39650	COG0247	lactate metabolic process
G9272_RS39655	COG1070	Carbohydrate kinase
G9272_RS39660	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS39660	COG3347	Dehydrogenase
G9272_RS39670	COG1129	ABC transporter
G9272_RS39675	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9272_RS39685	COG1879	ABC-type sugar transport system periplasmic component
G9272_RS39700	COG1609	Transcriptional regulator
G9272_RS39715	COG1357	PFAM Pentapeptide repeats (8 copies)
G9272_RS39725	COG1309	transcriptional regulator
G9272_RS39735	COG2706	6-phosphogluconolactonase activity
G9272_RS39795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G9272_RS39795	COG1796	DNA polymerase
G9272_RS39815	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G9272_RS39825	COG1846	Transcriptional regulator
G9272_RS39830	COG1012	belongs to the aldehyde dehydrogenase family
G9272_RS39880	COG0435	Glutathione S-transferase
G9272_RS39935	COG0667	Aldo Keto reductase
G9272_RS39965	COG3250	beta-galactosidase activity
G9272_RS40020	COG2890	protein-(glutamine-N5) methyltransferase activity
G9272_RS40030	COG0248	Ppx GppA phosphatase
G9272_RS40040	COG2274	protein secretion by the type I secretion system
G9272_RS40070	COG2197	response regulator
G9272_RS40080	COG1132	(ABC) transporter
G9272_RS40090	COG0515	serine threonine protein kinase
G9272_RS40145	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G9272_RS40175	COG3345	alpha-galactosidase
G9272_RS40195	COG1132	(ABC) transporter
G9272_RS40210	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS40240	COG2182	Extracellular solute-binding protein
G9272_RS40245	COG0395	ABC-type sugar transport system, permease component
G9272_RS40250	COG1175	transmembrane transport
G9272_RS40280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G9272_RS40285	COG1653	transport
G9272_RS40290	COG1175	transmembrane transport
G9272_RS40295	COG0395	ABC-type sugar transport system, permease component
G9272_RS40300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G9272_RS40305	COG4948	Mandelate Racemase Muconate Lactonizing
G9272_RS40325	COG1309	transcriptional regulator
G9272_RS40330	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G9272_RS40375	COG1940	carbohydrate kinase activity
G9272_RS40385	COG1175	transmembrane transport
G9272_RS40390	COG0395	ABC-type sugar transport system, permease component
G9272_RS40405	COG0572	uridine kinase
G9272_RS40425	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G9272_RS40445	COG1473	amidohydrolase
G9272_RS40475	COG2409	Drug exporters of the RND superfamily
G9272_RS40500	COG0019	diaminopimelate decarboxylase activity
G9272_RS40520	COG2508	Transcriptional regulator
G9272_RS40540	COG0410	ABC transporter
G9272_RS40545	COG0411	ABC transporter
G9272_RS40550	COG0559	Belongs to the binding-protein-dependent transport system permease family
G9272_RS40565	COG0667	Aldo Keto reductase
G9272_RS40570	COG1132	(ABC) transporter
G9272_RS40595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G9272_RS40600	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G9272_RS40605	COG2080	2 iron, 2 sulfur cluster binding
G9272_RS40620	COG1024	Enoyl-CoA hydratase
G9272_RS40635	COG2814	Major facilitator Superfamily
G9272_RS40640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9272_RS40655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G9272_RS40670	COG0515	serine threonine protein kinase
G9272_RS40670	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9272_RS40685	COG0508	dehydrogenase complex catalyzes the overall conversion of
G9272_RS40685	COG0596	Alpha beta hydrolase
G9272_RS40695	COG2326	polyphosphate kinase activity
G9272_RS40715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9272_RS40715	COG1017	nitric oxide dioxygenase activity
G9272_RS40720	COG0745	RESPONSE REGULATOR receiver
G9272_RS40725	COG2205	protein histidine kinase activity
G9272_RS40735	COG3903	Transcriptional regulator
G9272_RS40735	COG3629	intracellular signal transduction
G9272_RS40765	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS40770	COG2409	Drug exporters of the RND superfamily
G9272_RS40785	COG1132	(ABC) transporter
G9272_RS40855	COG0443	Heat shock 70 kDa protein
G9272_RS40890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G9272_RS40910	COG3290	protein histidine kinase activity
G9272_RS40925	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G9272_RS40930	COG1335	isochorismatase
G9272_RS40960	COG1597	lipid kinase activity
G9272_RS40970	COG2264	protein methyltransferase activity
G9272_RS41005	COG1063	alcohol dehydrogenase
G9272_RS41010	COG0395	ABC-type sugar transport system, permease component
G9272_RS41030	COG0667	Aldo Keto reductase
G9272_RS41040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9272_RS41045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G9272_RS41060	COG3629	intracellular signal transduction
G9272_RS41060	COG3903	Transcriptional regulator
G9272_RS41070	COG3552	Protein containing von Willebrand factor type A (VWA) domain
G9272_RS41075	COG0714	Associated with various cellular activities
G9272_RS41090	COG3507	Belongs to the glycosyl hydrolase 43 family
G9272_RS41100	COG0745	RESPONSE REGULATOR receiver
G9272_RS41120	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G9272_RS41130	COG0739	heme binding
G9272_RS41130	COG0741	lytic transglycosylase activity
G9272_RS41130	COG1196	nuclear chromosome segregation
G9272_RS41135	COG3591	Belongs to the peptidase S1B family
G9272_RS41135	COG1864	DNA RNA non-specific endonuclease
G9272_RS41210	COG0395	ABC-type sugar transport system, permease component
G9272_RS41215	COG4209	transmembrane transport
G9272_RS41220	COG1609	Transcriptional regulator
G9272_RS41285	COG2326	polyphosphate kinase activity
G9272_RS41310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G9272_RS41310	COG1024	Enoyl-CoA hydratase
G9272_RS41320	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
G9272_RS41350	COG0375	protein maturation
G9272_RS41355	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G9272_RS41360	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
G9272_RS41365	COG0298	carbon dioxide binding
G9272_RS41375	COG0309	Hydrogenase expression formation protein (HypE)
G9272_RS41385	COG1609	Transcriptional regulator
G9272_RS41400	COG0395	ABC-type sugar transport system, permease component
G9272_RS41430	COG1120	ATPase activity
G9272_RS41455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G9272_RS41460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9272_RS41465	COG0179	Fumarylacetoacetate (FAA) hydrolase
G9272_RS41515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9272_RS41535	COG1535	isochorismatase
G9272_RS41535	COG3433	isochorismatase activity
G9272_RS41540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9272_RS41550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9272_RS41555	COG1120	ATPase activity
G9272_RS41615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9272_RS41625	COG4172	Belongs to the ABC transporter superfamily
G9272_RS41630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9272_RS41650	COG2815	serine threonine protein kinase
G9272_RS41650	COG0515	serine threonine protein kinase
G9272_RS41695	COG3469	chitinase activity
G9272_RS41710	COG0583	DNA-binding transcription factor activity
G9272_RS41715	COG4213	ABC transporter substrate-binding protein
G9272_RS41720	COG4214	carbohydrate transport
G9272_RS41730	COG1940	carbohydrate kinase activity
G9272_RS41745	COG3940	Belongs to the glycosyl hydrolase 43 family
G9272_RS41765	COG1175	transmembrane transport
G9272_RS41770	COG0395	ABC-type sugar transport system, permease component
G9272_RS41795	COG1252	NADH dehydrogenase
G9272_RS41815	COG3387	PFAM Glycoside hydrolase 15-related
G9272_RS41850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G9272_RS41855	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS41895	COG1940	carbohydrate kinase activity
G9272_RS41895	COG1846	Transcriptional regulator
G9272_RS41900	COG3345	alpha-galactosidase
G9272_RS41925	COG2326	polyphosphate kinase activity
G9272_RS41975	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS42035	COG0697	spore germination
G9272_RS42045	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS42050	COG4948	Mandelate Racemase Muconate Lactonizing
G9272_RS42055	COG0179	Fumarylacetoacetate (FAA) hydrolase
G9272_RS42065	COG1129	ABC transporter
G9272_RS42070	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9272_RS42075	COG2188	Transcriptional regulator
G9272_RS42090	COG2409	Drug exporters of the RND superfamily
G9272_RS42100	COG2197	response regulator
G9272_RS42105	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G9272_RS42110	COG3386	PFAM SMP-30 Gluconolaconase
G9272_RS42130	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G9272_RS42150	COG1609	Transcriptional regulator
G9272_RS42155	COG1879	ABC-type sugar transport system periplasmic component
G9272_RS42160	COG1129	ABC transporter
G9272_RS42165	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9272_RS42170	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9272_RS42180	COG1017	nitric oxide dioxygenase activity
G9272_RS42180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9272_RS42225	COG1175	transmembrane transport
G9272_RS42230	COG0395	ABC-type sugar transport system, permease component
G9272_RS42235	COG0366	Alpha amylase catalytic
G9272_RS42240	COG0477	Major facilitator Superfamily
G9272_RS42270	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G9272_RS42305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G9272_RS42315	COG0300	oxidoreductase activity
G9272_RS42375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G9272_RS42380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G9272_RS42395	COG0671	phosphoesterase, PA-phosphatase related
G9272_RS42415	COG1733	regulation of RNA biosynthetic process
G9272_RS42430	COG0667	Aldo Keto reductase
G9272_RS42455	COG1064	alcohol dehydrogenase
G9272_RS42495	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS42515	COG0395	ABC-type sugar transport system, permease component
G9272_RS42520	COG1063	alcohol dehydrogenase
G9272_RS42525	COG1063	alcohol dehydrogenase
G9272_RS42535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9272_RS42565	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS42620	COG1252	NADH dehydrogenase
G9272_RS42675	COG2197	response regulator
G9272_RS42690	COG1131	(ABC) transporter
G9272_RS42720	COG2226	methyltransferase
G9272_RS42735	COG1136	(ABC) transporter
G9272_RS42745	COG1653	transport
G9272_RS42750	COG0366	Alpha amylase catalytic
G9272_RS42760	COG1175	transmembrane transport
G9272_RS42765	COG0395	ABC-type sugar transport system, permease component
G9272_RS42785	COG1191	sigma factor activity
G9272_RS42800	COG0477	Major facilitator Superfamily
G9272_RS42800	COG2814	Major facilitator Superfamily
G9272_RS42810	COG2159	amidohydrolase
G9272_RS42815	COG0745	RESPONSE REGULATOR receiver
G9272_RS42820	COG5002	protein histidine kinase activity
G9272_RS42820	COG5000	phosphorelay sensor kinase activity
G9272_RS42850	COG2208	phosphoserine phosphatase activity
G9272_RS42955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9272_RS43025	COG4638	Rieske (2fe-2S)
G9272_RS43040	COG2192	nodulation
G9272_RS43060	COG0546	phosphoglycolate phosphatase activity
G9272_RS43065	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G9272_RS43075	COG0463	Glycosyl transferase, family 2
G9272_RS43130	COG2255	four-way junction helicase activity
G9272_RS43140	COG2205	protein histidine kinase activity
G9272_RS43145	COG0745	RESPONSE REGULATOR receiver
G9272_RS43195	COG0367	asparagine synthase
G9272_RS43200	COG2264	protein methyltransferase activity
G9272_RS43270	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G9272_RS43310	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G9272_RS43320	COG1028	Short-chain dehydrogenase reductase Sdr
G9272_RS43320	COG0604	alcohol dehydrogenase
G9272_RS43320	COG3321	synthase
G9272_RS43365	COG1733	regulation of RNA biosynthetic process
G9272_RS43380	COG1136	(ABC) transporter
G9272_RS43380	COG0577	efflux transmembrane transporter activity
G9272_RS43400	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G9272_RS43445	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G9272_RS43460	COG3655	Transcriptional regulator
G9272_RS43465	COG4221	oxidoreductase activity
G9272_RS43535	COG0024	Methionine aminopeptidase
G9272_RS43540	COG0667	Aldo Keto reductase
G9272_RS43555	COG0477	Major facilitator Superfamily
G9272_RS43565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G9272_RS43595	COG0583	DNA-binding transcription factor activity
G9272_RS43615	COG0148	phosphopyruvate hydratase activity
G9272_RS43625	COG1609	Transcriptional regulator
G9272_RS43630	COG0179	Fumarylacetoacetate (FAA) hydrolase
G9272_RS43635	COG2271	Major facilitator Superfamily
G9272_RS43640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G9272_RS43675	COG0515	serine threonine protein kinase
G9272_RS43675	COG2815	serine threonine protein kinase
G9272_RS43680	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G9272_RS43695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G9272_RS43745	COG0583	DNA-binding transcription factor activity
G9272_RS43810	COG2249	NAD(P)H dehydrogenase (quinone) activity
G9272_RS43815	COG0667	Aldo Keto reductase
G9272_RS43825	COG4221	oxidoreductase activity
G9272_RS43885	COG1595	DNA-templated transcription, initiation
G9272_RS43905	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G9272_RS43965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G9272_RS43995	COG2181	nitrate reductase activity
G9272_RS43995	COG0247	lactate metabolic process
G9272_RS44015	COG0702	epimerase
G9272_RS44045	COG3903	Transcriptional regulator
G9272_RS44045	COG3629	intracellular signal transduction
G9272_RS44055	COG3424	synthase
G9272_RS44065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G9272_RS44070	COG2345	Transcriptional regulator
G9272_RS44080	COG0655	NAD(P)H dehydrogenase (quinone) activity
G9272_RS44085	COG0318	PFAM AMP-dependent synthetase and ligase
G9272_RS44125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G9272_RS44130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9272_RS44140	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G9272_RS44195	COG3425	synthase
G9272_RS44215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G9272_RS44280	COG2124	cytochrome p450
G9272_RS44290	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9272_RS44320	COG2226	methyltransferase
G9272_RS44320	COG2867	negative regulation of translational initiation
G9272_RS44325	COG2124	cytochrome p450
G9272_RS44340	COG4249	Peptidase C14 caspase catalytic subunit p20
G9272_RS44340	COG2319	Wd-40 repeat
G9272_RS44350	COG2132	Multicopper oxidase
G9272_RS44355	COG0477	Major facilitator Superfamily
G9272_RS44360	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G9272_RS44370	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G9272_RS44400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G9272_RS44410	COG0778	Nitroreductase
G9272_RS44460	COG0456	acetyltransferase
G9272_RS44465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G9272_RS44470	COG2814	Major facilitator Superfamily
G9272_RS44475	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G9272_RS44480	COG0254	rRNA binding
G9272_RS44495	COG1522	sequence-specific DNA binding
G9272_RS45065	COG1535	isochorismatase
G9272_RS45065	COG3433	isochorismatase activity
G9272_RS45155	COG0604	alcohol dehydrogenase
G9272_RS45155	COG3321	synthase
G9272_RS45200	COG3629	intracellular signal transduction
G9272_RS45410	COG0515	serine threonine protein kinase
G9272_RS45450	COG3629	intracellular signal transduction
G9272_RS45450	COG3903	Transcriptional regulator
G9272_RS45595	COG2197	response regulator
G9272_RS45755	COG0778	Nitroreductase
G9272_RS45775	COG2086	electron transfer activity
G9272_RS45780	COG2086	electron transfer activity