locus-tag	class	description
G3H79_RS00040	COG2814	Major facilitator Superfamily
G3H79_RS00075	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS00085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3H79_RS00105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3H79_RS00115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G3H79_RS00120	COG3629	intracellular signal transduction
G3H79_RS00130	COG0477	Major facilitator Superfamily
G3H79_RS00140	COG3321	synthase
G3H79_RS00140	COG0604	alcohol dehydrogenase
G3H79_RS00180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3H79_RS00185	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS00195	COG3629	intracellular signal transduction
G3H79_RS00205	COG2867	negative regulation of translational initiation
G3H79_RS00225	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3H79_RS00235	COG3629	intracellular signal transduction
G3H79_RS00265	COG1278	Cold shock
G3H79_RS00270	COG0494	nUDIX hydrolase
G3H79_RS00275	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS00285	COG2378	regulation of single-species biofilm formation
G3H79_RS00295	COG1309	transcriptional regulator
G3H79_RS00300	COG0154	amidase activity
G3H79_RS00315	COG0702	epimerase
G3H79_RS00320	COG0515	serine threonine protein kinase
G3H79_RS00330	COG1132	(ABC) transporter
G3H79_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS00380	COG0148	phosphopyruvate hydratase activity
G3H79_RS00405	COG0531	amino acid
G3H79_RS00410	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G3H79_RS00460	COG4977	sequence-specific DNA binding
G3H79_RS00470	COG2205	protein histidine kinase activity
G3H79_RS00475	COG0745	RESPONSE REGULATOR receiver
G3H79_RS00490	COG1136	(ABC) transporter
G3H79_RS00495	COG1136	(ABC) transporter
G3H79_RS00495	COG0577	efflux transmembrane transporter activity
G3H79_RS00500	COG2267	carboxylic ester hydrolase activity
G3H79_RS00515	COG1846	Transcriptional regulator
G3H79_RS00560	COG0667	Aldo Keto reductase
G3H79_RS00575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G3H79_RS00585	COG2010	Cytochrome c
G3H79_RS00585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3H79_RS00675	COG1819	glycosyl
G3H79_RS00695	COG4585	Histidine kinase
G3H79_RS00700	COG0535	radical SAM domain protein
G3H79_RS00710	COG0515	serine threonine protein kinase
G3H79_RS00755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G3H79_RS00765	COG0346	lactoylglutathione lyase activity
G3H79_RS00785	COG3345	alpha-galactosidase
G3H79_RS00795	COG2124	cytochrome p450
G3H79_RS00850	COG2080	2 iron, 2 sulfur cluster binding
G3H79_RS00855	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G3H79_RS00860	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3H79_RS00895	COG1472	Belongs to the glycosyl hydrolase 3 family
G3H79_RS00950	COG2340	Cysteine-rich secretory protein family
G3H79_RS00975	COG0745	RESPONSE REGULATOR receiver
G3H79_RS00980	COG2205	protein histidine kinase activity
G3H79_RS01000	COG1191	sigma factor activity
G3H79_RS01045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS01050	COG2267	carboxylic ester hydrolase activity
G3H79_RS01070	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS01130	COG1597	lipid kinase activity
G3H79_RS01140	COG1280	lysine exporter protein (LysE YggA)
G3H79_RS01150	COG2124	cytochrome p450
G3H79_RS01155	COG2124	cytochrome p450
G3H79_RS01205	COG0395	ABC-type sugar transport system, permease component
G3H79_RS01210	COG1175	transmembrane transport
G3H79_RS01250	COG2188	Transcriptional regulator
G3H79_RS01275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3H79_RS01285	COG1396	sequence-specific DNA binding
G3H79_RS01295	COG0740	serine-type endopeptidase activity
G3H79_RS01300	COG0740	serine-type endopeptidase activity
G3H79_RS01315	COG3540	Alkaline phosphatase
G3H79_RS01325	COG2197	response regulator
G3H79_RS01365	COG2233	PERMEase
G3H79_RS01370	COG0640	Transcriptional regulator
G3H79_RS01375	COG1902	pentaerythritol trinitrate reductase activity
G3H79_RS01380	COG1228	amidohydrolase
G3H79_RS01440	COG1940	carbohydrate kinase activity
G3H79_RS01455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3H79_RS01465	COG2040	homocysteine
G3H79_RS01475	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G3H79_RS01480	COG2971	BadF BadG BcrA BcrD
G3H79_RS01490	COG2706	6-phosphogluconolactonase activity
G3H79_RS01510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3H79_RS01540	COG1554	hydrolase, family 65, central catalytic
G3H79_RS01545	COG0515	serine threonine protein kinase
G3H79_RS01560	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G3H79_RS01585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G3H79_RS01595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G3H79_RS01610	COG2326	polyphosphate kinase activity
G3H79_RS01660	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G3H79_RS01665	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G3H79_RS01670	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
G3H79_RS01695	COG1126	abc transporter atp-binding protein
G3H79_RS01715	COG3608	succinylglutamate desuccinylase aspartoacylase
G3H79_RS01715	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G3H79_RS01720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3H79_RS01725	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G3H79_RS01730	COG2080	2 iron, 2 sulfur cluster binding
G3H79_RS01740	COG0022	dehydrogenase e1 component
G3H79_RS01745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G3H79_RS01750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3H79_RS01770	COG1022	Amp-dependent synthetase and ligase
G3H79_RS01775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3H79_RS01790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3H79_RS01800	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3H79_RS01810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3H79_RS01820	COG4221	oxidoreductase activity
G3H79_RS01860	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS01865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3H79_RS01890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3H79_RS01900	COG2986	histidine ammonia-lyase
G3H79_RS01905	COG1132	(ABC) transporter
G3H79_RS01910	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS01925	COG0515	serine threonine protein kinase
G3H79_RS01955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3H79_RS01980	COG0432	Pfam Uncharacterised protein family UPF0047
G3H79_RS01985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3H79_RS01990	COG1116	anion transmembrane transporter activity
G3H79_RS02055	COG1132	(ABC) transporter
G3H79_RS02095	COG1132	(ABC) transporter
G3H79_RS02100	COG0583	DNA-binding transcription factor activity
G3H79_RS02105	COG0473	3-isopropylmalate dehydrogenase activity
G3H79_RS02120	COG1132	(ABC) transporter
G3H79_RS02125	COG1132	(ABC) transporter
G3H79_RS02140	COG1946	Acyl-CoA thioesterase
G3H79_RS02155	COG2018	Roadblock/LC7 domain
G3H79_RS02230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G3H79_RS02275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G3H79_RS02295	COG2115	Belongs to the xylose isomerase family
G3H79_RS02300	COG1070	Carbohydrate kinase
G3H79_RS02305	COG1940	carbohydrate kinase activity
G3H79_RS02320	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS02405	COG0604	alcohol dehydrogenase
G3H79_RS02405	COG3321	synthase
G3H79_RS02460	COG1595	DNA-templated transcription, initiation
G3H79_RS02500	COG1473	amidohydrolase
G3H79_RS02550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3H79_RS02560	COG2409	Drug exporters of the RND superfamily
G3H79_RS02610	COG2124	cytochrome p450
G3H79_RS02625	COG3845	ABC transporter
G3H79_RS02650	COG4044	May play a role in the intracellular transport of hydrophobic ligands
G3H79_RS02705	COG0588	phosphoglycerate mutase activity
G3H79_RS02710	COG1070	Carbohydrate kinase
G3H79_RS02720	COG2814	Major facilitator Superfamily
G3H79_RS02725	COG1349	DNA-binding transcription factor activity
G3H79_RS02740	COG0444	Belongs to the ABC transporter superfamily
G3H79_RS02745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3H79_RS02750	COG0601	transmembrane transport
G3H79_RS02760	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS02765	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS02780	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS02785	COG1024	Enoyl-CoA hydratase
G3H79_RS02800	COG0247	lactate metabolic process
G3H79_RS02805	COG1139	Iron-sulfur cluster binding protein
G3H79_RS02810	COG1556	Lactate utilization protein
G3H79_RS02820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G3H79_RS02830	COG1174	glycine betaine transport
G3H79_RS02835	COG1174	glycine betaine transport
G3H79_RS02865	COG1175	transmembrane transport
G3H79_RS02870	COG0395	ABC-type sugar transport system, permease component
G3H79_RS02875	COG0366	Alpha amylase catalytic
G3H79_RS02895	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3H79_RS02925	COG0596	Alpha beta hydrolase
G3H79_RS02980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3H79_RS03010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3H79_RS03015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS03030	COG0367	asparagine synthase
G3H79_RS03065	COG0596	Alpha beta hydrolase
G3H79_RS03075	COG1683	Conserved Protein
G3H79_RS03110	COG0702	epimerase
G3H79_RS03135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G3H79_RS03140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G3H79_RS03175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3H79_RS03180	COG1609	Transcriptional regulator
G3H79_RS03200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3H79_RS03205	COG0121	glutamine amidotransferase
G3H79_RS03210	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
G3H79_RS03215	COG2182	Extracellular solute-binding protein
G3H79_RS03225	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G3H79_RS03240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS03265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3H79_RS03270	COG1053	succinate dehydrogenase
G3H79_RS03280	COG0583	DNA-binding transcription factor activity
G3H79_RS03330	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G3H79_RS03330	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G3H79_RS03340	COG0531	amino acid
G3H79_RS03370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G3H79_RS03400	COG1131	(ABC) transporter
G3H79_RS03405	COG4585	Histidine kinase
G3H79_RS03410	COG2197	response regulator
G3H79_RS03420	COG3152	Membrane
G3H79_RS03440	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS03455	COG1129	ABC transporter
G3H79_RS03465	COG2186	Transcriptional regulator
G3H79_RS03470	COG3903	Transcriptional regulator
G3H79_RS03470	COG3629	intracellular signal transduction
G3H79_RS03485	COG0395	ABC-type sugar transport system, permease component
G3H79_RS03490	COG1175	transmembrane transport
G3H79_RS03495	COG1653	transport
G3H79_RS03500	COG1609	Transcriptional regulator
G3H79_RS03530	COG3525	Glycosyl hydrolase, family 20, catalytic domain
G3H79_RS03540	COG0406	alpha-ribazole phosphatase activity
G3H79_RS03575	COG3537	Alpha-1,2-mannosidase
G3H79_RS03585	COG1609	Transcriptional regulator
G3H79_RS03590	COG1879	ABC-type sugar transport system periplasmic component
G3H79_RS03595	COG1129	ABC transporter
G3H79_RS03600	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3H79_RS03605	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3H79_RS03610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G3H79_RS03615	COG0297	glycogen (starch) synthase activity
G3H79_RS03635	COG3458	cephalosporin-C deacetylase activity
G3H79_RS03640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G3H79_RS03665	COG1278	Cold shock
G3H79_RS03685	COG2409	Drug exporters of the RND superfamily
G3H79_RS03700	COG4585	Histidine kinase
G3H79_RS03705	COG2197	response regulator
G3H79_RS03710	COG4585	Histidine kinase
G3H79_RS03730	COG2124	cytochrome p450
G3H79_RS03740	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS03850	COG3842	ATPase activity
G3H79_RS03860	COG0463	Glycosyl transferase, family 2
G3H79_RS03875	COG1132	(ABC) transporter
G3H79_RS03880	COG1472	Belongs to the glycosyl hydrolase 3 family
G3H79_RS03895	COG2130	NADP-dependent
G3H79_RS03925	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS03970	COG0183	Belongs to the thiolase family
G3H79_RS03985	COG3321	synthase
G3H79_RS03985	COG0604	alcohol dehydrogenase
G3H79_RS03995	COG2124	cytochrome p450
G3H79_RS04000	COG0512	Glutamine amidotransferase of anthranilate synthase
G3H79_RS04000	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G3H79_RS04010	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
G3H79_RS04020	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS04055	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS04065	COG2340	Cysteine-rich secretory protein family
G3H79_RS04080	COG0395	ABC-type sugar transport system, permease component
G3H79_RS04085	COG1175	transmembrane transport
G3H79_RS04095	COG1940	carbohydrate kinase activity
G3H79_RS04115	COG1917	Cupin 2, conserved barrel domain protein
G3H79_RS04115	COG4977	sequence-specific DNA binding
G3H79_RS04120	COG0668	transmembrane transport
G3H79_RS04125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3H79_RS04125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3H79_RS04130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G3H79_RS04140	COG0842	Transport permease protein
G3H79_RS04140	COG1129	ABC transporter
G3H79_RS04145	COG1309	transcriptional regulator
G3H79_RS04150	COG3629	intracellular signal transduction
G3H79_RS04155	COG3321	synthase
G3H79_RS04155	COG3321	synthase
G3H79_RS04160	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS04190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3H79_RS04195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3H79_RS04200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3H79_RS04205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3H79_RS04210	COG0156	8-amino-7-oxononanoate synthase activity
G3H79_RS04215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3H79_RS04230	COG2890	protein-(glutamine-N5) methyltransferase activity
G3H79_RS04245	COG0248	Ppx GppA phosphatase
G3H79_RS04250	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3H79_RS04275	COG2409	Drug exporters of the RND superfamily
G3H79_RS04285	COG2124	cytochrome p450
G3H79_RS04300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3H79_RS04305	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G3H79_RS04310	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G3H79_RS04390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3H79_RS04410	COG0308	aminopeptidase N
G3H79_RS04425	COG3959	Transketolase, thiamine diphosphate binding domain
G3H79_RS04430	COG3958	Transketolase
G3H79_RS04460	COG1116	anion transmembrane transporter activity
G3H79_RS04470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3H79_RS04475	COG0583	DNA-binding transcription factor activity
G3H79_RS04485	COG1063	alcohol dehydrogenase
G3H79_RS04490	COG0673	inositol 2-dehydrogenase activity
G3H79_RS04545	COG2755	lipolytic protein G-D-S-L family
G3H79_RS04575	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G3H79_RS04580	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G3H79_RS04595	COG1657	PFAM Prenyltransferase squalene oxidase
G3H79_RS04605	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
G3H79_RS04615	COG1562	ergosterol biosynthetic process
G3H79_RS04620	COG1134	teichoic acid transport
G3H79_RS04655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G3H79_RS04670	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
G3H79_RS04685	COG1024	Enoyl-CoA hydratase
G3H79_RS04695	COG4977	sequence-specific DNA binding
G3H79_RS04705	COG2183	response to ionizing radiation
G3H79_RS04710	COG0488	(ABC) transporter
G3H79_RS04725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3H79_RS04735	COG2936	dipeptidyl-peptidase activity
G3H79_RS04750	COG1113	amino acid transport
G3H79_RS04760	COG0789	Transcriptional regulator
G3H79_RS04765	COG1024	Enoyl-CoA hydratase
G3H79_RS04765	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3H79_RS04770	COG0183	Belongs to the thiolase family
G3H79_RS04775	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS04780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS04785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3H79_RS04795	COG3268	Saccharopine dehydrogenase
G3H79_RS04800	COG1515	deoxyribonuclease V activity
G3H79_RS04805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3H79_RS04830	COG0488	(ABC) transporter
G3H79_RS04835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3H79_RS04915	COG1793	dna ligase
G3H79_RS04930	COG1846	Transcriptional regulator
G3H79_RS04945	COG3485	protocatechuate 3,4-dioxygenase
G3H79_RS04950	COG3485	protocatechuate 3,4-dioxygenase
G3H79_RS04955	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G3H79_RS04970	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS04980	COG1024	Enoyl-CoA hydratase
G3H79_RS05005	COG0183	Belongs to the thiolase family
G3H79_RS05010	COG1309	transcriptional regulator
G3H79_RS05020	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS05025	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS05035	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G3H79_RS05065	COG0525	valine-tRNA ligase activity
G3H79_RS05070	COG3511	phospholipase C
G3H79_RS05095	COG1486	melibiose metabolic process
G3H79_RS05105	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3H79_RS05110	COG3246	L-lysine catabolic process to acetate
G3H79_RS05120	COG2814	Major facilitator Superfamily
G3H79_RS05150	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G3H79_RS05155	COG4948	Mandelate Racemase Muconate Lactonizing
G3H79_RS05165	COG0475	glutathione-regulated potassium exporter activity
G3H79_RS05220	COG1063	alcohol dehydrogenase
G3H79_RS05225	COG1472	Belongs to the glycosyl hydrolase 3 family
G3H79_RS05230	COG2124	cytochrome p450
G3H79_RS05245	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS05255	COG0045	succinate-CoA ligase (ADP-forming) activity
G3H79_RS05265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3H79_RS05275	COG2223	nitrite transmembrane transporter activity
G3H79_RS05315	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3H79_RS05345	COG0673	inositol 2-dehydrogenase activity
G3H79_RS05355	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3H79_RS05360	COG1129	ABC transporter
G3H79_RS05365	COG1940	carbohydrate kinase activity
G3H79_RS05375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3H79_RS05395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3H79_RS05400	COG3383	formate dehydrogenase (NAD+) activity
G3H79_RS05415	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G3H79_RS05445	COG0477	Major facilitator Superfamily
G3H79_RS05450	COG1022	Amp-dependent synthetase and ligase
G3H79_RS05480	COG3469	chitinase activity
G3H79_RS05510	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G3H79_RS05555	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G3H79_RS05555	COG4106	trans-aconitate 2-methyltransferase activity
G3H79_RS05560	COG2154	pterin-4-alpha-carbinolamine dehydratase
G3H79_RS05590	COG0531	amino acid
G3H79_RS05645	COG0516	GMP reductase activity
G3H79_RS05645	COG0517	IMP dehydrogenase activity
G3H79_RS05660	COG0488	(ABC) transporter
G3H79_RS05720	COG1252	NADH dehydrogenase
G3H79_RS05745	COG0457	Tetratricopeptide repeat
G3H79_RS05775	COG1619	proteins homologs of microcin C7 resistance protein MccF
G3H79_RS05785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3H79_RS05790	COG2362	D-Aminopeptidase
G3H79_RS05885	COG0546	phosphoglycolate phosphatase activity
G3H79_RS05895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3H79_RS05900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G3H79_RS05915	COG0367	asparagine synthase
G3H79_RS05930	COG2197	response regulator
G3H79_RS05935	COG4585	Histidine kinase
G3H79_RS05990	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3H79_RS06000	COG0604	alcohol dehydrogenase
G3H79_RS06005	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3H79_RS06005	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3H79_RS06010	COG2301	Belongs to the HpcH HpaI aldolase family
G3H79_RS06020	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS06025	COG0688	phosphatidylethanolamine metabolic process
G3H79_RS06035	COG1929	Belongs to the glycerate kinase type-1 family
G3H79_RS06090	COG0483	inositol monophosphate 1-phosphatase activity
G3H79_RS06120	COG2124	cytochrome p450
G3H79_RS06155	COG2197	response regulator
G3H79_RS06170	COG2226	methyltransferase
G3H79_RS06175	COG1953	Uracil, thiamine, allantoin
G3H79_RS06185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G3H79_RS06190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3H79_RS06230	COG0405	Gamma-glutamyltransferase
G3H79_RS06240	COG1376	ErfK ybiS ycfS ynhG family protein
G3H79_RS06250	COG0765	amino acid transport
G3H79_RS06255	COG0765	amino acid transport
G3H79_RS06260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3H79_RS06265	COG1126	abc transporter atp-binding protein
G3H79_RS06290	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G3H79_RS06295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3H79_RS06325	COG1940	carbohydrate kinase activity
G3H79_RS06350	COG2188	Transcriptional regulator
G3H79_RS06355	COG0673	inositol 2-dehydrogenase activity
G3H79_RS06370	COG2197	response regulator
G3H79_RS06405	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS06410	COG4266	Belongs to the allantoicase family
G3H79_RS06415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G3H79_RS06420	COG1414	Transcriptional regulator
G3H79_RS06430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3H79_RS06475	COG0436	Aminotransferase
G3H79_RS06485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3H79_RS06495	COG0588	phosphoglycerate mutase activity
G3H79_RS06510	COG0667	Aldo Keto reductase
G3H79_RS06535	COG4249	Peptidase C14 caspase catalytic subunit p20
G3H79_RS06535	COG2319	Wd-40 repeat
G3H79_RS06550	COG5183	chlorophyll binding
G3H79_RS06550	COG2133	pyrroloquinoline quinone binding
G3H79_RS06585	COG2233	PERMEase
G3H79_RS06595	COG2233	PERMEase
G3H79_RS06605	COG2351	hydroxyisourate hydrolase activity
G3H79_RS06625	COG3622	Belongs to the hyi family
G3H79_RS06630	COG2084	Dehydrogenase
G3H79_RS06635	COG0753	catalase activity
G3H79_RS06650	COG3960	tartronate-semialdehyde synthase activity
G3H79_RS06660	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS06665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3H79_RS06670	COG2197	response regulator
G3H79_RS06685	COG0598	Magnesium transport protein CorA
G3H79_RS06715	COG1484	DNA-dependent DNA replication
G3H79_RS06735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3H79_RS06830	COG0598	Magnesium transport protein CorA
G3H79_RS06840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G3H79_RS06845	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
G3H79_RS06855	COG1216	Glycosyl transferase, family 2
G3H79_RS06865	COG4310	Domain of unknown function (DUF2172)
G3H79_RS06880	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G3H79_RS06890	COG0438	transferase activity, transferring glycosyl groups
G3H79_RS06910	COG1063	alcohol dehydrogenase
G3H79_RS06935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G3H79_RS06945	COG1316	TRANSCRIPTIONal
G3H79_RS06960	COG0583	DNA-binding transcription factor activity
G3H79_RS06965	COG2814	Major facilitator Superfamily
G3H79_RS06985	COG2972	Histidine kinase
G3H79_RS06985	COG2205	protein histidine kinase activity
G3H79_RS06990	COG0745	RESPONSE REGULATOR receiver
G3H79_RS07025	COG1309	transcriptional regulator
G3H79_RS07040	COG2252	PERMEase
G3H79_RS07045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3H79_RS07070	COG1802	Transcriptional regulator
G3H79_RS07095	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G3H79_RS07100	COG0028	Belongs to the TPP enzyme family
G3H79_RS07140	COG1162	GTPase activity
G3H79_RS07160	COG1051	belongs to the nudix hydrolase family
G3H79_RS07180	COG0702	epimerase
G3H79_RS07190	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS07215	COG0175	sulfate reduction
G3H79_RS07220	COG0529	Catalyzes the synthesis of activated sulfate
G3H79_RS07245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3H79_RS07260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3H79_RS07290	COG2364	Membrane
G3H79_RS07295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3H79_RS07370	COG1716	ATPase activity
G3H79_RS07375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G3H79_RS07380	COG3281	Trehalose synthase
G3H79_RS07390	COG0366	Alpha amylase catalytic
G3H79_RS07420	COG0667	Aldo Keto reductase
G3H79_RS07430	COG1280	lysine exporter protein (LysE YggA)
G3H79_RS07435	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G3H79_RS07445	COG0583	DNA-binding transcription factor activity
G3H79_RS07450	COG0504	CTP synthase activity
G3H79_RS07480	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G3H79_RS07490	COG0443	Heat shock 70 kDa protein
G3H79_RS07545	COG3629	intracellular signal transduction
G3H79_RS07545	COG3903	Transcriptional regulator
G3H79_RS07560	COG3903	Transcriptional regulator
G3H79_RS07560	COG3629	intracellular signal transduction
G3H79_RS07570	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3H79_RS07575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G3H79_RS07600	COG2264	protein methyltransferase activity
G3H79_RS07635	COG2226	methyltransferase
G3H79_RS07640	COG0076	glutamate decarboxylase activity
G3H79_RS07655	COG1131	(ABC) transporter
G3H79_RS07730	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3H79_RS07750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3H79_RS07770	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G3H79_RS07785	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G3H79_RS07790	COG0183	Belongs to the thiolase family
G3H79_RS07795	COG1024	Enoyl-CoA hydratase
G3H79_RS07795	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3H79_RS07820	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G3H79_RS07830	COG2843	Capsule synthesis protein
G3H79_RS07840	COG0531	amino acid
G3H79_RS07845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G3H79_RS07850	COG4214	carbohydrate transport
G3H79_RS07860	COG4213	ABC transporter substrate-binding protein
G3H79_RS07865	COG1940	carbohydrate kinase activity
G3H79_RS07870	COG0395	ABC-type sugar transport system, permease component
G3H79_RS07875	COG1175	transmembrane transport
G3H79_RS07885	COG0583	DNA-binding transcription factor activity
G3H79_RS07910	COG2814	Major facilitator Superfamily
G3H79_RS07940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G3H79_RS07955	COG1609	Transcriptional regulator
G3H79_RS07965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G3H79_RS08010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G3H79_RS08045	COG1024	Enoyl-CoA hydratase
G3H79_RS08055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G3H79_RS08060	COG2235	arginine
G3H79_RS08065	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G3H79_RS08115	COG1799	cell septum assembly
G3H79_RS08135	COG0577	efflux transmembrane transporter activity
G3H79_RS08135	COG1136	(ABC) transporter
G3H79_RS08150	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS08155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3H79_RS08195	COG2197	response regulator
G3H79_RS08210	COG0604	alcohol dehydrogenase
G3H79_RS08210	COG3321	synthase
G3H79_RS08240	COG3835	regulator
G3H79_RS08250	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3H79_RS08250	COG2080	2 iron, 2 sulfur cluster binding
G3H79_RS08270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G3H79_RS08275	COG0531	amino acid
G3H79_RS08295	COG0569	domain protein
G3H79_RS08330	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G3H79_RS08335	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G3H79_RS08340	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
G3H79_RS08355	COG0756	dUTP diphosphatase activity
G3H79_RS08380	COG2205	protein histidine kinase activity
G3H79_RS08385	COG0745	RESPONSE REGULATOR receiver
G3H79_RS08430	COG1435	thymidine kinase activity
G3H79_RS08450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3H79_RS08455	COG1802	Transcriptional regulator
G3H79_RS08470	COG0612	Peptidase, M16
G3H79_RS08475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G3H79_RS08505	COG0372	Belongs to the citrate synthase family
G3H79_RS08520	COG3290	protein histidine kinase activity
G3H79_RS08525	COG4565	transcriptional regulatory protein
G3H79_RS08530	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3H79_RS08540	COG2197	response regulator
G3H79_RS08545	COG4585	Histidine kinase
G3H79_RS08555	COG0187	DNA topoisomerase II activity
G3H79_RS08570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G3H79_RS08575	COG2186	Transcriptional regulator
G3H79_RS08615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3H79_RS08640	COG1120	ATPase activity
G3H79_RS08645	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3H79_RS08650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3H79_RS08655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3H79_RS08660	COG2375	cellular response to nickel ion
G3H79_RS08665	COG1535	isochorismatase
G3H79_RS08665	COG3433	isochorismatase activity
G3H79_RS08670	COG3433	isochorismatase activity
G3H79_RS08670	COG1535	isochorismatase
G3H79_RS08675	COG1021	2,3-dihydroxybenzoate-AMP ligase
G3H79_RS08680	COG1169	isochorismate synthase
G3H79_RS08685	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS08690	COG0514	ATP-dependent DNA helicase (RecQ)
G3H79_RS08705	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G3H79_RS08725	COG0588	phosphoglycerate mutase activity
G3H79_RS08745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3H79_RS08750	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G3H79_RS08795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G3H79_RS08805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3H79_RS08810	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G3H79_RS08820	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G3H79_RS08840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G3H79_RS08855	COG1595	DNA-templated transcription, initiation
G3H79_RS08895	COG2205	protein histidine kinase activity
G3H79_RS08905	COG1126	abc transporter atp-binding protein
G3H79_RS08910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3H79_RS08915	COG0765	amino acid transport
G3H79_RS08920	COG0765	amino acid transport
G3H79_RS08935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3H79_RS08955	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G3H79_RS08960	COG0628	permease
G3H79_RS08985	COG1917	Cupin 2, conserved barrel domain protein
G3H79_RS08985	COG2207	Transcriptional regulator
G3H79_RS08990	COG1201	RNA secondary structure unwinding
G3H79_RS08995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G3H79_RS09010	COG0783	Belongs to the Dps family
G3H79_RS09015	COG1396	sequence-specific DNA binding
G3H79_RS09020	COG1058	Belongs to the CinA family
G3H79_RS09020	COG1546	Belongs to the CinA family
G3H79_RS09030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G3H79_RS09040	COG1674	ftsk spoiiie
G3H79_RS09050	COG3850	Histidine kinase
G3H79_RS09050	COG3437	response regulator, receiver
G3H79_RS09050	COG4999	Histidine kinase
G3H79_RS09050	COG2205	protein histidine kinase activity
G3H79_RS09055	COG2770	Histidine kinase
G3H79_RS09055	COG2208	phosphoserine phosphatase activity
G3H79_RS09085	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G3H79_RS09090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3H79_RS09095	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
G3H79_RS09115	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G3H79_RS09120	COG0612	Peptidase, M16
G3H79_RS09125	COG1185	polyribonucleotide nucleotidyltransferase activity
G3H79_RS09130	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G3H79_RS09145	COG1674	ftsk spoiiie
G3H79_RS09195	COG1404	Belongs to the peptidase S8 family
G3H79_RS09215	COG1404	Belongs to the peptidase S8 family
G3H79_RS09220	COG3266	domain, Protein
G3H79_RS09235	COG0455	bacterial-type flagellum organization
G3H79_RS09245	COG0601	transmembrane transport
G3H79_RS09250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3H79_RS09275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G3H79_RS09280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G3H79_RS09290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G3H79_RS09305	COG0779	Required for maturation of 30S ribosomal subunits
G3H79_RS09330	COG0442	prolyl-tRNA aminoacylation
G3H79_RS09355	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G3H79_RS09360	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3H79_RS09365	COG3842	ATPase activity
G3H79_RS09375	COG1609	Transcriptional regulator
G3H79_RS09380	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G3H79_RS09385	COG0750	zinc metalloprotease
G3H79_RS09390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G3H79_RS09400	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS09405	COG2508	Transcriptional regulator
G3H79_RS09445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3H79_RS09450	COG1177	transmembrane transport
G3H79_RS09455	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3H79_RS09460	COG3842	ATPase activity
G3H79_RS09470	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS09480	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3H79_RS09485	COG0584	glycerophosphoryl diester phosphodiesterase
G3H79_RS09500	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS09505	COG1309	transcriptional regulator
G3H79_RS09510	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
G3H79_RS09515	COG2271	Major facilitator Superfamily
G3H79_RS09520	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS09525	COG0277	FAD linked oxidase domain protein
G3H79_RS09530	COG1070	Carbohydrate kinase
G3H79_RS09545	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS09555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3H79_RS09560	COG4181	ATPase activity
G3H79_RS09585	COG3842	ATPase activity
G3H79_RS09600	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G3H79_RS09605	COG0575	Belongs to the CDS family
G3H79_RS09610	COG0233	cytoplasmic translational termination
G3H79_RS09615	COG0528	UMP kinase activity
G3H79_RS09620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G3H79_RS09625	COG0052	Belongs to the universal ribosomal protein uS2 family
G3H79_RS09630	COG4942	peptidase
G3H79_RS09640	COG1191	sigma factor activity
G3H79_RS09655	COG0792	nuclease activity
G3H79_RS09675	COG0681	Belongs to the peptidase S26 family
G3H79_RS09680	COG0681	Belongs to the peptidase S26 family
G3H79_RS09685	COG0681	Belongs to the peptidase S26 family
G3H79_RS09690	COG0335	large ribosomal subunit rRNA binding
G3H79_RS09695	COG0336	Belongs to the RNA methyltransferase TrmD family
G3H79_RS09700	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G3H79_RS09705	COG1837	Belongs to the UPF0109 family
G3H79_RS09710	COG0228	four-way junction DNA binding
G3H79_RS09720	COG0442	prolyl-tRNA aminoacylation
G3H79_RS09730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3H79_RS09740	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G3H79_RS09780	COG0477	Major facilitator Superfamily
G3H79_RS09785	COG1196	nuclear chromosome segregation
G3H79_RS09795	COG1254	Belongs to the acylphosphatase family
G3H79_RS09800	COG2340	Cysteine-rich secretory protein family
G3H79_RS09810	COG1733	regulation of RNA biosynthetic process
G3H79_RS09815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G3H79_RS09820	COG0571	ribonuclease III activity
G3H79_RS09825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G3H79_RS09840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G3H79_RS09845	COG0742	ribosomal rna small subunit methyltransferase
G3H79_RS09855	COG1461	Dihydroxyacetone kinase
G3H79_RS09860	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G3H79_RS09875	COG0351	phosphomethylpyrimidine kinase
G3H79_RS09895	COG1181	Belongs to the D-alanine--D-alanine ligase family
G3H79_RS09900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G3H79_RS09910	COG1920	GTP binding
G3H79_RS09920	COG0776	regulation of translation
G3H79_RS09930	COG0066	3-isopropylmalate dehydratase activity
G3H79_RS09935	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G3H79_RS09940	COG1414	Transcriptional regulator
G3H79_RS09975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G3H79_RS09980	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3H79_RS09985	COG5002	protein histidine kinase activity
G3H79_RS09990	COG2018	Roadblock/LC7 domain
G3H79_RS10010	COG2018	Roadblock/LC7 domain
G3H79_RS10030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3H79_RS10065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3H79_RS10095	COG2957	Belongs to the agmatine deiminase family
G3H79_RS10100	COG0804	urea catabolic process
G3H79_RS10105	COG0832	Belongs to the urease beta subunit family
G3H79_RS10105	COG0831	urea catabolic process
G3H79_RS10120	COG1309	transcriptional regulator
G3H79_RS10125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3H79_RS10130	COG0473	3-isopropylmalate dehydrogenase activity
G3H79_RS10140	COG0583	DNA-binding transcription factor activity
G3H79_RS10145	COG2130	NADP-dependent
G3H79_RS10160	COG0575	Belongs to the CDS family
G3H79_RS10175	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS10180	COG0506	proline dehydrogenase activity
G3H79_RS10195	COG0477	Major facilitator Superfamily
G3H79_RS10200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3H79_RS10205	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G3H79_RS10210	COG0440	acetolactate synthase activity
G3H79_RS10235	COG0667	Aldo Keto reductase
G3H79_RS10240	COG2133	pyrroloquinoline quinone binding
G3H79_RS10250	COG1672	PFAM Archaeal ATPase
G3H79_RS10250	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G3H79_RS10270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3H79_RS10275	COG2409	Drug exporters of the RND superfamily
G3H79_RS10285	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G3H79_RS10295	COG0154	amidase activity
G3H79_RS10300	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G3H79_RS10305	COG5650	phosphatidylinositol metabolic process
G3H79_RS10315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G3H79_RS10325	COG4221	oxidoreductase activity
G3H79_RS10340	COG4977	sequence-specific DNA binding
G3H79_RS10360	COG0482	sulfurtransferase activity
G3H79_RS10390	COG2378	regulation of single-species biofilm formation
G3H79_RS10395	COG0583	DNA-binding transcription factor activity
G3H79_RS10405	COG2855	membrane
G3H79_RS10415	COG2860	membrane
G3H79_RS10420	COG4608	Belongs to the ABC transporter superfamily
G3H79_RS10425	COG0444	Belongs to the ABC transporter superfamily
G3H79_RS10430	COG0601	transmembrane transport
G3H79_RS10440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3H79_RS10460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G3H79_RS10465	COG0509	glycine decarboxylation via glycine cleavage system
G3H79_RS10470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3H79_RS10475	COG1760	l-serine dehydratase
G3H79_RS10480	COG0823	Involved in the tonB-independent uptake of proteins
G3H79_RS10490	COG0604	alcohol dehydrogenase
G3H79_RS10500	COG2367	Beta-lactamase
G3H79_RS10540	COG1376	ErfK ybiS ycfS ynhG family protein
G3H79_RS10560	COG1132	(ABC) transporter
G3H79_RS10565	COG1132	(ABC) transporter
G3H79_RS10580	COG0058	SHG alpha-glucan phosphorylase activity
G3H79_RS10600	COG0366	Alpha amylase catalytic
G3H79_RS10610	COG3281	Trehalose synthase
G3H79_RS10615	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G3H79_RS10630	COG0789	Transcriptional regulator
G3H79_RS10640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3H79_RS10645	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G3H79_RS10655	COG2409	Drug exporters of the RND superfamily
G3H79_RS10690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3H79_RS10715	COG0477	Major facilitator Superfamily
G3H79_RS10775	COG1301	dicarboxylic acid transport
G3H79_RS10780	COG3290	protein histidine kinase activity
G3H79_RS10785	COG4565	transcriptional regulatory protein
G3H79_RS10800	COG0395	ABC-type sugar transport system, permease component
G3H79_RS10810	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G3H79_RS10825	COG0205	6-phosphofructokinase activity
G3H79_RS10830	COG0857	belongs to the CobB CobQ family
G3H79_RS10830	COG0280	phosphate acetyltransferase
G3H79_RS10835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G3H79_RS10870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3H79_RS10875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G3H79_RS10880	COG0745	RESPONSE REGULATOR receiver
G3H79_RS10895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3H79_RS10895	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3H79_RS10940	COG1309	transcriptional regulator
G3H79_RS10990	COG0745	RESPONSE REGULATOR receiver
G3H79_RS11005	COG0183	Belongs to the thiolase family
G3H79_RS11060	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
G3H79_RS11075	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3H79_RS11105	COG4585	Histidine kinase
G3H79_RS11110	COG2197	response regulator
G3H79_RS11120	COG2409	Drug exporters of the RND superfamily
G3H79_RS11125	COG4585	Histidine kinase
G3H79_RS11130	COG2197	response regulator
G3H79_RS11140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G3H79_RS11145	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G3H79_RS11150	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G3H79_RS11155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G3H79_RS11160	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G3H79_RS11165	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G3H79_RS11170	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G3H79_RS11190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3H79_RS11195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3H79_RS11205	COG2890	protein-(glutamine-N5) methyltransferase activity
G3H79_RS11210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G3H79_RS11215	COG0254	rRNA binding
G3H79_RS11230	COG0083	homoserine kinase activity
G3H79_RS11235	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G3H79_RS11240	COG0460	homoserine dehydrogenase
G3H79_RS11245	COG0019	diaminopimelate decarboxylase activity
G3H79_RS11250	COG0018	arginyl-trna synthetase
G3H79_RS11280	COG2267	carboxylic ester hydrolase activity
G3H79_RS11285	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G3H79_RS11290	COG3285	dna ligase
G3H79_RS11290	COG1793	dna ligase
G3H79_RS11315	COG2205	protein histidine kinase activity
G3H79_RS11330	COG0768	penicillin binding
G3H79_RS11335	COG2318	DinB family
G3H79_RS11410	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3H79_RS11440	COG0745	RESPONSE REGULATOR receiver
G3H79_RS11445	COG2205	protein histidine kinase activity
G3H79_RS11450	COG0567	Dehydrogenase, E1 component
G3H79_RS11450	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3H79_RS11500	COG0604	alcohol dehydrogenase
G3H79_RS11520	COG1126	abc transporter atp-binding protein
G3H79_RS11525	COG4106	trans-aconitate 2-methyltransferase activity
G3H79_RS11550	COG1595	DNA-templated transcription, initiation
G3H79_RS11585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3H79_RS11600	COG2515	1-aminocyclopropane-1-carboxylate deaminase
G3H79_RS11615	COG2172	sigma factor antagonist activity
G3H79_RS11630	COG1597	lipid kinase activity
G3H79_RS11645	COG1309	transcriptional regulator
G3H79_RS11650	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS11655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G3H79_RS11660	COG0363	glucosamine-6-phosphate deaminase activity
G3H79_RS11665	COG1472	Belongs to the glycosyl hydrolase 3 family
G3H79_RS11670	COG0395	ABC-type sugar transport system, permease component
G3H79_RS11675	COG1175	transmembrane transport
G3H79_RS11680	COG2182	Extracellular solute-binding protein
G3H79_RS11685	COG2188	Transcriptional regulator
G3H79_RS11690	COG1966	Carbon starvation protein
G3H79_RS11725	COG4977	sequence-specific DNA binding
G3H79_RS11730	COG2124	cytochrome p450
G3H79_RS11740	COG0242	peptide deformylase activity
G3H79_RS11760	COG5662	AntiSigma factor
G3H79_RS11765	COG1595	DNA-templated transcription, initiation
G3H79_RS11775	COG2135	peptidase activity
G3H79_RS11785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G3H79_RS11790	COG1162	GTPase activity
G3H79_RS11795	COG2076	Multidrug Resistance protein
G3H79_RS11805	COG0483	inositol monophosphate 1-phosphatase activity
G3H79_RS11815	COG0753	catalase activity
G3H79_RS11840	COG1615	UPF0182 protein
G3H79_RS11850	COG3480	Lon protease (S16) C-terminal proteolytic domain
G3H79_RS11905	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G3H79_RS11945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3H79_RS11975	COG0596	Alpha beta hydrolase
G3H79_RS12015	COG0601	transmembrane transport
G3H79_RS12025	COG0747	negative chemotaxis
G3H79_RS12065	COG0513	Belongs to the DEAD box helicase family
G3H79_RS12070	COG0596	Alpha beta hydrolase
G3H79_RS12075	COG1432	Conserved Protein
G3H79_RS12080	COG2095	MarC family integral membrane protein
G3H79_RS12095	COG2814	Major facilitator Superfamily
G3H79_RS12105	COG0598	Magnesium transport protein CorA
G3H79_RS12140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3H79_RS12145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3H79_RS12160	COG1595	DNA-templated transcription, initiation
G3H79_RS12175	COG1024	Enoyl-CoA hydratase
G3H79_RS12180	COG2818	Glycosylase
G3H79_RS12190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G3H79_RS12195	COG1611	Belongs to the LOG family
G3H79_RS12200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3H79_RS12240	COG2197	response regulator
G3H79_RS12245	COG4585	Histidine kinase
G3H79_RS12255	COG1131	(ABC) transporter
G3H79_RS12270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G3H79_RS12285	COG4608	Belongs to the ABC transporter superfamily
G3H79_RS12290	COG0444	Belongs to the ABC transporter superfamily
G3H79_RS12295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3H79_RS12300	COG0601	transmembrane transport
G3H79_RS12320	COG4608	Belongs to the ABC transporter superfamily
G3H79_RS12325	COG0444	Belongs to the ABC transporter superfamily
G3H79_RS12330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3H79_RS12335	COG0601	transmembrane transport
G3H79_RS12370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3H79_RS12385	COG1842	Phage shock protein A
G3H79_RS12430	COG1846	Transcriptional regulator
G3H79_RS12435	COG0778	Nitroreductase
G3H79_RS12450	COG0582	viral genome integration into host DNA
G3H79_RS12490	COG0012	GTP binding
G3H79_RS12505	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G3H79_RS12515	COG1570	exodeoxyribonuclease VII activity
G3H79_RS12520	COG1722	exodeoxyribonuclease VII activity
G3H79_RS12525	COG0778	Nitroreductase
G3H79_RS12550	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
G3H79_RS12550	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
G3H79_RS12560	COG0114	fumarate hydratase activity
G3H79_RS12585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3H79_RS12595	COG1136	(ABC) transporter
G3H79_RS12610	COG0450	alkyl hydroperoxide reductase
G3H79_RS12615	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3H79_RS12630	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G3H79_RS12635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G3H79_RS12640	COG0667	Aldo Keto reductase
G3H79_RS12645	COG1733	regulation of RNA biosynthetic process
G3H79_RS12660	COG4555	ABC transporter
G3H79_RS12680	COG2885	chlorophyll binding
G3H79_RS12715	COG2894	cell division
G3H79_RS12815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3H79_RS12870	COG2610	gluconate transmembrane transporter activity
G3H79_RS12875	COG0251	oxidation-reduction process
G3H79_RS12880	COG1414	Transcriptional regulator
G3H79_RS12895	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3H79_RS12915	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G3H79_RS12925	COG0477	Major facilitator Superfamily
G3H79_RS12930	COG1309	transcriptional regulator
G3H79_RS12940	COG1331	Highly conserved protein containing a thioredoxin domain
G3H79_RS12970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G3H79_RS12980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3H79_RS13010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3H79_RS13015	COG2255	four-way junction helicase activity
G3H79_RS13020	COG1595	DNA-templated transcription, initiation
G3H79_RS13040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3H79_RS13055	COG1064	alcohol dehydrogenase
G3H79_RS13070	COG1733	regulation of RNA biosynthetic process
G3H79_RS13080	COG1404	Belongs to the peptidase S8 family
G3H79_RS13125	COG1940	carbohydrate kinase activity
G3H79_RS13130	COG0531	amino acid
G3H79_RS13135	COG2986	histidine ammonia-lyase
G3H79_RS13145	COG1024	Enoyl-CoA hydratase
G3H79_RS13150	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G3H79_RS13160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3H79_RS13170	COG0424	maF-like protein
G3H79_RS13180	COG4770	biotin carboxylase activity
G3H79_RS13210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3H79_RS13225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3H79_RS13255	COG0581	inorganic phosphate transmembrane transporter activity
G3H79_RS13280	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G3H79_RS13285	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS13290	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS13295	COG4585	Histidine kinase
G3H79_RS13300	COG2197	response regulator
G3H79_RS13315	COG1595	DNA-templated transcription, initiation
G3H79_RS13320	COG0745	RESPONSE REGULATOR receiver
G3H79_RS13325	COG2205	protein histidine kinase activity
G3H79_RS13350	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3H79_RS13360	COG1132	(ABC) transporter
G3H79_RS13395	COG2814	Major facilitator Superfamily
G3H79_RS13400	COG0583	DNA-binding transcription factor activity
G3H79_RS13450	COG1744	ABC transporter substrate-binding protein PnrA-like
G3H79_RS13455	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G3H79_RS13455	COG1473	amidohydrolase
G3H79_RS13465	COG0438	transferase activity, transferring glycosyl groups
G3H79_RS13490	COG2089	acid synthase
G3H79_RS13505	COG1216	Glycosyl transferase, family 2
G3H79_RS13545	COG1595	DNA-templated transcription, initiation
G3H79_RS13575	COG3525	Glycosyl hydrolase, family 20, catalytic domain
G3H79_RS13585	COG2009	succinate dehydrogenase
G3H79_RS13595	COG1053	succinate dehydrogenase
G3H79_RS13620	COG1140	nitrate reductase beta subunit
G3H79_RS13665	COG1595	DNA-templated transcription, initiation
G3H79_RS13680	COG0745	RESPONSE REGULATOR receiver
G3H79_RS13685	COG2205	protein histidine kinase activity
G3H79_RS13690	COG1408	metallophosphoesterase
G3H79_RS13715	COG0671	phosphoesterase, PA-phosphatase related
G3H79_RS13740	COG0180	Tryptophanyl-tRNA synthetase
G3H79_RS13750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3H79_RS13755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3H79_RS13765	COG2130	NADP-dependent
G3H79_RS13770	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3H79_RS13845	COG0754	glutathionylspermidine amidase activity
G3H79_RS13860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3H79_RS13865	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3H79_RS13870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3H79_RS13880	COG0688	phosphatidylethanolamine metabolic process
G3H79_RS13895	COG4176	ABC-type proline glycine betaine transport system permease component
G3H79_RS13900	COG4175	Glycine betaine
G3H79_RS13900	COG0517	IMP dehydrogenase activity
G3H79_RS13910	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS13925	COG1476	TRANSCRIPTIONal
G3H79_RS13935	COG0477	Major facilitator Superfamily
G3H79_RS13955	COG0039	L-malate dehydrogenase activity
G3H79_RS13975	COG2197	response regulator
G3H79_RS13980	COG4585	Histidine kinase
G3H79_RS13990	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G3H79_RS14000	COG0138	bifunctional purine biosynthesis protein purh
G3H79_RS14035	COG0045	succinate-CoA ligase (ADP-forming) activity
G3H79_RS14050	COG3552	Protein containing von Willebrand factor type A (VWA) domain
G3H79_RS14055	COG2425	protein containing a von Willebrand factor type A (vWA) domain
G3H79_RS14060	COG0714	Associated with various cellular activities
G3H79_RS14075	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3H79_RS14075	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G3H79_RS14110	COG2197	response regulator
G3H79_RS14150	COG0519	Catalyzes the synthesis of GMP from XMP
G3H79_RS14150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G3H79_RS14180	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS14185	COG0515	serine threonine protein kinase
G3H79_RS14190	COG0515	serine threonine protein kinase
G3H79_RS14195	COG0515	serine threonine protein kinase
G3H79_RS14210	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G3H79_RS14225	COG0516	GMP reductase activity
G3H79_RS14235	COG1595	DNA-templated transcription, initiation
G3H79_RS14240	COG2197	response regulator
G3H79_RS14250	COG0583	DNA-binding transcription factor activity
G3H79_RS14260	COG4221	oxidoreductase activity
G3H79_RS14265	COG0459	protein refolding
G3H79_RS14280	COG0726	polysaccharide deacetylase
G3H79_RS14290	COG4941	Belongs to the sigma-70 factor family
G3H79_RS14320	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G3H79_RS14325	COG0456	acetyltransferase
G3H79_RS14330	COG0456	acetyltransferase
G3H79_RS14330	COG1214	PFAM Peptidase M22, glycoprotease
G3H79_RS14345	COG0802	atpase or kinase
G3H79_RS14355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G3H79_RS14365	COG0736	holo-[acyl-carrier-protein] synthase activity
G3H79_RS14370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G3H79_RS14375	COG1072	(Pantothenic acid kinase))
G3H79_RS14385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3H79_RS14390	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G3H79_RS14395	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G3H79_RS14410	COG0101	tRNA pseudouridine synthase activity
G3H79_RS14415	COG0203	ribosomal protein L17
G3H79_RS14420	COG0202	RNA polymerase activity
G3H79_RS14425	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G3H79_RS14430	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G3H79_RS14435	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G3H79_RS14440	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G3H79_RS14450	COG0563	adenylate kinase activity
G3H79_RS14460	COG0200	Binds to the 23S rRNA
G3H79_RS14465	COG1841	ribosomal large subunit assembly
G3H79_RS14470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G3H79_RS14475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G3H79_RS14480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G3H79_RS14485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G3H79_RS14495	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G3H79_RS14500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G3H79_RS14505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G3H79_RS14510	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G3H79_RS14515	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G3H79_RS14520	COG0255	Belongs to the universal ribosomal protein uL29 family
G3H79_RS14525	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G3H79_RS14530	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G3H79_RS14535	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G3H79_RS14540	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G3H79_RS14545	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G3H79_RS14550	COG0089	rRNA binding
G3H79_RS14555	COG0088	Forms part of the polypeptide exit tunnel
G3H79_RS14560	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G3H79_RS14565	COG0051	transcription antitermination factor activity, RNA binding
G3H79_RS14570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3H79_RS14575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G3H79_RS14580	COG0049	tRNA binding
G3H79_RS14585	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G3H79_RS14595	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G3H79_RS14600	COG0085	RNA polymerase activity
G3H79_RS14605	COG0222	ribosome binding
G3H79_RS14610	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G3H79_RS14625	COG0081	regulation of translation
G3H79_RS14630	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G3H79_RS14640	COG0250	Participates in transcription elongation, termination and antitermination
G3H79_RS14655	COG0436	Aminotransferase
G3H79_RS14660	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3H79_RS14665	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G3H79_RS14670	COG0477	Major facilitator Superfamily
G3H79_RS14685	COG2030	dehydratase
G3H79_RS14690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G3H79_RS14710	COG0702	epimerase
G3H79_RS14725	COG1666	GTP binding
G3H79_RS14730	COG2261	transglycosylase associated protein
G3H79_RS14740	COG3304	Inner membrane component domain
G3H79_RS14745	COG0501	Belongs to the peptidase M48B family
G3H79_RS14750	COG1007	ATP synthesis coupled electron transport
G3H79_RS14760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G3H79_RS14765	COG0713	ATP synthesis coupled electron transport
G3H79_RS14775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3H79_RS14780	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G3H79_RS14785	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3H79_RS14790	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3H79_RS14795	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3H79_RS14815	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G3H79_RS14815	COG0674	pyruvate-flavodoxin oxidoreductase activity
G3H79_RS14820	COG1013	pyruvate-flavodoxin oxidoreductase activity
G3H79_RS14825	COG1733	regulation of RNA biosynthetic process
G3H79_RS14830	COG0702	epimerase
G3H79_RS14855	COG1733	regulation of RNA biosynthetic process
G3H79_RS14865	COG0662	Cupin 2, conserved barrel domain protein
G3H79_RS14880	COG3903	Transcriptional regulator
G3H79_RS14880	COG3629	intracellular signal transduction
G3H79_RS14930	COG0561	phosphatase activity
G3H79_RS14965	COG1007	ATP synthesis coupled electron transport
G3H79_RS14975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G3H79_RS14980	COG0713	ATP synthesis coupled electron transport
G3H79_RS14985	COG0839	Belongs to the complex I subunit 6 family
G3H79_RS14990	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3H79_RS14995	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G3H79_RS15000	COG1034	ATP synthesis coupled electron transport
G3H79_RS15005	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G3H79_RS15015	COG0649	NAD binding
G3H79_RS15020	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3H79_RS15025	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G3H79_RS15035	COG0791	NLP P60 protein
G3H79_RS15035	COG1388	LysM domain
G3H79_RS15035	COG3103	Sh3 type 3 domain protein
G3H79_RS15060	COG2226	methyltransferase
G3H79_RS15070	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G3H79_RS15115	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
G3H79_RS15130	COG5640	endopeptidase activity
G3H79_RS15135	COG1660	Displays ATPase and GTPase activities
G3H79_RS15205	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
G3H79_RS15215	COG4608	Belongs to the ABC transporter superfamily
G3H79_RS15230	COG0601	transmembrane transport
G3H79_RS15235	COG0747	negative chemotaxis
G3H79_RS15260	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3H79_RS15315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G3H79_RS15415	COG1301	dicarboxylic acid transport
G3H79_RS15425	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G3H79_RS15435	COG0163	prenyltransferase activity
G3H79_RS15440	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3H79_RS15445	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G3H79_RS15475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G3H79_RS15480	COG1333	cytochrome c biogenesis protein
G3H79_RS15490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3H79_RS15500	COG0406	alpha-ribazole phosphatase activity
G3H79_RS15505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G3H79_RS15515	COG0768	penicillin binding
G3H79_RS15525	COG0583	DNA-binding transcription factor activity
G3H79_RS15555	COG1742	UPF0060 membrane protein
G3H79_RS15575	COG1690	Belongs to the RtcB family
G3H79_RS15605	COG2814	Major facilitator Superfamily
G3H79_RS15640	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
G3H79_RS15645	COG0018	arginyl-trna synthetase
G3H79_RS15650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3H79_RS15680	COG0113	porphobilinogen synthase activity
G3H79_RS15685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G3H79_RS15685	COG1648	precorrin-2 dehydrogenase activity
G3H79_RS15690	COG0181	hydroxymethylbilane synthase activity
G3H79_RS15695	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G3H79_RS15700	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
G3H79_RS15750	COG0123	including yeast histone deacetylase and acetoin utilization protein
G3H79_RS15755	COG2223	nitrite transmembrane transporter activity
G3H79_RS15760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3H79_RS15780	COG0180	Tryptophanyl-tRNA synthetase
G3H79_RS15785	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G3H79_RS15795	COG1129	ABC transporter
G3H79_RS15795	COG0842	Transport permease protein
G3H79_RS15815	COG4991	sh3 domain protein
G3H79_RS15820	COG0129	dihydroxy-acid dehydratase activity
G3H79_RS15830	COG1082	Xylose isomerase domain protein TIM barrel
G3H79_RS15835	COG0248	Ppx GppA phosphatase
G3H79_RS15855	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
G3H79_RS15865	COG0671	phosphoesterase, PA-phosphatase related
G3H79_RS15875	COG4585	Histidine kinase
G3H79_RS15880	COG1194	a g-specific adenine glycosylase
G3H79_RS15885	COG1595	DNA-templated transcription, initiation
G3H79_RS15895	COG0745	RESPONSE REGULATOR receiver
G3H79_RS15900	COG2205	protein histidine kinase activity
G3H79_RS15905	COG0346	lactoylglutathione lyase activity
G3H79_RS15915	COG0477	Major facilitator Superfamily
G3H79_RS15925	COG0739	heme binding
G3H79_RS15965	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G3H79_RS15990	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G3H79_RS16000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G3H79_RS16010	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G3H79_RS16020	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
G3H79_RS16030	COG2197	response regulator
G3H79_RS16045	COG0649	NAD binding
G3H79_RS16070	COG1174	glycine betaine transport
G3H79_RS16075	COG1174	glycine betaine transport
G3H79_RS16090	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G3H79_RS16090	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G3H79_RS16110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G3H79_RS16125	COG0302	gtp cyclohydrolase
G3H79_RS16140	COG0037	tRNA processing
G3H79_RS16150	COG2027	D-alanyl-D-alanine carboxypeptidase
G3H79_RS16155	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G3H79_RS16170	COG0789	Transcriptional regulator
G3H79_RS16175	COG0076	glutamate decarboxylase activity
G3H79_RS16195	COG2318	DinB family
G3H79_RS16200	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS16220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G3H79_RS16230	COG0254	rRNA binding
G3H79_RS16235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G3H79_RS16240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G3H79_RS16245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G3H79_RS16275	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G3H79_RS16275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3H79_RS16290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3H79_RS16290	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3H79_RS16295	COG3629	intracellular signal transduction
G3H79_RS16295	COG3903	Transcriptional regulator
G3H79_RS16305	COG0431	NADPH-dependent FMN reductase
G3H79_RS16315	COG5002	protein histidine kinase activity
G3H79_RS16320	COG0745	RESPONSE REGULATOR receiver
G3H79_RS16345	COG0596	Alpha beta hydrolase
G3H79_RS16360	COG2197	response regulator
G3H79_RS16410	COG1595	DNA-templated transcription, initiation
G3H79_RS16420	COG0596	Alpha beta hydrolase
G3H79_RS16440	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS16465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G3H79_RS16470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G3H79_RS16475	COG1754	DNA topoisomerase type I activity
G3H79_RS16475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3H79_RS16485	COG2890	protein-(glutamine-N5) methyltransferase activity
G3H79_RS16495	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G3H79_RS16500	COG2172	sigma factor antagonist activity
G3H79_RS16505	COG1366	Belongs to the anti-sigma-factor antagonist family
G3H79_RS16510	COG1111	helicase
G3H79_RS16510	COG1205	dead DEAH box helicase
G3H79_RS16570	COG0659	secondary active sulfate transmembrane transporter activity
G3H79_RS16575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3H79_RS16580	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G3H79_RS16590	COG0596	Alpha beta hydrolase
G3H79_RS16625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3H79_RS16650	COG0003	Pfam Anion-transporting ATPase
G3H79_RS16665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3H79_RS16675	COG1408	metallophosphoesterase
G3H79_RS16705	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G3H79_RS16710	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G3H79_RS16720	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G3H79_RS16775	COG4249	Peptidase C14 caspase catalytic subunit p20
G3H79_RS16775	COG2319	Wd-40 repeat
G3H79_RS16840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3H79_RS16865	COG1595	DNA-templated transcription, initiation
G3H79_RS16905	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G3H79_RS16910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G3H79_RS16925	COG0463	Glycosyl transferase, family 2
G3H79_RS16965	COG0693	protein deglycase activity
G3H79_RS16975	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3H79_RS16975	COG0515	serine threonine protein kinase
G3H79_RS16980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G3H79_RS16985	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G3H79_RS17005	COG2124	cytochrome p450
G3H79_RS17010	COG2197	response regulator
G3H79_RS17015	COG4585	Histidine kinase
G3H79_RS17025	COG3844	kynureninase activity
G3H79_RS17040	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G3H79_RS17045	COG0191	fructose-bisphosphate aldolase activity
G3H79_RS17050	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G3H79_RS17065	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G3H79_RS17095	COG0542	response to heat
G3H79_RS17150	COG0789	Transcriptional regulator
G3H79_RS17155	COG0484	heat shock protein binding
G3H79_RS17160	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G3H79_RS17165	COG0443	Heat shock 70 kDa protein
G3H79_RS17170	COG0247	lactate metabolic process
G3H79_RS17170	COG2181	nitrate reductase activity
G3H79_RS17235	COG0717	Belongs to the dCTP deaminase family
G3H79_RS17245	COG1609	Transcriptional regulator
G3H79_RS17275	COG1434	Gram-negative-bacterium-type cell wall biogenesis
G3H79_RS17310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3H79_RS17345	COG2319	Wd-40 repeat
G3H79_RS17345	COG4249	Peptidase C14 caspase catalytic subunit p20
G3H79_RS17355	COG3835	regulator
G3H79_RS17370	COG1278	Cold shock
G3H79_RS17375	COG0513	Belongs to the DEAD box helicase family
G3H79_RS17485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS17490	COG1733	regulation of RNA biosynthetic process
G3H79_RS17495	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G3H79_RS17505	COG3655	Transcriptional regulator
G3H79_RS17540	COG0477	Major facilitator Superfamily
G3H79_RS17565	COG0583	DNA-binding transcription factor activity
G3H79_RS17620	COG1289	transmembrane transporter activity
G3H79_RS17630	COG0583	DNA-binding transcription factor activity
G3H79_RS17655	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3H79_RS17660	COG1309	transcriptional regulator
G3H79_RS17720	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G3H79_RS17735	COG1741	Belongs to the pirin family
G3H79_RS17750	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS17755	COG1362	aminopeptidase activity
G3H79_RS17780	COG2186	Transcriptional regulator
G3H79_RS17790	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3H79_RS17795	COG0022	dehydrogenase e1 component
G3H79_RS17815	COG0515	serine threonine protein kinase
G3H79_RS17820	COG0515	serine threonine protein kinase
G3H79_RS17825	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3H79_RS17845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G3H79_RS17875	COG1522	sequence-specific DNA binding
G3H79_RS17880	COG1309	transcriptional regulator
G3H79_RS17885	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3H79_RS17910	COG3396	Phenylacetate-CoA oxygenase
G3H79_RS17915	COG3460	Phenylacetate-CoA oxygenase
G3H79_RS17920	COG3396	Phenylacetate-CoA oxygenase
G3H79_RS17925	COG2151	metal-sulfur cluster biosynthetic enzyme
G3H79_RS17930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3H79_RS17960	COG1716	ATPase activity
G3H79_RS17965	COG1716	ATPase activity
G3H79_RS17980	COG0768	penicillin binding
G3H79_RS17985	COG0515	serine threonine protein kinase
G3H79_RS17990	COG3764	Sortase (surface protein transpeptidase)
G3H79_RS17995	COG3764	Sortase (surface protein transpeptidase)
G3H79_RS18005	COG3764	Sortase (surface protein transpeptidase)
G3H79_RS18020	COG0457	Tetratricopeptide repeat
G3H79_RS18020	COG0705	Rhomboid family
G3H79_RS18050	COG2201	protein-glutamate methylesterase activity
G3H79_RS18115	COG0297	glycogen (starch) synthase activity
G3H79_RS18120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3H79_RS18140	COG0438	transferase activity, transferring glycosyl groups
G3H79_RS18215	COG0515	serine threonine protein kinase
G3H79_RS18245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G3H79_RS18255	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
G3H79_RS18260	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G3H79_RS18265	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G3H79_RS18270	COG0592	DNA-directed DNA polymerase activity
G3H79_RS18275	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G3H79_RS18280	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G3H79_RS18285	COG0594	ribonuclease P activity
G3H79_RS18290	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G3H79_RS18295	COG0706	membrane insertase activity
G3H79_RS18305	COG0357	Ribosomal RNA small subunit methyltransferase G
G3H79_RS18310	COG1192	Involved in chromosome partitioning
G3H79_RS18325	COG3118	belongs to the thioredoxin family
G3H79_RS18330	COG0492	ferredoxin-NADP+ reductase activity
G3H79_RS18340	COG1595	DNA-templated transcription, initiation
G3H79_RS18360	COG0617	tRNA 3'-terminal CCA addition
G3H79_RS18375	COG1260	myo-inositol-1-phosphate synthase
G3H79_RS18385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3H79_RS18410	COG0360	Binds together with S18 to 16S ribosomal RNA
G3H79_RS18415	COG0629	single-stranded DNA binding
G3H79_RS18420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G3H79_RS18425	COG0359	binds to the 23S rRNA
G3H79_RS18430	COG0534	Mate efflux family protein
G3H79_RS18435	COG0305	Participates in initiation and elongation during chromosome replication
G3H79_RS18465	COG2814	Major facilitator Superfamily
G3H79_RS18505	COG0626	cystathionine gamma-synthase activity
G3H79_RS18510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3H79_RS18515	COG1950	PFAM Membrane protein of
G3H79_RS18520	COG0662	Cupin 2, conserved barrel domain protein
G3H79_RS18545	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G3H79_RS18565	COG1609	Transcriptional regulator
G3H79_RS18570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3H79_RS18575	COG1271	oxidase subunit
G3H79_RS18580	COG1294	oxidase, subunit
G3H79_RS18585	COG4988	ABC transporter
G3H79_RS18595	COG0741	lytic transglycosylase activity
G3H79_RS18595	COG1196	nuclear chromosome segregation
G3H79_RS18595	COG0739	heme binding
G3H79_RS18600	COG0561	phosphatase activity
G3H79_RS18615	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
G3H79_RS18620	COG0789	Transcriptional regulator
G3H79_RS18665	COG0561	phosphatase activity
G3H79_RS18670	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G3H79_RS18680	COG2837	iron assimilation
G3H79_RS18695	COG1999	signal sequence binding
G3H79_RS18720	COG1733	regulation of RNA biosynthetic process
G3H79_RS18725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3H79_RS18730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3H79_RS18735	COG0006	proline dipeptidase activity
G3H79_RS18755	COG0653	protein targeting
G3H79_RS18770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3H79_RS18790	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS18820	COG1595	DNA-templated transcription, initiation
G3H79_RS18825	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS18830	COG2814	Major facilitator Superfamily
G3H79_RS18835	COG1309	transcriptional regulator
G3H79_RS18840	COG0784	Response regulator, receiver
G3H79_RS18870	COG1595	DNA-templated transcription, initiation
G3H79_RS18905	COG0745	RESPONSE REGULATOR receiver
G3H79_RS18910	COG2205	protein histidine kinase activity
G3H79_RS18920	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3H79_RS18925	COG0477	Major facilitator Superfamily
G3H79_RS18935	COG3467	pyridoxamine 5'-phosphate
G3H79_RS18945	COG0477	Major facilitator Superfamily
G3H79_RS18965	COG1191	sigma factor activity
G3H79_RS18970	COG1191	sigma factor activity
G3H79_RS19000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G3H79_RS19015	COG0433	COG0433 Predicted ATPase
G3H79_RS19025	COG0488	(ABC) transporter
G3H79_RS19040	COG0583	DNA-binding transcription factor activity
G3H79_RS19045	COG0697	spore germination
G3H79_RS19055	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS19065	COG0640	Transcriptional regulator
G3H79_RS19075	COG1309	transcriptional regulator
G3H79_RS19210	COG0151	Belongs to the GarS family
G3H79_RS19225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G3H79_RS19235	COG2197	response regulator
G3H79_RS19270	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G3H79_RS19275	COG0047	phosphoribosylformylglycinamidine synthase activity
G3H79_RS19280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G3H79_RS19315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G3H79_RS19350	COG1643	Atp-dependent helicase
G3H79_RS19360	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G3H79_RS19360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3H79_RS19365	COG0785	Cytochrome C biogenesis protein
G3H79_RS19400	COG0513	Belongs to the DEAD box helicase family
G3H79_RS19440	COG1917	Cupin 2, conserved barrel domain protein
G3H79_RS19475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G3H79_RS19495	COG0667	Aldo Keto reductase
G3H79_RS19505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G3H79_RS19510	COG0579	oxidoreductase
G3H79_RS19540	COG1252	NADH dehydrogenase
G3H79_RS19575	COG2197	response regulator
G3H79_RS19580	COG4585	Histidine kinase
G3H79_RS19590	COG1131	(ABC) transporter
G3H79_RS19635	COG0456	acetyltransferase
G3H79_RS19650	COG1122	ATPase activity
G3H79_RS19665	COG0741	lytic transglycosylase activity
G3H79_RS19665	COG1196	nuclear chromosome segregation
G3H79_RS19665	COG0739	heme binding
G3H79_RS19670	COG0671	phosphoesterase, PA-phosphatase related
G3H79_RS19675	COG0277	FAD linked oxidase domain protein
G3H79_RS19690	COG1937	Protein conserved in bacteria
G3H79_RS19700	COG0306	phosphate transporter
G3H79_RS19710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3H79_RS19740	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G3H79_RS19760	COG0456	acetyltransferase
G3H79_RS19765	COG0737	Belongs to the 5'-nucleotidase family
G3H79_RS19785	COG0745	RESPONSE REGULATOR receiver
G3H79_RS19790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3H79_RS19795	COG1609	Transcriptional regulator
G3H79_RS19800	COG0745	RESPONSE REGULATOR receiver
G3H79_RS19825	COG2897	thiosulfate sulfurtransferase activity
G3H79_RS19840	COG3485	protocatechuate 3,4-dioxygenase
G3H79_RS19850	COG0354	folic acid binding
G3H79_RS19855	COG1490	D-aminoacyl-tRNA deacylase activity
G3H79_RS19875	COG2188	Transcriptional regulator
G3H79_RS19930	COG0210	DNA helicase
G3H79_RS19970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3H79_RS19980	COG1595	DNA-templated transcription, initiation
G3H79_RS20020	COG0438	transferase activity, transferring glycosyl groups
G3H79_RS20050	COG0588	phosphoglycerate mutase activity
G3H79_RS20060	COG5002	protein histidine kinase activity
G3H79_RS20080	COG1329	Transcriptional regulator
G3H79_RS20085	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G3H79_RS20090	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G3H79_RS20095	COG3467	pyridoxamine 5'-phosphate
G3H79_RS20100	COG0215	cysteine-tRNA ligase activity
G3H79_RS20105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3H79_RS20115	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G3H79_RS20125	COG3842	ATPase activity
G3H79_RS20135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3H79_RS20160	COG4552	Acetyltransferase involved in intracellular survival and related
G3H79_RS20180	COG2197	response regulator
G3H79_RS20220	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G3H79_RS20245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G3H79_RS20275	COG0463	Glycosyl transferase, family 2
G3H79_RS20280	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G3H79_RS20295	COG0459	protein refolding
G3H79_RS20335	COG1595	DNA-templated transcription, initiation
G3H79_RS20345	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G3H79_RS20350	COG1737	Transcriptional regulator
G3H79_RS20400	COG3973	AAA domain
G3H79_RS20410	COG1061	Type III restriction enzyme res subunit
G3H79_RS20435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3H79_RS20440	COG1120	ATPase activity
G3H79_RS20445	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3H79_RS20450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3H79_RS20465	COG1278	Cold shock
G3H79_RS20470	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
G3H79_RS20475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G3H79_RS20485	COG2814	Major facilitator Superfamily
G3H79_RS20510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G3H79_RS20520	COG2252	PERMEase
G3H79_RS20555	COG0667	Aldo Keto reductase
G3H79_RS20640	COG1090	epimerase
G3H79_RS20660	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G3H79_RS20665	COG2318	DinB family
G3H79_RS20670	COG0277	FAD linked oxidase domain protein
G3H79_RS20670	COG0247	lactate metabolic process
G3H79_RS20695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3H79_RS20740	COG0259	pyridoxamine-phosphate oxidase activity
G3H79_RS20745	COG0596	Alpha beta hydrolase
G3H79_RS20745	COG2945	thiolester hydrolase activity
G3H79_RS20755	COG4821	SIS domain
G3H79_RS20760	COG2205	protein histidine kinase activity
G3H79_RS20765	COG0745	RESPONSE REGULATOR receiver
G3H79_RS20780	COG1136	(ABC) transporter
G3H79_RS20780	COG0577	efflux transmembrane transporter activity
G3H79_RS20785	COG1136	(ABC) transporter
G3H79_RS20785	COG0577	efflux transmembrane transporter activity
G3H79_RS20815	COG1131	(ABC) transporter
G3H79_RS20860	COG1366	Belongs to the anti-sigma-factor antagonist family
G3H79_RS20870	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS20875	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS20880	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS20900	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS20925	COG2814	Major facilitator Superfamily
G3H79_RS20930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3H79_RS20935	COG1024	Enoyl-CoA hydratase
G3H79_RS20945	COG2072	flavoprotein involved in K transport
G3H79_RS20985	COG1309	transcriptional regulator
G3H79_RS20995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3H79_RS20995	COG0515	serine threonine protein kinase
G3H79_RS21000	COG1024	Enoyl-CoA hydratase
G3H79_RS21045	COG3903	Transcriptional regulator
G3H79_RS21045	COG3629	intracellular signal transduction
G3H79_RS21075	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS21080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G3H79_RS21095	COG0640	Transcriptional regulator
G3H79_RS21110	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
G3H79_RS21125	COG0346	lactoylglutathione lyase activity
G3H79_RS21185	COG4977	sequence-specific DNA binding
G3H79_RS21220	COG1686	Belongs to the peptidase S11 family
G3H79_RS21230	COG1653	transport
G3H79_RS21250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3H79_RS21290	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G3H79_RS21320	COG1192	Involved in chromosome partitioning
G3H79_RS21375	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS21395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G3H79_RS21430	COG1846	Transcriptional regulator
G3H79_RS21450	COG0477	Major facilitator Superfamily
G3H79_RS21455	COG1349	DNA-binding transcription factor activity
G3H79_RS21465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3H79_RS21465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3H79_RS21465	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G3H79_RS21485	COG1376	ErfK ybiS ycfS ynhG family protein
G3H79_RS21490	COG3191	aminopeptidase activity
G3H79_RS21505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G3H79_RS21515	COG1970	mechanosensitive ion channel activity
G3H79_RS21525	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G3H79_RS21540	COG3263	regulation of cellular component size
G3H79_RS21545	COG2366	antibiotic biosynthetic process
G3H79_RS21550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G3H79_RS21555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G3H79_RS21565	COG0315	cyclic pyranopterin monophosphate synthase activity
G3H79_RS21570	COG0315	cyclic pyranopterin monophosphate synthase activity
G3H79_RS21570	COG0521	Mo-molybdopterin cofactor biosynthetic process
G3H79_RS21575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3H79_RS21595	COG1595	DNA-templated transcription, initiation
G3H79_RS21600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3H79_RS21610	COG2205	protein histidine kinase activity
G3H79_RS21620	COG0708	Exodeoxyribonuclease III
G3H79_RS21635	COG2072	flavoprotein involved in K transport
G3H79_RS21640	COG2267	carboxylic ester hydrolase activity
G3H79_RS21645	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS21655	COG4946	Tricorn protease homolog
G3H79_RS21655	COG0793	Belongs to the peptidase S41A family
G3H79_RS21665	COG2409	Drug exporters of the RND superfamily
G3H79_RS21675	COG0310	cobalt ion transport
G3H79_RS21685	COG1122	ATPase activity
G3H79_RS21700	COG0442	prolyl-tRNA aminoacylation
G3H79_RS21730	COG0084	hydrolase, TatD family'
G3H79_RS21735	COG3584	3D domain protein
G3H79_RS21735	COG3583	domain protein
G3H79_RS21740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G3H79_RS21745	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G3H79_RS21750	COG0488	(ABC) transporter
G3H79_RS21790	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G3H79_RS21800	COG2197	response regulator
G3H79_RS21805	COG1846	Transcriptional regulator
G3H79_RS21810	COG4106	trans-aconitate 2-methyltransferase activity
G3H79_RS21820	COG1309	transcriptional regulator
G3H79_RS21830	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G3H79_RS21840	COG0193	aminoacyl-tRNA hydrolase activity
G3H79_RS21845	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G3H79_RS21850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G3H79_RS21855	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3H79_RS21865	COG4585	Histidine kinase
G3H79_RS21895	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3H79_RS21910	COG1136	(ABC) transporter
G3H79_RS21975	COG2124	cytochrome p450
G3H79_RS21990	COG0148	phosphopyruvate hydratase activity
G3H79_RS22015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3H79_RS22020	COG0577	efflux transmembrane transporter activity
G3H79_RS22025	COG1136	(ABC) transporter
G3H79_RS22065	COG0183	Belongs to the thiolase family
G3H79_RS22070	COG2755	lipolytic protein G-D-S-L family
G3H79_RS22090	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G3H79_RS22100	COG1174	glycine betaine transport
G3H79_RS22105	COG1174	glycine betaine transport
G3H79_RS22145	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G3H79_RS22160	COG1228	amidohydrolase
G3H79_RS22200	COG1794	racemase activity, acting on amino acids and derivatives
G3H79_RS22205	COG1191	sigma factor activity
G3H79_RS22210	COG1366	Belongs to the anti-sigma-factor antagonist family
G3H79_RS22245	COG3104	oligopeptide transport
G3H79_RS22250	COG0745	RESPONSE REGULATOR receiver
G3H79_RS22255	COG2205	protein histidine kinase activity
G3H79_RS22290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G3H79_RS22310	COG1316	TRANSCRIPTIONal
G3H79_RS22335	COG1316	TRANSCRIPTIONal
G3H79_RS22355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G3H79_RS22430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3H79_RS22435	COG2226	methyltransferase
G3H79_RS22485	COG0778	Nitroreductase
G3H79_RS22485	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G3H79_RS22490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G3H79_RS22525	COG1620	l-lactate permease
G3H79_RS22530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3H79_RS22535	COG2835	tetraacyldisaccharide 4'-kinase activity
G3H79_RS22545	COG1482	cell wall glycoprotein biosynthetic process
G3H79_RS22555	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3H79_RS22555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3H79_RS22555	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3H79_RS22560	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G3H79_RS22600	COG0714	Associated with various cellular activities
G3H79_RS22620	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
G3H79_RS22625	COG0745	RESPONSE REGULATOR receiver
G3H79_RS22635	COG0823	Involved in the tonB-independent uptake of proteins
G3H79_RS22645	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G3H79_RS22650	COG2197	response regulator
G3H79_RS22655	COG3214	Protein conserved in bacteria
G3H79_RS22665	COG0653	protein targeting
G3H79_RS22690	COG2902	Dehydrogenase
G3H79_RS22695	COG1216	Glycosyl transferase, family 2
G3H79_RS22710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3H79_RS22720	COG1215	transferase activity, transferring glycosyl groups
G3H79_RS22725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G3H79_RS22730	COG1134	teichoic acid transport
G3H79_RS22750	COG2197	response regulator
G3H79_RS22765	COG0577	efflux transmembrane transporter activity
G3H79_RS22765	COG1136	(ABC) transporter
G3H79_RS22780	COG1215	transferase activity, transferring glycosyl groups
G3H79_RS22790	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G3H79_RS22795	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G3H79_RS22800	COG0438	transferase activity, transferring glycosyl groups
G3H79_RS22815	COG0395	ABC-type sugar transport system, permease component
G3H79_RS22835	COG0515	serine threonine protein kinase
G3H79_RS22840	COG0515	serine threonine protein kinase
G3H79_RS22845	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G3H79_RS22860	COG2884	Cell division ATP-binding protein ftsE
G3H79_RS22870	COG0793	Belongs to the peptidase S41A family
G3H79_RS22875	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G3H79_RS22885	COG2027	D-alanyl-D-alanine carboxypeptidase
G3H79_RS22895	COG0583	DNA-binding transcription factor activity
G3H79_RS22985	COG3973	AAA domain
G3H79_RS22995	COG0776	regulation of translation
G3H79_RS23000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G3H79_RS23005	COG1678	Uncharacterized ACR, COG1678
G3H79_RS23010	COG0583	DNA-binding transcription factor activity
G3H79_RS23015	COG2814	Major facilitator Superfamily
G3H79_RS23025	COG3525	Glycosyl hydrolase, family 20, catalytic domain
G3H79_RS23120	COG3654	unkown
G3H79_RS23135	COG3480	Lon protease (S16) C-terminal proteolytic domain
G3H79_RS23150	COG1174	glycine betaine transport
G3H79_RS23155	COG0517	IMP dehydrogenase activity
G3H79_RS23155	COG1125	glycine betaine transport
G3H79_RS23170	COG3185	4-Hydroxyphenylpyruvate dioxygenase
G3H79_RS23180	COG0277	FAD linked oxidase domain protein
G3H79_RS23195	COG1714	RDD family
G3H79_RS23215	COG1335	isochorismatase
G3H79_RS23225	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G3H79_RS23235	COG1113	amino acid transport
G3H79_RS23250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3H79_RS23255	COG1120	ATPase activity
G3H79_RS23275	COG1234	tRNA 3'-trailer cleavage
G3H79_RS23280	COG1263	PTS System
G3H79_RS23285	COG1263	PTS System
G3H79_RS23290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G3H79_RS23295	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G3H79_RS23305	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G3H79_RS23335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3H79_RS23365	COG2733	membrane
G3H79_RS23475	COG3764	Sortase (surface protein transpeptidase)
G3H79_RS23485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3H79_RS23505	COG0706	membrane insertase activity
G3H79_RS23510	COG0179	Fumarylacetoacetate (FAA) hydrolase
G3H79_RS23520	COG4702	Belongs to the UPF0303 family
G3H79_RS23525	COG0673	inositol 2-dehydrogenase activity
G3H79_RS23540	COG2188	Transcriptional regulator
G3H79_RS23545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3H79_RS23625	COG2186	Transcriptional regulator
G3H79_RS23650	COG3397	chitin binding
G3H79_RS23655	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS23665	COG2197	response regulator
G3H79_RS23675	COG2409	Drug exporters of the RND superfamily
G3H79_RS23680	COG2197	response regulator
G3H79_RS23685	COG4585	Histidine kinase
G3H79_RS23695	COG3483	tryptophan 2,3-dioxygenase activity
G3H79_RS23735	COG1136	(ABC) transporter
G3H79_RS23755	COG3629	intracellular signal transduction
G3H79_RS23765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3H79_RS23770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3H79_RS23810	COG0134	indole-3-glycerol-phosphate synthase activity
G3H79_RS23815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3H79_RS23835	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G3H79_RS23845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G3H79_RS23880	COG1126	abc transporter atp-binding protein
G3H79_RS23885	COG0765	amino acid transport
G3H79_RS23890	COG0765	amino acid transport
G3H79_RS23895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3H79_RS23905	COG0154	amidase activity
G3H79_RS23925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS23930	COG0583	DNA-binding transcription factor activity
G3H79_RS23980	COG0406	alpha-ribazole phosphatase activity
G3H79_RS24005	COG0745	RESPONSE REGULATOR receiver
G3H79_RS24055	COG1309	transcriptional regulator
G3H79_RS24065	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G3H79_RS24070	COG4977	sequence-specific DNA binding
G3H79_RS24080	COG0589	response to stress
G3H79_RS24090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G3H79_RS24115	COG0076	glutamate decarboxylase activity
G3H79_RS24135	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS24150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3H79_RS24155	COG1309	transcriptional regulator
G3H79_RS24165	COG1946	Acyl-CoA thioesterase
G3H79_RS24185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3H79_RS24195	COG0028	Belongs to the TPP enzyme family
G3H79_RS24225	COG1472	Belongs to the glycosyl hydrolase 3 family
G3H79_RS24250	COG0456	acetyltransferase
G3H79_RS24250	COG1846	Transcriptional regulator
G3H79_RS24315	COG0673	inositol 2-dehydrogenase activity
G3H79_RS24345	COG1869	D-ribose catabolic process
G3H79_RS24350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3H79_RS24355	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3H79_RS24360	COG1129	ABC transporter
G3H79_RS24365	COG1609	Transcriptional regulator
G3H79_RS24370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G3H79_RS24400	COG1082	Xylose isomerase domain protein TIM barrel
G3H79_RS24405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3H79_RS24415	COG3718	enzyme involved in inositol metabolism
G3H79_RS24420	COG3962	Belongs to the TPP enzyme family
G3H79_RS24445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G3H79_RS24465	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3H79_RS24470	COG4106	trans-aconitate 2-methyltransferase activity
G3H79_RS24470	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G3H79_RS24475	COG1022	Amp-dependent synthetase and ligase
G3H79_RS24505	COG0629	single-stranded DNA binding
G3H79_RS24540	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G3H79_RS24570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3H79_RS24585	COG1486	melibiose metabolic process
G3H79_RS24590	COG0395	ABC-type sugar transport system, permease component
G3H79_RS24595	COG1175	transmembrane transport
G3H79_RS24605	COG1846	Transcriptional regulator
G3H79_RS24605	COG1940	carbohydrate kinase activity
G3H79_RS24610	COG0668	transmembrane transport
G3H79_RS24635	COG1846	Transcriptional regulator
G3H79_RS24640	COG0697	spore germination
G3H79_RS24665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3H79_RS24690	COG0583	DNA-binding transcription factor activity
G3H79_RS24695	COG2814	Major facilitator Superfamily
G3H79_RS24760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G3H79_RS24770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G3H79_RS24775	COG1113	amino acid transport
G3H79_RS24780	COG1113	amino acid transport
G3H79_RS24785	COG1268	BioY protein
G3H79_RS24795	COG1113	amino acid transport
G3H79_RS24810	COG4552	Acetyltransferase involved in intracellular survival and related
G3H79_RS24820	COG1136	(ABC) transporter
G3H79_RS24835	COG3594	Acyltransferase
G3H79_RS24845	COG0515	serine threonine protein kinase
G3H79_RS24845	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3H79_RS24860	COG0544	peptidyl-prolyl cis-trans isomerase activity
G3H79_RS24865	COG0740	serine-type endopeptidase activity
G3H79_RS24870	COG0740	serine-type endopeptidase activity
G3H79_RS24875	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G3H79_RS24900	COG0525	valine-tRNA ligase activity
G3H79_RS24920	COG2205	protein histidine kinase activity
G3H79_RS24930	COG4585	Histidine kinase
G3H79_RS24935	COG1077	Cell shape determining protein MreB Mrl
G3H79_RS24940	COG0285	dihydrofolate synthase activity
G3H79_RS24950	COG0105	UTP biosynthetic process
G3H79_RS24955	COG1077	Cell shape determining protein MreB Mrl
G3H79_RS24975	COG0772	Belongs to the SEDS family
G3H79_RS25005	COG1530	ribonuclease E activity
G3H79_RS25015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G3H79_RS25020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G3H79_RS25025	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G3H79_RS25035	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G3H79_RS25045	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G3H79_RS25060	COG0501	Belongs to the peptidase M48B family
G3H79_RS25065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G3H79_RS25075	COG0799	negative regulation of ribosome biogenesis
G3H79_RS25080	COG0588	phosphoglycerate mutase activity
G3H79_RS25095	COG0477	Major facilitator Superfamily
G3H79_RS25105	COG1051	belongs to the nudix hydrolase family
G3H79_RS25115	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G3H79_RS25125	COG0495	leucyl-tRNA aminoacylation
G3H79_RS25135	COG1307	EDD domain protein, DegV family
G3H79_RS25140	COG1555	photosystem II stabilization
G3H79_RS25145	COG1234	tRNA 3'-trailer cleavage
G3H79_RS25150	COG2353	YceI-like domain
G3H79_RS25165	COG0268	Binds directly to 16S ribosomal RNA
G3H79_RS25170	COG0481	GTPase activity
G3H79_RS25185	COG3437	response regulator, receiver
G3H79_RS25185	COG4999	Histidine kinase
G3H79_RS25185	COG3850	Histidine kinase
G3H79_RS25185	COG2205	protein histidine kinase activity
G3H79_RS25210	COG1420	regulation of RNA biosynthetic process
G3H79_RS25215	COG0484	heat shock protein binding
G3H79_RS25240	COG4946	Tricorn protease homolog
G3H79_RS25240	COG0793	Belongs to the peptidase S41A family
G3H79_RS25245	COG0537	adenosine 5'-monophosphoramidase activity
G3H79_RS25250	COG1234	tRNA 3'-trailer cleavage
G3H79_RS25255	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3H79_RS25260	COG4948	Mandelate Racemase Muconate Lactonizing
G3H79_RS25265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3H79_RS25275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G3H79_RS25285	COG2315	Protein conserved in bacteria
G3H79_RS25305	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G3H79_RS25325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3H79_RS25335	COG2409	Drug exporters of the RND superfamily
G3H79_RS25340	COG4585	Histidine kinase
G3H79_RS25345	COG2197	response regulator
G3H79_RS25355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3H79_RS25360	COG4608	Belongs to the ABC transporter superfamily
G3H79_RS25365	COG0444	Belongs to the ABC transporter superfamily
G3H79_RS25375	COG0747	negative chemotaxis
G3H79_RS25380	COG2186	Transcriptional regulator
G3H79_RS25390	COG3631	Ketosteroid isomerase-related protein
G3H79_RS25400	COG0583	DNA-binding transcription factor activity
G3H79_RS25405	COG2814	Major facilitator Superfamily
G3H79_RS25410	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G3H79_RS25415	COG2207	Transcriptional regulator
G3H79_RS25450	COG1381	Involved in DNA repair and RecF pathway recombination
G3H79_RS25455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G3H79_RS25465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G3H79_RS25470	COG1121	(ABC) transporter
G3H79_RS25475	COG3443	Belongs to the bacterial solute-binding protein 9 family
G3H79_RS25475	COG0803	Belongs to the bacterial solute-binding protein 9 family
G3H79_RS25480	COG0423	glycine-tRNA ligase activity
G3H79_RS25500	COG0667	Aldo Keto reductase
G3H79_RS25510	COG0477	Major facilitator Superfamily
G3H79_RS25515	COG0477	Major facilitator Superfamily
G3H79_RS25545	COG1940	carbohydrate kinase activity
G3H79_RS25545	COG1846	Transcriptional regulator
G3H79_RS25550	COG0574	Belongs to the PEP-utilizing enzyme family
G3H79_RS25550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3H79_RS25575	COG0531	amino acid
G3H79_RS25590	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS25600	COG2146	nitrite reductase [NAD(P)H] activity
G3H79_RS25600	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3H79_RS25605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3H79_RS25635	COG2205	protein histidine kinase activity
G3H79_RS25655	COG0243	molybdopterin cofactor binding
G3H79_RS25665	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G3H79_RS25675	COG0358	DNA primase activity
G3H79_RS25680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G3H79_RS25695	COG1070	Carbohydrate kinase
G3H79_RS25720	COG0515	serine threonine protein kinase
G3H79_RS25755	COG4139	cobalamin transport
G3H79_RS25775	COG3585	molybdate ion transport
G3H79_RS25800	COG1077	Cell shape determining protein MreB Mrl
G3H79_RS25820	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS25835	COG0596	Alpha beta hydrolase
G3H79_RS25845	COG2815	serine threonine protein kinase
G3H79_RS25845	COG0515	serine threonine protein kinase
G3H79_RS25885	COG4981	capsule polysaccharide biosynthetic process
G3H79_RS25920	COG2130	NADP-dependent
G3H79_RS25925	COG1764	response to oxidative stress
G3H79_RS25970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3H79_RS25975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3H79_RS25980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3H79_RS25995	COG1741	Belongs to the pirin family
G3H79_RS26010	COG0789	Transcriptional regulator
G3H79_RS26025	COG1309	transcriptional regulator
G3H79_RS26030	COG0477	Major facilitator Superfamily
G3H79_RS26040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3H79_RS26045	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3H79_RS26090	COG1358	cellular component organization or biogenesis
G3H79_RS26110	COG0800	Aldolase
G3H79_RS26180	COG2259	Doxx family
G3H79_RS26245	COG4122	O-methyltransferase activity
G3H79_RS26265	COG2124	cytochrome p450
G3H79_RS26270	COG0183	Belongs to the thiolase family
G3H79_RS26285	COG3845	ABC transporter
G3H79_RS26300	COG1657	PFAM Prenyltransferase squalene oxidase
G3H79_RS26305	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS26325	COG1309	transcriptional regulator
G3H79_RS26330	COG0438	transferase activity, transferring glycosyl groups
G3H79_RS26370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS26380	COG0860	N-Acetylmuramoyl-L-alanine amidase
G3H79_RS26395	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS26400	COG0183	Belongs to the thiolase family
G3H79_RS26410	COG2197	response regulator
G3H79_RS26415	COG4585	Histidine kinase
G3H79_RS26420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G3H79_RS26425	COG2197	response regulator
G3H79_RS26430	COG4585	Histidine kinase
G3H79_RS26435	COG2030	dehydratase
G3H79_RS26440	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G3H79_RS26445	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS26455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3H79_RS26460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G3H79_RS26475	COG0800	Aldolase
G3H79_RS26480	COG3022	response to hydroperoxide
G3H79_RS26535	COG1131	(ABC) transporter
G3H79_RS26585	COG0384	phenazine biosynthesis protein PhzF
G3H79_RS26600	COG3540	Alkaline phosphatase
G3H79_RS26610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G3H79_RS26615	COG2814	Major facilitator Superfamily
G3H79_RS26625	COG1834	amidinotransferase
G3H79_RS26655	COG0672	)-iron permease
G3H79_RS26660	COG1120	ATPase activity
G3H79_RS26665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3H79_RS26670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3H79_RS26730	COG1994	Peptidase M50
G3H79_RS26750	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G3H79_RS26755	COG0477	Major facilitator Superfamily
G3H79_RS26770	COG2814	Major facilitator Superfamily
G3H79_RS26775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3H79_RS26775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G3H79_RS26780	COG2132	Multicopper oxidase
G3H79_RS26795	COG2267	carboxylic ester hydrolase activity
G3H79_RS26800	COG1609	Transcriptional regulator
G3H79_RS26810	COG0395	ABC-type sugar transport system, permease component
G3H79_RS26815	COG4209	transmembrane transport
G3H79_RS26840	COG1959	2 iron, 2 sulfur cluster binding
G3H79_RS26845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3H79_RS26845	COG1017	nitric oxide dioxygenase activity
G3H79_RS26850	COG0174	glutamine synthetase
G3H79_RS26865	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G3H79_RS26875	COG1609	Transcriptional regulator
G3H79_RS26880	COG0366	Alpha amylase catalytic
G3H79_RS26925	COG0789	Transcriptional regulator
G3H79_RS26945	COG2197	response regulator
G3H79_RS26950	COG4585	Histidine kinase
G3H79_RS26955	COG2409	Drug exporters of the RND superfamily
G3H79_RS26965	COG0745	RESPONSE REGULATOR receiver
G3H79_RS27020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3H79_RS27025	COG1120	ATPase activity
G3H79_RS27075	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G3H79_RS27080	COG0321	lipoyl(octanoyl) transferase activity
G3H79_RS27140	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3H79_RS27150	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3H79_RS27155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3H79_RS27160	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G3H79_RS27165	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G3H79_RS27180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G3H79_RS27180	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G3H79_RS27185	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G3H79_RS27205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3H79_RS27210	COG2226	methyltransferase
G3H79_RS27230	COG4585	Histidine kinase
G3H79_RS27235	COG2197	response regulator
G3H79_RS27250	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G3H79_RS27270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3H79_RS27280	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3H79_RS27285	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3H79_RS27295	COG1376	ErfK ybiS ycfS ynhG family protein
G3H79_RS27305	COG1845	cytochrome c oxidase, subunit III
G3H79_RS27310	COG2010	Cytochrome c
G3H79_RS27315	COG0723	plastoquinol--plastocyanin reductase activity
G3H79_RS27320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G3H79_RS27325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3H79_RS27330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G3H79_RS27335	COG1929	Belongs to the glycerate kinase type-1 family
G3H79_RS27345	COG0745	RESPONSE REGULATOR receiver
G3H79_RS27350	COG2205	protein histidine kinase activity
G3H79_RS27400	COG0438	transferase activity, transferring glycosyl groups
G3H79_RS27420	COG0003	Pfam Anion-transporting ATPase
G3H79_RS27430	COG1940	carbohydrate kinase activity
G3H79_RS27460	COG2197	response regulator
G3H79_RS27465	COG0205	6-phosphofructokinase activity
G3H79_RS27470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3H79_RS27495	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G3H79_RS27505	COG2193	ferroxidase activity
G3H79_RS27510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3H79_RS27515	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G3H79_RS27520	COG0515	serine threonine protein kinase
G3H79_RS27520	COG2815	serine threonine protein kinase
G3H79_RS27525	COG2022	thiamine diphosphate biosynthetic process
G3H79_RS27535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3H79_RS27535	COG2022	thiamine diphosphate biosynthetic process
G3H79_RS27540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3H79_RS27550	COG0352	thiamine-phosphate diphosphorylase activity
G3H79_RS27575	COG1309	transcriptional regulator
G3H79_RS27585	COG1716	ATPase activity
G3H79_RS27585	COG1131	(ABC) transporter
G3H79_RS27585	COG0842	Transport permease protein
G3H79_RS27595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3H79_RS27615	COG0714	Associated with various cellular activities
G3H79_RS27625	COG0275	rRNA processing
G3H79_RS27640	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3H79_RS27650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G3H79_RS27655	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G3H79_RS27665	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G3H79_RS27670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G3H79_RS27675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G3H79_RS27690	COG1799	cell septum assembly
G3H79_RS27705	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G3H79_RS27730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G3H79_RS27760	COG0515	serine threonine protein kinase
G3H79_RS27785	COG0587	DNA-directed DNA polymerase activity
G3H79_RS27795	COG1432	Conserved Protein
G3H79_RS27835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G3H79_RS27840	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G3H79_RS27845	COG0131	Imidazoleglycerol-phosphate dehydratase
G3H79_RS27850	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G3H79_RS27855	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G3H79_RS27860	COG0251	oxidation-reduction process
G3H79_RS27865	COG0107	imidazoleglycerol-phosphate synthase activity
G3H79_RS27890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G3H79_RS27915	COG0134	indole-3-glycerol-phosphate synthase activity
G3H79_RS27925	COG0133	tryptophan synthase activity
G3H79_RS27930	COG0159	tryptophan synthase activity
G3H79_RS27940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G3H79_RS27950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3H79_RS27955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3H79_RS27975	COG1397	ADP-ribosylglycohydrolase
G3H79_RS27985	COG0070	glutamate synthase
G3H79_RS27985	COG0069	glutamate synthase activity
G3H79_RS27985	COG0067	glutamate synthase
G3H79_RS28000	COG1175	transmembrane transport
G3H79_RS28005	COG0395	ABC-type sugar transport system, permease component
G3H79_RS28030	COG2267	carboxylic ester hydrolase activity
G3H79_RS28040	COG2365	Tyrosine phosphatase family
G3H79_RS28045	COG1846	Transcriptional regulator
G3H79_RS28050	COG0477	Major facilitator Superfamily
G3H79_RS28055	COG1278	Cold shock
G3H79_RS28060	COG0513	Belongs to the DEAD box helicase family
G3H79_RS28065	COG1357	PFAM Pentapeptide repeats (8 copies)
G3H79_RS28080	COG2197	response regulator
G3H79_RS28085	COG3851	Histidine kinase
G3H79_RS28095	COG1470	cell adhesion involved in biofilm formation
G3H79_RS28095	COG0366	Alpha amylase catalytic
G3H79_RS28110	COG1605	Chorismate mutase
G3H79_RS28110	COG0287	Prephenate dehydrogenase
G3H79_RS28140	COG0737	Belongs to the 5'-nucleotidase family
G3H79_RS28155	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G3H79_RS28190	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3H79_RS28205	COG2050	protein possibly involved in aromatic compounds catabolism
G3H79_RS28235	COG1643	Atp-dependent helicase
G3H79_RS28240	COG2226	methyltransferase
G3H79_RS28265	COG0237	dephospho-CoA kinase activity
G3H79_RS28300	COG1288	antiporter activity
G3H79_RS28305	COG2267	carboxylic ester hydrolase activity
G3H79_RS28340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G3H79_RS28370	COG0402	S-adenosylhomocysteine deaminase activity
G3H79_RS28375	COG2124	cytochrome p450
G3H79_RS28445	COG0598	Magnesium transport protein CorA
G3H79_RS28450	COG2226	methyltransferase
G3H79_RS28455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G3H79_RS28455	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G3H79_RS28460	COG2313	pseudouridylate synthase activity
G3H79_RS28475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G3H79_RS28480	COG0584	glycerophosphoryl diester phosphodiesterase
G3H79_RS28490	COG0556	nucleotide-excision repair
G3H79_RS28510	COG0387	Pfam Sodium calcium exchanger
G3H79_RS28515	COG0477	Major facilitator Superfamily
G3H79_RS28520	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G3H79_RS28535	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3H79_RS28540	COG1024	Enoyl-CoA hydratase
G3H79_RS28545	COG2353	YceI-like domain
G3H79_RS28580	COG0322	excinuclease ABC activity
G3H79_RS28585	COG1660	Displays ATPase and GTPase activities
G3H79_RS28590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G3H79_RS28595	COG1481	regulation of sporulation
G3H79_RS28605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G3H79_RS28610	COG0126	phosphoglycerate kinase activity
G3H79_RS28615	COG0149	triose-phosphate isomerase activity
G3H79_RS28620	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G3H79_RS28635	COG0166	Belongs to the GPI family
G3H79_RS28645	COG0363	glucosamine-6-phosphate deaminase activity
G3H79_RS28660	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G3H79_RS28670	COG0109	protoheme IX farnesyltransferase activity
G3H79_RS28690	COG1612	heme a metabolic process
G3H79_RS28700	COG1131	(ABC) transporter
G3H79_RS28705	COG2116	formate transmembrane transporter activity
G3H79_RS28710	COG2746	aminoglycoside 3-N-acetyltransferase activity
G3H79_RS28725	COG0719	Fe-S assembly protein
G3H79_RS28735	COG0396	ATPase activity
G3H79_RS28740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G3H79_RS28745	COG0822	iron-sulfur transferase activity
G3H79_RS28760	COG3226	Transcriptional regulator
G3H79_RS28775	COG2171	N-acyltransferase activity
G3H79_RS28785	COG1595	DNA-templated transcription, initiation
G3H79_RS28795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3H79_RS28890	COG1063	alcohol dehydrogenase
G3H79_RS28895	COG0395	ABC-type sugar transport system, permease component
G3H79_RS28910	COG1349	DNA-binding transcription factor activity
G3H79_RS28920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G3H79_RS28925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3H79_RS28945	COG1802	Transcriptional regulator
G3H79_RS28950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3H79_RS28965	COG1695	Transcriptional regulator
G3H79_RS28975	COG0768	penicillin binding
G3H79_RS28980	COG2197	response regulator
G3H79_RS28985	COG4585	Histidine kinase
G3H79_RS28995	COG1414	Transcriptional regulator
G3H79_RS29015	COG1733	regulation of RNA biosynthetic process
G3H79_RS29025	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G3H79_RS29030	COG1846	Transcriptional regulator
G3H79_RS29035	COG1902	pentaerythritol trinitrate reductase activity
G3H79_RS29040	COG5285	phytanoyl-CoA dioxygenase
G3H79_RS29045	COG1917	Cupin 2, conserved barrel domain protein
G3H79_RS29050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G3H79_RS29055	COG0456	acetyltransferase
G3H79_RS29060	COG2318	DinB family
G3H79_RS29065	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G3H79_RS29075	COG3119	arylsulfatase activity
G3H79_RS29125	COG1797	cobyrinic acid a,c-diamide synthase activity
G3H79_RS29130	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
G3H79_RS29145	COG1492	cobalamin metabolic process
G3H79_RS29150	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G3H79_RS29185	COG0235	Class ii aldolase
G3H79_RS29210	COG0488	(ABC) transporter
G3H79_RS29320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3H79_RS29330	COG1404	Belongs to the peptidase S8 family
G3H79_RS29335	COG1404	Belongs to the peptidase S8 family
G3H79_RS29345	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3H79_RS29350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G3H79_RS29370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G3H79_RS29385	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS29390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G3H79_RS29400	COG2186	Transcriptional regulator
G3H79_RS29420	COG0560	Phosphoserine phosphatase
G3H79_RS29420	COG3830	Belongs to the UPF0237 family
G3H79_RS29430	COG1716	ATPase activity
G3H79_RS29430	COG1131	(ABC) transporter
G3H79_RS29430	COG0842	Transport permease protein
G3H79_RS29440	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G3H79_RS29455	COG2197	response regulator
G3H79_RS29475	COG1119	ATPase activity
G3H79_RS29495	COG1881	PFAM PEBP family protein
G3H79_RS29505	COG2094	Belongs to the DNA glycosylase MPG family
G3H79_RS29535	COG0647	UMP catabolic process
G3H79_RS29545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3H79_RS29550	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3H79_RS29555	COG1120	ATPase activity
G3H79_RS29575	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G3H79_RS29585	COG0497	DNA recombination
G3H79_RS29595	COG0297	glycogen (starch) synthase activity
G3H79_RS29605	COG3387	PFAM Glycoside hydrolase 15-related
G3H79_RS29610	COG0504	CTP synthase activity
G3H79_RS29615	COG0494	nUDIX hydrolase
G3H79_RS29625	COG0686	Belongs to the AlaDH PNT family
G3H79_RS29640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G3H79_RS29645	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G3H79_RS29650	COG1187	pseudouridine synthase activity
G3H79_RS29690	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G3H79_RS29700	COG1160	GTP binding
G3H79_RS29715	COG1652	LysM domain
G3H79_RS29720	COG3583	domain protein
G3H79_RS29750	COG0438	transferase activity, transferring glycosyl groups
G3H79_RS29775	COG0671	phosphoesterase, PA-phosphatase related
G3H79_RS29785	COG0477	Major facilitator Superfamily
G3H79_RS29790	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS29795	COG1799	cell septum assembly
G3H79_RS29820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS29850	COG0747	negative chemotaxis
G3H79_RS29870	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS29870	COG1454	alcohol dehydrogenase
G3H79_RS29885	COG0587	DNA-directed DNA polymerase activity
G3H79_RS29900	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G3H79_RS29910	COG4565	transcriptional regulatory protein
G3H79_RS29950	COG1725	Transcriptional regulator
G3H79_RS29980	COG0463	Glycosyl transferase, family 2
G3H79_RS29995	COG2755	lipolytic protein G-D-S-L family
G3H79_RS30020	COG1595	DNA-templated transcription, initiation
G3H79_RS30050	COG0477	Major facilitator Superfamily
G3H79_RS30060	COG2188	Transcriptional regulator
G3H79_RS30065	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G3H79_RS30070	COG1309	transcriptional regulator
G3H79_RS30075	COG0243	molybdopterin cofactor binding
G3H79_RS30080	COG2851	Citrate transporter
G3H79_RS30105	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS30165	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS30170	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS30205	COG2149	membrane
G3H79_RS30210	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
G3H79_RS30230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3H79_RS30245	COG3265	gluconokinase activity
G3H79_RS30250	COG2186	Transcriptional regulator
G3H79_RS30260	COG3012	SEC-C Motif Domain Protein
G3H79_RS30275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3H79_RS30300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G3H79_RS30305	COG0667	Aldo Keto reductase
G3H79_RS30310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS30320	COG0598	Magnesium transport protein CorA
G3H79_RS30325	COG0406	alpha-ribazole phosphatase activity
G3H79_RS30340	COG0215	cysteine-tRNA ligase activity
G3H79_RS30360	COG2186	Transcriptional regulator
G3H79_RS30370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3H79_RS30375	COG0402	S-adenosylhomocysteine deaminase activity
G3H79_RS30390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G3H79_RS30395	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3H79_RS30400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G3H79_RS30405	COG1414	Transcriptional regulator
G3H79_RS30410	COG1410	methionine synthase
G3H79_RS30410	COG0646	methionine synthase
G3H79_RS30420	COG0747	negative chemotaxis
G3H79_RS30425	COG4166	transmembrane transport
G3H79_RS30430	COG2197	response regulator
G3H79_RS30440	COG0517	IMP dehydrogenase activity
G3H79_RS30440	COG1994	Peptidase M50
G3H79_RS30465	COG1222	aaa ATPase
G3H79_RS30470	COG4122	O-methyltransferase activity
G3H79_RS30485	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G3H79_RS30490	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G3H79_RS30495	COG1609	Transcriptional regulator
G3H79_RS30505	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
G3H79_RS30540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3H79_RS30545	COG0805	protein transport
G3H79_RS30600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3H79_RS30605	COG0517	IMP dehydrogenase activity
G3H79_RS30605	COG4175	Glycine betaine
G3H79_RS30635	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G3H79_RS30640	COG0531	amino acid
G3H79_RS30650	COG0174	glutamine synthetase
G3H79_RS30655	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS30700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G3H79_RS30705	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G3H79_RS30710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G3H79_RS30715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3H79_RS30720	COG5002	protein histidine kinase activity
G3H79_RS30725	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G3H79_RS30730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3H79_RS30730	COG0072	phenylalanine-tRNA ligase activity
G3H79_RS30760	COG1649	PFAM Uncharacterised BCR, COG1649
G3H79_RS30770	COG0697	spore germination
G3H79_RS30775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3H79_RS30800	COG0667	Aldo Keto reductase
G3H79_RS30805	COG0596	Alpha beta hydrolase
G3H79_RS30825	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G3H79_RS30830	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G3H79_RS30835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G3H79_RS30840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3H79_RS30845	COG1438	arginine binding
G3H79_RS30850	COG0385	Bile acid
G3H79_RS30860	COG0137	argininosuccinate synthase activity
G3H79_RS30865	COG0165	Argininosuccinate lyase
G3H79_RS30880	COG0477	Major facilitator Superfamily
G3H79_RS30885	COG0204	Acyl-transferase
G3H79_RS30885	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS30890	COG0584	glycerophosphoryl diester phosphodiesterase
G3H79_RS30920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G3H79_RS30925	COG2011	ABC-type metal ion transport system permease component
G3H79_RS30930	COG1464	Belongs to the NlpA lipoprotein family
G3H79_RS30935	COG1464	Belongs to the NlpA lipoprotein family
G3H79_RS30950	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G3H79_RS30955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G3H79_RS30955	COG1648	precorrin-2 dehydrogenase activity
G3H79_RS31015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G3H79_RS31075	COG5002	protein histidine kinase activity
G3H79_RS31075	COG2176	DNA-directed DNA polymerase activity
G3H79_RS31090	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G3H79_RS31115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G3H79_RS31120	COG1560	Kdo2-lipid A biosynthetic process
G3H79_RS31125	COG0438	transferase activity, transferring glycosyl groups
G3H79_RS31135	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
G3H79_RS31140	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
G3H79_RS31145	COG0217	transcriptional regulatory protein
G3H79_RS31150	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G3H79_RS31155	COG0632	four-way junction helicase activity
G3H79_RS31160	COG2255	four-way junction helicase activity
G3H79_RS31170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3H79_RS31175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3H79_RS31180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G3H79_RS31185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3H79_RS31190	COG1196	nuclear chromosome segregation
G3H79_RS31195	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G3H79_RS31205	COG0124	histidyl-tRNA synthetase
G3H79_RS31210	COG2197	response regulator
G3H79_RS31215	COG4585	Histidine kinase
G3H79_RS31225	COG1131	(ABC) transporter
G3H79_RS31240	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G3H79_RS31260	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G3H79_RS31265	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G3H79_RS31275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G3H79_RS31280	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G3H79_RS31285	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G3H79_RS31290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G3H79_RS31300	COG0006	proline dipeptidase activity
G3H79_RS31305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G3H79_RS31310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3H79_RS31320	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G3H79_RS31325	COG0540	Belongs to the ATCase OTCase family
G3H79_RS31330	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G3H79_RS31340	COG0505	Belongs to the CarA family
G3H79_RS31345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G3H79_RS31350	COG0167	dihydroorotate dehydrogenase activity
G3H79_RS31355	COG0284	orotidine-5'-phosphate decarboxylase activity
G3H79_RS31365	COG0194	GDP metabolic process
G3H79_RS31380	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G3H79_RS31415	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G3H79_RS31425	COG2409	Drug exporters of the RND superfamily
G3H79_RS31430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G3H79_RS31435	COG2390	Transcriptional regulator
G3H79_RS31455	COG0531	amino acid
G3H79_RS31470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3H79_RS31485	COG2233	PERMEase
G3H79_RS31495	COG0738	Major facilitator superfamily
G3H79_RS31500	COG1940	carbohydrate kinase activity
G3H79_RS31500	COG1846	Transcriptional regulator
G3H79_RS31525	COG3201	nicotinamide mononucleotide transporter
G3H79_RS31530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G3H79_RS31530	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G3H79_RS31535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G3H79_RS31540	COG0140	phosphoribosyl-ATP diphosphatase activity
G3H79_RS31545	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G3H79_RS31565	COG2197	response regulator
G3H79_RS31620	COG1309	transcriptional regulator
G3H79_RS31630	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS31665	COG0463	Glycosyl transferase, family 2
G3H79_RS31670	COG3030	protein affecting phage T7 exclusion by the F plasmid
G3H79_RS31680	COG2270	Major facilitator Superfamily
G3H79_RS31725	COG0438	transferase activity, transferring glycosyl groups
G3H79_RS31735	COG1984	allophanate hydrolase subunit 2
G3H79_RS31740	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G3H79_RS31745	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3H79_RS31750	COG4336	lyase activity
G3H79_RS31755	COG2814	Major facilitator Superfamily
G3H79_RS31785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3H79_RS31800	COG1414	Transcriptional regulator
G3H79_RS31810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3H79_RS31845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3H79_RS31850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G3H79_RS31855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3H79_RS31865	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
G3H79_RS31880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3H79_RS31890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3H79_RS31920	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G3H79_RS31960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G3H79_RS31970	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G3H79_RS31970	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G3H79_RS32000	COG0384	phenazine biosynthesis protein PhzF
G3H79_RS32010	COG1695	Transcriptional regulator
G3H79_RS32020	COG2890	protein-(glutamine-N5) methyltransferase activity
G3H79_RS32055	COG0697	spore germination
G3H79_RS32105	COG0747	negative chemotaxis
G3H79_RS32110	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G3H79_RS32155	COG0583	DNA-binding transcription factor activity
G3H79_RS32215	COG1968	undecaprenyl-diphosphatase activity
G3H79_RS32230	COG0183	Belongs to the thiolase family
G3H79_RS32245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3H79_RS32285	COG1472	Belongs to the glycosyl hydrolase 3 family
G3H79_RS32335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G3H79_RS32390	COG0745	RESPONSE REGULATOR receiver
G3H79_RS32395	COG2205	protein histidine kinase activity
G3H79_RS32425	COG1832	CoA-binding protein
G3H79_RS32460	COG1739	Uncharacterized protein family UPF0029
G3H79_RS32465	COG0842	Transport permease protein
G3H79_RS32465	COG1131	(ABC) transporter
G3H79_RS32465	COG1716	ATPase activity
G3H79_RS32490	COG0420	3'-5' exonuclease activity
G3H79_RS32495	COG0419	ATPase involved in DNA repair
G3H79_RS32500	COG1522	sequence-specific DNA binding
G3H79_RS32515	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS32535	COG0346	lactoylglutathione lyase activity
G3H79_RS32545	COG1595	DNA-templated transcription, initiation
G3H79_RS32555	COG2188	Transcriptional regulator
G3H79_RS32560	COG1940	carbohydrate kinase activity
G3H79_RS32565	COG2197	response regulator
G3H79_RS32570	COG4585	Histidine kinase
G3H79_RS32590	COG1024	Enoyl-CoA hydratase
G3H79_RS32620	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G3H79_RS32655	COG4585	Histidine kinase
G3H79_RS32660	COG0586	Pfam SNARE associated Golgi protein
G3H79_RS32665	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G3H79_RS32670	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS32705	COG0583	DNA-binding transcription factor activity
G3H79_RS32725	COG0456	acetyltransferase
G3H79_RS32755	COG2226	methyltransferase
G3H79_RS32760	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G3H79_RS32765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3H79_RS32770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G3H79_RS32810	COG0740	serine-type endopeptidase activity
G3H79_RS32820	COG0831	urea catabolic process
G3H79_RS32825	COG0832	Belongs to the urease beta subunit family
G3H79_RS32830	COG0804	urea catabolic process
G3H79_RS32840	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G3H79_RS32845	COG0829	nickel cation binding
G3H79_RS32895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G3H79_RS32900	COG0204	Acyl-transferase
G3H79_RS32915	COG0205	6-phosphofructokinase activity
G3H79_RS32920	COG3442	glutamine amidotransferase
G3H79_RS32930	COG0242	peptide deformylase activity
G3H79_RS32940	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS32960	COG1335	isochorismatase
G3H79_RS32970	COG2860	membrane
G3H79_RS33010	COG0367	asparagine synthase
G3H79_RS33020	COG0577	efflux transmembrane transporter activity
G3H79_RS33020	COG1136	(ABC) transporter
G3H79_RS33030	COG0583	DNA-binding transcription factor activity
G3H79_RS33035	COG4941	Belongs to the sigma-70 factor family
G3H79_RS33070	COG2409	Drug exporters of the RND superfamily
G3H79_RS33080	COG2175	clavaminate synthase activity
G3H79_RS33105	COG2084	Dehydrogenase
G3H79_RS33145	COG0330	HflC and HflK could
G3H79_RS33175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3H79_RS33190	COG3384	dioxygenase
G3H79_RS33200	COG1285	pathogenesis
G3H79_RS33210	COG1116	anion transmembrane transporter activity
G3H79_RS33225	COG0640	Transcriptional regulator
G3H79_RS33230	COG2910	NAD(P)H-binding
G3H79_RS33240	COG1609	Transcriptional regulator
G3H79_RS33245	COG2182	Extracellular solute-binding protein
G3H79_RS33250	COG1175	transmembrane transport
G3H79_RS33255	COG3833	ABC-type maltose transport systems, permease component
G3H79_RS33260	COG0366	Alpha amylase catalytic
G3H79_RS33290	COG5297	Belongs to the glycosyl hydrolase family 6
G3H79_RS33295	COG1501	Belongs to the glycosyl hydrolase 31 family
G3H79_RS33300	COG1595	DNA-templated transcription, initiation
G3H79_RS33310	COG2072	flavoprotein involved in K transport
G3H79_RS33335	COG1937	Protein conserved in bacteria
G3H79_RS33350	COG4214	carbohydrate transport
G3H79_RS33380	COG1414	Transcriptional regulator
G3H79_RS33415	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G3H79_RS33425	COG2409	Drug exporters of the RND superfamily
G3H79_RS33435	COG0574	Belongs to the PEP-utilizing enzyme family
G3H79_RS33435	COG3848	Pyruvate phosphate dikinase
G3H79_RS33490	COG0251	oxidation-reduction process
G3H79_RS33495	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS33510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3H79_RS33530	COG1116	anion transmembrane transporter activity
G3H79_RS33535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3H79_RS33540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3H79_RS33545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS33550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3H79_RS33570	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3H79_RS33575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G3H79_RS33605	COG1609	Transcriptional regulator
G3H79_RS33630	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G3H79_RS33635	COG0277	FAD linked oxidase domain protein
G3H79_RS33635	COG0247	lactate metabolic process
G3H79_RS33660	COG0583	DNA-binding transcription factor activity
G3H79_RS33670	COG2755	lipolytic protein G-D-S-L family
G3H79_RS33670	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G3H79_RS33675	COG0745	RESPONSE REGULATOR receiver
G3H79_RS33680	COG2205	protein histidine kinase activity
G3H79_RS33735	COG0789	Transcriptional regulator
G3H79_RS33740	COG1902	pentaerythritol trinitrate reductase activity
G3H79_RS33760	COG2807	transmembrane transport
G3H79_RS33765	COG2186	Transcriptional regulator
G3H79_RS33795	COG1309	transcriptional regulator
G3H79_RS33810	COG0671	phosphoesterase, PA-phosphatase related
G3H79_RS33835	COG0584	glycerophosphoryl diester phosphodiesterase
G3H79_RS33850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS33885	COG0072	phenylalanine-tRNA ligase activity
G3H79_RS33885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3H79_RS33890	COG0204	Acyl-transferase
G3H79_RS33910	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G3H79_RS33925	COG0515	serine threonine protein kinase
G3H79_RS33965	COG3345	alpha-galactosidase
G3H79_RS33980	COG0395	ABC-type sugar transport system, permease component
G3H79_RS33990	COG0494	nUDIX hydrolase
G3H79_RS34010	COG4585	Histidine kinase
G3H79_RS34015	COG2197	response regulator
G3H79_RS34025	COG0445	tRNA wobble uridine modification
G3H79_RS34030	COG4585	Histidine kinase
G3H79_RS34035	COG2197	response regulator
G3H79_RS34065	COG2223	nitrite transmembrane transporter activity
G3H79_RS34070	COG1940	carbohydrate kinase activity
G3H79_RS34120	COG1136	(ABC) transporter
G3H79_RS34125	COG0577	efflux transmembrane transporter activity
G3H79_RS34150	COG1349	DNA-binding transcription factor activity
G3H79_RS34185	COG1215	transferase activity, transferring glycosyl groups
G3H79_RS34190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G3H79_RS34225	COG2813	Specifically methylates the guanine in position
G3H79_RS34235	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3H79_RS34240	COG1595	DNA-templated transcription, initiation
G3H79_RS34250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G3H79_RS34265	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3H79_RS34265	COG1902	pentaerythritol trinitrate reductase activity
G3H79_RS34305	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS34330	COG1461	Dihydroxyacetone kinase
G3H79_RS34335	COG2376	Dihydroxyacetone kinase
G3H79_RS34340	COG1309	transcriptional regulator
G3H79_RS34370	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3H79_RS34380	COG1752	Esterase of the alpha-beta hydrolase superfamily
G3H79_RS34405	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G3H79_RS34425	COG3619	membrane
G3H79_RS34430	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS34435	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS34460	COG0515	serine threonine protein kinase
G3H79_RS34495	COG1473	amidohydrolase
G3H79_RS34505	COG2070	2-Nitropropane dioxygenase
G3H79_RS34520	COG2366	antibiotic biosynthetic process
G3H79_RS34570	COG1335	isochorismatase
G3H79_RS34605	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS34630	COG0431	NADPH-dependent FMN reductase
G3H79_RS34685	COG0309	Hydrogenase expression formation protein (HypE)
G3H79_RS34695	COG0517	IMP dehydrogenase activity
G3H79_RS34695	COG0516	GMP reductase activity
G3H79_RS34700	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
G3H79_RS34735	COG0517	IMP dehydrogenase activity
G3H79_RS34735	COG0516	GMP reductase activity
G3H79_RS34740	COG0045	succinate-CoA ligase (ADP-forming) activity
G3H79_RS34740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3H79_RS34740	COG1042	CoA-binding domain protein
G3H79_RS34750	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
G3H79_RS34760	COG0589	response to stress
G3H79_RS34775	COG1652	LysM domain
G3H79_RS34805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G3H79_RS34850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3H79_RS34855	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G3H79_RS34860	COG2326	polyphosphate kinase activity
G3H79_RS34865	COG0589	response to stress
G3H79_RS34870	COG0589	response to stress
G3H79_RS34890	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G3H79_RS34895	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS34895	COG1454	alcohol dehydrogenase
G3H79_RS34900	COG0574	Belongs to the PEP-utilizing enzyme family
G3H79_RS34900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3H79_RS34910	COG2366	antibiotic biosynthetic process
G3H79_RS34915	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS34925	COG4221	oxidoreductase activity
G3H79_RS34935	COG0583	DNA-binding transcription factor activity
G3H79_RS34950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3H79_RS34955	COG3170	Tfp pilus assembly protein FimV
G3H79_RS34960	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3H79_RS34965	COG1605	Chorismate mutase
G3H79_RS34975	COG1024	Enoyl-CoA hydratase
G3H79_RS35025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3H79_RS35030	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3H79_RS35035	COG1120	ATPase activity
G3H79_RS35040	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G3H79_RS35045	COG1132	(ABC) transporter
G3H79_RS35055	COG1132	(ABC) transporter
G3H79_RS35070	COG2382	esterase
G3H79_RS35085	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G3H79_RS35095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G3H79_RS35100	COG3486	L-lysine 6-monooxygenase (NADPH) activity
G3H79_RS35110	COG0778	Nitroreductase
G3H79_RS35145	COG2226	methyltransferase
G3H79_RS35150	COG0640	Transcriptional regulator
G3H79_RS35195	COG1846	Transcriptional regulator
G3H79_RS35195	COG1940	carbohydrate kinase activity
G3H79_RS35200	COG1129	ABC transporter
G3H79_RS35205	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3H79_RS35325	COG2197	response regulator
G3H79_RS35330	COG4585	Histidine kinase
G3H79_RS35340	COG1131	(ABC) transporter
G3H79_RS35350	COG0181	hydroxymethylbilane synthase activity
G3H79_RS35470	COG0039	L-malate dehydrogenase activity
G3H79_RS35515	COG1793	dna ligase
G3H79_RS35535	COG0825	malonyl-CoA metabolic process
G3H79_RS35535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G3H79_RS35550	COG0673	inositol 2-dehydrogenase activity
G3H79_RS35555	COG1686	Belongs to the peptidase S11 family
G3H79_RS35560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G3H79_RS35565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3H79_RS35580	COG1309	transcriptional regulator
G3H79_RS35605	COG2207	Transcriptional regulator
G3H79_RS35620	COG0386	Belongs to the glutathione peroxidase family
G3H79_RS35675	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
G3H79_RS35680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3H79_RS35685	COG2205	protein histidine kinase activity
G3H79_RS35690	COG0745	RESPONSE REGULATOR receiver
G3H79_RS35695	COG2706	6-phosphogluconolactonase activity
G3H79_RS35710	COG0285	dihydrofolate synthase activity
G3H79_RS35715	COG0523	cobalamin synthesis protein
G3H79_RS35735	COG0789	Transcriptional regulator
G3H79_RS35740	COG1819	glycosyl
G3H79_RS35750	COG0435	Glutathione S-transferase
G3H79_RS35765	COG1309	transcriptional regulator
G3H79_RS35825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS35850	COG0667	Aldo Keto reductase
G3H79_RS35860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3H79_RS35910	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G3H79_RS35915	COG3739	integral membrane protein
G3H79_RS35945	COG0590	tRNA wobble adenosine to inosine editing
G3H79_RS35950	COG2076	Multidrug Resistance protein
G3H79_RS35980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3H79_RS35990	COG2723	6-phospho-beta-galactosidase activity
G3H79_RS35995	COG0395	ABC-type sugar transport system, permease component
G3H79_RS36000	COG1175	transmembrane transport
G3H79_RS36010	COG1940	carbohydrate kinase activity
G3H79_RS36015	COG2267	carboxylic ester hydrolase activity
G3H79_RS36025	COG1132	(ABC) transporter
G3H79_RS36040	COG1309	transcriptional regulator
G3H79_RS36070	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS36100	COG2197	response regulator
G3H79_RS36105	COG4585	Histidine kinase
G3H79_RS36135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3H79_RS36190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G3H79_RS36195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G3H79_RS36205	COG1250	3-hydroxyacyl-CoA dehydrogenase
G3H79_RS36220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3H79_RS36225	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS36230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3H79_RS36265	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G3H79_RS36335	COG0318	PFAM AMP-dependent synthetase and ligase
G3H79_RS36340	COG3629	intracellular signal transduction
G3H79_RS36340	COG3903	Transcriptional regulator
G3H79_RS36400	COG1595	DNA-templated transcription, initiation
G3H79_RS36420	COG4585	Histidine kinase
G3H79_RS36425	COG2197	response regulator
G3H79_RS36435	COG2409	Drug exporters of the RND superfamily
G3H79_RS36465	COG0596	Alpha beta hydrolase
G3H79_RS36565	COG1349	DNA-binding transcription factor activity
G3H79_RS36575	COG0494	nUDIX hydrolase
G3H79_RS36590	COG1132	(ABC) transporter
G3H79_RS36675	COG0583	DNA-binding transcription factor activity
G3H79_RS36780	COG1302	Protein conserved in bacteria
G3H79_RS36795	COG1686	Belongs to the peptidase S11 family
G3H79_RS36800	COG2205	protein histidine kinase activity
G3H79_RS36805	COG0745	RESPONSE REGULATOR receiver
G3H79_RS36835	COG2226	methyltransferase
G3H79_RS36880	COG3903	Transcriptional regulator
G3H79_RS36880	COG3629	intracellular signal transduction
G3H79_RS36970	COG2409	Drug exporters of the RND superfamily
G3H79_RS36975	COG4585	Histidine kinase
G3H79_RS36980	COG2197	response regulator
G3H79_RS37060	COG1472	Belongs to the glycosyl hydrolase 3 family
G3H79_RS37065	COG0395	ABC-type sugar transport system, permease component
G3H79_RS37080	COG1609	Transcriptional regulator
G3H79_RS37090	COG3693	PFAM glycoside hydrolase, family 10
G3H79_RS37135	COG4608	Belongs to the ABC transporter superfamily
G3H79_RS37145	COG0601	transmembrane transport
G3H79_RS37150	COG0747	negative chemotaxis
G3H79_RS37155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3H79_RS37165	COG2508	Transcriptional regulator
G3H79_RS37165	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
G3H79_RS37200	COG1609	Transcriptional regulator
G3H79_RS37210	COG0395	ABC-type sugar transport system, permease component
G3H79_RS37230	COG3291	Pkd domain containing protein
G3H79_RS37240	COG2197	response regulator
G3H79_RS37245	COG4585	Histidine kinase
G3H79_RS37250	COG1309	transcriptional regulator
G3H79_RS37265	COG2197	response regulator
G3H79_RS37270	COG4585	Histidine kinase
G3H79_RS37295	COG1309	transcriptional regulator
G3H79_RS37300	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS37310	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS37325	COG2318	DinB family
G3H79_RS37330	COG1349	DNA-binding transcription factor activity
G3H79_RS37335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G3H79_RS37340	COG0191	fructose-bisphosphate aldolase activity
G3H79_RS37345	COG2318	DinB family
G3H79_RS37365	COG2197	response regulator
G3H79_RS37380	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS37395	COG0483	inositol monophosphate 1-phosphatase activity
G3H79_RS37400	COG0583	DNA-binding transcription factor activity
G3H79_RS37405	COG4106	trans-aconitate 2-methyltransferase activity
G3H79_RS37450	COG1595	DNA-templated transcription, initiation
G3H79_RS37460	COG1051	belongs to the nudix hydrolase family
G3H79_RS37470	COG1733	regulation of RNA biosynthetic process
G3H79_RS37495	COG1660	Displays ATPase and GTPase activities
G3H79_RS37505	COG4941	Belongs to the sigma-70 factor family
G3H79_RS37510	COG3795	YCII-related domain
G3H79_RS37525	COG0583	DNA-binding transcription factor activity
G3H79_RS37535	COG2409	Drug exporters of the RND superfamily
G3H79_RS37540	COG4585	Histidine kinase
G3H79_RS37550	COG0477	Major facilitator Superfamily
G3H79_RS37580	COG2814	Major facilitator Superfamily
G3H79_RS37605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G3H79_RS37635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G3H79_RS37705	COG0596	Alpha beta hydrolase
G3H79_RS37720	COG0488	(ABC) transporter
G3H79_RS37730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G3H79_RS37745	COG4106	trans-aconitate 2-methyltransferase activity
G3H79_RS37750	COG3800	Transcriptional regulator
G3H79_RS37750	COG1396	sequence-specific DNA binding
G3H79_RS37760	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G3H79_RS37795	COG0367	asparagine synthase
G3H79_RS37875	COG4585	Histidine kinase
G3H79_RS37880	COG2197	response regulator
G3H79_RS37930	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G3H79_RS37935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G3H79_RS37955	COG2945	thiolester hydrolase activity
G3H79_RS37955	COG0596	Alpha beta hydrolase
G3H79_RS37995	COG4608	Belongs to the ABC transporter superfamily
G3H79_RS38005	COG0601	transmembrane transport
G3H79_RS38020	COG0006	proline dipeptidase activity
G3H79_RS38045	COG3938	Belongs to the proline racemase family
G3H79_RS38050	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS38055	COG1802	Transcriptional regulator
G3H79_RS38065	COG1522	sequence-specific DNA binding
G3H79_RS38070	COG0252	asparaginase activity
G3H79_RS38145	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3H79_RS38155	COG1733	regulation of RNA biosynthetic process
G3H79_RS38160	COG2084	Dehydrogenase
G3H79_RS38175	COG2318	DinB family
G3H79_RS38180	COG2124	cytochrome p450
G3H79_RS38200	COG2259	Doxx family
G3H79_RS38205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G3H79_RS38220	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G3H79_RS38250	COG1609	Transcriptional regulator
G3H79_RS38255	COG1957	nucleoside hydrolase
G3H79_RS38275	COG0789	Transcriptional regulator
G3H79_RS38350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G3H79_RS38360	COG1280	lysine exporter protein (LysE YggA)
G3H79_RS38365	COG0154	amidase activity
G3H79_RS38375	COG1796	DNA polymerase
G3H79_RS38375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G3H79_RS38380	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS38395	COG0477	Major facilitator Superfamily
G3H79_RS38430	COG2197	response regulator
G3H79_RS38435	COG4585	Histidine kinase
G3H79_RS38505	COG2223	nitrite transmembrane transporter activity
G3H79_RS38535	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
G3H79_RS38535	COG3408	Glycogen debranching enzyme
G3H79_RS38570	COG1902	pentaerythritol trinitrate reductase activity
G3H79_RS38600	COG2207	Transcriptional regulator
G3H79_RS38600	COG3708	Transcriptional regulator
G3H79_RS38605	COG0583	DNA-binding transcription factor activity
G3H79_RS38635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3H79_RS38665	COG0745	RESPONSE REGULATOR receiver
G3H79_RS38670	COG2205	protein histidine kinase activity
G3H79_RS38705	COG3896	Chloramphenicol phosphotransferase-like protein
G3H79_RS38730	COG0583	DNA-binding transcription factor activity
G3H79_RS38785	COG1132	(ABC) transporter
G3H79_RS38795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3H79_RS38805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3H79_RS38820	COG1595	DNA-templated transcription, initiation
G3H79_RS38890	COG2814	Major facilitator Superfamily
G3H79_RS38895	COG0640	Transcriptional regulator
G3H79_RS38925	COG0456	acetyltransferase
G3H79_RS38940	COG1733	regulation of RNA biosynthetic process
G3H79_RS38955	COG2066	Belongs to the glutaminase family
G3H79_RS38980	COG1595	DNA-templated transcription, initiation
G3H79_RS38995	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G3H79_RS39000	COG0735	belongs to the Fur family
G3H79_RS39035	COG3568	Endonuclease Exonuclease Phosphatase
G3H79_RS39045	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G3H79_RS39050	COG0584	glycerophosphoryl diester phosphodiesterase
G3H79_RS39055	COG0009	L-threonylcarbamoyladenylate synthase
G3H79_RS39065	COG2197	response regulator
G3H79_RS39075	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS39080	COG2205	protein histidine kinase activity
G3H79_RS39085	COG0745	RESPONSE REGULATOR receiver
G3H79_RS39100	COG1136	(ABC) transporter
G3H79_RS39100	COG0577	efflux transmembrane transporter activity
G3H79_RS39105	COG1136	(ABC) transporter
G3H79_RS39105	COG0577	efflux transmembrane transporter activity
G3H79_RS39135	COG0697	spore germination
G3H79_RS39140	COG0583	DNA-binding transcription factor activity
G3H79_RS39145	COG0137	argininosuccinate synthase activity
G3H79_RS39155	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3H79_RS39160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G3H79_RS39170	COG2124	cytochrome p450
G3H79_RS39190	COG3251	PFAM MbtH domain protein
G3H79_RS39250	COG2318	DinB family
G3H79_RS39270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G3H79_RS39275	COG3285	dna ligase
G3H79_RS39275	COG1793	dna ligase
G3H79_RS39335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3H79_RS39345	COG0300	oxidoreductase activity
G3H79_RS39365	COG3973	AAA domain
G3H79_RS39410	COG3647	Membrane
G3H79_RS39495	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS39500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3H79_RS39545	COG1120	ATPase activity
G3H79_RS39560	COG1733	regulation of RNA biosynthetic process
G3H79_RS39565	COG2084	Dehydrogenase
G3H79_RS39590	COG3250	beta-galactosidase activity
G3H79_RS39600	COG1879	ABC-type sugar transport system periplasmic component
G3H79_RS39610	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3H79_RS39615	COG1129	ABC transporter
G3H79_RS39620	COG4952	isomerase
G3H79_RS39625	COG3347	Dehydrogenase
G3H79_RS39625	COG1028	Short-chain dehydrogenase reductase Sdr
G3H79_RS39630	COG1070	Carbohydrate kinase
G3H79_RS39635	COG0656	L-ascorbic acid biosynthetic process
G3H79_RS39660	COG2197	response regulator
G3H79_RS39695	COG2318	DinB family
G3H79_RS39730	COG0697	spore germination
G3H79_RS39760	COG4948	Mandelate Racemase Muconate Lactonizing
G3H79_RS39770	COG0154	amidase activity
G3H79_RS39790	COG0583	DNA-binding transcription factor activity
G3H79_RS39795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G3H79_RS39820	COG0346	lactoylglutathione lyase activity
G3H79_RS39825	COG0640	Transcriptional regulator
G3H79_RS39845	COG0745	RESPONSE REGULATOR receiver
G3H79_RS39850	COG0642	Histidine kinase
G3H79_RS39875	COG0583	DNA-binding transcription factor activity
G3H79_RS39910	COG1609	Transcriptional regulator
G3H79_RS39920	COG1335	isochorismatase
G3H79_RS39925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G3H79_RS39935	COG2197	response regulator
G3H79_RS39940	COG4585	Histidine kinase
G3H79_RS39945	COG0577	efflux transmembrane transporter activity
G3H79_RS39945	COG1136	(ABC) transporter
G3H79_RS39970	COG0640	Transcriptional regulator
G3H79_RS39975	COG0798	PFAM Bile acid sodium symporter
G3H79_RS39990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3H79_RS40005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3H79_RS40015	COG1609	Transcriptional regulator
G3H79_RS40035	COG3848	Pyruvate phosphate dikinase
G3H79_RS40035	COG0574	Belongs to the PEP-utilizing enzyme family
G3H79_RS40070	COG0583	DNA-binding transcription factor activity
G3H79_RS40075	COG0300	oxidoreductase activity
G3H79_RS40135	COG0583	DNA-binding transcription factor activity
G3H79_RS40165	COG0745	RESPONSE REGULATOR receiver
G3H79_RS40170	COG2205	protein histidine kinase activity
G3H79_RS40205	COG4249	Peptidase C14 caspase catalytic subunit p20
G3H79_RS40205	COG2319	Wd-40 repeat
G3H79_RS40285	COG0445	tRNA wobble uridine modification
G3H79_RS40305	COG3629	intracellular signal transduction
G3H79_RS40330	COG2867	negative regulation of translational initiation
G3H79_RS40340	COG3629	intracellular signal transduction
G3H79_RS40350	COG1960	acyl-CoA dehydrogenase activity
G3H79_RS40355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G3H79_RS40395	COG0604	alcohol dehydrogenase
G3H79_RS40395	COG3321	synthase
G3H79_RS40405	COG0477	Major facilitator Superfamily
G3H79_RS40415	COG3629	intracellular signal transduction
G3H79_RS40420	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G3H79_RS40430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3H79_RS40450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3H79_RS40460	COG1012	belongs to the aldehyde dehydrogenase family
G3H79_RS40495	COG2814	Major facilitator Superfamily
G3H79_RS40620	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G3H79_RS40810	COG0494	nUDIX hydrolase
G3H79_RS40835	COG1595	DNA-templated transcription, initiation
G3H79_RS40845	COG0592	DNA-directed DNA polymerase activity
G3H79_RS40880	COG1192	Involved in chromosome partitioning
G3H79_RS40885	COG1475	DNA binding
G3H79_RS40920	COG0791	NLP P60 protein
G3H79_RS40920	COG3883	PFAM NLP P60 protein
G3H79_RS40975	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G3H79_RS41130	COG0587	DNA-directed DNA polymerase activity
G3H79_RS41150	COG2815	serine threonine protein kinase
G3H79_RS41150	COG0515	serine threonine protein kinase