locus-tag	class	description
NLU04_RS00005	COG3396	Phenylacetate-CoA oxygenase
NLU04_RS00010	COG3460	Phenylacetate-CoA oxygenase
NLU04_RS00015	COG3396	Phenylacetate-CoA oxygenase
NLU04_RS00020	COG2151	metal-sulfur cluster biosynthetic enzyme
NLU04_RS00025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NLU04_RS00030	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS00035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NLU04_RS00060	COG1716	ATPase activity
NLU04_RS00065	COG1716	ATPase activity
NLU04_RS00080	COG0768	penicillin binding
NLU04_RS00085	COG0515	serine threonine protein kinase
NLU04_RS00090	COG3764	Sortase (surface protein transpeptidase)
NLU04_RS00095	COG3764	Sortase (surface protein transpeptidase)
NLU04_RS00110	COG3764	Sortase (surface protein transpeptidase)
NLU04_RS00125	COG0705	Rhomboid family
NLU04_RS00155	COG0515	serine threonine protein kinase
NLU04_RS00190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLU04_RS00200	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
NLU04_RS00205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NLU04_RS00210	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NLU04_RS00215	COG0592	DNA-directed DNA polymerase activity
NLU04_RS00230	COG0594	ribonuclease P activity
NLU04_RS00235	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NLU04_RS00240	COG0706	membrane insertase activity
NLU04_RS00250	COG0357	Ribosomal RNA small subunit methyltransferase G
NLU04_RS00255	COG1192	Involved in chromosome partitioning
NLU04_RS00270	COG3118	belongs to the thioredoxin family
NLU04_RS00275	COG0492	ferredoxin-NADP+ reductase activity
NLU04_RS00285	COG1595	DNA-templated transcription, initiation
NLU04_RS00290	COG0515	serine threonine protein kinase
NLU04_RS00290	COG2815	serine threonine protein kinase
NLU04_RS00305	COG0617	tRNA 3'-terminal CCA addition
NLU04_RS00325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NLU04_RS00350	COG0360	Binds together with S18 to 16S ribosomal RNA
NLU04_RS00355	COG0629	single-stranded DNA binding
NLU04_RS00360	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NLU04_RS00365	COG0359	binds to the 23S rRNA
NLU04_RS00370	COG0534	Mate efflux family protein
NLU04_RS00375	COG0305	Participates in initiation and elongation during chromosome replication
NLU04_RS00405	COG2814	Major facilitator Superfamily
NLU04_RS00425	COG0626	cystathionine gamma-synthase activity
NLU04_RS00430	COG1950	PFAM Membrane protein of
NLU04_RS00435	COG0662	Cupin 2, conserved barrel domain protein
NLU04_RS00460	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NLU04_RS00465	COG3152	Membrane
NLU04_RS00475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NLU04_RS00480	COG1609	Transcriptional regulator
NLU04_RS00485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NLU04_RS00490	COG1271	oxidase subunit
NLU04_RS00495	COG1294	oxidase, subunit
NLU04_RS00500	COG4988	ABC transporter
NLU04_RS00510	COG0561	phosphatase activity
NLU04_RS00520	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NLU04_RS00525	COG0789	Transcriptional regulator
NLU04_RS00540	COG1131	(ABC) transporter
NLU04_RS00565	COG0561	phosphatase activity
NLU04_RS00570	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NLU04_RS00575	COG0077	Prephenate dehydratase
NLU04_RS00580	COG2837	iron assimilation
NLU04_RS00585	COG2372	response to copper ion
NLU04_RS00595	COG1999	signal sequence binding
NLU04_RS00615	COG0006	proline dipeptidase activity
NLU04_RS00635	COG0653	protein targeting
NLU04_RS00650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NLU04_RS00675	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS00700	COG1595	DNA-templated transcription, initiation
NLU04_RS00705	COG0318	PFAM AMP-dependent synthetase and ligase
NLU04_RS00785	COG2186	Transcriptional regulator
NLU04_RS00835	COG0745	RESPONSE REGULATOR receiver
NLU04_RS00840	COG2205	protein histidine kinase activity
NLU04_RS00850	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NLU04_RS00865	COG0477	Major facilitator Superfamily
NLU04_RS00880	COG3467	pyridoxamine 5'-phosphate
NLU04_RS00885	COG2353	YceI-like domain
NLU04_RS00895	COG1846	Transcriptional regulator
NLU04_RS00910	COG1191	sigma factor activity
NLU04_RS00915	COG1191	sigma factor activity
NLU04_RS00940	COG1518	maintenance of DNA repeat elements
NLU04_RS01020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NLU04_RS01100	COG1476	TRANSCRIPTIONal
NLU04_RS01110	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NLU04_RS01145	COG2815	serine threonine protein kinase
NLU04_RS01145	COG0515	serine threonine protein kinase
NLU04_RS01150	COG0492	ferredoxin-NADP+ reductase activity
NLU04_RS01200	COG0151	Belongs to the GarS family
NLU04_RS01215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NLU04_RS01225	COG2197	response regulator
NLU04_RS01245	COG1131	(ABC) transporter
NLU04_RS01265	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLU04_RS01270	COG0047	phosphoribosylformylglycinamidine synthase activity
NLU04_RS01275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLU04_RS01285	COG0741	lytic transglycosylase activity
NLU04_RS01285	COG0739	heme binding
NLU04_RS01285	COG1196	nuclear chromosome segregation
NLU04_RS01290	COG2318	DinB family
NLU04_RS01305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NLU04_RS01340	COG1643	Atp-dependent helicase
NLU04_RS01350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NLU04_RS01350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NLU04_RS01355	COG0785	Cytochrome C biogenesis protein
NLU04_RS01385	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLU04_RS01390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLU04_RS01400	COG0513	Belongs to the DEAD box helicase family
NLU04_RS01425	COG0789	Transcriptional regulator
NLU04_RS01435	COG0739	heme binding
NLU04_RS01435	COG1196	nuclear chromosome segregation
NLU04_RS01435	COG0741	lytic transglycosylase activity
NLU04_RS01445	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NLU04_RS01450	COG0579	oxidoreductase
NLU04_RS01475	COG1252	NADH dehydrogenase
NLU04_RS01490	COG1846	Transcriptional regulator
NLU04_RS01560	COG1196	nuclear chromosome segregation
NLU04_RS01560	COG0741	lytic transglycosylase activity
NLU04_RS01560	COG0739	heme binding
NLU04_RS01565	COG0671	phosphoesterase, PA-phosphatase related
NLU04_RS01585	COG1937	Protein conserved in bacteria
NLU04_RS01595	COG0306	phosphate transporter
NLU04_RS01615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NLU04_RS01620	COG0406	alpha-ribazole phosphatase activity
NLU04_RS01620	COG0494	nUDIX hydrolase
NLU04_RS01640	COG1116	anion transmembrane transporter activity
NLU04_RS01645	COG1725	Transcriptional regulator
NLU04_RS01655	COG0456	acetyltransferase
NLU04_RS01675	COG0737	Belongs to the 5'-nucleotidase family
NLU04_RS01740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NLU04_RS01745	COG1609	Transcriptional regulator
NLU04_RS01750	COG0745	RESPONSE REGULATOR receiver
NLU04_RS01775	COG2897	thiosulfate sulfurtransferase activity
NLU04_RS01810	COG3485	protocatechuate 3,4-dioxygenase
NLU04_RS01815	COG0735	belongs to the Fur family
NLU04_RS01825	COG1490	D-aminoacyl-tRNA deacylase activity
NLU04_RS01840	COG4552	Acetyltransferase involved in intracellular survival and related
NLU04_RS01900	COG0475	glutathione-regulated potassium exporter activity
NLU04_RS01930	COG4770	biotin carboxylase activity
NLU04_RS01955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NLU04_RS01985	COG0736	holo-[acyl-carrier-protein] synthase activity
NLU04_RS01990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NLU04_RS02015	COG2318	DinB family
NLU04_RS02025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLU04_RS02065	COG0438	transferase activity, transferring glycosyl groups
NLU04_RS02100	COG0588	phosphoglycerate mutase activity
NLU04_RS02120	COG5002	protein histidine kinase activity
NLU04_RS02135	COG1329	Transcriptional regulator
NLU04_RS02140	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NLU04_RS02145	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NLU04_RS02155	COG0215	cysteine-tRNA ligase activity
NLU04_RS02170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NLU04_RS02180	COG3842	ATPase activity
NLU04_RS02205	COG0745	RESPONSE REGULATOR receiver
NLU04_RS02245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NLU04_RS02285	COG2197	response regulator
NLU04_RS02290	COG4585	Histidine kinase
NLU04_RS02300	COG0666	response to abiotic stimulus
NLU04_RS02325	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NLU04_RS02345	COG1105	Belongs to the carbohydrate kinase PfkB family
NLU04_RS02350	COG2801	Transposase and inactivated derivatives
NLU04_RS02350	COG3415	Transposase
NLU04_RS02360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NLU04_RS02380	COG1877	trehalose-phosphatase activity
NLU04_RS02380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NLU04_RS02385	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NLU04_RS02390	COG0463	Glycosyl transferase, family 2
NLU04_RS02440	COG1132	(ABC) transporter
NLU04_RS02455	COG1595	DNA-templated transcription, initiation
NLU04_RS02485	COG0395	ABC-type sugar transport system, permease component
NLU04_RS02490	COG1175	transmembrane transport
NLU04_RS02525	COG4251	negative regulation of phosphorylation
NLU04_RS02530	COG2197	response regulator
NLU04_RS02555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NLU04_RS02555	COG1263	PTS System
NLU04_RS02560	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NLU04_RS02565	COG1737	Transcriptional regulator
NLU04_RS02600	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NLU04_RS02605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NLU04_RS02610	COG1984	allophanate hydrolase subunit 2
NLU04_RS02620	COG3142	Participates in the control of copper homeostasis
NLU04_RS02625	COG3973	AAA domain
NLU04_RS02645	COG1061	Type III restriction enzyme res subunit
NLU04_RS02650	COG1846	Transcriptional regulator
NLU04_RS02675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NLU04_RS02680	COG1120	ATPase activity
NLU04_RS02685	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS02690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS02715	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NLU04_RS02720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NLU04_RS02730	COG2814	Major facilitator Superfamily
NLU04_RS02745	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NLU04_RS02755	COG2252	PERMEase
NLU04_RS02790	COG0667	Aldo Keto reductase
NLU04_RS02795	COG2267	carboxylic ester hydrolase activity
NLU04_RS02805	COG0515	serine threonine protein kinase
NLU04_RS02810	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS02815	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS02820	COG0583	DNA-binding transcription factor activity
NLU04_RS02895	COG1051	belongs to the nudix hydrolase family
NLU04_RS02915	COG1309	transcriptional regulator
NLU04_RS02925	COG0697	spore germination
NLU04_RS02980	COG1335	isochorismatase
NLU04_RS03015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NLU04_RS03045	COG2205	protein histidine kinase activity
NLU04_RS03050	COG0247	lactate metabolic process
NLU04_RS03050	COG0277	FAD linked oxidase domain protein
NLU04_RS03055	COG3896	Chloramphenicol phosphotransferase-like protein
NLU04_RS03065	COG0583	DNA-binding transcription factor activity
NLU04_RS03070	COG5006	permease, DMT superfamily
NLU04_RS03080	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
NLU04_RS03100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NLU04_RS03115	COG0318	PFAM AMP-dependent synthetase and ligase
NLU04_RS03120	COG1024	Enoyl-CoA hydratase
NLU04_RS03205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NLU04_RS03220	COG2124	cytochrome p450
NLU04_RS03245	COG0259	pyridoxamine-phosphate oxidase activity
NLU04_RS03255	COG1136	(ABC) transporter
NLU04_RS03255	COG0577	efflux transmembrane transporter activity
NLU04_RS03260	COG2205	protein histidine kinase activity
NLU04_RS03265	COG4821	SIS domain
NLU04_RS03275	COG2267	carboxylic ester hydrolase activity
NLU04_RS03305	COG0477	Major facilitator Superfamily
NLU04_RS03320	COG1595	DNA-templated transcription, initiation
NLU04_RS03385	COG0318	PFAM AMP-dependent synthetase and ligase
NLU04_RS03395	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS03400	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS03415	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS03420	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS03520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NLU04_RS03550	COG1024	Enoyl-CoA hydratase
NLU04_RS03575	COG2072	flavoprotein involved in K transport
NLU04_RS03580	COG4592	Periplasmic binding protein
NLU04_RS03585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS03590	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS03620	COG0501	Belongs to the peptidase M48B family
NLU04_RS03625	COG0259	pyridoxamine-phosphate oxidase activity
NLU04_RS03635	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS03645	COG1309	transcriptional regulator
NLU04_RS03670	COG1024	Enoyl-CoA hydratase
NLU04_RS03710	COG1278	Cold shock
NLU04_RS03715	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NLU04_RS03725	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NLU04_RS03735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NLU04_RS03740	COG4521	taurine ABC transporter
NLU04_RS03750	COG2175	clavaminate synthase activity
NLU04_RS03755	COG2226	methyltransferase
NLU04_RS03820	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NLU04_RS03825	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NLU04_RS03830	COG0649	NAD binding
NLU04_RS03840	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NLU04_RS03845	COG1034	ATP synthesis coupled electron transport
NLU04_RS03850	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NLU04_RS03855	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NLU04_RS03860	COG0839	Belongs to the complex I subunit 6 family
NLU04_RS03865	COG0713	ATP synthesis coupled electron transport
NLU04_RS03870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NLU04_RS03880	COG1007	ATP synthesis coupled electron transport
NLU04_RS03885	COG0514	ATP-dependent DNA helicase (RecQ)
NLU04_RS03910	COG3104	oligopeptide transport
NLU04_RS03915	COG0142	geranyltranstransferase activity
NLU04_RS03925	COG1131	(ABC) transporter
NLU04_RS03950	COG0561	phosphatase activity
NLU04_RS03990	COG0702	epimerase
NLU04_RS03995	COG1733	regulation of RNA biosynthetic process
NLU04_RS04000	COG1013	pyruvate-flavodoxin oxidoreductase activity
NLU04_RS04005	COG0674	pyruvate-flavodoxin oxidoreductase activity
NLU04_RS04005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NLU04_RS04025	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NLU04_RS04030	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NLU04_RS04035	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NLU04_RS04040	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NLU04_RS04045	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NLU04_RS04050	COG0839	Belongs to the complex I subunit 6 family
NLU04_RS04055	COG0713	ATP synthesis coupled electron transport
NLU04_RS04060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NLU04_RS04070	COG1007	ATP synthesis coupled electron transport
NLU04_RS04075	COG1970	mechanosensitive ion channel activity
NLU04_RS04080	COG0501	Belongs to the peptidase M48B family
NLU04_RS04085	COG3304	Inner membrane component domain
NLU04_RS04090	COG2261	transglycosylase associated protein
NLU04_RS04100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NLU04_RS04105	COG1666	GTP binding
NLU04_RS04135	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NLU04_RS04140	COG2030	dehydratase
NLU04_RS04150	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NLU04_RS04165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NLU04_RS04170	COG0436	Aminotransferase
NLU04_RS04190	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NLU04_RS04195	COG0081	regulation of translation
NLU04_RS04200	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NLU04_RS04205	COG0222	ribosome binding
NLU04_RS04210	COG0085	RNA polymerase activity
NLU04_RS04215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLU04_RS04320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NLU04_RS04325	COG0049	tRNA binding
NLU04_RS04330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NLU04_RS04335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NLU04_RS04360	COG0051	transcription antitermination factor activity, RNA binding
NLU04_RS04365	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NLU04_RS04370	COG0088	Forms part of the polypeptide exit tunnel
NLU04_RS04375	COG0089	rRNA binding
NLU04_RS04380	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NLU04_RS04385	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NLU04_RS04390	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NLU04_RS04395	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NLU04_RS04400	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NLU04_RS04405	COG0255	Belongs to the universal ribosomal protein uL29 family
NLU04_RS04410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NLU04_RS04415	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NLU04_RS04420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NLU04_RS04425	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NLU04_RS04430	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLU04_RS04435	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NLU04_RS04440	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NLU04_RS04445	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NLU04_RS04450	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NLU04_RS04455	COG1841	ribosomal large subunit assembly
NLU04_RS04460	COG0200	Binds to the 23S rRNA
NLU04_RS04470	COG0563	adenylate kinase activity
NLU04_RS04480	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NLU04_RS04485	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NLU04_RS04490	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NLU04_RS04495	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NLU04_RS04500	COG0202	RNA polymerase activity
NLU04_RS04505	COG0203	ribosomal protein L17
NLU04_RS04510	COG0101	tRNA pseudouridine synthase activity
NLU04_RS04535	COG0488	(ABC) transporter
NLU04_RS04540	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NLU04_RS04545	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NLU04_RS04550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NLU04_RS04560	COG1072	(Pantothenic acid kinase))
NLU04_RS04575	COG4566	intracellular signal transduction
NLU04_RS04585	COG0747	negative chemotaxis
NLU04_RS04590	COG3795	YCII-related domain
NLU04_RS04595	COG4941	Belongs to the sigma-70 factor family
NLU04_RS04620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NLU04_RS04625	COG0736	holo-[acyl-carrier-protein] synthase activity
NLU04_RS04635	COG3189	MarR family transcriptional regulator
NLU04_RS04640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NLU04_RS04650	COG0802	atpase or kinase
NLU04_RS04675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NLU04_RS04710	COG0726	polysaccharide deacetylase
NLU04_RS04715	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NLU04_RS04725	COG4221	oxidoreductase activity
NLU04_RS04735	COG0583	DNA-binding transcription factor activity
NLU04_RS04745	COG2197	response regulator
NLU04_RS04750	COG1595	DNA-templated transcription, initiation
NLU04_RS04760	COG0516	GMP reductase activity
NLU04_RS04775	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NLU04_RS04790	COG0515	serine threonine protein kinase
NLU04_RS04795	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS04815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NLU04_RS04815	COG0519	Catalyzes the synthesis of GMP from XMP
NLU04_RS04855	COG2197	response regulator
NLU04_RS04890	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NLU04_RS04890	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NLU04_RS04910	COG0714	Associated with various cellular activities
NLU04_RS04915	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NLU04_RS04920	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NLU04_RS04925	COG0045	succinate-CoA ligase (ADP-forming) activity
NLU04_RS04955	COG0138	bifunctional purine biosynthesis protein purh
NLU04_RS04970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NLU04_RS04985	COG0039	L-malate dehydrogenase activity
NLU04_RS04990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NLU04_RS04995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NLU04_RS05005	COG0754	glutathionylspermidine amidase activity
NLU04_RS05010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NLU04_RS05015	COG0180	Tryptophanyl-tRNA synthetase
NLU04_RS05035	COG1295	ribonuclease BN
NLU04_RS05040	COG1686	Belongs to the peptidase S11 family
NLU04_RS05050	COG1408	metallophosphoesterase
NLU04_RS05080	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NLU04_RS05085	COG1053	succinate dehydrogenase
NLU04_RS05095	COG2009	succinate dehydrogenase
NLU04_RS05140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NLU04_RS05160	COG1595	DNA-templated transcription, initiation
NLU04_RS05185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NLU04_RS05195	COG1216	Glycosyl transferase, family 2
NLU04_RS05215	COG1083	cytidylyl-transferase
NLU04_RS05220	COG2089	acid synthase
NLU04_RS05230	COG1473	amidohydrolase
NLU04_RS05230	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NLU04_RS05235	COG1744	ABC transporter substrate-binding protein PnrA-like
NLU04_RS05240	COG3845	ABC transporter
NLU04_RS05245	COG4603	Belongs to the binding-protein-dependent transport system permease family
NLU04_RS05250	COG1079	Belongs to the binding-protein-dependent transport system permease family
NLU04_RS05270	COG1404	Belongs to the peptidase S8 family
NLU04_RS05290	COG2814	Major facilitator Superfamily
NLU04_RS05295	COG0583	DNA-binding transcription factor activity
NLU04_RS05310	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NLU04_RS05335	COG2205	protein histidine kinase activity
NLU04_RS05340	COG0745	RESPONSE REGULATOR receiver
NLU04_RS05345	COG1595	DNA-templated transcription, initiation
NLU04_RS05375	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS05380	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS05395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NLU04_RS05415	COG1349	DNA-binding transcription factor activity
NLU04_RS05425	COG4770	biotin carboxylase activity
NLU04_RS05435	COG0424	maF-like protein
NLU04_RS05450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NLU04_RS05465	COG1024	Enoyl-CoA hydratase
NLU04_RS05490	COG1376	ErfK ybiS ycfS ynhG family protein
NLU04_RS05510	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NLU04_RS05515	COG1396	sequence-specific DNA binding
NLU04_RS05530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLU04_RS05550	COG1595	DNA-templated transcription, initiation
NLU04_RS05560	COG2205	protein histidine kinase activity
NLU04_RS05560	COG2202	Pas domain
NLU04_RS05570	COG2172	sigma factor antagonist activity
NLU04_RS05575	COG1366	Belongs to the anti-sigma-factor antagonist family
NLU04_RS05580	COG1366	Belongs to the anti-sigma-factor antagonist family
NLU04_RS05585	COG2255	four-way junction helicase activity
NLU04_RS05590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NLU04_RS05605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NLU04_RS05615	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NLU04_RS05670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NLU04_RS05680	COG0798	PFAM Bile acid sodium symporter
NLU04_RS05685	COG2072	flavoprotein involved in K transport
NLU04_RS05700	COG0492	ferredoxin-NADP+ reductase activity
NLU04_RS05705	COG0640	Transcriptional regulator
NLU04_RS05735	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NLU04_RS05835	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NLU04_RS05850	COG1414	Transcriptional regulator
NLU04_RS05855	COG0251	oxidation-reduction process
NLU04_RS05860	COG2610	gluconate transmembrane transporter activity
NLU04_RS05885	COG2894	cell division
NLU04_RS05915	COG3920	Histidine kinase
NLU04_RS05920	COG2197	response regulator
NLU04_RS05940	COG2885	chlorophyll binding
NLU04_RS05995	COG0667	Aldo Keto reductase
NLU04_RS06000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NLU04_RS06005	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NLU04_RS06020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NLU04_RS06025	COG0450	alkyl hydroperoxide reductase
NLU04_RS06040	COG1136	(ABC) transporter
NLU04_RS06060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NLU04_RS06060	COG4499	WXG100 protein secretion system (Wss), protein YukC
NLU04_RS06075	COG0114	fumarate hydratase activity
NLU04_RS06085	COG1362	aminopeptidase activity
NLU04_RS06090	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NLU04_RS06090	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NLU04_RS06115	COG0778	Nitroreductase
NLU04_RS06120	COG1722	exodeoxyribonuclease VII activity
NLU04_RS06125	COG1570	exodeoxyribonuclease VII activity
NLU04_RS06135	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NLU04_RS06150	COG0012	GTP binding
NLU04_RS06180	COG0789	Transcriptional regulator
NLU04_RS06220	COG1842	Phage shock protein A
NLU04_RS06230	COG0463	Glycosyl transferase, family 2
NLU04_RS06240	COG4941	Belongs to the sigma-70 factor family
NLU04_RS06245	COG3795	YCII-related domain
NLU04_RS06280	COG0148	phosphopyruvate hydratase activity
NLU04_RS06300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NLU04_RS06305	COG2226	methyltransferase
NLU04_RS06315	COG1217	gtp-binding protein TYPA
NLU04_RS06325	COG0747	negative chemotaxis
NLU04_RS06330	COG0601	transmembrane transport
NLU04_RS06335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLU04_RS06345	COG4608	Belongs to the ABC transporter superfamily
NLU04_RS06350	COG4166	transmembrane transport
NLU04_RS06355	COG0601	transmembrane transport
NLU04_RS06360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLU04_RS06370	COG4608	Belongs to the ABC transporter superfamily
NLU04_RS06375	COG2197	response regulator
NLU04_RS06390	COG1136	(ABC) transporter
NLU04_RS06390	COG0577	efflux transmembrane transporter activity
NLU04_RS06420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NLU04_RS06450	COG0110	maltose O-acetyltransferase activity
NLU04_RS06460	COG0515	serine threonine protein kinase
NLU04_RS06470	COG1132	(ABC) transporter
NLU04_RS06475	COG1132	(ABC) transporter
NLU04_RS06480	COG2197	response regulator
NLU04_RS06485	COG2912	Transglutaminase-like superfamily
NLU04_RS06515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NLU04_RS06520	COG1611	Belongs to the LOG family
NLU04_RS06525	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NLU04_RS06535	COG0519	Catalyzes the synthesis of GMP from XMP
NLU04_RS06540	COG1024	Enoyl-CoA hydratase
NLU04_RS06555	COG1595	DNA-templated transcription, initiation
NLU04_RS06565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NLU04_RS06570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NLU04_RS06605	COG0598	Magnesium transport protein CorA
NLU04_RS06625	COG2095	MarC family integral membrane protein
NLU04_RS06635	COG1432	Conserved Protein
NLU04_RS06650	COG0513	Belongs to the DEAD box helicase family
NLU04_RS06690	COG0747	negative chemotaxis
NLU04_RS06695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLU04_RS06700	COG0601	transmembrane transport
NLU04_RS06705	COG4172	Belongs to the ABC transporter superfamily
NLU04_RS06760	COG0210	DNA helicase
NLU04_RS06805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NLU04_RS06855	COG3480	Lon protease (S16) C-terminal proteolytic domain
NLU04_RS06865	COG1615	UPF0182 protein
NLU04_RS06890	COG0753	catalase activity
NLU04_RS06900	COG0483	inositol monophosphate 1-phosphatase activity
NLU04_RS06910	COG2076	Multidrug Resistance protein
NLU04_RS06915	COG1162	GTPase activity
NLU04_RS06920	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NLU04_RS06930	COG2135	peptidase activity
NLU04_RS06940	COG1595	DNA-templated transcription, initiation
NLU04_RS06945	COG5662	AntiSigma factor
NLU04_RS06955	COG0242	peptide deformylase activity
NLU04_RS07060	COG1966	Carbon starvation protein
NLU04_RS07070	COG2182	Extracellular solute-binding protein
NLU04_RS07075	COG1175	transmembrane transport
NLU04_RS07080	COG0395	ABC-type sugar transport system, permease component
NLU04_RS07085	COG1472	Belongs to the glycosyl hydrolase 3 family
NLU04_RS07090	COG0363	glucosamine-6-phosphate deaminase activity
NLU04_RS07095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NLU04_RS07100	COG2801	Transposase and inactivated derivatives
NLU04_RS07100	COG3415	Transposase
NLU04_RS07115	COG1597	lipid kinase activity
NLU04_RS07130	COG2172	sigma factor antagonist activity
NLU04_RS07180	COG1959	2 iron, 2 sulfur cluster binding
NLU04_RS07185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NLU04_RS07190	COG0142	geranyltranstransferase activity
NLU04_RS07270	COG4106	trans-aconitate 2-methyltransferase activity
NLU04_RS07275	COG1126	abc transporter atp-binding protein
NLU04_RS07280	COG0765	amino acid transport
NLU04_RS07285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NLU04_RS07290	COG0281	malic enzyme
NLU04_RS07295	COG0604	alcohol dehydrogenase
NLU04_RS07315	COG0542	response to heat
NLU04_RS07340	COG0508	dehydrogenase complex catalyzes the overall conversion of
NLU04_RS07340	COG0567	Dehydrogenase, E1 component
NLU04_RS07345	COG2205	protein histidine kinase activity
NLU04_RS07350	COG0745	RESPONSE REGULATOR receiver
NLU04_RS07375	COG1131	(ABC) transporter
NLU04_RS07385	COG1595	DNA-templated transcription, initiation
NLU04_RS07390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NLU04_RS07395	COG0726	polysaccharide deacetylase
NLU04_RS07470	COG0791	NLP P60 protein
NLU04_RS07470	COG3883	PFAM NLP P60 protein
NLU04_RS07485	COG1309	transcriptional regulator
NLU04_RS07515	COG0768	penicillin binding
NLU04_RS07530	COG2205	protein histidine kinase activity
NLU04_RS07550	COG3285	dna ligase
NLU04_RS07550	COG1793	dna ligase
NLU04_RS07555	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NLU04_RS07580	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NLU04_RS07595	COG2815	serine threonine protein kinase
NLU04_RS07595	COG0515	serine threonine protein kinase
NLU04_RS07605	COG0210	DNA helicase
NLU04_RS07640	COG0018	arginyl-trna synthetase
NLU04_RS07645	COG0019	diaminopimelate decarboxylase activity
NLU04_RS07650	COG0460	homoserine dehydrogenase
NLU04_RS07655	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NLU04_RS07660	COG0083	homoserine kinase activity
NLU04_RS07670	COG1316	TRANSCRIPTIONal
NLU04_RS07675	COG0254	rRNA binding
NLU04_RS07680	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NLU04_RS07685	COG2890	protein-(glutamine-N5) methyltransferase activity
NLU04_RS07695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NLU04_RS07710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NLU04_RS07715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLU04_RS07730	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLU04_RS07735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NLU04_RS07740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLU04_RS07745	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NLU04_RS07750	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NLU04_RS07755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NLU04_RS07760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NLU04_RS07775	COG2197	response regulator
NLU04_RS07780	COG3850	Histidine kinase
NLU04_RS07790	COG2801	Transposase and inactivated derivatives
NLU04_RS07790	COG3415	Transposase
NLU04_RS07800	COG1250	3-hydroxyacyl-CoA dehydrogenase
NLU04_RS07815	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NLU04_RS07870	COG0183	Belongs to the thiolase family
NLU04_RS07885	COG4104	PAAR repeat-containing protein
NLU04_RS07885	COG3209	COG3209 Rhs family protein
NLU04_RS07905	COG0745	RESPONSE REGULATOR receiver
NLU04_RS07910	COG5002	protein histidine kinase activity
NLU04_RS07985	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NLU04_RS07985	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NLU04_RS07990	COG1597	lipid kinase activity
NLU04_RS08025	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLU04_RS08030	COG0280	phosphate acetyltransferase
NLU04_RS08030	COG0857	belongs to the CobB CobQ family
NLU04_RS08035	COG0205	6-phosphofructokinase activity
NLU04_RS08045	COG3415	Transposase
NLU04_RS08045	COG2801	Transposase and inactivated derivatives
NLU04_RS08055	COG4565	transcriptional regulatory protein
NLU04_RS08060	COG3290	protein histidine kinase activity
NLU04_RS08065	COG1301	dicarboxylic acid transport
NLU04_RS08070	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NLU04_RS08075	COG3281	Trehalose synthase
NLU04_RS08080	COG0366	Alpha amylase catalytic
NLU04_RS08085	COG0366	Alpha amylase catalytic
NLU04_RS08090	COG0058	SHG alpha-glucan phosphorylase activity
NLU04_RS08115	COG1132	(ABC) transporter
NLU04_RS08120	COG1132	(ABC) transporter
NLU04_RS08140	COG2197	response regulator
NLU04_RS08160	COG1024	Enoyl-CoA hydratase
NLU04_RS08185	COG3415	Transposase
NLU04_RS08185	COG2801	Transposase and inactivated derivatives
NLU04_RS08215	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NLU04_RS08220	COG0142	geranyltranstransferase activity
NLU04_RS08225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NLU04_RS08230	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NLU04_RS08270	COG0477	Major facilitator Superfamily
NLU04_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS08400	COG0823	Involved in the tonB-independent uptake of proteins
NLU04_RS08410	COG1222	aaa ATPase
NLU04_RS08435	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS08450	COG2235	arginine
NLU04_RS08475	COG1760	l-serine dehydratase
NLU04_RS08480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NLU04_RS08485	COG0509	glycine decarboxylation via glycine cleavage system
NLU04_RS08490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NLU04_RS08510	COG4166	transmembrane transport
NLU04_RS08515	COG0601	transmembrane transport
NLU04_RS08520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLU04_RS08530	COG4608	Belongs to the ABC transporter superfamily
NLU04_RS08535	COG2860	membrane
NLU04_RS08570	COG0482	sulfurtransferase activity
NLU04_RS08590	COG4221	oxidoreductase activity
NLU04_RS08600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NLU04_RS08610	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLU04_RS08615	COG0154	amidase activity
NLU04_RS08625	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLU04_RS08630	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NLU04_RS08640	COG2409	Drug exporters of the RND superfamily
NLU04_RS08655	COG2133	pyrroloquinoline quinone binding
NLU04_RS08660	COG0667	Aldo Keto reductase
NLU04_RS08680	COG0440	acetolactate synthase activity
NLU04_RS08685	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NLU04_RS08690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NLU04_RS08715	COG2508	Transcriptional regulator
NLU04_RS08720	COG0506	proline dehydrogenase activity
NLU04_RS08725	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS08740	COG2130	NADP-dependent
NLU04_RS08755	COG0473	3-isopropylmalate dehydrogenase activity
NLU04_RS08760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NLU04_RS08765	COG2957	Belongs to the agmatine deiminase family
NLU04_RS08775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NLU04_RS08790	COG4608	Belongs to the ABC transporter superfamily
NLU04_RS08795	COG0601	transmembrane transport
NLU04_RS08800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLU04_RS08805	COG0444	Belongs to the ABC transporter superfamily
NLU04_RS08815	COG1472	Belongs to the glycosyl hydrolase 3 family
NLU04_RS08835	COG2207	Transcriptional regulator
NLU04_RS08835	COG3708	Transcriptional regulator
NLU04_RS08855	COG0492	ferredoxin-NADP+ reductase activity
NLU04_RS08875	COG1733	regulation of RNA biosynthetic process
NLU04_RS08900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS08905	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS08910	COG1120	ATPase activity
NLU04_RS08915	COG4607	ABC-type enterochelin transport system periplasmic component
NLU04_RS08940	COG1470	cell adhesion involved in biofilm formation
NLU04_RS08940	COG0366	Alpha amylase catalytic
NLU04_RS08945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NLU04_RS08965	COG2018	Roadblock/LC7 domain
NLU04_RS08985	COG2018	Roadblock/LC7 domain
NLU04_RS08990	COG5002	protein histidine kinase activity
NLU04_RS09000	COG0179	Fumarylacetoacetate (FAA) hydrolase
NLU04_RS09005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NLU04_RS09040	COG1414	Transcriptional regulator
NLU04_RS09045	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NLU04_RS09050	COG0066	3-isopropylmalate dehydratase activity
NLU04_RS09060	COG0776	regulation of translation
NLU04_RS09070	COG1920	GTP binding
NLU04_RS09080	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NLU04_RS09085	COG1181	Belongs to the D-alanine--D-alanine ligase family
NLU04_RS09100	COG0351	phosphomethylpyrimidine kinase
NLU04_RS09105	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NLU04_RS09110	COG1461	Dihydroxyacetone kinase
NLU04_RS09115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NLU04_RS09120	COG0742	ribosomal rna small subunit methyltransferase
NLU04_RS09125	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NLU04_RS09140	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NLU04_RS09145	COG0571	ribonuclease III activity
NLU04_RS09150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NLU04_RS09155	COG1733	regulation of RNA biosynthetic process
NLU04_RS09160	COG2340	Cysteine-rich secretory protein family
NLU04_RS09165	COG1254	Belongs to the acylphosphatase family
NLU04_RS09175	COG1196	nuclear chromosome segregation
NLU04_RS09180	COG0477	Major facilitator Superfamily
NLU04_RS09215	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NLU04_RS09235	COG0228	four-way junction DNA binding
NLU04_RS09240	COG1837	Belongs to the UPF0109 family
NLU04_RS09245	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NLU04_RS09250	COG0336	Belongs to the RNA methyltransferase TrmD family
NLU04_RS09255	COG0335	large ribosomal subunit rRNA binding
NLU04_RS09270	COG0681	Belongs to the peptidase S26 family
NLU04_RS09275	COG0681	Belongs to the peptidase S26 family
NLU04_RS09290	COG0792	nuclease activity
NLU04_RS09305	COG1191	sigma factor activity
NLU04_RS09320	COG0052	Belongs to the universal ribosomal protein uS2 family
NLU04_RS09325	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NLU04_RS09330	COG0528	UMP kinase activity
NLU04_RS09335	COG0233	cytoplasmic translational termination
NLU04_RS09345	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NLU04_RS09360	COG3842	ATPase activity
NLU04_RS09375	COG1136	(ABC) transporter
NLU04_RS09380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NLU04_RS09390	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS09415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NLU04_RS09435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NLU04_RS09440	COG3842	ATPase activity
NLU04_RS09445	COG1176	ABC-type spermidine putrescine transport system, permease component I
NLU04_RS09450	COG1177	transmembrane transport
NLU04_RS09455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NLU04_RS09485	COG2508	Transcriptional regulator
NLU04_RS09490	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS09500	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NLU04_RS09505	COG0750	zinc metalloprotease
NLU04_RS09510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NLU04_RS09525	COG0442	prolyl-tRNA aminoacylation
NLU04_RS09545	COG0779	Required for maturation of 30S ribosomal subunits
NLU04_RS09560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NLU04_RS09570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NLU04_RS09575	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NLU04_RS09620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLU04_RS09625	COG0601	transmembrane transport
NLU04_RS09630	COG0747	negative chemotaxis
NLU04_RS09635	COG0455	bacterial-type flagellum organization
NLU04_RS09655	COG3266	domain, Protein
NLU04_RS09660	COG1404	Belongs to the peptidase S8 family
NLU04_RS09690	COG1674	ftsk spoiiie
NLU04_RS09700	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NLU04_RS09705	COG1185	polyribonucleotide nucleotidyltransferase activity
NLU04_RS09710	COG0612	Peptidase, M16
NLU04_RS09715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NLU04_RS09735	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
NLU04_RS09740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLU04_RS09745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLU04_RS09770	COG2770	Histidine kinase
NLU04_RS09770	COG2208	phosphoserine phosphatase activity
NLU04_RS09785	COG1674	ftsk spoiiie
NLU04_RS09795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NLU04_RS09805	COG1058	Belongs to the CinA family
NLU04_RS09805	COG1546	Belongs to the CinA family
NLU04_RS09810	COG1396	sequence-specific DNA binding
NLU04_RS09815	COG0783	Belongs to the Dps family
NLU04_RS09825	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS09830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NLU04_RS09835	COG1201	RNA secondary structure unwinding
NLU04_RS09840	COG2207	Transcriptional regulator
NLU04_RS09840	COG1917	Cupin 2, conserved barrel domain protein
NLU04_RS09875	COG1271	oxidase subunit
NLU04_RS09880	COG2197	response regulator
NLU04_RS09895	COG1672	PFAM Archaeal ATPase
NLU04_RS09895	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NLU04_RS09905	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NLU04_RS09935	COG0765	amino acid transport
NLU04_RS09940	COG0765	amino acid transport
NLU04_RS09945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NLU04_RS09950	COG1126	abc transporter atp-binding protein
NLU04_RS09955	COG0745	RESPONSE REGULATOR receiver
NLU04_RS09960	COG2205	protein histidine kinase activity
NLU04_RS09965	COG2358	TRAP transporter, solute receptor (TAXI family
NLU04_RS09970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NLU04_RS09985	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NLU04_RS09995	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NLU04_RS10000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLU04_RS10010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NLU04_RS10050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NLU04_RS10055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NLU04_RS10060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLU04_RS10095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLU04_RS10110	COG0514	ATP-dependent DNA helicase (RecQ)
NLU04_RS10130	COG2814	Major facilitator Superfamily
NLU04_RS10145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NLU04_RS10150	COG0574	Belongs to the PEP-utilizing enzyme family
NLU04_RS10150	COG3848	Pyruvate phosphate dikinase
NLU04_RS10155	COG1309	transcriptional regulator
NLU04_RS10170	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NLU04_RS10175	COG2186	Transcriptional regulator
NLU04_RS10180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NLU04_RS10205	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLU04_RS10210	COG4565	transcriptional regulatory protein
NLU04_RS10215	COG3290	protein histidine kinase activity
NLU04_RS10225	COG0372	Belongs to the citrate synthase family
NLU04_RS10230	COG0372	Belongs to the citrate synthase family
NLU04_RS10240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLU04_RS10245	COG0612	Peptidase, M16
NLU04_RS10260	COG1802	Transcriptional regulator
NLU04_RS10265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NLU04_RS10270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NLU04_RS10270	COG0045	succinate-CoA ligase (ADP-forming) activity
NLU04_RS10270	COG1042	CoA-binding domain protein
NLU04_RS10285	COG1435	thymidine kinase activity
NLU04_RS10320	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NLU04_RS10325	COG0483	inositol monophosphate 1-phosphatase activity
NLU04_RS10335	COG0745	RESPONSE REGULATOR receiver
NLU04_RS10340	COG2205	protein histidine kinase activity
NLU04_RS10365	COG0756	dUTP diphosphatase activity
NLU04_RS10400	COG0569	domain protein
NLU04_RS10405	COG0531	amino acid
NLU04_RS10410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLU04_RS10455	COG2815	serine threonine protein kinase
NLU04_RS10455	COG0515	serine threonine protein kinase
NLU04_RS10475	COG2366	antibiotic biosynthetic process
NLU04_RS10495	COG3629	intracellular signal transduction
NLU04_RS10495	COG3903	Transcriptional regulator
NLU04_RS10500	COG4585	Histidine kinase
NLU04_RS10520	COG0596	Alpha beta hydrolase
NLU04_RS10545	COG0464	growth
NLU04_RS10555	COG1674	ftsk spoiiie
NLU04_RS10625	COG2192	nodulation
NLU04_RS10655	COG0505	Belongs to the CarA family
NLU04_RS10660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NLU04_RS10665	COG1280	lysine exporter protein (LysE YggA)
NLU04_RS10670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NLU04_RS10680	COG3291	Pkd domain containing protein
NLU04_RS10685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NLU04_RS10705	COG3938	Belongs to the proline racemase family
NLU04_RS10710	COG1802	Transcriptional regulator
NLU04_RS10715	COG3835	regulator
NLU04_RS10735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS10740	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS10755	COG0586	Pfam SNARE associated Golgi protein
NLU04_RS10760	COG1349	DNA-binding transcription factor activity
NLU04_RS10765	COG1799	cell septum assembly
NLU04_RS10785	COG2040	homocysteine
NLU04_RS10795	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NLU04_RS10805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NLU04_RS10810	COG0531	amino acid
NLU04_RS10820	COG1024	Enoyl-CoA hydratase
NLU04_RS10850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NLU04_RS10850	COG2111	Na H antiporter
NLU04_RS10855	COG1006	Multisubunit Na H antiporter MnhC subunit
NLU04_RS10860	COG0651	ATP synthesis coupled electron transport
NLU04_RS10875	COG1320	monovalent cation:proton antiporter activity
NLU04_RS10890	COG0297	glycogen (starch) synthase activity
NLU04_RS10895	COG0489	protein tyrosine kinase activity
NLU04_RS10930	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NLU04_RS10935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NLU04_RS10940	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NLU04_RS10975	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS10985	COG3629	intracellular signal transduction
NLU04_RS10990	COG3629	intracellular signal transduction
NLU04_RS10990	COG3903	Transcriptional regulator
NLU04_RS11015	COG0515	serine threonine protein kinase
NLU04_RS11015	COG2815	serine threonine protein kinase
NLU04_RS11025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLU04_RS11030	COG2267	carboxylic ester hydrolase activity
NLU04_RS11040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NLU04_RS11050	COG0406	alpha-ribazole phosphatase activity
NLU04_RS11060	COG1653	transport
NLU04_RS11065	COG1175	transmembrane transport
NLU04_RS11070	COG0395	ABC-type sugar transport system, permease component
NLU04_RS11075	COG1940	carbohydrate kinase activity
NLU04_RS11080	COG4213	ABC transporter substrate-binding protein
NLU04_RS11090	COG4214	carbohydrate transport
NLU04_RS11095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NLU04_RS11100	COG0531	amino acid
NLU04_RS11105	COG3415	Transposase
NLU04_RS11105	COG2801	Transposase and inactivated derivatives
NLU04_RS11120	COG1316	TRANSCRIPTIONal
NLU04_RS11125	COG1024	Enoyl-CoA hydratase
NLU04_RS11125	COG1250	3-hydroxyacyl-CoA dehydrogenase
NLU04_RS11130	COG0183	Belongs to the thiolase family
NLU04_RS11150	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NLU04_RS11155	COG0446	pyridine nucleotide-disulphide oxidoreductase
NLU04_RS11165	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NLU04_RS11170	COG3253	May function as heme-dependent peroxidase
NLU04_RS11185	COG3220	belongs to the UPF0276 family
NLU04_RS11210	COG2376	Dihydroxyacetone kinase
NLU04_RS11220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NLU04_RS11260	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NLU04_RS11265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLU04_RS11305	COG2072	flavoprotein involved in K transport
NLU04_RS11335	COG0483	inositol monophosphate 1-phosphatase activity
NLU04_RS11370	COG1100	Small GTP-binding protein
NLU04_RS11395	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NLU04_RS11395	COG0515	serine threonine protein kinase
NLU04_RS11400	COG1063	alcohol dehydrogenase
NLU04_RS11405	COG0156	8-amino-7-oxononanoate synthase activity
NLU04_RS11420	COG0346	lactoylglutathione lyase activity
NLU04_RS11440	COG2723	6-phospho-beta-galactosidase activity
NLU04_RS11495	COG1175	transmembrane transport
NLU04_RS11515	COG1404	Belongs to the peptidase S8 family
NLU04_RS11520	COG2801	Transposase and inactivated derivatives
NLU04_RS11520	COG3415	Transposase
NLU04_RS11540	COG1132	(ABC) transporter
NLU04_RS11545	COG1132	(ABC) transporter
NLU04_RS11550	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NLU04_RS11560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NLU04_RS11565	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NLU04_RS11585	COG0529	Catalyzes the synthesis of activated sulfate
NLU04_RS11590	COG0175	sulfate reduction
NLU04_RS11615	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS11635	COG1250	3-hydroxyacyl-CoA dehydrogenase
NLU04_RS11640	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NLU04_RS11645	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NLU04_RS11650	COG0583	DNA-binding transcription factor activity
NLU04_RS11655	COG0183	Belongs to the thiolase family
NLU04_RS11660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NLU04_RS11710	COG1162	GTPase activity
NLU04_RS11730	COG1404	Belongs to the peptidase S8 family
NLU04_RS11740	COG0028	Belongs to the TPP enzyme family
NLU04_RS11760	COG1802	Transcriptional regulator
NLU04_RS11785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NLU04_RS11790	COG2252	PERMEase
NLU04_RS11795	COG3608	succinylglutamate desuccinylase aspartoacylase
NLU04_RS11795	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NLU04_RS11820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NLU04_RS11850	COG0435	Glutathione S-transferase
NLU04_RS11860	COG2197	response regulator
NLU04_RS11865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NLU04_RS11870	COG0318	PFAM AMP-dependent synthetase and ligase
NLU04_RS11890	COG3960	tartronate-semialdehyde synthase activity
NLU04_RS11905	COG3629	intracellular signal transduction
NLU04_RS11905	COG3903	Transcriptional regulator
NLU04_RS11915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NLU04_RS11925	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NLU04_RS11935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NLU04_RS11940	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NLU04_RS11955	COG0753	catalase activity
NLU04_RS11960	COG2084	Dehydrogenase
NLU04_RS11965	COG3622	Belongs to the hyi family
NLU04_RS11970	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NLU04_RS11980	COG0395	ABC-type sugar transport system, permease component
NLU04_RS11985	COG1175	transmembrane transport
NLU04_RS11995	COG2188	Transcriptional regulator
NLU04_RS12015	COG2351	hydroxyisourate hydrolase activity
NLU04_RS12025	COG2233	PERMEase
NLU04_RS12035	COG2233	PERMEase
NLU04_RS12080	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NLU04_RS12095	COG2197	response regulator
NLU04_RS12115	COG1414	Transcriptional regulator
NLU04_RS12120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NLU04_RS12125	COG4266	Belongs to the allantoicase family
NLU04_RS12130	COG0656	L-ascorbic acid biosynthetic process
NLU04_RS12135	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS12170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLU04_RS12170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLU04_RS12220	COG2271	Major facilitator Superfamily
NLU04_RS12230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NLU04_RS12235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NLU04_RS12245	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS12265	COG0529	Catalyzes the synthesis of activated sulfate
NLU04_RS12315	COG0673	inositol 2-dehydrogenase activity
NLU04_RS12320	COG2188	Transcriptional regulator
NLU04_RS12335	COG1129	ABC transporter
NLU04_RS12340	COG1940	carbohydrate kinase activity
NLU04_RS12350	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NLU04_RS12355	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NLU04_RS12370	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS12405	COG1126	abc transporter atp-binding protein
NLU04_RS12410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NLU04_RS12415	COG0765	amino acid transport
NLU04_RS12420	COG0765	amino acid transport
NLU04_RS12430	COG1376	ErfK ybiS ycfS ynhG family protein
NLU04_RS12445	COG0405	Gamma-glutamyltransferase
NLU04_RS12475	COG0667	Aldo Keto reductase
NLU04_RS12485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NLU04_RS12490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NLU04_RS12515	COG2838	Isocitrate dehydrogenase
NLU04_RS12525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NLU04_RS12535	COG0095	Lipoate-protein ligase
NLU04_RS12540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NLU04_RS12555	COG1024	Enoyl-CoA hydratase
NLU04_RS12560	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS12580	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NLU04_RS12595	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NLU04_RS12635	COG1024	Enoyl-CoA hydratase
NLU04_RS12640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NLU04_RS12670	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS12675	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS12680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLU04_RS12685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLU04_RS12695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NLU04_RS12705	COG1131	(ABC) transporter
NLU04_RS12710	COG1024	Enoyl-CoA hydratase
NLU04_RS12745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NLU04_RS12760	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NLU04_RS12775	COG1929	Belongs to the glycerate kinase type-1 family
NLU04_RS12795	COG0559	Belongs to the binding-protein-dependent transport system permease family
NLU04_RS12800	COG0559	Belongs to the binding-protein-dependent transport system permease family
NLU04_RS12830	COG0688	phosphatidylethanolamine metabolic process
NLU04_RS12835	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS12845	COG2301	Belongs to the HpcH HpaI aldolase family
NLU04_RS12850	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NLU04_RS12850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NLU04_RS12855	COG0604	alcohol dehydrogenase
NLU04_RS12875	COG1250	3-hydroxyacyl-CoA dehydrogenase
NLU04_RS12910	COG0667	Aldo Keto reductase
NLU04_RS12920	COG2362	D-Aminopeptidase
NLU04_RS12925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NLU04_RS12935	COG1619	proteins homologs of microcin C7 resistance protein MccF
NLU04_RS12950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NLU04_RS12965	COG2226	methyltransferase
NLU04_RS12985	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NLU04_RS13010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NLU04_RS13025	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NLU04_RS13025	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NLU04_RS13060	COG2154	pterin-4-alpha-carbinolamine dehydratase
NLU04_RS13070	COG4106	trans-aconitate 2-methyltransferase activity
NLU04_RS13080	COG0656	L-ascorbic acid biosynthetic process
NLU04_RS13090	COG0583	DNA-binding transcription factor activity
NLU04_RS13095	COG2801	Transposase and inactivated derivatives
NLU04_RS13095	COG3415	Transposase
NLU04_RS13115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NLU04_RS13120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLU04_RS13130	COG1129	ABC transporter
NLU04_RS13135	COG1172	Belongs to the binding-protein-dependent transport system permease family
NLU04_RS13145	COG0673	inositol 2-dehydrogenase activity
NLU04_RS13225	COG1609	Transcriptional regulator
NLU04_RS13230	COG1129	ABC transporter
NLU04_RS13240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLU04_RS13245	COG1869	D-ribose catabolic process
NLU04_RS13270	COG5002	protein histidine kinase activity
NLU04_RS13275	COG0745	RESPONSE REGULATOR receiver
NLU04_RS13305	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS13315	COG0517	IMP dehydrogenase activity
NLU04_RS13315	COG4175	Glycine betaine
NLU04_RS13320	COG4176	ABC-type proline glycine betaine transport system permease component
NLU04_RS13330	COG2124	cytochrome p450
NLU04_RS13335	COG0569	domain protein
NLU04_RS13335	COG2985	domain, Protein
NLU04_RS13350	COG1070	Carbohydrate kinase
NLU04_RS13360	COG1940	carbohydrate kinase activity
NLU04_RS13385	COG1846	Transcriptional regulator
NLU04_RS13410	COG2124	cytochrome p450
NLU04_RS13415	COG1486	melibiose metabolic process
NLU04_RS13455	COG3012	SEC-C Motif Domain Protein
NLU04_RS13510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NLU04_RS13535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NLU04_RS13570	COG2770	Histidine kinase
NLU04_RS13570	COG2208	phosphoserine phosphatase activity
NLU04_RS13590	COG1793	dna ligase
NLU04_RS13670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NLU04_RS13675	COG0488	(ABC) transporter
NLU04_RS13690	COG1515	deoxyribonuclease V activity
NLU04_RS13700	COG3268	Saccharopine dehydrogenase
NLU04_RS13705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NLU04_RS13710	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS13715	COG0183	Belongs to the thiolase family
NLU04_RS13720	COG1024	Enoyl-CoA hydratase
NLU04_RS13720	COG1250	3-hydroxyacyl-CoA dehydrogenase
NLU04_RS13725	COG0789	Transcriptional regulator
NLU04_RS13750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NLU04_RS13770	COG0488	(ABC) transporter
NLU04_RS13775	COG2183	response to ionizing radiation
NLU04_RS13785	COG4977	sequence-specific DNA binding
NLU04_RS13795	COG1024	Enoyl-CoA hydratase
NLU04_RS13810	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NLU04_RS13815	COG2226	methyltransferase
NLU04_RS13845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NLU04_RS13860	COG1134	teichoic acid transport
NLU04_RS13860	COG1388	LysM domain
NLU04_RS13865	COG1562	ergosterol biosynthetic process
NLU04_RS13875	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NLU04_RS13885	COG1657	PFAM Prenyltransferase squalene oxidase
NLU04_RS13915	COG2365	Tyrosine phosphatase family
NLU04_RS13925	COG2755	lipolytic protein G-D-S-L family
NLU04_RS13935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NLU04_RS13975	COG3467	pyridoxamine 5'-phosphate
NLU04_RS14015	COG1609	Transcriptional regulator
NLU04_RS14020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NLU04_RS14030	COG1116	anion transmembrane transporter activity
NLU04_RS14060	COG3958	Transketolase
NLU04_RS14065	COG3959	Transketolase, thiamine diphosphate binding domain
NLU04_RS14090	COG0456	acetyltransferase
NLU04_RS14090	COG1846	Transcriptional regulator
NLU04_RS14125	COG1215	transferase activity, transferring glycosyl groups
NLU04_RS14150	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS14165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLU04_RS14180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLU04_RS14200	COG0318	PFAM AMP-dependent synthetase and ligase
NLU04_RS14220	COG3511	phospholipase C
NLU04_RS14230	COG2197	response regulator
NLU04_RS14235	COG3851	Histidine kinase
NLU04_RS14255	COG0247	lactate metabolic process
NLU04_RS14260	COG1139	Iron-sulfur cluster binding protein
NLU04_RS14265	COG1556	Lactate utilization protein
NLU04_RS14285	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NLU04_RS14285	COG1672	PFAM Archaeal ATPase
NLU04_RS14295	COG0318	PFAM AMP-dependent synthetase and ligase
NLU04_RS14305	COG0156	8-amino-7-oxononanoate synthase activity
NLU04_RS14320	COG3321	synthase
NLU04_RS14320	COG0604	alcohol dehydrogenase
NLU04_RS14330	COG3321	synthase
NLU04_RS14330	COG0604	alcohol dehydrogenase
NLU04_RS14335	COG1250	3-hydroxyacyl-CoA dehydrogenase
NLU04_RS14360	COG3903	Transcriptional regulator
NLU04_RS14360	COG3629	intracellular signal transduction
NLU04_RS14385	COG1396	sequence-specific DNA binding
NLU04_RS14385	COG3800	Transcriptional regulator
NLU04_RS14390	COG2079	MmgE PrpD family protein
NLU04_RS14405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLU04_RS14425	COG1316	TRANSCRIPTIONal
NLU04_RS14435	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NLU04_RS14440	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NLU04_RS14445	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NLU04_RS14470	COG0714	Associated with various cellular activities
NLU04_RS14495	COG0831	urea catabolic process
NLU04_RS14510	COG0830	nickel cation binding
NLU04_RS14515	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NLU04_RS14520	COG0829	nickel cation binding
NLU04_RS14570	COG0446	pyridine nucleotide-disulphide oxidoreductase
NLU04_RS14570	COG1902	pentaerythritol trinitrate reductase activity
NLU04_RS14585	COG2409	Drug exporters of the RND superfamily
NLU04_RS14590	COG1846	Transcriptional regulator
NLU04_RS14645	COG1233	COG1233 Phytoene dehydrogenase and related
NLU04_RS14650	COG2130	NADP-dependent
NLU04_RS14655	COG2124	cytochrome p450
NLU04_RS14670	COG2080	2 iron, 2 sulfur cluster binding
NLU04_RS14675	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NLU04_RS14680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NLU04_RS14695	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NLU04_RS14705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NLU04_RS14720	COG0019	diaminopimelate decarboxylase activity
NLU04_RS14730	COG2837	iron assimilation
NLU04_RS14735	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NLU04_RS14775	COG0596	Alpha beta hydrolase
NLU04_RS14785	COG0395	ABC-type sugar transport system, permease component
NLU04_RS14790	COG1175	transmembrane transport
NLU04_RS14800	COG1940	carbohydrate kinase activity
NLU04_RS14810	COG1652	LysM domain
NLU04_RS14845	COG0784	Response regulator, receiver
NLU04_RS14850	COG4251	negative regulation of phosphorylation
NLU04_RS14855	COG2201	protein-glutamate methylesterase activity
NLU04_RS14860	COG1191	sigma factor activity
NLU04_RS14905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NLU04_RS14925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLU04_RS14930	COG3275	phosphorelay sensor kinase activity
NLU04_RS15010	COG0583	DNA-binding transcription factor activity
NLU04_RS15020	COG1053	succinate dehydrogenase
NLU04_RS15025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NLU04_RS15040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NLU04_RS15045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NLU04_RS15055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NLU04_RS15060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NLU04_RS15065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NLU04_RS15095	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NLU04_RS15105	COG2197	response regulator
NLU04_RS15110	COG2423	ornithine cyclodeaminase activity
NLU04_RS15115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NLU04_RS15130	COG3360	Dodecin
NLU04_RS15150	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
NLU04_RS15155	COG0121	glutamine amidotransferase
NLU04_RS15160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NLU04_RS15165	COG3572	ergothioneine biosynthetic process
NLU04_RS15190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NLU04_RS15195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NLU04_RS15200	COG1834	amidinotransferase
NLU04_RS15215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLU04_RS15230	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NLU04_RS15255	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS15285	COG0243	molybdopterin cofactor binding
NLU04_RS15310	COG0747	negative chemotaxis
NLU04_RS15315	COG0601	transmembrane transport
NLU04_RS15320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLU04_RS15325	COG0444	Belongs to the ABC transporter superfamily
NLU04_RS15330	COG4608	Belongs to the ABC transporter superfamily
NLU04_RS15335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLU04_RS15340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NLU04_RS15355	COG0431	NADPH-dependent FMN reductase
NLU04_RS15405	COG1120	ATPase activity
NLU04_RS15415	COG0477	Major facilitator Superfamily
NLU04_RS15420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NLU04_RS15430	COG0254	rRNA binding
NLU04_RS15435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NLU04_RS15440	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NLU04_RS15445	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLU04_RS15465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS15470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS15475	COG1120	ATPase activity
NLU04_RS15505	COG1132	(ABC) transporter
NLU04_RS15510	COG1132	(ABC) transporter
NLU04_RS15555	COG0438	transferase activity, transferring glycosyl groups
NLU04_RS15580	COG0438	transferase activity, transferring glycosyl groups
NLU04_RS15580	COG0297	glycogen (starch) synthase activity
NLU04_RS15620	COG1174	glycine betaine transport
NLU04_RS15625	COG1174	glycine betaine transport
NLU04_RS15645	COG1125	glycine betaine transport
NLU04_RS15645	COG0517	IMP dehydrogenase activity
NLU04_RS15655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NLU04_RS15675	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS15680	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS15695	COG0601	transmembrane transport
NLU04_RS15700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLU04_RS15705	COG0444	Belongs to the ABC transporter superfamily
NLU04_RS15770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NLU04_RS15770	COG1796	DNA polymerase
NLU04_RS15810	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NLU04_RS15855	COG1278	Cold shock
NLU04_RS15870	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NLU04_RS15890	COG4044	May play a role in the intracellular transport of hydrophobic ligands
NLU04_RS15930	COG5297	Belongs to the glycosyl hydrolase family 6
NLU04_RS15940	COG3300	MHYT domain
NLU04_RS15940	COG5001	Diguanylate cyclase
NLU04_RS15955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NLU04_RS15955	COG2146	nitrite reductase [NAD(P)H] activity
NLU04_RS15960	COG2146	nitrite reductase [NAD(P)H] activity
NLU04_RS15960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NLU04_RS15965	COG0243	molybdopterin cofactor binding
NLU04_RS15970	COG2223	nitrite transmembrane transporter activity
NLU04_RS16025	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NLU04_RS16055	COG0745	RESPONSE REGULATOR receiver
NLU04_RS16070	COG1120	ATPase activity
NLU04_RS16125	COG4585	Histidine kinase
NLU04_RS16130	COG2197	response regulator
NLU04_RS16140	COG0577	efflux transmembrane transporter activity
NLU04_RS16140	COG1136	(ABC) transporter
NLU04_RS16155	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS16175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NLU04_RS16180	COG3239	Fatty acid desaturase
NLU04_RS16200	COG2267	carboxylic ester hydrolase activity
NLU04_RS16215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NLU04_RS16220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NLU04_RS16225	COG0640	Transcriptional regulator
NLU04_RS16240	COG2018	Roadblock/LC7 domain
NLU04_RS16265	COG1024	Enoyl-CoA hydratase
NLU04_RS16305	COG1595	DNA-templated transcription, initiation
NLU04_RS16320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NLU04_RS16325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NLU04_RS16335	COG2340	Cysteine-rich secretory protein family
NLU04_RS16365	COG0488	(ABC) transporter
NLU04_RS16380	COG0009	L-threonylcarbamoyladenylate synthase
NLU04_RS16415	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
NLU04_RS16435	COG0142	geranyltranstransferase activity
NLU04_RS16440	COG5297	Belongs to the glycosyl hydrolase family 6
NLU04_RS16440	COG3250	beta-galactosidase activity
NLU04_RS16450	COG0789	Transcriptional regulator
NLU04_RS16455	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NLU04_RS16470	COG1891	lyase activity
NLU04_RS16480	COG2890	protein-(glutamine-N5) methyltransferase activity
NLU04_RS16520	COG1175	transmembrane transport
NLU04_RS16525	COG0395	ABC-type sugar transport system, permease component
NLU04_RS16530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLU04_RS16535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NLU04_RS16545	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NLU04_RS16570	COG2367	Beta-lactamase
NLU04_RS16620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS16625	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NLU04_RS16635	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NLU04_RS16685	COG1505	serine-type exopeptidase activity
NLU04_RS16700	COG0367	asparagine synthase
NLU04_RS16705	COG0477	Major facilitator Superfamily
NLU04_RS16710	COG2050	protein possibly involved in aromatic compounds catabolism
NLU04_RS16720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NLU04_RS16725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NLU04_RS16735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLU04_RS16740	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS16815	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NLU04_RS16820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NLU04_RS16830	COG1846	Transcriptional regulator
NLU04_RS16835	COG1764	response to oxidative stress
NLU04_RS16845	COG0789	Transcriptional regulator
NLU04_RS16870	COG0277	FAD linked oxidase domain protein
NLU04_RS16880	COG1902	pentaerythritol trinitrate reductase activity
NLU04_RS16885	COG0640	Transcriptional regulator
NLU04_RS16890	COG1064	alcohol dehydrogenase
NLU04_RS16910	COG0702	epimerase
NLU04_RS16940	COG0642	Histidine kinase
NLU04_RS16960	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NLU04_RS16965	COG0366	Alpha amylase catalytic
NLU04_RS16970	COG0395	ABC-type sugar transport system, permease component
NLU04_RS16975	COG1175	transmembrane transport
NLU04_RS17025	COG1349	DNA-binding transcription factor activity
NLU04_RS17030	COG1105	Belongs to the carbohydrate kinase PfkB family
NLU04_RS17105	COG0254	rRNA binding
NLU04_RS17165	COG1024	Enoyl-CoA hydratase
NLU04_RS17190	COG0765	amino acid transport
NLU04_RS17200	COG0318	PFAM AMP-dependent synthetase and ligase
NLU04_RS17205	COG2366	antibiotic biosynthetic process
NLU04_RS17215	COG2070	2-Nitropropane dioxygenase
NLU04_RS17230	COG0515	serine threonine protein kinase
NLU04_RS17240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NLU04_RS17245	COG0346	lactoylglutathione lyase activity
NLU04_RS17260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLU04_RS17270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLU04_RS17270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NLU04_RS17270	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NLU04_RS17270	COG3321	synthase
NLU04_RS17270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLU04_RS17270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NLU04_RS17270	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NLU04_RS17270	COG3321	synthase
NLU04_RS17275	COG0300	oxidoreductase activity
NLU04_RS17275	COG3321	synthase
NLU04_RS17275	COG0318	PFAM AMP-dependent synthetase and ligase
NLU04_RS17275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NLU04_RS17275	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS17280	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS17285	COG2813	Specifically methylates the guanine in position
NLU04_RS17300	COG2356	endonuclease I
NLU04_RS17305	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NLU04_RS17305	COG2066	Belongs to the glutaminase family
NLU04_RS17320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NLU04_RS17325	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NLU04_RS17340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NLU04_RS17345	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NLU04_RS17350	COG2080	2 iron, 2 sulfur cluster binding
NLU04_RS17410	COG2365	Tyrosine phosphatase family
NLU04_RS17435	COG1120	ATPase activity
NLU04_RS17440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NLU04_RS17450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NLU04_RS17460	COG0477	Major facilitator Superfamily
NLU04_RS17465	COG2382	esterase
NLU04_RS17470	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS17475	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS17480	COG1169	isochorismate synthase
NLU04_RS17485	COG1021	2,3-dihydroxybenzoate-AMP ligase
NLU04_RS17490	COG1535	isochorismatase
NLU04_RS17490	COG3433	isochorismatase activity
NLU04_RS17495	COG1535	isochorismatase
NLU04_RS17495	COG3433	isochorismatase activity
NLU04_RS17515	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NLU04_RS17550	COG3845	ABC transporter
NLU04_RS17575	COG1470	cell adhesion involved in biofilm formation
NLU04_RS17595	COG1132	(ABC) transporter
NLU04_RS17610	COG1063	alcohol dehydrogenase
NLU04_RS17615	COG0395	ABC-type sugar transport system, permease component
NLU04_RS17630	COG1349	DNA-binding transcription factor activity
NLU04_RS17660	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NLU04_RS17685	COG2382	esterase
NLU04_RS17690	COG1132	(ABC) transporter
NLU04_RS17700	COG1132	(ABC) transporter
NLU04_RS17710	COG1120	ATPase activity
NLU04_RS17715	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS17720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS17725	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NLU04_RS17740	COG4104	PAAR repeat-containing protein
NLU04_RS17740	COG3209	COG3209 Rhs family protein
NLU04_RS17780	COG0640	Transcriptional regulator
NLU04_RS17815	COG1132	(ABC) transporter
NLU04_RS17820	COG1132	(ABC) transporter
NLU04_RS17825	COG1181	Belongs to the D-alanine--D-alanine ligase family
NLU04_RS17840	COG1181	Belongs to the D-alanine--D-alanine ligase family
NLU04_RS17860	COG0504	CTP synthase activity
NLU04_RS17865	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NLU04_RS17870	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NLU04_RS17875	COG2197	response regulator
NLU04_RS17880	COG0640	Transcriptional regulator
NLU04_RS17885	COG0243	molybdopterin cofactor binding
NLU04_RS17910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NLU04_RS17915	COG0573	inorganic phosphate transmembrane transporter activity
NLU04_RS17920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NLU04_RS17925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NLU04_RS17930	COG0798	PFAM Bile acid sodium symporter
NLU04_RS17940	COG2226	methyltransferase
NLU04_RS17950	COG0583	DNA-binding transcription factor activity
NLU04_RS17955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLU04_RS17965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NLU04_RS17975	COG1116	anion transmembrane transporter activity
NLU04_RS17995	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NLU04_RS18020	COG0640	Transcriptional regulator
NLU04_RS18055	COG1191	sigma factor activity
NLU04_RS18090	COG0297	glycogen (starch) synthase activity
NLU04_RS18110	COG0531	amino acid
NLU04_RS18135	COG1982	Orn Lys Arg decarboxylase major
NLU04_RS18170	COG2376	Dihydroxyacetone kinase
NLU04_RS18175	COG1461	Dihydroxyacetone kinase
NLU04_RS18190	COG0488	(ABC) transporter
NLU04_RS18220	COG1191	sigma factor activity
NLU04_RS18230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NLU04_RS18235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NLU04_RS18250	COG1120	ATPase activity
NLU04_RS18255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS18280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NLU04_RS18325	COG1063	alcohol dehydrogenase
NLU04_RS18330	COG1959	2 iron, 2 sulfur cluster binding
NLU04_RS18330	COG1295	ribonuclease BN
NLU04_RS18360	COG2837	iron assimilation
NLU04_RS18365	COG1120	ATPase activity
NLU04_RS18370	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS18375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS18395	COG0617	tRNA 3'-terminal CCA addition
NLU04_RS18400	COG2207	Transcriptional regulator
NLU04_RS18415	COG0366	Alpha amylase catalytic
NLU04_RS18415	COG1874	Beta-galactosidase
NLU04_RS18430	COG1609	Transcriptional regulator
NLU04_RS18435	COG1172	Belongs to the binding-protein-dependent transport system permease family
NLU04_RS18445	COG1129	ABC transporter
NLU04_RS18450	COG1879	ABC-type sugar transport system periplasmic component
NLU04_RS18455	COG3250	beta-galactosidase activity
NLU04_RS18500	COG0328	RNA-DNA hybrid ribonuclease activity
NLU04_RS18505	COG1132	(ABC) transporter
NLU04_RS18515	COG2264	protein methyltransferase activity
NLU04_RS18565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NLU04_RS18620	COG2045	Belongs to the ComB family
NLU04_RS18640	COG0464	growth
NLU04_RS18650	COG1349	DNA-binding transcription factor activity
NLU04_RS18665	COG0702	epimerase
NLU04_RS18705	COG1940	carbohydrate kinase activity
NLU04_RS18710	COG2223	nitrite transmembrane transporter activity
NLU04_RS18750	COG0445	tRNA wobble uridine modification
NLU04_RS18765	COG1660	Displays ATPase and GTPase activities
NLU04_RS18770	COG1940	carbohydrate kinase activity
NLU04_RS18795	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NLU04_RS18840	COG0584	glycerophosphoryl diester phosphodiesterase
NLU04_RS18845	COG0456	acetyltransferase
NLU04_RS18860	COG0671	phosphoesterase, PA-phosphatase related
NLU04_RS18910	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NLU04_RS18915	COG2971	BadF BadG BcrA BcrD
NLU04_RS18925	COG2706	6-phosphogluconolactonase activity
NLU04_RS18935	COG2801	Transposase and inactivated derivatives
NLU04_RS18935	COG3415	Transposase
NLU04_RS18950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NLU04_RS18955	COG2815	serine threonine protein kinase
NLU04_RS18955	COG0515	serine threonine protein kinase
NLU04_RS18960	COG0667	Aldo Keto reductase
NLU04_RS18990	COG1253	flavin adenine dinucleotide binding
NLU04_RS19030	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NLU04_RS19035	COG0531	amino acid
NLU04_RS19040	COG2186	Transcriptional regulator
NLU04_RS19045	COG0174	glutamine synthetase
NLU04_RS19050	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS19060	COG1609	Transcriptional regulator
NLU04_RS19065	COG1653	transport
NLU04_RS19070	COG1175	transmembrane transport
NLU04_RS19080	COG1472	Belongs to the glycosyl hydrolase 3 family
NLU04_RS19110	COG4981	capsule polysaccharide biosynthetic process
NLU04_RS19130	COG2835	tetraacyldisaccharide 4'-kinase activity
NLU04_RS19155	COG0243	molybdopterin cofactor binding
NLU04_RS19180	COG1357	PFAM Pentapeptide repeats (8 copies)
NLU04_RS19185	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS19190	COG1982	Orn Lys Arg decarboxylase major
NLU04_RS19255	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS19260	COG2124	cytochrome p450
NLU04_RS19275	COG1335	isochorismatase
NLU04_RS19330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NLU04_RS19340	COG0542	response to heat
NLU04_RS19355	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS19360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS19370	COG4592	Periplasmic binding protein
NLU04_RS19405	COG0385	Bile acid
NLU04_RS19435	COG0583	DNA-binding transcription factor activity
NLU04_RS19455	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NLU04_RS19475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NLU04_RS19480	COG1116	anion transmembrane transporter activity
NLU04_RS19490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLU04_RS19495	COG2072	flavoprotein involved in K transport
NLU04_RS19510	COG1132	(ABC) transporter
NLU04_RS19520	COG0277	FAD linked oxidase domain protein
NLU04_RS19530	COG1132	(ABC) transporter
NLU04_RS19535	COG1132	(ABC) transporter
NLU04_RS19560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NLU04_RS19560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NLU04_RS19575	COG1252	NADH dehydrogenase
NLU04_RS19580	COG1793	dna ligase
NLU04_RS19595	COG1946	Acyl-CoA thioesterase
NLU04_RS19610	COG0386	Belongs to the glutathione peroxidase family
NLU04_RS19615	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS19625	COG0242	peptide deformylase activity
NLU04_RS19635	COG3442	glutamine amidotransferase
NLU04_RS19640	COG0205	6-phosphofructokinase activity
NLU04_RS19670	COG0829	nickel cation binding
NLU04_RS19675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NLU04_RS19685	COG0804	urea catabolic process
NLU04_RS19690	COG0832	Belongs to the urease beta subunit family
NLU04_RS19695	COG0831	urea catabolic process
NLU04_RS19740	COG0156	8-amino-7-oxononanoate synthase activity
NLU04_RS19745	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NLU04_RS19750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NLU04_RS19755	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NLU04_RS19760	COG2226	methyltransferase
NLU04_RS19785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NLU04_RS19790	COG3663	DNA glycosylase
NLU04_RS19800	COG1940	carbohydrate kinase activity
NLU04_RS19805	COG2188	Transcriptional regulator
NLU04_RS19810	COG1595	DNA-templated transcription, initiation
NLU04_RS19840	COG0626	cystathionine gamma-synthase activity
NLU04_RS19860	COG1522	sequence-specific DNA binding
NLU04_RS19865	COG0419	ATPase involved in DNA repair
NLU04_RS19870	COG0420	3'-5' exonuclease activity
NLU04_RS19875	COG1739	Uncharacterized protein family UPF0029
NLU04_RS19880	COG1832	CoA-binding protein
NLU04_RS19920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NLU04_RS19935	COG1968	undecaprenyl-diphosphatase activity
NLU04_RS19945	COG2226	methyltransferase
NLU04_RS19950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NLU04_RS20000	COG2318	DinB family
NLU04_RS20015	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NLU04_RS20100	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NLU04_RS20165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NLU04_RS20175	COG1132	(ABC) transporter
NLU04_RS20180	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NLU04_RS20185	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NLU04_RS20530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NLU04_RS20580	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NLU04_RS20580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NLU04_RS20600	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NLU04_RS20610	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS20615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NLU04_RS20625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NLU04_RS20640	COG2409	Drug exporters of the RND superfamily
NLU04_RS20645	COG2205	protein histidine kinase activity
NLU04_RS20650	COG0745	RESPONSE REGULATOR receiver
NLU04_RS20660	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLU04_RS20665	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NLU04_RS20680	COG1937	Protein conserved in bacteria
NLU04_RS20690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NLU04_RS20690	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NLU04_RS20695	COG0785	Cytochrome C biogenesis protein
NLU04_RS20700	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NLU04_RS20705	COG0730	response to heat
NLU04_RS20810	COG0714	Associated with various cellular activities
NLU04_RS20955	COG0659	secondary active sulfate transmembrane transporter activity
NLU04_RS20960	COG0789	Transcriptional regulator
NLU04_RS20965	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLU04_RS20985	COG1309	transcriptional regulator
NLU04_RS20990	COG3973	AAA domain
NLU04_RS20995	COG1968	undecaprenyl-diphosphatase activity
NLU04_RS21005	COG2271	Major facilitator Superfamily
NLU04_RS21010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NLU04_RS21015	COG0659	secondary active sulfate transmembrane transporter activity
NLU04_RS21040	COG3594	Acyltransferase
NLU04_RS21045	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NLU04_RS21055	COG0205	6-phosphofructokinase activity
NLU04_RS21065	COG0438	transferase activity, transferring glycosyl groups
NLU04_RS21075	COG1686	Belongs to the peptidase S11 family
NLU04_RS21115	COG2188	Transcriptional regulator
NLU04_RS21140	COG0583	DNA-binding transcription factor activity
NLU04_RS21170	COG0697	spore germination
NLU04_RS21210	COG1695	Transcriptional regulator
NLU04_RS21255	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NLU04_RS21255	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NLU04_RS21265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLU04_RS21285	COG1716	ATPase activity
NLU04_RS21305	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NLU04_RS21335	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NLU04_RS21345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NLU04_RS21360	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NLU04_RS21390	COG2018	Roadblock/LC7 domain
NLU04_RS21460	COG2364	Membrane
NLU04_RS21470	COG2270	Major facilitator Superfamily
NLU04_RS21480	COG3030	protein affecting phage T7 exclusion by the F plasmid
NLU04_RS21485	COG1216	Glycosyl transferase, family 2
NLU04_RS21505	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS21550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NLU04_RS21555	COG0140	phosphoribosyl-ATP diphosphatase activity
NLU04_RS21560	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NLU04_RS21570	COG3201	nicotinamide mononucleotide transporter
NLU04_RS21595	COG0738	Major facilitator superfamily
NLU04_RS21600	COG2233	PERMEase
NLU04_RS21615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NLU04_RS21625	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS21640	COG2390	Transcriptional regulator
NLU04_RS21645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NLU04_RS21655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NLU04_RS21670	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NLU04_RS21680	COG1758	RNA polymerase activity
NLU04_RS21695	COG0284	orotidine-5'-phosphate decarboxylase activity
NLU04_RS21700	COG0167	dihydroorotate dehydrogenase activity
NLU04_RS21705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NLU04_RS21710	COG0505	Belongs to the CarA family
NLU04_RS21720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NLU04_RS21725	COG0540	Belongs to the ATCase OTCase family
NLU04_RS21730	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NLU04_RS21740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NLU04_RS21745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NLU04_RS21750	COG0006	proline dipeptidase activity
NLU04_RS21760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NLU04_RS21765	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NLU04_RS21770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NLU04_RS21775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NLU04_RS21785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NLU04_RS21790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NLU04_RS21810	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NLU04_RS21830	COG0124	histidyl-tRNA synthetase
NLU04_RS21845	COG1196	nuclear chromosome segregation
NLU04_RS21850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLU04_RS21855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NLU04_RS21860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NLU04_RS21865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NLU04_RS21875	COG2255	four-way junction helicase activity
NLU04_RS21880	COG0632	four-way junction helicase activity
NLU04_RS21890	COG0217	transcriptional regulatory protein
NLU04_RS21895	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NLU04_RS21900	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NLU04_RS21910	COG0438	transferase activity, transferring glycosyl groups
NLU04_RS21915	COG1560	Kdo2-lipid A biosynthetic process
NLU04_RS21920	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NLU04_RS21945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NLU04_RS21960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NLU04_RS22020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NLU04_RS22075	COG1648	precorrin-2 dehydrogenase activity
NLU04_RS22075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NLU04_RS22080	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NLU04_RS22095	COG1464	Belongs to the NlpA lipoprotein family
NLU04_RS22100	COG2011	ABC-type metal ion transport system permease component
NLU04_RS22140	COG0477	Major facilitator Superfamily
NLU04_RS22150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NLU04_RS22155	COG3973	AAA domain
NLU04_RS22165	COG0165	Argininosuccinate lyase
NLU04_RS22170	COG0137	argininosuccinate synthase activity
NLU04_RS22180	COG1438	arginine binding
NLU04_RS22185	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NLU04_RS22190	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NLU04_RS22195	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NLU04_RS22200	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NLU04_RS22250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NLU04_RS22265	COG0697	spore germination
NLU04_RS22275	COG1649	PFAM Uncharacterised BCR, COG1649
NLU04_RS22295	COG0072	phenylalanine-tRNA ligase activity
NLU04_RS22295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLU04_RS22300	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NLU04_RS22305	COG5002	protein histidine kinase activity
NLU04_RS22310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLU04_RS22315	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NLU04_RS22320	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NLU04_RS22325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NLU04_RS22385	COG0517	IMP dehydrogenase activity
NLU04_RS22385	COG4175	Glycine betaine
NLU04_RS22390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLU04_RS22415	COG1595	DNA-templated transcription, initiation
NLU04_RS22435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NLU04_RS22440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NLU04_RS22485	COG0805	protein transport
NLU04_RS22490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NLU04_RS22510	COG2378	regulation of single-species biofilm formation
NLU04_RS22520	COG0545	Peptidyl-prolyl cis-trans isomerase
NLU04_RS22525	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NLU04_RS22535	COG1609	Transcriptional regulator
NLU04_RS22540	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NLU04_RS22545	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NLU04_RS22560	COG4122	O-methyltransferase activity
NLU04_RS22565	COG1222	aaa ATPase
NLU04_RS22585	COG0517	IMP dehydrogenase activity
NLU04_RS22585	COG1994	Peptidase M50
NLU04_RS22595	COG2197	response regulator
NLU04_RS22600	COG4166	transmembrane transport
NLU04_RS22610	COG0646	methionine synthase
NLU04_RS22610	COG1410	methionine synthase
NLU04_RS22615	COG1414	Transcriptional regulator
NLU04_RS22620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NLU04_RS22625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NLU04_RS22630	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NLU04_RS22635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLU04_RS22645	COG0215	cysteine-tRNA ligase activity
NLU04_RS22665	COG0598	Magnesium transport protein CorA
NLU04_RS22675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLU04_RS22680	COG0667	Aldo Keto reductase
NLU04_RS22710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NLU04_RS22720	COG0564	pseudouridine synthase activity
NLU04_RS22735	COG2186	Transcriptional regulator
NLU04_RS22740	COG3265	gluconokinase activity
NLU04_RS22765	COG3573	Dehydrogenase
NLU04_RS22770	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NLU04_RS22775	COG2149	membrane
NLU04_RS22795	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS22800	COG2234	aminopeptidase activity
NLU04_RS22800	COG4935	Belongs to the peptidase S8 family
NLU04_RS22810	COG0318	PFAM AMP-dependent synthetase and ligase
NLU04_RS22815	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS22820	COG3876	Protein conserved in bacteria
NLU04_RS22840	COG0789	Transcriptional regulator
NLU04_RS22860	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS22870	COG2326	polyphosphate kinase activity
NLU04_RS22890	COG2851	Citrate transporter
NLU04_RS22895	COG0243	molybdopterin cofactor binding
NLU04_RS22900	COG1309	transcriptional regulator
NLU04_RS22905	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NLU04_RS22910	COG2188	Transcriptional regulator
NLU04_RS22920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NLU04_RS22930	COG2755	lipolytic protein G-D-S-L family
NLU04_RS22940	COG1725	Transcriptional regulator
NLU04_RS22955	COG0346	lactoylglutathione lyase activity
NLU04_RS22975	COG4565	transcriptional regulatory protein
NLU04_RS22995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLU04_RS23000	COG0587	DNA-directed DNA polymerase activity
NLU04_RS23030	COG0641	radical SAM
NLU04_RS23060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLU04_RS23070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NLU04_RS23090	COG0765	amino acid transport
NLU04_RS23095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NLU04_RS23105	COG1799	cell septum assembly
NLU04_RS23110	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS23115	COG0477	Major facilitator Superfamily
NLU04_RS23120	COG0671	phosphoesterase, PA-phosphatase related
NLU04_RS23145	COG0438	transferase activity, transferring glycosyl groups
NLU04_RS23160	COG1160	GTP binding
NLU04_RS23170	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NLU04_RS23190	COG3541	Predicted nucleotidyltransferase
NLU04_RS23195	COG3541	Predicted nucleotidyltransferase
NLU04_RS23205	COG0494	nUDIX hydrolase
NLU04_RS23220	COG1187	pseudouridine synthase activity
NLU04_RS23225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NLU04_RS23230	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NLU04_RS23245	COG0686	Belongs to the AlaDH PNT family
NLU04_RS23255	COG0494	nUDIX hydrolase
NLU04_RS23260	COG0504	CTP synthase activity
NLU04_RS23265	COG3387	PFAM Glycoside hydrolase 15-related
NLU04_RS23285	COG3119	arylsulfatase activity
NLU04_RS23290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NLU04_RS23300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLU04_RS23305	COG0601	transmembrane transport
NLU04_RS23310	COG4166	transmembrane transport
NLU04_RS23335	COG0497	DNA recombination
NLU04_RS23340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NLU04_RS23360	COG1120	ATPase activity
NLU04_RS23365	COG0647	UMP catabolic process
NLU04_RS23400	COG2094	Belongs to the DNA glycosylase MPG family
NLU04_RS23410	COG1881	PFAM PEBP family protein
NLU04_RS23435	COG1119	ATPase activity
NLU04_RS23445	COG2197	response regulator
NLU04_RS23460	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NLU04_RS23470	COG1716	ATPase activity
NLU04_RS23470	COG1131	(ABC) transporter
NLU04_RS23470	COG0842	Transport permease protein
NLU04_RS23475	COG3830	Belongs to the UPF0237 family
NLU04_RS23475	COG0560	Phosphoserine phosphatase
NLU04_RS23500	COG2186	Transcriptional regulator
NLU04_RS23510	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NLU04_RS23515	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS23530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NLU04_RS23535	COG2261	transglycosylase associated protein
NLU04_RS23550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NLU04_RS23555	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLU04_RS23585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NLU04_RS23600	COG3387	PFAM Glycoside hydrolase 15-related
NLU04_RS23640	COG1024	Enoyl-CoA hydratase
NLU04_RS23650	COG0488	(ABC) transporter
NLU04_RS23675	COG0235	Class ii aldolase
NLU04_RS23690	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NLU04_RS23695	COG1492	cobalamin metabolic process
NLU04_RS23710	COG1797	cobyrinic acid a,c-diamide synthase activity
NLU04_RS23735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NLU04_RS23765	COG1902	pentaerythritol trinitrate reductase activity
NLU04_RS23770	COG1846	Transcriptional regulator
NLU04_RS23800	COG0768	penicillin binding
NLU04_RS23805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLU04_RS23815	COG0431	NADPH-dependent FMN reductase
NLU04_RS23830	COG0583	DNA-binding transcription factor activity
NLU04_RS23865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLU04_RS23870	COG2171	N-acyltransferase activity
NLU04_RS23885	COG3226	Transcriptional regulator
NLU04_RS23905	COG2151	metal-sulfur cluster biosynthetic enzyme
NLU04_RS23910	COG0822	iron-sulfur transferase activity
NLU04_RS23915	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NLU04_RS23920	COG0396	ATPase activity
NLU04_RS23930	COG0719	Fe-S assembly protein
NLU04_RS23945	COG1131	(ABC) transporter
NLU04_RS23960	COG2801	Transposase and inactivated derivatives
NLU04_RS23960	COG3415	Transposase
NLU04_RS23970	COG0109	protoheme IX farnesyltransferase activity
NLU04_RS23980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NLU04_RS23995	COG0363	glucosamine-6-phosphate deaminase activity
NLU04_RS24005	COG4195	phage-related replication protein
NLU04_RS24020	COG0166	Belongs to the GPI family
NLU04_RS24030	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NLU04_RS24035	COG0149	triose-phosphate isomerase activity
NLU04_RS24040	COG0126	phosphoglycerate kinase activity
NLU04_RS24045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NLU04_RS24050	COG1481	regulation of sporulation
NLU04_RS24055	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NLU04_RS24060	COG1660	Displays ATPase and GTPase activities
NLU04_RS24065	COG0322	excinuclease ABC activity
NLU04_RS24090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NLU04_RS24120	COG0556	nucleotide-excision repair
NLU04_RS24130	COG0584	glycerophosphoryl diester phosphodiesterase
NLU04_RS24135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NLU04_RS24140	COG2814	Major facilitator Superfamily
NLU04_RS24150	COG2313	pseudouridylate synthase activity
NLU04_RS24160	COG1473	amidohydrolase
NLU04_RS24180	COG0436	Aminotransferase
NLU04_RS24200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NLU04_RS24225	COG0237	dephospho-CoA kinase activity
NLU04_RS24245	COG2226	methyltransferase
NLU04_RS24250	COG1643	Atp-dependent helicase
NLU04_RS24285	COG2050	protein possibly involved in aromatic compounds catabolism
NLU04_RS24340	COG0737	Belongs to the 5'-nucleotidase family
NLU04_RS24360	COG0659	secondary active sulfate transmembrane transporter activity
NLU04_RS24370	COG2824	Alkylphosphonate utilization operon protein PhnA
NLU04_RS24385	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NLU04_RS24390	COG0287	Prephenate dehydrogenase
NLU04_RS24390	COG1605	Chorismate mutase
NLU04_RS24430	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS24435	COG1024	Enoyl-CoA hydratase
NLU04_RS24460	COG1278	Cold shock
NLU04_RS24465	COG0183	Belongs to the thiolase family
NLU04_RS24470	COG1309	transcriptional regulator
NLU04_RS24475	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS24480	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS24485	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS24500	COG2304	oxidoreductase activity
NLU04_RS24505	COG0705	Rhomboid family
NLU04_RS24515	COG0067	glutamate synthase
NLU04_RS24515	COG0069	glutamate synthase activity
NLU04_RS24515	COG0070	glutamate synthase
NLU04_RS24525	COG1397	ADP-ribosylglycohydrolase
NLU04_RS24545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLU04_RS24550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NLU04_RS24560	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NLU04_RS24570	COG0159	tryptophan synthase activity
NLU04_RS24575	COG0133	tryptophan synthase activity
NLU04_RS24585	COG0134	indole-3-glycerol-phosphate synthase activity
NLU04_RS24605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NLU04_RS24610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NLU04_RS24620	COG2508	Transcriptional regulator
NLU04_RS24635	COG0107	imidazoleglycerol-phosphate synthase activity
NLU04_RS24640	COG0251	oxidation-reduction process
NLU04_RS24645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NLU04_RS24650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NLU04_RS24660	COG0131	Imidazoleglycerol-phosphate dehydratase
NLU04_RS24665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NLU04_RS24670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NLU04_RS24685	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NLU04_RS24715	COG1432	Conserved Protein
NLU04_RS24725	COG0587	DNA-directed DNA polymerase activity
NLU04_RS24775	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NLU04_RS24785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NLU04_RS24790	COG3599	regulation of cell shape
NLU04_RS24800	COG1799	cell septum assembly
NLU04_RS24805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NLU04_RS24825	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NLU04_RS24835	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NLU04_RS24840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLU04_RS24850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NLU04_RS24855	COG0768	penicillin binding
NLU04_RS24865	COG0275	rRNA processing
NLU04_RS24875	COG0714	Associated with various cellular activities
NLU04_RS24895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NLU04_RS24905	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NLU04_RS24910	COG1511	domain protein
NLU04_RS24940	COG0352	thiamine-phosphate diphosphorylase activity
NLU04_RS24960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NLU04_RS24960	COG2022	thiamine diphosphate biosynthetic process
NLU04_RS24970	COG2022	thiamine diphosphate biosynthetic process
NLU04_RS24975	COG2815	serine threonine protein kinase
NLU04_RS24975	COG0515	serine threonine protein kinase
NLU04_RS24980	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NLU04_RS24985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NLU04_RS24990	COG2193	ferroxidase activity
NLU04_RS25000	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NLU04_RS25010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLU04_RS25015	COG2197	response regulator
NLU04_RS25020	COG4585	Histidine kinase
NLU04_RS25045	COG1940	carbohydrate kinase activity
NLU04_RS25055	COG0003	Pfam Anion-transporting ATPase
NLU04_RS25120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NLU04_RS25125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NLU04_RS25130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NLU04_RS25135	COG0723	plastoquinol--plastocyanin reductase activity
NLU04_RS25140	COG2010	Cytochrome c
NLU04_RS25145	COG1845	cytochrome c oxidase, subunit III
NLU04_RS25155	COG1376	ErfK ybiS ycfS ynhG family protein
NLU04_RS25165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NLU04_RS25170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NLU04_RS25175	COG1104	cysteine desulfurase activity
NLU04_RS25180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLU04_RS25200	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NLU04_RS25210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NLU04_RS25215	COG2197	response regulator
NLU04_RS25220	COG4585	Histidine kinase
NLU04_RS25245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NLU04_RS25260	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NLU04_RS25280	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NLU04_RS25285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NLU04_RS25290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NLU04_RS25295	COG0508	dehydrogenase complex catalyzes the overall conversion of
NLU04_RS25305	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NLU04_RS25325	COG1090	epimerase
NLU04_RS25340	COG0321	lipoyl(octanoyl) transferase activity
NLU04_RS25345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NLU04_RS25410	COG1846	Transcriptional regulator
NLU04_RS25445	COG0745	RESPONSE REGULATOR receiver
NLU04_RS25455	COG2197	response regulator
NLU04_RS25515	COG0366	Alpha amylase catalytic
NLU04_RS25520	COG3833	ABC-type maltose transport systems, permease component
NLU04_RS25525	COG1175	transmembrane transport
NLU04_RS25535	COG1609	Transcriptional regulator
NLU04_RS25550	COG0531	amino acid
NLU04_RS25560	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NLU04_RS25565	COG2890	protein-(glutamine-N5) methyltransferase activity
NLU04_RS25645	COG0174	glutamine synthetase
NLU04_RS25660	COG2132	Multicopper oxidase
NLU04_RS25665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NLU04_RS25665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NLU04_RS25670	COG2814	Major facilitator Superfamily
NLU04_RS25685	COG0477	Major facilitator Superfamily
NLU04_RS25690	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NLU04_RS25710	COG1994	Peptidase M50
NLU04_RS25745	COG5398	heme oxygenase
NLU04_RS25765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NLU04_RS25770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS25775	COG1120	ATPase activity
NLU04_RS25795	COG1834	amidinotransferase
NLU04_RS25810	COG2814	Major facilitator Superfamily
NLU04_RS25820	COG3540	Alkaline phosphatase
NLU04_RS25825	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS25835	COG0384	phenazine biosynthesis protein PhzF
NLU04_RS25860	COG2273	Hydrolase Family 16
NLU04_RS25890	COG3022	response to hydroperoxide
NLU04_RS25895	COG0800	Aldolase
NLU04_RS25915	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NLU04_RS25920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NLU04_RS25945	COG2030	dehydratase
NLU04_RS25955	COG0183	Belongs to the thiolase family
NLU04_RS25960	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS25965	COG3903	Transcriptional regulator
NLU04_RS25965	COG3629	intracellular signal transduction
NLU04_RS25980	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NLU04_RS25985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NLU04_RS25995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NLU04_RS26010	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS26020	COG0655	NAD(P)H dehydrogenase (quinone) activity
NLU04_RS26055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLU04_RS26085	COG0438	transferase activity, transferring glycosyl groups
NLU04_RS26090	COG1309	transcriptional regulator
NLU04_RS26160	COG3845	ABC transporter
NLU04_RS26170	COG0183	Belongs to the thiolase family
NLU04_RS26175	COG2124	cytochrome p450
NLU04_RS26225	COG2259	Doxx family
NLU04_RS26255	COG2801	Transposase and inactivated derivatives
NLU04_RS26255	COG3415	Transposase
NLU04_RS26270	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NLU04_RS26305	COG1358	cellular component organization or biogenesis
NLU04_RS26350	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NLU04_RS26360	COG0477	Major facilitator Superfamily
NLU04_RS26365	COG1309	transcriptional regulator
NLU04_RS26380	COG4585	Histidine kinase
NLU04_RS26385	COG2197	response regulator
NLU04_RS26400	COG0667	Aldo Keto reductase
NLU04_RS26405	COG0789	Transcriptional regulator
NLU04_RS26430	COG1741	Belongs to the pirin family
NLU04_RS26445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLU04_RS26450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLU04_RS26455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NLU04_RS26480	COG1309	transcriptional regulator
NLU04_RS26490	COG1764	response to oxidative stress
NLU04_RS26495	COG2130	NADP-dependent
NLU04_RS26525	COG1522	sequence-specific DNA binding
NLU04_RS26535	COG0318	PFAM AMP-dependent synthetase and ligase
NLU04_RS26540	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NLU04_RS26540	COG0825	malonyl-CoA metabolic process
NLU04_RS26550	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NLU04_RS26555	COG0438	transferase activity, transferring glycosyl groups
NLU04_RS26565	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NLU04_RS26590	COG1070	Carbohydrate kinase
NLU04_RS26605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NLU04_RS26610	COG0358	DNA primase activity
NLU04_RS26615	COG2226	methyltransferase
NLU04_RS26625	COG0477	Major facilitator Superfamily
NLU04_RS26635	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NLU04_RS26690	COG2146	nitrite reductase [NAD(P)H] activity
NLU04_RS26690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NLU04_RS26695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NLU04_RS26695	COG2146	nitrite reductase [NAD(P)H] activity
NLU04_RS26715	COG0574	Belongs to the PEP-utilizing enzyme family
NLU04_RS26715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NLU04_RS26725	COG3842	ATPase activity
NLU04_RS26745	COG2188	Transcriptional regulator
NLU04_RS26810	COG4942	peptidase
NLU04_RS26840	COG2066	Belongs to the glutaminase family
NLU04_RS26885	COG1733	regulation of RNA biosynthetic process
NLU04_RS26890	COG0702	epimerase
NLU04_RS26905	COG2197	response regulator
NLU04_RS26935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NLU04_RS26950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NLU04_RS26970	COG0423	glycine-tRNA ligase activity
NLU04_RS26975	COG3443	Belongs to the bacterial solute-binding protein 9 family
NLU04_RS26975	COG0803	Belongs to the bacterial solute-binding protein 9 family
NLU04_RS26980	COG1121	(ABC) transporter
NLU04_RS26985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NLU04_RS26995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NLU04_RS27000	COG1381	Involved in DNA repair and RecF pathway recombination
NLU04_RS27010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NLU04_RS27025	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NLU04_RS27035	COG2315	Protein conserved in bacteria
NLU04_RS27045	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NLU04_RS27055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLU04_RS27065	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NLU04_RS27070	COG1234	tRNA 3'-trailer cleavage
NLU04_RS27075	COG0537	adenosine 5'-monophosphoramidase activity
NLU04_RS27090	COG0484	heat shock protein binding
NLU04_RS27095	COG1420	regulation of RNA biosynthetic process
NLU04_RS27120	COG1022	Amp-dependent synthetase and ligase
NLU04_RS27125	COG0481	GTPase activity
NLU04_RS27130	COG0268	Binds directly to 16S ribosomal RNA
NLU04_RS27145	COG2353	YceI-like domain
NLU04_RS27155	COG1555	photosystem II stabilization
NLU04_RS27160	COG1307	EDD domain protein, DegV family
NLU04_RS27170	COG0495	leucyl-tRNA aminoacylation
NLU04_RS27205	COG0588	phosphoglycerate mutase activity
NLU04_RS27210	COG0799	negative regulation of ribosome biogenesis
NLU04_RS27220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NLU04_RS27235	COG0501	Belongs to the peptidase M48B family
NLU04_RS27250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NLU04_RS27260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NLU04_RS27285	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NLU04_RS27290	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NLU04_RS27295	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NLU04_RS27335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NLU04_RS27340	COG1530	ribonuclease E activity
NLU04_RS27365	COG0772	Belongs to the SEDS family
NLU04_RS27370	COG0768	penicillin binding
NLU04_RS27385	COG1077	Cell shape determining protein MreB Mrl
NLU04_RS27390	COG0105	UTP biosynthetic process
NLU04_RS27400	COG0285	dihydrofolate synthase activity
NLU04_RS27405	COG0525	valine-tRNA ligase activity
NLU04_RS27415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NLU04_RS27420	COG0740	serine-type endopeptidase activity
NLU04_RS27425	COG0740	serine-type endopeptidase activity
NLU04_RS27430	COG0544	peptidyl-prolyl cis-trans isomerase activity
NLU04_RS27450	COG3594	Acyltransferase
NLU04_RS27455	COG0475	glutathione-regulated potassium exporter activity
NLU04_RS27465	COG4552	Acetyltransferase involved in intracellular survival and related
NLU04_RS27480	COG1113	amino acid transport
NLU04_RS27485	COG1268	BioY protein
NLU04_RS27490	COG1113	amino acid transport
NLU04_RS27495	COG1113	amino acid transport
NLU04_RS27505	COG0783	Belongs to the Dps family
NLU04_RS27510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NLU04_RS27515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NLU04_RS27520	COG0640	Transcriptional regulator
NLU04_RS27535	COG0110	maltose O-acetyltransferase activity
NLU04_RS27545	COG3655	Transcriptional regulator
NLU04_RS27555	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS27570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NLU04_RS27605	COG4266	Belongs to the allantoicase family
NLU04_RS27630	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NLU04_RS27640	COG0668	transmembrane transport
NLU04_RS27645	COG1940	carbohydrate kinase activity
NLU04_RS27655	COG1175	transmembrane transport
NLU04_RS27660	COG0395	ABC-type sugar transport system, permease component
NLU04_RS27665	COG1486	melibiose metabolic process
NLU04_RS27680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NLU04_RS27710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NLU04_RS27715	COG2346	COG2346, Truncated hemoglobins
NLU04_RS27740	COG0629	single-stranded DNA binding
NLU04_RS27745	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NLU04_RS27780	COG4585	Histidine kinase
NLU04_RS27805	COG1131	(ABC) transporter
NLU04_RS27820	COG3962	Belongs to the TPP enzyme family
NLU04_RS27825	COG3718	enzyme involved in inositol metabolism
NLU04_RS27845	COG2318	DinB family
NLU04_RS27855	COG0500	methyltransferase
NLU04_RS27855	COG3615	Tellurite resistance protein tehB
NLU04_RS27860	COG2409	Drug exporters of the RND superfamily
NLU04_RS27885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NLU04_RS27960	COG1122	ATPase activity
NLU04_RS28005	COG0673	inositol 2-dehydrogenase activity
NLU04_RS28010	COG1609	Transcriptional regulator
NLU04_RS28035	COG0515	serine threonine protein kinase
NLU04_RS28070	COG1404	Belongs to the peptidase S8 family
NLU04_RS28115	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS28120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLU04_RS28125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLU04_RS28130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NLU04_RS28135	COG1472	Belongs to the glycosyl hydrolase 3 family
NLU04_RS28165	COG3960	tartronate-semialdehyde synthase activity
NLU04_RS28190	COG1396	sequence-specific DNA binding
NLU04_RS28210	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS28215	COG1946	Acyl-CoA thioesterase
NLU04_RS28235	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NLU04_RS28235	COG2755	lipolytic protein G-D-S-L family
NLU04_RS28260	COG1309	transcriptional regulator
NLU04_RS28265	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NLU04_RS28280	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS28295	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NLU04_RS28300	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NLU04_RS28305	COG3537	Alpha-1,2-mannosidase
NLU04_RS28320	COG0076	glutamate decarboxylase activity
NLU04_RS28325	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NLU04_RS28350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NLU04_RS28355	COG0589	response to stress
NLU04_RS28360	COG4977	sequence-specific DNA binding
NLU04_RS28390	COG0395	ABC-type sugar transport system, permease component
NLU04_RS28405	COG2985	domain, Protein
NLU04_RS28450	COG0588	phosphoglycerate mutase activity
NLU04_RS28505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLU04_RS28520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NLU04_RS28525	COG0765	amino acid transport
NLU04_RS28530	COG0765	amino acid transport
NLU04_RS28535	COG1126	abc transporter atp-binding protein
NLU04_RS28550	COG3397	chitin binding
NLU04_RS28575	COG3415	Transposase
NLU04_RS28575	COG2801	Transposase and inactivated derivatives
NLU04_RS28625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NLU04_RS28630	COG2188	Transcriptional regulator
NLU04_RS28660	COG0673	inositol 2-dehydrogenase activity
NLU04_RS28665	COG4702	Belongs to the UPF0303 family
NLU04_RS28675	COG0706	membrane insertase activity
NLU04_RS28675	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
NLU04_RS28685	COG3764	Sortase (surface protein transpeptidase)
NLU04_RS28715	COG0270	DNA (cytosine-5-)-methyltransferase activity
NLU04_RS28745	COG1074	ATP-dependent DNA helicase activity
NLU04_RS28775	COG1215	transferase activity, transferring glycosyl groups
NLU04_RS28785	COG0745	RESPONSE REGULATOR receiver
NLU04_RS28805	COG3409	Peptidoglycan-binding domain 1 protein
NLU04_RS28815	COG0789	Transcriptional regulator
NLU04_RS28845	COG0697	spore germination
NLU04_RS28860	COG2313	pseudouridylate synthase activity
NLU04_RS28865	COG2733	membrane
NLU04_RS28880	COG4555	ABC transporter
NLU04_RS28895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NLU04_RS28920	COG0477	Major facilitator Superfamily
NLU04_RS28930	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NLU04_RS28940	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NLU04_RS28945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NLU04_RS28950	COG1263	PTS System
NLU04_RS28955	COG1263	PTS System
NLU04_RS28960	COG1234	tRNA 3'-trailer cleavage
NLU04_RS28980	COG1120	ATPase activity
NLU04_RS28985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLU04_RS29000	COG1113	amino acid transport
NLU04_RS29010	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NLU04_RS29020	COG1335	isochorismatase
NLU04_RS29055	COG0277	FAD linked oxidase domain protein
NLU04_RS29065	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NLU04_RS29075	COG1174	glycine betaine transport
NLU04_RS29085	COG1174	glycine betaine transport
NLU04_RS29090	COG1732	Glycine betaine
NLU04_RS29095	COG3480	Lon protease (S16) C-terminal proteolytic domain
NLU04_RS29105	COG1061	Type III restriction enzyme res subunit
NLU04_RS29110	COG3654	unkown
NLU04_RS29150	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NLU04_RS29155	COG0395	ABC-type sugar transport system, permease component
NLU04_RS29175	COG1678	Uncharacterized ACR, COG1678
NLU04_RS29180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLU04_RS29185	COG0776	regulation of translation
NLU04_RS29195	COG3973	AAA domain
NLU04_RS29195	COG3973	AAA domain
NLU04_RS29225	COG2223	nitrite transmembrane transporter activity
NLU04_RS29230	COG0583	DNA-binding transcription factor activity
NLU04_RS29275	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NLU04_RS29280	COG0793	Belongs to the peptidase S41A family
NLU04_RS29285	COG2177	Part of the ABC transporter FtsEX involved in
NLU04_RS29290	COG2884	Cell division ATP-binding protein ftsE
NLU04_RS29305	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NLU04_RS29310	COG0515	serine threonine protein kinase
NLU04_RS29315	COG0515	serine threonine protein kinase
NLU04_RS29325	COG1653	transport
NLU04_RS29330	COG1175	transmembrane transport
NLU04_RS29335	COG0395	ABC-type sugar transport system, permease component
NLU04_RS29345	COG1309	transcriptional regulator
NLU04_RS29355	COG1134	teichoic acid transport
NLU04_RS29360	COG2902	Dehydrogenase
NLU04_RS29385	COG0653	protein targeting
NLU04_RS29400	COG2197	response regulator
NLU04_RS29405	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NLU04_RS29410	COG1040	competence protein
NLU04_RS29415	COG0823	Involved in the tonB-independent uptake of proteins
NLU04_RS29420	COG5000	phosphorelay sensor kinase activity
NLU04_RS29420	COG5002	protein histidine kinase activity
NLU04_RS29425	COG0745	RESPONSE REGULATOR receiver
NLU04_RS29430	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NLU04_RS29450	COG0714	Associated with various cellular activities
NLU04_RS29490	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NLU04_RS29500	COG1482	cell wall glycoprotein biosynthetic process
NLU04_RS29510	COG2835	tetraacyldisaccharide 4'-kinase activity
NLU04_RS29515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NLU04_RS29550	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NLU04_RS29555	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
NLU04_RS29555	COG0778	Nitroreductase
NLU04_RS29565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NLU04_RS29580	COG1316	TRANSCRIPTIONal
NLU04_RS29585	COG1316	TRANSCRIPTIONal
NLU04_RS29595	COG1316	TRANSCRIPTIONal
NLU04_RS29605	COG1316	TRANSCRIPTIONal
NLU04_RS29640	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NLU04_RS29680	COG2205	protein histidine kinase activity
NLU04_RS29685	COG0745	RESPONSE REGULATOR receiver
NLU04_RS29690	COG3104	oligopeptide transport
NLU04_RS29720	COG1366	Belongs to the anti-sigma-factor antagonist family
NLU04_RS29725	COG1191	sigma factor activity
NLU04_RS29730	COG1228	amidohydrolase
NLU04_RS29740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NLU04_RS29745	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NLU04_RS29750	COG0531	amino acid
NLU04_RS29795	COG2755	lipolytic protein G-D-S-L family
NLU04_RS29800	COG0183	Belongs to the thiolase family
NLU04_RS29825	COG0577	efflux transmembrane transporter activity
NLU04_RS29825	COG1136	(ABC) transporter
NLU04_RS29830	COG1136	(ABC) transporter
NLU04_RS29830	COG0577	efflux transmembrane transporter activity
NLU04_RS29835	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NLU04_RS29840	COG1252	NADH dehydrogenase
NLU04_RS29865	COG0148	phosphopyruvate hydratase activity
NLU04_RS29885	COG2124	cytochrome p450
NLU04_RS30035	COG1994	Peptidase M50
NLU04_RS30065	COG3903	Transcriptional regulator
NLU04_RS30065	COG3629	intracellular signal transduction
NLU04_RS30075	COG0577	efflux transmembrane transporter activity
NLU04_RS30080	COG1136	(ABC) transporter
NLU04_RS30090	COG0477	Major facilitator Superfamily
NLU04_RS30120	COG2124	cytochrome p450
NLU04_RS30155	COG4585	Histidine kinase
NLU04_RS30170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NLU04_RS30175	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLU04_RS30180	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NLU04_RS30185	COG0193	aminoacyl-tRNA hydrolase activity
NLU04_RS30195	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NLU04_RS30215	COG4106	trans-aconitate 2-methyltransferase activity
NLU04_RS30225	COG2197	response regulator
NLU04_RS30235	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NLU04_RS30250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLU04_RS30275	COG0488	(ABC) transporter
NLU04_RS30280	COG2161	toxin-antitoxin pair type II binding
NLU04_RS30285	COG4115	mRNA cleavage
NLU04_RS30305	COG2813	Specifically methylates the guanine in position
NLU04_RS30310	COG2318	DinB family
NLU04_RS30315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NLU04_RS30320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NLU04_RS30330	COG0084	hydrolase, TatD family'
NLU04_RS30405	COG0442	prolyl-tRNA aminoacylation
NLU04_RS30420	COG1115	amino acid carrier protein
NLU04_RS30450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NLU04_RS30455	COG1122	ATPase activity
NLU04_RS30465	COG0310	cobalt ion transport
NLU04_RS30475	COG2409	Drug exporters of the RND superfamily
NLU04_RS30485	COG4946	Tricorn protease homolog
NLU04_RS30485	COG0793	Belongs to the peptidase S41A family
NLU04_RS30500	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS30510	COG2072	flavoprotein involved in K transport
NLU04_RS30520	COG0708	Exodeoxyribonuclease III
NLU04_RS30530	COG2340	Cysteine-rich secretory protein family
NLU04_RS30560	COG0521	Mo-molybdopterin cofactor biosynthetic process
NLU04_RS30565	COG0315	cyclic pyranopterin monophosphate synthase activity
NLU04_RS30575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NLU04_RS30580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NLU04_RS30605	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NLU04_RS30615	COG1970	mechanosensitive ion channel activity
NLU04_RS30635	COG0437	4 iron, 4 sulfur cluster binding
NLU04_RS30640	COG0243	molybdopterin cofactor binding
NLU04_RS30660	COG0477	Major facilitator Superfamily
NLU04_RS30680	COG3384	dioxygenase
NLU04_RS30685	COG1846	Transcriptional regulator
NLU04_RS30715	COG2197	response regulator
NLU04_RS30745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NLU04_RS30750	COG0475	glutathione-regulated potassium exporter activity
NLU04_RS30775	COG0463	Glycosyl transferase, family 2
NLU04_RS30820	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NLU04_RS30830	COG4974	Belongs to the 'phage' integrase family
NLU04_RS30875	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NLU04_RS30915	COG1011	Hydrolase
NLU04_RS30955	COG0242	peptide deformylase activity
NLU04_RS31005	COG1686	Belongs to the peptidase S11 family
NLU04_RS31035	COG1397	ADP-ribosylglycohydrolase
NLU04_RS31055	COG3655	Transcriptional regulator
NLU04_RS31085	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NLU04_RS31095	COG0768	penicillin binding
NLU04_RS31130	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NLU04_RS31155	COG0667	Aldo Keto reductase
NLU04_RS31160	COG1309	transcriptional regulator
NLU04_RS31265	COG0183	Belongs to the thiolase family
NLU04_RS31270	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS31285	COG1309	transcriptional regulator
NLU04_RS31315	COG0318	PFAM AMP-dependent synthetase and ligase
NLU04_RS31330	COG1301	dicarboxylic acid transport
NLU04_RS31345	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NLU04_RS31360	COG0163	prenyltransferase activity
NLU04_RS31370	COG0109	protoheme IX farnesyltransferase activity
NLU04_RS31375	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NLU04_RS31385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NLU04_RS31390	COG1333	cytochrome c biogenesis protein
NLU04_RS31395	COG0785	Cytochrome C biogenesis protein
NLU04_RS31410	COG2382	esterase
NLU04_RS31415	COG0406	alpha-ribazole phosphatase activity
NLU04_RS31420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NLU04_RS31465	COG1690	Belongs to the RtcB family
NLU04_RS31485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NLU04_RS31490	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
NLU04_RS31495	COG0018	arginyl-trna synthetase
NLU04_RS31505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NLU04_RS31545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NLU04_RS31575	COG0113	porphobilinogen synthase activity
NLU04_RS31580	COG1648	precorrin-2 dehydrogenase activity
NLU04_RS31580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NLU04_RS31585	COG0181	hydroxymethylbilane synthase activity
NLU04_RS31590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NLU04_RS31595	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NLU04_RS31650	COG2223	nitrite transmembrane transporter activity
NLU04_RS31655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NLU04_RS31675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLU04_RS31685	COG1129	ABC transporter
NLU04_RS31685	COG0842	Transport permease protein
NLU04_RS31695	COG4991	sh3 domain protein
NLU04_RS31705	COG0129	dihydroxy-acid dehydratase activity
NLU04_RS31715	COG1082	Xylose isomerase domain protein TIM barrel
NLU04_RS31720	COG0248	Ppx GppA phosphatase
NLU04_RS31740	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NLU04_RS31750	COG1194	a g-specific adenine glycosylase
NLU04_RS31755	COG1595	DNA-templated transcription, initiation
NLU04_RS31765	COG0745	RESPONSE REGULATOR receiver
NLU04_RS31770	COG2205	protein histidine kinase activity
NLU04_RS31775	COG0739	heme binding
NLU04_RS31815	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NLU04_RS31835	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NLU04_RS31845	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NLU04_RS31850	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NLU04_RS31875	COG2197	response regulator
NLU04_RS31890	COG0649	NAD binding
NLU04_RS31905	COG1174	glycine betaine transport
NLU04_RS31910	COG1174	glycine betaine transport
NLU04_RS31915	COG0517	IMP dehydrogenase activity
NLU04_RS31915	COG1125	glycine betaine transport
NLU04_RS31925	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NLU04_RS31925	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NLU04_RS31940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NLU04_RS31955	COG0302	gtp cyclohydrolase
NLU04_RS31970	COG0037	tRNA processing
NLU04_RS31980	COG2027	D-alanyl-D-alanine carboxypeptidase
NLU04_RS31985	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NLU04_RS31995	COG0586	Pfam SNARE associated Golgi protein
NLU04_RS32010	COG0655	NAD(P)H dehydrogenase (quinone) activity
NLU04_RS32015	COG0076	glutamate decarboxylase activity
NLU04_RS32035	COG1012	belongs to the aldehyde dehydrogenase family
NLU04_RS32070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLU04_RS32070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLU04_RS32100	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NLU04_RS32110	COG1725	Transcriptional regulator
NLU04_RS32130	COG0326	Molecular chaperone. Has ATPase activity
NLU04_RS32140	COG2205	protein histidine kinase activity
NLU04_RS32160	COG0372	Belongs to the citrate synthase family
NLU04_RS32175	COG4948	Mandelate Racemase Muconate Lactonizing
NLU04_RS32180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NLU04_RS32185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLU04_RS32200	COG1181	Belongs to the D-alanine--D-alanine ligase family
NLU04_RS32215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLU04_RS32220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NLU04_RS32225	COG1754	DNA topoisomerase type I activity
NLU04_RS32225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NLU04_RS32235	COG2890	protein-(glutamine-N5) methyltransferase activity
NLU04_RS32245	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NLU04_RS32255	COG1366	Belongs to the anti-sigma-factor antagonist family
NLU04_RS32260	COG1111	helicase
NLU04_RS32260	COG1205	dead DEAH box helicase
NLU04_RS32320	COG0288	reversible hydration of carbon dioxide
NLU04_RS32325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NLU04_RS32330	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NLU04_RS32340	COG2267	carboxylic ester hydrolase activity
NLU04_RS32370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NLU04_RS32395	COG0003	Pfam Anion-transporting ATPase
NLU04_RS32405	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NLU04_RS32410	COG1610	YqeY-like protein
NLU04_RS32415	COG1408	metallophosphoesterase
NLU04_RS32515	COG2755	lipolytic protein G-D-S-L family
NLU04_RS32525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NLU04_RS32545	COG1595	DNA-templated transcription, initiation
NLU04_RS32570	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NLU04_RS32575	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NLU04_RS32590	COG1802	Transcriptional regulator
NLU04_RS32600	COG0693	protein deglycase activity
NLU04_RS32620	COG0738	Major facilitator superfamily
NLU04_RS32630	COG3226	Transcriptional regulator
NLU04_RS32645	COG0592	DNA-directed DNA polymerase activity
NLU04_RS32655	COG0667	Aldo Keto reductase
NLU04_RS32680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NLU04_RS32690	COG0662	Cupin 2, conserved barrel domain protein
NLU04_RS32695	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS32750	COG2076	Multidrug Resistance protein
NLU04_RS32755	COG0590	tRNA wobble adenosine to inosine editing
NLU04_RS32765	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NLU04_RS32770	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NLU04_RS32795	COG2197	response regulator
NLU04_RS32805	COG0702	epimerase
NLU04_RS32815	COG3844	kynureninase activity
NLU04_RS32830	COG0477	Major facilitator Superfamily
NLU04_RS32835	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NLU04_RS32840	COG0191	fructose-bisphosphate aldolase activity
NLU04_RS32845	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NLU04_RS32860	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NLU04_RS32885	COG0542	response to heat
NLU04_RS32915	COG0789	Transcriptional regulator
NLU04_RS32920	COG0484	heat shock protein binding
NLU04_RS32925	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NLU04_RS32930	COG0443	Heat shock 70 kDa protein
NLU04_RS32935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NLU04_RS32940	COG2181	nitrate reductase activity
NLU04_RS32940	COG0247	lactate metabolic process
NLU04_RS32960	COG0717	Belongs to the dCTP deaminase family
NLU04_RS33035	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NLU04_RS33085	COG1309	transcriptional regulator
NLU04_RS33090	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS33105	COG2197	response regulator
NLU04_RS33125	COG2205	protein histidine kinase activity
NLU04_RS33130	COG0745	RESPONSE REGULATOR receiver
NLU04_RS33145	COG1376	ErfK ybiS ycfS ynhG family protein
NLU04_RS33150	COG3046	protein related to deoxyribodipyrimidine photolyase
NLU04_RS33155	COG1533	DNA photolyase activity
NLU04_RS33165	COG2130	NADP-dependent
NLU04_RS33185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NLU04_RS33235	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS33250	COG0367	asparagine synthase
NLU04_RS33265	COG1902	pentaerythritol trinitrate reductase activity
NLU04_RS33300	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS33315	COG0745	RESPONSE REGULATOR receiver
NLU04_RS33325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NLU04_RS33335	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NLU04_RS33350	COG0519	Catalyzes the synthesis of GMP from XMP
NLU04_RS33350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NLU04_RS33360	COG0318	PFAM AMP-dependent synthetase and ligase
NLU04_RS33375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLU04_RS33390	COG1695	Transcriptional regulator
NLU04_RS33400	COG0667	Aldo Keto reductase
NLU04_RS33410	COG1609	Transcriptional regulator
NLU04_RS33435	COG2124	cytochrome p450
NLU04_RS33440	COG2124	cytochrome p450
NLU04_RS33465	COG3585	molybdate ion transport
NLU04_RS33500	COG2801	Transposase and inactivated derivatives
NLU04_RS33500	COG3415	Transposase
NLU04_RS33505	COG0475	glutathione-regulated potassium exporter activity
NLU04_RS33520	COG0513	Belongs to the DEAD box helicase family
NLU04_RS33525	COG1278	Cold shock
NLU04_RS33565	COG0454	-acetyltransferase
NLU04_RS33590	COG2268	Band 7 protein
NLU04_RS33620	COG0490	domain, Protein
NLU04_RS33625	COG0475	glutathione-regulated potassium exporter activity
NLU04_RS33650	COG2255	four-way junction helicase activity
NLU04_RS33660	COG0180	Tryptophanyl-tRNA synthetase
NLU04_RS33670	COG2015	COG2015, Alkyl sulfatase and related hydrolases
NLU04_RS33675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLU04_RS33705	COG0431	NADPH-dependent FMN reductase
NLU04_RS33735	COG2304	oxidoreductase activity
NLU04_RS33740	COG2205	protein histidine kinase activity
NLU04_RS33745	COG0745	RESPONSE REGULATOR receiver
NLU04_RS33750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLU04_RS33765	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NLU04_RS33780	COG1741	Belongs to the pirin family
NLU04_RS33790	COG1960	acyl-CoA dehydrogenase activity
NLU04_RS33795	COG1362	aminopeptidase activity
NLU04_RS33815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NLU04_RS33855	COG0508	dehydrogenase complex catalyzes the overall conversion of
NLU04_RS33860	COG0022	dehydrogenase e1 component
NLU04_RS33885	COG0515	serine threonine protein kinase
NLU04_RS33890	COG0515	serine threonine protein kinase
NLU04_RS33905	COG4591	ABC-type transport system involved in lipoprotein release permease component
NLU04_RS33905	COG1136	(ABC) transporter
NLU04_RS33920	COG0604	alcohol dehydrogenase
NLU04_RS33920	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS33920	COG3321	synthase
NLU04_RS33925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NLU04_RS33935	COG0746	molybdenum cofactor guanylyltransferase activity
NLU04_RS33955	COG1522	sequence-specific DNA binding
NLU04_RS33960	COG1309	transcriptional regulator
NLU04_RS33985	COG3396	Phenylacetate-CoA oxygenase
NLU04_RS34005	COG1857	crispr-associated protein
NLU04_RS34020	COG1518	maintenance of DNA repeat elements
NLU04_RS34025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NLU04_RS34030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLU04_RS34035	COG0587	DNA-directed DNA polymerase activity
NLU04_RS34045	COG0640	Transcriptional regulator
NLU04_RS34060	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NLU04_RS34080	COG1191	sigma factor activity
NLU04_RS34120	COG0187	DNA topoisomerase II activity
NLU04_RS34160	COG1122	ATPase activity
NLU04_RS34215	COG2409	Drug exporters of the RND superfamily
NLU04_RS34225	COG3293	Transposase
NLU04_RS34245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NLU04_RS34255	COG0446	pyridine nucleotide-disulphide oxidoreductase
NLU04_RS34265	COG3938	Belongs to the proline racemase family
NLU04_RS34270	COG3938	Belongs to the proline racemase family
NLU04_RS34280	COG1802	Transcriptional regulator
NLU04_RS34285	COG0006	proline dipeptidase activity
NLU04_RS34290	COG0747	negative chemotaxis
NLU04_RS34295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLU04_RS34300	COG0601	transmembrane transport
NLU04_RS34310	COG4608	Belongs to the ABC transporter superfamily
NLU04_RS34340	COG3291	Pkd domain containing protein
NLU04_RS34595	COG1028	Short-chain dehydrogenase reductase Sdr
NLU04_RS34605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NLU04_RS34670	COG1793	dna ligase
NLU04_RS34670	COG3285	dna ligase
NLU04_RS34765	COG1192	Involved in chromosome partitioning