locus-tag	class	description
DJ476_RS00050	COG0829	nickel cation binding
DJ476_RS00055	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DJ476_RS00065	COG0804	urea catabolic process
DJ476_RS00070	COG0831	urea catabolic process
DJ476_RS00070	COG0832	Belongs to the urease beta subunit family
DJ476_RS00090	COG1505	serine-type exopeptidase activity
DJ476_RS00120	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DJ476_RS00130	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DJ476_RS00135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS00185	COG2367	Beta-lactamase
DJ476_RS00210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DJ476_RS00220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DJ476_RS00225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DJ476_RS00230	COG0395	ABC-type sugar transport system, permease component
DJ476_RS00235	COG1175	transmembrane transport
DJ476_RS00270	COG2890	protein-(glutamine-N5) methyltransferase activity
DJ476_RS00280	COG1891	lyase activity
DJ476_RS00295	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DJ476_RS00315	COG0142	geranyltranstransferase activity
DJ476_RS00335	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DJ476_RS00370	COG0009	L-threonylcarbamoyladenylate synthase
DJ476_RS00385	COG0488	(ABC) transporter
DJ476_RS00415	COG2340	Cysteine-rich secretory protein family
DJ476_RS00425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DJ476_RS00430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DJ476_RS00445	COG1595	DNA-templated transcription, initiation
DJ476_RS00505	COG2018	Roadblock/LC7 domain
DJ476_RS00520	COG0640	Transcriptional regulator
DJ476_RS00525	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DJ476_RS00530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DJ476_RS00545	COG2267	carboxylic ester hydrolase activity
DJ476_RS00565	COG3239	Fatty acid desaturase
DJ476_RS00575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DJ476_RS00595	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS00610	COG3328	transposase activity
DJ476_RS00650	COG0745	RESPONSE REGULATOR receiver
DJ476_RS00680	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DJ476_RS00740	COG2223	nitrite transmembrane transporter activity
DJ476_RS00745	COG0243	molybdopterin cofactor binding
DJ476_RS00750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DJ476_RS00750	COG2146	nitrite reductase [NAD(P)H] activity
DJ476_RS00755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DJ476_RS00755	COG2146	nitrite reductase [NAD(P)H] activity
DJ476_RS00770	COG3300	MHYT domain
DJ476_RS00770	COG5001	Diguanylate cyclase
DJ476_RS00780	COG5297	Belongs to the glycosyl hydrolase family 6
DJ476_RS00820	COG4044	May play a role in the intracellular transport of hydrophobic ligands
DJ476_RS00840	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DJ476_RS00855	COG1278	Cold shock
DJ476_RS00875	COG0445	tRNA wobble uridine modification
DJ476_RS00940	COG1796	DNA polymerase
DJ476_RS00940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DJ476_RS01000	COG0444	Belongs to the ABC transporter superfamily
DJ476_RS01005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DJ476_RS01010	COG0601	transmembrane transport
DJ476_RS01025	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS01030	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS01050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DJ476_RS01060	COG1125	glycine betaine transport
DJ476_RS01060	COG0517	IMP dehydrogenase activity
DJ476_RS01080	COG1174	glycine betaine transport
DJ476_RS01085	COG1174	glycine betaine transport
DJ476_RS01125	COG0297	glycogen (starch) synthase activity
DJ476_RS01125	COG0438	transferase activity, transferring glycosyl groups
DJ476_RS01150	COG0438	transferase activity, transferring glycosyl groups
DJ476_RS01195	COG1132	(ABC) transporter
DJ476_RS01225	COG1120	ATPase activity
DJ476_RS01230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS01235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS01255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DJ476_RS01260	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DJ476_RS01265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DJ476_RS01270	COG0254	rRNA binding
DJ476_RS01280	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DJ476_RS01285	COG0477	Major facilitator Superfamily
DJ476_RS01315	COG0431	NADPH-dependent FMN reductase
DJ476_RS01340	COG0243	molybdopterin cofactor binding
DJ476_RS01360	COG0574	Belongs to the PEP-utilizing enzyme family
DJ476_RS01360	COG3848	Pyruvate phosphate dikinase
DJ476_RS01390	COG1309	transcriptional regulator
DJ476_RS01425	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS01450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DJ476_RS01465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DJ476_RS01480	COG1834	amidinotransferase
DJ476_RS01500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DJ476_RS01510	COG1609	Transcriptional regulator
DJ476_RS01530	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DJ476_RS01535	COG0121	glutamine amidotransferase
DJ476_RS01540	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DJ476_RS01560	COG3360	Dodecin
DJ476_RS01570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DJ476_RS01590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DJ476_RS01595	COG1053	succinate dehydrogenase
DJ476_RS01605	COG0583	DNA-binding transcription factor activity
DJ476_RS01680	COG3275	phosphorelay sensor kinase activity
DJ476_RS01685	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DJ476_RS01705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DJ476_RS01745	COG1191	sigma factor activity
DJ476_RS01750	COG2201	protein-glutamate methylesterase activity
DJ476_RS01755	COG4251	negative regulation of phosphorylation
DJ476_RS01760	COG0784	Response regulator, receiver
DJ476_RS01795	COG1652	LysM domain
DJ476_RS01815	COG1175	transmembrane transport
DJ476_RS01820	COG0395	ABC-type sugar transport system, permease component
DJ476_RS01830	COG0596	Alpha beta hydrolase
DJ476_RS01865	COG0789	Transcriptional regulator
DJ476_RS01875	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DJ476_RS01890	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DJ476_RS01895	COG2837	iron assimilation
DJ476_RS01905	COG0019	diaminopimelate decarboxylase activity
DJ476_RS01915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DJ476_RS01925	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DJ476_RS01940	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DJ476_RS01945	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DJ476_RS01950	COG2080	2 iron, 2 sulfur cluster binding
DJ476_RS01965	COG2124	cytochrome p450
DJ476_RS01970	COG2130	NADP-dependent
DJ476_RS01975	COG1233	COG1233 Phytoene dehydrogenase and related
DJ476_RS02010	COG4977	sequence-specific DNA binding
DJ476_RS02040	COG1846	Transcriptional regulator
DJ476_RS02060	COG0446	pyridine nucleotide-disulphide oxidoreductase
DJ476_RS02060	COG1902	pentaerythritol trinitrate reductase activity
DJ476_RS02125	COG0714	Associated with various cellular activities
DJ476_RS02145	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DJ476_RS02150	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DJ476_RS02155	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DJ476_RS02165	COG1316	TRANSCRIPTIONal
DJ476_RS02175	COG2079	MmgE PrpD family protein
DJ476_RS02205	COG3629	intracellular signal transduction
DJ476_RS02205	COG3903	Transcriptional regulator
DJ476_RS02230	COG1250	3-hydroxyacyl-CoA dehydrogenase
DJ476_RS02245	COG0604	alcohol dehydrogenase
DJ476_RS02245	COG3321	synthase
DJ476_RS02260	COG0156	8-amino-7-oxononanoate synthase activity
DJ476_RS02270	COG0318	PFAM AMP-dependent synthetase and ligase
DJ476_RS02395	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DJ476_RS02395	COG1672	PFAM Archaeal ATPase
DJ476_RS02415	COG1556	Lactate utilization protein
DJ476_RS02420	COG1139	Iron-sulfur cluster binding protein
DJ476_RS02425	COG0247	lactate metabolic process
DJ476_RS02435	COG3851	Histidine kinase
DJ476_RS02440	COG2197	response regulator
DJ476_RS02450	COG3511	phospholipase C
DJ476_RS02470	COG0318	PFAM AMP-dependent synthetase and ligase
DJ476_RS02490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DJ476_RS02505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DJ476_RS02520	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS02545	COG1215	transferase activity, transferring glycosyl groups
DJ476_RS02590	COG3959	Transketolase, thiamine diphosphate binding domain
DJ476_RS02595	COG3958	Transketolase
DJ476_RS02625	COG1116	anion transmembrane transporter activity
DJ476_RS02635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DJ476_RS02640	COG1609	Transcriptional regulator
DJ476_RS02680	COG3467	pyridoxamine 5'-phosphate
DJ476_RS02720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DJ476_RS02730	COG2755	lipolytic protein G-D-S-L family
DJ476_RS02740	COG2365	Tyrosine phosphatase family
DJ476_RS02765	COG1657	PFAM Prenyltransferase squalene oxidase
DJ476_RS02775	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DJ476_RS02785	COG1562	ergosterol biosynthetic process
DJ476_RS02790	COG1388	LysM domain
DJ476_RS02790	COG1134	teichoic acid transport
DJ476_RS02805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DJ476_RS02835	COG4106	trans-aconitate 2-methyltransferase activity
DJ476_RS02840	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DJ476_RS02855	COG1024	Enoyl-CoA hydratase
DJ476_RS02865	COG4977	sequence-specific DNA binding
DJ476_RS02875	COG2183	response to ionizing radiation
DJ476_RS02880	COG0488	(ABC) transporter
DJ476_RS02905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DJ476_RS02930	COG0789	Transcriptional regulator
DJ476_RS02935	COG1024	Enoyl-CoA hydratase
DJ476_RS02935	COG1250	3-hydroxyacyl-CoA dehydrogenase
DJ476_RS02940	COG0183	Belongs to the thiolase family
DJ476_RS02945	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS02950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DJ476_RS02955	COG3268	Saccharopine dehydrogenase
DJ476_RS02965	COG1515	deoxyribonuclease V activity
DJ476_RS02980	COG0488	(ABC) transporter
DJ476_RS02985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DJ476_RS03025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DJ476_RS03060	COG1793	dna ligase
DJ476_RS03080	COG2208	phosphoserine phosphatase activity
DJ476_RS03080	COG2770	Histidine kinase
DJ476_RS03115	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DJ476_RS03140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DJ476_RS03195	COG3012	SEC-C Motif Domain Protein
DJ476_RS03235	COG1486	melibiose metabolic process
DJ476_RS03270	COG1846	Transcriptional regulator
DJ476_RS03295	COG1940	carbohydrate kinase activity
DJ476_RS03305	COG1070	Carbohydrate kinase
DJ476_RS03320	COG2985	domain, Protein
DJ476_RS03320	COG0569	domain protein
DJ476_RS03325	COG2124	cytochrome p450
DJ476_RS03335	COG4176	ABC-type proline glycine betaine transport system permease component
DJ476_RS03340	COG4175	Glycine betaine
DJ476_RS03340	COG0517	IMP dehydrogenase activity
DJ476_RS03350	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS03380	COG0745	RESPONSE REGULATOR receiver
DJ476_RS03385	COG5002	protein histidine kinase activity
DJ476_RS03415	COG0714	Associated with various cellular activities
DJ476_RS03430	COG1869	D-ribose catabolic process
DJ476_RS03435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DJ476_RS03445	COG1129	ABC transporter
DJ476_RS03455	COG3559	Exporter of polyketide antibiotics
DJ476_RS03460	COG1131	(ABC) transporter
DJ476_RS03470	COG0569	domain protein
DJ476_RS03475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DJ476_RS03520	COG2208	phosphoserine phosphatase activity
DJ476_RS03520	COG2770	Histidine kinase
DJ476_RS03535	COG0589	response to stress
DJ476_RS03555	COG1881	PFAM PEBP family protein
DJ476_RS03565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DJ476_RS03640	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DJ476_RS03660	COG0673	inositol 2-dehydrogenase activity
DJ476_RS03670	COG1172	Belongs to the binding-protein-dependent transport system permease family
DJ476_RS03675	COG1129	ABC transporter
DJ476_RS03685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DJ476_RS03690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DJ476_RS03715	COG0656	L-ascorbic acid biosynthetic process
DJ476_RS03725	COG4106	trans-aconitate 2-methyltransferase activity
DJ476_RS03735	COG0702	epimerase
DJ476_RS03745	COG2154	pterin-4-alpha-carbinolamine dehydratase
DJ476_RS03755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DJ476_RS03755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DJ476_RS03770	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DJ476_RS03795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DJ476_RS03815	COG2226	methyltransferase
DJ476_RS03835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DJ476_RS03850	COG1619	proteins homologs of microcin C7 resistance protein MccF
DJ476_RS03860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DJ476_RS03865	COG2362	D-Aminopeptidase
DJ476_RS03875	COG0667	Aldo Keto reductase
DJ476_RS03880	COG0583	DNA-binding transcription factor activity
DJ476_RS03915	COG1250	3-hydroxyacyl-CoA dehydrogenase
DJ476_RS03930	COG0456	acetyltransferase
DJ476_RS03935	COG0604	alcohol dehydrogenase
DJ476_RS03940	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DJ476_RS03940	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DJ476_RS03945	COG2301	Belongs to the HpcH HpaI aldolase family
DJ476_RS03955	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS03960	COG0688	phosphatidylethanolamine metabolic process
DJ476_RS03990	COG0559	Belongs to the binding-protein-dependent transport system permease family
DJ476_RS03995	COG0559	Belongs to the binding-protein-dependent transport system permease family
DJ476_RS04015	COG1929	Belongs to the glycerate kinase type-1 family
DJ476_RS04030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DJ476_RS04045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DJ476_RS04080	COG1024	Enoyl-CoA hydratase
DJ476_RS04085	COG1131	(ABC) transporter
DJ476_RS04095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DJ476_RS04105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DJ476_RS04110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DJ476_RS04115	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS04150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DJ476_RS04155	COG1024	Enoyl-CoA hydratase
DJ476_RS04195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DJ476_RS04210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DJ476_RS04235	COG1024	Enoyl-CoA hydratase
DJ476_RS04250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DJ476_RS04255	COG0095	Lipoate-protein ligase
DJ476_RS04265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DJ476_RS04275	COG2838	Isocitrate dehydrogenase
DJ476_RS04325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DJ476_RS04330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DJ476_RS04340	COG0667	Aldo Keto reductase
DJ476_RS04370	COG0405	Gamma-glutamyltransferase
DJ476_RS04410	COG1376	ErfK ybiS ycfS ynhG family protein
DJ476_RS04420	COG0765	amino acid transport
DJ476_RS04425	COG0765	amino acid transport
DJ476_RS04430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DJ476_RS04435	COG1126	abc transporter atp-binding protein
DJ476_RS04470	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DJ476_RS04475	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DJ476_RS04485	COG1940	carbohydrate kinase activity
DJ476_RS04490	COG1129	ABC transporter
DJ476_RS04505	COG2188	Transcriptional regulator
DJ476_RS04510	COG0673	inositol 2-dehydrogenase activity
DJ476_RS04555	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS04560	COG0656	L-ascorbic acid biosynthetic process
DJ476_RS04570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DJ476_RS04575	COG1414	Transcriptional regulator
DJ476_RS04595	COG2197	response regulator
DJ476_RS04610	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DJ476_RS04655	COG2233	PERMEase
DJ476_RS04665	COG2233	PERMEase
DJ476_RS04675	COG2351	hydroxyisourate hydrolase activity
DJ476_RS04705	COG0395	ABC-type sugar transport system, permease component
DJ476_RS04715	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DJ476_RS04725	COG3622	Belongs to the hyi family
DJ476_RS04730	COG2084	Dehydrogenase
DJ476_RS04735	COG0753	catalase activity
DJ476_RS04750	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DJ476_RS04765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DJ476_RS04775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DJ476_RS04785	COG3629	intracellular signal transduction
DJ476_RS04785	COG3903	Transcriptional regulator
DJ476_RS04800	COG3960	tartronate-semialdehyde synthase activity
DJ476_RS04820	COG0318	PFAM AMP-dependent synthetase and ligase
DJ476_RS04825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DJ476_RS04830	COG2197	response regulator
DJ476_RS04840	COG0435	Glutathione S-transferase
DJ476_RS04870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DJ476_RS04900	COG3608	succinylglutamate desuccinylase aspartoacylase
DJ476_RS04900	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DJ476_RS04905	COG2252	PERMEase
DJ476_RS04910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DJ476_RS04935	COG1802	Transcriptional regulator
DJ476_RS04955	COG0028	Belongs to the TPP enzyme family
DJ476_RS04985	COG1162	GTPase activity
DJ476_RS05035	COG0183	Belongs to the thiolase family
DJ476_RS05040	COG0583	DNA-binding transcription factor activity
DJ476_RS05045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DJ476_RS05050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DJ476_RS05055	COG1250	3-hydroxyacyl-CoA dehydrogenase
DJ476_RS05075	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS05100	COG0175	sulfate reduction
DJ476_RS05105	COG0529	Catalyzes the synthesis of activated sulfate
DJ476_RS05125	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DJ476_RS05130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DJ476_RS05140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DJ476_RS05150	COG1132	(ABC) transporter
DJ476_RS05155	COG1132	(ABC) transporter
DJ476_RS05170	COG1404	Belongs to the peptidase S8 family
DJ476_RS05190	COG1175	transmembrane transport
DJ476_RS05250	COG2723	6-phospho-beta-galactosidase activity
DJ476_RS05265	COG1072	(Pantothenic acid kinase))
DJ476_RS05270	COG0346	lactoylglutathione lyase activity
DJ476_RS05280	COG0583	DNA-binding transcription factor activity
DJ476_RS05285	COG0156	8-amino-7-oxononanoate synthase activity
DJ476_RS05290	COG1063	alcohol dehydrogenase
DJ476_RS05320	COG1100	Small GTP-binding protein
DJ476_RS05355	COG0483	inositol monophosphate 1-phosphatase activity
DJ476_RS05395	COG0513	Belongs to the DEAD box helicase family
DJ476_RS05440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DJ476_RS05445	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DJ476_RS05505	COG3220	belongs to the UPF0276 family
DJ476_RS05520	COG3253	May function as heme-dependent peroxidase
DJ476_RS05525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DJ476_RS05535	COG0446	pyridine nucleotide-disulphide oxidoreductase
DJ476_RS05540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DJ476_RS05560	COG0183	Belongs to the thiolase family
DJ476_RS05565	COG1024	Enoyl-CoA hydratase
DJ476_RS05565	COG1250	3-hydroxyacyl-CoA dehydrogenase
DJ476_RS05570	COG1316	TRANSCRIPTIONal
DJ476_RS05585	COG0531	amino acid
DJ476_RS05590	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DJ476_RS05595	COG4214	carbohydrate transport
DJ476_RS05605	COG4213	ABC transporter substrate-binding protein
DJ476_RS05610	COG1940	carbohydrate kinase activity
DJ476_RS05615	COG0395	ABC-type sugar transport system, permease component
DJ476_RS05620	COG1175	transmembrane transport
DJ476_RS05625	COG1653	transport
DJ476_RS05635	COG0406	alpha-ribazole phosphatase activity
DJ476_RS05665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DJ476_RS05675	COG2267	carboxylic ester hydrolase activity
DJ476_RS05680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DJ476_RS05690	COG2801	Transposase and inactivated derivatives
DJ476_RS05725	COG3458	cephalosporin-C deacetylase activity
DJ476_RS05745	COG1482	cell wall glycoprotein biosynthetic process
DJ476_RS05760	COG1609	Transcriptional regulator
DJ476_RS05775	COG1175	transmembrane transport
DJ476_RS05780	COG3833	ABC-type maltose transport systems, permease component
DJ476_RS05790	COG0515	serine threonine protein kinase
DJ476_RS05815	COG3629	intracellular signal transduction
DJ476_RS05815	COG3903	Transcriptional regulator
DJ476_RS05830	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS05865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DJ476_RS05870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DJ476_RS05875	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DJ476_RS05910	COG0489	protein tyrosine kinase activity
DJ476_RS05915	COG0297	glycogen (starch) synthase activity
DJ476_RS05930	COG1320	monovalent cation:proton antiporter activity
DJ476_RS05945	COG0651	ATP synthesis coupled electron transport
DJ476_RS05950	COG1006	Multisubunit Na H antiporter MnhC subunit
DJ476_RS05980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DJ476_RS06000	COG1024	Enoyl-CoA hydratase
DJ476_RS06010	COG0531	amino acid
DJ476_RS06015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DJ476_RS06025	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DJ476_RS06035	COG2040	homocysteine
DJ476_RS06055	COG1799	cell septum assembly
DJ476_RS06060	COG1349	DNA-binding transcription factor activity
DJ476_RS06120	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS06125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS06150	COG3835	regulator
DJ476_RS06155	COG1802	Transcriptional regulator
DJ476_RS06160	COG3938	Belongs to the proline racemase family
DJ476_RS06180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DJ476_RS06185	COG3291	Pkd domain containing protein
DJ476_RS06215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DJ476_RS06220	COG1280	lysine exporter protein (LysE YggA)
DJ476_RS06225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DJ476_RS06230	COG0505	Belongs to the CarA family
DJ476_RS06255	COG2192	nodulation
DJ476_RS06350	COG1674	ftsk spoiiie
DJ476_RS06360	COG0464	growth
DJ476_RS06385	COG0596	Alpha beta hydrolase
DJ476_RS06405	COG4585	Histidine kinase
DJ476_RS06410	COG3629	intracellular signal transduction
DJ476_RS06410	COG3903	Transcriptional regulator
DJ476_RS06450	COG0515	serine threonine protein kinase
DJ476_RS06450	COG2815	serine threonine protein kinase
DJ476_RS06510	COG0210	DNA helicase
DJ476_RS06520	COG1401	restriction endodeoxyribonuclease activity
DJ476_RS06535	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DJ476_RS06555	COG2442	InterPro IPR007367
DJ476_RS06590	COG0443	Heat shock 70 kDa protein
DJ476_RS06605	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DJ476_RS06615	COG2815	serine threonine protein kinase
DJ476_RS06615	COG0515	serine threonine protein kinase
DJ476_RS06635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DJ476_RS06640	COG0531	amino acid
DJ476_RS06645	COG0569	domain protein
DJ476_RS06680	COG0756	dUTP diphosphatase activity
DJ476_RS06705	COG2205	protein histidine kinase activity
DJ476_RS06710	COG0745	RESPONSE REGULATOR receiver
DJ476_RS06720	COG0483	inositol monophosphate 1-phosphatase activity
DJ476_RS06725	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DJ476_RS06760	COG1435	thymidine kinase activity
DJ476_RS06775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DJ476_RS06775	COG1042	CoA-binding domain protein
DJ476_RS06775	COG0045	succinate-CoA ligase (ADP-forming) activity
DJ476_RS06780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DJ476_RS06785	COG1802	Transcriptional regulator
DJ476_RS06800	COG0612	Peptidase, M16
DJ476_RS06805	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DJ476_RS06815	COG0372	Belongs to the citrate synthase family
DJ476_RS06830	COG3290	protein histidine kinase activity
DJ476_RS06835	COG4565	transcriptional regulatory protein
DJ476_RS06840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DJ476_RS06865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DJ476_RS06875	COG2186	Transcriptional regulator
DJ476_RS06880	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DJ476_RS06895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DJ476_RS06900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DJ476_RS06935	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DJ476_RS07015	COG0596	Alpha beta hydrolase
DJ476_RS07025	COG2197	response regulator
DJ476_RS07065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DJ476_RS07070	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DJ476_RS07075	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DJ476_RS07115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DJ476_RS07125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DJ476_RS07130	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DJ476_RS07150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DJ476_RS07165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DJ476_RS07170	COG2358	TRAP transporter, solute receptor (TAXI family
DJ476_RS07175	COG2205	protein histidine kinase activity
DJ476_RS07180	COG0745	RESPONSE REGULATOR receiver
DJ476_RS07185	COG1126	abc transporter atp-binding protein
DJ476_RS07190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DJ476_RS07195	COG0765	amino acid transport
DJ476_RS07200	COG0765	amino acid transport
DJ476_RS07215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DJ476_RS07230	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DJ476_RS07235	COG0640	Transcriptional regulator
DJ476_RS07250	COG1672	PFAM Archaeal ATPase
DJ476_RS07250	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DJ476_RS07260	COG4585	Histidine kinase
DJ476_RS07265	COG2197	response regulator
DJ476_RS07305	COG2207	Transcriptional regulator
DJ476_RS07305	COG1917	Cupin 2, conserved barrel domain protein
DJ476_RS07310	COG1201	RNA secondary structure unwinding
DJ476_RS07320	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS07335	COG0783	Belongs to the Dps family
DJ476_RS07340	COG1396	sequence-specific DNA binding
DJ476_RS07345	COG1546	Belongs to the CinA family
DJ476_RS07345	COG1058	Belongs to the CinA family
DJ476_RS07355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DJ476_RS07365	COG1674	ftsk spoiiie
DJ476_RS07380	COG2770	Histidine kinase
DJ476_RS07380	COG2208	phosphoserine phosphatase activity
DJ476_RS07410	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DJ476_RS07415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DJ476_RS07420	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DJ476_RS07440	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DJ476_RS07445	COG0612	Peptidase, M16
DJ476_RS07450	COG1185	polyribonucleotide nucleotidyltransferase activity
DJ476_RS07455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DJ476_RS07465	COG1674	ftsk spoiiie
DJ476_RS07480	COG1404	Belongs to the peptidase S8 family
DJ476_RS07480	COG4935	Belongs to the peptidase S8 family
DJ476_RS07495	COG1404	Belongs to the peptidase S8 family
DJ476_RS07500	COG3266	domain, Protein
DJ476_RS07520	COG0455	bacterial-type flagellum organization
DJ476_RS07525	COG0747	negative chemotaxis
DJ476_RS07530	COG0601	transmembrane transport
DJ476_RS07535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DJ476_RS07565	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DJ476_RS07570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DJ476_RS07580	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DJ476_RS07595	COG0779	Required for maturation of 30S ribosomal subunits
DJ476_RS07615	COG0442	prolyl-tRNA aminoacylation
DJ476_RS07630	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DJ476_RS07635	COG0750	zinc metalloprotease
DJ476_RS07640	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DJ476_RS07665	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS07670	COG2508	Transcriptional regulator
DJ476_RS07705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DJ476_RS07710	COG1177	transmembrane transport
DJ476_RS07715	COG1176	ABC-type spermidine putrescine transport system, permease component I
DJ476_RS07720	COG3842	ATPase activity
DJ476_RS07725	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DJ476_RS07745	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DJ476_RS07770	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS07780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DJ476_RS07785	COG1136	(ABC) transporter
DJ476_RS07800	COG3842	ATPase activity
DJ476_RS07815	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DJ476_RS07825	COG0233	cytoplasmic translational termination
DJ476_RS07830	COG0528	UMP kinase activity
DJ476_RS07835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DJ476_RS07840	COG0052	Belongs to the universal ribosomal protein uS2 family
DJ476_RS07855	COG1191	sigma factor activity
DJ476_RS07870	COG0792	nuclease activity
DJ476_RS07885	COG0681	Belongs to the peptidase S26 family
DJ476_RS07890	COG0681	Belongs to the peptidase S26 family
DJ476_RS07905	COG0335	large ribosomal subunit rRNA binding
DJ476_RS07910	COG0336	Belongs to the RNA methyltransferase TrmD family
DJ476_RS07915	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DJ476_RS07920	COG1837	Belongs to the UPF0109 family
DJ476_RS07925	COG0228	four-way junction DNA binding
DJ476_RS07945	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DJ476_RS07980	COG0477	Major facilitator Superfamily
DJ476_RS07985	COG1196	nuclear chromosome segregation
DJ476_RS08000	COG1254	Belongs to the acylphosphatase family
DJ476_RS08005	COG2340	Cysteine-rich secretory protein family
DJ476_RS08010	COG1733	regulation of RNA biosynthetic process
DJ476_RS08015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DJ476_RS08020	COG0571	ribonuclease III activity
DJ476_RS08025	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DJ476_RS08040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DJ476_RS08045	COG0742	ribosomal rna small subunit methyltransferase
DJ476_RS08050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DJ476_RS08055	COG1461	Dihydroxyacetone kinase
DJ476_RS08060	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DJ476_RS08065	COG0351	phosphomethylpyrimidine kinase
DJ476_RS08080	COG1181	Belongs to the D-alanine--D-alanine ligase family
DJ476_RS08085	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DJ476_RS08095	COG1920	GTP binding
DJ476_RS08105	COG0776	regulation of translation
DJ476_RS08115	COG0066	3-isopropylmalate dehydratase activity
DJ476_RS08120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DJ476_RS08125	COG1414	Transcriptional regulator
DJ476_RS08160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DJ476_RS08165	COG0179	Fumarylacetoacetate (FAA) hydrolase
DJ476_RS08175	COG5002	protein histidine kinase activity
DJ476_RS08180	COG2018	Roadblock/LC7 domain
DJ476_RS08200	COG2018	Roadblock/LC7 domain
DJ476_RS08220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DJ476_RS08225	COG1470	cell adhesion involved in biofilm formation
DJ476_RS08225	COG0366	Alpha amylase catalytic
DJ476_RS08250	COG4607	ABC-type enterochelin transport system periplasmic component
DJ476_RS08255	COG1120	ATPase activity
DJ476_RS08260	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS08265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS08290	COG1733	regulation of RNA biosynthetic process
DJ476_RS08315	COG0492	ferredoxin-NADP+ reductase activity
DJ476_RS08340	COG2207	Transcriptional regulator
DJ476_RS08340	COG3708	Transcriptional regulator
DJ476_RS08355	COG1472	Belongs to the glycosyl hydrolase 3 family
DJ476_RS08365	COG0444	Belongs to the ABC transporter superfamily
DJ476_RS08370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DJ476_RS08375	COG0601	transmembrane transport
DJ476_RS08380	COG4608	Belongs to the ABC transporter superfamily
DJ476_RS08390	COG1609	Transcriptional regulator
DJ476_RS08395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DJ476_RS08405	COG2957	Belongs to the agmatine deiminase family
DJ476_RS08410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DJ476_RS08415	COG0473	3-isopropylmalate dehydrogenase activity
DJ476_RS08425	COG2130	NADP-dependent
DJ476_RS08440	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS08445	COG0506	proline dehydrogenase activity
DJ476_RS08475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DJ476_RS08480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DJ476_RS08485	COG0440	acetolactate synthase activity
DJ476_RS08505	COG0667	Aldo Keto reductase
DJ476_RS08510	COG2133	pyrroloquinoline quinone binding
DJ476_RS08525	COG2409	Drug exporters of the RND superfamily
DJ476_RS08535	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DJ476_RS08540	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DJ476_RS08550	COG0154	amidase activity
DJ476_RS08555	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DJ476_RS08565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DJ476_RS08575	COG4221	oxidoreductase activity
DJ476_RS08595	COG0482	sulfurtransferase activity
DJ476_RS08625	COG2860	membrane
DJ476_RS08630	COG4608	Belongs to the ABC transporter superfamily
DJ476_RS08640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DJ476_RS08645	COG0601	transmembrane transport
DJ476_RS08650	COG4166	transmembrane transport
DJ476_RS08670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DJ476_RS08675	COG0509	glycine decarboxylation via glycine cleavage system
DJ476_RS08680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DJ476_RS08685	COG1760	l-serine dehydratase
DJ476_RS08755	COG2235	arginine
DJ476_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS08805	COG0823	Involved in the tonB-independent uptake of proteins
DJ476_RS08945	COG2197	response regulator
DJ476_RS08960	COG1131	(ABC) transporter
DJ476_RS08965	COG1132	(ABC) transporter
DJ476_RS08970	COG1132	(ABC) transporter
DJ476_RS08995	COG0058	SHG alpha-glucan phosphorylase activity
DJ476_RS09000	COG0366	Alpha amylase catalytic
DJ476_RS09005	COG0366	Alpha amylase catalytic
DJ476_RS09010	COG3281	Trehalose synthase
DJ476_RS09015	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DJ476_RS09020	COG1301	dicarboxylic acid transport
DJ476_RS09025	COG3290	protein histidine kinase activity
DJ476_RS09030	COG4565	transcriptional regulatory protein
DJ476_RS09040	COG0205	6-phosphofructokinase activity
DJ476_RS09045	COG0280	phosphate acetyltransferase
DJ476_RS09045	COG0857	belongs to the CobB CobQ family
DJ476_RS09050	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DJ476_RS09090	COG1597	lipid kinase activity
DJ476_RS09095	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DJ476_RS09095	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DJ476_RS09170	COG5002	protein histidine kinase activity
DJ476_RS09200	COG0183	Belongs to the thiolase family
DJ476_RS09255	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DJ476_RS09270	COG1250	3-hydroxyacyl-CoA dehydrogenase
DJ476_RS09285	COG3850	Histidine kinase
DJ476_RS09290	COG2197	response regulator
DJ476_RS09305	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DJ476_RS09310	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DJ476_RS09315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DJ476_RS09320	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DJ476_RS09325	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DJ476_RS09330	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DJ476_RS09335	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DJ476_RS09350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DJ476_RS09355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DJ476_RS09360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DJ476_RS09370	COG2890	protein-(glutamine-N5) methyltransferase activity
DJ476_RS09375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DJ476_RS09380	COG0254	rRNA binding
DJ476_RS09385	COG1316	TRANSCRIPTIONal
DJ476_RS09395	COG0083	homoserine kinase activity
DJ476_RS09400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DJ476_RS09405	COG0460	homoserine dehydrogenase
DJ476_RS09410	COG0019	diaminopimelate decarboxylase activity
DJ476_RS09415	COG0018	arginyl-trna synthetase
DJ476_RS09480	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DJ476_RS09485	COG3285	dna ligase
DJ476_RS09485	COG1793	dna ligase
DJ476_RS09505	COG2205	protein histidine kinase activity
DJ476_RS09520	COG0768	penicillin binding
DJ476_RS09550	COG1309	transcriptional regulator
DJ476_RS09565	COG0791	NLP P60 protein
DJ476_RS09565	COG3883	PFAM NLP P60 protein
DJ476_RS09610	COG0726	polysaccharide deacetylase
DJ476_RS09615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DJ476_RS09640	COG0745	RESPONSE REGULATOR receiver
DJ476_RS09645	COG2205	protein histidine kinase activity
DJ476_RS09655	COG0508	dehydrogenase complex catalyzes the overall conversion of
DJ476_RS09655	COG0567	Dehydrogenase, E1 component
DJ476_RS09680	COG0542	response to heat
DJ476_RS09700	COG0604	alcohol dehydrogenase
DJ476_RS09705	COG0281	malic enzyme
DJ476_RS09710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DJ476_RS09715	COG0765	amino acid transport
DJ476_RS09720	COG1126	abc transporter atp-binding protein
DJ476_RS09725	COG4106	trans-aconitate 2-methyltransferase activity
DJ476_RS09810	COG3328	transposase activity
DJ476_RS09835	COG0142	geranyltranstransferase activity
DJ476_RS09840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DJ476_RS09845	COG1959	2 iron, 2 sulfur cluster binding
DJ476_RS09915	COG2172	sigma factor antagonist activity
DJ476_RS09930	COG1597	lipid kinase activity
DJ476_RS09945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DJ476_RS09950	COG0363	glucosamine-6-phosphate deaminase activity
DJ476_RS09955	COG1472	Belongs to the glycosyl hydrolase 3 family
DJ476_RS09960	COG0395	ABC-type sugar transport system, permease component
DJ476_RS09965	COG1175	transmembrane transport
DJ476_RS09970	COG2182	Extracellular solute-binding protein
DJ476_RS09980	COG1966	Carbon starvation protein
DJ476_RS10010	COG1131	(ABC) transporter
DJ476_RS10030	COG2188	Transcriptional regulator
DJ476_RS10080	COG0242	peptide deformylase activity
DJ476_RS10090	COG5662	AntiSigma factor
DJ476_RS10095	COG1595	DNA-templated transcription, initiation
DJ476_RS10105	COG2135	peptidase activity
DJ476_RS10115	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DJ476_RS10120	COG1162	GTPase activity
DJ476_RS10125	COG2076	Multidrug Resistance protein
DJ476_RS10135	COG0483	inositol monophosphate 1-phosphatase activity
DJ476_RS10145	COG0753	catalase activity
DJ476_RS10170	COG1615	UPF0182 protein
DJ476_RS10180	COG3480	Lon protease (S16) C-terminal proteolytic domain
DJ476_RS10230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DJ476_RS10275	COG0210	DNA helicase
DJ476_RS10335	COG0601	transmembrane transport
DJ476_RS10340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DJ476_RS10345	COG0747	negative chemotaxis
DJ476_RS10385	COG0513	Belongs to the DEAD box helicase family
DJ476_RS10390	COG2267	carboxylic ester hydrolase activity
DJ476_RS10410	COG3415	Transposase
DJ476_RS10410	COG2801	Transposase and inactivated derivatives
DJ476_RS10415	COG1432	Conserved Protein
DJ476_RS10420	COG2095	MarC family integral membrane protein
DJ476_RS10425	COG0613	PHP domain protein
DJ476_RS10440	COG0598	Magnesium transport protein CorA
DJ476_RS10475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DJ476_RS10480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DJ476_RS10490	COG1595	DNA-templated transcription, initiation
DJ476_RS10505	COG1024	Enoyl-CoA hydratase
DJ476_RS10510	COG0519	Catalyzes the synthesis of GMP from XMP
DJ476_RS10520	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DJ476_RS10525	COG1611	Belongs to the LOG family
DJ476_RS10530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DJ476_RS10560	COG2912	Transglutaminase-like superfamily
DJ476_RS10565	COG2197	response regulator
DJ476_RS10570	COG1132	(ABC) transporter
DJ476_RS10575	COG1132	(ABC) transporter
DJ476_RS10585	COG0515	serine threonine protein kinase
DJ476_RS10600	COG0110	maltose O-acetyltransferase activity
DJ476_RS10630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DJ476_RS10660	COG1136	(ABC) transporter
DJ476_RS10660	COG0577	efflux transmembrane transporter activity
DJ476_RS10675	COG2197	response regulator
DJ476_RS10680	COG4608	Belongs to the ABC transporter superfamily
DJ476_RS10690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DJ476_RS10695	COG0601	transmembrane transport
DJ476_RS10700	COG4166	transmembrane transport
DJ476_RS10705	COG4608	Belongs to the ABC transporter superfamily
DJ476_RS10715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DJ476_RS10720	COG0601	transmembrane transport
DJ476_RS10725	COG0747	negative chemotaxis
DJ476_RS10735	COG1217	gtp-binding protein TYPA
DJ476_RS10750	COG2226	methyltransferase
DJ476_RS10755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DJ476_RS10785	COG0148	phosphopyruvate hydratase activity
DJ476_RS10820	COG3795	YCII-related domain
DJ476_RS10835	COG0463	Glycosyl transferase, family 2
DJ476_RS10845	COG1842	Phage shock protein A
DJ476_RS10915	COG0012	GTP binding
DJ476_RS10930	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DJ476_RS10940	COG1570	exodeoxyribonuclease VII activity
DJ476_RS10945	COG1722	exodeoxyribonuclease VII activity
DJ476_RS10950	COG0778	Nitroreductase
DJ476_RS10975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DJ476_RS10975	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DJ476_RS10980	COG1362	aminopeptidase activity
DJ476_RS10990	COG0114	fumarate hydratase activity
DJ476_RS11005	COG4499	WXG100 protein secretion system (Wss), protein YukC
DJ476_RS11005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DJ476_RS11025	COG1136	(ABC) transporter
DJ476_RS11040	COG0450	alkyl hydroperoxide reductase
DJ476_RS11045	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DJ476_RS11060	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DJ476_RS11065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DJ476_RS11070	COG0667	Aldo Keto reductase
DJ476_RS11120	COG2885	chlorophyll binding
DJ476_RS11140	COG2197	response regulator
DJ476_RS11145	COG3920	Histidine kinase
DJ476_RS11175	COG2894	cell division
DJ476_RS11200	COG2610	gluconate transmembrane transporter activity
DJ476_RS11205	COG0251	oxidation-reduction process
DJ476_RS11210	COG1414	Transcriptional regulator
DJ476_RS11225	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DJ476_RS11270	COG1674	ftsk spoiiie
DJ476_RS11280	COG2188	Transcriptional regulator
DJ476_RS11365	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DJ476_RS11375	COG1331	Highly conserved protein containing a thioredoxin domain
DJ476_RS11385	COG1331	Highly conserved protein containing a thioredoxin domain
DJ476_RS11390	COG0515	serine threonine protein kinase
DJ476_RS11390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DJ476_RS11420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DJ476_RS11435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DJ476_RS11440	COG2255	four-way junction helicase activity
DJ476_RS11445	COG1595	DNA-templated transcription, initiation
DJ476_RS11465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DJ476_RS11480	COG1396	sequence-specific DNA binding
DJ476_RS11485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DJ476_RS11505	COG1376	ErfK ybiS ycfS ynhG family protein
DJ476_RS11530	COG1024	Enoyl-CoA hydratase
DJ476_RS11545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DJ476_RS11555	COG0424	maF-like protein
DJ476_RS11565	COG4770	biotin carboxylase activity
DJ476_RS11575	COG1349	DNA-binding transcription factor activity
DJ476_RS11600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DJ476_RS11615	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS11620	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS11650	COG1595	DNA-templated transcription, initiation
DJ476_RS11655	COG0745	RESPONSE REGULATOR receiver
DJ476_RS11660	COG2205	protein histidine kinase activity
DJ476_RS11685	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DJ476_RS11700	COG0583	DNA-binding transcription factor activity
DJ476_RS11705	COG2814	Major facilitator Superfamily
DJ476_RS11725	COG1404	Belongs to the peptidase S8 family
DJ476_RS11745	COG1079	Belongs to the binding-protein-dependent transport system permease family
DJ476_RS11750	COG4603	Belongs to the binding-protein-dependent transport system permease family
DJ476_RS11755	COG3845	ABC transporter
DJ476_RS11760	COG1744	ABC transporter substrate-binding protein PnrA-like
DJ476_RS11765	COG1473	amidohydrolase
DJ476_RS11765	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DJ476_RS11775	COG2089	acid synthase
DJ476_RS11780	COG1083	cytidylyl-transferase
DJ476_RS11790	COG1216	Glycosyl transferase, family 2
DJ476_RS11800	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DJ476_RS11845	COG1595	DNA-templated transcription, initiation
DJ476_RS11850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DJ476_RS11900	COG2009	succinate dehydrogenase
DJ476_RS11915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DJ476_RS11945	COG1408	metallophosphoesterase
DJ476_RS11955	COG1686	Belongs to the peptidase S11 family
DJ476_RS11960	COG1295	ribonuclease BN
DJ476_RS11980	COG0180	Tryptophanyl-tRNA synthetase
DJ476_RS11985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DJ476_RS11990	COG0754	glutathionylspermidine amidase activity
DJ476_RS12000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DJ476_RS12005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DJ476_RS12010	COG0039	L-malate dehydrogenase activity
DJ476_RS12025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DJ476_RS12040	COG0138	bifunctional purine biosynthesis protein purh
DJ476_RS12070	COG0045	succinate-CoA ligase (ADP-forming) activity
DJ476_RS12075	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DJ476_RS12080	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DJ476_RS12085	COG0714	Associated with various cellular activities
DJ476_RS12110	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DJ476_RS12110	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DJ476_RS12145	COG2197	response regulator
DJ476_RS12185	COG0519	Catalyzes the synthesis of GMP from XMP
DJ476_RS12185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DJ476_RS12205	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS12210	COG0515	serine threonine protein kinase
DJ476_RS12225	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DJ476_RS12240	COG0516	GMP reductase activity
DJ476_RS12255	COG1595	DNA-templated transcription, initiation
DJ476_RS12270	COG0583	DNA-binding transcription factor activity
DJ476_RS12280	COG4221	oxidoreductase activity
DJ476_RS12290	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DJ476_RS12295	COG0726	polysaccharide deacetylase
DJ476_RS12330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DJ476_RS12355	COG0802	atpase or kinase
DJ476_RS12370	COG3189	MarR family transcriptional regulator
DJ476_RS12385	COG0736	holo-[acyl-carrier-protein] synthase activity
DJ476_RS12390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DJ476_RS12405	COG4941	Belongs to the sigma-70 factor family
DJ476_RS12410	COG3795	YCII-related domain
DJ476_RS12415	COG0747	negative chemotaxis
DJ476_RS12425	COG4566	intracellular signal transduction
DJ476_RS12440	COG1072	(Pantothenic acid kinase))
DJ476_RS12450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DJ476_RS12455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DJ476_RS12460	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DJ476_RS12465	COG0488	(ABC) transporter
DJ476_RS12475	COG0101	tRNA pseudouridine synthase activity
DJ476_RS12480	COG0203	ribosomal protein L17
DJ476_RS12485	COG0202	RNA polymerase activity
DJ476_RS12490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DJ476_RS12495	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DJ476_RS12500	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DJ476_RS12505	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DJ476_RS12515	COG0563	adenylate kinase activity
DJ476_RS12525	COG0200	Binds to the 23S rRNA
DJ476_RS12530	COG1841	ribosomal large subunit assembly
DJ476_RS12535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DJ476_RS12540	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DJ476_RS12545	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DJ476_RS12550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DJ476_RS12560	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DJ476_RS12565	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DJ476_RS12570	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DJ476_RS12575	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DJ476_RS12580	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DJ476_RS12585	COG0255	Belongs to the universal ribosomal protein uL29 family
DJ476_RS12590	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DJ476_RS12595	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DJ476_RS12600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DJ476_RS12605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DJ476_RS12610	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DJ476_RS12615	COG0089	rRNA binding
DJ476_RS12620	COG0088	Forms part of the polypeptide exit tunnel
DJ476_RS12625	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DJ476_RS12630	COG0051	transcription antitermination factor activity, RNA binding
DJ476_RS12655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DJ476_RS12660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DJ476_RS12665	COG0049	tRNA binding
DJ476_RS12670	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DJ476_RS12780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DJ476_RS12785	COG0085	RNA polymerase activity
DJ476_RS12795	COG0222	ribosome binding
DJ476_RS12800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DJ476_RS12810	COG0081	regulation of translation
DJ476_RS12815	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DJ476_RS12835	COG0436	Aminotransferase
DJ476_RS12840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DJ476_RS12855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DJ476_RS12865	COG2030	dehydratase
DJ476_RS12870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DJ476_RS12900	COG1666	GTP binding
DJ476_RS12905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DJ476_RS12915	COG2261	transglycosylase associated protein
DJ476_RS12920	COG3304	Inner membrane component domain
DJ476_RS12925	COG0501	Belongs to the peptidase M48B family
DJ476_RS12930	COG1970	mechanosensitive ion channel activity
DJ476_RS12935	COG1007	ATP synthesis coupled electron transport
DJ476_RS12945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DJ476_RS12950	COG0713	ATP synthesis coupled electron transport
DJ476_RS12955	COG0839	Belongs to the complex I subunit 6 family
DJ476_RS12960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DJ476_RS12965	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DJ476_RS12975	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DJ476_RS12980	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DJ476_RS13000	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DJ476_RS13000	COG0674	pyruvate-flavodoxin oxidoreductase activity
DJ476_RS13005	COG1013	pyruvate-flavodoxin oxidoreductase activity
DJ476_RS13010	COG1733	regulation of RNA biosynthetic process
DJ476_RS13015	COG0702	epimerase
DJ476_RS13055	COG0561	phosphatase activity
DJ476_RS13080	COG1131	(ABC) transporter
DJ476_RS13090	COG0142	geranyltranstransferase activity
DJ476_RS13095	COG3104	oligopeptide transport
DJ476_RS13120	COG0514	ATP-dependent DNA helicase (RecQ)
DJ476_RS13125	COG1007	ATP synthesis coupled electron transport
DJ476_RS13135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DJ476_RS13140	COG0713	ATP synthesis coupled electron transport
DJ476_RS13145	COG0839	Belongs to the complex I subunit 6 family
DJ476_RS13150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DJ476_RS13155	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DJ476_RS13160	COG1034	ATP synthesis coupled electron transport
DJ476_RS13165	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DJ476_RS13175	COG0649	NAD binding
DJ476_RS13180	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DJ476_RS13185	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DJ476_RS13260	COG2226	methyltransferase
DJ476_RS13295	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DJ476_RS13305	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DJ476_RS13310	COG1278	Cold shock
DJ476_RS13345	COG0318	PFAM AMP-dependent synthetase and ligase
DJ476_RS13360	COG1024	Enoyl-CoA hydratase
DJ476_RS13385	COG1309	transcriptional regulator
DJ476_RS13395	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS13415	COG0259	pyridoxamine-phosphate oxidase activity
DJ476_RS13420	COG0501	Belongs to the peptidase M48B family
DJ476_RS13450	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS13455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS13460	COG4592	Periplasmic binding protein
DJ476_RS13480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DJ476_RS13495	COG1024	Enoyl-CoA hydratase
DJ476_RS13525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DJ476_RS13550	COG0583	DNA-binding transcription factor activity
DJ476_RS13620	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS13625	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS13645	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS13650	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS13660	COG0318	PFAM AMP-dependent synthetase and ligase
DJ476_RS13725	COG1595	DNA-templated transcription, initiation
DJ476_RS13740	COG0151	Belongs to the GarS family
DJ476_RS13755	COG2264	protein methyltransferase activity
DJ476_RS13770	COG0477	Major facilitator Superfamily
DJ476_RS13810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DJ476_RS13820	COG4821	SIS domain
DJ476_RS13825	COG2205	protein histidine kinase activity
DJ476_RS13830	COG0745	RESPONSE REGULATOR receiver
DJ476_RS13850	COG1136	(ABC) transporter
DJ476_RS13850	COG0577	efflux transmembrane transporter activity
DJ476_RS13855	COG1136	(ABC) transporter
DJ476_RS13855	COG0577	efflux transmembrane transporter activity
DJ476_RS13865	COG0259	pyridoxamine-phosphate oxidase activity
DJ476_RS13890	COG2124	cytochrome p450
DJ476_RS13900	COG2205	protein histidine kinase activity
DJ476_RS13970	COG1024	Enoyl-CoA hydratase
DJ476_RS13975	COG0318	PFAM AMP-dependent synthetase and ligase
DJ476_RS13990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DJ476_RS14010	COG1051	belongs to the nudix hydrolase family
DJ476_RS14015	COG5006	permease, DMT superfamily
DJ476_RS14025	COG0583	DNA-binding transcription factor activity
DJ476_RS14040	COG3896	Chloramphenicol phosphotransferase-like protein
DJ476_RS14045	COG0277	FAD linked oxidase domain protein
DJ476_RS14045	COG0247	lactate metabolic process
DJ476_RS14050	COG2205	protein histidine kinase activity
DJ476_RS14080	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DJ476_RS14090	COG2318	DinB family
DJ476_RS14100	COG1302	Protein conserved in bacteria
DJ476_RS14125	COG1335	isochorismatase
DJ476_RS14185	COG0697	spore germination
DJ476_RS14195	COG1309	transcriptional regulator
DJ476_RS14215	COG1051	belongs to the nudix hydrolase family
DJ476_RS14285	COG0583	DNA-binding transcription factor activity
DJ476_RS14290	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS14295	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS14300	COG0515	serine threonine protein kinase
DJ476_RS14355	COG2267	carboxylic ester hydrolase activity
DJ476_RS14400	COG2252	PERMEase
DJ476_RS14410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DJ476_RS14430	COG2814	Major facilitator Superfamily
DJ476_RS14440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DJ476_RS14445	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DJ476_RS14450	COG1278	Cold shock
DJ476_RS14470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS14475	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS14480	COG1120	ATPase activity
DJ476_RS14485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DJ476_RS14510	COG1846	Transcriptional regulator
DJ476_RS14515	COG1061	Type III restriction enzyme res subunit
DJ476_RS14530	COG3973	AAA domain
DJ476_RS14535	COG3142	Participates in the control of copper homeostasis
DJ476_RS14545	COG1984	allophanate hydrolase subunit 2
DJ476_RS14550	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DJ476_RS14555	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DJ476_RS14590	COG1737	Transcriptional regulator
DJ476_RS14595	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DJ476_RS14600	COG1263	PTS System
DJ476_RS14600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DJ476_RS14620	COG2197	response regulator
DJ476_RS14625	COG4251	negative regulation of phosphorylation
DJ476_RS14665	COG1175	transmembrane transport
DJ476_RS14670	COG0395	ABC-type sugar transport system, permease component
DJ476_RS14710	COG1595	DNA-templated transcription, initiation
DJ476_RS14735	COG1132	(ABC) transporter
DJ476_RS14780	COG0463	Glycosyl transferase, family 2
DJ476_RS14785	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DJ476_RS14790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DJ476_RS14790	COG1877	trehalose-phosphatase activity
DJ476_RS14810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DJ476_RS14835	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DJ476_RS14860	COG0666	response to abiotic stimulus
DJ476_RS14875	COG2197	response regulator
DJ476_RS14895	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DJ476_RS14915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DJ476_RS14965	COG3842	ATPase activity
DJ476_RS14975	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DJ476_RS14990	COG0215	cysteine-tRNA ligase activity
DJ476_RS15000	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DJ476_RS15005	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DJ476_RS15010	COG1329	Transcriptional regulator
DJ476_RS15030	COG5002	protein histidine kinase activity
DJ476_RS15045	COG0588	phosphoglycerate mutase activity
DJ476_RS15090	COG0438	transferase activity, transferring glycosyl groups
DJ476_RS15140	COG2318	DinB family
DJ476_RS15180	COG4552	Acetyltransferase involved in intracellular survival and related
DJ476_RS15195	COG1490	D-aminoacyl-tRNA deacylase activity
DJ476_RS15210	COG3485	protocatechuate 3,4-dioxygenase
DJ476_RS15250	COG2897	thiosulfate sulfurtransferase activity
DJ476_RS15275	COG0745	RESPONSE REGULATOR receiver
DJ476_RS15280	COG1609	Transcriptional regulator
DJ476_RS15285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DJ476_RS15360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DJ476_RS15365	COG0640	Transcriptional regulator
DJ476_RS15380	COG0154	amidase activity
DJ476_RS15400	COG0737	Belongs to the 5'-nucleotidase family
DJ476_RS15415	COG0456	acetyltransferase
DJ476_RS15425	COG1725	Transcriptional regulator
DJ476_RS15430	COG1116	anion transmembrane transporter activity
DJ476_RS15450	COG0406	alpha-ribazole phosphatase activity
DJ476_RS15450	COG0494	nUDIX hydrolase
DJ476_RS15455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DJ476_RS15475	COG0306	phosphate transporter
DJ476_RS15485	COG1937	Protein conserved in bacteria
DJ476_RS15500	COG0671	phosphoesterase, PA-phosphatase related
DJ476_RS15505	COG1196	nuclear chromosome segregation
DJ476_RS15505	COG0741	lytic transglycosylase activity
DJ476_RS15505	COG0739	heme binding
DJ476_RS15555	COG0456	acetyltransferase
DJ476_RS15580	COG1846	Transcriptional regulator
DJ476_RS15595	COG1252	NADH dehydrogenase
DJ476_RS15620	COG0579	oxidoreductase
DJ476_RS15625	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DJ476_RS15635	COG1196	nuclear chromosome segregation
DJ476_RS15635	COG0741	lytic transglycosylase activity
DJ476_RS15635	COG0739	heme binding
DJ476_RS15645	COG0789	Transcriptional regulator
DJ476_RS15700	COG0513	Belongs to the DEAD box helicase family
DJ476_RS15710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DJ476_RS15715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DJ476_RS15745	COG0785	Cytochrome C biogenesis protein
DJ476_RS15750	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DJ476_RS15750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DJ476_RS15760	COG1643	Atp-dependent helicase
DJ476_RS15795	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DJ476_RS15810	COG2318	DinB family
DJ476_RS15815	COG1196	nuclear chromosome segregation
DJ476_RS15815	COG0739	heme binding
DJ476_RS15815	COG0741	lytic transglycosylase activity
DJ476_RS15825	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DJ476_RS15830	COG0047	phosphoribosylformylglycinamidine synthase activity
DJ476_RS15835	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DJ476_RS15855	COG1131	(ABC) transporter
DJ476_RS15870	COG2197	response regulator
DJ476_RS15880	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DJ476_RS15900	COG0151	Belongs to the GarS family
DJ476_RS15935	COG0492	ferredoxin-NADP+ reductase activity
DJ476_RS15975	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DJ476_RS15995	COG1476	TRANSCRIPTIONal
DJ476_RS16040	COG4941	Belongs to the sigma-70 factor family
DJ476_RS16080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DJ476_RS16140	COG1191	sigma factor activity
DJ476_RS16145	COG1191	sigma factor activity
DJ476_RS16160	COG1846	Transcriptional regulator
DJ476_RS16170	COG2353	YceI-like domain
DJ476_RS16175	COG3467	pyridoxamine 5'-phosphate
DJ476_RS16205	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DJ476_RS16215	COG2205	protein histidine kinase activity
DJ476_RS16220	COG0745	RESPONSE REGULATOR receiver
DJ476_RS16310	COG1396	sequence-specific DNA binding
DJ476_RS16625	COG0318	PFAM AMP-dependent synthetase and ligase
DJ476_RS16630	COG1595	DNA-templated transcription, initiation
DJ476_RS16655	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS16680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DJ476_RS16695	COG0653	protein targeting
DJ476_RS16715	COG0006	proline dipeptidase activity
DJ476_RS16735	COG1999	signal sequence binding
DJ476_RS16745	COG2372	response to copper ion
DJ476_RS16750	COG2837	iron assimilation
DJ476_RS16755	COG0077	Prephenate dehydratase
DJ476_RS16760	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DJ476_RS16765	COG0561	phosphatase activity
DJ476_RS16790	COG1131	(ABC) transporter
DJ476_RS16805	COG0789	Transcriptional regulator
DJ476_RS16810	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DJ476_RS16820	COG0561	phosphatase activity
DJ476_RS16830	COG4988	ABC transporter
DJ476_RS16835	COG1294	oxidase, subunit
DJ476_RS16840	COG1271	oxidase subunit
DJ476_RS16845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DJ476_RS16850	COG1609	Transcriptional regulator
DJ476_RS16855	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DJ476_RS16865	COG3152	Membrane
DJ476_RS16870	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DJ476_RS16895	COG0662	Cupin 2, conserved barrel domain protein
DJ476_RS16900	COG1950	PFAM Membrane protein of
DJ476_RS16905	COG0626	cystathionine gamma-synthase activity
DJ476_RS16925	COG2814	Major facilitator Superfamily
DJ476_RS16955	COG0305	Participates in initiation and elongation during chromosome replication
DJ476_RS16960	COG0534	Mate efflux family protein
DJ476_RS16965	COG0359	binds to the 23S rRNA
DJ476_RS16970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DJ476_RS16975	COG0629	single-stranded DNA binding
DJ476_RS16980	COG0360	Binds together with S18 to 16S ribosomal RNA
DJ476_RS17025	COG0617	tRNA 3'-terminal CCA addition
DJ476_RS17040	COG0515	serine threonine protein kinase
DJ476_RS17040	COG2815	serine threonine protein kinase
DJ476_RS17045	COG1595	DNA-templated transcription, initiation
DJ476_RS17055	COG0492	ferredoxin-NADP+ reductase activity
DJ476_RS17060	COG3118	belongs to the thioredoxin family
DJ476_RS17075	COG1192	Involved in chromosome partitioning
DJ476_RS17080	COG0357	Ribosomal RNA small subunit methyltransferase G
DJ476_RS17090	COG0706	membrane insertase activity
DJ476_RS17095	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DJ476_RS17100	COG0594	ribonuclease P activity
DJ476_RS17120	COG0592	DNA-directed DNA polymerase activity
DJ476_RS17125	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DJ476_RS17130	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DJ476_RS17135	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DJ476_RS17145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DJ476_RS17180	COG0515	serine threonine protein kinase
DJ476_RS17210	COG0705	Rhomboid family
DJ476_RS17225	COG3764	Sortase (surface protein transpeptidase)
DJ476_RS17240	COG3764	Sortase (surface protein transpeptidase)
DJ476_RS17245	COG3764	Sortase (surface protein transpeptidase)
DJ476_RS17250	COG0515	serine threonine protein kinase
DJ476_RS17255	COG0768	penicillin binding
DJ476_RS17270	COG1716	ATPase activity
DJ476_RS17275	COG1716	ATPase activity
DJ476_RS17300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DJ476_RS17305	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS17310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DJ476_RS17315	COG2151	metal-sulfur cluster biosynthetic enzyme
DJ476_RS17320	COG3396	Phenylacetate-CoA oxygenase
DJ476_RS17325	COG3460	Phenylacetate-CoA oxygenase
DJ476_RS17330	COG3396	Phenylacetate-CoA oxygenase
DJ476_RS17355	COG1309	transcriptional regulator
DJ476_RS17360	COG1522	sequence-specific DNA binding
DJ476_RS17380	COG0746	molybdenum cofactor guanylyltransferase activity
DJ476_RS17390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DJ476_RS17395	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS17395	COG3321	synthase
DJ476_RS17395	COG0604	alcohol dehydrogenase
DJ476_RS17410	COG4591	ABC-type transport system involved in lipoprotein release permease component
DJ476_RS17410	COG1136	(ABC) transporter
DJ476_RS17425	COG0515	serine threonine protein kinase
DJ476_RS17430	COG0515	serine threonine protein kinase
DJ476_RS17455	COG0022	dehydrogenase e1 component
DJ476_RS17460	COG0508	dehydrogenase complex catalyzes the overall conversion of
DJ476_RS17515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DJ476_RS17535	COG1362	aminopeptidase activity
DJ476_RS17540	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS17550	COG1741	Belongs to the pirin family
DJ476_RS17565	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DJ476_RS17580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DJ476_RS17585	COG0745	RESPONSE REGULATOR receiver
DJ476_RS17590	COG2205	protein histidine kinase activity
DJ476_RS17620	COG0431	NADPH-dependent FMN reductase
DJ476_RS17635	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DJ476_RS17635	COG1672	PFAM Archaeal ATPase
DJ476_RS17650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DJ476_RS17655	COG2015	COG2015, Alkyl sulfatase and related hydrolases
DJ476_RS17660	COG0180	Tryptophanyl-tRNA synthetase
DJ476_RS17670	COG2255	four-way junction helicase activity
DJ476_RS17695	COG0475	glutathione-regulated potassium exporter activity
DJ476_RS17700	COG0490	domain, Protein
DJ476_RS17735	COG2268	Band 7 protein
DJ476_RS17800	COG1278	Cold shock
DJ476_RS17805	COG0513	Belongs to the DEAD box helicase family
DJ476_RS17810	COG2409	Drug exporters of the RND superfamily
DJ476_RS17820	COG0475	glutathione-regulated potassium exporter activity
DJ476_RS17855	COG3585	molybdate ion transport
DJ476_RS17880	COG2124	cytochrome p450
DJ476_RS17885	COG2124	cytochrome p450
DJ476_RS17920	COG1609	Transcriptional regulator
DJ476_RS17940	COG0745	RESPONSE REGULATOR receiver
DJ476_RS17945	COG2205	protein histidine kinase activity
DJ476_RS17970	COG1902	pentaerythritol trinitrate reductase activity
DJ476_RS17985	COG0367	asparagine synthase
DJ476_RS18000	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS18045	COG2130	NADP-dependent
DJ476_RS18055	COG1533	DNA photolyase activity
DJ476_RS18060	COG3046	protein related to deoxyribodipyrimidine photolyase
DJ476_RS18080	COG0745	RESPONSE REGULATOR receiver
DJ476_RS18085	COG2205	protein histidine kinase activity
DJ476_RS18105	COG2197	response regulator
DJ476_RS18120	COG1131	(ABC) transporter
DJ476_RS18130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DJ476_RS18135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DJ476_RS18140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DJ476_RS18145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DJ476_RS18175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DJ476_RS18180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DJ476_RS18195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DJ476_RS18210	COG0477	Major facilitator Superfamily
DJ476_RS18220	COG3851	Histidine kinase
DJ476_RS18235	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS18240	COG1309	transcriptional regulator
DJ476_RS18245	COG2197	response regulator
DJ476_RS18250	COG1131	(ABC) transporter
DJ476_RS18290	COG1136	(ABC) transporter
DJ476_RS18330	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DJ476_RS18410	COG0717	Belongs to the dCTP deaminase family
DJ476_RS18430	COG0247	lactate metabolic process
DJ476_RS18430	COG2181	nitrate reductase activity
DJ476_RS18445	COG0443	Heat shock 70 kDa protein
DJ476_RS18450	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DJ476_RS18455	COG0484	heat shock protein binding
DJ476_RS18460	COG0789	Transcriptional regulator
DJ476_RS18490	COG0542	response to heat
DJ476_RS18515	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DJ476_RS18530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DJ476_RS18535	COG0191	fructose-bisphosphate aldolase activity
DJ476_RS18540	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DJ476_RS18545	COG0477	Major facilitator Superfamily
DJ476_RS18560	COG3844	kynureninase activity
DJ476_RS18570	COG0702	epimerase
DJ476_RS18580	COG2197	response regulator
DJ476_RS18585	COG2124	cytochrome p450
DJ476_RS18605	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DJ476_RS18610	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DJ476_RS18620	COG0590	tRNA wobble adenosine to inosine editing
DJ476_RS18675	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS18680	COG0662	Cupin 2, conserved barrel domain protein
DJ476_RS18690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DJ476_RS18715	COG0667	Aldo Keto reductase
DJ476_RS18725	COG0592	DNA-directed DNA polymerase activity
DJ476_RS18735	COG3226	Transcriptional regulator
DJ476_RS18745	COG0738	Major facilitator superfamily
DJ476_RS18760	COG0693	protein deglycase activity
DJ476_RS18770	COG1802	Transcriptional regulator
DJ476_RS18785	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DJ476_RS18790	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DJ476_RS18815	COG1595	DNA-templated transcription, initiation
DJ476_RS18835	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DJ476_RS18845	COG2755	lipolytic protein G-D-S-L family
DJ476_RS18865	COG0659	secondary active sulfate transmembrane transporter activity
DJ476_RS18870	COG0789	Transcriptional regulator
DJ476_RS18880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DJ476_RS18880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DJ476_RS18895	COG1937	Protein conserved in bacteria
DJ476_RS18900	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DJ476_RS18915	COG1408	metallophosphoesterase
DJ476_RS18920	COG1610	YqeY-like protein
DJ476_RS18925	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DJ476_RS18940	COG0003	Pfam Anion-transporting ATPase
DJ476_RS18965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DJ476_RS18995	COG2267	carboxylic ester hydrolase activity
DJ476_RS19010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DJ476_RS19015	COG0288	reversible hydration of carbon dioxide
DJ476_RS19075	COG1205	dead DEAH box helicase
DJ476_RS19075	COG1111	helicase
DJ476_RS19080	COG1366	Belongs to the anti-sigma-factor antagonist family
DJ476_RS19085	COG2172	sigma factor antagonist activity
DJ476_RS19090	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DJ476_RS19100	COG2890	protein-(glutamine-N5) methyltransferase activity
DJ476_RS19110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DJ476_RS19110	COG1754	DNA topoisomerase type I activity
DJ476_RS19115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DJ476_RS19120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DJ476_RS19140	COG1401	restriction endodeoxyribonuclease activity
DJ476_RS19155	COG0326	Molecular chaperone. Has ATPase activity
DJ476_RS19180	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DJ476_RS19210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DJ476_RS19210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DJ476_RS19245	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS19265	COG0076	glutamate decarboxylase activity
DJ476_RS19270	COG0655	NAD(P)H dehydrogenase (quinone) activity
DJ476_RS19280	COG0393	Putative heavy-metal-binding
DJ476_RS19285	COG0586	Pfam SNARE associated Golgi protein
DJ476_RS19300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DJ476_RS19305	COG2027	D-alanyl-D-alanine carboxypeptidase
DJ476_RS19330	COG0302	gtp cyclohydrolase
DJ476_RS19345	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DJ476_RS19365	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DJ476_RS19365	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DJ476_RS19375	COG0517	IMP dehydrogenase activity
DJ476_RS19375	COG1125	glycine betaine transport
DJ476_RS19380	COG1174	glycine betaine transport
DJ476_RS19385	COG1174	glycine betaine transport
DJ476_RS19400	COG0649	NAD binding
DJ476_RS19415	COG2197	response regulator
DJ476_RS19440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DJ476_RS19445	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DJ476_RS19455	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DJ476_RS19475	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DJ476_RS19510	COG0739	heme binding
DJ476_RS19515	COG2205	protein histidine kinase activity
DJ476_RS19520	COG0745	RESPONSE REGULATOR receiver
DJ476_RS19530	COG1595	DNA-templated transcription, initiation
DJ476_RS19535	COG1194	a g-specific adenine glycosylase
DJ476_RS19550	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DJ476_RS19570	COG0248	Ppx GppA phosphatase
DJ476_RS19575	COG1082	Xylose isomerase domain protein TIM barrel
DJ476_RS19585	COG0129	dihydroxy-acid dehydratase activity
DJ476_RS19595	COG4991	sh3 domain protein
DJ476_RS19605	COG1129	ABC transporter
DJ476_RS19605	COG0842	Transport permease protein
DJ476_RS19615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DJ476_RS19640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DJ476_RS19645	COG2223	nitrite transmembrane transporter activity
DJ476_RS19675	COG0204	Acyl-transferase
DJ476_RS19700	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DJ476_RS19705	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DJ476_RS19710	COG0181	hydroxymethylbilane synthase activity
DJ476_RS19715	COG1648	precorrin-2 dehydrogenase activity
DJ476_RS19715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DJ476_RS19720	COG0113	porphobilinogen synthase activity
DJ476_RS19750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DJ476_RS19790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DJ476_RS19800	COG0018	arginyl-trna synthetase
DJ476_RS19805	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DJ476_RS19810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DJ476_RS19830	COG1690	Belongs to the RtcB family
DJ476_RS19870	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DJ476_RS19875	COG0406	alpha-ribazole phosphatase activity
DJ476_RS19880	COG2382	esterase
DJ476_RS19895	COG0785	Cytochrome C biogenesis protein
DJ476_RS19900	COG1333	cytochrome c biogenesis protein
DJ476_RS19905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DJ476_RS19915	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DJ476_RS19920	COG1612	heme a metabolic process
DJ476_RS19920	COG0109	protoheme IX farnesyltransferase activity
DJ476_RS19930	COG0163	prenyltransferase activity
DJ476_RS19940	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DJ476_RS19955	COG1301	dicarboxylic acid transport
DJ476_RS19975	COG0318	PFAM AMP-dependent synthetase and ligase
DJ476_RS20005	COG1309	transcriptional regulator
DJ476_RS20020	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS20025	COG0183	Belongs to the thiolase family
DJ476_RS20035	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
DJ476_RS20095	COG1309	transcriptional regulator
DJ476_RS20100	COG0667	Aldo Keto reductase
DJ476_RS20160	COG0768	penicillin binding
DJ476_RS20170	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DJ476_RS20200	COG3655	Transcriptional regulator
DJ476_RS20265	COG1686	Belongs to the peptidase S11 family
DJ476_RS20315	COG3903	Transcriptional regulator
DJ476_RS20315	COG3629	intracellular signal transduction
DJ476_RS20345	COG0463	Glycosyl transferase, family 2
DJ476_RS20370	COG0475	glutathione-regulated potassium exporter activity
DJ476_RS20375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DJ476_RS20405	COG2197	response regulator
DJ476_RS20415	COG1021	2,3-dihydroxybenzoate-AMP ligase
DJ476_RS20435	COG1846	Transcriptional regulator
DJ476_RS20440	COG3384	dioxygenase
DJ476_RS20465	COG0477	Major facilitator Superfamily
DJ476_RS20485	COG0243	molybdopterin cofactor binding
DJ476_RS20490	COG0437	4 iron, 4 sulfur cluster binding
DJ476_RS20510	COG1970	mechanosensitive ion channel activity
DJ476_RS20520	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DJ476_RS20535	COG3263	regulation of cellular component size
DJ476_RS20545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DJ476_RS20550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DJ476_RS20560	COG0315	cyclic pyranopterin monophosphate synthase activity
DJ476_RS20565	COG0521	Mo-molybdopterin cofactor biosynthetic process
DJ476_RS20595	COG2340	Cysteine-rich secretory protein family
DJ476_RS20605	COG0708	Exodeoxyribonuclease III
DJ476_RS20615	COG2072	flavoprotein involved in K transport
DJ476_RS20625	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS20640	COG0793	Belongs to the peptidase S41A family
DJ476_RS20640	COG4946	Tricorn protease homolog
DJ476_RS20650	COG2409	Drug exporters of the RND superfamily
DJ476_RS20660	COG0310	cobalt ion transport
DJ476_RS20665	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DJ476_RS20670	COG1122	ATPase activity
DJ476_RS20675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DJ476_RS20720	COG1115	amino acid carrier protein
DJ476_RS20770	COG0442	prolyl-tRNA aminoacylation
DJ476_RS20840	COG0084	hydrolase, TatD family'
DJ476_RS20850	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DJ476_RS20855	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DJ476_RS20860	COG2318	DinB family
DJ476_RS20865	COG2813	Specifically methylates the guanine in position
DJ476_RS20885	COG0488	(ABC) transporter
DJ476_RS20910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DJ476_RS20925	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DJ476_RS20935	COG2197	response regulator
DJ476_RS20945	COG4106	trans-aconitate 2-methyltransferase activity
DJ476_RS20965	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DJ476_RS20975	COG0193	aminoacyl-tRNA hydrolase activity
DJ476_RS20980	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DJ476_RS20985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DJ476_RS20990	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DJ476_RS21000	COG4585	Histidine kinase
DJ476_RS21040	COG1607	acyl-coa hydrolase
DJ476_RS21055	COG1917	Cupin 2, conserved barrel domain protein
DJ476_RS21075	COG2124	cytochrome p450
DJ476_RS21105	COG2814	Major facilitator Superfamily
DJ476_RS21115	COG1136	(ABC) transporter
DJ476_RS21120	COG0577	efflux transmembrane transporter activity
DJ476_RS21130	COG3903	Transcriptional regulator
DJ476_RS21130	COG3629	intracellular signal transduction
DJ476_RS21160	COG1994	Peptidase M50
DJ476_RS21280	COG2124	cytochrome p450
DJ476_RS21300	COG0148	phosphopyruvate hydratase activity
DJ476_RS21335	COG1252	NADH dehydrogenase
DJ476_RS21340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DJ476_RS21345	COG0577	efflux transmembrane transporter activity
DJ476_RS21345	COG1136	(ABC) transporter
DJ476_RS21350	COG0577	efflux transmembrane transporter activity
DJ476_RS21350	COG1136	(ABC) transporter
DJ476_RS21375	COG0183	Belongs to the thiolase family
DJ476_RS21380	COG2755	lipolytic protein G-D-S-L family
DJ476_RS21425	COG0531	amino acid
DJ476_RS21430	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DJ476_RS21435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DJ476_RS21445	COG1228	amidohydrolase
DJ476_RS21450	COG1191	sigma factor activity
DJ476_RS21455	COG1366	Belongs to the anti-sigma-factor antagonist family
DJ476_RS21485	COG3104	oligopeptide transport
DJ476_RS21490	COG0745	RESPONSE REGULATOR receiver
DJ476_RS21495	COG2205	protein histidine kinase activity
DJ476_RS21535	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DJ476_RS21565	COG1316	TRANSCRIPTIONal
DJ476_RS21575	COG1316	TRANSCRIPTIONal
DJ476_RS21585	COG1316	TRANSCRIPTIONal
DJ476_RS21590	COG1316	TRANSCRIPTIONal
DJ476_RS21605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DJ476_RS21615	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DJ476_RS21615	COG0778	Nitroreductase
DJ476_RS21620	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DJ476_RS21665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DJ476_RS21670	COG2835	tetraacyldisaccharide 4'-kinase activity
DJ476_RS21680	COG1482	cell wall glycoprotein biosynthetic process
DJ476_RS21690	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DJ476_RS21745	COG0714	Associated with various cellular activities
DJ476_RS21765	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DJ476_RS21770	COG0745	RESPONSE REGULATOR receiver
DJ476_RS21775	COG5002	protein histidine kinase activity
DJ476_RS21775	COG5000	phosphorelay sensor kinase activity
DJ476_RS21780	COG0823	Involved in the tonB-independent uptake of proteins
DJ476_RS21790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DJ476_RS21795	COG2197	response regulator
DJ476_RS21810	COG0653	protein targeting
DJ476_RS21835	COG2902	Dehydrogenase
DJ476_RS21840	COG1134	teichoic acid transport
DJ476_RS21850	COG1309	transcriptional regulator
DJ476_RS21860	COG0395	ABC-type sugar transport system, permease component
DJ476_RS21865	COG1175	transmembrane transport
DJ476_RS21870	COG1653	transport
DJ476_RS21880	COG0515	serine threonine protein kinase
DJ476_RS21885	COG0515	serine threonine protein kinase
DJ476_RS21890	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DJ476_RS21905	COG2884	Cell division ATP-binding protein ftsE
DJ476_RS21910	COG2177	Part of the ABC transporter FtsEX involved in
DJ476_RS21915	COG0793	Belongs to the peptidase S41A family
DJ476_RS21920	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DJ476_RS21970	COG2223	nitrite transmembrane transporter activity
DJ476_RS22000	COG3973	AAA domain
DJ476_RS22000	COG3973	AAA domain
DJ476_RS22010	COG0776	regulation of translation
DJ476_RS22015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DJ476_RS22020	COG1678	Uncharacterized ACR, COG1678
DJ476_RS22040	COG0395	ABC-type sugar transport system, permease component
DJ476_RS22045	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DJ476_RS22085	COG3654	unkown
DJ476_RS22090	COG1061	Type III restriction enzyme res subunit
DJ476_RS22100	COG3480	Lon protease (S16) C-terminal proteolytic domain
DJ476_RS22105	COG1732	Glycine betaine
DJ476_RS22110	COG1174	glycine betaine transport
DJ476_RS22120	COG1174	glycine betaine transport
DJ476_RS22130	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DJ476_RS22140	COG0277	FAD linked oxidase domain protein
DJ476_RS22175	COG1335	isochorismatase
DJ476_RS22185	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DJ476_RS22195	COG1113	amino acid transport
DJ476_RS22210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS22240	COG1234	tRNA 3'-trailer cleavage
DJ476_RS22245	COG1263	PTS System
DJ476_RS22250	COG1263	PTS System
DJ476_RS22255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DJ476_RS22260	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DJ476_RS22270	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DJ476_RS22285	COG0477	Major facilitator Superfamily
DJ476_RS22325	COG4555	ABC transporter
DJ476_RS22350	COG2313	pseudouridylate synthase activity
DJ476_RS22360	COG0546	phosphoglycolate phosphatase activity
DJ476_RS22380	COG0596	Alpha beta hydrolase
DJ476_RS22405	COG0789	Transcriptional regulator
DJ476_RS22440	COG0745	RESPONSE REGULATOR receiver
DJ476_RS22450	COG1215	transferase activity, transferring glycosyl groups
DJ476_RS22505	COG3764	Sortase (surface protein transpeptidase)
DJ476_RS22515	COG0706	membrane insertase activity
DJ476_RS22525	COG4702	Belongs to the UPF0303 family
DJ476_RS22530	COG0673	inositol 2-dehydrogenase activity
DJ476_RS22570	COG2188	Transcriptional regulator
DJ476_RS22575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DJ476_RS22645	COG3397	chitin binding
DJ476_RS22660	COG1126	abc transporter atp-binding protein
DJ476_RS22665	COG0765	amino acid transport
DJ476_RS22670	COG0765	amino acid transport
DJ476_RS22675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DJ476_RS22690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DJ476_RS22745	COG0588	phosphoglycerate mutase activity
DJ476_RS22770	COG0745	RESPONSE REGULATOR receiver
DJ476_RS22785	COG2985	domain, Protein
DJ476_RS22800	COG0395	ABC-type sugar transport system, permease component
DJ476_RS22835	COG4977	sequence-specific DNA binding
DJ476_RS22840	COG0589	response to stress
DJ476_RS22845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DJ476_RS22870	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DJ476_RS22875	COG0076	glutamate decarboxylase activity
DJ476_RS22900	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DJ476_RS22905	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DJ476_RS22915	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS22930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DJ476_RS22935	COG1309	transcriptional regulator
DJ476_RS22955	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DJ476_RS22955	COG2755	lipolytic protein G-D-S-L family
DJ476_RS22975	COG1946	Acyl-CoA thioesterase
DJ476_RS23045	COG0028	Belongs to the TPP enzyme family
DJ476_RS23075	COG1472	Belongs to the glycosyl hydrolase 3 family
DJ476_RS23080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DJ476_RS23085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DJ476_RS23090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DJ476_RS23095	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS23145	COG4974	Belongs to the 'phage' integrase family
DJ476_RS23175	COG1404	Belongs to the peptidase S8 family
DJ476_RS23235	COG1609	Transcriptional regulator
DJ476_RS23240	COG0673	inositol 2-dehydrogenase activity
DJ476_RS23260	COG2409	Drug exporters of the RND superfamily
DJ476_RS23320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DJ476_RS23345	COG2409	Drug exporters of the RND superfamily
DJ476_RS23350	COG0500	methyltransferase
DJ476_RS23350	COG3615	Tellurite resistance protein tehB
DJ476_RS23360	COG2318	DinB family
DJ476_RS23380	COG3718	enzyme involved in inositol metabolism
DJ476_RS23385	COG3962	Belongs to the TPP enzyme family
DJ476_RS23405	COG1131	(ABC) transporter
DJ476_RS23430	COG4585	Histidine kinase
DJ476_RS23435	COG2197	response regulator
DJ476_RS23450	COG3903	Transcriptional regulator
DJ476_RS23450	COG3629	intracellular signal transduction
DJ476_RS23470	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DJ476_RS23475	COG0629	single-stranded DNA binding
DJ476_RS23500	COG2346	COG2346, Truncated hemoglobins
DJ476_RS23505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DJ476_RS23535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DJ476_RS23550	COG1486	melibiose metabolic process
DJ476_RS23555	COG0395	ABC-type sugar transport system, permease component
DJ476_RS23560	COG1175	transmembrane transport
DJ476_RS23570	COG1940	carbohydrate kinase activity
DJ476_RS23575	COG0668	transmembrane transport
DJ476_RS23585	COG3291	Pkd domain containing protein
DJ476_RS23585	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DJ476_RS23605	COG4266	Belongs to the allantoicase family
DJ476_RS23625	COG2337	Toxic component of a toxin-antitoxin (TA) module
DJ476_RS23655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DJ476_RS23670	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS23695	COG3655	Transcriptional regulator
DJ476_RS23705	COG0110	maltose O-acetyltransferase activity
DJ476_RS23720	COG0640	Transcriptional regulator
DJ476_RS23725	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DJ476_RS23730	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DJ476_RS23735	COG0783	Belongs to the Dps family
DJ476_RS23745	COG1113	amino acid transport
DJ476_RS23750	COG1113	amino acid transport
DJ476_RS23755	COG1268	BioY protein
DJ476_RS23760	COG1113	amino acid transport
DJ476_RS23775	COG4552	Acetyltransferase involved in intracellular survival and related
DJ476_RS23785	COG0475	glutathione-regulated potassium exporter activity
DJ476_RS23790	COG3594	Acyltransferase
DJ476_RS23810	COG0544	peptidyl-prolyl cis-trans isomerase activity
DJ476_RS23815	COG0740	serine-type endopeptidase activity
DJ476_RS23820	COG0740	serine-type endopeptidase activity
DJ476_RS23825	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DJ476_RS23835	COG0525	valine-tRNA ligase activity
DJ476_RS23840	COG0285	dihydrofolate synthase activity
DJ476_RS23850	COG0105	UTP biosynthetic process
DJ476_RS23855	COG1077	Cell shape determining protein MreB Mrl
DJ476_RS23870	COG0768	penicillin binding
DJ476_RS23875	COG0772	Belongs to the SEDS family
DJ476_RS23900	COG1530	ribonuclease E activity
DJ476_RS23945	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DJ476_RS23950	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DJ476_RS23955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DJ476_RS23980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DJ476_RS23990	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DJ476_RS24005	COG0501	Belongs to the peptidase M48B family
DJ476_RS24010	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DJ476_RS24020	COG0799	negative regulation of ribosome biogenesis
DJ476_RS24025	COG0588	phosphoglycerate mutase activity
DJ476_RS24060	COG0495	leucyl-tRNA aminoacylation
DJ476_RS24070	COG1307	EDD domain protein, DegV family
DJ476_RS24075	COG1555	photosystem II stabilization
DJ476_RS24085	COG2353	YceI-like domain
DJ476_RS24100	COG0268	Binds directly to 16S ribosomal RNA
DJ476_RS24105	COG0481	GTPase activity
DJ476_RS24110	COG1022	Amp-dependent synthetase and ligase
DJ476_RS24135	COG1420	regulation of RNA biosynthetic process
DJ476_RS24140	COG0484	heat shock protein binding
DJ476_RS24155	COG0537	adenosine 5'-monophosphoramidase activity
DJ476_RS24160	COG1234	tRNA 3'-trailer cleavage
DJ476_RS24165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DJ476_RS24185	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DJ476_RS24195	COG2315	Protein conserved in bacteria
DJ476_RS24205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DJ476_RS24220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DJ476_RS24230	COG1381	Involved in DNA repair and RecF pathway recombination
DJ476_RS24235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DJ476_RS24245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DJ476_RS24250	COG1121	(ABC) transporter
DJ476_RS24255	COG0803	Belongs to the bacterial solute-binding protein 9 family
DJ476_RS24255	COG3443	Belongs to the bacterial solute-binding protein 9 family
DJ476_RS24260	COG0423	glycine-tRNA ligase activity
DJ476_RS24290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DJ476_RS24320	COG2197	response regulator
DJ476_RS24335	COG0702	epimerase
DJ476_RS24340	COG1733	regulation of RNA biosynthetic process
DJ476_RS24385	COG2066	Belongs to the glutaminase family
DJ476_RS24410	COG0596	Alpha beta hydrolase
DJ476_RS24415	COG1231	oxidoreductase activity
DJ476_RS24425	COG4942	peptidase
DJ476_RS24475	COG2188	Transcriptional regulator
DJ476_RS24490	COG2011	ABC-type metal ion transport system permease component
DJ476_RS24495	COG3842	ATPase activity
DJ476_RS24505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DJ476_RS24505	COG0574	Belongs to the PEP-utilizing enzyme family
DJ476_RS24530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DJ476_RS24530	COG2146	nitrite reductase [NAD(P)H] activity
DJ476_RS24585	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DJ476_RS24595	COG0477	Major facilitator Superfamily
DJ476_RS24605	COG2226	methyltransferase
DJ476_RS24610	COG0358	DNA primase activity
DJ476_RS24615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DJ476_RS24630	COG1070	Carbohydrate kinase
DJ476_RS24660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DJ476_RS24670	COG0733	neurotransmitter:sodium symporter activity
DJ476_RS24680	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DJ476_RS24690	COG0438	transferase activity, transferring glycosyl groups
DJ476_RS24695	COG1914	H( )-stimulated, divalent metal cation uptake system
DJ476_RS24705	COG1942	4-Oxalocrotonate Tautomerase
DJ476_RS24740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DJ476_RS24745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DJ476_RS24755	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DJ476_RS24795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DJ476_RS24795	COG0825	malonyl-CoA metabolic process
DJ476_RS24800	COG0318	PFAM AMP-dependent synthetase and ligase
DJ476_RS24810	COG1522	sequence-specific DNA binding
DJ476_RS24840	COG2130	NADP-dependent
DJ476_RS24845	COG1764	response to oxidative stress
DJ476_RS24855	COG1309	transcriptional regulator
DJ476_RS24880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DJ476_RS24885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DJ476_RS24890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DJ476_RS24905	COG1741	Belongs to the pirin family
DJ476_RS24950	COG0789	Transcriptional regulator
DJ476_RS24955	COG0667	Aldo Keto reductase
DJ476_RS24970	COG2197	response regulator
DJ476_RS24975	COG4585	Histidine kinase
DJ476_RS24990	COG1309	transcriptional regulator
DJ476_RS24995	COG0477	Major facilitator Superfamily
DJ476_RS25005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DJ476_RS25090	COG0582	viral genome integration into host DNA
DJ476_RS25160	COG0546	phosphoglycolate phosphatase activity
DJ476_RS25180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DJ476_RS25215	COG2259	Doxx family
DJ476_RS25265	COG2124	cytochrome p450
DJ476_RS25270	COG0183	Belongs to the thiolase family
DJ476_RS25280	COG3845	ABC transporter
DJ476_RS25350	COG1309	transcriptional regulator
DJ476_RS25355	COG0438	transferase activity, transferring glycosyl groups
DJ476_RS25385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DJ476_RS25425	COG0655	NAD(P)H dehydrogenase (quinone) activity
DJ476_RS25435	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS25450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DJ476_RS25465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DJ476_RS25480	COG3903	Transcriptional regulator
DJ476_RS25480	COG3629	intracellular signal transduction
DJ476_RS25485	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS25490	COG0183	Belongs to the thiolase family
DJ476_RS25500	COG2030	dehydratase
DJ476_RS25520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DJ476_RS25525	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DJ476_RS25545	COG0800	Aldolase
DJ476_RS25550	COG3022	response to hydroperoxide
DJ476_RS25600	COG0384	phenazine biosynthesis protein PhzF
DJ476_RS25610	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS25615	COG3540	Alkaline phosphatase
DJ476_RS25625	COG2814	Major facilitator Superfamily
DJ476_RS25645	COG1834	amidinotransferase
DJ476_RS25665	COG1120	ATPase activity
DJ476_RS25670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS25675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DJ476_RS25695	COG5398	heme oxygenase
DJ476_RS25730	COG1994	Peptidase M50
DJ476_RS25750	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DJ476_RS25755	COG0477	Major facilitator Superfamily
DJ476_RS25770	COG2814	Major facilitator Superfamily
DJ476_RS25775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DJ476_RS25775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DJ476_RS25780	COG2132	Multicopper oxidase
DJ476_RS25795	COG0174	glutamine synthetase
DJ476_RS25875	COG2890	protein-(glutamine-N5) methyltransferase activity
DJ476_RS25880	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DJ476_RS25905	COG3209	COG3209 Rhs family protein
DJ476_RS25905	COG4104	PAAR repeat-containing protein
DJ476_RS25940	COG1609	Transcriptional regulator
DJ476_RS25950	COG1175	transmembrane transport
DJ476_RS25955	COG3833	ABC-type maltose transport systems, permease component
DJ476_RS25960	COG0366	Alpha amylase catalytic
DJ476_RS26020	COG0745	RESPONSE REGULATOR receiver
DJ476_RS26040	COG0673	inositol 2-dehydrogenase activity
DJ476_RS26110	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DJ476_RS26115	COG0321	lipoyl(octanoyl) transferase activity
DJ476_RS26130	COG1090	epimerase
DJ476_RS26150	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DJ476_RS26160	COG0508	dehydrogenase complex catalyzes the overall conversion of
DJ476_RS26165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DJ476_RS26170	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DJ476_RS26175	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DJ476_RS26190	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DJ476_RS26190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DJ476_RS26195	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DJ476_RS26210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DJ476_RS26235	COG4585	Histidine kinase
DJ476_RS26240	COG2197	response regulator
DJ476_RS26245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DJ476_RS26255	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DJ476_RS26275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DJ476_RS26285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DJ476_RS26290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DJ476_RS26300	COG1376	ErfK ybiS ycfS ynhG family protein
DJ476_RS26310	COG1845	cytochrome c oxidase, subunit III
DJ476_RS26315	COG2010	Cytochrome c
DJ476_RS26320	COG0723	plastoquinol--plastocyanin reductase activity
DJ476_RS26325	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DJ476_RS26330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DJ476_RS26335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DJ476_RS26400	COG0003	Pfam Anion-transporting ATPase
DJ476_RS26410	COG1940	carbohydrate kinase activity
DJ476_RS26435	COG4585	Histidine kinase
DJ476_RS26440	COG2197	response regulator
DJ476_RS26445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DJ476_RS26460	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DJ476_RS26470	COG2193	ferroxidase activity
DJ476_RS26475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DJ476_RS26480	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DJ476_RS26485	COG0515	serine threonine protein kinase
DJ476_RS26485	COG2815	serine threonine protein kinase
DJ476_RS26490	COG2022	thiamine diphosphate biosynthetic process
DJ476_RS26500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DJ476_RS26500	COG2022	thiamine diphosphate biosynthetic process
DJ476_RS26520	COG0352	thiamine-phosphate diphosphorylase activity
DJ476_RS26550	COG1511	domain protein
DJ476_RS26555	COG1131	(ABC) transporter
DJ476_RS26565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DJ476_RS26585	COG0714	Associated with various cellular activities
DJ476_RS26595	COG0275	rRNA processing
DJ476_RS26605	COG0768	penicillin binding
DJ476_RS26610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DJ476_RS26620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DJ476_RS26625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DJ476_RS26635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DJ476_RS26660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DJ476_RS26665	COG1799	cell septum assembly
DJ476_RS26675	COG3599	regulation of cell shape
DJ476_RS26685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DJ476_RS26695	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DJ476_RS26745	COG0587	DNA-directed DNA polymerase activity
DJ476_RS26755	COG1432	Conserved Protein
DJ476_RS26780	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DJ476_RS26795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DJ476_RS26800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DJ476_RS26805	COG0131	Imidazoleglycerol-phosphate dehydratase
DJ476_RS26810	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DJ476_RS26815	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DJ476_RS26820	COG0251	oxidation-reduction process
DJ476_RS26825	COG0107	imidazoleglycerol-phosphate synthase activity
DJ476_RS26840	COG2508	Transcriptional regulator
DJ476_RS26850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DJ476_RS26855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DJ476_RS26875	COG0134	indole-3-glycerol-phosphate synthase activity
DJ476_RS26885	COG0133	tryptophan synthase activity
DJ476_RS26890	COG0159	tryptophan synthase activity
DJ476_RS26900	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DJ476_RS26910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DJ476_RS26915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DJ476_RS26945	COG0070	glutamate synthase
DJ476_RS26945	COG0067	glutamate synthase
DJ476_RS26945	COG0069	glutamate synthase activity
DJ476_RS26955	COG0705	Rhomboid family
DJ476_RS26975	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS26980	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS26985	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS26990	COG1309	transcriptional regulator
DJ476_RS26995	COG0183	Belongs to the thiolase family
DJ476_RS27000	COG1278	Cold shock
DJ476_RS27025	COG1024	Enoyl-CoA hydratase
DJ476_RS27030	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS27070	COG0287	Prephenate dehydrogenase
DJ476_RS27070	COG1605	Chorismate mutase
DJ476_RS27090	COG2824	Alkylphosphonate utilization operon protein PhnA
DJ476_RS27100	COG0659	secondary active sulfate transmembrane transporter activity
DJ476_RS27120	COG0737	Belongs to the 5'-nucleotidase family
DJ476_RS27175	COG2050	protein possibly involved in aromatic compounds catabolism
DJ476_RS27210	COG1643	Atp-dependent helicase
DJ476_RS27215	COG2226	methyltransferase
DJ476_RS27235	COG0237	dephospho-CoA kinase activity
DJ476_RS27260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DJ476_RS27280	COG0436	Aminotransferase
DJ476_RS27300	COG2313	pseudouridylate synthase activity
DJ476_RS27310	COG2814	Major facilitator Superfamily
DJ476_RS27315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DJ476_RS27320	COG0584	glycerophosphoryl diester phosphodiesterase
DJ476_RS27330	COG0556	nucleotide-excision repair
DJ476_RS27360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DJ476_RS27385	COG0322	excinuclease ABC activity
DJ476_RS27390	COG1660	Displays ATPase and GTPase activities
DJ476_RS27395	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DJ476_RS27400	COG1481	regulation of sporulation
DJ476_RS27405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DJ476_RS27410	COG0126	phosphoglycerate kinase activity
DJ476_RS27415	COG0149	triose-phosphate isomerase activity
DJ476_RS27420	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DJ476_RS27430	COG0166	Belongs to the GPI family
DJ476_RS27445	COG4195	phage-related replication protein
DJ476_RS27455	COG0363	glucosamine-6-phosphate deaminase activity
DJ476_RS27470	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DJ476_RS27480	COG0109	protoheme IX farnesyltransferase activity
DJ476_RS27490	COG1612	heme a metabolic process
DJ476_RS27500	COG1131	(ABC) transporter
DJ476_RS27515	COG0719	Fe-S assembly protein
DJ476_RS27525	COG0396	ATPase activity
DJ476_RS27530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DJ476_RS27535	COG0822	iron-sulfur transferase activity
DJ476_RS27540	COG2151	metal-sulfur cluster biosynthetic enzyme
DJ476_RS27565	COG3226	Transcriptional regulator
DJ476_RS27585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DJ476_RS27620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DJ476_RS27630	COG0768	penicillin binding
DJ476_RS27660	COG1846	Transcriptional regulator
DJ476_RS27665	COG1902	pentaerythritol trinitrate reductase activity
DJ476_RS27695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DJ476_RS27720	COG1797	cobyrinic acid a,c-diamide synthase activity
DJ476_RS27735	COG1492	cobalamin metabolic process
DJ476_RS27740	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DJ476_RS27755	COG0235	Class ii aldolase
DJ476_RS27780	COG0488	(ABC) transporter
DJ476_RS27830	COG3387	PFAM Glycoside hydrolase 15-related
DJ476_RS27845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DJ476_RS27880	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DJ476_RS27885	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DJ476_RS27905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DJ476_RS27920	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS27925	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DJ476_RS27935	COG2186	Transcriptional regulator
DJ476_RS27955	COG0560	Phosphoserine phosphatase
DJ476_RS27955	COG3830	Belongs to the UPF0237 family
DJ476_RS27960	COG1131	(ABC) transporter
DJ476_RS27960	COG1716	ATPase activity
DJ476_RS27960	COG0842	Transport permease protein
DJ476_RS27970	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DJ476_RS27985	COG2197	response regulator
DJ476_RS28000	COG1119	ATPase activity
DJ476_RS28025	COG1881	PFAM PEBP family protein
DJ476_RS28035	COG2094	Belongs to the DNA glycosylase MPG family
DJ476_RS28065	COG0647	UMP catabolic process
DJ476_RS28070	COG1120	ATPase activity
DJ476_RS28090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DJ476_RS28095	COG0497	DNA recombination
DJ476_RS28100	COG0297	glycogen (starch) synthase activity
DJ476_RS28115	COG0789	Transcriptional regulator
DJ476_RS28125	COG3387	PFAM Glycoside hydrolase 15-related
DJ476_RS28130	COG0504	CTP synthase activity
DJ476_RS28135	COG0494	nUDIX hydrolase
DJ476_RS28145	COG0686	Belongs to the AlaDH PNT family
DJ476_RS28160	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DJ476_RS28165	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DJ476_RS28170	COG1187	pseudouridine synthase activity
DJ476_RS28185	COG0494	nUDIX hydrolase
DJ476_RS28195	COG3541	Predicted nucleotidyltransferase
DJ476_RS28230	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DJ476_RS28240	COG1160	GTP binding
DJ476_RS28255	COG0438	transferase activity, transferring glycosyl groups
DJ476_RS28285	COG0671	phosphoesterase, PA-phosphatase related
DJ476_RS28290	COG0477	Major facilitator Superfamily
DJ476_RS28295	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS28300	COG1799	cell septum assembly
DJ476_RS28310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DJ476_RS28315	COG0765	amino acid transport
DJ476_RS28330	COG1126	abc transporter atp-binding protein
DJ476_RS28335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DJ476_RS28345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DJ476_RS28375	COG0641	radical SAM
DJ476_RS28410	COG0587	DNA-directed DNA polymerase activity
DJ476_RS28415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DJ476_RS28435	COG4565	transcriptional regulatory protein
DJ476_RS28455	COG0346	lactoylglutathione lyase activity
DJ476_RS28470	COG1725	Transcriptional regulator
DJ476_RS28480	COG2755	lipolytic protein G-D-S-L family
DJ476_RS28490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DJ476_RS28500	COG2188	Transcriptional regulator
DJ476_RS28505	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DJ476_RS28510	COG1309	transcriptional regulator
DJ476_RS28515	COG0243	molybdopterin cofactor binding
DJ476_RS28520	COG2851	Citrate transporter
DJ476_RS28540	COG2326	polyphosphate kinase activity
DJ476_RS28555	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS28575	COG0789	Transcriptional regulator
DJ476_RS28595	COG3876	Protein conserved in bacteria
DJ476_RS28605	COG0318	PFAM AMP-dependent synthetase and ligase
DJ476_RS28615	COG2234	aminopeptidase activity
DJ476_RS28615	COG4935	Belongs to the peptidase S8 family
DJ476_RS28620	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS28640	COG2149	membrane
DJ476_RS28645	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DJ476_RS28650	COG3573	Dehydrogenase
DJ476_RS28680	COG3265	gluconokinase activity
DJ476_RS28685	COG2186	Transcriptional regulator
DJ476_RS28695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DJ476_RS28700	COG0564	pseudouridine synthase activity
DJ476_RS28710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DJ476_RS28740	COG0667	Aldo Keto reductase
DJ476_RS28745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DJ476_RS28755	COG0598	Magnesium transport protein CorA
DJ476_RS28775	COG0215	cysteine-tRNA ligase activity
DJ476_RS28785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DJ476_RS28790	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DJ476_RS28795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DJ476_RS28800	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DJ476_RS28805	COG1414	Transcriptional regulator
DJ476_RS28810	COG1410	methionine synthase
DJ476_RS28810	COG0646	methionine synthase
DJ476_RS28820	COG4166	transmembrane transport
DJ476_RS28825	COG2197	response regulator
DJ476_RS28835	COG1994	Peptidase M50
DJ476_RS28835	COG0517	IMP dehydrogenase activity
DJ476_RS28860	COG1222	aaa ATPase
DJ476_RS28865	COG4122	O-methyltransferase activity
DJ476_RS28880	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DJ476_RS28885	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DJ476_RS28890	COG1609	Transcriptional regulator
DJ476_RS28900	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DJ476_RS28905	COG0545	Peptidyl-prolyl cis-trans isomerase
DJ476_RS28915	COG2378	regulation of single-species biofilm formation
DJ476_RS28935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DJ476_RS28940	COG0805	protein transport
DJ476_RS28985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DJ476_RS28990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DJ476_RS29010	COG1595	DNA-templated transcription, initiation
DJ476_RS29035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DJ476_RS29040	COG0517	IMP dehydrogenase activity
DJ476_RS29040	COG4175	Glycine betaine
DJ476_RS29110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DJ476_RS29115	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DJ476_RS29120	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DJ476_RS29125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DJ476_RS29130	COG5002	protein histidine kinase activity
DJ476_RS29135	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DJ476_RS29140	COG0072	phenylalanine-tRNA ligase activity
DJ476_RS29140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DJ476_RS29175	COG1649	PFAM Uncharacterised BCR, COG1649
DJ476_RS29185	COG0697	spore germination
DJ476_RS29200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DJ476_RS29245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DJ476_RS29250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DJ476_RS29255	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DJ476_RS29260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DJ476_RS29265	COG1438	arginine binding
DJ476_RS29275	COG0137	argininosuccinate synthase activity
DJ476_RS29280	COG0165	Argininosuccinate lyase
DJ476_RS29290	COG3973	AAA domain
DJ476_RS29305	COG0477	Major facilitator Superfamily
DJ476_RS29345	COG2011	ABC-type metal ion transport system permease component
DJ476_RS29350	COG1464	Belongs to the NlpA lipoprotein family
DJ476_RS29365	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DJ476_RS29370	COG1648	precorrin-2 dehydrogenase activity
DJ476_RS29370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DJ476_RS29425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DJ476_RS29480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DJ476_RS29495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DJ476_RS29520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DJ476_RS29525	COG1560	Kdo2-lipid A biosynthetic process
DJ476_RS29530	COG0438	transferase activity, transferring glycosyl groups
DJ476_RS29540	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DJ476_RS29545	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DJ476_RS29550	COG0217	transcriptional regulatory protein
DJ476_RS29555	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DJ476_RS29560	COG0632	four-way junction helicase activity
DJ476_RS29565	COG2255	four-way junction helicase activity
DJ476_RS29575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DJ476_RS29580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DJ476_RS29585	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DJ476_RS29590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DJ476_RS29595	COG1196	nuclear chromosome segregation
DJ476_RS29610	COG0124	histidyl-tRNA synthetase
DJ476_RS29630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DJ476_RS29650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DJ476_RS29655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DJ476_RS29670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DJ476_RS29675	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DJ476_RS29680	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DJ476_RS29685	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DJ476_RS29695	COG0006	proline dipeptidase activity
DJ476_RS29700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DJ476_RS29705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DJ476_RS29715	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DJ476_RS29720	COG0540	Belongs to the ATCase OTCase family
DJ476_RS29725	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DJ476_RS29735	COG0505	Belongs to the CarA family
DJ476_RS29740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DJ476_RS29745	COG0167	dihydroorotate dehydrogenase activity
DJ476_RS29750	COG0284	orotidine-5'-phosphate decarboxylase activity
DJ476_RS29765	COG1758	RNA polymerase activity
DJ476_RS29775	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DJ476_RS29790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DJ476_RS29800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DJ476_RS29805	COG2390	Transcriptional regulator
DJ476_RS29820	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS29830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DJ476_RS29845	COG2233	PERMEase
DJ476_RS29850	COG0738	Major facilitator superfamily
DJ476_RS29875	COG3201	nicotinamide mononucleotide transporter
DJ476_RS29885	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DJ476_RS29890	COG0140	phosphoribosyl-ATP diphosphatase activity
DJ476_RS29895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DJ476_RS29940	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS29965	COG1216	Glycosyl transferase, family 2
DJ476_RS29980	COG2270	Major facilitator Superfamily
DJ476_RS29990	COG2364	Membrane
DJ476_RS30065	COG2018	Roadblock/LC7 domain
DJ476_RS30095	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DJ476_RS30115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DJ476_RS30125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DJ476_RS30155	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DJ476_RS30175	COG1716	ATPase activity
DJ476_RS30195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DJ476_RS30205	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DJ476_RS30205	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DJ476_RS30250	COG1695	Transcriptional regulator
DJ476_RS30290	COG0697	spore germination
DJ476_RS30320	COG0583	DNA-binding transcription factor activity
DJ476_RS30380	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DJ476_RS30395	COG2318	DinB family
DJ476_RS30445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DJ476_RS30450	COG2226	methyltransferase
DJ476_RS30460	COG1968	undecaprenyl-diphosphatase activity
DJ476_RS30475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DJ476_RS30515	COG1832	CoA-binding protein
DJ476_RS30520	COG1739	Uncharacterized protein family UPF0029
DJ476_RS30525	COG0420	3'-5' exonuclease activity
DJ476_RS30530	COG0419	ATPase involved in DNA repair
DJ476_RS30550	COG0626	cystathionine gamma-synthase activity
DJ476_RS30580	COG1595	DNA-templated transcription, initiation
DJ476_RS30585	COG2188	Transcriptional regulator
DJ476_RS30590	COG1940	carbohydrate kinase activity
DJ476_RS30600	COG3663	DNA glycosylase
DJ476_RS30605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DJ476_RS30630	COG2226	methyltransferase
DJ476_RS30635	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DJ476_RS30640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DJ476_RS30645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DJ476_RS30650	COG0156	8-amino-7-oxononanoate synthase activity
DJ476_RS30695	COG0831	urea catabolic process
DJ476_RS30700	COG0832	Belongs to the urease beta subunit family
DJ476_RS30705	COG0804	urea catabolic process
DJ476_RS30715	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DJ476_RS30720	COG0829	nickel cation binding
DJ476_RS30735	COG0204	Acyl-transferase
DJ476_RS30750	COG0205	6-phosphofructokinase activity
DJ476_RS30755	COG3442	glutamine amidotransferase
DJ476_RS30765	COG0242	peptide deformylase activity
DJ476_RS30775	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS30780	COG0386	Belongs to the glutathione peroxidase family
DJ476_RS30795	COG1946	Acyl-CoA thioesterase
DJ476_RS30810	COG1793	dna ligase
DJ476_RS30815	COG1252	NADH dehydrogenase
DJ476_RS30830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DJ476_RS30830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DJ476_RS30855	COG1132	(ABC) transporter
DJ476_RS30860	COG1132	(ABC) transporter
DJ476_RS30870	COG0277	FAD linked oxidase domain protein
DJ476_RS30885	COG1132	(ABC) transporter
DJ476_RS30900	COG2072	flavoprotein involved in K transport
DJ476_RS30910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DJ476_RS30935	COG1501	Belongs to the glycosyl hydrolase 31 family
DJ476_RS30955	COG0395	ABC-type sugar transport system, permease component
DJ476_RS31000	COG1172	Belongs to the binding-protein-dependent transport system permease family
DJ476_RS31005	COG1172	Belongs to the binding-protein-dependent transport system permease family
DJ476_RS31015	COG1879	ABC-type sugar transport system periplasmic component
DJ476_RS31020	COG1609	Transcriptional regulator
DJ476_RS31035	COG2160	L-arabinose isomerase activity
DJ476_RS31040	COG3940	Belongs to the glycosyl hydrolase 43 family
DJ476_RS31050	COG3940	Belongs to the glycosyl hydrolase 43 family
DJ476_RS31080	COG4213	ABC transporter substrate-binding protein
DJ476_RS31090	COG4214	carbohydrate transport
DJ476_RS31115	COG1120	ATPase activity
DJ476_RS31130	COG0803	Belongs to the bacterial solute-binding protein 9 family
DJ476_RS31145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DJ476_RS31150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DJ476_RS31180	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS31180	COG1454	alcohol dehydrogenase
DJ476_RS31185	COG0516	GMP reductase activity
DJ476_RS31185	COG0517	IMP dehydrogenase activity
DJ476_RS31210	COG1017	nitric oxide dioxygenase activity
DJ476_RS31210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DJ476_RS31220	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DJ476_RS31275	COG0589	response to stress
DJ476_RS31285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DJ476_RS31285	COG4651	solute:proton antiporter activity
DJ476_RS31300	COG0589	response to stress
DJ476_RS31355	COG1191	sigma factor activity
DJ476_RS31390	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DJ476_RS31410	COG0583	DNA-binding transcription factor activity
DJ476_RS31435	COG0385	Bile acid
DJ476_RS31465	COG4592	Periplasmic binding protein
DJ476_RS31475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS31480	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS31495	COG0542	response to heat
DJ476_RS31500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DJ476_RS31555	COG1335	isochorismatase
DJ476_RS31570	COG2124	cytochrome p450
DJ476_RS31575	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS31650	COG1357	PFAM Pentapeptide repeats (8 copies)
DJ476_RS31675	COG0243	molybdopterin cofactor binding
DJ476_RS31695	COG0745	RESPONSE REGULATOR receiver
DJ476_RS31705	COG2835	tetraacyldisaccharide 4'-kinase activity
DJ476_RS31725	COG4981	capsule polysaccharide biosynthetic process
DJ476_RS31755	COG1012	belongs to the aldehyde dehydrogenase family
DJ476_RS31760	COG0174	glutamine synthetase
DJ476_RS31765	COG2186	Transcriptional regulator
DJ476_RS31770	COG0531	amino acid
DJ476_RS31775	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DJ476_RS31815	COG1253	flavin adenine dinucleotide binding
DJ476_RS31845	COG0667	Aldo Keto reductase
DJ476_RS31850	COG2815	serine threonine protein kinase
DJ476_RS31850	COG0515	serine threonine protein kinase
DJ476_RS31855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DJ476_RS31875	COG2706	6-phosphogluconolactonase activity
DJ476_RS31885	COG2971	BadF BadG BcrA BcrD
DJ476_RS31890	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DJ476_RS31915	COG2226	methyltransferase
DJ476_RS31940	COG0671	phosphoesterase, PA-phosphatase related
DJ476_RS31955	COG0456	acetyltransferase
DJ476_RS31960	COG0584	glycerophosphoryl diester phosphodiesterase
DJ476_RS32005	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DJ476_RS32030	COG1940	carbohydrate kinase activity
DJ476_RS32050	COG0445	tRNA wobble uridine modification
DJ476_RS32090	COG2223	nitrite transmembrane transporter activity
DJ476_RS32095	COG1940	carbohydrate kinase activity
DJ476_RS32135	COG0702	epimerase
DJ476_RS32150	COG1349	DNA-binding transcription factor activity
DJ476_RS32160	COG0464	growth
DJ476_RS32180	COG2045	Belongs to the ComB family
DJ476_RS32235	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DJ476_RS32290	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DJ476_RS32290	COG0515	serine threonine protein kinase
DJ476_RS32295	COG0515	serine threonine protein kinase
DJ476_RS32295	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DJ476_RS32305	COG1120	ATPase activity
DJ476_RS32330	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DJ476_RS32340	COG1132	(ABC) transporter
DJ476_RS32345	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS32350	COG0328	RNA-DNA hybrid ribonuclease activity
DJ476_RS32400	COG0842	Transport permease protein
DJ476_RS32400	COG1131	(ABC) transporter
DJ476_RS32400	COG1716	ATPase activity
DJ476_RS32445	COG2837	iron assimilation
DJ476_RS32475	COG1295	ribonuclease BN
DJ476_RS32475	COG1959	2 iron, 2 sulfur cluster binding
DJ476_RS32525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DJ476_RS32550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS32555	COG1120	ATPase activity
DJ476_RS32575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DJ476_RS32580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DJ476_RS32590	COG1191	sigma factor activity
DJ476_RS32620	COG0488	(ABC) transporter
DJ476_RS32635	COG1461	Dihydroxyacetone kinase
DJ476_RS32640	COG2376	Dihydroxyacetone kinase
DJ476_RS32650	COG0659	secondary active sulfate transmembrane transporter activity
DJ476_RS32655	COG0789	Transcriptional regulator
DJ476_RS32670	COG0492	ferredoxin-NADP+ reductase activity
DJ476_RS32675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DJ476_RS32685	COG0798	PFAM Bile acid sodium symporter
DJ476_RS32690	COG2072	flavoprotein involved in K transport
DJ476_RS32700	COG2072	flavoprotein involved in K transport
DJ476_RS32740	COG3842	ATPase activity
DJ476_RS32745	COG1178	ABC-type Fe3 transport system permease component
DJ476_RS32750	COG1840	ABC-type Fe3 transport system, periplasmic component
DJ476_RS32775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS32780	COG1120	ATPase activity
DJ476_RS32785	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DJ476_RS32790	COG1132	(ABC) transporter
DJ476_RS32800	COG1132	(ABC) transporter
DJ476_RS32805	COG2382	esterase
DJ476_RS32825	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DJ476_RS32855	COG1349	DNA-binding transcription factor activity
DJ476_RS32870	COG0395	ABC-type sugar transport system, permease component
DJ476_RS32875	COG1063	alcohol dehydrogenase
DJ476_RS32915	COG1470	cell adhesion involved in biofilm formation
DJ476_RS32945	COG3845	ABC transporter
DJ476_RS32980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DJ476_RS33000	COG3433	isochorismatase activity
DJ476_RS33000	COG1535	isochorismatase
DJ476_RS33005	COG1535	isochorismatase
DJ476_RS33005	COG3433	isochorismatase activity
DJ476_RS33010	COG1021	2,3-dihydroxybenzoate-AMP ligase
DJ476_RS33015	COG1169	isochorismate synthase
DJ476_RS33020	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS33025	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DJ476_RS33030	COG2382	esterase
DJ476_RS33035	COG0477	Major facilitator Superfamily
DJ476_RS33045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DJ476_RS33055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DJ476_RS33060	COG1120	ATPase activity
DJ476_RS33085	COG2365	Tyrosine phosphatase family
DJ476_RS33145	COG2080	2 iron, 2 sulfur cluster binding
DJ476_RS33150	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DJ476_RS33155	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DJ476_RS33170	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DJ476_RS33175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DJ476_RS33190	COG2066	Belongs to the glutaminase family
DJ476_RS33190	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DJ476_RS33195	COG2356	endonuclease I
DJ476_RS33210	COG2813	Specifically methylates the guanine in position
DJ476_RS33215	COG1960	acyl-CoA dehydrogenase activity
DJ476_RS33225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DJ476_RS33225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DJ476_RS33225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DJ476_RS33225	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DJ476_RS33225	COG3321	synthase
DJ476_RS33225	COG3321	synthase
DJ476_RS33225	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DJ476_RS33225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DJ476_RS33235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DJ476_RS33250	COG0346	lactoylglutathione lyase activity
DJ476_RS33255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DJ476_RS33270	COG0515	serine threonine protein kinase
DJ476_RS33280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DJ476_RS33285	COG2070	2-Nitropropane dioxygenase
DJ476_RS33295	COG2366	antibiotic biosynthetic process
DJ476_RS33300	COG0318	PFAM AMP-dependent synthetase and ligase
DJ476_RS33310	COG0765	amino acid transport
DJ476_RS33345	COG1024	Enoyl-CoA hydratase
DJ476_RS33405	COG0254	rRNA binding
DJ476_RS33475	COG1105	Belongs to the carbohydrate kinase PfkB family
DJ476_RS33480	COG1349	DNA-binding transcription factor activity
DJ476_RS33520	COG1653	transport
DJ476_RS33525	COG1175	transmembrane transport
DJ476_RS33530	COG0395	ABC-type sugar transport system, permease component
DJ476_RS33535	COG0366	Alpha amylase catalytic
DJ476_RS33540	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DJ476_RS33545	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
DJ476_RS33565	COG0642	Histidine kinase
DJ476_RS33595	COG0702	epimerase
DJ476_RS33610	COG1064	alcohol dehydrogenase
DJ476_RS33615	COG0640	Transcriptional regulator
DJ476_RS33620	COG1902	pentaerythritol trinitrate reductase activity
DJ476_RS33650	COG0789	Transcriptional regulator
DJ476_RS33655	COG1764	response to oxidative stress
DJ476_RS33660	COG1846	Transcriptional regulator
DJ476_RS33670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DJ476_RS33675	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DJ476_RS33755	COG1028	Short-chain dehydrogenase reductase Sdr
DJ476_RS33760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DJ476_RS33775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DJ476_RS33790	COG0477	Major facilitator Superfamily
DJ476_RS33795	COG0367	asparagine synthase
DJ476_RS33805	COG3328	transposase activity
DJ476_RS33865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DJ476_RS33870	COG0587	DNA-directed DNA polymerase activity
DJ476_RS33885	COG0640	Transcriptional regulator
DJ476_RS33900	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DJ476_RS33960	COG2801	Transposase and inactivated derivatives
DJ476_RS34135	COG0640	Transcriptional regulator
DJ476_RS34170	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DJ476_RS34220	COG2226	methyltransferase
DJ476_RS34230	COG1595	DNA-templated transcription, initiation
DJ476_RS34245	COG2801	Transposase and inactivated derivatives
DJ476_RS34250	COG2826	transposase and inactivated derivatives, IS30 family
DJ476_RS34280	COG1122	ATPase activity
DJ476_RS34315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair