locus-tag	class	description
OUQ49_RS00070	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OUQ49_RS00075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS00155	COG0789	Transcriptional regulator
OUQ49_RS00160	COG0659	secondary active sulfate transmembrane transporter activity
OUQ49_RS00175	COG1191	sigma factor activity
OUQ49_RS00195	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OUQ49_RS00210	COG0640	Transcriptional regulator
OUQ49_RS00220	COG0587	DNA-directed DNA polymerase activity
OUQ49_RS00230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OUQ49_RS00235	COG1518	maintenance of DNA repeat elements
OUQ49_RS00250	COG1857	crispr-associated protein
OUQ49_RS00295	COG0367	asparagine synthase
OUQ49_RS00300	COG0477	Major facilitator Superfamily
OUQ49_RS00305	COG2050	protein possibly involved in aromatic compounds catabolism
OUQ49_RS00315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OUQ49_RS00320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OUQ49_RS00330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OUQ49_RS00335	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS00410	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OUQ49_RS00415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OUQ49_RS00425	COG1846	Transcriptional regulator
OUQ49_RS00430	COG1764	response to oxidative stress
OUQ49_RS00440	COG0789	Transcriptional regulator
OUQ49_RS00465	COG0277	FAD linked oxidase domain protein
OUQ49_RS00475	COG1902	pentaerythritol trinitrate reductase activity
OUQ49_RS00480	COG0640	Transcriptional regulator
OUQ49_RS00485	COG1064	alcohol dehydrogenase
OUQ49_RS00505	COG0702	epimerase
OUQ49_RS00535	COG0642	Histidine kinase
OUQ49_RS00555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OUQ49_RS00560	COG0366	Alpha amylase catalytic
OUQ49_RS00565	COG0395	ABC-type sugar transport system, permease component
OUQ49_RS00570	COG1175	transmembrane transport
OUQ49_RS00620	COG1349	DNA-binding transcription factor activity
OUQ49_RS00625	COG1105	Belongs to the carbohydrate kinase PfkB family
OUQ49_RS00700	COG0254	rRNA binding
OUQ49_RS00760	COG1024	Enoyl-CoA hydratase
OUQ49_RS00785	COG0765	amino acid transport
OUQ49_RS00795	COG0318	PFAM AMP-dependent synthetase and ligase
OUQ49_RS00800	COG2366	antibiotic biosynthetic process
OUQ49_RS00810	COG2070	2-Nitropropane dioxygenase
OUQ49_RS00825	COG0515	serine threonine protein kinase
OUQ49_RS00835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OUQ49_RS00840	COG0346	lactoylglutathione lyase activity
OUQ49_RS00855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OUQ49_RS00865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OUQ49_RS00865	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OUQ49_RS00865	COG3321	synthase
OUQ49_RS00865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OUQ49_RS00865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OUQ49_RS00865	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OUQ49_RS00865	COG3321	synthase
OUQ49_RS00865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OUQ49_RS00870	COG3321	synthase
OUQ49_RS00870	COG0318	PFAM AMP-dependent synthetase and ligase
OUQ49_RS00870	COG0300	oxidoreductase activity
OUQ49_RS00870	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS00870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OUQ49_RS00875	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS00880	COG2813	Specifically methylates the guanine in position
OUQ49_RS00895	COG2356	endonuclease I
OUQ49_RS00900	COG2066	Belongs to the glutaminase family
OUQ49_RS00900	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
OUQ49_RS00915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OUQ49_RS00920	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
OUQ49_RS00925	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS00935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OUQ49_RS00940	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OUQ49_RS00945	COG2080	2 iron, 2 sulfur cluster binding
OUQ49_RS01005	COG2365	Tyrosine phosphatase family
OUQ49_RS01030	COG1120	ATPase activity
OUQ49_RS01035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OUQ49_RS01045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OUQ49_RS01060	COG2382	esterase
OUQ49_RS01065	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS01070	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS01075	COG1169	isochorismate synthase
OUQ49_RS01080	COG1021	2,3-dihydroxybenzoate-AMP ligase
OUQ49_RS01085	COG3433	isochorismatase activity
OUQ49_RS01085	COG1535	isochorismatase
OUQ49_RS01090	COG1535	isochorismatase
OUQ49_RS01090	COG3433	isochorismatase activity
OUQ49_RS01170	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OUQ49_RS01205	COG3845	ABC transporter
OUQ49_RS01230	COG1470	cell adhesion involved in biofilm formation
OUQ49_RS01250	COG1132	(ABC) transporter
OUQ49_RS01265	COG1063	alcohol dehydrogenase
OUQ49_RS01270	COG0395	ABC-type sugar transport system, permease component
OUQ49_RS01285	COG1349	DNA-binding transcription factor activity
OUQ49_RS01315	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OUQ49_RS01335	COG2382	esterase
OUQ49_RS01340	COG1132	(ABC) transporter
OUQ49_RS01350	COG1132	(ABC) transporter
OUQ49_RS01360	COG1120	ATPase activity
OUQ49_RS01365	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS01370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS01375	COG3486	L-lysine 6-monooxygenase (NADPH) activity
OUQ49_RS01460	COG0640	Transcriptional regulator
OUQ49_RS01495	COG1132	(ABC) transporter
OUQ49_RS01500	COG1132	(ABC) transporter
OUQ49_RS01505	COG1181	Belongs to the D-alanine--D-alanine ligase family
OUQ49_RS01520	COG1181	Belongs to the D-alanine--D-alanine ligase family
OUQ49_RS01540	COG0504	CTP synthase activity
OUQ49_RS01545	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OUQ49_RS01550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OUQ49_RS01555	COG2197	response regulator
OUQ49_RS01560	COG0640	Transcriptional regulator
OUQ49_RS01565	COG0243	molybdopterin cofactor binding
OUQ49_RS01590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OUQ49_RS01595	COG0573	inorganic phosphate transmembrane transporter activity
OUQ49_RS01600	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OUQ49_RS01605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OUQ49_RS01610	COG0798	PFAM Bile acid sodium symporter
OUQ49_RS01620	COG2226	methyltransferase
OUQ49_RS01630	COG0583	DNA-binding transcription factor activity
OUQ49_RS01635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OUQ49_RS01645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OUQ49_RS01655	COG1116	anion transmembrane transporter activity
OUQ49_RS01700	COG0640	Transcriptional regulator
OUQ49_RS01730	COG1191	sigma factor activity
OUQ49_RS01770	COG0297	glycogen (starch) synthase activity
OUQ49_RS01790	COG0531	amino acid
OUQ49_RS01840	COG2376	Dihydroxyacetone kinase
OUQ49_RS01845	COG1461	Dihydroxyacetone kinase
OUQ49_RS01860	COG0488	(ABC) transporter
OUQ49_RS01890	COG1191	sigma factor activity
OUQ49_RS01900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OUQ49_RS01905	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OUQ49_RS01920	COG1120	ATPase activity
OUQ49_RS01925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS01950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OUQ49_RS01995	COG1063	alcohol dehydrogenase
OUQ49_RS02000	COG1295	ribonuclease BN
OUQ49_RS02000	COG1959	2 iron, 2 sulfur cluster binding
OUQ49_RS02030	COG2837	iron assimilation
OUQ49_RS02035	COG1120	ATPase activity
OUQ49_RS02040	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS02045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS02065	COG0617	tRNA 3'-terminal CCA addition
OUQ49_RS02070	COG2207	Transcriptional regulator
OUQ49_RS02085	COG0366	Alpha amylase catalytic
OUQ49_RS02085	COG1874	Beta-galactosidase
OUQ49_RS02100	COG1609	Transcriptional regulator
OUQ49_RS02105	COG1172	Belongs to the binding-protein-dependent transport system permease family
OUQ49_RS02115	COG1129	ABC transporter
OUQ49_RS02120	COG1879	ABC-type sugar transport system periplasmic component
OUQ49_RS02125	COG3250	beta-galactosidase activity
OUQ49_RS02165	COG0328	RNA-DNA hybrid ribonuclease activity
OUQ49_RS02170	COG1132	(ABC) transporter
OUQ49_RS02180	COG2264	protein methyltransferase activity
OUQ49_RS02225	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS02230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OUQ49_RS02270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OUQ49_RS02285	COG2045	Belongs to the ComB family
OUQ49_RS02305	COG0464	growth
OUQ49_RS02315	COG1349	DNA-binding transcription factor activity
OUQ49_RS02330	COG0702	epimerase
OUQ49_RS02370	COG1940	carbohydrate kinase activity
OUQ49_RS02375	COG2223	nitrite transmembrane transporter activity
OUQ49_RS02415	COG0445	tRNA wobble uridine modification
OUQ49_RS02430	COG1660	Displays ATPase and GTPase activities
OUQ49_RS02435	COG1940	carbohydrate kinase activity
OUQ49_RS02470	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OUQ49_RS02515	COG0584	glycerophosphoryl diester phosphodiesterase
OUQ49_RS02520	COG0456	acetyltransferase
OUQ49_RS02535	COG0671	phosphoesterase, PA-phosphatase related
OUQ49_RS02585	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OUQ49_RS02590	COG2971	BadF BadG BcrA BcrD
OUQ49_RS02600	COG2706	6-phosphogluconolactonase activity
OUQ49_RS02620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OUQ49_RS02625	COG0515	serine threonine protein kinase
OUQ49_RS02625	COG2815	serine threonine protein kinase
OUQ49_RS02630	COG0667	Aldo Keto reductase
OUQ49_RS02660	COG1253	flavin adenine dinucleotide binding
OUQ49_RS02700	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OUQ49_RS02705	COG0531	amino acid
OUQ49_RS02710	COG2186	Transcriptional regulator
OUQ49_RS02715	COG0174	glutamine synthetase
OUQ49_RS02720	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS02730	COG1609	Transcriptional regulator
OUQ49_RS02735	COG1653	transport
OUQ49_RS02740	COG1175	transmembrane transport
OUQ49_RS02750	COG1472	Belongs to the glycosyl hydrolase 3 family
OUQ49_RS02780	COG4981	capsule polysaccharide biosynthetic process
OUQ49_RS02800	COG2835	tetraacyldisaccharide 4'-kinase activity
OUQ49_RS02810	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS02825	COG0243	molybdopterin cofactor binding
OUQ49_RS02850	COG1357	PFAM Pentapeptide repeats (8 copies)
OUQ49_RS02855	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS02860	COG1982	Orn Lys Arg decarboxylase major
OUQ49_RS02925	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS02930	COG2124	cytochrome p450
OUQ49_RS02945	COG1335	isochorismatase
OUQ49_RS03000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OUQ49_RS03010	COG0542	response to heat
OUQ49_RS03025	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS03030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS03040	COG4592	Periplasmic binding protein
OUQ49_RS03070	COG0385	Bile acid
OUQ49_RS03095	COG0583	DNA-binding transcription factor activity
OUQ49_RS03115	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OUQ49_RS03135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OUQ49_RS03140	COG1116	anion transmembrane transporter activity
OUQ49_RS03150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUQ49_RS03155	COG2072	flavoprotein involved in K transport
OUQ49_RS03170	COG1132	(ABC) transporter
OUQ49_RS03180	COG0277	FAD linked oxidase domain protein
OUQ49_RS03190	COG1132	(ABC) transporter
OUQ49_RS03195	COG1132	(ABC) transporter
OUQ49_RS03220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OUQ49_RS03220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OUQ49_RS03235	COG1252	NADH dehydrogenase
OUQ49_RS03240	COG1793	dna ligase
OUQ49_RS03255	COG1946	Acyl-CoA thioesterase
OUQ49_RS03270	COG0386	Belongs to the glutathione peroxidase family
OUQ49_RS03275	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS03285	COG0242	peptide deformylase activity
OUQ49_RS03295	COG3442	glutamine amidotransferase
OUQ49_RS03300	COG0205	6-phosphofructokinase activity
OUQ49_RS03330	COG0829	nickel cation binding
OUQ49_RS03335	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OUQ49_RS03345	COG0804	urea catabolic process
OUQ49_RS03350	COG0832	Belongs to the urease beta subunit family
OUQ49_RS03355	COG0831	urea catabolic process
OUQ49_RS03400	COG0156	8-amino-7-oxononanoate synthase activity
OUQ49_RS03405	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OUQ49_RS03410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OUQ49_RS03415	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OUQ49_RS03420	COG2226	methyltransferase
OUQ49_RS03445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OUQ49_RS03450	COG3663	DNA glycosylase
OUQ49_RS03460	COG1940	carbohydrate kinase activity
OUQ49_RS03465	COG2188	Transcriptional regulator
OUQ49_RS03470	COG1595	DNA-templated transcription, initiation
OUQ49_RS03500	COG0626	cystathionine gamma-synthase activity
OUQ49_RS03520	COG1522	sequence-specific DNA binding
OUQ49_RS03525	COG0419	ATPase involved in DNA repair
OUQ49_RS03530	COG0420	3'-5' exonuclease activity
OUQ49_RS03535	COG1739	Uncharacterized protein family UPF0029
OUQ49_RS03540	COG1832	CoA-binding protein
OUQ49_RS03580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OUQ49_RS03595	COG1968	undecaprenyl-diphosphatase activity
OUQ49_RS03605	COG2226	methyltransferase
OUQ49_RS03610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OUQ49_RS03660	COG2318	DinB family
OUQ49_RS03675	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OUQ49_RS03750	COG1404	Belongs to the peptidase S8 family
OUQ49_RS03805	COG0583	DNA-binding transcription factor activity
OUQ49_RS03835	COG0697	spore germination
OUQ49_RS03875	COG1695	Transcriptional regulator
OUQ49_RS03920	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OUQ49_RS03920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OUQ49_RS03930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OUQ49_RS03950	COG1716	ATPase activity
OUQ49_RS03970	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OUQ49_RS04000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OUQ49_RS04010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OUQ49_RS04025	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
OUQ49_RS04055	COG2018	Roadblock/LC7 domain
OUQ49_RS04120	COG2364	Membrane
OUQ49_RS04130	COG2270	Major facilitator Superfamily
OUQ49_RS04140	COG3030	protein affecting phage T7 exclusion by the F plasmid
OUQ49_RS04145	COG1216	Glycosyl transferase, family 2
OUQ49_RS04165	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS04210	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OUQ49_RS04215	COG0140	phosphoribosyl-ATP diphosphatase activity
OUQ49_RS04220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OUQ49_RS04230	COG3201	nicotinamide mononucleotide transporter
OUQ49_RS04255	COG0738	Major facilitator superfamily
OUQ49_RS04260	COG2233	PERMEase
OUQ49_RS04275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OUQ49_RS04285	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS04300	COG2390	Transcriptional regulator
OUQ49_RS04305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OUQ49_RS04315	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OUQ49_RS04330	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OUQ49_RS04340	COG1758	RNA polymerase activity
OUQ49_RS04355	COG0284	orotidine-5'-phosphate decarboxylase activity
OUQ49_RS04360	COG0167	dihydroorotate dehydrogenase activity
OUQ49_RS04365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OUQ49_RS04370	COG0505	Belongs to the CarA family
OUQ49_RS04380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OUQ49_RS04385	COG0540	Belongs to the ATCase OTCase family
OUQ49_RS04390	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OUQ49_RS04400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OUQ49_RS04405	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OUQ49_RS04410	COG0006	proline dipeptidase activity
OUQ49_RS04420	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OUQ49_RS04425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OUQ49_RS04430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OUQ49_RS04435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OUQ49_RS04445	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OUQ49_RS04450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OUQ49_RS04470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OUQ49_RS04490	COG0124	histidyl-tRNA synthetase
OUQ49_RS04505	COG1196	nuclear chromosome segregation
OUQ49_RS04510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OUQ49_RS04515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OUQ49_RS04520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OUQ49_RS04525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OUQ49_RS04535	COG2255	four-way junction helicase activity
OUQ49_RS04540	COG0632	four-way junction helicase activity
OUQ49_RS04550	COG0217	transcriptional regulatory protein
OUQ49_RS04555	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OUQ49_RS04560	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OUQ49_RS04570	COG0438	transferase activity, transferring glycosyl groups
OUQ49_RS04575	COG1560	Kdo2-lipid A biosynthetic process
OUQ49_RS04580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OUQ49_RS04605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OUQ49_RS04620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OUQ49_RS04680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OUQ49_RS04735	COG1648	precorrin-2 dehydrogenase activity
OUQ49_RS04735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OUQ49_RS04740	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OUQ49_RS04755	COG1464	Belongs to the NlpA lipoprotein family
OUQ49_RS04760	COG2011	ABC-type metal ion transport system permease component
OUQ49_RS04800	COG0477	Major facilitator Superfamily
OUQ49_RS04810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OUQ49_RS04815	COG3973	AAA domain
OUQ49_RS04825	COG0165	Argininosuccinate lyase
OUQ49_RS04830	COG0137	argininosuccinate synthase activity
OUQ49_RS04840	COG1438	arginine binding
OUQ49_RS04845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OUQ49_RS04850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OUQ49_RS04855	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OUQ49_RS04860	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OUQ49_RS04910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OUQ49_RS04925	COG0697	spore germination
OUQ49_RS04935	COG1649	PFAM Uncharacterised BCR, COG1649
OUQ49_RS04955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OUQ49_RS04955	COG0072	phenylalanine-tRNA ligase activity
OUQ49_RS04960	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OUQ49_RS04965	COG5002	protein histidine kinase activity
OUQ49_RS04970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OUQ49_RS04975	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OUQ49_RS04980	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OUQ49_RS04985	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OUQ49_RS05045	COG4175	Glycine betaine
OUQ49_RS05045	COG0517	IMP dehydrogenase activity
OUQ49_RS05050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OUQ49_RS05075	COG1595	DNA-templated transcription, initiation
OUQ49_RS05095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OUQ49_RS05100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OUQ49_RS05140	COG0805	protein transport
OUQ49_RS05145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OUQ49_RS05165	COG2378	regulation of single-species biofilm formation
OUQ49_RS05175	COG0545	Peptidyl-prolyl cis-trans isomerase
OUQ49_RS05180	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OUQ49_RS05190	COG1609	Transcriptional regulator
OUQ49_RS05195	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OUQ49_RS05200	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OUQ49_RS05215	COG4122	O-methyltransferase activity
OUQ49_RS05220	COG1222	aaa ATPase
OUQ49_RS05240	COG0517	IMP dehydrogenase activity
OUQ49_RS05240	COG1994	Peptidase M50
OUQ49_RS05250	COG2197	response regulator
OUQ49_RS05255	COG4166	transmembrane transport
OUQ49_RS05265	COG1410	methionine synthase
OUQ49_RS05265	COG0646	methionine synthase
OUQ49_RS05270	COG1414	Transcriptional regulator
OUQ49_RS05275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OUQ49_RS05280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OUQ49_RS05285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OUQ49_RS05290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUQ49_RS05300	COG0215	cysteine-tRNA ligase activity
OUQ49_RS05320	COG0598	Magnesium transport protein CorA
OUQ49_RS05330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUQ49_RS05335	COG0667	Aldo Keto reductase
OUQ49_RS05370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OUQ49_RS05380	COG0564	pseudouridine synthase activity
OUQ49_RS05395	COG2186	Transcriptional regulator
OUQ49_RS05400	COG3265	gluconokinase activity
OUQ49_RS05425	COG3573	Dehydrogenase
OUQ49_RS05430	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
OUQ49_RS05435	COG2149	membrane
OUQ49_RS05455	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS05460	COG4935	Belongs to the peptidase S8 family
OUQ49_RS05460	COG2234	aminopeptidase activity
OUQ49_RS05470	COG0318	PFAM AMP-dependent synthetase and ligase
OUQ49_RS05475	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS05480	COG3876	Protein conserved in bacteria
OUQ49_RS05500	COG0789	Transcriptional regulator
OUQ49_RS05520	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS05530	COG2326	polyphosphate kinase activity
OUQ49_RS05555	COG2851	Citrate transporter
OUQ49_RS05560	COG0243	molybdopterin cofactor binding
OUQ49_RS05565	COG1309	transcriptional regulator
OUQ49_RS05570	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OUQ49_RS05575	COG2188	Transcriptional regulator
OUQ49_RS05585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OUQ49_RS05595	COG2755	lipolytic protein G-D-S-L family
OUQ49_RS05605	COG1725	Transcriptional regulator
OUQ49_RS05620	COG0346	lactoylglutathione lyase activity
OUQ49_RS05640	COG4565	transcriptional regulatory protein
OUQ49_RS05775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OUQ49_RS05780	COG0587	DNA-directed DNA polymerase activity
OUQ49_RS05810	COG0641	radical SAM
OUQ49_RS05840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUQ49_RS05850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUQ49_RS05870	COG0765	amino acid transport
OUQ49_RS05875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUQ49_RS05885	COG1799	cell septum assembly
OUQ49_RS05890	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS05895	COG0477	Major facilitator Superfamily
OUQ49_RS05900	COG0671	phosphoesterase, PA-phosphatase related
OUQ49_RS05920	COG0438	transferase activity, transferring glycosyl groups
OUQ49_RS05935	COG1160	GTP binding
OUQ49_RS05945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OUQ49_RS05965	COG3541	Predicted nucleotidyltransferase
OUQ49_RS05970	COG3541	Predicted nucleotidyltransferase
OUQ49_RS05980	COG0494	nUDIX hydrolase
OUQ49_RS05995	COG1187	pseudouridine synthase activity
OUQ49_RS06000	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OUQ49_RS06005	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OUQ49_RS06020	COG0686	Belongs to the AlaDH PNT family
OUQ49_RS06030	COG0494	nUDIX hydrolase
OUQ49_RS06035	COG0504	CTP synthase activity
OUQ49_RS06040	COG3387	PFAM Glycoside hydrolase 15-related
OUQ49_RS06060	COG3119	arylsulfatase activity
OUQ49_RS06065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OUQ49_RS06075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OUQ49_RS06080	COG0601	transmembrane transport
OUQ49_RS06085	COG4166	transmembrane transport
OUQ49_RS06110	COG0497	DNA recombination
OUQ49_RS06115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OUQ49_RS06135	COG1120	ATPase activity
OUQ49_RS06140	COG0647	UMP catabolic process
OUQ49_RS06175	COG2094	Belongs to the DNA glycosylase MPG family
OUQ49_RS06185	COG1881	PFAM PEBP family protein
OUQ49_RS06210	COG1119	ATPase activity
OUQ49_RS06220	COG2197	response regulator
OUQ49_RS06235	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OUQ49_RS06245	COG1131	(ABC) transporter
OUQ49_RS06245	COG0842	Transport permease protein
OUQ49_RS06245	COG1716	ATPase activity
OUQ49_RS06250	COG0560	Phosphoserine phosphatase
OUQ49_RS06250	COG3830	Belongs to the UPF0237 family
OUQ49_RS06275	COG2186	Transcriptional regulator
OUQ49_RS06285	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OUQ49_RS06290	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS06305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OUQ49_RS06310	COG2261	transglycosylase associated protein
OUQ49_RS06325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OUQ49_RS06330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OUQ49_RS06360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OUQ49_RS06375	COG3387	PFAM Glycoside hydrolase 15-related
OUQ49_RS06415	COG1024	Enoyl-CoA hydratase
OUQ49_RS06425	COG0488	(ABC) transporter
OUQ49_RS06450	COG0235	Class ii aldolase
OUQ49_RS06465	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OUQ49_RS06470	COG1492	cobalamin metabolic process
OUQ49_RS06485	COG1797	cobyrinic acid a,c-diamide synthase activity
OUQ49_RS06510	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OUQ49_RS06540	COG1902	pentaerythritol trinitrate reductase activity
OUQ49_RS06545	COG1846	Transcriptional regulator
OUQ49_RS06575	COG0768	penicillin binding
OUQ49_RS06580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUQ49_RS06590	COG0431	NADPH-dependent FMN reductase
OUQ49_RS06605	COG0583	DNA-binding transcription factor activity
OUQ49_RS06640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OUQ49_RS06645	COG2171	N-acyltransferase activity
OUQ49_RS06660	COG3226	Transcriptional regulator
OUQ49_RS06680	COG2151	metal-sulfur cluster biosynthetic enzyme
OUQ49_RS06685	COG0822	iron-sulfur transferase activity
OUQ49_RS06690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OUQ49_RS06695	COG0396	ATPase activity
OUQ49_RS06705	COG0719	Fe-S assembly protein
OUQ49_RS06720	COG1131	(ABC) transporter
OUQ49_RS06740	COG0109	protoheme IX farnesyltransferase activity
OUQ49_RS06750	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OUQ49_RS06765	COG0363	glucosamine-6-phosphate deaminase activity
OUQ49_RS06775	COG4195	phage-related replication protein
OUQ49_RS06790	COG0166	Belongs to the GPI family
OUQ49_RS06800	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OUQ49_RS06805	COG0149	triose-phosphate isomerase activity
OUQ49_RS06810	COG0126	phosphoglycerate kinase activity
OUQ49_RS06815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OUQ49_RS06820	COG1481	regulation of sporulation
OUQ49_RS06825	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OUQ49_RS06830	COG1660	Displays ATPase and GTPase activities
OUQ49_RS06835	COG0322	excinuclease ABC activity
OUQ49_RS06860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OUQ49_RS06890	COG0556	nucleotide-excision repair
OUQ49_RS06900	COG0584	glycerophosphoryl diester phosphodiesterase
OUQ49_RS06905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OUQ49_RS06910	COG2814	Major facilitator Superfamily
OUQ49_RS06920	COG2313	pseudouridylate synthase activity
OUQ49_RS06930	COG1473	amidohydrolase
OUQ49_RS06950	COG0436	Aminotransferase
OUQ49_RS06970	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OUQ49_RS06995	COG0237	dephospho-CoA kinase activity
OUQ49_RS07015	COG2226	methyltransferase
OUQ49_RS07020	COG1643	Atp-dependent helicase
OUQ49_RS07055	COG2050	protein possibly involved in aromatic compounds catabolism
OUQ49_RS07110	COG0737	Belongs to the 5'-nucleotidase family
OUQ49_RS07130	COG0659	secondary active sulfate transmembrane transporter activity
OUQ49_RS07140	COG2824	Alkylphosphonate utilization operon protein PhnA
OUQ49_RS07155	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OUQ49_RS07160	COG0287	Prephenate dehydrogenase
OUQ49_RS07160	COG1605	Chorismate mutase
OUQ49_RS07200	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS07205	COG1024	Enoyl-CoA hydratase
OUQ49_RS07230	COG1278	Cold shock
OUQ49_RS07235	COG0183	Belongs to the thiolase family
OUQ49_RS07240	COG1309	transcriptional regulator
OUQ49_RS07250	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS07255	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS07270	COG2304	oxidoreductase activity
OUQ49_RS07275	COG0705	Rhomboid family
OUQ49_RS07285	COG0070	glutamate synthase
OUQ49_RS07285	COG0069	glutamate synthase activity
OUQ49_RS07285	COG0067	glutamate synthase
OUQ49_RS07295	COG1397	ADP-ribosylglycohydrolase
OUQ49_RS07315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OUQ49_RS07320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OUQ49_RS07330	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OUQ49_RS07340	COG0159	tryptophan synthase activity
OUQ49_RS07345	COG0133	tryptophan synthase activity
OUQ49_RS07355	COG0134	indole-3-glycerol-phosphate synthase activity
OUQ49_RS07375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OUQ49_RS07380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OUQ49_RS07390	COG2508	Transcriptional regulator
OUQ49_RS07405	COG0107	imidazoleglycerol-phosphate synthase activity
OUQ49_RS07410	COG0251	oxidation-reduction process
OUQ49_RS07415	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OUQ49_RS07420	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OUQ49_RS07430	COG0131	Imidazoleglycerol-phosphate dehydratase
OUQ49_RS07435	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OUQ49_RS07440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OUQ49_RS07455	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OUQ49_RS07485	COG1432	Conserved Protein
OUQ49_RS07495	COG0587	DNA-directed DNA polymerase activity
OUQ49_RS07545	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OUQ49_RS07555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OUQ49_RS07560	COG3599	regulation of cell shape
OUQ49_RS07570	COG1799	cell septum assembly
OUQ49_RS07575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OUQ49_RS07595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OUQ49_RS07605	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OUQ49_RS07610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OUQ49_RS07620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OUQ49_RS07635	COG0275	rRNA processing
OUQ49_RS07645	COG0714	Associated with various cellular activities
OUQ49_RS07665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OUQ49_RS07675	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OUQ49_RS07680	COG1511	domain protein
OUQ49_RS07710	COG0352	thiamine-phosphate diphosphorylase activity
OUQ49_RS07730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OUQ49_RS07730	COG2022	thiamine diphosphate biosynthetic process
OUQ49_RS07740	COG2022	thiamine diphosphate biosynthetic process
OUQ49_RS07745	COG0515	serine threonine protein kinase
OUQ49_RS07745	COG2815	serine threonine protein kinase
OUQ49_RS07750	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OUQ49_RS07755	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OUQ49_RS07760	COG2193	ferroxidase activity
OUQ49_RS07770	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OUQ49_RS07780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OUQ49_RS07785	COG2197	response regulator
OUQ49_RS07790	COG4585	Histidine kinase
OUQ49_RS07815	COG1940	carbohydrate kinase activity
OUQ49_RS07825	COG0003	Pfam Anion-transporting ATPase
OUQ49_RS07890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OUQ49_RS07895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OUQ49_RS07900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OUQ49_RS07905	COG0723	plastoquinol--plastocyanin reductase activity
OUQ49_RS07910	COG2010	Cytochrome c
OUQ49_RS07915	COG1845	cytochrome c oxidase, subunit III
OUQ49_RS07925	COG1376	ErfK ybiS ycfS ynhG family protein
OUQ49_RS07935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OUQ49_RS07940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OUQ49_RS07945	COG1104	cysteine desulfurase activity
OUQ49_RS07950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OUQ49_RS07970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OUQ49_RS07980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OUQ49_RS07985	COG2197	response regulator
OUQ49_RS07990	COG4585	Histidine kinase
OUQ49_RS08015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OUQ49_RS08030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OUQ49_RS08050	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
OUQ49_RS08055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OUQ49_RS08060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OUQ49_RS08065	COG0508	dehydrogenase complex catalyzes the overall conversion of
OUQ49_RS08075	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OUQ49_RS08095	COG1090	epimerase
OUQ49_RS08110	COG0321	lipoyl(octanoyl) transferase activity
OUQ49_RS08115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OUQ49_RS08180	COG1846	Transcriptional regulator
OUQ49_RS08215	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS08225	COG2197	response regulator
OUQ49_RS08285	COG0366	Alpha amylase catalytic
OUQ49_RS08290	COG3833	ABC-type maltose transport systems, permease component
OUQ49_RS08295	COG1175	transmembrane transport
OUQ49_RS08305	COG1609	Transcriptional regulator
OUQ49_RS08320	COG0531	amino acid
OUQ49_RS08330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OUQ49_RS08335	COG2890	protein-(glutamine-N5) methyltransferase activity
OUQ49_RS08405	COG0174	glutamine synthetase
OUQ49_RS08420	COG2132	Multicopper oxidase
OUQ49_RS08425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OUQ49_RS08425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OUQ49_RS08430	COG2814	Major facilitator Superfamily
OUQ49_RS08445	COG0477	Major facilitator Superfamily
OUQ49_RS08450	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OUQ49_RS08470	COG1994	Peptidase M50
OUQ49_RS08505	COG5398	heme oxygenase
OUQ49_RS08525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OUQ49_RS08530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS08535	COG1120	ATPase activity
OUQ49_RS08555	COG1834	amidinotransferase
OUQ49_RS08570	COG2814	Major facilitator Superfamily
OUQ49_RS08580	COG3540	Alkaline phosphatase
OUQ49_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS08595	COG0384	phenazine biosynthesis protein PhzF
OUQ49_RS08620	COG2273	Hydrolase Family 16
OUQ49_RS08650	COG3022	response to hydroperoxide
OUQ49_RS08655	COG0800	Aldolase
OUQ49_RS08675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OUQ49_RS08680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OUQ49_RS08705	COG2030	dehydratase
OUQ49_RS08715	COG0183	Belongs to the thiolase family
OUQ49_RS08720	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS08725	COG3629	intracellular signal transduction
OUQ49_RS08725	COG3903	Transcriptional regulator
OUQ49_RS08740	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OUQ49_RS08745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OUQ49_RS08755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OUQ49_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS08780	COG0655	NAD(P)H dehydrogenase (quinone) activity
OUQ49_RS08815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUQ49_RS08845	COG0438	transferase activity, transferring glycosyl groups
OUQ49_RS08850	COG1309	transcriptional regulator
OUQ49_RS08920	COG3845	ABC transporter
OUQ49_RS08930	COG0183	Belongs to the thiolase family
OUQ49_RS08935	COG2124	cytochrome p450
OUQ49_RS08985	COG2259	Doxx family
OUQ49_RS09020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OUQ49_RS09055	COG1358	cellular component organization or biogenesis
OUQ49_RS09100	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OUQ49_RS09110	COG0477	Major facilitator Superfamily
OUQ49_RS09115	COG1309	transcriptional regulator
OUQ49_RS09130	COG4585	Histidine kinase
OUQ49_RS09135	COG2197	response regulator
OUQ49_RS09150	COG0667	Aldo Keto reductase
OUQ49_RS09155	COG0789	Transcriptional regulator
OUQ49_RS09180	COG1741	Belongs to the pirin family
OUQ49_RS09195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OUQ49_RS09200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OUQ49_RS09205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OUQ49_RS09230	COG1309	transcriptional regulator
OUQ49_RS09240	COG1764	response to oxidative stress
OUQ49_RS09245	COG2130	NADP-dependent
OUQ49_RS09275	COG1522	sequence-specific DNA binding
OUQ49_RS09285	COG0318	PFAM AMP-dependent synthetase and ligase
OUQ49_RS09290	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OUQ49_RS09290	COG0825	malonyl-CoA metabolic process
OUQ49_RS09300	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OUQ49_RS09305	COG0438	transferase activity, transferring glycosyl groups
OUQ49_RS09315	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OUQ49_RS09340	COG1070	Carbohydrate kinase
OUQ49_RS09355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OUQ49_RS09360	COG0358	DNA primase activity
OUQ49_RS09365	COG2226	methyltransferase
OUQ49_RS09375	COG0477	Major facilitator Superfamily
OUQ49_RS09385	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OUQ49_RS09440	COG2146	nitrite reductase [NAD(P)H] activity
OUQ49_RS09440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OUQ49_RS09445	COG2146	nitrite reductase [NAD(P)H] activity
OUQ49_RS09445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OUQ49_RS09465	COG0574	Belongs to the PEP-utilizing enzyme family
OUQ49_RS09465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OUQ49_RS09475	COG3842	ATPase activity
OUQ49_RS09495	COG2188	Transcriptional regulator
OUQ49_RS09560	COG4942	peptidase
OUQ49_RS09565	COG2801	Transposase and inactivated derivatives
OUQ49_RS09565	COG3415	Transposase
OUQ49_RS09590	COG2066	Belongs to the glutaminase family
OUQ49_RS09635	COG1733	regulation of RNA biosynthetic process
OUQ49_RS09640	COG0702	epimerase
OUQ49_RS09655	COG2197	response regulator
OUQ49_RS09685	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OUQ49_RS09695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OUQ49_RS09715	COG0423	glycine-tRNA ligase activity
OUQ49_RS09720	COG3443	Belongs to the bacterial solute-binding protein 9 family
OUQ49_RS09720	COG0803	Belongs to the bacterial solute-binding protein 9 family
OUQ49_RS09725	COG1121	(ABC) transporter
OUQ49_RS09730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OUQ49_RS09740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OUQ49_RS09745	COG1381	Involved in DNA repair and RecF pathway recombination
OUQ49_RS09755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OUQ49_RS09770	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OUQ49_RS09780	COG2315	Protein conserved in bacteria
OUQ49_RS09790	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OUQ49_RS09800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OUQ49_RS09810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OUQ49_RS09815	COG1234	tRNA 3'-trailer cleavage
OUQ49_RS09820	COG0537	adenosine 5'-monophosphoramidase activity
OUQ49_RS09835	COG0484	heat shock protein binding
OUQ49_RS09840	COG1420	regulation of RNA biosynthetic process
OUQ49_RS09865	COG1022	Amp-dependent synthetase and ligase
OUQ49_RS09870	COG0481	GTPase activity
OUQ49_RS09875	COG0268	Binds directly to 16S ribosomal RNA
OUQ49_RS09890	COG2353	YceI-like domain
OUQ49_RS09900	COG1555	photosystem II stabilization
OUQ49_RS09905	COG1307	EDD domain protein, DegV family
OUQ49_RS09915	COG0495	leucyl-tRNA aminoacylation
OUQ49_RS09950	COG0588	phosphoglycerate mutase activity
OUQ49_RS09955	COG0799	negative regulation of ribosome biogenesis
OUQ49_RS09965	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OUQ49_RS09980	COG0501	Belongs to the peptidase M48B family
OUQ49_RS09995	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OUQ49_RS10005	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OUQ49_RS10030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OUQ49_RS10035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OUQ49_RS10040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OUQ49_RS10080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OUQ49_RS10110	COG0772	Belongs to the SEDS family
OUQ49_RS10115	COG0768	penicillin binding
OUQ49_RS10130	COG1077	Cell shape determining protein MreB Mrl
OUQ49_RS10135	COG0105	UTP biosynthetic process
OUQ49_RS10145	COG0285	dihydrofolate synthase activity
OUQ49_RS10150	COG0525	valine-tRNA ligase activity
OUQ49_RS10160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OUQ49_RS10165	COG0740	serine-type endopeptidase activity
OUQ49_RS10170	COG0740	serine-type endopeptidase activity
OUQ49_RS10175	COG0544	peptidyl-prolyl cis-trans isomerase activity
OUQ49_RS10195	COG3594	Acyltransferase
OUQ49_RS10200	COG0475	glutathione-regulated potassium exporter activity
OUQ49_RS10210	COG4552	Acetyltransferase involved in intracellular survival and related
OUQ49_RS10225	COG1113	amino acid transport
OUQ49_RS10230	COG1268	BioY protein
OUQ49_RS10235	COG1113	amino acid transport
OUQ49_RS10240	COG1113	amino acid transport
OUQ49_RS10250	COG0783	Belongs to the Dps family
OUQ49_RS10255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OUQ49_RS10260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OUQ49_RS10265	COG0640	Transcriptional regulator
OUQ49_RS10280	COG0110	maltose O-acetyltransferase activity
OUQ49_RS10290	COG3655	Transcriptional regulator
OUQ49_RS10300	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS10315	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OUQ49_RS10350	COG4266	Belongs to the allantoicase family
OUQ49_RS10375	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OUQ49_RS10385	COG0668	transmembrane transport
OUQ49_RS10390	COG1940	carbohydrate kinase activity
OUQ49_RS10400	COG1175	transmembrane transport
OUQ49_RS10405	COG0395	ABC-type sugar transport system, permease component
OUQ49_RS10410	COG1486	melibiose metabolic process
OUQ49_RS10425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUQ49_RS10455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OUQ49_RS10460	COG2346	COG2346, Truncated hemoglobins
OUQ49_RS10485	COG0629	single-stranded DNA binding
OUQ49_RS10490	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OUQ49_RS10545	COG2197	response regulator
OUQ49_RS10550	COG4585	Histidine kinase
OUQ49_RS10575	COG1131	(ABC) transporter
OUQ49_RS10590	COG3962	Belongs to the TPP enzyme family
OUQ49_RS10595	COG3718	enzyme involved in inositol metabolism
OUQ49_RS10615	COG2318	DinB family
OUQ49_RS10625	COG0500	methyltransferase
OUQ49_RS10625	COG3615	Tellurite resistance protein tehB
OUQ49_RS10630	COG2409	Drug exporters of the RND superfamily
OUQ49_RS10655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OUQ49_RS10690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OUQ49_RS10695	COG1396	sequence-specific DNA binding
OUQ49_RS10720	COG1122	ATPase activity
OUQ49_RS10760	COG0673	inositol 2-dehydrogenase activity
OUQ49_RS10765	COG1609	Transcriptional regulator
OUQ49_RS10790	COG0515	serine threonine protein kinase
OUQ49_RS10825	COG1404	Belongs to the peptidase S8 family
OUQ49_RS10870	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS10875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OUQ49_RS10880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OUQ49_RS10885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OUQ49_RS10890	COG1472	Belongs to the glycosyl hydrolase 3 family
OUQ49_RS10920	COG3960	tartronate-semialdehyde synthase activity
OUQ49_RS10945	COG1396	sequence-specific DNA binding
OUQ49_RS10965	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS10970	COG1946	Acyl-CoA thioesterase
OUQ49_RS10990	COG2755	lipolytic protein G-D-S-L family
OUQ49_RS10990	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OUQ49_RS10995	COG0515	serine threonine protein kinase
OUQ49_RS10995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OUQ49_RS11010	COG1309	transcriptional regulator
OUQ49_RS11015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OUQ49_RS11030	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS11060	COG1434	Gram-negative-bacterium-type cell wall biogenesis
OUQ49_RS11070	COG3537	Alpha-1,2-mannosidase
OUQ49_RS11085	COG0076	glutamate decarboxylase activity
OUQ49_RS11090	COG3486	L-lysine 6-monooxygenase (NADPH) activity
OUQ49_RS11115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OUQ49_RS11120	COG0589	response to stress
OUQ49_RS11125	COG4977	sequence-specific DNA binding
OUQ49_RS11155	COG0395	ABC-type sugar transport system, permease component
OUQ49_RS11170	COG2985	domain, Protein
OUQ49_RS11210	COG0588	phosphoglycerate mutase activity
OUQ49_RS11265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUQ49_RS11280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUQ49_RS11285	COG0765	amino acid transport
OUQ49_RS11290	COG0765	amino acid transport
OUQ49_RS11295	COG1126	abc transporter atp-binding protein
OUQ49_RS11310	COG3397	chitin binding
OUQ49_RS11390	COG2188	Transcriptional regulator
OUQ49_RS11420	COG0673	inositol 2-dehydrogenase activity
OUQ49_RS11425	COG4702	Belongs to the UPF0303 family
OUQ49_RS11435	COG0706	membrane insertase activity
OUQ49_RS11435	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
OUQ49_RS11445	COG3764	Sortase (surface protein transpeptidase)
OUQ49_RS11490	COG1215	transferase activity, transferring glycosyl groups
OUQ49_RS11500	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS11520	COG3409	Peptidoglycan-binding domain 1 protein
OUQ49_RS11530	COG0789	Transcriptional regulator
OUQ49_RS11565	COG0697	spore germination
OUQ49_RS11580	COG2313	pseudouridylate synthase activity
OUQ49_RS11585	COG2733	membrane
OUQ49_RS11600	COG4555	ABC transporter
OUQ49_RS11615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OUQ49_RS11640	COG0477	Major facilitator Superfamily
OUQ49_RS11650	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OUQ49_RS11660	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OUQ49_RS11665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OUQ49_RS11670	COG1263	PTS System
OUQ49_RS11675	COG1263	PTS System
OUQ49_RS11680	COG1234	tRNA 3'-trailer cleavage
OUQ49_RS11705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS11720	COG1113	amino acid transport
OUQ49_RS11730	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OUQ49_RS11740	COG1335	isochorismatase
OUQ49_RS11775	COG0277	FAD linked oxidase domain protein
OUQ49_RS11785	COG3185	4-Hydroxyphenylpyruvate dioxygenase
OUQ49_RS11795	COG1174	glycine betaine transport
OUQ49_RS11805	COG1174	glycine betaine transport
OUQ49_RS11810	COG1732	Glycine betaine
OUQ49_RS11815	COG3480	Lon protease (S16) C-terminal proteolytic domain
OUQ49_RS11825	COG1061	Type III restriction enzyme res subunit
OUQ49_RS11830	COG3654	unkown
OUQ49_RS11885	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OUQ49_RS11890	COG0395	ABC-type sugar transport system, permease component
OUQ49_RS11910	COG1678	Uncharacterized ACR, COG1678
OUQ49_RS11915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OUQ49_RS11920	COG0776	regulation of translation
OUQ49_RS11930	COG3973	AAA domain
OUQ49_RS11930	COG3973	AAA domain
OUQ49_RS11960	COG2223	nitrite transmembrane transporter activity
OUQ49_RS11965	COG0583	DNA-binding transcription factor activity
OUQ49_RS12010	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OUQ49_RS12015	COG0793	Belongs to the peptidase S41A family
OUQ49_RS12020	COG2177	Part of the ABC transporter FtsEX involved in
OUQ49_RS12025	COG2884	Cell division ATP-binding protein ftsE
OUQ49_RS12040	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OUQ49_RS12045	COG0515	serine threonine protein kinase
OUQ49_RS12050	COG0515	serine threonine protein kinase
OUQ49_RS12060	COG1653	transport
OUQ49_RS12065	COG1175	transmembrane transport
OUQ49_RS12070	COG0395	ABC-type sugar transport system, permease component
OUQ49_RS12080	COG1309	transcriptional regulator
OUQ49_RS12090	COG1134	teichoic acid transport
OUQ49_RS12095	COG2902	Dehydrogenase
OUQ49_RS12120	COG0653	protein targeting
OUQ49_RS12135	COG2197	response regulator
OUQ49_RS12140	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OUQ49_RS12145	COG1040	competence protein
OUQ49_RS12150	COG0823	Involved in the tonB-independent uptake of proteins
OUQ49_RS12155	COG5002	protein histidine kinase activity
OUQ49_RS12155	COG5000	phosphorelay sensor kinase activity
OUQ49_RS12160	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS12165	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OUQ49_RS12185	COG0714	Associated with various cellular activities
OUQ49_RS12225	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OUQ49_RS12235	COG1482	cell wall glycoprotein biosynthetic process
OUQ49_RS12245	COG2835	tetraacyldisaccharide 4'-kinase activity
OUQ49_RS12250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OUQ49_RS12285	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OUQ49_RS12290	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
OUQ49_RS12290	COG0778	Nitroreductase
OUQ49_RS12300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OUQ49_RS12315	COG1316	TRANSCRIPTIONal
OUQ49_RS12320	COG1316	TRANSCRIPTIONal
OUQ49_RS12330	COG1316	TRANSCRIPTIONal
OUQ49_RS12340	COG1316	TRANSCRIPTIONal
OUQ49_RS12375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OUQ49_RS12415	COG2205	protein histidine kinase activity
OUQ49_RS12420	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS12425	COG3104	oligopeptide transport
OUQ49_RS12455	COG1366	Belongs to the anti-sigma-factor antagonist family
OUQ49_RS12460	COG1191	sigma factor activity
OUQ49_RS12465	COG1228	amidohydrolase
OUQ49_RS12475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OUQ49_RS12480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OUQ49_RS12530	COG2755	lipolytic protein G-D-S-L family
OUQ49_RS12535	COG0183	Belongs to the thiolase family
OUQ49_RS12560	COG1136	(ABC) transporter
OUQ49_RS12560	COG0577	efflux transmembrane transporter activity
OUQ49_RS12565	COG1136	(ABC) transporter
OUQ49_RS12565	COG0577	efflux transmembrane transporter activity
OUQ49_RS12570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OUQ49_RS12575	COG1252	NADH dehydrogenase
OUQ49_RS12600	COG0148	phosphopyruvate hydratase activity
OUQ49_RS12620	COG2124	cytochrome p450
OUQ49_RS12770	COG1994	Peptidase M50
OUQ49_RS12800	COG3629	intracellular signal transduction
OUQ49_RS12800	COG3903	Transcriptional regulator
OUQ49_RS12810	COG0577	efflux transmembrane transporter activity
OUQ49_RS12815	COG1136	(ABC) transporter
OUQ49_RS12825	COG0477	Major facilitator Superfamily
OUQ49_RS12855	COG2124	cytochrome p450
OUQ49_RS12890	COG4585	Histidine kinase
OUQ49_RS12905	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OUQ49_RS12910	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OUQ49_RS12915	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OUQ49_RS12920	COG0193	aminoacyl-tRNA hydrolase activity
OUQ49_RS12930	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OUQ49_RS12950	COG4106	trans-aconitate 2-methyltransferase activity
OUQ49_RS12960	COG2197	response regulator
OUQ49_RS12970	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OUQ49_RS12985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OUQ49_RS13010	COG0488	(ABC) transporter
OUQ49_RS13015	COG2161	toxin-antitoxin pair type II binding
OUQ49_RS13020	COG4115	mRNA cleavage
OUQ49_RS13040	COG2813	Specifically methylates the guanine in position
OUQ49_RS13045	COG2318	DinB family
OUQ49_RS13050	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OUQ49_RS13055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OUQ49_RS13065	COG0084	hydrolase, TatD family'
OUQ49_RS13140	COG0442	prolyl-tRNA aminoacylation
OUQ49_RS13155	COG1115	amino acid carrier protein
OUQ49_RS13185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OUQ49_RS13190	COG1122	ATPase activity
OUQ49_RS13200	COG0310	cobalt ion transport
OUQ49_RS13210	COG2409	Drug exporters of the RND superfamily
OUQ49_RS13220	COG0793	Belongs to the peptidase S41A family
OUQ49_RS13220	COG4946	Tricorn protease homolog
OUQ49_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS13245	COG2072	flavoprotein involved in K transport
OUQ49_RS13255	COG0708	Exodeoxyribonuclease III
OUQ49_RS13265	COG2340	Cysteine-rich secretory protein family
OUQ49_RS13295	COG0521	Mo-molybdopterin cofactor biosynthetic process
OUQ49_RS13300	COG0315	cyclic pyranopterin monophosphate synthase activity
OUQ49_RS13310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OUQ49_RS13315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OUQ49_RS13340	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OUQ49_RS13350	COG1970	mechanosensitive ion channel activity
OUQ49_RS13370	COG0437	4 iron, 4 sulfur cluster binding
OUQ49_RS13375	COG0243	molybdopterin cofactor binding
OUQ49_RS13395	COG0477	Major facilitator Superfamily
OUQ49_RS13415	COG3384	dioxygenase
OUQ49_RS13420	COG1846	Transcriptional regulator
OUQ49_RS13450	COG2197	response regulator
OUQ49_RS13480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OUQ49_RS13485	COG0475	glutathione-regulated potassium exporter activity
OUQ49_RS13510	COG0463	Glycosyl transferase, family 2
OUQ49_RS13540	COG3629	intracellular signal transduction
OUQ49_RS13540	COG3903	Transcriptional regulator
OUQ49_RS13550	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OUQ49_RS13590	COG1686	Belongs to the peptidase S11 family
OUQ49_RS13620	COG1397	ADP-ribosylglycohydrolase
OUQ49_RS13640	COG3655	Transcriptional regulator
OUQ49_RS13670	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
OUQ49_RS13680	COG0768	penicillin binding
OUQ49_RS13740	COG0667	Aldo Keto reductase
OUQ49_RS13745	COG1309	transcriptional regulator
OUQ49_RS13860	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
OUQ49_RS13870	COG0183	Belongs to the thiolase family
OUQ49_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS13890	COG1309	transcriptional regulator
OUQ49_RS13920	COG0318	PFAM AMP-dependent synthetase and ligase
OUQ49_RS13935	COG1301	dicarboxylic acid transport
OUQ49_RS13950	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
OUQ49_RS13965	COG0163	prenyltransferase activity
OUQ49_RS13975	COG0109	protoheme IX farnesyltransferase activity
OUQ49_RS13980	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OUQ49_RS13990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OUQ49_RS13995	COG1333	cytochrome c biogenesis protein
OUQ49_RS14000	COG0785	Cytochrome C biogenesis protein
OUQ49_RS14015	COG2382	esterase
OUQ49_RS14020	COG0406	alpha-ribazole phosphatase activity
OUQ49_RS14025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OUQ49_RS14070	COG1690	Belongs to the RtcB family
OUQ49_RS14090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OUQ49_RS14095	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
OUQ49_RS14100	COG0018	arginyl-trna synthetase
OUQ49_RS14110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OUQ49_RS14145	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OUQ49_RS14175	COG0113	porphobilinogen synthase activity
OUQ49_RS14180	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OUQ49_RS14180	COG1648	precorrin-2 dehydrogenase activity
OUQ49_RS14185	COG0181	hydroxymethylbilane synthase activity
OUQ49_RS14190	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OUQ49_RS14195	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OUQ49_RS14250	COG2223	nitrite transmembrane transporter activity
OUQ49_RS14255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OUQ49_RS14275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OUQ49_RS14285	COG0842	Transport permease protein
OUQ49_RS14285	COG1129	ABC transporter
OUQ49_RS14295	COG4991	sh3 domain protein
OUQ49_RS14305	COG0129	dihydroxy-acid dehydratase activity
OUQ49_RS14315	COG1082	Xylose isomerase domain protein TIM barrel
OUQ49_RS14320	COG0248	Ppx GppA phosphatase
OUQ49_RS14340	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OUQ49_RS14350	COG1194	a g-specific adenine glycosylase
OUQ49_RS14355	COG1595	DNA-templated transcription, initiation
OUQ49_RS14365	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS14370	COG2205	protein histidine kinase activity
OUQ49_RS14375	COG0739	heme binding
OUQ49_RS14410	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OUQ49_RS14430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OUQ49_RS14440	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OUQ49_RS14445	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OUQ49_RS14470	COG2197	response regulator
OUQ49_RS14485	COG0649	NAD binding
OUQ49_RS14500	COG1174	glycine betaine transport
OUQ49_RS14505	COG1174	glycine betaine transport
OUQ49_RS14510	COG1125	glycine betaine transport
OUQ49_RS14510	COG0517	IMP dehydrogenase activity
OUQ49_RS14520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OUQ49_RS14520	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OUQ49_RS14535	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OUQ49_RS14550	COG0302	gtp cyclohydrolase
OUQ49_RS14565	COG0037	tRNA processing
OUQ49_RS14575	COG2027	D-alanyl-D-alanine carboxypeptidase
OUQ49_RS14580	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OUQ49_RS14590	COG0586	Pfam SNARE associated Golgi protein
OUQ49_RS14605	COG0655	NAD(P)H dehydrogenase (quinone) activity
OUQ49_RS14610	COG0076	glutamate decarboxylase activity
OUQ49_RS14630	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS14665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OUQ49_RS14665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OUQ49_RS14695	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
OUQ49_RS14705	COG1725	Transcriptional regulator
OUQ49_RS14720	COG0326	Molecular chaperone. Has ATPase activity
OUQ49_RS14735	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OUQ49_RS14790	COG0419	ATPase involved in DNA repair
OUQ49_RS14820	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OUQ49_RS14825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OUQ49_RS14830	COG1754	DNA topoisomerase type I activity
OUQ49_RS14830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OUQ49_RS14840	COG2890	protein-(glutamine-N5) methyltransferase activity
OUQ49_RS14850	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
OUQ49_RS14860	COG1366	Belongs to the anti-sigma-factor antagonist family
OUQ49_RS14865	COG1111	helicase
OUQ49_RS14865	COG1205	dead DEAH box helicase
OUQ49_RS14925	COG0288	reversible hydration of carbon dioxide
OUQ49_RS14930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OUQ49_RS14935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OUQ49_RS14945	COG2267	carboxylic ester hydrolase activity
OUQ49_RS14975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OUQ49_RS15000	COG0003	Pfam Anion-transporting ATPase
OUQ49_RS15010	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OUQ49_RS15015	COG1610	YqeY-like protein
OUQ49_RS15020	COG1408	metallophosphoesterase
OUQ49_RS15035	COG2755	lipolytic protein G-D-S-L family
OUQ49_RS15045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OUQ49_RS15065	COG1595	DNA-templated transcription, initiation
OUQ49_RS15095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OUQ49_RS15100	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OUQ49_RS15115	COG1802	Transcriptional regulator
OUQ49_RS15125	COG0693	protein deglycase activity
OUQ49_RS15135	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OUQ49_RS15135	COG0515	serine threonine protein kinase
OUQ49_RS15140	COG0738	Major facilitator superfamily
OUQ49_RS15150	COG3226	Transcriptional regulator
OUQ49_RS15165	COG0592	DNA-directed DNA polymerase activity
OUQ49_RS15175	COG0667	Aldo Keto reductase
OUQ49_RS15200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OUQ49_RS15210	COG0662	Cupin 2, conserved barrel domain protein
OUQ49_RS15215	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS15265	COG2076	Multidrug Resistance protein
OUQ49_RS15270	COG0590	tRNA wobble adenosine to inosine editing
OUQ49_RS15280	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OUQ49_RS15285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OUQ49_RS15310	COG2197	response regulator
OUQ49_RS15320	COG0702	epimerase
OUQ49_RS15330	COG3844	kynureninase activity
OUQ49_RS15345	COG0477	Major facilitator Superfamily
OUQ49_RS15350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OUQ49_RS15355	COG0191	fructose-bisphosphate aldolase activity
OUQ49_RS15360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OUQ49_RS15375	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OUQ49_RS15400	COG0542	response to heat
OUQ49_RS15430	COG0789	Transcriptional regulator
OUQ49_RS15435	COG0484	heat shock protein binding
OUQ49_RS15440	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OUQ49_RS15445	COG0443	Heat shock 70 kDa protein
OUQ49_RS15450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OUQ49_RS15455	COG2181	nitrate reductase activity
OUQ49_RS15455	COG0247	lactate metabolic process
OUQ49_RS15475	COG0717	Belongs to the dCTP deaminase family
OUQ49_RS15510	COG1309	transcriptional regulator
OUQ49_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS15530	COG2197	response regulator
OUQ49_RS15550	COG2205	protein histidine kinase activity
OUQ49_RS15555	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS15570	COG1376	ErfK ybiS ycfS ynhG family protein
OUQ49_RS15575	COG3046	protein related to deoxyribodipyrimidine photolyase
OUQ49_RS15580	COG1533	DNA photolyase activity
OUQ49_RS15590	COG2130	NADP-dependent
OUQ49_RS15675	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS15690	COG0367	asparagine synthase
OUQ49_RS15705	COG1902	pentaerythritol trinitrate reductase activity
OUQ49_RS15740	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS15755	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS15765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OUQ49_RS15775	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OUQ49_RS15790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OUQ49_RS15790	COG0519	Catalyzes the synthesis of GMP from XMP
OUQ49_RS15800	COG0318	PFAM AMP-dependent synthetase and ligase
OUQ49_RS15815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUQ49_RS15830	COG1695	Transcriptional regulator
OUQ49_RS15840	COG0667	Aldo Keto reductase
OUQ49_RS15850	COG1609	Transcriptional regulator
OUQ49_RS15875	COG2124	cytochrome p450
OUQ49_RS15880	COG2124	cytochrome p450
OUQ49_RS15905	COG3585	molybdate ion transport
OUQ49_RS15940	COG2801	Transposase and inactivated derivatives
OUQ49_RS15940	COG3415	Transposase
OUQ49_RS15945	COG0475	glutathione-regulated potassium exporter activity
OUQ49_RS15960	COG0513	Belongs to the DEAD box helicase family
OUQ49_RS15965	COG1278	Cold shock
OUQ49_RS16005	COG0454	-acetyltransferase
OUQ49_RS16030	COG2268	Band 7 protein
OUQ49_RS16060	COG0490	domain, Protein
OUQ49_RS16065	COG0475	glutathione-regulated potassium exporter activity
OUQ49_RS16090	COG2255	four-way junction helicase activity
OUQ49_RS16100	COG0180	Tryptophanyl-tRNA synthetase
OUQ49_RS16110	COG2015	COG2015, Alkyl sulfatase and related hydrolases
OUQ49_RS16115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUQ49_RS16175	COG2304	oxidoreductase activity
OUQ49_RS16180	COG2205	protein histidine kinase activity
OUQ49_RS16185	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS16190	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OUQ49_RS16205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OUQ49_RS16220	COG1741	Belongs to the pirin family
OUQ49_RS16230	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS16235	COG1362	aminopeptidase activity
OUQ49_RS16255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OUQ49_RS16310	COG0508	dehydrogenase complex catalyzes the overall conversion of
OUQ49_RS16315	COG0022	dehydrogenase e1 component
OUQ49_RS16340	COG0515	serine threonine protein kinase
OUQ49_RS16345	COG0515	serine threonine protein kinase
OUQ49_RS16360	COG1136	(ABC) transporter
OUQ49_RS16360	COG4591	ABC-type transport system involved in lipoprotein release permease component
OUQ49_RS16375	COG0604	alcohol dehydrogenase
OUQ49_RS16375	COG3321	synthase
OUQ49_RS16375	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS16380	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OUQ49_RS16390	COG0746	molybdenum cofactor guanylyltransferase activity
OUQ49_RS16410	COG1522	sequence-specific DNA binding
OUQ49_RS16415	COG1309	transcriptional regulator
OUQ49_RS16440	COG3396	Phenylacetate-CoA oxygenase
OUQ49_RS16445	COG3460	Phenylacetate-CoA oxygenase
OUQ49_RS16450	COG3396	Phenylacetate-CoA oxygenase
OUQ49_RS16455	COG2151	metal-sulfur cluster biosynthetic enzyme
OUQ49_RS16460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OUQ49_RS16465	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS16470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OUQ49_RS16495	COG1716	ATPase activity
OUQ49_RS16500	COG1716	ATPase activity
OUQ49_RS16515	COG0768	penicillin binding
OUQ49_RS16520	COG0515	serine threonine protein kinase
OUQ49_RS16525	COG3764	Sortase (surface protein transpeptidase)
OUQ49_RS16530	COG3764	Sortase (surface protein transpeptidase)
OUQ49_RS16545	COG3764	Sortase (surface protein transpeptidase)
OUQ49_RS16560	COG0705	Rhomboid family
OUQ49_RS16590	COG0515	serine threonine protein kinase
OUQ49_RS16625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OUQ49_RS16635	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
OUQ49_RS16640	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OUQ49_RS16645	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OUQ49_RS16650	COG0592	DNA-directed DNA polymerase activity
OUQ49_RS16665	COG0594	ribonuclease P activity
OUQ49_RS16670	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OUQ49_RS16675	COG0706	membrane insertase activity
OUQ49_RS16685	COG0357	Ribosomal RNA small subunit methyltransferase G
OUQ49_RS16690	COG1192	Involved in chromosome partitioning
OUQ49_RS16705	COG3118	belongs to the thioredoxin family
OUQ49_RS16710	COG0492	ferredoxin-NADP+ reductase activity
OUQ49_RS16720	COG1595	DNA-templated transcription, initiation
OUQ49_RS16725	COG0515	serine threonine protein kinase
OUQ49_RS16725	COG2815	serine threonine protein kinase
OUQ49_RS16740	COG0617	tRNA 3'-terminal CCA addition
OUQ49_RS16760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OUQ49_RS16785	COG0360	Binds together with S18 to 16S ribosomal RNA
OUQ49_RS16790	COG0629	single-stranded DNA binding
OUQ49_RS16795	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OUQ49_RS16800	COG0359	binds to the 23S rRNA
OUQ49_RS16805	COG0534	Mate efflux family protein
OUQ49_RS16810	COG0305	Participates in initiation and elongation during chromosome replication
OUQ49_RS16840	COG2814	Major facilitator Superfamily
OUQ49_RS16860	COG0626	cystathionine gamma-synthase activity
OUQ49_RS16865	COG1950	PFAM Membrane protein of
OUQ49_RS16870	COG0662	Cupin 2, conserved barrel domain protein
OUQ49_RS16895	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OUQ49_RS16900	COG3152	Membrane
OUQ49_RS16910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OUQ49_RS16915	COG1609	Transcriptional regulator
OUQ49_RS16920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OUQ49_RS16925	COG1271	oxidase subunit
OUQ49_RS16930	COG1294	oxidase, subunit
OUQ49_RS16935	COG4988	ABC transporter
OUQ49_RS16945	COG0561	phosphatase activity
OUQ49_RS16955	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
OUQ49_RS16960	COG0789	Transcriptional regulator
OUQ49_RS16975	COG1131	(ABC) transporter
OUQ49_RS17000	COG0561	phosphatase activity
OUQ49_RS17005	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OUQ49_RS17010	COG0077	Prephenate dehydratase
OUQ49_RS17015	COG2837	iron assimilation
OUQ49_RS17020	COG2372	response to copper ion
OUQ49_RS17030	COG1999	signal sequence binding
OUQ49_RS17050	COG0006	proline dipeptidase activity
OUQ49_RS17070	COG0653	protein targeting
OUQ49_RS17085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OUQ49_RS17160	COG2188	Transcriptional regulator
OUQ49_RS17215	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS17240	COG1595	DNA-templated transcription, initiation
OUQ49_RS17245	COG0318	PFAM AMP-dependent synthetase and ligase
OUQ49_RS17355	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS17360	COG2205	protein histidine kinase activity
OUQ49_RS17370	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OUQ49_RS17385	COG0477	Major facilitator Superfamily
OUQ49_RS17400	COG3467	pyridoxamine 5'-phosphate
OUQ49_RS17405	COG2353	YceI-like domain
OUQ49_RS17415	COG1846	Transcriptional regulator
OUQ49_RS17430	COG1191	sigma factor activity
OUQ49_RS17435	COG1191	sigma factor activity
OUQ49_RS17500	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OUQ49_RS17530	COG4941	Belongs to the sigma-70 factor family
OUQ49_RS17555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OUQ49_RS17580	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
OUQ49_RS17615	COG2815	serine threonine protein kinase
OUQ49_RS17615	COG0515	serine threonine protein kinase
OUQ49_RS17620	COG0492	ferredoxin-NADP+ reductase activity
OUQ49_RS17655	COG0151	Belongs to the GarS family
OUQ49_RS17670	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OUQ49_RS17680	COG2197	response regulator
OUQ49_RS17700	COG1131	(ABC) transporter
OUQ49_RS17720	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OUQ49_RS17725	COG0047	phosphoribosylformylglycinamidine synthase activity
OUQ49_RS17730	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OUQ49_RS17740	COG0739	heme binding
OUQ49_RS17740	COG0741	lytic transglycosylase activity
OUQ49_RS17740	COG1196	nuclear chromosome segregation
OUQ49_RS17760	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OUQ49_RS17795	COG1643	Atp-dependent helicase
OUQ49_RS17805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OUQ49_RS17805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OUQ49_RS17810	COG0785	Cytochrome C biogenesis protein
OUQ49_RS17840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OUQ49_RS17845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OUQ49_RS17855	COG0513	Belongs to the DEAD box helicase family
OUQ49_RS17865	COG1366	Belongs to the anti-sigma-factor antagonist family
OUQ49_RS17875	COG0596	Alpha beta hydrolase
OUQ49_RS17905	COG1191	sigma factor activity
OUQ49_RS17930	COG0789	Transcriptional regulator
OUQ49_RS17940	COG1196	nuclear chromosome segregation
OUQ49_RS17940	COG0741	lytic transglycosylase activity
OUQ49_RS17940	COG0739	heme binding
OUQ49_RS17950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OUQ49_RS17955	COG0579	oxidoreductase
OUQ49_RS17980	COG1252	NADH dehydrogenase
OUQ49_RS17995	COG1846	Transcriptional regulator
OUQ49_RS18065	COG0741	lytic transglycosylase activity
OUQ49_RS18065	COG0739	heme binding
OUQ49_RS18065	COG1196	nuclear chromosome segregation
OUQ49_RS18070	COG0671	phosphoesterase, PA-phosphatase related
OUQ49_RS18085	COG1937	Protein conserved in bacteria
OUQ49_RS18095	COG0306	phosphate transporter
OUQ49_RS18115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OUQ49_RS18120	COG0406	alpha-ribazole phosphatase activity
OUQ49_RS18120	COG0494	nUDIX hydrolase
OUQ49_RS18140	COG1116	anion transmembrane transporter activity
OUQ49_RS18145	COG1725	Transcriptional regulator
OUQ49_RS18155	COG0456	acetyltransferase
OUQ49_RS18175	COG0737	Belongs to the 5'-nucleotidase family
OUQ49_RS18240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OUQ49_RS18245	COG1609	Transcriptional regulator
OUQ49_RS18250	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS18275	COG2897	thiosulfate sulfurtransferase activity
OUQ49_RS18310	COG3485	protocatechuate 3,4-dioxygenase
OUQ49_RS18315	COG0735	belongs to the Fur family
OUQ49_RS18325	COG1490	D-aminoacyl-tRNA deacylase activity
OUQ49_RS18340	COG4552	Acetyltransferase involved in intracellular survival and related
OUQ49_RS18400	COG0475	glutathione-regulated potassium exporter activity
OUQ49_RS18430	COG4770	biotin carboxylase activity
OUQ49_RS18455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OUQ49_RS18485	COG0736	holo-[acyl-carrier-protein] synthase activity
OUQ49_RS18490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OUQ49_RS18515	COG2318	DinB family
OUQ49_RS18525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUQ49_RS18565	COG0438	transferase activity, transferring glycosyl groups
OUQ49_RS18600	COG0588	phosphoglycerate mutase activity
OUQ49_RS18620	COG5002	protein histidine kinase activity
OUQ49_RS18635	COG1329	Transcriptional regulator
OUQ49_RS18640	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OUQ49_RS18645	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OUQ49_RS18655	COG0215	cysteine-tRNA ligase activity
OUQ49_RS18670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OUQ49_RS18680	COG3842	ATPase activity
OUQ49_RS18705	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS18745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OUQ49_RS18785	COG2197	response regulator
OUQ49_RS18790	COG4585	Histidine kinase
OUQ49_RS18800	COG0666	response to abiotic stimulus
OUQ49_RS18830	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OUQ49_RS18850	COG1105	Belongs to the carbohydrate kinase PfkB family
OUQ49_RS18855	COG2801	Transposase and inactivated derivatives
OUQ49_RS18855	COG3415	Transposase
OUQ49_RS18860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OUQ49_RS18880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OUQ49_RS18880	COG1877	trehalose-phosphatase activity
OUQ49_RS18885	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OUQ49_RS18890	COG0463	Glycosyl transferase, family 2
OUQ49_RS18940	COG1132	(ABC) transporter
OUQ49_RS18955	COG1595	DNA-templated transcription, initiation
OUQ49_RS18985	COG0395	ABC-type sugar transport system, permease component
OUQ49_RS18990	COG1175	transmembrane transport
OUQ49_RS19025	COG4251	negative regulation of phosphorylation
OUQ49_RS19030	COG2197	response regulator
OUQ49_RS19055	COG1263	PTS System
OUQ49_RS19055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OUQ49_RS19060	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OUQ49_RS19065	COG1737	Transcriptional regulator
OUQ49_RS19100	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OUQ49_RS19105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OUQ49_RS19110	COG1984	allophanate hydrolase subunit 2
OUQ49_RS19120	COG3142	Participates in the control of copper homeostasis
OUQ49_RS19125	COG3973	AAA domain
OUQ49_RS19145	COG1061	Type III restriction enzyme res subunit
OUQ49_RS19150	COG1846	Transcriptional regulator
OUQ49_RS19175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OUQ49_RS19180	COG1120	ATPase activity
OUQ49_RS19185	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS19190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS19215	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
OUQ49_RS19220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OUQ49_RS19230	COG2814	Major facilitator Superfamily
OUQ49_RS19245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OUQ49_RS19255	COG2252	PERMEase
OUQ49_RS19290	COG0667	Aldo Keto reductase
OUQ49_RS19295	COG2267	carboxylic ester hydrolase activity
OUQ49_RS19305	COG0515	serine threonine protein kinase
OUQ49_RS19310	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS19315	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS19320	COG0583	DNA-binding transcription factor activity
OUQ49_RS19395	COG1051	belongs to the nudix hydrolase family
OUQ49_RS19415	COG1309	transcriptional regulator
OUQ49_RS19425	COG0697	spore germination
OUQ49_RS19480	COG1335	isochorismatase
OUQ49_RS19500	COG1302	Protein conserved in bacteria
OUQ49_RS19515	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OUQ49_RS19545	COG2205	protein histidine kinase activity
OUQ49_RS19550	COG0277	FAD linked oxidase domain protein
OUQ49_RS19550	COG0247	lactate metabolic process
OUQ49_RS19555	COG3896	Chloramphenicol phosphotransferase-like protein
OUQ49_RS19565	COG0583	DNA-binding transcription factor activity
OUQ49_RS19570	COG5006	permease, DMT superfamily
OUQ49_RS19575	COG0494	nUDIX hydrolase
OUQ49_RS19580	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
OUQ49_RS19600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OUQ49_RS19615	COG0318	PFAM AMP-dependent synthetase and ligase
OUQ49_RS19620	COG1024	Enoyl-CoA hydratase
OUQ49_RS19700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OUQ49_RS19715	COG2124	cytochrome p450
OUQ49_RS19740	COG0259	pyridoxamine-phosphate oxidase activity
OUQ49_RS19750	COG0577	efflux transmembrane transporter activity
OUQ49_RS19750	COG1136	(ABC) transporter
OUQ49_RS19755	COG2205	protein histidine kinase activity
OUQ49_RS19760	COG4821	SIS domain
OUQ49_RS19770	COG2267	carboxylic ester hydrolase activity
OUQ49_RS19805	COG0477	Major facilitator Superfamily
OUQ49_RS19815	COG1595	DNA-templated transcription, initiation
OUQ49_RS19880	COG0318	PFAM AMP-dependent synthetase and ligase
OUQ49_RS19890	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS19895	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS19910	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS19915	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS19990	COG1024	Enoyl-CoA hydratase
OUQ49_RS20015	COG2072	flavoprotein involved in K transport
OUQ49_RS20020	COG4592	Periplasmic binding protein
OUQ49_RS20025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS20030	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS20060	COG0501	Belongs to the peptidase M48B family
OUQ49_RS20065	COG0259	pyridoxamine-phosphate oxidase activity
OUQ49_RS20075	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS20085	COG1309	transcriptional regulator
OUQ49_RS20110	COG1024	Enoyl-CoA hydratase
OUQ49_RS20150	COG1278	Cold shock
OUQ49_RS20155	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
OUQ49_RS20165	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
OUQ49_RS20175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OUQ49_RS20180	COG4521	taurine ABC transporter
OUQ49_RS20195	COG2226	methyltransferase
OUQ49_RS20275	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OUQ49_RS20280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OUQ49_RS20285	COG0649	NAD binding
OUQ49_RS20295	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OUQ49_RS20300	COG1034	ATP synthesis coupled electron transport
OUQ49_RS20305	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OUQ49_RS20310	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OUQ49_RS20315	COG0839	Belongs to the complex I subunit 6 family
OUQ49_RS20320	COG0713	ATP synthesis coupled electron transport
OUQ49_RS20325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OUQ49_RS20335	COG1007	ATP synthesis coupled electron transport
OUQ49_RS20340	COG0514	ATP-dependent DNA helicase (RecQ)
OUQ49_RS20365	COG3104	oligopeptide transport
OUQ49_RS20370	COG0142	geranyltranstransferase activity
OUQ49_RS20380	COG1131	(ABC) transporter
OUQ49_RS20405	COG0561	phosphatase activity
OUQ49_RS20445	COG0702	epimerase
OUQ49_RS20450	COG1733	regulation of RNA biosynthetic process
OUQ49_RS20455	COG1013	pyruvate-flavodoxin oxidoreductase activity
OUQ49_RS20460	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OUQ49_RS20460	COG0674	pyruvate-flavodoxin oxidoreductase activity
OUQ49_RS20480	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OUQ49_RS20485	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OUQ49_RS20490	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OUQ49_RS20495	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OUQ49_RS20500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OUQ49_RS20505	COG0839	Belongs to the complex I subunit 6 family
OUQ49_RS20510	COG0713	ATP synthesis coupled electron transport
OUQ49_RS20515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OUQ49_RS20520	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OUQ49_RS20525	COG1007	ATP synthesis coupled electron transport
OUQ49_RS20530	COG1970	mechanosensitive ion channel activity
OUQ49_RS20535	COG0501	Belongs to the peptidase M48B family
OUQ49_RS20540	COG3304	Inner membrane component domain
OUQ49_RS20545	COG2261	transglycosylase associated protein
OUQ49_RS20555	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OUQ49_RS20560	COG1666	GTP binding
OUQ49_RS20590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OUQ49_RS20595	COG2030	dehydratase
OUQ49_RS20605	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OUQ49_RS20620	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OUQ49_RS20625	COG0436	Aminotransferase
OUQ49_RS20645	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OUQ49_RS20650	COG0081	regulation of translation
OUQ49_RS20655	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OUQ49_RS20660	COG0222	ribosome binding
OUQ49_RS20665	COG0085	RNA polymerase activity
OUQ49_RS20670	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OUQ49_RS20775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OUQ49_RS20780	COG0049	tRNA binding
OUQ49_RS20785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OUQ49_RS20790	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OUQ49_RS20815	COG0051	transcription antitermination factor activity, RNA binding
OUQ49_RS20820	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OUQ49_RS20825	COG0088	Forms part of the polypeptide exit tunnel
OUQ49_RS20830	COG0089	rRNA binding
OUQ49_RS20835	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OUQ49_RS20840	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OUQ49_RS20845	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OUQ49_RS20850	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OUQ49_RS20855	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OUQ49_RS20860	COG0255	Belongs to the universal ribosomal protein uL29 family
OUQ49_RS20865	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OUQ49_RS20870	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OUQ49_RS20875	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OUQ49_RS20880	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OUQ49_RS20885	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OUQ49_RS20890	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OUQ49_RS20895	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OUQ49_RS20900	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OUQ49_RS20905	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OUQ49_RS20910	COG1841	ribosomal large subunit assembly
OUQ49_RS20915	COG0200	Binds to the 23S rRNA
OUQ49_RS20925	COG0563	adenylate kinase activity
OUQ49_RS20935	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OUQ49_RS20940	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OUQ49_RS20945	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OUQ49_RS20950	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OUQ49_RS20955	COG0202	RNA polymerase activity
OUQ49_RS20960	COG0203	ribosomal protein L17
OUQ49_RS20965	COG0101	tRNA pseudouridine synthase activity
OUQ49_RS20990	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OUQ49_RS20995	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OUQ49_RS21000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OUQ49_RS21010	COG1072	(Pantothenic acid kinase))
OUQ49_RS21025	COG4566	intracellular signal transduction
OUQ49_RS21035	COG0747	negative chemotaxis
OUQ49_RS21040	COG3795	YCII-related domain
OUQ49_RS21045	COG4941	Belongs to the sigma-70 factor family
OUQ49_RS21070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OUQ49_RS21075	COG0736	holo-[acyl-carrier-protein] synthase activity
OUQ49_RS21085	COG3189	MarR family transcriptional regulator
OUQ49_RS21090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OUQ49_RS21100	COG0802	atpase or kinase
OUQ49_RS21125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OUQ49_RS21160	COG0726	polysaccharide deacetylase
OUQ49_RS21165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OUQ49_RS21175	COG4221	oxidoreductase activity
OUQ49_RS21185	COG0583	DNA-binding transcription factor activity
OUQ49_RS21195	COG2197	response regulator
OUQ49_RS21200	COG1595	DNA-templated transcription, initiation
OUQ49_RS21210	COG0516	GMP reductase activity
OUQ49_RS21225	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OUQ49_RS21240	COG0515	serine threonine protein kinase
OUQ49_RS21245	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS21265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OUQ49_RS21265	COG0519	Catalyzes the synthesis of GMP from XMP
OUQ49_RS21305	COG2197	response regulator
OUQ49_RS21340	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OUQ49_RS21340	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OUQ49_RS21360	COG0714	Associated with various cellular activities
OUQ49_RS21365	COG2425	protein containing a von Willebrand factor type A (vWA) domain
OUQ49_RS21370	COG3552	Protein containing von Willebrand factor type A (VWA) domain
OUQ49_RS21375	COG0045	succinate-CoA ligase (ADP-forming) activity
OUQ49_RS21405	COG0138	bifunctional purine biosynthesis protein purh
OUQ49_RS21420	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OUQ49_RS21435	COG0039	L-malate dehydrogenase activity
OUQ49_RS21440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OUQ49_RS21445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OUQ49_RS21455	COG0754	glutathionylspermidine amidase activity
OUQ49_RS21460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OUQ49_RS21465	COG0180	Tryptophanyl-tRNA synthetase
OUQ49_RS21485	COG1295	ribonuclease BN
OUQ49_RS21490	COG1686	Belongs to the peptidase S11 family
OUQ49_RS21500	COG1408	metallophosphoesterase
OUQ49_RS21530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OUQ49_RS21535	COG1053	succinate dehydrogenase
OUQ49_RS21545	COG2009	succinate dehydrogenase
OUQ49_RS21610	COG1595	DNA-templated transcription, initiation
OUQ49_RS21640	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OUQ49_RS21650	COG1216	Glycosyl transferase, family 2
OUQ49_RS21670	COG1083	cytidylyl-transferase
OUQ49_RS21675	COG2089	acid synthase
OUQ49_RS21685	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OUQ49_RS21685	COG1473	amidohydrolase
OUQ49_RS21690	COG1744	ABC transporter substrate-binding protein PnrA-like
OUQ49_RS21695	COG3845	ABC transporter
OUQ49_RS21700	COG4603	Belongs to the binding-protein-dependent transport system permease family
OUQ49_RS21705	COG1079	Belongs to the binding-protein-dependent transport system permease family
OUQ49_RS21725	COG1404	Belongs to the peptidase S8 family
OUQ49_RS21745	COG2814	Major facilitator Superfamily
OUQ49_RS21750	COG0583	DNA-binding transcription factor activity
OUQ49_RS21765	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OUQ49_RS21790	COG2205	protein histidine kinase activity
OUQ49_RS21795	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS21800	COG1595	DNA-templated transcription, initiation
OUQ49_RS21830	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS21835	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS21850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OUQ49_RS21870	COG1349	DNA-binding transcription factor activity
OUQ49_RS21880	COG4770	biotin carboxylase activity
OUQ49_RS21890	COG0424	maF-like protein
OUQ49_RS21905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OUQ49_RS21920	COG1024	Enoyl-CoA hydratase
OUQ49_RS21950	COG1376	ErfK ybiS ycfS ynhG family protein
OUQ49_RS21965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OUQ49_RS21970	COG1396	sequence-specific DNA binding
OUQ49_RS21985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OUQ49_RS22005	COG1595	DNA-templated transcription, initiation
OUQ49_RS22010	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS22015	COG2202	Pas domain
OUQ49_RS22015	COG2205	protein histidine kinase activity
OUQ49_RS22025	COG2172	sigma factor antagonist activity
OUQ49_RS22030	COG1366	Belongs to the anti-sigma-factor antagonist family
OUQ49_RS22035	COG1366	Belongs to the anti-sigma-factor antagonist family
OUQ49_RS22040	COG2255	four-way junction helicase activity
OUQ49_RS22045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OUQ49_RS22060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OUQ49_RS22070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OUQ49_RS22120	COG0492	ferredoxin-NADP+ reductase activity
OUQ49_RS22125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OUQ49_RS22135	COG0798	PFAM Bile acid sodium symporter
OUQ49_RS22140	COG2072	flavoprotein involved in K transport
OUQ49_RS22155	COG0492	ferredoxin-NADP+ reductase activity
OUQ49_RS22160	COG0640	Transcriptional regulator
OUQ49_RS22190	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
OUQ49_RS22255	COG2188	Transcriptional regulator
OUQ49_RS22265	COG1674	ftsk spoiiie
OUQ49_RS22280	COG4974	Belongs to the 'phage' integrase family
OUQ49_RS22310	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
OUQ49_RS22325	COG1414	Transcriptional regulator
OUQ49_RS22330	COG0251	oxidation-reduction process
OUQ49_RS22335	COG2610	gluconate transmembrane transporter activity
OUQ49_RS22360	COG2894	cell division
OUQ49_RS22390	COG3920	Histidine kinase
OUQ49_RS22395	COG2197	response regulator
OUQ49_RS22415	COG2885	chlorophyll binding
OUQ49_RS22465	COG0667	Aldo Keto reductase
OUQ49_RS22470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OUQ49_RS22475	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OUQ49_RS22490	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OUQ49_RS22495	COG0450	alkyl hydroperoxide reductase
OUQ49_RS22510	COG1136	(ABC) transporter
OUQ49_RS22530	COG4499	WXG100 protein secretion system (Wss), protein YukC
OUQ49_RS22530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OUQ49_RS22545	COG0114	fumarate hydratase activity
OUQ49_RS22555	COG1362	aminopeptidase activity
OUQ49_RS22560	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OUQ49_RS22560	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OUQ49_RS22585	COG0778	Nitroreductase
OUQ49_RS22590	COG1722	exodeoxyribonuclease VII activity
OUQ49_RS22595	COG1570	exodeoxyribonuclease VII activity
OUQ49_RS22605	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OUQ49_RS22620	COG0012	GTP binding
OUQ49_RS22650	COG0789	Transcriptional regulator
OUQ49_RS22690	COG1842	Phage shock protein A
OUQ49_RS22700	COG0463	Glycosyl transferase, family 2
OUQ49_RS22710	COG4941	Belongs to the sigma-70 factor family
OUQ49_RS22715	COG3795	YCII-related domain
OUQ49_RS22750	COG0148	phosphopyruvate hydratase activity
OUQ49_RS22770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OUQ49_RS22775	COG2226	methyltransferase
OUQ49_RS22785	COG1217	gtp-binding protein TYPA
OUQ49_RS22795	COG0747	negative chemotaxis
OUQ49_RS22800	COG0601	transmembrane transport
OUQ49_RS22805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OUQ49_RS22815	COG4608	Belongs to the ABC transporter superfamily
OUQ49_RS22820	COG4166	transmembrane transport
OUQ49_RS22825	COG0601	transmembrane transport
OUQ49_RS22830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OUQ49_RS22840	COG4608	Belongs to the ABC transporter superfamily
OUQ49_RS22845	COG2197	response regulator
OUQ49_RS22860	COG1136	(ABC) transporter
OUQ49_RS22860	COG0577	efflux transmembrane transporter activity
OUQ49_RS22890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OUQ49_RS22920	COG0110	maltose O-acetyltransferase activity
OUQ49_RS22930	COG0515	serine threonine protein kinase
OUQ49_RS22940	COG1132	(ABC) transporter
OUQ49_RS22945	COG1132	(ABC) transporter
OUQ49_RS22950	COG2197	response regulator
OUQ49_RS22955	COG2912	Transglutaminase-like superfamily
OUQ49_RS22985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OUQ49_RS22990	COG1611	Belongs to the LOG family
OUQ49_RS22995	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OUQ49_RS23005	COG0519	Catalyzes the synthesis of GMP from XMP
OUQ49_RS23010	COG1024	Enoyl-CoA hydratase
OUQ49_RS23025	COG1595	DNA-templated transcription, initiation
OUQ49_RS23035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OUQ49_RS23040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OUQ49_RS23075	COG0598	Magnesium transport protein CorA
OUQ49_RS23095	COG2095	MarC family integral membrane protein
OUQ49_RS23105	COG1432	Conserved Protein
OUQ49_RS23120	COG0513	Belongs to the DEAD box helicase family
OUQ49_RS23160	COG0747	negative chemotaxis
OUQ49_RS23165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OUQ49_RS23170	COG0601	transmembrane transport
OUQ49_RS23175	COG4172	Belongs to the ABC transporter superfamily
OUQ49_RS23230	COG0210	DNA helicase
OUQ49_RS23275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OUQ49_RS23325	COG3480	Lon protease (S16) C-terminal proteolytic domain
OUQ49_RS23335	COG1615	UPF0182 protein
OUQ49_RS23360	COG0753	catalase activity
OUQ49_RS23430	COG0483	inositol monophosphate 1-phosphatase activity
OUQ49_RS23440	COG2076	Multidrug Resistance protein
OUQ49_RS23445	COG1162	GTPase activity
OUQ49_RS23450	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OUQ49_RS23460	COG2135	peptidase activity
OUQ49_RS23470	COG1595	DNA-templated transcription, initiation
OUQ49_RS23475	COG5662	AntiSigma factor
OUQ49_RS23485	COG0242	peptide deformylase activity
OUQ49_RS23590	COG1966	Carbon starvation protein
OUQ49_RS23600	COG2182	Extracellular solute-binding protein
OUQ49_RS23605	COG1175	transmembrane transport
OUQ49_RS23610	COG0395	ABC-type sugar transport system, permease component
OUQ49_RS23615	COG1472	Belongs to the glycosyl hydrolase 3 family
OUQ49_RS23620	COG0363	glucosamine-6-phosphate deaminase activity
OUQ49_RS23625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OUQ49_RS23640	COG1597	lipid kinase activity
OUQ49_RS23655	COG2172	sigma factor antagonist activity
OUQ49_RS23715	COG1959	2 iron, 2 sulfur cluster binding
OUQ49_RS23720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OUQ49_RS23725	COG0142	geranyltranstransferase activity
OUQ49_RS23805	COG4106	trans-aconitate 2-methyltransferase activity
OUQ49_RS23810	COG1126	abc transporter atp-binding protein
OUQ49_RS23815	COG0765	amino acid transport
OUQ49_RS23820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUQ49_RS23825	COG0281	malic enzyme
OUQ49_RS23830	COG0604	alcohol dehydrogenase
OUQ49_RS23850	COG0542	response to heat
OUQ49_RS23875	COG0508	dehydrogenase complex catalyzes the overall conversion of
OUQ49_RS23875	COG0567	Dehydrogenase, E1 component
OUQ49_RS23880	COG2205	protein histidine kinase activity
OUQ49_RS23885	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS23905	COG1131	(ABC) transporter
OUQ49_RS23915	COG1595	DNA-templated transcription, initiation
OUQ49_RS23920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OUQ49_RS23925	COG0726	polysaccharide deacetylase
OUQ49_RS24020	COG4974	Belongs to the 'phage' integrase family
OUQ49_RS24025	COG0791	NLP P60 protein
OUQ49_RS24025	COG3883	PFAM NLP P60 protein
OUQ49_RS24040	COG1309	transcriptional regulator
OUQ49_RS24070	COG0768	penicillin binding
OUQ49_RS24085	COG2205	protein histidine kinase activity
OUQ49_RS24105	COG1793	dna ligase
OUQ49_RS24105	COG3285	dna ligase
OUQ49_RS24110	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OUQ49_RS24135	COG0018	arginyl-trna synthetase
OUQ49_RS24140	COG0019	diaminopimelate decarboxylase activity
OUQ49_RS24145	COG0460	homoserine dehydrogenase
OUQ49_RS24150	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OUQ49_RS24155	COG0083	homoserine kinase activity
OUQ49_RS24165	COG1316	TRANSCRIPTIONal
OUQ49_RS24170	COG0254	rRNA binding
OUQ49_RS24175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OUQ49_RS24180	COG2890	protein-(glutamine-N5) methyltransferase activity
OUQ49_RS24190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OUQ49_RS24195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OUQ49_RS24215	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OUQ49_RS24220	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OUQ49_RS24225	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OUQ49_RS24230	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OUQ49_RS24235	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OUQ49_RS24240	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OUQ49_RS24245	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OUQ49_RS24260	COG2197	response regulator
OUQ49_RS24265	COG3850	Histidine kinase
OUQ49_RS24280	COG1250	3-hydroxyacyl-CoA dehydrogenase
OUQ49_RS24295	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
OUQ49_RS24350	COG0183	Belongs to the thiolase family
OUQ49_RS24365	COG3209	COG3209 Rhs family protein
OUQ49_RS24365	COG4104	PAAR repeat-containing protein
OUQ49_RS24385	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS24390	COG5002	protein histidine kinase activity
OUQ49_RS24465	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OUQ49_RS24465	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OUQ49_RS24470	COG1597	lipid kinase activity
OUQ49_RS24505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OUQ49_RS24510	COG0280	phosphate acetyltransferase
OUQ49_RS24510	COG0857	belongs to the CobB CobQ family
OUQ49_RS24515	COG0205	6-phosphofructokinase activity
OUQ49_RS24525	COG4565	transcriptional regulatory protein
OUQ49_RS24530	COG3290	protein histidine kinase activity
OUQ49_RS24535	COG1301	dicarboxylic acid transport
OUQ49_RS24540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OUQ49_RS24545	COG3281	Trehalose synthase
OUQ49_RS24550	COG0366	Alpha amylase catalytic
OUQ49_RS24555	COG0366	Alpha amylase catalytic
OUQ49_RS24560	COG0058	SHG alpha-glucan phosphorylase activity
OUQ49_RS24585	COG1132	(ABC) transporter
OUQ49_RS24590	COG1132	(ABC) transporter
OUQ49_RS24610	COG2197	response regulator
OUQ49_RS24630	COG1024	Enoyl-CoA hydratase
OUQ49_RS24655	COG3415	Transposase
OUQ49_RS24655	COG2801	Transposase and inactivated derivatives
OUQ49_RS24685	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OUQ49_RS24690	COG0142	geranyltranstransferase activity
OUQ49_RS24695	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OUQ49_RS24700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OUQ49_RS24740	COG0477	Major facilitator Superfamily
OUQ49_RS24750	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS24865	COG0823	Involved in the tonB-independent uptake of proteins
OUQ49_RS24875	COG1222	aaa ATPase
OUQ49_RS24900	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS24915	COG2235	arginine
OUQ49_RS24985	COG1760	l-serine dehydratase
OUQ49_RS24990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OUQ49_RS24995	COG0509	glycine decarboxylation via glycine cleavage system
OUQ49_RS25000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OUQ49_RS25020	COG4166	transmembrane transport
OUQ49_RS25025	COG0601	transmembrane transport
OUQ49_RS25030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OUQ49_RS25040	COG4608	Belongs to the ABC transporter superfamily
OUQ49_RS25045	COG2860	membrane
OUQ49_RS25080	COG0482	sulfurtransferase activity
OUQ49_RS25100	COG4221	oxidoreductase activity
OUQ49_RS25110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OUQ49_RS25120	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OUQ49_RS25125	COG0154	amidase activity
OUQ49_RS25135	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OUQ49_RS25140	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OUQ49_RS25150	COG2409	Drug exporters of the RND superfamily
OUQ49_RS25165	COG2133	pyrroloquinoline quinone binding
OUQ49_RS25170	COG0667	Aldo Keto reductase
OUQ49_RS25190	COG0440	acetolactate synthase activity
OUQ49_RS25195	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OUQ49_RS25200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OUQ49_RS25225	COG2508	Transcriptional regulator
OUQ49_RS25230	COG0506	proline dehydrogenase activity
OUQ49_RS25235	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS25250	COG2130	NADP-dependent
OUQ49_RS25265	COG0473	3-isopropylmalate dehydrogenase activity
OUQ49_RS25270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OUQ49_RS25275	COG2957	Belongs to the agmatine deiminase family
OUQ49_RS25285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OUQ49_RS25300	COG4608	Belongs to the ABC transporter superfamily
OUQ49_RS25305	COG0601	transmembrane transport
OUQ49_RS25310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OUQ49_RS25315	COG0444	Belongs to the ABC transporter superfamily
OUQ49_RS25325	COG1472	Belongs to the glycosyl hydrolase 3 family
OUQ49_RS25345	COG2207	Transcriptional regulator
OUQ49_RS25345	COG3708	Transcriptional regulator
OUQ49_RS25365	COG0492	ferredoxin-NADP+ reductase activity
OUQ49_RS25385	COG1733	regulation of RNA biosynthetic process
OUQ49_RS25410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS25415	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS25420	COG1120	ATPase activity
OUQ49_RS25425	COG4607	ABC-type enterochelin transport system periplasmic component
OUQ49_RS25450	COG0366	Alpha amylase catalytic
OUQ49_RS25450	COG1470	cell adhesion involved in biofilm formation
OUQ49_RS25455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OUQ49_RS25475	COG2018	Roadblock/LC7 domain
OUQ49_RS25495	COG2018	Roadblock/LC7 domain
OUQ49_RS25500	COG5002	protein histidine kinase activity
OUQ49_RS25510	COG0179	Fumarylacetoacetate (FAA) hydrolase
OUQ49_RS25515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OUQ49_RS25550	COG1414	Transcriptional regulator
OUQ49_RS25555	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OUQ49_RS25560	COG0066	3-isopropylmalate dehydratase activity
OUQ49_RS25570	COG0776	regulation of translation
OUQ49_RS25580	COG1920	GTP binding
OUQ49_RS25590	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OUQ49_RS25595	COG1181	Belongs to the D-alanine--D-alanine ligase family
OUQ49_RS25610	COG0351	phosphomethylpyrimidine kinase
OUQ49_RS25615	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OUQ49_RS25620	COG1461	Dihydroxyacetone kinase
OUQ49_RS25625	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OUQ49_RS25630	COG0742	ribosomal rna small subunit methyltransferase
OUQ49_RS25635	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OUQ49_RS25650	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OUQ49_RS25655	COG0571	ribonuclease III activity
OUQ49_RS25660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OUQ49_RS25665	COG1733	regulation of RNA biosynthetic process
OUQ49_RS25670	COG2340	Cysteine-rich secretory protein family
OUQ49_RS25675	COG1254	Belongs to the acylphosphatase family
OUQ49_RS25685	COG1196	nuclear chromosome segregation
OUQ49_RS25690	COG0477	Major facilitator Superfamily
OUQ49_RS25725	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OUQ49_RS25745	COG0228	four-way junction DNA binding
OUQ49_RS25750	COG1837	Belongs to the UPF0109 family
OUQ49_RS25755	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OUQ49_RS25760	COG0336	Belongs to the RNA methyltransferase TrmD family
OUQ49_RS25765	COG0335	large ribosomal subunit rRNA binding
OUQ49_RS25780	COG0681	Belongs to the peptidase S26 family
OUQ49_RS25785	COG0681	Belongs to the peptidase S26 family
OUQ49_RS25815	COG1191	sigma factor activity
OUQ49_RS25830	COG0052	Belongs to the universal ribosomal protein uS2 family
OUQ49_RS25835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OUQ49_RS25840	COG0528	UMP kinase activity
OUQ49_RS25845	COG0233	cytoplasmic translational termination
OUQ49_RS25855	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OUQ49_RS25870	COG3842	ATPase activity
OUQ49_RS25885	COG1136	(ABC) transporter
OUQ49_RS25890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OUQ49_RS25900	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS25925	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OUQ49_RS25945	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OUQ49_RS25950	COG3842	ATPase activity
OUQ49_RS25955	COG1176	ABC-type spermidine putrescine transport system, permease component I
OUQ49_RS25960	COG1177	transmembrane transport
OUQ49_RS25965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OUQ49_RS25995	COG2508	Transcriptional regulator
OUQ49_RS26000	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS26010	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OUQ49_RS26015	COG0750	zinc metalloprotease
OUQ49_RS26020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OUQ49_RS26035	COG0442	prolyl-tRNA aminoacylation
OUQ49_RS26055	COG0779	Required for maturation of 30S ribosomal subunits
OUQ49_RS26080	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OUQ49_RS26085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OUQ49_RS26130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OUQ49_RS26135	COG0601	transmembrane transport
OUQ49_RS26140	COG0747	negative chemotaxis
OUQ49_RS26145	COG0455	bacterial-type flagellum organization
OUQ49_RS26165	COG3266	domain, Protein
OUQ49_RS26170	COG1404	Belongs to the peptidase S8 family
OUQ49_RS26185	COG1404	Belongs to the peptidase S8 family
OUQ49_RS26200	COG1674	ftsk spoiiie
OUQ49_RS26210	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OUQ49_RS26215	COG1185	polyribonucleotide nucleotidyltransferase activity
OUQ49_RS26220	COG0612	Peptidase, M16
OUQ49_RS26225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OUQ49_RS26245	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
OUQ49_RS26250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OUQ49_RS26255	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OUQ49_RS26280	COG2208	phosphoserine phosphatase activity
OUQ49_RS26280	COG2770	Histidine kinase
OUQ49_RS26295	COG1674	ftsk spoiiie
OUQ49_RS26305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OUQ49_RS26315	COG1546	Belongs to the CinA family
OUQ49_RS26315	COG1058	Belongs to the CinA family
OUQ49_RS26320	COG1396	sequence-specific DNA binding
OUQ49_RS26325	COG0783	Belongs to the Dps family
OUQ49_RS26335	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS26340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OUQ49_RS26345	COG1201	RNA secondary structure unwinding
OUQ49_RS26350	COG2207	Transcriptional regulator
OUQ49_RS26350	COG1917	Cupin 2, conserved barrel domain protein
OUQ49_RS26385	COG1271	oxidase subunit
OUQ49_RS26390	COG2197	response regulator
OUQ49_RS26405	COG1672	PFAM Archaeal ATPase
OUQ49_RS26405	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
OUQ49_RS26415	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OUQ49_RS26445	COG0765	amino acid transport
OUQ49_RS26450	COG0765	amino acid transport
OUQ49_RS26455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUQ49_RS26460	COG1126	abc transporter atp-binding protein
OUQ49_RS26465	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS26470	COG2205	protein histidine kinase activity
OUQ49_RS26475	COG2358	TRAP transporter, solute receptor (TAXI family
OUQ49_RS26480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OUQ49_RS26495	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OUQ49_RS26505	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OUQ49_RS26510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OUQ49_RS26520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OUQ49_RS26560	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OUQ49_RS26565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OUQ49_RS26570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OUQ49_RS26580	COG4974	Belongs to the 'phage' integrase family
OUQ49_RS26630	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OUQ49_RS26645	COG0514	ATP-dependent DNA helicase (RecQ)
OUQ49_RS26685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OUQ49_RS26690	COG0574	Belongs to the PEP-utilizing enzyme family
OUQ49_RS26690	COG3848	Pyruvate phosphate dikinase
OUQ49_RS26695	COG1309	transcriptional regulator
OUQ49_RS26710	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OUQ49_RS26715	COG2186	Transcriptional regulator
OUQ49_RS26720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OUQ49_RS26745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OUQ49_RS26750	COG4565	transcriptional regulatory protein
OUQ49_RS26755	COG3290	protein histidine kinase activity
OUQ49_RS26765	COG0372	Belongs to the citrate synthase family
OUQ49_RS26770	COG0372	Belongs to the citrate synthase family
OUQ49_RS26780	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OUQ49_RS26785	COG0612	Peptidase, M16
OUQ49_RS26800	COG1802	Transcriptional regulator
OUQ49_RS26805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OUQ49_RS26810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OUQ49_RS26810	COG0045	succinate-CoA ligase (ADP-forming) activity
OUQ49_RS26810	COG1042	CoA-binding domain protein
OUQ49_RS26825	COG1435	thymidine kinase activity
OUQ49_RS26860	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OUQ49_RS26865	COG0483	inositol monophosphate 1-phosphatase activity
OUQ49_RS26875	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS26880	COG2205	protein histidine kinase activity
OUQ49_RS26905	COG0756	dUTP diphosphatase activity
OUQ49_RS26940	COG0569	domain protein
OUQ49_RS26945	COG0531	amino acid
OUQ49_RS26950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OUQ49_RS26975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OUQ49_RS26985	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OUQ49_RS27015	COG4106	trans-aconitate 2-methyltransferase activity
OUQ49_RS27055	COG0515	serine threonine protein kinase
OUQ49_RS27055	COG2815	serine threonine protein kinase
OUQ49_RS27075	COG2366	antibiotic biosynthetic process
OUQ49_RS27095	COG3629	intracellular signal transduction
OUQ49_RS27095	COG3903	Transcriptional regulator
OUQ49_RS27100	COG4585	Histidine kinase
OUQ49_RS27120	COG0596	Alpha beta hydrolase
OUQ49_RS27145	COG0464	growth
OUQ49_RS27155	COG1674	ftsk spoiiie
OUQ49_RS27220	COG2192	nodulation
OUQ49_RS27250	COG0505	Belongs to the CarA family
OUQ49_RS27255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OUQ49_RS27260	COG1280	lysine exporter protein (LysE YggA)
OUQ49_RS27265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OUQ49_RS27275	COG3291	Pkd domain containing protein
OUQ49_RS27280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OUQ49_RS27300	COG3938	Belongs to the proline racemase family
OUQ49_RS27305	COG1802	Transcriptional regulator
OUQ49_RS27330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS27335	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS27345	COG0586	Pfam SNARE associated Golgi protein
OUQ49_RS27350	COG1349	DNA-binding transcription factor activity
OUQ49_RS27355	COG1799	cell septum assembly
OUQ49_RS27375	COG2040	homocysteine
OUQ49_RS27385	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OUQ49_RS27395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OUQ49_RS27400	COG0531	amino acid
OUQ49_RS27410	COG1024	Enoyl-CoA hydratase
OUQ49_RS27440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OUQ49_RS27440	COG2111	Na H antiporter
OUQ49_RS27445	COG1006	Multisubunit Na H antiporter MnhC subunit
OUQ49_RS27450	COG0651	ATP synthesis coupled electron transport
OUQ49_RS27465	COG1320	monovalent cation:proton antiporter activity
OUQ49_RS27480	COG0297	glycogen (starch) synthase activity
OUQ49_RS27485	COG0489	protein tyrosine kinase activity
OUQ49_RS27520	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
OUQ49_RS27525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OUQ49_RS27530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OUQ49_RS27565	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS27575	COG3903	Transcriptional regulator
OUQ49_RS27575	COG3629	intracellular signal transduction
OUQ49_RS27600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OUQ49_RS27605	COG2267	carboxylic ester hydrolase activity
OUQ49_RS27615	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OUQ49_RS27625	COG0406	alpha-ribazole phosphatase activity
OUQ49_RS27635	COG1653	transport
OUQ49_RS27640	COG1175	transmembrane transport
OUQ49_RS27645	COG0395	ABC-type sugar transport system, permease component
OUQ49_RS27650	COG1940	carbohydrate kinase activity
OUQ49_RS27655	COG4213	ABC transporter substrate-binding protein
OUQ49_RS27665	COG4214	carbohydrate transport
OUQ49_RS27670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OUQ49_RS27675	COG0531	amino acid
OUQ49_RS27690	COG1316	TRANSCRIPTIONal
OUQ49_RS27695	COG1024	Enoyl-CoA hydratase
OUQ49_RS27695	COG1250	3-hydroxyacyl-CoA dehydrogenase
OUQ49_RS27700	COG0183	Belongs to the thiolase family
OUQ49_RS27720	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OUQ49_RS27725	COG0446	pyridine nucleotide-disulphide oxidoreductase
OUQ49_RS27735	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OUQ49_RS27740	COG3253	May function as heme-dependent peroxidase
OUQ49_RS27755	COG3220	belongs to the UPF0276 family
OUQ49_RS27780	COG2376	Dihydroxyacetone kinase
OUQ49_RS27790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OUQ49_RS27830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OUQ49_RS27835	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OUQ49_RS27875	COG2072	flavoprotein involved in K transport
OUQ49_RS27940	COG1100	Small GTP-binding protein
OUQ49_RS27965	COG0515	serine threonine protein kinase
OUQ49_RS27965	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OUQ49_RS27970	COG1063	alcohol dehydrogenase
OUQ49_RS27975	COG0156	8-amino-7-oxononanoate synthase activity
OUQ49_RS27990	COG0346	lactoylglutathione lyase activity
OUQ49_RS28010	COG2723	6-phospho-beta-galactosidase activity
OUQ49_RS28065	COG1175	transmembrane transport
OUQ49_RS28085	COG1404	Belongs to the peptidase S8 family
OUQ49_RS28100	COG1132	(ABC) transporter
OUQ49_RS28105	COG1132	(ABC) transporter
OUQ49_RS28115	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OUQ49_RS28125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OUQ49_RS28130	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OUQ49_RS28150	COG0529	Catalyzes the synthesis of activated sulfate
OUQ49_RS28155	COG0175	sulfate reduction
OUQ49_RS28180	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS28200	COG1250	3-hydroxyacyl-CoA dehydrogenase
OUQ49_RS28205	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OUQ49_RS28210	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OUQ49_RS28215	COG0583	DNA-binding transcription factor activity
OUQ49_RS28220	COG0183	Belongs to the thiolase family
OUQ49_RS28225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OUQ49_RS28275	COG1162	GTPase activity
OUQ49_RS28295	COG1404	Belongs to the peptidase S8 family
OUQ49_RS28305	COG0028	Belongs to the TPP enzyme family
OUQ49_RS28325	COG1802	Transcriptional regulator
OUQ49_RS28350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OUQ49_RS28355	COG2252	PERMEase
OUQ49_RS28360	COG3608	succinylglutamate desuccinylase aspartoacylase
OUQ49_RS28360	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OUQ49_RS28385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OUQ49_RS28415	COG0435	Glutathione S-transferase
OUQ49_RS28425	COG2197	response regulator
OUQ49_RS28430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OUQ49_RS28435	COG0318	PFAM AMP-dependent synthetase and ligase
OUQ49_RS28455	COG3960	tartronate-semialdehyde synthase activity
OUQ49_RS28470	COG3629	intracellular signal transduction
OUQ49_RS28470	COG3903	Transcriptional regulator
OUQ49_RS28480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OUQ49_RS28490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OUQ49_RS28500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OUQ49_RS28505	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OUQ49_RS28520	COG0753	catalase activity
OUQ49_RS28525	COG2084	Dehydrogenase
OUQ49_RS28530	COG3622	Belongs to the hyi family
OUQ49_RS28535	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OUQ49_RS28545	COG0395	ABC-type sugar transport system, permease component
OUQ49_RS28550	COG1175	transmembrane transport
OUQ49_RS28560	COG2188	Transcriptional regulator
OUQ49_RS28580	COG2351	hydroxyisourate hydrolase activity
OUQ49_RS28590	COG2233	PERMEase
OUQ49_RS28600	COG2233	PERMEase
OUQ49_RS28645	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OUQ49_RS28660	COG2197	response regulator
OUQ49_RS28680	COG1414	Transcriptional regulator
OUQ49_RS28685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OUQ49_RS28690	COG4266	Belongs to the allantoicase family
OUQ49_RS28695	COG0656	L-ascorbic acid biosynthetic process
OUQ49_RS28700	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS28740	COG0673	inositol 2-dehydrogenase activity
OUQ49_RS28745	COG2188	Transcriptional regulator
OUQ49_RS28760	COG1129	ABC transporter
OUQ49_RS28765	COG1940	carbohydrate kinase activity
OUQ49_RS28775	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OUQ49_RS28780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OUQ49_RS28820	COG1126	abc transporter atp-binding protein
OUQ49_RS28825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUQ49_RS28830	COG0765	amino acid transport
OUQ49_RS28835	COG0765	amino acid transport
OUQ49_RS28845	COG1376	ErfK ybiS ycfS ynhG family protein
OUQ49_RS28860	COG0405	Gamma-glutamyltransferase
OUQ49_RS28890	COG0667	Aldo Keto reductase
OUQ49_RS28900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OUQ49_RS28905	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OUQ49_RS28930	COG2838	Isocitrate dehydrogenase
OUQ49_RS28940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OUQ49_RS28950	COG0095	Lipoate-protein ligase
OUQ49_RS28955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OUQ49_RS28970	COG1024	Enoyl-CoA hydratase
OUQ49_RS28975	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS28995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OUQ49_RS29010	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OUQ49_RS29050	COG1024	Enoyl-CoA hydratase
OUQ49_RS29055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OUQ49_RS29085	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS29090	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS29095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OUQ49_RS29100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OUQ49_RS29110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OUQ49_RS29120	COG1131	(ABC) transporter
OUQ49_RS29125	COG1024	Enoyl-CoA hydratase
OUQ49_RS29155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OUQ49_RS29170	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OUQ49_RS29185	COG1929	Belongs to the glycerate kinase type-1 family
OUQ49_RS29205	COG0559	Belongs to the binding-protein-dependent transport system permease family
OUQ49_RS29210	COG0559	Belongs to the binding-protein-dependent transport system permease family
OUQ49_RS29240	COG0688	phosphatidylethanolamine metabolic process
OUQ49_RS29245	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS29255	COG2301	Belongs to the HpcH HpaI aldolase family
OUQ49_RS29260	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OUQ49_RS29260	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OUQ49_RS29265	COG0604	alcohol dehydrogenase
OUQ49_RS29270	COG0456	acetyltransferase
OUQ49_RS29285	COG1250	3-hydroxyacyl-CoA dehydrogenase
OUQ49_RS29320	COG0667	Aldo Keto reductase
OUQ49_RS29330	COG2362	D-Aminopeptidase
OUQ49_RS29335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OUQ49_RS29345	COG1619	proteins homologs of microcin C7 resistance protein MccF
OUQ49_RS29360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OUQ49_RS29375	COG4106	trans-aconitate 2-methyltransferase activity
OUQ49_RS29395	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OUQ49_RS29420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OUQ49_RS29435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OUQ49_RS29435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OUQ49_RS29465	COG2154	pterin-4-alpha-carbinolamine dehydratase
OUQ49_RS29475	COG4106	trans-aconitate 2-methyltransferase activity
OUQ49_RS29485	COG0656	L-ascorbic acid biosynthetic process
OUQ49_RS29495	COG0583	DNA-binding transcription factor activity
OUQ49_RS29515	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OUQ49_RS29520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OUQ49_RS29530	COG1129	ABC transporter
OUQ49_RS29535	COG1172	Belongs to the binding-protein-dependent transport system permease family
OUQ49_RS29545	COG0673	inositol 2-dehydrogenase activity
OUQ49_RS29625	COG1129	ABC transporter
OUQ49_RS29635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OUQ49_RS29640	COG1869	D-ribose catabolic process
OUQ49_RS29665	COG5002	protein histidine kinase activity
OUQ49_RS29670	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS29700	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS29710	COG4175	Glycine betaine
OUQ49_RS29710	COG0517	IMP dehydrogenase activity
OUQ49_RS29715	COG4176	ABC-type proline glycine betaine transport system permease component
OUQ49_RS29725	COG2124	cytochrome p450
OUQ49_RS29730	COG2985	domain, Protein
OUQ49_RS29730	COG0569	domain protein
OUQ49_RS29745	COG1070	Carbohydrate kinase
OUQ49_RS29755	COG1940	carbohydrate kinase activity
OUQ49_RS29780	COG1846	Transcriptional regulator
OUQ49_RS29805	COG2124	cytochrome p450
OUQ49_RS29810	COG1486	melibiose metabolic process
OUQ49_RS29850	COG3012	SEC-C Motif Domain Protein
OUQ49_RS29905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OUQ49_RS29930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OUQ49_RS29965	COG2770	Histidine kinase
OUQ49_RS29965	COG2208	phosphoserine phosphatase activity
OUQ49_RS29985	COG1793	dna ligase
OUQ49_RS30065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OUQ49_RS30070	COG0488	(ABC) transporter
OUQ49_RS30085	COG1515	deoxyribonuclease V activity
OUQ49_RS30095	COG3268	Saccharopine dehydrogenase
OUQ49_RS30100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OUQ49_RS30105	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS30110	COG0183	Belongs to the thiolase family
OUQ49_RS30115	COG1024	Enoyl-CoA hydratase
OUQ49_RS30115	COG1250	3-hydroxyacyl-CoA dehydrogenase
OUQ49_RS30120	COG0789	Transcriptional regulator
OUQ49_RS30145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OUQ49_RS30165	COG0488	(ABC) transporter
OUQ49_RS30170	COG2183	response to ionizing radiation
OUQ49_RS30180	COG4977	sequence-specific DNA binding
OUQ49_RS30190	COG1024	Enoyl-CoA hydratase
OUQ49_RS30205	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
OUQ49_RS30240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OUQ49_RS30255	COG1134	teichoic acid transport
OUQ49_RS30255	COG1388	LysM domain
OUQ49_RS30260	COG1562	ergosterol biosynthetic process
OUQ49_RS30270	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OUQ49_RS30280	COG1657	PFAM Prenyltransferase squalene oxidase
OUQ49_RS30310	COG2365	Tyrosine phosphatase family
OUQ49_RS30320	COG2755	lipolytic protein G-D-S-L family
OUQ49_RS30330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OUQ49_RS30370	COG3467	pyridoxamine 5'-phosphate
OUQ49_RS30410	COG1609	Transcriptional regulator
OUQ49_RS30415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OUQ49_RS30425	COG1116	anion transmembrane transporter activity
OUQ49_RS30455	COG3958	Transketolase
OUQ49_RS30460	COG3959	Transketolase, thiamine diphosphate binding domain
OUQ49_RS30480	COG0456	acetyltransferase
OUQ49_RS30480	COG1846	Transcriptional regulator
OUQ49_RS30515	COG1215	transferase activity, transferring glycosyl groups
OUQ49_RS30540	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS30555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OUQ49_RS30570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OUQ49_RS30590	COG0318	PFAM AMP-dependent synthetase and ligase
OUQ49_RS30615	COG3511	phospholipase C
OUQ49_RS30625	COG2197	response regulator
OUQ49_RS30630	COG3851	Histidine kinase
OUQ49_RS30640	COG0247	lactate metabolic process
OUQ49_RS30645	COG1139	Iron-sulfur cluster binding protein
OUQ49_RS30650	COG1556	Lactate utilization protein
OUQ49_RS30670	COG1672	PFAM Archaeal ATPase
OUQ49_RS30670	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
OUQ49_RS30680	COG0318	PFAM AMP-dependent synthetase and ligase
OUQ49_RS30690	COG0156	8-amino-7-oxononanoate synthase activity
OUQ49_RS30705	COG0604	alcohol dehydrogenase
OUQ49_RS30705	COG3321	synthase
OUQ49_RS30715	COG0604	alcohol dehydrogenase
OUQ49_RS30715	COG3321	synthase
OUQ49_RS30720	COG1250	3-hydroxyacyl-CoA dehydrogenase
OUQ49_RS30745	COG3629	intracellular signal transduction
OUQ49_RS30745	COG3903	Transcriptional regulator
OUQ49_RS30770	COG1396	sequence-specific DNA binding
OUQ49_RS30770	COG3800	Transcriptional regulator
OUQ49_RS30775	COG2079	MmgE PrpD family protein
OUQ49_RS30810	COG1316	TRANSCRIPTIONal
OUQ49_RS30820	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
OUQ49_RS30825	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OUQ49_RS30830	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OUQ49_RS30855	COG0714	Associated with various cellular activities
OUQ49_RS30880	COG0831	urea catabolic process
OUQ49_RS30890	COG0831	urea catabolic process
OUQ49_RS30890	COG0832	Belongs to the urease beta subunit family
OUQ49_RS30895	COG0804	urea catabolic process
OUQ49_RS30900	COG0830	nickel cation binding
OUQ49_RS30905	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OUQ49_RS30910	COG0829	nickel cation binding
OUQ49_RS30945	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS30970	COG0446	pyridine nucleotide-disulphide oxidoreductase
OUQ49_RS30970	COG1902	pentaerythritol trinitrate reductase activity
OUQ49_RS30985	COG2409	Drug exporters of the RND superfamily
OUQ49_RS30990	COG1846	Transcriptional regulator
OUQ49_RS31045	COG1233	COG1233 Phytoene dehydrogenase and related
OUQ49_RS31050	COG2130	NADP-dependent
OUQ49_RS31055	COG2124	cytochrome p450
OUQ49_RS31070	COG2080	2 iron, 2 sulfur cluster binding
OUQ49_RS31075	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OUQ49_RS31080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OUQ49_RS31095	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OUQ49_RS31105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OUQ49_RS31120	COG0019	diaminopimelate decarboxylase activity
OUQ49_RS31130	COG2837	iron assimilation
OUQ49_RS31135	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OUQ49_RS31175	COG0596	Alpha beta hydrolase
OUQ49_RS31185	COG0395	ABC-type sugar transport system, permease component
OUQ49_RS31190	COG1175	transmembrane transport
OUQ49_RS31200	COG1940	carbohydrate kinase activity
OUQ49_RS31210	COG1652	LysM domain
OUQ49_RS31245	COG0784	Response regulator, receiver
OUQ49_RS31250	COG4251	negative regulation of phosphorylation
OUQ49_RS31255	COG2201	protein-glutamate methylesterase activity
OUQ49_RS31260	COG1191	sigma factor activity
OUQ49_RS31305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OUQ49_RS31325	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OUQ49_RS31330	COG3275	phosphorelay sensor kinase activity
OUQ49_RS31405	COG0583	DNA-binding transcription factor activity
OUQ49_RS31415	COG1053	succinate dehydrogenase
OUQ49_RS31420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OUQ49_RS31435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OUQ49_RS31440	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OUQ49_RS31450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OUQ49_RS31455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OUQ49_RS31460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OUQ49_RS31490	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OUQ49_RS31500	COG2197	response regulator
OUQ49_RS31510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OUQ49_RS31525	COG3360	Dodecin
OUQ49_RS31545	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
OUQ49_RS31550	COG0121	glutamine amidotransferase
OUQ49_RS31555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OUQ49_RS31560	COG3572	ergothioneine biosynthetic process
OUQ49_RS31585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OUQ49_RS31590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OUQ49_RS31595	COG1834	amidinotransferase
OUQ49_RS31610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OUQ49_RS31625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OUQ49_RS31650	COG1028	Short-chain dehydrogenase reductase Sdr
OUQ49_RS31680	COG0243	molybdopterin cofactor binding
OUQ49_RS31705	COG0747	negative chemotaxis
OUQ49_RS31710	COG0601	transmembrane transport
OUQ49_RS31715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OUQ49_RS31720	COG0444	Belongs to the ABC transporter superfamily
OUQ49_RS31725	COG4608	Belongs to the ABC transporter superfamily
OUQ49_RS31730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUQ49_RS31735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OUQ49_RS31745	COG0431	NADPH-dependent FMN reductase
OUQ49_RS31795	COG1120	ATPase activity
OUQ49_RS31805	COG0477	Major facilitator Superfamily
OUQ49_RS31810	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OUQ49_RS31820	COG0254	rRNA binding
OUQ49_RS31825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OUQ49_RS31830	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OUQ49_RS31835	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OUQ49_RS31855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS31860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS31865	COG1120	ATPase activity
OUQ49_RS31900	COG1132	(ABC) transporter
OUQ49_RS31945	COG0438	transferase activity, transferring glycosyl groups
OUQ49_RS31970	COG0438	transferase activity, transferring glycosyl groups
OUQ49_RS31970	COG0297	glycogen (starch) synthase activity
OUQ49_RS32010	COG1174	glycine betaine transport
OUQ49_RS32015	COG1174	glycine betaine transport
OUQ49_RS32035	COG0517	IMP dehydrogenase activity
OUQ49_RS32035	COG1125	glycine betaine transport
OUQ49_RS32045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OUQ49_RS32065	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS32070	COG1960	acyl-CoA dehydrogenase activity
OUQ49_RS32085	COG0601	transmembrane transport
OUQ49_RS32090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OUQ49_RS32095	COG0444	Belongs to the ABC transporter superfamily
OUQ49_RS32160	COG1796	DNA polymerase
OUQ49_RS32160	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OUQ49_RS32245	COG1278	Cold shock
OUQ49_RS32260	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OUQ49_RS32280	COG4044	May play a role in the intracellular transport of hydrophobic ligands
OUQ49_RS32320	COG5297	Belongs to the glycosyl hydrolase family 6
OUQ49_RS32330	COG5001	Diguanylate cyclase
OUQ49_RS32330	COG3300	MHYT domain
OUQ49_RS32345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OUQ49_RS32345	COG2146	nitrite reductase [NAD(P)H] activity
OUQ49_RS32350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OUQ49_RS32350	COG2146	nitrite reductase [NAD(P)H] activity
OUQ49_RS32355	COG0243	molybdopterin cofactor binding
OUQ49_RS32360	COG2223	nitrite transmembrane transporter activity
OUQ49_RS32415	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OUQ49_RS32445	COG0745	RESPONSE REGULATOR receiver
OUQ49_RS32455	COG1120	ATPase activity
OUQ49_RS32510	COG4585	Histidine kinase
OUQ49_RS32515	COG2197	response regulator
OUQ49_RS32525	COG1136	(ABC) transporter
OUQ49_RS32525	COG0577	efflux transmembrane transporter activity
OUQ49_RS32540	COG1012	belongs to the aldehyde dehydrogenase family
OUQ49_RS32560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OUQ49_RS32565	COG3239	Fatty acid desaturase
OUQ49_RS32600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OUQ49_RS32605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OUQ49_RS32610	COG0640	Transcriptional regulator
OUQ49_RS32625	COG2018	Roadblock/LC7 domain
OUQ49_RS32665	COG1024	Enoyl-CoA hydratase
OUQ49_RS32705	COG1595	DNA-templated transcription, initiation
OUQ49_RS32725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OUQ49_RS32735	COG2340	Cysteine-rich secretory protein family
OUQ49_RS32765	COG0488	(ABC) transporter
OUQ49_RS32780	COG0009	L-threonylcarbamoyladenylate synthase
OUQ49_RS32815	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
OUQ49_RS32835	COG0142	geranyltranstransferase activity
OUQ49_RS32840	COG3250	beta-galactosidase activity
OUQ49_RS32840	COG5297	Belongs to the glycosyl hydrolase family 6
OUQ49_RS32855	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OUQ49_RS32870	COG1891	lyase activity
OUQ49_RS32880	COG2890	protein-(glutamine-N5) methyltransferase activity
OUQ49_RS32920	COG1175	transmembrane transport
OUQ49_RS32925	COG0395	ABC-type sugar transport system, permease component
OUQ49_RS32930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OUQ49_RS32935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OUQ49_RS32945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OUQ49_RS32970	COG2367	Beta-lactamase
OUQ49_RS33020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUQ49_RS33025	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OUQ49_RS33290	COG2188	Transcriptional regulator